Patent ID: 6027727
Filing Date: 2000-02-22
Classification: A61K,A61P,C07K,Y10S

Abstract:
A method for inducing transient infertility in a mammal, which method comprises administering to a subject mammal, a dose of a recombinant ZPB polypeptide selected from the group consisting of feline ZPB as set out in SEQ ID NO. 16; bovine ZPB as set out in SEQ ID NO. 22; cynomolgous monkey ZPB as set out in SEQ ID NO. 45; and human ZPB as set out in SEQ ID NO. 41 or an immunologically active fragment thereof, wherein the ZPB polypeptide or immunologically active fragment thereof is effective to stimulate production in said subject mammal of antibodies that recognize a ZPB polypeptide of said subject mammal thereby inducing transient infertility.