Patent ID: 7320803
Filing Date: 2008-01-22
Classification: A23K,A61P,C07C,C07D

Abstract:
1. A process for preparing choline ascorbate, wherein the choline ascorbate is obtained in form of anhydrous crystals having diffraction lines at d=3.80 Å and 4.55 Å, and having diffraction lines which are most intense in a range between 3.40 and 4.70 Å, in a 2 Θ X-ray powder diffractogram and having a melting point from 123.5 to 124.4° C. or in the range from 123.5 to 124.4° C., which process comprises a) providing a mixture of ascorbic acid, trimethylamine and a solvent, b) adding to the mixture gaseous ethylene oxide, and c) crystallizing the choline ascorbate, wherein stages (a) and (b) are carried out at a temperature of from 0° C. to 5° C., and the solvent is a water miscible organic solvent or is a mixture of said organic solvent and water.