Patent ID: 6200971
Filing Date: 2001-03-13
Classification: A61P,C07D

Abstract:
A bicyclic heterocyclic compound of the formula (I): ##STR258##in whichA represents a radical of the formula ##STR259##whereinL and M are identical or different and denote hydrogen, halogen, trifluoromethyl, carboxyl, cycloalkyl having 3 to 6 carbon atoms, hydroxyl, phenyl or straight-chain or branched alkyl, alkoxycarbonyl or alkoxy having in each case up to 6 carbon atoms,Q denotes a nitrogen atom or the --CH group,T denotes a group of the formula --SO.sub.2 or --CO or an oxygen or sulphur atom,D and E are identical or different and represent hydrogen, halogen, trifluoromethyl, hydroxyl or carboxyl, or represent straight-chain or branched alkyl, alkoxy or alkoxycarbonyl having in each case up to 6 carbon atoms,Z represents an oxygen or sulphur atom,R.sup.1 represents cycloalky having 3 to 10 carbon atoms, or represents straight-chain or branched alkyl having 1 to 10 carbon atoms, or represents phenyl, which is optionally substituted up to twice in an identical or different manner by halogen, nitro, cyano, hydroxyl or straight-chain or branched alkyl or alkoxy having in each case up to 4 carbon atoms,R.sup.2 represents hydrogen or straight-chain or branched alkyl having up to 3 carbon atoms,R.sup.3 represents hydrogen or straight-chain or branched alkyl having up to 5 carbon atoms, or represents cycloalkyl having 3 to 7 carbon atoms, or represents phenyl, or represents a 5- to 7- membered aromatic heterocyclic radical having up to 3 hetroatoms independently selected from the group consisting of S, N and O, which are optionally substituted up to 3 times in an identical or different manner by halogen, nitro, phenyl, or hydroxyl or by straight-chain or branched alkyl or alkoxy having up to 6 carbon atoms,R.sup.4 represents hydrogen, or represents a group of the formula --CH.sub.2 --OH or --CH.sub.2 O--CO--R.sup.11, whereinR.sup.11 denotes hydrogen, straight-chain or branched alkyl having up to 8 carbon atoms or phenyl, which is optionally substituted up to 3 times in an identical or different manner by halogen, hydroxyl, cyano or straight-chain or branched alkyl or alkoxy having in each case up to 4 carbon atoms,or a salt thereof.