Patent ID: 6117663
Filing Date: 2000-09-12
Classification: C07K

Abstract:
A crystal of a Ras-Son of sevenless (Ras-Sos) complex that effectively diffracts X-rays for the determination of the atomic coordinates of the complex to a resolution of better than 5.0 Angstroms; wherein the Ras-Sos complex consists of a fragment of Ras consisting of amino acids 1 to 166 of SEQ ID NO:1 and a fragment of Sos consisting of amino acids 564 to 1049 of SEQ ID NO:2; wherein said crystal has a space group selected from the group consisting of 1422 with unit cell dimensions of a=142.7, b=142.7 and c=207.9, and I4 with unit cell dimensions of a=124.6.ANG., b=124.6.ANG. and c=314.9 .ANG..