Patent ID: 6673916
Filing Date: 2004-01-06
Classification: A61K,C07K,C12N,G01N

Abstract:
A composition comprising an excipient and an isolated nucleic acid molecule that hybridizes to a nucleic acid molecule fully complementary to a nucleic acid molecule selected from the group consisting of SEQ ID NO:1, SEQ ID NO:3, SEQ ID NO:4, and SEQ ID NO:6 under conditions comprising: (i) hybridizing in 5Ã—SSPE and 1% sarkosyl at 37Â° C., and (ii) washing in 5Ã—SSPE and 1% sarkosyl at room temperature followed by one wash each in 1Ã—SSPE and 0.1% SDS at each of the following temperatures, room temperature, followed by 37Â° C., followed by 42Â° C., followed by 45Â° C., wherein said hybridizing nucleic acid molecule encodes a protein that selectively binds to immune serum isolated from an animal that is immune to infection by Dirofilaria immitis.