Patent ID: 8071538
Filing Date: 2011-12-06
Classification: A61K,A61P,C07K,C12N,G01N

Abstract:
1. A method of increasing lean muscle mass in a subject comprising administering a pharmaceutical composition to the subject, wherein the pharmaceutical composition comprises a therapeutically effective amount of a myostatin binding agent wherein the myostatin binding agent has the structure: (X wherein F 1 is a vehicle; and X 1 and X 2 are each independently selected from -(L -(L -(L and -(L wherein P wherein one or more of the peptides capable of binding myostatin comprise the amino acid sequence Cb 1 b 2 Wb 3 WMCPP (SEQ ID NO: 353), wherein b b b and wherein the peptide is between 10 and 50 amino acids in length, and physiologically acceptable salts thereof.