Patent ID: 8778384
Filing Date: 2014-07-15
Classification: A23K,A61K,A61P,C12N,Y02A

Abstract:
1. A composition for oral delivery, comprising one or more pharmaceutically active agents constituting in total from about 0.05% to about 10% w/w of the composition, one or more bio-adhesive polymers selected from the group consisting of chitosan, dimethyl chitosan, trimethyl chitosan, carboxymethyl chitosan and mixtures thereof and constituting in total from about 0.05% to about 10% w/w of the composition, and one or more short chain polysaccharides or oligosaccharides constituting in total from about 0.05% to about 30% w/w of the composition, wherein the composition is a crosslinked solid; wherein said one or more pharmaceutically active agents are selected from the group consisting of immunogenic peptides, immunogenic proteins, intact inactive viral particles, attenuated viral particles, infectious viral particles, intact killed prokaryotes, attenuated prokaryotes, infectious prokaryotes, intact killed protozoans, attenuated protozoans, infectious protozoans, intact killed multicellular pathogens, attenuated multicellular pathogens, infectious multicellular pathogens, recombinant subunit vaccines, recombinant vectors encoding immunogenic proteins, recombinant vectors for delivering and expressing genes encoding immunogenic proteins, and mixtures of any of these, and wherein the composition further comprises one or more adjuvant compounds.