Patent ID: 9161963
Filing Date: 2015-10-20
Classification: A61K,A61P

Abstract:
1. A liquid pharmaceutical composition comprising: (a) a ciclosporin in an amount of up to 5 mg/ml; (b) an aqueous carrier liquid; (c) a first solubility enhancing substance selected from the group of phospholipids; and (d) a second solubility enhancing substance selected from the group of nonionic surfactants, wherein (i) the phospholipid is a lecithin, (ii) the weight ratio of the phospholipid to the nonionic surfactant is between 14:1 and 12:1, (iii) the weight ratio of the phospholipid and the nonionic surfactant to the ciclosporin is between 8:1 and 12:1, and (iv) the composition contains the ciclosporin in liposomally solubilised form.