Patent ID: 6884628
Filing Date: 2005-04-26
Classification: A61B,A61L,B82Y,G01N,Y10S

Abstract:
1. A method for reducing non-specific adsorption of inorganic ions, peptides, proteins, and saccharides to a surface of a device comprising applying to or coating onto a surface of an analytical or sensing device, wherein the surface comprises a material selected from the group consisting of metals, metal oxides, and charged polymers. a non-interactive polyionic multifunctional copolymer, wherein the non-interactive polyionic multifunctional copolymer comprises non-interactive polymer sidechains covalently grafted onto a charged polyionic polymeric backbone which has an anionic charge at a pH greater than 4, wherein the polyionic polymeric backbone interacts with the surface at a pH greater than 4, where some or all of the non-interactive polymer sidechains are partially or fully functionalized at or near the free terminal position of the non-interactive polymer sidechains with a functional molecule.