Patent ID: 7709498
Filing Date: 2010-05-04
Classification: A61K,A61P,C07D,Y02A

Abstract:
1. A method for the treatment of a person suffering from a bacterial infection which comprises administering to said patient a therapeutically effective amount of a compound of formula a pharmaceutically acceptable acid or base addition salt thereof, a stereochemically isomeric form thereof or a N-oxide form thereof, wherein R p is an integer equal to 1 or 2; R R R R R two vicinal R r is an integer equal to 1 or 2; R Ar is a homocycle selected from the group of phenyl, naphthyl, acenaphthyl, tetrahydronaphthyl, each homocycle may optionally be substituted with 1, 2 or 3 substituents, each substituent independently selected from the group of hydroxy, halo, cyano, nitro, amino, mono- or di(C Het is a monocyclic heterocycle selected from the group of N-phenoxypiperidinyl, piperidinyl, pyrrolyl, pyrazolyl, imidazolyl, furanyl, thienyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, pyridinyl, pyrimidinyl, pyrazinyl and pyridazinyl; each monocyclic heterocycle may optionally be substituted with 1, 2 or 3 substituents, each substituent independently selected from the group of halo, hydroxy, C Het provided that the bacterial infection is other than a Mycobacterial infection; and provided that the compound is other than (αS, βR)-6-bromo-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-3-quinolineethanol, a pharmaceutically acceptable acid or base addition salt thereof or a N-oxide form thereof.