Patent ID: 6211366
Filing Date: 2001-04-03
Classification: A61P,C07D

Abstract:
A compound of the formula: ##STR25##or a pharmaceutically acceptable salt thereof, wherein:A represents --CH.dbd.CH--, or A represents --X--CH.sub.2 --; where X is CH.sub.2 or oxygen, provided that when X is oxygen, the oxygen is adjacent the 6-membered ring;R.sub.1, R.sub.2, R.sub.3, and R.sub.4 are the same or different and represent hydrogen, halogen, hydroxy, amino, aminosulfonyl, alkylaminosufonyl, arylalkylsulfonyl, alkylsulfonyl, alkyl of 1 to 6 carbon atoms or alkoxy of 1 to 6 carbon atoms; andR.sub.5 represents alkyl having 1-3 carbon atoms and R.sub.6 is benzyl, unsubstituted or substituted with alkyl having 1-6 carbon atoms, alkoxy, hydroxy, or halogen; orNR.sub.5 R.sub.6 represents a heterocyclic six membered ring unsubstituted or substituted with alkyl having 1-6 carbon atoms, hydroxyl, halogen, aryl, alkylaryl where the alkyl portion is alkyl having 1-6 carbon atoms, or heteroaryl.