Patent ID: 7163958
Filing Date: 2007-01-16
Classification: A61P,C07C,C07D

Abstract:
1. A compound of Formula (I), or a pharmaceutically acceptable salt thereof; wherein the compound of Formula (I) is:  wherein: s is an integer of 0 or 1; X is: (1)—Y—(CR (2)—Y—(CR (3)—Y—(CR (4)—Y—(CR (5) —Y—(CR (6) —Y—(CR (7) —Y—(CR (8) —Y—(CR (9) —Y—(CR (10) —Y—(CR R V is —C(O)-T-, -T-C(O)—, -T-C(O)-T or T-C(O)—C(O)-T; W is a covalent bond or a carbonyl group; T at each occurrence is independently an oxygen, (S(O) R p at each occurrence is independently an integer from 1 to 6; q at each occurrence is independently an integer from 1 to 3; o at each occurrence is independently an integer from 0 to 2; Y is oxygen or sulfur (—S—); B is either phenyl or (CH Q′ is a cycloalkyl group, a heterocyclic ring or an aryl group; Z is (═O), (═N—OR M and M′ are each independently —O R with the proviso that for X in the compounds of Formulas (I): when Y is oxygen or sulfur in Formula 5, and W is a covalent bond, at least one R when Y is oxygen or sulfur in Formula 7, T is N(CH when Y is oxygen or sulfur in Formula 7, W is a covalent bond, T is oxygen and o is the integer 1, at least one R