Patent ID: 6426360
Filing Date: 2002-07-30
Classification: C07D

Abstract:
A compound of the formula: or a pharmaceutically acceptable salt thereof whereinR1 is haloalkyl, aralkylthio, aralkoxy, heteroarylthio, heteroaralkylthio, aryloxyalkyl, arylsulfonyl, arylcarbonyl, aralkylcarbonyl, aralkenyl, N-arylaminoalkyl, aminoalkyl, alkylaminoalkyl, N-arylaminoalkyl, aralkyl, N-alkyl-N-arylaminoalkyl, heteroaralkoxyalkyl, heteroaryloxyalkyl, heteroarylthioalkyl, heteroaralkyl, heteroarylalkylthioalkyl, heteroaralkoxy, heteroaryloxy, aralkylthio, arylthioalkyl, arylsulfonyl, aralkylsulfonyl, heteroarylsulfonyl, heteroarylalkylsulfonyl, arylthio, aryloxy, aralkylthioalkyl, aralkoxyalkyl, alkoxyaralkoxyalkyl, aryl or heteroaryl, wherein the aryl and heteroaryl radicals independently are substituted or unsubstituted at a substitutable position with one or more radicals selected from halo, alkylthio, alkylsulfinyl, alkyl, cyano, haloalkyl, hydroxyl, alkoxy, hydroxyalkyl and haloalkoxy; R2 and R3 are independently selected from cycloalkyl, cycloalkenyl, heterocyclo and aryl, wherein the cycloalkyl, cycloalkenyl, heterocyclo and aryl radicals independently are substituted with one or more radicals selected from hydrido, halo, alkylthio, alkylsulfinyl, alkylsulfonyl, aminosulfonyl, haloalkylsulfonyl, alkyl, cyano, carboxyl, alkoxycarbonyl, haloalkyl, hydroxyl, alkoxy, hydroxyalkyl, alkoxyalkyl, haloalkoxy, amino, alkylamino, arylamino and nitro; and R4 is hydrido, alkyl or acyl; provided that at least one of R2 and R3 is phenyl substituted with a radical selected from alkylsulfonyl and aminosulfonyl.