Patent ID: 7105546
Filing Date: 2006-09-12
Classification: A61P,C07D

Abstract:
1. A compound having formula (I): or a pharmaceutically acceptable salt thereof, wherein: X is selected from —CH A and B are independently (C R E is a saturated, partially saturated or unsaturated, or aromatic monocyclic ring containing 5 carbon atoms and 1 nitrogen atom; wherein 1 to 4 hydrogen atoms in E are optionally and independently replaced with halogen, hydroxyl, hydroxymethyl, nitro, SO each of R each n is independently 0 to 4; each Z is independently selected from a saturated, partially saturated or unsaturated, monocyclic or bicyclic ring system, wherein each ring contains 5 to 7 ring atoms independently selected from C, N, N(R wherein 1 to 4 hydrogen atoms in Z are optionally and independently replaced with halo, hydroxy, nitro, cyano, C(O)OH, (C J and K, taken together with the nitrogen and carbon atom to which they are respectively bound, form a 5-membered heterocyclic ring, wherein 1 to 4 hydrogen atoms in said heterocyclic ring are optionally and independently replaced with (C K G, when present, is —S(O) Y is oxygen, or N(R wherein R D is phenyl, wherein 1 to 4 hydrogen atoms in D are optionally and independently replaced with halogen, hydroxyl, hydroxymethyl, nitro, SO x is 0 or 1.