Patent ID: 6413987
Filing Date: 2002-07-02
Classification: A61K,A61P,C07D,Y10S

Abstract:
A compound having the formula or an optically active isomer thereof, wherein n is equal to 1, 2, or 3, A represents an aromatic substituent such as phenyl or substituted phenyl, Z represents two hydrogen atoms or an oxygen atom, the (CH2)n group having a straight or branched chain, B represents hydrogen, an alkoxy radical containing 1 to 3 carbon atoms or a group of the formula in which R1 and R2 may independently be selected from the group consisting of methoxy, ethoxy, a lower alkyl or hydroxyalkyl radical containing 1 to 3 carbon atoms, whereby R1 may also represent hydrogen, A is a 2-pyridyl radical, an unsubstituted phenyl radical or a phenyl radical substituted by at least one substituent in the ortho, meta and/or para position, E is selected from the group consisting of hydrogen, methyl, ethyl, propyl, butyl, hydroxyethyl, hydroxypropyl or hydroxybutyl and where the piperidine nucleus is attached at 2-, 3- or 4-position, or pharmaceutically acceptable thereof.