Patent ID: 7488495
Filing Date: 2009-02-10
Classification: A61K,A61P

Abstract:
1. A method of treating hyperkalemia in an animal subject, the method comprising administering to said animal subject an effective amount of a potassium-binding, cation-exchange polymer, the cation-exchange polymer comprising at least one polymer selected from a crosslinked carboxylic polymer, a crosslinked sulfonic polymer, a crosslinked sulfamic polymer, a crosslinked phosphonic polymer, and an anhydride thereof, the crosslinked polymer comprising an electron-withdrawing substituent attached to a carbon atom alpha or beta to an acid group of said polymer and being orally administered in a form having a combination of counterions selected from Ca whereby the potassium-binding, cation-exchange polymer binds and removes potassium from a gastrointestinal tract of said animal subject.