Patent ID: 6057476
Filing Date: 2000-05-02
Classification: C07C,C07D

Abstract:
A process for preparation of an 3-amino-2-hydroxy-1-propyl ether of the formula ##STR5## wherein R.sup.1 is substituted or unsubstituted alkyl, substituted or unsubstituted aryl or substituted, or unsubstituted heterocyclic ring, R.sup.2 and R.sup.3 are the same or different hydrogen atom, a substituted or unsubstituted alkyl, or may form a ring together with an adjacent nitrogen atom, which ring may be interrupted with a nitrogen atom, an oxygen atom or a sulfur atom,which is characterized in reacting an epoxy compound of the formula ##STR6## wherein X is halogen or sulfonyloxy group, with an alcohol of the formulaR.sup.1 OH (2)wherein R.sup.1 is as defined above,in the presence of a fluoride salt to prepare and then, reacting an amine of the formulaHNR.sup.2 R.sup.3 ( 3)wherein R.sup.2 and R.sup.3 are same as defined above.