Patent ID: 6475493
Filing Date: 2002-11-05
Classification: A61K,A61P,Y10S

Abstract:
A coating composition for coating a solid medicament in a pharmaceutical composition, which coating composition is prepared by(i) mixing a mixture comprising: (a) at least 75% by weight of a water insoluble polymer in a latex dispersion, said water insoluble polymer being insoluble in both acidic as well as basic pH; (b) 1 to 25% by weight of an enteric polymer which is substantially insoluble in water at a pH below 4.5 and which is substantially soluble in water at a pH above about 6.0; and (c) a water soluble polymer and (ii) coating said mixture onto the solid medicament and drying thereon, said mixture being heterogeneous, said enteric polymer and said water insoluble polymer and said water soluble polymer being present in an amount effective to control the release of said medicament from the pharmaceutical composition when said pharmaceutical composition coated with said coating composition is placed in an aqueous media, and the sum of the weight percentage of said water insoluble polymer, said water soluble polymer and said enteric polymer in said coating composition being equal to or less than 100%.