Patent ID: 6699853
Filing Date: 2004-03-02
Classification: A01N,C07D

Abstract:
A 4-trifluoromethyl-3-oxadiazolylpyridine of the formula (Iâ€²), or a salt thereof, whereinm is 0 or 1; Xâ€² is a single bond, a straight-chain alkylene group having 1, 2 or 3 carbon atoms or a branched alkylene group having 3 to 9 carbon atoms, where one or more H atoms may be replaced by F; Yâ€² is â€”Oâ€”, â€”Sâ€”, â€”SO2â€”, â€”Oâ€”COâ€”, â€”Oâ€”COâ€”Oâ€”, â€”SO2â€”Oâ€”, â€”Oâ€”SO2â€”, â€”NR1â€”, â€”NR2â€”COâ€”, â€”NR3â€”COâ€”Oâ€”, â€”NR4â€”COâ€”NR5â€”, â€”Oâ€”COâ€”COâ€”Oâ€”, â€”Oâ€”COâ€”NR6â€”, â€”SO2â€”NR7â€” or â€”NR8â€”SO2â€”; R,R1,R2,R3,R4,R5,R6,R7,R8 are identical or different and are independently of one another H, (C1-C10)-alkyl, (C2-C10)-alkenyl, (C2-Cl10)-alkynyl, (C3-C8)-cycloalkyl, (C4-C8)-cycloalkenyl, (C6-C8)-cycloalkynyl, heterocyclyl or â€”(CH2)1-4-heterocyclyl, where each of the eight last-mentioned groups is unsubstituted or mono- or polysubstituted, and where, optionally R and R1, R and R2, R and R5, R and R6, R and R7, R and R8 or Xâ€² and R, together form a ring system, with the proviso, that the compounds in which Xâ€²=-, Yâ€²=O, R=H Xâ€²=-, Yâ€²=O, R=Me Xâ€²=-, Yâ€²=O, R=Et Xâ€²=-, Yâ€²=O, R=CHF2 Xâ€²=-, Yâ€²=O, R=CH2Ph Xâ€²=CH2, Yâ€²=O, R=2-furanyl Xâ€²=CH2, Yâ€²=O, R=Me Xâ€²=CH2, Yâ€²=O, R=5-isoxazolyl Xâ€²=CH2, Yâ€²=O, R=5-nitrofuran-2-yl Xâ€²=CH2CH2, Yâ€²=O, R=H Xâ€²=CH2CH2; Yâ€²=O, R=Me Xâ€²=CH2CH2, Yâ€²=O, Xâ€²=CH2CH2, Yâ€²=O, R=Et Xâ€²=CH2CH2, Yâ€²=O, Xâ€²=CH2CH2; Yâ€²=OC(O), R=4-F-phenyl Xâ€²=CH2CH2, Yâ€²=OC(O), R=2,6-difluorophenyl Xâ€²=CH2CH2, Yâ€²=OC(O), R=4-nitrophenyl Xâ€²=CH2CH2, Yâ€²=OC(O), R=t-Bu Xâ€²=CH2CH2, Yâ€²=OC(O), R=cyclopropyl Xâ€²=CH2CH2, Yâ€²=OC(O), R=Me Xâ€²=CH2CH2CH2, Yâ€²=O, R=H Xâ€²=-, Yâ€²=S(O), R=4-bromobenzyl Xâ€²=CH2, Yâ€²=S, R=Me Xâ€²=CH2, Yâ€²=S(O), R=Me Xâ€²=CH2, Yâ€²=S(O)2, R=t-Bu Xâ€²=CH2, Yâ€²=S, R=2-thienyl Xâ€²=CH2CH2, Yâ€²=S, R=Me Xâ€²=CH2CH2, Yâ€²=S, R=n-Pr Xâ€²=CH2CH2, Yâ€²=S, R=benzyl Xâ€²=CH2CH2, Yâ€²=S, R=2-thienylmethyl Xâ€²=CH2CH2CH2, Yâ€²=S, R=Me Xâ€²=CH2CH2CH2, Yâ€²=SO, R=Me Xâ€²=CH2CH2CH2CH2, Yâ€²=S, R=CH2CH2CH2CH2OMe are not included.