Patent ID: 9103762
Filing Date: 2015-08-11
Classification: C12Q,G01N

Abstract:
1. A method for detecting a target molecule in a sample by means of a metal wire, said method comprising the steps of: a) providing a detection biomolecule interacting with the target molecule, wherein said detection biomolecule is linked to an enzyme; b) contacting the sample with the detection biomolecule, thereby the detection biomolecule and the target molecule interacting together; c) separating non-interacting and interacting detection biomolecules; d) adding a substrate of the enzyme; e) measuring the conductivity/resistance of the metal wire, thereby detecting the target molecule; wherein the wire is made of a material selected from the group consisting of silver, gold and its alloys; and wherein the reactive species dissolving the wire is selected from among cyanide, cyanohydrin, hypochlorite, hypobromites, iodine, triiodide, and thio-cyanate.