Patent ID: 6387382
Filing Date: 2002-05-14
Classification: A61K,A61Q,Y10S

Abstract:
A skin preparation comprising,a) an oil phase including; (i) a siloxane polymer, selected from the group consisting of dimethicone, trimethylsiloxysilicate, and mixtures of dimethicone and trimethylsiloxysilicate, in an amount of at least about 2% by weight of the total skin preparation; (ii) a cyclic silicone in an amount of at least about 1% by weight of the total skin preparation; wherein the siloxane polymer and cyclic silicone are present in a ratio by weight in the range of from about 2:1 to about 7:1; (iii) one or more emulsifiers in an amount of at least about 1.5% by weight of the total skin preparation; (iv) one or more antioxidants in an amount of at least about 0.1% by weight of the total skin preparation; and (v) one or more emollients in an amount of at least about 2% by weight of the total skin preparation; (vi) one or more oil soluble therapeutic agents in an amount of at least 0.001% by weight of the total skin preparation; and b) an aqueous phase including; (i) one or more humectants in an amount of from at least about 0.1% to about 8% by weight of the total skin preparation; (ii) one or more rheology modifiers in an amount of at least about 0.1% by weight of the total skin preparation; (iii) one or more thickeners in an amount of at least about 0.1% by weight of the total skin preparation; (iv) one or more water soluble therapeutic agents in an amount of at least 0.1% by weight of the total skin preparation; and (v) water.