Patent ID: 9078731
Filing Date: 2015-07-14
Classification: A61F,A61L,D04B,D10B

Abstract:
1. A method for making a biocompatible, bioresorbable, implantable knitted silk mesh comprising: (a) applying a first set of silk yarns in a first wale direction on a single needle bed machine, the first set of silk yarns forming a first series of loops at each of a plurality of courses for the knitted silk mesh; (b) applying a second set of silk yarns in a second wale direction on the single needle bed machine, the second wale direction being opposite from the first wale direction, the second set of silk yarns forming a second series of loops at every other of the plurality of courses for the knitted silk mesh; (c) applying a third set of silk yarns in every predetermined number of courses for the knitted silk mesh, the application of the third set of silk yarns defining openings in the knitted silk mesh; and (d) depleting sericin from the first, second and third sets of silk yarns or from the knitted silk mesh before the knitted silk mesh is implanted, wherein the first set of the silk yarns interlaces with the second set of the silk yarns at the every other course to define nodes for the knitted silk mesh, and the second set of the silk yarns has a greater tension than the first set of the silk yarns, the difference in tension substantially preventing the knitted silk mesh from unraveling at the nodes, thereby making the biocompatible, bioresorbable, implantable, knitted silk mesh.