Patent ID: 6359118
Filing Date: 2002-03-19
Classification: A61K,C07K,C12N,Y10S

Abstract:
A crosslinked glycoprotein crystal, said crosslinked glycoprotein crystal having each of the following characteristics:(a) said crosslinked glycoprotein crystal comprises a three dimensional crystal lattice; (b) said crosslinked glycoprotein crystal is in a shape selected from the group consisting of spheres, needles, rods, plates, rhomboids, cubes, bipyramids and prisms; (c) said crosslinked glycoprotein crystal is crosslinked through carbohydrate-to-carbohydrate crosslinking of one or more carbohydrate moieties within the crystal lattice; and (d) said crosslinked glycoprotein crystal displays enhanced stability as compared to an uncrosslinked counterpart glycoprotein.