Patent ID: 9096858
Filing Date: 2015-08-04
Classification: A61K,A61P,C12N,Y02A

Abstract:
1. A method for therapeutically treating a mammal having cancer where inhibiting a TLR7- and/or TLR9-mediated immune response would be beneficial, such method comprising administering to the mammal an antagonist of TLR7 and/or TLR9 having the structure 5′—N p N 3 N 2 N 1 C*G1N 1 N 2 N 3 N z N 4 N 5 -3′ (SEQ ID NO: 72), wherein C*G* is an oligonucleotide motif wherein C* is 5-Me-dC, and G1 is 7-deaza-dG; N N N N N p is 5; and z is 3;