Patent ID: 7635683
Filing Date: 2009-12-22
Classification: A61K,C07K

Abstract:
1. A compound of Formula I: Wherein A is selected from —(C═O)—O—R (i) aryl; substituted aryl; heteroaryl; substituted heteroaryl; (ii) heterocycloalkyl or substituted heterocycloalkyl; (iii) —C R (i) hydrogen; (ii) aryl; substituted aryl; heteroaryl; substituted heteroaryl; (iii) heterocycloalkyl or substituted heterocycloalkyl; (iv) —C R and R′ are independently selected from the group consisting of: (i) —C (ii) aryl; substituted aryl; heteroaryl; substituted heteroaryl; (iii) heterocycloalkyl or substituted heterocycloalkyl; (iv) hydrogen; deuterium; G is selected from —OH, —NHS(O) R (i) aryl; substituted aryl; heteroaryl; substituted heteroaryl (ii) heterocycloalkyl or substituted heterocycloalkyl; (iii) —C R (i) hydrogen; (ii) aryl; substituted aryl; heteroaryl; substituted heteroaryl; (iii) heterocycloalkyl or substituted heterocycloalkyl; (iv) —C X and Y taken together with the carbon atoms to which they are attached form a cyclic moiety which selected from aryl, substituted aryl, heteroaryl, or substituted heteroaryl; W is absent, or selected from —O—, —S—, —NH—, —N(Me)—, —C(O)NH—, or —C(O)N(Me)—; Z is selected from the groups consisting of: W-Z taken together, is —CN, —N