Patent ID: 6617338
Filing Date: 2003-09-09
Classification: A61K,A61P

Abstract:
Orally administrable administrable acid stable anti-ulcer benzimidazole compound of the formula I: wherein R6=H or CH3, X=â€”OCOCH2COOâ€”, or â€”CONHCH2NHCOâ€”, R7=H, CH3, C2H5 or CONH2, Y=OH or NH,, E=â€”COOâ€”, R is benzimidazole moiety of the formula IIA: wherein each of R1, R2, R3, R4, R5=H, C1-12 alkyl, C1-8 (un)substituted aryl, C1-8 alkoxy, C6-12 aryloxy, C1-5 alkoxy carbonyl, C6-12 aryloxy carbonyl, C1-5 alkoxy alkyl, C6-12 alkoxyaryl, C1-5, haloalkyl, C1-5 alkyl, C1-5 haloalkoxy alkyl or C6-12 aryl thioethers, (un)substituted amines or diamines, (un)substituted amides, halo, cyano, nitro, carboxylic acid or carbocyclic or enantiomers thereof; or a pharmaceutically acceptable acid addition salt thereof.