Patent ID: 6716442
Filing Date: 2004-04-06
Classification: A01N,A61P

Abstract:
A method for the eradication of fleas in domestic or accommodation premises of a domestic or laboratory mammal, comprising topically applying, at least monthly, to a localized region having a surface area of 10 cm2 or less on the domestic or laboratory mammal, a parasitically effective amount of a spot-on topical preparation comprising a veterinarily acceptable vehicle and a compound of Formula I: in which:R1 is CN; R2 is S(O)nR3; R3 is haloalkyl; R4 is NH2; R11 and R12 are, independently of one another a halogen atom; R13 is a haloalkyl; n is an integer equal to 0, 1 or 2; X is a Câ€”R12 radical; wherein, when the preparation is so applied to the mammal, through the action of the compound and the vehicle, the compound diffuses over the mammal's body, and then dries without crystallization and without modifying the mammal's appearance and coat, and wherein said mammal is selected from the group consisting of canine and feline.