Patent ID: 7186719
Filing Date: 2007-03-06
Classification: A61P,C07D,Y02P

Abstract:
1. A compound of formula (II), or a pharmaceutically or veterinarily acceptable salt, hydrate or solvate thereof wherein Q represents a radical of formula —N(OH)CH(═O) or formula —C(O)NH(OH); when Q is —N(OH)CH(═O), R when Q is —C(═O)NH(OH), R R and A represents a group of formula (hA), or (IIB): wherein R 4 represents the characterizing group of a natural a amino acid or 4-methoxyphenylmethyl, in which any functional group may be protected, any amino group may be acylated and any carboxyl group present may be amidated; or a group -(Alk) wherein R and RB are independently a(C a benzyl group substituted in the phenyl ring by a group of formula OCH a heterocyclic(C a group —CR R the piperidinyl ring is substituted by a group of formula (IIC), provided that the piperidinyl ring is not substituted by phenoxy, benzyl or benzyl substituted by (C wherein m, p and n are independently 0 or 1; Z represents, a hydroxy group, or a phenyl or heterocyclic ring of 5 to 7 atoms which is optionally fused to a saturated or unsaturated carbocyclic or heterocyclic second ring of 5 to 7 atoms Alk X represents —O—, —S—, —S(O)—, —S(O and wherein Alk (C phenyl, or halophenyl, trifluoromethyl, monocyclic 5 or 6-membered heterocyclic, benzyl, or halophenylmethyl, hydroxy, phenoxy, (C mercapto, (C oxo, nitro, cyano (—CN) halo —COOH, or —COOR —CONH —COR —NHCOR —NH