Patent ID: 7429608
Filing Date: 2008-09-30
Classification: A61P,C07D

Abstract:
1. A compound having the structure: or any pharmaceutically-acceptable salt thereof, wherein: J is NH; n is independently, at each instance, 0, 1 or 2; R R R R R both of which are substituted by 1, 2 or 3 substituents independently selected from R f , R i , nitro, cyano, —OH, —OR e , —OR i , —OC 2-6 alkylNR a R f , —OC 2-6 alkylOR f , —NR a R f , —NR a R i , —NR f C 2-6 alkylNR a R f , —NR f C 2-6 alkylOR f , naphthyl, —CO 2 R e , —C(═O)R e , —C(═O)NR a R f , —C(═O)NR a R i , —NR f C(═O)R e , —NR f C(═O)R i , —NR f C(═O)NR a R f , —NR f CO 2 R e , —C 1-8 alkylOR f , —C 1-6 alkylNR a R f , —S(═O) n R e , —S(═O) 2 NR a R f , —NR a S(═O) 2 R e , —NR a S(═O) 2 R c and —OC(═O)NR a R f , and additionally substituted by 0, 1, 2, 3, 4 or 5 substituents independently selected from Br, Cl, F and I; R R R R R R R R R