Patent ID: 6635238
Filing Date: 2003-10-21
Classification: A61K,A61Q,C12N

Abstract:
A method for the prophylactic and therapeutic treatment of bacterial dental caries and bacterial periodontal diseases, wherein the method comprises delivering to a mouth, gums and teeth at least one composition comprising:(i) an effective amount of at least one lytic enzyme genetically coded for by a specific bacteriophage specific for a specific bacteria causing said bacterial dental caries or bacterial periodontal disease, wherein said at least one said lytic enzyme is specific for and has the ability to digest a cell wall of one of said specific bacteria and is coded for by the same said bacteriophage capbale of infecting said bacteria being digested; and (ii) a carrier for delivering said at least one said lytic enzyme to the mouth, the gums, and the teeth, said carrier selected from the group consisting of a mouth wash, mouth rinse, topical gel, topical ointment, toothpaste, tooth powder, slow release implant, slow release coating or chewing gum.