Patent ID: 8476011
Filing Date: 2013-07-02
Classification: C07H,C12N,C40B

Abstract:
1. A method for forming a catalogued nucleic acid library from an initial organism sample comprised of heterogeneous organisms, said method comprising: (a) forming a derived organism sample from the initial heterogeneous organism sample by subjecting all or a part of said initial heterogeneous organism sample to a method of selection, such that proportional representations of the constituents in said derived organism sample are adjusted by subjecting all or a part of said initial heterogeneous organism sample to a method of positive and/or negative selection for at least one organism marker which is a nucleic acid marker characteristic of an organism in the initial organism sample; (b) isolating an initial nucleic acid sample from said derived organism sample of step (a); (c) forming a derived nucleic acid library from said isolated initial nucleic acid sample of step (b), such that the proportional representations of the constituents in said derived nucleic acid library are adjusted to advantage by performing the following steps in any order, and at least one time: thereby forming a catalogued nucleic acid library from the initial organism sample comprised of heterogeneous organisms.