Patent ID: 6531149
Filing Date: 2003-03-11
Classification: A61K,A61P,A61Q

Abstract:
Active substance-containing patch for controlled release of hormonal active substance consisting of at least one of estradiol or its pharmaceutically acceptable derivatives, or at least one of estradiol or its pharmaceutically acceptable derivatives and at least one gestagen in a molar ratio of the former to the latter of 1:1 to 1:10, to human or animal skin, comprising a backing layer, an active substance-containing reservoir connected thereto which is suitable for active substance release and which comprises a layer of at least one pressure-sensitive adhesive containing polymer consisting essentially of acrylic polymer, and a detachable protective layer, wherein the acrylic polymer pressure-sensitive adhesive contains said active substance in a concentration of 1-20%-wt. based on the total weight of the reservoir, wool wax or components thereof in a concentration of 1-30%-wt. based on the total weight of the reservoir and zinc oxide in a concentration of 1-30%-wt. based on the total weight of the reservoir.