Patent ID: 8227589
Filing Date: 2012-07-24
Classification: C12Q

Abstract:
1. A biomarker consisting of between 6 and 35 different nucleic acid probe sets, wherein: (a) a first probe set consists of one or more nucleotide probes consisting of 15 or more contiguous nucleotides of SEQ ID NO:3 (BLCAP), or a full complement thereof; (b) a second probe set consists of one or more nucleotide probes consisting of 15 or more contiguous nucleotides of SEQ ID NO:5 (UBE2G1), or a full complement thereof; (c) a third probe set consists of one or more nucleotide probes consisting of 15 or more contiguous nucleotides of SEQ ID NO:6 (CALM3), or a full complement thereof; (d) a fourth probe set consists of one or more nucleotide probes consisting of 15 or more contiguous nucleotides of SEQ ID NO:13 (NONO), or a full complement thereof; (e) a fifth probe set consists of one or more nucleotide probes consisting of 15 or more contiguous nucleotides of SEQ ID NO:1 or SEQ ID NO:2 (RAP1A), or a full complement thereof; and (f) a sixth probe set consists of one or more nucleotide probes consisting of 15 or more contiguous nucleotides of SEQ ID NO:7 or SEQ ID NO:8 (GPX1), or a full complement thereof; wherein each of the between 6 and 35 different probe sets consists of one or more probes of 15 or more contiguous nucleotides, or full complements thereof, of a different mRNA, and wherein each of the different probe sets is optionally detectably labeled.