Patent ID: 7560239
Filing Date: 2009-07-14
Classification: G01N

Abstract:
1. A method for detecting the presence of one or more non-serologically cross-reactive analyte types in a sample using a competitive homogeneous assay: where the assay detects a plurality of different analyte types that are non-serologically cross-reactive and, where the assay involves analyte and receptor binding pairs such that the presence of one or more different analyte types is determined by enzyme activity reflecting the concentration of analyte when present in excess of a predetermined concentration of the cutoff said method comprising the steps of: (I) combining in an aqueous medium: (II) detecting increased G6PDH activity in the aqueous medium due to competitive binding of the receptors with the analyte types in the sample where analyte types bind receptors permitting the G6PDH-analyte binding pair member conjugates to exhibit maximal enzyme activity; wherein: