Patent ID: 6171834
Filing Date: 2001-01-09
Classification: C12N,C12Q,Y10S

Abstract:
An isolated MurI protein from Streptococcus pneumoniae having the amino acid sequence:Met Asp Asn Arg Pro Ile Gly Phe Leu Asp Ser 1 5 10 Gly Val Gly Gly Leu Thr Val Val Arg Glu Leu 15 20 Met Arg Gln Leu Pro His Glu Glu Ile Val Tyr 25 30 Ile Gly Asp Ser Ala Arg Ala Pro Tyr Gly Pro 35 40 Arg Pro Ala Glu Gln Ile Arg Glu Tyr Thr Trp 45 50 55 Gln Leu Val Asn Phe Leu Leu Thr Lys Asp Val 60 65 Lys Met Ile Val Ile Ala Cys Asn Thr Ala Thr 70 75 Ala Val Val Trp Glu Glu Ile Lys Ala Gln Leu 80 85 Asp Ile Pro Val Leu Gly Val Ile Leu Pro Gly 90 95 Ala Ser Ala Ala Ile Lys Ser Ser Gln Gly Gly 100 105 110 Lys Ile Gly Val Ile Gly Thr Pro Met Thr Val 115 120 Gln Ser Asp Ile Tyr Arg Gln Lys Ile His Asp 125 130 Leu Asp Pro Asp Leu Gln Val Glu Ser Leu Ala 135 140 Cys Pro Lys Phe Ala Pro Leu Val Glu Ser Gly 145 150 Ala Leu Ser Thr Ser Val Thr Lys Lys Val Val 155 160 165 Tyr Glu Thr Leu Arg Pro Leu Val Gly Lys Val 170 175 Asp Ser Leu Ile Leu Gly Cys Thr His Tyr Pro 180 185 Leu Leu Arg Pro Ile Ile Gln Asn Val Met Gly 190 195 Pro Lys Val Gln Leu Ile Asp Ser Gly Ala Glu 200 205 Cys Val Arg Asp Ile Ser Val Leu Leu Asn Tyr 210 215 220 Phe Glu Ile Asn Arg Gly Arg Asp Ala Gly Pro 225 230 Leu His His Arg Phe Tyr Thr Thr Ala Ser Ser 235 240 Gln Ser Phe Ala Gln Ile Gly Glu Glu Trp Leu 245 250 Glu Lys Glu Ile His Val Glu His Val Glu Leu 255 260