Patent ID: 8148430
Filing Date: 2012-04-03
Classification: C07C,C07D

Abstract:
1. A process for the hydrogenation of a compound, comprising hydrogenating a C 6 -C 18 aromatic substituted amino acid or C 6 -C 18 aromatic substituted amino alcohol in the presence of a platinum-rhodium mixed catalyst, wherein said C 6 -C 18 aromatic substituted amino acid or C 6 -C 18 aromatic substituted amino alcohol is of formula (I): wherein n is 0, 1 or 2; R R R P P the carbon atom marked with * is an asymmetrical carbon atom; and wherein; said process produces a yield of greater than 94% after a reaction time of about 6 to 8 hours; and the hydrogenation reaction is performed in the presence of a solvent consisting of a mixture of water and an alcohol.