Patent ID: 8957091
Filing Date: 2015-02-17
Classification: G01N

Abstract:
1. A method of activating the Hedgehog signaling pathway, comprising bringing a Smoothened receptor and at least one compound of general formula (I) below into contact: in which: X, in the ortho, meta or para position, represents —H, —OH, —NH R W represents —H, —OH, —NH R a hydrogen atom; or an alkyl group consisting of a linear or branched carbon-based chain having from 1 to 10 carbon atoms, optionally unsaturated with one or more double or triple bonds, and optionally substituted with one or more heteroatoms, with one or more halogen atoms or with one or more aryl or heteroaryl groups; or a cycloalkyl having from 3 to 8 carbon atoms, optionally substituted with an alkyl radical consisting of a linear or branched carbon-based chain having from 1 to 10 carbon atoms or an alkoxy radical; R wherein R