Patent ID: 6197964
Filing Date: 2001-03-06
Classification: C07B,C07D

Abstract:
A process for the preparation of 2,6-dichloro-5-fluoronicotinonitrile which comprises reacting a reactant component selected from the group consisting of 3-cyano-2-hydroxy-5-fluoropyrid-6-one, tautomers of 3-cyano-2-hydroxy-5-fluoropyrid-6-one, salts of 3-cyano-2-hydroxy-5-fluoropyrid-6-one, and tautomers of 3-cyano-2-hydroxy-5- fluoropyrid-6-one monosodium salts with phosphorus trichloride and chlorine gas in a solvent, adding a basic catalyst at 30-300.degree. C. and then hydrolyzing the product.