Patent ID: 7399766
Filing Date: 2008-07-15
Classification: A61P,C07D

Abstract:
1. A pyrazinoylguanidine compound represented by formula (I): wherein X is hydrogen, halogen, trifluoromethyl, lower alkyl, unsubstituted or substituted phenyl, lower alkyl-thio, phenyl-lower alkyl-thio, lower alkyl-sulfonyl, or phenyl-lower alkyl-sulfonyl; Y is hydrogen, hydroxyl, mercapto, lower alkoxy, lower alkyl-thio, halogen, lower alkyl, unsubstituted or substituted mononuclear aryl, or —N(R R each R —(CH wherein when two —CH R wherein each R wherein when two —CH wherein when two —CH each R wherein when two R wherein when two —CH each R each R each R each R each Z is, independently, CHOH, C(═O), —(CH each R each R each R with the proviso that at least one R with the additional proviso that NR each Het is independently, —NR or a pharmaceutically acceptable salt thereof, and inclusive of all enantiomers, diastereomers, and racemic mixtures thereof.