Patent ID: 7122371
Filing Date: 2006-10-17
Classification: C12N

Abstract:
1. A modular cell culture bioreactor apparatus, said apparatus comprising: a plurality of cell culture chambers; at least one reservoir containing a cell support medium; a plurality of conduits fluidly connecting said at least one reservoir with said plurality of chambers; and at least one pump fluidly connected through said plurality of conduits with said at least one reservoir and with said plurality of chambers to pump cell support medium therethrough; wherein each individual chamber of said plurality of chambers includes at least one three-dimensional matrix comprising nonwoven fibrous polyethylene terephthalate having a random microscopic structure, a plurality of channels carrying the cell support medium and having said matrix positioned in fluid communication therebetween, and at least two openings into each said channel, wherein a first said opening is in fluid connection with said pump and a second said opening is in fluid connection with said reservoir.