Patent ID: 7470524
Filing Date: 2008-12-30
Classification: C12P

Abstract:
1. A method for producing an L-amino acid comprising cultivating an L-amino acid-producing E. coli bacterium in a culture medium which contains glucose as a carbon source to cause accumulation of the L-amino acid in the culture medium, and isolating the L-amino acid from the culture medium, wherein said bacterium has been modified to enhance an activity of L-arabinose permease as compared to a wild strain, by placing a gene encoding L-arabinose permease under the control of a potent promoter, wherein said gene encoding L-arabinose permease comprises a DNA selected from the group consisting of: (a) a DNA comprising nucleotides 1 to 1419 in SEQ ID NO: 1, and (b) a DNA which is hybridizable with nucleotides 1-1419 in SEQ ID NO: 1 under stringent conditions, and wherein said DNA encodes a protein having an activity of L-arabinose permease and having a homology of not less than 95% with respect to the entire amino acid sequence of SEQ ID NO: 2, and wherein said stringent conditions comprise washing at 60° C. at a salt concentration of 0.1×SSC and 0.1% SDS, for approximately 15 minutes.