Patent ID: 8946149
Filing Date: 2015-02-03
Classification: A61K,A61P

Abstract:
1. A method for attenuating or delaying cardiac remodeling, said method comprising: administering to a subject in need thereof an amount of a cardioprotective incretin compound (CIC) effective to prevent a deleterious effect on or improve at least one cardiac parameter in said subject, whereby cardiac remodeling is attenuated or delayed, wherein said subject has experienced, or is experiencing, cardiac remodeling following a myocardial insult; and wherein said CIC is exendin-3, exendin-4, an exendin-3 analog with GLP-1 receptor agonist activity or an exendin-4 analog with GLP-1 receptor agonist activity, and wherein said CIC is administered after the myocardial insult.