Patent ID: 8071093
Filing Date: 2011-12-06
Classification: A61P,C07K

Abstract:
1. An isolated human monoclonal antibody or a binding fragment thereof that binds human epidermal growth factor receptor (EGFR) wherein the antibody comprising a heavy chain variable domain comprising a heavy chain complementarity determining region (H-CDR) 1 (H-CDR1) sequence of SEQ ID NO: 1; an H-CDR2 sequence of SEQ ID NO: 2; and an H-CDR3 sequence of SEQ ID NO: 3; and a light chain variable domain comprising a light chain complementarity determining region (L-CDR) 1 (L-CDR1) sequence of SEQ ID NO: 4; an L-CDR2 sequence of SEQ ID NO: 5; and an L-CDR3 sequence of SEQ ID NO: 6; or a binding fragment thereof, wherein the fragment binds human EGFR.