Patent ID: 7388021
Filing Date: 2008-06-17
Classification: A61P,C07C,C07D,C07F

Abstract:
1. A compound Formula (I): or a stereoisomer or pharmaceutically acceptable salt, or solvate thereof, wherein: ring A is phenyl substituted with 0-5 R ring B is selected from the group consisting of: and is substituted with 0-3 R W is O or S; X Y is O, S, NH, —OCR R alternatively, two R R R alternatively, when two R R alternatively, two R R R R R R alternatively, R R R R C 2-6 alkenyl substituted with 0-2 R a , C 2-6 alkynyl substituted with 0-2 R a , or —(CH 2 ) r -phenyl substituted with 0-2 R b ; R alternatively, R alternatively, two R R R R R R R R R R R R n, at each occurrence, is selected from 0, 1, 2, 3, and 4; p, at each occurrence, is selected from 0, 1, and 2; r, at each occurrence, is selected from 0, 1, 2, 3, and 4; s, at each occurrence, is selected from 0, 1, 2, and 3; and t, at each occurrence, is selected from 1, 2, 3, and 4; provided that: (i) when ring B is b) Y is S, ring A is phenyl, then R (ii) when ring B is and Y is O, then ring A is other than 3-CN-phenyl; or (iii) when ring B is and Y is S, then ring A is other than phenyl or substituted phenyl.