Patent ID: 6465241
Filing Date: 2002-10-15
Classification: C07B,C07H,C12Q,C40B,G01N

Abstract:
A nucleic acid accumulation analyzing chip comprising:i. an first optical waveguide having a radiation input port and a radiation output port; ii. at least one optical microcavity having a bottom face, said at least one optical microcavity placed in said first optical waveguide along its optical path; and iii. at least one oligonucleotide being immobilized to said bottom face of said optical microcavity, such that when said at least one oligonucleotide is contacted with reaction reagents under conditions allowing a nucleic acid accumulation reaction to take place, accumulated nucleic acid is detectable by providing radiation at said radiation input port of said optical waveguide and monitoring radiation signal modulation at said radiation output port of said first optical waveguide.