Patent ID: 7358081
Filing Date: 2008-04-15
Classification: G01N

Abstract:
1. A device for the electrochemical detection of a nucleotide sequence in a fluid comprising: a working electrode attached to a top section of a molded plastic part; a counter-electrode attached to a bottom section of the molded plastic part, wherein the working electrode is attached to a biopolymer that has a specific affinity with the nucleotide sequence to be detected and the molded plastic part is foldable in such a way that the working electrode comes to lie above the counter electrode and wall elements of the top and bottom sections of the molded plastic part are connected to one another to form a sealed fluid tight housing of an exchangeable analysis cassette; the exchangeable analysis cassette formed being operable to accept the introduction of the fluid and having the working electrode and the counter-electrode arranged within the sealed fluid tight housing of the analysis cassette and can be contacted with the fluid, the sealed fluid tight housing comprising a compressible area such that an exertion of a force on the analysis cassette after assembly moves the working electrode and the counter electrode toward each other within the sealed fluid tight housing; a portable computer arrangement electrically connected with the analysis cassette comprising a display and an energy source, the energy source being independent of an electrical supply net, wherein at least one of a voltage and a current can be impressed on at least one of the working electrode and the counter-electrode; wherein at least one of a current and a voltage signal can be detected as a consequence of the nucleotide sequence to be detected being deposited on the working electrode; and wherein a detection result can be represented on the display; and a temperature-regulating element for cooling and/or heating the fluid in the analysis cassette, the temperature-regulating element being fed from the energy source.