Patent ID: 8632982
Filing Date: 2014-01-21
Classification: C12Q,G01N

Abstract:
1. A kit for use in performing a method for detecting liver damage which kit comprises a panel of at least four protein-binding members, wherein each member is specifically reactive with one protein selected from the group consisting of asialoglycoprotein receptor 2 (ASGR2), 10-formyltetrahydro dehydrogenase (ALDH1L1), formiminotransferase cyclodeaminase (FTCD), catechol-O-methyltransferase (COMT), dihydropyrimidinase (DPYS), carbamoyl phosphate synthase (CPS1), fructose-1,6-bisphosphatase 1 (FBP1), fumarylacetoacetate hydrolase (FAH), glycine-N-methyltransferase (GNMT), 3-hydroxy-3-methylglutaryl-coenzyme A synthase 2 (HMGCS2), methionine adenosyltransferase 1 (MAT1A), plasminogen (PLG) and retinal binding protein 4 (RBP4); wherein each protein binding member binds a different protein of said group; and reagents for detecting a complex formed between said member and said protein.