Patent ID: 8623380
Filing Date: 2014-01-07
Classification: A61K,C12N,Y02A

Abstract:
1. A method of boosting immunity against diphtheria, tetanus, and pertussis in an adolescent or adult subject previously vaccinated with a DTPa vaccine, wherein the diphtheria, the tetanus, and the pertussis components of said DTPa vaccine are diphtheria (D) toxoid, tetanus (T) toxoid, pertussis toxoid (PT), FHA (filamentous hemagglutinin) and pertactin (69K) antigens, said method consisting of vaccinating the subject with a booster vaccine composition comprising a dose of: (a) a combination of antigens consisting of 2.5 Lf of the diphtheria (D) toxoid, 5 Lf of the tetanus (T) toxoid, 8 μg of the PT (pertussis toxoid), 8 μg FHA (filamentous hemagglutinin), and 2.5 μg of the pertactin (69K) and (b) an adjuvant; and wherein said previous vaccination was with a higher dose of each of said antigens present in said DTPa vaccine.