Patent ID: 9107931
Filing Date: 2015-08-18
Classification: A61K,A61Q,C07C,C07D,C12N

Abstract:
1. A cationic amphipathic compound of formula (I): in which: in which: E represents a linear or branched hydrocarbon group which can comprise from 1 to 15 carbon atoms, and which can optionally comprise one or more heteroatoms; m is 1; AA represents an amino acid radical; n is an integer equal to 0 or 1; W L represents an ester (CO—O—), disulfide (—S—S—), vinyl ether (—O—C═C—), acylhydrazone (CO—NR—N═CR′R″) group; p is an integer equal to 0 or 1; Y is a branched hydrocarbon group which can comprise from 1 to 20 carbon atoms, and/or one or more heteroatoms, and which can optionally be covalently coupled with the W q is an integer comprised between 0 and 8; Z represents a basic amino acid; r is an integer comprised between 1 and 16, it being understood that if q is equal to 1 then r is at least equal to 2 and that if r is greater than 1, then the Z groups can be identical or different; and s is an integer equal to 1 or 2; and physiologically acceptable addition salts thereof.