Patent ID: 6051582
Filing Date: 2000-04-18
Classification: C07D

Abstract:
A compound of the formula: ##STR92## or a pharmaceutically acceptable salt or solvate thereof, wherein: a represents N;R.sup.1 and R.sup.3 are the same or different and each represents halo;R.sup.2 and R.sup.4 are each independently selected from H and halo, provided that at least one of R.sup.2 and R.sup.4 is H;each dotted line (---) represents an optional bond;X is C when the optional bond to X is present, or CH when the optional bond to X is absent;T is a substituent selected from: ##STR93## Z represents O; R represents --SO.sub.2 R.sup.10 ;R.sup.5 represents alkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, cycloalkyl, OR.sup.12, NR.sup.12 H, SH, SR.sup.12, SOR.sup.12 (where R.sup.12 is not H), or SO.sub.2 R.sup.12 (where R.sup.12 is not H); andR.sup.10 represents alkyl;R.sup.12 is selected from H, alkyl, aryl, aralkyl, heteroaryl, heteroarylalkyl, or heterocycloalkyl.