Patent ID: 9142394
Filing Date: 2015-09-22
Classification: H01J

Abstract:
1. A tandem quadrupole mass spectrometer having front-stage and rear-stage quadrupole mass filters with a collision cell for fragmenting an ion in between, the tandem quadrupole mass spectrometer having a function of performing a multiple reaction monitoring (MRM) measurement condition optimization for searching for an optimum MRM measurement condition for one or a plurality of compounds while conducting an MRM measurement of a sample, and the tandem quadrupole mass spectrometer comprising: a) a preferred ion registry for registering a mass-to-charge ratio of one or a plurality of product ions to be preferentially selected as a target, for each precursor ion, as a measurement condition for optimizing the MRM measurement condition; and b) an MRM measurement condition optimizer for performing the MRM measurement condition optimization for a target precursor ion originating from one compound by retrieving information about a preferred product ion for the precursor ion from the preferred ion registry, and if the preferred product ion is detected as a product ion for the precursor ion, controlling each section of the mass spectrometer so as to perform the MRM measurement condition optimization for a combination of the mass-to-charge ratios of the precursor ion and the preferred product ion and obtain an optimum value of a control parameter.