Patent ID: 7132420
Filing Date: 2006-11-07
Classification: A61P,C07C,C07D

Abstract:
1. A compound of the formula: wherein: a, b, c, d, and e, are the same or different and are each H, R R R A is OH; B is of the formula: wherein: m, n, and z, are the same or different and each is an integer from 0 to 4; Q is SO Y is O, S, NR R L is O, S, or NH; R W of formula (If) is an organic residue comprising at least one carbon atom and sharing at least two bonds with the nitrogen atom bonded thereto such that the substituent: of formula (If) defines a heterocycle which is unsubstituted or substituted; and E is H, (CH q is an integer from 0–4; R R B and R wherein W and E are as defined above and said heterocycle is unsubstituted or substituted, B′ is of the formula B′ and R wherein W is of the formula —(CH 2 ) 2 O(CH 2 ) 2 —, and E is as defined above: wherein: when R when R when Y and/or R when R when W is substituted, one or more substituents are selected from the group consisting of oxo, thio, R when R when R when R or a pharmacologically acceptable salt thereof.