Patent ID: 6627604
Filing Date: 2003-09-30
Classification: A61K,A61P,C07K

Abstract:
A compound of formula V wherein R1 and R2 together are double bonded O, or are each H, or H and OH, or H and Oâ€”C1-C4-alkyl: R3 and R4 together are double bonded O, or are each H, or H and OH, or H an Oâ€”C1-C4-alkyl: R5 and R7 are each H: R8 is chosen from H, OH, C1-C4-alkyl, and Oâ€”C1-C4-alkyl: R10 is H or glycosidically bonded sugar; A is a natural amino acid selected from Gly, Ala, Val, Leu, lle, Pro, Ser, Thr, Phe, Tyr, Trp, Lys, Arg, Asp, His, Glu, Asn, Gln, Cys, and Met: n is an integer chosen from 1 to 12, wherein each A in A(n) is the same or different from every other A: wherein the nitrogen atom in the isoindole ring of formula V is the N-terminal amine nitrogen of the first acid of the A(n) group; or a salt thereof.