Patent ID: 6210921
Filing Date: 2001-04-03
Classification: A01K,A61K,C07K

Abstract:
An isolated nucleic acid molecule which hybridizes under stringent conditions to a second nucleic acid molecule, said second nucleic acid molecule comprising SEQ ID No:1 or the complement thereto, said stringent conditions comprising hybridization in 6.times.sodium chloride/sodium citrate (SSC) at about 45.degree. C., followed by one or more washes in 0.2.times.SSC, 0.1% SDS at 50-65.degree. C., wherein the isolated nucleic acid molecule encodes a protein having one or more of the following functions: (1) it can serve as a receptor for coxsackievirus or adenovirus; (2) it can modulate the activity of coxsackievirus or adenovirus; and (3) it can modulate the attachment process of coxsackievirus or adenovirus in a cell that is responsive to such pathogens.