Patent ID: 7122204
Filing Date: 2006-10-17
Classification: A61K

Abstract:
1. A once-a-day antibiotic composition comprising: a mixture of at least four dosage forms, two of said dosage forms each comprising at least one antibiotic with a beta-lactam ring or portion thereof and a pharmaceutically acceptable carrier; and two of said dosage forms each comprising at least one beta-lactamase inhibitor and a pharmaceutically acceptable carrier; each of said four dosage forms initiating release of said antibiotic or of said inhibitor at different times, whereby Cmax in serum for both the total amount of antibiotic and the total amount of inhibitor is acheived in no more than about twelve hours after administration, and said once-a-day antibiotic composition contains a therapeutically effective amount of said at least one antibiotic, said therapeutically effective amount being the total dosage of said at least one antibiotic for a twenty four hour period.