Patent ID: 8735611
Filing Date: 2014-05-27
Classification: A61K,A61P,C07D

Abstract:
1. A crystalline form of cabazitaxel selected from the ethyl acetate solvate, the tetrahydrofuran solvate, the methyl ethyl ketone solvate, the diethyl ketone solvate, the diethyl carbonate solvate, or the dimethyl sulfoxide solvate, wherein said crystalline form is substantially free of other crystalline forms; and the ethyl acetate solvate is characterized by an XRPD pattern that comprises peaks at 7.9, 8.6, and 10.1 (+0.1 degrees 2θ); the tetrahydrofuran solvate is characterized by an XRPD pattern that comprises peaks at 7.8, 8.9, and 10.2 (±0.1 degrees 2θ); the methyl ethyl ketone solvate is characterized by an XRPD pattern that comprises peaks at 7.8, 8.8, and 10.1 (±0.1 degrees 2θ); the diethyl ketone solvate is characterized by an XRPD pattern that comprises peaks at 7.8, 8.8, and 10.1 (±0.1 degrees 2θ); the diethyl carbonate solvate is characterized by an XRPD pattern that comprises peaks at 7.8, 8.6, and 10.1 (±0.1 degrees 2θ); and the dimethyl sulfoxide solvate is characterized by an XRPD pattern that comprises peaks at 7.2, 7.6, and 8.2 (±0.1 degrees 2θ).