Patent ID: 8399652
Filing Date: 2013-03-19
Classification: C12Q

Abstract:
1. A nucleotide array and primer mixture, together as a kit, for detecting and/or identifying the genotype of a human papilloma virus contained in a biological sample: the nucleotide array comprising a solid carrier having a surface and at least one first oligonucleotide or nucleic acid molecule bound to the carrier surface that is suitable for use as a probe for testing the HPV gene E1 or a portion thereof to detect and/or identify a genital human HPV genotype, the at least one first oligonucleotide or nucleic acid molecule selected from the group consisting of: a) HPV genotype-specific oligonucleotides having the nucleotide sequences recited in SEQ ID Nos. 8 to 135, b) oligonucleotides that have a nucleotide sequence that is mutated relative to one of the oligonucleotides of a), namely, a deletion or addition of 1 to 10 nucleotides or a substitution of 1 to 3 nucleotides in one of the nucleotide sequences recited in a), c) oligonucleotides that have a nucleotide sequence that is complementary over its entire length to the nucleotide sequence of an oligonucleotide of a) or b), d) nucleic acid molecules comprising at least one region that has one of the nucleotide sequences recited in a) to c) and one or more additional regions having a total length of at least one nucleotide, and e) mixtures of the oligonucleotides of a) to c) and/or of the nucleic acid molecules of d); and the primer mixture comprising: