Patent ID: 9017669
Filing Date: 2015-04-28
Classification: A61K,A61P,C07K,G01N

Abstract:
1. An antibody or an antigen binding fragment thereof, wherein the antibody comprises an H (heavy) chain V (variable) region and an L (light) chain V region, wherein the H chain V region and the L chain V region selected from the group consisting of: (a) an H chain V region comprising complementarity determining regions (CDRs) included in an H chain V region having the amino acid sequence shown in SEQ ID NO: 4, and an L chain V region comprising CDRs included in an L chain V region having the amino acid sequence shown in SEQ ID NO 12; (b) an H chain V region comprising CDRs included in an H chain V region having the amino acid sequence shown in SEQ ID NO: 20, and an L chain V region comprising CDRs included in an L chain V region having the amino acid sequence shown in SEQ ID NO: 28; and (c) an H chain V region comprising CDRs included in an H chain V region having the amino acid sequence shown in SEQ ID NOs: 68, 72, 76 or 80, and an L chain V region comprising CDRs included in an L chain V region having the amino acid sequence shown in SEQ ID NO: 60, and wherein the antibody is capable of binding to a CDH3 polypeptide or a partial peptide thereof.