Patent ID: 9095524
Filing Date: 2015-08-04
Classification: A61K,A61L,B33Y,B82Y,Y10S

Abstract:
1. A composition to treat age-related macular degeneration or other retinal diseases or disorders, wherein the composition comprises a three-dimensional (3D) membrane comprising electrospun nanofibers made by at least one polymer, the at least one polymer comprising PLGA, PCL, elastin, collagen or combinations thereof, wherein the membrane is ultrathin and comprises a packing density and fiber diameter sufficient to load stem cell derived retinal cells onto the membrane, the membrane further comprising a protein coat between the nanofibers and the stem cell derived retinal cells, wherein the thickness of the membrane is between about 2 microns to about 20 microns and the packing density is between about 15% to about 70% and the fiber diameter is between about 250 nm to about 670 nm.