Patent ID: 6284736
Filing Date: 2001-09-04
Classification: A61P,C07H

Abstract:
A compound of formula (I), or a pharmaceutically acceptable salt thereof: ##STR36##wherein R.sub.1 is a carboxylic acid group, an ester thereof selected from the group consisting of alkoxycarbonyl, alkenyloxycarbonyl, aryloxycarbonyl, heteroaryloxycarbonyl, aralkyloxycarbonyl, and heteroaralkyloxycarbonyl, or a primary amide thereof, or --CHO, wherein any alkyl, alkenyl, or alkoxy group independently contains from one to six carbon atoms, wherein any aryl group is selected from the group consisting of phenyl and naphthyl either being unsubstituted or mono-, di-, or tri-substituted by a substituent selected from the group consisting of carboxy, C.sub.1-6 alkoxycarbonyl, hydroxy-C.sub.1-6 alkyl, C.sub.1-6 alkoxy, halogen, and an amino optionally substituted by C.sub.1-6 alkyl, and wherein any heteroaryl group is a 5- or 6-membered monocyclic or a 9- or 10-membered bicyclic group containing one or two heteroatoms independently selected from the group consisting of nitrogen, oxygen, and sulfur; R.sub.2 is hydroxy, C.sub.1-8 alkoxy or a fluorine atom; and R.sub.3 is an amino group.