Patent ID: 7445931
Filing Date: 2008-11-04
Classification: A61P,C12N

Abstract:
1. A method of producing a human neural cell comprising, a) providing a pluripotent human cell; and b) culturing the pluripotent human cell with a composition comprising a ceramide compound selected from the group consisting of N-(2-hydroxy-1-(hydroxymethyl)ethyl)-palmitoylamide (“S16”), N-(2-hydroxy-1-(hydroxymethyl)ethyl)-oleoylamide (“S18”), N,N-bis(2-hydroxyethyl)palmitoylamide (“B16”), N,N-bis(2-hydroxyethyl)oleoylamide (“B18”) N-tris(hydroxymethyl)methyl-palmitoylamide (“T16”), N-tris(hydroxymethyl)methyl-oleoylamide (“T18”), N-acetyl sphingosine (“C2-ceramide”), and N-hexanoylsphingosine (“C6-ceramide”) to produce the human neural cell.