Patent ID: 6562819
Filing Date: 2003-05-13
Classification: A61P,C07D

Abstract:
A compound of the formula: wherein R1 is a terminally substituted normal alkyl having from 1 to 7 carbon atoms, a terminally substituted alkenyl having from 2 to 7 carbon atoms, a terminally substituted ether having from 2 to 6 carbon atoms, a terminally substituted secondary amine having from 2 to 6 carbon atoms, or substituted aryl having less than 8 carbons, where the terminal group is SO2R or COOR, where R is an alkylamino, where the alkyl group has from 1 to 4 carbon atoms and the amino is NH2 or a substituted amino where the substituents on the amino have 1 to 6 carbon atoms, one of which can be replaced by an oxygen atom or nitrogen atom; R2 is hydrogen, alkyl, cycloalkyl, heterocyclic alkyl, alkenyl, halogen, NO, amino, substituted amino or aralkyl having from 1 to 7 carbon atoms; R3 and R4 are independently H, SH, OH, alkyl, cycloalkyl, heterocyclic alkyl, alkenyl, aryl, alkylcarboxyl, or aralkyl having from 1 to 7 carbon atoms, OH or O-alkyl having from 1 to 5 carbon atoms; R5 is H, alkyl, cycloalkyl, heterocyclic alkyl, alkenyl, aryl or aralkyl having from 1 to 7 carbon atoms, OH, or O-alkyl having from 1 to 5 carbon atoms; and R6 is H, NO, amino, or substituted amino, or a salt thereof.