Patent ID: 8354125
Filing Date: 2013-01-15
Classification: A61K,A61P

Abstract:
1. A method of ex vivo treatment of mononuclear cells, comprising the steps of: (a) obtaining peripheral blood from a human subject; (b) isolating mononuclear cells from said peripheral blood; (c) exposing said isolated mononuclear cells to interferon lambda (IFN-λ); and (d) administering said exposed cells to said human subject, wherein said IFN-λ is present in an amount sufficient to inhibit a stimulus-induced cytokine release, and wherein said stimulus is selected from the group consisting of Concanavalin A and anti-CD2/3/28 beads and said cytokine is at least one compound selected from the group consisting of interleukin-4 (IL-4) and interleukin-5 (IL-5).