Patent ID: 6323181
Filing Date: 2001-11-27
Classification: A61K,A61P,C07C,C07D,C07K,Y02A

Abstract:
A compound of formula (I): ##STR4##whereinR.sub.1 is CH.sub.2 -[sulfur-linked-N-acylcysteine]-Rx;R.sub.2 is methyl;R.sub.3 is hydrogen;R.sub.4 is methyl;R.sub.5 is hydroxy;R.sub.6 is methyl; andRx is --Leu-Leu-Leu, --Leu-Phe-Leu, --Leu-Gly-Leu, --Leu-Leu-Phe, --Leu-Phe-Phe, --Leu-Gly-Phe, --Leu-Leu-Gly, --Leu-Phe-Gly, --Leu-Gly-Gly, --Phe-Leu-Leu, --Phe-Phe-Leu, --Phe-Gly-Leu, --Gly-Leu-Leu, --Gly-Phe-Leu, --Gly-Gly-Leu, --Leu-Leu, --Phe-Leu, --Gly-Leu, --Leu-Leu-Phe, --Phe-Phe-Phe, --Phe-Gly-Phe, --Gly-Leu-Phe, --Gly-Phe-Phe, --Gly-Gly-Phe, --Leu-Phe, --Phe-Phe, --Gly-Phe, --Phe-Leu-Gly, --Phe-Phe-Gly, --Phe-Gly-Gly, --Phe-Leu-Gly, --Gly-Phe-Gly, --Gly-Gly-Gly, --Leu-Gly, --Phe-Gly, or --Gly-Gly; or a pharmaceutically acceptable salt thereof.