Patent ID: 7504203
Filing Date: 2009-03-17
Classification: C12N,C12Q,G01N

Abstract:
1. A method for assessing sensitivity of a rice blast fungus to a scytalone dehydratase inhibitor comprising the steps of: (a) identifying an amino acid in the amino acid sequence of a scytalone dehydratase isolated from the rice blast fungus, wherein said amino acid corresponds to valine at position 75 of SEQ ID NO: 4; and (b) assessing sensitivity of the rice blast fungus to the scytalone dehydratase inhibitor, wherein if the amino acid identified in step (a) is methionine, the sensitivity of the rice blast fungus to the scytalone dehydratase inhibitor is assessed to be lower than that of the wild-type rice blast fungus which endogenously produces the scytalone dehydratase of SEQ ID NO: 4.