Patent ID: 7387772
Filing Date: 2008-06-17
Classification: A61K,A61P,B82Y,C07K,Y10S

Abstract:
1. A monoclonal (MAb) antibody or immunoreactive fragment thereof that binds to the Mu-9 epitope of a colon-specific antigen-p mucin (CSAp) antigen, comprising the framework (FR) regions of the light and heavy chain variable regions of a human antibody and the light and heavy chain constant regions of a human antibody, wherein the light chain variable region of said antibody comprises CDR1 (RSSQSIVHSNGNTYLE, SEQ ID NO:1), CDR2 (KVSNRFS, SEQ ID NO:2), and CDR3 (FQGSRVPYT, SEQ ID NO:3), and wherein the heavy chain variable region comprises CDR1 (EYVIT, SEQ ID NO:4), CDR2 (EIYPGSGSTSYNEKFK, SEQ ID NO:5), and CDR3 (EDL).