Patent ID: 7795401
Filing Date: 2010-09-14
Classification: C07K

Abstract:
1. A modified hemoglobin conjugated with an allosteric effector comprising: a hemoglobin composition prepared by conjugating a peptide comprising SEQ ID NO: 1 on a hemoglobin through a maleimide-PEG-N-hydroxysuccinimidyl under a deoxy condition; wherein, the peptide comprising SEQ ID NO: 1 is bonded via the cysteine residue therein through the maleimide functional group contained in the maleimide-PEG-N-hydroxysuccinimidyl under a deoxy condition, and the hemoglobin is bonded via the lysine residue on the surface through the N-hydroxysuccinimidyl functional group contained in the maleimide-PEG-N-hydroxysuccinimidyl under a deoxy condition.