Patent ID: 6096315
Filing Date: 2000-08-01
Classification: A61K,C07K,C12N,G01N,Y10S

Abstract:
An immunomodulatory composition effective for the prevention or treatment of disease comprising:(A) a pharmaceutically effective amount of an immunomodulatory compound comprisingat least a first peptide for modulating T cell activity which is a Portion of a polypeptide molecule selected from the group consisting of a non-polymorphic region of MHC Class I, a non-polymorphic region of MHC Class II, lymphocyte function associated molecule-3, antibodies to CD-2, antibodies to CD-3, antibodies to CD-4, antibodies to CD-8, lectins, lymphoklines, and portion of the Fc region of the heavy chain of immunoglobulins,and at least a second peptide which is an antigenic peptide associated with disease or a causative agent of disease,each of the first and second peptides being a portion of a different polypeptide and each comprising up to about 35% of the total number of amino acids of the polypeptide, and being covalently linked together, and,(B) a pharmaceutically acceptable carrier or diluent.