Patent ID: 8008460
Filing Date: 2011-08-30
Classification: A61K,A61P,C07K,C12N,G01N

Abstract:
1. An isolated polynucleotide molecule comprising a nucleotide sequence of an infectious human endogenous retrovirus, which sequence is or is complementary to a sequence which: (a) has at least 99% identity to the full length of SEQ ID NO:1; (b) has 100% identity to a fragment of SEQ ID NO:1, the fragment comprising at least 15 contiguous nucleotides of SEQ ID NO:1 and including at least one of nucleotides 416, 602, 630, 639, 654, 738, 799, 802, 866, 945, 953, 972, 1149, 1348, 1413, 1642, 1653, 1668, 1701, 1989, 2068, 2087, 2090, 2097, 2100, 2124, 2163, 2198, 2238, 2253, 2273, 2305, 2313, 2330, 2461, 2808, 2815, 2816, 2878, 2938, 2974, 3052, 3091, 3105, 3124, 3178, 3363, 5402, 5719, 6456, 6458, 6464, 6802, 7146, 7262, 7340, 7347, 7388, or 7436 of SEQ ID NO:1; and/or (c) comprises the sequence inserted into a vector pCR4-Topo and deposited as any of “MERV-env”, “MERV-gag”, “MERV-prt” and “MERV-pol” at the DSMZ on 26 Sep. 2001.