Patent ID: 6709654
Filing Date: 2004-03-23
Classification: A61K,A61P,C07K

Abstract:
A method of treatment that comprises blocking the B7.1/CD28 interaction in a subject having psoriasis, by administering an anti-B7.1 antibody selected from the group consisting of antibodies having the same epitopic specificity as (i) an antibody having as its variable light sequence and variable heavy sequence the amino acid sequence of SEQ ID NO:2 and SEQ ID NO:4 respectively; (ii) an antibody having as its variable light sequence and variable heavy sequence the amino acid sequence of SEQ ID NO:6 and SEQ ID NO:8 respectively; and (iii) an antibody having as its variable light sequence and variable heavy sequence the amino acid sequence of SEQ ID NO:10 and SEQ ID NO:12 respectively, whereby a subject having psoriasis is treated.