Patent ID: 6720333
Filing Date: 2004-04-13
Classification: C07D

Abstract:
A compound of the formula (I): whereinX is ethylene, propylene, or butylene; Y is â€”COâ€”; Z is a bond; R1 is aryl, heteroaryl, C1-10 alkyl, or C2-10 alkenyl, each of which may be unsubstituted or substituted by one or more substituents independently selected from the group consisting of: -alkyl; -aryl; -substituted aryl; -heteroaryl; â€”O-alkyl; â€”O-(alkyl)0-1 aryl; â€”COâ€”O-alkyl; -halogen; -haloalkyl; -haloalkoxy; and â€”CN; R2 is selected from the group consisting of: -hydrogen; â€”C1-10 alkyl; and â€”C1-10 alkyl-Oâ€”C1-10 alkyl; R3 and R4 are independently selected from the group consisting of hydrogen, and methyl; R5 is H or C1-10 alkyl, or R5 can join with X to form a ring; or a pharmaceutically acceptable salt thereof.