Patent ID: 8818733
Filing Date: 2014-08-26
Classification: A61B,A61N

Abstract:
1. A method comprising: illuminating target tissue of a patient containing a concentration of a photosensitizer with one or more wavelengths suitable for fluorescence excitation of the photosensitizer; detecting total emissions from the target tissue over a wavelength range of interest, the emissions including autofluorescence emissions of the target tissue and fluorescence emissions of the photosensitizer; determining the autofluorescence of the target tissue; generating a corrected photosensitizer emission by subtracting the autofluorescence emission from the total emissions from the target tissue; determining a photosensitizer content ratio based on the corrected photosensitizer emission and the autofluorescence of the target tissue; and determining the concentration of the photosensitizer in the target tissue based on the photosensitizer content ratio.