Patent ID: 7227022
Filing Date: 2007-06-05
Classification: A61P,C07D

Abstract:
1. A process for the preparation of a compound of the formula (II) in which either Y is a methylene and X is selected from O, NH, N-(C1–C4)alkyl, N-Bn, N-Ph, N-(2-Py), N-(3-Py), N-(4-Py), N-2-pyrimidyl, N-5-pyrimidyl, S, SO, SO or Y is a carboxyl and X is selected from: NH, N-Ph, N-(2-Py), N-(3-Py), N-(4-Py), N-2-pyrimidyl and N-5-pyrimidyl; said (C1–C4)alkyl consisting of 1 to 4 carbons in a straight or branched chain, and said abbreviations Bn, Py and Ph signifying, respectively, benzyl, pyridyl and phenyl, said process comprising reacting a compound of formula (IIa):