Patent ID: 9090627
Filing Date: 2015-07-28
Classification: C07D

Abstract:
1. A compound represented by structural formula (I): or a pharmaceutically acceptable salt or stereoisomer thereof, wherein: R R R X is O, S, or R R each R is independently hydrogen, alkyl, alkenyl, alkynyl, alkoxy, alkylamino, aryl, aryloxy, arylamino, aralkyl, aralkoxy, aralkamino, heteroaryl, heteroaryloxy, heteroarylamino, heteroaralkyl, heteroaralkoxy, heteroaralkamino, cycloalkyl, cycloalkenyl, cycloalkylalkyl, cycloalkoxy, cycloalkamino, heterocyclyl, heterocyclyloxy, heterocyclylamino, heterocyclylalkyl, heterocyclylalkoxy, or heterocyclylalkamino, and is optionally substituted with 1 to 3 A groups; and each A is independently alkyl, alkenyl, alkynyl, alkoxy, alkanoyl, alkylamino, aryl, aryloxy, arylamino, aralkyl, aralkoxy, aralkanoyl, aralkamino, heteroaryl, heteroaryloxy, heteroarylamino, heteroaralkyl, heteroaralkoxy, heteroaralkanoyl, heteroaralkamino, cycloalkyl, cycloalkenyl, cycloalkylalkyl, cycloalkoxy, cycloalkanoyl, cycloalkamino, heterocyclyl, heterocyclyloxy, heterocyclylamino, heterocyclylalkyl, heterocyclylalkoxy, heterocyclylalkanoyl, heterocyclylalkamino, hydroxyl, mercapto, amino, alkanoylamino, aroylamino, aralkanoylamino, alkylcarboxy, alkoxycarbonyloxy, aminocarbonyloxy, alkylaminocarbonyloxy, guanidinyl, ureido, halo, trihalomethyl, cyano, nitro, phosphoryl, sulfonyl, sulfonamido, or azido; wherein each heteroaryl group is independently a 5-6 membered aromatic ring or a 9-12 membered bicyclic ring system wherein at least one ring is an aromatic ring, each aromatic ring having 1-3 heteroatoms selected from O, N, and S; each heterocyclyl group is independently a 3-10 membered saturated or partially unsaturated monocyclic or bicyclic ring having 1-3 heteroatoms selected from O, N, and S; and each cycloalkyl and cycloalkenyl group is independently a 3-10 membered non-aromatic saturated or unsaturated ring in which each atom of the ring is carbon.