Patent ID: 7977336
Filing Date: 2011-07-12
Classification: A61P,C07D

Abstract:
1. A compound of Formula [I]: or a pharmaceutically acceptable salt or ester thereof wherein: R one of R a) a lower alkyl group substituted with NR b) a 4 -to 6-membered aliphatic heterocyclic group selected from an azetidinyl group, a pyrrolidinyl group, a piperidinyl group, and a piperazinyl group; or c) a lower alkyl group substituted with a 4- to 6-membered aliphatic heterocyclic group selected from an azetidinyl group, a pyrrolidinyl group, a piperidinyl group, and a piperazinyl group, wherein the aliphatic heterocyclic group may be substituted with one or more substituents, which may be the same or different, selected from the following 1) to 4): R <Substituent Group α> and <Substituent Group β> are defined as below: <Substituent Group α>: a halogen atom, a hydroxy group, a nitro group, a cyano group, an amino group, a carbamoyl group, an aminosulfonyl group, an imino group, a lower alkylamino group, a di-lower alkylamino group, a lower alkylsulfonyl group, a lower alkylsulfonylamino group, a lower alkoxy group, a lower alkoxycarbonyl group, a lower alkoxycarbonylamino group, a lower alkanoyl group, a lower alkanoyloxy group, a lower alkylthio group, and a carboxyl group; and <Substituent Group β>: a halogen atom, a hydroxy group, a nitro group, a cyano group, an amino group, a carbamoyl group, an aminosulfonyl group, an imino group, a lower alkylsulfonyl group, a lower alkylsulfonylamino group, a lower alkoxy group, a lower alkoxycarbonyl group, a lower alkoxycarbonylamino group, a lower alkanoyl group, a lower alkanoyloxy group, a lower alkylthio group, a carboxyl group, and a benzyl group.