Patent ID: 7560438
Filing Date: 2009-07-14
Classification: A01K,A61K,A61P,C12N

Abstract:
1. A method to inhibit expression of a target gene in a cell in a multicellular animal comprising providing at least one ribonucleic acid (RNA) to the cell in an amount sufficient to inhibit the expression of the target gene, wherein the RNA comprises or forms a double-stranded structure containing a first strand consisting essentially of a ribonucleotide sequence which corresponds to a nucleotide sequence of the target gene and a second strand consisting essentially of a ribonucleotide sequence which is complementary to the nucleotide sequence of the target gene, wherein the first and the second ribonucleotide sequences are separate complementary sequences that hybridize to each other to form said double-stranded structure, and the RNA comprising the double-stranded structure inhibits expression of the target gene, and wherein said animal is selected from the group consisting of worms and insects.