Patent ID: 7893077
Filing Date: 2011-02-22
Classification: A61P,C07D

Abstract:
1. A compound having the formula (I): or a pharmaceutically acceptable salt thereof, wherein Ar is a member selected from the group consisting of phenyl and naphthyl; each of which is optionally substituted with from one to three R 8 substituents, wherein each R 8 is a member independently selected from the group consisting of halogen, cyano, nitro, (C 1 -C 8 )alkyl, (C 1 -C 8 )alkoxy, (C 1 -C 8 )haloalkyl, (C 1 -C 8 )haloalkoxy, (C 2 -C 8 ) alkenyl, (C 2 -C 8 )alkynyl, hydroxyl and NR 12 R 13 ; B is naphthyl optionally substituted with from one to two R L is selected from the group consisting of O, S(O) each R W and Z are each N; X is C(R W is C(R R R each R each X each Q R each X each R each R optionally, R each R the subscripts k and m are independently 0 to 2.