Patent ID: 7238832
Filing Date: 2007-07-03
Classification: B01J,C07B,C07C

Abstract:
1. A method for producing a coupling compound of formula (1): wherein R 1 , R 2 n and n′ are as defined below, Y is R which method comprises reacting an organic halogen compound of formula (2): wherein X R n and n′ each independently represent an integer of 1 or 2, and provided that n and n′ do not simultaneously represent 2, with an organic boron compound of formula (3): wherein R X n′ is as defined above, m represents an integer of 1 or 2, and m is not more than n, in the presence of a catalyst comprising a) a nickel compound, and b) b-1) a compound of formula (i): wherein R an alkyl, aryl, alkenyl, alkynyl, alkoxyl, hydroxy, hydroxyalkyl, sulfo, alkyloxycarbonyl, aryloxycarbonyl, carbamoyl, cyano, isocyano, cyanato, isocyanato or formyl group, or a hydrocarbylsilyl group, and optionally two adjacent groups among R a and b are the same or different and independently represent an integer of 0 to 4, or b-2) a compound of formula (ii): wherein R an alkyl, aryl, alkenyl, alkynyl, alkoxyl, hydroxy, sulfo, alkyloxycarbonyl, aryloxycarbonyl, carbamoyl, cyano, isocyano, cyanato, isocyanato or formyl group, or a hydrocarbylsilyl group, and optionally two adjacent groups among R c, and e are the same or different and independently represent an integer of 0 to 3, and d represents an integer of 0 to 2; or a mixture thereof.