Patent ID: 8148535
Filing Date: 2012-04-03
Classification: A61P,C07D

Abstract:
1. A compound of formula I, or a pharmaceutically acceptable salt, or an optical isomer thereof, wherein: A is B is a heteroaryl ring, wherein the point of attachment to the heteroaryl ring is a carbon atom or a nitrogen atom, and wherein the heteroaryl ring is said heteroaryl ring is unsubstituted, mono-substituted with R C is a phenyl ring, wherein said phenyl ring is unsubstituted, mono-substituted with R D is —NH-A X is H, F, C Y is selected from the group consisting of H, F, C Z is selected from the group consisting of H, OR R R R R m is independently 0, 1 or 2; and n, in each instance in which it occurs, is independently selected from 0, 1, 2, 3, 4, 5 or 6.