Patent ID: 8367824
Filing Date: 2013-02-05
Classification: C07C,C07D

Abstract:
1. A process for preparing a quinazolin-4-one compound having the formula (2): in which each of R 1 , R 2 , R 3 and R 4 independently represents a hydrogen atom, an alkyl group, a cycloalkyl group, an aralkyl group, an aryl group, a halogen atom, a hydroxyl group, an alkoxy group, an alkylthio group, nitro, cyano, or carbonyl, which comprises reacting an anthranilic acid compound having the formula (1): in which R 1 , R 2 , R 3 and R 4 have the same meaning as above, and R 5 represents a hydrogen atom or a hydrocarbyl group selected from the group consisting of methyl, ethyl, propyl, butyl, pentyl and hexyl, with methyl orthoformate or ethyl orthoformate in the presence of an ammonium carboxylate.