Patent ID: 6214842
Filing Date: 2001-04-10
Classification: C07D

Abstract:
A compound of formula I having the structure ##STR13##wherein:R is hydrogen or alkyl of 1-6 carbon atoms;A is ##STR14##R.sup.1, R.sup.2, R.sup.3 are each, independently, hydrogen, alkoxy of 1-6 carbon atoms, thioalkyl of 1-6 carbon atoms, trifluoromethyl, ##STR15##R.sup.4 is hydrogen, alkyl of 1-6 carbon atoms, halogen, or alkoxy of 1-6 carbon atoms;R.sup.5 is phenyl, naphthyl, thienyl, furyl, wherein R.sup.5 may be optionally mono-, di-, or tri-substituted with a sustituent selected from the group consisting of alkyl of 1-6 carbon atoms, alkoxy of 1-6 carbon atoms, trifluoromethyl, halogen, alkoxycarbonyl of 2-7 carbon atoms, alkylamino of 1-6 carbon atoms, and dialkylamino in which each of the alkyl groups is of 1-6 carbon atoms, nitro, cyano, --CO.sub.2 H, alkylcarbonyloxy of 2-7 carbon atoms, and alkylcarbonyl of 2-7 carbon atoms;m=1-4;n=1-4; andX=O, S,or a pharmaceutically acceptable salt thereof.