Patent ID: 8940903
Filing Date: 2015-01-27
Classification: A61K,A61P,C07D

Abstract:
1. A pharmaceutical composition comprising a mixture of a niacin-EPA conjugate and a niacin-DHA conjugate wherein a niacin is linked to either DHA or EPA via a linker having the formula: wherein, each a, b, c, and d is independently —H, -D, —CH m is 0, 1, 2, or 3; each n, o, p, and q is independently 0 or 1; each L is independently —O—, —S—, —S(O)—, —S(O) each e is independently H or any one of the side chains of a naturally occurring amino acid; each R is independently —H, —C(O)—C wherein Z is independently —H, or each r is independently 2, 3, or 7; each s is independently 3, 5, or 6; each t is independently 0 or 1; each v is independently 1, 2, or 6; and R