Patent ID: 9096492
Filing Date: 2015-08-04
Classification: A61P,C07C

Abstract:
1. A method for producing hydrated N-fullerene amino acids of general formula C 60 (H) 3 {NH(CH 2 ) n COOH} 3 .xH 2 O, wherein C 60 is fullerene; n=5, 6, or 7; and x=8 to 10, the method comprising the steps of reacting fullerene with a 15-fold molar excess of anhydrous potassium salts of amino acids of general form NH 2 (CH 2 ) n COOH, wherein n=5, 6, or 7, in an aromatic solvent medium, comprising a slow addition to a resulting suspension of a phase-transfer catalyst under stirring and heating to temperature not higher than 60 to 80° C. to form a solution that is completely decolorized and a solid residue, wherein said residue comprises potassium salts of resulting fullerene amino acid derivatives, followed by separating said residue and dissolving in water to obtain a 0.8 M aqueous solution which is then treated with a 0.1 N solution of an organic or mineral acid, then followed by centrifuging, washing, and drying the residue.