Patent ID: 7297551
Filing Date: 2007-11-20
Classification: A61K,A61P,C07K,C12N,Y10T

Abstract:
1. A method for purifying a liquid sample by removal of endotoxin, the method comprising immobilizing an isolated polypeptide on an insoluble matrix, contacting said sample with the immobilized polypeptide, and separating said sample from said immobilized polypeptide, wherein the polypeptide comprises a lipopolysaccharide binding domain comprising a peptide selected from the group consisting of: sushi-1Δ peptide (SEQ ID NO:6); sushi-3Δ peptide (SEQ ID NO:8); sushi-4 peptide (SEQ ID NO:9); sushi-5 peptide (SEQ ID NO:10); sushi-6-vg1 peptide (SEQ ID NO:11); sushi-7-vg2 peptide (SEQ ID NO:12); sushi-8-vg3 peptide (SEQ ID NO:13); and sushi-9-vg4 peptide (SEQ ID NO:14), thereby removing endotoxin from the sample.