Patent ID: 7556780
Filing Date: 2009-07-07
Classification: B01J,C07B,C07C

Abstract:
1. An automatic manufacturing device of 123 I-ADAM (Iodine-123 labeled 2-([2-dimethylamino]methyl)phenyl]thio)-5- 123 I-iodophenylamine), comprising: a central processing unit controlling the operation of said automatic manufacturing device; a plurality of reactant storage bottles, each of said plurality of reactant storage bottles containing a reactant selected from a group consisting of [ a reaction bottle containing a SnADAM ([2-((2-amino-4-tri-n-butyltinphenyl)thio)benzyl]dimethylamine) precursor and connected with the reactant storage bottles by a plurality of pipelines, each of said plurality of pipelines being disposed with a respective solenoid valve, said central processing unit being coupled to each said respective solenoid valve to control an order and duration of supply of the reactants from said plurality of reactant storage bottles to said reaction bottle to produce a a column connected to the output of said reaction bottle by a transport pipe to receive said an eluant storage bottle coupled to said column by an elution pipe, said eluant being added to said a first product storage bottle connected with the column to store said first product transported from said column through a first collection pipe; a filtering device connected with the first product storage bottle by a filtering pipe to filter said first product and to generate a purified a second product storage bottle connected with the filtering device by a second collection pipe to receive said purified