Patent ID: 7214824
Filing Date: 2007-05-08
Classification: A61P,C07C,C07D

Abstract:
1. A compound of the formula (I): wherein R 1 represents a (C 1 –C 6 )alkyl group; R 2 represents a hydrogen atom, a halogen atom, a hydroxy group, a (C 1 –C 6 )alkyl group or a (C 1 –C 6 )alkoxy group; R 3 , R 4 , R 5 and R 6 each independently rpresents a hydrogen atom, a (C 1 –C 6 )alkyl, or a halogen atom; R 7 represents a hydrogen atom, a halogen atom, a hydroxy group, a (C 1 –C 6 )alkyl group optionally substituted with a piperidino group, a (C 1 –C 6 )alkoxy group optionally substituted with a 3–7 membered cycloalkyl ring, a hydroxy(C 1 –C 6 )alkoxy group, a (C 1 –C 6 ) alkoxy-(C 1 –C 6 )alkyl group, a (C 1 –C 6 )alkoxy-(C 1 –C 6 )alkoxy group, a halo (C 1 –C 6 )alkyl group, a (C 1 –C 6 )alkylthio group, a (C 1 –C 6 )alkylsulfinyl group or a (C 1 –C 6 )alkylsulfonyl group; R 8 represents a (C 1 –C 6 )alkyl group, a halo(C 1 –C 6 )alkyl group, a (C 1 –C 6 )alkoxy group, a hydroxy(C 1 –C 6 )alkoxy group, a (C 1 –C 6 )alkoxy-(C 1 –C 6 )alkyl group or a (C 1 –C 6 )alkoxy-(C 1 –C 6 )alkoxy group; or R 7 and R 8 , when adjacent to each other, taken together with the carbon atoms to which they are attached form a 5–8 membered carbocyclic or heterocyclic ring, wherein the carbocyclic ring or the heterocyclic ring is unsubstituted or substituted with one or more substituents selected from the group consisting of a hydroxy group, a (C 1 –C 6 )alkyl group, a (C 1 –C 6 )alkoxy group and a hydroxy(C 1 –C 6 )alkyl group; and R 9 represents a hydrogen atom or a halogen atom; or a pharmaceutically acceptable salt or solvate thereof.