Patent ID: 6369047
Filing Date: 2002-04-09
Classification: A61P,C07J

Abstract:
An androgenic steroid compound of the formula (II) wherein:R1 is H; R2 is an &agr;-substituent which is unsubstituted lower alkyl or fluoro-substituted lower alkyl; R3 is H, or an acyl group (CO)â€”R4, where R4 is C1-18 alkyl, alkenyl or alkynyl, or R4 is C4-18 cycloalkyl or substituted cycloalkyl, or R4 is C6-18 aryl or substituted aryl or R4 is a 5 to 15 membered heterocycle or substituted heterocycle, and wherein R4 may optionally be substituted with 1 to 3 heteroatoms or 1 to 5 halogen atoms; R5is &agr;-H; and R6 is &bgr;-unsubstituted or substituted lower alkyl, unsubstituted or substituted alkenyl or unsubstituted or substituted alkynyl, or R5 and R6 is &boxH;CH2; and X is O, (H,OH) or (H,OCOR4) where R4 is as defined above.