Patent ID: 9132394
Filing Date: 2015-09-15
Classification: B01F,B01L,G01N

Abstract:
1. A detection system for droplet-based assays, comprising: a channel network defining a flow path for droplets extending through a confluence region configured to increase an average distance between droplets, and to an examination region disposed downstream of the confluence region; and a detector operatively connected to the examination region, wherein the channel network includes a droplet inlet channel configured to carry droplets to the confluence region, wherein the droplet inlet channel forms a tapered region and a neck region extending from the tapered region to the confluence region, wherein the tapered region is sized such that droplets enter the neck region in single file, wherein the flow path has a smaller diameter in the neck region than in the examination region, and wherein at least one dilution inlet channel meets the droplet inlet channel at the confluence region and is configured to provide a dilution fluid that increases the average distance between droplets.