Patent ID: 6019896
Filing Date: 2000-02-01
Classification: C12N,C12Q,G01N

Abstract:
A method of analyzing a biochemical sample, comprising:in a separation run, separating the sample into its constituent components thereby producing separation data representing detection of a signal indicative of a physical property associated with the components as a function either of time or of distance along a separation path, the separation data having a plurality of sample peaks;separating a co-migrating standard having constituents of known physical properties thereby introducing reference peaks into the separation data;based on the separation data, computing a quality metric indicative of the quality of the separation run including computing a value indicative of the resolution of the sample peaks in the separation data, computing a value indicative of a signal-to-noise ratio in the separation data, and determining a decree of linearity of the reference peaks; andbased on the quality metric, either proceeding with a next step in analyzing the sample or repeating the separation run.