Patent ID: 6355642
Filing Date: 2002-03-12
Classification: A61P,C07D

Abstract:
A compound represented by formula (I): wherein A represents N, CH, C having a double bond or CR5; each of B and Z independently represents N or CR1, with the proviso that A is N when B and/or Z is N; R1 represents a hydrogen atom, a halogen atom, a lower alkyl group, a cyano group, a trihalomethyl group, a hydroxy group, an alkoxy group, an alkylthio group, an alkylsulfinyl group, an alkylsulfonyl group, an alkoxycarbonyl group, a sulfamoyl group, an amino group, a substituted amino group, a carbamoyl group, an alkylcarbamoyl group, an acyl group or a carboxy group; R2 represents a hydrogen atom or a lower alkyl group; R3 represents a hydrogen atom, a lower alkyl group or an aralkyl group; R4 represents a hydrogen atom, a halogen atom, a lower alkyl group, a hydroxy group, an alkoxy group, an acyl, an alkoxycarbonyl group, a nitro group, an amino group, a substituted amino group, a carbamoyl group, an alkylcarbamoyl group or an acyloxy group; R5 represents a lower alkyl group, a cyano group, a carbamoyl group, a carboxy group, an acyl group, an acyloxy group, an alkoxy group, an alkoxycarbonyl group, a trihalomethyl group or a hydroxy group; and n is an integer of 2 to 6 or a pharmaceutically acceptable salt thereof.