Patent ID: 8515686
Filing Date: 2013-08-20
Classification: G01N,H01J

Abstract:
1. A method for testing whether a target polypeptide is present in a sample of a set of polypeptides comprising: a) providing a sample of a set of polypeptides to be tested for the presence of a target polypeptide; b) selecting a database corresponding to the set of polypeptides having information stored therein that describes a characteristic of each polypeptide of the set, wherein the database is created according to the following steps comprising: c) interrogating the database to determine a value for the target polypeptide that can be used to configure a mass spectrometer to exclude the detection of polypeptides having a value that is not the same as the value determined for the target polypeptide, so that the target polypeptide may be selectively detected by the mass spectrometer; d) utilizing the value determined for the target polypeptide to configure the mass spectrometer; e) applying the sample of the set of polypeptides to the configured mass spectrometer; and f) utilizing the configured mass spectrometer to test whether the target polypeptide is present in the sample of the set of polypeptides.