Patent ID: 6693101
Filing Date: 2004-02-17
Classification: A61K,A61P,C07D

Abstract:
A compound selected from the group consisting of:3-(5-3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazin-6-yl-pentanoylamino)-3-(quinolin-3-yl)-propionic acid; 3-(5-3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazin-6-yl-pentanoylamino)-3(R)-(quinolin-3-yl)-propionic acid; 3-(5-3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazin-6-yl-pentanoylamino)-3(S)-(quinolin-3-yl)-propionic acid; 3-(Quinolin-3-yl)-3-(5-1,2,3,4-tetrahydro-pyrido[2,3-b]pyrazin-6-yl-pentanoylamino)-propionic acid; 3(R)-(Quinolin-3-yl)-3-(5-1,2,3,4-tetrahydro-pyrido[2,3-b]pyrazin-6-yl-pentanoylamino)-propionic acid; 3(S)-(Quinolin-3-yl)-3-(5-1,2,3,4-tetrahydro-pyrido[2,3-b]pyrazin-6-yl-pentanoylamino)-propionic acid; 9-(6-Methylamino-pyridin-2-yl)-3-(pyrimidin-5-yl)-nonanoic acid; 9-(6-Methylamino-pyridin-2-yl)-3(R)-(pyrimidin-5-yl)-nonanoic acid; 9-(6-Methylamino-pyridin-2-yl)-3(S)-(pyrimidin-5-yl)-nonanoic acid; 9-(6-Methylamino-pyridin-2-yl)-3-(2-methyl-pyrimidin-5-yl)-nonanoic acid; 9-(6-Methylamino-pyridin-2-yl)-3(R)-(2-methyl-pyrimidin-5-yl)-nonanoic acid; 9-(6-Methylamino-pyridin-2-yl)-3(S)-(2-methyl-pyrimidin-5-yl)-nonanoic acid; 3-(2-Methoxy-pyrimidin-5-yl)-9-(6-methylamino-pyridin-2-yl)-nonanoic acid; 3(R)-(2-Methoxy-pyrimidin-5-yl)-9-(6-methylamino-pyridin-2-yl)-nonanoic acid; 3(S)-(2-Methoxy-pyrimidin-5-yl)-9-(6-methylamino-pyridin-2-yl)-nonanoic acid; 3-(2-Ethoxy-pyrimidin-5-yl)-9-(6-methylamino-pyridin-2-yl)-nonanoic acid; 3(R)-(2-Ethoxy-pyrimidin-5-yl)-9-(6-methylamino-pyridin-2-yl)-nonanoic acid; 3(S)-(2-Ethoxy-pyrimidin-5-yl)-9-(6-methylamino-pyridin-2yl)-nonanoic acid; 9-(6-Ethylamino-pyridin-2-yl)-3-(2-methyl-pyrimidin-5-yl)-nonanoic acid; 9-(6-Ethylamino-pyridin-2-yl)-3(R)-(2-methyl-pyrimidin-5-yl)-nonanoic acid; 9-(6-Ethylamino-pyridin-2-yl)-3(S)-(2-methyl-pyrimidin-5-yl)-nonanoic acid; 3-(2-Methoxy-pyrimidin-5-yl)-9-(6-ethylamino-pyridin-2-yl)-nonanoic acid; 3(R)-(2-Methoxy-pyrimidin-5-yl)-9-(6-ethylamino-pyridin-2-yl)-nonanoic acid; 3(S)-(2-Methoxy-pyrimidin-5-yl)-9-(6-ethylamino-pyridin-2-yl)-nonanoic acid; 3-(2-Ethoxy-pyrimidin-5-yl)-9-(6-ethylamino-pyridin-2-yl)-nonanoic acid; 3(R)-(2-Ethoxy-pyrimidin-5-yl)-9-(6-ethylamino-pyridin-2-yl)-nonanoic acid; 3(S)-(2-Ethoxy-pyrimidin-5-yl)-9-(6-ethylamino-pyridin-2-yl)-nonanoic acid; 3-9-(6-Methylamino-pyridin-2-yl)-3-quinoxalin-2-yl)-nonanoic acid; 3(R)-9-(6-Methylamino-pyridin-2-yl)-3-quinoxalin-2-yl)-nonanoic acid; 3(S)-9-(6-Methylamino-pyridin-2-yl)-3-quinoxalin-2-yl)-nonanoic acid; 3-9-(2,3Dihydro-1H-pyrrolo[2,3-b]pyridin-6-yl)-3-(2-methyl-pyrimidin-5-yl)-nonanoic acid; 3-(R)-9-(2,3Dihydro-1H-pyrrolo[2,3-b]pyridin-6-yl)-3-(2-methyl-pyrimidin-5-yl)-nonanoic acid; and 3(S)-9-(2,3Dihydro-1H-pyrrolo[2,3-b]pyridin-6-yl)-3-(2-methyl-pyrimidin-5-yl)-nonanoic acid; or a pharmaceutically acceptable salt thereof.