Patent ID: 8652512
Filing Date: 2014-02-18
Classification: A61K

Abstract:
1. A method of pulmonary administration comprising administering to a subject in need thereof via inhalation via a nebulizer a liposomal formulation comprising: a) liposomes, that comprise as a first component dipalmitoylphosphatdylcholine (DPPC) lipids, as a second component cholesterol (CH) lipids, and a third component selected from the group consisting of dimyristoylphosphatidylcholine (DMPC) lipids, sphingomyelin (SM) lipids and polyethylene glycol (PEG) and PEG derivatives and b) an active agent encapsulated inside the liposomes, wherein a molar ratio between the DPPC lipids and the CH lipids ranges from 7:3 to 7:4 and wherein upon said administering 50-80% of the liposomes remain intact.