Patent ID: 6391287
Filing Date: 2002-05-21
Classification: A61K,A61P,A61Q,Y10S

Abstract:
A composition, comprising:at least one lipophilic sunscreen; and at least one bicyclic aromatic compound represented by formula (I): whereinR1 represents a hydrogen atom, a radical â€”CH3, a radical â€”CH2â€”Oâ€”R3, a radical â€”CH2â€”Oâ€”COâ€”R4, a radical â€”Oâ€”R5, a radical â€”Oâ€”(CH2)mâ€”(CO)nâ€”R6, a radical â€”COâ€”R7, a radical â€”COâ€”Oâ€”R8 or a radical â€”S(O)pâ€”R9, R2 represents a hydrogen atom or a halogen atom, a lower alkyl radical, an â€”NO2 radical, a radical â€”Oâ€”COR4, a radical â€”OR9 or a radical Ar represents a radical selected from the group consisting of the radicals of formula (a), (b), (c), (d) and (e): X represents â€”Oâ€”, â€”S(O)tâ€” or a radical â€”NR9â€”, Y and Z represent â€”Oâ€”, â€”S(O)tâ€” or a radical â€”CR11R12, m is an integer equal to 1, 2 or 3, n is an integer equal to 0 or 1, p is an integer equal to 0, 1, 2 or 3, t is an integer equal to 0, 1 or 2, R3, R5, R9, R10, R11 and R12 represent, independently of each other, a hydrogen atom or a lower alkyl radical, R4 represents a lower alkyl radical, R6 represents a lower alkyl radical or a heterocycle, R7 represents a hydrogen atom, a lower alkyl radical or a radical: wherein Râ€² and Râ€³, which may be the same or different, represent a hydrogen atom, a lower alkyl radical, a mono- or polyhydroxyalkyl radical, an optionally substituted aryl radical or an amino acid or peptide or sugar residue, or, alternatively, taken together, form a heterocycle, R8 represents a hydrogen atom, a linear or branched alkyl radical containing from 1 to 20 carbon atoms, an alkenyl radical, a mono- or polyhydroxyalkyl radical, an optionally substituted aryl or aralkyl radical, a sugar residue or an amino acid or peptide residue, wherein Y and Z cannot simultaneously represent an oxygen atom or a radical â€”S(O)tâ€”, or a salt or chiral analogue of said compound.