Patent ID: 6331313
Filing Date: 2001-12-18
Classification: A61F,A61K,A61P

Abstract:
A biocompatible implantable ocular controlled release drug delivery device sized for implantation within an eye for continuously delivering a drug within the eye for a period of at least several weeks comprising a polymeric outer layer that is substantially impermeable to the drug and ocular fluids covering a core comprising a drug that dissolves in ocular fluids, wherein said outer layer has one or more orifices through which ocular fluids may pass to contact the core and dissolve drug and dissolved drug may pass to the exterior of the device, said orifices in total having an area less than one percent of the total surface area of said device, and wherein the rate of release of the drug is determined solely by the composition of the core and the total surface area of the one or more orifices relative to the total surface area of said device.