Patent ID: 6495680
Filing Date: 2002-12-17
Classification: A61K,B82Y,C07C,C08G

Abstract:
A helical composition comprising a plurality of aromatic substituents linked by at least one amide group, the composition having a curved backbone due at least in part to intramolecular hydrogen bonds that rigidify the amide linkage of each amide group to each aromatic substituent and at least in part to an interaction between the aromatic substituents, whereby the curved backbone is stabilized, wherein the composition comprises a plurality of aromatic substituents having a Structure A: wherein R is selected from linear and branched chain alkyl groups, aryl groups including phenyl, benzyl, napthyl, or alkyl or aryl groups with polar terminal functional ends including â€”OH, â€”COOH, â€”NH2, â€”NH3+, â€”N+Râ€²3, â€”CH2CH2C6H5, CH2C6H4â€”pâ€”OH, â€”CH2COOCH3, â€”CH2CONH2, CH2CH2CONH2, â€”CH2COOCH2â€”(3-indolyol).