Patent ID: 6281250
Filing Date: 2001-08-28
Classification: C07C

Abstract:
A compound having the general formulaX--O--(CRR.sup.1).sub.n --Y (I)wherein R and R.sup.1 are independently H, OH, halogen, C.sub.1 -C.sub.10 -alkyl, C.sub.1 -C.sub.10 -alkyl halide, C.sub.1 -C.sub.10 -alkoxy, phenoxy or an aryl group; n is 0 or 1; Y is an unsubstituted or substituted aryl; and X is a structure selected from the group consisting of ##STR20##wherein R.sup.2 is H, OH or .dbd.O, R.sup.3 is CH.sub.3 or CH.sub.2 OH, and R.sup.9 is H, or C.sub.1 -C.sub.5 alkyl, or a physiologically acceptable salt thereof, with the provisos that (1) when R and R.sup.1 are both H, X is structure (a), R.sup.2 is H, R.sup.3 is CH.sub.3 and n is 1, then Y is not trimethoxyphenyl or 4-ethynlphenyl; (2) when R.sup.2 is H, R.sup.3 is CH.sub.3 X is structure (a) and n is 0, then Y is not 4-methoxyphenyl; (3) when R and R.sup.1 are both H, X is structure (a), R.sup.2 is H, R.sup.3 is CH.sub.3 and n is 1, then Y is not phenyl; and (4) when X is structure (a), n is 1 and Y is phenyl, then both R and R.sup.1 are not phenyl.