Patent ID: 8871477
Filing Date: 2014-10-28
Classification: C07K,C12N,C12P

Abstract:
1. A method of producing cadaverine comprising: culturing a transformed microorganism with a gene encoding lysine decarboxylase that extracellularly secretes lysine decarboxylase to increase yield of cadaverine relative to glucose consumption, wherein the microorganism is selected from the group consisting of the microorganism intracellularly expresses a protein comprising lysine decarboxylase having a secretory signal peptide attached to the N-terminus side of the amino acid sequence thereof, which lysine decarboxylase is thereby extracellularly secreted, and the secretory signal peptide is a peptide represented by the amino acid sequence shown in any of SEQ ID NOs: 13 to 43 or a peptide having a sequence identity of not less than 85% to the amino sequence shown in any of SEQ ID NOs: 13 to 43.