Patent ID: 8501937
Filing Date: 2013-08-06
Classification: C07B,C07C,C07D,C40B

Abstract:
1. A method of synthesizing a hydroxyethylamino amide of Formula (I): wherein: R R R an enantiomer, a diastereomer, a tautomer, or a pharmaceutically acceptable salt thereof, the method comprising: (a) preparing a epoxymethylated support of formula (Ia) (b) reacting the support of formula (Ia) with an R (c) reacting the epoxymethylated amido support of formula (Ib) with an R (d) reacting the hydroxyethylamino amido support of formula (Ic) with an R and (e) cleaving the hydroxyethylamino amide of formula (I) from the hydroxyethylamino amido support of formula (Id).