Patent ID: 8435753
Filing Date: 2013-05-07
Classification: B82Y,G01N

Abstract:
1. A tissue differentiation method based on surface enhanced Raman scattering, which enables rapid tissue identification and enables determining, during surgery, an area where a cancerous tissue is located; the method comprising the steps of: preparing synthesized silver and/or gold nanoparticles, in which silver and/or gold colloidal solutions are used, by concentrating ( cutting a few millimeters from a plurality of obtained tissue samples ( placing the plurality of cut tissue samples in a porcelain container ( adding 3-5 ml of liquid nitrogen or argon into the container and completely freezing the cut tissue samples ( crushing the frozen tissue sample by pressing with a solid object and bringing the frozen tissue sample to a liquefied mixture ( adding a part of the silver/and or gold nanoparticles directly into the liquefied tissue mixture ( transferring a small portion of the mixture sample onto a surface on which measurement will be performed ( drying the mixture sample at room temperature ( performing a measurement with a Raman device (