Patent ID: 7112594
Filing Date: 2006-09-26
Classification: A61K,A61P,C07D

Abstract:
1. A fused bicyclic amide compound represented by the formula (I) wherein R R ring A is benzene or cyclohexane, represented by one of the following formulas: ring B is pyrrole or a derivative thereof, furan or thiophene, represented by one of the following formulas:  wherein R W is hydrogen, alkyl or hydroxycarbonylalkyl; X is cyano; X′ is hydrogen; and Y is piperidine having at least one substituent selected from the group consisting of hydroxy; carboxy; alkoxycarbonyl; hydroxyalkyl; alkoxyalkoxy; carboxyalkylcarbonyloxy; acyloxy; benzoyloxy; phenyl; alkylenedioxy; oxo; amino optionally mono- or di- substituted by alkoxyalkyl; cyclic amine selected from piperidine optionally having substituent, morpholine, thiomorpholine, and piperazine optionally having substituent (wherein the cyclic amine may be N-oxide); and morpholinomethyl; or a pharmaceutically acceptable salt thereof.