Patent ID: 8513293
Filing Date: 2013-08-20
Classification: A61P,C07D

Abstract:
1. A method of alleviating or inhibiting the progress of a hyperproliferative disorder in a mammal in need thereof, comprising administering to said mammal an effective amount of 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxyethoxy)-amide, or a pharmaceutically acceptable salt thereof, in combination with an effective amount of an anti-tumour agent selected from the group consisting of mitotic inhibitors, alkylating agents, anti-metabolites, intercalating antibiotics, growth factor inhibitors, cell cycle inhibitors, enzyme inhibitors, topoisomerase inhibitors, biological response modifiers, anti-hormones, angiogenesis inhibitors and anti-androgens, wherein said hyperproliferative disorder is selected from the group consisting of lung cancer, squamous cell cancer, pancreatic cancer, breast cancer, head cancer, neck cancer, prostate cancer, colorectal cancer and melanoma.