Patent ID: 6699886
Filing Date: 2004-03-02
Classification: A61K

Abstract:
A method for treating an inflammatory disease or reducing an inflammatory reaction, said method comprising:administering a SOC inhibitor, thereby treating said inflammatory disease or reducing said inflammatory reaction, wherein said SOC inhibitor is a compound selected from the group consisting of: wherein:R1 is a (C4-C18)alkylene having at least 2 sites of unsaturation and substituted with 1 R3, wherein R3 a member selected from the group consisting of: wherein n is about 1 to about 10, and â€”CH3; andR2 is a member selected from the group consisting of optionally substituted (C1-C6)alkyl, optionally substituted (C1-C6)alkoxy, acyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted heteroarylalkyl, and optionally substituted heteroarylalkoxy, wherein each substituent is independently selected from the group consisting of hydroxyl, bromo, fluoro, chloro, iodo, mercapto or thio, cyano, cyanoamido, alkylthio, aryl, carboxyl, carbalkoyl, alkyl, alkenyl, nitro, amino, alkoxyl and amido.