Patent ID: 7205139
Filing Date: 2007-04-17
Classification: A61K,A61P,C07K,C12N,Y10S

Abstract:
1. An isolated nucleic acid molecule comprising a polynucleotide selected from the group consisting of: (a) a nucleotide sequence encoding the t-PALP polypeptide having the amino acid sequence at positions −21 to 242 of SEQ ID NO:2; (b) a nucleotide sequence encoding the t-PALP polypeptide having the amino acid sequence at positions −20 to 242 of SEQ ID NO:2; (c) a nucleotide sequence encoding the mature t-PALP polypeptide having the amino acid sequence at positions 1 to 242 in SEQ ID NO:2; (d) a nucleotide sequence encoding the protease domain of the t-PALP polypeptide having the amino acid sequence at positions 64 to 242 in SEQ ID NO:2; (e) a nucleotide sequence encoding the complete amino acid sequence encoded by the cDNA clone contained in ATCC Deposit No. 209023; (f) a nucleotide sequence encoding the complete amino acid sequence excepting the N-terminal methionine encoded by the cDNA clone contained in ATCC Deposit No. 209023; (g) a nucleotide sequence encoding the mature t-PALP polypeptide encoded by the cDNA clone contained in the ATCC Deposit No. 209023; (h) a nucleotide sequence encoding the protease domain of the t-PALP polypeptide encoded by the cDNA clone contained in the ATCC Deposit No. 209023; and (i) a nucleotide sequence completely complementary to any of the complete nucleotide sequences in (a), (b), (c), (d), (e), (f), (g), or (h) above.