Patent ID: 8058023
Filing Date: 2011-11-15
Classification: A61K,A61P,C12Q,G01N

Abstract:
1. A method comprising: obtaining a blood sample from a patient undergoing platelet inhibitor therapy and having or suspected of having vascular disease; assessing platelet function by assessing platelet reactivity, time-to-thrombin formation (TTF), or time-to-fibrin formation (TFF) in the blood sample in response to an agonist, wherein assessing platelet reactivity is by a method other than assessing GP IIb/IIIa receptor expression, said assessing platelet function providing a test score, wherein the test score is independent of a pre-treatment baseline of platelet reactivity in the patient; inputting the test score into a computer programmed to execute an algorithm that compares the test score to a risk threshold score and determines whether the test score is greater than a risk threshold score based on a population study, wherein a test score greater than the risk threshold score indicates the patient is at risk of a thrombotic event, said inputting generating a result from execution of the algorithm; and generating a report providing the result, wherein the report indicates a risk of a thrombotic event in the patient.