Patent ID: 8633027
Filing Date: 2014-01-21
Classification: A61F,A61K,A61L,A61P,C07K,C12N,Y10T

Abstract:
1. A method of making a knitted, biodegradable, silk fabric comprised of a yarn having sericin-extracted silk fibroin fibers that retain their native protein structure and have not been dissolved and reconstituted, the method comprising: before or after forming the yarn or fabric extracting sericin from non-randomly organized silk fibroin fibers in a Na 2 CO 3 and soap solution at a temperature at or below 94° C., the sericin-extracted silk fibroin fibers being biocompatible and biodegradable such that the yarn promotes ingrowth of cells around the silk fibroin fibers, wherein cells for proliferating and differentiating into a tissue have not been added to or absorbed into the fabric.