Patent ID: 7862835
Filing Date: 2011-01-04
Classification: A61L

Abstract:
1. A method of manufacturing a coated medical device having a coating containing fissures, the method comprising: providing a medical device; preparing a mixture comprising a solvent, a drug, and a polymer; dispersing solid particle additives in the mixture to form a suspension comprising dispersed solid particle additives; applying the suspension on the medical device to form a coating containing fissures on the medical device; and evaporating the solvent to shrink the coating and cause the mixture to separate from the solid particle additives, thereby creating the fissures in the coating on the medical device, wherein the solid particle additives remain in the coating during use of the medical device in the body, wherein the solid particle additives and the drug are not both bone morphogenic proteins, and wherein the solid particle additives are a separate component from the drug.