Patent ID: 8883781
Filing Date: 2014-11-11
Classification: A61P,C07D

Abstract:
1. A compound of formula I-A-i: or a pharmaceutically acceptable salt thereof, wherein: R wherein the ring formed by R Ring A is; each occurrence of R each occurrence of R is independently hydrogen or a C each occurrence of R′ is independently hydrogen, a C provided that: Ring A is Ring A2 and R B. when R optionally and independently substituted at one or more substitutable carbon, nitrogen, or sulfur atoms with z independent occurrences of —R 4 , z is 0-5, Ring A is either Ring A1 or Ring A2, either one or both of R 3A and R 3B is Q-R X and Q is a bond or a C 1 alkylidene chain, then R X is not —N(R′) 2 ; and C. when Ring A is Ring A2, R