Patent ID: 6090618
Filing Date: 2000-07-18
Classification: A01K,A61K,A61P,C07K,C12N

Abstract:
A viral vector competent to infect a mammalian host cell, said vector comprising an SM22.alpha. promoter operably linked to a nucleotide sequence encoding a polypeptide or RNA other than mouse SM22.alpha., said promoter having a maximum of 441 base pairs and comprising(a) nucleotides 900-1340 of SEQ ID NO:1, or(b) a sequence hybridizing with the complement of nucleotides 899-1382 of SEQ ID NO:1 under hybridizing conditions comprising 0.02M-0.15M sodium chloride at temperatures of 50.degree. C. to 70.degree. C., such that said nucleotide sequence encoding said polypeptide or RNA is expressed when said vector is provided to a smooth muscle cell.