Patent ID: 6451290
Filing Date: 2002-09-17
Classification: A61K,A61Q

Abstract:
A chewing gum for remineralizing subsurface lesions and/or for mineralizing exposed dentin tubles in teeth, comprising:(a) a cationic component comprising at least one partially water-soluble calcium salt; (b) an anionic component comprised of at least one water-soluble phosphate salt; and (c) a separating component for separating said components (a) and (b), said separating component comprising a water-insoluble gum base, said gum base being capable of releasing said components (a) and (b) into water and/or saliva when said chewing gum is mixed with said water and/or saliva; wherein said components (a) and (b) have a pH in water such that a mixed aqueous composition formed by mixing said components (a) and (b) with said water and/or saliva has a pH of from about 4.0 to about 10.0; further wherein said cationic component comprises an amount of said calcium salt such that in said mixed aqueous composition a first portion of said calcium salt exists as dissolved calcium cations and a second portion of said calcium salt exists as undissolved calcium salt, said anionic component comprising an amount of said phosphate salt such that said mixed aqueous composition further comprises dissolved phosphate anions released by said phosphate salt.