Patent ID: 8936762
Filing Date: 2015-01-20
Classification: G01N,Y10T

Abstract:
1. A line-scan imaging device for rapid image analysis of particles or biological cells in at least one sample of interest, comprising: a. a microfluidic device comprising a plurality of microchannels, wherein each microchannel has an inlet and at least one outlet; b. a scanning-imaging detector configured to produce one dimensional (1-D) or low complexity two dimensional (2-D) line images of sufficient resolution for running the image through a cell-type algorithm and also configured to record emitted fluorescence from a particle or biological cell within each of the plurality of microchannels of the microfluidic device; and c. an output device configured to receive data input from the scanning-imaging detector, wherein the data input from the 1-D or 2-D line images run through the cell-type algorithm produces 1-D or sparse 2-D images of sufficient resolution to identify cell features, and wherein the output device comprises a storage device and/or a data analysis system that permits cell phenotype determination from the emitted fluorescence detected in step (b).