Patent ID: 6072068
Filing Date: 2000-06-06
Classification: A61P,C07J

Abstract:
A compound of formula I ##STR3## wherein R.sub.1 is C.sub.1-6 alkyl, C.sub.3-6 cycloalkyl, C.sub.1-6 alkoxy, triflate, pyridyl or phenyl where the phenyl moiety is optionally substituted by one or more substituents selected from cyano, halogen and C.sub.1-4 alkyl;R.sub.2 is hydrogen, C.sub.1-6 alkyl, 1-oxo-C.sub.1-6 alkyl or carboxy-1-oxo-C.sub.1-6 alkyl;R.sub.3 is hydrogen, halogen or C.sub.1-6 alkyl optionally substituted by one or more substituents selected form C.sub.1-6 alkoxy and halogen;R.sub.4 is hydrogen, C.sub.1-6 alkyl, 1-oxo-C.sub.1-6 alkyl or carboxy-1-oxo-C.sub.1-6 alkyl; andX is (H,OH), O or NOH;or a pharmaceutically acceptable salt or solvate thereof.