Patent ID: 6080886
Filing Date: 2000-06-27
Classification: C07B,C07C

Abstract:
A method for the fluorination of a compound selected from the group consisting of alcohols, aldehydes, ketones, epoxides and mixtures thereof using a fluorinating reagent comprising contacting said compound with said fluorinating reagent under conditions sufficient to fluorinate said compound wherein said fluorinating reagent is an aminosulfur trifluoride composition having a structure with one or more: ##STR68## wherein m=1-5 and R.sup.1 and R.sup.2 are: (1) when m=1, one of R.sup.1 and R.sup.2 is an aryl radical and the other is an at least 5 member saturated cyclic hydrocarbon radical having one to three heteroatoms selected from the group consisting of oxygen; or(2) when m=1, one of R.sup.1 and R.sup.2 is an aryl radical and the other is an at least 5 member saturated cyclic hydrocarbon radical having one to three heteroatoms selected from the group consisting of oxygen wherein said cyclic hydrocarbon radical is fused to said aryl radical; or(3) when m=1, R.sup.1 and R.sup.2 an together a cyclic ring having 2 to 10 carbon ring members and 1 heteroatom selected from the group consisting of oxygen, nitrogen and alkylated nitrogen wherein said ring has 1 to 2 alkoxyalkyl functionalities; or(4) when m=1, R.sup.1 and R.sup.2 an together an unsaturated cyclic ring having 2 to 4 carbon ring members and one to three heteroatoms selected from the group consisting of oxygen, nitrogen, protonated nitrogen and alkylated nitrogen wherein said ring has one to three functional groups of alkoxy; or(5) when m=1, individually alkoxyalkyl radicals; or(6) when m=1, one of R.sup.1 and R.sup.2 is alkoxyalkyl and the other is selected from the group consisting of alkyl and aryl radicals; or.