Patent ID: 8383655
Filing Date: 2013-02-26
Classification: A61K,A61P,C07C,C07D,C07K

Abstract:
1. A method for improving the pharmacokinetics of a drug which is metabolized by cytochrome P450 monooxygenase, comprising administering to a patient treated with the drug a therapeutically effective amount of a compound of formula IID, or a pharmaceutically acceptable salt thereof, wherein, L each L each L each A is independently selected from the group consisting of H, alkyl, substituted alkyl, aryl, substituted aryl, heterocyclyl, and substituted heterocyclyl, Z Y and X are each independently selected from the group consisting of heterocyclyl and heterocyclylalkyl; each Ar is independently selected from the group consisting of aryl, substituted aryl, heteroaryl, and substituted heteroaryl; R R R each R R each p is independently 0 or 1.