Patent ID: 9034369
Filing Date: 2015-05-19
Classification: A61K,A61L,A61P,G01N

Abstract:
1. A method for manufacturing a vaginal article, the method comprising the steps of: a. forming a tampon pledget comprising rayon, wherein the rayon fibers include a calcium salt that was added thereto prior to formation of the tampon pledget; and b. compressing and/or shaping the tampon pledget into a finished tampon configuration that is different than that of the tampon pledget, wherein the calcium salt comprises calcium lactate and/or calcium citrate malate, wherein the calcium salt is included in an amount sufficient to reduce the production of TSST-1 by at least 50% when measured by the Shake Flask Method described herein, and wherein the calcium salt is substantially non-lethal to Lactobacillus crispatus, Lactobacillus gasseri, and Lactobacillus iners when measured by the Maximum Tolerated Dose Test described herein.