Patent ID: 6290972
Filing Date: 2001-09-18
Classification: A61K,C07K,C12N,Y10S

Abstract:
A method for augmenting a vaccine response comprising administering an adjuvant to a mammal, wherein the adjuvant comprises an oligomeric soluble polypeptide encoded by a DNA molecule selected from the group consisting of:(a) a DNA molecule comprising nucleotides 139 through 780 of SEQ ID NO: 1;(b) a DNA molecule comprising nucleotides 355 through 780 of SEQ ID NO: 1;(c) a DNA molecule comprising nucleotides 184 through 828 of SEQ ID NO: 11;(d) a DNA molecule comprising nucleotides 196 through 828 of SEQ ID NO: 11;(e) a DNA molecule comprising nucleotides 382 through 828 of SEQ ID NO: 11;(f) a DNA molecule comprising nucleotides 403 through 828 of SEQ ID NO: 11; and(g) a DNA molecule comprising nucleotides sequences that due to the degeneracy of the genetic code encode the polypeptides encoded by the DNA molecules of (a)-(g).