Patent ID: 7074835
Filing Date: 2006-07-11
Classification: A61K,A61P,C07C

Abstract:
1. A compound of formula (I): in which A is a C alkylene group with a chain length between NH and N(O)R′R″ of at least 2 carbon atoms and R′ and R″ are each separately selected from C 1-4 alkyl groups and C 2-4 hydroxyalkyl and C 2-4 dihydroxyalkyl groups in which the carbon atom attached to the nitrogen atom does not carry a hydroxy group and no carbon atom is substituted by two hydroxy groups, or R′ and R″ together are a C 2-6 alkylene group which with the nitrogen atom to which R′ and R″ are attached forms a heterocyclic group having 3 to 7 atoms in the ring, wherein the compound is formulated so that upon dissolution in aqueous solution the pH of the solution is in the range of 5 to 9.