Patent ID: 6811768
Filing Date: 2004-11-02
Classification: A61K,A61P

Abstract:
A method for decreasing or preventing non-pulmonary inflammation in a mammal, comprising the steps of:(a) identifying a mammal which has existing inflammation or is at risk for developing inflammation in a non-pulmonary tissue; (b) causing the mammal to inhale a therapeutically effective amount of gaseous nitric oxide sufficient to diminish the ability of the mammal's leukocytes or platelets to become activated in a manner that contributes to an inflammation process in the non-pulmonary tissue, thereby decreasing or preventing non-pulmonary inflammation in the mammal; and (c) immediately before, during, or after the inhalation of nitric oxide by the mammal, administering to the mammal a therapeutically effective amount of a second compound that potentiates the therapeutic effect of gaseous nitric oxide.