Patent ID: 6485695
Filing Date: 2002-11-26
Classification: G21G

Abstract:
A method for preparing Bi-213 to be integrated in a radioimmunoconjugate for human therapeutic use, comprising a sequence of steps as follows:a) an ampoule containing colloid-free actinium-225, obtained from drying and heating an actinium nitrate solution, is loaded into a container provided with radiation panels; (b) a dissolving medium is poured into the ampoule to obtain a solution; (c) the solution obtained in the ampoule is transferred into an ion exchange column; (d) an elution medium is circulated continuously through the ion exchange column; and (e) at regular intervals an eluate containing eluted Bi-213, which grows by decay of Ac-225, is pumped towards a vial for quantification and quality control.