Patent ID: 7727547
Filing Date: 2010-06-01
Classification: A61L

Abstract:
1. A tissue-adhesive formulation comprising a naturally occurring or synthetic polymerisable and/or cross-linkable material in particulate form, the polymerisable and/or cross-linkable material is in admixture with particulate material comprising tissue-reactive functional groups, wherein the polymerisable and/or cross-linkable material is albumin, and wherein the particulate material comprising tissue-reactive functional groups is the reaction product of poly(N-vinyl-2-pyrrolidone-co-acrylic acid) co-polymer and a reactant comprising a tissue-reactive functional group wherein the tissue-reactive functional group is selected from the group consisting of imido ester, p-nitrophenyl carbonate, N-hydroxysuccinimide ester, epoxide, isocyanate, acrylate, vinyl sulfone, orthopyridyl-disulfide, maleimide, aldehyde and iodoacetamide.