Patent ID: 6878363
Filing Date: 2005-04-12
Classification: A61K

Abstract:
1. A method for diagnosing a neurological disease involving APP processing and/or beta-amyloid production within a mammalian body comprising: (a) administering a diagnostically effective amount of a radiopharmaceutical secretase inhibitor of APP processing and/or beta-amyloid production; its tritiated formula, (I-7T), its tritiated formula (I-11T), its tritiated formula (I-43T) Tritiated (2S,3R) N1-[1,3-dihydro-1-methyl-2-oxo-5-(phenyl)-2H-1,4-benzodiazepin-3-yl]-2-(2-methylpropyl)-3-(n-propyl)-butanediamide, (b) imaging the area of the patient wherein, the disease is located.