Patent ID: 8153768
Filing Date: 2012-04-10
Classification: A61K,A61P,C07K

Abstract:
1. A composition comprising a drug conjugate, wherein said drug conjugate comprises calicheamicin derivatives and an antibody and has the formula: wherein the antibody comprises SEQ ID NO: 1 for CDR-H1, residues 50-66 of SEQ ID NO: 27 for CDR-H2, SEQ ID NO: 3 for CDR-H3, SEQ ID NO: 4 for CDR-L1, SEQ ID NO: 5 for CDR-L2 and SEQ ID NO: 6 for CDR-L3; wherein n is 3 to 9; and wherein the composition is less than 10% by weight of unconjugated antibody.