Patent ID: 6815184
Filing Date: 2004-11-09
Classification: C07K,C12N

Abstract:
A method of producing biologically active &agr;-2b-interferon in a duckweed plant culture or a duckweed nodule culture, comprising the steps of:(a) culturing within a duckweed culture medium a duckweed plant culture or a duckweed nodule culture, wherein said duckweed plant culture or said duckweed nodule culture is stably transformed to express said biologically active &agr;-2b-interferon, and wherein said biologically active &agr;-2b-interferon is expressed from a nucleotide sequence comprising a coding sequence for the polypeptide and an operably linked coding sequence for a signal peptide that directs secretion of the &agr;-2b-interferon into the culture medium; and (b) collecting said biologically active &agr;-2b interferon from the duckweed culture medium.