Patent ID: 6774114
Filing Date: 2004-08-10
Classification: A61K,A61P,A61Q

Abstract:
A topically applicable cosmetic/dermatological composition suited for augmenting the synthesis of epidermal ceramides, and/or improving the barrier function of the skin, and/or treating atopic or seborrhoeic dermatitis, and/or improving the suppleness and/or surface appearance of the skin and/or combating or preventing intrinsic aging of the skin, and/or moisturizing the skin, comprising ascorbic acid in immixture with at least one monosaccharide ester of ascorbic acid and/or at least one metal salt of phosphorylated ascorbic acid, wherein the amount of ascorbic acid is from 0.0001% to 0.01% by weight of said composition; wherein the amount of said at least one monosaccharide ester of ascorbic acid is from 0.001% to 0.1% by weight of said composition and/or the amount of said at least one metal salt of phosphorylated ascorbic acid is from 0.001% to 0.1% by weight of said composition; and wherein said ascorbic acid and monosaccharide ester and/or metal salt are present in a combined, synergistically effective epidermal ceramide synthesis augmenting amount; formulated into a topically applicable, physiologically acceptable vehicle, diluent or carrier therefor.