Patent ID: 7335356
Filing Date: 2008-02-26
Classification: A61K,C07K

Abstract:
1. A purified monoclonal antibody which binds Ebola virus GP, which comprises two heavy chains and two light chains, each chain comprising a variable region and a constant region, wherein the heavy chain variable regions each have an amino acid sequence that includes complementarity-determining regions having the amino sequences of SEQ ID NO:13 located at position 31-35, SEQ ID NO:14 located at position 50-65, and SEQ ID NO:15 located at position 95-102, which complementarity-determining region positions are determined according to the Kabat numbering system, and wherein the light chain variable regions each have an amino acid sequence that includes complementarity-determining regions having the amino sequences of SEQ ID NO:18 located at position 24-34, SEQ ID NO:19 located at position 50-56, and SEQ ID NO:20 located at position 89-97, which complementarity-determining region positions are determined according to the Kabat numbering system.