Patent ID: 8765783
Filing Date: 2014-07-01
Classification: A61K,A61P,C07D

Abstract:
1. A compound represented by formula (I): wherein: A represents wherein R (1) benzene or pyridine optionally substituted with (1) halogen, (2) alkyl, (3) halo alkyl, or (4) alkoxy; (2) C1-6 alkyl optionally substituted with (1) C1-4 alkylthio, (2) C3-7 cycloalkyl, or (3) heterocycl; (3) C3-7 cycloalkyl; and (4) naphthyl, R R r represents 0, X represents a single bond, Y represents —CO—, Z represents a nitrogen atom optionally substituted with C1-6 alkyl, B represents benzene, or pyridine, optionally with 1-5 substituent(s) selected from (1) alkyl optionally substituted with halogen atom, (2) alkenyl optionally with a substituent(s), (3) alkynyl optionally with a substituent(s), (4) carbocyclic ring optionally with a substituent(s), (5) heterocyclic ring optionally with a substituent(s), (6) hydroxyl optionally with a substituent(s), (7) thiol optionally with a substituent(s), (8) amino optionally with a substituent(s), (9) carbamoyl optionally with a substituent(s), (10) sulfamoyl optionally with a substituent(s), (11) carboxyl, (12) alkoxycarbonyl, (13) sulfo, (14) sulfino, (15) phosphono, (16) nitro, (17) cyano, (18) amidino, (19) imino, (20) —B(OH) with proviso that B represents neither 3-(2-diisopropylamino)ethoxy-4-methoxyphenyl group, 1-isopropyl-4-(2-methoxyphenyl)piperidine group, an unsubstituted benzene group, nor a benzene substituted with a halogen atom when R 1 is a benzene, or a pharmaceutically acceptable salt thereof.