Patent ID: 7897370
Filing Date: 2011-03-01
Classification: C07K,C12N,C12P

Abstract:
1. A process for producing compound (II-a) or compound (II-b), wherein an isolated transformed cell comprising a DNA having the nucleotide sequence of SEQ ID NO: 43, a culture of the transformed cell, or a treated product of the culture is used as an enzyme source, and the process comprises: allowing compound (I-a) or compound (I-b) to exist in an aqueous medium in the presence of the enzyme source; allowing compound (II-a) or compound (II-b) to be produced and accumulated in said aqueous medium; and collecting compound (II-a) or compound (II-b) from said aqueous medium wherein, the compound (I-a) is a compound represented by the formula (I-a): the compound (I-b) is a lactone form of compound (I-a) and is represented by the formula (I-b): the compound (II-a) is a compound represented by the formula (II-a): the compound (II-b) is a lactone form of compound (II-a) and is represented by the formula (II-b): and wherein R wherein the treated product of the culture of the transformed cell is a treated product selected from the group consisting of cultured cells, dried cells, freeze-dried cells, cells treated with a surfactant, cells treated with an enzyme, cells treated by ultrasonication, cells treated by mechanical milling, cells treated by solvent, a protein fraction of a cell, and immobilized cells.