Patent ID: 8945935
Filing Date: 2015-02-03
Classification: B82Y,G01N,Y10T

Abstract:
1. A method of diagnosing, monitoring or prognosing Multiple Sclerosis or stages thereof in a subject, the method comprising the steps of: (a) providing a system comprising an apparatus comprising at least one sensor comprising nanomaterials selected from single walled carbon nanotubes coated with a first organic coating, metal nanoparticles coated with a second organic coating and a combination thereof, wherein the at least one sensor senses at least one volatile biomarker indicative of Multiple Sclerosis or stages thereof through adsorption of the biomarker on the nanomaterials; a detection means; and a processing unit comprising a pattern recognition analyzer comprising at least one pattern recognition algorithm; (b) exposing the at least one sensor to a test exhaled breath sample; (c) measuring at least one response induced parameter from the at least one sensor upon exposure to the test sample to obtain a response pattern; and (d) analyzing the response pattern obtained in step (c) using a pattern recognition algorithm by comparing it to stored data obtained from a control sample whereby a significantly different response pattern of the test sample as compared the control sample is indicative of Multiple Sclerosis or stages thereof.