Patent ID: 8802626
Filing Date: 2014-08-12
Classification: A61F,A61K,A61L,A61P,C07K

Abstract:
1. A device for inducing local bone or cartilage formation, comprising: an osteogenic protein selected from the group consisting of OP-1, OP-2, OP-3, BMP3, BMP4, BMP5, BMP6, BMP9, BMP10, BMP11, BMP12, BMP15, BMP16, DPP, Vgl, Vgr, 60A protein, GDF1, GDF3, GDF5, GDF6, GDF7, GDF8, GDF9, GDF10, and GDF11; a matrix selected from the group consisting of collagen, demineralized bone, apatites, hydroxyapatites, tricalcium phosphates, and admixtures thereof; and a low viscosity grade of an alkylcellulose; wherein when the alkylcellulose is carboxymethylcellulose, said carboxymethylcellulose has a viscosity of 10-200 cP at a concentration of 4% (w/v); and wherein the ratio of the alkylcellulose to the matrix in said device is 1 part by weight alkylcellulose to 2-10 parts by weight matrix.