Patent ID: 8183295
Filing Date: 2012-05-22
Classification: A61K,A61P

Abstract:
1. A pharmaceutical composition consisting of (i) 150-500 mg aliskiren or a pharmaceutically acceptable salt thereof, (ii) 1.0-40 mg amlodipine or a pharmaceutically acceptable salt thereof, (iii) 5-200 mg hydrochlorothiazide, and one or more pharmaceutically acceptable carriers, wherein the amounts of (i) aliskiren or a pharmaceutically acceptable salt thereof, (ii) amlodipine or a pharmaceutically acceptable salt thereof and (iii) hydrochlorothiazide administered in combination achieve a greater therapeutic effect than the therapeutic effects achievable with the amounts of (i) aliskiren or a pharmaceutically acceptable salt thereof, (ii) amlodipine or a pharmaceutically acceptable salt thereof and (iii) hydrochlorothiazide administered alone.