Patent ID: 9107948
Filing Date: 2015-08-18
Classification: A61K,A61P,B82Y

Abstract:
1. A compound and the pharmaceutically acceptable salts thereof, of the formula (I) Signal-Peptide or (II) Signal-Linker-Peptide, wherein: Signal is a signal entity; Linker is a chemical linking component; and Peptide is a peptide consisting of a mucin 5A (MUC5AC)-targeting peptide, X1 is absent or cysteine or methionine, X2 is hydroxyproline or proline, X3 is threonine or serine, X4 is isoleucine, leucine or valine, X5 is tyrosine, phenylalanine or tryptophan, X6 is hydroxyproline or proline, X7 is isoleucine, leucine or valine X8 is isoleucine, leucine or valine X9 is absent or cysteine or methionine; X10 is absent or cysteine or methionine, X11 is isoleucine, leucine, valine or alanine, X12 is threonine or serine, X13 is isoleucine, leucine or valine, X14 is hydroxyproline or proline, X15 is hydroxyproline or proline, X16 is isoleucine, leucine or valine, X17 is isoleucine, leucine or valine, X18 is absent or cysteine or methionine; and