Patent ID: 7335727
Filing Date: 2008-02-26
Classification: A61K,A61P,C07K,C12N

Abstract:
1. A method of inhibiting fusion of HIV with a biological membrane comprising administering an effective amount of a composition comprising a fusion inhibitor that comprises an amino acid sequence as follows: wherein X is either an amino group or -X1-X2, wherein X1 is an imino group, and X2 is selected from a group consisting of an acetyl group, a hydrophobic group, and a macromolecular carrier group; and Z is either a carboxyl group or -Z1-Z2, wherein Z1 is a carbonyl group and Z2 is selected from a group consisting of an amino group, a tert-butyloxycarbonyl group, a hydrophobic group, and a macromolecular carrier group.