Patent ID: 6518058
Filing Date: 2003-02-11
Classification: C12M,C12P

Abstract:
A device for synthesis of polypeptides in a cell-free translation system containing at least one reactor module including a reactor volume having an inlet and an outlet for linking liquid circuits and including at least two porous barriers, a system for supply of different fractions of the feed solution and expendable high molecular weight components, consisting of at least one pump, liquid circuits, compartments for accumulation and storage of products or feed solution, wherein the reactor comprises at least one reactor volume, whose external surface contacts the external surface of the first and second porous barriers, the internal surface of the second porous barrier is connected to the zone of the inlet or outlet of low molecular weight flows, the internal side of the first porous barrier is connected to the zone of the inlet and outlet of low molecular weight flows and flows containing high molecular weight components with the target polypeptide.