Patent ID: 6342241
Filing Date: 2002-01-29
Classification: A61K

Abstract:
A medical composition comprising a hydroxy acid-based oligomer (A) and a drug (B), wherein the hydroxy acid-based oligomer (A) is an oligomer in which the carboxylic acid-terminals are at least partially esterified, and the oligomer (A) has a function of becoming pH 5 to 8 when administered into an organism, and the oligomer (A) shows fluidity at 25Â° C.; wherein the hydroxy acid-based oligomer (A) has a repeating unit represented by the following chemical structural formula (1) and/or a repeating unit represented by the following chemical structural formula (2) as at least a part of repeating units,â€”R in the following chemical structural formula (3) and/or â€”R in the following chemical structural formula (4) as one of at least a part of molecular terminals, and â€”OH in the following chemical structural formula (5) and/or â€”OH in the following chemical structural formula (6) as another of at least a part of molecular terminals: â€ƒwherein in the chemical structural formulae (3) and (4), R is ethyl group; and the oligomer (A) simultaneously satisfies all of the following equations (I) to (V) 0&lE;mâ€ƒâ€ƒ(I) 0&lE;nâ€ƒâ€ƒ(II) 2&lE;(n+m)&lE;30â€ƒâ€ƒ(III) 25&leq;(nn+m)Ã—100&leq;100(V)wherein m is the number of the repeating units represented by the above chemical structural formula (1), and n is the number of the repeating unit represented by the above chemical structural formula (2) in one molecule of the oligomer.