Patent ID: 6592877
Filing Date: 2003-07-15
Classification: A61K,A61P,C07K

Abstract:
An isolated fusion protein comprising four polypleptides, whereinthe first polypeptide comprises a M. tuberculosis antigen having an amino acid sequence of TbRa3 (SEQ ID NO:77) or an immunogenic portion thereof; the second polypeptide comprises a M. tuberculosis antigen having an amino acid sequence of Tb38-1 (SEQ ID NO:88) or an immunogenic portion thereof; the third polypeptide comprises a M. tuberculosis antigen having an amino acid sequence of TbH4 (SEQ ID NO:89) or an immunogenic portion thereof; and the fourth polypeptide comprises a M. tuberculosis antigen having an amino acid sequence of 38 kD (SEQ ID NO:155) or an immunogenic portion thereof.