Patent ID: 7285551
Filing Date: 2007-10-23
Classification: A61K,A61P,C07D,C07H

Abstract:
1. A fused ring compound of the following formula wherein the moiety is a fused ring selected from  wherein R 1 , R 2 , R 3 and R 4 are each independently, (1) hydrogen atom, (2) C (3) carboxyl, (4) cyano, (5) nitro, (6) C (7) —COOR (8) —CONR (9) —C(═NR (10) —NHR (11) —OR (12) —SO (13) —P(═O)(OR (14) heterocyclic group having 1 to 4 heteroatom(s) selected from an oxygen atom, a nitrogen atom and a sulfur atom, and ring Cy′ is (1) C (2)  wherein u and v are each independently an integer of 1 to 3, ring A′ is a group selected from a group consisting of phenyl, pyridyl, pyrazinyl, pyrimidinyl, pyridazinyl, cyclohexyl, cyclohexenyl, furyl, and thienyl, R 5′ and R 6′ are each independently (1) hydrogen atom, (2) halogen atom, (3) optionally substituted C (4) hydroxyl group ring B is (1) C (2) C (3) heterocyclic group having 1 to 4 heteroatom(s) selected from an oxygen atom, a nitrogen atom and a sulfur atom, each Z is independently (1) a group selected from the following group D, (2) C (3) C (4) C (5) heterocyclic group optionally substituted by 1 to 5 substituent(s) selected from the following group D wherein the hetero cyclic group has 1 to 4 heteroatom(s) selected from an oxygen atom, a nitrogen atom and a sulfur atom, or (6) heterocycle C w is an integer of 1 to 3, and Y is (1) a single bond, (2) C (3) C (4) —CO—, (5) —CO (6) —CONH—(CH (7) —NHCO (8) —NHCONH—, (9) —O—(CH (10) —SO (11) —(CH (12) —NR (13) —CONR (14) —CONH—CHR (15) —O—(CH (16) —(CH (17) —NR (18) —S(O) (19) —(CH or a pharmaceutically acceptable salt thereof.