Patent ID: 6180373
Filing Date: 2001-01-30
Classification: C12N,C12P,C12R,Y10S

Abstract:
A tryptophan producing strain of microorganism,said tryptophan producing strain of microorganism being selected from the group consisting of E. coli and Corynebacteria and is tryptophan feedback resistant and serine feedback resistant and wherein said serine feedback resistance is by a mutation in a serA allele, where the mutated serA allele codes for a protein which has a K.sub.i value for serine between 0.1 mM and 50 mM; andwherein said tryptophan feedback resistance is by a trpE allele which codes for a protein which has a K.sub.i value for tryptophan between 0.1 mM and 20 mM.