Patent ID: 8956602
Filing Date: 2015-02-17
Classification: A61K,A61P

Abstract:
1. A pharmaceutical formulation which (a) comprises (i) a side-chain crystalline (CYSC) polymer which has a polymer backbone and (ii) a single drug, the drug being associated with the CYSC polymer, (b) is free from oil, and (c) is in a dosage form which can be administered by ingestion, injection, subcutaneous implantation, intramuscular administration, intrathecal administration or inhalation, wherein the CYSC polymer, (A) comprises a plurality of moieties which (B) comprises a plurality of repeating units of the formula (C) has a crystalline melting temperature, Tp, of 22 to 70° C., and an onset of melting point, To, such that (Tp−To) is less than 15° C.; (D) has a heat of fusion of least 5 J/g which results from the association of the Cy moieties; (E) is not cross-linked, and (F) has a number average molecular weight, Mn, of 1000 to 20,000 Daltons.