Patent ID: 6350744
Filing Date: 2002-02-26
Classification: A61P,C07D

Abstract:
A compound of the formula whereinA is hydrogen, or a saturated heterocyclic group, linked via a carbon atom, selected from pyrrolidine, morpholine and piperidine; with the nitrogen atom or other ring atoms of said saturated heterocyclic group optionally substituted with hydrogen or C1-C6 alkyl; Q[, U, V and W are independently] is CH or N; U and V arc each CH; W is N; R1 is hydrogen or NH(C1-C6 alkyl) aryl; R2, R3 and R4 independently represent a member selected from the group consisting of hydrogen, halo, hydroxy, CF3, NH2, NO2, C1-C6 alkyl, 1-3 substiuent substituted C1-C6 alkyl, C1-C6 alkoxy, 1-3 substiuent substituted C1-C6 alkoxy, C3-C8 cycloalkyl, 1-3 substiuent substituted C3-C8 cycloalkyl, or aryl, wherein said substitents are each independently C3-C6cycloalkyl; or a pharmaceutically acceptable addition salt and/or hydrate thereof, or where applicable, a geometric or optical isomer or racemic mixture thereof.