Patent ID: 6174867
Filing Date: 2001-01-16
Classification: A61P,C07H

Abstract:
A compound of formula I: ##STR7##whereinA is selected from the group consisting of arylene, cycloalkylene, cycloalkenylene, heteroarylene and divalent heterocyclic;B is selected from the group consisting of cycloalkyl, cycloalkenyl and heterocyclic;Y is selected from the group consisting of alkylene, substituted alkylene and --N(R.sup.1)--, wherein R.sup.1 is selected from the group consisting of --C(O)R.sup.2 and --SO.sub.2 R.sup.3, wherein R.sup.2 and R.sup.3 are independently selected from the group consisting of alkyl, alkenyl, alkaryl, alkoxyalkyl, aryl, cycloalkyl, cycloalkenyl, heteroaryl, heterocyclic and thioalkoxyalkyl;Y' is selected from the group consisting of oxygen, sulfur, --S(O)--, --SO.sub.2 --, alkylene, substituted alkylene, and --N(R.sup.4)--, wherein R.sup.4 is selected from the group consisting of hydrogen, alkyl, alkenyl, alkaryl, alkoxyalkyl, aryl, cycloalkyl, cycloalkenyl, heteroaryl, heterocyclic, thioalkoxyalkyl, --C(O)R.sup.5 and --SO.sub.2 R.sup.6, wherein R.sup.5 and R.sup.6 are independently selected from the group consisting of alkyl, alkenyl, alkaryl, alkoxyalkyl, aryl, cycloalkyl, cycloalkenyl, heteroaryl, heterocyclic and thioalkoxyalkyl; andR.sup.a, R.sup.b, R.sup.c and R.sup.d are each independently selected from the group consisting of hydrogen; sulfate; --C(O)R.sup.7, wherein R.sup.7 is selected from the group consisting of alkyl, alkenyl, alkaryl, alkoxyalkyl, aryl, cycloalkyl, cycloalkenyl, heteroaryl, heterocyclic and thioalkoxyalkyl; and --P(O)(OR.sup.8).sub.2, wherein each R.sup.8 is independently selected from the group consisting of hydrogen, alkyl, alkenyl, alkaryl, alkoxyalkyl, aryl, cycloalkyl, cycloalkenyl, heteroaryl, heterocyclic and thioalkoxyalkyl;and pharmaceutically acceptable salts thereof.