Patent ID: 9157070
Filing Date: 2015-10-13
Classification: A61L,C07K,C12N,D01F

Abstract:
1. A combination, comprising: eukaryotic cells; and a cell scaffold material; wherein said cell scaffold material comprises a polymer comprising a spider silk protein and a cell-binding motif, said spider silk protein consisting of from 140 to 600 amino acid residues and comprising a repetitive fragment of from 70 to 300 amino acid residues derived from the repetitive fragment of a spider silk protein; a C-terminal fragment of from 70 to 120 amino acid residues derived from the C-terminal fragment of a spider silk protein; and optionally an N-terminal fragment of from 100 to 160 amino acid residues derived from the N-terminal fragment of a spider silk protein, wherein said cell-binding motif is an oligopeptide coupled to the spider silk protein via at least one peptide bond, and wherein said oligopeptide cell-binding motif is a keratinocyte-specific cell-binding motif.