Patent ID: 7115625
Filing Date: 2006-10-03
Classification: A61K,A61P

Abstract:
1. A method of treating congestive heart failure in a mammal comprising: concurrently administering to the mammal a therapeutically effective amount for treating congestive heart failure of a combination of a compound selected from the group consisting of pyridoxal-5′-phosphate, pyridoxal, pyridoxamine, a 3-acylated pyridoxal analogue, a pharmaceutically acceptable acid addition salt thereof, and a mixture thereof, and a therapeutic cardiovascular compound selected from the group consisting of an angiotensin converting enzyme inhibitor, an angiotensin II receptor antagonist, a vasodilator, a diuretic, an α-adrenergic receptor antagonist, and a mixture thereof, wherein the 3-acylated pyridoxal analogue is a compound of the formula wherein R R