Patent ID: 7977328
Filing Date: 2011-07-12
Classification: A61K,A61P,C07D

Abstract:
1. A compound of Formula (I) or a salt thereof, wherein: R HET-1 is a 5- or 6-membered, C-linked heteroaryl ring containing a nitrogen atom in the 2-position and optionally 1 or 2 further ring heteroatoms independently selected from O, N, and S; which ring is optionally substituted on any nitrogen atom by a substituent selected from R HET-2 is a 5- or 6-membered heteroaryl ring, containing 1, 2, or 3 ring hetereoatoms independently selected from O, S, and N; which ring is substituted on an available carbon atom by a substituent selected from R R R R R R R R R R p is independently 0, 1, or 2; provided that the compound is not 3-{[5-(azetidin-1-ylcarbonyl)pyrazin-2-yl]oxy}-5-{[(1S)-1-methyl-2-(methyloxy)ethyl]oxy}-N-(5-methylpyrazin-2-yl)benzamide; 3-{[5-(azetidin-1-ylcarbonyl)pyrazin-2-yl]oxy}-5-[(1-methylethyl)oxy]-N-1H-pyrazol-3-ylbenzamide; or 3-{[5-(azetidin-1-ylcarbonyl)pyrazin-2-yl]oxy}-5-{[(1S)-2-hydroxy-1-methylethyl]oxy}-N-(5-methylpyrazin-2-yl)benzamide.