Patent ID: 6391657
Filing Date: 2002-05-21
Classification: C07K

Abstract:
A process for removing unwanted substances from a liquid substance mixture comprising:binding one of said unwanted substances to a ligand to form a complex to increase the size of one of said unwanted substances, filtering the liquid substance mixture through a filter having an average pore diameter sufficient to filter out said complex of unwanted substance and ligand, and recovering the resulting filtrate, wherein the ligand is chosen from a CD4 receptor, a sialic acid or a derivative thereof, a heparin sulfate, a C3d complement receptor, an acetylcholine receptor, ICAM-1, a ganglioside, an IgA receptor, an epidermal growth factor receptor, a &bgr;-adrenergic receptor, an H-2 antigen, and an immunoglobulin superfamily protein.