Patent ID: 6187587
Filing Date: 2001-02-13
Classification: A61K,A61P,C07H,C12N,Y02P

Abstract:
An antisense compound up to 30 nucleobases in length targeted to a nucleic acid molecule encoding E2F transcription factor 1, wherein said antisense compound specifically hybridizes with and inhibits the expression of E2F transcription factor 1 and wherein said antisense compound has a sequence comprising at least an 8 nucleobase portion of SEQ ID NO: 14, 19, 22, 23, 24, 25, 26, 30, 31, 33, 34, 36, 38, 39, 40, 41, 42, 44, 45, 49, 50, 51, 52, 54, 56, 57, 58, 60, 61, 62, 63, 64, 66, 67, 68, 69, 73, 74, 75, 77, 79, 81, 83, 84, 85, 86, 87, or 88.