Patent ID: 6060042
Filing Date: 2000-05-09
Classification: A61K,A61P,A61Q

Abstract:
A cholesteric liquid-crystalline composition comprisinga) at least one chiral, liquid-crystalline, polymerizable monomer of the formula I,[Z.sup.1 -Y.sup.1 -(A.sup.1).sub.m -Y.sup.2- M.sup.1 -Y.sup.3 -].sub.n -XIby means of which a cholesteric liquid-crystalline phase having a pitch of less than 450 nm can be obtained, where the variables, independently of one another, have the following meanings:A.sup.1 is a spacer having a chain length of from 1 to 30 carbon atoms,Y.sup.1 to Y.sup.3 are a chemical bond, --O--, --S--, --C(.dbd.O)--O--, --O--C(.dbd.O)--, --CH.dbd.CH--C(.dbd.O)--O--, --O--C(.dbd.O)--O--, --C(.dbd.O)--N(R)-- or --(R)N--C(.dbd.O)--, --CH.sub.2 --O--, --O--CH.sub.2 --, --CH.dbd.N--, --N.dbd.CH-- or --N.dbd.N--,M.sup.1 is a mesogenic group,R is hydrogen or C.sub.1 -C.sub.4 -alkyl,Z.sup.1 is hydrogen, C.sub.1 -C.sub.4 -alkyl, a polymerizable group or a radical carrying a polymerizable group,X is an n-valent chiral radical,m is 0 or 1,n is from 1 to 6,where the radicals Z.sup.1, Y.sup.1, Y.sup.2, Y.sup.3, A.sup.1 and M.sup.1 may be identical or different and at least one radical Z.sup.1 is a polymerizable group or a radical containing a polymerizable group if n is greater than 1, orb) a mixture ofb.sub.1) at least one achiral, liquid-crystalline, polymerizable monomer of the formula IIZ.sup.2 -Y.sup.4 -(A.sup.2).sub.o -Y.sup.5 -M.sup.2 -Y.sup.6 -(A.sup.3).sub.p -Y.sup.7 -Z.sup.3 IIwhere the variables, independently of one another, have the following meanings:A.sup.2 and A.sup.3 are a spacer having a chain length of from 1 to 30 carbon atoms,M.sup.2 is a mesogenic group,Y.sup.4 to Y.sup.7 are a chemical bond, --O--, --S--, --C(.dbd.O)--O--, --O--C(.dbd.O)--, --CH.dbd.CH--C(.dbd.O)--O--, --O--C(.dbd.O)--O--, --C(.dbd.O)--N(R.sup.1)-- or --(R.sup.1)N--C(.dbd.O)--, --CH.sub.2 --O--, --O--CH.sub.2 --, --CH.dbd.N--, --N.dbd.CH-- or --N.dbd.N--,R.sup.1 is hydrogen or C.sub.1 -C.sub.4 -alkyl,o and p are 0 or 1Z.sup.2 and Z.sup.3 are hydrogen, C.sub.1 -C.sub.4 -alkyl, a polymerizable group or a radical carrying a polymerizable group,where at least one of the variables Z.sup.2 and Z.sup.3 is a polymerizable group or a radical carrying a polymerizable group, andb.sub.2) at least one chiral additive by means of which a cholesteric liquid-crystalline phase having a pitch of less than 450 nm can be obtained,as UV filters in cosmetic and pharmaceutical preparations for protecting the human skin or human hair against sunlight, alone or together with compounds which absorb in the UV region and are known for cosmetic and pharmaceutical preparations.