Patent ID: 6486323
Filing Date: 2002-11-26
Classification: C12P

Abstract:
A process for producing an optically active tropinonemonocarboxylic acid ester compound which comprises subjecting a tropinonedicarboxylic acid ester compound represented by the following formula (1): wherein Râ€² is an alkyl group, an aralkyl group or an amino-protecting group selected from lower aliphatic acyl groups, aromatic acyl groups, lower alkoxycarbonyl groups, aralkyloxycarbonyl groups, aryloxycarbonyl groups and tri-lower-alkylsilyl groups, and R is an alkyl group or an aralkyl group, to asymmetric dealkoxycarbonylation in the presence of an enzyme to obtain an optically active tropinonemonocarboxylic acid ester compound represented by the following formula (2): wherein R and Râ€² are as defined above.