Patent ID: 6117985
Filing Date: 2000-09-12
Classification: A61K,C07K,C12N

Abstract:
A negative selection process for enriching and recovering non-hematopoietic tumor cells from a sample containing non-hematopoietic tumor cells and hematopoietic cells, said process comprising(a) reacting the sample with an antibody composition containing antibodies capable of binding to the antigens glycophorin A, CD2, CD14, CD16, CD38, CD45 and CD66b, under conditions so that conjugates are formed between the antibodies and the hematopoietic cells in the sample containing the antigens glycophorin A, CD2, CD14, CD16, CD38, CD45 and CD66b on their surfaces;(b) removing the conjugates; and(c) recovering a cell preparation which is enriched in tumor cells.