Patent ID: 6251589
Filing Date: 2001-06-26
Classification: C12Q

Abstract:
A method for diagnosing spinocerebellar ataxia type 2 in a human nucleic acid sample comprising the steps of:amplifying said nucleic acid sample with a first primer and a second primer by polymerase chain reaction, wherein said first primer hybridizes to a region of SEQ ID NO:1 and said second primer hybridizes to a region of SEQ ID NO:3;obtaining an amplification product of said nucleic acid sample by said polymerase chain reaction; andmeasuring a number of CAG repeats in said amplification product,wherein a number of 35 or more CAG repeats in said nucleic acid sample is indicative of said spinocerebellar ataxia type 2 and a number of 15-24 CAG repeats in said nucleic acid sample would be negative for spinocerebellar ataxia type 2.