Patent ID: 8524703
Filing Date: 2013-09-03
Classification: A61P,C07D

Abstract:
1. A compound of formula (I-a): or a pharmaceutically acceptable salt thereof, wherein a is a single or double bond; X is O, S, S(O), S(O) L is —[C(R X and L taken together are a bond; Q is substituted or unsubstituted monocyclic aryl, substituted or unsubstituted bicyclic aryl, substituted or unsubstituted monocyclic heteroaryl, or substituted or unsubstituted bicyclic heteroaryl; R R R p is 1, 2, 3, 4, or 5; q1 and q2 are independently 0, 1, 2, or 3, provided that the sum of q1 and q2 is 0, 1, 2, or 3; r1 and r2 are independently 0, 1, 2, or 3, provided that the sum of r1 and r2 is 0, 1, 2, or 3; s is 0, 1 or 2; and t is 0 or 1; wherein Q, when substituted, is independently substituted with 1, 2, 3, 4, or 5 substituents, wherein the substituent is halogen, cyano, C