Patent ID: 6255469
Filing Date: 2001-07-03
Classification: C12N

Abstract:
A periodic polynucleic acid structure, comprising a lattice of adjacent coplanar repeating units, each repeating unit comprising at least two antiparallel nucleic acid multi-crossover molecules, each of said at least two antiparallel nucleic acid multi-crossover molecules comprising two or more adjacent double helical domains, at least two of said two or more adjacent double helical domains having a first and second cohesive ends, each of said adjacent double helical domains having helix axes in parallel and being connected to adjacent double helical domains at two or more crossover sites, with each antiparallel nucleic acid multi-crossover molecules being connected to an adjacent antiparallel nucleic acid multi-crossover molecule by complementary cohesive ends, thereby forming an extended double helical domain between a first double helical domain of an antiparallel nucleic acid multi-crossover molecule and a second double helical domain of an adjacent antiparallel nucleic acid multi-crossover molecule, wherein a second double helical domain of said antiparallel nucleic acid multi-crossover molecule is not colinear and connectible with a first double helical domain of said adjacent antiparallel nucleic acid crossover molecule to form an extended double helical domain, and wherein each repeating unit is connected to an adjacent repeating unit in the same plane by complementary cohesive ends to form at least one extended double helical domain between adjacent repeating units in the same plane.