Patent ID: 8741587
Filing Date: 2014-06-03
Classification: G01N

Abstract:
1. A method for assessing lung cancer in vitro in a patient, the method comprising: contacting, in vitro, a portion of a lung tissue sample obtained from the patient with an antibody having specific binding affinity for arginine-rich, mutated in early stage tumors (ARMET) protein and/or fragments thereof, thereby forming a complex of the antibody and ARMET protein and/or fragment thereof, the antibody having a detectable label; quantifying a signal from the detectable label of the antibody comprising the complex formed in said step of contacting, the signal being proportional to an ARMET concentration in the sample, whereby ARMET concentration in the sample is calculated; comparing the ARMET concentration in the sample to a control concentration; and diagnosing lung cancer in the patient if the ARMET concentration in the sample is greater than the control concentration.