Patent ID: 7462326
Filing Date: 2008-12-09
Classification: G01N

Abstract:
1. A device for the detection of at least one ligand contained in a sample that is to be analyzed, said device comprising: an optical waveguide defining a single light path along which multiple detection fields and multiple radiation receivers are disposed, each detection field including at least one receptor for contacting a ligand to form a specific bond with the ligand; at least one optical source of radiation for injecting excitation radiation into the waveguide, the radiation being used for exciting the emission of luminescence radiation as a function of the bonding of ligands to receptors; and a semiconductor chip having said radiation receivers on a semiconductor substrate, each detection field having one radiation receiver associated therewith, each radiation receiver operative for detecting only the luminescence radiation sent out by the detection field associated therewith, wherein: the waveguide is monolithically integrated with the semiconductor substrate or is in the form of a waveguide layer located on the semiconductor chip; and the radiation receiver associated with each detection field is integrated into the semiconductor substrate facing the detection field directly on the back side of the waveguide facing away from the detection field.