Patent ID: 8282926
Filing Date: 2012-10-09
Classification: A61P,C07K

Abstract:
1. An isolated antibody that binds specifically to an epitope present in a peptide consisting of the contiguous sequence E-W-Q-K-E-G-L-V-T-L-W-L (SEQ ID NO: 1) or the contiguous sequence E-W-Q-R-E-G-L-V-T-L-W-L (SEQ ID NO: 30), wherein the peptide closely mimics a conformational epitope of CCR5 that is involved in human immunodeficiency virus (HIV), simian-human immunodeficiency virus (SHIV) or simian immunodeficiency virus (SIV) infection and which is recognized by mAb 2D7, wherein the antibody is not mAb 2D7.