Patent ID: 7071192
Filing Date: 2006-07-04
Classification: A61P,C07D,Y02P

Abstract:
1. A compound of formula an N-oxide, addition salt, quaternary amine, metal complex or stereochemically isomeric form thereof wherein -a wherein each hydrogen atom in the radical (a-1) may optionally be replaced by halo, CH wherein ═Z is ═O, ═CH—C(═O)_NR 5a R 5b , ═CH 2 , ═CH—C 1-6 alkyl, ═N—OH or ═N—O—C 1-6 alkyl; Q is a radical of formula wherein Alk is C Y X X t is 2, 3, 4 or 5; u is 1,2,3, 4 or 5; v is 2 or 3; and whereby each hydrogen atom in Alk and the carbocycles and the heterocycles defined in radicals (b-3), (b-4), (b-5), (b-6), (b-7) and (b-8) may optionally be replaced by R G is a direct bond or C R and said bicyclic heterocycles may optionally be substituted in either of the two cycles with 1 or where possible more substituents selected from halo, hydroxy, amino, cyano, carboxy, C each n independently is 1, 2, 3 or 4; each m independently is 1 or 2; each p independently is 1 or 2; each R R R R R R aryl is phenyl or phenyl substituted with 1 or more substituents selected from halo, hydroxy, CH Het is pyridyl, pyrimidinyl, pyrazinyl, or pyridazinyl.