Patent ID: 7473528
Filing Date: 2009-01-06
Classification: C12Q

Abstract:
1. A method for indicating Chagas disease in a human test subject, said method comprising: a) quantifying a level of RNA encoded by a CDC14 cell division cycle 14 homolog A ( b) comparing said level of RNA in said sample of said test subject with a quantified level of control RNA encoded by said gene in blood samples of control subjects which are classified as healthy control subjects; and c) comparing said level of RNA in said sample of said test subject with a quantified level of control RNA encoded by said gene in blood samples of control subjects which are classified as having Chagas disease; wherein a statistically significant determination with a p value less than 0.05 resulting from steps (b) and (c) that expression of said gene in said sample of said test subject is higher with a fold-change of at least 1.5 relative to said samples of said control subjects classified as healthy control subjects, and is similar relative to said samples of said control subjects classified as having Chagas disease, is indicative of Chagas disease in said human test subject.