Patent ID: 9086415
Filing Date: 2015-07-21
Classification: C07K,G01N

Abstract:
1. A method for evaluating the progression of myelodysplastic syndrome (MDS) in a subject, said method comprising: (a) obtaining a first sample of serum from the subject; (b) obtaining a second sample of serum from the subject later in time; (c) measuring the amount of antibody in said first and second samples that is able to bind to an antigen consisting of amino acids 1-294 of SEQ ID NO: 5; (d) comparing the amount of said antibody in said first sample to the amount of said antibody in said second sample; and (e) making a diagnosis that the MDS in said subject is not progressing when the amount of said antibody in said second sample is less than the amount of said antibody in said first sample, or making a diagnosis that the MDS in said subject is progressing when the amount of said antibody in said second sample is the same as or more than the amount of said antibody in said first sample.