Patent ID: 8969631
Filing Date: 2015-03-03
Classification: C07C,C07D

Abstract:
1. A method of preparing a chlorohydrin composition in which a polyhydroxy aliphatic hydrocarbon is reacted with a chlorination agent in the presence of a catalyst, the method comprises at least one combination of a series of unit operations comprising a first reaction step for reacting the polyhydroxy aliphatic hydrocarbon with the chlorination agent, a water removal step for separating a reaction mixture comprising water as a by-product discharged from the first reaction step into a water-rich layer and a water-deficient layer, and a second reaction step for reacting at least one constituent of the reaction mixture from which water is removed, with at least one of the chlorination agent and an additional chlorination agent, wherein these steps are performed in this stated order, and the method further comprises purifying the reaction mixture discharged from the final reaction step from among the plurarity of reaction steps to obtain a chlorohydrin concentrate, and mixing the water-rich layer, and the chlorohydrin concentrate, wherein the catalyst comprises at least one selected from the group consisting of an organic acid catalyst, a carboxylic acid-based catalyst, a nitrile-based catalyst, and a solid catalyst, wherein the reaction mixture discharged from the first reaction step, which is introduced into the water removal step, comprises the chlorination agent and water at a ratio of 10 to 25.0 parts by weight of the total of the chlorination agent and the additional chlorination agent and 75 to 90 parts by weight of water so that the reaction mixture discharged from the first reaction step, which is introduced into the water removal step, forms an azeotropic mixture.