Patent ID: 6573273
Filing Date: 2003-06-03
Classification: A61K,A61P,C07D,Y02A

Abstract:
A compound of the formula (I): whereinbonds represented by dashed lines are present or absent; R1 is â€”C2-6 alkyl-NR3â€”CYâ€”NR5â€”R4 wherein Y is &boxH;O or &boxH;S; R4 is hydrogen, alkyl, aryl, or substituted aryl; R2 is selected from the group consisting of: -hydrogen; -alkyl; -alkenyl; -aryl; -substituted aryl; -heteroaryl; -substituted heteroaryl; -alkyl-O-aryl; -alkyl-O-alkyl; -alkyl-O-alkenyl; and -alkyl or alkenyl substituted by one of more substituents selected from the group consisting of: â€”OH; -halogen; â€”N(R3)2; â€”COâ€”N(R3)2; â€”COâ€”C1-10 alkyl; â€”COâ€”Oâ€”C1-10 alkyl; â€”N3; -aryl; -substituted aryl; -heterocyclyl; -substituted heterocyclyl; â€”CO-aryl; â€”CO-(substituted aryl); â€”CO-heteroaryl; and â€”CO-(substituted heteroaryl); each R3 is independently selected from the group consisting of hydrogen and C1-10 alkyl; R5 is selected from the group consisting of hydrogen and C1-10 alkyl, or R4 and R5 can combine to form a 3 to 7 membered heterocyclic or substituted heterocyclic ring; n is 0 to 4 and each R present is independently selected from the group consisting of C1-10 alkyl, C1-10 alkoxy, halogen and triflutoromethyl, or a pharmaceutically acceptable salt thereof.