Patent ID: 7849581
Filing Date: 2010-12-14
Classification: B01D,Y10S,Y10T

Abstract:
1. A method of preparing a conical nanopore membrane, comprising: sealing a conical tip of an internal signal transduction element in a substrate; polishing the substrate in order to expose the conical tip of the internal signal transduction element; monitoring an extent of the polishing using a tester; stopping the polishing when the tester signifies that a disk of a desired radius is exposed, thus producing a nanodisk electrode; and removing the internal signal transduction element from the substrate, after the nanodisk electrode is created, thus producing a nanopore membrane having a thickness, with a first, exterior, side and a second, interior, side, with the first side being opposite the second side, and having a nanopore extending through the membrane, thus forming a channel connecting the first side to the second side of the membrane, wherein the nanopore has a first opening that opens to the first side of the membrane, a second opening that opens to the second side of the membrane, and a depth.