Patent ID: 8580289
Filing Date: 2013-11-12
Classification: A61K,A61L,A61P

Abstract:
1. A matrix composition for supporting repair of a tissue comprising polyester polymers entangled with hyaluronic acid polymers, wherein the polyester polymers are selected from the group consisting of polylactic acid, polyglycolic acid, and a co-polymer consisting of polylactic acid and polyglycolic acid, said composition being formed by the steps of: (i) dissolving the polyester polymers in an organic solvent; (ii) blending the polyester polymers with hyaluronic acid polymers contained in an aqueous medium to form an emulsified mixture; (iii) freezing the emulsified mixture of the two polymers, and (iv) successively removing the organic solvent and water from the frozen mixture; wherein said composition is characterized by (a) retention of pore structure when hydrated and (b) the ability to support the growth of cells in vivo or ex vivo.