Patent ID: 7645760
Filing Date: 2010-01-12
Classification: A61P,C07D

Abstract:
1. A compound of formula I, or a pharmaceutically acceptable salt or ester thereof, wherein R wherein X is a linker having 1, 2, 3 or 4 atom or independently selected from N, C, or S, and wherein when said linker has 2 or more C atoms the linker may have 1 or more C═C or C≡C bonds; wherein any of said atoms has up to 2 optional substituents selected from hydrogen, oxo, cyano, halo, nitro or optionally substituted oxy, lower alkyl, lower alkyenyl, lower alkynyl, carbonyl, sulfur amino; sulfinyl, sulfonyl; R R R R R the optional substituents on X are one or more independently selected from the group consisting of hydrogen, oxo, cyano, halo, nitro or optionally substituted oxy, lower alkyl, lower alkyenyl, lower alkynyl, lower alkynyl, amino, carbonyl, sulfur, sulfinyl, sulfonyl; wherein the optionally substituted substituents are optionally substituted once or more by a substituent independently selected from the group consisting of hydrogen, oxo, cyano, halo, nitro, oxy, lower alkyl, lower alkyenyl, lower alkynyl, amino, sulfur, cycloalkyl, heterocyloalkyl, aryl; the optional substituents on R the optional substituents on R the optional substituents on R wherein the optionally substituted substituents are optionally substituted once or more by a substituent independently selected from the group consisting of hydrogen, oxo, cyano, halo, nitro or optionally substituted oxy, lower alkyl, lower alkyenyl, lower alkynyl, carbonyl, amino, sulfur, cycloalkyl, heterocycloalkyl, aryl; the optional substituents on R wherein the optionally substituted substituents are optionally substituted once or more by a substituent independently selected from the group consisting of hydrogen, oxo, cyano, halo, nitro or optionally substituted oxy, lower alkyl, lower alkyenyl, lower alkynyl, carbonyl, amino, sulfur, cycloalkyl, heterocycloalkyl, aryl; the optional substituents on R wherein the optionally substituted substituents are optionally substituted once or more by a substituent independently selected from the group consisting of hydrogen, oxo, hydroxyl, cyano, halo, nitro or optionally substituted oxy, lower alkyl, lower alkyenyl, lower alkynyl, carbonyl, amino, sulfur, cycloalkyl, heterocycloalkyl, or aryl.