Patent ID: 9034856
Filing Date: 2015-05-19
Classification: A61P,C07J

Abstract:
1. The 17-(1′-Propenyl)-17-3′-oxidoestra-4-en-3-one derivative selected from the group comprising of: 7α-Methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 7β-Methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 7α-Ethyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 7β-Ethyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 7α-Vinyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 7β-Vinyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 7α-Cyclopropyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 7β-Cyclopropyl-17α-(1-propenyl)-17β-3′-oxidoestra-4-en-3-one; 6-Methylene-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 6α-Hydroxymethylene-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 6β-Hydroxymethylene-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 6,6-(1,2-Ethanediyl)-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 6α,7α-Methylene-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 6β,7β-Methylene-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 17α-(1′-Propenyl)-17β-3′-oxidoestra-4,6-dien-3-one; 16,16-(1,2-Ethanediyl)-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; (E/Z)-3-(Hydroxyimino)-7α-methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-7β-methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-7α-ethyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-7β-ethyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-7α-vinyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-7β-vinyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-7α-cyclopropyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-7β-cyclopropyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-6-methylene-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-6α-hydroxymethylene-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-6β-hydroxymethylene-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-6,6-(1,2-ethanediyl)-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-6α,7α-methylene-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-6β,7β-methylene-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-17α-(1′-propenyl)-17β-3′-oxidoestra-4,6-diene; (E/Z)-3-(Hydroxyimino)-16,16-(1,2-ethanediyl)-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; 7 α,18-Dimethyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 7 β,18-Dimethyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 7β-Ethyl-18-methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 7α-Vinyl-18-methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 7β-Vinyl-18-methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 7α-Cyclopropyl-18-methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 7β-Cyclopropyl-18-methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-en-3-one; 6-Methylene-17α-(1′-propenyl)-18-methyl-17β-3′-oxidoestra-4-en-3-one; 6α-Hydroxymethylene-17α-(1′-propenyl)-18-methyl-17β-3′-oxidoestra-4-en-3-one; 6,6-(1,2-Ethanediyl)-17α-(1′-propenyl)-18-methyl-17β-3′-oxidoestra-4-en-3-one; 6α,7α-Methylene-17α-(1′-propenyl)-18-methyl-17β-3′-oxidoestra-4-en-3-one; 6β,7β-Methylene-17α-(1′-propenyl)-18-methyl-17β-3′-oxidoestra-4-en-3-one; 17α-(1′-Propenyl)-18-methyl-17β-3′-oxidoestra-4,6-dien-3-one; 16,16-(1,2-Ethanediyl)-17α-(1′-propenyl)-18-methyl-17β-3′-oxidoestra-4-en-3-one; (E/Z)-3-(Hydroxyimino)-18-methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-7α,18-dimethyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-7β,18-dimethyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-7α-ethyl-18-methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-7β-ethyl-18-methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-7α-vinyl-18-methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-7β-vinyl-18-methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-7α-cyclopropyl-18-methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-7β-cyclopropyl-18-methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-6-methylene-17α-(1′-propenyl)-18-methyl-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-6α-hydroxymethylene-17α-(1′-propenyl)-18-methyl-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-6β-hydroxymethylene-17α-(1-propenyl)-18-methyl-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-6,6-(1,2-ethanediyl)-17α-(1′-propenyl)-18-methyl-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-6α,7α-methylene-17α-(1′-propenyl)-18-methyl-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-6β,7β-methylene-17α-(1′-propenyl)-18-methyl-17β-3′-oxidoestra-4-ene; (E/Z)-3-(Hydroxyimino)-18-methyl-17α-(1′-propenyl)-17β-3′-oxidoestra-4,6-diene; and (E/Z)-3-(Hydroxyimino)-16,16-(1,2-ethanediyl)-17α-(1′-propenyl)-18-methyl-17β-3′-oxidoestra-4-ene.