Patent ID: 7750000
Filing Date: 2010-07-06
Classification: A61P,C07D

Abstract:
1. A compound selected from the group consisting of: (3-phenylimidazo[1,2b]pyridazin-6-yl)-(3-pyrrolidin-1-ylpropyl)amine (3-morpholin-4-ylpropyl)-(3-phenylimidazo[1,2b]pyridazin-6-yl)amine (3-(3-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl)-(3-pyrrolidin-1-ylpropyl)amine (3-(3-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl)-(3-morpholin-4-ylpropyl)amine [3-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2b]pyridazin-6-yl]pyridin-3-ylmethylamine (3-phenylimidazo[1,2b]pyridazin-6-yl)pyridin-3-ylmethylamine (3-imidazol-1-ylpropyl)-(3-phenylimidazo[1,2b]pyridazin-6-yl)amine (4-fluorobenzyl)-(3-phenylimidazo[1,2b]pyridazin-6-yl)amine cyclohexylmethyl-(3-phenylimidazo[1,2-b]pyridazin-6-yl)amine (2,4-difluorobenzyl)-(3-phenylimidazo[1,2b]pyridazin-6-yl)amine [3-(5-methyl-1H-pyrazol-4-yl)propyl]-(3-phenylimidazo[1,2-b]pyridazin-6-yl)amine 1-[2-(3-phenylimidazo[1,2-b]pyridazin-6-ylamino)ethyl]imidazolidin-2-one (2-morpholin-4-ylethyl))-(3-phenylimidazo[1,2-b]pyridazin-6-yl)amine N N,N-diethyl-N′-(3-phenylimidazo[1,2-b]pyridazin-6-yl)propane-1,3-diamine (3-phenylimidazo[1,2-b]pyridazin-6-yl)-(2-pyrrolidin-1-ylethyl)amine [3-(3-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl]pyridin-3ylmethylamine [3-(3-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl]-(3-imidazol-1-ylpropyl)amine 3-(3-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl)-(4-fluorobenzyl)amine 3-(3-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl)cyclohexylmethylamine 3-(3-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl)-(2,4-difluorobenzyl)amine 1-{2-[3-(3-phenyl)imidazo[1,2-b]pyridazin-6-ylamino]ethyl}imidazolidin-2-one N N′-[3-(3-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl]-N,N-diethylpropane-1,3-diamine [3-(3-chlorophenyl)imidazo[1,2b]pyridazin-6-yl]-(2-pyrrolidin-1-ylethyl)amine (3-imidazol-1-ylpropyl)-[3-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-6-yl]amine (4-fluorobenzyl)-[3-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-6-yl]amine cyclohexylmethyl-[3-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-6-yl]amine (2,4-difluorobenzyl)-[3-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-6-yl]amine [3-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2b]pyridazin-6-yl]-[5-methyl-1H-pyrazol-4-yl)propyl]amine 1-{2-[3-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-6-ylamino]ethyl}imidazolidin-2-one (3-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-6-yl)-(2-morpholin-4-ylethyl)amine N N,N-diethyl-N′-[3-(1-methyl-1H-1-pyrazol-4-yl)imidazo[1,2-b]pyridazin-6-yl]propane-1,3-diamine [3-(1-methyl-1H-pyrazol-4-yl)imidazo [1,2-b]pyridazin-6-yl-(2-pyrrolidin-1-ylethyl)amine pyridin-3-ylmethyl-(3-thiophen-3-ylimidazo[1,2-b]pyridazin-6-yl)amine (4-fluorobenzyl)-(3-thiophen-3-ylimidazo[1,2-b]pyridazin-6-yl)amine cyclohexylmethyl-(3-thiophen-3-ylimidazo[1,2-b]pyridazin-6-yl)amine (2,4-difluorobenzyl)-(3-thiophen-3-ylimidazo[1,2-b]pyridazin-6-yl)amine [3-(5-methyl-1H-pyrazol-4-yl)propyl)-(3-thiophen-3-ylimidazo[1,2-b]pyridazin-6-yl)amine 1-[2-(3-thiophen-3-ylimidazo[1,2-b]pyridazin-6-ylamino)ethyl]imidazolidin-2-one (2-morpholin-4-ylethyl)-(3-thiophen-3-ylimidazO[1,2-b]pyridazin-6-yl)amine N N,N-diethyl-N′-(3-thiophen-3-ylimidazo[1,2-b]pyridazin-6-yl]propane-1,3-diamine and (2-pyrrolidin-1-ylethyl)-(3-thiophen-3-ylimidazo[1,2-b]pyridazin-6-yl)amine.