Patent ID: 9133097
Filing Date: 2015-09-15
Classification: A61K,A61P,C07C,Y02A

Abstract:
1. A method of treating a cancer in a mammal, wherein the method comprises administering to the mammal a therapeutically effective amount of a compound selected from the group consisting of: as an isolated stereoisomer or mixture thereof, or a pharmaceutically acceptable salt thereof, wherein at least one of: a) the cancer is associated with activation of AKT, b) the cancer is associated with activation of PI3 kinase, c) the cancer is associated with a deficiency of PTEN activity, d) the cancer is associated with activation of the Wnt signaling pathway, e) the cancer comprises a gastrointestinal cancer, f) the cancer is colon cancer, g) the cancer is breast cancer, h) the cancer is neuroblastoma, i) the cancer is leukemia, or j) the cancer comprises a brain tumor.