Patent ID: 6756394
Filing Date: 2004-06-29
Classification: A61P,C07C,C07D

Abstract:
A method for decreasing necrosis in a subject in a with a disease or condition selected from the group consisting of: Alzheimer's disease, Huntington's disease, cerebral ischemia, stroke, amyotropic lateral sclerosis, multiple sclerosis, Lewy body disease, Menke's disease, Wilson disease, Creutzfeldt-Jakob disease, and Fahr disease, said method comprising treating a cell with a chemical compound of the formula: whereineach R1 is independently selected from the group consisting of hydrogen methyl, carboxy, hydroxyl, methyl, amino, and nitro; R2 is selected from the group consisting of hydrogen, alkyl, and acyl; R3 is selected from the group consisting of alkyl, acyl, halogen, hydrogen, and hydroxyl; R4 is selected from the group consisting of methyl, hydroxyl, carboxyl, and linear and branching alkyl groups; and each of the bonds (a), (b), and (c) independently is either a double or single bond, provided, however, that bond (a) and bond (b) are not both double bonds.