Patent ID: 6506770
Filing Date: 2003-01-14
Classification: A61P,C04B,C07D

Abstract:
A compound of formula I,Vâ€”CR1R2â€”Arâ€”CR3R4â€”N(R5)â€”(CR6R7)xâ€”R8â€ƒâ€ƒ(I) whereinV is an optionally substituted 4,7,10,17-tetraazabicyclo[13.3.1]heptadeca-1(17),13,15-trienyl system; R1 to R7 may be the same or different and are independently selected from hydrogen or straight, branched or cyclic C1-6 alkyl; R8 is pyridyl, pyrimidinyl, pyrazinyl, imidazolyl, thiophene-yl, thiophenyl, aminobenzyl, piperidinyl, piperazinyl or mercaptan; Ar is a phenylene ring optionally substituted at single or multiple positions with alkyl, aryl, amino, alkoxy, hydroxy, halogen, carboxyl and/or carboxamido; and x is 1 or 2; and the acid addition salts and metal complexes thereof.