Patent ID: 6204264
Filing Date: 2001-03-20
Classification: A61K,A61Q,C07D

Abstract:
A benzimidazole compound or a salt thereof expressed by the following Formula (I): ##STR74##wherein each of A and B is R.sup.1 or --(CH.sub.2).sub.n --NR.sup.2 R.sup.3, wherein when A is R.sup.1, B is --(CH.sub.2).sub.n --NR.sup.2 R.sup.3 and when A is --(CH.sub.2).sub.n --NR.sup.2 R.sup.3, B is R.sup.1 ;R.sup.1 is a hydrocarbon group having 10 to 30 carbon atoms;R.sup.2 and R.sup.3 individually represent a hydrogen atom, a lower alkyl group, a phenyl group or a benzyl group, or --NR.sup.2 R.sup.3 may be a heterocycle having 3-7 members; wherein when B is --(CH.sub.2).sub.n --NR.sup.2 R.sup.3 and m=1, --(CONR.sup.5).sub.m --B may be the following Group (W): ##STR75##wherein R.sup.2 is a hydrogen atom, a lower alkyl group, a phenyl group or a benzyl group and ring E is a heterocycle of 6 or 7 members;R.sup.4 is selected from the group consisting of a hydrogen atom, a halogen atom, a cyano group, a trifluoromethyl group, a lower alkyl group, a lower acyl group, a carboxyl group, a lower alkoxycarbonyl group, a carbamoyl group, a lower alkylcarbamoyl group, an amino group, a lower alkylamino group, a lower acylamino group, a hydroxy group, a lower alkoxy group and a lower acyloxy group;R.sup.5 is a hydrogen atom, a lower alkyl group, a lower acyl group or a lower alkylcarbamoyl group; wherein when B is --(CH.sub.2).sub.n --NR.sup.2 R.sup.3 and m=1, --(CONR.sup.5).sub.m --B may be Group (W);m is 0 or 1;n is an integer of 0-5; andwherein when m is 0 then A is --(CH.sub.2).sub.n --NR.sup.2 R.sup.3 and B is an alkyl group having at least 10 carbon atoms.