Patent ID: 6951934
Filing Date: 2005-10-04
Classification: A61P,C07H

Abstract:
1. A method of preparing functionalized β-(1,3)-glucans comprising a reaction between a glycosyl donor and a glycosyl acceptor, wherein the glycosyl donor is selected from the group consisting of the compounds of formulae Ia and Ib: in which: X is a leaving group selected from the group consisting of: R R or together form an ethylidyl, isopropylidyl, hexafluoroisopropylidyl, cyclopentylidyl, cyclohexylidyl, cycloheptylidyl, butylidyl, 1-tert-butylethylidyl, benzylidyl, methoxybenzylidyl or 1-phenylbenzylidyl radical; R n is an integer of between 1 and 4; it being specified that in the case in which n is greater than 1, it is possible for —COR and wherein the glycosyl acceptor selected from the group consisting of the compounds of formula II: in which: Y is: R m is an integer of between 1 and 8, it being specified that in the case in which m is greater than 1, it is possible for —COR said reaction is carried out in solution in an anhydrous organic solvent, at a temperature between −80° C. and 40° C., for a period of 1 minute to 8 hours, in the presence of a promoter.