Patent ID: 6900054
Filing Date: 2005-05-31
Classification: A61K,A61P,C12N,G01N

Abstract:
1. A method of obtaining glial cells comprising: (a) isolating glial restricted precursor cells from central nervous system tissue by negative immunoselection of E-NCAM positive calls followed by positive immunoselection with an A2B5 antibody, said glial restricted precursor cells being immunonegative for PDGF-α receptor, PDGF-β receptor, and Ran-2 antigen, not labeled with R24 anti-GD3 antibody, and immnunopositive for A2B5 antigen; and (b) plating said isolated glial restricted precursor cells of step (a) under differentiating conditions, thereby causing said isolated glial restricted precursor cells to differentiate into glial cells.