Patent ID: 7638138
Filing Date: 2009-12-29
Classification: A61K

Abstract:
1. A granular composition for nasal administration, which comprises: a) a powdered pharmaceutical, and b) as a carrier thereof, a substantially water-insoluble crystalline cellulose powder, wherein the pharmaceutical is selected from growth hormone, calcitonin, glucagon, glucagon-like peptide-1, interferon, interleukin, erythropoietin, luteinizing hormone-releasing hormone, somatostatin, vasopressin, oxytocin, enkephalin, adrenocorticotropic hormone, growth hormone-releasing hormone, granulocyte colony formation-stimulating factor, parathyroid hormone, thyroid-stimulating hormone-releasing hormone, angiotensin, prolactin, luteinizing hormone, gastric inhibitory polypeptide (GIP), C-peptide, cyclosporine, and FK-506, and parathyroid hormone (1-34); wherein the crystalline cellulose powder has a sieving particle diameter distribution of: