Patent ID: 9121917
Filing Date: 2015-09-01
Classification: G01R

Abstract:
1. A method for obtaining a magnetic resonance image (MRI) or spectrum, comprising: performing a chemical exchange saturation transfer (CEST) labeling experiment or a conventional magnetization transfer (MT) labeling experiment of a subject using an MRI machine; constructing a multi-parametric varied saturation scheme applied by the MRI machine for performing the CEST labeling experiment or the conventional MT labeling experiment of the subject; generating data from the CEST or conventional MT MRI experiment; transmitting the data to a data processing unit; processing the data to generate a visual representation of the data; processing the data generated from the CEST experiment separately from other sources of signal loss that create image contrast; processing the data generated for each of a parameter of the multi-parametric saturation scheme separately; processing asymmetry in a magnetization transfer ratio for the data generated from the CEST experiment for each of the parameters of the multi-parametric saturation scheme, such that a difference between the magnetization transfer ratio for each of the parameters of the multi-parametric saturation scheme results in a transformed signal in a frequency domain for the multi-parametric saturation scheme; and, generating a second visual representation of the data based on the processing of the data.