Patent ID: 7067514
Filing Date: 2006-06-27
Classification: A61K,A61P,C07D

Abstract:
1. A method for treating an interleukin-12 overproduction-related disorder, wherein the disorder is rheumatoid arthritis, sepsis, Crohn's disease, multiple sclerosis, psoriasis, or insulin-dependent diabetes mellitus, comprising administering to a subject in need thereof the compound of formula (I): wherein R aryl, or heteroaryl; each of R R n is 0, 1, 2, 3, 4, 5, or 6; X is O, S, S(O), S(O Y is a covalent bond, CH Z is N or CH; one of U and V is N, and the other is CR W is O, S, S(O), S(O in which each of R