Patent ID: 9101694
Filing Date: 2015-08-11
Classification: A61L,A61P,C08L

Abstract:
1. A pliable implantable composition comprising: (i) from 5% to 20% (w/w) of a dispersing agent selected from glycerin and polyethylene glycol; (ii) from 1.0% to 6.0% (w/w) of a polymer selected from sodium carboxymethylcellulose, hydroxyethyl cellulose, hydroxypropyl methylcellulose, and methylcellulose; (iii) from 65% to 90% (w/w) of an osteoconductive component comprising anorganic bone mineral particles having diameters between 250 microns to 425 microns; and (iv) from 1% to 5% (w/w) water, wherein said pliable implantable composition has a porosity of from 5 to 30%, and wherein said pliable implantable composition is produced by: (a) preparing a quantity of a hydrogel material by mixing (i) a quantity of said polymer with (ii) a quantity of said dispersing agent, and (iii) a quantity of water; (b) mixing said hydrogel material with a quantity of said osteoconductive component to form a putty; and (c) lyophilizing said putty to form said pliable implantable composition.