Patent ID: 6589525
Filing Date: 2003-07-08
Classification: A61C,A61L,A61P,C12M

Abstract:
A method of manufacturing a dental implant comprising:preparing an implant composed of a root portion and a crown portion and constituted by an inert biocompatible material in a shape which is adapted to an extracted tooth; immersing the root portion of said implant in a culture of undifferentiated mesenchymal cells with an apparatus comprising a culture dish (10) the shape of which comprises a longitudinal axis, said culture dish being closed by a cover (11) and containing a porous wall (20) delimiting a first space (21) containing the cell culture medium, and a second space (22) containing the cells being cultured, and in which the root portion of the implant is immersed, said wall having a configuration such that a gap 0.1 to 5 mm is left between the root portion of the implant and the wall, creating an artificial alveolus, the culture of mesenchymal undifferentiated cells as above-mentioned and in a culture medium the composition of which allows differentiation into cementoblasts and fibroblasts, over a period which is sufficient for said differentiation and for adhesion of cementoblasts to the root portion and the formation of a first layer of cementum and of an alveolodental ligament primordium attached to said cementum; recovering the implant carrying differentiated tissues affixed to its root portion.