Patent ID: 7282498
Filing Date: 2007-10-16
Classification: A61P,C07D

Abstract:
1. A compound of the formula: or a pharmaceutically acceptable salt thereof, wherein: R is hydroxy, alkyl or alkoxy, where each alkyl is optionally substituted with oxo, haloalkyl, haloalkoxy, halogen, cyano, hydroxy, alkyl, nitro, azido, alkanoyl, carboxamido, alkoxy, aryloxy, alkylthio, alkylsulfinyl, alkylsulfonyl, amino, mono or dialkylamino, aryl, arylalkyl, arylalkoxy, heteroaryl or heterocycloalkyl; or R is —O-aryl or aryl, each of which is optionally substituted with halogen, cyano, hydroxyl, nitro, azido, alkanoyl, carboxamido, alkyl, alkoxy, aryloxy, haloalkyl, haloalkoxy, alkylthio alkylsulfinyl, alkylsulfonyl, amino, mono or di(alkyl)amino, aryl, arylalkyl, arylalkoxy, heteroaryl or heterocycloalkyl; R Ar is aryl, optionally substituted with 1, 2, or 3 substituents independently selected from the group consisting of oxo, haloalkyl, haloalkoxy, halogen, cyano, hydroxy, nitro, azido, alkanoyl, carboxamido, alkyl substituted with 0-2 R