Patent ID: 7700624
Filing Date: 2010-04-20
Classification: A61P,C07D

Abstract:
1. A compound of Formula I: or pharmaceutically acceptable salts or prodrugs thereof, wherein: a dashed line indicates an optional bond; W is: V is N, NO or CR X is N, NO or CR Y is N, NO or CR Z is N, NO or CR L is C R R R R R Y and Z are independently selected from —O—, —NR R R or R R or R or R or R R R R R Cy and Cy′ are, independently, aryl, heteroaryl, cycloalkyl, or heterocycloalkyl, each optionally substituted by 1,2,3,4 or 5 substituents independently selected from oxo, hydroxy, halo, C R R R R R C 1-6 haloalkyl, C 2-6 alkenyl, C 2-6 alkynyl, aryl, cycloalkyl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, cycloalkylalkyl or heterocycloalkylalkyl is optionally substituted with 1, 2, or 3 substituents independently selected from OH, amino, halo, C 1-6 alkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, cycloalkyl and heterocycloalkyl; R C 1-6 haloalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, cycloalkyl and heterocycloalkyl; R C 1-6 haloalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, cycloalkyl and heterocycloalkyl; or R R or R R or R m is 0, 1, or 2; n is 1; p is 0 or 1; and q is 0, 1, 2, or 3.