Patent ID: 8324418
Filing Date: 2012-12-04
Classification: C07F

Abstract:
1. A process for the production of an organic dithiopyrophosphate of formula wherein R comprising the steps of wherein R in an organic solvent with thiophosphoryl chloride in the presence of a base, to obtain a 2-chloro-2-thioxo-1,3,2-dioxaphosphorinane of formula wherein R characterized in that 3-methylpyridine is used both as an organic solvent and as a base in steps (i) and (ii), and wherein steps (i) and (ii) are conducted as a one-pot reaction without isolating the 2-chloro-2-thioxo-1,3,2-dioxaphosphorinane intermediate (III), and wherein in step (i) the thiophosphoryl chloride is added to a solution of the 1,3-diol (II) in 3-methylpyridine and in step (ii) the water is added to the reaction mixture obtained in step (i); and wherein the addition of water is started before the addition of thiophosphoryl chloride is completed.