Patent ID: 8048408
Filing Date: 2011-11-01
Classification: C08F

Abstract:
1. A polymerisation process for forming polymer conjugates of biologically active compounds in which ethylenically unsaturated monomers including a zwitterionic monomer of the general formula I in which Y is an ethylenically unsaturated group selected from H A is —O— or NR A A R is hydrogen or C R R B is selected from the group consisting of a bond, or a straight and branched alkanediyl, alkylene oxaalkylene, and alkylene (oligooxalkylene) groups, optionally containing one or more fluorine substituents; and X is a zwitterionic group are polymerised by a living radical polymerisation process in the presence of an initiator, and a catalyst; in which the initiator is a compound of general formula V where: Y R where R R R wherein, in the living radical polymerization process, the group Y