Patent ID: 8486890
Filing Date: 2013-07-16
Classification: A61K,A61P,C07K

Abstract:
1. A derivative of human amylin or an analog thereof, wherein a) an amino acid residue in position 2 to 37 has been substituted with a lysine residue or a cysteine residue and wherein said lysine residue or cysteine residue is linked to an albumin binding residue via a linker, or b) the lysine residue in position 1 is linked to an albumin binding residue via a linker, or a lysine residue has been added in position 38 and wherein said lysine residue is linked to an albumin binding residue via a linker; wherein the combined albumin binding residue and linker is wherein Z is CH wherein the amino acid numbering conforms with the amino acid numbering in SEQ ID No 1.