Patent ID: 6468502
Filing Date: 2002-10-22
Classification: A61K,A61P,B65D,C07C,C07D

Abstract:
A perfluoroalkyl-containing compound of formula IRFâ€”Lâ€”Aâ€ƒâ€ƒI in whichRF is a perfluorinated, straight-chain or branched carbon chain with formula â€”CnF2nX, in which X represents a terminal, fluorine, chlorine, bromine, iodine or hydrogen atom, and n stands for numbers 4-30, L means a direct bond, a methylene group, an â€”NHCO group, a group â€ƒwhereby p means numbers 0 to 10, q and u, independently of one another, mean numbers 0 or 1 and R1 is a hydrogen atom, a methyl group, a â€”CH2â€”OH group, a â€”CH2â€”CO2H group or a C2-C15 chain, which optionally is interrupted by 1 to 3 oxygen atoms, 1 to 2>CO groups or an optionally substituted aryl group and/or is substituted with 1 to 4 hydroxyl, groups, 1 to 2 C1-C4 alkoxy groups, 1 to 2 carboxy groups, a group â€”SO3H, or L is a straight-chain, branched, saturated or unsaturated C2-C30carbon chain, which optionally contains 1 to 10 oxygen atoms, 1 to 3â€”NR1 groups, 1 to 2 sulfur atoms, a piperazine, a â€”CONR1 group, an â€”SO2 group, an â€”NR1â€”CO2 group, 1 to 2 â€”CO groups, a group â€”COâ€”Nâ€”Tâ€”N(R1)â€”SO2â€”RF or 1 to 2 optionally substituted aryls and/or is interrupted by these groups and/or is optionally substituted with 1 to 3 â€”OR1 groups, 1 to 2 oxo groups, 1 to 2 â€”NHâ€”COR1 groups, 1 to 2 â€”CONHR1 groups, 1 to 2 â€”(CH2)pâ€”CO2H groups, 1 to 2 groups of â€”(CH2)pâ€”(O)qâ€”CH2CH2â€”RF, whereby R1, RF and p and q have the above-indicated meanings, and T means a C2-C10 chain, which optionally is interrupted by 1 to 2 oxygen atoms or 1 to 2 â€”NHCO groups, A stands for a complexing agent or metal complex or their salts of organic and/or inorganic bases or amino acids or amino acid amides, specifically for a complexing agent or complex of general formula VI Z1 independently of one another, mean a hydrogen atom or a metal ion equivalent of atomic numbers 21-29, 39, 42, 44 or 57-83. orA stands for a complexing agent or complex of formula VII Z Y means â€”OZ1 or orA stands for a complexing agent or complex of formula VIII R3 has the meaning of R1 or means â€”(CH2)mâ€”Lâ€”RF, whereby m is 0, 1 or 2 and L and RF have the above-mentioned meaning, and R2 has the above-mentioned meaning of R1, orA stands for a complexing agent or complex of general formula IX â€ƒin which R3 and Z1 have the above-mentioned meanings, orA stands for a complexing agent or complex of formula X â€ƒin which R3 and Z1 have the above-mentioned meanings, orA stands for a complexing agent or complex of formula XI â€ƒin which Z1 has the above-mentioned meaning and R2 has the meaning of R1.