Patent ID: 6187774
Filing Date: 2001-02-13
Classification: C07D

Abstract:
A compound of the formula (I) ##STR253##whereinR is a group having the following formula (3), ##STR254##whereinY is a linear or branched C.sub.1 -C.sub.4 alkylene optionally having a substituent R.sup.1a at an optional position, wherein R.sup.1a is alkyl, hydroxy, alkoxy, amino or alkylamino,A is void, or an oxygen atom, a sulfur atom, SO, SO.sub.2 or N--R.sup.7 wherein R.sup.7 is hydrogen, alkyl, arylalkyl or acyl,B is a linear or branched C.sub.1 -C.sub.4 alkylene optionally having a substituent R.sup.1b at an optional position, wherein R.sup.1b is alkyl, hydroxy, alkoxy, amino or alkylamino, andR.sup.3 is a hydrogen, an alkyl, an acyl or an aryl;D is void, or a linear or branched alkylene having 1 to 8 carbon atoms;Q--T is CH.sub.2 --N;G is void, or a linear or branched alkylene having 1 to 8 carbon atoms or a carbonyl;R.sup.5 is a hydrogen or an alkyl; andR.sup.6 is an optionally substituted aryl, an optionally substituted heteroaryl or an optionally substituted fused heteroaryl, the optional substituent being selected from the group consisting of halogen, haloalkyl, alkyl, alkoxy, hydroxy, nitro, amino, methylamino and dimethylamino,an optical isomer thereof or a pharmaceutically acceptable salt thereof.