Patent ID: 6380395
Filing Date: 2002-04-30
Classification: A61P,C07D

Abstract:
A compound of the formula wherein:B1 and B2 are selected from the group consisting of H, or OR6; R1, R2, R3, and R4, are selected from H, lower alkyl; R5 is selected from the group consisting of H, alkyl, substituted alkyl; R8 is heterocyclo; R9 is hydrogen or lower alkyl; R6 is hydrogen or alkyl; M is CR10R11; R10 and R11 are selected from the group consisting of H, halogen, alkyl, substituted alkyl, aryl, substituted aryl, cycloalkyl, heterocyclo, R12C&boxH;O, R13OC&boxH;O, R14NHC&boxH;O, hydroxy, O-alkyl or O-substituted alkyl, NR15R16; R12, R13, R14, R15, R17, R18 and R19 are selected from the group consisting of H, alkyl, substituted alkyl, aryl, acyl or substituted aryl; R16 is selected from the group consisting of H, alkyl, substituted alkyl, aryl, substituted aryl, cycloalkyl, heterocyclo, R17C&boxH;O, R18OC&boxH;O, R19SO2, hydroxy, O-alkyl, or O-substituted alkyl: and any salts, solvates or hydrates thereof.