Patent ID: 8951765
Filing Date: 2015-02-10
Classification: C12M

Abstract:
1. An apparatus for cell separation, the apparatus comprising: a channel having an inlet and an outlet, the inlet configured to receive an initial carrier fluid containing at least a first cell; a flow surface extending between the inlet and the outlet of the channel, wherein the flow surface includes a patterned surface that includes one or more indentations fabricated to exhibit at least one characteristic of the first cell, wherein the patterned surface is configured to selectively capture at least the first cell and to permit the carrier fluid to flow therethrough, and wherein the patterned surface of the flow surface is at least partially coated with one or more photo-responsive azobenzene compound molecules having a first region configured to bind to a surface of the flow surface and having a second photo-responsive region configured to change conformation between a first more hydrophobic conformation and a second more hydrophilic conformation responsive to irradiation from an optical energy source,