Patent ID: 7144892
Filing Date: 2006-12-05
Classification: A61K,A61P

Abstract:
1. A method of treating myocardial infarction in a mammal comprising: concurrently administering to the mammal a therapeutically effective amount for treating myocardial infarction of a combination of a compound selected from the group consisting of pyridoxal-5′-phosphate, pyridoxine, pyridoxal, pyridoxamine, a 3-acylated pyridoxal analogue, a pharmaceutically acceptable acid addition salt thereof, and a mixture thereof, and a therapeutic cardiovascular compound selected from the group consisting of an angiotensin converting enzyme inhibitor, an angiotensin II receptor antagonist, a calcium channel blocker, an anti-thrombotic agent, a β-adrenergic receptor antagonist, a vasodilator, a diuretic, α-adrenergic receptor antagonist, an antioxidant, and a mixture thereof, wherein the 3-acylated pyridoxal analogue is a compound of the formula wherein R R