Patent ID: 6068766
Filing Date: 2000-05-30
Classification: G01N

Abstract:
An apparatus for sealing a sample-conveying conduit to a chromatography cartridge containing a media bed comprising:a first head piece and a second head piece, both of which are elongated along a longitudinal axis and are sized to fit slidably into the cartridge, said first head piece having a body, a first compression face, and a contact face, said second head piece having a second compression face and a compression force receiving member, said body defining an elongate flow channel along said axis; andan elastomeric sealing member at least part of which is situated between said first compression face and said second compression face, said elastomeric sealing member being sized to fit slidably into the cartridge when said elastomeric sealing member is not compressed, said elastomeric sealing member capable of being compressed, between said first and second compression faces, by moving said second head piece toward the media bed so that said contact face of said first head piece presses against the media bed, causing said elastomeric sealing member to expand laterally to form a seal with the cartridge, said first and second head pieces and said elastomeric sealing member disposed so that said second head piece interacts with said first head piece only through said elastomeric sealing member so that compressive force from said second head piece is transmitted through said elastomeric sealing member and through said first head piece to the media bed, when said elastomeric sealing member is compressed.