Patent ID: 6800282
Filing Date: 2004-10-05
Classification: A61L,C12N

Abstract:
A wound dressing comprising:a carrier layer having a wound-facing surface, said carrying layer comprising a polymeric material adherent to anchorage dependent cells and treated on the wound-facing surface thereof to be non-adherent to cells, said polymeric material comprising a polymer selected from a group consisting of polyhydroxyethylmethacrylic acids, cross-lined polyvinylalcohols, polyacrylic acids cross-linked with trialkylsucrose, polyvinylpyrrolidones, polyetherpolyesters, polyetherpolyamides, polyacrylamides, polyethylene oxide, polyurethanes and ethylenevinyl acetate copolymers, said surface being non-adherent to anchorage-dependent cells and having disposed thereon a biodegradable cell anchoring layer comprising a material selected from the group consisting of: (i) a polyanion selected from the group consisting of a heparin, an inositol phosphate, fucoidin, syndecan, betaglycan, perlecan, dextran sulphate, pentosan, mesoglycan and polyvinyl sulphate; and (ii) a polycation comprising a polypeptide; and said anchoring layer having anchored thereto mammalian cells which form a cell layer comprising a material selected from the group consisting of keratinocytes and fibroblasts.