Patent ID: 6299583
Filing Date: 2001-10-09
Classification: A61B,A61M

Abstract:
A system for determining hemodynamic parameters of a cardiovascular system said cardiovascular system circulating blood within a bloodstream extending to peripheral regions of a body comprising:a source of analyte-containing fluid biocompatible with and metabolizable within said body and said fluid having a predetermined analyte concentration;fluid flow control apparatus coupled with said source of analyte containing fluid and controllable to provide a flow of said analyte containing fluid at a predetermined mass flow rate at an outlet for an infusion interval having a time of delivery;a delivery assembly having a delivery channel with an input coupled in fluid flow communication with said fluid flow control apparatus and an output positioned to express said flow of analyte-containing fluid within said bloodstream for dilutional movement therewith;an analyte concentration sensor positioned within said bloodstream, responsive to analyte within said bloodstream and controllable to provide sensor outputs corresponding with the sensed concentration of said analyte; anda controller coupled in controlling relationship with said fluid flow control apparatus and said analyte concentration sensor, responsive to control said analyte concentration sensor to provide said sensor outputs and to derive corresponding analyte concentration values, responsive to control said fluid flow control apparatus to effect provision of said flow of said analyte-containing fluid at said outlet for said infusion interval, responsive to a sequence of said analyte concentration values, as time associated analyte concentration values, said sequence exhibiting time associated concentration values rising in value toward a peak value and descending in value therefrom, responsive to correlate said time associated concentration values, said predetermined mass flow rate, said predetermined analyte concentration and said infusion interval to derive an output signal representing a value corresponding with a select said hemodynamic parameter; anda readout responsive to said output signal for providing a perceptible output corresponding therewith.