Patent ID: 7285637
Filing Date: 2007-10-23
Classification: A61L,D01D,D01F,D04H

Abstract:
1. A method for producing non-woven silk fiber fabrics comprising the following steps: a) preparing silk fibroin solution by adding degummed silk fibroin to formic acid solution having a concentration of formic acid from 88% to 99% by weight; b) mixing the solution to facilitate breaking of the disulfide bonds between heavy (350 kDa) and light (27 kDa) chains of silk fibroin in order to obtain the production of light and heavy chain fragments, wherein said chain fragments serve as a specific cellular recognition sites for promoting the attachment and growth of cells; c) removing the formic acid to obtain non-woven silk fiber fabrics; and d) washing the obtained non-woven silk fiber fabrics.