Patent ID: 8093369
Filing Date: 2012-01-10
Classification: A61K,C12N

Abstract:
1. An RNA interference (RNAi) molecule wherein the RNAi molecule comprises: a. a first ribo-oligonucleotide sequence having the nucleic acid sequence set forth in SEQ ID NO:6; and b. a second ribo-oligonucleotide sequence having the nucleic acid sequence set forth in SEQ ID NO:7; wherein said first ribo-oligonucleotide sequence and said second ribo-oligonucleotide sequence anneal to each other to form said RNAi molecule and wherein the RNAi molecule silences mitochondrial human voltage-dependent anion channel 1 (VDAC1) expression and the RNAi molecule inhibits T-REx-293 cell proliferation when an effective amount of said RNAi molecule is delivered to T-Rex-293 cell.