Patent ID: 9017693
Filing Date: 2015-04-28
Classification: A61K,A61P,C07K

Abstract:
1. Apoptotically active substance comprising a peptide having one of the amino acid sequences selected from the group consisting of M-V-V-Y-F-R (SEQ ID NO: 12), R-A-Y-V-V-A (SEQ ID NO: 13), R-L-Y-V-V-M (SEQ ID NO: 14), R-P-Y-V-V-M (SEQ ID NO: 15), R-S-Y-V-V-M (SEQ ID NO: 16), R-C-Y-V-V-M (SEQ ID NO: 17), m-v-v-y-f-r (D-amino acids) (SEQ ID NO: 18) and m-v-v-y-a-r (D-amino acids) (SEQ ID NO: 19), wherein the peptide induces apoptosis wherein the apoptotically active peptide has less than 15 amino acids.