Patent ID: 8802125
Filing Date: 2014-08-12
Classification: A61K,A61L,A61P

Abstract:
1. A biocompatible delayed release system comprising: (i) a polycaprolactone polymer matrix, wherein the biocompatible delayed release system comprises about 30% to 90% by weight of polymer matrix, and the polymer matrix formulated as a lamellar charged structure; and (ii) an intercalation compound dispersed inside the polycaprolactone polymer matrix, wherein the intercalation compound comprises: wherein the intercalated combination of the inorganic hydrotalcyte component and of the diclofenac constitutes the intercalation compound, and the diclofenac is present in a quantity ranging from between about 1% to 50% by weight as compared to the inorganic hydrotalcyte component, and the concentration of the intercalation compound in the biocompatible delayed release system is between about 1% and 10%, and wherein the delayed release system has a two stage release profile.