Patent ID: 7179647
Filing Date: 2007-02-20
Classification: A61P,C12N,C12P

Abstract:
1. An isolated nucleic acid encoding a polypeptide that elongates C 16 - or C 18 -fatty acids with at least two double bonds in the fatty acid by at least two carbon atoms, wherein C 18:3 Δ5t,9,12 , C 20:3 Δ8,11,14 , C 20:4 Δ5,8,11,14 and C 20:5 Δ5,8,11,14,17 are not elongated and wherein said nucleotide sequence is selected from the group consisting of: a) the sequence of SEQ ID NO:1; b) a nucleic acid sequence which, in accordance with degeneracy of the genetic code, is derived from the amino acid sequence of SEQ ID:2; and c) derivatives of the sequence of SEQ ID NO:1 which encode polypeptides with at least 95% homology with the amino acid sequence of SEQ ID NO:2, wherein the sequence acts as a C