Patent ID: 8431346
Filing Date: 2013-04-30
Classification: C12Q

Abstract:
1. A method of diagnosing a deletion mutation in a bovine genome, said method comprising: obtaining a DNA sample from the bovine; analyzing said DNA sample to determine the presence or absence of a deletion mutation, wherein said deletion mutation comprises deletion of SEQ ID NO:3 and said deletion mutation is at a breakpoint between nucleotides 429 and 430 or between nucleotides 445 and 446 of SEQ ID NO:2; and diagnosing the bovine as a carrier of Arthrogryposis Multiplex (AM) when the analyzed DNA has the deletion mutation or diagnosing the bovine as not a carrier of AM when the analyzed DNA does not have the deletion mutation; wherein the step of analyzing the DNA sample is by polymerase chain reaction (PCR).