Patent ID: 8236344
Filing Date: 2012-08-07
Classification: A01K,A61F,A61L,C07K,G02C

Abstract:
1. A material for use in a mammalian eye, comprising: a crosslinked elastin-mimetic peptide polymer comprising pentapeptide repeats having the sequence GXGXP (SEQ ID NO:35), wherein X is any natural, modified, or unusual amino acid, wherein the material is in a shape compatible with incorporation into the eye, biocompatible, transparent to visible light, has a refractive index compatible with vision by the eye, the material is permeable to sufficient nutrients to maintain eye tissue integrity upon incorporation into an eye, and wherein the material forms a hydrogel in water and has an elastic modulus in the hydrogel state of about 0.01 MPa to about 5.0 MPa.