Patent ID: 6570037
Filing Date: 2003-05-27
Classification: A61P,C07C

Abstract:
A compound of formula (I): or a salt thereof, or a solvate thereof, characterised in that:Ar represents substituted or unsubstituted aryl, wherein the optional substituents are selected from alkyl, hydroxy or alkoxy or, if attached to adjacent carbon atoms any two substituents together with the carbon atoms to which they are attached may form a fused heterocyclic ring of five to six atoms wherein one, two or three of the said atoms are oxygen or nitrogen; A represents a C1-4 n-alkylene group wherein each carbon is optionally substituted by 1 or 2 C1-6 alkyl groups; R1 represents hydrogen, alkyl, alkenyl or cycloalkyl; one or two of of the group of R2, R3 and R4 represents nitro the remaining members of the group of R2, R3 and R4 represent hydrogen; X represents a â€”COâ€”NHâ€” moiety; and Z represents C2-4 n-alkylene group wherein each carbon is optionally substituted by 1 or 2 C1-6 alkyl groups.