Patent ID: 8969366
Filing Date: 2015-03-03
Classification: A61K,A61N,A61P,C07D

Abstract:
1. A method for treating a disease selected from the group consisting of melanoma, stomach cancer, liver cancer, colorectal cancer, pancreatic cancer, breast cancer, ovarian cancer, lung cancer, thyroid cancer, cervical cancer, myeloma and leukemia, which comprises administering to a mammal in need thereof an effective amount of a compound of formula (I): wherein: R1 is hydrogen or R1′, wherein R1′ is R2 is hydrogen or R2′, wherein R2′ is R3 is NH2 or R3′, wherein R3′ is L wherein L L L A is direct bond, O, OCH2, OCO, CON(Y), CON(Y)O, CON(Y)N(Y), CON(Y)SO Y is hydrogen or an optionally substituted straight or branched (C R5 is hydrogen or an optionally substituted group selected from straight or branched (C R6 is selected from hydrogen, halogen, trifluoromethyl, (C R4 is an optionally substituted group selected from straight or branched C with the proviso that only one of R1, R2 and R3 is respectively R1′, R2′ or R3′ as defined above, and pharmaceutically acceptable salts.