Patent ID: 7409296
Filing Date: 2008-08-05
Classification: G01N,G16B,Y10T

Abstract:
1. A method for scoring a match of two peptides, the method comprising: providing information associated with an experimental peptide, where the information comprises at least mass spectrum information associated with the experimental peptide and at least one fragment of the experimental peptide; providing information associated with a candidate peptide; defining an extended match E based on the information associated with the experimental peptide and the information associated with the candidate peptide, the extended match E being a probabilistic function of a tuple of random variables that include at least a fragment match and a peptide match between the experimental peptide and the candidate peptide; generating a stochastic model based on the information associated with the experimental peptide and the information associated with the candidate peptide, the stochastic model incorporating a probability distribution of each of the random variables; scoring the extended match E based on a likelihood ratio  where outputting, in a user readable format, a result of the step of scoring the extended match E.