Patent ID: 6191273
Filing Date: 2001-02-20
Classification: C07D,C40B

Abstract:
A compound having the formula: ##STR14##wherein:Z is NH, O, or S;n is 0 or 1; andL is a substituent selected from the group consisting of guanidinylarylalkyl, aminoarylalkyl, amidinylpiperazinylcarbonylalkyl, piperazinylcarbonylalkyl, amidinylpiperazinylcarbonylarylalkyl, piperazinylcarbonylarylalkyl, guanidinylalkylaminocarbonylalkyl, aminoalkylaminocarbonylalkyl, guanidinylalkylaminocarbonylarylalkyl, aminoalkylaminocarbonylarylalkyl, benzoimidazolylalkyl, amidinyl, hydroxyamidinyl, hydroxyalkylpyridinylalkyl, arylalkyl, cinnamyl, amidylalkyl, aroyl, alkyloyl, aminoalkyloyl, hydroxaminoyalkyloyl, methoxyaminothioalkyloyl, indolylaminoalkyloyl, amidylaminoalkyloyl, hydroxylcarbonylaminoalkyloyl, guanidinylaminoalkyloyl, imidazolylaminoalkyloyl, amino substituted acyl, carboxyl-substituted arylalkyl and carboxylalkyl-substituted arylalkyl, hydroxysulfonylalkyl, alkyloxycarbonyl substituted pyrimidinyl, alkyloxycarbonyl substituted pyridinyl, carboxyl substituted pyrmidinyl, carboxyl substituted pyridinyl, guanidinylcarbonylalkyl, guanidinylcarbonylarylalkyl, guanidinylcarbonyl substituted pyrimidinyl, guanidinylcarbonyl substituted pyridinyl, alkyloxyphosphatealkyl, pyridinylalkyl, cyanoalkyl, cyanoaryl, nitroalkyl, nitroaryl, alkyloxyalkyl, phenolylalkyl, hydroxylarylalkyl, hydroxyquinolinylalkyl, alkylaminocarbonyl, arylaminocarbonyl, furanylaminocarbonyl, thiofuranylaminocarbonyl, alkylaminothiocarbonyl; arylaminothiocarbonyl, furanylaminothiocarbonyl, thiofuranylaminothiocarbonyl, pyridinylaminothiocarbonyl, 1,2,3-oxadiazolylalkyl, anthraquinone-2-methyl, pyrene-1-butyryl, anthraquinone-2-carbonyl, pyrene-1-carbonyl, 5-(anthraquinone-2-carbonyl)amino-1-pentanyl, 5-(pyrene-1-carbonyl)amino-1-pentanyl, [[[2-(anthraquinone-2-carbonyl)amino]ethylamino]carbonyl]methyl, [[[2-pyrene-1-carbonyl)amino]ethylamino]carbonyl]methyl, and [5-pyrene-1-carbonyl)amino]pentanoxy;or L is a conjugate group.