Patent ID: 9102602
Filing Date: 2015-08-11
Classification: C07C

Abstract:
1. A method for producing an isothiocyanate compound comprising a carboxyl group, the isothiocyanate compound represented by formula (2): wherein m, n, A and B are, respectively, as defined for formula (1), the method comprising reacting (i) an amino compound comprising a carboxyl group, the amino compound represented by formula (1): wherein m and n, each are an integer of 1, A is a phenylene group that is unsubstituted or substituted with one or more halogen atoms or one or more nitro groups, and B is a single bond, with (ii) thiocarbonyldiimidazole in a solvent in the presence of a base; followed by treating with acid and at least one poor solvent selected from the group consisting of water, a C then filtering said isothiocyanate compound.