Patent ID: 7786301
Filing Date: 2010-08-31
Classification: C07C,C07D

Abstract:
1. A method for producing a compound of formula 13A: the method comprising: (i) reacting a compound of formula 7 with a primary amine Compound of Formula 8 or a hydrochloride salt thereof, in the presence of a base to form a compound of formula 9: (ii) treating the compound of formula 9 with a base to remove the protecting group thereby forming a compound of Formula 13A wherein Compound 7 is Compound 7A, Compound 8 is Compound 8A, Compound 9 is Compound 9A and the base in step (i) is sodium bicarbonate, and wherein the reaction is carried out in the presence of N,N-dimethyl acetamide as a solvent: according to the following scheme wherein,