Patent ID: 8632787
Filing Date: 2014-01-21
Classification: A61K,A61P,C07K

Abstract:
1. A method of treating a patient having acute myeloid leukemia, which comprises (a) administering to said patient a therapeutically effective amount of cytarabine and from about 5 mg per day to about 25 mg per day of 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione having the formula: or a pharmaceutically acceptable salt, or solvate thereof wherein the 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione is administered for 21 days followed by a period of rest; and (b) repeating step (a).