Patent ID: 8119665
Filing Date: 2012-02-21
Classification: A61K,A61P,C07D

Abstract:
1. A packaged pharmaceutical preparation, comprising: (a) a pharmaceutical composition comprising at least one compound of the formula: or a pharmaceutically acceptable salt thereof, in combination with a physiologically acceptable carrier or excipient, in a container; and (b) instructions for using the composition to treat a patient suffering from stroke, myocardial infarction, atherosclerosis, ischemic heart disease, rheumatoid arthritis, psoriasis, cardiovascular disease, reperfusion injury, or bronchial asthma, wherein the ring system represented by is a 5 membered heteroaryl ring system, in which x is 0, A and E are independently carbon or nitrogen, and G is carbon, R i) hydrogen, hydroxy, halogen, amino, cyano, nitro, —CHO, —CONH ii) C iii) naphthyl, phenyl, phenylC R R R R R R Ar Ar each n is independently chosen from 0, 1; or 2; and y is 1.