Patent ID: 9056136
Filing Date: 2015-06-16
Classification: A61K

Abstract:
1. A compound having the structure of formula I or a pharmaceutically acceptable salt thereof: wherein: R1 is hydrogen, hydroxyl, tosylate, mesylate, triflate, a positron emitting radionuclide selected from R2 and R3 are independently selected from a lower alkyl having 1 to 5 carbon atoms and a hydroxyalkyl, or R2 and R3 are linked to form a five-, six-, or seven-membered heterocyclic ring comprising at least one nitrogen atom; wherein: i) when R1 is hydrogen, at least one of R2, R3, or said heterocyclic ring comprises a substituent selected from a halogen, a positron emitting radionuclide selected from ii) when R1 is hydroxyl, R2 and R3 are linked to form a five-, six-, or seven-membered heterocyclic ring comprising at least one nitrogen atom, wherein said heterocyclic ring comprises a substituent, wherein said substituent is a halogen, a positron emitting radionuclide selected from any one of