Patent ID: 6207709
Filing Date: 2001-03-27
Classification: A61P,C07C

Abstract:
A compound of the formula (Ia) ##STR6##whereineach of the groups X and Y is, independently, hydrogen; halogen; nitro; C.sub.1 -C.sub.6 alkyl; C.sub.2 -C.sub.4 alkenyl; C.sub.2 -C.sub.4 alkynyl; C.sub.1 -C.sub.6 alkoxy; C.sub.1 -C.sub.6 alkylthio; SOR.sub.2 or SO.sub.2 R.sub.2 in which R.sub.2 is C.sub.1 -C.sub.6 alkyl, phenyl or benzyl; or SO.sub.2 N(R.sub.3).sub.2 in which each of the groups R.sub.3 is, independently, hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.4 alkenyl, C.sub.2 -C.sub.4 alkynyl, phenyl or benzyl;R is hydroxy; --OR.sub.5 in which R.sub.5 is C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.4 alkenyl, C.sub.2 -C.sub.4 alkynyl or benzyl; --N(R.sub.3).sub.2 or --N(R.sub.3)OR.sub.3 in which each of R.sub.3 is as defined above;W is --SO.sub.2 R.sub.4 in which R.sub.4 is C.sub.1 -C.sub.6 alkyl, an optionally substituted C.sub.2 -C.sub.4 alkenyl, an optionally substituted phenyl or benzyl; --CONHR.sub.5 or --CSNHR.sub.5 in which R.sub.5 is as defined above; or a pharmaceutically acceptable salt thereof.