Patent ID: 6221877
Filing Date: 2001-04-24
Classification: A61K,A61P,C07B,C07D

Abstract:
A compound of the formula: ##STR20##wherein:R.sup.1 is selected from the group consisting of: ##STR21##and a fused three-membered aryl or heteroaryl group; R.sup.2, R.sup.3 and R.sup.4 are independently selected from the group consisting of H, lower alkyl and halo; X is selected from the group consisting of --CH.sub.2 --O-- and --O--CH.sub.2 --; R.sup.5 is aryl; R.sup.6, R.sup.7 and R.sup.8 are independently selected from the group consisting of H and lower alkyl; R.sup.9 is lower alkyl and R.sup.10 is a cyclic aliphatic ring, or R.sup.9 and R.sup.10 can be taken together to form a cyclic aliphatic ring; and Y is selected from the group consisting of NH and O; or the pharmaceutically acceptable salts thereof.