Patent ID: 8962826
Filing Date: 2015-02-24
Classification: C07D

Abstract:
1. A process for producing a lactam, comprising: reacting a cyclic ketone and hydroxylamine to give an oxime; and conducting Beckmann rearrangement of the oxime using a Beckmann rearrangement catalyst to give a lactam, wherein the rearrangement catalyst is at least one selected from the group consisting of 4-chloro-3,5-dinitrobenzonitrile, picryl chloride, 2-chloro-3,5-dinitropyridine, trichlorotriazine, thionyl chloride, phosphorous trichloride and phosphorous pentachloride; and purifying one or more of compounds selected from the group consisting of a cyclic ketone, an oxime and a lactam by hydrogenation and/or crystallization, wherein the lactam is caprolactam and/or laurolactam, the cyclic ketone is cyclohexanone and/or cyclododecanone, and the oxime is cyclohexanone oxime and/or cyclododecanone oxime.