Patent ID: 6656517
Filing Date: 2003-12-02
Classification: A61L,A61M

Abstract:
A method of coating an intracorporeal medical device, comprising:a) applying to the medical device a solution having a grafting component and a binding component, wherein the grafting component is selected from the group consisting of vinyl, acrylate and allyl compounds, and the binding component has at least a first functional group selected from the group consisting of aziridine, carbodiimide, aldehyde, isocyanate, succinimide, maleimide, oxirane, and carboxyl derivatized with one of carbodiimide, tresyl, or succinimide; b) polymerizing the grafting component in the presence of the binding component, so that the grafting component polymerizes on the medical device, and bonding the grafting component to the binding component, to form a base coat on the device; and c) applying to the base coat a top coat having a functional group which binds to the binding component.