Patent ID: 8580840
Filing Date: 2013-11-12
Classification: A61P,C07D

Abstract:
1. A method of treating a disorder mediated one or more sex steroid hormone receptors selected from the group consisting of hot flashes, vaginal dryness, osteopenia, osteoporosis, hyperlipidemia, loss of cognitive function, degenerative brain diseases, cardiovascular diseases, cerebrovascular diseases, hormone sensitive cancers, hormone sensitive hyperplasia, endometriosis, uterine fibroids, osteoarthritis, prostate carcinoma, benign prostatic hyperplasia (BPH), hirsitutism, alopecia, anorexia nervosa, breast cancer, acne, AIDS, cachexia, endometriosis, myoma, dysfunctional bleeding, tumors containing steroid receptors, for male contraception, for female contraception, for male performance enhancement, and for hormone replacement in a subject in need of treatment thereof comprising administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising a pharmaceutically acceptable carrier and a compound having the following structure: wherein X is —O—; R  is phenyl; a is 1; R b is 1; R R c is an integer selected from 0 to 1; L R wherein R or a pharmaceutically acceptable salt thereof.