Patent ID: 8907095
Filing Date: 2014-12-09
Classification: A61K,A61P,C07D

Abstract:
1. A compound having the formula: or a pharmaceutically acceptable salt thereof, wherein: W is a bond, —C(O)—O—or —S(O) X is —O—or —NH—; Y is —O—, such that the group —Y-A-X—B—can be in an exo- or endo- configuration with respect to the bicyclic ring to which variable Y is attached; Z is a bond, —CH A is  wherein Q is H, alkyl, halo or —O-alkyl B is aryl or a -5- or 6-membered heteroaryl group, each of which can be unsubstituted or optionally substituted with up to 3 groups, which can be the same or different, and are selected from: alkyl, heteroaryl, halo, —CN, —S(O) R p is 0, 1 or 2; q is 0, 1 or 2; r is 0, 1 or 2; s is 0, 1 or 2; and u is 0, 1 or 2.