Patent ID: 8129377
Filing Date: 2012-03-06
Classification: A61P,C07D

Abstract:
1. A compound represented by the formula (I), an optically active isomer thereof, or a pharmaceutically acceptable salt thereof: wherein each symbol is as defined below. R R R a group represented by the following formula (II): wherein A represents a C R hydrogen atom, hydroxyl, a halogen, nitro, cyano a C a C a C a C a C a C a heterocycle which may be substituted, a C a C a C a C a C a C a heterocycle-oxy group which may be substituted, mercapto, a C a C a C a C a C a C a heterocycle-thio group which may be substituted, amino, a C a C a C a C a C an C a heterocycle-amino which may be substituted, a N,N-di-C a N—C a N—C a N—C a N—C a N—C a N—C a N,N-di-C a N—C a N—C a N—C a N—C a N—C a N,N-di-C a N—C a N—C a N—C a N—C a N,N-di-C a N—C a N—C a N—C a N,N-di-C a N—C a N—C a N,N-di-C a N—C a N.N-diheterocycle-amino which may be substituted, a C a C a C a C a C a C a heterocycle-carbonyl which may be substituted, a C a C a C a C a C a C a heterocycle-sulfonyl which may be substituted, carboxyl, a C a C a C a C a C a C a heterocycle-oxycarbonyl which may be substituted, aminocarbonyl, a C a C a C a C a C a C a heterocycle-aminocarbonyl which may be substituted, a N,N-di-C a N—C a N—C a N—C a N—C a N—C a N—C a N,N-di-C a N—C a N—C a N—C a N—C a N—C a N,N-di-C a N—C a N—C a N—C a N—C a N,N-di-C a N—C a N—C a N—C a N,N-di-C a N—C a N—C a N,N-di-C a N—C a N,N-di-heterocycle-aminocarbonyl which may be substituted, aminothiocarbonyl, a C a C a C a C a C a C a heterocycle-aminothiocarbonyl which may be substituted, a N,N-di-C a N—C a N—C a N—C a N—C a N—C a N—C a N,N-di-C a N—C a N—C a N—C a N—C a N—C a N,N-di-C a N—C a N—C a N—C a N—C a N,N-di-C a N—C a N—C a N—C a N,N-di-C a N—C a N—C a N,N-di-C a N—C a N,N-di-heterocycle-aminothiocarbonyl which may be substituted, r represents 0 or an integer of 1 to 5; X represents oxygen atom.