Patent ID: 8302781
Filing Date: 2012-11-06
Classification: B01D

Abstract:
1. A semipermeable hollow-fibre membrane, particularly for use in hemodialysis, hemodiafiltration and hemofiltration, comprising a hydrophilic, water-wettable membrane being based on possessing an open-pored, integrally asymmetric structure across its wall with a porous separating layer of thickness 0.1 to 2 μm on its inner surface facing a lumen and an open-pored supporting layer adjoining the separating layer, characterized in that a polyelectrolyte with negative fixed charges is physically bound in the separating layer, characterized in that the supporting layer being essentially free from polyelectrolyte with negative fixed charges, and having an ultrafiltration rate in albumin solution in the range of 25 to 60 ml/(h·m wherein after drying, the hollow-fibre membrane has a minimum sieving coefficient for cytochrome c of 0.8 combined with a maximum sieving coefficient for albumin of 0.005, and whereby the hollow-fibre membrane in the dry state is free from pore-stabilising additives in the membrane wall.