Patent ID: 8431340
Filing Date: 2013-04-30
Classification: B01F,B01J,B01L,C12Q,G01N

Abstract:
1. A method for processing and analyzing a nucleic acid sample comprising the steps of: a) concentrating a nucleic acid analyte in a macroscale module by: b) introducing, with pressure from a pressure source, the released magnetic beads with the captured nucleic acid analyte in the reduced volume into a bioprocessor module that is fluidically integrated with the macroscale module, wherein introducing comprises passing the magnetic beads with the captured nucleic acid analyte from the macroscale module through a microfluidic channel in a microfluidic chip and into a reaction chamber in the bioprocessor module wherein the microfluidic channel is in fluidic communication with the macroscale module and with the reaction chamber; c) amplifying the nucleic acid analyte in the reaction chamber; and d) analyzing the amplified nucleic acid analyte in an analysis module fluidically integrated with the bioprocessor module.