Patent ID: 6048715
Filing Date: 2000-04-11
Classification: A61K,C07K,C08B,C08H,C12N,C12P,C12Q,C12Y,D21H,G01N,Y10S

Abstract:
A two-phase partition system for affinity separation comprising:as a first component a phase-forming oligosaccharide polymer to which a polysaccharide binding peptide binds with a Ka of 10.sup.3 M to 10.sup.7 M and as a second component a phase separation inducing agent selected from the group consisting of a polyethylene glycol polymer, a dextran, a copolymer of ethylene oxide and propylene oxide, and a salt at a concentration of at least 3 M, wherein said first and second components are each present in an amount sufficient to induce phase separation upon mixing of said first component and said second component, wherein said first component is selected from the group consisting of methyl cellulose, and ethylhydrokyethyl cellulose.