Patent ID: 6288276
Filing Date: 2001-09-11
Classification: C07C

Abstract:
A process for making an oxime of the formula IV ##STR14##wherein each of R.sub.2 -R.sub.5 is independently hydrogen, a halogen, an alkyl or cycloalkyl group having from 1 to 36 carbon atoms, an aryl or alkaryl group having from 1 to 36 carbon atoms, an alkoxy or an aryloxy group having from 1 to 30 carbon atoms, or an acyl group having from 1 to 24 carbon atoms which comprises the steps of: (1) reacting a compound of the formula I ##STR15##wherein each of R.sub.1 -R.sub.5 is independently hydrogen, a halogen, an alkyl or cycloalkyl group having from 1 to 36 carbon atoms, an aryl or alkaryl group having from 1 to 36 carbon atoms, an alkoxy or an aryloxy group having from 1 to 30 carbon atoms, or an acyl group having from 1 to 24 carbon atoms with the proviso that one of R.sub.1 or R.sub.5 is hydrogen with magnesium alkoxide to form an aryloxy magnesium compound; (2) reacting the aryloxy magnesium compound with a compound capable of forming a non-aryloxy anion X wherein X is selected from the group consisting of acetate, sulfate, nitrate, sulfonate, hydroxide, oxide, carboxylate and formate; to form an aryloxy magnesium salt of the formula II ##STR16##wherein R.sub.1 -R.sub.5, and X are defined as above and N is an integer having a value of 1 or 2; (3) reacting the aryloxy magnesium salt of the formula II with formaldehyde to yield an aldehyde of the formula III ##STR17##wherein R.sub.2 -R.sub.5 are defined as above; (4) reacting the aldehyde of the formula III with hydroxylamine to produce an oxime of the formula IV.