Patent ID: 8445686
Filing Date: 2013-05-21
Classification: A61P,C07D

Abstract:
1. A compound of the formula I or a physiologically tolerated acid addition salt thereof, wherein: R R R R R X is a single bond, linear or branched C W is a cyclic radical selected from phenyl, naphthyl, pyridyl, benzo-1,4-dioxanyl, and pyrrolidinyl; and where the cyclic radical W may carry 1, 2, 3, 4 or 5 substituents R R Z is halogen, OR Y is linear or branched C each R where aryl in R where heterocyclyl is a saturated, partly unsaturated or aromatic 5 or 6-membered heterocyclic ring containing 1, 2, 3 or 4 heteroatoms selected from O, S and N and optionally 1 or 2 carbonyl groups as ring members, where the aliphatic and cycloaliphatic moieties in the radicals R where the aromatic and heterocyclic moieties in the radicals R R R or R R each R where aryl is selected from phenyl and naphthyl, where heterocyclyl is a saturated, partly unsaturated or aromatic 5 or 6-membered heterocyclic ring containing 1, 2, 3 or 4 heteroatoms selected from O, S and N and optionally 1 or 2 carbonyl groups as ring members, where the aromatic and heterocyclic moieties in the radicals R m is 0, 1 or 2; provided, however, that the compound of the formula I does not include N[1-(3-chlorophenyl)-2-hydroxyethyl]-4-(2-fluoro-5-methyl-pyridin-4-yl)-benzamide.