Patent ID: 8834884
Filing Date: 2014-09-16
Classification: A61K,A61P,C07K

Abstract:
1. A biodegradable sustained release intraocular drug delivery system in the form of microspheres for treating an ocular condition in a patient, the drug delivery system consisting of: (a) a water soluble therapeutic agent, (b) a polymeric carrier for the therapeutic agent, and (c) a release modifier associated with the therapeutic agent to permit the therapeutic agent to be released into the interior of an eye of an individual for at least about one week after the drug delivery system is placed in the eye, wherein the water soluble therapeutic agent is a protein, antibody, or antibody fragment, wherein the polymeric carrier is a poly-lactic acid (PLA), a poly-lactide-co-glycolide (PLGA), or a mixture thereof, and wherein the release modifier is 1-eicosanol.