Patent ID: 7304072
Filing Date: 2007-12-04
Classification: A61P,C07D

Abstract:
1. A compound represented by the general formula (I-b): wherein Ar 1 represents phenyl, pyrrolyl, imidazolyl, pyrazolyl, thiazolyl, oxazolyl, isoxyazolyl, 1,2,3-triazolyl, 1,2,4-thiadiazolyl, pyridyl, pyrazinyl, pyrimidinyl, 1,2, 4-triazinyl, benzoxazolyl, benzothiazolyl, quinolyl or pyrido [3,2-b]pyridyl which may be substituted, the substituent being selected from the group consisting of hydroxy, halogen, nitro, lower alkyl, halo(lower)alkyl, hydroxy(lower)alkyl, cyclo(lower)alkyl, lower alkenyl, lower alkoxy, halo(lower)alkoxy, lower alkylthio, carboxyl, lower alkanoyl, lower alkoxycarbonyl, lower alkylene optionally substituted with oxo, and a group represented by the formula -Q-Ar 2 ; Ar Q represents a single bond or carbonyl; R T, U, V and W each independently represent a nitrogen atom or a methine group which may have a substituent selected from the group consisting of halogen, lower alkyl, hydroxy and lower alkoxy, wherein at least two of which represent said methine group or a salt, ester of a carboxyl group or N-oxide derivative thereof, with the proviso that if the compound is not an N-oxide derivative, Ar