Patent ID: 6083383
Filing Date: 2000-07-04
Classification: A61B,A61L,B01D,Y10T

Abstract:
An apparatus for producing clinically ready fibrinogen of high concentration and high tensile strength from autologous plasma of a patient as part of a sterile and closed system, comprising:receiving means for receiving a blood concentration from the patient;a reservoir for providing a desirable amount of an anticoagulant to the blood concentration;a plasma membrane separator to extract and separate the autologous plasma from other undesirable compositions in the blood concentration of the patient;means for adding a desirable amount of ether or other suitable solvents containing an --OH group;a second membrane separator to provide separation of fibrinogen from other compositions in the autologous plasma in the presence of said desirable amount of ether or other suitable solvents containing an --OH group wherein said second membrane separator further comprises a mixing means to provide thorough mixing of the autologous plasma with the ether or the suitable solvents containing an --OH group;a fibrinogen collector connected to the second membrane separator to receive the fibrinogen separated and transferred from the second membrane separator;a vacuum pump connected to the fibrinogen collector through a sterile filter to remove the ether or the other suitable solvents containing an --OH group contained within the fibrinogen collector;a freezer enclosing said second membrane separator and said fibrinogen collector to provide adjustable temperatures to the autologous plasma in the second membrane separator and to the fibrinogen in the fibrinogen collector; andcommunication means for providing blood transferring among the receiving means, the reservoir, the plasma membrane separator, the second membrane separator and the fibrinogen collector wherein said communication means comprises at least one peristaltic pump to maintain blood transport in the sterile and closed system;wherein by the use of said apparatus as part of a closed and sterile system, the concern of blood contamination due to exposure with air can be eliminated.