Patent ID: 8759018
Filing Date: 2014-06-24
Classification: C12Q,G01N,Y10T

Abstract:
1. A method for selecting therapy for a patient diagnosed with disseminated intravascular coagulation (DIC), said method comprising: collecting a sample of bodily fluid from the patient diagnosed with DIC; analyzing the sample for enzyme activity (Aact) of a von Willebrand factor-cleaving protease (ADAMTS13) and the amount (Vag) of von Willebrand factor (vWF); calculating a ratio of the amount of vWF to the enzyme activity of ADAMTS13 (Vag/Aact); and selecting a therapy for thrombotic thrombocytopenic purpura (TTP) when the calculated ratio (Vag/Aact) value in the DIC patient is half or more of the ratio (Vag/Aact) in known TTP patients.