Patent ID: 7879356
Filing Date: 2011-02-01
Classification: A61L,A61P,C08G

Abstract:
1. A biodegradable or bioerodible polymeric composition consisting essentially of hydrophilically crosslinked AB diblocks, where A is a polyester unit derived from the polymerization of monomers selected from the group consisting of lactic acid, lactide, glycolic acid, glycolide, β-propiolactone, ε-caprolactone, δ-glutarolactone, δ-valerolactone, β-butyrolactone, pivalolactone, α,α-diethylpropiolactone, ethylene carbonate, trimethylene carbonate, γ-butyrolactone, p-dioxanone, 1,4-dioxepan-2-one, 3-methyl-1,4-dioxane-2,5-dione, 3,3,-dimethyl-1-4-dioxane-2,5-dione, cyclic esters of α-hydroxybutyric acid, α-hydroxyvaleric acid, α-hydroxyisovaleric acid, α-hydroxycaproic acid, α-hydroxy-α-ethylbutyric acid, α-hydroxyisocaproic acid, α-hydroxy-α-methyl valeric acid, α-hydroxyheptanoic acid, α-hydroxystearic acid, α-hydroxylignoceric acid, salicylic acid and mixtures, thereof and B is a polyoxyalkylene polymer which is end-capped with a non-reactive group, said AB diblock being further reacted with one or more water soluble or water dispersible crosslinking agents to produce crosslinked diblock polymers wherein said crosslinking agents comprise (poly)ethylene oxide chains or (poly)ethylene oxide-co-(poly)propylene oxide chains.