Patent ID: 6399611
Filing Date: 2002-06-04
Classification: A61P,C07D

Abstract:
A compound of the formula I in whichR1 and R2 in each case independently of one another are H or A, R3 and R4 in each case independently of one another are â€”OH, â€”OR10, â€”Sâ€”R10, â€”SOR10, â€”SO2R10, Hal, â€”NO2, â€”NH2, â€”NHR10 or â€”NR10R11, R5 is a phenyl radical which is mono- or disubstituted by R6 and/or R7, Q is absent or is alkylene having 1-6 C atoms, R6 and R7 in each case independently of one another are â€”NH2, â€”NR8R9, â€”NHR10, â€”NR10R11, â€”NO2, Hal, â€”CN, â€”COOH or â€”COOA, R8 and R9 in each case independently of one another are H, â€”COOA, â€”SOâ€”A, â€”SO2A, â€”CONH2, â€”CONHA, â€”CONA2, â€”COâ€”COOH, â€”COâ€”COOA, â€”COâ€”CONH2, â€”COâ€”CONHA, â€”COâ€”CONA2, or acyl having 1-8 C atoms which is optionally substituted by 1-5 F and/or Cl atoms, A is alkyl having 1 to 6 C atoms which can be substituted by 1-5 F and/or Cl atoms, R10 and R11 both are A, cycloalkyl having 3-7 C atoms, methylenecycloalkyl having 4-8 C atoms or alkenyl having 2-8 C atoms and Hal is F, Cl, Br or I, and their physiologically acceptable salts.