Patent ID: 6534638
Filing Date: 2003-03-18
Classification: A61K,A61P,C07H,C07K,C12N

Abstract:
An isolated nucleic acid comprising at least one nucleotide sequence which encodes a helminth aminopeptidase or an antigenic portion thereof, said nucleic acid selected from the group consisting of i) any sequence of SEQ ID NOs:1-15 or 9-21, ii) a sequence fully complementary to said sequence of (i), iii) a portion of said sequence of (i) wherein said portion of said sequence encodes an antigenic peptide of said helminth aminopeptidase, and (iv) a sequence which hybridizes with said sequence of (i) or (ii) under conditions of 2Ã—SSC, 65Â° C. (where SSC=0.15 M NaCl, 0.015 M sodium citrate, pH 7.2) and which has at least 60% identity with said sequence of (i).