Patent ID: 8067209
Filing Date: 2011-11-29
Classification: C12Q

Abstract:
1. A method for screening an individual for having an increased risk of venous thrombosis, comprising determining the presence in the individual's genome of a genetic marker that is indicative of an increased risk of venous thrombosis, wherein the genetic marker is at least part of haplotype 2 of the fibrinogen γ gene (FGG-H2), wherein the presence of FGG-H2 is associated with the presence of a set of one, two, three or four mutations in the nucleic acid encoding fibrinogen γ, the mutations being selected from the group consisting of 129A/T (rs2066854), 7874G/A (rs2066861), 9615C/T (rs2066864) and 10034C/T (rs2066865).