Patent ID: 6410528
Filing Date: 2002-06-25
Classification: A61P,C07D

Abstract:
A compound of formula (I) and physiologically acceptable salts and or metabolically labile derivatives thereof, wherein R1 represents C1-6 straight or branched chain alkyl, C1-6 straight or branched chain alkoxy, optionally substituted phenoxy, C3-6straight or branched chain alkenyloxy (optionally substituted by 1 or 2 halogen atoms) or C1-4 straight or branched alkoxy substituted by an optionally substituted phenyl group, C3-8 straight or branched chain alkynyl, C3-6 straight or branched chain alkenyl (optionally substituted by C1-4alkoxy or 1 or 2 halogen atoms), optionally substituted phenyl, optionally substituted C3-7 cycloalkyl, optionally substituted C5-7 cycloalkenyl, C2-4 straight or branched chain alkyl substituted by (C1-4 alkoxy, C1-4 alkyl thio or halogen), C1-4 straight or branched chain alkyl substituted by (C1-4 alkoxycarbonyl, arylalkyloxycarbonyl, aryloxycarbonyl, propadienyl, cyano, optionally substituted C3-7 cycloalkyl, optionally substituted 5 or 6 membered heteroaryl, or 1 or 2 optionally substituted phenyl groups), or methyl substituted by C1-6 alkanoyl or optionally substituted benzoyl; R2 represents a group selected from hydrogen, C1-6 straight or branched chain alkyl, C3-6 straight or branched chain alkenyl, optionally substituted phenyl or C1-4 alkyl substituted with a group selected from C1-4alkoxy, hydroxy, acyloxy, alkoxy carbonyl or aryloxycarbonyl, and R3 represents a group selected from formyl or cyano.