Patent ID: 9089267
Filing Date: 2015-07-28
Classification: A61B,A61N

Abstract:
1. A method for delivering neurostimulation to a body having a vagus nerve and a laryngeal muscle, the vagus nerve including A-fibers and B-fibers, the A-fibers primarily responsible for activation of the laryngeal muscle, the B-fibers primarily responsible for modulating a cardiovascular function, the method comprising: delivering neurostimulation pulses to the vagus nerve; controlling the delivery of the neurostimulation pulses using a stimulation intensity; sweeping levels of the stimulation intensity at specified increments; sensing a physiological signal indicative of evoked responses each including an activation of the A-fibers evoked by one of the neurostimulation pulses; detecting the evoked responses by comparing the physiological signal to one or more detection thresholds; determining a first stimulation threshold being a minimum level of the stimulation intensity for activating the A-fibers; calculating a level of the stimulation intensity for modulating the cardiovascular function by the delivery of the neurostimulation pulses using the first stimulation threshold and a predetermined relationship between the first stimulation threshold and a second stimulation threshold being a minimum level of the stimulation intensity for activating the B-fibers; and adjusting the stimulation intensity to the calculated level.