Patent ID: 7888426
Filing Date: 2011-02-15
Classification: C08L,G02B

Abstract:
1. A polymerizable material for making an ophthalmic device comprising: (a) a water-soluble polyvinyl alcohol having crosslinkable groups; and (b) nanoparticles having a hydrophilic surface, wherein component (b) is presented in the polymerizable material in an amount sufficient to improve one or more physical properties of the ophthalmic device made from the polymerizable material, wherein the one or more physical properties are selected from the group consisting of stress at break (N/mm 2 ), percentage of elongation at break, toughness or energy to break (N·mm), and susceptibility to fracture, wherein said water-soluble polyvinyl alcohol is a polyhydroxyl compound which has a weight average molecular weight of at least about 2000 and which comprises from about 0.5 to about 80%, based on the number of hydroxyl groups in the poly(vinyl alcohol), of units of the formula I, I and II, I and III, or I and II and III in which R is alkylene having up to 12 carbon atoms, R 1 is hydrogen or lower alkyl, R 2 is an olefinically unsaturated, electron-withdrawing, crosslinkable radical having up to 25 carbon atoms, and R 3 is hydrogen, a C 1 -C 6 alkyl group or a cycloalkyl group, wherein R and R 3 are as defined above, and R 7 is a primary, secondary or tertiary amino group or a quaternary amino group of the formula N + (R′) 3 X − , in which each R′, independently of the others, is hydrogen or a C 1 -C 4 alkyl radical and X is HSO 4 − , F − , Cl − , Br − , I − , CH 3 COO − , OH − , BF − , or H 2 PO 4 − , in which R and R 3 are as defined above, and R 8 is the radical of a monobasic, dibasic or tribasic, saturated or unsaturated, aliphatic or aromatic organic acid or sulfonic acid.