Patent ID: 8323676
Filing Date: 2012-12-04
Classification: A61L

Abstract:
1. An implantable medical device comprising: a device body and a coating disposed over the device body, the coating comprising: wherein the mass ratio of the peptide or protein to the hydrophobic drug is from about 1:0.1 to about 1:10; wherein the mass ratio of the protein or peptide to the polymer is from about 1:0.1 to about 1:10; wherein the cumulative release of the peptide or protein from the drug reservoir layer is between about 5% and about 50% at 24 hours and between about 10% and about 95% at 7 days; and wherein the polymer is a poly(ester-amide) or a poly(amide) that is of the following formula: wherein: i is an integer from 1 to 10, inclusive; j is an integer from 0 to 10, inclusive; k is an integer from 0 to 15, inclusive; x y p is an integer from 2 to about 4500; M s s t v with the proviso that each A each B and each C wherein: each R phenyl and or one or more of R each R where z is 0, 1, or 2; subject to the restriction that at least one R where z is 0, 1, or 2; R each R