Patent ID: 9128057
Filing Date: 2015-09-08
Classification: B01L,G01N

Abstract:
1. A dual mode genetic testing platform comprising: a) a microfluidic platform; b) a thermocycler system thermally coupled thereto; and c) a multi-channel optical detector coupled thereto, said microfluidic platform comprising: a first analysis module comprising a plurality of first reaction vessels each comprising a contrast enhancing reagent and a first composition of PCR reagents configured for a copy number analysis testing, each of said first reaction vessels being optically coupled to a first channel of the multi-channel optical detector, wherein said first channel further comprises first electronic drivers operable for capturing a plurality of discrete optical signals over the course of an extended period of time; a second analysis module comprising a plurality of second reaction vessels each comprising a plurality of distinct optical reporters and a second composition of PCR reagents configured for a genotype testing, each of said second reaction vessels being optically coupled to a second channel of the multi-channel optical detector, wherein said second channel further comprises second electronic drivers configured to capture a single optical signal at a discrete moment in time; wherein said microfluidic platform is configured to remain in physical contact with said thermocycler system throughout a prescribed set of thermocycles.