Patent ID: 7468380
Filing Date: 2008-12-23
Classification: A61K,A61P,C07D

Abstract:
1. A compound represented by the general formula: or a salt or hydrate thereof, wherein: X X Y represents an oxygen atom, a sulfur atom, a sulfinyl group, a sulfonyl group, or a group represented by the formula —NR R (wherein Y A1 and Y A2 each independently represents a group represented by the formula -A 10 -A 11 -A 12 (wherein A 10 represents a single bond or an optionally substituted C1-6 alkylene; A 11 represents a single bond, an oxygen atom, a carbonyl group or a sulfonyl group; and A 12 represents a hydrogen atom, a C 1-6 alkyl group, a C 2-6 alkenyl group, a C 2-6 alkynyl group, a C 3-8 cycloalkyl group, a C 6-10 aryl group, a 5- to 10-membered heteroaryl group, a group represented by the formula —NR A10 R A11 , a group represented by the formula —OR A12 (wherein R A10 , R A11 and R A12 each independently represents a hydrogen atom, a C1-6 alkyl group or C 3-8 cycloalkyl group) or a group represented by the formula: (wherein e represents 1 or 2; Z represents an oxygen atom, a group represented by the formula —CR X7 R X8 — or a group represented by the formula —NR X9 —; R X7 , R X8 and R X9 each independently represents a hydrogen atom, a hydroxyl group or a C 1-6 alkyl group)); and Y A3 represents a hydrogen atom or an optionally substituted C 1-6 alkyl group) or a group represented by the formula: (wherein T1 represents an optionally substituted 5- to 10-membered aromatic heterocycle which may have X in the ring or an optionally substituted 3- to 10-membered heterocycle which may have X in the ring); R R R R R R (wherein T2 represents an optionally substituted 5- to 10-membered aromatic heterocycle or an optionally substituted 3- to 10-membered heterocycle); R R R X represents an oxygen atom, a sulfur atom, a carbonyl group, a sulfonyl group, a group represented by the formula —CR (wherein a represents 1 or 2))).