Patent ID: 8754205
Filing Date: 2014-06-17
Classification: A61K,C07J

Abstract:
1. An extract obtained from fenugreek seeds by a commercially viable process comprising the steps of: providing plurality of fenugreek seeds and crushing the same by milling and grinding; performing a primary extraction on the prepared fenugreek seeds using a first hydrophilic polar solvent which is a lower primary aliphatic alcohol followed by ion-exchange chromatography; performing a secondary extraction after ion-exchange chromatography using a composite solvent which is a mixture of a chlorohydrocarbon and an aliphatic alcohol; and decolorizing the final extract by use of activated charcoal concentration of the extract by heating and vacuum drying sieving the final powdered product, wherein seeds used in the extraction process have a furostanolic saponin content of not less than 1%, the extraction process is carried out below 80 degree Celsius, and wherein the final extract comprises a mixture of five furostanolic saponins in which protodioscin is one of the marker compounds, as measured by HPLC.