Patent ID: 8039675
Filing Date: 2011-10-18
Classification: C07D,C07F

Abstract:
1. A chiral catalyst comprising the reaction product of a ruthenium compound, a chiral bis(phosphine) and a chiral diamine of formula (I) in which R 1 , R 2 , R 3 and R 4 are independently hydrogen, a saturated or unsaturated alkyl or cycloalkyl group, an aryl group or a urethane or sulphonyl group, R 1 and R 2 may be linked or R 3 and R 4 may be linked so as to form a 4 to 7-membered ring structure incorporating the nitrogen atom, at least one of R 1 , R 2 , R 3 and R 4 is hydrogen; A is a linking group consisting of one or two substituted or unsubstituted carbon atoms; R 5 , R 6 , R 7 and R 8 are independently hydrogen, a saturated or unsaturated alkyl or cycloalkyl group, or an aryl group, wherein one or more of R 5 , R 6 , R 7 and R 8 forms one or more ring structures with linking group A, and the chiral bis(phosphine) is selected from the group consisting of BINAP, DUPHOS, BIPHEP, TMBTP, BITIANAP, BIBFUP, bppm, CARBOPHOS, JOSIPHOS, BPE, DEGPHOS, DIOP, BIPNOR, PHANEPHOS, SELKE and BINAPAN.