Patent ID: 8222238
Filing Date: 2012-07-17
Classification: A61K,A61P,C07D

Abstract:
1. A method of treating a subject having an increased intracranial pressure, comprising administering to the subject a therapeutically sufficient amount of a compound of the general formula (Ia) wherein in formula (Ia) R 1 , R 3 are independently selected from H or OH, R 4 is H, CH 3 , CH 2 OH; CHO, R 2 is H, CH 3 , CH 2 OH, CHO or a lower C 1 -C 9 alkyl radical, which can be a straight or a branched chain, as well as (CH(OH)) n —Y or (CH(OH)) n —(CH 2 ) m —W, wherein Y is hydrogen or a lower alkyl radical, W is hydrogen or a hydroxyl group, an n and m are independently from each other 1-20, wherein the increased intracranial pressure is caused by closed craniocerebral trauma.