Patent ID: 6987187
Filing Date: 2006-01-17
Classification: C07D

Abstract:
1. A process for producing a compound of the formula (II): wherein ring A represents a 5 to 9 membered alicyclic group, which may contain at least one of O, S, SO, SO R R is optionally substituted aryl or optionally substituted aromatic heterocyclic group; and Hal is a halogen, comprising Step 1, wherein a compound of the formula (v): wherein R is reacted with a halogenating agent in acetonitrile in the presence of dimethylformamide and then hydrolyzed to obtain a compound of the formula (IV): wherein ring A is as defined above, and Hal is a halogen, Step 2, wherein the resultant compound (IV) is reacted with a compound of the formula R—COR wherein ring A, Hal and R are as defined above, and Step 3, wherein the obtained compound of the formula (III) is reacted with a halogenating agent in acetonitrile in the presence of an organic base and then aminated.