Patent ID: 9221029
Filing Date: 2015-12-29
Classification: A61K,A61P,B01J,C07B

Abstract:
1. An automatic system for synthesizing iodine-123 meta-iodobenzylguanidine ( 123 I-MIBG), comprising: a first reactor, for subjecting radioactive iodine-containing sodium iodide and meta-iodobenzylguanidine (MIBG) sulfate, which are fed into the first reactor through a line and under the control of a solenoid valve, to an iodine-iodine exchange reaction to obtain radioactive labeled MIBG; a purification unit, for performing elution purification on the radioactive iodine labeled MIBG, which is fed into the first reactor through the line by using the solenoid valve, by means of column chromatography with water and ethanol, to collect a fraction eluted with the ethanol; and a second reactor, for distilling an ethanol eluent purified by the purification unit to remove the ethanol, and then placing a phosphate buffer is fed to obtain a phosphate buffered solution containing