Patent ID: 7973024
Filing Date: 2011-07-05
Classification: A61P,C07C

Abstract:
1. A method for treating diseases which benefit from an inhibition of the catabolism of 1α,25-dihydroxy vitamin D 3 , or analogs thereof, said disease selected from the group consisting of breast cancer, lung cancer, prostate cancer, colon cancer, colorectal cancer, kidney cancer, head and neck cancer, pancreatic cancer, Kaposi's sarcoma, leukemia, psoriasis, hyperparathyroidism, secondary hyperparathyroidism and osteoporosis, comprising administering to a cell or animal in need thereof, an effective amount of a compound selected from a compound of Formula I, and pharmaceutically acceptable salts and prodrugs thereof: wherein R R each R R each R R R R provided that when there is a double bond between C22 and C23, there is only one R