Patent ID: 6054474
Filing Date: 2000-04-25
Classification: A61P,C07C,C07D

Abstract:
A compound of formula (I): ##STR16## wherein R.sub.1 is H, C.sub.1-6 alkyl, or C.sub.6-12 aryl optionally substituted with polar groups;R.sub.2 and R.sub.3 are independently H, OH, C.sub.1-6 alkyl, --C(NH)--NH.sub.2, a positively charged group, or C.sub.7-13 aralkyl optionally substituted with NH.sub.2, OH, C.sub.1-6 alkyl, or halogen; orR.sub.2 and R.sub.3 together form a 5 to 6 member ring optionally incorporating a heteroatom;R.sub.4 is H, C.sub.1-6 alkyl, OR.sub.6, SR.sub.6 or N(R.sub.6).sub.2, wherein each R.sub.6 is independently H, C.sub.1-3 alkyl;X is S, SO, or SO.sub.2 ;n is an integer from 0 to 2;m is an integer from 1 to 3.