Patent ID: 6376256
Filing Date: 2002-04-23
Classification: B01J,C40B,Y10T

Abstract:
A process for arraying beads for bead-based combinatorial libraries which comprises:establishing a bead-receiving surface comprising a pattern of discrete bead attachment areas, wherein each discrete bead attachment area is an area of adhesive on a porous substrate, each bead attachment area being capable of holding a limited number of beads of uniform size, and an area, from which beads are free to separate, spacing the discrete bead attachment areas from one another, the limited number of beads for each bead attachment area being the same as that for every other bead attachment area in the pattern; placing a mixture of beads of uniform size onto the surface; causing a predetermined number of beads from the mixture to attach to each of the discrete bead attachment areas; removing from the surface beads which are not attached to the discrete bead attachment areas; and thereafter releasing the attached beads from the discrete bead attachment areas by washing the porous substrate with a solvent and thereby dissolving the bead attachment areas, and depositing them in an array of receptacles.