Patent ID: 6361942
Filing Date: 2002-03-26
Classification: C07K,C12Q

Abstract:
A composition comprising;a) at least one component probing polymer wherein the probing polymer comprises: 1) a probing segment that is complementary or substantially complementary to a target sequence; and 2) one or more interacting groups suitable for the formation of a complex with at least one other component polymer that is not the target sequence wherein the probing polymer can perform as a primer in an extension reaction upon hybridization of the probing segment to the target sequence; b) at least one component annealing polymer that is not the target sequence and which, at a minimum, comprises one or more interacting groups wherein the interacting groups of the component polymers form and stabilize the complex; and c) at least one set of donor and acceptor moieties wherein to each of at least two of the component polymers, that are not the target sequence, is linked at least one moiety from the set such that formation of the complex facilitates transfer of energy between donor and acceptor moieties of the set; provided however, that at least one of the component polymers of the composition is a non-nucleic acid polymer.