Patent ID: 9068183
Filing Date: 2015-06-30
Classification: A61K,A61P,C12N

Abstract:
1. A method of upregulating a function of and/or the expression of a Uncoupling Protein 2 (UCP2) polynucleotide in patient cells or tissues in vivo or in vitro, said patient having a UCP2 associated disease or disorder, comprising: contacting said cells or tissues with at least one antisense oligonucleotide of 12-30 nucleotides in length that specifically targets and specifically hybridizes to a region of a natural antisense oligonucleotide of the Uncoupling Protein 2 (UCP2) polynucleotide selected from SEQ ID NOS: 2 or 3; thereby upregulating a function of and/or the expression of the Uncoupling Protein 2 (UCP2) polynucleotide in patient cells or tissues in vivo or in vitro.