Patent ID: 7396561
Filing Date: 2008-07-08
Classification: B01J,C07B,C07H,C12Q,C40B,G01N,Y10T

Abstract:
1. Process for the formation of a polyfunctional polymer network covalently attached to a sensor surface, wherein said network comprises cross linked polymer subchains having a multitude of identical or different repeating units carrying one or more functional groups which allow an interaction of the polymer with sample or probe molecules, the process comprising the steps of: (a) covering the sensor surface with a monolayer of a polymerization initiator which comprises one or more functional groups suitable for covalent attachment to the surface; (b) contacting the polymerization initiator monolayer with a solution comprising polymerization initiators, cross-linkers, and a polymerizable mixture of monomers and comonomers carrying functional groups which allow an interaction with sample or probe molecules; wherein said contacting is followed by simultaneously initiating and carrying out a crosslinking polymerization reaction both in solution and on the sensor surface.