Patent ID: 6548491
Filing Date: 2003-04-15
Classification: A61K,C07J

Abstract:
A 17-desoxy-1,3,5(10)-estratriene containing the molecular moiety at the C-17 position of the estratriene nucleus, wherein:j is an integer in the range of 0 to 5 inclusive; p is an integer in the range of 0 to 6; R29 and R30 are selected from the group consisting of hydrogen, lower alkyl, and halogenated lower alkyl, or are linked together to form a heterocycloalkyl ring, with the proviso that R29 and R30 are not both hydrogen; and L is a five- or six-membered cyclic moiety that may or may not be aromatic, optionally containing 1 to 4 heteroatoms selected from the group consisting of N, O and S and combinations thereof, and optionally substituted with one or more substituents selected from the group consisting of alkyl, alkenyl, alkoxy, halogenated alkyl, alkenyl, and alkoxy, carboxyl, hydroxy, amino, nitro, cyano, and halogen.