Patent ID: 7572937
Filing Date: 2009-08-11
Classification: C07C

Abstract:
1. A process for producing an amino acid comprising the following reaction steps: a) amidocarbonylation reaction, wherein an aldehyde is reacted in an organic solvent with an amide and carbon monoxide and hydrogen to give an N-acyl amino acid in the presence of a transition metal carbonyl catalyst, b) Separating and recovering the formed N-acyl amino acid from the reaction mixture; and c) hydrolysis of the recovered N-acyl amino acid in an aqueous medium to obtain the corresponding amino acid; c1) recovery and recycling the catalyst; and, d) reuse of the reaction mixture of step a) comprising the catalyst and solvent after separation of the N-acyl amino acid by feeding into the amidocarbonylation step a) optionally after supplementing lost solvent and spent catalyst.