Patent ID: 7923462
Filing Date: 2011-04-12
Classification: A61P,C07D

Abstract:
1. A compound represented by general formula (I): or a pharmaceutically acceptable salt thereof, wherein a) a halo-lower alkyl group, b) a lower acyl group, c) a halo-lower alkylcarbonyl group, d) a cycloalkylcarbonyl group, e) an arylcarbonyl group, wherein the ring of the arylcarbonyl group is unsubstituted or substituted with 1 to 5 substituents selected from the group consisting of a halogen atom, a lower alkyl group, a halo-lower alkyl group, a lower alkoxy group, a cycloalkyl-lower alkoxy group, a hydroxy group, a lower alkoxycarbonyl group, —C(O)NR f) a heteroarylcarbonyl group, wherein the ring of the heteroarylcarbonyl group is unsubstituted or substituted with 1 to 3 substituents selected from the group consisting of a halogen atom, a lower alkyl group, a halo-lower alkyl group and a lower alkoxy group, g) an aralkylcarbonyl group, wherein the ring of the aralkylcarbonyl group is unsubstituted or substituted with 1 to 5 substituents selected from the group consisting of a halogen atom, a lower alkyl group, a halo-lower alkyl group and a lower alkoxy group, h) an aryloxy-lower alkylcarbonyl group, wherein the ring of the aryloxy-lower alkylcarbonyl group is unsubstituted or substituted with 1 to 5 substituents selected from the group consisting of a halogen atom, a lower alkyl group, a halo-lower alkyl group and a lower alkoxy group, i) a lower alkoxycarbonyl group, j) a cycloalkyloxycarbonyl group, k) a lower alkoxy-lower alkoxycarbonyl group, l) a carboxy group, m) a cyano group, n) —C(O)NR o) —C(O)C(O)NR p) a lower alkylsulfonyl group, q) —SO r) a heteroaryl group, wherein the ring of the heteroaryl group is unsubstituted or substituted with 1 to 3 substituents selected from the group consisting of a halogen atom, a lower alkyl group, a halo-lower alkyl group and a lower alkoxy group; a) a lower alkyl group, b) a halo-lower alkyl group, c) a cycloalkyl group, d) a heterocycloalkyl group, e) a lower alkoxy-lower alkyl group, f) an aryloxy-lower alkyl group, g) a lower alkoxycarbonyl-lower alkyl group or h) a hydroxy-lower alkyl group; and R