Patent ID: 8119681
Filing Date: 2012-02-21
Classification: A61P,C07D

Abstract:
1. A compound of Formula I or a pharmaceutically acceptable salt thereof, wherein A and B are independently selected from the group consisting of: H and F; C, D and E are independently selected from the group consisting of: H, F, —CH F is selected from the group consisting of: a bond, —C(R G is selected from the group consisting of: —O—C(O)—N(R)(R), —O—C(O)—O—R, —C(O)—R, —C(O)—O—R, —C(O)—N(R)(R), —C(O)—N(R)—C(R each R is independently selected from the group consisting of: H, haloC two R groups attached to the same nitrogen atom can be joined together with the nitrogen atom to which they are attached to form a 3- to 7-membered monocyclic ring, said ring optionally substituted with oxo and said ring further optionally substituted with 1 to 3 substituents independently selected from the group consisting of: halo, hydroxyl, C X is selected from the group consisting of: H, C R R substituted aryl and substituted heteroaryl mean aryl and heteroaryl respectively, each substituted with one to three substituents independently selected from the group consisting of: halo, C