Patent ID: 6589573
Filing Date: 2003-07-08
Classification: A61K

Abstract:
A process for producing a xanthine oxidase inhibitor comprising:(a) extracting plant parts of Lagerstroemia speciosa with at least one member selected from the group consisting of water, hot water, and an organic solvent to obtain an extract; (b) adsorbing the extract onto a resin, selected from the group consisting of a styrene-divinyl benzene synthetic resin and a dextran synthetic resin to obtain resin adsorbed components; (c) partitioning the resin adsorbed components by washing away non-adsorbed components with water and then eluting with ethyl acetate to obtain a fraction of ethyl acetate soluble components; (d) purifying and isolating the fraction of ethyl acetate soluble components by high performance liquid chromatography to obtain high performance liquid chromatography separated components as determined by peaks of separation; and (e) recovering a substance from a second peak obtained from the high performance liquid chromatography as an xanthine oxidase inhibitor.