Patent ID: 6114351
Filing Date: 2000-09-05
Classification: A61P,C07D

Abstract:
Antibacterial compositions based on N-oxides of saturated nitrogen-containing heterocycles which are substituted by quinolone- or naphthyridonecarboxylic acids of the formula (I): ##STR13## in which X represents hydrogen, halogen, C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy, NH.sub.2,Y represents radicals of the structures: ##STR14## in which: R.sup.4 represents straight-chain or branched C.sub.1 -C.sub.4 -alkyl which is optionally substituted by hydroxyl or methoxy, cyclopropyl, acyl having 1 to 3 C atoms,R.sup.5 represents hydrogen, methyl, phenyl, thienyl or pyridyl,R.sup.6 represents hydrogen or C.sub.1-4 -alkyl,R.sup.7 represents hydrogen or C.sub.1-4 -alkyl,R.sup.8 represents hydrogen or C.sub.1-4 -alkyl, andR.sup.1 represents an alkyl radical having 1 to 3 carbon atoms, cyclopropyl, 2-flouroethyl, methoxy, 4-flourophenyl, 2,4-diflourophenyl or methylamino,R.sup.2 represents hydrogen or alkyl having 1 to 6 carbon atoms, which is optionally substituted by methoxy or 2-methoxyethoxy, and cyclohexyl, benzyl, 2-oxopropyl, phenacyl, ethoxycarbonylmethyl, pivaloyloxymethyl,A represents nitrogen or .dbd.CH--, .dbd.C(halogen)--, .dbd.C(OCH.sub.3)--, .dbd.C(CH.sub.3)--,and their pharmaceutically utilizable hydrates, acid addition salts and salts with bases, excluding: ##STR15##