Patent ID: 7829721
Filing Date: 2010-11-09
Classification: A61K,A61P,C07C

Abstract:
1. A compound of formula (II): in which: X, Y and Z, which may be identical or different, each independently represent a —CH═ group or a nitrogen atom wherein if one of X, Y or Z is nitrogen the other two are —CH═; m is an integer 1, 2, 3, 4 or 5; R1 represents —COOR, —CH in which R represents a hydrogen atom, -alkyl optionally substituted by a halogen atom, —OH, —CN, —Oalkyl, -Aryl, —OR′, —NO or R represents an -aryl, -alkylaryl or -heteroaryl group, each optionally substituted by a halogen atom, —OR, —CN, -Aryl, NO in which R′ represents an -alkyl group optionally substituted by a halogen atom, —OR, —CN, —COOR, —NRR′, —NO R2 represents a halogen atom, —NO each of the R3, which may be identical or different, independently represents a halogen atom, optionally perhalogenated -alkyl, optionally perhalogenated —Oalkyl, —S(O) -aryl, -alkylaryl, or an -alkyl group, each optionally substituted by a halogen atom, —OR, —CN, —NRR′, —NO 2 , -aryl, -alkylaryl or perhaloalkyl; in which p=0, 1 or 2 and one R3 is in the para position relative to the phenyl ring; or tautomeric forms, enantiomers, diastereoisomers, epimers, or pharmaceutically acceptable salts thereof, with the exception of compounds of formula (II) for which: if X═Y═C, R2=-Cl,