Patent ID: 8501490
Filing Date: 2013-08-06
Classification: C12Q,Y10T

Abstract:
1. A polymeric sequence probe (PSP) for detection of a first target analyte which PSP comprises a macromolecular backbone, along which is disposed a first multiplicity of recognition sites specific for said first target analyte and a multiplicity of labels or label sites wherein at least three of said recognition sites are disposed linearly along said backbone; and wherein said PSP is not bound to analyte and further contains (a) a multiplicity of detectable labels; or (b) a labeling microparticle or nanoparticle coupled to said macromolecular backbone, or (c) a combination of a and b; or wherein the macromolecular backbone of said PSP is dendritic or circular; or wherein the macromolecular backbone of said PSP is a protein or a multi-functional organic polymer; or wherein the recognition sites of said PSP are regions of said backbone that are aptamers specific for target analyte; or wherein the recognition sites or label sites are covalently coupled to the macromolecular backbone; or wherein the recognition sites or label sites comprise antibodies or fragments thereof immunospecific for said target analyte; or wherein the recognition sites comprise ligands and the target analyte is a receptor or wherein said recognition sites comprise receptors and the target analyte is a ligand.