Patent ID: 9097714
Filing Date: 2015-08-04
Classification: A61P,G01N

Abstract:
1. A method of treating a malignant tumor in a subject, the method comprising: obtaining a sample from the subject having a malignant tumor, measuring a concentration, quantity, or both, of soluble LR11 in the sample with at least one substance having an affinity to soluble LR11 which is selected from the group consisting of apolipoprotein E, apo E-rich VLDL, RAP, urokinase-type plasminogen activator, PAI-1 (type-1 plasminogen activator inhibitor), uPA-PAI-1 complex and anti-soluble LR11 antibodies, comparing the concentration, quantity, or both with a soluble LR11 measurement value in a healthy subject group, and treating the malignant tumor in the subject when the concentration, quantity, or both, of soluble LR11 in the sample is higher than the soluble LR11 measurement value in the healthy subject group.