Patent ID: 7749980
Filing Date: 2010-07-06
Classification: A61K,A61P

Abstract:
1. A method of treating pain comprising administering to a subject in need thereof an effective amount of a compound of Formula III, a tautomer, or a pharmaceutically-acceptable salt, hydrate, or solvate thereof: wherein R a and R b are each independently selected from the group consisting of: hydrogen, saturated or unsaturated C 1-8 alkyl, saturated or unsaturated C 3-7 cycloalkyl, aralkyl, aryl, and saturated or unsaturated C 2-6 heterocycle; or R R Σ=L, R each R two R one R R is selected from the group consisting of: H, saturated or unsaturated C L is selected from the group consisting of: H, —CF when L is N-substituted-amino, or N,N-disubstituted-amino, each substituent of said amino group of L is selected from the group consisting of: C when L is N,N-disubstituted-amino, the two substituents independently selected from the group above are optionally taken together to form a ring of 3 to 7 members, wherein said formed ring thereon bears the remaining features of said selected substituents before said ring formation; R R when R J=N or C, with the proviso that when J=N, then R when J=C, R when R X M is independently selected from the group consisting of: —H, halogen, CF