Patent ID: 9145583
Filing Date: 2015-09-29
Classification: B01J,B82Y,C12Q

Abstract:
1. A multi-spot metal-capped nanostructure array nucleic acid chip, comprising: (a) a substrate; (b) a first metal thin film layer formed on the substrate; (c) a nanostructure layer, including multi-spots formed on the first metal thin film layer, wherein nanostructures are arrayed on respective spot surfaces of the multi-spots at regular intervals; (d) a second metal thin film layer formed on the surface of the nanostructure layer; and (e) probe nucleic acids immobilized on the second metal thin film layer, wherein the probe nucleic acids are capable of detecting a plurality of target nucleic acids and the target nucleic acids in the plurality of target nucleic acids are each less than 190 nucleotides in length, wherein: