Patent ID: 8252947
Filing Date: 2012-08-28
Classification: A61K,A61P,C07B,C07J

Abstract:
1. Crystalline 17α-ethynylandrost-5-ene-3β,7β,17β-triol, wherein the crystalline 17α-ethynylandrost-5-ene-3β,7β,17β-triol is Form I having: (i) an X-ray powder diffraction pattern with peak positions of 10.38±0.1, 16.20±0.1 and 17.75±0.1 degrees 2-theta, or (ii) an X-ray powder diffraction pattern with peak positions of 10.38±0.1, 16.20±0.1 degrees 2-theta and a differential scanning calorimetry thermogram with a sharp endotherm at about 266° C., obtained using a temperature ramp of 10° C./min, or (iii) an X-ray powder diffraction pattern with peak positions of 10.38±0.1, 16.20±0.1 degrees 2-theta and one, two or three additional peak positions selected from the group consisting of 12.64±0.1, 15.08±0.1, 16.73±0.1, 28.92±0.1 degrees 2-theta, or (iv) a Raman spectroscopy spectrum with absorptions at peak positions of about 2106 and 1674 cm (v) a Raman spectroscopy spectrum with absorptions at peak positions of 2106 and 1674 cm (vi) a Raman spectroscopy spectrum substantially identical to that of (vii) a morphology essentially as shown in (viii) a combination of two or more of (i)-(vii) that have non-overlapping data.