Patent ID: 9040060
Filing Date: 2015-05-26
Classification: A61K,C08G,C08L

Abstract:
1. An in-vivo gel-forming composition comprising: (i) a polymer having the formula: wherein: n is an integer of from about 5 to about 500, q and r are integers each independently ranging from about 2 to about 2,000, m is an integer ranging from 1 to about 5, R R R X and Y are each independently selected from the group consisting of H, alkyl, alkenyl and aryl, and (ii) a PEGylated antibody, in aqueous solution, wherein the polymer is not covalently crosslinked and is present at a concentration of from about 5% by weight to about 8% by weight, and the composition (i) is a liquid at ambient temperatures and (ii) forms a hydrolytically degradable gel at body temperature (37° C.).