Patent ID: 8227407
Filing Date: 2012-07-24
Classification: A61P,C07D,C07K

Abstract:
1. A compound having the formula an N-oxide, salt, or stereoisomer thereof, wherein each dashed line (represented by - - - ) represents an optional double bond; X is N, CH and where X bears a double bond it is C; R L is a direct bond, —O—, —O—C R R R n is 3, 4, 5, or 6; p is 1 or 2; each R R R R R Het as a group or part of a group is a 5 or 6 membered saturated, partially unsaturated or completely unsaturated heterocyclic ring containing 1 to 4 heteroatoms each independently selected from nitrogen, oxygen and sulfur, being optionally condensed with a benzene ring, and wherein the group Het as a whole may be optionally substituted with one, two or three substituents each independently selected from the group consisting of halo, C