Patent ID: 7250402
Filing Date: 2007-07-31
Classification: A61K,A61P,C07H

Abstract:
1. A compound represented by the general formula (I) or a salt thereof: wherein, represents —CH═CH—, —CH 2 C(═O)—, —CH 2 —CH 2 —, or —CH 2 —CH(R 13 )— (wherein R 13 represents a hydroxyl group or a lower alkylcarbonyloxy group, between R 1 and the carbon atom at 4′-position represents a single bond or a double bond, between R 2 and the carbon atom at 5-position represents a single bond or a double bond, and 1) when represents —CH═CH— or —CH 2 —CH 2 —, and between R 1 and the carbon atom at 4′-position represents a double bond, R when between R 2 and the carbon atom at 5-position represents a single bond, R 2 represents a hydroxyl group, a lower alkoxyl group, or a lower alkenyloxycarbonyloxy group, and when between R 2 and the carbon atom at 5-position represents a double bond, R 2 is combined together with the carbon atom at 5-position to form a carbonyl group or a hydroxime group (—C(═NOH)—); 2) when represents —CH═CH— or —CH 2 —CH 2 —, and between R 1 and the carbon atom at 4′-position represents a single bond, R when between R 2 and the carbon atom at 5-position represents a single bond, R 2 represents a hydroxyl group, a lower alkoxyl group, or a lower alkenyloxycarbonyloxy group, and when between R 2 and the carbon atom at 5-position represents a double bond, R 2 is combined together with the carbon atom at 5-position to form a carbonyl group or a hydroxime group (—C(═NOH)—); 3) when represents —CH 2 —C(═O)—, and between R 1 and the carbon atom at 4′-position represents a double bond, R between R 2 and the carbon atom at 5-position represents a single bond, and R 2 represents a hydroxyl group, a lower alkoxyl group, or a lower alkenyloxycarbonyloxy group; 4) when represents —CH 2 —C(═O)—, and between R 1 and the carbon atom at 4′-position represents a single bond, R when between R 2 and the carbon atom at 5-position represents a single bond, R 2 represents a hydroxyl group, a lower alkoxyl group, or a lower alkenyloxycarbonyloxy group, and when between R 2 and the carbon atom at 5-position represents a double bond, R 2 is combined together with the carbon atom at 5-position to form a carbonyl group or a hydroxime group (—C(═NOH)—); 5) when represents —CH 2 —CH(R 13 )— (wherein R 13 has the same meaning as that defined above), and between R 1 and the carbon atom at 4′-position represents a double bond, R between R 2 and the carbon atom at 5-position represents a single bond, and R 2 represents a hydroxyl group, a lower alkoxyl group, or a lower alkenyloxycarbonyloxy group; and 6) when represents —CH 2 —CH(R 13 )— (wherein R 13 has the same meaning as that defined above), and between R 1 and the carbon atom at 4′-position represents a single bond, R when between R 2 and the carbon atom at 5-position represents a single bond, R 2 represents a hydroxyl group, a lower alkoxyl group, or a lower alkenyloxycarbonyloxy group, and when between R 2 and the carbon atom at 5-position represents a double bond, R 2 is combined together with the carbon atom at 5-position to form a carbonyl group or a hydroxinre group (—C(═NOH)—).