Patent ID: 8877829
Filing Date: 2014-11-04
Classification: C07F,C08G

Abstract:
1. A biomedical device obtained from a polymerization product of a monomer mixture comprising a water extractable biomedical device forming cationic non-hydroxyl-containing organosilicon-containing monomer, wherein the water extractable medical device forming cationic non-hydroxyl-containing organosilicon-containing monomer is obtained by the method comprising (a) dissolving a hydride containing siloxane compound in a solvent or combination of solvents; (b) treating the dissolved hydride containing siloxane compound with an allylic halide and a hydrosilation catalyst to form a first reaction mixture; (c) heating the first reaction mixture under a nitrogen atmosphere for a sufficient time to result in the quantitative loss of reactants as determined by appropriate analytical technique thus providing a monomer mixture; (d) cooling the monomer mixture; (e) concentrating the cooled mixture; (f) dissolving the cooled mixture in a solvent appropriate for nucleophilic substitution; (g) treating the cooled mixture containing the solvent appropriate for nucleophilic substitution with a tertiary amino-vinyl compound to form a second reaction mixture; (h) heating the second reaction mixture at a temperature sufficient to promote reaction without causing gelation; (i) removing any remaining solvent to provide a product containing material; and, (j) purifying the product containing material to yield the water extractable medical device forming cationic non-hydroxyl-containing organosilicon-containing monomer.