Patent ID: 6645947
Filing Date: 2003-11-11
Classification: A61K,A61L,C12N

Abstract:
A method of inhibiting fibroblast attachment in an Ex vivo cell-based product selected from the group consisting of cell cultures, blood and plasma in contact with a solid support comprising contacting said cell based product with a solid support having a N,O-carboxymethylchitosan coating, said N,O-carboxymethylchitosan coating being selected from the group consisting of solutions, hydrogels, pastes, rehydratable films, creams, foams, and sponges of N,O-carboxymethylchitosan which is adherent to freshly excised tissue with a force of at least 100 dynes/cm2, said coating providing inhibition of attachment of fibroblasts to said solid support.