Patent ID: 7627153
Filing Date: 2009-12-01
Classification: G03B

Abstract:
1. A method comprising: receiving initial image data corresponding to a first sample area of a biological sample; receiving initial positional information for the initial image data, the initial positional information indicative of an initial relative position of the first sample area with respect to an imaging system that obtained the data; using a positioner to reposition the first sample area with respect to the imaging system; receiving additional image data using the imaging system after repositioning the first sample area with respect to the imaging system; receiving additional positional information for the additional image data, the additional positional information indicative of a re-positioned relative position of the first sample area with respect to the imaging system; cross-correlating at least a portion of the initial image data and the additional image data using the associated initial image data, initial positional information, additional image data, and additional positional information; and determining an offset based on the cross-correlating.