Patent ID: 6440960
Filing Date: 2002-08-27
Classification: A61P,C07D

Abstract:
A compound having the following structure: or a stereoisomer, prodrug or pharmaceutically acceptable salt thereof,wherein:X is nitrogen or CR3; Y is O or S(O)0-2; â€œ- - - â€  represents an option double bond; A and C are the same or different and independently nitrogen, carbon or CH; B is nitrogen or CR4; with the provisos that at least one of A, B or C is nitrogen, A, B and C are not all nitrogen, and either Aâ€”B or Bâ€”C is a double bond; R is an optional substituent which, at each occurrence, is independently alkyl, substituted alkyl, aryl, arylalkyl, alkylidenyl, heterocycle, heterocyclealkyl, alkoxy or â€”CO(alkoxy), wherein m is 0, 1, 2 or 3 and represents the number of R substituents; R1 is alkyl, substituted alkyl, aryl, substituted aryl, heteroaryl or substituted heteroaryl; R2 is hydrogen, alkyl, alkoxy or thioalkyl or haloalkyl; R3 is hydrogen, alkyl, halogen or haloalkyl; and R4 is hydrogen, halogen, alkyl, alkoxy, thioalkyl or haloalkyl.