Patent ID: 6437126
Filing Date: 2002-08-20
Classification: A01N,C07D

Abstract:
A process for preparing a substituted phenyluracil of the formula whereinR1 represents a moiety selected from the group consisting of hydrogen; fluorine; chlorine; bromine; unsubstituted C1 to C4-alkyl; and, fluorine or chlorine-substituted C1-C4-alkyl; R2 represents unsubstituted C1-C4-alkyl or fluorine- and/or chlorine-substituted C1-C4-alkyl; R3 represents a moiety selected from the group consisting of hydrogen; amino; unsubstituted C1-C6-alkyl; cyano-, fluorine-, chlorine- or C1-C4-alkoxy-substituted C1-C6-alkyl; unsubstituted C2-C6-alkenyl or C2-C6-alkynyl; and, fluorine- and/or chlorine-substituted C2-C6-alkenyl or C2-C6-alkynyl; R4 represents hydrogen, cyano, fluorine or chlorine, R5 represents cyano or thiocarbamoyl, and R6 represents one of the following groups: â€ƒwherein Q1 and Q2 each represent oxygen or sulphur, R7 represents a moiety selected from the group consisting of hydrogen; unsubstituted C1-C4-alkyl; and halogen- or C1-C4-alkoxy-substituted C1-C4-alkyl; R8 represents a moiety selected from the group consisting of hydrogen; hydroxyl; amino; unsubstituted C1-C6-alkyl, C1-C6-alkoxy, C1-C6-alkylamino, di-(C1-C4-alkyl)-amino, C1C4-alkylcarbonylamino or C1-C4-alkyl-sulphonylamino; C1-C6-alkyl, C1-C6-alkoxy, C1-C6-alkylamino, di-(C1-C4-alkyl)-amino, C1-C4-alkylcarbonylamino or C1-C4-alkyl-sulphonylamino, each of which is substituted by halogen, C1-C4-alkoxy or C1-C4-alkoxy-carbonyl; unsubstituted C2-C6-alkenyl, C2-C6-alkenyloxy or C2-C6-alkinyl; C2-C6-alkenyl, C2-C6-alkenyloxy or C2-C6-alkinyl, each of which is substituted by halogen; C3-C6-cycloalkyl, C3-C6-cyclo-alkyloxy, C3-C6-cycloalkylamino, C3-C6-cycloalkyl-carbonyl-amino or C3-C6-cycloalkylsulphonylamino, each of which may be substituted by halogen or C1-C4-alkyl; and, phenyl, phenoxy, phenylamino, phenylcarbonylamino, phenylsulphonylamino, phenyl-C1-C4-alkyl, phenyl-C1-C4-alkoxy, phenyl-C1-C4-alkylamino, each of which may be substituted by halogen, C1-C4-alkyl, C1-C4-halogenoalkyl, C1-C4-alkoxy or C1-C4-halogenoalkoxy; and R9 and R10 each represent C1-C4-alkyl comprising: (a) reacting a carbonyl phenyluracil of the formula (Ia) â€ƒwherein R1, R2, R3, R4, R5 and R7 are each as defined above with an amino compound of the general formula (III) H2Nâ€”R8â€ƒâ€ƒ(III) whereinâ€ƒR8 is as defined above or with acid adducts of compounds of the formula (III); or (b) reacting a carbonylphenyluracil of the formula (Ia) â€ƒwherein R1, R2, R3, R4, R5 and R7 are each as defined above with an alcohol and/or a mercaptan of the formula (IVa) or (IVb) â€ƒwherein Q1,Q2, R9 and R10 are each as defined above.