Patent ID: 6321164
Filing Date: 2001-11-20
Classification: G01N,G16H

Abstract:
A method for predicting the presence of an abnormal level of one or more proteins of a coagulation cascade from at least one time-dependent measurement profile, comprising,a) performing at least one time-dependent measurement on an unknown sample of a property over time, which property changes when said sample undergoes coagulation, so as to derive at least one time-dependent measurement profile;b) defining a set of a plurality of predictor variables which sufficiently define at least one time-dependent measurement profile;c) deriving a model that represents the relationship between the abnormal level of said one or more proteins in the clotting cascade and the set of a plurality of predictor variables; andd) utilizing the model of step c) to predict the existence of an abnormal level of said one or more proteins in said coagulation cascade and to predict which protein or proteins in said coagulation cascade are said one or more proteins which are at an abnormal level as compared to a known sample.