Patent ID: 6939873
Filing Date: 2005-09-06
Classification: A61K

Abstract:
1. A pharmaceutical composition, comprising as active material a non-sedative barbiturate, together with a pharmaceutically acceptable carrier, the composition being non-sedative and non-hypnotic when administered at a dose which is neuroprotective, the barbiturate having the structure wherein R phenyl; C(O)XR CXR CH(XR aryl optionally containing one or more heteroatoms selected from the group consisting of N, S, and O; lower acyloxy; phenyl substituted with lower acyl group or derivative thereof or acetamide; benzyl; benzyl substituted on the ring by one or more halogens, lower alkyl groups or both; cycloalkyl, which optionally contains one or more heteroatoms selected from the group consisting of N, O, and S; lower alkyl; or lower alkyl substituted with an aromatic moiety; provided that at least one of R when one of R