Patent ID: 6447786
Filing Date: 2002-09-10
Classification: A61K,C07K

Abstract:
A purified peptide characterized as:(i) inhibiting or activating agr-rnaIII transcription in S. aureus; and (ii) consisting of about six to about twelve amino acids in length; wherein the about six to about twelve amino acids comprise a sequence with a cysteine residue from an AgrD region of a staphylococci bacterium, the sequence selected from the group consisting of: (a) Asp-Ile-Cys-Asn-Ala-Tyr-Phe (SEQ ID NO:1); (b) Tyr-Ser-Thr-Cys-Asp-Phe-Ile-Met (SEQ ID NO:2); (c) Gly-Val-Asn-Ala-Cys-Ser-Ser-Leu-Phe (SEQ ID NO:3); and (d) Tyr-Ile-Asn-Cys-Asp-Phe-Leu-Leu (SEQ ID NO:4).