Patent ID: 8580925
Filing Date: 2013-11-12
Classification: C07K,G01N

Abstract:
1. An examination reagent for carcinomas and adenomas, except colorectal carcinomas and colorectal adenomas, comprising, as a major component, an antibody binding specifically with an antigen carrying sugar residues, which is present in cells expressing HEC-GlcNAc6ST gene and is absent or almost absent in cells expressing GlcNAc6ST-1 or I-GlcNAc6ST gene, wherein “GlcNAc6ST” refers to a family of GlcNAc-6-O-sulfotransferases, and wherein the sugar residues comprise a -Gal β1-3/4(SO 3 -6)GlcNAc β1- region where the specific binding occurs.