Patent ID: 7745225
Filing Date: 2010-06-29
Classification: A61P,G01N,Y10T

Abstract:
1. A method of screening for the increased potential for the development of new stretch marks in a human patient who already has stretch marks in one area of the skin comprising: establishing a total extracellular matrix protein content and a total fibroblast DNA content for normal dermal tissue from a control human subject; obtaining a sample of dermal tissue from non-stretch marked skin of said human patient; determining the total extracellular matrix protein content and the total fibroblast DNA content from said sample of dermal tissue from the human patient; comparing the extracellular matrix protein content and the fibroblast DNA content from said sample of dermal tissue from said human patient with the extracellular matrix protein content and the fibroblast DNA content for normal dermal tissue from said control subject; and determining an increased potential that the patient is predisposed for developing stretch marks when the sample of dermal tissue from said human patient has at least 36% less total extracellular matrix protein content and at least 16% less total fibroblast DNA content than the normal dermal tissue from said control subject.