Patent ID: 6664271
Filing Date: 2003-12-16
Classification: A61P,C07D

Abstract:
An immune system stimulating compound selected from ethyl 1-phenylacetyl-3-piperidinecarboxylate; ethyl 1-(4-fluorobenzoyl)-3-piperidinecarboxylate; ethyl (2-thiophenecarbonyl)-3-piperidinecarboxylate; ethyl 1-(2-thiopheneacetyl) -3-piperidinecarboxylate; ethyl 1-(N-methylaminocarbonyl)-4-oxo-3-piperidinecarboxylate; ethyl 1-(4-fluorobenzoyl)-4-oxo-3-piperidinecarboxylate; n-butyl 1-benzoyl-3-piperidinecarboxylate; N-ethyl 1-benzoyl-3-piperidinecarboxamide; N-(n-octyl) 1-benzoyl-3-piperidinecarboxamide; N-ethyl 1-(2-thiopheneacetyl-3-piperidinecarboxamide; ethyl 1-(3-(2-thienyl)propionyl)-3-piperidinecarboxylate; 2-dimethylaminoethyl 1-(2-thiopheneacetyl)-3-piperidinecarboxamide; 1-benzoyl-3-butyrylpiperidine; (S)-ethyl 1-(2-thiopheneacetyl)-3-piperidinecarboxylate; ethyl 1-(2-thiopheneacetyl-6-methyl-3-piperidinecarboxylate; ethyl 1-benzyl-3-piperidinecarboxylate 1-methiodide; ethyl 1-(4-phenylbenzoyl)-3-piperidinecarboxylate; (S)-1-(2-thiopheneacetyl)-3-piperidine carboxylic acid; 8-[(methylamino)carbonyl]-3-oxo-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester; 1-(2-thiopheneacetyl-3-hydroxypiperidine; (S)-1-(2-thiopheneacetyl)-3-piperidinecarboxylic acid ammonium salt; ethyl 1-(1-phenylpropionyl)-3-piperidinecarboxylate; 1-(2-thiopheneacetyl)-3-(O-methanesulfonyl)piperidine; ethyl 1-(2-bromobenzoyl)-2-acetylpiperidinecarboxylate; 1-(2-thiopheneacetyl)-3-(O-propionyl)piperidine; (S)-ethyl 1-(N-benzylurea)-3-piperidinecarboxylate; (S)-ethyl 1-(N-methylurea)-3-piperidinecarboxylate; (S)-1-benzoyl-3-piperidinecarboxylic acid; (S)-methyl 1-benzoyl-3-piperidinecarboxylate; (S)-propyl 1-benzoyl-3-piperidinecarboxylate; (S)-ethyl 1-(2-thienylpropyl)-3-piperidinecarboxylate; ethyl 1-(2-thiopheneacetyl)-5-methyl-3-piperidinecarboxylate; (S)Â±ethyl 1-(2-phenylpropionyl)-3-piperidinecarboxylate; (S)-ethyl 1-(2-thiopheneacetyl)-3-hydroxymethylpiperidine; ethyl 1-(2-thiopheneacetyl)-4-methyl-3-piperidinecarboxylate; (S)-1-(2-thiopheneacetyl)-3-piperidinecarboxaldehyde; (S)-1-(2-thiopheneacetyl)-3-piperidinonitrile; (S)-ethyl 1-benzyl-3-piperidinecarboxylate 1-methiodide; (S)-N,N-dimethyl 1-benzyl-3-piperidinecarboxamide 1-methiodide or a physiologically acceptable salt of one of the foregoing.