Patent ID: 8993810
Filing Date: 2015-03-31
Classification: C07C

Abstract:
1. A preparation method of lycopene intermediate 3-methyl-4,4-dialkoxy-1-butyraldehyde, comprising the following steps: Step (1): reacting 2-methyl-3,3-dialkoxy-1-halopropane of Formula (2) with magnesium powder in a solvent of anhydrous tetrahydrofuran at a temperature of 45˜65° C. to generate a mixture of Grignard reagent under the protection of an inert gas; and Step (2): adding N,N-disubstituted carboxamide to the mixture of Grignard reagent and reacting at a temperature of 10° C.˜35° C. to obtain 3-methyl-4,4-dialkoxy-1-butaldehyde of Formula (1), its reaction equation is described as follows: wherein R is alkyl.