Patent ID: 8962268
Filing Date: 2015-02-24
Classification: C12Q,G01N

Abstract:
1. A method for determining the survival prognosis of a patient suffering from non-small cell lung cancer, comprising the steps of: (a) measuring kinase activity of a sample, obtained from the non-small cell lung tumor from said patient, by contacting said sample in the presence and in the absence of a protein kinase inhibitor with at least the peptide markers consisting of SEQ ID NO: 1 to 19, and obtaining phosphorylation of phosphorylation sites present in said sequences, thereby providing a phosphorylation profile of said sample in the presence of a protein kinase inhibitor and a phosphorylation profile of said sample in the absence of a protein kinase inhibitor, (b) determining from said phosphorylation profiles in the presence and in the absence of a protein kinase inhibitor the differential phosphorylation level, said differential phosphorylation level indicating the survival prognosis of said patient.