Patent ID: 7094545
Filing Date: 2006-08-22
Classification: A61K

Abstract:
1. A method for manufacturing a pharmaceutical composition as a solid dosage form comprising desmopressin acetate, as a therapeutically active ingredient, wherein said method comprises the steps of: i) mixing desmopressin acetate and an excipient, diluent or carrier, or mixture thereof, optionally in the presence of a wetting agent, wherein at least one of said excipient, diluent and carrier is a disaccharide, wherein said disaccharide has an average particle size in the range of from 70 to 500 μm; ii) subjecting the resulting mixture to formation of a granulate, optionally in the presence of a wetting agent, suitable for compression into said solid dosage form; iii) optionally performing said mixing and/or formation of a granulate in the presence of at least one additive selected from a disintegrating agent, lubricant, binder, flavoring agent, preservative, colorant and a mixture thereof; iv) optionally drying said granulate; v) compressing said granulate into said solid dosage form, wherein said solid dosage form is a tablet.