Patent ID: 7125865
Filing Date: 2006-10-24
Classification: C07D

Abstract:
1. A compound of formula I or a pharmaceutically acceptable salt, ester or tautomer thereof, wherein R R R Y is joined together with the nitrogen and the carbonyl carbon shown in Formula I to which Y is respectively attached, to form a heterocyclic ring selected from: provided that when R wherein each carbon atom in the heterocyclic ring, formed when Y is joined together with the nitrogen and the carbonyl carbon shown in Formula I, is independently unsubstituted, mono- or di-substituted with a substituent independently selected at each occurrence from R R R Z is selected from the group consisting of: and wherein the pharmaceutically acceptable ester of the compound of formula I is selected from the group consisting of (a) a phenyl ester, (b) a —C 1-6 alkyl ester and (c) a substituted C 1-4 alkyl ester wherein the substituent is selected from the group consisting of phenyl-, dimethylamino- and acetylamino-.