Patent ID: 6124100
Filing Date: 2000-09-26
Classification: C12Q,Y10S

Abstract:
A diagnostic method for detecting spinocerebellar ataxia type III (""SCA III III"") syndrome, comprising the steps of:attaching a portion (SEQ ID NO: 3) of a spinocerebellar ataxia type III (""SCA III"") gene containing copies of 73 trinucleotide (CAG) repeat units to a substrate;amplifying a DNA segment containing copies of the trinucleotide repeat units from the genomic DNA of a testee using two labeled primers (SEQ ID NO: 1 and SEQ ID. NO: 2) using a polymerase chain reaction (PCR) to produce a PCR product;hybridizing the SCA III gene with the PCR product; andanalyzing the results of the hybridization.