Patent ID: 7439345
Filing Date: 2008-10-21
Classification: C12Q

Abstract:
1. A cyclohexylnucleooligoamide (CAN) oligomer, comprising monomeric subunits independently selected from a peptide nucleic acid (PNA) monomer and a monomeric subunit of formula (I): wherein: R R R nucleobase is selected from the group consisting of 1-thyminyl, 1-uracilyl, 9-adeninyl, 1-cytosinyl, 9-guaninyl, 1-isocytosinyl, 9-isoguaninyl, 9-xanthinyl, and 9-hypoxanthinyl, wherein each nucleobase is optionally provided with one or more protective groups; wherein: at least one monomeric subunit of the oligomer is a monomeric subunit of formula (I); the monomeric subunits of the oligomer are linked by amide bonds; and the monomeric subunit(s) of formula (I) in the oligomer are linked 2′→4′.