Patent ID: 6455703
Filing Date: 2002-09-24
Classification: A61K,C07D

Abstract:
A compound of the formula: wherein R1 and R2 are independently selected from the group consisting of hydrogen, lower alkyl, and benzyl; R3 is selected from the group consisting of substituted or unsubstituted pyrazolyl, and pyrazolidinyl, wherein said substituents are one to three independently selected from the group consisting of halogen, lower alkyl, lower alkoxy, amino, lower alkylamino, di-lower alkylamino, hydroxy, nitro, nitrile, carboxyl, aminosulfonyl, lower alkyl mercapto, and lower alkylsulfonyl; R4 is selected from the group consisting of substituted or unsubstituted pyrazolyl, and pyrazolidinyl, wherein said substituents are one to three independently selected from the group consisting of halogen, lower alkyl, lower alkoxy, amino, lower alkylamino, di-lower alkylamino, hydroxy, nitro, nitrile, carboxyl, aminosulfonyl, lower alkyl mercapto, and lower alkylsulfonyl; R5 is selected from the group consisting of hydrogen, lower alkyl, halogen, hydroxy, amino, lower alkyl amino, and dilower alkylamino; Y is selected from the group consisting of CH2, C&boxH;O, CHâ€”OH m is an integer from 0-3 X is selected from the group consisting of CH2, C&boxH;O, CHâ€”OH, and SO2; and n is an integer from 0-2.