Patent ID: 6057092
Filing Date: 2000-05-02
Classification: G01N

Abstract:
A method to determine the location of a labeled compound as a function of time with respect to a compartmentalized biologically derived environment, which method comprisesproviding a cell, tissue or organelle marked with a scintillant in a first compartment of said cell, tissue or organelle to the exclusion of a second compartment of said biologically derived environment;positioning said scintillant-marked cell, tissue or organelle on the observation stage of a microscope focused on the marked compartment;contacting an unmarked compartment of said cell, tissue, organelle or biologically derived environment with a compound labeled with a beta-emitting radioactive isotope; andobserving the appearance of scintillant emitted light, due to proximity of the labeled compound, in the marked compartment as a function of time.