Patent ID: 6623724
Filing Date: 2003-09-23
Classification: A61K,A61Q

Abstract:
A composition for treating a skin proliferative disorder or a disorder of keratinization, which comprises:a) an effective amount of one or more of: (i) a saturated C7 to C50 diol having the following structure: whereineach R is independently selected from R1; R2; hydroxyl, methyl, hydroxymethyl, â€”(CH2)nCH3â€”, â€”(CH2)nOH, â€”(CH2)nOR1, â€”(CH2)nâ€”CH(OH)â€”CHOH, â€”(CH2)nâ€”CH(OH)â€”CH(OH)R1, â€”(CH2)nâ€”CH(OH)â€”(CH2)nâ€”CH2(OH), â€”(CH2)nâ€”CH(OH)â€”(CH2)nâ€”CH(OH)R1 or â€”CH2OR1, wherein each n is independently an integer from 0-25; each R1is independently selected from hydrogen; halogen; an acyl or amino acyl group containing from one atom to twenty atoms, at least one of which is carbon, nitrogen, oxygen, or sulfur; or a group containing from one atom to twenty atoms, one of which is carbon, nitrogen, oxygen, or sulfur, and R2 is a linear, branched or unbranched, cyclic, bicyclic or polycyclic group containing from one atom to fifty atoms, at least one of which is carbon, nitrogen, oxygen, or sulfur; or (ii) an unsaturated C7 to C50 diol having the above structure; or (iii) a pharmaceutically acceptable salt or prodrug of (i); or (iv) a pharmaceutically acceptable salt or prodrug of (ii); and b) a suitable carrier.