Patent ID: 6384085
Filing Date: 2002-05-07
Classification: A61K,A61P

Abstract:
An antioxidant containing a compound represented by Formula I which is obtained from Ecklonia Cava by a process comprising the steps of:a) extracting the Ecklonia Cava one or more times using at least one solvent selected from the group consisting of methanol, ethanol, ethyl acetate, acetonitrile, acetone, and an aqueous solution thereof; b) fractionating the extract by using an aqueous 10 to 90% methanol solution as a polar layer, and a solvent selected from the group consisting of linear hydrocarbons, cyclic hydrocarbons, aromatic solvents, or mixtures thereof, as a nonpolar layer; c) fractionating the aqueous methanol layer obtained in step b) by using an aqueous 10 to 60% methanol solution as a polar layer and one or more ethers as a nonpolar layer; d) fractionating the aqueous methanol layer obtained in step c) by using an aqueous 10 to 60% methanol solution as a polar layer and chloroform, dichloromethane, or a mixture thereof as a nonpolar layer; and e) purifying the aqueous methanol layer obtained in step d) by chromatography.