Patent ID: 9175048
Filing Date: 2015-11-03
Classification: A61K,C07K,C12N

Abstract:
1. A composition, comprising: a target polypeptide selected from the group consisting of a mouse eukaryotic initiation factor 3 (eIF3-f) comprising SEQ ID NO: 19, human eIF3-f comprising SEQ ID NO: 20, and a protein having a 4.1 ezrin, radixin, moesin (FERM) domain comprising SEQ ID NO: 27; and a transporter polypeptide comprising the DNA-binding domain (DB) and the leucine zipper type dimerization domain (DIM) of an EBV ZEBRA protein comprising the amino acid sequence of SEQ ID NO: 1, wherein the target polypeptide is linked to the transporter polypeptide by a covalent bond, a non-covalent bond, an ionic bond, a hydrogen bond, or a hydrophobic bond.