Patent ID: 7669597
Filing Date: 2010-03-02
Classification: A61F,A61J,A61M

Abstract:
1. A dosage form for delivery of a pharmaceutical composition, the dosage form comprising: a first dosage blister chamber containing a first component of the pharmaceutical composition; a second dosage blister chamber containing a second component of the pharmaceutical composition; and a dispensing blister chamber comprising a piercable membrane; wherein the dosage form further comprises: a vapor barrier membrane separating the first dosage blister chamber from the second dosage blister chamber; a delamination seal, wherein the delamination seal prevents mixing of the contents of the dosage blister chambers with the dispensing chamber, wherein the dispensing blister chamber contains a piercing device, wherein the piercing device is a substantially hollow, elongate member with a base end and a piercing tip opposite the base end and providing a discharge nozzle; the piercing device comprising one or more inlet openings on or near the base end and an internal conduit providing fluid communication between the one or more inlet ports and the discharge nozzle; and wherein the surface of the internal conduit comprises structural features to control the spray pattern and droplet size of a fluid forced through the piercing device.