Patent ID: 6329344
Filing Date: 2001-12-11
Classification: A61P,C07H

Abstract:
A compound having the structure of Formula I: ##STR10##and its pharmaceutically acceptable salts, esters, enantiomers, diastereomers, N-oxides, amides, or prodrugs, wherein R is C.sub.1 to C.sub.15 alkyl, alkene, straight chain or branched alkyne, aryl, substituted aryl or alkylaryl, R' is SO.sub.2 C.sub.6 H.sub.5, SO.sub.2 C.sub.6 H.sub.4 CH.sub.3 -p, or SO.sub.2 C.sub.6 H.sub.4 Cl-p, phenyl, or C.sub.6 H.sub.4 --R'""-p wherein R'"" is being Cl, NO.sub.2, OCH.sub.3, CH.sub.3, CH.sub.2 COOH, CH.sub.2 COOCH.sub.3, CH.sub.2 COLDVP, CH.sub.2 CODVP, CH.sub.2 COVP, wherein LDVP, DVP and VP represent tripeptide (Leucyl-aspartyl-valyl-prolyl), tripeptide (aspartyl-valyl-prolyl) and (valyl-prolyl), respectively, R"" is H or CH.sub.3, and ({character pullout}) represents epiglucofuranose, epiallofuranose, xylofuranose or ribofuranose configurations.