Patent ID: 8178539
Filing Date: 2012-05-15
Classification: A61P,C07D

Abstract:
1. A compound of the formula: wherein: R R R X is alkylene optionally interrupted by one or more —O— groups, and optionally substituted by a hydroxy or methoxy group; X′ is selected from the group consisting of alkylene, arylene, heteroarylene, and heterocyclylene wherein the alkylene group can be optionally interrupted or terminated by arylene, heteroarylene or heterocyclylene and optionally interrupted by one or more —O— groups; Y is selected from the group consisting of: R R R R R R R A is selected from the group consisting of —CH A′ is selected from the group consisting of —O—, —S(O) Q is selected from the group consisting of a bond, —C(R V is selected from the group consisting of —C(R W is selected from the group consisting of a bond, —C(O)—, and —S(O) a and b are independently integers from 1 to 6 with the proviso that a+b is ≦7; with the proviso that X can also be a bond when: wherein V is —C(R 6 )— or or a pharmaceutically acceptable salt thereof.