Patent ID: 6218545
Filing Date: 2001-04-17
Classification: C07D,Y02P

Abstract:
A process for the preparation of a compound of the Formula I ##STR6##wherein:X is hydrogen, halogen, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.6 -haloalkyl, or nitro; andR and R' are independently hydrogen, halo, C.sub.1 -C.sub.6 -alkyl, C.sub.2 -C.sub.6 -alkenyl, C.sub.3 -C.sub.5 -alkynyl, C.sub.1 -C.sub.6 -haloalkyl, C.sub.2 -C.sub.6 -haloalkenyl, C.sub.2 -C.sub.7 -acyl, C.sub.2 -C.sub.6 -alkoxyalkyl, C.sub.2 -C.sub.6 -cyanoalkyl, C.sub.1 -C.sub.3 -alkylsulfinyl, C.sub.1 -C.sub.3 -alkylsulfonyl, or C.sub.1 -C.sub.3 -alkylthio-C.sub.1 -C.sub.3 -alkyl;the process comprising the step of treating a compound of the Formula II ##STR7##with a fluorinating agent at a temperature of from about 60.degree. to about 120.degree. C. in the presence of an organic solvent to form a compound of the Formula I; wherein:X and R are as defined above;R' is independently an alkali metal cation, hydrogen, halo, C.sub.1 -C.sub.6 -alkyl, C.sub.2 -C.sub.6 -alkenyl, C.sub.3 -C.sub.5 -alkynyl, C.sub.1 -C.sub.6 -haloalkyl, C.sub.2 -C.sub.6 -haloalkenyl, C.sub.2 -C.sub.7 -acyl, C.sub.2 -C.sub.6 -alkoxyalkyl, C.sub.2 -C.sub.6 -cyanoalkyl, C.sub.1 -C.sub.3 -alkylsulfinyl, C.sub.1 -C.sub.3 -alkylsulfonyl, or C.sub.1 -C.sub.3 -alkylthio-C.sub.1 -C.sub.3 -alkyl; andthe fluorinating agent is selected from the group consisting of: ##STR8##xenon difluoride, fluorine triethylenediamine, N-fluoro-0-benzensulfonimide, and N-fluoro-2-pyridone.