Patent ID: 6825189
Filing Date: 2004-11-30
Classification: A61P,C07D

Abstract:
A compound represented by the formula any of its enantiomers or any mixture of enantiomers, isotopes thereof, or a pharmaceutically acceptable salt thereof; whereinR represents hydrogen, C1-8-alkyl, C3-7-cycloalkyl, or C3-7-cycloalkyl-C1-8-alkyl; and R1 represents a substituted phenyl selected from the group consisting of aminophenyl, nitrophenyl, hydroxyphenyl, and C1-8-alkoxyphenyl; or R1 represents a 3-pyridyl or a 2-pyrazinyl group, which group may be substituted one or more times with substituents selected from the group consisting of C1-8-alkyl, C2-6-alkynyl, C1-8-alkoxy, methoxymethoxy, methoxyethoxy, ethoxyethoxy, C3-7-cycloalkoxy, C2-6-alkenoxy, hydroxy-C1-8-alkoxy, C1-8alkylthio, halogen, hydroxy, CF3, trifluoromethanesulfonyloxy, carboxamido, phenyl, nitrophenyl, pyrrolidinyl, pyridyl, pyrrolyl, and indolyl; or R1 represents a 3-quinolinyl group.