Patent ID: 6635434
Filing Date: 2003-10-21
Classification: C07K,G01N,Y10S

Abstract:
An immunogenic hapten-carrier complex comprising an immunogenic carrier and a compound of the following formula 1: wherein R2 is a linking unit to the carrier to form the hapten-carrier complex;R1 is selected from the group consisting of â€”C(&boxH;O)â€”N(R5)(R5), â€”N(R5)â€”C(&boxH;O)â€”OR5, â€”C(&boxH;O)â€”OR5, â€”N(R5)â€”C(&boxH;O)(R5), â€”N(R5)â€”C(&boxH;S)(R5), â€”C(&boxH;S)â€”N(R5)(R5), â€”N(R5)â€”C(&boxH;S)â€”N(R5)(R5),â€”N(R5)â€”C(&boxH;O)â€”N(R5)(R5), â€”Oâ€”C(&boxH;O)â€”R5, â€”C(&boxH;S)â€”OR5, â€”Oâ€”C(&boxH;S)â€”R5, â€”O5R5, â€”N(R5)(R5), â€”Sâ€”R5, â€”CH3â€”R5, â€”CN, and halogen; each R5 is independently selected from the group consisting of hydrogen, optionally substituted C1-4 alkyl, optionally substituted C2-5 alkenyl, optionally substituted C2-8 alkynyl, optionally substituted aryl, optionally substituted heteroaryl, and optionally substituted C3-C7 cycloalkyl; and X1 and X2 are the same or different and are each a halogen.