Patent ID: 8173679
Filing Date: 2012-05-08
Classification: A61P,C07D

Abstract:
1. A compound of formula (I) or an acid addition salt or a stereoisomeric form thereof, wherein: R R X is O, S, SO, SO R Y is direct bond, O, S, SO, SO R R R n is 1 or 2; A is a (C when X is NR provided that: 1/ when X is NR 4 , where R 4 is H or (C 1 -C 6 )alkyl and R 1 O is 6-OCH 3 , then Y is not CO; 2/ when X is O, R 1 O is 6-OH or 6-OCH 3 , Y is a direct bond and A is cyclopentyl, then (R 2 ,R 3 ) or (R 3 ,R 2 ) is different from (H, Cl) in position 4,5; 3/ when X is O, R 1 O is 6-OH, R 2 is hydrogen, and R 3 is 7-propyl, then Y-A is not a cyclopropyl or a cyclohexylmethyl; 4/ X and Y do not simultaneously represent NH.