Patent ID: 7807198
Filing Date: 2010-10-05
Classification: A61K,A61P,B82Y,C08B,C08G,C12N,C12Y

Abstract:
1. A composition comprising: a linear cyclodextrin-containing polymer, a therapeutic agent, and an inclusion complex of said polymer and a complexing agent, wherein the complexing agent comprises a ligand for cell targeting, and the polymer has host functionality, and wherein said complexing agent is a compound of the formula: wherein J is —NH—, —C(═O)NH—(CH —NH(C═O)—CH(R Ad is adamantyl; R PEG is —O(CH L is H, —NH Functional Group comprises a ligand for cell targeting; a is 0 or 1; b is 0 or 1; d ranges from 0 to 6; e ranges from 1 to 6; n ranges from 0 to 6; y is 1; and x is 1.