Patent ID: 8642634
Filing Date: 2014-02-04
Classification: A01N,A61P,C07D

Abstract:
1. A compound selected from Formula 1, an N-oxide and salt thereof, wherein R A is CHR R R W is O or S; X is a radical selected from wherein the bond of X each R two R two R G is an optionally substituted 5-membered heteroaromatic ring or 5-membered saturated or partially saturated heterocyclic ring; J is a 5-, 6- or 7-membered ring, a 8- to 11-membered bicyclic ring system or a 7- to 11-membered spirocyclic ring system, each ring or ring system containing ring members selected from carbon and optionally 1 to 4 heteroatoms selected from up to 2 O, up to 2 S and up to 4 N, and optionally including 1 to 3 ring members selected from the group consisting of C(═O), C(═S), S(O), S(O) each R each R each R each R each Q is independently phenyl, benzyl, naphthalenyl, a 5- or 6-membered heteroaromatic ring or an 8- to 11-membered heteroaromatic bicyclic ring system, each optionally substituted with 1 to 5 substituents independently selected from R each Q is independently a 3- to 7-membered nonaromatic carbocyclic ring, a 5-, 6- or 7-membered nonaromatic heterocyclic ring or an 8- to 11-membered nonaromatic bicyclic ring system, each optionally including ring members selected from the group consisting of C(═O), C(═S), S(O), S(O) each R R each R each Z each Z each R each R each m is independently 0, 1 or 2; and n is 0, 1 or 2; provided that: (a) when R (b) when A is NR (c) when A is CHR then when J is a substituted phenyl or substituted pyrimidin-4-yl, it is substituted with at least one R