Patent ID: 6566473
Filing Date: 2003-05-20
Classification: A61K,A61Q,C08F

Abstract:
A non-aqueous, heterogeneous polymerization process which provides a cosmetically or pharmaceutically-acceptable polymer swollen with an oil composition which comprises: polymerizing, by weight, about 5-70% of a vinyl amide monomer, optionally with a comonomer, in a total amount of about 30-95% of an oil as solvent and a water-soluble cosolvent, and a free radical initiator, optionally in the presence of a crosslinking agent and/or an oil soluble surfactant, with agitation, under an inert gas, at about 40-150Â° C., wherein said amount of the oil and cosolvent is sufficient to keep the resultant vinyl lactam polymer in a stirrable state until the end of the polymerization and wherein the vinyl monomer and optional crosslinking agent are fed into the reactor charged with said oil and cosolvent and free radical initiator continuously over a period of about 3-6 hours at a rate such that substantially no free monomer is present during the polymerization.