Patent ID: 6740648
Filing Date: 2004-05-25
Classification: A61K,A61P

Abstract:
A method for treating hypertension without affecting systemic hemodynamics comprising administering to a mammal suffering from pulmonary hypertension and in need of treatment, an effective amount of, is a compound having a formula wherein R and R5 are hydrogen or lower alkyl; R1, R2, and R3 independently are hydrogen, halo, lower alkyl, lower alkoxy, amino, alkylamino, or dialkylamino; and R4 is hydrogen, phenyl or phenyl bearing1,2, or three substituents selected from alkyl, alkoxy, thio, alkylthio, hydroxy, halo, nitro, amino, alkyl, dialkylamino, CN, CF3, alkanoyl, and aryl, and pharmaceutically acceptable salts thereof.