Patent ID: 7442717
Filing Date: 2008-10-28
Classification: A61P,C07D

Abstract:
1. A compound of formula I, or a pharmaceutically acceptable salt or trifluoroacetic acid salt of said compound: where: R1 and R2 together with the two carbon atoms to which they are bonded, form a five-, six-, seven- or eight-membered carbon ring comprising one or two double bonds, said ring being substituted by 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12 fluorine atoms and further substituted by 0, 1, or 2 radicals selected from the group consisting of OH, NR9R10, alkyl with 1, 2, 3 or 4 carbon atoms, CN, CF R3, R4, R5, R6 and R7 are independently selected from the group consisting of hydrogen, F, Cl, Br, I, alkyl with 1, 2, 3 or 4 carbon atoms and substituted by 0, 1, 2, 3, 4, 5, 6, 7, 8 or 9 fluorine atoms, and alkoxy with 1, 2, 3 or 4 carbon atoms and substituted by 0, 1, 2, 3, 4, 5, 6, 7, 8 or 9 fluorine atoms, provided that R3 and R7 are not both simultaneously hydrogen; R8 is selected from the group consisting of H, alkyl with 1, 2, 3 or 4 carbon atoms and substituted by 0, 1, 2, 3, 4, 5, 6, 7, 8 or 9 fluorine atoms, and cycloalkyl with 3, 4 or 5 carbon atoms and substituted by 0, 1, 2, 3, 4, 5, 6, 7, 8 or 9 fluorine atoms.