Patent ID: 6689766
Filing Date: 2004-02-10
Classification: A61P,C07C,C07F,Y02P

Abstract:
A vitamin D3 compound expressed by the following general formula (1) or pharmaceutically permissible solvates thereof, wherein, R01 and R02 are each independently a hydrogen atom, a trimethylsilyl group, a triethylsilyl group, a t-butyldimethylsilyl group, an acetyl group, a methoxymethyl group or a tetrahydro-4H-pyran-2-yl group; Z is represented by formula (1-5), â€ƒin the above formula (1-5), R51 expresses â€”CONR511R512, â€”COR513 or â€”C(OH) R514R515, wherein R511 and R512 are identical to or different from each other, and they are a hydrogen atom or a C1-C4 alkyl group, or both the members together express a nitrogen-containing C3-C8 alkyl ring or a morpholino group in cooperation with the nitrogen atom to which they are bonded; and R513, R514 and R515 are identical to or different from each other, and they express a C1--C4 alkyl group; R52 expresses a methyl group, an ethyl group, a trifluoromethyl group or a pentafluoroethyl group.