Patent ID: 7399626
Filing Date: 2008-07-15
Classification: C12N,C12Y

Abstract:
1. An isolated C5-epimerase polypeptide that has glucuronyl C5-epimerase activity that converts D-glucuronic acid to L-iduronic acid, or an enzymatically active fragment thereof that has said C5-epimerase activity, said polypeptide comprising an amino acid sequence at least 97% identical to sequence (n) below and at least 97% identical to at least one of sequences (a) to (m), or (o) below: (a) amino acids 1 to 118 of (b) amino acids 1 to 119 of (c) amino acids 1 to 120 of (d) amino acids 1 to 121 of (e) amino acids 119 to 618 of (f) amino acids 120 to 618 of (g) amino acids 121 to 618 of (h) amino acids 122 to 618 of (i) amino acids 34 to 147 of (j) amino acids 35 to 154 of (k) amino acids 34 to 154 of (l) amino acids 1 to 154 of (m) amino acids 155-618 of (n) amino acids 1-618 of (o) amino acids 34-618 of