Patent ID: 8323616
Filing Date: 2012-12-04
Classification: A61K,C07B,C07D

Abstract:
1. A process for the production of an 18 F-labelled tracer which comprises treatment of a solid support-bound precursor of formula (Ib) wherein Y wherein at each occurrence, k is an integer of 0 to 3, n is an integer of 1 to 16, and R wherein each phenyl ring is optionally substituted by 1 to 4 groups selected from C wherein: R R R provided that only one of R with wherein the TRACER is as defined for the compound of formula (Ib) except that one of R optionally followed by: (i) removal of excess (ii) removal of any protecting groups; and/or (iii) removal of organic solvent; and/or (iv) formulation of the resultant compound of formula (IIb) as an aqueous solution.