Patent ID: 6221887
Filing Date: 2001-04-24
Classification: A61K,A61P

Abstract:
A method of treating or preventing inflammatory disorders in a mammal in need thereof, which comprises administering to the mammal a compound having NMDA receptor antagonist activity or sodium channel antagonist activity or a metabolite and/or pharmaceutically acceptable salt thereof and wherein the compound is a compound of formula (I): ##STR3##whereinR.sup.1 is Pyridyl, phenyl or 4-fluorophenyl;R.sup.2 is phenyl or 4-fluorophenyl;R.sup.3 is hydrogen, C.sub.1-6 alkyl or methoxycarbonyl;R.sup.4 is hydrogen or methyl; andR.sup.5 is hydrogen or COCH.sub.2 NH.sub.2.