Patent ID: 7491768
Filing Date: 2009-02-17
Classification: C08K

Abstract:
1. A method for preparing an anti-microbial or anti-coagulating polymer resin comprising the step of mixing a polymer resin with at least one kind of pharmaceutically active material without using a solvent, wherein the pharmaceutically active material is an anti-microbial selected from the group consisting of grepafloxacin, sparfloxacin, clinafloxacin, enoxacin, lemefloxacin, norfloxacin, pipemidic acid, ciprofloxacin, temafloxacin, tosufloxacin, ketoconazole, itraconazole, econazole, isoconazole, fluconazole, miconazole, terbinafin, a salt thereof, and a mixture thereof, wherein the pharmaceutically active material is an anti-coagulant selected from a group consisting of warfarin, acetylsalicylic acid, ticlopidine, triflusal, clopidogrel, cilostazole, a salt thereof, and a mixture thereof, and wherein the method comprises the step of adding one or more kinds of additives selected from a group consisting of a dispersant, an anti-oxidant, and a heat stabilizer, wherein the polymer resin is selected from a group consisting of polyetherimide, polyethylene, polypropylene, polycarbonate, polyvinylchloride, polystyrene, epoxy resin, polytetrafluoroethylene, polyacetal, polyamide, polyurethane, ethylene-vinylacetate copolymer, polymethylmethacrylate, polyvinylalcohol, linear low density poly ethylene, low density polyethylene, high density polyethylene, acrylonitrile-butadiene-styrene, styrene-acrylonitrile, polyacrylonitrile, polybutadiene, polyacrylic acid, polyacrylimide, polysulfone, polyacetal, polyamide-imide, polytetrafluoroethylene, polyneoprene, polydimethylsiloxane, polymethylmethacrylate, polyetheretherketone, polyphenylenesulfide, polyvinylfluoride, polyvinylacetate, polyvinylidinefluoride, polyether sulfone, polycaprolactone and a copolymer thereof; a silicon resin; a natural rubber; a synthetic rubber; and a mixture thereof, wherein the dispersant is N,N'-ethylene bis stearamide, polyethylene wax, or a mixture thereof.