Patent ID: 8580849
Filing Date: 2013-11-12
Classification: A61K,A61Q,C08J

Abstract:
1. A process for producing a hydrous gel, comprising preparing a mixture containing at least two polymers comprising acrylic acid/sodium acrylate copolymer and at least one of polyacrylic acid and sodium polyacrylate crosslinked with an alumina magnesium hydroxide, and water, and at least one ascorbic acid compound selected from the group consisting of ascorbic acid, ascorbic acid-2-phosphoric ester, ascorbic acid-2-pyrophosphoric ester, ascorbic acid-2-triphosphoric ester, ascorbic acid-2-polyphosphoric ester, ascorbic acid-2,3-diphosphoric ester, ascorbic acid-2,6-diphosphoric ester, ascorbic acid-2-sulfuric ester, ascorbic acid-6-palmitic ester, ascorbic acid-2,6-palmitic ester, ascorbic acid-2-glucoside, ascorbic acid-2-O-glucoside-6-palmitic ester, ascorbic acid-5,6-benzylidene, ascorbic acid-5,6-propylidene and their metal salts, ammonium salts and alkyl- or hydroxyalkyl-substituted ammonium salts, and heating said mixture at 25 to 65° C., wherein the pH when said hydrous gel is 100-fold diluted with purified water is adjusted to 6.5 to 8.5.