Patent ID: 6492185
Filing Date: 2002-12-10
Classification: C07K,G01N,Y10T

Abstract:
A method for determining the amount of apoB associated with very low density lipoprotein (VLDL) in a sample comprising the steps of:(a) mixing a sample and a VLDL-specific binding agent for a time and under conditions to form binding-agent-VLDL complexes, wherein said VLDL-specific binding agent is an antibody or fragment thereof that binds to substantially all VLDL, to low density lipoprotein (LDL) at less than about 10% of VLDL binding, to intermediate density lipoprotein (IDL) at less than about 10% of VLDL binding, and to high density lipoprotein (HDL) at less than about 10% of VLDL binding; and (b) determining the amount of apoB associated with VLDL bound to said binding-agent-VLDL complexes.