Patent ID: 8128945
Filing Date: 2012-03-06
Classification: A61K,B82Y,Y10S

Abstract:
1. A drug delivery system for targeting estrogen receptor over-expressing cells, comprising: a plurality of nanoparticles, wherein said nanoparticles consist of one or more of the compounds selected from the group consisting of: lipids, surfactants, charged peptides, proteins, and polymers; active ingredients, wherein said active ingredients are encapsulated inside said nanoparticles or wherein said active ingredients form a complex with said nanoparticles; and a plurality of targeting ligands having a structure of the formula (I): wherein n is an integer less than 10 and NP represents said nanoparticles, and wherein said plurality of targeting ligands binds to estrogen receptor, and upon binding to estrogen receptor delivers the active ingredient to the estrogen receptor over-expressing cells.