Patent ID: 6573388
Filing Date: 2003-06-03
Classification: C07C,C07D,C07F,Y02P

Abstract:
An ethylaziridine derivative of the formula (Iâ€²) wherein,R3 is selected from the group consisting of H, alkyl, aryl, arylakyl, an amino protecting group forming a C5-7 monocyclic heterocycle with the N atom, and an amino protecting group forming a C7-11 bicyclic heterocycle with the N atom; R4 is a silyl proticting group optionally substituted with alkyl or an alcohol protecting group selected from the group consisting of alkoxycarbonyl, aryloxycarbonyl, methoxymethyl, tetrahydropyranyl, methoxyethoxy methyl or ethoxyvinylethyl; Z is F, CI, Br, I, or â€”OSOnR5, where n=0, 1, or 2, and R5 is alkyl or aryl.