Patent ID: 8940503
Filing Date: 2015-01-27
Classification: C12N,C12P

Abstract:
1. A process for the production of biomass from glucose comprising fermenting a recombinant microorganism selected from Gluconobacter oxydans , wherein the endogenous gene encoding membrane-bound glucose dehydrogenase is knocked-out in said microorganism, said microorganism producing at least 75% more biomass from glucose than the wild-type microorganism capable to express an endogenous membrane-bound glucose dehydrogenase after 24 hours in a bioconversion reaction comprising said fermenting and wherein the polynucleotide encoding the knocked-out glucose dehydrogenase is selected from the group consisting of: (i) nucleotide sequence according to SEQ ID NO:1; (ii) nucleotide sequence encoding a polypeptide according to SEQ ID NO:2; and (iii) nucleotide sequence obtainable from PCR using genomic DNA isolated from