Patent ID: 6143766
Filing Date: 2000-11-07
Classification: C07D

Abstract:
A compound having the Formula I: ##STR69## and the pharmaceutically acceptable salts thereof, wherein X is --N--R.sup.3 or O;R.sup.2 is alkyl, alkenyl, aryl, substituted aryl, aralkyl, substituted aralkyl, heteroaryl, substituted heteroaryl, heteroaralkyl, or substituted heteroaralkyl;R.sup.3 is hydrogen, alkyl, alkenyl, aralkyl, substituted aralkyl, aryl, or substituted aryl;R.sup.4 is hydrogen, alkyl, alkenyl, aryl, substituted aryl, aralkyl, substituted aralkyl, heteroaralkyl, or substituted heteroaralkyl;one of R.sup.5 and R.sup.6 is hydrogen, and the other is --O--R.sup.1 ;R.sup.1 is ##STR70## R.sup.7 is hydrogen, alkyl, aralkyl or substituted aralkyl; and R.sup.8 and R.sup.9 are independently hydrogen, alkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, aralkyl, or substituted aralkyl;provided, however, that when R.sup.2 is hydrogen or C.sub.1 -C.sub.6 alkyl, X is O, R.sup.4 is hydrogen, R.sup.5 or R.sup.6 is --O--R.sup.1, and R.sup.1 is ##STR71## then, R.sup.7, R.sup.8, and R.sup.9 are not all hydrogen.