Patent ID: 6596773
Filing Date: 2003-07-22
Classification: A61P,C07C,C07D

Abstract:
A compound of the general formula whereinR is hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl; R1 is hydrogen or halogen; or R and R1 may be together â€”CH&boxH;CHâ€”CH&boxH;CHâ€”; R2 is hydrogen, halogen, trifluoromethyl, lower alkoxy or cyano; R3 is independently from each other hydrogen, lower alkyl or form a cycloalkyl group; R4 is hydrogen, halogen, lower alkyl, or lower alkoxy; R5 is, independently from each other, hydrogen, C3-6-cycloalkyl, benzyl or lower alkyl; X is â€”N(R5)C(O); Y is â€”Oâ€”, â€”Sâ€”, or â€”SO2; Z is â€”CH&boxH; or â€”C(Cl)&boxH;; and n is 0-4; and pharmaceutically acceptable acid addition salts thereof.