Patent ID: 7312194
Filing Date: 2007-12-25
Classification: A61K,C07H

Abstract:
1. A compound of general Formula I, which is an ionic complex: in which D is a therapeutically useful molecule selected from the group consisting of a drug, peptide, protein, nucleic acid, mono- or oligosaccharide, and sugar-peptide conjugate; r is an integer greater than or equal to 1; p, n and m may be the same or different, and are independently integers greater than or equal to 1; n and m represent the overall magnitude of the charge on the molecules; and z and y are charges, either positive (+) or negative (−), such that when z is positive, y is negative and vice versa; and is a carrier compound, in which X is a covalent bond, or is a linker group, selected from 2 to 14 atom spacers, which may be optionally substituted, branched or linear; S is a mono- or oligosaccharide; L is a lipidic moiety; W is a 3 to 10 atom alkyl or heteroalkyl spacer, which may be branched or linear, and is substituted with one or more functional groups, each of which is charged or is capable of carrying a charge under physiological conditions; and q is an integer, which ranges from 3 to the number of hydroxyls available for substitution on the mono- or oligosaccharide.