Patent ID: 8236756
Filing Date: 2012-08-07
Classification: A61K,A61P,C07D,C07H,C07K

Abstract:
1. A method of treatment of a patient having a viral infection, which comprises administering to said patient a prodrug comprising a therapeutic compound D linked to an oligopeptide having a general structure H—[X—Y] n , wherein X is an amino acid, wherein n is selected from 1, 2, 3, 4 and 5; and wherein Y is an amino acid selected from the group consisting of proline, hydroxyproline, and dihydroxyproline; and wherein a binding via an amide occurs between said oligopeptide H-[X—Y] wherein said therapeutic compound D is an antiviral drug other than a drug with inhibitory activity on CD26/DPPIV enzymatic activity; and wherein said therapeutic compound D is not an amino acid, a peptide or a protein.