Patent ID: 6048864
Filing Date: 2000-04-11
Classification: A61P,C07D

Abstract:
A substituted quinazoline of formula I, ##STR29## wherein R.sup.1 is C.sub.1-4 alkoxy optionally substituted by one or more fluorine atoms; each of R.sup.2 and R.sup.3 is H or C.sub.1-6 alkoxy (optionally substituted by one or more fluorine atoms, or by phenyl which may in turn be substituted by one or more fluorine atoms);R.sup.4 is a 6-membered heterocyclic ring containing a nitrogen atom, which ring is fused to a 6-membered heterocyclic ring containing a nitrogen atom, the ring system as a whole being optionally substituted by one or more substituents selected from OH, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, halogen and NHSO.sub.2 (C.sub.1-4 alkyl); provided that R.sup.2 and R.sup.3 are not both H; or a pharmaceutically acceptable salt thereof.