Patent ID: 6051577
Filing Date: 2000-04-18
Classification: A61P,C07D

Abstract:
A Compound of formula I ##STR10## wherein R.sub.1 is phenyl unsubstituted or substituted by one, two or three substituents selected from the group consisting of lower alkyl, hydroxy-lower alkyl, phenyl, lower alkoxy, phenyl-lower alkoxy, C.sub.1 -C.sub.3 alkylenedioxy, cyano, and halogen;R.sub.2 and R.sub.3 are simultaneously or each independently of the other hydrogen, lower alkyl or halogen;R.sub.4 is hydrogen, hydroxy, lower alkyl, lower alkoxy, lower alkyleneoxy-lower alkyl, lower alkoxycarbonyl, N-lower alkylaminocarbonyl or N,N-di-lower alkylaminocarbonyl;R.sub.5 is hydrogen, lower alkyl, lower alkylcarbonyl or lower alkoxycarbonyl;wherein alkyl, by itself or as a constituent of another group, may be unsubstituted or substituted lay a substituent selected from the group consisting of halogen, hydroxy, lower alkoxy, trifluoromethyl, morpholin-4-yl, amino, N-lower alkylamino, and N,N-di-lower alkylamino;m is 1 or2;n is an integer from 0 to 4 inclusive;or pharmaceutically acceptable salts thereof.