Patent ID: 8980927
Filing Date: 2015-03-17
Classification: A61K,A61P,C07D

Abstract:
1. A method for the treatment of a disease or condition mediated by PGD 2 or other agonist at the CRTH2 receptor comprising administering to a patient in need of such treatment a suitable amount of a compound of formula (II): wherein W is chloro or fluoro; R each R p and q are each independently an integer from 1 to 3; and R or a pharmaceutically acceptable salt, hydrate, solvate, complex, or prodrug thereof; wherein the disease or condition mediated by PGD 2 or other agonist at the CRTH2 receptor is selected from the group consisting of an infection due to rhinovirus, coronavirus, respiratory syncytial virus, influenza, or adenovirus; contact hypersensitivity; contact dermatitis; male-pattern baldness; eosinophilic bronchitis; eosinophilic oesophagitis; and gastroesophageal reflux disease (GERD).