Patent ID: 8507003
Filing Date: 2013-08-13
Classification: A61K

Abstract:
1. A microcapsule providing prolonged release in vivo of at least one active principle (AP), wherein the microcapsule has a particle size of between 50 and 1000 microns; wherein the microcapsule comprises a non-deformable core comprising at least one AP in an amount of 50 to 80% by dry weight; wherein the non-deformable core is covered with at least one film coating controlling the prolonged release of the AP in vivo; and wherein the microcapsule comprises at least one outer overcoating envelope the overcoating envelope consisting of: (1) magnesium stearate and (2) at least 10% by weight of one deformable organic constituent having a melting point of between 40° C. and 120° C., the deformable organic constituent consisting of polyethylene glycol having a molecular weight of between 6,000 and 20,000 D.