Patent ID: 6306853
Filing Date: 2001-10-23
Classification: C07D

Abstract:
A compound having the formula (I): ##STR319##whereinR.sub.1 represents a phenyl or pyridyl group, wherein the phenyl or pyridyl group is optionally substituted with a C.sub.1 to C.sub.3 lower alkylthio group, a C.sub.1 mto C.sub.3 lower alkyloxy group, a C.sub.1 to C.sub.3 lower alkyl group, a halogen atom, or a heterocyclic group selected from the group consisting of imidzaopyridine, piperazine, imidazole, morphoine, indole, benzimidazole, indazole, thiophene, and 1H-benzotriazole, wherein the heterocyclic group is optionally substituted with a C.sub.1 to C.sub.3 lower alkyl group, a trifluoromethyl group, or a halogen atom;R.sub.2 represents a C.sub.1 to C.sub.5 lower alkyl group;R.sub.3 represents a C.sub.1 to C.sub.8 alkyl, alkenyl or alkynyl group; a C.sub.3 to C.sub.7 cycloalkyl or cycloalkenyl group; or a C.sub.1 to C.sub.4 lower alkyl group or C.sub.2 to C.sub.3 lower alkenyl group substituted with a phenyl, thienyl, furyl, cyclohexyl, naphthyl, indanyl, 1,1a,6,10b-tetrahydrodibenzo[a,e]-cyclopropac[c]ycloheptene-yl, 5H-dibenzo[a,d]cycloheptene-yl group or 10,11-dihydro-5H-dibenzo[a,d]cyclohepten-yl ring group, wherein the ring group is optionally substituted with a halogen atom, C.sub.1 to C.sub.3 lower alkyloxy group, or a C.sub.1 to C.sub.3 lower alkyloxy group substituted with a cycloalkyl or phenyl group;R.sub.4 represents --A--R.sub.5, wherein A represents a C.sub.3 to C.sub.5 alkynylene group having one triple bond; andR.sub.5 represents a pyridyl, quinolyl, isoquinolyl or pyrimidyl group, each of which may be optionally substituted with a C.sub.1 to C.sub.3 lower alkyl group, C.sub.1 to C.sub.3 lower alkoxy group, or a halogen atom.