Patent ID: 9089417
Filing Date: 2015-07-28
Classification: A61F,A61L,A61P,C12N

Abstract:
1. A method to decrease transplant time and/or need for donor skin as a source of dermal or epidermal cells, the method comprising providing to a patient a device comprising cultured autologous or allogeneic dermal cells, or porcine dermal cells directly attached to a biocompatible reticulated acellular matrix, the matrix prepared from a matrix-forming collagen-containing fluid that is cast, frozen, and dehydrated, the dermal cells providing a cellular lamination layer with cultured autologous or allogeneic epidermal cells or xenogeneic porcine epidermal cells directly inoculated and directly attached thereon which establishes a basement membrane between the epidermal cells and the dermal cells, the dermal and/or epidermal cells supplemented at least in part with allogeneic dermal or epidermal cells or porcine cells, the device available for transplant and/or requiring reduced donor skin due to the allogeneic dermal or epidermal cells or porcine cells.