Patent ID: 6288243
Filing Date: 2001-09-11
Classification: C07F

Abstract:
A process for separating L-ascorbyl 2-monophosphate from a desalted mixture obtained from phosphorylation of an L-ascorbic acid salt under basic conditions comprising:(a) contacting an aqueous solution of the desalted mixture containing L-ascorbyl 2-monophosphate with a basic anion exchange resin in a separation vessel, wherein the L-ascorbyl 2-monophosphate is adsorbed to the resin;(b) eluting the L-ascorbyl 2-monophosphate from the resin with an aqueous alkali hydroxide solution; and(c) isolating the L-ascorbyl 2-monophosphate in a corresponding mono-alkali metal salt form from a fraction of the eluate which contains the L-ascorbyl 2-monophosphate in a corresponding mono-alkali metal salt form.