Patent ID: 6022958
Filing Date: 2000-02-08
Classification: A61K,C07K,C12Q

Abstract:
An isolated DNA sequence encoding a carcinoembryonic antigen (CEA) family member polypeptide, said isolated DNA sequence hybridizing to a nucleic acid sequence selected from the group consisting of TM-2 (SEQ ID NO.: 1), TM-3 (SEQ ID NO.: 2), KGCEA-1 (SEQ ID NO.: 8) and KGCEA-2 (SEQ ID NO.: 9) under the following conditions:(a) hybridization in 2.times. SSSPE, 5.times. Denhardt's solution and 100 .mu.g of denatured salmon sperm DNA per ml at 68.degree. C., followed by(b) washing in 0.2.times. SSC, 0.25% SDS at 68.degree. C.;and said CEA family member polypeptide binding an antibody generated by immunizing an animal with intact CEA;wherein the isolated DNA sequence is not cLV7.