Patent ID: 6177575
Filing Date: 2001-01-23
Classification: C07D

Abstract:
A process for the manufacture of an imidazole, comprising, reacting at a temperature of -20.degree. C. to +50.degree. C. in the liquid phase:(a) ammonium carbonate or ammonium bicarbonate;(b) a glyoxal of the formula ##STR6##(c) an aldehyde of formula R.sup.3 CHO (II); and(d) in the absence or the presence of an amine of the formula R.sup.4 NH.sub.2 (III);wherein:R.sup.1, R.sup.2 and R.sup.3 are each independently hydrogen, hydrocarbyl or substituted hydrocarbyl;R.sup.4 is hydrogen, alkyl, or substituted alkyl;and provided that (a), (b), (c) and (d) are added substantially simultaneously to said process.