Patent ID: 6686370
Filing Date: 2004-02-03
Classification: A61K,A61P,C07D,Y10S

Abstract:
A compound selected from the group consisting of8-[1-(1,2,3,4tetrahydronaphthyl)-1-carbonyl-methyl]-1-phenyl-1,3,8-triazospiro[4.5]decan-4-one; 8-[1-(1,2,3,4tetrahydronaphthyl)-1-carbonyl-methyl]-3[1-oxo-ethyl]-1-phenyl-1,3,8-triazospiro[4.5]decan-4-one; 8-[1-benzodioxane-1-carbonyl-methyl]-1-phenyl-1,3,8-triazospiro[4.5]decan-4-one; 8-[1-(2-quinoline-1-carbonyl-methyl]-1-phenyl-1,3,8-triazospiro[4.5]decan-4-one; 8-[1-dibenzocycloheptyl-1-carbonyl-methyl]-1-phenyl-1,3,8-triazospiro[4.5]decan-4-one; 8-[1-(2-pyridyl)-1-carbonyl-methyl-1-phenyl-1,3,8-triazospiro[4.5]decan-4-one; 8-[4-phenyl-&agr;-carbonyl-benzyl]-1-phenyl-1,3,8-triazospiro[4.5]decan-4-one; 8-[4-benzyloxy-&agr;-carbonyl-benzyl]-1-phenyl-1,3,8-triazospiro[4.5]decan-4-one; 8-[1-(2-naphthyl)-1-carbonyl-methyl]-1-phenyl-1,3,8-triazospiro[4.5]decan-4-one; 8-[4-trifluoromethyl-&agr;-carbonyl-benzyl]-1-phenyl-1,3,8-triazospiro[4.5]decan-4-one; 8-[1-benzylpiperazine-1-carbonyl-methyl]-1-phenyl-1,3,8-triazospiro[4.5]decan-4-one; 8-[1-decalin-1-carbonyl-methyl]-1-phenyl-1,3,8-triazospiro[4.5]decan-4-one; 8-[&agr;-carbonyl-furfuryl]-1-phenyl-1,3,8-triazospiro[4.5]decan-4-one; and pharmaceutically acceptable salts thereof.