Patent ID: 7570443
Filing Date: 2009-08-04
Classification: B01L,G01N

Abstract:
1. A method of aligning a sequence detection system comprising: providing a light source in the expected location of a well of a high density well plate; providing a collection camera defining a camera image plane, said collection camera being mounted to a camera mounting plate, said collection camera operable to detect said light source; providing a lens having an optical assembly defining a lens image plane, said lens being mounted to a base plate; actuating a planarity adjustment mechanism operably coupled to at least one of said camera mounting plate and said base plate to rotate an axis normal to said camera image plane relative to an axis normal to said lens image plane; and actuating a concentricity adjustment mechanism operably coupled to one of said camera mounting plate and said base plate to translate an axis normal to said camera image plane with respect to an axis normal to said lens image plane.