Patent ID: 8598363
Filing Date: 2013-12-03
Classification: C07C,C07D

Abstract:
1. A process for manufacturing 2-[(3,5-difluoro-3′-methoxy-1,1′-biphenyl-4-yl)amino]nicotinic acid, which comprises the steps of: a) providing 3,5-difluoro-3′-methoxybiphenyl-4-amine, b) preparing and isolating an aminium salt of the 3,5-difluoro-3′-methoxybiphenyl-4-amine, and c) further reacting the aminium salt of 3,5-difluoro-3′-methoxybiphenyl-4-amine obtained in b) to obtain 2-[(3,5-difluoro-3′-methoxy-1,1′-biphenyl-4-yl)amino]nicotinic acid.