Patent ID: 6991775
Filing Date: 2006-01-31
Classification: A61K,C07K

Abstract:
1. A purified peptide comprising the amino acid sequence: P*-Y*-X 1 *-L* (SEQ ID NO:1), wherein: P* is a proline or its non-natural derivative 4-hydroxyproline; Y* is a tyrosine or its non-natural derivative substituted at the 3 position with a moiety selected from the group consisting of F, Cl, Br, I, and NO provided that at least one of said P* or Y* is said non-natural derivative of the respective amino acid; X L* is a leucine or a non-natural derivative of leucine selected from the group consisting of N-methylleucine, Norleucine, tert-leucine, and the d isomer of leucine.