Patent ID: 8551517
Filing Date: 2013-10-08
Classification: A61K,A61L

Abstract:
1. A substrate for multiple releases of active agents comprising: a coacervate layer comprising an anionic surfactant present in an amount of from about 50% (by weight of the coacervate layer) to about 99.9% (by weight of the coacervate layer), and a cationic surfactant present in an amount of from about 0.1% (by weight of the coacervate layer) to about 50% (by weight of the coacervate layer); a first polymer matrix layer having at least a first active agent disposed therein, wherein the first active agent is released when the first polymer matrix dissolves; a second polymer matrix layer having at least a second active agent disposed therein, wherein the second active agent is released when the second polymer matrix dissolves; and wherein the coacervate layer is disposed between and adheres together the first polymer matrix layer and the second polymer matrix layer; wherein the first polymer matrix is configured to dissolve prior to the dissolution of the coacervate layer, and the coacervate layer is configured to dissolve prior to the dissolution of the second polymer matrix; and wherein the first active agent and the second active agent are different active agents.