Patent ID: 8101211
Filing Date: 2012-01-24
Classification: A61K,A61P,A61Q

Abstract:
1. A method for retarding skin aging comprising applying to the skin of a human a pharmaceutically effective amount of a composition which comprises a base and/or one or more additives medicinally acceptable for external dermal application and a pharmaceutically effective amount of one or more plant extracts having an active oxygen eliminating or scavenging activity which provides an age-retardin effect, said active oxygen eliminating or scavenging activity evaluated by an O 2− elimination rate of ((A−B)/A)×100 being more than 30%, wherein A denotes the absorbance of a control, B denotes the absorbance with the addition of a sample, wherein the OD at 562 nm is measured after incubating a color reagent solution containing Nitro Blue Tetrazolium and xanthine, xanthine oxidase and the plant extract at a concentration of 0.025% at 37° C. for 30 minutes, the plant extract being selected from the group consisting of extracts of Suei-Ding Hsiang ( Ludwigia octovalvis ), Yui-Jen-Sau ( Anisomeles indica ), Ban-Ji-Lien ( Scutellaria rivularis ), Ma-Bien-Sau ( Verbana officinalis ), Ku-Chi ( Physalis angulata ), Bai-Hua-Tsai ( Cleome gynandra ), Sarng-Han-Sau ( Vernonia cinerae ), Ma-An-Tung ( Ipomoea pes - caprae ), Hua-Shi-Su ( Clerodendrum calamitosum ), Gin-Di-Lo ( Drosera burmanni ), Bai-Yeh-Chi-Ken ( Elaeagnus oldhamii ), Yui-Yeh-Gin-Hua ( Mussaenda parviflora ), Chou-Mor-Li ( Clerodendrum philippinum ), Da-Ching ( Clerodendrum crytophyllum ), Bai-Lorng-Chun-Hua ( Clerodendrum paniculataum var. albifloraum ), Mu-Chu-Ma ( Boehmeria densiflora ), Ya-Jou ( Sapium sebiferum ), San-Yeh-Pu-Tao ( Tetrastigma dentatum ), Gin-Shi-Liu ( Bredia oldhami ), Ha-Sai-Hua ( Staurogyne concinnula ), Ci-Yen-Suei-Ding-Hsiang ( Ludwigia hyssopifolia ), Tie-Hsien-Jei ( Adiantum flabellulatum ), Huang-Ging ( Vitix negundo ), Su-Chi-Sau ( Gnaphalium affine ), Zu-Chi-Sau ( Euphorbia hirta ), Ding-Di-Wu-Gong ( Torenia concolor var. formosana ), Da-Gia-Sau ( Euphorbia formosana ), Taiwan Kou-Tung ( Uncaria hirsuta ), Cher-Chien-Sau ( Plantago formosana ), Gin-Gien-Sau ( Rubia lanceolata ), Tu-Chi-Tsai ( Ixeris chinensis ), Dau-Sharng-Sau ( Ixeris laevigata var. oldhami ), Ku-Lam-Parn ( Clerodendrum inerme ), Du-Horng-Hua ( Callicarpa formosana ), Torng-Chuei-Yui-Di-Sau ( Pratia nummularia ) and San-Yeh-Wu-Gia ( Acanthopanax trifoliatus ).