Patent ID: 7867757
Filing Date: 2011-01-11
Classification: B01J,B01L

Abstract:
1. A microfabricated chamber system for carrying out a nucleic acid sequence amplification and detection process on a nucleic acid sample, the system comprising an inlet port and/or an outlet port characterized in that the system further comprises an array of variable volume chamber in fluid communication with said port(s), wherein altering the volume of the variable volume chamber effects and/or restricts flow of a fluid sample to and/or from said port(s), and wherein a variable volume chamber comprises a chamber having at least one wall formed from a flexible material, wherein depression and/or extension of the said at least one wall alters the volume of the variable volume chamber, and wherein the system further comprises an actuator comprising an array of depression members, said array being arranged to be substantially in register with the array of variable volume chambers, wherein, in use, a depression member is brought into contact with said at least one wall to cause depression thereof.