Patent ID: 6127370
Filing Date: 2000-10-03
Classification: A61K,A61P

Abstract:
A method for treating Alzheimer's disease or inhibiting microvascular events leading to neurodegeneration, which comprises administering to a patient in need of treatment a therapeutically effective amount of a drug which causes a reduction in at least moderately elevated blood levels of homocysteine or modifies the toxic effects of at least moderately elevated blood levels of homocysteine on the vasculature or on nerve cells in the brain, wherein the drug employed is a nitric oxide donor, a NEP/ACE inhibitor, an ACE inhibitor or angiotensin II antagonist, betaine or vitamin B.sub.6 or a combination of two or more thereof, or a combination of any one or more of the above with folic acid, a folate or a derivative thereof.