Patent ID: 7645607
Filing Date: 2010-01-12
Classification: C12P

Abstract:
1. A method for producing (S)—N-protected-propargylglycine of formula (2), wherein the method comprises asymmetrically hydrolyzing an N-protected-propargyiglycine ester of formula (1) by an asymmetric hydrolysis enzyme or a cultured substance of a microorganism having an ability of producing said enzyme, wherein, R 1 represents an alkyl group having 1 to 4 carbon atoms, R 2 and R 3 each independently represent a hydrogen atom or a protective group of an amino group, R 2 and R 3 being not simultaneously a hydrogen atom, and a carbon atom appended with a mark * represents an asymmetric carbon atom, wherein the asymmetric hydrolysis enzyme is a lipase, protease, acylase, esterase, or α-amylase obtained from a microorganism selected from the group consisting of