Patent ID: 7863416
Filing Date: 2011-01-04
Classification: A61K,C07K

Abstract:
1. A hexapeptide of the formula: Arg-Xaa-Tyr-Arg-Trp-Arg (SEQ ID NO: 17), wherein the hexapeptide binds with the ORL-1 receptor, wherein Xaa is selected from the group consisting of natural amino acids, D-amino acids, non-natural amino acids, and modified natural amino acids, the natural amino acids consisting of Gly, Ala, Val, Leu, Ile, Met, Pro, Phe, Trp, Ser, Thr, Asn, Gln, Cys, Lys, Arg, His, Asp, and Glu, the modified natural amino acids excluding Phe (4-Me), Phe (4-COOH), Phe (4-NO