Patent ID: 6387944
Filing Date: 2002-05-14
Classification: A61K,A61P,C07D,C07K,C08G,Y02P

Abstract:
A compound of the formula I in whichR1 is methyl, ethyl, propyl, butyl; R2 is H, OH, NH2, NHâ€”(C1-C6)-alkyl; R3 is an amino acid radical, diamino acid radical, triamino acid radical, tetraamino acid radical, the amino acid radical, diamino acid radical, triamino acid radical or tetraamino acid radical optionally being mono- or polysubstituted by an amino acid protective group; R4 is methyl, ethyl, propyl, butyl; R5 is methyl, ethyl, propyl, butyl; Z is â€”(C&boxH;O)nâ€”C0-C16-alkyl, â€”(C&boxH;O)nâ€”C0-C16-alkyl-NHâ€”, â€”(C&boxH;O)nâ€”C0-C16-alkyl-Oâ€”, â€”(C&boxH;O)nâ€”C1-C16-alkyl-(C&boxH;O)m, a covalent bond; n is 0 or 1; m is 0 or 1; or its pharmaceutically tolerable salts and physiologically functional derivatives.