Patent ID: 6190869
Filing Date: 2001-02-20
Classification: A61K,A61P,C07H,C12N,C12Q,C12Y,Y02P

Abstract:
An antisense compound 8 to 30 nucleobases in length targeted to nucleotides 35 to 55 of a 3'-untranslated region, nucleotides 76 to 117 of a start codon, nucleotides 139 to 2214 of a coding region, nucleotides 2196 to 2224 of a region which overlaps at least one nucleotide of a stop codon or nucleotides 2223 to 2743 of a 5'-untranslated region of a nucleic acid molecule encoding human Protein kinase C-theta, wherein said antisense compound specifically hybridizes with and inhibits the expression of human Protein kinase C-theta.