Patent ID: 6514688
Filing Date: 2003-02-04
Classification: B03C,C07K,C08F,C08J,C08K,C08L,G01N,H01F,Y10S

Abstract:
A method for detecting or quantifying one or more specific biological materials in a mixture of substances, comprising:coupling one or more types of ligands to the outer surface of spherical magnetic polymer particles, comprising cross-linked polyvinyl alcohol, said particles ranging in size from 1 to 10 &mgr;m; incubating the magnetic polymer particles having one or more types of ligands coupled to the outer surface in a mixture of substances, said mixture containing one or more biological materials; binding one or more of the biological materials from said mixture of substances to the one or more types of ligands coupled to the surface of the magnetic polymer particles; isolating the magnetic polymer particles having one or more biological materials bound to the outer surface from the mixture of substances; and detecting or quantifying the one or more biological materials bound to the outer surface of the magnetic polymer particles, by applying an analytical method selected from the group consisting of immunoassays, photometry, DNA sequencing or polymerage chain reaction.