Patent ID: 8323953
Filing Date: 2012-12-04
Classification: C12M,C12Q,G01N

Abstract:
1. A detection device to detect biological micro particles, comprising: a filter disposed between a first sub chamber and a second sub chamber in a detection chamber, the filter being configured to filter out micro particles to be detected from a fluid to be measured; a supply system including a first inlet conduit fluidically coupled to the first sub chamber and a second inlet conduit fluidically coupled to the second sub chamber, a first valve configured to selectively connect one of a plurality of sources of chemicals to an outlet connection to supply to the outlet connection at least one respective chemical from the one of the sources, first and second pumps, each with a different pumping capacity, connected to the outlet connection and configured to provide the respective chemical to a valve inlet, and a second valve configured to selectively provide the respective chemical from the valve inlet to one of the first and second sub chambers via one of the first and second inlet conduits to mark the micro particles to be detected with probes, the probes being radiation emitting nucleic acid probes or radiation emitting proteins, and the supply system being further configured to operate the first valve, the first and second pumps, and the second valve to selectively supply at least one other of the chemicals from at least one of the plurality of sources to one of the first and second sub chambers via one of the first and second inlet conduits to regenerate the filter and to supply cleaning agents or conditioning agents through or to the filter; a discharge system including a first outlet conduit fluidically coupled to the first sub chamber and a second outlet conduit fluidically coupled to the second sub chamber, the discharge system being configured to selectively fluidically couple one of the first and second sub chambers to a discharge outlet via one of the first and second outlet conduits based on the one of the first and second sub chambers to which the supply system is supplying the respective chemical; and a detection system being configured to detect the probes through the detection of radiation emitted by the probes.