Patent ID: 7393871
Filing Date: 2008-07-01
Classification: C07F

Abstract:
1. A method of treating tumoral pathologies in a patient, said method comprising administering to the patient a therapeutically effective amount of a neutral ruthenium (II) complex having the formula [RuA a M m P p W] r or a salt of an anionic ruthenium complex having the formula [RuA a M m P p W] r , wherein: A represents a halogen chosen from the group consisting of Cl W represents NO M represents SOR P represents NR a is a whole number between 3 and 4; m is a whole number between 0 and 2; p is a whole number between 0 and 1; r can be 0, −1, or −2; a+m+p=5 R R L represents a heterocyclic ligand containing at least two nitrogen atoms whose electron pairs are involved in the bond with the two ruthenium atoms present in the complex, with the proviso that when said nitrogen atoms are not contained on the same heterocyclic ring L is B′-X-B″, B′ and B″ being nitrogen heterocyclic compounds and X being chosen from the group consisting of —COO—, —O—, —(CH