Patent ID: 6342492
Filing Date: 2002-01-29
Classification: A61K,A61P

Abstract:
A pharmaceutical composition having pharmacological activity comprising a compound of formula I and a pharmaceutically effective carrier: whereinW is a bridge carbon which has a polar or non-polar side group, X and Y independently are an aromatic group, an alkyl group, a sulfonyl group or a carbonyl group, said aromatic group is selected from the group consisting of Ar, Ar sulfonyl, Ar carboxy and Ar alkyl, where Ar is an aromatic cyclic or aromatic heterocyclic ring having from five to seven members, said alkyl groups having from one to ten carbons, X and Y are not both an alkyl group so that at least one of X and Y is an aromatic group, a sulfonyl group or a carbonyl group, Z is a group listed for X and Y, a fused aryl moiety having from seven to ten carbons or hydrogen, a, d and e independently are a number from zero to 10, c and b independently are a number from one to 10, and the compound is cyclic or acyclic and includes sufficient hydrogens for a stable molecule.