Patent ID: 7718576
Filing Date: 2010-05-18
Classification: C07D,C12Q

Abstract:
1. A method for detecting the presence of a peroxide compound or a free radical thereof comprising contacting an aqueous or mixed aqueous-organic solution of said peroxide compound or free radical thereof with a chemiluminescent agent and detecting the chemiluminesence generated by reaction of the chemiluminescent agent with the peroxide compound or free radical thereof to be detected, wherein said chemiluminescent agent comprises a chemiluminescent compound defined by the formula: where C* is an sp A is defined by the formula wherein R Z is O; and Q is a suitable leaving group which yields a compound capable of exhibiting a chemiluminescent reaction in the presence of a peroxide or peroxide-like compound under aqueous or mixed aqueous-organic conditions, wherein the leaving group Q is an N-linked optionally substituted heterocyclic aryl moiety selected from the group consisting of imidazole, oxazole, thiazole, pyrazole, pyrimidine, purine, quinoline, isoquinoline, pyrrole, indole, pyridine, tetrazole, triazole, and carbazole, and detecting the chemiluminescence generated by reaction of said compound with said peroxide compound or free radical thereof to be detected.