Patent ID: 6124118
Filing Date: 2000-09-26
Classification: A61K,C07K,C12N

Abstract:
A recombinant DNA molecule encoding a receptor recognition factor (RRF), wherein the recombinant DNA molecule hybridizes under standard hybridization conditions of 5.times. SSC and 65.degree. C. to a nucleic acid complementary to a DNA sequence selected from the group consisting of SEQ ID NO: 1, SEQ ID NO:3, SEQ ID NO:5, SEQ ID NO:7, SEQ ID NO:9, and SEQ ID NO: 11; wherein the RRF has the following characteristics:a) it is cytoplasmic in origin;b) it is activated by tyrosine phosphorylation; andc) upon activation the RRF is translocated to the nucleus of a target cell.