Patent ID: 7687437
Filing Date: 2010-03-30
Classification: B01J,B82Y,G01N

Abstract:
1. A method for immobilizing a probe on a glass surface comprising the steps of: (a) reacting the glass surface with a solution at room temperature to provide immobilized reactive moieties, the solution comprising (3-isocyanatopropyl) triethoxysilane, an organic solvent, and an acid; and (b) reacting the immobilized reactive moieties with an amino-group containing molecule so as to immobilize said molecule on the glass surface, wherein the amino-group containing molecule further comprises one or more functional groups; (c) reacting the immobilized amino-group containing molecule on the surface with 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC) that reacts with a functional group of the immobilized amino-group containing molecule so as to produce second immobilized reactive moieties; and (d) reacting the second immobilized reactive moieties with a second molecule having a functional group capable of reacting with the second immobilized reactive moieties.