Patent ID: 6165500
Filing Date: 2000-12-26
Classification: A61K,A61P,Y10T

Abstract:
A method of transporting medical agents through the skin of a mammal, comprising(A) preparing transfersomes comprising a pharmaceutically acceptable lipid and a pharmaceutically acceptable surfactant which is compatible with said lipid, said transfersomes being contained in a pharmaceutically acceptable medium for application onto said skin, said transfersomes containing said lipid and said surfactant in a ratio which enables said transfersomes to undergo sufficient deformation to enable said transfersomes to pass through the skin of said mammal as an entity, such that the total concentration of said lipid in said medium is from about 0.1% to about 30% by weight, and the ratio of lipid to surfactant is from about 5.5:1 to about 1:500, and(B) applying a suitable amount of said transfersomes in said medium onto the skin of said mammal such that an effective dose of said lipid, said surfactant, or a further medical agent associated with said transfersomes is absorbed into said mammal.