Patent ID: 6596885
Filing Date: 2003-07-22
Classification: A61P,C07J

Abstract:
A compound of formula wherein R17a and Râ€²17a taken together form a member of the group consisting of a ketone, an oxime, hydrazono and methylene or R17a is selected from the group consisting of protected â€”OH, protected hydroxymethyl and acyloxy of up to 12 carbon atoms, and Râ€²17a is selected from the group consisting of hydrogen and alkyl, alkenyl and alkynyl of up to 8 carbon atoms, each optionally substituted,X is selected from the group consisting of methylene, arylene and arylenoxy group having at most 10 carbon atoms linked to the steroid by a carbon atom, Y is saturated or unsaturated, aliphatic of 1 to 18 carbon atoms, optionally interrupted by an oxygen atoms, Râ€²3 is hydrogen or a hydroxy protective group, and W is hydrogen or â€”COR with R being alkyl of 1 to 5 carbon atoms.