Patent ID: 6028090
Filing Date: 2000-02-22
Classification: A61P,C07D

Abstract:
A method of treating thrombosis, cardiac infarction, stroke, osteoporosis, arteriosclerosis, inflammation or a tumor, comprising administering to a patient in need of such treatment an effective amount of a compound of formula I ##STR6## wherein R.sup.1 is a phenyl radical which is monosubstituted by H.sub.2 N--CH.sub.2 --, A.sub.2 N--CH.sub.2 --, H.sub.2 N--C(.dbd.NH)--, H.sub.2 N--C(.dbd.NH)--NH--, H.sub.2 N--C(.dbd.NH)--NH--CH.sub.2 --, HO--NH--C(.dbd.NH)-- or HO--NH--C(.dbd.NH)--NH--;X is --O--;B is ##STR7## A is C.sub.1-6 -alkyl; R.sup.2 is H, A, Li, Na, K, NH.sub.4 or benzyl;R.sup.3 is H or --(CH.sub.2).sub.n --COOR.sup.2 ;E is --CH--;m is 1, 2 or 3; andn is 0, 1, 2 or 3;or a physiologically compatible salt thereof.