Patent ID: 8431135
Filing Date: 2013-04-30
Classification: A61K,A61P,C07K,G01N

Abstract:
1. A vaccine against a Borrelia infection comprising a protein, said protein comprising a first OspC polypeptide comprising one or more cysteines and a second OspC polypeptide comprising one or more cysteines, wherein the first OspC polypeptide is linked to the second OspC polypeptide via a disulphide bridge formed between the most N-terminal cysteines in the first and second OspC polypeptides, and wherein both the first and second OspC polypeptides comprise at least one epitope that is specifically recognized by antibodies against OspC from Borrelia , the epitope comprising at least 10 contiguous amino acids from SEQ ID NO:3, SEQ ID NO:6, or SEQ ID NO:9.