Patent ID: 6828336
Filing Date: 2004-12-07
Classification: A61K,A61P

Abstract:
A nicotine containing composition in powder form comprising about 10 to about 499 mg per gram of an organic polyol, about 2 to about 980 mg per grain of a cation exchange resin selected from the group consisting of (i)â€”a methacrylic, weakly acidic type of resin containing carboxylic functional groups (ii)â€”polystyrene, strongly acidic type of resin containing sulfonic functional groups and (iii)â€”polystyrene, intermediate acidic type of resin containing phosphoric functional groups, said cation exchange resin having some of its ion exchange sites partially blocked with said polyol and about 10 to about 499 mg per gram of nicotine produced by the process comprising the steps of (a) preparing an aqueous solution of the organic polyol (b) mixing said aqueous solution of the organic polyol with said cation exchange resin thereby forming a mixture of a cation exchange resin having some of its ion exchange sites partially blocked with said polyol (c) admixing with said mixture of step (b) an aqueous solution of nicotine to form a nicotine-coated cation exchange resin admixture and (d) removing water from said admixture to produce said nicotine-containing composition in powder form having a nicotine release rate of not less than 70% over a ten minute period.