Patent ID: 8999708
Filing Date: 2015-04-07
Classification: A61P,C07K,C12N,C12Q

Abstract:
1. An isolated nucleic acid encoding at least the heavy and/or light variable region(s) of the antibody or protein with an antigen-binding portion of an antibody, comprising a variable heavy chain amino acid sequence comprising an HCDR1 sequence of SEQ ID NO:1, an HCDR2 sequence of SEQ ID NO:2, an HCDR3 sequence of SEQ ID NO:3 and a variable light chain amino acid sequence comprising an LCDR1 sequence of SEQ ID NO:4, an LCDR2 sequence of SEQ ID NO:5 and an LCDR3 sequence of SEQ ID NO: 6, wherein said antibody or protein binds to the IL12Rβ1 polypeptide of SEQ ID NO:89.