Patent ID: 6825200
Filing Date: 2004-11-30
Classification: A61K,A61P,C07K

Abstract:
A compound of the formula (I): whereinR1 is benzofuranyl substituted by halogen, or styryl substituted by halogen, R2 is phenyl, pyridyl, thienyl or thiazolyl, each of which is optionally substituted by one or more substituents selected from the group consisting of lower alkyl, lower alkoxy, halogen and trihalo(lower)alkyl, or lower alkyl optionally substituted by one or more halogen atoms, R3 is hydrogen or lower alkoxy, R4 and R5 are the same or different and each is hydrogen, lower alkyl, hydroxy(C1-C6)alkyl, hydroxymethyl, 1-hydroxyethyl, 2-hydroxyethyl, 1-hydroxypropyl, 2-hydroxypropyl, 3-hydroxypropyl, 4-hydroxybutyl, 5-hydroxypentyl, 6-hydroxyhexyl, lower alkoxy(lower)alkyl, (C1-C6)alkoxy(C1-C6)alkyl, methoxymethyl, 1-methoxyethyl, 2-methoxyethyl, 1-methoxypropyl, 2-methoxypropyl, 3-methoxypropyl, ethoxymethyl, 2-ethoxyethyl, 3-ethoxypropyl or propoxymethyl, and R6 is hydrogen or lower alkyl, or a pharmaceutically acceptable salt thereof.