Patent ID: 8957059
Filing Date: 2015-02-17
Classification: A61K,A61P,C07D

Abstract:
1. A method of treating a subject suffering from or diagnosed with a disease, disorder, or condition selected from the group consisting of: sleep disorders, depression/anxiety, generalized anxiety disorder, schizophrenia, bipolar disorders, cognitive disorders, mild cognitive impairment, Alzheimer's disease, Parkinson's disease, psychotic disorders, phobic disorders, obsessive-compulsive disorder, mood disorders, post-traumatic stress disorder, migraine, pain, eating disorders, obesity, sexual dysfunction, metabolic disturbances, hormonal imbalance, hot flushes associated with menopause, alcohol abuse, drug abuse, drug addiction, alcohol addiction, nausea, inflammation, centrally mediated hypertension, sleep/wake disturbances, jetlag, and circadian rhythm abnormalities, comprising administering to the subject an effective amount of at least one compound of Formulae (I) or (II): wherein R m is 1, n is 1 or 2; L is absent or O; R R o is 0, 1, or 2; and each R or a pharmaceutically acceptable salt of a compound of Formulae (I) or (II), a pharmaceutically acceptable prodrug of a compound of Formulae (I) or (II), or a pharmaceutically active metabolite of a compound of Formulae (I) or (II).