Patent ID: 6531502
Filing Date: 2003-03-11
Classification: C07D,C07K,C12N

Abstract:
A compound having the chemical structure: wherein:A is carbon; Q is R0 is selected from the group consisting of hydrogen, alkyl, â€”C(O)R19 and â€”C(O)OR19; R1 is hydrogen, alkyl, alkoxy, halo, aryl, â€”(CH2)nOC(O)R19, C(O)NR19, â€”C(O)OR19 and â€”(CH2)nR20, wherein; R19 is selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl and aryl; n is 1, 2, 3, or 4; R20 is selected from the group consisting of hydroxy, halo, â€”C(O)OR19, â€”OC(O)NR21R22; â€”OC(S)NR21R22, â€”OC(O)NHSO2R21R22 and â€”NR21R22; R2 is selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, trihalomethyl, alkoxy, halo, â€”(CH2)nR20, â€”SO2NR21R22, â€”C(O)OR19, â€”C(O)R19, â€”NHC(O)OR19, â€”NR21R22 and â€”N&boxH;CR23 wherein R21 and R22 are independently selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl and aryl; R23 is selected from the group consisting of alkyl, alkenyl, alkynyl, cycloalkyl and aryl; R3 is selected from the group consisting of hydrogen, alkyl, trihalomethyl, alkoxy, aryl, aryloxy, hydroxy, halo, â€”SO2NR21R22, â€”NHSO2R19, â€”C(O)OR19, â€”NR21R22 and â€”NHC(O)R24, wherein R24 is selected from the group consisting of alkyl, alkenyl, alkynyl and aryl; R4 is selected from the group consisting of hydrogen, alkyl, alkoxy and halo; R10 is selected from the group consisting of alkyl and â€”C(O)OR19; R11 is selected from the group consisting of hydrogen, alkyl and â€”C(O)OR19; R12 is â€”(CH2)nR20; and, physiologically acceptable salts thereof.