Patent ID: 6146827
Filing Date: 2000-11-14
Classification: A01K,A61K,A61P,C07K,Y02A

Abstract:
A method for detecting a RATH nucleic acid molecule in a T helper cell sample comprising contacting a T helper cell sample with a reagent which detects the RATH nucleic acid molecule in the sample, wherein the RATH nucleic acid molecule comprises:(a) a nucleotide sequence that encodes the amino acid sequence of SEQ ID NO:2, SEQ ID NO:4, or the amino acid sequence encoded by the cDNA clone of ATCC Accession No. 98116;(b) a nucleotide sequence that encodes an RGS domain of the amino acid sequence of SEQ ID NO:2, SEQ ID NO:4, or the amino acid sequence encoded by the cDNA clone of ATCC Accession No. 98116; or(c) a nucleotide sequence that hybridizes to the complement of a nucleotide sequence that encodes the amino acid sequence of SEQ ID NO:2, SEQ ID NO:4, or the amino acid sequence encoded by the cDNA clone of ATCC Accession No. 98116 under conditions comprising incubation at 65.degree. C. in 0.5 M NaHPO.sub.4, 7% SDS, 1 mM EDTA followed by washing in 0.1.times.SSC/0.1% SDS at 68.degree. C.