Patent ID: 7604968
Filing Date: 2009-10-20
Classification: A61P,C12N,C12P

Abstract:
1. An E. coli microorganism comprising an exogenous nucleic acid encoding a naturally occurring polypeptide having coumaroyl-CoA-ligase activity and an exogenous nucleic acid encoding a naturally occurring polypeptide having stilbene synthase activity, wherein the polypeptide having coumaroyl-CoA-ligase activity is a plant polypeptide, a Streptomyces polypeptide, a Pseudomonas polypeptide, or a Rhodobacter polypeptide, wherein the polypeptide having stilbene synthase activity is an Arachis hypogaea polypeptide, a Vitis vinifera polypeptide, a Rheum tataricum polypeptide, a Psilotum nudum polypeptide, or a Pinus sylvestris polypeptide, and wherein a culture comprising a plurality of said microorganisms produces and secretes at least 20 mg/L of a flavonoid compound.