Patent ID: 6596868
Filing Date: 2003-07-22
Classification: C07D

Abstract:
A process for synthesizing an anhydroecgonine compound which comprises reacting a cycloheptatriene compound represented by the formula (1): wherein n is an integer of 0 or 1; and R1 is a cyano group in the case of n being 0, and R1 is selected from an alkyl group and a C7-10 aralkyl group in the case of n being 1, with a primary amine represented by the formula (2):R2NH2â€ƒâ€ƒ(2) wherein R2 is a hydrogen atom, an unsubstituted alkyl group, a substituted alkyl group, an unsubstituted C7-10 aralkyl group or a substituted C7-10 aralkyl group, or a slat thereof a ammonia in the presence of a base to obtain an anhydroecgonine compound represented by the formula (3): wherein R1 and R2 are as defined above.