Patent ID: 6284912
Filing Date: 2001-09-04
Classification: C07C,Y02P

Abstract:
A process for preparing a compound represented by the following formula 1: ##STR12##in whichR.sub.1 represents amino-protecting group,A represents i) --OR.sub.2 wherein R.sub.2 represents hydrogen, lower alkyl, cycloalkyl or phenyl, or ii) ##STR13##wherein R.sub.3 and R.sub.4 independently of one another represent hydrogen, lower alkyl or together with the nitrogen atom to which they are attached represent a heteroalicyclic group,n represents an integer of 1 or 2, the --CN or --OR group is located at para or meta position, or its steroisomer, characterized in that a compound represented by the following formula 2: ##STR14##in whichR.sub.1, A and n are as defined above, andR represents fluorosulfonyl, trifluoromethanesulfonyl or nonafluorobutanesulphonyl, is reacted with a cyanide in the presence of a nickel catalyst.