Patent ID: 8372582
Filing Date: 2013-02-12
Classification: A61P,G01N

Abstract:
1. A method of diagnosing or predicting risk of developing diabetic retinopathy, or diabetic nephropathy, or both, in a subject, the method comprising: identifying a subject suspected to have or be at risk of developing diabetic retinopathy, or diabetic nephropathy, or both; obtaining a biological sample from the subject; determining a level of SHP-1 protein or mRNA in the sample; and comparing the level of SHP-1 protein or mRNA in the sample to a predetermined reference level of SHP-1 protein or mRNA, wherein a level of SHP-1 protein or mRNA that is above the reference level indicates that the subject has or is at risk of developing diabetic retinopathy, or diabetic nephropathy, or both.