Patent ID: 7531548
Filing Date: 2009-05-12
Classification: A61P,C07D

Abstract:
1. A compound of formula a N-oxide, a pharmaceutically acceptable addition salt, or a stereochemically isomeric form thereof, wherein n is 0, 1, 2, 3; m is 0, 1, 2, 3; each R each R R X R R R each Alk or Alk′ independently is a bivalent C L is aryl or Het; Y is O, S, —S(═O) Het is a 5- or 6-membered completely unsaturated ring system wherein one, two, three or four ring members are hetero atoms each independently selected from the group consisting of nitrogen, oxygen and sulfur, and wherein the remaining ring members are carbon atoms; and, where possible, any nitrogen ring member may optionally be substituted with C Het Q is hydrogen, C R each aryl is phenyl or phenyl substituted with one, two, three, four or five substituents each independently selected from halo, hydroxy, mercapto, C