Patent ID: 6180618
Filing Date: 2001-01-30
Classification: A61P,C07J

Abstract:
A compound of formula (I) ##STR41##wherein:GS is a bile acid group of the formula ##STR42##R.sup.1 is a bond to X or OH;R.sup.2 is a bond to X, --OH, --O--(C.sub.1 -C.sub.6)-alkyl, --NH--(C.sub.2 -C.sub.6)-alkyl-SO.sub.3 H, --N(CH.sub.3)--CH.sub.2 --CH.sub.2 --SO.sub.3 H, --NH--(C.sub.1 -C.sub.6)-alkyl-COOH, or --N(CH.sub.3)--(C.sub.1 -C.sub.6)-alkyl-COOH;with the proviso that R.sup.1 and R.sup.2 can not simultaneously be a bond to X;R.sup.3, R.sup.4 each independently of one another is H or OH; ##STR43##or a bond;l, m, n each independently of one another is 0 or 1;L is --(C.sub.1 -C.sub.6)-alkyl or phenyl;AA.sup.1, AA.sup.2 each independently of one another is an amino acid radical or an amino acid radical which is mono or polysubstituted by an amino acid-protective group;or a pharmaceutically tolerated salt thereof.