Patent ID: 6274547
Filing Date: 2001-08-14
Classification: A61K,C07K,Y10S

Abstract:
A method of inhibiting binding of IL-11 to the human IL-11 receptor, said method comprising administering a composition comprising a human IL-11R receptor protein, wherein the protein comprises an amino acid sequence selected from the group consisting of:(a) the amino acid sequcnce of SEQ ID NO:2 from amino acid 24 to amino acid 365;(b) the amino acid sequence of SEQ ID NO:2 from amino acid 102 to amino acid 365;(c) the amino acid sequence of SEQ ID NO:2 from amino acid 24 to amino acid 359;(d) the amino acid sequence of SEQ ID NO:2 from amino acid 24 to amino acid 345; and(e) the amino acid sequence of SEQ ID NO:2 from amino acid 24 to amino acid 324.