Patent ID: 9096907
Filing Date: 2015-08-04
Classification: C12Q,G01N

Abstract:
1. A method for treating prostate cancer in a patient comprising: a) obtaining a biological sample from said patient; b) performing a first hybridization and/or amplification assay on mRNA or cDNA derived from said sample using at least a first oligonucleotide specific for a prostate cancer associated PCA3 mRNA or cDNA; c) determining the amount of said prostate cancer associated PCA3 mRNA or cDNA and the amount of a prostate-specific marker in said biological sample; d) determining a first ratio value of said amount of said prostate cancer associated PCA3 mRNA or cDNA over said amount of prostate-specific marker; e) comparing said first ratio value to at least one predetermined cut-off value; f) identifying said patient as having a more aggressive prostate cancer when the ratio value is above said predetermined cut-off value; and g) administering to said patient a prostate cancer treatment for a more aggressive prostate cancer.