Patent ID: 8226983
Filing Date: 2012-07-24
Classification: A61K,A61P,Y10T

Abstract:
1. A method for producing poor water solubility organic compound fine particles for medical use comprising: mixing a poor water solubility organic compound with at least one physiologically acceptable salt in the amount of 1- to 100-fold with respect to a mass of the poor water solubility organic compound and a physiologically acceptable polyol; wet-milling the poor water solubility organic compound by the physiologically acceptable salt; and removing the at least one physiologically acceptable salt and the physiologically acceptable polyol after the wet-milling, wherein the poor water solubility organic compound has a melting point or a decomposition point in the range of 80 to 350 degrees C., and the wet-milled poor water solubility organic compound fine particles maintain its crystal form as the poor water solubility organic compound has before the wet-milling process.