Patent ID: 6165942
Filing Date: 2000-12-26
Classification: C07F

Abstract:
A compound having the formula (I) or a salt thereof: ##STR276## wherein: Rf represents (C.sub.1 -C.sub.4)haloalkyl;X.about.Y represents:N.dbd.N,C(Ra).dbd.C(Rb), wherein Ra and Rb each independently represents hydrogen, halogen, (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy, (C.sub.1 -C.sub.4)haloalkyl, hydroxy, amino, mercapto, carboxyl, hydroxymethyl, carbamoyl, formyl, (C.sub.1 -C.sub.4)alkylcarbonyl, (C.sub.1 -C.sub.4)alkoxycarbonyl, (C.sub.1 -C.sub.4)alkylamino, (C.sub.2 -C.sub.6)alkenyl, (C.sub.2 -C.sub.6)alkynyl, (C.sub.1 -C.sub.4)alkymercapto, (C.sub.3 -C.sub.6)alkenylamino, (C.sub.3 -C.sub.6)alkynylamino, benzyloxy, benzylamino, (C.sub.1 -C.sub.4)alkylsulfinyl, (C.sub.1 -C.sub.4)alkylsulfonyl or pyridyl or phenyl, which is optionally substituted with halogen, (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy, (C.sub.1 -C.sub.4)haloalkyl, (C.sub.1 -C.sub.4)haloalkoxy or phenyl,C(Ra).dbd.N, wherein Ra is as defined above,N.dbd.C(Ra), wherein Ra is as defined above,CH(Ra)CH(Rb), wherein Ra and Rb are each as defined above, orCH.sub.2 CH.sub.2 CH.sub.2, CH.dbd.CHCH.sub.2 or CH.sub.2 CH.dbd.CH, orNHC(Ra)Rb, wherein Ra and Rb are each as defined above,C(Ra)(Rb)NH, wherein Ra and Rb are each as defined above, orC(.dbd.O)C(.dbd.O), CH.sub.2 C(.dbd.O)NH or CH.sub.2 CH.sub.2 SO.sub.2, orC(.dbd.O)CH(Ra), wherein Ra is as defined above,CH(Ra)C(.dbd.O), wherein Ra is as defined above, orC(.dbd.O)NH, C(.dbd.S)NH, NHC(.dbd.O) or NHC(.dbd.S), orC(.dbd.O)C(Ra).dbd.N, wherein Ra is as defined above,C(.dbd.O)C(Ra).dbd.C(Rb), wherein Ra and Rb are each as defined above,C(Ra).dbd.C(Rb)C(.dbd.O), wherein Ra and Rb are each as defined above,N.dbd.C(Ra)C(.dbd.O), wherein Ra is as defined above,CH(Ra)C(.dbd.O)NH, wherein Ra is as defined above,C(.dbd.O)N(Ra)C(.dbd.O), wherein Ra is as defined above,C(Ra).dbd.NC(.dbd.O), wherein Ra is as defined above,C(Ra)O, wherein Ra is as defined above, orC(.dbd.O)O, OC(.dbd.O) or SC(.dbd.O);A represents nitrogen or CH;Z represents:oxygen or sulfur,NRc, wherein Rc is hydrogen, (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxycarbonyl or (C.sub.1 -C.sub.4)alkoxycarbonylmethyl group, or phenyl which is optionally substituted with halogen, (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy or (C.sub.1 -C.sub.4)haloalkyl, orNNHRc, wherein Rc is as defined above;Rg represents hydrogen, halogen, cyano, (C.sub.1 -C.sub.6)alkoxycarbonyl, (C.sub.3 -C.sub.6)alkenyl, (C.sub.3 -C.sub.6)alkynyl or (C.sub.1 -C.sub.4)alkyl;R1, R2, R3, R4 and R5 each independently represents:hydrogen, halogen, nitro, cyano, thiocarbamoyl, carbamoyl, mercapto, hydroxyl, amino, formyl, carboxyl, vinyl, ethynyl, trimethylsilylethynyl, cyanomethyl, sulfamoyl, (C.sub.1 -C.sub.8)alkyl, (C.sub.3 -C.sub.8)alkenyl, (C.sub.1 -C.sub.4)alkylsulfonyl, (C.sub.3 -C.sub.8)alkynyl, (C.sub.3 -C.sub.8)cycloalkyl, (C.sub.1 -C.sub.4)haloalkyl, (C.sub.3 -C.sub.8)haloalkenyl, (C.sub.3 -C.sub.8)haloalkynyl, (C.sub.1 -C.sub.4)acyl, (C.sub.1 -C.sub.4)alkoxy(C.sub.1 -C.sub.2)alkyl or (C.sub.1 -C.sub.4)alkylsulfinyl, orphenyl which is optionally substituted with halogen, (C.sub.1 -C.sub.4)haloalkyl, (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy, (C.sub.1 -C.sub.4)haloalkoxy, methanesulfonyl, (C.sub.1 -C.sub.4)alkoxycarbonyl, nitro, hydroxyl, amino or cyano, or a group --O--CH(CH.sub.3)COR.sub.1 -C.sub.4)alkyl or --O--CH.sub.2 COR.sub.1 -C.sub.4)alkyl,a group --Q-(optionally substituted phenyl group), wherein Q is a saturated or unsaturated (C.sub.1 -C.sub.6)alkylene chain which is optionally branched and substituted with a halogen atom, and the optionally substituted phenyl group is as defined above,a group --O--Q-(optionally substituted phenyl group), wherein Q and the optionally substituted phenyl group are each as defined above,a group --S--Q-(optionally substituted phenyl group), wherein Q and the optionally substituted phenyl group are each as defined above,a group --NH--Q-(optionally substituted phenyl group), wherein Q and the optionally substituted phenyl group are each as defined above,a group --O-(optionally substituted phenyl group), wherein the optionally substituted phenyl group is as defined above,a group --S-(optionally substituted phenyl group), wherein the optionally substituted phenyl group is as defined above,a group --NH-(optionally substituted phenyl group), wherein the optionally substituted phenyl group is as defined above,--O--R11, wherein R11 represents (C.sub.1 -C.sub.8)alkyl, (C.sub.3 -C.sub.8)cycloalkyl, (C.sub.3 -C.sub.8)cycloalkyl(C.sub.1 -C.sub.4)alkyl, (C.sub.3 -C.sub.8)alkenyl, (C.sub.3 -C.sub.8)alkynyl, (C.sub.3 -C.sub.8)haloalkenyl, (C.sub.1 -C.sub.4)haloalkylcarbonyl, (C.sub.3 -C.sub.8)haloalkynyl, (C.sub.1 -C.sub.4)haloalkyl, (C.sub.1 -C.sub.4)alkoxy(C.sub.1 -C.sub.4)alkyl, cyanomethyl or (C.sub.1 -C.sub.4)acyl,--NH--R11, wherein R11 is as defined above,--S--R11, wherein R11 is as defined above, ora group --CON[(C.sub.1 -C.sub.4)alkyl].sub.2 or --CONH[(C.sub.1 -C.sub.4)alkyl], or--CO.sub.2 R12, wherein R12 represents (C.sub.1 -C.sub.8)alkyl, (C.sub.3 -C.sub.8)cycloalkyl, (C.sub.3 -C.sub.8)alkenyl or (C.sub.3 -C.sub.8)alkynyl, or optionally substituted phenyl, wherein the optionally substituted phenyl is as defined above, or a group --Q-(optionally substituted phenyl group), wherein Q and the optionally substituted phenyl group are each as defined above, or oxetan-3-yl, (C.sub.1 -C.sub.4)alkoxycarbonylmethyl or [(C.sub.1 -C.sub.4)alkyl].sub.2 amino group,--CONHR12, wherein R12 is as defined above,--Q--CO.sub.2 R12, wherein Q and R12 are each as defined above,--O--Q--CO.sub.2 R12, wherein Q and R12 are each as defined above,--NH--Q--CO.sub.2 R12, wherein Q and R12 are each as defined above,--S--Q--CO.sub.2 R12, wherein Q and R12 are each as defined above,--NHSO.sub.2 R13, wherein R13 represents (C.sub.1 -C.sub.8)alkyl, (C.sub.1 -C.sub.4)haloalkyl, (C.sub.3 -C.sub.6)cycloalkyl, (C.sub.3 -C.sub.8)alkenyl, (C.sub.3 -C.sub.8)alkynyl, benzyl or phenyl,--N(SO.sub.2 R13).sub.2, wherein R13 is as defined above,--CONHSO.sub.2 R14, wherein R14 is (C.sub.1 -C.sub.4)alkyl or (C.sub.1 -C.sub.4)haloalkyl,--N(R15)SO.sub.2 R13, wherein R13 is as defined above and R15 represents a (C.sub.1 -C.sub.6)alkyl, (C.sub.3 -C.sub.8)alkenyl, (C.sub.3 -C.sub.8)alkynyl, (C.sub.1 -C.sub.4)haloalkyl, (C.sub.3 -C.sub.8)haloalkenyl, (C.sub.3 -C.sub.8)haloalkynyl, (C.sub.1 -C.sub.6)acyl, fornyl, cyano (C.sub.1 -C.sub.4)alkyl,(C.sub.1 -C.sub.4)alkoxy(C.sub.1 -C.sub.4)alkyl or (C.sub.1 -C.sub.4)alkoxycarbonyl, or a group --C(.dbd.O)(optionally substituted phenyl group), wherein the optionally substituted phenyl group is as defined above,--NHCO.sub.2 R16, wherein R16 represents (C.sub.1 -C.sub.6)alkyl, (C.sub.3 -C.sub.8)alkenyl, (C.sub.3 -C.sub.8)alkynyl, (C.sub.1 -C.sub.4)haloalkyl or phenyl, or a group --Q-(optionally substituted phenyl group), wherein Q and the optionally substituted phenyl group are each as defined above,--O--CO.sub.2 R16, wherein R16 is as defined above,--N(R15)CO.sub.2 R16, wherein R15 and R16 are each as defined above,--N(R15)R11, wherein R11 and R15 are each as defined above, or2.