Patent ID: 6337317
Filing Date: 2002-01-08
Classification: A61K,A61P,C07K

Abstract:
An isolated peptide having antimicrobial activity and an amino acid sequence selected from the group consisting of:WCFZ5VCZ2RGZ3CRZ2KCRR (SEQ ID NO:14), Z2RWCFRVCYZ3GZ2CZ3Z5Z2CR (SEQ ID NO:15), RRWCFZ5VCZ3RGZ4CYZ4Z4CRZ1 (SEQ ID NO:16), RZ5WCZ3Z2Z3CYRGFCZ3Z2Z5CR (SEQ ID NO:17), RRWCZ3RVCYZ5GFCYRKCR (SEQ ID NO:18), and RRWCFRVCYRGZ3FCYRKCR (SEQ ID NO:19); wherein Z1 is an amino acid residue having a basic side chain or absent, Z2 is an amino acid residue having a basic or aromatic side chain, Z3 is an amino acid residue having a basic side chain, Z4 is arginine, valine or alanine, and Z5 is an amino acid residue having an aromatic or aliphatic side chain.