Patent ID: 7041853
Filing Date: 2006-05-09
Classification: C07C

Abstract:
1. A process for producing 4-bromothioanisole which comprises the steps of: reacting thioanisole with bromine to produce a mixture of 4-bromothioanisole and byproduct 2-bromothioanisole; adding an alcoholic solvent to the mixture of 4-bromothioanisole and 2-bromothioanisole, wherein the alcoholic solvent is methanol or a mixed solvent composed of not less than 30% by weight of methanol and not more than 70% by weight of water; cooling the mixture to a temperature of −20 to 30° C. to selectively crystallize 4-bromothioanisole; and isolating crystals of 4-bromothioanisole to separate 4-bromothioanisole from 2-bromothioanisole.