Patent ID: 9005995
Filing Date: 2015-04-14
Classification: A61B,A61K,A61M,A61P,G01R,Y10S,Y10T

Abstract:
1. A method for targeting a three-dimensional particle or biocapsule to a cell within a subject, wherein the three-dimensional particle or biocapsule comprises a plurality of two-dimensional faces capable of self-folding to form a hollow interior, wherein a size of the particle or biocapsule is microscale or nanoscale, and wherein the plurality of two-dimensional faces comprise a folding hinge between two adjacent faces and a locking or sealing hinge on an edge of a two-dimensional face, wherein the folding hinge between two adjacent faces has a width that is about twice a width of the locking or sealing hinge on an edge, wherein the plurality of two-dimensional faces comprising the three-dimensional particle or biocapsule are permanently held together by solid hinges; the method comprising: i) attaching to the particle or biocapsule an antibody against an antigen specific to the cell; and ii) introducing the particle or biocapsule into the subject, wherein the particle or biocapsule is targeted to the cell.