Patent ID: 6288212
Filing Date: 2001-09-11
Classification: A61K,A61P,C07K,Y02A

Abstract:
An isolated antimicrobial peptide having an amino acid sequence selected from the group consisting of:KWKSFIKKLTSAAKKVVTTAKPLALIS (SEQ ID NO: 3);KWKSFIKKLTKAAKKVVTTAKKPLIV (SEQ ID NO: 4);KWKKFIKSLTKSAAKTVVKTAKKPLIV (SEQ ID NO: 5);KWKLFKKIGIGAVLKVLKVLTTGLPALKLTLK (SEQ ID NO: 6);KLFKKIGIGAVLKVLKVLTTGLPALKLTLK (SEQ ID NO: 7);KWKFKKIGIGAVLKVLKVLTTGLPALKLTLK (SEQ ID NO: 8);KLWKLFKKIGIGAVLKVLKVLTTGLPALKLTLK (SEQ ID NO: 9);KWKSFIKKLTSAAKKVTTAAKPLTK (SEQ ID NO: 10);KWKKFIKKIGIGAVLKVLTTGLPALKLTKK (SEQ ID NO: 11);KKWKKFIKKIGIGAVLTTPGAKK (SEQ ID NO: 12);GWGSFFKKAAHVGKHVGKAALTHYL-NH2 (SEQ ID NO: 14);KGWGSFFKKAAHVGKHVGKAALTHYL (SEQ ID NO: 15);KGWGSFFKKAAHVGKHVGKAALTHYL-NH2 (SEQ ID NO: 16);ALWKTMLKKAAHVKHVGKAALTHYL-NH2 (SEQ ID NO: 17);SIGSAFKKAAHVGKHVGKAALTHYL-NH2 (SEQ ID NO: 18);GWGSFFKKAAHVGKHVGKAALGAAARRRK (SEQ ID NO: 19);ALWKTMLKKAAHVGKHVGKAALGAAARRRK (SEQ ID NO: 20); andSIGSAFKKAAHVGKHVGKAALGAAARRRK (SEQ ID NO: 21);and analogs, derivatives, amidated variations and conservative variations thereof.