Patent ID: 6399662
Filing Date: 2002-06-04
Classification: A61K,Y10S

Abstract:
A method of treating diarrhea or gastrointestinal spasm in a human or non-human animal in need thereof comprising administering to said animal an effective amount of a compound having the formula:R1N1(R2)â€”(CH2)xâ€”N2Hâ€”Qâ€”N3Hâ€”(CH2)yâ€”N4(R3)â€”R4â€ƒâ€ƒ(I) wherein: R1, R2, R3 and R4 are the same or different and are H, alkyl, cycloalkyl or aralkyl having from 1 to 12 carbon atoms, or R1 and R2 and/or R3 and R4 form a heterocyclic group having from 3 to 10 atoms wherein the hetero atom is said N1 or N4;Q is a cycloalkyl group having from 3 to 10 carbon atoms; x is an integer from 3 to 6, inclusive; and y is an integer from 3 to 6, inclusive; or (II) a salt thereof with a pharmaceutically acceptable acid.