Patent ID: 7585847
Filing Date: 2009-09-08
Classification: A61K,C12N

Abstract:
1. A method for treating an asthmatic event in a hypo-responsive subject having allergic asthma, comprising: administering to a hypo-responsive subject having allergic asthma a CpG immunostimulatory nucleic acid having the formula wherein the cytosine of the CG dinucleotide is unmethylated, X 1 and X 2 are both purines and X 3 and X 4 are both pyrimidines, and N 1 and N 2 are nucleic acid sequences composed of 0-25 nucleotides each, in an effective amount for treating an asthmatic event, wherein the hypo-responsive subject is refractory to an asthma/allergy medicament, and wherein the CpG immunostimulatory nucleic acid is 8-100 nucleotides.