Patent ID: 6197969
Filing Date: 2001-03-06
Classification: C07D

Abstract:
A process for producing a substituted alkylamine represented by formula (3): ##STR14##(wherein X is a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group, a cyano group or a nitro group; n is an integer of 1 to 4; and R.sup.1 and R.sup.2 are each independently a hydrogen atom or an alkyl group which may be substituted with phenyl group, and may together form a 5- or 6-membered ring) or a salt thereof, which process comprises reacting a 2-aminothiophenol derivative metal salt represented by formula (1): ##STR15##(wherein M is a bivalent metal atom; X has the same definition as given above; and n has the same definition as given above) with an amino acid-N-carboxy anhydride represented by formula (2): ##STR16##(wherein R.sup.1 and R.sup.2 have the same definitions as given above) and then subjecting the reaction product to cyclization under an acidic condition.