Patent ID: 7351770
Filing Date: 2008-04-01
Classification: C12Q

Abstract:
1. An ionic hydrophilic high molecular weight redox polymer for use in enzymatic electrochemical-based sensors employing a charged redox enzyme, the ionic hydrophilic high molecular weight redox polymer comprising: a hydrophilic polymer backbone that includes ionic portions; and a plurality of attached redox mediators covalently attached to the hydrophilic polymer backbone in a flexible pendant manner such that the redox mediators can segmentally diffuse between the charged redox enzyme and an electrode of the enzymatic electrochemical-based sensor, wherein the molecular weight of the ionic hydrophilic high molecular weight polymer is greater than 16 Kg/mol as a weight average molecular weight, and wherein an ionic charge of the ionic portions is predetermined to result in an affinity between the ionic portions and the charged redox enzyme of an enzymatic electrochemical-based sensor and that minimizes leaching of the redox enzyme and fosters activity between the redox enzyme and redox mediator.