Patent ID: 6831177
Filing Date: 2004-12-14
Classification: A61P,C07D,Y02P

Abstract:
A compound of the formula (IV-9): wherein R6 is hydrogen; R13 is alkyl, a group of the formula: â€”R7 wherein R7 is trityl, optionally substituted sulfamoyl or alkoxymethyl, a group of the formula: C(OR8)R9â€”CHR10R11 wherein R8 is alkyl; R9, R10 and R11 each is independently hydrogen or alkyl; or R8 and R10 may be taken together to form alkylene, or hydroxymethyl; and R14 is a group of the formula: â€”R7 wherein R7 is as defined above, a group of the formula: â€”C(OR8)R9â€”CHR10R11 wherein R8, R9, R10 and R11 are defined above, or hydroxymethyl, provided that a compound wherein R6 is hydrogen; R13 is methyl; and R14 is trityl, a compound wherein R6 is hydrogen; R13 is methyl; and R14 is tetrahydropyran-2-yl, and a compound wherein R6 is hydrogen; R13 is ethyl; and R14 is trityl are excluded.