Patent ID: 8554488
Filing Date: 2013-10-08
Classification: C12Q,G16B,G16H

Abstract:
1. A method for determining whether a patient is autistic, comprising: (a) obtaining a segmented genomic profile of DNA extracted from a cell of the patient, the segmented genomic profile comprising information about the copy number of a plurality of discrete segments within one or more genomic regions, the one or more genomic regions having been determined by: (b) determining, by computer analysis, a genomic perturbation index value from the segmented genomic profile, wherein said perturbation index value incorporates: (c) comparing the perturbation index value of the patient to a perturbation index value determined from a segmented genomic profile of an individual known to have autism, the segmented genomic profile of the individual known to have autism comprising information about the copy number of a plurality of discrete segments within the same one or more genomic regions identified by the process in step (a); and (d) classifying the patient as autistic or non-autistic based on the comparison of step (c).