Patent ID: 7838525
Filing Date: 2010-11-23
Classification: A61P,C07D

Abstract:
1. A method for treatment of a metabolic-related disorder selected from type I diabetes, inadequate glucose tolerance, insulin resistance, hyperglycemia, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, dyslipidemia, and syndrome X in an individual comprising, administering to said individual in need of such treatment a therapeutically effective amount of a compound of Formula (I): or a pharmaceutically acceptable salt, hydrate or solvate, or N-oxide thereof; wherein: A and B are each independently C D is S, S(O), S(O) E is N or CR V V W is NR Q is NR X is N; Y is N; Z is selected from the group consisting of C Z is a group of Formula (A): wherein: R R Ar R wherein: “p” and “r” are each independently 0, 1, 2 or 3; and R R two adjacent groups selected from the group consisting of R R R R R wherein: R R wherein: G is: —CR wherein R R