Patent ID: 6673905
Filing Date: 2004-01-06
Classification: A61K,C07K,C08B,C12N,Y02A

Abstract:
A method of coupling a first biomolecule to a second biomolecule, comprising:(a) covalently attaching a diene moiety to the first biomolecule to form a diene component; (b) covalently attaching a dienophile to the second biomolecule to form a dienophile component; and (c) contacting the diene component with the dienophile component under conditions that permit a cycloaddition reaction to occur between the components, wherein one of said first and second biomolecules is a polysaccharide hapten or antigen, and the other of said first and second biomolecules is a peptide, protein, or polysaccharide carrier.