Patent ID: 7332486
Filing Date: 2008-02-19
Classification: A61P,C07D

Abstract:
1. A compound of Formula I: wherein, R  alkyl having 1 to 5 carbon atoms, which is unsubstituted or substituted one or more times by halogen, hydroxy, or combinations thereof, and wherein a —CH  cycloalkyl having 3 to 6 carbon atoms, or  cycloalkylalkyl having 4 to 7 C atoms; R  arylalkyl having 7 to 16 carbon atoms, which is unsubstituted or substituted one or more times by halogen, C  heteroaryl having 5 to 10 ring atoms in which at least 1 ring atom is a heteroatom, which is substituted one or more times by halogen, aryl having 6 to 14 carbon atoms, C  heteroarylalkyl wherein the heteroaryl portion has 5 to 10 ring atoms in which at least 1 ring atom is a heteroatom and the alkyl portion has 1 to 3 carbon atoms, the heteroaryl portion is unsubstituted or is substituted one or more times by halogen, aryl having 6 to 14 carbon atoms, C R  cycloalkylalkyl having 4 to 12 C atoms, which is unsubstituted or substituted one or more times by C  aryl having 6 to 14 carbon atoms, which is unsubstituted or substituted one or more times by halogen, C  heteroaryl having 5 to 10 ring atoms in which at least 1 ring atom is a heteroatom, which is unsubstituted or substituted one or more times by halogen, aryl having 6 to 14 carbon atoms, C  C  C R R  cycloalkyl having 3 to 8 carbon atoms, which is unsubstituted or substituted one or more times by halogen, C  cycloalkylalkyl having 4 to 12 C atoms, which is unsubstituted or substituted one or more times by C  aryl having 6 to 14 carbon atoms which is unsubstituted or substituted one or more times by halogen, C  arylalkyl having 7 to 16 carbon atoms, which is unsubstituted or substituted one or more times by halogen, C  heteroaryl having 5 to 10 ring atoms in which at least 1 ring atom is a heteroatom, which is unsubstituted or substituted one or more times by halogen, aryl having 6 to 14 carbon atoms, C  heteroarylalkyl wherein the heteroaryl portion has 5 to 10 ring atoms in which at least 1 ring atom is a heteroatom and the alkyl portion has 1 to 3 carbon atoms, the heteroaryl portion is unsubstituted or is substituted one or more times by halogen, aryl having 6 to 14 carbon atoms, C  heterocycle having 5 to 10 ring atoms in which at least 1 ring atom is a heteroatom, which is unsubstituted or is substituted one or more times by halogen, aryl having 6 to 14 carbon atoms, C  heterocycle-alkyl wherein the heterocycle portion has 5 to 10 ring atoms in which at least 1 ring atom is a heteroatom and the alkyl portion has 1 to 3 carbon atoms, the heterocycle portion is nonaromatic and is unsubstituted or is substituted one or more times by halogen, aryl having 6 to 14 carbon atoms, C or a pharmaceutically acceptable salt thereof.