Patent ID: 7582765
Filing Date: 2009-09-01
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A method of treating a pulmonary disease in a mammal, wherein the pulmonary disease is asthma or chronic obstructive pulmonary disease, the method comprising administering to the mammal a therapeutically-effective amount of a compound of formula (IIa): wherein: R R R or a pharmaceutically-acceptable salt or stereoisomer thereof; and a therapeutically-effective amount of a corticosteroid selected from 6α,9α-difluoro-11β-hydroxy-16α-methyl-17α-[(4-methyl-1,3-thiazole-5-carbonyl)oxy]-3-oxo-androsta-1,4-diene-17β-carbothioic acid S-fluoromethyl ester and 6α,9α-difluoro-17α-[(2-furanylcarbonyl)oxy]-11β-hydroxy-16α-methyl-3-oxo-androsta-1,4-diene-17β-carbothioic acid S-fluoromethyl ester.