Patent ID: 7855063
Filing Date: 2010-12-21
Classification: A61K,A61P,C12N,C12Y,G01N

Abstract:
1. A composition-of-matter comprising a crystal of a glucocerebrosidase polypeptide, wherein the crystal has unit cell dimensions of a=about 107.7 angstroms, b=about 285.2 angstroms and c=about 91.8 angstroms and a crystal space group of C222 1 , wherein the amino acid sequence of said glucocerebrosidase polypeptide consists of SEQ ID NO: 1, and wherein the amino acid sequence is glycosylated at Asn19 and unglycosylated at Asn59, Asn146 and Asn270 of SEQ ID NO:1.