Patent ID: 8078243
Filing Date: 2011-12-13
Classification: A61B

Abstract:
1. A method of determining a tissue state of the tissue of an individual, where “tissue state” comprises any of (i) presence or likelihood of diabetes; (ii) the degree of progression of diabetes; (iii) a change in the presence, likelihood, or progression of diabetes; (iv) a probability of having, not having, developing, or not developing diabetes; (v) the presence, absence, progression, or likelihood of complications from diabetes, in each case based on long-term changes (greater than one month duration) in tissue comprising: a. Illuminating a portion of the tissue of the individual with excitation light; b. Detecting light emitted from the tissue by fluorescence of a chemical within the tissue, where the tissue is not the lens of the eye; c. Determining the tissue state from the detected light and a model relating fluorescence and a tissue state.