Patent ID: 7112412
Filing Date: 2006-09-26
Classification: A61K,A61P,C07K,G01N,Y10S

Abstract:
1. A method of detecting normal, benign hyperplastic, or cancerous prostate cells in a human subject, comprising: providing an antibody or antigen binding portion thereof which competes for binding to prostate specific membrane antigen (PSMA) with a monoclonal antibody selected from the group consisting of an E99, a J415, a J533, and a J591 monoclonal antibody, wherein the antibody or antigen binding portion thereof is bound to a label effective to permit detection of normal, benign hyperplastic, or cancerous prostate cells; administering the antibody or antigen binding portion thereof to the human subject; and detecting the presence of the normal, benign hyperplastic, or cancerous prostate cells by detecting the label.