Patent ID: 8372594
Filing Date: 2013-02-12
Classification: C12Q,G01N

Abstract:
1. A method of determining prognosis, presence of, risk for, progression or abatement of osteoarthritis in a subject, the method comprising: providing a biological sample from a subject; evaluating expression or activity of a first isoform of secretory phospholipase A2 (sPLA2) in the biological sample from the subject, wherein the first isoform is sPLA2 Group IIA (sPLA2-IIA); evaluating expression or activity of at least one other isoform of sPLA2 in the biological sample, and correlating expression or activity of sPLA2-IIA and the at least one other isoform of sPLA2 with a presence, risk, prognosis, progression, or abatement of arthritis.