Patent ID: 7541020
Filing Date: 2009-06-02
Classification: C07H

Abstract:
1. A composition comprising (a) a compound having the formula: wherein X is selected from the group consisting of O and S at the axial or equatorial position; Y is selected from the group consisting of O and NH; n, m, p and q are integers from 0 to 6: R 1 , R 2 and R 3 are the same or different and are fatty acyl residues having from 1 to about 20 carbon atoms and where one of R 1 , R 2 and R 3 is optionally hydrogen; R 4 and R 5 are the same or different and are selected from the group consisting of H and methyl; R 6 and R 7 are the same or different and are selected from the group consisting of H, hydroxy, alkoxy, phosphono, phosphonoxy, sulfo, sulfooxy, amino, mercapto, cyano, nitro, formyl and carboxy, and esters and amides thereof; and R 8 and R 9 are the same or different and are selected from the group consisting of phosphono and H, and at least one of R 8 and R 9 is a phosphono or a pharmaceutically acceptable salt thereof; and (b) one or more polypeptides.