Patent ID: 6297257
Filing Date: 2001-10-02
Classification: A61P,C07D

Abstract:
A compound of formula I ##STR18##wherein A is ##STR19##whereinA is substituted by a --B--Cy group wherein B is methylene, ethylene, amino, CONH or a bond and Cy is a 5- or 6-membered heterocycle containing from 1 to 3 nitrogen atom(s) optionally substituted by one or more halogen(s), and A is optionally substituted by (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy or COOR', wherein R' is hydrogen or a (C.sub.1-4)alkyl groupR.sub.1 is a (C1-6)alkyl or polyfluoro(C1-6)alkyl group;R.sub.2 is aryl, aryl-(C1-10)-alkyl or a (C4-7)cycloalkyl group optionally containing an oxygen atom and optionally substituted by a polar substituent;and the N.fwdarw.O derivatives and pharmaceutically acceptable salts thereof.