Patent ID: 8258266
Filing Date: 2012-09-04
Classification: A61K,A61P,C07K

Abstract:
1. An isolated monoclonal antibody, or antigen binding portion thereof, comprising: (a) a heavy chain variable region CDR1 comprising SEQ ID NO: 5; (b) a heavy chain variable region CDR2 comprising SEQ ID NO: 17; (c) a heavy chain variable region CDR3 comprising SEQ ID NO: 28; (d) a light chain variable region CDR1 comprising SEQ ID NO: 55; (e) a light chain variable region CDR2 comprising SEQ ID NO: 66; and (f) a light chain variable region CDR3 comprising SEQ ID NO: 77, wherein the antibody specifically binds IP-10 (SEQ ID NO: 121).