Patent ID: 6730252
Filing Date: 2004-05-04
Classification: A61F,A61L,B33Y,D01F

Abstract:
A method for fabricating a filament for use in tissue engineering, said method comprising:providing a polycaprolactone material; melting said polycaprolactone material at a first given temperature to form a polycaprolactone melt; holding the temperature of said polycaprolactone melt at said first given temperature for a given amount of time; lowering the temperature of said polycaprolactone melt from said first given temperature to a second given temperature after the step of holding the temperature of said polycaprolactone melt at said first given temperature for said given amount of time; extruding said polycaprolactone melt through a fiber-spinning machine, said fiber-spinning machine having spinnerets with a die exit of a given diameter, a piston set at a given speed, and a vertical drop of a given distance from said die exit to a cooling material positioned below said die exit, wherein the combination of said second given temperature, said given die exit diameter, said given piston speed, and said given distance of said vertical drop produces said filament with a given diameter for use in tissue engineering.