Patent ID: 8178672
Filing Date: 2012-05-15
Classification: A61P,C07D

Abstract:
1. A method for preparing a compound of formula I, or a pharmaceutically acceptable salt thereof comprising: (a) reacting a compound of formula III with N,N-dimethylformamide of formula IV and (b) reacting said compound of formula IV with a guanidino compound of formula V: to form said compound of formula I, wherein: X is O or S(O) Ar is 2,3-dihydro-benzo[1,4]dioxin-6-yl; benzo[1,3]dioxol-5-yl; an aryl group; or an aryl group substituted with one or more substituents independently selected from the group consisting of halogen; —CN; —NO R R R R R R R