Patent ID: 8962552
Filing Date: 2015-02-24
Classification: A61K,A61P,Y10T

Abstract:
1. A water-dispersible derivative of a therapeutic active agent of low water solubility formed from at least one molecule of said active agent covalently coupled to at least one molecule of a hydrocarbon-based compound of squalene structure, said squalene structure being formed from 6 isoprene units, or an analog thereof, said analog being a substituted form of a squalenic acid, and said active agent having a solubility of less than 100 μg/ml in pure water, measured at room temperature, and being chosen from immunosuppressants, chemotherapeutic antitumor agents, antiangiogenic agents, antiviral agents, antibacterial agents, antibiotics and antiparasitic agents, substances acting on the metabolism of sugars or peptides, agents acting on the calcium channels, non-steroidal antiflogistic agents and peptide compounds.