Patent ID: 7794717
Filing Date: 2010-09-14
Classification: A61K,A61P,C07K

Abstract:
1. A method of treating a disease or disorder which is improved, ameliorated or inhibited by removal, inhibition or reduction of human interleukin-4 (hIL-4) activity, said method comprising administering to a patient in need thereof an antibody or antigen-binding fragment thereof which specifically binds to a hIL-4 receptor, wherein said antibody comprises a heavy chain variable region (HCVR) comprising the three heavy chain CDRs (HCDR1, HCDR2 and HCDR3) from SEQ ID NO:581, and a light chain variable region (LCVR) comprising the three light chain CDRs (LCDR1, LCDR2 and LCDR3) from SEQ ID NO:417, wherein the disease or disorder is asthma.