Patent ID: 8642742
Filing Date: 2014-02-04
Classification: A61K,A61N,A61P,C07K

Abstract:
1. An isolated antibody which binds membrane-bound CEA, wherein the antibody comprises a heavy chain variable region comprising: the heavy chain CDR1 of SEQ ID NO: 1, the heavy chain CDR2 of SEQ ID NO: 13, and a heavy chain CDR3 selected from the group consisting of SEQ ID NO:217, SEQ ID NO:218, SEQ ID NO:219, SEQ ID NO:220, SEQ ID NO:221, SEQ ID NO:222, and SEQ ID NO:223; and a light chain variable region comprising: the light chain CDR1 of SEQ ID NO:39, the light chain CDR2 of SEQ ID NO:49, and the light chain CDR3 of SEQ ID NO:56.