Patent ID: 7994093
Filing Date: 2011-08-09
Classification: A01N,A61P,C07C,C07D

Abstract:
1. A compound of formula (I): where Het is a 5- or 6-membered heterocyclic ring containing one to three heteroatoms, each independently selected from oxygen, nitrogen and sulphur, provided that the ring is not 1,2,3-triazole, the ring being substituted by groups R 8 , R 9 and R 10 ; X is a single or double bond; Y is O, S, N(R 11 ) or (CR 12 R 13 )(CR 14 R 15 ) m (CR 16 R 17 ) n ; m is 0 or 1; n is 0 or 1; R 1 is hydrogen, C 1-4 alkyl, C 1-4 haloalkyl, C 1-4 alkoxy, C 1-4 haloalkoxy, CH 2 C≡CR 18 , CH 2 CR 19 ═CHR 20 , CH═C═CH 2 or COR 21 ; R 2 and R 3 are each, independently, hydrogen, halogen, C 1-4 alkyl, C 1-4 alkoxy or C 1-4 haloalkoxy; R 4 , R 5 , R 6 and R 7 are each, independently, hydrogen, halogen, C 1-4 alkyl, C 1-4 haloalkyl, C 1-4 alkoxy, C 1-4 haloalkoxy, C 1-4 alkylthio, C 1-4 haloalkylthio, hydroxymethyl, C 1-4 alkoxymethyl, C(O)CH 3 or C(O)OCH 3 ; R 8 , R 9 and R 10 are each, independently, hydrogen, halogen, cyano, nitro, C 1-4 alkyl, C 1-4 haloalkyl, C 1-4 alkoxy(C 1-4 )alkylene or C 1-4 haloalkoxy(C 1-4 )alkylene, provided that at least one of R 8 , R 9 and R 10 is not hydrogen; R 11 is hydrogen, C 1-4 alkyl, benzyl optionally substituted with up to three ring substituents with each ring substituent independently selected from halogen or C 1-4 alkyl or C 1-4 haloalkyl or C 1-4 alkoxy, formyl, C(O)C 1-4 alkyl optionally substituted by halogen or C 1-4 alkoxy, C(═O)O—C 1-6 alkyl optionally substituted by halogen, C 1-4 alkoxy or cyano, or C 1-4 alkoxy(C 1-4 )alkylene; R 12 , R 13 , R 14 , R 15 , R 16 and R 17 are each, independently, hydrogen, halogen, hydroxy, C 1-6 alkyl, C 2-6 alkenyl, a 3-7 membered saturated ring optionally substituted by up to three methyl groups and optionally containing one heteroatom selected from nitrogen and oxygen, or C 1-4 alkoxy, wherein each of C 1-6 alkyl and C 2-6 alkenyl may independently be optionally substituted by halogen, hydroxy, C 1-4 alkoxy, ═O, aryl or O—C(O)—C 1-4 alkyl or a 3-7 membered carboxylic ring optionally substituted by up to three methyl groups; or R 12 and R 13 together with the carbon atom to which they are attached form the group C═O or a 3-5 membered carbocyclic ring optionally substituted by up to three methyl groups and optionally with up to 2 heteroatoms each independently selected from O and N; or R 12 and R 13 together form a C 1-6 alkylidene optionally substituted by up to three methyl groups or a C 3-6 cycloalkylidene group optionally substituted by up to three methyl groups; R 18 , R 19 and R 20 are each, independently, hydrogen, halogen, C 1-4 alkyl, C 1-4 haloalkyl or C 1-4 alkoxy(C 1-4 )alkylene; and R 21 is hydrogen, C 1-6 alkyl, C 1-6 haloalkyl, C 1-4 alkoxy(C 1-4 )alkylene, C 1-4 alkyl-S—(C 1-4 )alkylene, C 1-4 alkoxy or aryl.