Patent ID: 7619092
Filing Date: 2009-11-17
Classification: A61K,A61P,C07D,C07K

Abstract:
1. A piperidine compound represented by the formulas [I]: wherein Ring A is a benzene ring of the formula: and Ring B is a benzene ring of the formula: wherein A B R (1) a carbonyl group is substituted by a group selected from an optionally substituted monocyclic heterocyclic group selected from morpholino group, piperazinyl group, imidazolyl group, thiomorpholino group, piperidino group, furyl group, tetrahydrothiazolinyl group or pirrolidinyl group (the substitutent of the monocyclic hetrocyclic group is an alkyl group optionally substituted by hydroxyl group, an alkoxycarbonyl group, a carboxyl group, a hydroxyalkylaminocarbonyl group, an alkoxyalkylaminocarbonyl group, an alkylthioalkylaminocarbonyl group, an alkylsulfinylalkylaminocarbonyl group, an alkylsulfonylalkylaminocarbonyl group or a morpholino group; an oxo group; or hydroxyl group.), (2) a sulfinyl group is substituted by a group selected from (3) a sulfonyl group is substituted by a group selected from (4) an alkyl group is substituted by a group selected from an optionally substituted monocyclic heterocyclic group is selected from pyridyl group, piperidinyl group, morpholino group, isoxazolyl group, triazolyl group, tetrazolyl group and pirrolidinyl group (the substituent of the monocyclic hetrocyclic group is an alkyl group or phenyl group), R an amino group optionally substituted by an alkyl group, an alkyl group optionally substituted by an alkoxy group, a carbonyl group substituted by hydroxyl group, an nalkoxy group or an alkylamino group, or a halogen atom, Z represents oxygen atom or a group represented by —N(R R