Patent ID: 8980898
Filing Date: 2015-03-17
Classification: A61K,A61P,C07D

Abstract:
1. A compound represented by formula (I): and racemates, enantiomers, diastereomers, tautomers, polymorphs, pseudopolymorphs and pharmaceutically acceptable salts, thereof, wherein: X is hydrogen, halogen, trifluoromethyl, lower alkyl, unsubstituted or substituted phenyl, lower alkyl-thio, phenyl-lower alkyl-thio, lower alkyl-sulfonyl, or phenyl-lower alkyl-sulfonyl; Y is hydrogen, hydroxyl, mercapto, lower alkoxy, lower alkyl-thio, halogen, lower alkyl, unsubstituted or substituted mononuclear aryl, or —N(R R each R R A A each R each o is, independently, an integer from 0 to 10; each p is, independently, an integer from 0 to 10; with the proviso that the sum of o and p in each contiguous chain is from 1 to 10; each x is, independently, O, NR each R each R wherein when two R each R each R each R each R each Z is, independently, —(CHOH)—, —C(═O)—, —(CHNR each R each R each R each g is, independently, an integer from 1 to 6; each m is, independently, an integer from 1 to 7; each n is, independently, an integer from 0 to 7; each -Het- is, independently, —N(R each Link is, independently, —O—, —(CH each CAP is