Patent ID: 8865742
Filing Date: 2014-10-21
Classification: A61P,C07C,C07D

Abstract:
1. A process for the preparation of a compound formula (I), or a salt thereof, wherein R R R R the process comprising the steps of: a) reacting an anthranilate derivative of formula (7A) wherein R is an alkyl, aryl or alkylaryl, with a 3-oxopropanoic acid derivative of formula (8A) wherein X is OH or a leaving group, so as to obtain a compound of formula (9A): b) optionally, saponifying the ester group CO wherein Y is a leaving group; and c) converting compound (9A) obtained in step (a), or compound (11A) obtained in step (b) to a compound of formula (I) or a salt thereof in the presence of a base.