Patent ID: 7241796
Filing Date: 2007-07-10
Classification: A61K,A61P,C07D,C07K

Abstract:
1. A compound of formula (IV): wherein: ring B is a bridged bicyclic ring system containing 6–12 carbon atoms, wherein ring B is saturated or partially unsaturated: or the ring system comprising ring B, together with the ring containing Z and the nitrogen atom, contains more than ten ring atoms; wherein ring B has up to 3 substituents selected independently from J; J is halogen, —OR′, —NO —COOR′ or —CON(R′) 2 , wherein R′ is independently selected from: R R Z is a carbon atom, —CHR—N—, —HN—CR— or —CHR—CHR—, —O—CHR, —S—CHR, —SO—CHR, —SO wherein R is aliphatic, aryl, aralkyl or cycloalkyl; R W is selected from: —C(O)OH; wherein each R two R wherein R each R each R V is a bond, —CH(R wherein R T is selected from: T is selected from: wherein: R wherein each T is optionally substituted with up to 3 J substituents; K is a bond, (C1–C12)-aliphatic, —O—, —S—, —NR n is 1–3.