Patent ID: 7935715
Filing Date: 2011-05-03
Classification: A61P,C07C,C07D

Abstract:
1. A compound chosen from 2-Methyl-N-pyridin-3-yl-2-(4-trifluoromethyl-benzenesulfonyl)-propionamide 2-(4-Chloro-benzenesulfonyl)-2-methyl-N-(4-methyl-pyridin-2-yl)-propionamide 2-(4-Chloro-benzenesulfonyl)-2-methyl-N-(5-methyl-pyridin-2-yl)-propionamide 2-(4-Chloro-benzenesulfonyl)-2-methyl-N-(6-methyl-pyridin-2-yl)-propionamide 2-(4-Chloro-benzenesulfonyl)-2-methyl-N-(5-trifluoromethyl-pyridin-2-yl)-propionamide 2-(4-Chloro-benzenesulfonyl)-2-methyl-N-(4-trifluoromethyl-pyridin-2-yl)-propionamide 2-(4-Chloro-benzenesulfonyl)-N-(4-ethyl-pyridin-2-yl)-2-methyl-propionamide 2-(4-Chloro-benzenesulfonyl)-2-methyl-N-(5-phenyl-pyridin-2-yl)-propionamide 2-(4-Chloro-benzenesulfonyl)-2-methyl-N-(6-trifluoromethyl-pyridin-2-yl)-propionamide 2-(4-Chloro-benzenesulfonyl)-N-(6-methoxy-pyridin-3-yl)-2-methyl-propionamide 2-(4-Chloro-benzenesulfonyl)-2-methyl-N-pyridin-3-yl-propionamide 2-(4-Chloro-benzenesulfonyl)-2-methyl-N-(6-phenoxy-pyridin-3-yl)-propionamide 2-(4-Chloro-benzenesulfonyl)-2-methyl-N-(3-trifluoromethyl-pyridin-2-yl)-propionamide 2-(4-Chloro-benzenesulfonyl)-2-methyl-N-pyridin-2-yl-propionamide 2-Methyl-2-(4-trifluoromethyl-benzenesulfonyl)-N-(5-trifluoromethyl-pyridin-2-yl)-propionamide 3-Methyl-2-(4-trifluoromethyl-benzenesulfonyl)-N-(5-trifluoromethyl-pyridin-2-yl)-butyramide 2-(4-Bromo-benzenesulfonyl)-2-methyl-N-(5-trifluoromethyl-pyridin-2-yl)-propionamide 2-(3-Fluoro-4-methoxy-benzenesulfonyl)-2-methyl-N-(5-trifluoromethyl-pyridin-2-yl)-propionamide 2-(4-Bromo-benzenesulfonyl)-2-methyl-N-(6-trifluoromethyl-pyridin-2-yl)-propionamide 2-(3-Fluoro-4-methoxy-benzenesulfonyl)-2-methyl-N-(6-trifluoromethyl-pyridin-2-yl)-propionamide 2-(3-Fluoro-4-methyl-benzenesulfonyl)-2-methyl-N-(6-trifluoromethyl-pyridin-2-yl)-propionamide 3-Methyl-2-(4-trifluoromethyl-benzenesulfonyl)-N-(6-trifluoromethyl-pyridin-2-yl)-butyramide 2-(4-Cyano-benzenesulfonyl)-2-methyl-N-(5-trifluoromethyl-pyridin-2-yl)-propionamide 2-(3-Fluoro-4-methyl-benzenesulfonyl)-2-methyl-N-(5-trifluoromethyl-pyridin-2-yl)-propionamide 4-(4-Trifluoromethyl-benzenesulfonyl)-tetrahydro-pyran-4-carboxylic acid (6-trifluoromethyl-pyridin-2-yl)-amide 1-(4-Trifluoromethyl-benzenesulfonyl)-cyclopropanecarboxylic acid (4-trifluoromethyl-pyridin-2-yl)-amide 1-(4-Trifluoromethyl-benzenesulfonyl)-cyclopropanecarboxylic acid (5-trifluoromethyl-pyridin-2-yl)-amide 1-(4-Trifluoromethyl-benzenesulfonyl)-cyclopropanecarboxylic acid (6-trifluoromethyl-pyridin-2-yl)-amide 2-Methyl-2-(toluene-4-sulfonyl)-N-(6-trifluoromethyl-pyridin-2-yl)-propionamide 2-Methyl-2-(toluene-4-sulfonyl)-N-(5-trifluoromethyl-pyridin-2-yl)-propionamide 2-Benzenesulfonyl-2-methyl-N-(6-trifluoromethyl-pyridin-2-yl)-propionamide 2-Benzenesulfonyl-2-methyl-N-(5-trifluoromethyl-pyridin-2-yl)-propionamide 1-(4-Chloro-benzenesulfonyl)-cyclopropanecarboxylic acid (5-trifluoromethyl-pyridin-2-yl)-amide 1-(4-Chloro-benzenesulfonyl)-cyclopropanecarboxylic acid (4-trifluoromethyl-pyridin-2-yl)-amide 2-(3-Fluoro-benzenesulfonyl)-2-methyl-N-(5-trifluoromethyl-pyridin-2-yl)-propionamide 2-(2-Fluoro-benzenesulfonyl)-2-methyl-N-(5-trifluoromethyl-pyridin-2-yl)-propionamide 2-(4-Chloro-2-fluoro-benzenesulfonyl)-2-methyl-N-(5-trifluoromethyl-pyridin-2-yl)-propionamide 2-(4-Chloro-2-fluoro-benzenesulfonyl)-2-methyl-N-(6-trifluoromethyl-pyridin-2-yl)-propionamide 2-(4-Chloro-2-fluoro-benzenesulfonyl)-2-methyl-N-(4-trifluoromethyl-pyridin-2-yl)-propionamide 2-(2-Fluoro-4-methyl-benzenesulfonyl)-2-methyl-N-(5-trifluoromethyl-pyridin-2-yl)-propionamide 2-(4-Cyano-2-fluoro-benzenesulfonyl)-2-methyl-N-(5-trifluoromethyl-pyridin-2-yl)-propionamide 2-(4-Fluoro-benzenesulfonyl)-2-methyl-N-(5-trifluoromethyl-pyridin-2-yl)-propionamide 2-(4-Fluoro-benzenesulfonyl)-2-methyl-N-(6-trifluoromethyl-pyridin-2-yl)-propionamide 2-(2,5-Difluoro-benzenesulfonyl)-2-methyl-N-(5-trifluoromethyl-pyridin-2-yl)-propionamide 2-(2,5-Difluoro-benzenesulfonyl)-2-methyl-N-(6-trifluoromethyl-pyridin-2-yl)-propionamide N-(5-sec-Butyl-pyridin-2-yl)-2-(4-chloro-benzenesulfonyl)-2-methyl-propionamide 2-(4-Methanesulfonyl-benzenesulfonyl)-2-methyl-N-(5-methyl-pyridin-2-yl)-propionamide 2-[(4-methoxyphenyl)sulfonyl]-2-methyl-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide 2-[(2,4-difluorophenyl)sulfonyl]-2-methyl-N-[5-(trifluoromethyl)pyridin-2-yl]propanamide 2-[(2,4-difluorophenyl)sulfonyl]-2-methyl-N-[4-(trifluoromethyl)pyridin-2-yl]propanamide 2-[(2,4-difluorophenyl)sulfonyl]-2-methyl-N-[6-(trifluoromethyl )pyridin-2-yl]propanamide 2-methyl-2-{[4-(methylsulfonyl)phenyl]sulfonyl}-N-[5-(trifluoromethyl)pyridin-2-yl]propanamide 2-methyl-2-{[4-(methylsulfonyl)phenyl]sulfonyl}-N-[4-(trifluoromethyl)pyridin-2-yl]propanamide N-(4-ethylpyridin-2-yl)-2-methyl-2-{[4-(methylsulfonyl)phenyl]sulfonyl}propanamide 2-methyl-2-{[4-(methylsulfonyl)phenyl]sulfonyl}-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide 2-[(4-chloro-2-fluorophenyl)sulfonyl]-N-(4-ethylpyridin-2-yl)-2-methylpropanamide 2-[(4-chloro-2-fluorophenyl)sulfonyl]-2-methyl-N-(5-methylpyridin-2-yl)propanamide 2-methyl-N-[3-(trifluoromethyl)phenyl]-2-{[6-(trifluoromethyl)pyridin-3-yl]sulfonyl}propanamide N-(4-tert-butylphenyl)-2-methyl-2-{[6-(trifluoromethyl)pyridin-3 -yl]sulfonyl}propanamide 2-methyl-N-[4-(trifluoromethyl)phenyl]-2-{[6-(trifluoromethyl)pyridin-3-yl]sulfonyl}propanamide N-(3-tert-butylphenyl)-2-methyl-2-{[6-(trifluoromethyl)pyridin-3 -yl]sulfonyl}propanamide and N-(2-tert-butylpyridin-4-yl)-2-[(4-chlorophenyl)sulfonyl]-2-methylpropanamide or a tautomer or pharmaceutically acceptable salt thereof.