Patent ID: 6610748
Filing Date: 2003-08-26
Classification: A61K,A61P

Abstract:
A method for treatment of dermal aging comprising:selecting a subject in need of treatment of dermal aging and externally administering to said subject a composition comprising a trifluoromethylketone derivative of the following formula or a pharmaceutically acceptable salt thereof: â€ƒwherein: R1 represents a lower alkyl group having 1 or 2 substituents selected from the group consisting of carboxy, esterified carboxy and di-lower alkylcarbamoyl; a phenyl(lower)alkyl group that may optionally have halogen, amino or nitro on the phenyl moiety thereof and carboxy or esterified carboxy on the alkyl moiety thereof; a halophenyl group; a morpholino group; or a morpholino (lower) alkyl group; R2 and R3 each independently represent a lower alkyl group; X is either â€” or â€”NHâ€”; and â€ƒin a form and in an amount suitable for treating dermal aging.