Patent ID: 7105303
Filing Date: 2006-09-12
Classification: A61K,A61P,C07K,C12N,Y10S

Abstract:
1. An assay kit for detecting the presence of a hepatitis C virus (HCV) glycoprotein having mannose-terminated glycosylation, wherein less than about 10% of the total N-linked carbohydrate on said HCV glycoprotein is sialic acid, wherein said HCV glycoprotein is selected from the group consisting of a glycoprotein expressed from the E1 region of HCV, a glycoprotein expressed from the E2 region of HCV, and aggregates thereof, said kit comprising: a solid support; a mannose binding protein that binds said HCV glycoprotein; and an isolated antibody reactive with said HCV glycoprotein; wherein one of said antibody and said mannose binding protein is bound to said solid support.