Patent ID: 6187370
Filing Date: 2001-02-13
Classification: A61F,A61N

Abstract:
A method for coating a medical device with a porous polymer, the method comprising:placing the medical device in a mold;placing a solution of a polymer in the mold with the medical device; wherein the solution of the polymer includes a solvent capable of phase separating from the polymer at a temperature below the freezing point of the solvent;cooling the solution of the polymer in the mold to a temperature below the freezing point of the solvent until a first fraction of particulate material is formed by solidification and phase separation of the solvent from the polymer and is dispersed within solidified polymer;cooling the solution further and at a faster rate than in the first cooling step to form a second fraction of particulate material dispersed within the solidified polymer, wherein the second fraction of particulate material has a smaller particle size than the first fraction; andremoving the particulate material from the polymer to form pores therein.