Patent ID: 9205035
Filing Date: 2015-12-08
Classification: A61K,A61L,A61P,A61Q,C01B

Abstract:
1. A method for the formation of substantially spherical particles of an ion substituted calcium phosphate compound, comprising the steps of: providing an aqueous solution comprising calcium, magnesium and phosphate ions, and one or more of sodium, potassium, chloride, carbonate or sulphate ions, wherein the concentration of said ions are: calcium ions in the range of 0.01-25×10 and when present, sodium ions in the range of 0.01-1420×10 wherein the solution has an initial pH in the range of 2.0 to 10.0, and wherein the solution further comprises at least one of substitution ions Sr precipitating the particles by a self-organized process in a solution according to a, b, c, d or e, wherein: a. is a static process wherein the solution comprises Sr b. is a stirring process wherein the solution comprises Sr c. is a hydrothermal process wherein the solution comprises Sr d. is a hydrothermal process wherein the solution comprises F e. is a hydrothermal process wherein the solution comprises Si