Patent ID: 6335199
Filing Date: 2002-01-01
Classification: A61K,C12N

Abstract:
A lipid compound of formula:Raâ€”HNâ€”[â€”(CH2)m1â€”NRbâ€”]nâˆ’1â€”(CH2)m2â€”NHâ€”Rcâ€ƒâ€ƒI wherein:the Ra, Rb and Rc residues are, independently of each other, a hydrogen atom or a group of formula II: â€ƒwherein: R1 and R2 are, independently of each other, C6-C23 alkyl or alkenyl radicals, which are linear or branched, or radicals â€”C(&boxH;O)â€”(C6-C23) alkyl or â€”C(&boxH;O)â€”(C6-C23) alkenyl, which are linear or branched, aryl radicals, cycloalkyl radicals, fluoroalkyl radicals, polyethylene glycol groups, oxyethylene or oxymethylene groups, with the proviso that when either R1 or R2 is a polyethylene glycol group, an oxyethylene or an oxymethylene group, the other is a linear or branched C6-C23 alkyl or alkenyl radical, a linear or branched â€”C(&boxH;O)â€”(C6-C23) alkyl or â€”C(&boxH;O)â€”(C6-C23) alkenyl radical, an aryl radical, a cycloalkyl radical, a fluoroalkyl radical, p is a positive integer from 1 to 4, n is a positive integer from 1 to 6, m1 and m2 are a positive integer from 1 to 6, and m1 may be different for each motif â€”(CH2)m1â€”NRb, and wherein the total number of groups of formula II in said compound of formula I is between 1 and 4.