Patent ID: 6534541
Filing Date: 2003-03-18
Classification: A61K,A61P

Abstract:
A method of decreasing intraocular pressure in a subject in need of such treatment comprising:repeatedly topically administering to the eye of a subject in need of treatment an amount effective to decrease intraocular pressure in said eye of said subject of a compound with the formula â€ƒwherein R1 is hydrogen, lower alkyl, cyclohexyl, allyl, or benzyl; R2 is hydrogen, methyl, ethyl, or propyl; or wherein R1 and R2 together with the nitrogen to which they are attached form a morpholino or piperidino radical; R3 is hydrogen or lower alkyl; R4 and R5 are, independently, lower alkyl; â€ƒwherein the â€ƒgroup is in the meta, ortho, or para position relative to the carbamate group; or a pharmaceutically acceptable acid addition salt thereof.