Patent ID: 7771468
Filing Date: 2010-08-10
Classification: A61F,A61L

Abstract:
1. A stent having a coating comprising: (a) a primer layer having a polymer composition of two or more polymers, (b) a single outermost drug reservoir layer having a polymer composition comprising a mixture of two or more polymers comprising a drug stabilizing polymer, the primer layer polymer composition being distinct from the drug reservoir layer polymer composition, the drug reservoir layer further comprising one or more active agents, the drug reservoir layer protecting and stabilizing the one or more active agents during sterilization and storage, and (c) an intermediate layer between the primer layer and the drug reservoir layer, comprising a polymer composition distinct from the primer layer polymer composition and the drug reservoir layer polymer composition, the coating having sufficient adhesion and flexibility to remain intact upon stent expansion and during a sustained period thereafter, and releasing efficacious amounts of the active agent at the site of stent expansion.