Patent ID: 8431143
Filing Date: 2013-04-30
Classification: A61K,A61P,B82Y

Abstract:
1. A method of treating a lesion, comprising the steps of administering a dispersion to an animal including human wherein the dispersion comprises a titanium dioxide composite dispersed in an aqueous solvent where the titanium dioxide composite comprises a titanium dioxide particle, a hydrophilic polymer bonded to the surface of the titanium dioxide particle and a pharmaceutical compound bonded to the hydrophilic polymer, wherein the pharmaceutical compound is doxorubicin, the lesion is a cancer tissue and the amount of the doxorubicin is 0.5 to 5 mg per gram of the titanium dioxide particles wherein the titanium dioxide particle has a particle diameter of 2 to 200 nm, and subsequently irradiating with UV light a region other than the lesion at least surrounding the lesion, without irradiating the lesion, to photoexcite titanium dioxide in the titanium dioxide composite contained in the dispersion, so that the pharmaceutical compound is decomposed by photoexcitation of the titanium dioxide to allow the drug efficacy to disappear.