Patent ID: 6156793
Filing Date: 2000-12-05
Classification: A61K,A61P,C07D

Abstract:
A method for prevention or treatment of xanthomatosis in a patient in need thereof which comprises administering to the patient a prophylactically or therapeutically effective amount of a compound of general formula (1): ##STR3## wherein R.sup.1 represents a hydrogen atom, an acyl group or an arylalkoxycarbonyl group,R.sup.2 represents a lower alkyl group,R.sup.3 represents a hydrogen atom or a lower alkyl group, andR.sup.4, R.sup.5 and R.sup.6 may be identical or different and each represent a hydrogen atom, an optionally substituted alkyl group, an optionally substituted alkenyl group, an optionally substituted alkynyl group, an optionally substituted aryl group or an optionally substituted arylalkyl group, orR.sup.2 and R.sup.4 together with the oxygen atom may form a furan or dihydrofuran ring, orR.sup.5 and R.sup.6 may combine to form a cycloalkyl group or a heterosubstituted cycloalkyl group in which one or more methylene groups of the cycloalkyl group are replaced by oxygen, sulfur or alkyl-substituted nitrogen atoms, provided that R.sup.6 is absent when R.sup.2 and R.sup.4 together with the oxygen atom form a furan ring, a possible optically active isomer or a pharmaceutically acceptable salt thereof.