Patent ID: 6875568
Filing Date: 2005-04-05
Classification: C12N,C12Q

Abstract:
1. A method for hybridizing one or more nucleic acid molecules, said method comprising i) contacting one or more double-stranded nucleic acid molecules with a denaturant selected from the group consisting of thereby forming one or more single-stranded target nucleic acid molecules; and ii) combining said one or more single-stranded target nucleic acid molecules with one or more additional nucleic acid molecules wherein said one or more additional nucleic acid molecules are capable of hybridizing to said single-stranded target nucleic acid molecules thereby obtaining one or more of said hybridized nucleic acid molecules; wherein said amino acid denaturants are selected from the ground consisting of one or more amino acids, polyamino acids, and combinations thereof; wherein said amino acid denaturants denature or separate double-stranded nucleic acid molecules.