Patent ID: 6333361
Filing Date: 2001-12-25
Classification: A61K,A61P

Abstract:
A pharmaceutical composition comprising4-(5-cyclopentyloxycarbonylamino-1-methylindol-3-ylmethyl)-3-methoxy-N-o-to lylsulfonylbenzamide or a pharmaceutically acceptable salt thereof, and, as gelling agent, hydroxypropylmethylcellulose, wherein the hydroxypropylmethylcellulose is selected from the group consisting of:a) a hydroxypropylmethylcellulose having a viscosity of about 40 to 60 cps, a methoxy content of about 20 to 30% by weight and a hydroxypropoxy content of from about 7 to less than 9% by weight;b) a hydroxypropylmethylcellulose having a viscosity of about 3,500 to 5,600 cps, a methoxy content of about 28 to 30% by weight and a hydroxypropoxy content of about 7 to 12% by weight;c) a hydroxypropylmethlylcellulose having a viscosity of about 80 to 120 cps, a methoxy content of about 19 to 24% by weight and a hydroxypropoxy content of from about 7 to less than 9% by weight; andd) a hydroxypropylmethylcellulose having a viscosity of about 5,500 to 5,600 cps, a methoxy content of about 19 to 24% by weight and a hydroxypropoxy content of about 7 to 12% by weight, or mixtures thereof.