Patent ID: 8541466
Filing Date: 2013-09-24
Classification: A61K,A61P,A61Q

Abstract:
1. A method of treating hair loss, wherein the method comprises topically applying to mammalian skin a safe and effective amount of a composition comprising: A) an active ingredient selected from the group consisting of a prostaglandin F analog having a structure selected from the group consisting of pharmaceutically acceptable salts of the structures above; biohydrolyzable amides, esters, and imides of the structures above; optical isomers, diastereomers, and enantiomers of the structures above; and combinations thereof; wherein R R R R X is selected from the group consisting of —C≡C—, a covalent bond, —CH═C═CH—, —CH═CH—, —CH═N—, —C(O)—, —C(O)Y—, —(CH Y is selected from the group consisting of a sulfur atom, an oxygen atom, and NH; and Z is selected from the group consisting of a carbocyclic group, a heterocyclic group, an aromatic group, a heteroaromatic group, a substituted carbocyclic group, a substituted heterocyclic group, a substituted aromatic group, and a substituted heteroaromatic group, with the proviso that when the bond at the C2-C3 position is a double bond, the bond at C5-C6 position is a double bond, R