Patent ID: 6399066
Filing Date: 2002-06-04
Classification: A61K,A61P,C07K,C12N,C12Q,C12R,G01N,Y10S

Abstract:
A method of producing monoclonal antibodies against a substantially pure coagulase-negative bacterial capsular polysaccharide adhesin of Staphylococcus epidermidis that binds to polymeric material comprising: propagating a hybridoma formed by fusing a cell capable of producing antibodies against said adhesin with a myeloma cell and harvesting the antibodies produced by said hybridoma, wherein said adhesin inhibits at a concentration of about 0.1 mg/ml, binding to said polymeric material of at least about 50% of cells of Staphylococcus epidermidis RP-62A, RP-62NA or F-3248.