Patent ID: 9221784
Filing Date: 2015-12-29
Classification: A61P,C07D

Abstract:
1. A compound of the formula I, wherein A is selected from R R and either R R R one of the groups Z Ar is phenyl or an aromatic, 5-membered or 6-membered, monocyclic heterocycle which comprises one or two ring heteroatoms independently selected from N, O and S, which are all unsubstituted or substituted by one or more substituents independently selected from halogen, (C Het Het Het n is selected from the numbers 0, 1 and 2; wherein all alkyl groups are unsubstituted or substituted by one or more fluorine substituents; in any of its stereoisomeric forms or a mixture of stereoisomeric forms in any ratio, or a pharmaceutically acceptable salt thereof; provided that the compound of the formula I is not 6-chloro-4-cyclohexyl-4-phenyl-4H-benzo[1,3]dioxine-2-carboxylic acid, 6-chloro-4-cyclohexyl-4-phenyl-4H-benzo[1,3]dioxine-2-carboxylic acid methyl ester, or 6-chloro-4,4-dicyclohexyl-4H-benzo[1,3]dioxine-2-carboxylic acid.