Patent ID: 6025394
Filing Date: 2000-02-15
Classification: A61K,A61P

Abstract:
A method of treating acne comprising administering to the patient a physiologically effective amount of a compound of the formula: ##STR2## wherein R.sub.1 is independently selected in each instance from the group consisting of hydrogen, halogen, lower alkoxy, hydroxy, lower alkyl, lower alkyl mercapto, lower alkylsulfonyl, lower alkylamino, di-lower alkyl amino, amino, nitro, nitrile, lower alkyl carboxylate, --CO.sub.2 H, and sulfonamido;R.sub.2 is selected from the group consisting of hydrogen and lower alkyl;R.sub.3 is selected from the group consisting of hydrogen, lower alkyl, hydroxy, and amino;R.sub.4 is selected from the group consisting of --COM and CH.sub.2 OH wherein M is selected from the group consisting of hydroxy, substituted lower alkoxy, amino, alkylamino, dialkylamino, N-morpholino, hydroxyalkylamino, polyhydroxyamino, dialkylaminoalkylamino, aminoalklyamino, and the group OMe, wherein Me is a cation;R.sub.5 is an alkyl sulfonyl; and n is an integer from 0 to four,or a pharmaceutically acceptable salt thereof.