Patent ID: 6465714
Filing Date: 2002-10-15
Classification: A01K,C12N

Abstract:
A congenic rat comprising genetic material of a donor Goto-Kakizaki (GK) rat and a recipient rat, said congenic animal exhibiting a type II diabetes phenotype, wherein less than one chromosome of said congenic rat's genome is derived from said donor rat, wherein said genetic material from said donor is necessary for exhibition of said type II diabetes phenotype in said congenic rat, and wherein said genetic material derived from said donor is selected from a genomic interval selected from the group consisting of NiddmC, Niddm1a, Niddm1b, Niddm1c, Niddm1d, Niddm1e, Niddm1f, Niddm1g, Niddm1h, and Niddm1i.