Patent ID: 7662958
Filing Date: 2010-02-16
Classification: A61P,C07D

Abstract:
1. A process for preparation of a compound, a stereoisomer of the compound, a tautomer of the compound, or a pharmaceutically acceptable salt of the compound, stereoisomer, or tautomer, wherein: the compound corresponds to formula (I): A is thienyl; R as to R R as to R each R as to R each R as to R with a reagent selected from the group consisting of (1) carbon disulfide and a methylating agent, (2) tris(methylthio)methyl methyl sulfate, and (3) tris(methylthio)methyl methyl tetrafluoroborate, in the presence of a base, to provide a compound of formula (27) (b) contacting the compound of formula (27) with a compound of formula (13)