Patent ID: 7465728
Filing Date: 2008-12-16
Classification: A61P,C07D

Abstract:
1. A compound of the formula (IA), (IB), (IC), (ID), (IE) and (IF) of the generic structure of formula (I): wherein: i) a compound of formula (IA) is selected from: wherein: R R or a pharmaceutically acceptable salt or an in vivo hydrolysable ester thereof; ii) a compound of formula (IB) is selected from: wherein: R R or a pharmaceutically acceptable salt thereof; provided that when R iii) a compound of formula (IC) is selected from: wherein: R R or a pharmaceutically acceptable salt thereof; provided that when R iv) a compound of formula (ID) is selected from: wherein: R R R or a pharmaceutically acceptable salt thereof; v) a compound of formula (IE) is selected from: wherein: R R p is 1-2; wherein the values of R R R or a pharmaceutically acceptable salt thereof; provided that said compound is not 4-(1,2-dimethylimidazol-5-yl)-2-[2-methoxy-4-(N-methylsulphamoyl)-5-methylanilino]pyrimidine; vi) a compound of formula (IF) is selected from: wherein: R R p is 0-2; wherein the values of R R R R or a pharmaceutically acceptable salt thereof.