Patent ID: 9144543
Filing Date: 2015-09-29
Classification: A61K,A61P

Abstract:
1. A biodegradable intraocular implant consisting of: a) a first poly(D,L lactide-co-glycolide) polymer having a molecular weight of about 11,200 daltons and an intrinsic viscosity of about 0.2 dL/g; b) a second poly(D,L lactide-co-glycolide) polymer having a molecular weight of about 11,700 daltons and an intrinsic viscosity of about 0.2 dL/g; and c) brimonidine free base in an amount of about 40% by weight of the implant, based on the total weight of the implant; wherein the ratio of the first poly(D,L lactide-co-glycolide) polymer to the second poly(D,L lactide-co-glycolide) polymer in the implant is 1:1 or 3:1; and wherein the implant is i) a solid, rod-shaped implant formed by an extrusion process, and wherein the first poly(D,L lactide-co-glycolide) polymer and the second poly(D,L lactide-co-glycolide) polymer are together in the implant in an amount of about 60% by weight of the implant, based on the total weight of the implant.