Patent ID: 8343483
Filing Date: 2013-01-01
Classification: A01N,A23C,A23G,A23L,A23V,A23Y,A61K,A61P,A61Q,C12N,C12R,Y10S

Abstract:
1. A method of inhibiting growth of dental caries bacteria comprising orally administering to mammals a product comprising cells of a biologically pure culture of at least one strain of Lactobacillus reuteri selected by a method comprising the steps of: a) selecting and growing a strain of Lactobacillus reuteri ; b) evaluating the inhibitory activity against Streptococcus mutans of said Lactobacillus reuteri strains or metabolites or components obtained from a culture of said strain; c) evaluating the adhesion capabilities to oral mucins of said Lactobacillus reuteri strains or metabolites or components obtained from the culture of said strain; and d) selecting the strain of Lactobacillus reuteri exhibiting a good inhibitory activity against Streptococcus mutans in combination with good binding to oral mucins.