Patent ID: 8192732
Filing Date: 2012-06-05
Classification: A61K,A61P,C12N

Abstract:
1. A method for improving cognitive function in a human patient, the method comprising the step of: (a) administering a pharmaceutically effective amount of more developmentally potent cells to the patient; wherein the more developmentally potent cells are obtained by contacting neural stem cells or mesenchymal stem cells with an effective amount of substituted deoxynucleotide or deoxynucleoside for an effective period, wherein the substituted deoxynucleotide or deoxynucleoside compound-contacted neural stem cells or mesenchymal stem cells become more developmentally potent, and wherein said more developmentally potent cells are capable of migrating to an area of neurological deficit, differentiating in a tissue-specific manner and functioning in a manner that improves cognitive function.