Patent ID: 6376212
Filing Date: 2002-04-23
Classification: C12N

Abstract:
A selection marker comprising an isolated nucleotide sequence which codes for a polypeptide with eutypine reductase activity, said polypeptide comprising the following amino acid sequence SEQ ID NO:2:Met Ser Thr Ala Ala Gly Lys Leu Val Cys Val Thr Gly Ala Ser Gly Tyr Ile Ala Ser Trp Leu Val Lys Phe Leu Leu Glu Arg Gly Tyr Thr Val Lys Ala Thr Val Arg Asp Thr Asn Asp Pro Lys Lys Val Asp His Leu Leu Ser Leu Asp Gly Ala Lys Glu Arg Leu His Leu Val Lys Ala Asn Leu Leu Glu Glu Gly Ser Phe Asp Ser Ala Val Glu Gly Val His Ala Val Phe His Thr Ala Ser Pro Phe Phe Asn Asp Ala Lys Asp Pro Gln Thr Glu Leu Leu Asp Pro Ala Val Lys Gly Thr Leu Asn Val Leu Lys Ser Cys Val Asn Ser Pro Thr Leu Lys Arg Val Val Leu Thr Ser Ser Ile Ala Ala Val Ala Phe Ser Asp Arg Pro Lys Asn Pro Asp Val Val Val Asp Glu Thr Trp Tyr Ser Asp Pro Glu Tyr Cys Lys Arg Thr Gly Leu Trp Tyr Asn Leu Ser Lys Thr Leu Ala Glu Asp Ala Ala Try Lys Phe Ala Lys Glu Asn Asn Ile Asp Leu Val Thr Met Asn Pro Ala Leu Val Val Gly Pro Leu Leu Gln Pro Val Leu Asn Thr Ser Ala Ala Ile Val Leu Gly Leu Val Asn Gly Ala Lys Thr Phe Lys Asn Ala Ser Leu Gly Trp Val Asp Val Lys Asp Val Ala Leu Ala His Ile Leu Ala Tyr Glu Asn Ala Ser Ala Asn Gly Arg Tyr Leu Leu Val Glu Arg Val Ala His Phe Gly Asp Ala Ala Lys Ile Leu Arg Asp Leu Tyr Pro Thr Leu Gln Ile Pro Asp Lys Cys Glu Asp Asp Lys Pro Leu Glu Pro Ile Phe Gln Val Ser Lys Glu Lys Ala Lys Ser Leu Gly Ile Asp Tyr Ile Pro Leu Glu Val Ser Leu Lys Asp Thr Val Glu Ser Leu Lys Glu Lys Lys Phe Leu Lys Val.