Patent ID: 7361677
Filing Date: 2008-04-22
Classification: A61P,C07D

Abstract:
1. A compound of Formula IIId (i) wherein E is an optional linker group; R is a 5-, 6- or 7-membered carbocyclic ring; P is an optionally substituted 5- or 6-membered heterocyclic ring containing 1 to 3 hetero atoms selected from the group consisting of N, O and S; is a 5-, 6- or 7-membered ring; at least Q comprises a sulphamate group; and at least one of P, Q and R is substituted by one or more halo atoms; or, (ii) wherein E is an optional linker group; R is a 5-, 6- or 7-membered carbocyclic ring; P is an imidazole, tetrazole, or pyrazole; Q is a 5-, 6- or 7-membered ring; at least Q comprises a sulphamate group; and at least one of P, Q and R is optionally substituted by one or more halo atoms.