Patent ID: 7511066
Filing Date: 2009-03-31
Classification: C04B,C07C,C07D

Abstract:
1. A compound of formula I, or a pharmaceutically acceptable salt thereof, wherein: A one of A each of R A two adjacent residues of A L is carbonyl or methylene; R is 2-pyridinyl (which may bear a methyl, cyano, carbamoyl, hydroxymethyl, formyl, vinyl, amino, hydroxy, methoxy, difluoromethoxy, methylthio, fluoro or chloro substituent at the 5-position), or R is 3-pyridinyl (which may bear a methyl, fluoro or chloro substituent at the 6-position), or R is 2-thiazolyl (which may bear a methyl substituent at the 4-position or a bromo substituent at the 5-position), or R is phenyl (which may bear one, two or three substituents at the 3-, 4- or 5-position(s) independently selected from fluoro, chloro, bromo, cyano, carbamoyl, methyl, methoxy, difluoromethoxy, hydroxymethyl, formyl, vinyl, amino, hydroxy and 3,4-methylenedioxy; and in addition the phenyl may bear a 2-chloro or 2-fluoro substituent), or R is 6-indolyl (which may bear a chloro or methyl substituent at the 3-position); R a) Q is a single bond; the sum of i and j is 2 or 3; and each of R b) Q is —CH(CH c) Q is cyclohexane-1,4-diyl; each of i and j is 0; R d) Q is —CHR e) Q is —CHR f) Q is —CHR R