Patent ID: 9168139
Filing Date: 2015-10-27
Classification: A61F,A61L,C12N

Abstract:
1. A method of facilitating augmentation of osseous tissue on a surface of a bone, said method comprising: (a) providing a scaffolding and a rigid enclosure; (b) preparing a surface of a bone for augmentation of osseous tissue, wherein said preparing comprising at least one of: exposing at least one portion of the surface where augmentation is desired; and performing a plurality of minute perforations in at least one cortical portion of said bone where augmentation is desired; (c) placing said scaffolding on the portions of said bone; (d) placing said rigid enclosure onto said scaffolding thereby enclosing said scaffolding relatively to the surface of said bone; (e) seeding cells on said scaffolding thereby obtaining a newly augmented osseous tissue on the surface of said bone wherein said cells are selected from at least one cell culture selected from the group consisting of: an early endothelial progenitor cell culture; an early mesenchymal stem cells culture; a late endothelial progenitor cell culture; a late mesenchymal stem cells culture; peripheral blood derived endothelial progenitor cells and mesenchymal stem cells.