Patent ID: 6692914
Filing Date: 2004-02-17
Classification: C08F,G01N,Y10T

Abstract:
A sensor for detecting a biological molecule in an aqueous sample comprising:(A) a substrate having a surface; and (B) a plurality of random copolymer chains bound to said surface, each of said plurality of random copolymer chains comprising (i) a water-soluble or water-dispersible segment and (ii) at least one probe bonded to said water-soluble or water-dispersible segment, the probe being selective for the biological molecule, wherein said random copolymer chains are synthesized according to a process comprising: (i) bonding an initiator to said surface at one or more points to form a derivatized surface; (ii) contacting said derivatized surface with a composition comprising a water-soluble or water-dispersible free radically polymerizable monomer under reaction conditions to form bound random copolymer chains comprising one or more functional groups on said chains that are available for reaction with the probe; and, (iii) bonding said probes to said bound random copolymer chains through said functional groups.