Patent ID: 7692006
Filing Date: 2010-04-06
Classification: A61P,C07D

Abstract:
1. A method of obtaining 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one (compound A) as crystalline Form A comprising the steps of: (i) crystallising 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one from a solvent; (ii) if the original solvent is not ethanol, treating the crystalline compound A with ethanol; (iii) treating the crystalline compound A containing trapped ethanol obtained from either step (i) or step (ii) with water to remove trapped ethanol; (iv) drying the resulting product.