Patent ID: 7417045
Filing Date: 2008-08-26
Classification: A61P,C07D

Abstract:
1. A compound having the structure shown in Formula 1 or a pharmaceutically acceptable salt, wherein: Z is N, NO, or NOH; G represents a 5-membered heteroaryl or heterocyclenyl ring containing at least one —C═N— moiety as part of said heteroaryl or heterocyclenyl ring, said heteroaryl or heterocyclenyl ring optionally additionally containing on the ring one or more moieties which can be the same or different, each being independently selected from the group consisting of N, N(→O), O, S, S(O) and S(O R the R the R the R the R R ring D is a five to nine membered cycloalkyl, cycloalkenyl, aryl, heteroaryl, heterocyclenyl or heterocyclyl ring having 0-4 heteroatoms independently selected from O, S or N, wherein ring D is unsubstituted or optionally substituted with 1-5 independently selected R the R the R Y is selected from the group consisting of —(CR the R the R the R m is 0 to 4; n is 0 to 4; each q can be the same or different, each being independently selected from 1 to 5; and r is 1 to 4; with the proviso that there are no two adjacent double bonds in any ring, and that when a nitrogen is substituted by two alkyl groups, said two alkyl groups may be optionally joined to each other to form a ring.