Patent ID: 6184205
Filing Date: 2001-02-06
Classification: A61K,A61P,C07K,C40B,G01N

Abstract:
A purified peptide that binds to the N terminal SH3 domain of Grb2, said peptide consisting of an amino acid sequence selected from the group consisting of:KWDSLLPALPPAFTVE (SEQ ID NO: 224),RWDQVLPELPTSKGQI (SEQ ID NO: 225);RFDFPLPTHPNLQKAH (SEQ ID NO: 226);RLDSPLPALPPTVMQN (SEQ ID NO: 227);RWGAPLPPLPEYSWST (SEQ ID NO: 228);YWDMPLPRLPGEEPSL (SEQ ID NO: 229);RFDYNLPDVPLSLGTA (SEQ ID NO: 230);TKKPNAPLPPLPAYMG (SEQ ID NO:231);KWDLDLPPEPMSLGNY (SEQ ID NO: 232);YYQRPLPPLPLSHFES (SEQ ID NO: 234);YYRKPLPNLPRGQTDD (SEQ ID NO: 235);YFDKPLPESPGALMSL (SEQ ID NO: 236);YFSRALPGLPERQEAH (SEQ ID NO: 237);SLWDPLPPIPQSKTSV (SEQ ID NO: 239);SYYDPLPKLPDPGDLG (SEQ ID NO: 240);KLYYPLPPVPFKDTKH (SEQ ID NO: 241); andDPYDALPETPSMKASQ (SEQ ID NO: 242).