Patent ID: 8673852
Filing Date: 2014-03-18
Classification: A61K,A61P

Abstract:
1. A method of alleviating cerebral ischemia or a stroke in a mammal afflicted with the disorder, the method comprising administering to the mammal a motoneuronotropic factor (MNTF) analog having an amino acid sequence according to SEQ. ID NO:2 and which is capable of effectively and efficiently crossing the blood brain barrier, wherein a dosage for intravenous administration of MNTF analog is selected and the MNTF analog is administered intravenously to said mammal to result in a desired physiological outcome selected from a decrease cerebral infarct volume, ii) an increase in cerebral blood flow, iii) as reduced neurological deficit, or iv) a reduction in neural degeneration or inflammation in cerebral tissue of said mammal.