Patent ID: 8835359
Filing Date: 2014-09-16
Classification: C12Q

Abstract:
1. A method for identifying a compound involved in neuropathic pain comprising the steps of: a) providing a cell-based system comprising a cytotoxic T lymphocyte-associated protein 2 beta (Ctla2b) nucleic acid encoding a protein comprising the amino acid sequence of either SEQ ID NO: 1 or 2, b) contacting the cell-based system with a test compound, and c) determining an effect of the test compound on the cell-based system, wherein the test compound is identified as a compound involved in neuropathic pain when the test compound causes a statistically significant increase in the level of Ctla2b nucleic acid encoding a protein comprising the amino acid sequence of either SEQ ID NO: 1 or 2 relative to the same cell-based system that was not contacted with the test compound.