Patent ID: 8476241
Filing Date: 2013-07-02
Classification: A61K,A61P,C07H,G01N

Abstract:
1. A method for treating esophogeal adenocarcinoma in a mammal comprising treating the mammal with an effective amount of a compound of the formula: wherein each R2′, R3′ and R5′ are independently hydrogen, optionally substituted phosphate or phosphonate; acyl; alkyl; amide; sulfonate ester; sulfonyl, methanesulfonyl, benzylsulfonyl, arylsulfonyl, wherein the phenyl group is optionally substituted with one or more substituents; a lipid; a phospholipid; an amino acid; a carbohydrate; a peptide; or cholesterol; or other pharmaceutically acceptable leaving group that, in vivo, provides a compound wherein R2′, R3′ or R5′ is independently H or mono-, di- or tri-phosphate; wherein R wherein R