Patent ID: 9085561
Filing Date: 2015-07-21
Classification: A61P,C07D

Abstract:
1. A compound of Formula (I): or a pharmaceutically acceptable salt thereof wherein: Y Q each R a is an integer selected from 0, 1, and 2; E is N or C(R G, M, and U are independently selected from N(R J is N(R W is N(R each dashed line of the Q each R each R each c is independently an integer selected from 0, 1, 2, and 3; each d is independently an integer selected from 0, 1, and 2; provided that the ring atoms of the Q R j is an integer selected from 0, 1, 2, and 3; A and B are independently selected from: wherein the A-B bridge can be in the endo- or exo- configuration with respect to the 6-membered, nitrogen-containing ring that is fused to the Q R R each R Z is —[(C R —Z—R —Z—R each R each R each R each R each R if h is 0, then R if h is 1, then R otherwise, wherein Z is —[(C each R R R m is an integer selected from 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, and 11; n is an integer selected from 0, 1, 2, 3, 4, 5, 6, 7, 8, and 9; e and f are each an integer independently selected from 0, 1, 2, 3, 4, and 5 provided that 2≦(e+f)≦5; each p is an integer independently selected from 0, 1, 2, 3, and 4; each T each T each V each halo is independently —F, —Cl, —Br, or —I.