Patent ID: 8900635
Filing Date: 2014-12-02
Classification: A61K,A61P,B82Y

Abstract:
1. A genistein formulation comprising: nanoparticulate genistein; and one or more pharmaceutically acceptable excipients forming a suspension medium, wherein the one or more pharmaceutically acceptable excipients comprises a water soluble polymer, wherein the water soluble polymer is present in an amount ranging from about 0.5% to about 15% (w/w), the water soluble polymer comprising a polyvinylpyrrolidone (PVP), wherein the nanoparticulate genistein exhibits a D (0.50) of 0.5 μm or less and the one or more pharmaceutically acceptable excipients are selected such that the nanoparticulate genistein is suspended within the suspension medium, and wherein the nanoparticulate genistein is present in the genistein formulation at a concentration selected from a concentration of between 250 mg/mL and 500 mg/mL, a concentration of between 250 mg/mL and 400 mg/mL, a concentration of between 250 mg/mL and 350 mg/mL, and a concentration of between 275 mg/mL and 325 mg/mL.