Patent ID: 7091230
Filing Date: 2006-08-15
Classification: A61P,C07C,C07D

Abstract:
1. A compound having the formula I: including pharmaceutically acceptable salts thereof, wherein R R R R R Each R Each R Aryl is an aromatic carbocyclic mono- or bicyclic ring system containing 6–10 atoms in the ring or rings; Heteroaryl is a mono- or bicyclic aromatic ring system containing 4–11 atoms in the ring or rings, wherein at least one atom in the ring or rings is a heteroatom selected from N, O and S; Heterocycle is a fully or partially saturated monocyclic or bicyclic ring system having 4–11 atoms in the ring or rings and at least one heteroatom selected from O, N, and S in the ring or rings; Alicyclic is a substituent group that has one C Ar X is O or S; and Z is selected from the group consisting of —COOH, tetrazole, and —C(O)NHS(O)