Patent ID: 6759557
Filing Date: 2004-07-06
Classification: A61K,A61P,A61Q,C07C

Abstract:
A melanin-synthesis inhibitor composition containing at least one macrocyclic compound represented by Formula (1) wherein X signifies a member selected among the group consisting of â€”Câ€”, â€”CHOHâ€” and â€”COâ€”CHOHâ€”; R signifies a chain hydrocarbon having 13 to 24 carbon atoms and forming a ring with X; and R either is saturated or contains 1 to 3 unsaturated bonds, and may be substituted with a lower alkyl group of 1 to 3 carbon atoms, with the proviso that, when X is â€”COâ€”CHOHâ€”, the number of carbon atoms in said chain hydrocarbon is not 13; and, optionally, a skin whitening agent and/or ultra-violet ray absorbent.