Patent ID: 6596753
Filing Date: 2003-07-22
Classification: A61K,A61P,A61Q,C07D

Abstract:
A method for the treatment of disorders associated with overactivity of type II 5&agr;-reductase comprising administering to a patient in need of such treatment an effective amount of at least one compound corresponding to the formula (I) in which Y represents a hydrogen atom or a radical â€”OCHR3R4, in which R3 is a hydrogen atom or an optionally substituted phenyl radical or alternatively a 5- or 6-membered heterocycle and R4 is an optionally substituted phenyl radical or alternatively a 5- or 6-membered heterocycle, or R3 and R4 taken together form, with the carbon atom, a 5- or 6-membered ring or heterocycle; X represents a hydrogen atom; Z represents a hydrogen atom or a radical â€”OR5 in which R5 is a C1-C6 alkyl radical or a C6-C12 aralkyl radical; R1 represents a hydrogen atom or a C1-C6 alkyl radical or a C6-C12 aralkyl radical which is optionally substituted; R2 represents a hydrogen atom or a C1-C6 alkyl radical or a radical â€”CHR3R4, in which R3 and R4 have the above definitions.