Patent ID: 6642041
Filing Date: 2003-11-04
Classification: C07K,C12N

Abstract:
An isolated nucleic acid molecule comprising a polynucleotide sequence selected from the group consisting of:(a) an isolated polynucleotide encoding a polypeptide corresponding to amino acids 1 to 414 of SEQ ID NO: 2 including the start codon; (b) an isolated polynucleotide encoding a polypeptide corresponding to amino acids 2 to 414 of SEQ ID NO: 2 minus the start codon; (c) an isolated polynucleotide encoding a polypeptide corresponding to amino acids 148 to 414 of SEQ ID NO: 2 including the start codon; (d) an isolated polynucleotide encoding a polypeptide corresponding to amino acids 149 to 414 of SEQ ID NO: 2 minus the start codon; (e) an isolated polynucleotide encoding a polypeptide corresponding to amino acids 176 to 414 of SEQ ID NO: 2; (f) an isolated polynucleotide encoding the MP-1 polypeptide as encoded by the cDNA clone contained in ATCC Deposit No: PTA-2766; (g) an isolated polynucleotide encoding at least 274 contiguous amino acids of SEQ ID NO: 2 having metalloproteinase activity; and (h) an isolated polynucleotide which represents the complimentary sequence (antisense) of (a), (b), (c), (d), (e), (f) or (g) wherein (a), (b), (c), (d), (e), (f) or (g) have metalloproteinase activity.