Patent ID: 8501797
Filing Date: 2013-08-06
Classification: A61P,C07D

Abstract:
1. A compound having the structure I wherein HET-1 is a heteroaromatic group of formula II containing from 2 to 4 nitrogen atoms: wherein Y can be N or CH, Z can be N or C, and wherein HET-1 may optionally be substituted with up to three R 7 , R 8 and R 9 substituents individually selected from hydrogen, C 1 - C 6 alkyl; halogen; cyano, halo(C 1 -C 6 )alkyl; aryl, alkoxy and C 1 -C 6 hydroxyalkyl, and wherein * denotes the attachment point, Q is phenyl, optionally substituted with one, two or three R -L- is a linker selected from —S—CH R and pharmaceutically acceptable salts thereof, provided that the compound is not 2-(5-phenyl-1H-imidazol -2-ylmethylsulfanyl)-1H-benzoimidazole or 2-(5-phenyl-1H- imidazol-2-sulfanyl-methyl)-1H-benzoimidazole.