Patent ID: 6235747
Filing Date: 2001-05-22
Classification: A61P,C07D

Abstract:
A compound of the formula ##STR10##and the pharmaceutically acceptable salts thereof, whereinR.sup.1 and R.sup.2 form, together with the nitrogen to which they are attached, an azabicyclic ring containing from 6 to 14 ring members, from 1 to 3 of which are nitrogen and the rest of which are carbon;n is 0,1 or 2; and each carbon of said (CH.sub.2).sub.n can optionally be substituted with a substituent R.sup.8 ;m is 0,1, or 2; and each carbon of said (CH.sub.2).sub.m can optionally be substituted with a substituent R.sup.9 ;each R.sup.8 and each R.sup.9 is selected, independently, from (C.sub.1 -C.sub.4)alkyl, aryl-(C.sub.1 -C.sub.4)alkyl wherein said aryl is selected from phenyl and naphthyl; allyl and phenallyl;X and Y are selected, independently, from methyl, methoxy, hydroxy and hydrogen; andR.sup.10 is hydrogen or (C.sub.1 -C.sub.6) alkyl;with the proviso that R.sup.8 is absent when n is zero and R.sup.9 is absent when m is zero;or a pharmaceutically acceptable salt of such compound.