Patent ID: 8178303
Filing Date: 2012-05-15
Classification: G01N

Abstract:
1. A method for the precipitation of cryoglobulins, comprising the steps of: (a) providing an aqueous cryoglobulin sample; (b) providing a buffer reagent, said buffer reagent comprising sodium chloride in an amount of from 0 to 9 g/L; (c) combining said cryoglobulin sample with said buffer reagent to decrease the ionic strength of the sample and produce a test sample; then (d) chilling said test sample at a temperature less than room temperature for a time of from 15 minutes to one hour to form a cryoglobulin precipitate in said test sample; and then, (e) within a time of not more than one hour, centrifuging said test sample to separate said cryoglobulin precipitate from said test sample, wherein said cryoglobulin precipitate is present in an amount sufficient to quantify and determine its type.