Patent ID: 6187955
Filing Date: 2001-02-13
Classification: A61K,A61Q,C07C,C07D,C07F,Y10S

Abstract:
A guanidine derivative represented by the following formula (1) or an acid addition salt thereof ##STR7##wherein A and B may be the same or different from each other and each represents an alkylene group having 2 to 8 carbon atoms, D represents a single bond, --CO-- or an alkylene group having 1 to 6 carbon atoms, E represents a hydrogen atom, a lower alkyl group, an aralkyl group or an aryl group which may have a substituent group, m is an integer of 1 to 6, n is an integer of 0 to 6 and R.sup.1 represents a hydrogen atom, a lower alkyl group or --(AO).sub.m --(BO).sub.n --D--E, with the provisos thata. R.sup.1 is not hydrogen atom nor a methyl group when A is a straight chain alkylene group, m=1 and n=0, thatb. --(AO).sub.m --(BO).sub.n --D--E is not a hydroxyethyl group when R.sup.1 is a hydrogen atom, a lower alkyl group or a hydroxyethyl group, and thatc. --(AO).sub.m --(BO).sub.n --D--E is not a lower alkoxyethyl group when R.sup.1 is hydrogen atom.