Patent ID: 8859211
Filing Date: 2014-10-14
Classification: G01N

Abstract:
1. A method for the analysis of a sample comprising one or more proteins, wherein the sample is selected from the group consisting of blood serum and urine, the method comprising the steps of: a. separating a first portion of the sample by electrophoresis into constituent parts; b. mixing a second portion of the sample with a binding partner for a target compound or a group of target compounds, wherein the target compound or the group of the target compounds comprise an immunoglobulin, and the binding partner is a macromolecule comprising: c. separating the second portion by electrophoresis into constituent parts, wherein a protein or proteins of the sample that have not produced a complex with the binding partner are separated from the complex of the binding partner with the target compound or the group of the target compounds in a separation medium in which the binding partner has a net negative charge and wherein a non-complexed binding partner and the complex of the binding partner with the target compound or the group of the target compounds are migrated out of protein bands; d. comparing the separated constituent parts of step (a) with the separated constituent parts of step (c).