Patent ID: 6472541
Filing Date: 2002-10-29
Classification: C07F,C07H,Y02P

Abstract:
A compound of formula wherein:A is â€”OH, â€”OC(O)CH3, NH2, or â€”NHCH3; each of X1 and X2, independently, is H, Cl, Br, or I, with at least one of X1 and X2 being Cl, Br, or I; Q is â€”Oâ€”,â€”NHâ€”, or â€”NCH3â€”; Y1 is â€”H, â€”Cl, â€”Br, â€”I, â€”C(O)OH, â€”NO2, â€”C(O)NHR1, â€”CN, â€”C(O)H, â€”C(O)CH3, benzoxazol-2-yl, benzothiazol-2-yl, or benzimidazol-2-yl; Y2 is â€”H, â€”C(O)OH, or â€”SO3H; M1 is â€”H, â€”CH3, â€”NR2R3, â€”C(O)NR2R3, or â€”COOH; Z is â€”Cl, â€”Br, â€”Iâ€”, â€”OH, â€”OC(O)R4, â€”OP(O)R5R6 and M2 is â€”H; or Z and M2 together are &boxH;N2, &boxH;O, or &boxH;NNHR1; each of R1, R2, and R3, independently, is a substituted or unsubstituted moiety selected from the group consisting of a C1-20 alkyl, a C2-20 alkenyl, a C2-20 alkynyl, a C1-20 alkoxy, a C1-20 thioalkoxy, a C1-20 alkylsulfonyl, a C4-16 arylsulfonyl, a C2-20 heteroalkyl, a C2-20 heteroalkenyl, a C3-8 cycloalkyl, a C3-8 cycloalkenyl, a C4-16 aryl, a C4-16 heteroaryl, and a C2-30 heterocyclyl; and each of R4, R5, and R6 independently, is a substituted or unsubstituted moiety selected from the group consisting of a C1-20 alkyl, a C2-20 alkenyl, a C4-16 aryl, a C2-20 heteroalkyl, an amino acid radical, a peptide radical, a polynucleotide radical, and a nucleoside radical or R5 and R6 together can form a nucleoside diradical; or a salt thereof.