Patent ID: 9200067
Filing Date: 2015-12-01
Classification: A61P,C07K,G01N

Abstract:
1. A method for treating a human breast cancer patient, said method comprising: (a) contacting a breast cancer sample from the patient with a monoclonal antibody or a polyclonal antibody that binds specifically to CUE domain-containing 2 (CUEDC2) protein, thereby determining the expression level of the CUEDC2 protein in the sample; (b) comparing the CUEDC2 protein expression level determined in (a) to a given value, wherein a CUEDC2 protein in expression level lower than the given value indicates a higher sensitivity of the patient to tamoxifen, and a CUEDC2 protein expression level equal to or higher than the given value indicates a lower sensitivity of the patient to tamoxifen, and (c) administering tamoxifen to the patient indicated in (b) as having a higher sensitivity to tamoxifen.