Patent ID: 6113941
Filing Date: 2000-09-05
Classification: A61K,Y10S

Abstract:
A sustained release pharmaceutical microcapsule comprising:a basic physiologically active compound which is soluble in 20.degree. water at a pH of about 3 or less but not more than about 0.01 g of said compound is soluble in 100 ml of 20.degree. C. water at pH to 8, wherein said basic physiologically active compound comprises a moiety selected from the group consisting of imidazole, benzimidazole, triazole and alanylglycine, anda polymer having a weight-average molecular weight in the range of about 2,000 to about 8,000, said polymer being biodegradable in the digestive tract of a mammal from the duodenum to the rectum upon oral administration.