Patent ID: 6312931
Filing Date: 2001-11-06
Classification: A61L,C12N

Abstract:
A method of protecting a biomolecule from substantial degradation while reducing the content of a pathogen or chemical toxin contained by of a biologically derived composition, which method comprises:providing a biologically derived composition containing a pathogen or chemical toxin and at least one biologically active biomolecule;adding albumin to said composition to create a supplemented composition;subjecting said supplemented composition to polychromatic pulsed light to degrade said pathogen or toxin, wherein the polychromatic pulsed light includes at least one high-intensity, short duration pulse of incoherent polychromatic light in a broad spectrum wherein the light intensity is at least about 0.01 J/cm.sup.2, the pulse duration is 10 ns to 100 ms and the light wavelengths are between about 170 nm and about 2600 nm,the content of said albumin in said supplemented composition being such that said subjecting reduces the content of said pathogen or chemical toxin by at least a factor of 10 without degrading the biological activity of said biomolecule to an unacceptable level, andrecovering said biomolecule in a biologically active state.