Patent ID: 6028207
Filing Date: 2000-02-22
Classification: A61P,C07J

Abstract:
A compound represented by the following formula (I):X--Y--Z (I)wherein X is a monovalent group represented by the following formula (II): ##STR51## wherein R.sub.1 is hydrogen or a hydroxyl group, R.sub.2 is hydrogen or a hydroxyl group, R.sub.3 is hydrogen or a methyl group and R.sub.4 is hydrogen, halogen or a dimethylamino group;Y is a divalent group represented by the following formula (IV) or (V): ##STR52## wherein n is 0 to 4, and --X'-- is a direct bond, --O-- or --NH--; and Z is a monovalent group formed by removing a hydrogen atom or a hydroxyl group from a compound represented by the following formula (VI): ##STR53## wherein R.sub.1 ' is HO-- or O.dbd.; R.sub.2 ' is a hydrogen atom or a methyl group; R.sub.3 ' is a hydrogen atom, a phenyl group or a substituted phenyl group; R.sub.4 ' is a methyl group or an ethyl group; R.sub.5 ' is a hydroxyl group, a ketone group or an acetyl group; R.sub.6 ' is hydrogen, a hydroxyl group, a methyl group, an ethynyl group or a propynyl group; or R.sub.5 ' and R.sub.6 ' together form .dbd.O; R.sub.7 ' is hydrogen, a hydroxyl group or .dbd.O, or R.sub.6 ' and R.sub.7 ' are together bonded to oxygen atoms of a 2,2-dioxypropyl group; and the symbol . . . represents a single bond or a double bond; whereby this bond group exists at the 2-position, 3-position, 4-position, 6-position, 7-position or 17-position, or at the phenyl group bonded to the 11-position, (1) of the formula (II) and (2) of the formulas (IV) and (V) are directly bonded, and (3) of the formulas (IV) and (V) and any of the bond groups of the formula (VI) are directly bonded.