Patent ID: 6281003
Filing Date: 2001-08-28
Classification: C12P

Abstract:
Method of preparing optically active hydroxamic acids of the formula ##STR9##wherein R.sup.1, R.sup.2 and R.sup.3 are different and are a cyclic or linear, aliphatic or aromatic, substituted or unsubstituted hydrocarbon radical which optionally contain heteroatoms, comprising reacting a racemate of chiral amides, carboxylic acid esters or carboxylic acids of the formula ##STR10##wherein R.sup.1, R.sup.2 and R.sup.3 are as defined above and X is --NH.sub.2, --OR or --OH, R being any organic radical,with hydroxylamine, NH.sub.2 OH, in the presence of an acyltransferase, and then separating the optically active hydroxamic acid (I) formed from the unconverted enantiomer of general formula (II).