Patent ID: 8748097
Filing Date: 2014-06-10
Classification: C12Q,G01N

Abstract:
1. A method of identifying a candidate agent for diagnosis, monitoring, and/or treatment of a calcium disorder comprising steps of: (a) providing an agent that binds to or modulates expression, level, modification, localization, or activity of a C2orf28 (APR3), NELL1, NELL2, Phospholipase C-like 1(PLCL-1), Ephrin receptor B1 (EPHB1), or Syntrophin Gamma 1(SNTG1) gene product; and (b) testing the effect of the agent in a system that serves as a model for a calcium disorder, wherein the agent is identified as a candidate agent for treatment of a calcium disorder if the agent produces an effect in the system that is indicative of potential therapeutic efficacy for treatment of a calcium disorder.