Patent ID: 6019967
Filing Date: 2000-02-01
Classification: A61K,A61P,A61Q,C07K,Y10S

Abstract:
A topically applicable therapeutic/cosmetic composition adopted for the therapeutic treatment or care of sensitive human skin, mucous membranes, and/or the scalp, comprising an effective therapeutically/cosmetically effective amount of at least one calcitonin gene related peptide (CGRP) antagonist and a therapeutically/cosmetically acceptable vehicle, diluent or carrier therefor, and which further comprises at least one normally skin-irritating bioactive agent, and wherein the relative ratio of the amounts of said CGRP antagonist to said bioactive agent in said composition are such that the irritation normally associated with said bioactive agent upon topical application to sensitive skin is inhibited or prevented by said CGRP antagonist.