Patent ID: 8003662
Filing Date: 2011-08-23
Classification: A61P,C07D

Abstract:
1. A compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein: X is O; Z R R R wherein the wavy line indicates the attachment to X, and each R 4 is independent of the other; R wherein R 14a is null and R 10a and R 15a together with the atoms to which they are attached form an optionally substituted heteroaryl ring having a ring nitrogen atom and optionally having one or more additional heteroatoms selected from N, O and S; R R R or R R R Y is independently O or S; t is 1, 2, 3, 4, 5 or 6; and n and m are independently 0, 1, 2, 3, 4, 5 or 6.