Patent ID: 7892576
Filing Date: 2011-02-22
Classification: A61K

Abstract:
1. A prolonged release tablet comprising at least one biologically active substance and an excipient, wherein the excipient comprises: greater than or equal to 85% by wt. calcium carbonate, and at least one additive selected from the group consisting of lipid materials, polysaccharides, polyvinylpyrrolidone, polyvinylpyrrolidone derivatives, acrylic compounds, animal proteins, and mixtures thereof, and wherein said tablet provides prolonged release of the biologically active substance such that at least 10% and at most 50% of the biologically active substance is released in the first hour following oral administration of the tablet, the remaining percentage of the biologically active substance being released over a period of at least 7 hours and at most 24 hours.