Patent ID: 7718627
Filing Date: 2010-05-18
Classification: A61P,C07K,C12N

Abstract:
1. A composition comprising a vector wherein the vector comprises a nucleotide sequence coding for a protein that consists essentially of an antibody that binds 5T4wherein said antibody comprises 5T4 complementarity determining regions (CDRs) wherein the CDRs are the amino acid sequences KASQSVSNDVA (SEQ ID NO: 26), YTSSRYA (SEQ ID NO: 27), QQDYNSPPT (SEQ ID NO: 28), GYYMH (SEQ ID NO: 29), R1NPNNGVTLYNQKFKD (SEQ ID NO: 30) and STMITNYVMDY (SEQ ID NO: 31), wherein the vector is capable of expressing the antibody in a mammalian cell, and wherein the composition further comprises a pharmaceutically acceptable carrier, diluent, excipient or adjuvant.