Patent ID: 6414147
Filing Date: 2002-07-02
Classification: A61P,C07D

Abstract:
A compound of the formula: or a pharmaceutically acceptable non-toxic salt thereof wherein:W is oxygen or sulfur; X is lower alkyl optionally mono-, di- or trisubstituted with C2-C6 alkenyl, C2-C6 alkynyl, lower alkoxy, halogen, hydroxy, trifluoromethyl, aryl, heteroaryl, C3-C7 cycloalkyl, tetrahydrofuranyl, CO2R where R is hydrogen or lower alkyl, or aryl or heteroaryl, each of which is optionally substituted with halogen or lower alkoxy; or X is aryl or heteroaryl each of which is optionally substituted with up to three groups selected from halogen and lower alkoxy; Y is hydrogen or lower alkyl; Z is C3-C6 alkyl; and T is aryl or heteroaryl optionally substituted with up to 5 groups independently selected from halogen, lower alkyl or lower alkoxy, each of which is optionally substituted with lower alkoxy, halogen or aryl optionally substituted with lower alkyl or lower alkoxy.