Patent ID: 8389688
Filing Date: 2013-03-05
Classification: A61K,A61P,C07K

Abstract:
1. A monoclonal humanized anti-CD22 antibody comprising a heavy chain variable region (“VH”) and a light chain variable region (“VL”), wherein (a) the heavy chain variable region comprises three complementarity determining regions (“CDRs”), VH CDR1, VH CDR2, and VH CDR3, and four framework regions (“FWs”), VH FW1, VH FW2, VH FW3, and VH FW4, in the order VH FW1, VH CDR1, VH FW2, VH CDR2, VH FW3, VH CDR3, and VH FW4, (b) the light chain variable region comprises three complementarity determining regions, VL CDR1, VL CDR2, and VL CDR3, and four framework regions, VL FW1, VL FW2, VL FW3, and VL FW4, in the order VL FW1, VL CDR1, VL FW2, VL CDR2, VL FW3, VL CDR3, and VL FW4;