Patent ID: 8293705
Filing Date: 2012-10-23
Classification: A61K,A61P,C07K,C12N

Abstract:
1. A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: R R R each R is independently hydrogen, optionally substituted C R R or a natural or unnatural amino acid side-chain group; each R R R R or R 4 and R z are taken together with their intervening atoms to form an optionally substituted, saturated or unsaturated 16-22 membered ring having 2-6 heteroatoms independently selected from nitrogen, oxygen, or sulfur; each occurrence of R R m is an integer from 0 to 4, inclusive; s is an integer from 0 to 4, inclusive; t is an integer from 0 to 4, inclusive; wherein the sum of s and t is non-zero.