Patent ID: 6384090
Filing Date: 2002-05-07
Classification: A61K,B01F,B01J,C07C,C09B,Y02P,Y10S

Abstract:
A process for preparing an active ingredient dispersion which comprises:i) dissolving an active ingredient in a supercritical fluid gas to form a supercritical fluid gas solution of the active ingredient, ii) dispersing the supercritical fluid gas solution of the active ingredient in a gas-saturated liquid to form a first dispersion of the liquid and the supercritical fluid gas solution, wherein the gas saturating the liquid is the same as the gas utilized in supercritical fluid form for dissolving the active ingredient, iii) passing the first dispersion through a holdup section to form a second dispersion of the liquid comprising the active ingredient and the supercritical fluid gas, iv) separating the second dispersion without previous decompression into the gas phase and a third dispersion of the liquid and the active ingredient, and v) recycling a part of the third dispersion to step (ii).