Patent ID: 7595335
Filing Date: 2009-09-29
Classification: A61K

Abstract:
1. A pharmaceutical composition comprising 5 to 25% of a salt of idazoxan, 10 to 40% of microcrystalline cellulose, 0.1 to 5% of lubricant, 0.1 to 0.5% of colloidal silica and 25 to 90% of lactose, with respect to the total mass; wherein said idazoxan is the polymorph of form I characterized by an X-ray diffraction pattern comprising characteristic peaks at 4.0200, 6.6400, 6.9000, 7.0800, 8.0800, 9.0000, 9.9600, 10.8400, 11.7200, 12.1400, 12.3800, 12.9800, 13.3000, 13.5200, 14.9000, 15.0600, 15.2400 and 21.4000 degrees θ, and a differential thermal analysis thermogram exhibiting a single maximum value at approximately 207.5±0.2.