Patent ID: 7824691
Filing Date: 2010-11-02
Classification: A61K,A61P,C07K,Y02A

Abstract:
1. A method of treating or reducing the risk of bacterial infection in a mammalian individual, comprising administering to said individual a composition comprising an amount of an isolated RNAIII-inhibiting peptide (RIP) and an antimicrobial peptide capable of binding and neutralizing a lipidic and polyanionic component of a bacterial cell envelope, where the RIP and antimicrobial peptide are present in an amount effective to treat or reduce the risk of a bacterial infection in said individual, where the bacterial infection is caused by Staphylococcus spp Bacillus spp., B. subtilus, B. cereus, B. anthracis, Listeria spp., L. innocua, L. monocytogenes, Streptococcus pyogenes, Lactococcus lactis, Enterococcus faecalis, Escherichia coli , or Clostridium acetobtylicum.