Patent ID: 8802673
Filing Date: 2014-08-12
Classification: A61P,C07D

Abstract:
1. A compound of formula I wherein R m is 1 or 2; Ar is aryl or heteroaryl, selected from the group consisting of naphthyl, pyrimidinyl, benzothiazolyl, quinolinyl, quinazolinyl, benzo[d][1.3]dioxolyl, 5,6,7,8-tetrahydro-quinazolinyl, pyrazolyl, pyrazinyl, pyridazinyl, and 1,3,4-oxadiazolyl; Y is a bond, —CH R A is CR or N; and R is hydrogen, cyano, halogen or lower alkyl; R′ is hydrogen or halogen; with the proviso that when R′ is halogen, A is CH; B is CH or N; n is o, 1 or 2; and X is a bond, —CH or a pharmaceutical active acid addition salt thereof.