Patent ID: 9176105
Filing Date: 2015-11-03
Classification: B03B,B03D,G01N

Abstract:
1. A method of analyzing or separating a sample comprising one or more biological analytes of interest using a multi-phase system, comprising: a) providing a multi-phase system comprising two or more phase-separated solutions having a stable interface between adjacent phases, wherein each of the two or more phases has a different density and the phases, taken together, represent a density gradient; b) introducing a biological sample comprising one or more biological analytes of interest without disrupting the phase-separated solution; and c) allowing the biological analyte to migrate to a location in the multi-phase system that is characteristic of its density, wherein during migration the analyte contacts one or more of the two or more phases sequentially such that the analyte's final position in the system is not determined predominantly by partitioning.