Patent ID: 8389711
Filing Date: 2013-03-05
Classification: A61K,A61P,C12N

Abstract:
1. A small interfering RNA (siRNA) molecule that directs cleavage of mRNA of mucin subtype 5 AC via RNA interference, wherein a target mRNA region of the RNA interference is selected from the group consisting of an mRNA region consisting of a nucleotide sequence of SEQ ID NO:1, an mRNA region consisting of a nucleotide sequence of SEQ ID NO:3, an mRNA region consisting of a nucleotide sequence of SEQ ID NO:5, an mRNA region consisting of a nucleotide sequence of SEQ ID NO:7, an mRNA region consisting of a nucleotide sequence of SEQ ID NO:9, an mRNA region consisting of a nucleotide sequence of SEQ ID NO:11, an mRNA region consisting of a nucleotide sequence of SEQ ID NO:16, and an mRNA region consisting of a nucleotide sequence of SEQ ID NO:21.