Patent ID: 7579500
Filing Date: 2009-08-25
Classification: C07C,C07D

Abstract:
1. A method for preparing 2,5-dimethyiphenylacetic acid, characterized in that p-xylene is converted with chloroacetyl chloride in a Friedel-Crafts reaction into 2-chloro-1-(2,5-dimethylphenyl)ethanone, which is reacted with the compound of the formula (II) in which X is a direct single bond or selected from the group consisting of CH to give the compound of the formula (III) in which X has the meaning indicated above; the compound of the formula (III) is then rearranged to give a mixture of the formulae (IV) and (V) in which X has the meanings indicated above, and the latter is then hydrolyzed to 2,5-dimethylphenylacetic acid.