Patent ID: 6379301
Filing Date: 2002-04-30
Classification: A61B,G01N,G09B,G16H,Y10S

Abstract:
An apparatus for assisting a patient having diabetes mellitus in controlling blood glucose, said apparatus comprising:a) an input means for entering a blood glucose value G(td) representative of a blood glucose concentration of the patient at time td and for entering an insulin dose value Ik representative of an insulin dose administered to the patient prior to time td; b) a memory means for storing an insulin sensitivity value representative of an insulin sensitivity of the patient and for storing information for determining an insulin action value Fk(2d) representative of a fraction of insulin action remaining at time td from said insulin dose; c) a processor connected to said input means and said memory means for determining said insulin action value Fk(td) and for determining a future blood glucose value G(tj) representative of an expected blood glucose concentration of the patient at time tj, wherein said processor determines said future blood glucose value G(tj) in dependence upon said blood glucose value G(td), said insulin dose value Ik, said insulin sensitivity value, and said insulin action value Fk(td); d) an interpolation formula to calculate the insulin action value Fk(td) programmed into the processor, the formula to calculate the insulin action value comprising Fk(td)=Y0+((Zkâˆ’X0)(Y1âˆ’Y0)/(X1âˆ’X0)) wherein X0 represents an initial insulin dose, Y0 represents an insulin action value at initial dose X0, X1 represents a following insulin dose, Y1 represents an insulin action value at following insulin dose X1, and Zk represents time after injection of insulin dose Ik at time td;e) a formula to calculate the future blood glucose value G(tj) programmed into the processor, the formula to calculate the food glucose value comprising: G&af;(tâ€ƒ&it;j)=G&af;(td)-S&af;[&Sum;k=1N&it;Ik&it;Fk&af;(td)-Fk&af;(tj)]wherein S represents insulin sensitivity values, Ik represents insulin dose values administered prior to time td, and Fk(tj) represents insulin action values at time (tj), k=1 represents a single insulin bolus dose and a supplemental insulin bolus dose, and N represents the total number of insulin bolus doses and supplemental insulin bolus doses; andf) a display means connected to said processor for displaying said future blood glucose value G(tj), thereby enabling the patient to take timely corrective action to prevent hypoglycemia or hyperglycemia.