Patent ID: 7596455
Filing Date: 2009-09-29
Classification: A61P,C07K

Abstract:
1. A method of designing a compound that has a 3-dimensional structure that mimics the 3-dimensional surface structure of human IGF-1 as set forth in SEQ ID NO: 1 comprising the steps of: (a) determining the 3-dimensional structure of the human IGF-1 (SEQ ID NO: 1) by X-ray diffraction of an orthorhombic crystal of said human IGF-1 that has approximately the following cell constants a=31.831 Å, b=71.055 Å, c=65.995 Å, and a space group of C222 (b) designing a compound that has a 3-dimensional structure that mimics the 3-dimensional surface structure of the human IGF-1.