Patent ID: 8389571
Filing Date: 2013-03-05
Classification: A61P,C07D

Abstract:
1. A method of treating a patient suffering from HIV infection, comprising administering to said patient a compound of formula (II): or a pharmaceutically acceptable salt thereof; wherein OE is a phosphate, phosphonate, or carboxylate ester and wherein said compound is hydrolyzed in vivo to a compound of formula (II) where E is H; R is C or R is —(CR1R1) R2 is C X′ is absent or is —O—, —S—, —NH—, —NHC(O)—, —NHC(O)O—, —NHSO Y′ is C wherein each R3 independently is selected from the group consisting of H, aryl, heteroaryl, C each R4 independently is selected from H, or C each R5 independently is selected from the group consisting of H, C wherein R6 and R6′ independently are selected from the group consisting of H, C