Patent ID: 8277762
Filing Date: 2012-10-02
Classification: B01L,G01N,Y10T

Abstract:
1. An apparatus for assaying effects of test formulations on barrier properties of at least one piece of skin, comprising: a first plate including a generally cylindrical rod mounted in the plate channel of the first plate and extending lengthwise along a longitudinal axis, the rod including a plurality of rod channels that are generally perpendicular to the longitudinal axis, wherein each of the rod channels is configured to be in general alignment with a respective one of the first wells in the row, wherein the rod is rotatable about the longitudinal axis between an open position in which the rod channels allow the first plurality of formulations to be introduced or removed through the openings of the first wells in the row, and a closed position in which the rod retains the first plurality of formulations in the first wells and promotes contact between the first plurality of formulations in the first wells and the at least one piece of skin independently of an orientation of the apparatus; and a second plate configured for assembly with the first plate so that the at least one piece of skin may be sandwiched between the first and second plates, the second plate including