Patent ID: 7099721
Filing Date: 2006-08-29
Classification: G05B,Y02P

Abstract:
1. A method for generating values for operating parameters for a multiple stage industrial or pilot scale bioprocess for obtaining a product from a biomaterial, said method comprising: (a) determining for at least one stage conditions which affect the properties of the material being processed; (b) simulating said conditions in at least one scale down experiment; (c) subjecting a test quantity of said biomaterial, or a derivative thereof, to the conditions simulated in said scale down experiment; (d) obtaining measurements of the effect of said simulated conditions on said test quantity of biomaterial or derivative; and (e) performing computer modelling utilising said measurements to obtain values for said operating parameters to achieve acceptable quality and yield of said product; wherein the step (d) of obtaining measurements of the effect of simulated conditions on a test quantity of biomaterial or derivative uses biomaterial or derivative similar in composition and physical properties to that which would be obtained in an industrial or pilot scale process.