Patent ID: 6197962
Filing Date: 2001-03-06
Classification: C07D

Abstract:
A method for producing a 2-sulfonylpyridine derivative represented by the formula (III) ##STR21##wherein R.sup.1 is a hydrogen atom or an alkyl group or an aryl group that may be substituted, R.sup.2 and R.sup.3 are a hydrogen atom, a halogen atom, or an alkyl group or an aryl group that may be substituted, R.sup.4 is a hydrogen atom, a halogen atom, an alkoxyl group, an alkylthio group, a cyano group, an acyloxy group, an alkoxycarbonyl group, a protected amino group that may be substituted, or an alkyl group or an aryl group that may be substituted, and together R.sup.2 and R.sup.3 or R.sup.3 and R.sup.4 can represent --(CH.sub.2).sub.n -- where n is 3 or 4, and R.sup.5 is an alkyl group, a cycloalkyl group, an aryl group, or an aralkyl group that may be substituted, which method comprises:reacting an .alpha., .beta.-unsaturated carbonyl compound represented by general formula (I) ##STR22##where R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are the same as previously definedwith a sulfonyl cyanide represented by general formula (II)R.sup.5 SO.sub.2 CN (II)where R.sup.5 is the same as previously definedto obtain the 2-sulfonylpyridine derivative represented by general formula (III).