Patent ID: 6086921
Filing Date: 2000-07-11
Classification: A61K,A61P

Abstract:
A method of suppressing bacterial growth comprising the step of supplying to a region for which said suppression is desired, an anti-bacterial agent comprising an antibacterial formulation selected from the group consisting of:(A) a mixture comprising (i) a non-pyrithione complexing agent having at least one thiol group, and (ii) bismuth or a bismuth containing compound;(B) a complex whose molecular structure includes (i) a non-pyrithione complexing agent having at least one thiol group, (ii) bismuth or a bismuth-containing compound; and (iii) a coordinate bond linking at least one sulfur atom of the thiol-containing complexing agent of subparagraph (B) (i) to the bismuth of subparagraph (B)(ii); and(C) a combination comprising the complex of paragraph (B) and at least one specie selected from the group consisting of (i) a thiol-containing complexing agent and (ii) bismuth or a bismuth-containing compound;wherein the molar ratio of bismuth to thiol-containing complexing agent in said anti-bacterial formulation is between 1:2 and 3:1.