Patent ID: 7744920
Filing Date: 2010-06-29
Classification: A61K,A61P

Abstract:
1. A method for the treatment of an inflammatory associated condition in a subject, provided that the condition is not associated with a neurodegenerative disease or disorder, the method comprises administering to the subject in need thereof an amount of a GC or GC derivative encapsulated in a liposome and essentially retained in the liposome for 6 months under storage conditions at 4° C., wherein the liposome comprises a lipopolymer and liposome forming lipids, the amount of the GC or GC derivative being effective to treat the inflammatory associated condition, wherein the GC or GC derivative is selected from the group consisting of: i) an amphipathic weak base GC or GC derivative having a pKa equal or below 11 and a logD at pH 7 in the range between about −2.5 and about 1.5; and ii) an amphipathic weak acid GC or GC derivative having a pKa above 3.5 and a logD at pH 7 in the range between about −2.5 and about 1.5 wherein at least inflammation is treated.