Patent ID: 7585864
Filing Date: 2009-09-08
Classification: A61P,C07D

Abstract:
1. A compound of the formula: or the pharmaceutically acceptable salts thereof, wherein: one of a, b, c and d represents N or N each of a, b, c, and d are independently selected from the group consisting of: CR each R R R R R X represents N, CH or C, and when X is C the optional bond (represented by the dotted line) to carbon atom 11 is present, and when X is CH the optional bond (represented by the dotted line) to carbon atom 11 is absent; Z is —O—; R said R Y represents —CH n is 0 to 6; Q represents —O— or —N—, provided that Q is not adjacent to a heteroatom in the heterocycloalkyl rings of 2.1, 3.1, 4.1, 5.1, 6.1 and 7.1; R R wherein R the imidazolyl ring 9.0 and optionally being substituted with one or two substituents, said imidazole ring 10.0 optionally being substituted with 1-3 substituents, and said pyridyl ring 9.1 optionally being substituted with 1-4 substituents, wherein said optional substituents for rings 9.0, 9.1, 10.0 and 11.0 are bound to the carbon atoms of said rings and are independently selected from the group consisting of: —NHC(O)R 15 , —C(R 18 ) 2 OR 19 , —OR 15 , —SR 15 , F, Cl, Br, alkyl, substituted alkyl (as defined above in (b)), aryl, arylalkyl, cycloalkyl, or —N(R 15 ) 2 ; R 15 is as defined above; each R 18 is independently selected from the group consisting of: H and alkyl; R 19 is selected from the group consisting of: H and —C(O)NHR 20 , and R 20 is as defined below; R R R R when R R R