Patent ID: 6887995
Filing Date: 2005-05-03
Classification: C07C,C07D

Abstract:
1. A novel process for preparing a compound of formula I or a salt thereof, which comprises reacting a N-aryl —O-alkylcarbamate of formula II or a salt thereof, with a compound of formula III or a salt thereof, in the presence of a lithium cation, a base and a nucleophile, wherein X and Y are independently H or F; W1 is Cl, Br, or —OS(O) W2 is H or —C(O)—R R is aryl or alkyl, the alkyl optionally being substituted by one or more F, Cl, Br, or I; R R Q is structure ii: Z R R R R aryl is phenyl, pyridyl or napthyl; at each occurance, aryl or phenyl may be optionally substituted with one or more F, Cl, Br, I, CN, OH, SH, C het is 5- to 10-membered heterocyclic rings having one or more oxygen, nitrogen, and sulfur atoms; his 1,2,3, or 4; i is 0 or 1; and m is 0 or 1.