Patent ID: 8999336
Filing Date: 2015-04-07
Classification: A61K,A61P,C07K,C12N,G01N

Abstract:
1. A substantially pure polypeptide comprising a fully human or humanized chimpanzee monoclonal antibody that binds A33 antigen, wherein said monoclonal antibody comprises a heavy chain CDR1 region having the amino acid sequence of SEQ ID NO:67, a heavy chain CDR2 region having the amino acid sequence of SEQ ID NO:69, a heavy chain CDR3 region having the amino acid sequence of SEQ ID NO:71, a light chain CDR1 region having the amino acid sequence of SEQ ID NO:75, a light chain CDR2 region having the amino acid sequence of SEQ ID NO:77 and a light chain CDR3 region having the amino acid sequence of SEQ ID NO:79.