Patent ID: 6670400
Filing Date: 2003-12-30
Classification: A61P,C07C,C07D

Abstract:
A compound selected from the group consisting of a compound of the formula wherein Ar is unsubstituted or substituted phenyl with at least one member selected from the group consisting of halogen, alkyl and alkoxy of 1 to 6 carbon atoms, â€”CN, â€”NO2, â€”OH, and â€”SR12, R1, R2, R3, R4, R5, R6, R7 and R8 are independently hydrogen or lower alkyl and R9, R10, R11 and R12 are independently lower alkyl and R is selected from the group consisting of alkyl, alkenyl and alkynyl of up to 10 carbon atoms, phenyl unsubstituted or substituted with at least one member of the group consisting of alkyl and alkoxy of 1 to 6 carbon atoms, halogen, â€”OH, â€”NO2, â€”NH2 and acylamino of an organic carboxylic acid and cycloalkyl, alkylcycloalkyl and cycloalkylalkyl of up to 7 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts.