Patent ID: 7648826
Filing Date: 2010-01-19
Classification: A61P,C12Q,G01N,Y10T

Abstract:
1. A method of detecting a breast cancer marker in a human, said method comprising: (i) providing a biological sample from said human; (ii) detecting the level of CYP24 nucleic acid or CYP24 protein, within said biological sample, wherein said CYP24 nucleic acid or CYP24 protein is a nucleic acid or protein encoded by a vitamin D 24 hydroxylase (CYP24) gene that can be amplified using amplification primers, wherein one primer comprises SEQ ID NO: 1 and another primer comprises SEQ ID NO: 2; and (iii) comparing said level of CYP24 nucleic acid or CYP24 protein with a level of CYP24 nucleic acid or CYP24 protein in a control sample taken from a normal, cancer-free tissue; wherein an increased level of CYP24 nucleic acid or CYP24 protein in said biological sample compared to the level of CYP24 nucleic acid or CYP24 protein in said control sample indicates the presence of said breast cancer marker in said human.