Patent ID: 7335477
Filing Date: 2008-02-26
Classification: A61K,C07K,Y02A

Abstract:
1. An assay for detecting antibody to scrub typhus comprising: a) Obtaining a sample from a subject; and b) Exposing the sample to at least one polypeptide, selected from the group consisting of: an isolated polypeptide consisting of SEQ ID NO: 4, an isolated polypeptide consisting of SEQ ID NO: 5, or a combination thereof, said polypeptide or polypeptides being the refolded expressed product or products of truncated non-fusion r56 genes from c) Incubating said sample, wherein said antibody binds said at least one polypeptide forming a complex; d) Binding a detectable label to said complex wherein a detectable signal is produced; e) Detecting the signal, wherein the signal indicates the presence of said antibody.