Patent ID: 6027743
Filing Date: 2000-02-22
Classification: A61L

Abstract:
A device for forming a stable, functional, vitalized articulating skeletal joint at a joint defect site in a mammal, the device comprising:a biocompatible, bioresorbable, devitalized matrix, excised from a mammalian donor articulating skeletal joint and comprising,an articulating surface, and,plural distinct tissues including at least one non-mineralized tissue, said tissues capable of essentially maintaining their shape and relationships when used as a replacement joint, and having dimensions and structural relationships to each other which correspond anatomically to the articulating skeletal joint to be replaced, and, disposed on or within said matrix,substantially pure exogenous osteogenic protein in an amount sufficient to induce formation of a new vitalized articulating surface and new vitalized plural distinct tissues thereby to permit regeneration of said stable, functional, vitalized articulating skeletal joint at said defect site.