Patent ID: 7815936
Filing Date: 2010-10-19
Classification: A61K,B01J

Abstract:
1. A pharmaceutical composition comprising granular pyrogenically produced silicon dioxide, having void volumes, and at least one pharmaceutical active constituent, wherein the granular silicon dioxide has meso- and macropores, a mean grain diameter of 10 to 120 μm and a BET surface of 40 to 400 m 2 /g, determination according to DIN 66 131 using nitrogen, wherein the mesopores account for 10 to 80% of the total volume and the particle size distribution of the granular material is 80 vol. % greater than 8 μm and 80% less than 96 μm and the proportion of the pores less than 5 μm be at most 5% referred to the total pore volume.