Patent ID: 7605121
Filing Date: 2009-10-20
Classification: A61K,Y10S

Abstract:
1. A sterile Cetrorelix acetate-bulking agent lyophilisate prepared by a method comprising the steps of: (a) dissolving having the amino acid sequence of Ac-D-Nal(2)-D-pCl-Phe-D-Pal(3)-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH (b) diluting the solution with water; (c) adding bulking agent to the solution, after which the solution has a pH range between 2.5-3.0; (d) sterilizing the solution by filtration; and (e) lyophilizing the solution, producing a sterile Cetrorelix acetate lyophilisate-bulking agent thereby.