Patent ID: 7192947
Filing Date: 2007-03-20
Classification: A61K,A61P,C07K

Abstract:
1. A compound of formula (I): wherein: R R R R R or a pharmaceutically acceptable salt, solvate or solvate of such a salt, or an in vivo hydrolysable ester formed on an available carboxy or hydroxy thereof, or an in vivo hydrolysable amide formed on an available carboxy thereof; with the proviso that when R 1 and R 2 are both butyl, R 5 is hydroxy and R 4 is methylthiomethyl, methylsulphinylmethyl, 2-methylthioethyl, hydroxymethyl, methoxymethyl; R 3 is not hydrogen; and with the proviso that when R 1 and R 2 are both butyl, R 5 is HOC(O)CH(R 6 )NH—, R 6 is hydroxymethyl and R 4 is hydroxymethyl; R 3 is not hydrogen.