Patent ID: 7700271
Filing Date: 2010-04-20
Classification: A61P,C07K,G01N

Abstract:
1. A method for detecting an aberrant mammary epithelial cell in a subject or in a biological sample from said subject, said method comprising contacting cells or cell extracts from said subject or said biological sample with an antibody specific for LIM domain only 4 (LMO4), screening for the level of antibody-LMO4 complex formation, comparing the level of the LMO4-antibody complex in the cells from said subject or said sample with the level of the LMO4-antibody complex in normal cells, and determining the presence of an aberrant mammary epithelial cell based on an elevated level of the LMO4-antibody complex in the cells from said subject or said sample relative to normal mammary epithelial cells.