Patent ID: 8501483
Filing Date: 2013-08-06
Classification: G01N

Abstract:
1. A method for treating breast cancer in a breast cancer patient identified as having a positive recurrence status comprising a step of treating the patient with a second line therapy comprising a step of (a) identifying the breast cancer patient having positive recurrence status by assaying a biological sample from the patient for a level of a biomarker selected from S100β or HOXC11, wherein positive detection of one or both of the markers is indicative of a positive recurrence status, wherein when the biomarker is HOXC11 positive detection means an Allred score from 3-8 for nuclear HOXC11, and when the biomarker is S100β positive detection means a level of serum S100β greater than 200pg/ml or an Allred score from 3-8 for tumor cells, and (b) administering to the breast cancer patient having a positive recurrence status a second line of therapy.