Patent ID: 6201065
Filing Date: 2001-03-13
Classification: A61K,A61L,C08G,C08L,Y10S

Abstract:
A macromer which is capable of forming a gel, the macromer comprising a total of five or ten covalently linked polymeric blocks, wherein:a) at least one polymer block is hydrophilic and each hydrophilic polymer block individually has a water solubility of at least 1 gram/liter;b) at least two blocks are sufficiently hydrophobic to cause the macromer to aggregate to form micelles in an aqueous continuous phase;c) the macromer comprises at least one crosslinkable group;d) the macromer comprises at least one thermally sensitive region; ande) a solution of the macromer is capable of gelling or crosslinking to produce a hydrogel with a temperature dependent volume.