Patent ID: 9126934
Filing Date: 2015-09-08
Classification: C07D

Abstract:
1. A process for producing a 4-carbonyloxyquinoline derivative represented by general formula (1): wherein reacting a quinolone derivative represented by general formula (2): wherein R wherein R or an acid anhydride represented by general formula (4): wherein R in the presence of a phase transfer catalyst and a base, wherein the phase transfer catalyst is tetrabutylammonium bromide wherein the base is an aqueous hydroxide solution of an alkali metal or an alkaline earth metal or an aqueous carboxide solution of an alkali metal or an alkaline earth metal, and the base has a concentration of 40% or more by weight, wherein the solvent is a mixed solvent comprising amides and one solvent selected from the group consisting of aromatic hydrocarbons, halogenated aromatic hydrocarbons, halogenated aliphatic hydrocarbons, aliphatic hydrocarbons, ethers and ketones.