Patent ID: 6075029
Filing Date: 2000-06-13
Classification: C07D

Abstract:
A compound that inhibits the activity of cellular P-450 and that has the formula: ##STR2## wherein R.sub.1 is independently a resolved enantiomer or a racemic mixture of an .omega.-1 secondary alcohol-substituted C5-C8 alkyl, optionally containing one or two nonadjacent oxygen atoms in place of a carbon atom,R.sub.2 is a C1-C20 alkyl, a C2-C20 alkenyl or C2-C20 alkynyl, which optionally contains one or two non-adjacent N or O atoms in place of a carbon atom and is substituted by furylR.sub.3 is methyl, optionally substituted by a C1-C7 alkyl, C2-C7 alkenyl, or C2-C7 alkynylR.sub.4 is hydrogen.