Patent ID: 9186432
Filing Date: 2015-11-17
Classification: A61L,B05D,C08L,D04C,D10B

Abstract:
1. A method of making a non-absorbable, high strength suture comprising a jacket comprising a plurality of braided untreated multi-filament yarns formed of ultrahigh molecular weight polyethylene, the suture being coated with native collagen, consisting of the steps of: dissolving native collagen in an acidic solution of acetic acid of about 0.1% concentration to form a stock solution of dissolved native collagen, wherein stock solution of dissolved native collagen has a final concentration of about 0.5 mg/ml; further diluting the stock solution of dissolved native collagen with water to obtain a diluted solution of dissolved native collagen; soaking the braided untreated suture in the diluted solution of dissolved native collagen at a temperature of 4° C. to coat the braided suture with native collagen; drying for about 1 hour the braided suture soaked with native collagen to reduce moisture content of the collagen and obtain a collagen-coated suture with a collagen coating, the collagen coating stimulating proliferation and protein synthesis and providing structural support to the collagen-coated suture; and storing the collagen-coated suture at room temperature for future use, wherein the jacket comprises yarns of the ultrahigh molecular weight polyethylene braided with yarns of polyester.