Patent ID: 8795711
Filing Date: 2014-08-05
Classification: A61F,A61K,A61L,A61P

Abstract:
1. A method of treating glaucoma of a patient with a punctal plug, the method comprising: placing the punctal plug in a lacrimal canaliculus of an eye, wherein the punctal plug comprises; a silicone plug body comprising a drug insert; the drug insert comprising: a drug core comprising a therapeutic agent contained in a matrix; and an impermeable sheath body partially covering the drug core, wherein the sheath body is configured to provide an exposed proximal end of the drug core in direct contact with tear fluid that releases therapeutic agent to the eye when the drug insert is disposed within a channel of the punctal plug and the punctal plug is inserted into the lacrimal canaliculus of the patient; wherein the distal end of the drug insert is sealed with an adhesive, and wherein the method comprises delivering at least 10 ng per day of the therapeutic agent from the punctal plug to the eye of the patient for at least 21 days.