Patent ID: 6048866
Filing Date: 2000-04-11
Classification: A61P,C07D

Abstract:
A compound which is selected from the group consisting of:4-(3-methoxyphenylsulphanyl)-N-{[3,5-dimethyl-4-(2-pyrrolidin-1-yl)-ethoxy] phenyl}-2-pyrimidineamine;4-(3-Carboxyphenylsulphanyl)-N-{[3,5-dimethyl-4-(2-pyrrolidin-1-yl)ethoxy]p henyl}-2-pyrimidineamine;N-[4,5-Dimethoxy-3-(2-pyrrolidin-1-ylethoxy)phenyl]-4-(3-methoxyphenyl-sulp hanyl)-2-pyrimdineamine;4-(3-Methoxyphenylsulphanyl)-N-{[4-methoxy-[3-(2-pyrrolidin-1-yl)ethoxy]phe nyl}-2-pyrimidineamine;N-{3,5-Dimethoxy-4-[2-pyrrolidin-1-yl)ethoxy]phenyl}-4-(3-methoxyphenyl-sul phanyl)-2-pyrimdineamine;N-{[4,5-Dimethoxy-3-(2-pyrrolidin-1-yl)ethoxy]phenyl}-4-(4-fluorophenyl-sul phanyl)pyrimidine-2-amine;4-(3-Bromophenylsulphanyl)-N-[4,5-dimethoxy-3-(2-pyrrolidin-1-ylethoxy]phen yl]-2-pyrimidineamine;N-{3,5-Dichloro-4-[2-pyrrolidin-1-yl)ethoxy]phenyl}-4-(3,5-dimethylphenyl-s ulphanyl)-2-pyrimdineamine; and the salts and hydrates thereof.