Patent ID: 6191301
Filing Date: 2001-02-20
Classification: A61K,A61P,A61Q,C07C

Abstract:
A 4,4-diarylbutadiene of the formula I, ##STR17##where the diene system has the Z,Z; Z,E; E,Z or E,E configuration or a mixture thereof, and where the variables independently of one another have the following meanings:R.sup.1 and R.sup.2hydrogen, C.sub.1 -C.sub.20 -alkyl, C.sub.2 -C.sub.10 -alkenyl, C.sub.3 -C.sub.10 -cycloalkyl, C.sub.3 -C.sub.10 -cycloalkenyl, C.sub.1 -C.sub.12 -alkoxy, C.sub.1 -C.sub.20 -alkoxycarbonyl, C.sub.1 -C.sub.12 -alkylamino, C.sub.1 -C.sub.12 -dialkylamino, aryl, hetaryl, unsubstituted or substituted substituents, which confer solubility in water, and are selected from the group consisting of carboxylate, sulfonate or ammonium radicals;R.sup.3 hydrogen, COOR.sup.5, COR.sup.5, CONR.sup.5 R.sup.6, CN;R.sup.4 COOR.sup.6, COR.sup.6, CONR.sup.5 R.sup.6 ;R.sup.5 hydrogen, [X].sub.o -R.sup.7, C.sub.1 -C.sub.6 -alkylene-SO.sub.3 Y, C.sub.1 -C.sub.6 -alkylene-PO.sub.3 Y, C.sub.1 -C.sub.6 -alkylene-N(R.sup.8).sub.3.sup.+ A.sup.- ;R.sup.6 [X].sub.o -R.sup.7, C.sub.1 -C.sub.6 -alkylene-SO.sub.3 Y, C.sub.1 -C.sub.6 -alkylene-PO.sub.3 Y, C.sub.1 -C.sub.6 -alkylene-N(R.sup.8).sub.3.sup.+ A.sup.- ;X --CH.sub.2 --CH.sub.2 -Z-, --CH.sub.2 --CH.sub.2 --CH.sub.2 -Z-, --CH (CH.sub.3) --CH.sub.2 -Z-, --CH.sub.2 --CH.sub.2 --CH.sub.2 --CH.sub.2 -Z-, --CH.sub.2 --CH(CH.sub.2 --CH.sub.3)-Z-;A Cl, Br, I, SO.sub.4 R.sup.9 ;Y hydrogen, Na.sup.+, K.sup.+, Mg.sup.2+, Ca.sup.2+, Li.sup.+, Al.sup.3+, N(R.sup.8).sub.4.sup.+ ;Z O, NH;R.sup.7 and R.sup.8hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.2 -C.sub.6 -alkenyl, C.sub.1 -C.sub.6 -acyl;R.sup.9 hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.2 -C.sub.6 -alkenyl;n 1 to 3;o 1 to 150.