Patent ID: 7671175
Filing Date: 2010-03-02
Classification: A23K,A23L,A61K,A61P,C07K

Abstract:
1. A polypeptide having antimicrobial activity, which comprises the amino acid sequence of SEQ ID NO: 2: wherein Xaa at position 5 is Ala, Arg, Asn, Asp, Gln, Gly, His, Leu, Lys, Met, Ser, Tyr or Val; Xaa at position 9 is Ala, Arg, Asn, Asp, Cys, Gln, Gly, His, lle, Leu, Lys, Met, Phe, Pro, Ser, Thr, Tyr or Val; Xaa at position 11 is Ala, Arg, Asn, Asp, Cys, Gly, His, lle, Leu, Lys, Met, Phe, Pro, Ser, Thr, Trp, Tyr or Val; Xaa at position 13 is Ala, Arg, Glu, Gly, Leu, Lys, Met, Phe, Ser, Thr, Trp, Tyr or Val; Xaa at position 14 is Ala, Arg, Cys, Gln, Gly, His, lle, Leu, Lys, Met, Phe, Pro, Ser, Thr, Trp, Tyr or Val; Xaa at position 17 is Ala, Arg, Asn, Gin, Glu, His, lle, Lys, Phe, Ser, Thr, Trp, Tyr or Val; Xaa at position 20 is Arg, Gin or Lys; Xaa at position 23 is Arg, Lys or Thr; Xaa at position 24 is Ala, Arg, Asn, Gin, Gly, His, lle, Lys, Phe, Pro, Ser, Thr or Tyr; Xaa at position 26 is Arg, Cys, His, Lys, Phe or Thr; Xaa at position 31 is Ala, Arg, Asn, Gln, Glu, Gly, His, lle, Lys, Ser, Thr, Tyr or Val; Xaa at position 32 is Arg, Lys or Thr; Xaa at position 33 is Ala, Arg, Asn, Gin, Glu, Gly, Lys, Ser or Thr; Xaa at position 36 is Arg, Gin, lle, Leu, Lys, Met, Thr or Val; and Xaa at position 38 is Arg, Asn, His or Lys; which has less than 100% identity with amino acids 1 to 40 of SEQ ID NO: 1.