Patent ID: 7033761
Filing Date: 2006-04-25
Classification: B01J,B01L,B82Y,C40B,G01N

Abstract:
1. A method for forming a miniarray on a miniarray substrate, said miniarray comprising locations or spots that contain an analyte specific reagent for detecting an analyte in a sample, said method comprises the steps of: (a) aspirating a solution of each analyte specific reagent into dispensers comprising pipette tips spaced 9 mm or 4.5 mm center to center to load multiple reagent samples and said dispensers connected to a syringe pump; (b) pressuring nanoliter quantities of defined droplets of said analyte specific reagent from the pipette tips of said dispensers that has been loaded with microliter quantities of said analyte specific reagent; (c) touching said droplets to said miniarray substrate and causing said droplets to release through gravity which is perfomed by applying an electromechanical force to the tips of said dispensers, thereby spotting specific locations or spots on said substrate with a specific volume of said analyte specific reagent, wherein said locations or spots have a center-to-center spacing of in the range of 1 mm to 3 mm; and (d) repeating steps (a) to (c) until said miniarray is fabricated.