Patent ID: 6815465
Filing Date: 2004-11-09
Classification: A61P,C07D

Abstract:
A compound having the formula (I): wherein:R is â€”COOR1, â€”CONR2R3 or CONR4CONR4R5; R1 is: C1-6 alkyl, substituted by a member selected from the group consisting of: hydroxyl; amino; di(C1-4 alkyl)amino; a 5- to 8-membered saturated, nitrogen-containing heterocyclic ring, optionally having, in addition to the required nitrogen ring atom, an oxygen ring atom or one or two further nitrogen ring atoms; and a 5- or 6-membered nitrogen-containing aromatic heterocyclic ring optionally having, in addition to the required nitrogen ring atom, an oxygen ring atom or one or two further nitrogen ring atoms; or C3-6 cycloalkyl; R2 and R3 are identical or different and independently from each other represent: hydrogen; C1-6 alkyl, optionally substituted by a member selected from the group consisting of: halogen; hydroxyl; amino; C2-5 alkoxycarbonyl; di(C1-4 alkyl)amino; a 5- to 8-membered saturated, nitrogen-containing heterocyclic ring, optionally having, in addition to the required nitrogen ring atom, an oxygen ring atom or one or two further nitrogen ring atoms; a phenyl ring; and a 5- or 6-membered aromatic heterocyclic ring having an oxygen ring atom and/or a nitrogen ring atom; or a 5- or 6-membered cycloalkyl ring or a 5- or 6-membered aromatic heterocyclic ring having an oxygen ring atom and/or a nitrogen ring atom; and R4 and R5 are identical or different and independently from each other represent hydrogen, C1-6 alkyl, C3-6 cycloalkyl or phenyl; or a tautomer, solvate, mixture or acid addition salt thereof.