Patent ID: 7879853
Filing Date: 2011-02-01
Classification: A61P,C07D

Abstract:
1. A compound of formula Ia in which R1 is dibenzofuran-4-yl, R2 is hydrogen, R3 is —U—Ar2, or —V—Har2, in which U is a bond, Ar2 is 3-(R31)-phenyl, 4-(R31)-phenyl, or 2-fluoro-4-(R31)-phenyl, in which R31 is amidino, or —W—R311, in which W is methylene, ethylene, or 1,1-dimethyl-methylene, R311 is —N(R312)R313, in which R312 is hydrogen, or methyl, R313 is hydrogen, V is a bond, Har2 is 1,2,3,4-tetrahydroisoquinolin-7-yl, 1,2,3,4-tetrahydroisoquinolin-6-yl, or R33-substituted pyridyl, in which R33 is aminomethyl, or a salt thereof.