Patent ID: 6841569
Filing Date: 2005-01-11
Classification: A61K,A61P,C07D

Abstract:
1. A compound represented by the formula: wherein A is a heterocyclic moiety selected from those represented by the formulae optionally substituted by one or more substituents selected from the group consisting of alkyl, aryl, halogen, trihalomethyl, trihalomethoxy, trialkylsilyl, S(O)R, SO 2 R, SO 2 NRR′, SO 3 R, SR, NO 2 , NRR′, OR, CN, C(O)R, OC(O)R, NHC(O)R, CO 2 R and CONRR′, wherein R and R′ are independently hydrogen, alkyl or aryl; B 1 and B 2 are independently hydroxy or OCONR 1 R 2 , provided that B 1 and B 2 are not simultaneously hydroxy,: and R 1 and R 2 are independently selected from the group consisting of hydrogen, hydroxy, alkyl, alkoxy, alkylaryl, arylalkyl, aryl and aryloxy, and each of R 3 , R 4 and R 5 is independently selected from the group consisting of hydrogen, halogen, trihalomethyl, alkyl and aryl, and their enantiomers, enantiomeric mixtures thereof, and pharmaceutically acceptable salts thereof.