Patent ID: 8354307
Filing Date: 2013-01-15
Classification: G01N,Y10T

Abstract:
1. A method for detecting a biomolecule electrically comprising: (a) providing an apparatus for electrical detection comprising a reaction chamber receiving a target sample, and a plurality of sensing electrodes located in the reaction chamber for detecting a biomolecule within the target sample; (b) first introducing a reference fluid having a high dielectric constant into the reaction chamber provided in step (a), and then first measuring an impedance value or a capacitance value between the sensing electrodes; (c) removing the reference fluid having a high dielectric constant from the reaction chamber from step (b) and introducing a reaction solution and the target sample into the reaction chamber; (d) reacting the target sample under the reaction solution in the reaction chamber as prepared in step (c); (e) removing the reaction solution from the reaction chamber after step (d); (f) secondly introducing said reference fluid having a high dielectric constant again into the reaction chamber as provided in step (a), and then secondly measuring an impedance value or a capacitance value between the sensing electrodes; and (g) comparing the impedance value or the capacitance value measured in the step (b) with the impedance value or the capacitance value measured in the step (f).