Patent ID: 8436022
Filing Date: 2013-05-07
Classification: A61P,C07D

Abstract:
1. A biaryl benzoimidazole represented by the following Formula 1, or a pharmaceutically acceptable salt or an isomer thereof, wherein, R m is an integer of 0, 1 or 2; R amine; NH(C R R R R benzyl substituted or unsubstituted with one or more groups selected from the group consisting of hydroxy, halogen, alkyl having 1 to 4 carbon atoms, haloalkyl having 1 to 3 carbon atoms, alkoxy having 1 to 4 carbon atoms, amine, NH(C alkyl having 1 to 6 carbon atoms substituted or unsubstituted with one or more groups selected from the group consisting of hydroxy, halogen, alkyl having 1 to 4 carbon atoms, haloalkyl having 1 to 3 carbon atoms, alkoxy having 1 to 4 carbon atoms, amine, NH(C R R A is (CR p is an integer of 0, 1 or 2; Z is C(═O); C(═O)O; C(═O)NR R R Q Q Q Q Q Q Q Q W is N; X is CR R alkyl having 1 to 10 carbon atoms substituted or unsubstituted with one or more R R R R benzyl substituted or unsubstituted with one or more groups selected from the group consisting of hydroxy, halogen, alkyl having 1 to 4 carbon atoms, haloalkyl having 1 to 3 carbon atoms, alkoxy having 1 to 4 carbon atoms, amine, NH(C alkyl having 1 to 6 carbon atoms substituted or unsubstituted with one or more groups selected from the group consisting of hydroxy, halogen, alkyl having 1 to 4 carbon atoms, haloalkyl having 1 to 3 carbon atoms, alkoxy having 1 to 4 carbon atoms, amine, NH(C alkenyl having 2 to 6 carbon atoms substituted or unsubstituted with one or more groups selected from the group consisting of hydroxy, halogen, alkyl having 1 to 4 carbon atoms, haloalkyl having 1 to 3 carbon atoms, alkoxy having 1 to 4 carbon atoms, amine, NH(C alkynyl having 2 to 6 carbon atoms substituted or unsubstituted with one or more groups selected from the group consisting of hydroxy, halogen, alkyl having 1 to 4 carbon atoms, haloalkyl having 1 to 3 carbon atoms, alkoxy having 1 to 4 carbon atoms, amine, NH(C cycloalkyl having 3 to 8 carbon atoms substituted or unsubstituted with one or more groups selected from the group consisting of hydroxy, halogen, alkyl having 1 to 4 carbon atoms, haloalkyl having 1 to 3 carbon atoms, alkoxy having 1 to 4 carbon atoms, amine, NH(C cycloalkenyl having 5 to 8 carbon atoms substituted or unsubstituted with one or more groups selected from the group consisting of hydroxy, halogen, alkyl having 1 to 4 carbon atoms, haloalkyl having 1 to 3 carbon atoms, alkoxy having 1 to 4 carbon atoms, amine, NH(C R