Patent ID: 9175049
Filing Date: 2015-11-03
Classification: A61K,A61P,C07K

Abstract:
1. A composition comprising isolated and purified immunogenic proteins of Mycobacterium avium subspecies paratuberculosis and a pharmaceutically acceptable carrier, wherein said immunogenic proteins are provided in an amount effective to stimulate an immune response in an animal against said Mycobacterium avium subspecies paratuberculosis , and said immunogenic proteins comprise MAP1087 and at least two of MAP1204, MAP1272c, and MAP2077c wherein said MAP1087 comprises SEQ ID NO: 1; wherein said MAP1204 comprises SEQ ID NO: 2; wherein said MAP1272c comprises SEQ ID NO: 3; and wherein said MAP2077c comprises SEQ ID NO: 4, wherein said pharmaceutically acceptable carrier is selected from the group consisting of physiological saline, phosphate buffered saline, mineral oil, vegetable oil, aqueous carboxymethyl cellulose, and polyvinylpyrrolidone.