Patent ID: 9151749
Filing Date: 2015-10-06
Classification: B01L,G01N

Abstract:
1. An assay device for determining the presence and/or amount of an analyte of interest in a liquid sample applied, or otherwise introduced, to the device, the device comprising: at least one assay flow path along which a liquid flows; an accumulation zone comprising means for retaining a labelled reagent in an analyte-dependent manner; a gas generating means which generates a gas dependent upon the presence, absence or amount of analyte, the gas-generating means including the labelled reagent; wherein the gas creates one or more bubbles in the liquid sample which acts to alter the flow of liquid along the flow path to a downstream zone; a bubble-retaining means upstream from said downstream zone which facilitates the trapping of gas bubbles in the flow path to reduce or stop flow of liquid therealong; and a detection means to detect any alteration in flow of liquid and/or an indicator means to detect the presence or arrival of liquid at the downstream zone; wherein an assay result is determined by detecting the alteration of flow of liquid along the flow path and/or by detecting the presence or arrival of liquid at the downstream zone.