Patent ID: 8575199
Filing Date: 2013-11-05
Classification: A61P,C07D

Abstract:
1. A compound of formula (IA″): or a pharmaceutically acceptable salt, stereoisomer, or tautomer thereof, wherein X is O; W is C; the dashed line denotes the presence or absence of a bond, and when the dashed line is present as a bond to provide one bond of a double bond then R R each R Ar Ar c is the integer 0, 1, or 2; Y wherein no more than one of Y R E is ═O, ═S, ═CH(C R each R wherein Q is Z Z each Z provided that at least one R each R bridge, or a bridge; R R each R each R each R each R each R each R each R each halo is independently —F, —Cl, —Br, or —I; n is the integer 1, 2, or 3; each b is independently 1 or 2; q is the integer 0, 1, 2, 3, or 4; r is the integer 0, 1, 2, 3, 4, 5, or 6; s is the integer 0, 1, 2, 3, 4, or 5; t is the integer 0, 1, 2, or 3; and m is the integer 0, 1, or 2.