Patent ID: 8791148
Filing Date: 2014-07-29
Classification: A61K,A61P,C07D

Abstract:
1. A method for the treatment of a vasopressin-dependent disease selected from the group consisting of anxiety disorders, depressive disorders, and hyponatremia, the method comprising administering to a subject in need thereof a compound of the general formula (I), in which A A B is an aromatic, heteroaromatic, partly aromatic or partly heteroaromatic mono- or bicyclic ring having 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10 C atoms as ring members, which may additionally comprise 0, 1, 2, 3 or 4 identical or different heteroatoms independently of one another selected from the group consisting of nitrogen, oxygen and sulfur as ring members, and which may be substituted by one, two or three radicals R R R R R R R R R R R R R R R R R R R R R the tautomeric, enantiomeric and/or diastereomeric forms thereof, and the physiologically tolerated salts of the aforementioned compound or compounds; with the proviso that R 1 ≠H (is not hydrogen) when A 1 =A 2 =hydrogen; and with the proviso that R 1 is halogen, cyano, or in each case optionally substituted C 1 -C 6 -alkoxy or C 1 -C 6 -alkyl when A 1 =A 2 =hydrogen.