Patent ID: 6521241
Filing Date: 2003-02-18
Classification: A61K,A61L,A61P,A61Q

Abstract:
A skin irritant sequestering composition consisting essentially of a substrate and both a hydrophilic sequestering agent that sequesters skin irritants and a hydrophobic sequestering agent that sequesters skin irritants, wherein the skin irritant sequestering agents are present in an amount between about 0.01% and about 1.0% by weight of the composition, and at least one of the skin irritant sequestering agents can bind irritants present in at least one of nasal secretions, bodily wastes, vaginal fluids, perspiration, and the environment, such irrtants including at least one of a group consisting of cytokines, eicosanoids, enzymes, superantigens, proteases, lipases, glycosidases, bile aids, endotoxins, bacterial by-products, and combinations thereof; and the hydrophilic sequestering agent is selected from the group consisting of clays, bentonite, kaolinite, laponite, zeolite, montmorillonite, beidelite, hectorite, saponite, stevensite, calcium carbonate, talc, silica, titanium oxides, hydroxyapatite, alumina, aluminum silicate surfactants, calcium silicate, activated carbon, pearl starch, calcium sulfate, antibodies, ion-exchange materials, cyclodextrins, lectins, Lewis acid/base materials, activated charcoal, glass microspheres, diatomaceous earth reactions, refractory metal oxides, and combinations thereof, and the hydrophobic sequestering agent is selected from the group consisting of modified clay, modified silica, modified titanium oxides, modified refractory metal oxides, cyclodextrins, and combinations thereof.