Patent ID: 7468382
Filing Date: 2008-12-23
Classification: A61P,C07D

Abstract:
1. A compound having the following formula (I): wherein: X is a bond or C 1-6 alkyl, and wherein the C 1-6 alkyl group is optionally and independently substituted with: (A) oxo, (B) C (C) —COR (D) —OH, (E) halogen, (F) —NR Y is —NH—, —O— or —S—; R 1 is a C 3-6 cycloalkyl, aryl or heteroaryl, each of which is optionally and independently substituted with one or more of the following groups: (A) C (B) C (C) C (D) C (E) cyano, (F) halogen, (G) hydroxyl, (H) nitro, (I) —NR (J) —COR (K) —O—R R 2 is selected from the following groups: (G) —CF (H) cyano, (I) —CONH (J) halogen, or (K) nitro; R 3 is: wherein: p is an integer from 1 to 3; q is an integer from 0 to 3; n is an integer from 0 to 5; R 4 , R 5 are each independently selected from: (L) hydrogen, (M) C or a tautomer thereof, or a pharmaceutically acceptable salt thereof, or a compound of formula I where one or more amino groups are protected by an amino-protecting group.