Patent ID: 8660801
Filing Date: 2014-02-25
Classification: C12Q,G16B,G16H

Abstract:
1. A method of treating a subject having a breast tumor, the method comprising: determining expression levels of signature genes comprising Androgen receptor (AR); Jun oncogene (c-Jun); Signal transducer and activator of transcription 1 (STAT1); Protein kinase C, beta (PRKCB or PKC); V-rel reticuloendotheliosis viral oncogene homolog A (avian) (RELA or p65); c-Abl oncogene 1, receptor tyrosine kinase (ABL1 or c-Abl); SMT3 suppressor of mif two 3 homolog 1 ( assigning a radiation sensitivity index to the tumor based on expression levels of the signature genes; selecting a treatment regimen for the subject based on the radiation sensitivity index; and administering the selected treatment to the subject.