Patent ID: 6797724
Filing Date: 2004-09-28
Classification: A01N,A61K

Abstract:
A composition for the treatment or protection of a domestic animal against parasitic infestation by topical application to a localized region and diffusion therefrom over the animal's body, the composition comprising, in the form of a ready-to-use solution:(a) an insecticidal active substance of the formula (X): (b) an organic solvent selected from the group consisting of acetyl tributyl citrate, fatty acid esters, diisobutyl adipate, acetone, acetonitrile, benzyl alcohol, butyl diglycol, dimethylacetamide, dimethylformamide, dipropylene glycol n-butyl ether, ethanol, isopropanol, methanol, ethylene glycol monoethyl ether, ethylene glycol monomethyl ether, monomethylacetamide, dipropylene glycol monomethyl ether, liquid polyoxyethylene glycols, propylene glycol, 2-pyrrolidone, N-methylpyrrolidone, diethylene glycol monoethyl ether, ethylene glycol, and diethyl phthalate, or a mixture of at least two of these solvents; and (c) a vehicle selected from the group consisting of soybean oil, groundnut oil, castor oil, corn oil, cotton oil, olive oil, grape seed oil, sunflower oil, petroleum, paraffin, silicone, aliphatic or cyclic hydrocarbons, and medium-chain (C8 to C12 in particular) triglycerides; and (d) an emollient selected from the group consisting of polyvinylpyrrolidone, polyvinyl alcohols, copolymers of vinyl acetate, and vinylpyrrolidone, polyethylene glycols, benzyl alcohol, mannitol, glycerol, sorbitol, polyoxyethylenated sorbitan esters, lecithin, sodium carboxymethylcellulose, silicone oils, anionic surfactants, cationic surfactants, nonionic surfactants, and amphoteric surfactants, or a mixture of at least two of these agents; wherein the composition comprises from 0.05 to 25% weight/volume of the compound of formula (X), and the compound of formula (X) is applied in a dose between 0.1 and 2 mg/kg animal weight.