Patent ID: 9079890
Filing Date: 2015-07-14
Classification: A61P,C07D

Abstract:
1. A compound of formula: where: L is O or S; R Ar hetAr hetAr hetAr R hetAr R Ar hetAr Ar hetAr hetAr 6 is a 9-10 membered bicyclic heteroaromatic ring having 2-3 heteroatoms independently selected from N, S and O (provided the ring does not contain an O—O bond) which is optionally substituted with one or more groups independently selected from (1-6C)alkyl, F, Br, Cl, CF 3 , CN, OH, —O-(1-6C alkyl), C(═O)OH, C(═O)O(1-6C alkyl) and C(═O)NH(1-3C alkyl)N(1-3 Calkyl) 2 ; R hetCyc provided that the compound is not: 1-(5-chloro-3-phenoxypyridin-2-yl)thiourea, 1-(5-bromo-3-phenoxypyridin-2-yl)thiourea, 1-(5-bromo-3-(4-fluorophenoxy)pyridin-2-yl)thiourea, 1-(5-bromo-3-(phenylthio)pyridin-2-yl)thiourea, 1-(5-bromo-3-(4-cyanophenoxyl)pyridin-2-yl)thiourea, or 1-(3-(2-bromo-4-fluorophenoxy)-5-(3-methoxyphenylthio)pyridin-2-yl)thiourea.