Patent ID: 6734306
Filing Date: 2004-05-11
Classification: A61P,C07D

Abstract:
A compound of the formula (I): or a pharmaceutically acceptable salt thereof whereinX1 and X2 are independently halo or C1-4 alkyl; R1 and R2 are independently hydrogen or C1-4 alkyl; R3 and R4 are independently hydrogen or halo; and R5 is (a) â€”C3-9 diazacycloalkyl optionally substituted with C5-11 azabicycloalkyl; (b) â€”C3-9 azacycloalkyl-NHâ€”(C5-11 azabicycloalkyln optionally substituted with C1-4 alkyl); (c) â€”NHâ€”C1-3 alkyl-C(O)â€”C5-11 diazabicycloalkyl; (d) â€”NHâ€”C1-3 alkyl-C(O)â€”C4-9 azabicycloalkyl, the â€”C5-11 azabicycloalkyl being optionally substituted with C1-4 alkyl; (e) â€”C3-9 azacycloalkyl optionally substituted with C3-9 azacycloalkyl; or (f) â€”NHâ€”C1-5 alkyl-NHâ€”C(O)â€”C4-9 cycloalkyl-NH2.