Patent ID: 8062654
Filing Date: 2011-11-22
Classification: A61K,A61L,A61P,D01F,D06M

Abstract:
1. A method of manufacturing a fiber comprising, dissolving a biodegradable polymer in a first solvent to form a polymer solution, wherein said first solvent is poorly miscible in water; preparing a solution comprising a gel or hydrogel; promoting the internal gelation of the gel or hydrogel using a divalent cation; co-extruding the polymer solution and the solution comprising the gel or hydrogel into a coagulating bath, wherein the coagulating bath comprises a second solvent that is highly miscible with the first solvent; and forming at least one bicomponent fiber having a core-in sheath configuration, wherein the fiber comprises a first component and a second component, and wherein said first component is a biodegradable polymer and said second component comprises a gel or a hydrogel.