Patent ID: 8557562
Filing Date: 2013-10-15
Classification: C12N,C12P,Y02E

Abstract:
1. A recombinant yeast cell comprising: (a) an isobutanol biosynthetic pathway, wherein the recombinant yeast cell comprises heterologous genes encoding an acetolactate synthase, an acetohydroxy acid isomeroreductase, an acetohydroxy acid dehydratase or dihydroxyacid dehydratase, a branched-chain keto acid decarboxylase, and a branched-chain alcohol dehydrogenase that perform the following substrate to product conversions: (b) at least one genetic modification which increases activity of the nitrogen starvation-induced filamentous growth response, wherein the genetic modification is heterologous expression of a transcription factor involved in regulation of invasive growth in response to nutritional signals, wherein the transcription factor has at least 95% sequence identity to the