Patent ID: 6291692
Filing Date: 2001-09-18
Classification: C07D

Abstract:
A tetracylic taxane having the formula ##STR29##whereinR.sub.1 is H, --OH, protected hydroxy, or --OCOR.sub.8,R.sub.4 is --OH or protected hydroxy,R.sub.5 is H or R.sub.9 CO--,R.sub.6 is H or R.sub.10 OCO--,R.sub.7 is H or a hydroxy protecting group, andR.sub.8, R.sub.9, and R.sub.10 are independently H, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 alkenyl, C.sub.2 -C.sub.6 alkynyl, moncyclic aryl, or monocyclic heteroaryl.