Patent ID: 6610726
Filing Date: 2003-08-26
Classification: A61K

Abstract:
A pharmaceutical composition comprising an effective HGF/SF activity modulating amount of a compound with the general formula: whereinR1 is SO2Alkyl, wherein alkyl is a C1 to C4 a straight chain, branched or a cycloalkyl group; SO2-Aryl wherein aryl is halo, C1 to C4 alkyl or alkoxy substituted phenyl; COAlkyl, wherein alkyl is C1 to C6 straight chain alkyl, branched alkyl, or cycloalkyl; COAryl, wherein Aryl is phenyl substituted with halo, C1 to C4 alkyl or alkyloxy, trifluoromethyl, difluormethyl, nitro, hydroxy, amine, or another aryl or another heteroaryl; CONHAlkyl wherein alkyl is C1 to C6 straight chained alkyl, branched alkyl, or cycloalkyl; or CONHAryl, wherein aryl is a phenyl substituted with halo, C1 to C4 alkyl or C1 to C4 alkyloxy; and R3 is CHCH-heteroaryl; phenoxyphenyl; heteroaryl; or aryl substituted heteroaryl; and a pharmaceutically acceptable carrier, excipient, or diluent.