Patent ID: 6689861
Filing Date: 2004-02-10
Classification: C08G

Abstract:
A method of making a geminal bisphosphonate-derivatized polyurethane, the method comprising (i) grafting a 1,&ohgr;-dibromoalkyl compound with a urethane amino moiety of a polyurethane to form a &ohgr;-bromoalkyl-substituted polyurethane and (ii) grafting a geminal bisphosphonate thiol with the &ohgr;-bromoalkyl-substituted polyurethane to form the geminal bisphosphonate-derivatized polyurethane, wherein said 1,&ohgr;-dibromoalkyl compound is selected from the group consisting of C2-C18 1,&ohgr;-dibromoalkyl compounds.