Patent ID: 6677337
Filing Date: 2004-01-13
Classification: A61K,A61P,C07D

Abstract:
A compound, or all enantiomeric and diasteriomeric forms or pharmaceutically acceptable salts thereof, said compound having the formula: wherein R is: a) â€”O[CH2]nR4; or b) â€”N R5aR5b; R4 is substituted or unsubstituted C1-C10 linear, branched, or cyclic alkyl; substituted or unsubstituted aryl; substituted or unsubstituted heterocyclic; or substituted or unsubstituted heteroaryl; the index n is from 0 to 5; R5a and R5b are each independently: a) hydrogen; or b) â€”[C(R6aR6b)]mR7; each R6a and R6b is independently: i) hydrogen; ii) â€”OR8; iii) â€”N(R8)2; iv) â€”CO2R8; v) â€”CON(R8)2; vi) substituted or unsubstituted C1-C4 linear, branched, or cyclic alkyl; vii) and mixtures thereof; R7 is i) hydrogen; ii) substituted or unsubstituted C1-C6 linear, branched, or cyclic alkyl; iii) substituted or unsubstituted heterocyclic; iv) substituted or unsubstituted aryl; v) substituted or unsubstituted heteroaryl; vi) â€”OR8; vii) â€”N(R8)2; viii) â€”CO2R8; and ix) â€”CON(R8)2; R8 is hydrogen, a water-soluble cation, C1-C4 alkyl, or substituted or unsubstituted aryl; the index m is from 0 to 5; R1 is substituted phenyl; each R2 and R3 unit is independently selected from the group consisting of: a) hydrogen; and b) substituted or unsubstituted C1-C10 hydrocarbyl selected from the group consisting of: i) C1-C10 linear, branched or cyclic alkyl; ii) C6-C10 aryl; iii) C1-C10 heterocyclic; iv) C1-C10 heteroaryl.