Patent ID: 6586202
Filing Date: 2003-07-01
Classification: C12N,C12P

Abstract:
An isolated DNA sequence comprising a DNA sequence that hybridizes to SEQ ID NO:1 under the following conditions: hybridization in 50% formamide (v/v), 2% blocking agent, 5XSSC, 0.1% N-lauroylsarcosine (w/v), and 0.1% SDS at 42Â° C. overnight followed by two washes for 5 minutes each in 2XSSC and 0.1% SDS at room temperature followed by two additional washes of 15 minutes each in 0.1XSSC and 0.1% SDS at 68Â° C., wherein the DNA sequence encodes an amino acid sequence having 3-hydroxy-3-methylglutaryl-CoA synthase (HMG-CoA synthase) activity.