Patent ID: 7144457
Filing Date: 2006-12-05
Classification: C30B

Abstract:
1. A method for evaluating a crystallization experiment comprising: exposing a given location of a crystallization experiment of a molecule to X rays multiple times while the crystallization experiment is housed within a container in which the crystallization experiment is performed where the angle of the x-ray beam is varied relative to the crystallization experiment among the different X-ray exposures; and using one or more X-ray diffraction patterns formed from the multiple X-ray exposures to evaluate whether crystalline material is present in the crystallization experiment, wherein the crystallization experiment is crystallizing a molecule selected from the group consisting of a macromolecule, a protein, a molecule with a molecular weight of at least 500 Daltons, a molecule with a molecular weight of at least 1000 Daltons, and a protein.