Patent ID: 8940318
Filing Date: 2015-01-27
Classification: A61F,A61K,A61P,G02B,G02C,Y10S

Abstract:
1. A daily disposable hydrogel contact lens for sustained drug release of sustainedly releasing a dose of an anionic drug, wherein the amount of initial release in a time period of about 4 hours after the start of wearing the hydrogel contact lens is not more than 50% of the dose of the anionic drug contained in the hydrogel contact lens, and not less than 80% of the dose of the anionic drug contained in the hydrogel contact lens is released at least in 14 hours after the start of wearing the hydrogel contact lens; and the hydrogel contact lens comprises at least: (a) an anionic drug, (b) a combination of (i) and (ii) as hydrophilic monomers wherein (i) is either hydroxymethyl (meth)acrylate or 2-hydroxyethyl (meth)acrylate and (ii) is either 2-hydroxypropyl (meth)acrylate or 2,3-dihydroxypropyl (meth)acrylate, and (c) ionic monomers including a cationic monomer and an anionic monomer, the component ratio of the ionic monomers is not less than 5 mol % and not more than 20 mol % relative to the total quantity of the monomers composed in the hydrogel, and the content ratio of the anionic monomer is 15 mol % to less than 25 mol % relative to the cationic monomer.