Patent ID: 7319013
Filing Date: 2008-01-15
Classification: C12N

Abstract:
1. A method for identifying herbicidally active substances comprising a) bringing a polypeptide with the enzymatic activity of a serine hydroxymethyltransferase into contact with one or more test compounds under conditions which permit the test compound(s) to bind to the polypeptide; and b) detecting whether the test compound inhibits the activity of the polypeptide of a), wherein inhibition is an indication that the test compound is herbicidally active, wherein said polypeptide is encoded by a nucleic acid sequence selected from the group consisting of: a) the nucleic acid sequence shown in SEQ ID NO:7; b) a nucleic acid sequence encoding the amino acid sequence shown in SEQ ID NO:8; and c) a nucleic acid sequence encoding serine hydroxymethyltransferase having at least 95% identity to SEQ ID NO:7.