Patent ID: 8354412
Filing Date: 2013-01-15
Classification: A61P,C07C,C07D

Abstract:
1. A compound selected from (S)-1-phenoxy-2-hydroxy-3-[4-(4-methoxybenzenesulfonyl)piperazin-1-yl]propane (2a); (S)-1-(4-hydroxyphenoxy)-2-hydroxy-3-[4-(4-methoxybenzenesulfonyl)piperazin-1-yl]propane (2b); (S)-1-(4-benzyloxyphenoxy)-2-hydroxy-3-[4-(4-methoxybenzenesulfonyl)piperazin-1-yl]propane (2c); (S)-1-(3-nitrophenoxy)-2-hydroxy-3-[4-(4-methoxybenzenesulfonyl)piperazin-1-yl]propane (2d); (S)-1-(3-aminophenoxy)-2-hydroxy-3-[4-(4-methoxybenzenesulfonyl)piperazin-1-yl]propane (2e); (S)-2-hydroxy-1-(3-metanesulfonylaminophenoxy)-3-[4-(4-methoxyphenylsulfonyl)piperazin-1-yl]propane (2f); (S)-1-(3-benzenesulfonylaminophenoxy)-2-hydroxy-3-[4-(4-methoxyphenylsulfonyl)piperazin-1-yl]propane (2g); (S)-2-hydroxy-3-[4-(4-methoxyphenylsulfonyl)piperazin-1-yl]-1-(3-thiophenesulfonylaminophenoxy)propane (2h); (S)-2-hydroxy-3-[4-(4-methoxyphenylsulfonyl)piperazin-1-yl]-1-(napht-1-yloxy)propane (2i); (S)-1-(carbazol-4-yloxy)-2-hydroxy-3-[4-(4-methoxybenzenesulfonyl)piperazin-1-yl]propane (2j); and its salts and solvates.