Patent ID: 6767916
Filing Date: 2004-07-27
Classification: A61K,A61P,C07D

Abstract:
A compound of Formula (I): or a pharmaceutically acceptable salt or solvate thereof wherein:Ar represents: pyridyl which may be unsubstituted or substituted with one or more substituents selected from the group consisting of: (a) Cl, (b) Br, (c) F, (d) OH, (e) NO2, (f) Cr3, (g) C1-4 alkyl, (h) SCH3, (i) NHCOCH3, (j) N(R6)(R8) wherein R6 and R8 are the same or different and each represents H or C1-4 alkyl, (k) OR10 wherein R10 represent a saturated or unsaturated C1-6 straight or branched hydrocarbyl group which may be unsubstituted or substituted with from 1 to 3 substituents selected from Cl, Br, F, OMe, NO2 and CF3, and (l) â€”OCOR11 wherein R11 represents a saturated or unsaturated C1-6 straight or branched hydrocarbyl group or a phenyl group; R represents OH, OR10 or OCOR11 wherein R10 and R11 are as defined above; and R1 represents H or a C1-6 straight or branched hydrocarbyl group which may be unsubstituted or substituted with from 1 to 3 substituents selected from Cl, Br, F, OMe, NO2 and CF3; with the proviso that when R1 is CH3 and R is OH, then Ar cannot be 3-pyridyl or 4-pyridyl.