Patent ID: 7205293
Filing Date: 2007-04-17
Classification: A61P,C07D

Abstract:
1. A compound of the formula I wherein: R 1 is selected from: (1) hydrogen, (2) —C (3) phenyl or heterocycle, which is unsubstituted or substituted with 1–5 substituents where the substituents are independently selected from: (4) —C R 2a , R 2b and R 2c are independently selected from: (1) hydrogen, (2) —C (3) halo, (4) hydroxy, (5) —O—C (6) —OCF (7) trifluoromethyl, (8) —CO (9) —CONR (10) —SO R 3 is selected from: (1) hydrogen, (2) —C (3) phenyl or heterocycle, which is unsubstituted or substituted with 1–5 substituents where the substituents are independently selected from: R 4 is selected from: (1) hydrogen, (2) C (3) C (4) benzyl , and (5) phenyl; R 6 is selected from: (1) hydrogen, (2) —C (3) phenyl or heterocycle, which is unsubstituted or substituted with 1–5 substituents where the substituents are independently selected from: X is a bond or is —N(R 4a )—, where R 4a is independently selected from the definitions of R 4 ; m is 1 or 2; n is 1 or 2; or a pharmaceutically acceptable salt or diastereomer thereof.