Patent ID: 7098240
Filing Date: 2006-08-29
Classification: A61P,C07D

Abstract:
1. A compound of formula (I) in which: R X represents O or S; R A represents a fused bicyclic ring system wherein one ring is a phenyl ring or a 5- to 7-membered heteroaromatic ring containing one to three heteroatoms selected independently from O, N and S; and the other ring is either a fused phenyl ring or a fused 5- to 7-membered heteroaromatic ring containing one to three heteroatoms selected independently from O, N and S; or a fused 5- to 7-membered saturated ring optionally incorporating one to three heteroatoms selected independently from oxygen, nitrogen and sulphur; said fused bicyclic ring system being optionally substituted by one or more substituents selected independently from halogen, cyano, nitro, —NR n represents an integer 0, 1 or 2; and when n represents 2, each R R W represents O, S(O) Y represents a bond or Y represents a group —(CH R or R or the group CR Z represents: (a) a phenyl ring or a 5- or 6-membered heteroaromatic ring containing one to three heteroatoms selected independently from O, N and S; said phenyl or heteroaromatic ring being optionally substituted by one or more substituents selected independently from halogen, cyano, —NR (b) a saturated 3- to 7-membered ring optionally incorporating one or two heteroatoms selected independently from O, N and S, and optionally incorporating a carbonyl group; said saturated ring being optionally substituted by one or more substituents selected independently from halogen, cyano, —NR (c) Z represents hydroxyl, C R R R R R R m, r, s, u and v independently represent an integer 0, 1 or 2; and pharmaceutically acceptable salts thereof.