Patent ID: 6984719
Filing Date: 2006-01-10
Classification: A61K,C07K

Abstract:
1. A prostaglandin F2 receptor antagonist consisting of an amino acid sequence derived from the second extracellular loop of a prostaglandin F2 receptor, said amino acid sequence consisting of one or more sequences selected from the group consisting of ilghrdyk (PCP-8; SEQ ID NO:1); ILGHRDYK (PCP-13; SEQ ID NO:13); ILAHRDYK (PCP-13.7, SEQ ID NO:4); ILGFRDYK (PCP-13.11; SEQ ID NO:5); ILGHKDYK (PCP-13.13; SEQ ID NO:6); ILGHRNYK (PCP-13.14; SEQ ID NO:7); ILGHQDYK (PCP-13.18; SEQ ID NO:8); ILGHRDY-amide (PCP-13.20; SEQ ID NO:9); ILGHRDYK-amide (PCP-13.21; SEQ ID NO:15); ILGWRDYK (PCP-13.22; SEQ ID NO:10); ILaHRDYK (PCP-13.8; SEQ ID NO:14); and ILGXRDYK (PCP-13.24; SEQ ID NO:11), wherein X is cyclohexyl alanine, and wherein small letters indicate L-amino acids and capital letters indicate D-amino acids.