Patent ID: 6538141
Filing Date: 2003-03-25
Classification: C07C,C07D

Abstract:
A process for preparing a secondary amine N-oxide radicals (nitroxide radicals) from the corresponding secondary amine, comprising:a/ dissolving the secondary amine with a water-immiscible organic solvent, and then adding water to form a two-phase medium having an organic phase and an aqueous phase, b/ adding simultaneously with vigorous stirring an amount of aliphatic peracid in a peracid/secondary amine molar ratio ranging from 1.5 to 2.5, and an amount of an aqueous basic solution sufficient to give the aqueous phase of the two-phase medium a pH reading from 4 to 12, at a temperature of between âˆ’10Â° C. and +40Â° C., until conversion of the secondary amine is complete, and then c/ recovering the organic phase by separation of the phases by settling, and isolating the nitroxide by evaporating the organic solvent under reduced pressure.