Patent ID: 7544803
Filing Date: 2009-06-09
Classification: C07D

Abstract:
1. A compound having the formula, or a pharmaceutically acceptable salt, wherein, P is selected from phenyl, heteroaryl or heterocyclyl; R R R R R R R Ar is aryl or heteroaryl, each of which may be optionally substituted by R Z is a bond, S, NR m is 0, 1 or 2; n is an integer value from 1 to 6; q and r are independently selected from 0, 1, 2 or 3; and s is 0, 1, 2 or 3; with the proviso that said compound of formula (I) is not a compound selected from: N-{3-[(N,N-Dimethylamino)methyl]-1,2,3,4-tetrahydro-7-quinolinyl}-4-biphenylcarboxamide; N-{3-[(N,N-Dimethylamino)methyl]-1-formyl-1,2,3,4-tetrahydro-7-quinolinyl}-4-biphenylcarboxamide; N-{1-Acetyl-3-[(N,N-dimethylamino)methyl]-1,2,3,4-tetrahydro-7-quinolinyl}-4-biphenylcarboxamide; N-{3-[(N,N-Dimethylamino)methyl]-1-methylsulfonyl-1,2,3,4-tetrahydro-7-quinolinyl}-4-biphenylcarboxamide; 5-methyl-N-quinolin-8-yl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-3 carboxamide; 5-methyl-N-quinolin-7-yl-1-[3-trifluoromethyl)phenyl]-1H-pyrazole-3-carboxamide; 5-methyl-N-quinolin-3-yl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-3-carboxamide; and 5-methyl-N-quinolin-5-yl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-3-carboxamide.