Patent ID: 6780997
Filing Date: 2004-08-24
Classification: A61P,C07D,C07F

Abstract:
A compound of the formula IV in whichR1 is hydrogen or alkyl; R2 is â€”CHO, â€”CH2OH, â€”CH3 or â€”CO2R5 in which R5 is hydrogen, alkyl, or aryl; or R2 is â€”CH2O-alkyl- in which alkyl is covalently bonded to the oxygen at the 3-position instead of R1; R3 and R3â€² are independently hydrogen or halo; or R3 and R3â€² taken together constitute a second covalent bond between the carbons to which they are substituent; and R4 is hydrogen; or a pharmaceutically acceptable acid addition salt thereof.