Patent ID: 8048676
Filing Date: 2011-11-01
Classification: A61K,C07K,C12Q,G01N,Y10S

Abstract:
1. A kit for detecting the presence of multiple oncogenic human papilloma virus (HPV) E6 polypeptides including HPV strains 16, 18 and 33 in a patient sample, said kit comprising: a first and a second binding partner for an oncogenic HPV E6 polypeptide, wherein said first binding partner is a PDZ domain polypeptide that is less than 1000 amino acids in length and comprises the amino acid sequence of MAGI-1 PDZ domain 2; and binding of said oncogenic HPV E6 polypeptide to said PDZ domain polypeptide indicates the presence of an oncogenic HPV E6 polypeptide in said sample.