Patent ID: 8008310
Filing Date: 2011-08-30
Classification: A61P,C07D

Abstract:
1. A compound according to formula (I): in which: R1 is selected from the group consisting of (C1-C6)alkyl, (C1-C6)alkyl(C3-C7)cycloalkyl, CH2COR3, phenyl, and phenyl substituted with one or more substituents selected from the group consisting hydroxyl, halogen, and (C1-C6)alkyl; R3 is a hydroxyl, (C1-C4)alkoxy, amino, (C1-C4)alkylamino or di(C1-C4)alkylamino group; Ar1 is a radical selected from the group consisting of: in which X is O or S; Y is CH R4 and R5 are each, independently of one another, a substituent selected from the group consisting of H, (C1-C4)alkyl, (C1-C6)alkyl(C3 -C7)cycloalky, (C3 -C7)cycloalkyl, C(═NH)NH or R4 and R5, together with the nitrogen atom to which they are attached, constitute an azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl or morpholinyl radical, said radical being unsubstituted or substituted one or more times with a (C1-C6)alkyl, (C1-C4)alkyl-OH or COO(C1-C6)alkyl group; Ar2 is a phenyl group which is unsubstituted or substituted from 1 to 5 times with the same or different substituents selected from the group consisting of a halogen atom, a (C1-C4)alkyl group, a trifluoromethyl group, and a (C1-C4)alkoxy group; n represents 1, 2 or 3; or a pharmaceutically acceptable salt thereof.