Patent ID: 9018253
Filing Date: 2015-04-28
Classification: A61K,A61P,C07C

Abstract:
1. A compound is selected from the group consisting of: 1-(2-chlorophenyl)-1 -hydroxyproply -2-carbamate, 1-(2-chlorophenyl)-1-hydroxy-3-methyl-butyl-2-carbamate, 1-(2-chlorophenyl)-1-hydroxyhexyl-2-carbamate, 1-(2-chlorophenyl)-1-hydroxypropyl-2-N-methylcarbamate, 1-(2-chlorophenyl)-1-hydroxypropyl-2-N-propylcarbamate, 1-(2-chlorophenyl)-1-hydroxypropyl-2-N-isopropylcarbamate, 1-(2-chlorophenyl)-1-hydroxypropyl-2-N-cyclopropylcarbamate, 1-(2-chlorophenyl)-1-hydroxypropyl-2-N-cyclohexylcarbamate, 1-(2-chlorophenyl)-1-hydroxypropyl-2-N-benzylcarbamate, 1-(2-chlorophenyl)-1-hydroxypropyl-2-N-bicyclo[2,2,1]heptanecarbamate, 1-(2,4-dichlorophenyl)-1-hydroxypropyl-2-carbamate, 1-(2,6-dichlorophenyl)-1-hydroxypropyl-2-carbamate, 1-(2,4-dichlorophenyl)-1-hydroxy-3-methyl-butyl-2-carbamate, 1-(2,6-dichlorophenyl)-1-hydroxy-3-methyl-butyl-2-carbamate, 1-(2,4-dichlorophenyl)-1-hydroxyhexyl-2-carbamate, 1-(2,6-dichlorophenyl)-1-hydroxyhexyl-2-carbamate, 1-(2-chlorophenyl)-2-hydroxypropyl-1-carbamate, 1-(2-chlorophenyl)-2-hydroxypropyl-1-N-methylcarbamate, 1-(2-chlorophenyl)-2-hydroxypropyl-1-N-propylcarbamate, 1-(2-chlorophenyl)-2-hydroxypropyl-1-N-isopropylcarbamate, 1-(2-chlorophenyl)-2-hydroxypropyl-1-N-cyclopropylcarbamate, 1-(2-chlorophenyl)-2-hydroxypropyl-1-N-cyclohexylcarbamate, 1-(2-chlorophenyl)-2-hydroxypropyl-1-N-benzylcarbamate, 1-(2,4-dichlorophenyl)-2-hydroxypropyl-1-carbamate, 1-(2,6-dichlorophenyl)-2-hydroxypropyl-1-carbamate, 1-(2,4-dichlorophenyl)-2-hydroxybutyl-1-carbamate, 1-(2,4-dichlorophenyl)-2-hydroxy-3-methyl-butyl-1-carbamate, 1-(2,6-dichlorophenyl)-2-hydroxy-3-methyl-butyl-1-carbamate, 1-(2,4-dichlorophenyl)-2-hydroxyhexyl-1-carbamate, 1-(2,6-dichlorophenyl)-2-hydroxyhexyl-1-carbamate, 1-(2-fluorophenyl)-1-hydroxypropyl-2-carbamate, 1-(2-iodophenyl)-1-hydroxypropyl-2-carbamate, 1-(2-iodophenyl)-1-hydroxybutyl-2-carbamate, 1-(2,3-dichlorophenyl)-1-hydroxypropyl-2-carbamate, and 1-(2,3-dichlorophenyl)-2-hydroxypropyl-1-carbamate; or a pharmaceutically acceptable salt thereof, wherein the compound is in the form of racemate, enantiomer, diastereomer, a mixture of enantiomer, or a mixture of diastereomer.