Patent ID: 6156851
Filing Date: 2000-12-05
Classification: A61M,B01D,B01J,C08F,Y10T

Abstract:
A material for purification of physiological fluids of organism, comprising a porous hydrphobic divinylbenzene copolymer which has a size, a shape, and a structure providing removal of toxic compounds from a physiological liquid and which initially has surface exposed vinyl groups in which thereafter the vinyl groups are chemically modified to form different surface exposed functional groups, which are hydrophilic and biocompatible wherein the said modification comprises methods, selected from the group(A) grafting hydrophilic polymer chains by a radical polymerization of 2-hydroxyethyl methacrylate, N-vinylpyrrolidone or N-vinylcaprolactam,(B) oxidation of the vinyl groups to epoxy groups with the subsequent reaction of the epoxy groups with water, ethylene glycol, amines or 2-aminoethanol, and(C) depositing high-molecular weight hemicompatible poly(trifluoroethoxy)phosphazene onto the surface of a polymer.