Patent ID: 6479656
Filing Date: 2002-11-12
Classification: B01J,C07F,C07H

Abstract:
A process for phosphorylation of a hydroxyfunctional compound having one or more hydroxyl group substituents by phosphitylation followed by oxidation comprising addition of a phosphitylation reagent or phosphorous compound to a hydroxyfunctional compound having at least one hydroxyl group which addition yields a product having at least one Oâ€”P bond wherein said phosphorylation is performed in the presence of at least one catalyst of general formula (R1)nX(R2)4âˆ’n whereini) each R1 independently is a) at least one alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, cycloaliknyl, aryl, alkylaryl, alkenylaryl, alkynylaryl, trityl, alkoxy, cycloalkoxy, or aryloxy, b) a polymeric moiety selected from the group consisting of organic polymer, copolymer and analogues thereof, c) at least one halogenated and/or silylated alkanyl, alkenyl, alkyl, cycloalkanyl, cycloalkenyl, cycloalkynyl, aryl, alkanylaryl, alkenylaryl, alkynylaryl, trityl, alkoxy, cycloalkoxy, aryloxy or amino group, or d) a polymeric moiety derived from a compound selected from the group consisting of a halogenated organic polymer, a halogenated organic copolymer, a silylated organic polymer, a silylated organic copolymer, a mixture of silylated and halogenated organic polymers, a mixture of silylated and halogenated organic copolymers, and analogues thereof; ii) X is Si; iii) each R2 independently is a leaving group and is a) F, Cl, Br or I; or b) a sulphonate group of formula â€ƒwherein R3 is F, Cl, Br, I, alkyl, alkenyl, alkynyl, aryl, arylalkanyl, arylalkenyl, arylalkynyl, haloalkanyl, haloalkenyl, haloalkynyl, haloaryl, haloarylalkanyl, haloarylalkenyl, haloarylalkynyl, arylhaloalkanyl, arylhaloalkenyl, arylhaloalkynyl or a group of formula R4 wherein R4 is selected from the group consisting of CF3, CCl3, CBr3 and CI3, and iv) n is 1, 2 or 3.