Patent ID: 8686189
Filing Date: 2014-04-01
Classification: C07B,C07C,C07D

Abstract:
1. A process for producing an acid adduct salt of a compound represented by formula (VI-I): wherein R 1 represents a C2-C5 alkoxycarbonyl group and R 3 represents a dimethylcarbamoyl group, said process comprising: treating a compound represented by formula (A) with an azide in the presence or absence of a phase-transfer catalyst to obtain a mixture comprising a compound represented by formula (V-I) and a compound represented by formula (B): subjecting said mixture to hydrogenolysis in a C1-C4 alcoholic solvent in the presence of a metallic catalyst and a hydrogen source to obtain a mixture comprising the compound represented by formula (VI-I) and a compound represented by formula (C): wherein R followed by adding oxalic acid, to obtain an acid adduct salt of the compound represented by formula (VI-I).