Patent ID: 6159954
Filing Date: 2000-12-12
Classification: A61K,A61P,C07H,C08B,C12P,Y10S

Abstract:
A method for therapeutic treatment of inflammation, comprising administering to a candidate for treatment an effective amount of a keratan sulfate oligosaccharide or pharmaceutically acceptable salt thereof, which has an oligosaccharide consisting of from two to five sugar units, said oligosaccharide having (a) no fucose, and (b) optionally sialic acid, to a patient suffering from inflammation in an effective amount, wherein said oligosaccharide further comprises, as a constitutional ingredient, at least disaccharide represented by the following formula:Gal(6S)-GlcNAc(6S)wherein Gal represents a galactose, GlcN represents a glucosamine, Ac represents an acetyl group, and 6S represents a 6-O-sulfate ester.