Patent ID: 8470820
Filing Date: 2013-06-25
Classification: A61P,C07D

Abstract:
1. A compound of formula (I) wherein A R R R Y is 5-membered heteroaryl selected from the group consisting of: wherein said heteroaryl is optionally substituted by one substituent selected from the group consisting of lower alkyl, which is optionally substituted by 1 to 3 substituents selected from the group consisting of aryl, cycloalkyl, heterocyclyl, lower alkoxy, hydroxyl, halogen, amino optionally substituted by one or two lower alkyl, COOH, COO-lower alkyl, oxo, cyano and heteroaryl optionally substituted by 1 to 3 substituents selected from the group consisting of hydroxyl, halogen, lower alkyl, lower alkoxy, lower hydroxyalkyl, lower haloalkyl, lower alkoxy lower alkyl, acetyl, cyano and amino optionally substituted by 1 or 2 lower alkyl or lower alkoxy lower alkyl, cycloalkyl optionally substituted by 1 to 3 substituents selected from the group consisting of hydroxyl, halogen, lower alkyl, lower alkoxy, lower hydroxyalkyl, lower haloalkyl, lower alkoxy lower alkyl, acetyl, cyano and amino optionally substituted by 1 or 2 lower alkyl or lower alkoxy lower alkyl, and heterocyclyl optionally substituted by 1 to 3 substituents selected from the group consisting of hydroxyl, halogen, lower alkyl, lower alkoxy, lower hydroxyalkyl, lower haloalkyl, lower alkoxy lower alkyl, acetyl, cyano and amino optionally substituted by 1 or 2 lower alkyl or lower alkoxy lower alkyl; and R or a pharmaceutically acceptable salt thereof.