Patent ID: 7138416
Filing Date: 2006-11-21
Classification: A61P,C07D

Abstract:
1. A compound represented by general formula (I), or a stereoisomer thereof wherein X is O, S, SO, SO n is 1; k is 1; Z is O, S, and NR7; R1 at two positions are independently selected from hydrogen or a substituted or unsubstituted group selected from linear or branched (C R2, R3, R4 and R7 are independently selected from hydrogen, perhaloalkyl, (CO)NR8R9, —(CO)R8, —(CO)OR8, —SO R5 and R6 are independently selected from by hydrogen or a substituted or unsubstituted group selected from linear or branched (C R8 and R9 are independently selected from hydrogen or a substituted and unsubstituted group selected from linear or branched (C wherein in the groups represented by R1, R2, R3, R4, R5, R6, R7, R8 and R9 when substituted, the substitutents are optionally and independently bridged by —(CO)—, —(CO)O, —(CO)NH—, —NH—, —NR8-, —O—, —S—, —(SO)—, —(SO and wherein R10 is independently selected from halogen, hydroxy, nitro, cyano, amino, oxo or oxime; or a pharmaceutically acceptable hydrate or salt thereof.