Patent ID: 7097986
Filing Date: 2006-08-29
Classification: A61K,A61P,C07K,Y10S

Abstract:
1. A method for imaging of lymphatic vasculature in tissue, comprising the step of contacting the tissue with a monoclonal antibody selected from the group consisting of 2F8 (ATCC No. PTA-3653), 4A5 (ATCC No. HB-12698), 4E10 (ATCC No. PTA-3652), and 5F12 (ATCC No. PTA-3651 or a F(ab′)2, F(ab′), F(ab) fragment or a chimeric antibody thereof which interferes with binding of VEGF-D to a VEGF receptor-3, and detecting the occurrence of binding of said antibody to VEGF-D wherein the binding of said antibody is indicative of an image of the lymphatic vasculature in said tissue.