Patent ID: 8030281
Filing Date: 2011-10-04
Classification: A61K,A61P,B01D,C07K,G01N

Abstract:
1. A method for making a particle derivative of at least one form of high density lipoprotein wherein the particle derivative comprises a protein shell and lipid comprising the steps of: a. connecting a patient to a device for withdrawing blood; b. withdrawing blood containing blood cells from the patient; c. separating the blood cells from the blood to yield a blood fraction containing high density lipoprotein and low density lipoprotein; d. separating the low density lipoprotein from the blood fraction; e. mixing the blood fraction with a solvent which removes lipid associated with the high density lipoprotein to yield a mixture of lipid, the solvent, and the particle derivative; and, f. separating the particle derivative, wherein the particle derivative comprises apolipoprotein A1 and phospholipid, from the lipid and the solvent.