Patent ID: 8712519
Filing Date: 2014-04-29
Classification: A61N

Abstract:
1. A method for controlling therapy provided by an implantable cardiac stimulation device to reduce mechanical dyssynchrony, the method comprising: detecting an interventricular cardiogenic impedance signal (Z deriving a measure of interventricular fractionation from the interventricular waveform morphology, wherein interventricular fractionation quantifies the features of the interventricular waveform morphology of individual heartbeats corresponding to periods of time when chambers of the heart are not beating uniformly due to mechanical dyssynchrony; and adjusting therapy provided by the device based on the interventricular cardiogenic impedance signal (Z wherein the features of the interventricular waveform morphology corresponding to periods of time when chambers of the heart are not beating uniformly due to mechanical dyssynchrony include a plurality of additional notches within an individual heartbeat arising due to mechanical dyssynchrony and wherein therapy is adjusted to reduce at least one of the plurality of additional notches within the individual heartbeat to reduce interventricular fractionation and reduce mechanical dyssynchrony.