Patent ID: 7183273
Filing Date: 2007-02-27
Classification: A61K,A61P,C07D

Abstract:
1. A method to treat HIV or rheumatoid arthritis in a subject which method comprises administering to a subject in need of such treatment an effective amount of a compound of formula I or pharmaceutically acceptable acid addition salts, and any stereoisomeric forms and mixtures of stereoisomeric forms thereof: and optionally one or more agent useful in the treatment HIV; wherein, W is a nitrogen atom and Y is void or, W is a carbon atom and Y=H; R R Ar is an aromatic or heteroaromatic ring each optionally substituted at single or multiple, non-linking positions with electron-donating or withdrawing groups; n and n′ are independently, 0–2; X is a group of the formula: wherein, Ring A is an optionally substituted, saturated or unsaturated 5 or 6-membered ring, and P is an optionally substituted carbon atom, an optionally substituted nitrogen atom, sulfur or oxygen atom; wherein Ring B is an optionally substituted 5 to 7-membered ring; wherein Ring A or Ring B are bound to group W from any position through group V; wherein V is a chemical bond or V is a (CH wherein Z is selected from the group consisting of: a hydrogen atom; an optionally substituted C thereby treating HIV or rheumatoid arthritis in said subject.