Patent ID: 6410505
Filing Date: 2002-06-25
Classification: C07D

Abstract:
A compound having the formula: which is a mixture of stereoisomers, wherein:R and Râ€² are the same or different and are: a straight-chain or branched chain alkyl, CnHkXmYp where X is a Group VIA element selected from the group O, S and Se, Y is a Group VA element selected from the group N, P and As (n=2-200, 1&lE;m&lE;n, 1&lE;p&lE;n, 2nmonocyclic, polycyclic, fused-ring, bridged ring or spirocyclic alicyclic alkyl CnH2q+p+1XmYp where X is a Group VIA element selected from the group consisting O, S and Se, Y is a Group VA element selected from the group consisting of N, P and As (n=2-200, qa straight-chain or branched chain alkyl, CnHkXmYpArr where X is a Group VIA element selected from the group consisting O, S and Se, Y is a Group VA element selected from the group consisting of N, P and As, Ar is an aryl group derived from an aromatic compound selected from the group consisting of benzene, pyridine, furan, pyrrole, thiophene, indole, imidazole, oxazole, isozazole, thiazole, benzofuran, benzothiophene, benzimidazole, quinoline, isoquinoline, naphthalene, anthracene, acridine, phenanthrene and their alkylated, halogenated, nitrated or sulfonated derivatives (n=2-200, 1&lE;m&lE;n, 1&lE;p&lE;n, 2na straight-chain or branched chain alkyl, CnHkXmYpAa where X is a Group VIA element selected from the group consisting of O, S and Se, Y is a Group VA element selected from the group consisting of N, P and As, A is a substituent selected from the group consisting of F, Cl, Br, I, SiZ3, BZ2 or AlZ2, Z is selected from the group consisting of F, Cl, Br, I, OH, OCsH2t+1 (n=2-200, 1&lE;m&lE;n, 1&lE;p&lE;n, 2na straight-chain or branched chain alkyl, CnHkXmYpBb where X is a Group VIA element selected from the group consisting O, S and Se, Y is a Group VA element selected from the group consisting of N, P and As, A is a poly(&agr;-aminoacid) containing up to 300 residues, (n=2-200, 1&lE;m&lE;n, 1&lE;p&lE;n, 2nQ is: a straight-chain or branched chain alkyl, CnHkXmYp where X is a Group VIA element selected from the group consisting O, S and Se, Y is a Group VA element selected from the group consisting of N, P and As (n=2-200, 1&lE;m&lE;n, 0&lE;p&lE;n, 2nmonocyclic, polycyclic, fused-ring, bridged ring or spirocyclic alicyclic alkyl CnH2q+pXmYp where X is a Group VIA element selected from the group consisting O, S and Se, Y is a Group VA element selected from the group consisting of N, P and As (n=2-200, qa straight-chain or branched chain alkyl, CnHkXmYpArr where X is a Group VIA element selected from the group consisting O, S and Se, Y is a Group VA element selected from the group consisting of N, P and As, Ar is an aryl group derived from an aromatic compound selected from the group consisting of benzene, pyridine, furan, pyrrole, thiophene, indole, imidazole, oxazole, isozazole, thiazole, benzofuran, benzothiophene, benzimidazole, quinoline, isoquinoline, naphthalene, anthracene, acridine, phenanthrene and their alkylated, halogenated, nitrated or sulfonated derivatives (n=2-200, 1&lE;m&lE;n, 0&lE;p&lE;n, 2na straight-chain or branched chain alkyl, CnHkXmYpAs where X is a Group VIA element selected from the group consisting of O, S and Se, Y is a Group VA element selected from the group consisting of N, P and As, A is a substituent selected from the group consisting of F, Cl, Br, I, SiZ3, BZ2 or AlZ2, Z is selected from the group consisting of F, Cl, Br, I, OH, OCsH2t=1 (n=2-200, 1&lE;m&lE;n, 0&lE;p&lE;n, 2na straight-chain or branched chain alkyl, CnHkXmYpBb where X is a Group VIA element selected from the group consisting O, S and Se, Y is a Group VA element selected from the group consisting of N, P and As, B is a poly(&agr;-aminoacid) containing up to 300 residues, (n=2-200, 1&lE;m&lE;n, 0&lE;p&lE;n, 2nor pharmaceutically acceptable salts thereof.