Patent ID: 6329183
Filing Date: 2001-12-11
Classification: C08G,C12N,C12P

Abstract:
A method for producing polyhydroxyalkanoates comprising providing organisms which express enzymes selected from the group consisting of acyl-CoA transferase, acyl-CoA synthetase, .beta.-ketothiolase, acetoacetyl-CoA reductase, and polyhvdroxyalkanoate synthase, and which are genetically engineered to express enzymes selected from the group consisting of dehydratases glycerol-3-phosphate dehydrogenase and glycerol-3-phosphatase,providing diols which can be converted into 3-hydroxypropionate or 3-hydroxyvalerate monomers by enzymes expressed by tile organisms, andculturing the organisms under conditions wherein 3-hydroxypropionate or 3-hydroxyvalerate is polymerized to form polyhydroxyalkanoates.