Patent ID: 8314241
Filing Date: 2012-11-20
Classification: C07D

Abstract:
1. A process for the preparation of crystalline anhydrous dexlansoprazole having an XRPD wherein the most intense peaks fall at 7.5, 11.4, 13.1, 13.5, 15.1, 15.4, 17.3, 20.0, 21.7, 22.5, 24.0, 26.1, 27.3 and 28.6±0.2° in 2θ, comprising dispersing dexlansoprazole in an alcoholic solvent and dissolving it by heating the dispersion of dexlansoprazole at a temperature not higher than 40° C.; cooling the solution at a temperature between 0° C. and 10° C. to form a precipitate of crystalline anhydrous dexlansoprazole; and recovering any solids.