Patent ID: 9012437
Filing Date: 2015-04-21
Classification: A61K,A61P

Abstract:
1. A method for treating an inflammation-mediated condition of the eye comprising: implanting into the vitreous of the eye a bioerodible implant consisting of dexamethasone and a bioerodible polymer, wherein the implant delivers the dexamethasone to the vitreous in an amount sufficient to reach a concentration equivalent to at least about 0.05 μg/mL dexamethasone within about 48 hours, and maintains a concentration equivalent to at least about 0.03 μg/mL dexamethasone for at least about three weeks, wherein the implant is produced by an extrusion method, wherein the total weight of the implant is about 500-1000 μg, and wherein the inflammation-mediated condition of the eye is selected from the group consisting of macular edema, acute macular degeneration, retinal detachment, or proliferative vitreoretinopathy (PVR).