Patent ID: 7763706
Filing Date: 2010-07-27
Classification: A23J,A23L,A23V,A61K,A61P,C07K

Abstract:
1. A process for the preparation of a mixture of peptides by cationic exchange chromatography, having an arginine and lysine content of at least 20 w/w %, based on the total amount of protein, from at least one protein source, comprising the steps of: a) cleaving the proteins of at least one protein source into peptides; b) allowing the peptides to bind to cation exchange resin; c) washing the cation exchange resin with an alkaline wash solution having a hydroxide normality of 0.05-2.0; and d) eluting bound peptides from the resin with an aqueous elution solution having an ionic strength of at most 200 mM and a pH between 5.0-9.0.