Patent ID: 6541211
Filing Date: 2003-04-01
Classification: B01J,B01L,B82Y,C40B,G01N,Y10T

Abstract:
A method of synthesizing combinatorial libraries comprising:providing Q numbers of 2-D frames, each an array of N rows by M columns of holes with supports inserted therein, wherein the supports in each hole of a column have attached the same building block diverse from the building blocks attached to the supports in the holes of the other columns; immersing said 1 to Q 2-D frames into respective 1 to Q reactors, each having different reagents, thereby allowing each support building block to react with a respective reagent; separating each 2-D frame into N subframes, each consisting of an individual 1 by M row of said 2-D frame; regrouping one subframe from the same row of each original 2-D frame to form N numbers of 2-D frames, each an array of Q rows by M columns of holes with supports inserted therein; and immersing the 1 to N 2-D frames into a respective set of 1 to N reactors, each containing a different reagent.