Patent ID: 9096496
Filing Date: 2015-08-04
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A compound of formula e: where: R where R 20 is selected from the group consisting of C 1-6 alkyl, —O—C 1-6 alkyl, C 3-7 cycloalkyl, —O—C 3-7 cycloalkyl, phenyl, —O-phenyl, —NR 21 R 22 , —CH(R 25 )—NH 2 , —CH(R 25 )—NHC(O)O—C 1-6 alkyl, and —CH(NH 2 )CH 2 COOCH 3 ; and R 21 and R 22 are independently selected from the group consisting of H, C 1-6 alkyl, and benzyl; or R 21 and R 22 are taken together as —(CH 2 ) 3-6 —, —C(O)—(CH 2 ) 3 —, or —(CH 2 ) 2 O(CH 2 ) 2 —; R 23 is selected from the group consisting of −O—C 1-6 alkyl, —O-benzyl, and —NR 21 R 22 ; R 24 is C 1-6 alkyl or C 0-6 alkylene-C 6-10 aryl; and R 25 is H, —CH 3 , —CH(CH 3 ), phenyl, or benzyl; R R R R or a pharmaceutically acceptable salt thereof.