Patent ID: 8269044
Filing Date: 2012-09-18
Classification: C07C,C07D

Abstract:
1. A method for producing a primary amine compound represented by the formula (3): wherein Ar is as defined below, which comprises reacting a halogen compound represented by the formula (1): wherein Ar represents an aromatic group selected from the group consisting of a phenyl group, a naphthyl group, a pyridyl group, a furyl group, a thienyl group, a pyrrolyl group, an oxazolyl group, an isoxazolyl group, an isothiazolyl group, an imidazolyl group, a pyrazolyl group, a pyridazinyl group, a pyrimidinyl group, a pyrazinyl group, a quinolinyl group, a quinoxalinyl group and a benzimidazolyl group, and said Ar may have 1 to 3 substituents which may be the same or different and are independently a halogen atom, a lower alkyl group, a lower alkoxy group, a lower alkylenedioxy group, a nitro group, a cyano group or a di(lower alkyl amino group, and X represents a halogen atom, with ammonia and formaldehyde in an alcohol solvent to obtain a hexahydrotriazine compound represented by the formula (2) : wherein Ar is as defined above, and subjecting the hexahydrotriazine compound represented by the formula (2) to a decomposition treatment; and wherein the decomposition treatment is conducted by reacting the hexahdrotrazine compound represented by the formula (2) with hydroxylamine under an acidic condition, and wherein 1 to 10 moles of formaldehyde is used per mole of the halogen compound represented by the formula (1).