Patent ID: 7544503
Filing Date: 2009-06-09
Classification: A61B,G01J,G01N

Abstract:
1. A spectroscopic analysis apparatus for non-invasive in vivo analysis of blood comprising: an excitation system for emitting an excitation beam to excite a target region containing a blood vessel, said excitation system configured to emit an excitation beam having a predetermined polarization orientation; a detection system for detecting scattered radiation from blood in the blood vessel in the tar et re ion generated b the excitation beam to obtain a Raman signal; a signal processing system for extracting at least one predetermined pH sensitive signal portion from said Raman signal and for determining a depolarization ratio from said at least one pH sensitive signal portion of said Raman signal and for determining the pH value of the blood in the target region from said depolarization ratio by use of a relationship between pH value and depolarization ratio of vibrations of one or more molecules at excitation wavelengths included in said at least one pH sensitive signal portions; a monitoring system for imaging the target region; and a focusing system for focusing the excitation system, the detection system and the monitoring system on the target region.