Patent ID: 6743811
Filing Date: 2004-06-01
Classification: A61P,C07D

Abstract:
A compound of Formula 4: wherein:R7 is aryl; R8, is NR, S, C(&boxH;O)NR, NRC(&boxH;O), C(&boxH;O)O, OC(&boxH;O), OC(&boxH;O)NR, C(&boxH;S)NR, NRC(&boxH;S), OC(&boxH;S)NR, NRC(&boxH;S)O, or NRC(&boxH;S)NRâ€², wherein R and Râ€² are independently H, alkyl, heteroalkyl, aryl or heteroaryl; and R9 is hydrogen, ORâ€³, SRâ€³, NRâ€³Râ€²â€³, alkyl, aryl, or heteroaryl, wherein Râ€³ and Râ€²â€³ each are independently H, alkyl, heteralkyl, aryl or heteroaryl; and R10 and R11 are independently hydrogen, alkyl, heteroalkyl, aryl or hetoroaryl, with the proviso that when R6 is NR, C(&boxH;O)NR, or C(&boxH;O)O, and R is hydrogen or alkyl, then R9 is different from hydrogen and alkyl; when R8 is S, then R9 is different from hydrogen; and, when R9 is NRC(&boxH;O), then R9 is different from alkyl.