Patent ID: 6251382
Filing Date: 2001-06-26
Classification: A61K

Abstract:
A polymer conjugate of the formula: ##STR15##wherein:D is a biologically active compound having an available hydroxyl group which undergoes a substitution reaction,R.sub.1 is a polymer residues;R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.9, R.sub.10, R.sub.11, R.sub.12, R.sub.9', R.sub.10', R.sub.11', and R.sub.12' are independently selected from hydrogen, C.sub.1-6 substituted cycloalkyls, aryls, substituted aqyls, aralkyls, C.sub.1-6 heteroalkyls, substituted C.sub.1-6 heteroalkyls, C.sub.1-6 alkoxy, phonoxy and C.sub.1-6 hoteroakoxy;p is a positive integer;m and n are independently selected positive integers; andY, Y.sub.2, Y.sub.3, Y', Y.sub.2' and Y.sub.3' are independently selected from O, S, NR.sub.2.