Patent ID: 7294745
Filing Date: 2007-11-13
Classification: C07C

Abstract:
1. Process for preparing an aldol derivative from the corresponding alkene in a single step using a eco-friendly multi-functional catalyst system, the process comprising: (a) contacting carbon monoxide, hydrogen and an alkene with a catalyst system consisting of a metal complex comprising hydridocarbonyltris(triphenylphosphine) rhodium(I) and a solid base, in a solvent under hydroformylation and subsequently aldol condensation conditions to obtain a product stream; (b) cooling the product stream obtained in step (a) and separating the aldol derivative so obtained, wherein the hydridocarbonyltris(triphenylphosphine) rhodium(I) is contacted first with the solid base and degassed under an inert atmosphere and the mixture stirred for 25 to 35 hours at a temperature in the range of 20 to 30° C. to impregnate the metal complex onto the base such that the magnesium to aluminum ratio in the base is in the range of 1.5 to 3.5.