Patent ID: 6384191
Filing Date: 2002-05-07
Classification: A61K,A61P,C07K,G01N

Abstract:
An isolated and substantially pure polypeptide comprising both IgII and IgII domains from the extracellular region of a naturally occurring human fibroblast growth factor receptor the polypeptide being free of a tyrosine kinase domain, wherein the molecular weight of said polypeptide is less than 85 kD and said extracellular domain is encoded by either a DNA sequence hybridizing under conditions of high stringency including 50% formamide, 5Ã—SSC, 5Ã—Denhardt's solution, 10 mM sodium phosphate, pH 6.5, 100 &mgr;g/ml salmon sperm DNA and at 42Â° C. to the DNA sequence shown in FIGS. 4A-E ora DNA sequence that is a degenerate form of the DNA sequence shown in FIGS. 4A-E.