Patent ID: 6011069
Filing Date: 2000-01-04
Classification: A61K

Abstract:
A method for reducing multidrug resistance in cancer therapy or enhancing the activity of an anti-cancer agent, comprising: administering to a patient in need thereof an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR30## wherein n is an integer of 5 to 12,R.sub.1 and R.sub.2 are each independently benzyl, of which a phenyl ring may be substituted by 1 to 5 substituents selected from hydroxy, (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy and halogen, and/or by methylenedioxy, with the proviso that R.sub.1 and R.sub.2 are simultaneously not a compound of formula (II): ##STR31##