Patent ID: 6071528
Filing Date: 2000-06-06
Classification: A61K

Abstract:
An adhesive antimicrobial dental composition comprising:at least one alkyl methacrylate having at least one oxyphosphorus group having a formula selected from the group consisting of ##STR2## wherein R is an alkyl; at least one additional monomer which is at least one of an alkyl methacrylate, an alkyl hydroxy methacrylate, an alkyl amino methacrylate, or bisphenol-A-diglycidyl dimethacrylate;at least one polymerization photoinitiator which only initiates polymerization of the alkyl methacrylate having at least one oxyphosphorus group and the at least one additional monomer upon irradiating the dental composition with radiant energy, wherein the photoinitiator is at least one of camphorquinone, benzoin methyl ether, 2-hydroxy-2-methyl-1-phenyl-1-propanone, diphenyl-2,4,6-trimethylbenzoyl phosphine oxide, benzoin ethyl ether, benzophenone, or 9,10-anthroquinone;a filler which is at least one of silicon dioxide, titanium dioxide, barium sulfate, strontium sulfate, barium chloride, strontium chloride, or calcium phosphate tribasic; andat least one antimicrobial agent in an antimicrobially effective amount, wherein the antimicrobial agent is at least one of an antibiotic, 1,1'-hexamethylene bis(5(p-chlorophenyl)biguanide), cetyl pyridinium chloride, benzalkonium chloride, cetyl pyridinium bromide, an alkali metal hydroxide, an alkaline earth metal hydroxide, or an alkaline earth metal oxide included in a form that permits formation of an alkaline earth metal hydroxide when the dental composition is exposed to water,wherein the dental composition is capable of being placed on a treatment area of a dental substrate for in situ polymerization of the alkyl methyacrylate by irradiating the dental composition with radiant energy for adherence to the dental substrate.