Patent ID: 7879322
Filing Date: 2011-02-01
Classification: A61K,A61P,C07K,G01N

Abstract:
1. An isolated antibody that binds to a sclerostin polypeptide, comprising: (a) a heavy chain variable region CDR1 comprising an amino acid sequence consisting of SEQ ID NO: 4; (b) a heavy chain variable region CDR2 comprising an amino acid sequence consisting of SEQ ID NO: 15; (c) a heavy chain variable region CDR3 comprising an amino acid sequence consisting of SEQ ID NO: 26; (d) a light chain variable region CDR1 comprising an amino acid sequence consisting of SEQ ID NO: 37; (e) a light chain variable region CDR2 comprising an amino acid sequence consisting of SEQ ID NO: 48; and (f) a light chain variable region CDR3 comprising an amino acid sequence consisting of SEQ ID NO: 59.