Patent ID: 6334980
Filing Date: 2002-01-01
Classification: B01J,G01N

Abstract:
Apparatus having microfabricated chambers for conducting biochemical analysis, comprising:a flexible substrate of the kind used in flexible circuit manufacturing technology comprising an ablatable polymeric material having a first major face and a bottom surface; a plurality of ablated miniature reaction chambers spaced apart in the first major face, said chambers being produced by ablation; a metallic layer fixed to the substrate and associated with each of the plurality of reaction chambers, the metallic layer comprising a plurality of independently controllable heaters configured to raise the temperature of the reaction chamber which a given heater is associated with; a plurality of ablated analysis chambers spaced apart in the first major face of the substrate, each being in fluid communication with a reaction chamber, said analysis chambers being produced in the substrate by ablation; each reaction chamber and analysis chamber having a lower surface in the substrate; and a protective cover layer positioned over the reaction chambers.