Patent ID: 6663869
Filing Date: 2003-12-16
Classification: A61K,A61P,C07K

Abstract:
A homogeneous polyoxime composition, in which polyoxime molecules present in said composition comprise a baseplate organic molecule, said baseplate organic molecule being a polypeptide, and wherein said baseplate organic molecule is linked to at least two second organic molecules, which may be the same or different from one another, the linkages between said baseplate organic molecule and said second organic molecules being oxime linkages formed by reaction of an orthogonal reactive group on each of said second organic molecules with at least two complementary orthogonal reactive groups on said baseplate organic molecule, said orthogonal reactive group and said complementary orthogonal reactive group being selected from the group consisting of a keto group, an aldehyde group, or an amino-oxy group, and wherein complementary orthogonal reactive group on said baseplate organic molecule comprises an amino acid residue having a side chain comprising at least one of said complementary orthogonal reactive groups.