Patent ID: 6627452
Filing Date: 2003-09-30
Classification: G01N

Abstract:
A method of selecting a drug for a patient suffering from a disease selected from the group consisting of cancer, viral diseases and autoimmune diseases comprisingobtaining samples of heparinized whole blood from the patient; determining the amount of sulfhydryl and disulfide groups in one of the samples of heparinized whole blood; calculating the ratio of sulfyhdryl groups to disulfide groups for that sample of heparinized whole blood; adding to a series of the remaining samples of heparinized whole blood drugs appropriate for the treatment of the disease at a dose in a ratio of to 1:5000 of the therapeutic dose of each drug; incubating each drug in each sample of heparinized whole blood; determining the amount of sulfhydryl and disulfide groups in each sample of heparinized whole blood to which a drug has been added; calculating the ratio of sulfyhdryl groups to disulfide groups for each sample of heparinized whole blood to which a drug has been added; selecting the drug to be administered to the patient that produced the greatest increase in the ratio of sulfhydryl groups to disulfide groups in a sample of heparinized whole blood from the patient.