Patent ID: 6515023
Filing Date: 2003-02-04
Classification: C07B,C07C,C07D

Abstract:
A compound of the formula or a pharmaceutically acceptable salt thereof, wherein A is hydrogen or R1 is hydrogen or C1-10 alkyl;Ar is X isOH, OCH3, OC(O)C(CH3)3, OC(O)CH3, OCH2CH3;R2 is CH(CH3)2, C(CH3)3, CH3, CH2CH3, CH2CH2CH3,CH(CH3)2CH2CH3, CH(CH3)CH2CH3, CH(CH2CH3)2, CH(CH3)CH2OCH3, CH(CH3)CH2CH2CH3, CH(CH3)CH2F, or CH(CH3)CH2SCH3; A1 is hydrogen, Cl, F, CH3, or CN; A2 is hydrogen, F, or OCH3; A3 and A4 are hydrogen; m is 0, 1, or 2; B is hydrogen; R6 is CH(CH3)2, CH2CH3, CH3,C(CH3)3, CH2Ph, Ph, C(CH3)2NC(O)OC(CH3)3, C(NH2)(CH3)2,