Patent ID: 6623972
Filing Date: 2003-09-23
Classification: G01N

Abstract:
A method for the determination, quantification and monitoring of extracellular hemoglobin in a whole blood, plasma or serum sample performed on an automated hematology analyzer having at least two analytic channels for hemoglobin measurement, comprising:(a) determining total hemoglobin concentration in an aliquot of the sample in a hemoglobin analytic channel of the analyzer; (b) determining cellular hemoglobin concentration in the sample aliquot in a red blood cell analytic channel of the analyzer; and (c) calculating the difference between the total hemoglobin concentration determined from the hemoglobin analytic channel and the cellular hemoglobin concentration determined from the red blood cell analytic channel of the analyzer to yield the extracellular hemoglobin concentration in the whole blood, plasma, or serum sample.