Patent ID: 8221985
Filing Date: 2012-07-17
Classification: G01N

Abstract:
1. A method for determining the relative dilution of a solution containing a ligand which is directed against a target analyte, and a liquid sample containing the target analyte to be analyzed, which target analyte sample is miscible with said ligand solution, at least one of said solution and said sample containing a detectable sensible marker, said method comprising the steps of: a) placing an effective amount of said solution in one area of a planar reaction chamber having a thin through thickness dimension; b) placing an effective amount of said target analyte sample in an adjacent area of said planar chamber; c) allowing or causing said solution and said sample to admix with each other until an admixture gradient is created in a solution-sample mixture in said chamber; d) electronically imaging or scanning said admixture gradient in said chamber between a first location containing an undiluted amount of said solution and a second location containing an undiluted amount of said target analyte sample; and e) calculating a relative concentration or dilution of each of said solution and said sample by measuring the concentration of said detectable sensible marker in said mixture in said imaged area.