Patent ID: 6110717
Filing Date: 2000-08-29
Classification: C12N

Abstract:
An isolated polynucleotide comprising a polynucleotide sequence having at least 70% identity to a nucleotide sequence encoding a polypeptide comprising the amino acid sequence set forth in SEQ ID NO:2 which may include up to n.sub.a nucleic acid alterations over the entire length of SEQ ID NO: 1, wherein n.sub.a is represents the maximum number of such alterations and is calculated by the formulan.sub.a .ltoreq.x.sub.a -(x.sub.a .multidot.y),in which x.sub.a is the total number of nucleotides in SEQ ID NO:1, and y has a value of 0.70, wherein any non-integer product of x.sub.a and y is rounded down to the nearest integer prior to subtracting such product from x.sub.a, and wherein said polypeptide has human RCE1 activity.