Patent ID: 6051257
Filing Date: 2000-04-18
Classification: A61K,Y10S

Abstract:
A method for making a powder batch comprising a plurality of pharmaceutically-active particles, comprising the steps of:(a) providing a solution comprising pharmaceutically-active particle precursors;(b) forming said solution into a plurality of droplets;(c) suspending said droplets in a carrier gas selected from the group consisting of nitrogen, argon and helium;(d) classifying said droplets to remove substantially all droplets having a size greater than a predetermined size; and(e) heating said droplets at a temperature sufficient to remove liquids from said droplets and produce a substantially dry pharmaceutical powder batch wherein said pharmaceutically active particles are selected from the group consisting of MePhe peptides, glutathione, RGD peptides, dDAVP, renin, cyclosporine, leuprolide acetate, insulin, interferon-.alpha., calcitonin, growth hormone, antitrypsin and albumin.