Patent ID: 8946277
Filing Date: 2015-02-03
Classification: A61K,A61P

Abstract:
1. An implantable drug depot for reducing or treating pain in a patient in need of such treatment, the implantable drug depot comprising clonidine in an amount from about 1 wt. % to about 15 wt. % of the drug depot, and a biodegradable polymer, wherein the drug depot has a surface that releases a burst dose of clonidine in an amount of from about 5% to about 20% by weight based on the total weight of clonidine in the depot within 24 hours and an effective amount of clonidine over a period of at least three days and the biodegradable polymer has an inherent viscosity of from about 0.45 dL/g to about 0.55 dL/g and comprises poly(D,L-lactide), and the clonidine comprises clonidine hydrochloride.