Patent ID: 6156873
Filing Date: 2000-12-05
Classification: A61K,C07F

Abstract:
Dendrimeric compounds of general formula IX--[L--(BiR.sup.1 R.sup.2).sub.n ].sub.b (I)wherebyX stands as a central unit for O, S, N, P, C, Si, Sn, Ge, Bi, or for an aryl, heteroaryl, alkyl or cycloalkyl group, which can contain heteroatoms and/or alkyl, hydroxy, polyhydroxyalkyl substituents and/or ester, amide, thioester, thioamide, acetal, ketal, thioacetal, thioketal, disulfide, anhydride and/or urea groups, whereby X has base multiplicity b,L independently of one another, stand for a C.sub.1 -C.sub.10 alkylene group, which can be hydroxy-substituted in zero to ten places, and can contain zero to ten aryl or heteroaryl, disulfide, anhydride, thioketal, thioacetal, ketal, ether, ester, thioether, thioester, amide, thioamide, urea, sulfonate, sulfonamide, phosphonate or phosphoric acid amid groups,n is 1 to 10,b is the base multiplicity of the central unit,R.sup.1, R.sup.2, independently of one another, stand for another unit of formula IaL--BiR.sup.1 R.sup.2 (Ia)orR.sup.1, R.sup.2, independently of one another, stand for a branched or unbranched C.sub.6 -C.sub.10 aryl or benzyl group that is hydroxy-substituted in zero to six places, an ether group --OR.sup.3, ester group --COOR.sup.3, thioether group --SR.sup.3, thioester group --COSR.sup.3, amide group --CONR.sup.3 R.sup.4 or thioamide group --CSNR.sup.3 R.sup.4, in whichR.sup.3, independently of one another, stand for a branched or unbranched C.sub.1 -C.sub.6 alkyl group that is hydroxy-substituted in zero to six places, a C.sub.6 -C.sub.10 aryl or benzyl group that is hydroxy-substituted in zero to six places,R.sup.4, independently of one another, stand for a hydrogen atom or a branched or unbranched C.sub.6 -C.sub.10 aryl or benzyl group that is hydroxy-substituted in zero to six places.