Patent ID: 9194871
Filing Date: 2015-11-24
Classification: C07K,G01N,Y10T

Abstract:
1. A method for detecting whether fetal red blood cells or their nucleated precursor cells are present in a sample comprising: (a) contacting a sample with a fluorescently labeled antibody that binds to the surface of fetal red blood cells and their nucleated precursor cells, wherein said antibody is not reactive with CD71 or with surface antigens of adult erythroid, lymphatic, or myeloic cells, under conditions in which the antibody binds to fetal red blood cells and their nucleated precursor cells if present in the sample; and (b) detecting cells bound by said fluorescently labeled antibody if present in the sample, wherein binding of the antibody indicates that the cell is a fetal red blood cell or a nucleated precursor cell thereof.