Patent ID: 8501780
Filing Date: 2013-08-06
Classification: A61P,C07D

Abstract:
1. A compound according to Formula (I): wherein: Z is optionally substituted thienyl wherein the thienyl is optionally substituted with one or more substituent independently selected from the group consisting of: halo, optionally substituted C R1 is —WX; W is a bond; and X is optionally substituted piperidinyl optionally substituted with one or more substituent independently selected from the group consisting of: halo, optionally substituted C each Ra is independently selected from the group consisting of: H, optionally substituted C each Rb is independently selected from the group consisting of: H and optionally substituted C each Rc is independently selected from the group consisting of: H, optionally substituted C each Rd is independently optionally substituted C each Re is independently selected from the group consisting of: optionally substituted C each Rf is independently selected from the group consisting of: H and optionally substituted C each Rg is independently selected from the group consisting of: optionally substituted C each Rh is independently selected from the group consisting of: H, C Rx and Ry taken together with the nitrogen atom to which they are attached form a ring having from 5 to 7 member atoms wherein said ring optionally contains one additional heteroatom as a member atom, said ring is saturated or unsaturated but not aromatic, and said ring is optionally substituted with one or two C or a pharmaceutically-acceptable salt thereof.