Patent ID: 7977338
Filing Date: 2011-07-12
Classification: A61P,C07D

Abstract:
1. A compound of formula (I) wherein (i) each of R1 and R2, independently of the other, is selected from the group consisting of hydrogen, halo and C wherein (a) R4 is hydrogen, halo, unsubstituted or substituted amino, unsubstituted or substituted aryl, unsubstituted or substituted heterocyclyl bound via a ring atom other than nitrogen, unsubstituted or substituted cycloalkyl, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl or unsubstituted or substituted alkynyl; (b)R4 is 1-methyl-piperidin-4-ylmethyl), 1-ethyl-piperidin-4-ylmethyl, 1-methyl-piperidin-4-yloxy or 1-isopropyl-piperidin-4-ylmethyl; where the asterisk * in formula (A) marks the bond through which the moiety is bound to the NH of the amide group in formula (I); and either each of R9 and R10, independently of the other, is selected from the group consisting of hydrogen, hydroxyl and C R9 and R10 together represent oxo; or R1 and R9 together form a group —C(O)—CH2— or —CH2—CH2—, R2 is selected from the group consisting of hydrogen, halo and C or (ii) which is selected from the group consisting of N-[3-(4-Ethyl-piperazin-1-ylmethyl)-5-trifluoromethyl-phenyl]-2-(4-imidazo[4,5-b]pyridin-3-yl-phenyl)-acetamide,