Patent ID: 6866993
Filing Date: 2005-03-15
Classification: C12Q,G01N

Abstract:
1. A method for determining whether a test compound is a candidate modulator of the drug resistance of a cell, the method comprising: a) determining the level of expression of a gene encoding a protein comprising the amino acid sequence of SEQ ID NO:2 in a cell in the presence of a test compound; b) determining the level of expression of the gene encoding a protein comprising the amino acid sequence of SEQ ID NO:2 in the cell in the absence of the test compound; and c) identifying the compound as a candidate modulator of drug resistance in the cell if the level of expression of the gene encoding a protein comprising the amino acid sequence of SEQ ID NO:2 in the cell in the presence of the test compound differs from the level of expression of the gene encoding a protein comprising the amino acid sequence of SEQ ID NO:2 in the cell in the absence of the test compound.