Patent ID: 6716596
Filing Date: 2004-04-06
Classification: C07D,C07F,C07H,C12Q

Abstract:
A composition suitable for replacement of NAD(P)+NAD(P)H system in oxido-reduction enzymatic reactions, said composition comprising a compound of general formula (I), or a salt thereof, in a combination with its 1,4-reduced form compound (II) wherein R is â€”CN, â€”C(O)NH2, â€”C(O)NHCH3, â€”C(S)NH2, â€”C(O)CH3 or â€”C(O)OCH3; wherein R1 is â€”(CH2&Parenopenst;CH2O)nYR2or wherein Y is â€”OPOOâ€”, â€”OBO2â€”, â€”OSO2â€”, CH3NHâ€”, â€”(CH2)nNHâ€”, adenine, or imidazole; wherein R2 is H, CH3, â€”(OCH2CH2)nR3, â€”(NCH2CH2)nR3 or â€”[&Parenopenst;N&boxH;P(OCH3)2]nR3; wherein X is â€”OCH3, â€”CF3, â€”O(CH2CH2O)nR3 or â€”OPOOR3; wherein R3 is H, or â€”CH3; wherein n is 1-2000.