Patent ID: 9212395
Filing Date: 2015-12-15
Classification: C12Q,Y10T

Abstract:
1. A method for determining whether a human male child has a reduced risk of childhood acute lymphoblastic leukemia (ALL), comprising the steps of: (a) obtaining a biological sample from a human male child; (b) isolating nucleic acid from said biological sample; (c) performing a polymerase chain reaction-restriction fragment length polymorphism assay (PCR-RFLP) in the isolated nucleic acid obtained in (b), said PCR-RFLP comprises the steps of: (d) determining heterozygosity for thymine (T) allele at said haplotype tagging SNP rs807212 in said amplicon based on the presence of said plurality of fragments; and (e) determining that said human male child has a reduced risk of childhood ALL based on said determined heterozygosity.