Patent ID: 6329502
Filing Date: 2001-12-11
Classification: C07K

Abstract:
A compound represented by the formula (3') or a salt thereof: ##STR21##wherein:A represents a hydrogen atom or a peptide N-terminal blocking group, wherein said blocking group is selected from the group consisting of aryloxyacetyl moieties, heteroaryloxyacetyl moieties, 3-phenylpropionyl, quinoline-2-carbonyl), tert-butoxycarbonyl and benzyloxycarbonyl,B.sup.1, B.sup.2, B.sup.3, B.sup.5 and B.sup.6 independently represents a single bond or an amino acid residue and optionally the amino group of said amino acid is substituted with a hydrocarbon group having 12 or fewer carbon atoms,X represents a nitrogen atom,R.sup.1 represents a benzyl or a cyclohexylmethyl group,R.sup.2 and R.sup.3 each represent a hydrogen atom or a hydrocarbon group having 12 or fewer carbon atoms which may form a cyclic ring together with the nitrogen atom to which they are attached, wherein said hydrocarbon group may optionally be substituted with hydroxyl groups, andR.sup.6 represents a bivalent hydrocarbon group which, together with the nitrogen atom and methine carbon to which it is attached, forms a ring system selected from pyrrolidine, thiazolidine, indoline, octahydroindole, piperidine, 1,2,3,4-tetrahydroisoquinoline or decahydroisoquinoline, wherein the ring system is optionally substituted with a hydroxyl group, a methoxy group, an ethoxy group, an allyloxy group, a benzyloxy group, a phenyl group, or methyl groups.