Patent ID: 7968751
Filing Date: 2011-06-28
Classification: C07B,C07C,C07D,C07H

Abstract:
1. A method of fluorination which comprises fluorinating a substrate by bringing the substrate and a fluorinating agent into reaction with each other under irradiation with at least one of microwave and electromagnetic wave having a wavelength around a microwave region; wherein the substrate is selected from the group consisting of monohydroxy alcohol; polyol having a plurality of hydroxyl groups; thiol; a compound having carbonyl group or carboxyl group; an aromatic compound exhibiting an increased nucleophilicity due to the presence of an electron-attracting group; aromatic diazonium salt; oligosaccharide and polysaccharide; hydrocarbon having a cage shape; and epoxide; and the fluorinating agent is represented by general formula (I): wherein Y represents nitrogen atom or phosphorus atom, R 0 , R 1 and R 2 represent hydrogen atom or an alkyl or aryl group which may have substituents, the atom and the groups represented by R 0 , R 1 and R 2 may be a same with or different from each other atom, and two or three of the groups represented by R 0 , R 1 and R 2 may be bonded to each other to form a ring.