Patent ID: 6150343
Filing Date: 2000-11-21
Classification: A61K,A61P,C07D,C07F

Abstract:
A compound having the structure: ##STR26## wherein R.sup.1 is hydrogen, an alkyl group, an alkenyl group, an alkynyl group, an alkoxyl group, an aryloxy group, a carbamoyloxy group, a halogen, a hydroxyl group, a nitro group, a cyano group, an azido group, a formyl group, a hydrazino group, --C(O)R.sup.f, wherein R.sup.f is an alkyl group, a haloalkyl group, an alkoxyl group, an amino group or a hydroxyl group, an amino group, --SR.sup.c, wherein R.sup.c is hydrogen, --C(O)R.sup.f, an alkyl group, or an aryl group, --OC(O)R.sup.d or --OC(O)OR.sup.d, wherein R.sup.d is an alkyl group;R.sup.2 is a hydroxyl group;R.sup.3 is H, F, a halogen atom, a nitro group, an amino group, a hydroxyl group, or a cyano group;R.sup.4 is H, F, a C.sub.1-3 alkyl group, a C.sub.2-3 alkenyl group, a C.sub.2-3 alkynyl group, or a C.sub.1-3 alkoxyl group;R.sup.5 is a C.sub.1-10 alkyl group, or a propargyl group; and R.sup.6, R.sup.7 and R.sup.8 are independently a C.sub.1-10 alkyl group, a C.sub.2-10 alkenyl group, a C.sub.2-10 alkynyl group, an aryl group or a --(CH.sub.2).sub.N R.sup.9 group, wherein N is an integer within the range of 1 through 10 and R.sup.9 is a hydroxyl group, alkoxy group, an amino group, an alkylamino group, a dialkylamino group, a halogen atom, a cyano group or a nitro group;and pharmaceutically acceptable salts thereof.