Patent ID: 6211340
Filing Date: 2001-04-03
Classification: C07K

Abstract:
A monoclonal antibody which binds specifically to the 35 kDa dystrophin-associated .delta.-sarcoglycan protein, the monoclonal antibody being produced by:a) providing an immunogenic peptide comprising the amino acids VLGAEGTVFPK (SEQ ID NO:3);b) formulating the peptide in a pharmaceutically acceptable carrier;c) administering the formulation of step b) to a mammal under conditions appropriate for the stimulation of an immune response; andd) isolating antibody producing cells from the mammal;e) fusing the antibody producing cells with immortalizing cells to produce a hybridoma cell line; andf) screening the resulting hybridoma cell line to identify cell lines secreting antibody having the desired specificity.