Patent ID: 6114550
Filing Date: 2000-09-05
Classification: C07C,C07D,Y02P

Abstract:
A .beta.-phenylisoserine derivative of general formula (I): ##STR14## in the form of a salt or an ester, in which: Ar represents an aryl radical;R represents a phenyl or .alpha.- or .beta.-naphthyl radical unsubstituted or substituted with one or more identical or different atoms or radicals selected from halogen atoms, alkyl radicals containing 1 to 4 carbon atoms, and alkoxy radicals containing 1 to 4 carbon atoms, or a radical R.sub.1 --O in which R.sub.1 represents:an unbranched or branched alkyl radical containing 1 to 8 carbon atoms, an alkenyl radical containing 2 to 8 carbon atoms, an alkynyl radical containing 3 to 8 carbon atoms, a cycloalkyl radical containing 3 to 6 atoms, a cycloalkenyl radical containing 4 to 6 carbon atoms, or a bicycloalkyl radical containing 7 to 11 carbon atoms, these radicals unsubstituted or substituted with one or more substituents selected from halogen atoms, hydroxyl radicals, alkyloxy radicals containing 1 to 4 carbon atoms, dialkylamino radicals in which each alkyl portion contains 1 to 4 carbon atoms, piperidino radicals, morpholino radicals, 1-piperazinyl radicals (unsubstituted or substituted at position 4 with an alkyl radical containing 1 to 4 carbon atoms or with a phenylalkyl radical in which the alkyl portion contains 1 to 4 carbon atoms), cycloalkyl radicals containing 3 to 6 carbon atoms, cycloalkenyl radicals containing 4 to 6 carbon atoms, phenyl radicals, cyano radicals, carboxyl radicals, and alkoxycarbonyl radicals in which the alkyl portion contains 1 to 4 carbon atoms, wherein the cycloalkyl, cycloalkenyl, or bicycloalkyl radicals can be unsubstituted or substituted with one or more alkyl radicals containing 1 to 4 carbon atoms;a phenyl or .alpha.- or .beta.-naphthyl radical unsubstituted or substituted with one or more atoms or radicals selected from halogen atoms, alkyl radicals containing 1 to 4 carbon atoms, or alkyloxy radicals containing 1 to 4 carbon atoms; ora saturated or unsaturated 4- to 6-membered nitrogenous heterocyclic radical unsubstituted or substituted with one or more alkyl radicals containing 1 to 4 carbon atoms;and G.sub.1 represents a --CH.sub.2 --Ph radical in which Ph represents a phenyl radical unsubstituted or substituted with one or more identical or different atoms or radicals selected from halogen atoms and alkyl radicals containing 1 to 4 carbon atoms or alkoxy radicals containing 1 to 4 carbon atoms.