Patent ID: 7244723
Filing Date: 2007-07-17
Classification: A61P,C07D

Abstract:
1. A compound of Formula I: or a pharmaceutically acceptable salt or stereoisomer thereof, wherein: one of W, Y and Z is O and the other two of W, Y and Z are CH; a is 0 or 1; b is 0 or 1; m is 0, 1, or 2; n is 0 to 2; u is 2, 3, 4 or 5; R said alkyl, aryl, alkenyl, alkynyl, cycloalkyl, aralkyl and heterocyclyl is optionally substituted with one or more substituents selected from R R said alkyl, aryl, alkenyl, alkynyl, cycloalkyl, and heterocyclyl is optionally substituted with one or more substituents selected from R R R said alkyl, aryl, alkenyl, alkynyl, cycloalkyl, and heterocyclyl is optionally substituted with one or more substituents selected from R or R which is a 5–12 membered nitrogen-containing heterocycle, which is optionally substituted with from one to six R 5 groups and which optionally incoporates from one to two additional heteroatoms, selected from N, O and S in the heterocycle ring; R said alkyl, aryl, alkenyl, alkynyl, cycloalkyl, and heterocyclyl is optionally substituted with one or more substituents selected from R R said alkyl, aryl, alkenyl, alkynyl, heterocyclyl, and cycloalkyl optionally substituted with one or more substituents selected from R R said alkyl, alkenyl, alkynyl, cycloalkyl, aryl, and heterocyclyl is optionally substituted with up to three substituents selected from R R said alkyl, cycloalkyl, aryl, heterocylyl, alkenyl, and alkynyl is optionally substituted with one or more substituents selected from R R R R