Patent ID: 6326371
Filing Date: 2001-12-04
Classification: A61P,C07D

Abstract:
A method for treating a patient suffering from a mental disorder, which comprises:administering to said patient an effective 5-HT.sub.1A agonistic and 5-HT.sub.2 antagonistic amount of a compound having the formula (I) ##STR15##whereinAr is ##STR16##R.sub.1 and R.sub.2 are each the same or different and are selected from hydrogen or lower alkyl;n is 2 or 3;X is methane;Y is oxygen;A is selected from the following substituted or unsubstituted pyridyl groups ##STR17##whereinR.sub.4 and R.sub.5 are each the same or different and are selected from hydrogen, halogen, lower alkyl, an electron donor group selected from the group consisting of a lower alkoxy group and a hydroxy group, and an electron acceptor group selected from the group consisting of cyano, nitro, trifluoromethyl, COOR.sup.6, CONR.sup.7 R.sup.8 and CO--B, whereinR.sup.6 is hydrogen or lower alkyl,R.sup.7 and R.sup.8 are each the same or different and are selected from hydrogen, lower alkyl or cycloalkyl, andB is ##STR18##m is 1,2,3 or 4, andR.sup.9 is hydrogen or lower alkyl;or a pharmacologically active salt thereof,wherein said mental disorder is at least one selected from the group consisting of a psychoses, depression, and anxiety.