Patent ID: 6410515
Filing Date: 2002-06-25
Classification: A61K,C07K

Abstract:
A method of immunosuppressing the immune system in an animal comprising administering an effective amount of a peptide of a formula I:X-A-D-Trp-Yâ€ƒâ€ƒ(I) wherein X is selected from the group comprising hydrogen, glycine, alanine, leucine, isoleucine, valine, N-valine, proline, tyrosine, phenylalanine, tryptophan, D-alanine, D-leucine, D-isoleucine, D-valine, D-N-valine, D-proline, D-tyrosine, D-phenylalanine, D-tryptophan, &ggr;-aminobutyric acid, and &zgr;-aminocaproic acid; A is selected from the group comprising D-glutamic acid and D-iso-glutamic acid; and Y is selected from the group comprising glycine, alanine, leucine, isoleucine, valine, N-valine, proline, tyrosine, phenylalanine, tryptophan, D-alanine, D-leucine, D-isoleucine, D-valine, D-N-valine, D-proline, D-tyrosine, D-phenylalanine, D-tryptophan, &ggr;-aminobutyric acid, &zgr;-aminocaproic acid, hydroxyl and an amide group, to an animal in need thereof.