Patent ID: 6106829
Filing Date: 2000-08-22
Classification: A61K,C12N

Abstract:
An isolated polypeptide comprising a polypeptide selected from the group consisting of:(a) a polypeptide consisting of amino acids 1 to 316 of SEQ ID NO:2;(b) a polypeptide consisting of amino acids 2 to 316 of SEQ ID NO:2;(c) a polypeptide encoded by a polynucleotide which hybridizes with the complement of the coding portion of the polynucleotide of SEQ ID NO:1, wherein said polypeptide binds an antibody specific for the polypeptide of (a), wherein said antibody is produced by direct injection of the polypeptide of (a) into an animal, and wherein said hybridization takes place under hybridization conditions comprising hybridization in a buffer consisting of 0.5M NaPO.sub.4, pH 7.4 and 7% SDS at 65.degree. C. and wash in a buffer consisting of 0.5.times.SSC 0.1% SDS at 60.degree. C.; and(d) a fragment of the polypeptide of (a) which binds an antibody specific for the polypeptide of (a) and wherein said antibody is produced by direct injection of the polypeptide of (a) into an animal.