Patent ID: 6245799
Filing Date: 2001-06-12
Classification: C07D

Abstract:
A compound of the formula: ##STR29##wherein:X is N--R, O, S(O).sub.m ;m is an integer of 0 to 2;n is an integer of 0 to 4;Ar is an aryl group of 6 to 12 carbon atoms optionally substituted with 1 to 3 groups selected independently from R.sub.3, R.sub.4 and R.sub.5, or a heteroaryl group of 4 to 10 carbon atoms optionally substituted with 1 to 3 groups selected independently from R.sub.3, R.sub.4 and R.sub.5 ;R and R.sub.2 are independently H, straight chain alkyl of 1 to 6 carbon atoms, branched alkyl of 3 to 6 carbon atoms, cycloalkyl of 3 to 6 carbon atoms, alkoxycarbonyl of 1 to 6 carbon atoms, alkylcarbonyl of 1 to 6 carbon atoms, aminocarbonyl, or alkylaminocarbonyl of 1 to 4 carbon atoms;R.sub.1, R.sub.3, R.sub.4 and R.sub.5 are independently H, straight chain alkyl of 1 to 4 carbon atoms, branched alkyl of 3 to 6 carbon atoms, cycloalkyl of 3 to 8 carbon atoms, halogen, alkoxy group of 1 to 4 carbon atoms, haloalkyl of 1 to 4 carbon atoms, hydroxy, nitro, amino, sulfonyl, cyano, carboxy, alkoxycarbonyl of 1 to 4 carbon atoms, alkylcarbonyl of 1 to 4 carbon atoms, aminocarbonyl, or alkylaminocarbonyl of 1 to 4 carbon atoms;or a pharmaceutically acceptable salt thereof.