Patent ID: 6417167
Filing Date: 2002-07-09
Classification: A61K

Abstract:
A lyophilized composition comprising the &agr;-glycosylceramide represented by the following formula (A) or a salt thereof; a polyoxysorbitan fatty acid ester; histidine; and a disaccharide or monosaccharide: whereinR1 represents H or OH, X denotes an integer in the range of 7-25, R2 represents any one of the substituents defined in the following (a)-(e): (a) â€”CH2(CH2)YCH3, (b) â€”CH(OH)(CH2)YCH3, (c) â€”CH(OH)(CH2)YCH(CH3)2, (d) â€”CH&boxH;CH(CH2)YCH3, (e) â€”CH(OH)(CH2)YCH(CH3)CH2CH3, wherein Y denotes an integer n the range of 5-17, either one of R3 or R4 represents H, and the other represents H, OH, NH2 or NHCOCH3, either one of R5 or R6 represents H, and the other represents OH, either one of R7 or R8 represents H, and the other represents OH, R9 represents H, CH3 or CH2OH.