Patent ID: 6204277
Filing Date: 2001-03-20
Classification: A61P,C07D

Abstract:
A novel propionic acid derivative of the formula (I): ##STR87##wherein R is a group of the formula: ##STR88##whereinR' is an optionally substituted aromatic hydrocarbon, an optionally substituted alicyclic hydrocarbon, an optionally substituted heterocyclic group or an optionally substituted fused heterocyclic group, andR.sub.5 is a lower alkyl;R.sub.4 is a hydrogen atom or a lower alkyl;R.sub.6 is a hydrogen atom;R.sub.7 is carboxy, an acyl, an optionally substituted alkoxycarbonyl, an optionally substituted lower alkyl, an optionally substituted carbamoyl, an optionally substituted aryloxycarbonyl, or an optionally substituted aralkyloxycarbonyl;R.sub.9 is a hydrogen atom, an optionally substituted lower alkyl or an optionally substituted alkoxycarbonyl; andR.sub.10 is a hydroxy, an optionally substituted amino, an optionally substituted lower alkoxy, an optionally substituted lower alkyl, an optionally substituted aryloxy, or an optionally substituted aralkyloxy;provided that when R.sub.7 is an alkoxycarbonyl and R.sub.9 is a hydrogen atom, R.sub.10 is not a lower alkoxy,or a pharmaceutically acceptable salt thereof.