Patent ID: 7205312
Filing Date: 2007-04-17
Classification: A61P,C07D

Abstract:
1. A compound of formula its N-oxide forms, a pharmaceutically acceptable addition salt or a stereochemically isomeric form thereof, wherein: R R R Het represents an unsaturated heterocycle selected from imidazolyl, triazolyl, tetrazolyl and pyridinyl; wherein each of said unsaturated heterocycles may optionally be substituted with amino, mercapto, C  represents an unsaturated mono- or bicyclic heterocycle selected from the group consisting of pyridazinyl, pyrimidinyl, pyrazinyl, purinyl, phtalazinyl, cinnolinyl, quinazolinyl and quinoxalinyl; wherein each of said unsaturated mono- or bicyclic heterocycles may optionally be substituted with one, two or three substituents selected from hydroxy, halo, nitro, amino, C  represents a radical of formula wherein each X independently represents NR R —R aryl represents phenyl or phenyl substituted with one, two or three substituents selected from hydroxy, halo, cyano, amino, mono- or di(C with the proviso that: