Patent ID: 8188416
Filing Date: 2012-05-29
Classification: A61B,B33Y

Abstract:
1. A method for improving image-based characterization of perfusion in microvascular networks, comprising the steps of: (a) perfusing a phantom comprising an artificial microvascular network of known structure and dimensions with a fluid; (b) selecting a perfusion parameter and determining, based on the known structure and dimensions of the network, a first value of the selected perfusion parameter; (c) inducing contrast in a portion of the fluid present in the artificial microvascular network; (d) acquiring a series of images of the phantom in accordance with an imaging scheme; (e) computing from the series of images a second value for the selected perfusion parameter based on an analysis scheme; and (f) varying at least one of the imaging scheme or the analysis scheme based on a comparison of the first and second values.