Patent ID: 6348481
Filing Date: 2002-02-19
Classification: A61K

Abstract:
A method for the prophylaxis or treatment of angiotensin II-mediated disease in a mammal in need thereof which comprises administering an effective amount of at least one of(Â±)-1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1[[2â€²-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate, 2-ethyoxy-1-[[2â€²-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid, or 2-ethoxy-1-[[2â€²-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]]-1H-benzimidazole-7-carboxylic acid, or a pharmaceutically acceptable salt thereof, in combination with an effective amount of furosemide.