Patent ID: 8725423
Filing Date: 2014-05-13
Classification: G16B

Abstract:
1. A method comprising the following steps: (a) generating a loess-smoothed replication timing profile for a population of cells, (b) comparing the loess-smoothed replication timing profile for the population of cells to loess-smoothed replication timing reference profiles for a plurality of different leukemic cell types, which are contained in a database, (c) based on the comparison of step (b), identifying the population of cells as having a leukemic cell type that is one of the plurality of different leukemic cell types if the loess-smoothed replication timing profile is determined to be substantially the same as the loess-smoothed replication timing reference profile for the leukemic cell type, and (d) displaying the cell type identified in step (c) to a user, wherein steps (a), (b), (c) and (d) are performed by a computer configured to perform steps (a), (b), (c) and (d).