Patent ID: 7910551
Filing Date: 2011-03-22
Classification: A61P,C07K

Abstract:
1. A method for treating a C35-expressing cancer in a mammalian subject which comprises administering to said subject a therapeutically effective amount of a pharmaceutical composition, wherein said composition comprises one or more isolated C35 peptides consisting of an epitope selected from the group consisting of: amino acids S-9 to V-17 of SEQ ID NO:2, amino acids V-10 to V-17 of SEQ ID NO:2, amino acids E-16 to V-23 of SEQ ID NO:2, amino acids E-16 to R-24 of SEQ ID NO:2, amino acids E-16 to I-25 of SEQ ID NO:2, amino acids S-21 to F- 3 5 of SEQ ID NO:2, amino acids C-30 to T-38 of SEQ ID NO:2, amino acids E-31 to Y-39 of SEQ ID NO:2, amino acids E-36 to A-43 of SEQ ID NO:2, amino acids A-37 to A-45 of SEQ ID NO:2, amino acids A-37 to V-46 of SEQ ID NO:2, amino acids Y-39 to V-46 of SEQ ID NO:2, amino acids S-44 to I-53 of SEQ ID NO:2, amino acids A-45 to I-53;of SEQ ID NO:2, amino acids G-52 to L-59 of SEQ ID NO:2, amino acids E-54 to T-62 of SEQ ID NO:2, amino acids S-57 to F-75 of SEQ ID NO:2, amino acids R-58 to I-67 of SEQ ID NO:2, amino acids G-61 to I-69 of SEQ ID NO:2, amino acids G-63 to F-83 of SEQ ID NO:2, amino acids E-66 to L-73 of SEQ ID NO:2, amino acids E-66 to V-74 of SEQ ID NO:2, amino acids F-83 to E-103 of SEQ ID NO:2, amino acids D-88 to A-96 of SEQ ID NO:2, amino acids L-89 to A-96 of SEQ ID NO:2, amino acids A-92 to T-101 of SEQ ID NO:2, amino acids R-95 to L-102 of SEQ ID NO:2, amino acids A-96 to K-104 of SEQ ID NO:2, amino acids K-104 to V-113 of SEQ ID NO:2, amino acids I-105 to V-113 of SEQ ID NO:2, and amino acids I-105 to I-114 of SEQ ID NO:2, thereby treating said C35-expressing cancer.