Patent ID: 6444646
Filing Date: 2002-09-03
Classification: A61K,A61P

Abstract:
A method of accelerating wound healing, comprising applying to a wound an amount effective to accelerate wound healing of an active agents, wherein the active agent comprises a sequence of the formulaR1â€”R2â€”R3â€”R4â€”R5â€”R6â€”R7â€”R8 wherein R1 is selected from the group consisting of Asp, Glu, Asn. Acpc, Ala, Me2Gly, Pro, Bet, Glu(NH2), Gly, Asp(NH2), and Suc; R2 is selected from the group consisting of Arg, Lys, Ala, Orn Ser(Ac), Sar, D-Arg, and D-Lys; R3 is selected from the group consisting of Val, Ala, Leu, Ile, Gly, Pro, Aib, Acpc, and Tyr; R4 is selected from the group consisting of Tyr, Thr, Ser, and azaTyr; R5 is selected from the group consisting of Ile, Ala, Leu, Val, and Gly; R6 is p-NH2-Phe; R7 is Pro or Ala; R8 is selected from the group consisting of Phe, Phe(Br), Ile, and Tyr; and wherein the active agent is not AII.