Patent ID: 6362211
Filing Date: 2002-03-26
Classification: A61P,C07D

Abstract:
A compound of formula (I): or a pharmaceutically acceptable ester or salt thereof, wherein,â€”Aâ€” forms, together with the two carbon atoms to which it is attached, a ring system being a partially or fully saturated monocyclic carbocyclic ring of 3 to 7 ring atoms or a partially or fully saturated bicyclic bridged carbocyclic ring of 6 to 10 ring atoms, wherein each of the said ring systems formed by â€”Aâ€” is optionally fused with a benzene ring that is optionally substituted with one to three substituent(s) R1; each R1 is independently halogen, OH, NH2, (C1-6)alkyl, (C2-6)alkenyl, (C2-6)alkynyl, (C1-6)alkoxy, halo-(C1-6)alkyl, OHâ€”(C1-6)alkyl, mono- or di(C1-6)alkylamino or OHâ€”(C1-6)alkoxy(C1-6)alkoxy; each R2 is independently halogen, OH, &boxH;O, &boxH;CH2, NH2, (C1-6)alkyl, (C2-6)alkenyl, (C1-6)alkoxy, halo-(C1-6)alkyl, OHâ€”(C1-6)alkyl, NH2â€”(C1-6)alkyl or mono- or di(C1-6)alkylamino; R3 is H, F, OH, &boxH;O, &boxH;CH2, (C1-6)alkyl, (C2-6)alkenyl, (C2-6)alkynyl, (C1-6)alkoxy, halo-(C1-6)alkyl, NH2 or mono- or di(C1-6)alkylamino; m is 0, 1, 2 or 3; and t is 0, 1, 2 or 3.