Patent ID: 9034593
Filing Date: 2015-05-19
Classification: A61B,A61F,C12Q,G01N

Abstract:
1. A diagnostic kit for biomarkers of beneficial vaginal health comprising: a sample pad; a lateral chromatographic medium, the lateral chromatographic medium defining a first detection zone within which a D-lactic acid detection signal is capable of being generated, the D-lactic acid detection signal comprising a color change generated from a non-diffusively immobilized chromogen that is contained within the first detection zone, the D-lactic acid detection signal being generated in response to an enzyme-catalyzed reaction of D-lactic acid present in a sample, wherein the quantity of D-lactic acid present in the sample is determinable from the D-lactic acid detection signal, the chromatographic medium further defining a second detection zone within which a hydrogen peroxide detection signal is capable of being generated, the hydrogen peroxide detection signal comprising a color change generated from a non-diffusively immoblized chromogen that is contained within the second detection zone, wherein the presence or quantity of vaginal hydrogen peroxide present in a sample is determinable from the hydrogen peroxide detection signal, the lateral chromatographic medium providing for lateral flow from the sample pad through the first detection zone and through the second detection zone; and an absorbent material downstream of the lateral chromatograhic medium.