Patent ID: 6756194
Filing Date: 2004-06-29
Classification: G01N

Abstract:
A composition for use as a standardized measure of apoptosis in a test tissue sample from a subject, the composition comprising:at least one segment of a naturally occurring tissue that-has been subjected to a treatment that reproducibly results in a predetermined, measurable amount of apoptosis in the segment; at least a negative control segment of a tissue which has not been subjected to the treatment and at least a positive control segment of the tissue which has been subjected to a level of the treatment that reproducibly results in a maximum amount of apoptosis obtainable in the segment as a result of the treatment; and one or more intermediate control segments of the tissue which have been subjected to a level of the treatment that reproducibly results in a predetermined amount of apoptosis intermediate between that of the negative control segment and that of the positive control segment.