Patent ID: 6335349
Filing Date: 2002-01-01
Classification: A61K,A61P,C07D,Y10S

Abstract:
A compound selected from the group consisting of(a) a substantially chirally pure (R)-enantiomer, a substantially chirally pure (S)-enantiomer, or a mixture of the (R)- and (S)-enantiomers of a 2-(2,6-dioxopiperidin-3-yl)-isoindoline of the formula: â€ƒin which: Y is C&boxH;O or CH2; one of R1, R2, R3, and R4 is â€”NHR5 and the remaining of R1, R2, R3, and R4 are hydrogen; R5 is hydrogen and R6 is alkyl of 1 to 8 carbon atoms, benzyl, or halo, or R5 is alkyl of 1 to 8 carbon atoms and R6 is hydrogen, alkyl of 1 to 8 carbon atoms, benzyl, or halo; and (b) the acid addition salts of said 2-(2,6-dioxopiperidin-3-yl)-isoindoline.