Patent ID: 6566076
Filing Date: 2003-05-20
Classification: C07K,G01N

Abstract:
A method for detecting lung injury in a human subject, the method comprising the steps of:contacting a specific anti-human type II alveolar cell monoclonal antibody with a test sample from a subject suspected of having lung injury, wherein the sample is suspected of comprising a human type II alveolar cell-specific polypeptide, wherein the human type II alveolar cell-specific polypeptide is HTII280; and detecting binding of the anti-human type II alveolar cell monoclonal antibody to the human type II alveolar cell-specific polypeptide in the sample; wherein detection of binding of the anti-human type II alveolar cell monoclonal antibody to human type II alveolar cell-specific polypeptide in the sample at a level substantially elevated relative to a level in a normal subject is indicative of lung injury in the subject.