Patent ID: 6235750
Filing Date: 2001-05-22
Classification: A61P,C07D

Abstract:
A compound of the formula ##STR13##wherein R.sup.1 and R.sup.2 are selected, independently, from hydrogen, hydroxy, methyl and methoxy;G is selected from a group of the formula ##STR14##n is one;Y is hydrogen, (C.sub.1 -C.sub.6)alkyl, or aralkyl, wherein the aryl moiety of said aralkyl is phenyl, naphthyl, isoxazolyl, methylenedioxybenzyl, imidazolyl, pyridyl, furyl, thiazolyl, or isothiazolyl, and the alkyl moiety is straight or branched and contains from 1 to 6 carbon atoms, and wherein said (C.sub.1 -C.sub.6)alkyl and the aryl moiety of said aralkyl may be substituted with from zero to three substituents, that are selected, independently, from phenyl, --C(O)NH.sub.2, --C(O)phenyl, chloro, fluoro, bromo, iodo, nitro, hydroxy, cyano, amino, (C.sub.1 -C.sub.4)alkoxy and (C.sub.1 -C.sub.4) alkylamino;X is N; andq is zero, one or two;or a pharmaceutically acceptable salt of such compound.