Patent ID: 9125805
Filing Date: 2015-09-08
Classification: A61K,A61P

Abstract:
1. A method for treating or preventing anxiety, muscle spasms, or seizures, the method comprising parenterally administering to a subject in need thereof a stable liquid formulation comprising: (a) a biocompatible solvent consisting of dimethylsulfoxide (DMSO) or a mixture of DMSO and n-methyl pyrrolidone (NMP); and (b) a small molecule drug, or a salt thereof, solubilized within the solvent, wherein the small molecule drug is diazepam, and wherein diazepam is present in the liquid formulation in an amount up to its solubility limit in the formulation, wherein the liquid formulation comprises less than 5% by weight residual water, and wherein a volume of the liquid formulation to be parenterally injected is 3 ml or less.