Patent ID: 7901887
Filing Date: 2011-03-08
Classification: G01N,G06K,G06T

Abstract:
1. A method in automated microscopy comprising: receiving a plurality of slides comprising serially microtomed slices of a specimen wherein adjacent microtome slices are treated such that a first microtome slice is treated with a bright field detectable stain, while every adjacent second microtome slice is treated with a fluorescence in situ hybridization (FISH) probe under hybridizing conditions; producing a bright field microscopy image of said first microtome slice; accepting input that identifies the regions of interest in said bright field microscopy image; automatically mapping said regions of interest in said bright field microscopy image onto said adjacent second microtome slice; automatically microscopically examining said regions of interest of said adjacent second microtome slice characterizing fluorescence signals of said hybridized FISH probe detected in said mapped regions of interest; outputting results with respect to said hybridized FISH probe detected in said mapped regions of interest.