Patent ID: 8026248
Filing Date: 2011-09-27
Classification: A61P,C07D

Abstract:
1. The combination of a compound of formula (I′-1) a N-oxide, a pharmaceutically acceptable addition salt or a stereochemically isomeric form thereof, wherein A is CH, CR Q is hydrogen or —NR R R R each R R L is C L is —X L is —X aryl is phenyl or phenyl substituted with one, two, three, four or five substituents each independently selected from halo, C Het is an aliphatic or aromatic heterocyclic radical; said aliphatic heterocyclic radical is selected from pyrrolidinyl, piperidinyl, homopiperidinyl, piperazinyl, morpholinyl, tetrahydrofuranyl and tetrahydrothienyl wherein each of said aliphatic heterocyclic radical may optionally be substituted with an oxo group; and said aromatic heterocyclic radical is selected from pyrrolyl, furanyl, thienyl, pyridyl, pyrimidinyl, pyrazinyl and pyridazinyl wherein each of said aromatic heterocyclic radical may optionally be substituted with hydroxy; and R n′ is 0, 1, 2 or 3; with the proviso that Q is other than anilino, 2,4,6-trinitro-anilino, 3-methoxy-anilino, 4-methoxy-anilino, 3,4-dimethoxy-anilino, 3-chloro-4-fluoro-anilino, 4-cyano-anilino, 2-(C and another antiretroviral compound.