Patent ID: 6436947
Filing Date: 2002-08-20
Classification: A61P,C07D

Abstract:
A method of suppressing adaptive immunity in a patient in need of treatment for allograft rejection comprising administering to said patient an effective immunosuppressive amount of a compound selected from the group consisting of(1R,3R)-trans-1-(9-adenyl)-3-hydroxycyclopentane; (1S,3S)-trans-1-(9-adenyl)-3-hydroxycyclopentane; (1R,3R)-trans-1- [9-(6-amino-2-chloropurinyl)]-cyclopentan-3-ol; and (1R,3R)-trans-1-[9-(2,6-diamino)purine]-cyclopentan-3-ol, or a pharmaceutically acceptable salt thereof.