Patent ID: 6075126
Filing Date: 2000-06-13
Classification: C07C,C07D,C07F,C07K,G01N,Y10S

Abstract:
A conjugate of a biologically active species with a reagent, the conjugate having the general formula of General Formula II: ##STR22## wherein group Z comprises a spacer selected from a saturated or unsaturated chain of up to about 6 carbon equivalents in length, an unbranched saturated or unsaturated chain of from about 6 to 18 carbon equivalents in length with at least one of intermediate amide or disulfide moieties, and a polyethylene glycol chain of from about 3 to 12 carbon equivalents in length;wherein group Q is one of amide, ether and thioether linkages; andwherein BAS is a biologically active species.