Patent ID: 9181530
Filing Date: 2015-11-10
Classification: A61K,A61P,C07K,C12N,C12Q

Abstract:
1. An infectious hepatitis E virus (HEV) type 3 cDNA clone, wherein the infectious clone comprises an insert, relative to the HEV nucleic acid sequence set forth in SEQ ID NO:5, in the region of the nucleic acid sequence that encodes the hypervariable region of ORF1, wherein the insert encodes an in-frame polypeptide sequence of 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, or 65 amino acids in length that has at least 85% identity to SEQ ID NO:9 over its length when maximally aligned to SEQ ID NO:9.