Patent ID: 8338382
Filing Date: 2012-12-25
Classification: A23G,A23L,A61K

Abstract:
1. A method of treating a disease associated with impaired mitochondrial function chosen from the group consisting of a nervous system disorder, a cardiovascular disorder and a musculoskeletal disorder, the nervous system disorder being chosen from the group consisting of Alzheimer's Disease, Huntington's Disease, Parkinson's Disease, spinocerebellar ataxia and a psychosis, the cardiovascular disorder being selected from the group consisting of atherosclerotic cardiovascular disease, cardiomyopathies and cardiac valvular disorders, and the musculoskeletal disorder consisting of mitochondrial myopathy, said method comprising administering to a patient in need thereof a pharmaceutical composition comprising: a sugar; a Krebs cycle intermediate, precursor of a Krebs cycle intermediate, salt thereof, or combination thereof; and a component selected from the group consisting of an unsaturated lipid, a soluble calcium compound, or a combination thereof.