Patent ID: 7973041
Filing Date: 2011-07-05
Classification: A61P,C07D

Abstract:
1. A method for treating a disease in a mammalian subject, wherein the disease is selected from the group consisting of arthritis and breast cancer, by administering to said mammal in need of such treatment, an effective amount of a compound according to the following formula: or pharmaceutically acceptable salt thereof, wherein P is -D-E-G-Q-L-T-X—Y, D is C(O); E is absent or is selected from the group consisting of C G is absent or is selected from the group consisting of O, NR Q is absent or is selected from the group consisting of a C L is absent or is selected from the group consisting of O, NR T is absent or is selected from the group consisting of C X is absent or is selected from the group consisting of O, NR Y is selected from the group consisting of H, a C provided that E, G, Q, L, T, X and Y do not combine to form a N—N, N—O, O—N, O—O, S(O) M is an aromatic heterocycle selected from the group consisting of pyridyl, quinolyl, and isoquinolyl and substituted with 0-5 R R R R R R and p at each occurrence is 0, 1, and 2.