Patent ID: 6864232
Filing Date: 2005-03-08
Classification: A61K

Abstract:
1. A method for treating retinopathy, comprising administering to a subject in need thereof an effective amount of an agent comprising a tricyclo compound of formula (I) wherein adjacent pairs of R 1 and R 2 , R 3 and R 4 , and R 5 and R 6 each independently a) consist of two adjacent hydrogen atoms, wherein R b) form another bond optionally between carbon atoms binding with the members of said pairs; R R R X is oxo, (hydrogen atom, hydroxy), (hydrogen atom, hydrogen atom), or a group of the formula —CH Y is oxo, (hydrogen atom, hydroxyl), (hydrogen atom, hydrogen atom), or a group of the formula N—NR R R R n is 1 or 2, wherein Y, R 10 and R 23 are optionally, together with the carbon atom they bind with, a saturated or unsaturated 5 or 6-membered heterocyclic group containing nitrogen atom, sulfur atom and/or oxygen atom, the heterocyclic group being optionally substituted by one or more group(s) selected from the group consisting of alkyl, hydroxy, alkyloxy, benzyl, a group of the formula —CH 2 Se(C 6 H 5 ), and alkyl substituted by one or more hydroxyl, or a pharmaceutically acceptable salt thereof.