Patent ID: 6255339
Filing Date: 2001-07-03
Classification: C07D

Abstract:
A compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof: ##STR58##whereinR.sup.1 representsa hydroxyl group,optionally substituted C.sub.1 -C.sub.10 alkyloxy,optionally substituted C.sub.2 -C.sub.10 alkenyloxy,optionally substituted C.sub.2 -C.sub.10 alkynyloxy,C.sub.3 -C.sub.6 cycloalkyloxy,C.sub.2 -C.sub.12 alkoxyalkyloxy,five- or six-membered cycloalkyloxy containing one oxygen atom,optionally substituted C.sub.7 -C.sub.15 aralkyloxy,optionally substituted C.sub.2 -C.sub.11 alkylcarbonyloxy,optionally substituted C.sub.3 -C.sub.11 alkenylcarbonyloxy,optionally substituted C.sub.3 -C.sub.11 alkynylcarbonyloxy,C.sub.4 -C.sub.15 cycloalkylcarbonyloxy,C.sub.2 -C.sub.11 alkoxycarbonyloxy,C.sub.7 -C.sub.15 aryloxy carbonyloxy,optionally substituted C.sub.8 -C.sub.15 aralkylcarbonyloxy,optionally substituted C.sub.7 -C.sub.15 aromatic acyloxy,optionally substituted C.sub.3 -C.sub.15 heteroaromatic acyloxy having at least one hetero atom selected from the group consisting of nitrogen, oxygen, and sulfur atoms,optionally substituted C.sub.4 -C.sub.12 saturated heterocyclic carbonyloxy having at least one hetero atom selected from the group consisting of nitrogen, oxygen, and sulfur atoms,C.sub.1 -C.sub.6 alkylsulfonyloxy,optionally substituted C.sub.6 -C.sub.12 aromatic sulfonyloxy,C.sub.2 -C.sub.7 alkylcarbamoyloxy,optionally substituted C.sub.7 -C.sub.12 aromatic carbamoyloxy,optionally substituted C.sub.2 -C.sub.11 alkylcarbonylamino,optionally substituted C.sub.7 -C.sub.15 aromatic acylamino,a hydrogen atom,optionally substituted C.sub.1 -C.sub.10 alkyl,optionally substituted C.sub.2 -C.sub.10 alkenyl, oroptionally substituted C.sub.2 -C.sub.10 alkynyl;R.sup.2 representsa hydroxyl group,optionally substituted C.sub.1 -C.sub.10 alkyloxy,optionally substituted C.sub.2 -C.sub.10 alkenyloxy,optionally substituted C.sub.2 -C.sub.10 alkynyloxy,C.sub.3 -C.sub.6 cycloalkyloxy,C.sub.2 -C.sub.12 alkoxyalkyloxy,five- or six-membered cycloalkyloxy containing one oxygen atom,optionally substituted C.sub.7 -C.sub.15 aralkyloxy,optionally substituted C.sub.2 -C.sub.11 alkylcarbonyloxy,optionally substituted C.sub.3 -C.sub.11 alkenylcarbonyloxy,optionally substituted C.sub.3 -C.sub.11 alkynylcarbonyloxy,C.sub.4 -C.sub.15 cycloalkylcarbonyloxy,C.sub.2 -C.sub.11 alkoxycarbonyloxy,C.sub.7 -C.sub.15 aryloxy carbonyloxy,optionally substituted C.sub.8 -C.sub.15 aralkylcarbonyloxy,optionally substituted C.sub.7 -C.sub.15 aromatic acyloxy,optionally substituted C.sub.3 -C.sub.15 heteroaromatic acyloxy having at least one hetero atom selected from the group consisting of nitrogen, oxygen, and sulfur atoms,optionally substituted C.sub.4 -C.sub.12 saturated heterocyclic carbonyloxy having at least one hetero atom selected from the group consisting of nitrogen, oxygen, and sulfur atoms,C.sub.l -C.sub.6 alkylsulfonyloxy,optionally substituted C.sub.6 -C.sub.12 aromatic sulfonyloxy,C.sub.2 -C.sub.7 alkylcarbamoyloxy,optionally substituted C.sub.7 -C.sub.12 aromatic carbamoyloxy,optionally substituted C.sub.2 -C.sub.11 alkylcarbonylamino,optionally substituted C.sub.7 -C.sub.15 aromatic acylamino;R.sup.3 representsa hydrogen atomoptionally substituted C.sub.l -C.sub.10 alkyl, oroptionally substituted C.sub.2 -C.sub.10 alkenyl;R.sup.4 representsa hydrogen atomoptionally substituted C.sub.1 -C.sub.10 alkyl, oroptionally substituted C.sub.2 -C.sub.10 alkenyl; andR.sup.5 representsa hydrogen atomoptionally substituted C.sub.1 -C.sub.10 alkyl, oroptionally substituted C.sub.2 -C.sub.10 alkenyl,provided that a compound wherein both R.sup.1 and R.sup.2 represent a hydroxyl group, R.sup.3 and R.sup.5 represent a hydrogen atom, and R.sup.4 represents methyl, a compound wherein R.sup.1 represents methylcarbonyloxy, and R.sup.2 represents a hydroxyl group, R.sup.3 and R.sup.5 represent a hydrogen atom, and R.sup.4 represents methyl, a compound wherein R.sup.1 represents a hydroxyl group, R.sup.2 represents methylcarbonyloxy, R.sup.3 and R.sup.5 represent a hydrogen, and R.sup.4 represents methyl, and a compound wherein R.sup.1 represents a hydrogen atom, R.sup.2 represents C.sub.1-15 alkyloxy or C.sub.2-5 alkylcarbonvloxy, R.sup.3 represents a hydrogen atom, R.sup.4 represents methyl, and R.sup.5 represents a hydrogen atom, are excluded.