Patent ID: 8834840
Filing Date: 2014-09-16
Classification: A61K,C07K,G01R

Abstract:
1. A composition comprising a plurality of different amphiphilic peptide compounds, each said compound comprising a peptide component and a hydrophobic component comprising a hydrocarbon moiety selected from about C 6 to about C 24 linear alkyl moieties and about C 6 to about C 24 branched alkyl moieties, said hydrocarbon component coupled to said peptide component at one of the C-terminus and N-terminus thereof; and at least one said compound a branched amphiphilic peptide compound comprising a peptide component comprising residues selected from alanine, glycine, cysteine, leucine and combinations thereof and at least one amino acid residue comprising a pendant amino group coupled to a portion of said peptide component non-linear thereto, and at least one amino acid residue comprising a pendant amino group conjugated with a chelator component of a gadolinium, iron or manganese magnetic resonance contrast agent, said chelator component at a position on said peptide component not at the end of said non-linear portion.