Patent ID: 8518546
Filing Date: 2013-08-27
Classification: C07D,C09K,G02B,G03C,Y10T

Abstract:
1. A compound represented by the following Formula I, wherein, (A) Ring-A is selected from unsubstituted aryl, substituted aryl, unsubstituted fused ring aryl, substituted fused ring aryl, unsubstituted heteroaryl, and substituted heteroaryl; (B) (i) m is selected from 0 to a total number of positions to which R 1 can be bonded to Ring-A, and R 1 , for each m, is independently selected from, L 2 as described hereinafter, and a chiral or achiral group selected from formyl, alkylcarbonyl, alkoxycarbonyl, aminocarbonyl, arylcarbonyl, aryloxycarbonyl, aminocarbonyloxy, alkoxycarbonylamino, aryloxycarbonylamino, boronic acid, boronic acid esters, cycloalkoxycarbonylamino, heterocycloalkyloxycarbonylamino, heteroaryloxycarbonylamino, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, halogen, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted alkoxy, optionally substituted heteroalkyl, optionally substituted heterocycloalkyl, and optionally substituted amino, and (ii) n is selected from 0 to 3, and R (C) R 3 and R 4 are each independently selected from, hydrogen, hydroxyl, and a chiral or achiral group selected from optionally substituted heteroalkyl, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted cycloalkyl, optionally substituted heterocycloalkyl, halogen, optionally substituted amino, carboxy, alkylcarbonyl, alkoxycarbonyl, optionally substituted alkoxy, and aminocarbonyl, or one of R R (D) B and B′ are each independently selected from hydrogen, L 3 as described hereinafter, halogen, and a chiral or achiral group selected from metallocenyl, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted heteroalkyl, optionally substituted alkoxy, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted heterocycloalkyl, and optionally substituted cycloalkyl, or B and B′ taken together with any intervening atoms form a group selected from optionally substituted cycloalkyl and optionally substituted heterocycloalkyl; and (E) L 1 , L 2 and L 3 are each independently selected from a chiral or achiral lengthening group represented by the following Formula II, wherein, (i) Q (ii) c, d, e, and f are each independently an integer selected from 0 to 20, inclusive; and S (1) —(CH (2) —N(Z)—, —C(Z)═C(Z)—, —C(Z)═N—, —C(Z′)—C(Z′)- or a single bond, wherein Z is independently chosen for each occurrence from hydrogen, C (3) —O—, —C(O)—, —N═N—, —S—, —S(O)—, —S(O)(O)—, —(O)S(O)—, —(O)S(O)O—, —O(O)S(O)O—, or straight-chain or branched C provided that when two spacer units comprising heteroatoms are linked together the spacer units are linked so that heteroatoms are not directly linked to each other, and provided that when S (iii) P is chosen from: hydroxy, amino, C (iv) d′, e′ and f′ are each independently chosen from 0, 1, 2, 3, and 4, provided that a sum of d′+e′+f′ is at least 2.