Patent ID: 6395754
Filing Date: 2002-05-28
Classification: A61K,A61P,C07D,Y02A

Abstract:
A 2,6-dioxopiperidine selected from the group consisting of (a) a compound of the formula: in which:one of X and Y is C&boxH;O and the other of X and Y is C&boxH;O or CH2; R6 is hydrogen, alkyl of 1 to 8 carbon atoms, benzyl, chloro, or fluoro; R7 is m-phenylene, p-phenylene or â€”(CnH2n)â€” in which n has a value of 0 to 4; each of R8 and R9 taken independently of the other is hydrogen or alkyl of 1 to 8 carbon atoms, or R8 and R9 taken together are tetramethylene, pentamethylene, hexamethylene, or â€”CH2CH2X1CH2CH2â€” in which X1 is â€”Oâ€”, â€”Sâ€” or â€”NHâ€”; and, R10 is hydrogen, alkyl of 1 to 8 carbon atoms, or phenyl; and, (b) the acid addition salts of said compounds which contain a nitrogen atom capable of being protonated.