Patent ID: 6315900
Filing Date: 2001-11-13
Classification: B01D,B01J,C07K

Abstract:
A system for affinity separation of a target compound from a fluid comprising:a) a static filtration apparatus comprising a housing having a feed port, a concentrate port, a filtrate port, and a filtration medium disposed within the housing:b) the feed port and the concentrate port being in fluid communication with the upstream side of the filtration medium, while the filtrate port is in fluid communication with the downstream side of the filtration medium; andc) a suspension comprising a plurality of low porosity, low non-specific binding, reconstituted cellulose affinity particles having a ligand grafted thereon and a fluid containing a sheer sensitive target compound to be isolated possessing an affinity for the ligands fed into the filtration apparatus via the feed port for inter-mixing.