Patent ID: 6506370
Filing Date: 2003-01-14
Classification: A61K,A61Q

Abstract:
A composition for percutaneous administration which promotes growth of hair-follicles, comprising, as an active ingredient, at least one selected from the group consisting of protein kinase C-specific inhibitors and pharmaceutically acceptable salts thereof, in a vehicle, wherein the protein kinase C-specific inhibitor is a protein kinase inhibitor in which a ratio of its 50% protein kinase A-inhibiting constant to its 50% protein kinase C-inhibiting constant is not smaller than 3.0, the active ingredient being included in an amount effective to promote growth of hair follicles, wherein the protein kinase C-specific inhibitor is selected from the group consisting of calphostin C, palmitoyl-DL-carnitine and hexadecylphosphocholine, wherein said vehicle is a carrier for a hair-follicle growing preparation, said carrier containing ethanol, and wherein the composition contains 55-90% ethanol.