Patent ID: 7645863
Filing Date: 2010-01-12
Classification: A61P,C07D

Abstract:
1. A method for purifying moxidectin, said method comprising: a) providing a solution of moxidectin, wherein the moxidectin is dissolved or prepared in a first organic solvent; b) concentrating said provided moxidectin solution such that the percentage of total solids in the concentrated moxidectin solution is about 40-50% by weight; c) adding a second organic solvent to said concentrated moxidectin solution, wherein said second organic solvent is present in a weight ratio of 2:1 to 6:1 with respect to said first organic solvent; and said second organic solvent is a non-polar organic solvent; d) lowering the temperature of the moxidectin solution formed in c), so as to form moxidectin crystals; and e) recovering said moxidectin crystals.