Patent ID: 9222938
Filing Date: 2015-12-29
Classification: C07K,G01N

Abstract:
1. A biosensor for use in detecting the presence of ovarian cancer, said biosensor comprising an immunoassay for detecting a presence of a serum antibody reactive with at least one marker antigen indicative of ovarian cancer, said at least one marker antigen being incorporated into said immunoassay, said at least one marker antigen being selected from the group consisting of polypeptides comprising SEQ ID NOS: 153, 154, 155, 156, 157, 158, 161, 162, 163, 164, 165, 166, 167, 168, 171, 172, 173, 174, 176, 177, 178, 179, 180, 183, 184, and 186, each of said polypeptides being either an isolated polypeptide or an insert in frame with the T7 10B gene product in an isolated T7 phage display antigen clone; polypeptides consisting of SEQ ID NOS: 160, 175, and 181, each of said polypeptides being either an isolated polypeptide or an insert in frame with the T7 10B gene product in an isolated T7 phage display antigen clone; and polypeptides consisting of SEQ ID NOS: 159, 169, 170, 182, and 185, each of said polypeptides being an insert in frame with the T7 10B gene product in an isolated T7 phage display antigen clone.