Patent ID: 7262290
Filing Date: 2007-08-28
Classification: C12Q,G01N

Abstract:
1. A diagnostic marker for predicting susceptibility of an individual to having or developing idiopathic generalized epilepsy, juvenile absence epilepsy, childhood absence epilepsy, or temporal lobe epilepsy comprising an isolated human KIR 4.1 nucleic acid molecule of SEQ ID NO:1 or a human KIR 4.1 polypeptide of SEQ ID NO:2, wherein the thymine at position 1037 of the human KIR 4.1 nucleic acid molecule of SEQ ID NO:1 is replaced with cytosine, or the cysteine at position 271 of the human KIR 4.1 polypeptide of SEQ ID NO:2 is replaced with an arginine.