Patent ID: 6096764
Filing Date: 2000-08-01
Classification: A61K,A61P

Abstract:
A method of inhibiting GnRH or GnRH agonist induced detrimental side-effects due to administration of GnRH or a GnRH agonist to a mammal, comprising administrating to a mammal in need thereof an effective amount of a compound of formula I ##STR5## wherein R.sup.1 and R.sup.2 are, independently, --H, --CH.sub.3, --CO(C.sub.1 -C.sub.6 alkyl) or --COAr, where Ar is optionally substituted phenyl;R.sup.3 is selected from the group consisting of pyrrolidine, piperidine, and hexamethyleneimino; ora pharmaceutically acceptable salt or solvate thereof.