Patent ID: 6808934
Filing Date: 2004-10-26
Classification: B01J,B01L,B05B,B41J,C07B,C07K,C30B,C40B,Y10T

Abstract:
A method for generating at least one fluid sample having a volume of no more than about 100 microliters on a substrate, containing a moiety of interest for crystallization and having a known composition, comprisingpositioning an acoustic ejector in acoustic coupling relationship with a reservoir of fluid, and directing acoustic radiation from the ejector into the reservoir, thereby acoustically depositing one or more reagent-containing fluid droplets at a site on the substrate surface, wherein at least one of the ejector and the reservoir is movable relative to the other, at least one of the reagent-containing fluid droplets deposited at the site contains the moiety of interest for crystallization, and at least one of the reagent-containing fluid droplets contains an agent that increases the likelihood of crystal formation.