Patent ID: 6528651
Filing Date: 2003-03-04
Classification: C07D

Abstract:
A process for the preparation of a compound of the Formula (I) whereinR1 is hydrogen or alkyl, R2 is hydrogen, alkyl, cycloalkyl or â€”CH2R3, R3 is alkenyl, alkinyl, or aryl or heteroaryl each of which is optionally substituted, Het is an unsubstituted or substituted aromatic or non-aromatic, monocyclic or bicyclic heterocyclic radical, comprising the step of: reacting a compound of the formula (II) â€ƒwherein R1, R2 and Het are as defined above, and R4 is alkyl, cycloalkyl, aryl, arylalkyl or heterocyclylalkyl, each of which may be unsubstituted or substituted, with anhydrous hydrogen chloride or with one or more compounds which can generate hydrogen chloride in the presence or absence of a diluent.