Patent ID: 6739531
Filing Date: 2004-05-25
Classification: C12M,C12N,G01N

Abstract:
A method for disrupting cells or viruses, the method comprising the steps of:a) holding a liquid or gel containing the cells or viruses in the chamber of a container, wherein the container includes at least one wall defining the chamber, and wherein the wall has a surface external to the chamber; b) coupling a transducer device to the external surface of the wall with a preload force sufficient to create a stress within the wall; and c) operating the transducer device at a frequency and amplitude sufficient to generate pressure waves or pressure pulses in the chamber; wherein the natural frequency of the wall, when the wall is stressed by the preload force, is equal to the operating frequency of the transducer device or differs from the operating frequency of the transducer device by less than 50% of the operating frequency of the transducer device.