Patent ID: 6087154
Filing Date: 2000-07-11
Classification: C07K,C12N

Abstract:
An isolated nucleic acid compound encoding a rhesus receptor having affinity for neuropeptide Y, pancreatic polypeptide, peptide YY, said receptor having the amino acid sequence:Met Asn Ser Thr Leu Phe Ser Gln Val Glu Asn His Ser 1 5 10 - Val His Ser Asn Phe Ser Glu Lys Asn Ala Gln Leu Leu 15 20 25 - Ala Phe Glu Asn Asp Asp Cys His Leu Pro Leu Ala Met 30 35 - Ile Phe Thr Leu Ala Leu Ala Tyr Gly Ala Val Ile Ile 40 45 50 - Leu Gly Val Ser Gly Asn Leu Ala Leu Ile Ile Ile Ile 55 60 65 - Leu Lys Gln Lys Glu Met Arg Asn Val Thr Asn Ile Leu 70 75 - Ile Val Asn Leu Ser Phe Ser Asp Leu Leu Val Ala Ile 80 85 90 - Met Cys Leu Pro Phe Thr Phe Val Tyr Thr Leu Met Asp 95 100 - His Trp Val Phe Gly Glu Ala Met Cys Lys Leu Asn Pro 105 110 115 - Phe Val Gln Cys Val Ser Ile Thr Val Ser Ile Phe Ser 120 125 130 - Leu Val Leu Ile Ala Val Glu Arg His Gln Leu Ile Ile 135 140 - Asn Pro Arg Gly Trp Arg Pro Asn Asn Arg His Ala Tyr 145 150 155 - Val Gly Ile Ala Val Ile Trp Val Leu Ala Val Ala Ser 160 165 - Ser Leu Pro Phe Leu Ile Tyr Gln Val Met Thr Asp Glu 170 175 180 - Pro Phe Gln Asn Val Thr Leu Asp Ala Tyr Lys Asp Lys 185 190 195 - Tyr Val Cys Phe Asp Gln Phe Pro Ser Asp Ser His Arg 200 205 - Leu Ser Tyr Thr Thr Leu Leu Leu Val Leu Gln Tyr Phe 210 215 220 - Gly Pro Leu Cys Phe Ile Phe Ile Cys Tyr Phe Lys Ile 225 230 - Tyr Ile Arg Leu Lys Arg Arg Asn Asn Met Met Asp Lys 235 240 245 - Met Arg Asp Asn Lys Tyr Arg Ser Ser Glu Thr Lys Arg 250 255 260 - Ile Asn Ile Met Leu Leu Ser Ile Val Val Ala Phe Ala 265 270 - Val Cys Trp Leu Pro Leu Thr Ile Phe Asn Thr Val Phe 275 280 285 - Asp Trp Asn His Gln Ile Ile Ala Thr Cys Asn His Asn 290 295 - Leu Leu Phe Leu Leu Cys His Leu Thr Ala Met Ile Ser 300 305 310 - Thr Cys Val Asn Pro Ile Phe Tyr Gly Phe Leu Asn Lys 315 320 325 - Asn Phe Gln Arg Asp Leu Gln Phe Phe Phe Asn Phe Cys 330 335 - Asp Phe Arg Ser Arg Asp Asp Asp Tyr Glu Thr Ile Ala 340 345 350 - Met Ser Thr Met His Thr Asp Val Ser Lys Thr Ser Leu 355 360 - Lys Gln Ala Ser Pro Val Ala Phe Lys Lys Ile Asn Asn 365 370 375 - Asp Asp Asn Glu Arg Ile * 380 which is SEQ ID NO:2.