Patent ID: 6770676
Filing Date: 2004-08-03
Classification: A61P,C07C

Abstract:
A 2-amino-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid compound having a relative stereochemical configuration represented by the formula: (wherein, R1 and R2 are the same or different, and each represents a hydrogen atom, a C1-10 alkyl group, a C3-8 cycloalkyl group, a C3-8 cycloalkyl C1-6 alkyl group, an aryl group, an aryl C1-6 alkyl group, a C1-6 alkoxy C1-6 alkyl group, an C1-6 hydroxyalkyl group, a C1-6 alkylthio C1-6 alkyl group, a C1-6 mercaptoalkyl group, a tetrahydrofuranyl group, or a tetrahydropyranyl group;in R3 and R4, when R3 is a hydroxyl group, R4 is a hydrogen atom; alternatively, R3 and R4 together form a Câ€”C single bond), a pharmaceutically acceptable salt thereof, or a hydrate thereof.