Patent ID: 6616989
Filing Date: 2003-09-09
Classification: C07D,C09K

Abstract:
An isoxazole derivative of the formula (I) where the symbols and indices have the following meanings:T is R1 and R2 are identical or different and are each hydrogen, F, CN or a straight-chain or branched C1-C20-alkyl or C2-C20-alkenyl radical (with or without asymmetric carbon atoms), where a) one to three nonterminal CH2 groups may be replaced, independently of one another, by â€”Oâ€”, or â€”C(&boxH;O)â€”, with the proviso that heteroatoms cannot be linked directly to one another; and/or b) one CH2 group may be replaced by â€”CH&boxH;CHâ€” or â€”Câ‰¡Câ€”; and/or c) one CH2 group may be replaced by â€”Si(CH3)2â€”, cyclopropane-1,2-diyl, oxirane-2,3-diyl cyclobutane-1,3-diyl, cyclopentane-1,4-diyl, bicyclo[1.1.1]pentane-1,3-diyl or cyclohexane-1,4-diyl; and/or d) one or more H atoms may be replaced, independently of one another, by F or CN; e) in the case of an alkyl or alkenyl radical containing asymmetric carbon atoms, the asymmetric carbon atoms have â€”CH3, â€”OCH3, â€”CF3, â€”F, â€”CN and/or â€”Cl as substituents; f) with the proviso that-only one of R1 and R2 is a hydrogen, F or CN; A1 and A2 are undirected and identical or different and are each phenylene-1,4-diyl, unsubstituted or monosubstituted or disubstituted by CN or F, phenylene-1,3-diyl, unsubstituted or monosubstituted or disubstituted by CN or F, cyclohexane-1,4-diyl, in which one or two H atoms may be replaced, independently of one another by CN, CH3 or F, 1-cyclohexene-1,4-diyl, in which one H atom may be replaced by F, pyridine-2,5-diyl, unsubstituted or monosubstituted by F, thiophene-2,5-diyl, unsubstituted or monosubstituted by F, furan-2,5-diyl or naphthalene-2,6-diyl, unsubstituted or monosubstituted or disubstituted by CN or F; M1 is undirected and is â€”OC(&boxH;O)â€”, â€”OCH2â€”, â€”SC(&boxH;O)â€” â€”SCH2â€” â€”CH2CH2â€”, â€”OC(&boxH;O)CH2CH2â€” â€”OCH2CH2CH2â€”, â€”Câ‰¡Câ€”, â€”(CH2)4â€” or a single bond; a is 0 or 1.