Patent ID: 6265633
Filing Date: 2001-07-24
Classification: C12N

Abstract:
An isolated and purified nucleic acid encoding a gene specifically expressed in hop lupulin glands, said nucleic acid selected from the group consisting of:(a) a nucleic acid comprising the nucleotide sequence of SEQ ID NO: 2;(b) a nucleic acid comprising a nucleic acid sequence which hybridizes to the nucleic acid of (a), wherein the hybridization conditions are at least as stringent as the following: hybridization in 5.times.SSC at 42.degree. C. followed by washing once in 2.times.SSC at 56.degree. C. and then washing twice in 0.1.times.SSC at 68.degree. C.; wherein said nucleic acid sequence encodes a protein with the biological activity of a chalcone synthetase and a valerophenone synthetase;(c) a nucleic acid encoding the amino acid sequence of SEQ ID NO: 1;(d) a nucleic acid comprising a nucleic acid sequence which hybridizes to a nucleic acid of (c), wherein the hybridization conditions are at least as stringent as the following: hybridization in 5.times.SSC at 42.degree. C. followed by washing once in 2.times.SSC at 56.degree. C. and then washing twice in 0.1.times.SSC at 68.degree. C.; wherein said nucleic acid sequence encodes a protein with the biological activity of a chalcone synthetase and a valerophenone synthetase; and(e) a nucleic acid that is complementary to (a), (b), (c), or (d).