Patent ID: 6365135
Filing Date: 2002-04-02
Classification: A61K,A61P,A61Q

Abstract:
A depigmenting or bleaching composition, comprising, in a cosmetically and/or dermatologically acceptable medium, at least one aminophenol amide derivative represented by formula (I): in which:R represents a hydrogen atom; a linear, branched or cyclic, saturated or unsaturated C1-C24 alkyl group optionally hydroxylated with one or more hydroxyl functions; an aryl group, which may or may not be substituted with one or more functions selected from the group consisting of: â€”OH; â€”NH2; â€”COOH; â€”NO2; and â€”OR5 wherein R5=C1-C24 alkyl; â€”COOR6 wherein R6=C1-C24 alkyl; â€”NR7R8, wherein R7=H or C1-C24 alkyl, R8=H or C1-C24 alkyl; a group â€”COR9, wherein R9 represents a linear, branched or cyclic, saturated or unsaturated C1-C24 alkyl group optionally hydroxylated with one or more hydroxyl functions, an aryl group which may or may not be substituted with one or more functions selected from the group consisting of â€”OH, â€”NH2, â€”COOH, â€”NO2, â€”OR5, â€”COOR6, â€”NR7R8, wherein R5, R6, R7 and R8 are as defined above; R1, and R2, which may be identical or different, represent a group selected from the group consisting of: a hydrogen atom; a linear, branched or cyclic, saturated or unsaturated C1-C24 alkyl group optionally hydroxylated with one or more hydroxyl functions; an aryl group which may or may not be substituted with one or more functions selected from the group consisting of â€”OH, â€”NH2, â€”COOH, â€”NO2, â€”OR5, â€”COOR6, â€”NR7R8, wherein R5, R6, R7 and R8 are as defined above; and a group selected from the group consisting of: â€”OH; â€”OQ1; â€”COQ2; â€”COOQ3; â€”NQ4Q5; â€”CONQ6Q7; â€”SQ8; â€”CH2OQ9; wherein Q1, Q2, Q3, Q4, Q5, Q6, Q7, Q8 and Q9 are a member selected from the group consisting of a hydrogen atom; linear, branched or cyclic, saturated or unsaturated C1-C24 alkyl groups optionally substituted with one or more hydroxyl groups; aryls which may or may not be substituted with one or more functions selected from the group consisting of: â€”OH, â€”NH2, â€”COOH, â€”NO2, â€”OR5, â€”COOR6, and â€”NR7R8, wherein R5, R6, R7 and R8 are as defined above; amino acid residues and cyclic or non-cyclic carbohydrate residues; R3 and R4, which may be identical or different, represent a radical selected from the group consisting of: a hydrogen atom; linear or branched, saturated or unsaturated C1-C24 alkyl groups optionally substituted with one or more hydroxyl groups; cyclic, saturated or unsaturated C1-C24 alkyl groups; aryls which may or may not be substituted with one or more functions selected from the group consisting of: â€”OH, â€”NH2, â€”NO2, â€”OR5, â€”COOR6, â€”NR7R8, wherein R5, R6, R7 and R8 are as defined above; with the exception of the compound corresponding to the formula (I) for which R=R1=R2=R3=H, R4=CH3, the OH group being placed in the para position relative to the amide.