Patent ID: 6596278
Filing Date: 2003-07-22
Classification: A61K

Abstract:
A method for potentiation of the immunological response of humans and animals to at least one cytotoxic T-lymphocyte (CTL) antigen, comprising:dispersing the cytotoxic T-lymphocyte (CTL) antigen in a solution comprising at least one biocompatible biopolymer to form a dispersion; forming a spherical microparticle comprising the antigen embedded therein; suspending the spherical microparticles comprising the antigen in a carrier medium; and parenterally administering the preparation thus obtained to a human or animal in need thereof in order to initiate, potentiate and prolong a cytotoxic T-lymphocyte response, wherein said antigen induces a negligible and non-protective immune response if administered as aqueous solution.