Patent ID: 7603151
Filing Date: 2009-10-13
Classification: A61B

Abstract:
1. A non-invasive method of determining the concentration of an analyte using Raman spectral information, the method comprising the acts of: applying a high-intensity, narrow band of light to a first side of tissue, the high-intensity light entering the tissue and generating a Raman signal; placing a Raman-generating material in a location nearest a second side of the tissue, the second side being located generally opposite of the first side; reflecting the high-intensity light from the Raman-generating material so as to produce an additional Raman signal that passes through the tissue towards the first side of the tissue; reflecting the Raman signal generated from the high-intensity light entering the tissue towards the first side of the tissue via the Raman-generating material; collecting the Raman signal generated from the high-intensity light entering the tissue and the additional Raman signal generated from the Raman-generating material; and determining the analyte concentration using information from the collected Raman signals.