Patent ID: 8288116
Filing Date: 2012-10-16
Classification: A61K,C12N,G01N,Y10T

Abstract:
1. A capture system for removing cancer cells from a blood fluid containing a mixed population of cancer cells and non-cancer cells, said fluid selected from the group consisting of whole blood, lymph, bone marrow, ascites or a combination thereof, said system comprising a vessel, said vessel comprising a cell-adhesion matrix having a fibrous scaffold coated with at least one adhesion molecule, said fibrous scaffold comprising type I collagen fibers, type III collagen fibers, fibrin, cotton fibers, tissue fragment or plastic fibers, wherein said cancer cells are isolated by incubating the mixed population of cells for a time sufficient to allow said cancer cells to ingest the matrix and isolating said cancer cells that ingest the matrix from cells that do not ingest the matrix.