Patent ID: 9162011
Filing Date: 2015-10-20
Classification: A61K,A61L

Abstract:
1. A soft tissue matrix composition for use in a patient treatment prepared by a method consisting of: providing a human soft tissue material; processing the human soft tissue material to mechanically disrupt the extracellular matrix collagen or macrostructure and partially disrupt the collagen microfibrillar architecture by a process selected from the group consisting of: (i) cryofracturing the human soft tissue material; (ii) cryofracturing and washing the human soft tissue material; (iii) cryofracturing and triturating the human soft tissue material; and (iv) cryofracturing, triturating, and washing the human soft tissue material, wherein the processed tissue material is in a partially hydrated state, the partial hydration comprising a substantial amount of the natural interstitial water of the human soft tissue material.