Patent ID: 7759473
Filing Date: 2010-07-20
Classification: C07H

Abstract:
1. A modified nucleotide n-mer where n=1 with a structure represented by Formula 18 below, comprising a nucleoside unit with a substituent group introduced into the base, wherein said substituent group is bound to said base via a triple bond where Z represents a group comprising a 7-deazaadenine skeleton, 7-deazaguanine skeleton, cytosine skeleton or uracil skeleton independently of the other formulae, and R represents hydrogen or a functional group having 0 to 100 carbon atoms independently of the other formulae, and R 2 represents a hydroxy group, O-β-cyanoethoxy-diisopropylaminophosphine group, O-methoxy-diisopropylaminophosphine group or H-phosphonate group independently of the other formulae, wherein the substituent group is a group selected from the groups represented by Formulae 13-17