Patent ID: 6833488
Filing Date: 2004-12-21
Classification: A61L,C08B,C08G,C08H

Abstract:
A bio-compatible, biodegradable macromolecular water-absorbent polymeric material having a three-dimensional configuration with intermolecular covalent bonds and containing free functional groups selected from OH, SH, NH2, and COOH, said polymer being formed by polymer-polymer inter-coupling interaction between a natural water-soluble polymer A or its derivatives having a molecular weight between 20,000 and 500,000 Da, and a synthetic polymer B in a ratio of A:B of 15:85 to 85:15,wherein the natural polymer A is selected from the group consisting of: A1)â€”non-ionic natural, partially denatured or chemically modified polymer, that does not dissociate in water and which can undergo polymer-polymer intercoupling reactions, having only free hydroxyl groups in an amount of at least 5Ã—10âˆ’3 moles OH/g, and optionally containing non-ionic groups, A2)â€”anionic natural, partially denatured or chemically modified polymer, that dissociates in water to form anions and which can undergo polymer-polymer intercoupling reactions, said polymer optionally containing non-ionic groups, A3)â€”cationic natural, partially denatured or chemically modified polymer, that dissociates in water to form cations and which can undergo polymer-polymer intercoupling reactions, said polymers optionally containing non-ionic groups, A4)â€”amphoteric natural, partially denatured or chemically modified polymer, that dissociates in water to form both anions and cations and which can undergo polymer-polymer intercoupling reactions, and A5)â€”mixtures of A1-A4, polymer A being capable of undergoing polymer-polymer intercoupling, and wherein: the synthetic polymer B is a linear or branched reactive synthetic copolymer having a molecular weight of 10,000-500,000 Da derived from a vinyl monomer and an ethylenically unsaturated monomer, said copolymer having a backbone with polymeric subunits Rn and Rr wherein R represents a subunit covalently bonded to the polymer backbone, n represents non-reactive chemical functional groups and r represents reactive chemical functional groups.