Patent ID: 6821974
Filing Date: 2004-11-23
Classification: A61P,C07D

Abstract:
A particulate-free and plasma-labile hydralazine composition comprising compound having the formula: or a compound having the formula: where R1 and R2 are independently H, substituted or unsubstituted branched chain alkyl having from 3 to about 7 carbon atoms, unsubstituted cycloalkyl, substituted or unsubstituted aralkyl, substituted or unsubstituted alkylcycloalkyl, substituted or unsubstituted aryl or substituted cycloalkyl with the proviso that at least one of R1 and R2 is hydrogen or R1 and R2 together form part of an unsubstituted cycloalkyl having from about 4 of about 7 carbon atoms; where R3 is a branched or straight chain alkyl having from 2 to about 7 carbon atoms, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted alkylcycloalkyl or a group having the formula (CH2)nCOOH where n is from 3 to about 7 in a pharmaceutically acceptable salt or diluent.