Patent ID: 7026461
Filing Date: 2006-04-11
Classification: A01K,A61K,A61P,C07K,C12N,G01N

Abstract:
1. A radiolabeled compound of the following structural formula that serves as a substrate for a mutant form of a wild-type kinase, wherein the compound does not serve as a substrate for the wild-type kinase, wherein X is selected from the group consisting of —NH—O-alkyl, —NH—O-cycloalkyl, —NH—O-cycloalkyl, —NH—C(O)-alkyl, —NH-alkylaryl, —NH—O-alkylaryl, and —N-heterocycloalkyl where the nitrogen atom is part of the heterocycloalkyl ring and wherein at least one of the phosphorus atoms is radioactive.