Patent ID: 7968697
Filing Date: 2011-06-28
Classification: A61K,A61P,C07K,C12N

Abstract:
1. A purified or isolated nucleic acid encoding a polypeptide comprising an NS3/NS4A polypeptide with enhanced protease activity, wherein said NS3/4A polypeptide is selected from the group consisting of SEQ ID NO: 45, SEQ ID NO: 50, SEQ ID NO: 52, SEQ ID NO: 53, SEQ ID NO: 69, SEQ ID NO: 91, SEQ ID NO: 97, SEQ ID NO: 98, SEQ ID NO: 103, SEQ ID NO: 112, SEQ ID NO: 115, SEQ ID NO: 125, SEQ ID NO: 150, SEQ ID NO: 161, SEQ ID NO: 173, SEQ ID NO: 175, SEQ ID NO: 180, SEQ ID NO: 197, SEQ ID NO: 200, SEQ ID NO: 205, and SEQ ID NO: 216.