Patent ID: 8288162
Filing Date: 2012-10-16
Classification: B01J,B82Y,G01N,Y10T

Abstract:
1. A nano-particle biochip substrate, comprising: a substrate having attached directly thereto, such that each is secured in one position on or in a surface of the substrate and at least some protrude above the surface of the substrate, substantially spherical nano-particles having an average cross sectional diameter of from about 0.1 nm to 50 nm, wherein the nano-particles are distributed in a spatially-controlled manner across the surface and are each useful to directly immobilize only one moiety of interest, and wherein the moiety of interest is selected from the group consisting of a protein or a peptide, an antibody or an antibody fragment, an amino acid, a lipid, a sugar, a salt, a cell lysate, a protein fragment, or a cell.