Patent ID: 8673952
Filing Date: 2014-03-18
Classification: A61K,A61P,C07D

Abstract:
1. A compound selected from Formula I: and stereoisomers, geometric isomers, tautomers, or pharmaceutically acceptable salts thereof, wherein: Z Z Z Z where (i) X R R H, F, Cl, Br, I, —CN, —COR —C(═O)NR —C(═O)NR —C(═O)NR —C(═O)NR C C C C C C C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C where Z where alkyl, alkenyl, alkynyl, alkylene, carbocyclyl, heterocyclyl, aryl, and heteroaryl are optionally substituted with one or more groups independently selected from F, Cl, Br, I, R A is selected from C —C(═O)NR —C(═O)NR —C(═O)NR —C(═O)NR C C C C C C C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C —(C where alkyl, alkenyl, alkynyl, alkylene, carbocyclyl, heterocyclyl, aryl, and heteroaryl are optionally substituted with one or more groups independently selected from F, Cl, Br, I, R R R or R R or R R