Patent ID: 6225312
Filing Date: 2001-05-01
Classification: A61P,C07D

Abstract:
A compound having the formula (a) ##STR39##whereinA represents a heterocyclic group having 5-7 ring atoms in which 1-3 heteroatoms selected from the group O, N and S are present,R.sub.1 is hydrogen or fluoro,R.sub.2 is C.sub.1-4 -alkyl, C-.sub.1-4 -alkoxy or an oxo group, and p is 0, 1 or 2,Z represents nitrogen, and the dotted line represents a single bond,R.sub.3 and R.sub.4 independently are hydrogen or C.sub.1-4 -alkyl,n has the value 1,R.sub.5 is halogen, hydroxy, C.sub.1-4 -alkoxy or C.sub.1-4 -alkyl, and q is 0, 1, 2 or 3,Y is a phenyl, furanyl or thienyl group, which groups may be unsubstituted or substituted with 1-3 substituents selected from hydroxy, halogen, C.sub.1-4 -alkoxy, C.sub.1-4 -alkyl, cyano, aminocarbonyl, mono- and di-C.sub.1-4 -alkylaminocarbonyl, or a pharmacologically acceptable salt thereof.