Patent ID: 7888487
Filing Date: 2011-02-15
Classification: A61K,A61P,C07D,C07H,Y10S

Abstract:
1. A method for preparing a compound represented by the general formula (I) wherein R one of Q and T represents a group selected from  and the other represents a group represented by the formula: —(CH R represents a C [substituent group (A)]: a halogen atom, a nitro group, a cyano group, an oxo group, -G [substituent group (B)]: a halogen atom, a nitro group, a cyano group, -G in the above substituent group (A) and/or (B), G G G G [substituent group (C)]: a halogen atom, a nitro group, a cyano group, an oxo group, -G [substituent group (D)]: a halogen atom, a nitro group, a cyano group, -G in the substituent group (C) and/or (D), G G characterized by subjecting a pyrazole compound represented by the general formula (III) wherein R one of Q R [substituent group (A1)]: a halogen atom, a nitro group, a cyano group, an oxo group, -G [substituent group (B1)]: a halogen atom, a nitro group, a cyano group, -G in the above substituent group (A1) and/or (B1), G G G G G [substituent group (C1)]: a halogen atom, a nitro group, a cyano group, an oxo group, -G [substituent group (D1)]: a halogen atom, a nitro group, a cyano group, -G in the substituent group (C1) and/or (D1), G G G to glycosidation using a sugar donor represented by the general formula (IV) wherein G represents a group selected from a β-D-glucopyranosyl group, a β-D-mannopyranosyl group, an α-D-glucopyranosyl, an α-D-mannopyranosyl group, β-D-2-deoxyglucopyranosyl group or an α-D-2-deoxyglucopyranosyl group, which has one to four hydroxy-protective groups at the hydroxy groups; and X represents a leaving group, and removing the protective groups.