Patent ID: 6235912
Filing Date: 2001-05-22
Classification: C07C,C07D,Y02P

Abstract:
A sphingosine analogue represented by the following general formula (I): ##STR11##In the formula, as for Q.sup.1, Q.sup.2 and Q.sup.3, Q.sup.1 and Q.sup.2, which are the same or different each other, are hydrogen, alkyl groups having 1-4 of carbon atoms, acyl groups having 2-5 of carbon atoms, or protecting groups of the amino group, and Q.sup.3 is a hydrogen or a protecting group of the hydroxyl group; or Q.sup.2 and Q.sup.3 make up an isopropylidene group and Q.sup.1 is a hydrogen or a protecting group of the amino group, Q.sup.4 and Q.sup.5, which are the same or different each other, are hydroxyl groups, acyl groups having 2-5 of carbon atoms, --O--Q.sup.6, or hydrogen; or Q.sup.4 and Q.sup.5 make up a covalent bond, Q.sup.6 is a protecting group of the hydroxyl group, X.sup.1 is --COOH, --CONH.sub.2, --CO--Q.sup.7, --CH.sub.2 OH, or --CH.sub.2 O--Q.sup.8, Q.sup.7 is a protecting group of the carboxyl group, and Q.sup.8 is a protecting group of the hydroxyl group.