Patent ID: 6495557
Filing Date: 2002-12-17
Classification: A61P,C07D

Abstract:
Compounds of the formula I in whichR1, R2 independently of one another are each H, A, OA or Hal, R1 and R2 together are also alkylene having 3-5 carbon atoms, â€”Oâ€”CH2â€”CH2â€”, â€”CH2â€”Oâ€”CH2â€”, â€”Oâ€”CH2â€”Oâ€” or â€”Oâ€”CH2â€”CH2â€”Oâ€”, X is R5, R6 or R4 which is monosubstituted by R7, R4 is linear or branched alkylene having 1-10 carbon atoms, in which one or two CH2 groups may be replaced by â€”CH&boxH;CHâ€” groups, R5 is cycloalkyl or cycloalkylalkylene having 5-12 carbon atoms, R6 is phenyl or phenylmethyl, R7 is COOH, COOA, CONH2, CONHA, CON(A)2 or CN, A is alkyl having 1 to 6 carbon atoms and Hal is F, Cl, Br or I, and their physiologically acceptable salts.