Patent ID: 8951536
Filing Date: 2015-02-10
Classification: A61K,A61P,C07D

Abstract:
1. A method of inhibiting immunosuppression or treating a cancer selected from melanoma, ovarian cancer, and breast cancer, in a patient comprising administering to said patient an effective amount of a compound of Formula Ia: or a pharmaceutically acceptable salt thereof, wherein: U is N; V is O; W is N, wherein the five-membered ring containing U, V, and W is an aromatic heterocycle; A is aryl, or heteroaryl, each optionally substituted by 1, 2, 3, 4, or 5 substituents independently selected from halo, C R is H; R Q is OR R or R Cy, Cy R R R R R R R R or R R or R R or R R or R R or R R R R p is 1, 2, 3, 4, 5.