Patent ID: 8193394
Filing Date: 2012-06-05
Classification: A61P,C07C,C07D

Abstract:
1. A method for producing a compound expressed by the formula (5), comprising the following sequential steps of: (a) reacting compounds expressed by the formulae (1), (2) and (3) below in the presence of an acid catalyst to prepare one of a compound expressed by the formula (4) or a mixture of stereoisomers thereof; where, in the formula above, R where, in the formula above, R′ represents at least one substituent selected from a hydrogen atom, an alkyl group, an acyl group, an alicyclic group, an aromatic group, a halogen atom, a hydroxyl group, an alkyloxy group, an acyloxy group, and a cyano group; M represents a silicon atom, a boron atom, a tin atom, a zinc atom, or a magnesium atom; R where, in the formula above, R where, in the formula above, R (b) preparing one of a compound expressed by the formula (5) below and a mixture of stereoisomers thereof by halogen-induced carbocyclization reaction of one of a compound expressed by the formula (4) and a mixture of stereoisomers thereof; where, in the formula above, R