Patent ID: 7223363
Filing Date: 2007-05-29
Classification: B01F,B01J,B01L,C40B,G01N

Abstract:
1. An interface device for interfacing to a surface of a substrate bearing a biological sample immobilized on a first surface thereof, comprising: a. a main interface layer having a substantially planar interface surface adapted to conform to and interface with the first surface of the substrate to which the biological sample is immobilized; b. a substantially planar gasket positioned at said interface surface and having at least one opening formed therethrough, wherein inside walls in the at least one opening of said gasket define the inside walls of an interface channel; c. an inlet channel formed in said main interface layer and opening into said at least one opening; d. an outlet channel formed in said main interface layer and opening into said at least one opening; and e. at least one air bladder formed in said main interface layer adjacent said interface surface, wherein said at least one air bladder has a flexible lower surface defined by a substantially planar flexible gas-impermeable diaphragm layer having a portion disposed between the main interface layer and the gasket and a portion defining the flexible lower surface of the air bladder, wherein the flexible lower surface is capable of being deflected outward as said air bladder is inflated or inward as said air bladder is deflated, and wherein said air bladder communicates with at least one air channel that passes through said main interface layer and is adapted for connection with a pressure source.