Patent ID: 6111068
Filing Date: 2000-08-29
Classification: A61K,A61P,C07K,C12N,Y10S

Abstract:
A peptide having from about 30 to about 50 consecutive amino acids taken from the following sequence:SEQ ID NO:1) 1 5 10 Xaa Ser Leu Xaa Asn Thr Val Xaa Xaa Leu Xaa Xaa Val - 15 20 25 His Xaa Xaa Ile Xaa Xaa Xaa Asp Thr Lys Glu Ala Leu - 30 35 Asp Xaa Xaa Xaa Glu Glu Gln Asn Lys Xaa Gln Gln Lys - 40 45 50 Xaa Xaa Thr Xaa Xaa Xaa Xaa Xaa Ala Asp Xaa Gly Xaa - 55 Val Ser Gln whereinXaa position 1 is Arg, Lys or Ile;Xaa position 4 is Tyr, Phe or His;Xaa position 8 is Ala or Val;Xaa position 9 is Thr or Val;Xaa position 11 is Tyr or Trp;Xaa position 12 is Cys or Ser;Xaa position 15 is Lys, Glu, or Ala;Xaa position 16 is Gly, Lys, Asp, Glu, or Arg;Xaa position 18 is Glu or Thr;Xaa position 19 is Val or Ile;Xaa position 20 is Arg or Gln;Xaa position 28 is Lys, Arg or Glu;Xaa position 29 is Ile or Leu;Xaa position 30 is Glu or Lys;Xaa position 36 is Ile, Ser or Cys;Xaa position 40 is Thr or is a direct bond;Xaa position 41 is Lys or is a direct bond;Xaa position 43 is Gln or is a direct bond;Xaa position 44 is Gln, Lys or is a direct bond;Xaa position 45 is Ala or Glu;Xaa position 46 is Lys, Glu or Ala;Xaa position 47 is Thr, Ala or Glu;Xaa position 50 is Lys, Asn, or a direct bond; and,Xaa position 52 is Lys or Gln.