Patent ID: 6040294
Filing Date: 2000-03-21
Classification: A61K,A61P,Y10S

Abstract:
A pharmaceutical formulation comprising a solution or suspension of i) an effective amount of an antimetabolite; and ii) a compound of the formula: ##STR6## wherein: R.sub.1 is hydrogen, lower alkyl or ##STR7## R.sub.2 and R.sub.4 are each individually SO.sub.3.sup.- M.sup.+, PO.sub.3.sup.2- M.sub.2.sup.2+, or PO.sub.2 S.sup.2- M.sub.2.sup.2+ ;R.sub.3 and R.sub.5 are each individually hydrogen, hydroxy or sulfhydryl;m and n are individually 0, 1, 2, 3 or 4, with the proviso that if m or n is 0, then R.sub.3 is hydrogen; andM is hydrogen or an alkali metal ion; ora pharmaceutically acceptable salt thereof, and one or more pharmaceutically acceptable carriers, excipients or diluents.