Patent ID: 6906090
Filing Date: 2005-06-14
Classification: A61K,A61P

Abstract:
1. A method of treating a patient suffering from, or at risk of, mycobacterial tuberculosis, which comprises administering to the patient a therapeutically effective amount of a compound of formula (I), or a pharmaceutically-acceptable salt or solvate thereof, wherein x represents 0 or 1, R 1 represents a 3- to 7-membered (hetero)cycloalkyl group or a phenyl group, Y represents a group CH 2 or >C═O, and R 2 represents either a C 1 -C 12 alkyl group optionally substituted by one or more halogen atoms, a group wherein m represents an integer from 3 to 7, R 3 represents a C R C or a group wherein n represents an integer from 2 to 4, p and q independently represent an integer from 1 to 2, Z represents N or CH and R 5 represents a cyclohexyl or phenyl group optionally substituted by one or more substituents selected from the group consisting of a halogen atom, C 1 -C 6 alkyl and C 1 -C 6 alkoxy group.