Patent ID: 8821940
Filing Date: 2014-09-02
Classification: A61B,A61K,A61N,A61P,A61Q,B82Y

Abstract:
1. A method of localizing thermal damage to a targeted portion of a skin tissue, comprising: applying a composition to a skin surface of a skin tissue, wherein the skin tissue comprises a targeted portion of the skin tissue and a non-targeted portion of the skin tissue, wherein said composition comprises a plurality of unassembled plasmonic nanoparticles, wherein the unassembled plasmonic nanoparticles comprise a conductive metal portion, wherein the conductive metal portion comprises at least one of gold or silver, wherein the unassembled plasmonic nanoparticles have a size in a range of 10 nm to 300 nm, wherein the unassembled plasmonic nanoparticles comprise a coating that coats the conductive metal portion, wherein said coating facilitates selective removal from the non-targeted portion of the skin tissue; wherein the coating comprises at least one of silica or polyethylene glycol (PEG), wherein the unassembled plasmonic nanoparticles have a concentration of 10 distributing the composition from the skin surface to the targeted portion of the skin tissue comprising an epidermis and a dermis; selectively removing the composition from the non-targeted portion of the skin tissue, while leaving the composition localized at the targeted portion of the skin tissue; and irradiating the composition with an infrared light source thereby inducing a plurality of surface plasmons in said unassembled plasmonic nanoparticles, thereby localizing thermal damage to said targeted portion of the skin tissue.