Patent ID: 8193214
Filing Date: 2012-06-05
Classification: A61P,C07D

Abstract:
1. A compound of the formula (I): R1 and R2 are independently hydrogen, halogen, trihaloalkyl, trihaloalkoxy, cyano, hydroxyl, C wherein each group is optionally independently substituted with one to three substituents chosen from C A is C optionally substituted with one to three substituents chosen from halogen, C E is —COORe, —SO G is C M is a methylene group, oxygen, or —S(O) J is an optionally mono- or poly-substituted aromatic carbocycle or a heteroaromatic group having 4-10 carbon atoms containing one or more hetero atoms chosen from the group consisting of an oxygen atom, a nitrogen atom and a sulfur atom in its ring(s); each substituent on said aromatic or heteroaromatic groups is chosen from halogen, hydroxyl, cyano, C Ra, and Rc are each independently C1-3 alkyl or hydrogen; or the pharmaceutically acceptable salts thereof.