Patent ID: 6846925
Filing Date: 2005-01-25
Classification: A61K,A61P,C07C,C07D,C07F,C07K

Abstract:
1. A process for preparing a compound of formula (I): or a compound of the formula (I) wherein at least 1 functional group is protected, comprising: a) reacting a compound of formula (X) with a compound of formula (XI): wherein L b) converting one compound of the formula (I) into another compound of the formula (I); or c) when a phosphoryloxy group is desired, reacting the corresponding hydroxy compound with a phosphoramidite, wherein any functional groups are optionally protected; and thereafter, if necessary: i) converting a compound of formula (I) into another compound of formula (I); ii) removing any protecting groups; iii) forming a pharmaceutically acceptable salt, solvate or pro-drug thereof, wherein: R A is —CO—, —C(O)O—, —CON(R a is an integer from 1 to 4 inclusive; R B is —O—, —CO—, —N(R b is 0 or an integer from 1 to 4 inclusive, (provided that when b is 0, B is a single direct bond); D is carboxy, sulpho, tetrazolyl, imidazolyl, phosphoryloxy, hydroxy, amino, R R R R or a pharmaceutically acceptable salt, solvate or pro-drug thereof.