Patent ID: 8992915
Filing Date: 2015-03-31
Classification: A61K,A61P,C07K

Abstract:
1. A method for the treatment of a patient suffering from chronic lymphocytic leukemia (CLL) or B-cell non-Hodgkin's lymphoma (B-NHL), the method comprising administering to the patient (a) a CD37 antibody and (b) a combination chemotherapy regimen comprising ICE (ifosfamide, carboplatin, and etoposide (or etoposide phosphate)), whereby the CD37 antibody comprises: a) a variable heavy chain comprising CDRs having the SEQ ID NOs: 15, 16 or 21, and 17, and b) a variable light chain comprising CDRs having the SEQ ID NOs: 18, 19 and 20.