Patent ID: 8822435
Filing Date: 2014-09-02
Classification: A61P,C07F

Abstract:
1. A method of treating osteoporosis, rheumatoid arthritis, osteoarthritis, Paget's disease, or alveolar bone loss comprising administering an effective amount of a compound of Formula I, or a pharmaceutically acceptable salt thereof to a patient in need of such treatment, wherein R a) hydrogen; b) halogen, —CN, —CF c) C d) C e) C f) optionally substituted aryl or optionally substituted heteroaryl; g) —C(O)R h) —C(O)OR i) —OR j) —OC(O)R k) —OC(O)OR l) —C(O)NR m) —OC(O)NR n) —SR o) —NR p) —NR q) —NR r) —OSO s) —SO t) —SO u) —NR v) —SO bb) R wherein m and n are each independently an integer from 0 to 2; Y is —CH p is an integer from 1 to 3; R Z is or each R R R