Patent ID: 8501788
Filing Date: 2013-08-06
Classification: A61K

Abstract:
1. A process for preparing a pharmaceutical dosage form comprising flunixin or a flunixin analog, wherein the process comprises: (a) obtaining a pharmaceutical composition comprising flunixin or a flunixin analog, and at least one auxiliary substance; (b) recovering the flunixin or a flunixin analog from the pharmaceutical composition by preferential dissolution; and (c) formulating the flunixin or a flunixin analog into a pharmaceutical dosage form comprising the flunixin or a flunixin analog, and at least one auxiliary substance; wherein the flunixin or the flunixin analog is purified to a purity of at least 90% and wherein the recovery of the flunixin comprises a preferencial dissolution of at least one auxiliary substance by a solvent relative to flunixin or the flunixin analog and wherein the solvent is selected from the group consisting of water, methanol, ethanol, isopropanol, propanol, butanol, t-butanol, pentanol, neo-pentanol, methylene chloride, chloroform, carbon tetrachloride, 1,2-dichloroethane, ethyl acetate, acetone, tetrahydrofuran, ether, dimethylsulfoxide, N,N-dimethylformamide, trifluoroethanol, and combinations thereof.