Patent ID: 7547770
Filing Date: 2009-06-16
Classification: A23J,C07K

Abstract:
1. A method for separating the proline-rich polypeptides essentially free of peptides and proteins of about 10,000 Daltons or greater from the globular proteins having a molecular weight of between 10,000 and 500,000 Daltons in bovine colostrum, the method comprising the steps of: (a) subjecting at least a portion of a bovine colostrum sample to at least one separation procedure comprising an ion exchange separation to yield separated proline-rich polypeptides essentially free of peptides and proteins of about 10,000 Daltons or greater and separated globular proteins having a molecular weight of between 10,000 and 500,000 Daltons, wherein no more than about 10% of the separated proline-rich polypeptides are denatured; and (b) collecting the separated proline-rich polypeptides; wherein at least 90% of the separated proline-rich polypeptides have a molecular weight of no more than about 2,500 Daltons.