Patent ID: 7777083
Filing Date: 2010-08-17
Classification: C07C

Abstract:
1. A method for the reduction of compounds comprising one or more carbon-oxygen (C═O) double bonds comprising contacting the compound with hydrogen gas and a catalyst comprising an iridium aminodiphosphine complex and a base, wherein the hydrogen gas is used at a pressure greater than 3 atm and the complex is of the formula (II): wherein X may be the same or different and are selected from hydrogen and any anionic ligand; [P in which R 3 to R 6 simultaneously or independently are selected from of H, C 1-20 alkyl, C 2-20 alkenyl, C 3-20 cycloalkyl and aryl, said latter 4 groups being optionally substituted, or two adjacent or geminal R 3 , R 4 , R 5 or R 6 groups are bonded together to form an optionally substituted ring; x and y are, simultaneously or independently, equal to 0, 1, 2, 3 or 4; and R is simultaneously or independently selected from H, C the optional substituents are selected from one or more of halo, OH, NH R