Patent ID: 7884107
Filing Date: 2011-02-08
Classification: A61P,C07D

Abstract:
1. A compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein: R (a) heterocyclyl selected from the group consisting of piperazinyl, piperidinyl, and pyrrodinyl; each of which can be unsubstituted or independently substituted with at least one moiety, which may be the same or different, selected from the group Z; (b) heterocyclenyl, that is 1,2,3,6-tetrahydropyridinyl which can be unsubstituted or independently substituted with at least one moiety, which may be the same or different, selected from the group Z; wherein each of said heterocyclyl, or heterocyclenyl is attached by one of its heteroatoms to the carbonyl in Formula I; (c) or (d) selected from the group consisting of: wherein each Z, which can be the same or different, is independently selected from the group consisting of H, —OR further wherein, R R further wherein, in any —NR A is O; m is 0-2; R aryl, or heteroaryl, wherein X is selected from the group consisting of aryl, heteroaryl, arylalkyl, alkyl, and trihaloalkyl; further wherein, each of said X, aryl, and heteroaryl can be unsubstituted or substituted with one or more moieties, which can be the same or different, each moiety being independently selected from the group consisting of trihaloalkyl, halogen, CN, hydroxyl, alkoxy, aryloxy, alkyl, and cycloalkyl; R or wherein R R R provided that the following compounds, which are identified as Group A Compounds herein, are excluded from Formula I: