Patent ID: 7176178
Filing Date: 2007-02-13
Classification: A61K,A61P,C12N,Y10S

Abstract:
1. A method of targeting one or more components to the nucleus of a lymphocyte or epithelial cell, said method comprising administering a nuclear delivery construct to said lymphocyte or epithelial cell, wherein said nuclear delivery construct is comprised of: (i) a polypeptide comprising the sequence as set forth in SEQ ID NO: 6, amino acids 42 to 376 of SEQ ID NO: 6, amino acids 42 to 346 of SEQ ID NO: 6 or amino acids 42 to 326 of SEQ ID NO: 6; and conjugated or fused therewith; (ii) said one or more components whose targeting to the nucleus of the lymphocyte or epithelial cell is desired.