Patent ID: 8153647
Filing Date: 2012-04-10
Classification: A61P,C07C,C07D

Abstract:
1. A compound corresponding to the following formula (I): wherein: A represents a phenyl group; Q represents an oxygen atom or a —CH X, Y and Z represent carbon or nitrogen atoms, provided that: R1 and R2, identical or different, are chosen from among the list of atoms and groups consisting of: hydrogen, halogen, hydroxyl, cyano, oxo, —CF R3 represents a linear (C1-C10)alkyl group which is optionally substituted by one to three groups, identical or different, chosen from among the list of atoms and groups consisting of halogen atoms and (C1-C4)alkoxy, R4 represents a hydrogen or halogen atom or a hydroxyl, cyano, (C1-C6)alkyl or (C1-C6)alkoxy group, R5 and R6 represent, independently one from the other, a hydrogen or halogen atom or a (C1-C5)alkyl group, or R5 and R6 together form, with the carbon atom to which they are attached, a (C3-C6)cycloalkyl group, R7 and R8 represent, independently one from the other, a hydrogen atom or a (C1-C5)alkyl group, or R7 and R8 together form, with the carbon atom to which they are attached, a (C3-C6)cycloalkyl group, R9 and R10 represent, independently one from the other, a hydrogen atom or a hydroxyl, —CO—(C1-C6)alkyl or —COO—(C1-C6)alkyl group, or R9 and R10 together form a linear (C2-C3)alkylene chain, thereby forming a 5 or 6-membered ring with the nitrogen atoms to which they are attached, said alkylene chain being optionally substituted by one to three groups chosen from among the list of atoms and groups consisting of: (C1-C4)alkyl, (C3-C6)cycloalkyl groups in the spiro position, oxo, hydroxyl and amino, and R11 represents a hydrogen atom or a (C1-C8)alkyl or (C3-C6)cycloalkyl group, which is optionally substituted by one to three groups chosen from among list of atoms and groups consisting of: halogen atoms, hydroxyl, cyano, (C1-C6)alkoxy, —NR18R19, —COOR18, —CO—NR18R19 and pyridinyl; in the form of a free base or of an addition salt with an acid or a base.