Patent ID: 6344569
Filing Date: 2002-02-05
Classification: C07C,C07D

Abstract:
A process for producing a 6-cyanomethyl-1,3-dioxane-4-acetic acid derivative of the general formula (3): wherein R1, R2 and R3 each independently represents a hydrogen atom, an alkyl group containing 1 to 12 carbon atoms, an aryl group containing 6 to 10 carbon atoms or an aralkyl group containing 7 to 12 carbon atoms, which comprises reacting the 3,5-dihydroxy-6-halohexanoic acid derivative of the general formula (1): wherein R1 is as defined above and X represents a halogen atom, with a cyanating agent to provide a 6-cyano-3,5-dihydroxyhexanoic acid derivative of the general formula (2): wherein R1 is as defined above,followed by an acetal formation reaction of the same with an acetal forming reagent in the presence of an acid catalyst.