Patent ID: 6719869
Filing Date: 2004-04-13
Classification: A61F,B01J,B05D,B32B,D06N,D21H

Abstract:
A method of immobilizing particles of an active ingredient and a binder between a backing sheet and a covering sheet, comprising the steps of:applying a mixture comprising of particles of at least one active ingredient, stabilizing particles, and binder particles to the backing sheet to form a layer of the mixture on the backing sheet, wherein the stabilizing particles are larger than the binder particles and greater than about 100 microns in size; placing upon the mixture, the covering sheet; heating the mixture to at least a softening temperature of the binder particles and the stabilizing particles, but below a melting temperature of the backing sheet and the particles of at least one active ingredient, so as to cause the binder particles and the stabilizing particles to soften; and thereafter applying pressure to the backing sheet, the mixture, and the covering sheet wherein the particles of at least one active ingredient are coalesced by the binder particles, and wherein each of the stabilizing particles forms a bond with both the backing sheet and the covering sheet.