Patent ID: 6699474
Filing Date: 2004-03-02
Classification: A61K,Y10S

Abstract:
A method for the manufacture of an immunogenic preparation for use as a vaccine,comprising the step of providing at least one substance linked as a hapten to a carrier substance in order to obtain a conjugate, wherein the hapten is a drug of abuse, processing the conjugate by purification and sterile filtration, preparing the purified and filtered conjugate in a number of doses in a physiologically acceptable solution, so that the cumulative dose of the conjugate per vaccination treatment is in excess of 0 micrograms and does not exceed a total amount of 320 micrograms absorbed by a body and induces the lasting protective effect of a vaccine no later than 4 months and over a time span of at least 8 months after the first application of said vaccine, despite repeated drug challenges.