Patent ID: 8993236
Filing Date: 2015-03-31
Classification: C12Q,G01N,Y10T

Abstract:
1. A detection device comprising: an electromagnetic detector; a first binding moiety comprising a first binding site; a second binding moiety comprising a second binding site; and an electromagnetic material; wherein the first binding moiety is attached to the electromagnetic detector prior to binding of an analyte to the first binding moiety, wherein the second binding moiety is attached to the electromagnetic material prior to the binding of the analyte to the second binding moiety, wherein the device is configured such that binding of the analyte to the first binding site and the second binding site changes the relationship between the electromagnetic detector and the electromagnetic material such that the change in the relationship is detected by the electromagnetic detector as a change in electromagnetic field, wherein the analyte is a nucleic acid, and wherein at least one of the first binding moiety and the second moiety is a nucleic acid and internally hybridizes in the absence of the analyte.