Patent ID: 6093385
Filing Date: 2000-07-25
Classification: A61K,A61P,A61Q,C07C

Abstract:
The method of using 4,4-diarylbutadienes of the formula I, ##STR17## where the diene system has the Z,Z; Z,E; E,Z or E,E configuration or a mixture thereof, and where the variables independently of one another have the following meanings:R.sup.1 and R.sup.2 hydrogen, C.sub.1 -C.sub.20 -alkyl, C.sub.2 -C.sub.10 -alkenyl, C.sub.3 -C.sub.10 -cycloalkyl, C.sub.3 -C.sub.10 -cycloalkenyl, C.sub.1 -C.sub.12 -alkoxy, C.sub.1 -C.sub.20 -alkoxycarbonyl, C.sub.1 -C.sub.12 -alkylamino, C.sub.1 -C.sub.12 -dialkylamino, aryl, hetaryl, unsubstituted or substituted substituents which confer solubility in water and are selected from the group consisting of carboxylate, sulfonate or ammonium radicals;R.sup.3 hydrogen, COOR.sup.5, COR.sup.5, CONR.sup.5 R.sup.6, CN;R.sup.4 COOR.sup.6, COR.sup.6, CONR.sup.5 R.sup.6 ;R.sup.5 hydrogen, [X].sub.o -R.sup.7, C.sub.1 -C.sub.6 -alkylene-SO.sub.3 Y, C.sub.1 -C.sub.6 -alkylene-PO.sub.3 Y, C.sub.1 -C.sub.6 -alkylene-N(R.sup.8).sub.3.sup.+ A.sup.- ;R.sup.6 [X].sub.o -R.sup.7, C.sub.1 -C.sub.6 -alkylene-SO.sub.3 Y, C.sub.1 -C.sub.6 -alkylene-PO.sub.3 Y, C.sub.1 -C.sub.6 -alkylene-N(R.sup.8).sub.3.sup.+ A.sup.- ;X --CH.sub.2 --CH.sub.2 --Z--, --CH.sub.2 --CH.sub.2 --CH.sub.2 --Z--, --CH(CH.sub.3)--CH.sub.2 --Z--, --CH.sub.2 --CH.sub.2 --CH.sub.2 --CH.sub.2 --Z--, --CH.sub.2 --CH(CH.sub.2 --CH.sub.3)--Z--;A Cl, Br, I, SO.sub.4 R.sup.9 ;Y hydrogen, Na.sup.+, K.sup.+, Mg.sup.2+, Ca.sup.2+, Li.sup.+, Al.sup.3+, N(R.sup.8).sub.4.sup.+ ;Z O, NH;R.sup.7 and R.sup.8 hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.2 -C.sub.6 -alkenyl, C.sub.1 -C.sub.6 -acyl;R.sup.9 hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.2 -C.sub.6 -alkenyl;n 1 to 3;o 1 to 150as water-soluble photostable UV filters in cosmetic and pharmaceutical preparations for protecting the human skin or human hair from the sun's rays, alone or together with compounds which absorb in the UV region and are known for cosmetic and pharmaceutical preparations.