Patent ID: 6534511
Filing Date: 2003-03-18
Classification: A61K,A61P

Abstract:
A method of treating male erectile dysfunction, comprising administering, to a male human in need of said treatment an effective amount of a compound of formula (II): whereinR1 is C1-C6 alkyl; R2 is H; methyl or ethyl; R3 is C2-C4 alkyl; R4 is H; C1-C4 alkyl optionally substituted with NR5R6, CN, CONR5R6 or CO2R7; C2-C4 alkenyl optionally substituted with CN, CONR5R6 or CO2R7; C2-C4 alkanoyl optionally substituted with NR5R6; SO2NR5R6; CONR5R6; CO2R7 or halo; R5 and R6 are each independently H or C1-C4 alkyl; or, together with the nitrogen atom to which they are attached, form a pyrrolidino, piperidino, morpholino, 4-(NR8)-1-piperazinyl or 1-imidazolyl group wherein said group is optionally substituted with one or two C1-C4 alkyl groups; R7 is H or C1-C4 alkyl; and R8 is H; C1-C3 alkyl or (hydroxy)C2-C3 alkyl; or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition containing either entity.