Patent ID: 6475727
Filing Date: 2002-11-05
Classification: C12Q

Abstract:
A primer which specifically hybridizes to a nucleic acid molecule complementary to a messenger RNA transcribed from a gene encoding a MAGE tumor-specific antigen or a fragment thereof or to a complementary strand thereof, said primer being selected from primers having at least 15 contiguous 3â€²-end nucleotides as set forth in the sequences provided in one of the following groups of primers:(a)5â€²-gtagagttcggccgaaggaac-3â€²(SEQ ID NO: 1) 5â€²-caggagctgggcaatgaagac-3â€²(SEQ ID NO: 2) 5â€²-cattgaaggagaagatctgcct-3â€²(SEQ ID NO: 3) 5â€²-gagtagaagaggaagaagcggt-3â€²(SEQ ID NO: 4) 5â€²-gaagccggcccaggctcg-3â€²(SEQ ID NO: 5) 5â€²-gatgactctggtcagggcaa-3â€²(SEQ ID NO: 6) 5â€²-caccaaggagaagatctgcct-3â€²(SEQ ID NO: 7) 5â€²-tcctcagtagtaggagcctgt-3â€²(SEQ ID NO: 8) 5â€²-tccgtgaggaggcaaggttc-3â€²(SEQ ID NO: 9) 5â€²-atcggattgactccagagagta-3â€²(SEQ ID NO: 10); or (b)5â€²-tagagttcggccgaaggaac-3â€²(SEQ ID NO: 11) 5â€²-ctgggcaatgaagacccaca-3â€²(SEQ ID NO: 12) 5â€²-cattgaaggagaagatctgcct-3â€²(SEQ ID NO: 13) 5â€²-caggcttgcagtgctgactc-3â€²(SEQ ID NO: 14) 5â€²-ggctcggtgaggaggcaag-3â€²(SEQ ID NO: 15) 5â€²-gatgactctggtcagggcaa-3â€²(SEQ ID NO: 16) 5â€²-caccaaggagaagatctgcct-3â€²(SEQ ID NO: 17) 5â€²-caggcttgcagtgctgactct-3â€²(SEQ ID NO: 18) 5â€²-tccgtgaggaggcaaggttc-3â€²(SEQ ID NO: 19) 5â€²-gagcctgcgcacccaccaa-3â€²(SEQ ID NO: 20).