Patent ID: 7238664
Filing Date: 2007-07-03
Classification: A61K,A61P

Abstract:
1. A method for treating or reducing the onset of symptoms of a disease in which pulmonary surfactant malfunction and/or phosphodiesterase 5 (PDE5) activity is detrimental, or treating or reducing the severity of a disease in which pulmonary surfactant malfunction and/or phosphodiesterase 5 (PDE5) activity is detrimental in a patient, comprising administering intratracheally or intrabronchially to a patient in need thereof an effective amount of (1) Lusupultide and (2) Sildenafil or a pharmaceutically acceptable salt thereof wherein the disease in which pulmonary surfactant malfunction and/or phosphodiesterase 5 (PDE5) activity is detrimental is selected from the group consisting of COPD, bronchitis, bronchial asthma, pulmonary fibroses, emphysema, interstitial pulmonary disorders, pneumonia, ALI, ARDS and asthma bronchiale.