Patent ID: 7960571
Filing Date: 2011-06-14
Classification: C07B,C07C,C07F,C12C,Y02P

Abstract:
1. A silicon-based cross-coupling reagent, comprising: an organosilicon compound reacting with an organic compound having a halogen leaving group or a pseudo halogen leaving group in the presence of a palladium catalyst and a base to form a carbon-carbon bond between a carbon atom connected to the halogen leaving group or the pseudo halogen leaving group and a carbon atom connected to a silicon atom of the organosilicon compound in accordance with a cross-coupling reaction, wherein the silicon-based cross-coupling reagent has a structure represented by the following formula (1) where R the substituent being a hydrocarbon group, heterocyclic group, cyano group, formyl group, alkoxycarbonyl group, carboxyl group, phosphate group, sulfo group, hydroxy group, sulfonyl group, halogen, acyl group, alkoxy group, amino group, nitro group, imino group, trialkylsiloxy group, or hydroxyl alkyl group, and R