Patent ID: 7537703
Filing Date: 2009-05-26
Classification: B01J,G01N

Abstract:
1. A method of the production of a packing material for liquid chromatography which comprises chemically modifying silica gel with a bifunctional silane compound represented by the general formula [I]: [wherein, X 1 and X 2 , the same or different, represent a hydrogen atom, a halogen atom or an alkoxy group having 1 to 4 carbon atoms; and R 1 represents an alkyl group or an aryl group which can have substituent(s)], and carrying out an endcapping reaction of the resulting chemically modified silica gel using bifunctional cyclic silazane represented by the general formula [II]: [wherein, R 2 and R 3 , the same or different, represent an alkyl group having 1 to 4 carbon atoms; and n represents a value indicating unit number that forms the ring, which is an integer of 2 to 10].