Patent ID: 6685958
Filing Date: 2004-02-03
Classification: A61K,A61P,Y02A,Y10S

Abstract:
A topical ophthalmic broad spectrum antibiotic composition comprising: from about 0.005% to about 10% by weight, based upon the total weight of the composition, of a quinolone carboxylic acid derivative of formula (I), wherein R1 is a hydrogen atom, an alkyl group, an aralkyl group, an ester residual group which can be hydrolyzed in vivo, R2 is a hydrogen atom or an amino group which may be substituted by one or two lower alkyl groups, X is a hydrogen atom or a halogen atom, Y is CH2, O, S, SO, SO2, or Nâ€”R3, wherein R3 is a hydrogen atom or a lower alkyl group, and Z is an oxygen atom or two hydrogen atoms; and a carboxy containing polymer; wherein said topical ophthalmic broad spectrum antibiotic composition is nonirritating to ocular tissue.