Patent ID: 7279472
Filing Date: 2007-10-09
Classification: A61P,C04B,C07D

Abstract:
1. A compound of formula (Ia) or (Ib): wherein: Het is piperidinyl, substituted or unsubstituted with one or more R R R R each R R or R or R R  wherein W is —S(O) n — or —N—C(O)—, n is 0, 1 or 2 and wherein each ring is optionally independently substituted by one or two R 7 ; each R C1-5 alkyl chain optionally interrupted by one or two N, O or S(O) aryl, aryloxy, aroyl, furanyl, thienyl, pyrrolyl, imidazolyl, pyridinyl, pyrimidinyl, C1-5 alkanoyl, C1-5 alkoxycarbonyl, aryloxycarbonyl, benzyloxycarbonyl, C1-5 alkanoylamino, aroylamino, C1-5 alkylthio, arylthio C1-5 alkylsulfonylamino, arylsulfonylamino, C1-5 alkylaminosulfonyl, arylaminosulfonyl, C3-6 cycloalkyl and benzyloxy each of the aforementioned are optionally halogenated, halogen, hydroxy, oxo, carboxy, nitrile, nitro or NH m is 0, 1 or 2; and X is ═O, ═S or ═N—R or the pharmaceutically acceptable acceptable salts, esters, tautomers, individual isomers and mixtures of isomers thereof.