Patent ID: 9186407
Filing Date: 2015-11-17
Classification: A61K,A61P,C07D,G01N

Abstract:
1. A method for treating pain in a patient, comprising: (i) administering an amount of nicotinic acetylcholine receptor ligand to the patient, wherein the nicotinic acetylcholine receptor ligand is 5[(2R)-azetidin-2-ylmethoxy]-2-chloropyridine; and (ii) administering an amount of nicotinic acetylcholine receptor subtype α4β2 positive allosteric modulator to the patient, wherein the nicotinic acetylcholine receptor subtype α4β2 positive allosteric modulator has the formula: or is a pharmaceutically acceptable salt thereof, wherein Ar Ar wherein the amounts of (i) and (ii) together are more effective in treating pain.