Patent ID: 6699909
Filing Date: 2004-03-02
Classification: C07C,C07D

Abstract:
A compound having structural formula (I): or stereoisomers, pharmaceutically acceptable salts, or hydrates thereof, wherein:R1 and R2 are independently: H, or an acidic group selected from the group consisting of carboxy and â€”(CH2)n-carboxy, where n=1, 2, 3, 4, 5, or 6; X is an acidic carboxy group; Y is a basic group selected from the group consisting of aliphatic 1Â° amino, aliphatic 2Â° amino, aliphatic 3Â° amino, aliphatic quaternary ammonium salts, aromatic 1Â° amino, aromatic 2Â° amino, aromatic 3Â° amino, and aromatic quaternary ammonium salts; m is 0 or 1; and R3, R4, R5, and R6 are independently selected from the group consisting of H, nitro, amino, halogen, trifluoromethyl, trifluoroacetyl, sulfo, carboxy, carbamoyl, and sulfamoyl, or pharmaceutically acceptable salt thereof; with the proviso thatat least one of R1 and R2 is carboxy or â€”(CH2)n, carboxy.