Patent ID: 8022209
Filing Date: 2011-09-20
Classification: A61P,C07D

Abstract:
1. A process for the preparation compounds of formula (I-P), pharmaceutically acceptable salts of compounds of Formula (I-P), pharmaceutically acceptable prodrugs of compounds of Formula (I-P), and pharmaceutically active metabolites of compounds of Formula (I-P), wherein A is selected from the group consisting of H and C R wherein said aryl or heteroaryl is optionally substituted with one or more substituents independently selected from the group consisting of halo, hydroxy, C R Sph is phenyl substituted with one or more substituents independently selected from the group consisting of halo, cyano, C R R a is 1; R comprising: reacting a compound of formula (XIII) with a compound of formula (XV) in an anhydrous organic solvent.