Patent ID: 7074938
Filing Date: 2006-07-11
Classification: A61K,A61Q

Abstract:
1. A method for making a Soritin compound or having the following structural formula (A): or a Soritin composition comprising the Soritin compound which comprises reacting a compound of the structural formula (1): with a metallic base having the formula M {circle around (+)} B {circle around (−)} and then adding L-X, wherein L is a leaving group and X is, or is convertible to, —H, —OH, halogen, —COOH, —COOR, C 1 –C 8 alkyl, cycloalkyl, C 1 –C 8 alkoxyl, mesyl, tosyl, mesyloxy, tosyloxy, arylsulfonyl, arylsulfonyloxy, —OCOR, or NZ 1 Z 2 (wherein Z 1 and Z 2 can be the same or different) to give the Soritin compound or the Soritin composition, wherein R Z R is C X is —H, —OH, halogen, —COOH, —COOR, C M is a suitable metal ion; and B is a suitable base.