Patent ID: 6768007
Filing Date: 2004-07-27
Classification: C07D,C07F

Abstract:
A compound of Formula I: or a pharmaceutically acceptable salt, ester, or prodrug thereof; whereinR1 and R4 are independently selected from the group consisting of hydrogen, halogen, hydroxy, alkyl, alkoxy, acyloxy, amino, monoalkylamino, dialkylamino, trifluoromethyl, trifluoromethoxy, â€”CH2CONH-alkyl, and C1-4 alkyl substituted with one or more of halogen, trifluoromethyl, cyano, hydroxy, amino, monoalkylamino, or dialkylamino, wherein at least one of R1 or R4 is the substituted C1-4 alkyl group; R2 and R3 are independently selected from the group consisting of hydrogen, halogen, hydroxy, alkyl, alkoxy, acyloxy, amino, monoalkylamino, dialkylamino, trifluoromethyl, trifluoromethoxy, phenyl, and â€”CH2CONH-alkyl; X and Z are independently selected from the group consisting of O, S and NH; and where the configurations at 3â€² and 4â€² can be (R) or (S).