Patent ID: 6994966
Filing Date: 2006-02-07
Classification: C07B,C07H,C07K,C40B,G01N

Abstract:
1. A method of identifying a carbohydrate capable of binding an entity, the method comprising the steps of: (a) enzymatically synthesizing an addressable carbohydrate library including a plurality of carbohydrate structures each being attached at a specific and addressable location of an array, wherein each of said plurality of carbohydrate structures is composed of naturally occurring monosaccharides, such that a stereo-specificity of each bond interconnecting said monosaccharide units of said plurality of carbohydrate structures is defined by said addressable location thereof on said array and wherein each of said plurality of carbohydrate structures is composed of at least 2 and no more than 20 monosaccharide units each being naturally occurring; wherein each of said plurality of carbohydrate structures is attached to said array via a linker, said linker including at least one ethylenglycol derivative, at least two cyanuric chloride derivatives and an anilino group and (b) screening said addressable carbohydrate library with the entity thereby identifying the carbohydrate capable of binding the entity.