Patent ID: 6740039
Filing Date: 2004-05-25
Classification: A61B,A61M,A61N

Abstract:
A method for administering a therapeutic agent to a patient, comprising the steps of:delivering a therapeutic agent to a region of interest in a patient; generating an ultrasound image of the region of interest at a first ultrasound frequency selected for image quality; transmitting ultrasound energy at a second ultrasound frequency that is not equal to the first ultrasound frequency, said second ultrasound frequency being transmitted to the region of interest for activating the therapeutic agent; and generating a parameter display including an amount of microbubble destruction in the defined region of interest that is indicative of activation of the therapeutic agent in the region of interest and provides feedback control for said activating step; and automatically adjusting a parameter related to the second ultrasound frequency in accordance with feedback control, wherein said parameter to be adjusted includes one of frequency, power level, beam pattern, or duration of the transmission of the ultrasound energy.