Patent ID: 6515100
Filing Date: 2003-02-04
Classification: A61K,C08G

Abstract:
A polymer derivative comprising a water-soluble and non-peptidic polymer backbone having at least one terminus bonded to the structure:â€”Wâ€”T wherein W is a hydrolytically unstable ester linkage selected from the group consisting of â€”O2Câ€”(CH2)nâ€”Oâ€”, â€”Oâ€”(CH2)nâ€”CO2â€”(CH2)mâ€”, â€”Oâ€”(CH2)nâ€”CO2â€”(CH2)mâ€”Oâ€”, â€”(CH2)nâ€”OPO3â€”(CH2)mâ€”, and â€”Oâ€”(CH2)nâ€”CO2â€”(CHR)mâ€”, wherein each R is H or alkyl, provided at least one R is alkyl, n is from about 1 to about 5, and m is about 1 to about 5, and T is a reactive group.