Patent ID: 7772426
Filing Date: 2010-08-10
Classification: C07B,C07F

Abstract:
1. A method for producing L-2-amino-4- (hydroxymethylphosphinyl)-butanoic acid represented by formula (5): comprising: subjecting a compound represented by formula (1): wherein R to a hydrogenation reaction under a hydrogen atmosphere in the presence of an asymmetric catalyst to produce a compound represented by formula (4): wherein R subjecting the produced compound represented by formula (4) to hydrolysis; said asymmetric catalyst being represented by formula (2): wherein R or formula (3): wherein L has the same meaning as in formula (2), and Z represents a halogen atom; said formula (6) being: wherein R said formula (8) being wherein R 9 and R 10 represent C 1-4 alkyl groups.