Patent ID: 7221785
Filing Date: 2007-05-22
Classification: G06K,G06T

Abstract:
1. A method for determining a background signal intensity for a particular feature from a representation of scanned intensity values of a molecular array comprising data points and containing discrete features at specified locations, each feature having a region of interest containing a number of data points, the method comprising: specifying a size for a background region corresponding to the feature; selecting as background data points those data points within the specified background region; filtering the selected data points to remove all data points that lie within specified locations of features and at least one region of interest of features in the region of specified size for the background region; and determining the background signal intensity for the particular feature from the filtered, selected data points, wherein background-subtraction of data points from the particular feature using the determined background signal intensity facilitates calculation of accurate and reproducible log ratios between at least one of multi-channel and inter-array data.