Patent ID: 6264960
Filing Date: 2001-07-24
Classification: A61K,Y10S

Abstract:
A method for treating a human having a lipid profile of a HDL-C level of less than about 40 mg/dL prior to treatment, and a LDL-C level of less than about 130 mg/dL prior to treatment, wherein the human is at risk for a cardiovascular or cerebrovascular event, comprising administering to the human an effective amount of a fibric acid of derivative thereof in a pharmaceutically acceptable carrier, wherein the fibric acid or derivative thereof is selected from a group consisting of: gemfibrozil, fenofibrate, bezafibrate, ciprofibrate, clofibrate and clinofibrate; the cardiovascular or cerebrovascular event is selected from a group consisting of: thrombotic disorder, myocardial infarction, angina, stroke, transient ischemic attack, thrombotic re-occlusion subsequent to a coronary intervention procedure and a disorder in which at least one major coronary artery exhibits greater than 50% stenosis; and wherein an increase of HDL-C occurs after treatment.