Patent ID: 8535258
Filing Date: 2013-09-17
Classification: A61M

Abstract:
1. A method for treating a patient experiencing Inflammatory Mediator Related Diseases, the method comprising: providing a network of medical tubing; fluidly coupling the network of medical tubing to the patient for removal of blood and delivery of fluids; fluidly coupling a hemofilter to the network of medical tubing, wherein the hemofilter has a molecular weight exclusion limit equal to or greater than approximately 69,000 Daltons and is operable to remove an ultrafiltrate from the blood stream in a portion of the network of medical tubing and to create a filtered blood stream for return to the patient through a portion of the network of medical tubing and an ultrafiltrate stream; fluidly coupling a waste reservoir to the network of medical tubing; fluidly coupling an adsorptive device to a portion of the network of medical tubing, wherein the adsorptive device contains at least one adsorbent material operable to receive the ultrafiltrate stream from the hemofilter and to remove an inflammatory mediator therefrom to create a post adsorption ultrafiltrate routable to at least one of the patient or to the waste reservoir; administering a therapeutic agent to the patient for treating Inflammatory Mediator Related disease; and wherein the step of administering a therapeutic agent includes administering at least one of the following agents: statin drugs, T-cell function augmenting drugs, non-steroidal anti-inflammatory drugs, resolvins, N-acetylcysteine, pentoxifylline, antioxidants, Inducible nitric oxide synthase (iNOS) inhibitors, calcium activated potassium channel inhibitors, histone deacetylase inhibitors, peroxynitrite inhibitors, proteasome inhibitors, dimemorfan, activators for antioxidant response elements, stabilizers of antioxidant elements, and antioxidant inflammation modulators.