Patent ID: 6211220
Filing Date: 2001-04-03
Classification: A61K

Abstract:
A method of treating a mammal having precancerous lesions sensitive to the compounds below comprising administering a pharmacologically effective amount of a compound of Formula I ##STR5##or a pharmaceutically acceptable salt thereof, whereinAr is a heteroaryl ring selected from the group consisting of pyridyl, pyrimidyl, pyridazinyl, pyrazinyl, imidazolyl, thienyl, oxazolyl, benzimidazolyl, benzoxazolyl, or indolyl;X is CH;R.sup.0 is selected from the group consisting of NR.sup.1 R.sup.2 or hydrogen; andR.sup.1 and R.sup.2 are independently selected from the group consisting of hydrogen or C.sub.1-6 alkyl.