Patent ID: 9193659
Filing Date: 2015-11-24
Classification: C07B,C07C,C25B

Abstract:
1. A process for the preparation of 3,5-disubstituted-2,4,6-triiodophenols of formula (2), which process comprises: (a) electrochemically generating I (b) iodinating 3,5-disubstituted-phenols of formula (1) in the presence of the I wherein R and R′ are, independently, selected from the group consisting of —COOH, —COOR 1 , —CONH 2 , —CONHR 1 and —CONR 2 R 3 ); wherein R 1 , R 2 and R 3 are, independently, a straight or branched C 1 -C 6 alkyl group which is optionally substituted by one or more groups selected from hydroxy, amino, sulphydryl, C 1 -C 6 alkoxy or carboxy, and/or optionally interrupted by one or more divalent groups selected from —NH—, —O—, —(C═O)—, —(C═O)O—, —O(C═O)—, —NH(C═O)—, —(C═O)NH—, —S(O)—or —S(O 2 )—groups.