Patent ID: 6060485
Filing Date: 2000-05-09
Classification: C07D

Abstract:
An arylacetic amide derivative represented by the following formula (1): ##STR154## wherein R.sup.1 represents a phenyl, naphthyl, thienyl, furanyl, imidazolyl, pyridyl, pyrazyl, pyrimidyl, pyridazyl, quinolyl, isoquinolyl, quinazolyl, quinoxalyl or cinnolyl group which may be substituted with one to five substituents selected from the group consisting of a halogen atom and halogeno C.sub.1-6 alkyl), C.sub.1-6 alkyl, C.sub.1-6 alkoxy, amino, benzyloxy, cyano, benzoyl, C.sub.1-6 alkanoyl, carbamoyl, carboxy, carboxy (C.sub.1-6 alkyl), C.sub.1-6 alkanoyloxy, nitro and sulfonamide groups, R.sup.2 and R.sup.3 each independently represents a C.sub.1-8 linear, branched, cyclic or cyclic-linear alkyl, C.sub.2-6 alkenyl, phenyl (C.sub.1-6 alkyl), nitrogen-containing saturated heterocyclic or heteroaromatic-(C.sub.1-6 alkyl) group which may be substituted with a hydroxy group, amino group or substituted amino group, R.sup.4 represents a phenyl, naphthyl, thienyl, furanyl, imidazolyl, pyridyl, pyrazyl, pyrimidyl, pyridazyl, quinolyl, isoquinolyl, quinazolyl, quinoxalyl, cinnolyl, phenyl (C.sub.1-6 alkyl), or heteroaromatic-(C.sub.1-6 alkyl) group which may be substituted with one to five substituents selected from the group consisting of a halogen atom and halogeno (C.sub.1-6 alkyl), C.sub.1-6 alkyl, C.sub.1-6 alkoxy, amino, benzyloxy, cyano, benzoyl, C.sub.1-6 alkanoyl, carbamoyl, carboxy, carboxy (C.sub.1-6 alkyl), C.sub.1-6 alkanoyloxy, nitro and sulfonamide groups, and n stands for 0 or 1; or salt thereof.