Patent ID: 6436425
Filing Date: 2002-08-20
Classification: A61K,A61L,A61P

Abstract:
A method of inhibiting the formation/reformation of internal adhesions which comprises administering to the tissues of a mammal an aqueous non-gelling composition comprising:about 65%-95% by weight of water, about 5% to 35% by weight of a polyoxyalkylene block polymer of the formula: â€ƒY[(A)nâ€”Eâ€”H]x wherein A is a polyoxyalkylene moiety having an oxygen/carbon atom ratio of less than approximately 0.5, x is at least 1, Y is derived from water or an organic compound containing x reactive hydrogen atoms, E is a polyoxyethylene moiety, n has a value such that such that the minimum molecular weight of A is between about 500 to about 900, as determined by the hydroxyl number of an intermediate of the formula:Y[(A)â€”H]x and the total molecular weight of the polyoxyalkylene block copolymer is at least about 5000.