Patent ID: 8846631
Filing Date: 2014-09-30
Classification: A61K,C12N

Abstract:
1. A method of treating liver cancer comprising intravenously administering to a subject having liver cancer a composition comprising an oligomeric compound comprising a first oligonucleotide consisting of 19 to 23 linked nucleosides, wherein the nucleobase sequence of the first oligonucleotide has at least 90% identity with the nucleobase sequence of SEQ ID NO: 1 with 100% identity with nucleobases 2 to 7 of SEQ ID NO: 1, wherein the oligomeric compound comprises a second oligonucleotide hybridized to the first oligonucleotide, wherein the second oligonucleotide consists of 19 to 23 linked nucleosides and wherein the second oligonucleotide is complementary to the first oligonucleotide, and wherein the oligomeric compound is formulated in a liposome.