Patent ID: 7041820
Filing Date: 2006-05-09
Classification: C07D

Abstract:
1. A process for producing a (dioxolenon-4-yl)methyl ester derivative of formula (3) (where Q represents the fused heterocyclic group having a β-lactam ring of the following formulae: where r 1 and r 4 represent a 1-hydroxyethyl group or an optionally substituted benzoylamino group; r 2 , r 5, r 6 , r 7 and r 8 each independently represent hydrogen or a C 1-6 alkyl group that may be optionally substituted by G 1 ; a C 2-6 alkenyl group that may be optionally substituted by G 1 ; a C 2-6 alkynyl group that may be optionally substituted by G 1 ; a tetrahydrofuranyl and a heterocyclic group that may optionally be substituted by G 1 ; G G R (where Q has the same meaning as defined above, M represents a hydrogen atom, an alkali metal, an alkaline earth metal or a transition metal, and n represents the atomic valency of M) with a 4-chloromethyldioxolenone compound of formula (2) (where R 1 and R 2 have the same meanings as defined above) in a solvent in the presence of both a phase transfer catalyst and a metal iodide.