Patent ID: 8377869
Filing Date: 2013-02-19
Classification: A61K,A61M,A61P

Abstract:
1. A method for the treatment of hyperglycemia or diabetes in a patient, comprising the step of administering prandially to a patient in need of treatment an inhalable rapid-acting dry powder GLP-1 formulation, the dry powder formulation comprising microparticles comprising a therapeutically effective amount of a GLP-1 molecule in an amount of at least about 0.5% by weight and a diketopiperazine, wherein the weight ratio of diketopiperazine to GLP-1 is at least about 17:3, and a dipeptidyl peptidase-IV (DPP-IV) inhibitor, and wherein the GLP- 1 formulation comprises about 0.5 mg to about 3 mg of GLP-1 dose.