Patent ID: 9044402
Filing Date: 2015-06-02
Classification: A61K,A61P

Abstract:
1. An abuse-deterrent tablet formulated for oral administration of an opioid, the tablet consisting of a tablet composition and, optionally, a cosmetic coat, wherein: the tablet composition comprises: about 1-30% w/w of the opioid; and about 70-98% w/w of a polyethylene oxide (PEO) having an average molecular weight of from about 400,000 daltons to about 600,000 daltons; and the cosmetic coat, when present, covers at least a portion of the tablet composition, and dissolves within 30 minutes after contact with an aqueous media, wherein the tablet composition does not provide immediate release of the opioid even after the abuse-deterrent tablet is subjected to physical tampering selected from crushing, grinding, grating, cutting, or crisping, and wherein the tablet composition exhibits a viscosity of at least 170 mPa·s when measured by Viscosity Test #2, or a viscosity of at least 46 Pa·s when measured by Viscosity Test #1.