Patent ID: 8691814
Filing Date: 2014-04-08
Classification: A61K,A61P,C07D

Abstract:
1. A method for inhibiting E-selectin and I-CAM1, wherein a disease treatable by such inhibition is cancer, comprising: administering to a subject in need thereof a therapeutically effective amount of a compound having the structure (I): or a pharmaceutically acceptable salt, ester or salt of such ester thereof; wherein n is an integer from 0-4; R R each occurrence of R whereby each of the foregoing aliphatic or heteroaliphatic moieties may be independently substituted or unsubstituted, cyclic or acyclic, linear or branched, saturated or unsaturated and wherein each of the foregoing aryl or heteroaryl moieties may be independently substituted or unsubstituted; and a pharmaceutically acceptable carrier or diluent; and optionally further comprising administering an additional therapeutic agent.