Patent ID: 7456953
Filing Date: 2008-11-25
Classification: G01N,G02B

Abstract:
1. An apparatus for analyzing a sample containing a target analyte comprising: a sample including a target analyte, the sample having a analyte index of refraction; a first layer adjacent at least one side of the sample, the first layer including a coupling zone followed by a thicker region, the first layer having first index of refraction greater than the analyte index of refraction; a second layer adjacent at least a second side of the sample, the second layer having a second index of refraction, the second index of refraction greater than the analyte index of refraction; the coupling zone to receive light from a light source and generate an approximately homogenous anti-resonant guided optical mode in the sample; and, an analyzing system to detect the interaction of the light propagating in the sample with the target analyte.