Patent ID: 6723429
Filing Date: 2004-04-20
Classification: C08J,C08L,Y10T

Abstract:
A method for preparing spherical microparticles which have a smooth surface wherein the depth of irregularities on the particle surface is not more than 10% of the average diameter of the particle, and which comprise at least one water-insoluble linear polysaccharide, said method comprising the steps of(a) dissloving the at least one water-insoluble polysaccharide in a solvent or solvent mixture to form a solution, (b) introducing the solution into a precipitant or precipitant mixture to produce a polysaccharide-precipitant mixture and, where appropriate, cooling the polysaccharide-precipitant mixture, to produce microparticles, and (c) removing the microparticles, wherein at least one water-soluble cellulose derivative is used as a precipitation aid.