Patent ID: 8546371
Filing Date: 2013-10-01
Classification: A61K,A61P

Abstract:
1. A composition comprising: a glycolipid simulator of NKT cells; and a nanoparticle covalently or non-covalently conjugated with the glycolipid; wherein the glycolipid is selected from the group consisting of 6-aminoethoxy-6-deoxy-alpha-galactosylceramide, 6-aminopropyl-6-deoxy-alpha-galactosylceramide, 6-aminobutyloxy-6-deoxy-alpha-galactosylceramide, amino-acid-6-aminoethoxy-6-deoxy-alpha-galactosylceramide, amino-acid-6-aminopropyl-6-deoxy-alpha-galactosylceramide, amino-acid-6-aminobutyloxy-6-deoxy-alpha-galactosylceramide, mini-PEG-6-aminoethoxy-6-deoxy-alpha-galactosylceramide, mini-PEG-6-aminopropyl-6-deoxy-alpha-galactosylceramide, and mini-PEG-6-aminobutyloxy-6-deoxy-alpha-galactosylceramide.