Patent ID: 8568286
Filing Date: 2013-10-29
Classification: A61M,A61N

Abstract:
1. A method to enhance the efficacy of engraftment of cells, comprising: administering to a mammal in need of therapy a composition comprising donor cells for engraftment to an injured region which cells are associated with a complex which comprises a force responsive moiety that is responsive to a magnetic field; and applying a magnetic field to the mammal from an implantable magnetic field generating device in the mammal, which device is on the epicardium near the injured region, in an amount and for a time effective to increase the engraftment of the cells at the injured region, wherein the implantable magnetic field generating device is coupled to an implantable medical device including a field controller adapted to control the generation of the magnetic field which includes a field generation timer adapted to time one or more predetermined durations during which the magnetic field is generated with a predetermined duty cycle.