Patent ID: 8030311
Filing Date: 2011-10-04
Classification: A61P,C07D

Abstract:
1. A compound of the formula I, wherein each of R1 and R2, independently of the other, is selected from the group consisting of hydrogen, halo and C R3 is absent if Z is nitrogen or, if Z is C, then R3 is hydrogen, unsubstituted or substituted aryl or unsubstituted or substituted heterocyclyl; X is N (nitrogen) or CH (hydrogen-substituted carbon), Y is CH or N, Z is C or N, and Q is a moiety of the formula (A) or a moiety of the formula (B) where the asterisk * in formulae (A) and (B) marks the bond through which the moiety is bound to the NH of the amide group in formula I; and (a) each of R9 and R10, independently of the other, is selected from the group consisting of hydrogen, hydroxyl and C (b) R9 and R10 together represent oxo; or R1 and R9 together form a group —C(O)—CH2—or —CH2—CH2—, R2 is selected from the group consisting of hydrogen, halo and C or a pharmaceutically acceptable salt thereof.