Patent ID: 7601714
Filing Date: 2009-10-13
Classification: A61P,C07D

Abstract:
1. A compound of the following formula (I): X is C (A) oxo, (B) C (C) C (D) C (E) aryl (F) —COR (G) halogen, (H) —NR Y is —NH—, —O— or —S—; R 1 is: (A) aryl or heteroaryl, each optionally and independently substituted with one or more of the following groups: (B) C (C) —COR (D) is: which is optionally substituted with halogen; (E) is selected from the following: R 2 is selected from the following groups: (A) CF (B) cyano, (C) halogen, (D) nitro, (E) C (F) arylalkynyl which is optionally substituted with one or more of the following groups: R 3 is selected from the following groups: R 4 and R 5 are each independently selected from: (A) hydrogen, (B) C (C) C (D) arylsulfonyl, (E) aryl-C (F) heteroarylsulfonyl, (G) C (H) arylcarbonyl, (I) aryl-C (J) heteroarylcarbonyl, (K) C (L) heteroaryl, or wherein R (A) C (B) C (C) C (D) C (E) halogen, (F) —NR (G) —COR (H) —OR (I) oxo, or wherein NR or a tautomer or pharmaceutically acceptable salt thereof or a corresponding compound having at least one amine group protected by an amino-protecting group.