Patent ID: 6686374
Filing Date: 2004-02-03
Classification: A61P,C07D

Abstract:
A compound according to Formula I and a salt, solvate or hydrate thereof, wherein: R represents a group of Formula II; one of A, B, D or E is a N atom, the remainder being CH groups; R1 is SO2Ar; R2, and R4 are independently selected from the group consisting of H and alkyl; represents a single or double bond, with the proviso that there is only one double bond in the ring at a time;Z is C; Ar is an optionally substituted 5-10 membered mono or bi-cyclic aromatic group which can contain up to 2 heteroatoms, selected from O, N, and S, wherein the optional substituents are independently selected from 1-4 members of the group consisting of halo, hydroxy, alkyl, alkoxy, thioalkyl, trifluoromethyl, and trifluoromethoxy.