Patent ID: 7858844
Filing Date: 2010-12-28
Classification: A01K,C07K,C12N,C12P,Y10S

Abstract:
1. A non-human transgenic organism comprising a transgene, wherein said transgene comprises a nucleic acid that encodes a non-aggregating chromo- or fluorescent mutant of an aggregating Cnidarian chromo- or fluorescent protein wherein said non-aggregating chromo- or fluorescent mutant has a sequence identity to 85% or more with a protein encoded by a full length nucleotide sequence selected from the group consisting of SEQ ID NOs: 13, 14, 15, 17, 19, 21, and 23 and has a negatively charged or neutral residue at one or more residues corresponding to a basic residue located within about 25 residues of the N-terminus of a corresponding wild type sequence.