Patent ID: 6565814
Filing Date: 2003-05-20
Classification: B01L

Abstract:
A closure structure for a vacuum specimen collection container which can be detachably fitted in an open end of a specimen collection tube in an airtight manner to maintain a vacuum condition inside the specimen collection tube, the closure structure comprising:a grip section including a tubular side wall portion for providing a finger grip, a partition portion extending inward from the side wall portion and having a through-hole through which a specimen collection needle cannula can be passed into the specimen collection tube; a rubber elastic, needle cannula penetrating portion provided to fill up the through-hole in the grip section and having the capability to reseal a hole if left after the needle cannula is retracted; a rubber elastic fitting portion depending from the needle cannula penetrating portion or the grip section and configured to follow an inner surface profile at the open end of the specimen collection tube to thereby contact fit therein in an airtight manner; said grip section having a higher rigidity relative to the needle cannula penetrating portion and the fitting portion; and said tubular side wall of the grip section being provided on its inner side with at least one raised or recessed portion to prevent kickback; wherein below-specified parameters satisfy the following relationship (1): (So-Sd)Ã—P1T1+SdÃ—P2T2&LessFullEqual;10Ã—10-10where T1 (mm) is a wall thickness of the partition portion of the grip section, P1 (ml/cm2Â·mmâˆ’1Â·secÂ·cm Hg) is an oxygen permeability coefficient of the partition at 25Â° C., T2 (mm) is a wall thickness of the needle cannula penetrating portion in a needle penetrating direction, P2 (ml/cm2Â·mmâˆ’1Â·secÂ·cmHg) is an oxygen permeability coefficient of the needle cannula penetrating portion at 25Â° C., Sd (cm2) is a minimum cross-sectional area of the through-hole in the grip section and So (cm2) is an open area at the open end of the specimen collection tube.