Patent ID: 8620433
Filing Date: 2013-12-31
Classification: A61N

Abstract:
1. A method of cardiac pacing employing a right ventricular electrode and a plurality of left ventricular electrodes, comprising: a) pacing using the right ventricular electrode and a pacing left ventricular electrode using a first V-V delay; b) measuring activation times at other ones of the left ventricular electrodes in response to pacing the right ventricular electrode and pacing a left ventricular electrode; c) determining a weighted electrical dyssynchrony associated with the first V-V delay; d) pacing using the right ventricular electrode and the pacing left ventricular electrodes using a second V-V delay; e) measuring activation times at other ones of the left ventricular electrodes in response to pacing the right ventricular electrode and pacing a left ventricular electrode; and f) determining a weighted electrical dyssynchrony for the second V-V delay; g) comparing weighted electrical dyssynchrony for the first and the second V-V delays; and h) selecting an optimal V-V delay in response to comparing weighted electrical dyssynchrony for the first and the second V-V delays, wherein the weighted electrical dyssynchrony is determined through a weighted electrical dyssynchrony equation (“(ED(j,A,D)”) defined as: wherein factor w(i, j) is a distance of a sensing electrode i from a pacing electrode j, n is a total number of left ventricular electrodes, A is atrio-ventricular delay, and D is time delay between pacing pulses in a right ventricle and a left ventricle.