Patent ID: 8445466
Filing Date: 2013-05-21
Classification: A61K,A61P

Abstract:
1. An aqueous composition for administering, to a mammal, an amide-protected, biologically active form of creatine that is stable in an aqueous system, wherein said composition comprises: a) at least one creatyl-amide species, and b) water; wherein, in said creatyl-amide species, the carboxylic acid group of creatine is linked, via an amide bond, to an amino group of a species selected from the group consisting of glutamine, leucine, arginine, histidine, isoleucine, lysine, methionine, threonine, tryptophan, tyrosine, valine, alanine, asparagine, aspartate, cysteine, glutamate, glycine, proline, serine, carnosine, 1-methylhistidine, beta-alanyl-1-methylhistidine sarcosine, β-alanine, citrulline, ornithine, prolinamide, 5-hydroxylysine, alanyl-L-glutamine, taurine, and geranamine.