Patent ID: 7160886
Filing Date: 2007-01-09
Classification: A61P,C07D

Abstract:
1. A compound of structural formula I: or a pharmaceutically acceptable salt thereof; wherein X is selected from the group consisting of  wherein heteroaryl is selected from pyridinyl, furyl, thienyl, pyrrolyl, oxazolyl, thiazolyl, triazolyl, triazinyl, tetrazolyl, thiadiazolyl, imidazolyl, pyrazolyl, isoxazolyl, isothiazolyl, oxathiazolyl, pyrimidinyl, pyrazinyl, pyridazinyl, quinolyl, and isoquinolyl, and wherein phenyl, naphthyl, and heteroaryl are unsubstituted or substituted with one to three groups independently selected from R R  wherein phenyl, naphthyl, and heteroaryl are unsubstituted or substituted with one to three groups independently selected from R R  wherein phenyl and naphthyl are unsubstituted or substituted with one to three groups independently selected from R each R  wherein alkenyl, phenyl, naphthyl, heteroaryl are unsubstituted or substituted with one to three substituents independently selected from halogen, hydroxy, C each R R  wherein phenyl, naphthyl, and heteroaryl are unsubstituted or substituted with one to three groups independently selected from R R R  wherein any methylene (CH each R  wherein alkyl, alkenyl, cycloalkyl, heterocycloalkyl, and bicycloalkyl are unsubstituted or substituted with one to three groups independently selected from R each R  wherein alkyl, phenyl, heteroaryl, heterocycloalkyl, and cycloalkyl are unsubstituted or substituted with one to three groups independently selected from halogen, C r is 1 or 2; s is 1; m is 0; n is 0, 1, 2, 3, or 4; and p is 0, 1, or 2.