Patent ID: 8812248
Filing Date: 2014-08-19
Classification: G06F,G16B

Abstract:
1. A non-transitory computer-readable medium encoded with instructions, executable by a processor, for determining a genotype for a genomic locus in a biological sample, the instructions comprising instructions for: receiving a data set for a genotyping assay, wherein the data set comprises a data point for each sample in a plurality of biological samples; determining an angle for each data point in the data set, wherein a vertex for each angle contains a defined origin; performing an optimal angle configuration search for the data set; said optimal angle configuration search comprising a best fit of the angles determined for each data point in the data set to an angle configuration in a plurality of angle configurations in a data base; and assigning a final genotype classification to each sample in the plurality of biological samples based on the fit of the data set to a best-fit angle configuration, wherein each angle of the best-fit angle configuration is discretely associated with a finite number of allelic combinations defining a genotype classification.