Patent ID: 6365190
Filing Date: 2002-04-02
Classification: A61K,B01D,B01J,Y10S

Abstract:
A method for preparing a dry powder composition, said method comprising:preparing an aqueous solution of a hydrophilic component; preparing an organic solution of a hydrophobic component in an organic solvent; delivering the aqueous solution containing the hydrophilic component to an atomizer; delivering the organic solution containing the hydrophobic component to the atomizer separately from the aqueous solution containing the hydrophilic component; atomizing the two solutions together in the atomizer to produce droplets containing both components; and flowing the droplets of the aqueous solution and the organic solution in a heated gas stream to form dry particles comprising a mixture of the hydrophilic and hydrophobic components, said particles having a size distribution wherein at least 85% of the particles by weight comprise particles having an average size in the range from 0.4-5 &mgr;m.