Patent ID: 6777553
Filing Date: 2004-08-17
Classification: C07D

Abstract:
A one step process for the preparation of bis-(substituted4-quinolyl) disulphide of the formula 1 wherein R1 is selected from the group consisting of trifluoro, trichloro, cyano, or substituted amide; R2 is selected from the group consisting of alkyl, alkoxy, halogen, or alkylamino; comprising reacting a substituted 4-haloquinoline and a sodium, potassium, or ammonium salt of dithiocarbamic acid of the formulaR3HNCSSZ wherein R3 is selected from the group consisting of (C1-C4) alkyl or aryl; and Z is selected from the group consisting of Na, K, or NH4; in an organic solvent to obtain said bis-(substituted-4-quinolyl) disulphide of the formula 1 and a disubstituted thiourea of the formula 2