Patent ID: 9163221
Filing Date: 2015-10-20
Classification: C07C,C07K,C10G,C11D,C12N,C12P,Y02P

Abstract:
1. A fatty alcohol forming acyl-CoA reductase (FAR) variant that has at least 90% sequence identity to SEQ ID NO:5, wherein the variant comprises a substitution at one or more positions selected from position 512, position 2, position 508, position 511, position 503, position 434, position 501, position 459, position 135, and position 139, wherein the position is numbered with reference to SEQ ID NO:5, and wherein a cell in which the FAR variant is expressed produces more fatty alcohol than a corresponding cell of the same type in which the wild-type FAR from which the FAR variant is derived is expressed, wherein the cell is a yeast cell or a bacterial cell.