Patent ID: 8143010
Filing Date: 2012-03-27
Classification: C07K,Y10S

Abstract:
1. A method to detect susceptibility to a prostate neoplastic condition in a subject, comprising: (a) measuring the expression level of PAMP RNA in said test sample obtained from said subject by selective hybridization with a PAMP nucleic acid probe of sufficient length to hybridize selectively to the coding region of SEQ ID NO:1 or its full complement, thereby determining the expression level of PAMP in said test sample; and (b) comparing said expression level of PAMP RNA in the test sample to the expression level of PAMP RNA in a standardized control sample, wherein said test sample is prostate tissue, blood, serum, urine or semen, wherein a test sample expression level of PAMP RNA of 2-fold or more greater than the expression level of PAMP RNA in said standardized control sample indicates susceptibility to a prostate neoplastic condition.