Patent ID: 8889635
Filing Date: 2014-11-18
Classification: A61K,A61P

Abstract:
1. A composition comprising pain relief complexes and pain relief antagonist complexes; wherein said pain relief complexes consist of dendrimers separately conjugated with 1) a pain relief agent via an ester linkage agent, wherein said pain relief agent is morphine, 2) a locking agent, wherein said locking agent is trigonelline, and 3) a targeting agent, wherein said targeting agent is transferrin; wherein said pain relief antagonist complexes consist of dendrimers separately conjugated with 1) a pain relief agent antagonist via an indolequinone trigger agent, wherein said pain relief agent antagonist is naloxone, 2) a locking agent, wherein said locking agent is trigonelline, and 3) a targeting agent, wherein said targeting agent is transferrin; wherein said pain relief antagonist complexes are configured to prevent respiratory depression caused said pain relief complexes; wherein said dendrimers within said pain relief complexes and pain relief antagonist complexes are separate within said composition.