Patent ID: 6127169
Filing Date: 2000-10-03
Classification: A61K,A61P,C07K

Abstract:
An isolated substantially pure non-agglutinating .beta.-galactoside binding protein which is capable of inhibiting the growth of vertebrate cells, said protein being a monomer that is free of the dimeric form and that comprises an amino acid sequence selected from the group consisting of:(a) the amino acid sequence of SEQ ID NO: 18;(b) the amino acid sequence of SEQ ID NO: 20;(c) an amino acid sequence consisting of amino acids 2 to 135 of SEQ ID NO: 18 or SEQ ID NO: 20; and(d) an amino acid sequence which differs from the amino acid sequence of (a), (b) or (c) by having one or more amino acid residues from the region of amino acid position 63 to amino acid position 76 substituted by a different amino acid.