Patent ID: 7108992
Filing Date: 2006-09-19
Classification: A61K,C07K,C12Q,G01N

Abstract:
1. An antibody specific for Ataxia-Telangiectasia Mutated kinase wherein the antibody specifically recognizes the phosphorylation state of a serine corresponding to residue 1981 of Ataxia-Telangiectasia Mutated kinase of SEQ ID NO: 1 in a peptide sequence comprising Ser-Leu-Ala-Phe-Glu-Glu-Gly-Ser-Gln-Ser-Thr-Thr-Ile-Ser-Ser (SEQ ID NO: 5) or Ser-Leu-Ala-Phe-Glu-Glu-Gly-Ser(P)-Gln-Ser-Thr-Thr-Ile-Ser-Ser (SEQ ID NO: 6), in which Ser(P) indicates phosphorylation of serine.