Patent ID: 6573264
Filing Date: 2003-06-03
Classification: A61K,A61P,C07D

Abstract:
A substituted piperazine compound having the following formula: wherein m=1, 2, or 3;q=NH, O, or S; R1, R2, R3, R4 and R5 are each independently selected from the group consisting of hydrogen, OR20 and C1-15 straight or branched alkyl; R6, R7 and R8 are each independently hydrogen; R9, R10, R11, R12, R13, R14, R15 and R16 are each independently selected from the group consisting of hydrogen and C1-4 straight or branched alkyl, or wherein R9 and R10 may together form a carbonyl, or R11 and R12 may together form a carbonyl, or R13 and R14 may together form a carbonyl, or R15 and R16 may together form a carbonyl; R17 is selected from the group consisting of benzoxazolyl, benzothiazolyl, quinoxalinyl, pyridinyl, quinolinyl, isoquinolinyl, and indolyl, wherein each group is optionally substituted with from 1 to 3 substituents selected from the group consisting of CON(R20)2, C1-15 straight or branched alkyl and aryl, wherein the aryl substituents are optionally substituted with 1 substituent selected from the group consisting of CF3; and R20 is hydrogen.