Patent ID: 8546607
Filing Date: 2013-10-01
Classification: C07B,C07C,C07D,C07F

Abstract:
1. A method for making a cross-coupled compound comprising: combining together: (1) an organoboron compound consisting essentially of an organoboronic acid, a diorganoborinic acid, a organoboronate ester, an organoboroxine, a organotrialkoxyborate, an organotrifluoroborate, an organotrihydroxyborate, a tetraorganoborate, a triorganoborane, an alkylborane or a tetrafluoroborate compound; (2) an aryl alcohol derivative having the structure: wherein R consists essentially of an acyl moiety; a carbamoyl moiety; a carboxyl moiety; a sulfamoyl moiety; or a phosphoryl moiety; and (3) a transition metal catalyst, wherein the transition metallic catalyst comprises nickel or palladium; wherein (1), (2) and (3) are combined so as to allow a cross-coupling reaction that results in the formation of the cross-coupled compound in a yield of at least 25%; so that the cross-coupled compound is made.