Patent ID: 6121322
Filing Date: 2000-09-19
Classification: A61P,C07C,C07D,C07F

Abstract:
Compounds of the formula ##STR7## wherein R.sub.100 and R.sub.300 each independently signify hydrogen or C.sub.1 -C.sub.6 -alkoxycarbonyl,R.sub.200 signifies hydrogen, amino, C.sub.1 -C.sub.6 -alkylcarbonylamino or di-C.sub.1 -C.sub.6 -alkylcarbonylamino,R.sub.400 signifies R.sub.800 XON(R.sub.7)COCH.sub.2 --,R.sub.500 and R.sub.600 each independently signify hydrogen or C.sub.1 -C.sub.6 -alkoxy,R.sub.7 signifies hydrogen or C.sub.1 -C.sub.6 -alkyl,X signifies a valency bond, C.sub.1 -C.sub.6 -alkylene, carbonyl or C.sub.1 -C.sub.6 -carbonylalkylene,R.sub.800 signifies C.sub.1 -C.sub.6, which may be substituted by one or more same or different substituents selected from hydroxy, amino, C.sub.1 -C.sub.6 -alkylamino and di-C.sub.1 -C.sub.6 -alkylamino, 2,2-di-C.sub.1 -C.sub.6 -alkyl-1,3-dioxolan-4-yl or PO(OR.sub.13)(OR.sub.4), and, when X signifies other than a valency bond, R.sub.800 also signifies hydroxy, C.sub.1 -C.sub.6 -alkoxy, hydroxy-C.sub.1 -C.sub.6 -alkyl or NR.sub.900 R.sub.1000,R.sub.900 and R.sub.1000 each individually signify hydrogen, C.sub.1 -C.sub.6 -alkyl, which may carry one or more same or different substituents selected from hydroxy, C.sub.1 -C.sub.6 -alkoxy and amino andR.sub.13 and R.sub.14 each individually signify hydrogen or C.sub.1 -C.sub.6 -alkyl,as well as their tautomers, enantiomers, diastereomers, racemates and physiologically compatible salts or esters.