Patent ID: 8728440
Filing Date: 2014-05-20
Classification: A61K,B82Y,C07F,Y10T

Abstract:
1. A nanoparticle composition comprising nanoparticles having idealized structure II, the nanoparticles comprising a functionalized nanoparticulate metal oxide and a positively charged trioxysilane ligand wherein R 2 is independently at each occurrence a C 1 -C 3 alkyl group; R 3 is independently at each occurrence a hydrogen or a C 1 -C 3 aliphatic group; R 4 is a C 1 -C 5 aliphatic radical, a C 7 -C 12 aromatic radical, or a C 5 -C 10 cycloaliphatic group; n is 0, 1, 2 or 3; q is 1, 2 or 3; X − represents a charge balancing counterion; and the functionalized nanoparticulate metal oxide comprises nanoparticulate tantalum oxide.