Patent ID: 7666914
Filing Date: 2010-02-23
Classification: A61K,A61P,Y10S

Abstract:
1. A preparation for topically delivering and localizing at least one therapeutic agent, comprising: a vasoconstrictor for retarding vascular dispersion of a therapeutic agent, selected from the vasoconstrictor group consisting of at least one of: phenylephrine, ephedrine sulfate, epinephrine, naphazoline, and oxymetazoline; and a penetration enhancer for facilitating penetration of said vasoconstrictor and said therapeutic agent through a patient's skin, selected from the penetration enhancer group consisting of at least one of: lecithin and dimethylsulfoxide; wherein: said therapeutic agent is selected from at least one therapeutic agent in at least one of the following therapeutic agent groups: (a) a local anesthetic selected from the group consisting of: bupivacaine, mepivacaine, levobupivacaine, ropivacaine, chloroprocaine, procaine, lidocaine, etidocaine, benzocaine, tetracaine, and prilocaine; (b) a quick-onset, short-acting non-steroidal anti-inflammatory agent selected from the group consisting of: ketoprofen, diclofenac, diflunisal, etodolac, fenoprofen, flurbiprofen, ibuprofen, indomethacin, and tolmetin; (c) a long-acting non-steroidal anti-inflammatory agent selected from the group consisting of: piroxicam, celecoxib, meloxicam, nabumetone, naproxen, oxaprozin, rofecoxib, sulindac, and valdecoxib; (d) an antiviral agent selected from the group consisting of: 2-deoxy-d-glucose, podofilox, acyclovir, penciclovir, and docosanol.