Patent ID: 6015900
Filing Date: 2000-01-18
Classification: A61P,C07C,C07D

Abstract:
A compound of the formula ##STR66## or pharmaceutically acceptable salts thereof wherein: G represents a group of the formula ##STR67## where R.sub.a and R.sub.b independently represent hydrogen, C.sub.1 -C.sub.6 alkyl, hydroxy, C.sub.1 -C.sub.6 alkoxy or mono- or di-C.sub.1 -C.sub.6 alkylamino;A is a C.sub.2 -C.sub.6 alkylene optionally substituted with one or more alkyl groups having from one to four carbon atoms;R.sub.1, R.sub.2, R.sub.3, R.sub.4 are the same or different and represent hydrogen, C.sub.1 -C.sub.6 alkyl, halogen, hydroxy, amino, cyano, nitro, trifluoromethyl, trifluoromethoxy, C.sub.1 -C.sub.6 alkoxy, --O.sub.2 CR', --NHCOR', --COR', --SO.sub.m R', where R' is C.sub.1 -C.sub.6 alkyl and wherein m is 0, 1 or 2; orR.sub.1, R.sub.2, R.sub.3, R.sub.4 independently represent --CONR'.sub.m, or --NR'.sub.m where m is 0, 1 or 2 and R' is hydrogen or C.sub.1 -C.sub.6 alkyl;R.sub.5 is hydrogen or C.sub.1 -C.sub.6 alkyl;R.sub.6 and R.sub.7 are the same or different and are hydrogen or C.sub.1 -C.sub.6 alkyl; andW is phenyl, naphthyl, 1-(5,6,7,8-tetrahydro)naphthyl or 4-(1,2-dihydro)indenyl, pyridinyl, pyrimidyl, isoquinolinyl, benzofuranyl, benzothienyl, each of which is optionally mono-, di-, or trisubstituted with halogen, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.6 thioalkoxy, hydroxy, amino, mono or dialkylamino where each alkyl is C.sub.1 -C.sub.6 alkyl, cyano, nitro, trifluoromethyl or trifluoromethoxy.