Patent ID: 8754216
Filing Date: 2014-06-17
Classification: A61K,A61P,C07D

Abstract:
1. A method of treating an NK1 receptor mediated disease comprising: administering to a patient in need thereof an oral dosage form comprising an effective amount of at least one compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: R with the proviso that at least one of R W is ═C(R X is —C(O)— or —S(O Y is selected from the group consisting of —CH (a) the nitrogen atom of —N(R (b) if R and Y is —O—, X is not —S(O Z is —C(R R R R R R each R R R Ar Ar n is 0, 1, or 2; and m is 1, 2 or 3.