Patent ID: 7817266
Filing Date: 2010-10-19
Classification: G01N

Abstract:
1. A small internal volume cell comprising a sample substrate at a lower extent thereof, said small internal volume cell further comprising laterally separated fluid entry and exit ports at an upper extent thereof and input and output apertures for entering and exiting a beam of electromagnetic radiation affixed to laterally separated sides thereof, to allow entry and exit at known angles-of-incidence and reflection, as viewed in frontal elevation; said small internal volume cell being characterized by the presence of at least one bubble accumulating trap region in a fluid exit pathway to said exit port for accumulating bubbles produced during the entry and exit of fluid from said small volume cell; such that in use, while fluid is caused to enter said input port and contact said sample substrate, then exit via said exit port, a beam of electromagnetic radiation is caused to enter said input aperture, reflect from said sample substrate at or near the location at which said fluid is caused to contact said sample substrate, and exit said output aperture.