Patent ID: 6384235
Filing Date: 2002-05-07
Classification: C07D

Abstract:
A process for preparing compounds of the indole type of the formula in which A is a hydrocarbon radical which, together with the carbons to which it is attached, forms a substituted or unsubstituted mono- or polycyclic aromatic system which does or does not contain one or more heteroatoms from the group consisting of N, O and S, and R1, R2 independently of one another are H, a saturated, linear or branched aliphatic C1-C20-hydrocarbon radical, an unsaturated, linear or branched aliphatic C2-C20-hydrocarbon radical, a saturated or unsaturated, unsubstituted or alkyl-substituted cycloaliphatic C3-C20-hydrocarbon radical or an aromatic C5-C20-hydrocarbon radical, where these radicals optionally contain in their molecular skeleton one or more heteroatoms from the group consisting of the halogens, N, P, O, S, Si, Sn and B and is or is not substituted or unsubstituted, which comprises cyclizing of alkynylaminoaromatics of the formula in which R1 and R2 are as defined in formula (I) and R1, R2 or A is optionally attached to an organic or inorganic carrier,in a polar aprotic ion-solvating solvent in the presence of a compound of Na, K, Rb or Cs which dissociates well in the solvent mentioned and whose ions are sufficiently solvated by the solvent compound of Na, K, Rb or Cs.