Patent ID: 7482468
Filing Date: 2009-01-27
Classification: A61P,C07D

Abstract:
1. A compound represented by the structural formula or a pharmaceutically acceptable salt thereof, wherein: n is 2, 3, 4 or 5; R is a 5- or 6-membered heteroaryl or heterocycloalkyl group, wherein one ring atom of the R group is nitrogen and the remaining ring atoms are carbon, and wherein the R group is optionally substituted with R R X is —O—, —S— or —NR Z is p is 1-3; q is 1-4 and r is 1-4, provided that the sum of q and r is 3-6; s is 1; R R R each R R R R R R each R a heteroaryl group is defined as a 2- to 14-membered carbocyclic group having from 1 to 4 of it's ring carbon atoms independently replaced with an oxygen, nitrogen or sulfur atom such that the heteroaryl group does not have adjacent oxygen and/or sulfur ring atoms, and wherein all available carbon and nitrogen ring atoms can be substituted as defined above; and a heterocycloalkyl group is defined as a 3- to 15 -membered carbocyclic group having from 1 to 3 of it's ring carbon atoms independently replaced with —O—, —S—, —S(O)—, —S(O)