Patent ID: 6569437
Filing Date: 2003-05-27
Classification: A61K,A61P,A61Q,Y10S

Abstract:
A method for treating at least one of an abnormal skin condition, disease, disorder and for regulating the effects of skin atrophy and for improving the texture or appearance of the skin comprising the step of:topically administering to a subject on an area of skin an effective amount of a composition comprising: (1) an acid protease which is enzymatically active below about pH 5.5; and (2) an acidic buffer which lowers the surface pH of the skin to below about pH 5.5 for a period of time effective for the treatment of at least one condition, disease, and disorder, and for regulating at least one of the effects of skin atrophy and for improving the texture and appearance of the skin, the acidic buffer being subject to neutralization by natural epidermal processes, such that the surface pH of the skin returns to about pH 5.5.