Patent ID: 9034886
Filing Date: 2015-05-19
Classification: A61P,C07D

Abstract:
1. A compound selected from the group consisting of: V-1 N-(2-aminophenyl)-4-(quinazoline-4-amino)benzamide, V-2 N-(2-amino-4-pyridyl)-4-(quinazoline-4-amino)benzamide, V-3 N-(2-amino-5-fluorophenyl)-4-(quinazoline-4-amino)benzamide, V-4 N-(2-amino-4-pyridyl)-4-(6,7-dimethoxyquinazoline-4-amino)benzamide, V-5 N-(2-aminophenyl)-4-(6-methoxyquinazoline-4-amino)benzamide, V-6 N-(2-amino-5-fluorophenyl)-4-(6-methoxyquinazoline-4-amino)benzamide, V-7 N-(2-aminophenyl) 4-(5-methoxyquinazoline-4-amino)benzamide, V-8 N-(2-amino-4-pyridyl)-4-(5-methoxyquinazoline-4-amino)benzamide, V-9 N-(2-aminophenyl)-4-(8-methoxyquinazoline-4-amino)benzamide, V-10 N-(2-amino-5-fluorophenyl)-4-(8-methoxyquinazoline-4-amino)benzamide, V-11 N-(2-aminophenyl)-4-(6-nitroquinazoline-4-amino)benzamide, V-12 N-(2-aminophenyl)-4-(6-fluoroquinazoline-4-amino)benzamide, V-13 N-(2-aminophenyl)-4-(7-fluoroquinazoline-4-amino)benzamide, V-14 N-(2-amino-5-fluorophenyl)-4-(8-fluoroquinazoline-4-amino)benzamide, V-15 N-(2-aminophenyl)-4-(6,7-dimethoxyethoxyquinazoline-4-amino)benzamide, V-16 N-(2-amino-4-pyridyl)-4-(6,7-dimethoxyethoxyquinazoline-4-amino)benzamide, V-17 N-(2-aminophenyl)-4-[7-methoxy-6-(3-morpholinylpropoxy)quinazoline-4-amino]benzamide, V-18 N-(2-amino-5-fluorophenyl)-4-[7-methoxy-6-(3-morpholinyl propoxy)quinazoline-4-amino]benzamide, V-19 N-(2-aminophenyl)-4-[6-(5-((2-(methylsulfonyl)ethylamino)methyl)furyl)quinazoline-4-amino]benzamide, V-20 N-(2-amino-5-fluorophenyl)-4-[6-(5-((2-(methylsulfonyl)ethylamino)methyl)furyl)quinazoline-4-amino]benzamide, V-21 N-(2-aminophenyl)-4-(6-acetamidoquinazoline-4-amino)benzamide, V-22 N-(2-aminophenyl)-4-(6-methoxycarbonylmethylquinazoline-4-amino)benzamide, V-23 N-[2-amino-5-(2-thienyl)phenyl]-4-(6,7-dimethoxyquinazoline-4-amino)benzamide, V-24 N-[2-amino-5-(phenyl)phenyl]-4-(6,7-dimethoxyquinazoline-4-amino)benzamide, V-25 N-[2-amino-5-(2-furyl)phenyl]-4-(6,7-dimethoxyquinazoline-4-amino)benzamide, V-26 N-(2-amino-4-pyridyl)-4-[(quinazoline-4-amino)methyl]benzamide, V-27 N-(2-aminophenyl)-4-[(quinazoline-4-amino)methyl]benzamide, V-28 N-[2-amino-5-(2-thienyl)phenyl]-4-[(quinazoline-4-amino)methyl]benzamide, V-29 N-(2-amino-5-fluorophenyl)-4-[(quinazoline-4-amino)methyl]benzamide, V-30 N-(2-amino-4-pyridyl)-4-[(6,7-dimethoxyquinazoline-4-amino)methyl]benzamide, V-31 N-[2-amino-5-(2-thienyl)phenyl]-4-[(6,7-dimethoxyquinazoline-4-amino)methyl]benzamide, V-32 N-(2-aminophenyl)-4-[(7-methoxyquinazoline-4-amino)methyl]benzamide, V-33 N-(2-aminophenyl)-4-[(6-methoxyquinazoline-4-amino)methyl]benzamide, V-34 N-(2-aminophenyl)-4-[(8-methoxyquinazoline-4-amino)methyl]benzamide, V-35 N-(2-amino-5-fluorophenyl)-4-[(8-methoxyquinazoline-4-amino)methyl]benzamide, V-36 N-(2-amino-5-(phenyl)phenyl)-4-[(8-methoxyquinazoline-4-amino)methyl]benzamide, V-37 N-(2-aminophenyl)-4-[(6-nitroquinazoline-4-amino)methyl]benzamide, V-38 N-(2-aminophenyl)-4-[(6,7-dimethoxyethoxyquinazoline-4-amino)methyl]benzamide, V-39 N-(2-amino-4-pyridyl)-4-[(6,7-dimethoxyethoxyquinazoline-4-amino)methyl]benzamide, V-40 N-(2-amino-5-fluorophenyl)-4-[(6,7-dimethoxyethoxyquinazoline-4-amino)methyl]benzamide, V-41 N-(2-aminophenyl)-4-[(7-methoxy-6-(3-morpholinylpropoxy)quinazoline-4-amino)methyl]benzamide, V-42 N-(2-amino-4-pyridyl)-4-[(7-methoxy-6-(3-morpholinylpropoxy)quinazoline-4-amino)methyl]benzamide, V-43 N-(2-aminophenyl)-4-[(8-fluoroquinazoline-4-amino)methyl]benzamide, V-44 N-(2-amino-4-pyridyl)-4-[(8-fluoroquinazoline-4-amino)methyl]benzamide, V-45 N-(2-amino-5-(2-furyl)phenyl)-4-[(8-fluoroquinazoline-4-amino)methyl]benzamide, V-46 N-(2-aminophenyl)-4-[(6-acetamidoquinazoline-4-amino)methyl]benzamide, V-47 N-(2-amino-4-pyridyl)-4-[(6-acetamidoquinazoline-4-amino)methyl]benzamide, or V-48 N-[2-amino-5-(2-furyl)phenyl]-4-[(6-acetamidoquinazoline-4-amino)methyl]benzamide.