Patent ID: 8652420
Filing Date: 2014-02-18
Classification: B01L,G01N

Abstract:
1. A chromatographic separation device comprising, directly extending into each other in the fluid flow direction: a) an inlet channel; b) optionally, an open region of 1-20 μm; c) a first flow distribution region that is filled with an array of micro-fabricated pillars, the width of said first flow distribution region being more than doubled with respect to the width of said inlet channel and whereby d) a micro-fabricated separation channel; e) a second flow distribution region that is filled with an array of micro-fabricated pillars, whereby and e) an outlet channel; the width of said second flow distribution region being more than doubled with respect to the width of said outlet channel; wherein said micro-fabricated separation channel comprises a micro-pillar array with micro-pillars substantially smaller in diameter than the micro-fabricated pillars of said first and said second flow distribution region.