Patent ID: 7135469
Filing Date: 2006-11-14
Classification: A61P,C07D

Abstract:
1. A compound of formula I: or a stereoisomer or pharmaceutically acceptable salt thereof, wherein; G is a group of Formula IIa: alternatively, ring D is absent and ring E is phenyl, and ring E is substituted with 1–3 R; R is selected from H, C A is 2–8 membered linear chain consisting of: carbon atoms, 0–2 carbonyl groups, and 0–3 heteroatoms selected from O, N, and S(O) B is selected from OR provided that the R 4d shown is other than OH; B B B B B Q alternatively, Q ring Q is a 5–8 membered ring consisting of, in addition to the Q ring Q alternatively, ring Q ring Q Q ring Q Y is CY R alternatively, when two R R R R alternatively, NR R R R alternatively, NR R R alternatively, CR alternatively, NR alternatively, when B alternatively, when B alternatively, when B R R alternatively, NR R R R R R R alternatively, when R R R R R R R R R R R alternatively, R R n, at each occurrence, is selected from 0, 1, 2, and 3; p, at each occurrence, is selected from 0, 1, and 2; r, at each occurrence, is selected from 0, 1, 2, 3, 4, 5, and 6; and t, at each occurrence, is selected from 0, 1, 2, and 3.