Patent ID: 9180122
Filing Date: 2015-11-10
Classification: A61K,A61P,C07D

Abstract:
1. A compound of formula (I), or a pharmaceutically acceptable salt thereof: wherein R A represents a group —X—Y—R B represents R R m is 0, 1 or 2; R 4 represents a C 1 -C 6 alkyl group; R 5 and R 6 independently are each chosen from a hydrogen atom or a C 1 -C 6 alkyl group; X and Y independently are each chosen from a bond, an oxygen atom, or a group —C(O), —S(O) n , —C(O)NR 7 , —S(O) 2 NR 7 , —NR 7 , or —CR 7 R 8 —, with the proviso that X and Y cannot both simultaneously represent a bond and, if X and Y are both not a bond, then at least one of X and Y represents —CR 7 R 8 —, n is 0, 1 or 2; each R 7 independently is chosen from a hydrogen atom or a C 1 -C 6 alkyl group; each R 8 independently is chosen from a hydrogen atom, a C 1 -C 6 alkyl group or ═CH—; R 3 is chosen from a 3- to 10-membered saturated or unsaturated carbocyclic or heterocyclic ring system, wherein the ring system is unsubstituted or substituted by at least one substituent chosen from halogen, hydroxyl, cyano, oxo, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 1 -C 6 haloalkyl, C 1 -C 6 hydroxyalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 alkylsulphinyl, C 1 -C 6 alkylsulphonyl, C 1 -C 6 alkylcarbonyl, C 1 -C 6 alkylcarbonyloxy, C 1 -C 6 alkoxycarbonyl, amino (—NH 2 ), —CON(R 9 ) 2 , C 1 -C 6 alkylamino, di-(C 1 -C 6 alkyl)amino, C 3 -C 6 cycloalkyl, C 3 -C 6 cycloalkyloxy, C 3 -C 6 cycloalkylmethyl, —[O] p —(CH 2 ) q —O—R 10 , or a 4- to 6-membered saturated or unsaturated heterocyclic ring that is unsubstituted or substituted with at least one substituent chosen from C 1 -C 4 alkyl or C 1 -C 4 alkoxy; each R 9 independently is chosen from a hydrogen atom or a C 1 -C 6 alkyl group; p is 0 or 1; q is 1, 2, 3 or 4; and R 10 represents a C1-C6 alkyl group.