Patent ID: 7718618
Filing Date: 2010-05-18
Classification: A61K,C07K,Y02A

Abstract:
1. A method for inhibiting the spread and/or reducing the risk of infection of a virus comprising contacting a virus with an inhibiting effective amount of a cathelicidin functional fragment, wherein the cathelicidin functional fragment consists of 16-20 or 26-30 amino acids in length; and contains the sequence X 1 X 2 X 3 X 4 X 5 X 6 IKX 7 FX 8 X 9 X 10 LX 11 P (SEQ ID NO:1), wherein X 1 , X 2 , and X 6 are individually K or R; wherein X 3 is I or K; wherein X 4 is V or G; wherein X 5 is Q or R; wherein X 7 , X 9 , X 10 , and X 11 are each individually any amino acid; wherein X 8 is L or F and wherein the polypeptide comprises antimicrobial and/or antiviral activity.