Patent ID: 7776884
Filing Date: 2010-08-17
Classification: C07C,C07D

Abstract:
1. A compound of Formula (I) or a stereoisomer or a pharmaceutically acceptable salt thereof, wherein: ring B is a heterocycle of 3 to 7 atoms wherein the heterocycle is saturated or partially unsaturated, the heterocycle containing a heteroatom selected from —O—, —S—, —S(═O)—, —S(═O) Z is selected from a bond, —C(O)—, —C(O)NH—, —C(S)NH—, —SO E is selected from —S(O) R R R R R R R R R R R R R R R R R R R R R, at each occurrence, is selected from H, C R alternatively, two R R R R R R R R alternatively, two R R R R R R R R′, at each occurrence, is selected from H, C R R alternatively, R R R R R R R R R R R R R R R R R R R R n is selected from 1 and 2; m is selected from 0 and 1; p, at each occurrence, is independently selected from 0, 1, and 2; q, at each occurrence, is independently selected from 1, 2, 3, and 4; r, at each occurrence, is independently selected from 0, 1, 2, 3, and 4; s, at each occurrence, is independently selected from 0 and 1; and t, at each occurrence, is independently selected from 2, 3, and 4.