Patent ID: 6902718
Filing Date: 2005-06-07
Classification: A61K

Abstract:
1. A composition comprising: (1) a radiopharmaceutical precursor comprising a chelator optionally covalently linked to a targeting domain or a targeting moiety selected from the group consisting of an antibody, a Fab antibody fragment, a F(ab)′ 2 antibody fragment, an epitone binding complementarity determining region derived from an antibody, a peptide, a growth factor, a receptor binding fragment of a growth factor, a hormone, a steroid, a receptor binding nuecleic acid, a receptor binding monosaccharide, a receptor binding disaccharide, a receptor binding oligosaccharide, a receptor-binding lipid, and a recertor binding antibiotic; and (2) a stabilizing amount of a hydrophilic thioether of the formula wherein: R is C R R and with the further proviso that the hydrophilic thioether comprise at least one of said hydrophilic groups.