Patent ID: 6818405
Filing Date: 2004-11-16
Classification: A61K,A61P,C07K,Y10S

Abstract:
A method for treating a disease caused by a mineral imbalance, comprising administering to a mammal a pharmaceutically active amount of:(A) an SMR1 protein comprising SEQ ID NO:14, (B) a fragment of the SMR1 protein comprising SEQ ID NO:14, (C) a maturation product of the SMR1 protein comprising SEQ ID NO:1, SEQ ID NO:7 or SEQ ID NO:12, or (D) a derivative of the SMR1 protein of(A), the fragment of(B) or the maturation product of (C) that comprises at least one modified amino acid residue, which has improved stability and which retains the mineral imbalance modulating activity of the protein of (A), the fragment of (B) or the maturation product of (C), and wherein said protein, fragment, maturation product or derivative modulates mineral ion concentration.