Patent ID: 9078921
Filing Date: 2015-07-14
Classification: A61K,A61P

Abstract:
1. A pharmaceutical dosage form which comprises a melt-processed mixture of at least one active ingredient that is present as a solid dispersion, at least one pharmaceutically acceptable homopolymer or copolymer of N-vinylpyrrolidone and a solubilizing composition, the solubilizing composition comprising (i) at least one tocopheryi compound having a polyalkylene glycol moiety and (ii) at least one alkylene glycol fatty acid monoester or mixture of alkylene glycol fatty acid mono- and diester, wherein said dosage form comprises, relative o the weight of the melt-processed mixture, from about 0.5 to 40% by weight of said active ingredient, 40 to 99% by weight of said pharmaceutically acceptable homopolymer or copolymer of N-vinylpyrrolidone, 0.5 to 20% by weight of said solubilizing composition, and 0 to 15% by weight of additives.