Patent ID: 8692051
Filing Date: 2014-04-08
Classification: A01K,A61K,G01N

Abstract:
1. A method of testing a Caloric Restriction (CR) mimetic or a CR mimetic candidate, the method comprising: selecting at least one of the CR mimetic or the CR mimetic candidate; administering the selected at least one of the CR mimetic or the CR mimetic candidate to a subject; determining antioxidant capabilities of the at least one of the CR mimetic or the CR mimetic candidate, wherein the determining includes determining: (i) a half maximal inhibitory concentration (IC determining in the subject, a level of a biological parameter of a known CR marker by comparing the level of the known CR marker to measurements of a corresponding CR marker from a subject having been administered at least one of the CR mimetic or the CR mimetic candidate, the biological parameter of the known CR marker includes an RNA transcript level of a gene known to be effected in gene expression by a CR diet or a known CR mimetic.