Patent ID: 7326788
Filing Date: 2008-02-05
Classification: A61P,C07D,Y02P

Abstract:
1. A compound of Formula (I): or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof, wherein R R R X is O; and Y wherein each R 4 is independently —H, —C 1-6 alkyl, —C 2-6 alkenyl, amino, aminoalkyl, halogen, hydroxy, hydroxyalkyl, —CF 3 , alkoxy, aryl, aralkyl, heteroaryl, heteroaralkyl, aryloxy, heteroaryloxy, arylalkoxy, SR a , NR a R b , PhCF 3 , —OCF 3 , —OCO-alkyl, —COR a , —CN, —COOR a , —CONR a R b , —N(R a )COR b , —NO 2 , —SO 2 R a , —SO 3 R a or —SO 2 NR a R b , —N(R a )SO 2 R b , or wherein R a , R b , R c and R d are independently hydrogen, alkoxy, alkyl, alkenyl, cycloalkyl, aryl, aralkyl, heteroaralkyl or heteroaryl, any one of which except hydrogen may be substituted with one or more of the following: —SO 2 NH 2 , SO 2 -alkyl, or —CO 2 -alkyl.