Patent ID: 6165717
Filing Date: 2000-12-26
Classification: B01J,C07B,C07H,C07K,C40B,Y10S,Y10T

Abstract:
A method of preparing a library of diverse compounds, each of said compounds being prepared by step-by-step assembly of building blocks, said method comprising the steps of:a) apportioning solid supports among a plurality of reaction vessels; andb) in each reaction vessel of said plurality of reaction vessels, exposing said supports to a plurality of first building blocks and to a plurality of first identifier tags under conditions compatible with immobilization of the first building block and the first identifier tag,wherein said first building block is capable of being covalently coupled to a second building block or a second identifier tag;wherein said first identifier tag does not interfere with the coupling of said first building block to said second building block or said second identifier tag;wherein said first identifier tag in each of said reaction vessels identifies the first building block present in that vessel; and,wherein the first building block present in one reaction vessel is chemically different from the first building block found in the other reaction vessels.