Patent ID: 7262220
Filing Date: 2007-08-28
Classification: A61P,C07C,C07D

Abstract:
1. A compound of the formula 1, in which W, X, Y are, independently of one another, O or S; R9, R10, R11, R12 are, independently of one another, H, F, Cl, Br, OH, CF R13 is H, (C R1, R2 are, independently of one another, H, (C R3, R4, R5, R6 are, independently of one another, H, F, Cl, Br, OH, CF R14, R15 are, independently of one another, H, (C or the radicals R14 and R15 form with the nitrogen atom to which they are bonded a 3-7-membered, saturated heterocyclic ring which may comprise up to 2 further heteroatoms from the group of N, O or S, where the heterocyclic ring may be substituted up to three times by F, Cl, Br, OH, oxo, N(R16)(R17) or (C R16, R17 are, independently of one another, H, (C heteroalkyl is a 3-7-membered, saturated or up to triunsaturated heterocyclic ring which may comprise up to 4 heteroatoms which correspond to N, O or S, where the heterocyclic ring may be substituted up to three times by F, Cl, Br, CN, oxo, (C R7 is H, (C R8 is N(R18)(R19); R18, R19 are, independently of one another, H, (C or the radicals R18 and R19 form with the nitrogen atom to which they are bonded a 3-7-membered, saturated heterocyclic ring which may comprise up to 2 further heteroatoms from the group of N, O or S, where the heterocyclic ring may be substituted up to three times by F, Cl, Br, OH, oxo, N(R16)(R17) or (C or pharmaceutically acceptable salts thereof, provided the radicals R3, R4, R5, R6, R7, X, Y, and R8 do not have the following meanings at the same time: R3, R4 or R5 is CF R6 is H or CF R7 is H; X is O; and Y is O, S; R8 is substituted or unsubstituted NH-phenyl wherein either the nitrogen atom or the phenyl ring is substituted or unsubstituted.