Patent ID: 6777441
Filing Date: 2004-08-17
Classification: A61P,C07C,C07D

Abstract:
A compound of the formula (V): or its pharmaceutically acceptable salt thereof, wherein: (a) B, D and E are independently O; (b) G is OR11, NR11R12 or SR11; (c) R1, R2, R3, R4, R5 and R6 are independently hydrogen, alkyl, alkenyl, alkynyl, aryl, alkaryl, arylalkyl; a moiety selected from optionally substituted furyl, furanyl, pyridyl, pyrimidyl, thienyl, isothiazolyl, imidazolyl, tetrazolyl, pyrazinyl, benzofuranyl, benzothiophenyl, quinolyl, isoquinolyl, benzothienyl, isobenzofuryl, pyrazolyl, indolyl, isoindolyl, benzimidazolyl, purinyl, carbazolyl, oxazolyl, thiazolyl, isothiazolyl, 1,2,4-thiadiazolyl, isooxazolyl, pyrrolyl, quinazolinyl, cinnolinyl, phthalazinyl, xanthinyl, hypoxanthinyl, thiophene, furan, pyrrole, isopyrrole, pyrazole, and imidazole; and (d) each R7, R8, R9, R10, R11 and R12 is independently hydrogen, alkyl, alkenyl, alkynyl, aryl, alkaryl, arylalkyl; a moiety selected from optionally substituted furyl furanyl, pyridyl, pyrimidyl, thienyl, isothiazolyl, imidazolyl, tetrazolyl, pyrazinyl, benzofuranyl, benzothiophenyl, quinolyl, isoquinolyl, benzothienyl, isobenzofuryl, pyrazolyl, indolyl, isoindolyl, benzimidazolyl, purinyl, carbazolyl, oxazolyl, thiazolyl, isothiazolyl, 1,2,4-thiadiazolyl, isooxazolyl, pyrrolyl, quinazolinyl, cinnolinyl, phthalazinyl, xanthinyl, hypoxanthinyl, thiophene, furan, pyrrole, isopyrrole, pyrazole, and imidazole.