Patent ID: 6252043
Filing Date: 2001-06-26
Classification: A61K,A61P,C07K,C12N,Y02A

Abstract:
An isolated VCAM1 polypeptide selected from the group consisting of the following polypeptides:(a) a polypeptide that consists of an amino acid sequence shown in FIG. 3 extending from amino acid number 24 (phenylalanine) to, and including, amino acid number 107 (isoleucine);(b) a polypeptide that consists of an amino acid sequence shown in FIG. 3 extending from amino acid number 108 (Glutamine) to, and including, amino acid number 216 (Leucine);(c) a polypeptide that consists of an amino acid sequence shown in FIG. 3 extending from amino acid number 217 (Glutamine) to, and including, amino acid number 309 (Alanine);(d) a polypeptide that consists of an amino acid sequence shown in FIG. 3 extending from amino acid number 310 (Phenylalanine) to, and including, amino acid number 412 (Leucine);(e) a polypeptide that consists of an amino acid sequence shown in FIG. 3 extending from amino acid number 413 (Tyrosine) to, and including, amino acid number 505 (Valine); and(f) a polypeptide that consists of an amino acid sequence shown in FIG. 3 extending from amino acid number 506 (Threonine) to, and including, amino acid number 597 (Asparagine); wherein said numbering begins at a proline residue (amino acid number 1) immediately adjacent to the N-terminal methionine shown in FIG. 3 and wherein said isolated VCAM1 polypeptide is essentially free of normally associated animal protein.