Patent ID: 6087509
Filing Date: 2000-07-11
Classification: A61K,A61P,C07D

Abstract:
A compound selected from the group consisting of 4-(4,4-bis(fluoromethyl)-2,5-dioxo-3-(4-hydroxy-2-butyn-1-yl)-1-imidazolid inyl)-2-(trifluoromethyl)-benzonitrile, 4-(3-(4-hydroxy-2-butyn-1-yl) -4,4-dimethyl-2,5-dioxo-1-imidazolidinyl)-2-(trifluoromethyl)-benzonitrile , 4-[2,4-dioxo-1-(4-hydroxybutyl)-1,3-diazaspiro[4,5]decan-3-yl]-2-(trifluo romethyl)-benzonitrile and the addition salts with non-toxic, pharmaceutically acids.