Patent ID: 6255326
Filing Date: 2001-07-03
Classification: C07C,C07D

Abstract:
A compound of formula I ##STR36##whereinR.sup.1 is optionally substituted lower alkyl;R.sup.2 is optionally halo substituted C.sub.3 -C.sub.15 alkyl, optionally substituted alkenyl, or alkyl substituted by cycloalkyl or cycloalkenyl and further optionally substituted by halo;R.sup.3 is optionally substituted heteroaryl or optionally substituted aryl wherein said aryl is phenyl or naphthyl, either of which may be substituted with one or more aryl group substituents which may be the same or different, selected from the group consisting of hydrogen, alkyl, aryl, aralkyl, hydroxy, hydroxyalkyl, alkoxy, aryloxy, aralkoxy, carboxy, acyl, aroyl, halo, nitro, cyano, carboxy, alkoxycarbonyl, aryloxycarbonyl, aralkoxycarbonyl, acylamino, aroylamino, alkylsulfonyl, arylsulfonyl, alkylsulfinyl, arylsulfinyl, alkylthio, arylthio, aralkylthio, Y.sup.1 Y.sup.2 N--, Y.sup.1 Y.sup.2 NCO-- or Y.sup.1 Y.sup.2 NSO.sub.2 --, where Y.sup.1 and Y.sup.2 are independently selected from the group consisting of hydrogen, alkyl, aryl, and aralkyl;Z, Z.sup.1 and Z.sup.2 are independently oxygen or sulfur; andZ.sup.3 is --CZNH--, oran N-oxide thereof or a pharmaceutically acceptable salt thereof.