Patent ID: 6413979
Filing Date: 2002-07-02
Classification: A61P,C07D

Abstract:
A compound represented by formula [I] or a pharmaceutically acceptable salt thereof: wherein Ar is a phenyl group, a thienyl group or a pyridyl group which may have one to three substituents selected from the group consisting of hydroxyl groups, amino groups, carboxyl groups, carbamoyl groups, halogen atoms, C1-C6 alkyl groups, C2-C6 alkenyl groups, C2-C6 alkynyl groups, C1-C6 alkoxy groups, C1-C6 alkoxycarbonyl groups, mono- and di-C1-C6 alkylamino groups and mono- and di-C1-C6 alkylaminocarbonyl groups, R1 is a hydrogen atom, a hydroxyl group, a cyano group, a nitro group, a carboxyl group, an amino group, a halogen atom, a C1-C6 alkyl group, a C3-C8 cycloalkyl group, a C3-C8 cycloalkyl C1-C6 alkyl group, a C2-C6 alkenyl group, a C2-C6 alkynyl group, a C1-C6 alkoxy group, a C1-C6 alkylthio group, a formyl group, a C2-C6 alkanoyl group, an aroyl group, a mono- or di-C1-C6 alkylamino group, a C3-C8 cycloalkylamino group, a C3-C8 cycloalkyl C1-C6 alkylamino group, an Nâ€”(C1-C6 alkyl)-Nâ€”(C3-C8 cycloalkyl)amino group, a C2-C6 alkanoylamino group, an aroylamino group, an Nâ€”(C1-C6 alkyl)-N-(aroyl)amino group, a C1-C6 alkylsulfonylamino group, an aryl C1-C6 alkylamino group, an N-(aryl C1-C6 alkyl)-N-(aroyl)amino group, an arylsulfonylamino group, an aryl C1-C6 alkylsulfonylamino group, a C4-C7 cyclic imino group or a C1-C6 alkoxycarbonyl group, and R2 is a hydroxyl group, an amino group, a C1-C6 alkoxy group, a mono- or di-C1-C6 alkylamino group, a C1-C6 alkylsulfonylamino group or an arylsulfonylamino or an aryl C1-C6 alkylsulfonylamino group which may have a C1-C6 alkyl group.