Patent ID: 7381418
Filing Date: 2008-06-03
Classification: A61K,A61P

Abstract:
1. An implantable or insertable medical device comprising (a) a therapeutic agent and (b) a polymeric release region that controls the release of said therapeutic agent upon administration to a patient, wherein said polymeric release region comprises a radiation-crosslinked methylene containing copolymer that comprises an unsaturated hydrocarbon monomer and an additional monomer selected from halogenated unsaturated hydrocarbons, acrylic momomers, alkyl vinyl ethers, cyclic ethers, unsaturated ester monomers, ethylene adipate, tetramethylene adipate, ethylene malonate, vinyl acetate, vinyl propionate, vinyl trifluoroacetate, ε-caprolactone, 1-vinyl-2-pyrrolidone and methyl styrene, and wherein said polymeric release region is crosslinked with a radiation dose of at least 10,000 rads.