Patent ID: 6083701
Filing Date: 2000-07-04
Classification: C12Q

Abstract:
A method of analysing a nucleic acid target comprising a tandem repeat sequence and two flanking sequences, which method comprises providing at least two unlabelled nucleic acid probes in an array, each probe immobilised on a surface of a support and comprising a tandem repeat sequence and two flanking sequences complementary to the tandem repeat sequence and the two flanking sequences of the target, each probe immobilised at a spaced location on the surface of the support, the tandem repeat sequence length of one probe being different from that of another probe, labelling the target, applying the labelled target to the surface, subjecting the surface to a high stringency wash to remove labelled target that has not formed a perfectly matched hybrid with a probe, and using the label to observe a perfectly matched hybrid on said array where the tandem repeat sequence of the target is the same length as the tandem repeat sequence of a probe.