Patent ID: 7825225
Filing Date: 2010-11-02
Classification: A61K,A61P,C07K

Abstract:
1. A monoclonal antibody that binds to an epitope of the lipopolysaccharide (LPS) inner core of a galE mutant of an immunotype L3 strain of Neisseria meningitidis , wherein the LPS inner core epitope comprises a phosphoethanolamine moiety linked to the 3-position of HepII of the LPS inner core, wherein said monoclonal antibody binds to the LPS inner core of L1, L3, L7, L8, L9, L10, L11 and L12 immunotypes of Neisseria meningitidis , but not the LPS inner core of L2, L4, L5 and L6 immunotypes of Neisseria meningitidis , wherein the monoclonal antibody is the monoclonal antibody B5 produced by the hybridoma deposited with the accession number IDAC 260900-1.