Patent ID: 6797717
Filing Date: 2004-09-28
Classification: A61P,C07D

Abstract:
A compound represented by the following formula IV, a salt thereof or a solvated product thereof: X represents â€”NHâ€”, oxygen atom or sulfur atom; Y represents â€”NR4â€”, oxygen atom, sulfur atom, sulfoxide or sulfone; Z represents single bond; R1, R2 and R3 may be the same or different and represent hydrogen atom, a lower alkyl group, a lower alkoxyl group, halogen atom, hydroxyl group, phosphate group, sulfonamide group, or amino group which may or may not have a substituent; otherwise, any combination of two of R1, R2 and R3 represents an alkylene dioxy group; R4 represents hydrogen atom, a lower alkyl group, an aryl group or a silylated lower alkyl group which may or may not have a substituent; and R9, R10, R9â€², R10â€², R9â€³R10â€³, R9â€²â€³, and R10â€²â€³, may be the same or different and represent hydrogen atom, a lower alkyl group which may or may not have a substituent, a lower alkoxyl group which may or may not have a substituent, halogen atom, hydroxyl group, carboxyl group, an alkoxycarbonyl group which may or may not have a substituent, an alkylcarbonyloxy group which may or may not have a substituent, an alkylcarbonyl group which may or may not have a substituent, carbamoyl group which may or may not have a substituent, a hydroxyalkyl group, phosphate group, sulfonamide group, amino group which may or may not have a substituent, an aminoalkyl group which may or may not have a substituent, or a heterocyclic residue; otherwise, any combination of two thereof represents an alkylene dioxy group; and n represents an integer of 2 to 15; with the proviso that when X is sulfur atom then