Patent ID: 7769423
Filing Date: 2010-08-03
Classification: A61B,A61K,G01R

Abstract:
1. A method of predicting efficacy of a treatment in a subject, the method comprising: administering to a subject a liposome composition comprising: (i) a contrast agent; (ii) a compound of interest; and (iii) a liposome encapsulating the contrast agent and the compound of interest; monitoring accumulation of the compound of interest at a desired site in vivo by magnetic resonance imaging, wherein the monitoring comprises monitoring release of the contents of the liposome at the desired site by monitoring an increase in the presence of the contrast agent released from the liposome at the desired site as the contents of the liposome are being released at the desired site; and predicting efficacy of treatment based on accumulation of the compound of interest at the desired site.