Patent ID: 6476047
Filing Date: 2002-11-05
Classification: A61K,C07D

Abstract:
A compound of the following formula I, or a pharmaceutically acceptable salt thereof: wherein A is benzo, R1, R2 and R3 independently of one another denote H, OH, C1-C5 alkyl, C1-C5 alkoxy, or â€”Oâ€”(CH2)1-5â€”OCH3, or R2 and R3 together form the group â€”Oâ€”CH2â€”Oâ€”, R4 and R5 independently of one another denote H, or C1-C5 alkyl or together with the atom to which they are bonded form a C3-C7 ring; R6 denotes C1-C12 alkyl, or denotes a phenyl or benzyl group each substituted by the groups R7 and R8, wherein R7 and R8 independently of one another denote hydrogen, halogen, C1-C5 alkyl, C1-C5 alkoxy or C1-C5 fluoroalkyl group; Z denotes O, S or an NHCOâ€” group or, if at least one of the groups R4 and R5 is other than hydrogen, Z may also denote a single bond; with the proviso that when Z is O or S, then R6 cannot be C1-C12 alkyl, or phenyl substituted by the groups R6 and R8, wherein R7 and R8 independently of one another denote hydrogen or halogen.