Patent ID: 8431698
Filing Date: 2013-04-30
Classification: C07D,G01N

Abstract:
1. A method of using a bioluminescence system to illuminate internal body structures of a subject comprising: administering to the subject or one or more portions thereof at least one coelenterazine analog selected from the group consisting of Structure II, Structure II wherein R4 and R5 may independently be alkyl or aralkyl, and R4 may be aryl or optionally substituted aryl, aralkyl or optionally substituted aralkyl, and R5 may be alkyl, optionally substituted alkyl, alkoxy, aralkyl, or optionally substituted aralkyl, aryl, or a heterocycle, Structure III, Structure III wherein p may be an integer ranging from 1 to 20, and Structure IV, Structure IV wherein R1, R2, and R3 are independently alkyl, optionally substituted alkyl, alkenyl, or aralkyl; and visualizing and/or imaging said subject or one or more portions thereof.