Patent ID: 7557107
Filing Date: 2009-07-07
Classification: A61P,C07D

Abstract:
1. A compound of the formula: and the pharmaceutically acceptable salts thereof, wherein: R R R R H, R R R R R  wherein R R (8) heterocycloalkyl of the formula:  wherein R (9) —NH 2 provided that only one of R 21 , R 22 , and R 46 group can be —NH 2 and provided that when one of R 21 , R 22 , and R 46 is —NH 2 then the remaining groups are not —OH, (10) —OH provided that only one of R 21 , R 22 , and R 46 group can be —OH and provided that when one of R 21 , R 22 , and R 46 is —OH then the remaining groups are not —NH 2 , and (11) alkyl substituted with one or more substituents selected from the group consisting of: —OH and —NH 2 and provided that there is only one —OH or one —NH 2 group on a substituted carbon, or R and R