Patent ID: 7435540
Filing Date: 2008-10-14
Classification: A61P,G01N

Abstract:
1. A method for detecting a PrP Sc in a biological sample, said method comprising the steps of: (a) contacting said biological sample with a peptide consisting of up to 25 amino acids and comprising YYX 1 X 2 YYX 3 YY (SEQ ID NO:1), wherein X 1 , X 2 and X 3 are all R (SEQ ID NO:2) or wherein X 1 , X 2 , and X 3 are all A (SEQ ID NO:3) under conditions that allow for complex formation between said peptide and a PrP Sc polypeptide or fragment thereof, and (b) detecting said complex as an indication that said PrP Sc is present in said biological sample.