Patent ID: 7652143
Filing Date: 2010-01-26
Classification: A61P,C07D

Abstract:
1. A compound of the formula I: and/or all stereoisomeric forms of the compound of the formula I and/or mixtures of these forms in any ratio, and/or a physiologically tolerated salt of the compound of the formula I, wherein, Z is —C(O)—, R1 and R2 are identical or different and are independently of one another hydrogen atom or —(C R3 and R4 are identical or different and are independently of one another: a covalent bond, —(CH m is the integer 1, and in which the alkylene radical which is formed by —(CH V V hydrogen atom, —(C6-C14)-aryl in which aryl is phenyl and is unsubstituted or substituted once or twice by R8 or the radical -G-M, or a mono- or bicyclic 4- to 15-membered heterocycle in which heterocycle is a radical from the series benzodioxol, quinolinyl or pyridyl, in which the heterocycle is unsubstituted or substituted once, twice or three times by R8 or the radical -G-M, M is: 2-[3-(6-benzyloxypyridin-3-ylmethyl)-2-oxoimidazolidin-1-yl]-N-hydroxy-3-methylbutyramide, 2-(3-biphenyl-4-ylmethyl-2-oxoimidazolidin-1-yl)-N-hydroxy-3-methylbutyramide, 2-[3-benzyl-5-(4-methoxyphenyl)-2-oxoimidazolidin-1-yl]-N-hydroxy-3-methylbutyramide, N-hydroxy-2-[3-(4-hydroxybenzyl)-2-oxoimidazolidin-1-yl]-3-methylbutyramide, N-hydroxy-2-[3-(3-hydroxybenzyl)-2-oxoimidazolidin-1-yl]-3-methylbutyramide, N-hydroxy-3-methyl-2-{2-oxo-3-[4-(pyridin-4-ylmethoxy)benzyl]imidazolidin-1-yl}butyramide with trifluoroacetic acid (TFA), N-hydroxy-3-methyl-2-{2-oxo-3-[4-(pyridin-3-ylmethoxy)benzyl]imidazolidin-1-yl}butyramide with TFA, N-hydroxy-3-methyl-2-{2-oxo-3-[4-(pyridin-2-ylmethoxy)benzyl]imidazolidin-1-yl}butyramide with TFA, 2-[3-(4-but-2-ynyloxybenzyl)-2-oxoimidazolidin-1-yl]-N-hydroxy-3-methylbutyramide, N-hydroxy-3-methyl-2-{3-[4-(2-methylquinolin-4-ylmethoxy)benzyl]-2-oxoimidazolidin-1-yl}butyramide with TFA, 2-[3-benzyl-5-(4-methoxybenzyl)-2-oxoimidazolidin-1-yl]-N-hydroxy-3-methylbutyramide, 2-[3-(4-benzyloxybenzyl)-5-(4-methoxybenzyl)-2-oxoimidazolidin-1-yl]-N-hydroxy-3-methylbutyramide, N-hydroxy-2-[5-(4-methoxybenzyl)-3-methyl-2-oxoimidazolidin-1-yl]-3-methylbutyramide, 2-[5-benzo[1,3]dioxol-5-ylmethyl-3-(4-benzyloxybenzyl)-2-oxoimidazolidin-1-yl]-N-hydroxy-3-methylbutyramide, 2-(5-benzo[1,3]dioxol-5-ylmethyl-3-benzyl-2-oxoimidazolidin-1-yl)-N-hydroxy-3-methylbutyramide or 2-[3-(4-benzyloxyphenyl)-2-oxo-[1,3]diazepan-1-yl]-N-hydroxy-3-methyl-butyramide.