Patent ID: 6013809
Filing Date: 2000-01-11
Classification: A61P,C07D

Abstract:
A heterocyclic benzocycloalkene derivative corresponding to formula I: ##STR7## wherein R.sup.1 denotes an OH, C.sub.1-6 -alkoxy or --O--(C.sub.3-7)-cycloalkyl group;R.sup.2 denotes a C.sub.1-6 -alkyl group;R.sup.3 denotes a C.sub.1-6 -alkyl, --CH.sub.2 --CH.dbd.C(R.sup.6).sub.2, or --CH.sub.2 --(C.sub.3-7)-cycloalkyl group;R.sup.4 and R.sup.5 each independently denotes H, Cl, F, CF.sub.3, OH, or a C.sub.1-6 -alkyl, OH, C.sub.1-6 -alkoxy, O--(C.sub.3-7)-cycloalkyl, --(CH.sub.2).sub.0-2 -aryl, .alpha.,.beta.- or .beta.,.gamma.--O--(CH.sub.2).sub.1-2 --O--, --O--(CH.sub.2).sub.0-2 -aryl, heterocyclyl, .alpha.,.beta.- or .beta.,.gamma.-benzo group which is unsubstituted or mono- or disubstituted with F, Cl, CF.sub.3, OH, C.sub.1-6 -alkyl, C.sub.1-6 -alkoxy, or --CON(R.sup.6 R.sup.7);R.sup.6 denotes H or a C.sub.1-6 -alkyl group;R.sup.7 denotes H, or a C.sub.1-6 -alkyl, --(CH.sub.2).sub.0-2 -aryl, or --CH.sub.2 --(C.sub.3-7)-cycloalkyl group; orR.sup.6 and R.sup.7 together denote a --(CH.sub.2).sub.5-7 --, or --(CH.sub.2).sub.2 --O--(CH.sub.2).sub.2 -- group;X denotes O, S, SO or SO.sub.2, andY denotes a --(CH.sub.2).sub.1-2 --, --CH.sub.2 --C(CH.sub.3).sub.2 --, or --C(CH.sub.3).sub.2 -- group; or a pharmaceutically acceptable salt thereof.