Patent ID: 8580776
Filing Date: 2013-11-12
Classification: A61K,A61P

Abstract:
1. A method of slowing progression of a demyelinating disease that is multiple sclerosis or Alzheimer's disease in a mammal comprising the step of administering to a mammal suffering from a demyelinating disease a therapeutically effective amount of an agent that increases noradrenaline levels in the mammal's CNS and a noradrenaline reuptake inhibitor, wherein the agent comprises a noradrenaline precursor that is (−)-threo-3-(3,4-dihydroxyphenyl)-L-serine (L-DOPS) and wherein the reuptake inhibitor that is desipramine, atomoxetine, reboxetine, viloxazine, maprotiline, nortriptyline, bupropion, or radafaxine.