Patent ID: 6635435
Filing Date: 2003-10-21
Classification: C07C,C09B,C12Q

Abstract:
A fluorogenic substrate molecule having the following characteristics:(a) said molecule re-emits at least about 70% of the energy of the incident radiation that is used to excite the molecule; (b) the molecule emits radiation at a wavelength that is at least about 25 nm from the wavelength of radiation used to excite the molecule; and (c) the molecule is soluble and stable in water; and wherein said molecule has the following structure: and salts thereof, wherein:R1 is selected from the group consisting of phosphate, sulfonamide, â€”O-galactoside, â€”O-glucoside, â€”O-glucuronide, and N-acetylglucosaminide; and R2, R3, and R4, can be the same or different, and are selected from the group consisting of SO3 and halides; provided that at least one of R2, R3, or R4 is a halide.