Patent ID: 9144602
Filing Date: 2015-09-29
Classification: A61K,A61P,C12Y

Abstract:
1. A method comprising: obtaining a composition comprising crystalline xylose-isomerase (EC 5.3.1.5) which originates from a microorganism of the family of Streptomycetaceae co-crystallized with a magnesium salt and at least one bivalent metal salt selected from the group consisting of cobalt salt, zinc salt, iron salt and copper salt, wherein the composition comprises a molar ratio of the bivalent metal salt selected from the group consisting of cobalt salt, zinc salt, iron salt and copper salt to xylose-isomerase ranging from 3:1 to 7:1; and wherein the composition further comprises a molar ratio of the magnesium salt to xylose-isomerase ranging from 5:1 to 200:1; and administering the composition to a subject suffering from symptoms correlated with oral fructose malabsorption.