Patent ID: 7910299
Filing Date: 2011-03-22
Classification: A61P,C12Q,Y02A

Abstract:
1. A method for diagnosing severe systemic lupus erythematosus in a human, said method comprising: (a) providing a biological sample comprising peripheral blood mononuclear cells (PBMC) from a human having or suspected of having systemic lupus erythematosus, (b) measuring mRNA expression of a gene in said sample, wherein said gene is interferon, alpha-inducible protein (clone IFI-6-16), and (c) diagnosing said human as having severe systemic lupus erythematosus if the level of said mRNA expression is greater in said sample than in a corresponding control sample, or diagnosing said human as not having severe systemic lupus erythematosus if the level of said mRNA expression is not greater in said sample than in a corresponding control sample.