Patent ID: 6294564
Filing Date: 2001-09-25
Classification: A61P,C07D

Abstract:
A compound of the formula I ##STR3##in whichY is O (oxygen) or NH,R1 is 1-4C-alkoxy, 3-7C-cycloalkoxy, 3-7C-cycloalkylmethoxy, benzyloxy or completely or predominantly fluorine-substituted 1-4C-alkoxy,R2 is hydrogen or 1-4C-alkyl andR3 is hydrogen or 1-4C-alkyl,or in whichR2 and R3, together and including the two carbon atoms to which they are attached, are a spiro-linked 5-, 6- or 7-membered hydrocarbon ring which, if desired, is interrupted by an oxygen atom,R4 is C(O)R5, C(O)R6,--C.sub.n H.sub.2n --C(O)R5 or --C.sub.n H.sub.2n --C(O)R6, whereR5 is hydroxyl, 1-7C-alkoxy, 3-7C-cycloalkoxy, 3-7C-cycloalkylmethoxy, H.sub.2 N--C.sub.m H.sub.2m --O-- or R51 (R52)N--C.sub.p H.sub.2p --O--, whereR51 is hydrogen, 1-7C-alkyl, 3-7C-cycloalkyl or 3-7C-cycloalkylmethyl andR52 is 1-7C-alkyl, 3-7C-cycloalkyl or 3-7C-cycloalkylmethyl, or whereR51 and R52, together and including the nitrogen atom to which both are attached, are a 5-, 6- or 7-membered hydrocarbon ring which, if desired, is additionally interrupted by a group --N(R7)-- or an oxygen atom,R6 is N(R61)R62, where R61 and R62 independently of one another are hydrogen, 1-7C-alkyl, 3-7C-cycloalkyl or 3-7C-cycloalkylmethyl,R7 is hydrogen or 1-4C-alkyl,m is 2,3 or 4,n is 1,2,3 or 4,p is 1,2,3 or 4,and the salts of these compounds.