Patent ID: 7459569
Filing Date: 2008-12-02
Classification: A61P,C07D

Abstract:
1. A method of forming an iron hydroxypyrone compound which is a ferric hydroxypyrone complex comprising hydroxypyrone and ferric iron in the stoichiometric ratio of 3:1 hydroxypyrone: ferric iron, which comprises the step of reacting one or more iron salt of a carboxylic acid and one or more hydroxypyrone in an aqueous solution at a pH greater than 7, wherein the aqueous solution comprises one or more base selected from the group consisting of alkali metal hydroxides, sodium or potassium carbonate and mixtures thereof, wherein the carboxylic acid is selected from the group consisting of citric acid, isocitric acid, succinic acid, fumaric acid, maleic acid, malonic acid, aconitic acid, glutaric acid, tartaric acid, gluconic acid, lactic acid, and mixtures thereof, wherein the hydroxypyrone is selected from the group consisting of maltol or ethyl maltol, and mixtures thereof; and wherein the concentration of the base is from 1 to 50% by weight of the aqueous solution.