Patent ID: 6391289
Filing Date: 2002-05-21
Classification: A61K,A61P,A61Q

Abstract:
A method for protecting human skin or human hair against solar rays, comprising application, to the human skin or human hair to be protected, of an effective amount of a cosmetic or pharmaceutical preparation of sunscreen combinations comprisingA) compounds absorbing essentially in the UV-A region and B) further compounds absorbing in the UV-A region, in the UV-B region and over both regions, where the constituents absorbing in the UV-A region comprise effective amounts of at least A) one 4,4â€²-diarylbutadiene of the formula I in whichR1 and R2 independently of one another are hydrogen, C1â€”C20-alkyl, C3â€”C10-cycloalkyl or C3â€”C10-cycloalkenyl, and as compoundsB) comprise effective amounts of at least one compound chosen from the group consisting of Ba) dibenzoylmethane compounds of the formula III in whichR3 is C1â€”C12-alkyl and R4 is hydrogen, C1â€”C12-alkyl or C1â€”C12-alkoxy, Bb) triazine derivatives of the formula IV in whichR5 to R7 independently of one another are optionally substituted C1â€”C20-alkyl, C5â€”C10-aryl, C5â€”C10-heteroaryl or SpSil, where Sp is a spacer and Sil is a silane, oligosiloxane or polysiloxane radical, X is the divalent radical whereR8 is hydrogen or optionally substituted C1â€”C20-alkyl, C5â€”C10-aryl or C5â€”C10-heteroaryl, Bc) triazine derivatives of the formula V in which at least one o-hydroxyl group and at least one p-alkoxy group having 1 to 20 carbon atoms are bonded to the phenyl rings,Bd) the benzotriazole derivative of the formula VI Be) the benzimidazole derivative of the formula VII Bf) the benzotriazole derivative of the formula VIII Bg) o,oâ€²,p,pâ€²-tetrahydroxybenzophenone of the formula IX Bh) an organosiloxane benzalmalonate of the formula Xa in whichV1â€² is the group V1 is a methyl group or V1â€², or of the formula Xb in which V2â€² is the group of the structure V2 is a methyl group or V2â€², or mixtures of compounds of the formulae Xa and Xb, where t is a value up to 100 and u is a value up to 20, with the proviso that u=0 when V1=V1â€² and/or V2=V2â€², and u is a value from 1 to 20,when V1=CH3 and/or V2=CH3, as photostable UV filters, optionally together with further compounds which absorb in the UV region and which are known per se for cosmetic and pharmaceutical preparations.