Patent ID: 6822078
Filing Date: 2004-11-23
Classification: C07K,G01N,Y10S

Abstract:
A kit for diagnosing an autoimmune disease, the kit comprising:a first antigen selected from the group consisting of a polypeptide having amino acid sequence indicated by SEQ ID NO:1, SEQ ID NO:4, SEQ ID NO:5, or a fragment of said polypeptide, wherein said polypeptide or fragment thereof specifically binds with an antibody from an autoimmune disease patient; a second antigen selected from the group consisting of a polypeptide having an amino acid sequence indicated by SEQ ID NO:2, SEQ ID NO:6, SEQ ID NO:8, or a fragment of said polypeptide, wherein said polypeptide or fragment thereof specifically binds with an antibody from an autoimmune disease patient; a first component for detecting a first antigen-antibody complex; and a second component for detecting a second antigen-antibody complex; wherein the autoimmune disease is selected from the group consisting of rheumatoid arthritis, human systemic lupus erythematosus. SjÃ¶gren's syndrome, BehÃ§et's disease, primary biliary cirrhosis, microscopic polyangitis/polyarteritis nodosa, ulcerative colitis, Crohn's disease and autoimmune hepatitis.