Patent ID: 7807833
Filing Date: 2010-10-05
Classification: C07C,C07D,Y02P

Abstract:
1. An intermediate compound represented by formula 3, wherein the carbon at a 10 th site at a backbone of a 5 membered ring structure of ecteinascidins is bonded with H, wherein, Y is oxygen or NH, R 1 and R 4 are H or an alkyl group of carbon number 4 or less, R 2 is an alkoxycarbonyl group which can be substituted by halogen, a lower alkyl sulfonyl or an aryl sulfonyl group, X 1 is a hydrogen, a protecting group of an amino group or silyl groups consisting of an acyl group of carbon number 4 or less, t-butyldiphenylsilyl (TBDPS), triisopropylsilyl (TIPS), t-butyldimethylsilyl (TBS), triethylsilyl (TES), and trimethylsilyl (TMS), X 2 , X 3 and X 4 are independently selected from the group consisting of H or an alkyl group of carbon number 4 or less, an alkoxyalkyl group, an allyl group, or an alkyl or arylsulfonyl group.