Patent ID: 7786307
Filing Date: 2010-08-31
Classification: A61P,C07C,C07D

Abstract:
1. A compound selected from the group consisting of N-(4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-piperidin-1-ylhexyl)-2-(3-methoxypropoxy)benzamide dihydrochloride N-(4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-piperidin-1-ylhexyl)-2-(4-methoxy-butoxy)benzamide dihydrochloride, N-(4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-morpholin-4-ylhexyl)-2-(4-methoxy-butoxy)benzamide dihydrochloride, N-[4(S)-amino-6-(9-azabicyclo [3.3.1]non-9-yl)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-[4(S)-amino-6-(cis-2,6-dimethylpiperidin-1-yl)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-[4(S)-amino-6-(3-methylpiperidin-1-yl)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-[4(S)-amino-6-(4-methylpiperidin-1-yl)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-(4(S)-amino-6-sec-(S)-butylamino-5(S)-hydroxy-2(S)-isopropylhexyl)-2-(4-methoxy-butoxy)benzamide dihydrochloride, N-(4(S)-amino-6-tert-butylamino-5(S)-hydroxy-(S)-isopropylhexyl)-2-(4-methoxy-butoxy)benzamide dihydrochloride, N-(4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-isopropylaminohexyl)-2-(4-methoxy-butoxy)benzamide dihydrochloride, N-(4(S)-amino-6-sec-(R)-butylamino-5(S)-hydroxy-2(S)-isopropylhexyl)-2-(4-methoxy-butoxy)benzamide dihydrochloride, N-[4(S)-amino-6-(cyclopropylmethylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-[4(S)-amino-6-(1,1-dimethylpropylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-(4(S)-amino-6-ethylamino-5(S)-hydroxy-2(S)-isopropylhexyl)-2-(4-methoxybutoxy)-benzamide dihydrochloride, N-(4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-propylaminohexyl)-2-(4-methoxy-butoxy)benzamide dihydrochloride, N-[4(S)-amino-6-(1-ethylpropylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxy-butoxy)benzamide dihydrochloride, N-(4(S)-amino-6-cyclopentylamino-5(S)-hydroxy-2(S)-isopropylhexyl)-2-(4-methoxy-butoxy)benzamide dihydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2(R)-methylpiperidin-1-yl)hexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2(S)-methylpiperidin-1-yl)hexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-(4(S)-amino-5(S)-hydroxy-6-isobutylamino-2(S)-isopropylhexyl)-2-(4-methoxy-butoxy)benzamide dihydrochloride, N-[4(S)-amino-6-(1-ethyl-1-methylpropylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-(4(S)-amino-6-cyclopropylamino-5(S)-hydroxy-2(S)-isopropylhexyl)-2-(4-methoxy-butoxy)benzamide dihydrochloride, N-(4(S)-amino-6-azepan-1-yl-5(S)-hydroxy-2(S)-isopropylhexyl)-2-(4-methoxybutoxy)-benzamide dihydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(1(S)-methylpentylamino)hexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(1(R)-methylpentylamino)hexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-(4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-pyrrolidin-1-ylhexyl)-2-(4-methoxy-butoxy)benzamide dihydrochloride, N-(4(S)-amino-6-benzylamino-5(S)-hydroxy-2(S)-isopropylhexyl)-2-(4-methoxy-butoxy)benzamide dihydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2(R)-methoxymethylpyrrolidin-1-yl)hexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-6-(1-carbamoylethylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-[6-(3(S)-acetylaminopyrrolidin-1-yl)-4(S)-amino-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-Amino-6-(2,2-dimethylpropionylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(3-methoxypropoxy)benzamide hydrochloride N-{4(S)-Amino-5(S)-hydroxy-2(S)-isopropyl-6-[2-methyl-2-(tetrahydropyran-4-yl)propionyl-amino]hexyl}-2-(3-methoxypropoxy)benzamide hydrochloride N-[4(S)amino-6-(2,2-dimethylpropionylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-{4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-[2-methyl-2-(tetrahydropyran-4-yl)-propionylamino]hexyl}-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-6-(2-cyclohexyl-2-methylpropionylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-{4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-[(1-phenylcyclobutanecarbonyl)amino]hexyl}-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)amino-6-(2,2-dimethylhexanoylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-(4(S)-amino-6-{[1-(4-chlorophenyl)cyclobutanecarbonyl]amino}-5(S)-hydroxy-2(S)-isopropylhexyl)-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-methyl-2-m-tolylpropionylamino)hexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-6-(2-cyclopentyl-2-methylpropionylamino)-S(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-methyl-2-morpholin-4-ylpropionyl-amino)hexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-{4(S)-amino-6-[2-(3-fluorophenyl)-2-methylpropionylamino]-5(S)-hydroxy-2(S)-isopropylhexyl}-2-(4-methoxybutoxy)benzamide hydrochloride, N-{4(S)-amino-6-[(1-cyclohexylcyclobutanecarbonyl)amino]-5(S)-hydroxy-2(S)-isopropylhexyl}-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-methyl-2-pyridin-3-ylpropionylamino)hexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-[4(S)-amino-6-(3-chloro-2,2-dimethylpropionylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[6-(2-acetylamino-2-methylpropionylamino)-4(S)-amino-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-{4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-[(1-trifluoromethylcyclobutanecarbonyl)-amino]hexyl}-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-6-(2-cyclohexyloxy-2-methylpropionylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)hydroxy-2(S)-isopropyl-6-(2-methoxy-2-methylpropionylamino)hexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-methyl-2-piperidin-1-ylpropionyl-amino)hexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-{4-amino-5-hydroxy-2-isopropyl-6-[(1-methylcyclohexanecarbonyl)amino]hexyl}-2-(4-methoxybutoxy)benzamide hydrochloride, N-{4(S)-amino-5(S)-hydroxy-6-[2-(1H-indol-3-yl)-2-methylpropionylamino]-2(S)-isopropylhexyl}-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-methoxypropionylamino)hexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-(3(S)-amino-2(S)-hydroxy-5(S)-{[2-(4-methoxybutoxy)benzoylamino]methyl}-6-methylheptyl)adamantane-1-carboxamide hydrochloride, N-{4(S)-amino-6-[(2,2-dimethylpropionyl)hydroxyamino]-5(S)-hydroxy-2(S)-isopropylhexyl}-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-6-(3,3-dimethylureido)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-(4(S)-amino-6-benzoylamino-5(S)-hydroxy-2(S)-isopropylhexyl)-2-(4-methoxy-butoxy)benzamide hydrochloride, N-[4(S)-amino-6-(formylisopropylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[6-(acetylmethylamino)-4(S)-amino-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxy-butoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-methyl-2-pyridin-2-ylpropionylamino)hexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-methyl-2-piperidin-4-ylpropionyl-amino)hexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(3,3,3-trifluoro-2(R)-methoxy-2-phenyl-propionylamino)hexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[6-(N-acetylhydrazino)-4(S)-amino-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxy-butoxy)benzamide dihydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2(R)-methoxy-3-phenylpropionylamino)hexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-6-(3-cyclohexyl-2(R)-methoxypropionylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-methyl-2-piperidin-3(R)-ylpropionyl-amino)hexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-methyl-2-piperidin-3(S)-ylpropionyl-amino)hexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-{4(S)-amino-5(S)-hydroxy-6-[2-(1H-imidazol-4-yl)-2-methylpropionylamino]-2(S)-isopropylhexyl}-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-6-(2,2-dimethyl-4-methylaminobutyrylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-{4(S)-amino-5(S)-hydroxy-6-[(2(S)-hydroxy-(S)-cyclopentanecarbonyl)amino]-2(S)-isopropylhexyl}-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-methyl-2-piperidin-2(S)-ylpropionyl-amino)hexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-methyl-2-piperidin-2(R)-ylpropionyl-amino)hexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-methyl-2-(1,2-dihydrospiro[3H-indole-3,4′-piperidin]-1′-yl)propionylamino)hexyl]-2-(4-methoxybutoxy)benzamide dihydrochloride N-{4(S)-amino-5(S)-hydroxy-6-[2-(cis-4-hydroxycyclohex-1-yl)-2-methylpropionylamino]-2(S)-isopropylhexyl}-2-(4-methoxybutoxy)benzamide hydrochloride, N-{4(S)-amino-5(S)-hydroxy-6-[2-(trans-4-hydroxycyclohex-1-yl)-2-methylpropionylamino]-2(S)-isopropylhexyl}-2-(4-methoxybutoxy)benzamide hydrochloride, N-{4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-[2-(cis-4-methoxycyclohex-1-yl)-2-methylpropionylamino]hexyl}-2-(4-methoxybutoxy)benzamide hydrochloride, N-{4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-[2-(trans-4-methoxycyclohex-1-yl)-2-methylpropionylamino]hexyl}-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-6-(2-cyclohexyl-2(R)-methoxyacetylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2(R)-methoxy-2-phenylacetylamino)hexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2(R)-methoxy-3,3-dimethylbutyryl-amino)hexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(3,3,3-trifluoro-2-methoxy-2-trifluoromethylpropionylamino)hexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(3,3,3-trifluoro-2(R)-methoxy-2-methyl-propionylamino)hexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(3,3,3-trifluoro-2(S)-methoxy-2-methyl-propionylamino)hexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-6-(2-cyclohexyl-3,3,3-trifluoro-2(R)-methoxypropionylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2(R)-methoxy-2-phenylpropionylamino)hexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-6-(2-cyclohexyl-2(R)-methoxypropionylamino)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-{4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-[(1-methoxycyclopentanecarbonyl)-amino]hexyl}-2-(4-methoxybutoxy)benzamide hydrochloride, N-{4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-[(1-methoxycyclohexanecarbonyl)amino]hexyl}-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-Amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-methyl-2-piperidin-3(R,S)-yl-N-{4(S)-Amino-5(S)-hydroxy-2(S)-isopropyl-6-[2-methyl-2-(1-methyl-piperidin-3(R,S)-yl)-propionylamino]-hexyl}-2-(4-methoxy-butoxy)-benzamide dihydrochloride, N-[4(S)-Amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-methyl-2-piperidin-2(R,S)-yl-propionylamino)-hexyl]-2-(4-methoxy-butoxy)-benzamide dihydrochloride, N-{4(S)-Amino-5(S)-hydroxy-2(S)-isopropyl-6-[2-methyl-2-(1-methyl-piperidin-2(R,S)-yl)-propionylamino]-hexyl}-2-(4-methoxy-butoxy)-benzamide dihydrochloride, N-{4(S)-Amino-5(S)-hydroxy-6-[2(R,S)-(trans-2-hydroxy-cyclohexyl)-2-methyl-propionylamino]-2(S)-isopropyl-hexyl}-2-(4-methoxy-butoxy)-benzamide hydrochloride, N-{4(S)-Amino-5(S)-hydroxy-6-[2-(3(S)-hydroxy-cyclohex-1(R)-yl)-2-methyl-propionylamino]-2(S)-isopropyl-hexyl}-2-(4-methoxy-butoxy)-benzamide hydrochloride, N-[4(S)-Amino-5(S)-hydroxy-6-(2-imidazol-1-yl-2-methyl-propionylamino)-2(S)-isopropyl-hexyl]-2-(4-methoxy-butoxy)-benzamide dihydrochloride, N-[4(S)-Amino-6-(2-cyano-2,2-dimethyl-acetylamino)-5(S)-hydroxy-2(S)-isopropyl-hexyl]-2-(4-methoxy-butoxy)-benzamide hydrochloride, N-{6-[trans-2-(4-Acetylamino-cyclohexyl)-2-methyl-propionylamino]-4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-hexyl}-2-(4-methoxy-butoxy)-benzamide hydrochloride, N-{6-[2-(3(S)-Acetylamino-cyclohex-1(R)-yl)-2-methyl-propionylamino]-4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-hexyl}-2-(4-methoxy-butoxy)-benzamide hydrochloride, N-[4(S)-Amino-6-(2,2-difluoro-2-phenyl-acetylamino)-5(S)-hydroxy-2(S)-isopropyl-hexyl]-2-(4-methoxy-butoxy)-benzamide hydrochloride, N-[4(S)-Amino-6-(2-cyclohexyl-2,2-difluoro-acetylamino)-5(S)-hydroxy-2(S)-isopropyl-hexyl]-2-(4-methoxy-butoxy)-benzamide hydrochloride, N-{4(S)-Amino-6-[2,2-difluoro-2-(tetrahydro-pyran-4-yl)-acetylamino]-5(S)-hydroxy-2(S)-isopropyl-hexyl}2-(4-methoxy-butoxy)-benzamide hydrochloride, N-[4(S)-Amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-oxopiperidin-1-yl)hexyl]-2-(3-methoxy-propoxy)benzamide hydrochloride N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-oxopiperidin-1-yl)hexyl]-2-(4-methoxy-butoxy)benzamide hydrochloride, N-[4(S)-amino-6-(3,3-dimethyl-2-oxopyrrolidin-1-yl)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-oxoazepan-1-yl)hexyl]-2-(4-methoxy-butoxy)benzamide hydrochloride, N-[4(S)-amino-6-(3,3-dimethyl-2-oxoazepan-1-yl)-5(S)-hydroxy-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-6-(4-hydroxy-2-oxopyrrolidin-1-yl)-2(S)-isopropylhexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-oxotetrahydropyrimidin-1-yl)hexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-Amino-5(S)-hydroxy-2(S)-isopropyl-6-(propane-2-sulphonylamino)hexyl]-2-(3-methoxypropoxy)benzamide hydrochloride N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(propane-2-sulphonylamino)hexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-(4(S)-amino-6-cyclopropanesulphonylamino-5(S)-hydroxy-2(S)-isopropylhexyl)-2-(4-methoxybutoxy)benzamide hydrochloride, N-(4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-phenylmethanesulphonylaminohexyl)-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-amino-5(S)-hydroxy-2(S)-isopropyl-6-(thiophene-2-sulphonylamino)hexyl]-2-(4-methoxybutoxy)benzamide hydrochloride, N-(4(S)-amino-6-benzenesulphonylamino-5(S)-hydroxy-2(S)-isopropylhexyl)-2-(4-methoxybutoxy)benzamide hydrochloride, N-[4(S)-Amino-5(S)-hydroxy-2(S)-isopropyl-6-(2-methyl-propane-2-sulfonylamino)-hexyl]-2-(4-methoxy-butoxy)-benzamide hydrochloride and N-[4(S)-Amino-6-(2-cyclohexyl-propane-2-sulfonylamino)-5(S)-hydroxy-2(S)-isopropyl-hexyl]-2-(4-methoxy-butoxy)-benzamide hydrochloride.