Patent ID: 7612087
Filing Date: 2009-11-03
Classification: A61K,A61P

Abstract:
1. A pharmaceutical composition comprising a bacterial β-lactamase inhibitory amount of a compound, or a pharmaceutically acceptable salt thereof, of formula (I): wherein R 1 is hydrogen, COOH, CN, COOR, CONR 6 R 7 , (CH 2 ) n′ R 5 or C(═NR 6 )NHR 7 ; R is selected from the group consisting of alkyl containing 1 to 6 carbon atoms optionally substituted by a pyridyl or carbamoyl radical, —CH R n′ is 1 or 2; R R R A is a  group wherein R n is 1; X is a divalent —C(O)—B— group linked to the nitrogen atom by the carbon atom wherein B is a divalent —O—(CH Y is selected from the group consisting of COH, COR, COOR, CONH Y Y Y R R X is —C(O)—O—(CH , or X is —CO—NR