Patent ID: 7875613
Filing Date: 2011-01-25
Classification: A61P,C07D

Abstract:
1. A compound having a formula: wherein : T, U, W, X are the same or different and are chosen from C or N; V is N; Y is N-OR1, NR′1, CR2R′2; R1 is H, Alkyl, Alkenyl, Alkoxyalkyl, Aryloxyalkyl, Arylalkyl, Alkoxycarbonylalkyl, Carboxyalkyl; R′1 is H, Alkyl, Aryl or Aralkyl; R2, R′2 are each the same or different and are independently selected from H, Alkyl, Aryl or Aralkyl; Rv is absent; Rw is either H or absent; Ru is absent or is chosen from the group consisting of H, CN, ═O, Hal, Alk, OAlk, OH, NRCN, C(CN)═C(OH)(OAlk), SR, NRR′, C(O)NRR′, Heterocycle, Aryl, Heteroaryl, Cycloalkyl, where Alk, Aryl, Heteroaryl, Heterocycle, Cycloalkyl are optionally substituted by Hal, NRR′, CN, OH, CF R3, R4, R5, R6 are each identical or different and are independently chosen from the group consisting of H, OAlk, Alk, Hal, NRR′, CN, OH, OCF R and R′ are each identical or different and are independently chosen from the group consisting of H, Alk, wherein Alk is optionally substituted by Hal, NRR′, CN, OH, CF or their pharmaceutically acceptable salts, or their optical isomers, racemates, diastereomers or enantiomers, or their regioisomers, geometrical isomers (E and Z) or mixtures thereof.