Patent ID: 6077541
Filing Date: 2000-06-20
Classification: A61K,A61P

Abstract:
A pharmaceutical capsule for oral administration of omeprazole that consists essentially of a capsule and more than one pellet wherein the pellet consists of:(a) an inert core;(b) a drug layer surrounding the inert core consisting of 20-70 wt % of omeprazole, 0.1-5 wt % of a surface active agent, 20-70 wt % of a filler, 1-20 wt % of a pharmaceutically acceptable alkaline agent and 0.1-5 wt % of a binder; and(c) a coating layer surrounding the drug layer that consists essentially of an enteric coating agent and an inert processing aid wherein the coating layer is applied directly to the omeprazole containing drug layer without a separating layer between the omeprazole containing drug layer and the coating layer.