Patent ID: 8968706
Filing Date: 2015-03-03
Classification: A61K,A61P,C12Q,G01N,Y02A

Abstract:
1. A method comprising: (i) detecting a cyclic nucleotide level in a human nasal mucus or human saliva specimen; (ii) comparing the cyclic nucleotide level of the nasal mucus or saliva specimen to a cyclic nucleotide level of a control population; and (iii) diagnosing loss or distortion of taste in the human based on a decreased level of the cyclic nucleotide for the nasal mucus or saliva specimen compared to the cyclic nucleotide level of the control population, wherein the cyclic nucleotide level is detected by an immunoassay; and wherein the method further comprises determining at least one of a detection threshold (DT), a recognition threshold (RT), or a magnitude estimation (ME) for four tastants: sodium chloride (NaCl), sucrose, hydrogen chloride (HCl) and urea.