Patent ID: 7691263
Filing Date: 2010-04-06
Classification: B01D,B01J,G01N

Abstract:
1. A monolith for liquid chromatography comprising a continuous mesoporous skeletal structure with nanometer-sized pores in the skeletal structure, the skeletal structure essentially non-adsorptive to proteins with a functional group selected to impart a desired interaction property to the monolith, the skeletal structure providing structural integrity to the monolith, the skeletal structure comprising reaction product of; crosslinker having at least three adjacent groups, selected from ethylene oxide, polyethylene oxide, and mixtures thereof, and two or more pendent vinyl groups, monomer having the formula, where R is H or CH 3 , where Z is the functional group selected to impart a desired interaction property to the monolith, and where Y is nothing, or any group that will not materially affect or compete with the function of the functional group (Z) in the monolith, or the reactivity of vinyl groups in the crosslinker or monomer.