Patent ID: 9051385
Filing Date: 2015-06-09
Classification: A61K,A61P,C07K,C12N,C12Y,Y10S

Abstract:
1. A polypeptide conjugate comprising an N-terminal moiety and a C-terminal moiety, wherein said N-terminal moiety comprises one or more ARF polypeptides and said C-terminal moiety comprises a polypeptide moiety that facilitates binding of said ARF polypeptide to an antigen presenting cell (APC), and wherein each said ARF polypeptide comprises at least 9 amino acids of an ARF polypeptide encoded by a human tyrosine kinase receptor (hHER-2) polynucleotide represented by SEQ ID NO: 2 and has a sequence selected from SEQ ID NOs: 71-95 and fragments thereof comprising at least 9 amino acids.