Patent ID: 6380429
Filing Date: 2002-04-30
Classification: C07C,C07D,C40B

Abstract:
A process for the oxidation of sulfonamide of the structure I where R1 and R2 are independently selected from the group consisting of hydrogen and organic radicals not possessing a hydrogen atom in the position beta to the nitrogen of the sulfonamide group, and R3 is an organic radical selected from the group consisting of alkyl, substituted alkyl, aryl and substituted aryl groups, and optionally, R1 and R2 can form a ring, to sulfonyl imines of the structure II, wherein R1, R2, and R3 are described above, said process comprising:(a) optionally, contacting a sulfonamide of the structure I with a suitable solvent or liquid; (b) contacting the sulfonamide of the structure I with chromium (IV) dioxide under oxidizing conditions whereby a sulfonyl imine product is produced; and (c) optionally, isolating the sulfonyl imine product.