Patent ID: 8592570
Filing Date: 2013-11-26
Classification: A61P,C12N

Abstract:
1. A double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a West Nile virus (WNV) RNA in a cell, comprising: at least two sequences that are complementary to each other and wherein a sense strand comprises a first sequence and an antisense strand comprises a second sequence comprising a region of complementarity which is complementary to an mRNA encoding WNV, and wherein said region of complementarity is less than 30 nucleotides in length, and wherein said first sequence comprises at least 15 contiguous nucleotides of the nucleotide sequence of SEQ ID NO: 1 and said second sequence comprises at least 15 contiguous nucleotides of the nucleotide sequence of SEQ ID NO:2, and wherein said dsRNA, upon contact with a cell expressing said WNV, inhibits expression of said WNV RNA.