Patent ID: 6696090
Filing Date: 2004-02-24
Classification: A61K,A61M

Abstract:
A method for preparing electro-powder constituting micronized medical powder to be electrostatically charged by corona, induction or triboelectric charging and suitable for administration into the deep or upper lung airways by oral inhalation from a dry powder inhaler device, comprising the steps of:selecting an active chemical or biological substance for conversion into an electro-powder; micronizing and electrostatically charging the active substance for determining at least its electrostatic charging capacity and for determining a preparation and manufacturing equipment; preparing a candidate electro-powder preparation in accordance with said electrostatic charging capacity using a selected preparation and manufacturing equipment; analyzing the thereafter prepared candidate electro-powder preparation to verify that the obtained electro-powder has an electrostatic charging capacity rendering it suitable for utilization with a dry powder inhaler; whereby, if the electro-powder is found not to possess said electrostatic charging capacity, the process is repeated with another manufacturing process to prepare a further candidate electro-powder preparation from the active substance.