Patent ID: 7807682
Filing Date: 2010-10-05
Classification: A61K,A61P,C07D

Abstract:
1. A method for treating small cell lung carcinoma comprising administering to a patient in need thereof an effective amount of a compound of formula I wherein R1 represents hydrogen, halogen, methyl or one or more straight or branched, saturated or unsaturated C 2-6 hydrocarbon radical, optionally substituted with halogen, hydroxy, cyano, nitro, carboxy, alkoxy, alkoxycarbonyl, alkylcarbonyl, formyl, amino, aminoalkyl, aminocarbonyl, alkylcarbonylamino, sulfo, aminosulfonyl, alkylsulfonylamino, hydroxysulfonyloxy, dihydroxyphosphinoyloxy or phosphono; X represents a straight or branched, saturated or unsaturated C Y represents a bond, O, C(O), S, S(O), S(O) Z represents an aromatic heterocyclic radical with 5-12 ring atoms, optionally substituted with halogen, methyl, hydroxy, cyano, nitro, alkoxy, alkoxycarbonyl, alkylcarbonyl, formyl, aminoalkyl or a straight or branched, saturated or unsaturated C provided that R1 is not attached to the nitrogen-atom in the pyridyl ring; or pharmaceutically acceptable salts, hydrates, N-oxides or prodrugs thereof.