Patent ID: 8273863
Filing Date: 2012-09-25
Classification: C12N,C12Q,Y10T

Abstract:
1. A nucleic acid ladder consisting essentially of a plurality of double stranded nucleic acid fragments, each fragment having a size in base pairs of between 20 kb and 100 base pairs, a copy number, a mass, and a relative mass wherein the mass of each fragment is the size in base pairs of the fragment multiplied by the copy number of the fragment, wherein the relative mass of each fragment is the mass of the fragment divided by the sum of the masses of all of the fragments, wherein the relative mass of any one fragment of the plurality is no more than 3 time the relative mass of any other fragment of the plurality, wherein at least two of the plurality of nucleic acid fragments have a size greater than 1 kb, and wherein at least two of the plurality of nucleic acid fragments have a size less than 1 kb, wherein the nucleic acid ladder lacks a highlight fragment.