Patent ID: 7112589
Filing Date: 2006-09-26
Classification: A61P,C07D

Abstract:
1. A compound of formula I, or a pharmaceutically acceptable salt thereof wherein R is H, —R4, —OR4 or NR3R4, wherein R3 is H, lower alkyl or C R4 is lower alkyl or C wherein R3 and R4 are independently, optionally substituted by halo, hydroxy, lower alkoxy, CN, NO R1 is —CO—NR5R6, —NH—CO—R5, —CH wherein R5 is aryl, aryl-lower alkyl, C R6 is H, aryl, aryl-lower alkyl, aryl-lower-alkenyl, C wherein R5 and R6 together with the nitrogen atom to which they attached are joined to form an N-heterocyclyl group, wherein N-heterocyclyl denotes a saturated, partially unsaturated or aromatic nitrogen containing heterocyclic moiety attached via a nitrogen atom thereof having from 3 to 8 ring atoms optionally containing a further 1, 2 or 3 heteroatoms selected from N, NR7, O, S, S(O) or S(O) wherein heterocyclyl denotes a ring having from 3 to 10 ring members and containing from 1 to 3 heteroatoms selected from N, NR7, O, S, S(O) or S(O) wherein R5 and R6 are independently, optionally substituted by one or more groups, selected from halo, hydroxy, oxo, lower alkoxy, CN and NO R2 is is independently H, or optionally substituted with lower alkyl, aryl, aryl-lower alkyl, C wherein R2 is optionally substituted by halo, hydroxy, oxo, lower alkoxy, CN, NO