Patent ID: 6100248
Filing Date: 2000-08-08
Classification: A61K,A61P

Abstract:
A method of inhibiting cancer growth in a mammal, comprising administering to the mammal a cancer-inhibitory amount of a tetracycline compound selected from the group consisting of:4-de(dimethylamino)tetracycline (CMT-1),4-de(dimethylamino)-7-chlorotetracycline (CMT-4),4-hydroxy-4-de(dimethylamino)tetracycline (CMT-6),4-de(dimethylamino)-12.alpha.-deoxytetracycline (CMT-7), and6.alpha.-deoxy-5-hydroxy-4-de(dimethylamino)tetracycline (CMT-8);wherein said cancer is selected from the group consisting of prostate, breast, colon, lung melanoma and lymph cancers.