Patent ID: 6365605
Filing Date: 2002-04-02
Classification: A61P,C07D

Abstract:
A method for treating a living body afflicted with a condition requiring a D3 receptor ligand selected from depression, schizophrenia, psychoses, Parkinsons's disease, memory disorders, and disorders associated with drug abuse, comprising the step of administering to the living body an amount of a compound selected from those of formula (VIII): wherein:q represents 1, Z represents cyano or aminocarbonyl, R7 represents benzyl or acylamino-(C1-C6)-alkyl in which the alkyl moiety is linear or branched and in which the acyl group is benzoyl, naphthylcarbonyl, thienylcarbonyl, furylcarbonyl, pyrrolylcarbonyl or pyridinylcarbonyl, each of which is optionally substituted by one or more halogen or trihalomethyl, alkoxy, or hydroxy, the junction between the rings B and C is in the trans configuration, and their enantiomers, diastereoisomers and addition salts thereof with a pharmaceutically-acceptable acid or base.