Patent ID: 6159997
Filing Date: 2000-12-12
Classification: A61K,A61P

Abstract:
A method for the prevention or treatment of arteriosclerosis or xanthoma, which method comprises administering to a patient suffering from or susceptible to arteriosclerosis or xanthoma, a first agent selected from the group consisting of HMG-CoA reductase inhibitors and a second agent selected from the group consisting of thiazolidinedione insulin sensitizers, said first and second agents being administered together in a synergistic mixture or individually in amounts and within such a period as to act synergistically together, with the proviso that, when the first agent is pravastatin, the second agent is not troglitazone and wherein the HMG-CoA reductase inhibitors are selected from the group consisting of pravastatin, lovastatin, simvastatin, fluvastatin, rivastatin and atorvastatin.