Patent ID: 6843988
Filing Date: 2005-01-18
Classification: A61K,C07K

Abstract:
1. A method for increasing interferon activity in an individual comprising administering to such individual a therapeutically effective amount of an isolated Synferon polypeptide comprising an amino acid sequence that is at least 90% identical to a sequence selected from the group consisting of: (a) amino acid residues 1 to 161 of SEQ ID NO:2; and (b) amino acid residues 1 to 161 of SEQ ID NO:2; wherein said polypeptide exhibits an activity selected from the group consisting of: (i) anti-viral activity in vitro; (ii) bone marrow colony formation in vitro; and (iii) inhibition of GM-CSF induced proliferation of the erythroleukemic cell line TF-1.