Patent ID: 8530169
Filing Date: 2013-09-10
Classification: A61P,G01N,Y10T

Abstract:
1. A method for detecting and characterizing binding between an isolated oligosaccharide and a binding partner, comprising the steps of: contacting an isolated oligosaccharide with a binding partner under conditions that allow binding of the oligosaccharide with the binding partner to form an oligosaccharide-binding partner complex; detecting the presence of the oligosaccharide-binding partner complex by subjecting the oligosaccharide-binding partner complex to a gel mobility shift assay having a native gel; and characterizing the binding partner that binds to the oligosaccharide in the oligosaccharide-binding partner complex, wherein the isolated oligosaccharide comprises heparan sulfate, chondroitin sulfate, dermatan sulfate, and/or keratan sulfate.