Patent ID: 7320887
Filing Date: 2008-01-22
Classification: C11D,C12N

Abstract:
1. A modified alkaline protease comprising: a substitution of a threonine for the residue at the position corresponding to position 3 of the mature protease of SEQ ID NO:2; a substitution of an isoleucine for the residue at the position corresponding to position 4 of the mature protease of SEQ ID NO:2; a substitution of an alanine, a threonine, or an arginine for the residue at the position corresponding to position 61 of the mature protease of SEQ ID NO:2; and a substitution of an isoleucine for the residue at the position corresponding to position 199 of the mature protease of SEQ ID NO:2, wherein the modified alkaline protease is a mature protease comprising the gaps in amino acid sequence relative to the amino acid sequences of subtilisin BPN' and subtilisin Carlsberg depicted in