Patent ID: 6365604
Filing Date: 2002-04-02
Classification: A61P,C07D

Abstract:
A compound of the formula (I) wherein R1 is benzothienyl, benzofuranyl, naphthyl, substituted-thienyl or substituted-furanyl, wherein the benzothienyl, benzofuranyl or naphthyl moiety is unsubstituted or substituted by one or more substituents selected from halogen, C1-6-alkyl, C3-6-cycloalkyl, C1-6-alkoxy and C2-6-alkenyl and wherein the thienyl or furanyl moiety is substituted by one or more substituents selected from halogen, C1-6-alkyl, C3-6-cycloalkyl, C1-6-alkoxy and C2-6-alkenyl;R2 is substituted-phenyl or substituted-thienyl, wherein the phenyl or thienyl moiety is substituted by one or more substitutents selected from C1-6-alkyl and halogen; R3 is â€”(CH2)mXCONR4R5; R4 and R5 together with the nitrogen atom to which they are attached form a 4- or 5-membered heterocyclic ring that is unsubstituted or substituted by one or more substituents selected from halogen, C1-6-alkyl, C1-6-cycloalkyl, C1-6-alkoxy and C2-6-alkenyl; X is a bond; m is the integer 1, 2, 3 or 4; or a pharmaceutically acceptable salt thereof or a solvate thereof.