Patent ID: 6828142
Filing Date: 2004-12-07
Classification: B82Y,C12Q,G01N,Y10T

Abstract:
A composition comprising:fluorescent core/shell nanocrystal functionalized to be water soluble; said nanocrystal operably bonded to a plurality of polynucleotide strands of predetermined sequence, said polynucleotide strands of predetermined sequence able to hybridize under suitable conditions with complementary polynucleotide strands operably bonded to fluorescent core/shell nanocrystals functionalized to be water soluble, a terminal portion of each of the plurality of polynucleotide strands of predetermined sequence is operably linked to the nanocrystal functionalized to be water soluble, and wherein the opposite terminus of each of the plurality polynucleotide strands of predetermined sequence is unbound to the nanocrystal functionalized to be water soluble and extends outwardly therefrom.