Patent ID: 6800778
Filing Date: 2004-10-05
Classification: A61K,A61P,C07B,C07D,C07F

Abstract:
A compound represented by the formula (IIa): wherein ring A is a benzene ring optionally having 1 to 5 substituents selected from the group consisting of(1) C1-6 alkyl group which may have a substituent selected from the group consisting of (i) halogen atom, (ii) C1-7 alkoxy group, (iii) C1-7 alkylthio group, (iv) hydroxy group, (v) acetylamino, (vi) benzoylamino, (vii) methanesulfonylamino and (viii) benzenesulfonylamino, (2) hydroxy group, (3) linear or branched C1-6 alkoxy group, (4) C1-4 alkanoyloxy group, (5) carbamoyloxy group which may have 1 or 2 C1-4 alkyl groups, (6) thiol group, (7) C1-4 alkyithio group, (8) C1-4 alkanoylthio group, (9) nitro group, (10) C1-6 alkanoyl group, (11) C1-4 alkylsulfonyl group, (12) benzenesulfonyl, (13) p-toluenesulfonyl, (14) carbamoyl group, (15) mono- or di-C1-10 alkylcarbamoyl group, (16) mono- or di-C6-14 arylcarbamoyl group, (17) mono- or di-C7-16 aralkylcarbamoyl group, (18) sulfamoyl group, (19) mono- or di-C1-10 alkylsulfamoyl group, (20) mono- or di-C6-14 arylsulfamoyl group, (21) mono- or di-C7-16 aralkylsulfamoyl group, (22) C1-4 alkoxy-carbonyl group, (23) halogen atom and (24) methylenedioxy group which may have a substituent selected from the group consisting of (i) halogen, (ii) nitro group, (iii) hydroxy group and (iv) amino group; Alk is a C2-4 alkylene optionally having substituents selected from the group consisting of(1) C1-4 alkyl group, (2) C1-4 alkoxy group, (3) hydroxy group, (4) amino group, (5) nitro group and (6) halogen group; and * shows the position of an asymmetric carbon,or a salt thereof.