Patent ID: 6280729
Filing Date: 2001-08-28
Classification: A61K,A61P,C07K,C12N,C12Y

Abstract:
A method of treating Christmas disease in a patient which comprises administering to such patient an effective amount of a therapeutic composition comprising an aqueous solution of purified factor IX having a specific activity of greater than about 50 units factor IX activity/mg protein, wherein the composition is capable of being stored for a period of time of about 2 weeks at a storage temperature up to 15-30.degree. C. and wherein at the end of said period of storage the composition has a factor IX specific activity of greater than about 50 units and is free of factor IX.sub.a, degraded forms of factor IX and/or active forms of other clotting factors in concentrations which would tend to cause detectable adverse clinical effects in a human when said composition is administered in a therapeutic dose.