Patent ID: 8158626
Filing Date: 2012-04-17
Classification: A61P,C07D

Abstract:
1. A method of therapeutically treating cancer in a mammal comprised of administering to said mammal a therapeutically effective amount of a compound selected from Formula Ia and Formula Ib: and stereoisomers, geometric isomers, tautomers, or pharmaceutically acceptable salts thereof, wherein: R R R R or R where said alkyl, alkenyl, alkynyl, carbocyclyl, heterocyclyl, aryl, and heteroaryl, are optionally substituted with one or more groups independently selected from F, Cl, Br, I, CN, CF Y is O, S, or NR m is 0, 1, 2, 3, 4, 5 or 6; and n is 1, 2, 3, 4, 5 or 6; with the proviso that, when R wherein the cancer is selected from breast and prostate cancer.