Patent ID: 7883711
Filing Date: 2011-02-08
Classification: A01N,A61K,A61L,A61P,C11D

Abstract:
1. A method of killing and/or inhibiting growth of gram-positive bacterial cells comprising contacting the microbial cells with an antimicrobial polypeptide selected from the group consisting of: (a) a polypeptide with an amino acid sequence which has a degree of sequence identity to amino acids 1-85 of SEQ ID NO: 2 of at least 95%; (b) a polypeptide which is encoded by a nucleic acid sequence which hybridizes under medium stringency conditions with wherein the medium stringency conditions comprise prehybridization and hybridization at 42° C. in 5×SSPE, 0.3% SDS, 200 micrograms/ml sheared and denatured salmon sperm DNA, and 35% formamide, following by washing three times each for 15 minutes using 2×SSC, 0.2% SDS at 55° C.; and (c) a fragment of the sequence of amino acids 1-85 of SEQ ID NO: 2, which has antimicrobial activity.