Patent ID: 9044435
Filing Date: 2015-06-02
Classification: A61J,A61K,A61P

Abstract:
1. A controlled release oral solid dosage form comprising particles comprising: (i) hydrocodone or a pharmaceutically acceptable salt thereof; (ii) a gelling agent comprising hydroxypropylmethylcellulose; (iii) ethylcellulose; and (iii) a glyceryl ester of a fatty acid; wherein the particles are overcoated with a controlled release material comprising ethylcellulose; the oral solid dosage form providing a therapeutic effect for at least about 12 hours when orally administered to a human patient and the oral solid dosage form when subjected to tampering by dissolution in from about 0.5 ml to about 10 ml of an aqueous liquid provides a viscosity of at least about 10 cP.