Patent ID: 8357652
Filing Date: 2013-01-22
Classification: A61K,A61N,A61P,C07K,C12N

Abstract:
1. A method comprising: administering to a subject having cancer selected from breast cancer, ovarian or cervical cancer, prostate cancer, lung cancer, and liver cancer, a therapeutically effective amount of fibrillar human serum albumin, wherein the fibrillar human serum albumin is produced by a method comprising: dissolving human serum albumin in a suitable detergent; sonicating the human serum albumin; applying the sonicated human serum albumin to a gel filtration column with a separation range above 70 kDa molecular weight; so as to promote column-induced fibrillar protein formation and to separate globular protein from fibrillar protein; eluting the fibrillar human serum albumin from the column with a buffer containing a low concentration of detergent; collecting eluent containing fibrillar human serum albumin from the column, and dialyzing the eluant to remove the detergent.