Patent ID: 6982329
Filing Date: 2006-01-03
Classification: C07J,Y02P

Abstract:
1. A method comprising: a) providing a compound of the formula: wherein: each of C1, C2, C4, C11, C12, C15 and C16 is independently substituted with i) one of: ═O, ═C(R ii) two of the following, which are independently selected: —X, —R C3 is substituted with hydrogen or -ZR each of C8, C9 and C14 is independently substituted with one of —X, —R C17 is substituted with two —OR R R R X represents fluoride, chloride, bromide and iodide; and Z is selected from O, S and NR b) contacting the compound with reagents comprising copper iodide and t-butyl hydroperoxide to provide a mixture; and c) maintaining the mixture of step b) under oxidizing conditions to convert to compound to a product having a carbon skeleton and an α,β-unsaturated ketone moiety as present in formula (4)