Patent ID: 6566053
Filing Date: 2003-05-20
Classification: C12Q

Abstract:
A method of providing a prognosis for at least one of colorectal, stomach, and pancreatic tumor cells comprising:obtaining sample containing DNA from a potential colorectal, stomach, or pancreatic tumor; and analyzing DNA of said sample to determine whether mutations in genomic DNA have occurred, wherein the mutations are at least one of deletions and insertions of one or a few nucleotides in reiterated sequences or microsatellite sequences, wherein the reiterated sequences are characterized as having multiple adjacent occurrences of the same nucleotide, dinucleotide pair or nucleotide triplet, and wherein the microsatellite sequences are characterized as having 1-6 base pair tandem repeats, wherein said tumors having said mutations have a prognosis of at least one of the following: being less invasive than tumors without said mutations; having a lower rate of recurrence than tumors without said mutations; and being less likely to have metastasis than tumors without said mutations.