Patent ID: 6730297
Filing Date: 2004-05-04
Classification: A61K,C12N,C12Y

Abstract:
An FIV vector, comprising a 5â€² FIV LTR, a tRNA binding site, a packaging signal, a promoter operably linked to a polynucleotide encoding a protein selected from the group consisting of &bgr;-glucuronidase, neuraminidase, sphingomyelinase, sulfatase, arylsulfatase &bgr;, &agr;-neuraminidase, gangliosidase, tripeptidyl protease, CLN3, and palmitoyl protein thioesterase (PPT), an origin of second strand DNA synthesis and a 3â€² FIV LTR, wherein the FIV vector is devoid of vif and ORF 2.