Patent ID: 7041461
Filing Date: 2006-05-09
Classification: A01K,A61P,C07K

Abstract:
1. A process for preparing a composition which comprises: (a) determining whether a compound is a mammalian NPFF receptor agonist by a method which comprises contacting cells transfected with and expressing DNA encoding a mammalian NPFF receptor with the compound under conditions permitting the activation of the mammalian NPFF receptor, and detecting an increase in mammalian NPFF receptor activation, so as to thereby determine whether the compound is a mammalian NPFF receptor agonist; (b) recovering the compound free of any mammalian NPFF receptor; and (c) admixing a carrier, thereby preparing the composition; wherein the mammalian NPFF receptor comprises an amino acid sequence which is the same as the sequence of the human NPFF2 receptor encoded by plasmid pCDNA3.1-hNPFF2b (ATCC Accession No. 203255); or the sequence of SEQ ID NO: 6.