Patent ID: 6780994
Filing Date: 2004-08-24
Classification: A61P,C07D

Abstract:
A method of making a compound of Formula II wherein R8 is hydrogen; R9 is C3-6alkyl, or substituted C3-6alkyl â€ƒwhere the alkyl substituents are independently selected from one or more halogens; R10 is hydrogen; R11 is hydrogen comprisingreacting a compound of Formula II wherein R8 is hydrogen; R9 is C3-6alkyl, or substituted C3-6alkyl â€ƒwhere the alkyl substituents are independently selected from one or more halogens; R10 is hydrogen; R11 is benzyl, or substituted benzyl â€ƒwhere the benzyl substituents are independently selected from one or more members of the group consisting of C1-5alkyl, halogen, C1-5alkoxy, and nitro; with a reducing agent to give a compound of Formula II wherein R8 is hydrogen; R9 is C3-6alkyl, or substituted C3-6alkyl â€ƒwhere the alkyl substituents are independently selected from one or more halogens, R10 is hydrogen; R11 is hydrogen.