Patent ID: 6171869
Filing Date: 2001-01-09
Classification: B01D,C07K,G01N,Y02A,Y10T

Abstract:
A process for desalting and concentrating a protein-containing solution, wherein the protein-containing solution contains unwanted ions that need to be removed from the solution so that the protein-containing solution is desalted, said process comprising:(a) modifying an ultrafiltration device to contain an ion exchange resin for absorbing the unwanted ions contained in the protein-containing solution; (b) adding a protein-containing solution to said ultrafiltration device;(c) subjecting said ultrafiltration device to centrifugation to separate the ion exchange resin with absorbed ions from the protein-containing solution and to form a desalted and a concentrated solution; and (d) recovering the concentrated and desalted solution from said ultrafiltration device.