Patent ID: 9144569
Filing Date: 2015-09-29
Classification: A61D,A61K,A61P

Abstract:
1. A method of regulating ovarian follicle development and/or ovulation in a mammal, comprising: (a) administering an amount of an aromatase inhibitor effective to influence ovarian follicle wave emergence in said mammal; (b) administering a luteolytic dose of a prostaglandin or a suppressive dose of a gonadotropin-agonist or antagonist to prevent corpus luteum (CL) formation; and (c) administering an ovulatory dose of a compound selected from the group consisting of gonadotropin-releasing hormone (GnRH), a GnRH analogue, luteinizing hormone (LH), and an LH analogue wherein said prostaglandin is PGF wherein said GnRH, GnRH analogue, LH, or LH analogue is administered within 48 hours after the last day of said aromatase inhibitor treatment.