Patent ID: 7709240
Filing Date: 2010-05-04
Classification: C12N,C12P

Abstract:
1. An isolated AMP deaminase having the amino acid sequence of SEQ ID NO: 1 comprising the following characteristics: (1) action catalyzing a reaction of acting on 5′-nucleotide including adenosine as a component so as to deaminate the 5′-nucleotide; (2) substrate specificity acting on 5′-AMP, 5′-dAMP, ADP, ATP, and 3′, 5′-cyclic AMP, which are 5′-nucleotides including adenosine as a component, and acting on 5′-AMP most favorably; (3) optimum temperature having an optimum temperature of around 65° C.; (4) temperature stability being stable at a temperature of 65° C. or less; (5) optimum pH having an optimum pH of around 5.6; (6) pH stability being stable at pH 6.0 to pH 8.5; and (7) molecular weight having a molecular weight of 48,000±2,000 in gel filtration and 60,000±3,000 in SDS-PAGE.