Patent ID: 7115381
Filing Date: 2006-10-03
Classification: G01N

Abstract:
1. A method for identifying a compound that binds to and/or modulates the activity of a Kv4.2 or Kv4.3 potassium channel by binding to and/or modulating the activity of a PCIP polypeptide comprising: a) contacting a 9q PCIP polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NOs: 14, 16, 18, 20, 22, 24, 26, and 28, or a cell expressing said 9q PCIP polypeptide, with a test compound; and b) determining whether said test compound binds to and/or modulates the activity of said 9q PCIP polypeptide, wherein said activity is selected from the group consisting of regulation of I