Patent ID: 7994153
Filing Date: 2011-08-09
Classification: A61K,A61P,A61Q

Abstract:
1. A method for improving melasma, comprising applying, to a melasma lesion, an externally-applied medical or cosmetic composition comprising an adenosine monophosphate or a salt thereof, a polyglyceryl fatty acid ester, an alkanoyl lactic acid or a salt thereof, an acrylic acid-alkyl methacrylate copolymer, water, an oil, a polyhydric alcohol, and a lower alcohol having 1 to 6 carbons; wherein the proportion of the adenosine monophosphate or a salt thereof is 1 to 10 weight percent based on the total amount of the composition; wherein the adenosine monophosphate is at least one member selected from the group consisting of adenosine 2′-monophosphate, adenosine 3′-monophosphate, and adenosine 5′-monophosphate; and wherein the composition is formulated into an oil-in-water (O/W)-type emulsion.