Patent ID: 9062278
Filing Date: 2015-06-23
Classification: A61K,A61Q,C07C,C11D

Abstract:
1. A process for preparing an ether carboxylate of formula I from a corresponding alkoxylate of formula II, wherein R1 is a C X is O, COO, CH N(CH 2 ) t O for q=2 and r=0 to 20, r is an integer from 0 to 50, R2 is H or C R3 is H or C R4 is H or C M is H or a metal, ammonium, or an organic base, n is from 0 to 50, m is from 0 to 40, p is from 0 to 40, q is from 1 to 2, s is 0 or 1, t is from 0 to 20, provided that n+m+p is at least 1 and R is C the process comprising: charging a reaction vessel with the alkoxylate of formula II and a transition metal catalyst to obtain a reaction mixture in the vessel; adjusting the temperature of the reaction mixture to a reaction temperature of from 140 to 220° C.; maintaining a pressure of less than 10 bar in the reaction vessel during reaction; adding a base to the reaction mixture at reaction temperature and pressure, and removing water from the reaction mixture during reaction to obtain the ether carboxylate of formula I.