Patent ID: 8080253
Filing Date: 2011-12-20
Classification: A61K,A61P,C07K,C12N

Abstract:
1. A peptide comprising: a) at least one VEGF epitope consisting of amino acids 102 through 122 of SEQ ID NO: 1; b) a helper T cell epitope selected from the group consisting of TT (SEQ ID NO: 3), TT1 (SEQ ID NO: 4), P2 (SEQ ID NO: 5), P30 (SEQ ID NO: 6), MVF (SEQ ID NO: 7), HBV (SEQ ID NO: 8), and CSP (SEQ ID NO: 9); and c) a linker consisting of Gly-Pro-Ser-Leu (SEQ ID NO: 10) joining the at least one VEGF epitope to the helper T cell epitope, wherein the linker is operatively linked to the C-terminus of the at least one VEGF epitope and operatively linked to the N-terminus of the helper T cell epitope.