Patent ID: 8574629
Filing Date: 2013-11-05
Classification: A61L,A61P

Abstract:
1. An injectable hydrogel that comprises: a hydrogel matrix comprising single phase cross-linked biopolymer(s), and previously cross-linked biopolymer hydrogel particles co-cross-linked with said matrix, wherein the biopolymer(s) is (are) selected from the group consisting of sodium hyaluronate, chondroitin sulfate, keratan, keratan sulfate, heparin, heparan sulfate, cellulose and its derivatives, alginates, xanthan, carrageenan, proteins, nucleic acids and mixtures thereof, the total biopolymer concentration is between 0.01 and 100 mg/ml, the mass percent of particles in the single-phase matrix is between 1 and 99%, and the particles have an inside diameter of between 50 and 1000 micrometers.