Patent ID: 8062865
Filing Date: 2011-11-22
Classification: C07K

Abstract:
1. A dicistronic message for producing an a recombinant antibody molecule, in which the upstream cistron contains DNA coding for the light chain of the recombinant antibody and the downstream cistron contains DNA coding for the corresponding heavy chain, characterised in that the two cistrons are linked by an intergenic sequence (IGS), wherein the IGS is selected from IGS5 (SEQ ID NO: 12), IGS8 (SEQ ID NO: 13), IGS9 (SEQ ID NO:14), IGS10 (SEQ ID NO:15), IGS11 (SEQ ID NO:16), IGS12 (SEQ ID NO:17), IGS 13 (SEQ ID NO:18), IGS14 (SEQ ID NO: 19), IGS15 (SEQ ID NO:20), IGS16 (SEQ ID NO:21), IGS17 (SEQ ID NO:22) and IGS18 (SEQ ID NO:23).