Patent ID: 8133510
Filing Date: 2012-03-13
Classification: A61K,C08B,C08J

Abstract:
1. A process for producing a dosage form in film form for surface administration of at least one active ingredient and/or nutrient to a living creature comprising at least one active ingredient-containing and/or nutrient-containing layer based on hydrophilic polymers crosslinked with at least one polyacrylic acid derivative by building up individual layers successively on a smooth surface, characterized by the steps: a) simultaneous spraying of (1) an aqueous solution of the hydrophilic polymers and of the active ingredient and/or of the nutrient and (2) of an aqueous solution of the polyacrylic acid derivative, wherein the aqueous solution of the hydrophilic polymers and of the active ingredient and/or of the nutrient and aqueous solution of polyacrylic acid derivative are mixed after spraying and the hydrophilic polymers are crosslinked by the polyacrylic acid derivative in situ; and b) removal of the water by drying.