Patent ID: 7939269
Filing Date: 2011-05-10
Classification: A61P,C07K,C12N,G01N

Abstract:
1. A method for detecting prostate cancer, colon cancer, lung cancer, gastric cancer, breast cancer, skin cancer, and/or brain tumor in a subject, comprising obtaining a sample suspected of containing cancer cells from the subject; contacting the sample with an antibody which recognizes Epstein-Barr virus nuclear antigen 2 coactivator p100 (EBNA2 coactivator p100) and specifically binds to at least an amino acid sequence of RPASPATETVPAFSERTC (SEQ ID NO. 1), an amino acid sequence DDDARTDAVDSVVR (SEQ ID NO. 2), or a partial sequence thereof; detecting a presence of a specific interaction between the antibody and an antigen in the sample and comparing that interaction to a control non-cancerous sample, wherein the presence of the interaction that is increased compared to the control non-cancerous sample is indicative of cancer in the subject wherein the cancer is an advanced cancer not an insignificant cancer.