Patent ID: 6365146
Filing Date: 2002-04-02
Classification: A61K,C08G,C08L

Abstract:
A polymer having a structure selected from the group consisting of:R(â€”Oâ€”R1)x and R(â€”NHâ€”R1)x wherein R(â€”Oâ€”)x is obtained from a polyol and R(â€”NHâ€”)x is obtained from a polyamine, with x being between 2 and 10, inclusive, and each R1 independently has the structure:â€”(â€”C(&boxH;O)â€”R2â€”NHâ€”)yâ€”(â€”C(&boxH;O)â€”R3â€”C(&boxH;O)â€”)zâ€”R4 whereinâ€”C(&boxH;O)â€”R2â€”NHâ€” is obtained from a divalent amino acid with R2 being a covalent bond or having from 1-8 carbon atoms, and y and z are between 0 and 10 inclusive, provided y and z are not both 0; â€”C(&boxH;O)â€”R3â€”C(&boxH;O)â€” is obtained from a divalent dicarboxylic acid in which R3 is an alkylene or cycloalkylene group containing from 1 to 15 carbon atoms, substituted with a total of from 1 to about 10 hydroxyl groups, with at least a portion of the hydroxyl groups being acylated with from 3 to about 24 carbon atom carboxylic acids; R4 is a poly(alkylene oxide) having the structure: R5â€”(R6â€”Oâ€”)aâ€”R6â€”Qâ€”R5 is selected from the group consisting of 1 to 40 carbon atom alkyl groups, â€”OH, â€”OR7, â€”NH2, â€”NHR7, â€”NHR7R8, â€”CH2â€”OH, â€”CH2â€”OR7,â€”CH2â€”Oâ€”CH2â€”R7, CH2â€”NH2, â€”CH2â€”NHR7 and CH2â€”NR7R8; R6, R7, and R8 are independently selected from the group consisting of 2 to 40 carbon atom, straight-chain or branched alkylene groups, Q is a divalent linkage moiety; and a is between 2 and 110, inclusive; provided that when y is 0 and R is a 1,1,1-tris(hydroxyphenyl)ethane moiety, the divalent dicarboxylic acid moiety is not an acylated mucic acid moiety.