Patent ID: 6503918
Filing Date: 2003-01-07
Classification: A61K,A61P,C07B,C07C,Y10S

Abstract:
A solid composition comprising a pharmacologically active component and D-Mannitol, said D-Mannitol (a) being in the &bgr; form crystals alone or a mixture of the &bgr; form crystals with the &dgr; form crystals, (b) having a specific surface area of not less than about 1 m2/g and (c) being produced by a process which comprises moistening the surface of &dgr; form D-Mannitol crystals with a water-soluble solvent without dissolving the &dgr; form D-Mannitol crystals completely in the water-soluble solvent, followed by drying the moistened &dgr; form D-Mannitol crystals to obtain the D-Mannitol.