Patent ID: 8426008
Filing Date: 2013-04-23
Classification: B01J,B01L,B05D,B82Y,C07B,C12Q,C40B,Y10S,Y10T

Abstract:
1. A medical device comprising at least one distinct region of length L and width W of the surface of the device covered by a mixed monolayer film, the mixed monolayer film comprising a species having a functional group M1 and a species having a functional group M2 where M1 and M2 have different surface eneries, the mixed monolayer forming a surface energy gradient from proximal location to a distal location within the region wherein L equals the distance from the proximal location to the distal location, W is 20 nanometers or greater, and the ratio of L/W is greater than 2 and wherein at least one of the species comprises a biopolymer-resistant domain and wherein any portions of the surface that border the at least one distinct region along the dimension L have substantially equal surface energies.