Patent ID: 6319917
Filing Date: 2001-11-20
Classification: A61P,C07C,C07D

Abstract:
A compound of formula I ##STR12##whereinR is phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, lower alkyl, trifluoromethyl, hydroxy and lower alkoxy,R.sub.1 is hydrogen or lower alkyl,R.sub.2 is hydrogen, lower alkyl or phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, lower alkyl, trifluoromethyl, hydroxy and lower alkoxy,R.sub.3 is phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, lower alkyl, trifluoromethyl, hydroxy and lower alkoxy; or is naphthyl, 1H-indol-3-yl or 1-lower alkyl-indol-3-yl,R.sub.4 ' and R.sub.4 "" are each independently of the other hydrogen or lower alkyl, at least one of the radicals R.sub.4 ' and R.sub.4 "" being hydrogen, andR.sub.5 is C.sub.3 -C.sub.8 cycloalkyl, D-azacycloheptan-2-on-3-yl or L-azacycloheptan-2-on-3-yl;or a salt thereof.