Patent ID: 8734890
Filing Date: 2014-05-27
Classification: B82Y,G01N,G03F,Y10T

Abstract:
1. A method for forming a molecularly imprinted polymer biosensor, comprising: (a) preparing a reaction solution including an imprinting molecule, a functional monomer, an initiator, and a crosslinking agent, wherein a molar ratio of the imprinting molecule, the functional monomer, the initiator and the crosslinking agent with respect to each other in the reaction solution ranges from about 1:4:30:0.17 to 1:4:30:0.85; (b) disposing the reaction solution in a space between upper and lower substrates each of which is made of a light-transmissible material; (c) disposing on the upper substrate a photomask having a patterned hole; (d) irradiating the reaction solution through the patterned hole of the photomask and the upper substrate so that the reaction solution undergoes polymerization to form a polymer between the upper and lower substrates, wherein step (d) is conducted with an irradiation energy ranging from 16 J/cm (e) removing the upper substrate after the polymer is formed on the lower substrate; and (f) extracting the imprinting molecule from the polymer so that a patterned molecularly imprinted polymer film is formed on the lower substrate.