Patent ID: 7022869
Filing Date: 2006-04-04
Classification: C07B,C07C,C07D

Abstract:
1. A method of asymmetrically synthesizing an enantiomer of an acylanilide or a derivative thereof comprising: (a) contacting a compound having a ring structure, said compound having the structure of Formula IV: wherein R R R R X wherein said compound of Formula IV, when opened, provides a substituent having the structure of Formula I: wherein R R R with a compound having a structure of Formula II: wherein R R X under conditions sufficient to provide a compound having the structure of Formula III: wherein X 2 is oxygen, sulfur, sulphinyl (—SO—), sulphonyl (—SO 2 —), imino (—NH—), oxidized imino alkylimino (—NR 8 —) where R 8 is alkyl having up to 6 carbon atoms, or oxidized alkylimino; and (b) treating the compound of Formula III under conditions sufficient to provide a pure enantiomer of an acylanilide or a derivative thereof.