Patent ID: 8114971
Filing Date: 2012-02-14
Classification: A61K,C07K

Abstract:
1. An isolated nucleic acid molecule encoding a lipoprotein or a biologically active fragment of said lipoprotein that mediates adhesion of Neisseria cells to human cells from a bacteria of the genus Neisseria , selected from the group consisting of (a) an isolated nucleic acid molecule that is a fragment of SEQ ID NO:1 and encoding a protein comprising SEQ ID NO:5; (b) an isolated nucleic acid molecule encoding a protein sharing 95% sequence identity with a fragment of SEQ ID NO:1 encoding SEQ ID NO:5 due to the degeneracy of the genetic code; (c) an isolated nucleic acid molecule comprising a nucleotide sequence that hybridizes under stringent hybridization conditions of 0.2×SSC, 0.1% SDS and 68° C. to