Patent ID: 6239286
Filing Date: 2001-05-29
Classification: C07C,C07D

Abstract:
A process for the preparation of compounds of general formula (I): ##STR1##wherein R means hydrogen atom or C.sub.2-6 alkyl group characterized in thata) the compound of general formula (III): ##STR2##is reacted with a compound of general formula (IV): ##STR3##wherein the meaning of R is defined above, and X means halogen atom or C.sub.1-5 alkoxy group or hydroxyl group, and the resulting compound of general formula (II): ##STR4##wherein the meaning of R is defined above, is transformed in the presence of an oxidizing agent in a reaction medium with pH above 7, into the compound of general formula (I), wherein the meaning of R is as defined above, orb) the compound of formula (III) is reacted with an anhydride of general formula (V): ##STR5##wherein the meaning of R is the same as defined above, and the resulting compound of general formula (II), wherein the meaning of R is as given above, is transformed in the presence of an oxidizing agent, in a reaction medium with pH above 7, into the compound of general formula (I), orc) a compound of general formula (II), wherein the meaning of R is the same as defined above, is transformed in the presence of an oxidizing agent, in a reaction medium with pH above 7, into the compound of general formula (I), and optionally, the resulting compounds of general formula (I), before or after isolation, are transformed into acid addition salts, or the compounds of general formula (I) are liberated from their acid addition salts, characterized in that the reaction is carried out in homogeneous phase.