Patent ID: 6531464
Filing Date: 2003-03-11
Classification: A61P,C07D

Abstract:
A method for treating a symptom associated with multiple sclerosis in a subject, the method comprising administering to said subject a compound of Formula I: or a pharmaceutically acceptable base or acid addition salt, hydrate, ester, solvate, or a mixture thereof, wherein:X is C&boxH;O; Q is NHCO; R1, R3, R4, R5, R7, R8, R9, R10, are, independently, hydrogen or lower alkyl; Y1 and Y2 are hydrogen; n is 0 to 10; and Z1 and Z2 are, independently: hydrogen, alkylhalo, alkylhydroxy, C1-C10 straight or branched chain alkyl, C2-C10 straight or branched chain alkenyl group, C2-C10 straight or branched chain alkynyl group, aryl, benzyl, alkylamino, alkylcarboxy, alkylester, arylalkyl, or Z1 or Z2 taken together form a fused ring, wherein said ring has 4-8 ring members; the compound being in an amount effective for treating a symptom associated with multiple sclerosis in said subject.