Patent ID: 8415368
Filing Date: 2013-04-09
Classification: A61P,C07D

Abstract:
1. A method of treating gastritis, functional dyspepsia, gastric cancer, stomach MALT lymphoma, gastric hyperacidity or upper gastrointestinal hemorrhage due to peptic ulcer, acute stress ulcer, hemorrhagic gastritis or invasive stress, which comprises administering an effective amount of a compound represented by the formula (I): wherein R 1 is a monocyclic nitrogen-containing heterocyclic group optionally condensed with a benzene ring or a heterocycle, the monocyclic nitrogen-containing heterocyclic group optionally condensed with a benzene ring or a heterocycle optionally has substituent(s), R 2 is an optionally substituted C 6-14 aryl group, an optionally substituted thienyl group or an optionally substituted pyridyl group, R 3 and R 4 are each a hydrogen atom, or one of R 3 and R 4 is a hydrogen atom and the other is an optionally substituted lower alkyl group, an acyl group, a halogen atom, a cyano group or a nitro group, and R 5 is an alkyl group, or a salt thereof or a prodrug thereof to a mammal.