Patent ID: 6013449
Filing Date: 2000-01-11
Classification: C12Q

Abstract:
A method of analyzing a nucleic acid in a target sample, comprising:(a) hybridizing a first-labelled control sample comprising a homozygous reference allele, and a second-labelled target sample comprising the homozygous reference allele, or variant alleles differing from the reference allele at a locus, or one variant allele differing from the reference allele at the locus and one reference allele, to at least one set of probes spanning the locus and complementary to the reference allele, wherein the first and second labels are different;(b) measuring the intensity of first and second label bound to each probe in the set;(c) based on the measuring step indicating the presence of one variant allele and one reference allele, or the presence of two variant alleles in the target sample.