Patent ID: 6011068
Filing Date: 2000-01-04
Classification: A01K,A61K,A61P,C07C,C07D,C07K,G01N

Abstract:
A compound having the chemical formula: ##STR15## wherein alk is selected from the group consisting of n-propylene, 2,4-butylene and 1,3-butylene;R.sub.1 is lower alkyl of from 1 to 3 carbon atoms or lower haloalkyl of from 1 to 3 carbon atoms substituted with from 1 to 7 halogen atoms; andR.sub.2 and R.sub.3 are independently selected monocyclic or bicyclic carbocyclic aryl or cycloalkyl groups, having 5- to 7-membered rings optionally substituted with 1 to 5 substituents independently selected from the group consisting of: OCF.sub.3, lower alkyl of 1 to 3 carbon atoms, lower haloalkyl of 1 to 3 carbon atoms substituted with 1 to 7 halogen atoms, lower alkoxy of 1 to 3 carbon atoms, halogen, nitro, amino, alkylamino, amido, lower alkylamido of 1 to 3 carbon atoms, cyano, hydroxy, acyl of 2 to 4 carbon atoms, lower hydroxyalkyl of 1 to 3 carbon atoms, and lower thioalkyl of 1 to 3 carbon atoms; provided that if R.sub.2 is phenyl, then said phenyl R.sub.2 has at least one substituent and is not 4-OH-phenyl; or a pharmaceutically acceptable acid addition salt or complex thereof.