Patent ID: 8548545
Filing Date: 2013-10-01
Classification: A61B

Abstract:
1. A method for measuring a concentration of a biogenic substance contained in a living body, the method comprising steps of: a step (a) of preparing a measuring device, wherein the measuring device comprises a light source, an optical filter, and a light receiver, a step (b) of irradiating a substantially-parallel light from the light source onto a particle chip implanted in a skin though a position on the surface of the skin to generate a first reflected light, wherein the particle chip comprises a substrate and a plurality of metal particles, a step (c) of receiving the first reflected light by the light receiver through the optical filter to obtain a first signal Xa, wherein the following equation is satisfied: lambda lambda B: Raman shift proper to the biogenic substance a step (d) of inclining the light source, a step (e) of irradiating the position identical to said position with the substantially-parallel light in such a manner that the particle chip is not irradiated with the substantially-parallel light so as to obtain a second reflected light, a step (f) of receiving the second reflected light by the light receiver through the optical filter to obtain a second signal Xb, and a step (g) of calculating the concentration of the biogenic substance on the basis of the difference between the first signal Xa and the second signal Xb.