Patent ID: 6037448
Filing Date: 2000-03-14
Classification: A61K,A61P,C07K,C12N,Y10S

Abstract:
A synthetic peptide having an amino acid sequence of a portion of an E1, E2 or C protein of rubella virus (RV) and which contains a human T-cell determinant, wherein said amino acid sequence is at least one selected from:(a) any of the amino acid sequences 1 to 22 (SEQ ID NO: 1), 38 to 57 (SEQ ID NO: 3), 54 to 74 (SEQ ID NO: 4), 106 to 125 (SEQ ID NO: 6), 140 to 159 (SEQ ID NO: 8), 157 to 176 (SEQ ID NO: 9), 174 to 193 (SEQ ID NO: 10), 190 to 209 (SEQ ID NO: 11), 207 to 226 (SEQ ID NO: 12), 224 to 243 (SEQ ID NO: 13), 240 to 250 (SEQ ID NO: 14), 256 to 275 (SEQ ID NO: 15), 272 to 291 (SEQ ID NO: 16), 307 to 326 (SEQ ID NO: 18), 324 to 343 (SEQ ID NO: 19), 341 to 360 (SEQ ID NO: 20), 358 to 377 (SEQ ID NO: 21), 374 to 390 (SEQ ID NO: 22), 391 to 412 (SEQ NO: 23) 196 to 212 (SEQ ID NO: 24) , 198 to 233 (SEQ ID NO: 25) 219 to 233 (SEQ ID NO: 26), 198 to 240 (SEQ ID NO: 27), and 212 to 240 (SEQ ID NO: 28) of E1 protein, set forth in Table 1,(b) any of the amino acid sequences 1 to 20 (SEQ ID NO: 29), 15 to 36 (SEQ ID NO: 30), 124 to 145 (SEQ ID NO: 36), 156 to 177 (SEQ ID NO: 38), 176 to 199 (SEQ ID NO: 39), 218 to 239 (SEQ ID NO: 41) and 233 to 257 (SEQ ID NO: 42) of E2 protein, set forth in Table 2, and(c) any of the amino acid sequences 1 to 30 (SEQ ID NO: 44), 52 to 78 (SEQ ID NO: 46), 74 to 100 (SEQ ID NO: 47), 96 to 123 (SEQ ID NO: 48), 119 to 152 (SEQ ID NO: 49), 151 to 179 (SEQ ID NO: 50), 177 to 204 (SEQ ID NO: 51), 205 to 233 (SEQ ID NO: 52), 231 to 257 (SEQ ID NO: 53) and 255 to 280 (SEQ ID NO: 54) of C protein, set forth in Table 3.