Patent ID: 6632822
Filing Date: 2003-10-14
Classification: A61P,C07D

Abstract:
A compound of Formula (I): whereinR is selected from hydrogen, alkyl, acyl, carboxyalkyl, carboalkoxyalkyl; m and n are independently selected from 0, 1, 2; each Y and each Z are independently selected from halo, acyl, nitro, amino, alkylamino, acylamino, hydroxy, acyloxy, alkoxy, alkyl, CO2H, CO2alkyl, CONX2 (where each X is independently, H or alkyl), SO3H, SO2NX2 (wherein each X is independently H or alkyl), nitrile, formyl, carboxyalkyl, carboalkoxyalkyl; a, b, c and d are independently selected from hydrogen, hydroxy, alkoxy, acyloxy, alkyl; or, a and b together and/or c and d together independently form a carbonyl group (C&boxH;O), an imine group (C&boxH;Nâ€”R1, where R1 is alkyl, hydroxy, alkoxy or amino NR2R3), or an alkene group (C&boxH;CR2R3, where R2 and R3 are independently hydrogen or alkyl) wherein the Compound of Formula (I) is as the N-oxide or unoxidized base, or salt, derivative or prodrug thereof.