Patent ID: 9220488
Filing Date: 2015-12-29
Classification: A61B,A61F,A61M,A61N

Abstract:
1. A method of treating an adventitia of a blood vessel within a patient, comprising: inserting a targeting catheter into a patient; positioning the targeting catheter proximate to the adventitia of the blood vessel; emitting at least one signal from the targeting catheter from within the patient; receiving the at least one signal with a plurality of receivers on a therapeutic applicator that is positioned external to the patient, wherein the therapeutic applicator comprises one or more therapeutic ultrasound transducers and the plurality of receivers are spaced apart from each other on the therapeutic applicator; determining an acoustic time-of-flight from the targeting catheter to the therapeutic applicator based at least in part on the at least one signal; determining a location of a portion of the targeting catheter relative to the therapeutic ultrasound applicator based at least in part on the acoustic time-of-flight determination; adjusting a focus of the one or more therapeutic ultrasound transducers based on the determined location of the portion of the targeting catheter, wherein the focus is adjusted to target the adventitia of the blood vessel; and emitting a dose of focused ultrasound from the therapeutic applicator to the adventitia of the blood vessel.