Patent ID: 8143305
Filing Date: 2012-03-27
Classification: A61P,C07D

Abstract:
1. A compound having the formula: or a pharmaceutically acceptable salt thereof, wherein: R 1 is a bond, —[C(R 12 ) 2 ] r , —[C(R 12 ) 2 ] r —O—[C(R 12 ) 2 ] q —, —[C(R 12 ) 2 ] r —N(R 9 )—[C(R 12 ) 2 ] q —, —[C(R 12 ) 2 ] q —CH═CH—[C(R 12 ) 2 ] q —, —[C(R 12 ) 2 ] q —C≡C—[C(R 12 ) 2 ] q —, or —[C(R 12 ) 2 ] q —SO 2 —[C(R 12 ) 2 ] q —; R R R each occurrence of R each occurrence of R R each occurrence of R each occurrence of R each occurrence of R each occurrence of R each occurrence of p is independently 0, 1 or 2; each occurrence of q is independently an integer ranging from 0 to 4; and each occurrence of r is independently an integer ranging from 1 to 4, wherein a 3 to 7-membered heterocycloalkyl group, a 3 to 10-membered heterocycloalkyl group, a 3 to 10-membered heterocycloalkenyl group, or a 5 to 10-membered heteroaryl group has from 1 to 4 ring heteroatoms, each independently selected from O, N and S, and any of said 3 to 7-membered heterocycloalkyl group, 3 to 10-membered heterocycloalkyl group, 3 to 10-membered heterocycloalkenyl group and 5 to 10-membered heteroaryl group can be joined to the rest of the compound via a ring carbon or ring nitrogen atom.