Patent ID: 6229016
Filing Date: 2001-05-08
Classification: A61P,C07D

Abstract:
A compound of Formula V: ##STR39##wherein A is an aromatic moiety selected from the group consisting of: ##STR40##wherein:X.sub.1, X.sub.2, and X.sub.3 are each individually selected from the group consisting of C or N wherein at least one of X.sub.1, X.sub.2 and X.sub.3 is N;X.sub.4 and X.sub.5 are each individually selected from the group consisting of C, N, O, and S wherein at least one of X.sub.4 and X.sub.5 is N, O, or S;R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, and R.sub.8 are each independently selected from the group consisting of H, alkyl, hydroxyl, alkoxyl, aryloxyl, halo, amino, alkylamino, dialkylamino, or nitro, or alternatively, two adjacent R groups together may form a bridging group selected from the group consisting of alkyldienyl, alkyleneoxy, alkylenedioxy, alkyleneimine, and alkylenediimine; andthe dashed line indicates that the bond may be a double bond or a single bond,with the provisos that:when any of X.sub.1, X.sub.2, X.sub.3, X.sub.4, or X.sub.5 is C, the dashed lines connected thereto are double bonds;when any of X.sub.1, X.sub.2, or X.sub.3 is N, the dashed lines connected thereto are double bonds and the R group attached at that position is absent;when either X.sub.4 or X.sub.5 is N, the dashed lines connected thereto may be single bonds or double bonds, and when the dashed line is a double bond, the R group attached at that position is absent; andwhen either X.sub.4 or X.sub.5 is O or S, the dashed lines connected thereto are single bonds and the R group attached at that position is absent.