Patent ID: 6417225
Filing Date: 2002-07-09
Classification: A61K,A61P,C07D

Abstract:
A method for treating or preventing artherosclerosis comprising administering to a patient in need thereof an effective amount of a compound of the formula: wherein R1 represents a hydrogen atom, an acyl group or an arylalkoxycarbonyl group; R2 represents a lower alkyl group; R3 represents a hydrogen atom or a lower alkyl group; and R4, R5, and R6 may be identical or different and each represents a hydrogen atom, an optionally substituted alkyl group, an optionally substituted alkenyl group, or an optionally substituted alkynyl group, or R2 and R4 together with the oxygen atom may form a furan or dihydrofuran ring, or R5 and R6 may combine to form a cycloalkyl group or a heterosubstituted cycloalkyl group in which one or more methylene groups of the cycloalkyl group are replaced by oxygen, sulfur, or alkyl-substituted nitrogen atoms, provided that R6 is absent when R2 and R4 together with the oxygen form a furan ring, an optically active isomer, or a pharmaceutically acceptable salt thereof.