Patent ID: 8603396
Filing Date: 2013-12-10
Classification: G01N,Y10T

Abstract:
1. A cell analysis apparatus comprising: a cell source that includes a plurality of cells to be analyzed, each cell defining a cell long axis; a channel that defines a flow axis and through which said cells flow; wherein said cells, when said cell long axis is parallel with said flow axis, have at least a portion that has a flow orthogonal, cell cross-section that is non-circular, wherein said flow orthogonal, cell cross-section has a flow orthogonal, cell cross- section long axis and a flow orthogonal, cell cross-section short axis that is orthogonal to said flow orthogonal, cell cross-section long axis, wherein said channel defines an intended, flow orthogonal, cell cross section long axis alignment line and an intended, flow orthogonal, cell cross section short axis alignment line that is orthogonal to said intended, flow orthogonal, cell cross section long axis alignment line, wherein said channel is configured to orient said cells so that said cell presents at full orientation during a cell illumination, wherein, when said cell is in said full orientation: an EMR projector established to effect said cell illumination by projecting EMR at said cells; a first EMR detector and a second EMR detector, each established to detect EMR emitted as a result of said cell illumination, wherein said first EMR detector has a first detector, flow orthogonal collection angle that defines a flow orthogonal, first detector axis and said second EMR detector has a second detector, flow orthogonal collection angle that defines a flow orthogonal, second detector axis; wherein said flow orthogonal, first detector axis is substantially coaxial with said intended, flow orthogonal, cell cross section long axis alignment line, wherein said flow orthogonal, second detector axis is substantially coaxial with said intended, flow orthogonal, cell cross section short axis alignment line, wherein said flow orthogonal, first detector axis and said flow orthogonal, second detector axis are substantially 90 degrees apart; and a third EMR detector and a fourth EMR detector, each established to detect EMR emitted as a result of said cell illumination, wherein said third EMR detector has a third detector, flow orthogonal collection angle that defines a flow orthogonal, third detector axis and said fourth EMR detector has a fourth dctcctor, flow orthogonal collection angle that defines a flow orthogonal, fourth detector axis, wherein said flow orthogonal, third dctcctor axis and said flow orthogonal, fourth detector axis are substantially 90 degrees apart, and wherein said flow orthogonal, third detector axis is from 30 degrees to 60 degrees from said intended, flow orthogonal, cell cross section long axis alignment line.