Patent ID: 6406711
Filing Date: 2002-06-18
Classification: A61F,A61L

Abstract:
A method of regenerating bone or expediting formation of new bone which comprises applying to bone a bone-generating composition having a bone generating component and a biocompatible substrate, wherein the bone generating component is a polyphosphoric acid or a corresponding polyphosphate, and the polyphosphoric acid is a member selected from the group consisting of a) a linear condensed polyphosphoric acid which is a dehydrocondensate of an orthophosphoric acid, b) a side-chain polyphosphoric acid wherein the side chain comprises an organic group, c) a cyclic polyphosphoric acid, and d) a polyphosphoric acid which is a compound of the formula:(PnO3n+1)(n+2)H wherein n is an integer of at least 2, and having a structure wherein two or more PO4 tetrahedrons are linearly bound with a top oxygen atom.