Patent ID: 7560435
Filing Date: 2009-07-14
Classification: A61K,A61P

Abstract:
1. A method of treatment of a human patient suffering from a B-cell lymphoproliferative disorder, comprising administering a therapeutically effective amount of a compound of formula (I), or a pharmaceutically acceptable solvate or addition salt thereof, together with appropriate amounts of pharmaceutically acceptable diluents or carriers; wherein, —R 2 , —R 3 and —R 5 are radicals independently selected from the group consisting of —H, PO(OH) 2 , PO(OH)—O—PO(OH) 2 , PO(OH)—O—PO(OH)—O—PO(OH) 2 , CO—R′ and CO—OR′; R′ being a hydrocarbyl radical up to twelve carbon atoms, which may be aliphatic including alkyl, alkenyl, and alkynyl groups and groups which have a mixture of saturated and unsaturated bonds, alicyclic, aryl or a combination thereof; wherein R′ may be a radical from a straight-chain, a branched-chain, a cycle or a combination thereof; —R′ may have one or more hydrogen atoms substituted by one or more halogen atoms, and/or by one or more (C 1 -C 4 )-alkyl groups; R′ may have one or more CH 2 groups substituted by one or more NH, O and/or S groups; and R′ may have one or more CH groups substituted by one or more N atoms