Patent ID: 6596310
Filing Date: 2003-07-22
Classification: A61D,A61K,Y10S

Abstract:
A method for artificial insemination of a mammal comprising:(a) providing an admixture of capsules comprising a core containing sperm in a semen extender and a gel membrane formed of a gel forming polymer encapsulating the core, wherein the capsules have membranes of different thicknesses so that the capsules release the sperm in a mammal uterus at varying times during the fertile period of the mammal, said extender being free of glucose, xanthine oxidase, and H2O2, and comprising a carbohydrate source selected from the group consisting of fructose, fructose-6-phosphate, pyruvate, lactate, and mixtures thereof that provides an energy source for the sperm without facilitating capacitation of the sperm; and (b) introducing the admixture of capsules into the uterus of the mammal wherein the sperm in the capsules in the uterus is capacitated enabling the fertilization of an egg at the varying times during the fertile period of the mammal.