Patent ID: 9216241
Filing Date: 2015-12-22
Classification: A61K,A61L,Y10T

Abstract:
1. A medical device comprising: a substrate capable of forming hydroxyl groups, a biocompatible material layer, and a binder layer provided between the substrate and the biocompatible material layer formed through a dehydration-condensation reaction of at least one silicon alkoxide selected from the group consisting of methacryloyloxypropyltrimethoxysilane, methacryloyloxypropylmethyldimethoxysilane, methacryloyloxypropyltriethoxysilane, and acryloyloxypropyltrimethoxysilane, wherein: hydroxyl groups are formed on a surface of the substrate by a surface treatment, the biocompatible material layer is formed from a polymer containing phosphorylcholine groups, the substrate and the biocompatible material layer are joined via the binder layer , the binder layer is covalently bonded with the hydroxyl groups and the biocompatible material, only the binder layer contains a photopolymerization initiator, and the substrate is formed from at least one member selected from the group consisting of titanium, cobalt-chromium alloy, cobalt-chromium-molybdenum alloy, nickel-chromium alloy, stainless steel, and titanium base alloy.