Patent ID: 9161949
Filing Date: 2015-10-20
Classification: A61K,A61P

Abstract:
1. A method for attenuating free radical formation resulting from a bodily insult wherein the bodily insult comprises a reaction caused by a drug selected from a group consisting of antibiotics, nonsteroidal anti-inflammatory drugs, and chemical agents for cancer treatment, said method comprising administering bicarbonate into the body of a subject in need thereof at a dosage ranging from 1.5 mEq/kg of body weight to 5.0 mEq/kg of body weight within a 24-hour period, and wherein a pre-insult dosage of 25%-40% of the bicarbonate is administered prior to the bodily insult, and a remaining 60%-75% of the bicarbonate is administered after the pre-insult dosage within the 24-hour period.