Patent ID: 6641838
Filing Date: 2003-11-04
Classification: A61K,Y10S

Abstract:
A dosage form for delivery of a therapeutically effective amount of a drug to a target area in the gastrointestinal tract of a mammal, said dosage form comprising:(a) a therapeutically effective amount of a drug; (b) at least one effervescent penetration enhancer present in an amount sufficient to increase the penetration of said drug across said target area of said gastrointestinal tract to permit delivery of said therapeutically effective amount of said drug, wherein said amount of said at least one effervescent penetration enhancer is at least about two times the amount of said drug; and (c) an enteric coating maintained over said drug and said at least one effervescent penetration enhancer; wherein said enteric coating prevents the release of said drug and said at least one effervescent penetration enhancer until a time at which said dosage form reaches said target area in said gastrointestinal tract.