Patent ID: 7420061
Filing Date: 2008-09-02
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A method of preparing a compound of Formula II wherein A is isoxazolyl, wherein A is unsubstituted or substituted with one or more radicals selected from acyl, halo, hydroxy, C 1 -C 10 -alkyl, C 1 -C 6 -haloalkyl, oxo, cyano, nitro, carboxyl, C 1 -C 6 -alkoxy, aminocarbonyl, C 1 -C 6 -alkoxycarbonyl, carboxy-C 1 -C 10 -alkyl, C 1 -C 10 -cyanoalkyl, C 1 -C 10 -alkylcarbonyloxyalkyl, phenyl and C 1 -C 6 -hydroxyalkyl; wherein R wherein R the method comprising reacting an unsubstituted sulfonamide with an acylating agent in the presence of base and a solvent.