Patent ID: 7709506
Filing Date: 2010-05-04
Classification: A61P,C07D

Abstract:
1. A method for treating pain as a condition or disease state mediated by p38 kinase activity or mediated by cytokines produced by the activity of p38 kinase comprising administering to a patient in need thereof a compound of formula (I): wherein R R or (CH R R R R R R R or R R R or R R R R X and Y are each independently selected from hydrogen, methyl and halogen; Z is halogen; m is selected from 0, 1, 2, 3 and 4, wherein each carbon atom of the resulting carbon chain may be optionally substituted with up to two groups selected independently from C n is selected from 0, 1 and 2; q is selected from 0, 1 and 2; r is selected from 0 and 1; and s is selected from 0, 1, 2 and 3; or a pharmaceutically acceptable salt thereof.