Patent ID: 7683095
Filing Date: 2010-03-23
Classification: A61K

Abstract:
1. A method of lowering serum cholesterol, Apo B or LDL cholesterol comprising orally administering to a mammal having elevated levels of serum cholesterol, Apo B or LDL cholesterol an oral pharmaceutical dosage form selected from the group consisting of a tablet or a capsule, said dosage form comprising at least one pharmaceutically acceptable excipient and a combination of (a) at least one limocitrin derivative selected from the group consisting of limocitrin-3,7,4′-trimethylether; limocitrin-3,5,7,4′-tetramethylether; and limocitrin-3,7,4′-trimethylether-5-acetate, and (b) at least one quercetin derivative selected from the group consisting of quercetin tetramethylether; quercetin 3,5-dimethylether-7,3′,4′-tribenzylether; quercetin pentamethylether; quercetin-5,7,3′,4′-tetramethylether-3-acetate; and quercetin-5,7,3′,4′-tetramethylether; to provide about 1-1000 mg/day limocitrin derivative and about 1-1000 mg/day quercetin derivative.