Patent ID: 8377126
Filing Date: 2013-02-19
Classification: A61L,G02B

Abstract:
1. A biomedical device including a shaped article that is a polymerization product of a monomeric mixture comprising (i) a polymerizable monomer containing a boronic acid moiety and an electron withdrawing moiety; and (ii) a biomedical device-forming comonomer; said biomedical device including, on a surface of said shaped article, a hydrophilic reactive polymer having complementary reactive functionalities along the polymer chain, wherein the complementary reactive functionalities along the polymer chain of the hydrophilic reactive polymer bind the boronic acid moieties of the shaped article, thereby producing a biocompatible coating which can be removed and re-applied to restore the surface properties of the biomedical device to, and wherein the hydrophilic reactive polymer is selected from the group consisting of a copolymer derived from 2-vinyl-4,4-dimethyl-2-oxazolin-5-one and dimethylacrylamide, and a copolymer obtained by hydrolyzing a polymerization product of a monomer mixture comprising an ethylenically unsaturated epoxy-containing monomer.