Patent ID: 8846674
Filing Date: 2014-09-30
Classification: A61P,C07D

Abstract:
1. A method for treating glaucoma, elevated ocular pressure or ocular hypertension in a patient in need thereof comprising administering to the patient an effective amount of a composition comprising a pharmaceutically acceptable carrier and a nitric oxide enhancing arbaprostil compound of Formula (II), a nitric oxide enhancing alprostadil or PGE 1 compound of Formula (III), a nitric oxide enhancing bimatoprost compound of Formula (IV), a nitric oxide enhancing carboprost compound of Formula (V), a nitric oxide enhancing cloprostenol compound of Formula (VI), a nitric oxide enhancing dimoxaprost compound of Formula (VII), a nitric oxide enhancing dinoprost compound of Formula (VIII), a nitric oxide enhancing enprostil compound of Formula (IX), a nitric oxide enhancing enisoprost compound of Formula (X), a nitric oxide enhancing fenprostalene compound of Formula (XI), a nitric oxide enhancing froxiprost compound of Formula (XII), a nitric oxide enhancing gemeprost compound of Formula (XIII), a nitric oxide enhancing latanoprost compound of Formula (XIV), a nitric oxide enhancing meteneprost compound of Formula (XV), a nitric oxide enhancing mexiprostil compound of Formula (XVI), a nitric oxide enhancing misoprostol compound of Formula (XVII), a nitric oxide enhancing misoprostol acid compound of Formula (XVIII), a nitric oxide enhancing nocloprost compound of Formula (XIX), a nitric oxide enhancing ONO 373 compound of Formula (XX), a nitric oxide enhancing ornoprostil compound of Formula (XXI), a nitric oxide enhancing prostalene compound of Formula (XXII), a nitric oxide enhancing PGE 2 compound of Formula (XOH), a nitric oxide enhancing PGF 1 compound of Formula (XXIV), a nitric oxide enhancing PGF 2α compound of Formula (XXV), a nitric oxide enhancing rioprostil compound of Formula (XXVI), a nitric oxide enhancing rosaprostol compound of Formula (XXVII), a nitric oxide enhancing remiprostol compound of Formula (XXVIII), a nitric oxide enhancing sulprostone compound of Formula (XXIX), a nitric oxide enhancing tafluprost compound of Formula (XXX), a nitric oxide enhancing travoprost compound of Formula (XXXI), a nitric oxide enhancing trimoprostil compound of Formula (XXXII), a nitric oxide enhancing tiprostanide compound of Formula (XXXIII), a nitric oxide enhancing unoprostone compound of Formula (XXXIV), and pharmaceutically acceptable salts thereof; wherein the compound of Formula (II) is: wherein: wherein