Patent ID: 8110568
Filing Date: 2012-02-07
Classification: A61K,A61P,C07D,C07K,C12N

Abstract:
1. A method of inducing apoptosis in a cell comprising introducing into said cell a compound a therapeutically effective amount of a compound of formula I: wherein X Y is (CHR A is a 5-member heterocycle comprising 1 to 4 heteroatoms optionally substituted with amino, hydroxyl, mercapto, halogen, carboxyl, amidino, guanidino, alkyl, alkoxy, aryl, aryloxy, acyl, acyloxy, acylamino, alkoxycarbonylamino, cycloalkyl, alkylthio, alkylsulfinyl, alkylsulfonyl, aminosulfonyl, alkylaminosulfonyl, alkylsulfonylamino or a heterocycle; wherein each alkyl, alkoxy, aryl, aryloxy, acyl, acyloxy, acylamino, cycloalkyl and heterocycle substitution is optionally substituted with hydroxyl, halogen, mercapto, carboxyl, alkyl, alkoxy, haloalkyl, amino, nitro, cyano, cycloalkyl, aryl or a heterocycle; R R R R R R and a pharmaceutically acceptable salt thereof.