Patent ID: 6696085
Filing Date: 2004-02-24
Classification: A61K

Abstract:
A tablet that has disintegration properties when placed in a buccal or vaginal cavity of a subject, the tablet having a mass and comprising an active ingredient, a first disintegration agent of at least one Type C methacrylic acid copolymer according to the U.S. Pharmacopea National Formulary US/NF, and at least one second disintegration agent that is different from the first disintegration agent, with the first disintegration agent or agents being present in a total amount that provides a weight ratio of about 1:1 to about 50:1 with respect to the total amount of the second disintegration agent or agents, wherein the active ingredient and the first and second disintegration agents are incorporated into the mass of the tablet or into the mass of a sub-structure of the tablet so that the tablet has a hardness of between approximately 0.2 and 10 Kp and a friability of between approximately 0 and 25%, and the mass disintegrates in less than approximately 25 seconds when placed in the subject's buccal or vaginal cavity.