Patent ID: 7456290
Filing Date: 2008-11-25
Classification: C07D

Abstract:
1. A process for the preparation of a 2-aminomethylpyridine derivative of general formula (I) wherein n represents 0, 1, 2 or 3, X is a halogen atom, each Y, which may be the same or different, is selected from the group consisting of a halogen atom, halogenoalkyl, alkoxycarbonyl, and alkylsulphonyl, or a salt thereof; comprising hydrogenating a 2-cyanopyridine derivative of general formula (II): in which n, X, and Y are as described above, in acetic acid using Raney nickel, at a temperature of from 30° C. to 70° C., under a hydrogen pressure of from 10 to 20 bar.