Patent ID: 6037362
Filing Date: 2000-03-14
Classification: A61P,C07C,C07D

Abstract:
A compound represented by the general formula (I) or a salt thereof: ##STR27## in which R represents hydrogen atom or methyl, R.sup.1 stands for hydrogen atom, halogen atom, hydroxy, benzyloxy, amino or hydroxymethyl, R.sup.2 stands for hydrogen atom, hydroxymethyl, NHR.sup.3, SO.sub.2 NR.sup.4 R.sup.4' or nitro, wherein R.sup.3 is hydrogen atom, methyl, SO.sub.2 R.sup.5, formyl or CONHR.sup.6', with R.sup.5 being lower alkyl, benzyl or NR.sup.4 R.sup.4' and R.sup.6' being hydrogen atom or lower alkyl, and R.sup.4 and R.sup.4' may be identical with or different from each other and stand each for hydrogen atom, lower alkyl or benzyl, R.sup.6 represents hydrogen atom or lower alkyl, X is secondary nitrogen atom, R.sup.9 stands for hydrogen atom and either one of R.sup.7 and R.sup.8 is hydrogen atom and the other one is hydrogen atom, amino, acetyl amino or hydroxy, and *1 indicates an asymmetric carbon atom and *2 indicates that the carbon atom is asymmetric provided that R.sup.6 is lower alkyl.