Patent ID: 8808696
Filing Date: 2014-08-19
Classification: A61K,A61P,C07K

Abstract:
1. A method of treating a multiple myeloma, comprising administering to a human patient with multiple myeloma who has become resistant to or who has failed to respond to at least one other method of treatment of the multiple myeloma a composition comprising a fusion molecule selected from the group consisting of: (a) a fusion molecule comprising (b) a fusion molecule comprising amino acids 30-110 of SEQ ID NO: 1 and a human immunoglobulin-constant domain; (c) a fusion molecule consisting of amino acids 30-110 of SEQ ID NO: 1 and a human immunoglobulin-constant domain; (d) a fusion molecule consisting of SEQ ID NO: 2; and (e) a fusion molecule consisting of amino acids 30-110 of SEQ ID NO:1 and the human immunoglobulin-constant domain of SEQ ID NO: 2; wherein said composition is administered in an amount from 2.0 mg per 1 kg of patient's body weight to 10 mg per 1 kg of patient's body weight and wherein said composition is administered weekly.