Patent ID: 7351431
Filing Date: 2008-04-01
Classification: A61K,A61P

Abstract:
1. A method to produce a lyophilized formulation comprising a cis[((1R,2R)-1,2-cyclohexanediamine-N,N′)bis(tetradecanoyloxy)]platinum(II) as a main ingredient, comprising the following steps: (1) a step of dissolving a cis[((1R,2R)-1,2-cyclohexanediamine-N,N′)bis(tetradecanoyloxy)]platinum(II) in 2-methyl-2-propanol, (2) a step of adjusting a water content of said solution to 1.0-6.0 mg/mL, (3) a step of quickly freezing said solution, and (4) a step of lyophilizing said frozen solution.