Patent ID: 8242139
Filing Date: 2012-08-14
Classification: A61P,C07D

Abstract:
1. A compound of formula (I), or a pharmaceutically acceptable salt, prodrug, salt of a prodrug, or a combination thereof, wherein: G G T, at each occurrence, is independently selected from the group consisting of alkyl, alkenyl, alkynyl, halogen, —CN, —NO two of the adjacent substituents T, together with the carbon atoms to which they are attached, form a monocyclic ring selected from the group consisting of phenyl, heterocycle and heteroaryl, wherein each ring is optionally further substituted with 1, 2 or 3 substituents selected from the group consisting of oxo, alkyl, alkenyl, alkynyl, halogen, —CN, —NO G W W W W R R R R wherein 1, 2, 3, or 4 hydrogen atoms attached to the ring carbon of the cycloalkyl and the monocyclic heterocycle are optionally replaced with radicals selected from the group consisting of alkyl, halogen, —CN, haloalkyl, —C(O)O(R W W R R R R L L R R Q is alkyl, alkenyl, alkynyl, haloalkyl, G wherein Z is alkyl, alkenyl, alkynyl, haloalkyl, G Y Y Y Y wherein the cycloalkenyl, cycloalkyl, heterocycle, heteroaryl, aryl, the aryl moiety of the arylalkyl, the heteroaryl moiety of the heteroarylalkyl, the cycloalkyl moiety of the cycloalkylalkyl, the heterocycle moiety of the heterocyclealkylalkyl, and the cycloalkenyl moiety of the cycloalkenylalkyl as represented by X, G R R R r, s, t, u, and v, at each occurrence, is independently 1, 2, 3, 4, 5 or 6.