Patent ID: 6998417
Filing Date: 2006-02-14
Classification: A23G,A23K,A61K,A61P,C07D,C07H,C11B

Abstract:
1. A method of therapeutic or prophylactic treatment of atherosclerosis, thrombosis, heart attack, stroke or vascular circulation problems comprising administering to a subject in need thereof an effective amount of a polymeric compound of the formula A n or a pharmaceutically acceptable salt thereof: wherein n is an integer from 2 to 18, such that there is at least one terminal monomeric unit A, and one or a plurality of additional monomeric units; R is 3-(α)—OH, 3-(β)—OH; bonding between adjacent monomers takes place at positions selected from the group consisting of 4, 6 and 8; a bond of an additional monomeric unit in position 4 has alpha or beta stereochemistry; X, Y and Z are selected from the group consisting of monomeric unit A, hydrogen, and a sugar, with the provisos that as to the at least one terminal monomeric unit, bonding of the additional monomeric unit thereto is at position 4 and optionally y=Z=hydrogen; wherein the subject is a human or a veterinary animal.