Patent ID: 8686117
Filing Date: 2014-04-01
Classification: C07K,Y10T

Abstract:
1. A method of inducing platelet aggregation, comprising adding, in a solution form, to blood or platelet-rich plasma, an un-crosslinked polypeptide having a peptide fragment (component A) represented by formula (1): where n represents an integer of from 20 to 5,000, and wherein the peptide of formula (1) is selected from the group consisting of: (Pro-Pro-Gly)- (Component B) and -(Pro-Hyp-Gly)- (Component C), wherein the molar ratio of the Component B:Component C in said peptide fragment is 10/90 to 0/100, and wherein said un-crosslinked polypeptide is capable of inducing said platelet aggregation even in the presence of an inhibitory amount of aspirin, as compared to collagen.