Patent ID: 7498445
Filing Date: 2009-03-03
Classification: A61K,C07D

Abstract:
1. An NO-donating compound selected from the group consisting of: 4-Methyl-5-(-2-nitrooxy-ethyl)-2-(1-nitrooxy-ethyl)-thiazole (Pet-5); 1,4-Bis-[4-Methyl-5-(2-nitrooxy)-ethyl)-thiazol-2-yl]-Butane (Pet-13); 1,2-Bis-[4-methyl-5-(2-nitrooxy-ethyl)-thiazol-2-yl]-ethane (Pet-15); Bis-[4-Methyl-5-(2-nitrooxy)-ethyl)-thiazol-2-yl]-methane (Pet-16); N,N′-Bis-[4-methyl-5-(2-nitrooxy-ethyl)-thiazol-2-yl]-hydrazine (Pet-42); Bis-[4-methyl-5-(2-nitrooxy-ethyl)-thiazol-2-yl]-disulfide (Pet-54); 4-Methyl-5-(2-nitrooxy-ethyl)-2-(4-nitrooxy-pyrrolidin-2-yl)-thiazole (Pet 93); 4-Methyl-5-(2-nitrooxy-ethyl)-2-(nitrooxy-thiophen-2-yl-methyl)-thiazole (Pet-95); N-[4-Methyl-5-(2-nitrooxy-ethyl)-thiazol-2-yl]-2-nitrooxy-acetamide (Pet 96); Bis-[4-methyl-5-(2-nitrooxy-ethyl)-thiazole-2-yl]-diazene (Pet-102); 4,4′-Bis-[4-methyl-5-(2-nitrooxy-ethyl)-thiazole-2-yl]-diphenyl-disulfide (Pet-115); and 4,4′-Dimethyl-5,5′-bis-(2-nitrooxy-ethyl)-[2,2′]bithiazolyl (Pet-118).