Patent ID: 6370478
Filing Date: 2002-04-09
Classification: G16B,G16H

Abstract:
A method for predicting the likelihood of an interaction between two different perturbations, comprising:calculating a correlation coefficient between a first and a second response profile, wherein said first response profile comprises measurements of a plurality of cellular constituents in a first sample of a cell, tissue, organ or multicellular organism in response to a first perturbation, and said second response profile comprises measurements of said plurality of cellular constituents in a second sample of said cell, tissue, organ or multicellular organism in response to a second perturbation different from said first perturbation; and predicting the likelihood of an interaction between said first perturbation and said second perturbation based on said correlation coefficient; wherein said interaction is the alteration of the effects of said second perturbation by said first perturbation or the alteration of the effects of said first perturbation by said second perturbation, and wherein a high possibility of interaction is predicted if said correlation coefficient is high.