Patent ID: 6464999
Filing Date: 2002-10-15
Classification: A61F,A61L

Abstract:
A method of forming a medical device with a bioadhesive surface comprising:copolymerizing at least a first carboxyl functional moiety-bearing monomer with at least a first hydrophobic moiety-bearing monomer to form a bioadhesive copolymer, said first hydrophobic moiety-bearing monomer being selected from the group consisting of: Z=â€”H, â€”CH3, or â€”CH2CH3 Y=nothing or O Ar=C1-C3 alkyl substituted aromatic ring or unsubstituted aromatic ring n=1-5 orR1=C1-C5 alkyl substituted aromatic ring or unsubstituted aromatic ring R2=hydrogen or C1-C5 alkyl group Z=â€”H, â€”CH3, or â€”CH2CH3 Y=nothing or O Ar=C1-C3 alkyl substituted aromatic ring or unsubstituted aromatic ring n=1-5 R1=C1-C5 alkyl substituted aromatic ring or unsubstituted aromatic ring R2=hydrogen or C1-C5 alkyl group wherein said copolymer has a tensile strength of at least about 10 psi; andproviding the bioadhesive copolymer as a surface for a medical device, such that the surface remains exposed for adhesion to a tissue.