Patent ID: 6331618
Filing Date: 2001-12-18
Classification: C12N,C12Q

Abstract:
An aqueous comnposition comprising a nucleic acid analog with an uncharged, neutral backbone and about 5% (v/v) to about 95% (v/v) of a polar aprotic solvent, wherein the concentration of the nucleic acid analog is in the range of about 1 .mu.M to about 10 mM and the composition has a pH in the range of about pH 5 to about pH 9; andwherein the polar aprotic solvent is selected from the group consisting of: ##STR6##where X is O, NH, or NP.sub.2 ; R.sub.1 is alkyldiyl; and each R.sub.2 is independently selected from the group consisting of methyl, cycloalkyl, alkyl, and aryl.