Patent ID: 7452860
Filing Date: 2008-11-18
Classification: A61K,A61P

Abstract:
1. A formulation comprising per milliliter: (a) 1.4 to 35 mg of Lys(B3), Glu(B29) human insulin; (b) 10 to 100 μg of polysorbate 20; (c) 1 to 5 mg m-cresol; (d) 5 to 7 mg of tromethamine; (e) 1 to 8 mg NaCl; and (f) water; wherein the formulation is free from zinc or contains less than 0.2% by weight of zinc based on the insulin content of the formulation; and wherein the pH of the formulation is 7.3+/−0.2.