Patent ID: 6818644
Filing Date: 2004-11-16
Classification: A61P,C07C,C07D

Abstract:
A compound of the formula (I) whereinn denotes the number 1, 2, 3, 4 or 5, m denotes the number 2, X denotes a carbon-carbon bond, Ra denotes a phenyl group or a heteroaryl group chosen from pyridinyl, pyrimidinyl, thiophenyl, oxazolyl and 1, 2, 4 thiadiazolyl each substituted by the groups R1 and R2, wherein R1 denotes a hydrogen, fluorine, chlorine, a C1-3-alkyl group wherein the hydrogen atoms of the alkyl are optionally wholly or partly replaced by fluorine atoms, a C1-4-alkoxy group, a phenoxy, phenyl-C1-3-alkoxy, nitro or amino, wherein the abovementioned phenyl of the phenoxy is optionally substituted by chlorine or methoxy, and R2 denotes a hydrogen, chlorine or C1-4-alkoxy, or Ra denotes a heteroaryl chosen from pyridinyl, pyrimidinyl thiophenyl, oxazolyl and 1, 2, 4 thiadiazolyl or phenyl group which is substituted in each case by a phenyl group, Rb and Rc independently of one another denote a hydrogen atom or a C1-3-alkyl group and Rf denotes C1-6-alkyl wherein the hydrogen atoms of the alkyl are optionally wholly or partly replaced by fluorine atoms, phenyl-C1-3-alkyl wherein the phenyl is optionally substituted by fluorine or C1-3-alkoxy, Rg is hydrogen; or the enantiomeres, diastereomers or the salts thereof.