Patent ID: 7202392
Filing Date: 2007-04-10
Classification: A01K,C12N,G01N

Abstract:
1. A method of evaluating the effect of a plurality of test compounds on the signals produced by a reporter molecule of a tissue of a transgenic non-human animal, the method comprising: providing a transgenic non-human animal whose genome comprises a transgene comprising a nucleic acid which encodes a reporter molecule functionally linked to the control region of a gene, the reporter molecule being the source of signals; contacting a tissue from the transgenic animal with the plurality of test compounds to thereby form on the tissue an array of a plurality of individually addressable regions or addresses, each region or address of the plurality including a test compound which differs from those at other addresses of the plurality; and evaluating the signals produced by the reporter molecule at each of the plurality of regions or addresses thereby evaluating the effect of a plurality of test compounds on the signals produced by the reporter molecule in the tissue of the non-human transgenic animal.