Patent ID: 6531503
Filing Date: 2003-03-11
Classification: A61P,C07D,Y02P

Abstract:
A benzofuran derivative of formula I whereinR is 1-piperazinyl, 4-R1-piperazinyl or L, Râ€² is 2-R2-5-R3-pyrrol-1-ylcarbonyl, 4-R4-piperazin-1-ylcarbonyl, N,N-di(tert-butyloxycarbonyl)aminocarbonyl, â€”CH&boxH;C(R5R6), benzofuran-2-yl-Câ‰¡Câ€”, â€”C(Hal)3, â€”COâ€”C(Hal)3, 1,4-dihydrobenzo[d][1,2]oxazin-3-ylcarbonyl or 3,4-dihydrobenzo-1H-phthalazin-2-ylcarbonyl, L is Cl, Br, I or an OH or a reactive functionally modified OH group, R1, R4 in each case independently of one another are H, benzyl or another amino protective group, R2, R3 in each independently of one another are H or alkyl having 1-6 C atoms, R5, R6 in each case independently of one another are alkyl having 1-6 C atoms, and Hal is F, Cl, Br or I, or a salt thereof.