Patent ID: 6239281
Filing Date: 2001-05-29
Classification: C07D

Abstract:
A process for preparing a carbamoyl pyridinium compound, which method comprises:a) reacting a pyridine sulfonic acid compound with a carbamoyl halide in the presence of an effective amount of a by-product solubilizing solvent and an effective amount of tertiary amine acid scavenger, thereby forming a reaction product comprising a carbamoyl pyridinium compound, a tertiary amine hydrohalide by-product and said by-product solubilizing solvent, wherein said tertiary amine hydrohalide by-product is substantially soluble in said by-product solubilizing solvent and said carbamoyl pyridinium compound is substantially insoluble in said by-product solubilizing solvent; andb) separating said carbamoyl pyridinium compound from said reaction product.