Patent ID: 6653346
Filing Date: 2003-11-25
Classification: C07D

Abstract:
A compound represented by Formula I wherein:R1 is: hydrogen, optionally substituted (C1-C6)-alkyl, optionally substituted (C2-C10)-alkenyl, optionally substituted aryl, (optionally substituted (C1-C6)-alkoxy)carbonyl, or halogen; R2 and R3 are independently selected from optionally substituted (C1-C6)-alkyl, optionally substituted (C2-C10)-alkenyl, or optionally substituted (C3-C8)-cycloalkyl; R4 is: hydrogen, optionally substituted aryl, (optionally substituted(C1-C6)-alkyl)carbonyl, (optionally substituted aryl)carbonyl, (optionally substituted heterocyclyl)carbonyl, (optionally substituted heterocyclylalkyl)carbonyl, (optionally substituted (C1-C6)-alkoxy)carbonyl, (optionally substituted (C2-C10)-alkenyloxy)carbonyl, (optionally substituted amino)carbonyl, carboxy, formyl, or hydroxy(optionally substituted)(C1-C6)-alkyl; R5 is: hydrogen, (C1-C6)-alkyl, (C2-C10)-alkenyl, (optionally substituted alkoxy)carbonyl, carboxy, (optionally substituted amino)carbonyl, or optionally substituted aryl; provided that one of R4 or R5 is hydrogen, and that when R4 is hydrogen R5 is not hydrogen, and when R5 is hydrogen R4 is not hydrogen; R is hydrogen, (C1-C6)-alkyl, (C1-C6)-alkylcarbonyl, phosphoryl, or polyalkoxy; or R and R1 with the atoms to which they are attached form an optionally substituted ring; single stereoisomers, mixtures of stereoisomers, and the pharmaceutically acceptable salts thereof.