Patent ID: 6322965
Filing Date: 2001-11-27
Classification: A61K,C07K,C12N,Y10S

Abstract:
A hepatitis C virus (HCV) chimeric antigen peptide that specifically binds to antibodies produced by an HCV-infected human consisting of:a) the peptide region of the HCV NS3 region shown as position 1-74 or 1-76 of SEQ ID NO:39, the peptide region of the HCV NS3 region shown as position 1-98 of SEQ ID NO:40, the peptide region of the HCV NS4 region show as position 1-39 of SEQ ID NO:41, the peptide region of the HCV Core region shown as position 1-15 of SEQ ID NO:37, and the peptide region of the HCV NS4 region shown as position 9-27 of SEQ ID NO:42 of the HCV polypeptide belonging to the genotype group 1;b) the peptide region of the HCV NS4 region shown as position 1-36 of SEQ ID NO:43, the peptide region of the HCV Core region shown as position 1-15 of SEQ ID NO:38, and the peptide region of the HCV NS4 region shown as position 1-24 of SEQ ID NO:44 of the HCV polypeptile belonging to the genotype group 2; andc) the peptide region of the HCV Core region shown as position 1 to position 43 or from position 1 to position 42 of SEQ ID NO: 36, the HCV polypeptide belonging to the genotype group 1 or 2, wherein the above regions may be joined by a linker peptide having no epitope activity.