Patent ID: 7348157
Filing Date: 2008-03-25
Classification: G01N,Y10S,Y10T

Abstract:
1. An immunoassay for detection and/or quantification of cardiac troponin I (cTnI) in a sample derived from an individual's blood, comprising contacting said sample with at least two capture antibodies capable of binding to said cTnI and at least one tracer antibody capable of binding to said cTnI or to TnC complexed with cTnI, detecting a signal from said tracer antibody, and comparing said signal against a signal obtained from a standard having a known concentration of cardiac troponin I, wherein a first capture antibody is directed to a portion of the cTnI midfragment which is the epitope region 30-69 aa, and wherein a second capture antibody is directed to the N-terminal portion of cTnI or to the C-terminal portion of cTnI.