Patent ID: 8663155
Filing Date: 2014-03-04
Classification: A61K,A61M

Abstract:
1. A passive transdermal drug delivery system comprising a device for transdermally delivering a pharmacologically active agent via passive diffusion, the device comprising: a member having a plurality of stratum corneum-piercing microprotrusions, said microprotrusions having a width and thickness ranging from 5 to 50 um, and a dry coating on said member; said coating, before drying, comprising an aqueous solution of an amount of a pharmacologically active agent; wherein said pharmacologically active agent is sufficiently potent to be therapeutically effective when administered without the use of electricity in an amount less than 1 milligram, said agent having aqueous solubility at 25° C. of greater than 50 mg/ml and said aqueous solution having a viscosity at 25° C. of less than 500 centipoises, wherein said device further comprises a spring-loaded impact applicator.