Patent ID: 6252060
Filing Date: 2001-06-26
Classification: A61K,B82Y,C07H

Abstract:
A conjugate of dideoxyguanosine and at least one lipid moiety selected from the group consisting of mono- or diacylglycerols, mono- or dialkylglycerols, 1 -acyl-2-alkylglycerols, 1 -alkyl-2-acylglycerols, sphingolipids, fatty alcohols, ceramides, and 1,2-acyl, 1,2-alkyl or acyl/alkyl substituted oxypropyl(dimethyl)-.beta.-hydroxyethyl ammonium, said lipid moiety being covalently linked to said dideoxyguanosine through a monophosphate linkage, through an ester or thioester bond, to an available functional group at the 5'-carbon of the pentose group of said dideoxyguanosine.