Patent ID: 6392097
Filing Date: 2002-05-21
Classification: C07B,C07C

Abstract:
A process for the preparation of derivatives of octafluoro-[2,2]paracyclophane, which comprises the steps of:reacting octafluoro-[2,2]paracyclophane with a nitronium reagent to provide dinitro octafluoro-[2,2]paracylophane isomers; reducing said dinitro octafluoro-[2,2]paracylophane isomers by reacting the dinitro octafluoro-[2,2]paracyclophane isomers with iron powder in concentrated hydrochloric acid to provide pseudo-meta, pseudo-para and pseudo ortho isomers of diamino octafluoro-[2,2]paracyclophane in good yield; and reacting said diamino octafluoro-[2,2]paracylophane isomers with an aqueous halogen solution to provide pseudo-meta, pseudo-para and pseudo ortho isomers of hetero-annular dihalo-octafluoro- [2,2]paracylophane in good yield.