Patent ID: 7615227
Filing Date: 2009-11-10
Classification: A61K,A61P,C12N

Abstract:
1. A method of inducing neovascularization in a tissue, comprising introducing a CpG oligodeoxynucleotide into an area of the tissue wherein the formation of new blood vessels is desired, wherein the CpG oligodeoxynucleotide has a sequence as set forth as: wherein at least one nucleotide separates consecutive CpGs; D is adenine, guanine, or thymidine; Y is cytosine or thymine, N is any nucleotide and N wherein at least one nucleotide separates consecutive CpGs; RD is selected from the group consisting of GpT, GpG, GpA, ApT and ApA; YT is selected from the group consisting of TpT or CpT; N is any nucleotide and N wherein the CpG oligodeoxynucleotide is 8 to 30 nucleotides in length,