Patent ID: 6777246
Filing Date: 2004-08-17
Classification: G01N,Y10S

Abstract:
A reagent for use in immunoassays, comprising:a plurality of particles, each of said particles comprising a surface having been activated by a carbodiimide; a binding agent selected from the group consisting of antigens and antibodies linked to the carbodiimide through a covalent bond; and a tertiary amine compound of the formula N(R1â€”X)(R2â€”Y)(R3â€”Z) wherein R1, R2, and R3 are independently selected from the group consisting of alkyl and alkyl ether; and X, Y, and Z are independently selected from the group consisting of â€”OH, â€”Oâ€”R4, â€”Sâ€”R4, â€”C(&boxH;O)â€”OH, â€”C(&boxH;O)â€”OR4, and â€”C(&boxH;O)-NHR4, wherein R4 is alkyl.