Patent ID: 7741343
Filing Date: 2010-06-22
Classification: A61P,C07D

Abstract:
1. A method for the treatment of psychoses, schizophrenia, depression, anxiety states, dementia, Alzheimer's disease, Lewy bodies dementia, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, Tourette's syndrome, learning and memory restrictions, bulimia, anorexia nervosa, eating disorders, compulsive behavior, premenstrual syndrome, age-induced memory impairment, strokes, brain damage by toxic compounds or amelioration of withdrawal symptoms in nicotine dependence, in which binding to nicotinic acetylcholine receptors results in an improvement in the clinical picture, comprising administering to a host in need thereof an effective amount of a compound of Formula I in which R R R R R A is a linear or branched alkyl group having from 1 to 10 carbon atoms, Ar is phenyl, naphthyl or biphenyl, each of which is unsubstituted or monosubstituted or polysubstituted by Hal, A, OR cycloalkyl is cycloalkyl having from 3 to 10 carbon atoms, Hal is F, Cl, Br or I, Het is a saturated, unsaturated or aromatic monocyclic or bicyclic heterocyclic radical having from 5 to 10 ring members, which may contain from 1 to 4 N and/or from 1 to 4 S and/or from 1 to 4 O atoms, and in which the heterocyclic radical may be monosubstituted, disubstituted or trisubstituted by Hal, A, —[C(R Het n is 0, 1, 2, 3, 4, 5, 6, 7 or 8, m is 1 or 2, o is 0, 1, 2, 3 or 4, p is 1, 2, 3, 4, 5, 6, 7 or 8, or a physiologically acceptable salt thereof.