Patent ID: 9012139
Filing Date: 2015-04-21
Classification: A61K,A61P,C12N,Y10T

Abstract:
1. A method of upregulating a function of and/or the expression of a Dystrophin family polynucleotide selected from SEQ ID NO 2 or a polyuncleotide encoding such a sequence in patient cells or tissues in vivo or in vitro comprising: contacting said cells or tissues with at least one antisense oligonucleotide of about 15-30 nucleotides in length that is complementary to and specifically hybridizable with a 15-30nucleotide region of a natural antisense polynucleotide; of the UTRN Dystrophin family polynucleotide; thereby upregulating a function of and/or the expression of the Dystrophin family polynucleotide in patient cells or tissues in vivo or in vitro.