Patent ID: 8927760
Filing Date: 2015-01-06
Classification: A61K,A61P,C07C

Abstract:
1. The colchicine derivative or the pharmaceutically acceptable salt thereof, the derivative being selected from the group consisting of: (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid benzyl ester; (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 4-methoxy benzyl ester; (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 4-isopropyl benzyl ester; (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 9H-fluoren-9-ylmethyl ester; (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 1-methyl-9H-fluoren-9-ylmethyl ester; (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 2,7-di-tert-butyl-9H-fluoren-9-ylmethyl ester; and (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 2-(9H-fluoren-9-yl)-ethyl ester.