Patent ID: 6239116
Filing Date: 2001-05-29
Classification: A61K,A61P,C07H,C12N,C12Q,Y02A

Abstract:
A method for inducing Il-6 in a subject comprisingadministering to the subject an effective amount to induce Il-6 in the subject of an immunostimulatory nucleic acid, having a sequence comprising:5'X.sub.1 X.sub.2 CGX.sub.3 X3'wherein C is unmethylated, wherein X.sub.1, X.sub.2 and X.sub.3, X.sub.4 are nucleotides, and wherein the 5' X.sub.1 X.sub.2 CGX.sub.3 X.sub.4 3' sequence is a non-palindromic sequence.