Patent ID: 6436152
Filing Date: 2002-08-20
Classification: A61K,A61Q,C07C,C07D

Abstract:
An oxidation dye precursor composition for oxidative dyeing of keratin fibers, said dye precursor composition comprising at least one developer compound and at least one coupler compound;wherein said at least one coupler compound is selected from the group consisting of 2,6-diaminopyridine, 2-amino-4-[(2-hydroxyethyl)amino]anisole, 2,4-diamino-1-fluoro-5-methylbenzene, 2,4-diamino-1-methoxy-5-methylbenzene, 2,4-diamino-1-ethoxy-5-methylbenzene, 2,4-diamino-1-(2-hydroxyethoxy)-5-methylbenzene, 2,4-di[(2-hydroxyethyl)-amino]-1,5-dimethoxybenzene, 2,3-diamino-6-methoxypyridine, 3-amino-6-methoxy-2-(methylamino)pyridine, 2,6-diamino-3,5-dimethoxypyridine, 3,5-diamino-2,6-dimethoxypyridine, 1,3-diaminobenzene, 2,4-diamino-1-(2-hydroxyethoxy)benzene, 2,4-diamino-1,5-di(2-hydroxyethoxy)-benzene, 1-(2-aminoethoxy)-2,4-diaminobenzene, 2-amino-1-(2-hydroxyethoxy)-4-methyl-aminobenzene, 2,4-diaminophenoxyacetic acid, 3-[(di(2-hydroxyethyl)-amino]-aniline, 4-amino-2-di[(2-hydroxyethyl)amino]-1-ethoxybenzene, 5-methyl-2-(1-methylethyl)phenol, 3-[(2-hydroxyethyl)amino]-aniline, 3-[(2-amino-ethyl)-amino]aniline, 1,3-di(2,4-diaminophenoxy)propane, di(2,4-diaminophenoxy)-methane, 1,3-diamino-2,4-dimethoxy-benzene, 2,6-bis(2-hydroxyethyl)amino-toluene, 4-hydroxyindole, 3-dimethylaminophenol, 3-diethylaminophenol, 5-amino-2-methylphenol, 5-amino-4-fluoro-2-methylphenol, 5-amino-4-methoxy-2-methylphenol, 5-amino-4-ethoxy-2-methylphenol, 3-amino-2,4-dicholorophenol, 5-amino-2,4-dichlorophenol, 3-amino-2-methylphenol, 3-amino-2-chloro-6-methylphenol, 3-aminophenol, 2-{(3-hydroxyphenyl)-amino}acetamide, 5-[(2-hydroxyethyl)amino]-2-methylphenol, 3-[(2-hydroxyethyl)-aminophenol, 3-[(2-methoxyethyl)amino]phenol, 5-amino-2-ethylphenol, 2-(4-amino-2-hydroxy-phenoxy)ethanol, 5-[(3-hydroxypropyl)amino]-2-methylphenol, 3-[(2,3-dihydroxy-propyl)amino]-2-methylphenol, 3-[(2-hydroxyethyl)-amino]-2-methylphenol, 2-amino-3-hydroxypyridine, 5-amino-4-chloro-2-methylphenol, 1-naphthol, 1,5-dihydroxynaphthalene, 1,7-dihydroxynaphthalene, 2,3-dihydroxynaphthalene, 2,7-dihydroxynaphthalene, 2-methyl-1-naphthol acetate, 1,3-dihydoxybenzene, 1-chloro-2,4-dihydroxybenzene, 2-chloro-1,3-dihydroxybenzene, 1,2-dichloro-3,5-dihydroxy-4-methylbenzene, 1,5-dichloro-2,4-dihydroxy-benzene, 1,3-dihydroxy-2-methylbenzene, 3,4-methylenedioxyphenol, 3,4-methylenedioxyaniline, 5-[(2-hydroxyethyl)amino]-1,3-benzodioxole, 6-bromo-1-hydroxy-3,4-methylenedioxybenzene, 3,4-diaminobenzoic acid, 3,4-dihydro-6-hydroxy-1,4(2H)-benzoxazine, 6-amino-3,4-dihydro-1,4(2H)-benzoxazine, 3-methyl-1-phenyl-5-pyrazolone, 5,6-dihydroxyindole, 5,6-dihydroxyindoline, 5-hydroxyindole, 6-hydroxyindole, 7-hydroxyindole and 2,3-indolindione; and wherein said at least one developer compound includes at least one substituted 2-aminoalkyl-1,4-diaminobenzene compound of the formula (I): whereinR1, R2, R3 and R4, independently of each other, are each hydrogen, a C1- to C6-alkyl group, a C1- to C4-hydroxyalkyl group, a C2- to C4-dihydroxyalkyl group or a C1- to C4-alkoxy-(C1- to C2-)alkyl group, or R1 and R2 together with N form a four member to eight member aliphatic ring; wherein at least two of said R1, R2, R3 and R4 represent hydrogen and wherein R3 and R4 are not both simultaneously a C1- to C6-alkyl group; R5 represents hydrogen, a halogen atom, a C1- to C4-alkyl group, a C1- to C4-hydroxyalkyl group or a C1- to C4-alkoxy group; R6 and R7, independently of each other, each represent hydrogen, a C1- to C2-alkoxy group, a C1- to C6-alkyl group, a C1- to C6-alkenyl group, a C1- to C4-hydroxyalkyl group, a C3- to C4-dihydroxyalkyl group, a C1- to C4-aminoalkyl group, a C1- to C4-dimethylaminoalkyl group, a C1- to C4-acetylaminoalkyl group, a C1- to C4-methoxyalkyl group, a C1- to C4-ethoxyalkyl group, a C1- to C4-cyanoalkyl group, a C1- to C4-carboxyalkyl group, a C1- to C4-aminocarbonylalkyl group, a pyridylmethyl group, a furfuryl group, a hydrogenated furfuryl group, a substituted pyridyl group, a group of the formula II: a group of the formula III: a group of the formula IV: wherein at least one of R6 and R7 is not hydrogen or R6 and R7 together with N form one of the following rings: R8 represents hydrogen or a C1- to C6-alkyl group; R9 represents hydrogen, a carboxy group or an aminocarbonyl group; R10 and R11, independently of each other, each represent hydrogen, a hydroxy group, an aminocarbonyl group, a methylthiomethyl group, a substituted phenyl group having a phenyl group substituent or a hydroxy group substitutent or a group of the formula: whereinR12, R13, R14, R15 and R16 are each, independently of each other, hydrogen, a halogen atom, a cyano group, a hydroxy group, a C1- to C4-alkoxy group, a C1- to C4-hydroxyalkoxy group, a C1- to C6-alkyl group, a C1- to C4-alkylthioether group, a mercapto group, a nitro group, an amino group, an alkylamino group, a hydroxyalkylamino group, a dialkylamino group, a di(hydroxyalkyl)amino group, a (dihydroxyalkyl)amino group, a (hydroxyalkyl)-alkylamino group, a trifluoromethane group, a â€”C(O)H group, a â€”C(O)CH3 group, a â€”C(O)CF3 group, a â€”Si(CH3)3 group, a C1- to C4-hydroxyalkyl group, a C3- to C4-dihydoxyalkyl group, or two of the groups R12 to R16 next to each other form an â€”Oâ€”CH2â€”Oâ€” bridge; R17 represents a C1- to C4-alkyl group or a C1- to C4-hydroxyalkyl group; R18 represents hydrogen or a C1- to C6-alkyl group; R19 represents one or more hydrogen, hydroxy, carboxy, aminocarbonyl or hydroxymethyl group or groups; and R20 represents hydrogen or a C1- to C6-alkyl group, with the proviso that R1, R2 and R8 are not each hydrogen when (i) R5 is in the 5-position of the aromatic ring and R5 is hydrogen, a C1- to C4-alkyl group or a halogen atom, and when (ii) R6 and R7, independently of each other, are a C1- to C4-alkyl group or a phenyl group; or a physiologically compatible, water-soluble salt of said at least one substituted 2-aminoalkyl-1,4-diaminobenzene compound of the formula (I).