Patent ID: 6455257
Filing Date: 2002-09-24
Classification: C12N

Abstract:
Apparatus for making a designer disease comprising(A) first, second, and third containers, each having two sections, I and II, separated by a semipermeable material through which a microbe can pass but cells from target and non-target populations cannot pass, and an entrance and an exit to each section, where the entrance to section I of said first and second containers is a circulation entrance, the exit from section II of said first and second containers is a circulation exit, and the entrance to and exit from section I of said third container is a circulation entrance and a circulation exit, respectively; (B) conduits forming a loop by connecting the circulation exit of each container to the circulation entrance of another container; (C) a pump for moving fluid around said loop; and (D) means for mutating microbes in said fluid.