Patent ID: 7671074
Filing Date: 2010-03-02
Classification: A61P,C07C,C07D

Abstract:
1. A sulfonylguanidine compound selected from the group consisting of: N-{amino-[pyridin-2-yl-methyl)-amino]-methylene}-4-methylbenzenesulfonamide (1) N-[amino-(benzylaminomethylene)]-4-methylbenzene-sulfonamide (2) N-[(amino-4-methoxybenzylamino)-methylene]-4-methylbenzene-sulfonamide (6) N-[aminophenethylaminomethylene]-4-methylbeuzene-sulfonamide (14) N-{amino-[(pyridin-2-yl-methyl)-amino]-methylene}-4-chlorobenzenesulfonamide (21) N-{amino-[(pyridin-4-yl-methyl)-amino]-methylene}-4-methylbenzenesulfonamide (22) N-{amino-[(pyridin-3-yl-methyl)-amino]-methylene}-4-ethylbenzenesulfonamide (23) N-{amino[(pyridin-2-yl-methyl)-amino]-methylene}-4-bromobenzenesulfonamide (32) N-{amino[(pyridin-2-yl-methyl)-amino]-methylene}-3,4-dichlorobenzenesulfonamide (33) N-{amino[(pyridin-2-yl-methyl)-amino]-methylene}-4-isopropylbenzenesulfonamide (34) N-{amino[(pyridin-2-yl-methyl)-amino]-methylene}-4-iodobenzenesulfonamide (35) N-{amino[(pyridin-2-yl-methyl)-amino]-methylene}-benzenesulfonamide (36) Naphthalene-2-sulfonic acid amino-[(pyridin-2-yl-methyl)-amino]-methylene amide (37) 1-methyl-1H-imidazole-4-sulfonic acid amino-[(pyridin-2-yl-methyl)-amino]-methylene amide (38) N-[4-({amino-[(pyridin-2-yl-methyl)-amino]-methylene}-sulfamoyl)-phenyl]-acetamide (39) N-{amino[(pyridin-2-yl-methyl)-amino]-methylene}-4-fluorobenzenesulfonamide (40) N-{amino[(pyridin-2-yl-methyl)-amino]-methylene}-2,4,6-trimethylbenzenesulfonamide (41) N-{amino[(pyridin-2-yl-methyl)-amino]-methylene}-4-propylbenzenesulfonamide (42) N-{amino[(pyridin-2-yl-methyl)-amino]-methylene}-4-methoxybenzenesulfonamide (43) Naphthalene-1-sulfonic acid amino-[(pyridin-2-yl-methyl)-amino]-methylene amide (44) N-{amino[(pyridin-2-yl-methyl)-amino]-methylene}-3-methylbenzenesulfonamide (45) Thiophene-2-sulfonic acid amino-[(pyridin-2-yl-methyl)-amino]-methylene amide (46) Quinoline -8-sulfonic acid amino-[(pyridin-2-yl-methyl)-amino]-methylene amide (47) 5-chloro-3-methylbenzo[b]thiophene-2-sulfonic acid amino-[(pyridin-2-yl-methyl)-amino]-methylene amide (48) N-{amino[(pyridin-2-yl-methyl)-amino]-methylene}-4-tert.-butylbenzenesulfonamide (49) N-{amino[(pyridin-2-yl-methyl)-amino]-methylene}-4-butylbenzenesulfonamide (50) N-{amino[(pyrimidin-2-yl-methyl)-amino]-methylene}-4-tert.-butylbenzenesulfonamide (51) N-{amino[(furan-2-yl-methyl)-amino]-methylene}-4-butylbenzenesulfonamide (52) N-{amino[(furan-2-yl-methyl)-amino]-methylene}-4-methylbenzenesulfonamide (53) N-{amino[(furan-2-yl-methyl)-amino]-methylene}-4-isopropylbenzenesulfonamide (54) N-{amino[(furan-2-yl-methyl)-amino]-methylene}-4-propylbenzenesulfonamide (55) N-{amino[(furan-2-yl-methyl)-amino]-methylene}-4-tert.-butylbenzenesulfonamide (56) N-{amino[(thiophen-2-yl-methyl)-amino]-methylene}-4-butylbenzenesulfonamide (57) N-{amino[(thiophen-2-yl-methyl)-amino]-methylene}-4-propylbenzenesulfonamide (58) N-{amino[(thiophen-2-yl-methyl)-amino]-methylene}-4-isopropylbenzenesulfonamide (59) N-{amino[(thiophen-2-yl-methyl)-amino]-methylene}-4-tert.-butylbenzenesulfonamide (60) N-{amino[(thiophen-2-yl-methyl)-amino]-methylene}-4-chlorobenzenesulfonamide (61) N-{amino[(thiophen-2-yl-methyl)-amino]-methylene}-4-methylbenzenesulfonamide (62), and N-{amino[(furan-2-yl-methyl)-amino]-methylene}-4-chlorobenzenesulfonamide (63), optionally in the form of a racemate, a pure enantiomer or diastereomer, or in the form of mixtures of the stereoisomers in an equimolar or nonequimolar mixing ratio; in the represented form or in the form of an acid or a base; or in the form of a physiologically compatible salt.