Patent ID: 8932579
Filing Date: 2015-01-13
Classification: A23L,A23V,A61K,A61P

Abstract:
1. A topical composition comprising rosmarinic acid in combination with hydrolysis effective amounts of a probiotic microorganism containing or producing a hydrolytic enzyme of an esterase so that the rosmarinic acid is hydrolyzed to provide caffeic acid and 3,4-dihydroxy phenyllactic acid in the composition in amounts sufficient to provide an inhibitory effect on the expression of matrix metalloproteinase-1 compared to non-hydrolysed rosmarinic acid containing compositions when the composition is applied to skin; wherein the composition is in the form of an aqueous, aqueous-alcoholic or oily solution, a dispersion of the solution, lotion, or serum type, an emulsion that has a liquid or semi-liquid consistency, obtained by dispersion of a fatty phase in an aqueous phase (O/W) or vice-versa (W/O), or a suspension or emulsion that has a soft, semi-solid or solid consistency, microcapsules, microparticles or vesicular dispersions, wherein the topical composition is useful for treating skin damage.