Patent ID: 8637672
Filing Date: 2014-01-28
Classification: A61K,A61P,C07D

Abstract:
1. A compound of Formula I, or a pharmaceutically acceptable salt, enantiomer, stereoisomer, or tautomer thereof, wherein X is halogen; Z1 and Z2 are CR2; Z3 is CH; each R1 is independently and individually halogen, H, C1-C6 alkyl, branched C3-C7 alkyl, C3-C7 cycloalkyl, or —CN; each R2 is individually and independently H, halogen, C1-C6 alkyl, or cyano; each cycloalkyl, aryl, heteroaryl and heterocyclyl is independently substituted with —(R25) each R25 is individually and independently C1-C6 alkyl, branched C3-C8 alkyl, halogen, —(CH each m is individually and independently 0, 1, 2, or 3; and p is 1, 2, or 3.