Patent ID: 7618650
Filing Date: 2009-11-17
Classification: A61K,A61P

Abstract:
1. A combination comprising at least one short acting hypnotic agent selected from the group consisting of zolpidem, zopiclone, eszopiclone, zaleplon, ramelteon, triazolam, etizolam, brotizolam and indiplon, and a compound defined by formula I, an enantiomer, a stereoisomer, a tautomer or a pharmaceutically acceptable salt thereof: wherein: X═Y denotes either a single or double bond between X and Y; X is CR, N, or O; Y is CR, CHR, CO, or N; Z is NR; A, B and E are the same or different and independently from each other are CR; D is CH Ar is substituted or unsubstituted phenyl or furan; each R is independently chosen from hydrogen, halogen, CN, or C R R the substituents are selected from the group consisting of substituted or unsubstituted phenyl, C