Patent ID: 6051225
Filing Date: 2000-04-18
Classification: A61K,A61P,C07K

Abstract:
An antibody produced by one of the cell lines CH44-1 (ATCC HB9884), CH44-2 (ATCC HB9880), CH44-4 (ATCC HB9877), CH88-1 (ATCC HB9882), CH88-2 (ATCC HB9881), CH88-3 (ATCC HB9876), CH88-4 (ATCC HB9874), CH84-1 (ATCC HB9883), CH84-2 (ATCC HB9879), CH84-3 (ATCC HB9878), or CH84-4 (ATCC HB9875), or an antigen binding fragment thereof, wherein said antibody is capable of binding to TAG-72 with an affinity at least 25% greater than that of B72.3, with the binding affinities of B72.3 and said antibody being measured by the same technique.