Patent ID: 8697435
Filing Date: 2014-04-15
Classification: G01N,Y10S

Abstract:
1. A system for sample preparation and analyte detection, the system comprising: (A) a fluid having a sample containing a target analyte, first type particles being responsive to a force field, and second type particles capable of generating a signal, the first and second type particles having binding moieties such that the first and second type particles link via the target analyte to form a multiple-particle complex; (B) a cartridge having a capture spot within a fluidic channel, the capture spot including binding moieties for a specific particle defining one of the first and second type particles; and (C) a force field generator for sequentially moving a first portion of the fluid responsive to the force field to a location separate from the capture spot, the first portion to the capture spot such that the at least one multiple-particle complex is captured via the specific particle, and an uncaptured portion of the first portion away from the capture spot; and (D) a fluid replacement for removing a second portion of the fluid not responsive to the force field.