Patent ID: 7258734
Filing Date: 2007-08-21
Classification: A61C,A61K,A61L,A61P,C04B,Y10T

Abstract:
1. A method of forming calcium phosphate cement particles with calcium phosphate crystals on the surface of the particles comprising: forming a mixture by contacting calcium phosphate particles with an acidic wetting agent, wherein the calcium phosphate particles comprise tetracalcium phosphate and dicalcium phosphate anhydrous; subjecting the mixture to one or more controlling treatments, wherein at least one of the controlling treatments substantially removes the wetting solution from the mixture, and wherein the controlling treatment is chosen such that the treatment causes the growth of fine crystals or whiskers on the surface of at least a portion of the calcium phosphate particles; and reducing the size of the calcium phosphate particles such that the calcium phosphate particles have an average diameter ranging from 0.05 microns to 100 microns.