Patent ID: 7829063
Filing Date: 2010-11-09
Classification: A61P,C07D,C12Q,G01N

Abstract:
1. A compound consisting of the Formula Ia or Ib: wherein for Ia and Ib: each G is independently a bond or is independently selected from the group consisting of cycloalkyl, aryl-CH(Y)—, heterocyclyl, aryl and heteroaryl, wherein said cycloalkyl, aryl-CH(Y)—, heterocyclyl, aryl and heteroaryl are substituted or unsubstituted; n is 0, 1, 2 or 3; X is a bond, or is selected from the group consisting of —O—, —S—, —S(O)—, —S(O) X′ is selected from the group consisting of a quaternary ammonium salt, imidate salt, thiolate salt, oxonium cation, boron-amine salt, pyridinium salt, —SO Y is H or is selected from the group consisting of a quaternary ammonium salt, imidate salt, thiolate salt, oxonium cation, boron-amine salt, pyridinium salt, —SO R is H or a side chain of an encoded amino acid, halobenzyl, —C Z is —CH wherein at least one of the group X, X′, G, X and Y optionally comprises a radionuclide; or a pharmaceutically acceptable salt thereof, optionally in the form of a single stereoisomer or mixtures of stereoisomers thereof.