Patent ID: 6093204
Filing Date: 2000-07-25
Classification: A61F,A61L

Abstract:
An article of manufacture comprising a substantially non-immunogenic meniscal heterograft for implantation into a human, produced by the process ofa. removing at least a portion of a medial or lateral meniscus from a knee joint of a non-human animal to provide a heterograft;b. washing the heterograft in water and alcohol;c. subjecting the heterograft to at least one treatment selected from the group consisting of exposure to ultraviolet radiation, immersion in alcohol, ozonation, and freeze/thaw cycling; andd. treating the heterograft with a glycosidase to remove surface carbohydrate moieties, whereby the heterograft has substantially the same mechanical properties as a corresponding portion of a native medial or lateral meniscus.