Patent ID: 6906050
Filing Date: 2005-06-14
Classification: A61K,A61P,C07D

Abstract:
1. A compound of formula II: wherein R (CH C(X) CO (CH (CH CONH(R S(R (CH (CH SO Aryl or substituted aryl, which may bear one or more substituents with a molecular weight of less than or equal to about 100,000 daltons; R with the proviso that at least one of the R wherein R 24 is selected from a hydrogen, a straight or branched chain C 1 -C 7 alkyl group, a phenyl or benzyl group; L 1 , L 2 , L 3 , L 4 , independently of one another, are selected from a hydrogen atom or a metal ion equivalent of an element of the atomic numbers 20-32, 37-39, 42-51, or 57-83, which may be radioactive, provided that at least two of L 1 , L 2 , L 3 and L 4 are metal ion equivalents, that other anions are present to compensate for optionally present charges on the porphyrin, and free carboxyhic acid groups that are not required for complexing are optionally present as salts with physiologically compatible inorganic cations, or organic cations, or as esters or amides; and wherein M is 2H or a diamagnetic or paramagnetic photoactive metal ion selected from Ga