Patent ID: 8067186
Filing Date: 2011-11-29
Classification: A61K,A61P,C07K,G01N

Abstract:
1. A method of identifying a competing antibody selected from the group consisting of: (i) an antibody that specifically binds to the same epitope on a cell expressing a CA6 antigen that is bound by a monoclonal antibody produced by the hybridoma cell line DS6 deposited with the American Type Culture Collection as deposit number PTA-4449 or the same epitope on a CA6 antigen that is bound by a monoclonal antibody produced by the hybridoma cell line DS6 deposited with the American Type Culture Collection as deposit number PTA-4449, and (ii) an antigen-binding fragment of the antibody of (i) that specifically binds to the same epitope on a cell expressing a CA6 antigen that is bound by a monoclonal antibody produced by the hybridoma cell line DS6 deposited with the American Type Culture Collection as deposit number PTA-4449 or the same epitope on a CA6 antigen that is bound by a monoclonal antibody produced by the hybridoma cell line DS6 deposited with the American Type Culture Collection as deposit number PTA-4449, the method comprising: