Patent ID: 6881208
Filing Date: 2005-04-19
Classification: A61N,A61P

Abstract:
1. A method for delivering an active agent through a body surface by electrotransport comprising the steps of: a) providing an electrotransport delivery device having a silver anodic donor electrode, a cathodic counter electrode, and a donor reservoir containing a loading amount of the analgesic drug in electrical contact with the donor electrode, wherein the donor reservoir is substantially free of sources of halide other than the selected analgesic drug halide salt, the device adapted to deliver a predetermined maximum total amount of analgesic drug over a period of time, the loading amount being at loan about two times the predetermined maximum total amount to prevent transient epidermal discoloration; and b) delivering only up to the maximum total amount of the analgesic drug; wherein the analgesic drug is selected from the group consisting of fentanyl halide salts and sufentanil halide salts thereby avoiding transient epidermal discoloration.