Patent ID: 9066854
Filing Date: 2015-06-30
Classification: A61K,A61P,Y10S

Abstract:
1. A method of treating premature ejaculation in a patient complaining of premature ejaculation comprising: administering meatally to a patient in need of treatment of premature ejaculation an ejaculation latency prolonging amount of a semi-solid composition comprising: 0.5 percent-4.0 percent by weight based on the weight of the composition of dyclonine as a topical anesthetic; about 0.1 mg to about 0.5 mg of a vasoactive prostaglandin selected from the group consisting of prostaglandin E a polymeric thickener selected from the group consisting of a shear-thinning polysaccharide gum and a shear-thinning polyacrylic acid polymer; a lipophilic component that is selected from the group consisting of an aliphatic C about 0.25 to about 5 percent by weight based on the weight of the composition a penetration enhancer that is dodecyl 2-(N,N-dimethylamino)-propionate or a pharmaceutically acceptable salt; water; and a buffer system that provides a buffered pH value for said composition in the range of about 3 to about 7.4; wherein administering the semi-solid composition confers prolongation of baseline ejaculation latency time to the patient, thereby treating premature ejaculation in the patient.