Patent ID: 7029656
Filing Date: 2006-04-18
Classification: A61K,Y10S

Abstract:
1. A nebulizer device, wherein said device contains a formulation for administration of a water-insoluble drug via the nebulizer consisting essentially of: (a) a entail volume of a solution of water-insoluble drug dissolved in a nonaqneous solvent, said small volume of solution not perturbing nebulization characteristics of a mixture of aqueous media and the small volume of solution in comparison to nebulization characteristics of the aqueous media if nebulized alone; and (b) a large volume of aqueous media, said large volume of aqueous media being large enough to operate the nebulizer; wherein, prior to administration, said small volume of solution has been mixed with said large volume of aqueous media to form a mixture that behaves as a two-phase liquid-liquid suspension in which dispersion of the solution in the aqueous media is maintained by mixing action of the nebulizer.