Patent ID: 6566079
Filing Date: 2003-05-20
Classification: B82Y,C12Q,G01N,H01J

Abstract:
A method of screening ligands for the ability to bind to a protein of interest, comprising:(a) contacting said protein of interest with a ligand, wherein said protein of interest or said ligand is contained within a molecular binding region which is electromagnetically coupled to a portion of a signal path, said signal path operable to support a signal propagated at one or more frequencies in the range from 10 MHz to 1000 GHz and comprising a waveguide or resonant cavity; and (b) detecting a response signal at one or more frequencies in said range from 10 MHz to 1000 GHz indicating a binding complex formed between said protein of interest and said ligand, wherein said response signal results from coupling of said propagated signal to said protein, said ligand, or said complex.