Patent ID: 7622611
Filing Date: 2009-11-24
Classification: A61P,C07C

Abstract:
1. A compound of formula I wherein R1 is hydrogen, alkyl having 1, 2, 3 or 4 carbon atoms, alkoxy having 1, 2, 3 or 4 carbon atoms, F, Cl, Br, I, —CN, NR5R6, —O p —(CH 2 ) n —(CF 2 ) o —CF 3 or —(SO m ) q —(CH 2 ) r —(CF 2 ) s —CF 3 ; R5 and R6 are, independently of one another, hydrogen, alkyl having 1, 2, 3 or 4 carbon atoms or —CH m is zero, 1 or 2; n, o, p, q, r and s are, independently of one another, zero or 1; R2 is hydrogen, alkyl having 1, 2, 3 or 4 carbon atoms, alkoxy having 1, 2, 3 or 4 carbon atoms, F, Cl, Br, I, —CN, NR7R8, —O R7 and R8 are, independently of one another, hydrogen, alkyl having 1, 2, 3 or 4 carbon atoms, or —CH w is zero, 1 or 2; t, u, v, x, y and z are, independently of one another, zero or 1; R3 is Cl, Br, I, —CN, —SO R9 and R10 are, independently of one another, hydrogen, alkyl having 1, 2, 3 or 4 carbon atoms, or —CH a, b and c are, independently of one another, zero or 1; d is zero, 1 or 2; e is zero or 1; f is zero, 1, 2, 3 or 4; g is zero or 1; or R3 is —(CH j is zero or 1; k is zero, 1, 2 or 3; h is zero, 1, 2, 3 or 4; or R3 is —(CH bb is zero or 1; cc is zero or 1, 2 or 3; aa is zero, 1, 2, 3 or 4; R4 is hydrogen, F, Cl, Br, I, —CN, —SO R11 and R12 are, independently of one another, hydrogen, alkyl having 1, 2, 3 or 4 carbon atoms or —CH2—CF3; dd, ee and ff are, independently of one another, zero or 1; gg is zero, 1 or 2; hh is zero or 1; jj is zero, 1, 2, 3 or 4; kk is zero or 1; or R4 is —(CH mm is zero or 1; nn is zero, 1, 2 or 3; ll is zero, 1, 2, 3 or 4; or R4 is —(CH pp is zero or 1; rr is zero, 1, 2 or 3; and oo is zero, 1, 2, 3 or 4, and the pharmaceutically acceptable salts thereof.