Patent ID: 7994304
Filing Date: 2011-08-09
Classification: C07H

Abstract:
1. A nucleoside triphosphate analog comprising a chemical structure within the following formula: wherein: NTP is a nucleoside triphosphate or analog thereof capable of incorporating onto the 3′ end of a polynucleotide strand hybridized to a template presenting the complement of said NTP; R1 is an alkyl, alkenyl, alkynyl amide, or alkyl amide; R2 is a cleavable bond or group; R3 is an alkyl, alkenyl, alkyl amide, alkynyl amide, aryl, ether, or ester; R4 is selected from the group consisting of: OH, phosphoryl , sulfate, NH Y, at each occurrence, independently is O or S; Z represents H or a halogen; R5 and R6 are independently selected from the group consisting of: H, OH, phosphoryl, P X is selected from the group consisting of: O, S, or CH