Patent ID: 6541116
Filing Date: 2003-04-01
Classification: A61L,A61M,Y10S,Y10T

Abstract:
An intracorporeal medical device having a coating, the coating comprising:a) a polymerized base coat on the device, comprising: a binding component having at least a first functional group selected from the group consisting of isocyanate, aldehyde, oxirane, succinimide, maleimide, acetoacetoxy, aziridine, and carbodiimide; and a grafting component selected from the group consisting of vinyl, acrylate and allyl compounds, adhered to the device and bonded to the binding component; and b) a top coat on the base coat, comprising an agent selected from the group consisting of superoxide dismutase and a superoxide dismutase mimic, or a complex of the agent and a linking agent, the agent or the linking agent having a functional group which bonds with the binding component.