Patent ID: 6531129
Filing Date: 2003-03-11
Classification: A61K,A61M,A61P,C07K,C12N,C12Q,C12Y,G01N,Y10S

Abstract:
A method of detecting the presence, absence or level of a heparanase protein in a biological sample, the heparanase protein being specifically recognized by an anti-heparanase antibody, the anti-heparanase antibody being capable of binding a polypeptide as set forth in SEQ ID NO:2, the method comprising:(a) extracting proteins from the biological sample, thereby obtaining a plurality of proteins; (b) size separating said proteins; (c) interacting said size separated proteins with the anti-heparanase antibody being capable of binding the polypeptide as set forth in SEQ ID NO:2; and (d) detecting the presence, absence or level of said interacted anti-heparanase antibody, thereby detecting the presence, absence or level of the heparanase protein in the biological sample.