Patent ID: 7955618
Filing Date: 2011-06-07
Classification: A61K,A61P,Y10S

Abstract:
1. A pharmaceutical composition comprising: a corticosteroid in water-soluble form having a water solubility of at least 1 in <10 (w/v), as assessed in water or water buffered at physiologic values, and negatively charged liposomes consisting of cholesterol, non-charged vesicle-forming lipids, amphipathic vesicle-forming lipids derivatized with polyethyleneglycol, said amphipathic vesicle-forming lipids being present in an amount of up to 10 mole percent, and up to 10 mole percent of negatively charged vesicle-forming lipids, wherein said negatively charged liposomes have a selected mean particle diameter in a size range between about 40-200 nm and enclose said corticosteroid.