Patent ID: 8993618
Filing Date: 2015-03-31
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A method for preparing a pharmaceutical composition, the method comprising: (a) extracting a (b) partitioning the first extract with an n-hexane-methanol to obtain an methanol extract; (c) partitioning the methanol extract with a chloroform-water to obtain a chloroform extract; and (d) chromatographing the chloroform extract to obtain the pharmaceutical composition, wherein the pharmaceutical composition comprises at least one of a sesquiterpene coumarin and a diterpene, wherein the sesquiterpene coumarin is 10′R-acetoxy-11′-hydroxyumbelliprenin, and the diterpene is selected from a 5′-hydroxyumbelliprenin, a 10′R-karatavicinol, an 8′-acetoxy-5′S-hydroxyumbelliprenin, a methyl galbanate, a galbanic acid, a farnesiferol C, a farnesiferol A, a conferol, a ligupersin A and an epi-conferdione.