Patent ID: 8895559
Filing Date: 2014-11-25
Classification: A61P,C07D

Abstract:
1. A compound, which is one of the following compounds A1 1-Methyl-1H-imidazole-4-sulfonic acid [3-(6-methoxybenzo-1,3-dioxo-4-ylamino)quinoxalin-2-yl] amide; A2 4-Cyano-N{3-[2(3-dimethylaminopropyl)-3,5-dimethoxyphenylaminol]-quinoxalin-2-yl}benzene sulfonamide; A3 4-Cyano-N-(3-{2-[3-(1,1-dioxo-1-lambda*6*-thiomorpholin-4-yl)propyl]-3,5-dimethoxyphenylamino}quinoxalin-2-yl)benzenesulfonamide; A4 1-Methyl-1H-imidazole-4-sulfonic acid (3-{2-[3-(1, 1-dioxo-1-lambda*6*-thiomorpholin-4-yl)propyl]-3,5-dimethoxyphenylamino}quinoxalin-2-yl) amide; A5 1-Methyl-1H-imidazole-4-sulfonic acid[3-(2-hydroxymethyl-5-methoxy-2,3-dihydrobenzofuran-7-ylamino)quinoxalin-2-yl] amide; A6 4-Cyano-N-{3-[2-(4-hydroxybutyl)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}-benzenesulfonamide; A7 1-Methyl-1H-imidazole-4-sulfonic acid {3-[2-(4-hydroxybutyl)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A8 4-[3-(7-Methoxy-2,3-dihydrobenzo-1,4-dioxin-5-ylamino)quinoxalin-2-ylsulfamoyl]-N,N-dimethylbenzamide; A9 5-Methoxy-7-[3-(1-methyl- 1H-imidazole-4-sulfonylamino)quinoxalin-2-ylamino]benzofuran-2-carboxylic acid dimethyl amide; A10 1-Methyl-1H-imidazole-4-sulfonic acid [3-(7-methoxy-2,3-dihydrobenzo-1,4-dioxin-5-ylamino)quinoxalin-2-yl] amide; A11 1-Methyl-1H-imidazole-4-sulfonic acid [3-(2,5-dimethoxy-3-methyl-phenylamino)quinoxalin-2-yl] amide; A12 4-[3-(2,5-Dimethoxy-3-methylphenylamino)quinoxalin-2-ylsulfamoyl]-N,N-dimethylbenzamide; A13 4-[3-(2-Ethyl-3,5-dimethoxyphenylamino)quinoxalin-2-ylsulfamoyl]-N,N-dimethylbenzamide; A14 1-Methyl-1H-imidazole-4-sulfonic acid [3-(2-ethyl-3,5-dimethoxyphenylamino)-quinoxalin-2-yl] amide; A15 4-[3-(5-Methoxybenzofuran-7-ylamino)quinoxalin-2-ylsulfamoyl]-N,N-dimethyl-benzamide; A16 1-Methyl-1H-imidazole-4-sulfonic acid [3-(5-methoxybenzofuran-7-ylamino)-quinoxalin-2-yl] amide; A17 1-Methyl-1H-imidazole-4-sulfonic acid [3-(3-ethyl-2,5-dimethoxyphenylamino)-quinoxalin-2-yl] amide; A18 4-[3-(3-Ethyl-2,5-dimethoxyphenylamino)quinoxalin-2-ylsulfamoyl]-N,N-dimethylbenzamide; A19 1-Methyl-1H-imidazole-4-sulfonic acid [3-(2-bromo-3,5-dimethoxyphenylamino)quinoxalin-2-yl] amide; A20 1-Methyl-1H-imidazole-4-sulfonic acid [3-(2-chloro-3,5-dimethoxyphenylamino)quinoxalin-2-yl] amide; A21 Pyridine-4-sulfonic acid {3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]-quinoxalin-2-yl} amide; A22 Thiazole-5-sulfonic acid {3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]-quinoxalin-2-yl} amide; A23 1-(2-Dimethylaminoethyl)-1H-pyrazole-4-sulfonic acid {3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A24 1-Methyl-1H-pyrazole-3-sulfonic acid {3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A25 N-{3-[2-(3-Hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}-methanesulfonamide; A26 N-{3[2-(3-Hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}-2-methoxybenzenesulfonamide; A27 2 -(4 {3-[2-(3-Hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-ylsulfamoyl}pyrazol-1-yl)-N,N-dimethylacetamide; A28 2-Dimethylaminomethyl-1-methyl-1H-imidazole-4-sulfonic acid {3-[2-(3-hydroxybutoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A29 1-Difluoromethyl-1H-pyrazole-4-sulfonic acid {3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A30 N-{3-[2-(3-Hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}-benzenesulfonamide; A31 2-Dimethylaminomethyl-1-methyl-1H-imidazole-4-sulfonic acid [3-(2,3,5-trimethoxyphenylamino)quinoxalin-2-yl] amide; A32 1-Methyl-1H-imidazole-4-sulfonic acid {3-[2-(3-hydroxy-2-methylpropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A33 2-Dimethylaminomethyl-1-methyl-1H-imidazole-4-sulfonic acid {3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A34 Ethyl (4-{3[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-ylsulfamoyl}phenyl)carbamate; A35 1,1-Dioxotetrahydro-1-lambda*6*-thiophene-3-sulfonic acid {3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A36 3-Methanesulfonylpropan-1-sulfonic acid {3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A38 4-Dimethylaminomethyl-N-{3[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}benzenesulfonamide; A39 C,C,C-Trifluoro-N-{3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]-quinoxalin-2-yl}methanesulfonamide; A40 C,C,C-Trifluoro-N-[3-(2,3,5-trimethoxyphenylamino)quinoxalin-2-yl]methanesulfonamide; A41 5-Cyanothiophene-2-sulfonic acid {3-[2-(2-methanesulfonylethoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A42 1-Methyl-1H-imidazole-4-sulfonic acid {3-[2-(3-hydroxybutoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A43 1-Methyl-1H-pyrazole-4-sulfonic acid {3-[2-(3-hydroxybutoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A44 1-Methyl-1H-pyrazole-4-sulfonic acid {3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A45 4-Cyano-N{3-[2-(3-hydroxybutoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}benzenesulfonamide; A46 2-Cyano-N-{3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}benzenesulfonamide; A47 1-Methyl-1H-imidazole-4-sulfonic acid (3-{3,5-dimethoxy-2-[2-(2-methoxy-ethoxy)ethoxy]phenylamino}quinoxalin-2-yl) amide; A48 4-Cyano-N-(3-{3,5-dimethoxy-2-[2-(2-methoxyethoxy)ethoxy]phenylamino}-quinoxalin-2-yl)benzenesulfonamide; A49 C,C,C-Trifluoro-N-(3-{2-[2-(2-hydroxyethoxy)ethoxy]-3,5-dimethoxyphenylamino}quinoxalin-2-yl)methanesulfonamide; A50 N-(4-{3-[2-(3-Hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-ylsulfamoyl}phenyl)acetamide; A51 5-Cyanothiophene-2-sulfonic acid {3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A52 1-Methyl-1H-imidazole-4-sulfonic acid {3-[2-(2-methanesulfinylethoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A53 4-Fluoro-N-(3-{2-[2-(2-hydroxyethoxy)ethoxy]-3,5-dimethoxyphenylamino}-quinoxalin-2-yl)benzenesulfonamide; A54 1-Methyl-1H-imidazole-4-sulfonic acid {3-[3,5-dimethoxy-2-(2-morpholin-4-yl-ethoxy)phenylamino]quinoxalin-2-yl} amide; A55 1-Methyl-1H-imidazole-4-sulfonic acid {3-[2-(2-methanesulfonylethoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A56 Propane-1-sulfonic acid (3-{2-[2-(2-hydroxyethoxy)ethoxy]-3,5-dimethoxyphenylamino}quinoxalin-2-yl) amide; A57 4-Dimethylaminomethyl-N-(3-{2-[2-(2-hydroxyethoxy)ethoxy]-3,5-dimethoxyphenylamino}quinoxalin-2-yl)benzenesulfonamide; A58 -N-(3-{2-[2-(2-Hydroxyethoxy)ethoxy]-3,5-dimethoxyphenylamino}quinoxalin-2-yl)benzenesulfonamide; A59 5-Cyanothiophene-2-sulfonic acid (3-{2-[2-(2-hydroxyethoxy)ethoxy]-3,5-dimethoxyphenylamino}quinoxalin-2-yl) amide; A60 Thiophene-2-sulfonic acid [3-(2-{2-[(2-hydroxyethyl)methylamino]ethoxy}-3,5-dimethoxyphenylamino)quinoxalin-2-yl] amide; A61 N-(3-{2-[2-(2-Hydroxyethoxy)ethoxy]-3,5-dimethoxyphenylamino}quinoxalin-2-yl)-4-methoxybenzenesulfonamide; A62 N-[4-(3-{2-[2-(2-Hydroxyethoxy)ethoxy]-3,5-dimethoxyphenylamino}-quinoxalin-2-ylsulfamoyl)phenyll]acetamide; A63 3-Cyano-N-(3-{2-[2-(2-hydroxyethoxy)ethoxy]-3,5-dimethoxyphenylamino}-quinoxalin-2-yl)benzenesulfonamide; A64 Thiophene-2-sulfonic acid (3-{2-[2-(2-hydroxyethoxy)ethoxy]-3,5-dimethoxy-phenylamino}quinoxalin-2-yl) amide; A65 Pyridine-3-sulfonic acid (3-{2-[2-(2-hydroxyethoxy)ethoxy]-3,5-dimethoxy-phenylamino}quinoxalin-2-yl) amide; A66 Thiophene-2-sulfonic acid {3[2-(2-hydroxyethoxy)-3,5-dimethoxyphenylamino]-quinoxalin-2-yl} amide; A67 Pyridine-3-sulfonic acid (3-{2-[2-(2-hydroxyethanesulfonyl)ethoxy]-3,5-dimethoxyphenylamino}quinoxalin-2-yl) amide; A68 Pyridine-3-sulfonic acid [3-(2-{2-[(2-hydroxyethyl)-methylamino]ethoxy}-3,5-dimethoxyphenylamino)quinoxalin-2-yl] amide; A69 4 -(3-{2-[2-(2-Hydroxyethoxy)ethoxy]-3,5-dimethoxyphenylamino}quinoxalin-2-ylsulfamoyl)-N,N-dimethylbenzamide; A70 4-Cyano-N-{3-[3,5-dimethoxy-2-(2-morpholin-4-ylethoxy)phenylamino]-quinoxalin-2-yl}benzenesulfonamide; A71 3,4-Difluoro-N-{3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]-quinoxalin-2-yl}benzenesulfonamide; A72 4-Cyano-N-(3-{2-[2-(2-hydroxyethanesulfinyl)ethoxy]-3,5-dimethoxyphenylamino}quinoxalin-2-yl)benzenesulfonamide; A73 3,4-Difluoro-N-(3-{2-[2-(2-hydroxyethoxy)ethoxy]-3,5-dimethoxyphenylamino}-quinoxalin-2-yl)benzenesulfonamide; A74 4-Cyano-N-{3-[2-(2,3-dihydroxypropoxy)-3,5-dimethoxyphenylamino]-quinoxalin-2-yl}benzenesulfonamide; A75 1-Methyl-1H-imidazole-4-sulfonic acid {3-[2-(2,3-dihydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A76 4-Cyano-N-(3-{2-[2-(2-hydroxyethanesulfonyl)ethoxy]-3,5-dimethoxyphenylamino}quinoxalin-2-yl)benzenesulfonamide; A77 1 -Methyl-1H-imidazole-4-sulfonic acid (3-{2-[2-(2-hydroxyethanesulfonyl)-ethoxy]-3,5-dimethoxyphenylamino}quinoxalin-2-yl) amide; A78 4-Cyano-N-[3-(2-{2-[(2-hydroxyethyl)methylamino]ethoxy}-3,5-dimethoxyphenylamino)quinoxalin-2-yl]benzenesulfonamide; A79 Pyridine-3-sulfonic acid {3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]-quinoxalin-2-yl} amide; A80 4-Cyano-N-(3-{2-[2-(2-hydroxyethoxy)ethoxy]-3,5-dimethoxyphenylamino}-quinoxalin-2-yl)benzenesulfonamide; A81 1-Methyl-1H-imidazole-4-sulfonic acid (3-{2-[2-(2-hydroxyethoxy)ethoxy]-3,5-dimethoxyphenylamino}quinoxalin-2-yl) amide; A82 4-Cyano-N-{3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}benzenesulfonamide; A83 1-Methyl-1H-imidazole-4-sulfonic acid [3-(5-difluoromethoxy-2,3-dimethoxyphenylamino)quinoxalin-2-yl] amide; A84 4-Cyano-N-[3-(5-difluoromethoxy-2,3-dimethoxyphenylamino)quinoxalin-2-yl]-benzenesulfonamide; A85 4-[3-(5-Difluoromethoxy-2,3-dimethoxyphenylamino)quinoxalin-2-ylsulfamoyl]-N,N-dimethylbenzamide; A86 1-Methyl-1H-imidazole-4-sulfonic acid {3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A87 4-{3-[2-(3-Hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-ylsulfamoyl}-N,N-dimethylbenzamide; A88 4-{3-[2-(2-Hydroxyethoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-ylsulfamoyl}-N,N-dimethylbenzamide; A89 1-Methyl-1H-imidazole-4-sulfonic acid {3-[2-(2-hydroxyethoxy)-3,5-dimethoxy-phenylamino]quinoxalin-2-yl} amide; A90 N,N-Dimethyl-4-[3-(2,3,5-trimethoxyphenylamino)quinoxalin-2-ylsulfamoyl]-benzamide; A91 4-Cyano-N-[3-(2,3,5-trimethoxyphenylamino)quinoxalin-2-yl]-benzenesulfonamide; A92 1-Methyl-1H-imidazole-4-sulfonic acid [3-(2,3,5-trimethoxyphenylamino)-quinoxalin-2-yl] amide; A93 N-{3-[2-(3-Hydroxybutoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}-methanesulfonamide; A94 2-Dimethylaminomethyl-1-methyl-1H-imidazole-4-sulfonic acid {3-[2-(4-hydroxybutyl)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A95 4-{3-[2-(3-Hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-ylsulfamoyl}-N-(2,2,2-trifluoroethyl)benzamide; A96 2-Cyanoethanesulfonic acid {3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A97 3-{3-[2-(3-Hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-ylsulfamoyl}-N,N-dimethylbenzamide; A98 4-(3,3-Difluoroazetidine-1-carbonyl)-N-{3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}benzenesulfonamide; A99 N-{3-[2-(3-Hydroxybutoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}methanesulfonamide; A100 1-Methyl-1H-pyrazole-3-sulfonic acid {3-[2-(3-hydroxybutoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A101 Thiazole-5-sulfonic acid {3-[2-(3-hydroxybutoxy)-3,5-dimethoxyphenylamino]-quinoxalin-2-yl} amide; A102 4-(Azetidine-1-carbonyl)-N-{3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}benzenesulfonamide; A103 1-Difluoromethyl-1H-pyrazole-4-sulfonic acid {3-[2-(3-hydroxybutoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A 104 A105 3-{3-[2-(3-Hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-ylsulfamoyl}-N-(2,2,2-trifluoroethyl)benzamide; A106 4-Aminomethyl-N-{3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]-quinoxalin-2-yl}benzenesulfonamide; A107 3-(3,3-Difluoroazetidine-1-carbonyl)-N-{3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}benzenesulfonamide; A108 3-(Azetidine-1-carbonyl)-N-{3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}benzenesulfonamide; A109 3-Dimethylaminomethyl-N-{3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}benzenesulfonamide; A110 4-(3,3-Difluoroazetidin-1-ylmethyl)-N-{3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}benzenesulfonamide; A111 4-Azetidin-1-ylmethyl-N-{3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}benzenesulfonamide; A112 1-Methyl-1H-pyrazole-3-sulfonic acid (3-{2-[2-(2-hydroxyethoxy)ethoxy]-3,5-dimethoxyphenylamino}quinoxalin-2-yl) amide; A113 2-Dimethylaminomethyl-1-methyl-1H-imidazole-4-sulfonic acid {3-[2(4-hydroxybutoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A114 C,C-Difluoro-N-{3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]-quinoxalin-2-yl}methanesulfonamide; A115 C,C-Difluoro-N-{3-[2-(3-hydroxybutoxy)-3,5-dimethoxyphenylamino]-quinoxalin-2-yl}-methanesulfonamide; A116 3-Azetidin-1-ylmethyl-N-{3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl}benzenesulfonamide; A117 1-Methyl-1H-pyrazole-3-sulfonic acid {3-[2-(4-hydroxybutyl)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A118 2,2-Difluoro-2-(3-{3-[2-(3-hydroxybutoxy)-3,5-dimethoxyphenylamino]-quinoxalin-2-ylsulfamoyl}pyrazol-1-yl)-N,N-dimethylacetamide; A119 2,2-Difluoro-2-(3-{3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]-quinoxalin-2-ylsulfamoyl}pyrazol-1-yl)-N,N-dimethylacetamide; A120 2-(3-{3-[2-(3-Hydroxybutoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-ylsulfamoyl}pyrazol-1-yl)-N,N-dimethylacetamide; A121 1-Methyl-1H-pyrazole-3-sulfonic acid [3-(2,3,5-trimethoxyphenylamino)-quinoxalin-2-yl] amide; A122 2-(3-{3-[2-(3-Hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-ylsulfamoyl}pyrazol-1-yl)-N,N-dimethylacetamide; A123 2-Diethylaminomethyl-1-methyl-1H-imidazole-4-sulfonic acid {3-[2-(3-hydroxy-butoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A124 1-Methyl-1H-imidazole-4-sulfonic acid [3-(2-hydroxymethyl-7-methoxy-2,3-dihydrobenzo-1,4-dioxin-5-ylamino)quinoxalin-2-yl] amide; A125 1-Methyl-1H-pyrazole-3-sulfonic acid {3-[2-(3-hydroxy-3-methylbutoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A126 2-Diethylaminomethyl-1-methyl-1H-imidazole-4-sulfonic acid {3-[2-(3-hydroxy-propoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A127 1-Methyl-1H-imidazole-4-sulfonic acid [3-(3-hydroxymethyl-7-methoxy-2,3-dihydrobenzo-1,4-dioxin-5-ylamino)quinoxalin-2-yl] amide; A128 2-Dimethylaminomethyl-1-methyl-1H-imidazole-4-sulfonic acid {3-[2(3-hydroxy-3-methylbutoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A129 1-(2-Dimethylaminoethyl)-1H-pyrazole-3-sulfonic acid {3-[2-(3-hydroxybutoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A130 1-(2-Dimethylaminoethyl)-1H-pyrazole-3-sulfonic acid {3-[2-(3-hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-yl} amide; A131 N,N-Dimethyl-2-{3-[3-(2,3,5-trimethoxyphenylamino)quinoxalin-2-ylsulfamoyl]-pyrazol-1-yl}acetamide; or A132 N-(4-{3-[2-(3-Hydroxypropoxy)-3,5-dimethoxyphenylamino]quinoxalin-2-ylsulfamoyl}benzyl)acetamide; or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof.