Patent ID: 8974792
Filing Date: 2015-03-10
Classification: A61K,A61P,C07K,C12N,Y10S

Abstract:
1. A method of delivering a chimeric molecule to a cancer cell bearing a c-erbB2receptor, said chimeric molecule comprising an antibody that specifically binds to a c-erbB2epitope, which epitope is bound by F5 (as encoded by ATCC plasmid deposit designation PTA-7843 ) or C1 (SEQ ID NO: 2 ) and which antibody is an internalizing antibody, wherein the antibody is coupled to a liposome comprising a therapeutic composition and the chimeric molecule is comprised by a pharmaceutical composition, the method comprising administering the pharmaceutical composition in a dose effective in treating a patient suffering from a c-erbB-2 positive carcinoma.