Patent ID: 8153380
Filing Date: 2012-04-10
Classification: C12Q,G01N

Abstract:
1. A method of predicting clinical outcome for a human subject diagnosed with colorectal cancer following surgical resection of said cancer, comprising: determining a normalized expression level of an RNA transcript of INHBA, or an expression product thereof, in a biological sample comprising cancer cells obtained from said human subject, and; predicting the likelihood of a positive clinical outcome for said human subject by comparing said normalized expression level of an RNA transcript of INHBA, or an expression product thereof, to gene expression data obtained from colorectal cancer reference samples comprising cancer cells derived from patients with colorectal cancer, wherein said patients comprise patients with Dukes C (stage III) colorectal cancer and wherein said normalized expression level of an RNA transcript of INHBA, or an expression product thereof, is negatively correlated with an increased likelihood of a positive clinical outcome.