Patent ID: 8304245
Filing Date: 2012-11-06
Classification: B01L,G01N

Abstract:
1. A method for performing a population analysis on a plurality of cells while in transit in at least one dynamic microfluidic pathway, the method comprising: providing a population of cells having cell surface indicia; transmitting the population of cells through the microfluidic pathway; analyzing the cell surface indicia to obtain a first set of data corresponding to each cell of the population of cells; utilizing a processor to compare the first set of data with at least one preset user criteria to identify at least one cell satisfying the preset user criteria; utilizing the processor to control operation of a cell lyser to selectively lyse the at least one cell while it transits a microfluidic pathway to produce cell debris that exposes cell interior indicia, wherein cells that do not satisfy the preset user criteria are not lysed; and analyzing the cell interior indicia for at least one of a molecule and a cellular component.