Patent ID: 7704753
Filing Date: 2010-04-27
Classification: G01N,Y10S,Y10T

Abstract:
1. A device for detecting the presence or absence of an analyte in a sample comprising: a matrix which defines a flow path for a liquid sample, the matrix having a groove therein; a sample application zone on the matrix for receiving the liquid sample; a reagent zone on the matrix downstream of the sample application zone and in fluid communication with the sample application zone, the reagent zone comprising a specific binding agent, the specific binding agent comprising a label and a molecule specific for an analyte; a detection zone on the matrix downstream of the reagent zone and in fluid communication with the sample application zone and the reagent zone, the detection zone comprising an analyte binding area and a positive control pad, the positive control pad comprising at least one positive control filament that fits within the groove in the matrix, the positive control filament comprising one or more components that exhibit a first color when dry and a second color when wet; and wherein in the absence of the analyte, wetting of the positive control pad and the positive control filament causes a first recognizable symbol to form on the matrix, and wherein in the presence of the analyte, wetting of the positive control pad, the positive control filament and binding of analyte at the analyte binding area causes a second recognizable symbol to form on the matrix, the second recognizable symbol being different from the first recognizable symbol.