Patent ID: 6930120
Filing Date: 2005-08-16
Classification: A61P,C07D

Abstract:
1. A compound represented by the following structural formula: or a pharmaceutically acceptable salt thereof wherein: (a) R1 is an unsubstituted or substituted thiophenyl, or thiophenyl-C1-C4 alkyl; wherein one or more substituents for thiophenyl or thiophenyl-C1-C4 are selected from the group consisting of: halo, carboxyl, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkyl, C1-C4 haloalkoxy, nitro, cyano, CHO, hydroxyl, C1-C4 alkanoic acid and —C(O)NR13R13; and wherein each R13 is independently H or a C1-C4 alkyl, (b) R2 is H, C1-C4 alkyl, C1-C4 haloalkyl or phenyl; (c) n is 2, 3, or 4; (d) W is O; (e) Y is an unsubstituted or substituted phenylene; wherein one or more substituents is selected from the group consisting of H, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkyl and C1-C4 haloalkoxy; (f) R3 is a C1-C4 alkyl or C1-C4 haloalkyl; (g) R4 is a substituted or unsubstituted phenyl, wherein one or more substituents are selected from the group consisting of: halo, carboxyl, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkyl, C1-C4 haloalkoxy, nitro, cyano, CHO, hydroxyl, C1-C4 alkanoic acid and —C(O)NR13R13; and wherein each R13 is independently H or a C1-C4 alkyl; and (h) R5 is H, C1-C4 alkyl, or aminoalkyl.