Patent ID: 6262105
Filing Date: 2001-07-17
Classification: A61K,A61P,A61Q,Y10S

Abstract:
A method for stimulating hair growth in a mammalian species comprising the application to mammalian skin of an effective amount of a prostaglandin PGF compound wherein the alpha chain of the compound has the formula: ##STR36##in which R.sub.1 is H or an alkyl group having from 1 to 10 carbon atoms; andthe omega chain of the compound has the formula:C--B--C--D--R.sub.2wherein C is a carbon atom or lower alkyl chain, optionally substituted with one or more --OH groups;B is a single bond, a double bond or a triple bond;D is a chain having from 1 to 10 carbon atoms, optionally substituted with one or more --OH groups; andR.sub.2 is H; a phenyl group having none, one or more substituents selected from the group consisting of C.sub.1 -C.sub.5 alkyl groups, C.sub.1 -C.sub.5 haloalkyl groups, C.sub.1 -C.sub.4 alkoxy groups, C.sub.1 -C.sub.4 haloalkoxy groups, trifluoromethyl groups, C.sub.1 -C.sub.3 aliphatic acylamino groups, nitro groups, halogen atoms, and phenyl groups; an aromatic heterocyclic group having 5-6 ring atoms; or a cycloalkane or a cycloalkene with 3-7 carbon atoms in the ring, optionally substituted with lower alkyl groups with 1-5 carbon atoms;or a pharmacologically acceptable acid addition salt thereof.