Patent ID: 7495010
Filing Date: 2009-02-24
Classification: A61P,C07D

Abstract:
1. A method of inhibiting the binding of acetylcholine to an acetylcholine receptor in a mammal in need thereof, comprising contacting the acetylcholine receptor with an effective amount of a composition comprising a compound of Formula (I) wherein: R2 and R3 are, independently, selected from the group consisting of straight or branched chain lower alkyl groups (having 1 to 6 carbon atoms), cycloalkyl groups (having from 5 to 6 carbon atoms), cycloalkyl-alkyl (having 6 to 10 carbon atoms), 2-thienyl, 2-pyridyl, phenyl, phenyl substituted with an alkyl group having not in excess of 4 carbon atoms and phenyl substituted with an alkoxy group having not in excess of 4 carbon atoms; and X such that the compound is a quaternary salt; and a pharmaceutically acceptable carrier or diluent suitable for dry powder oral inhalation; and wherein the method of contacting the receptor with the composition is via inhalation by the mouth of the mammal.