Patent ID: 9119883
Filing Date: 2015-09-01
Classification: A61K,A61P,C07D

Abstract:
1. A method for reduction of food intake and for treatment of obesity and diseases, conditions or disorders which can be alleviated by reduction of food intake, including hypertension, dyslipidemia, cardiovascular risk, insulin-resistance, and diabetes mellitus, said method comprising administering to an individual in need an effective amount of a conjugate of the formula: wherein Y is a PYY agonist; and X is a radical of the formula (i): wherein R R R R A is OCO— linked to an amino group of the PYY agonist; and n is an integer of at least one, provided that: (i) when R Z is O, S or NH that is linked to the PEG moiety; and R (ii) when R and Z is O, S or NH; (iii) when R (iv) when R (v) when R (vi) when R