Patent ID: 6180718
Filing Date: 2001-01-30
Classification: C07B,C07C,C07D,C08F,C40B

Abstract:
A process for preparing pharmaceuticals or agrochemicals comprising:a) An aryllithium or heteroaryllithium reagent is first reacted with a substituted or unsubstituted dichlorosilane forming a silicon-carbon bond;b) The resulting aryl-chlorosilane is reacted in one or more synthetic steps with a solid-supported hydroxyl group to form a silicon-oxygen bond (silyl ether) which thereby links the aromatic or heteroaromatic synthon to the solid support;c) The solid-supported aromatic or heteroaromatic synthon is reacted, in one or more synthetic steps, to form a solid-supported molecules which, when detached from the support, afford pharmaceuticals or agrochemicals.