Patent ID: 7148220
Filing Date: 2006-12-12
Classification: A61P,C07D

Abstract:
1. A method for treating breast, ovarian, gastric and bladder cancer, comprising administering to a warm-blooded species in need thereof, a therapeutically effective amount of a compound of the formula wherein R is selected from the group consisting of aryl, substituted aryl, heterocyclo, and substituted heterocyclo; R 1 is selected from the group consisting of alkyl and substituted alkyl; R 2 is selected from the group consisting of hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, aralkyl, heterocyclo, and substituted heterocyclo; or, R 2 may be absent; X is selected from the group consisting of a bond, O, S, C(R 3 ) 2 , C(R 3 ) 3 , NR 3 ; and N(R 3 ) 2 ; R 3 is independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, aralkyl, heterocyclo, and substituted heterocyclo, or a pharmaceutically acceptable salt, enantiomer or diastereomer thereof.