Patent ID: 8658093
Filing Date: 2014-02-25
Classification: B01L,G01N

Abstract:
1. An apparatus comprising: a support having an upper surface comprising a plurality of discrete analyte binding areas arranged in a spaced relationship, wherein each of the discrete analyte binding areas comprises an immobilized macromolecule which comprises one or more ligand moieties which specifically bind to a target analyte and; a cover spaced from the upper surface of the support and forming a flow channel therebetween, the cover having a first surface facing toward the support and a second surface facing away from the support; wherein at least one discrete area comprises an immobilized macromolecule which comprises a plurality of carbohydrate ligands, wherein the carbohydrate ligands comprise a plurality of lectin moieties, wherein the immobilized macromolecule which comprises a plurality of lectin moieties comprises one or more pendent groups of the formula: wherein “MACROMOLECULE” represents the immobilized macromolecule, “PEG” is a telechelic poly(ethylene oxide) moiety, “Lectin” is a lectin moiety and L 1 , L 2 and L 3 are each, independently, a covalent bond or a linking group.