Patent ID: 8242124
Filing Date: 2012-08-14
Classification: A61P,C07D

Abstract:
1. A compound of Formula I, including pharmaceutically acceptable salts thereof: wherein A is: wherein B is selected from the group consisting of: and further wherein a is selected from the group consisting of H, halogen and methoxy; b and c are selected from the group consisting of H and halogen; d is selected from the group consisting of H, halogen, methoxy and Group C; e is H; f and g are selected from the group consisting of H, (C h and i are selected from the group consisting of H, (C j and k are selected from the group consisting of H, F, (C l, m and n are selected from the group consisting of H, OH, CN, (C Ar is selected from the group consisting of phenyl and pyridinyl; wherein said phenyl and pyridinyl are independently optionally substituted with one to three same or different halogens or from one to three same or different substituents selected from Group E; Group C is selected from the group consisting of COOR, CONR Group D is selected from the group consisting of pyrazinyl and triazolyl; wherein said pyrazinyl and triazolyl are independently optionally substituted with one to three same or different halogens or from one to three same or different substituents selected from Group E; Group E is selected from the group consisting of OH, OR, CN, COOR, CONR R, R