Patent ID: 7847081
Filing Date: 2010-12-07
Classification: A61K,A61P,C07K,C12N

Abstract:
1. A nucleic acid encoding a fusion protein, the fusion protein comprising a first domain joined to one or more additional domains, wherein: (a) the first domain consists of an extracellular region and the nucleic acid segment encoding the extracellular region comprises a sequence that hybridizes over its full length, after a wash at 50° C. to 65° C. in a buffer containing 0.2×SSC and 0.1% SDS, to the complement of the portion of the nucleotide sequence set forth in SEQ ID NO:6 that encodes the amino acid sequence from cysteine at position 56 of SEQ ID NO:5 to the cysteine at position 130 of SEQ ID NO:5; and (b) the one or more additional domains each consists of an amino acid sequence that is unrelated to the polypeptide of SEQ ID NO:5.