Patent ID: 7816359
Filing Date: 2010-10-19
Classification: A61P,C07D

Abstract:
1. A pharmaceutical composition comprising, a) one or more pharmaceutically acceptable excipients, and b) at least one pharmaceutically active compound of formula IV R R R and one of the radicals R wherein R 10 is 4-pyrazinyl, 1-methyl-1H-pyrrolyl, amino- or amino-lower alkyl-substituted phenyl wherein the amino group in each case is free, alkylated or acylated, 1H-indolyl or 1H-imidazolyl bonded at a five-membered ring carbon atom, or unsubstituted or lower alkyl-substituted pyridyl bonded at a ring carbon atom and unsubstituted or substituted at the nitrogen atom by oxygen, and R 11 and R 12 are each independently of the other hydrogen or lower alkyl and the other two radicals are hydrogen, lower alkyl, benzyl or phenyl, or a pharmaceutically acceptable salt or crystal form thereof; and c) between 0.00001% and 5% by weight of at least one compound of formula I wherein R R R or a salt or crystal form thereof.