Patent ID: 6420576
Filing Date: 2002-07-16
Classification: C07C,C09B

Abstract:
A process for preparing an arylaminohydroxy-anthraquione of formula (I) whereinR1, R2, R3 and R4 are independently hydrogen, hydroxyl or NHâ€”Ar, provided that at least one of R1 to R4 is OH and at least one of R1 to R4 is â€”NHâ€” Ar, and Ar is naphthyl; naphthyl substituted by one or more identical or different substituents selected from the group consisting of alkyl and halogen; phenyl; and/or phenyl substituted by one or more identical or different substituents selected from the group consisting of cyano, carboxyl, nitro, alkylsulphonyl, carbonyl, sulfo, alkylaminocarbonyl, alkylcarbonyl-amino, alkyl, cycloalkyl, alkoxy, trifluoromethyl, halogen and aryl, which in turn may be substituted by the radicals mentioned above for naphthyl and phenyl, â€ƒwhich comprises reacting a chlorohydroxyanthraquinone selected from the group consisting of 4,8-dichloro-1,5-dihydroxyanthrachinone, 4,5,-dichloro-1,8-dihydroxyanthrachinone, 5,8-dichloro-1,4-dihydroxyanthrachinone, with an amine of formula (III), H2Nâ€”Arâ€ƒâ€ƒ(III), â€ƒin an amount of 1.1 to 2 moles of amine of formula (III) for each chlorine atom in the chlorohydroxyanthraquinone, wherein the reaction is carried out in an inert solvent comprising a member selected from the group consisting of N-methyl-pyrrolidone, chlorobenzene, dichlorobenzene, 1,2,4-trichlorobenzene, xylene, nitrobenzene and phenol in the presence of a base comprising a member selected from the group consisting of alkali and alkaline earth metal carbonates, alkali metal acetates and alkali metal phosphates.