Patent ID: 7713745
Filing Date: 2010-05-11
Classification: A61B,G01N

Abstract:
1. A method for non-covalently attaching a macromolecular indicator to a support comprising: (a) providing a support having an outer surface which comprises at least one polymer, wherein said support is a sensor body or an optical waveguide; (b) changing the integrity of the polymer to provide loosened polymer chains that form at least one interlacing area on the surface; (c) providing at least one macromolecular indicator or monomers thereof; (d) causing the macromolecular indicator to interlace with said at least one interlacing area on the surface, or causing the sequential polymerization of said monomers to form polymerization products which interlace with said at least one interlacing area on the surface; and (e) causing the loosened polymer chains to tighten to produce surface immobilized indicator molecules.