Patent ID: 8691999
Filing Date: 2014-04-08
Classification: A61P,C07D

Abstract:
1. A process for the preparation of telmisartan of formula (I), or a pharmaceutically acceptable salt thereof: characterised in that 1H-Benzimidazole-2-n-propyl-4-methyl-6-(1′methyl benzimidazole-2′yl) of formula (II) and methyl-4-(bromomethyl)biphenyl-2-carboxylate of formula (III) are subjected to condensation and hydrolysis in a single step: followed by pH adjustment using an aqueous acid, wherein intermediate compounds of formulae (II) and (III) are reacted in dimethyl sulphoxide in the presence of a base, wherein further to pH adjustment telmisartan is extracted into dichloromethane and then isolated from acetone, and which prepares telmisartan Form A.