Patent ID: 7132395
Filing Date: 2006-11-07
Classification: A61K,A61P,C07K

Abstract:
1. A method of inhibiting infection of a host cell by human rhinovirus (HRV) in tissues susceptible to such infection, said method comprising contacting said HRV with a polypeptide comprising a fragment of human rhinovirus major receptor (HRR) [SEQ ID NO:1], said fragment comprising the HRV binding site and being selected from the group consisting of the following sets of HRR domains: I and II (tICAM(1-185)), I, II, and IlI (tICAM(1-284)), I, II, III, and IV (tICAM(1-385)), or I, II, III, IV, and V (tICAM(1453)) said contact being under conditions which permit said HRV to bind to said polypeptide, whereby said HRV is inhibited from infecting said host cell.