Patent ID: 6037345
Filing Date: 2000-03-14
Classification: A61K

Abstract:
A method of treating a mammal sensitive to such a compound having precancerous lesions comprising administering to said mammal a pharmacologically effective amount of a compound of Formula I or pharmaceutically acceptable salt thereof: ##STR2## wherein R.sub.1 is hydrogen, alkyl of 1 to 3 carbon atoms, cyclopentyllmethyl, cyclohexylmethyl, norbornylmethyl, bicyclooctylmethyl, or benzyl, the phenyl of the benzyl optionally being substituted by halogen, trifluoromethyl, nitro, carboxy, or CO.sub.2 Mwherein M is a pharmaceutically acceptable cation; Y is carboxy, carboalkoxy;wherein the alkoxy has 1 to 6 carbon atoms, carbobenzyloxy, carbamoyl N-alkylcarbamoylwherein the alkyl has 1 to 6 carbon atoms, or CO.sub.2 M wherein M is as defined above, and Z is N.