Patent ID: 6342587
Filing Date: 2002-01-29
Classification: A61K,C07K

Abstract:
A substantially pure immunoglobulin molecule which binds specifically to A33 antigen, comprising six CDRs, the amino acid sequences of which are selected from the group consisting of:(i) SEQ ID NO.: 68 or SEQ ID NO.: 69 (VLCDR1); (ii) SEQ ID NO.: 70 or SEQ ID NO.: 71 (VLCDR2); (iii) SEQ ID NO.: 72 or SEQ ID NO.: 73 (VLCDR3); (iv) SEQ ID NO.: 74 or SEQ ID NO.: 75 (VHCDR1); (v) SEQ ID NO.: 76, SEQ ID NO.: 77 or SEQ ID NO.: 78 (VHCDR2); and (vi) SEQ ID NO.: 79 or SEQ ID NO.: 80 (VHCDR3), wherein (i), (ii), (iii), (iv), (v), and (vi) are present in said immunoglobulin molecule.