Patent ID: 6197584
Filing Date: 2001-03-06
Classification: A61K,A61P,C12N

Abstract:
An antisense oligonucleotide 8 to 30 nucleobases in length targeted to nucleotides 73 through 122 or nucleotides 152 through 240 or nucleotides 250 through 309 or nucleotides 318 through 381 or nucleotides 391 through 643 or nucleotides 657 through 696 or nucleotides 703 through 720 or nucleotides 729 through 746 or nucleotides 750 through 827 or nucleotides 834 through 851 or nucleotides 861 through 878 of a coding region, nucleotides 910 through 927 or nucleotides 954 through 971 or nucleotides 976 through 993 of a 3'UTR, or nucleotides 18 through 43 of a 5'UTR of a nucleic acid molecule encoding human CD40 SEQ ID NO:85, wherein said antisense oligonucleotide inhibits the expression of human CD40.