Patent ID: 9146238
Filing Date: 2015-09-29
Classification: A61K,A61P,C07K,C12Q,G01N

Abstract:
1. A method of determining if a subject will not respond to androgen therapy, the method comprising: contacting a sample from a subject with an anti-human AR-V7 antibody, wherein said anti-human AR-V7 antibody binds to epitope CKHLKMTRP (SEQ ID NO: 33), under conditions that allow for anti-human AR-V7 antibody-human AR-V7 complex formation; and detecting the level of anti-human AR-V7 antibody-human AR-V7 complex in said sample, wherein an elevation in the level of said anti-human AR-V7 antibody-human AR-V7 complex in said sample relative to the level of said anti-human AR-V7 antibody-human AR-V7 complex in a reference indicates that the subject will not respond to androgen therapy.