Patent ID: 6034095
Filing Date: 2000-03-07
Classification: C07C,C07D

Abstract:
A compound of the formula: ##STR20## wherein: Q is arylheteroalkyl wherein the aryl portion is phenyl or naphthyl, and can be unfused or fused with the heteroalkyl ring;the heteroalkyl ring having six atoms, one or two of the atoms being nitrogen;Y has the formula: ##STR21## wherein: R.sup.1 and R.sup.2 are independently H, alkyl having from one to about 14 carbons, cycloalkyl having from 3 to about 10 carbons, or a natural or unnatural side chain of an L-amino acid, said alkyl and cycloalkyl groups being optionally substituted with one or more J groups;J is halogen, lower alkyl, aryl, heteroaryl, amino optionally substituted with one to three aryl or lower alkyl groups, guanidino, alkoxycarbonyl, aralkoxycarbonyl, alkoxy, hydroxy, or carboxy; andG is hydrogen; C(.dbd.O)NR.sup.3 R.sup.4 ; CH.sub.2 R.sup.5 or C(.dbd.O)OR.sup.3 ;wherein:R.sup.3 and R.sup.4 are each independently hydrogen, alkyl having from 1 to about 10 carbons, said alkyl groups being optionally substituted with one or more J groups, aryl having from about 6 to about 14 carbons, and aralkyl having from about 7 to about 15 carbons; andR.sup.5 is halogen;with the proviso that if G is hydrogen and Q is alkyl substituted with J, and said J is an .alpha.-amino group, then the .alpha.-amino nitrogen must be tertiary;further provided that Q is not xanthene-9-yl.