Patent ID: 9125883
Filing Date: 2015-09-08
Classification: A61K,A61P,C08B,C12N

Abstract:
1. A method for selectively stimulating the proliferation of adult mesenchymal stem cells, comprising a step of: contacting a cell sample comprising adult mesenchymal stem cells with a low-molecular-weight sulfated polysaccharide derivative, wherein said low-molecular-weight sulfated polysaccharide derivative:  is obtained by a process comprising: a step consisting of free-radical depolymerisation of said native EPS so as to obtain a depolymerized derivative of low molecular weight, less than or equal to 100,000 g/mol, and a subsequent step consisting of sulfation of the depolymerized derivative, comprising adding to the depolymerised derivative at least one sulfation agent in an amount sufficient to obtain a sulfated polysaccharide derivative having a degree of sulfate group substitution of between 10% and 45% by weight relative to the total weight of the sulfated polysaccharide derivative.