Patent ID: 7435386
Filing Date: 2008-10-14
Classification: B82Y,C12Q,G01N

Abstract:
1. A modular biosensor comprising: a biorecognition element, comprising a biorecognition module, said biorecognition module being labeled with a first signaling module, said biorecognition element being attached to a surface; a modular arm element, comprising of a flexible arm and a recognition module, said modular arm element being attached to a surface, wherein said modular arm element is labeled with a second signaling module, wherein said modular arm element is specifically oriented in reference to the biorecognition element, wherein said biorecognition module and said recognition module of said modular arm element bind, wherein said first and second signaling modules are in close proximity to each other to establish a baseline fluorescence resonance energy transfer (FRET); and a detector for detecting a change in FRET.