Patent ID: 9126978
Filing Date: 2015-09-08
Classification: A61K,A61P,C07D,Y02A

Abstract:
1. A compound described by a formula selected from the group consisting of: or a pharmaceutically acceptable salt thereof; wherein R wherein R wherein R wherein R wherein R wherein R —OH, fluoroalkyl, —SO 2 R 28 , —SO 2 N(R 7′ ) 2 , —OR 7′ , —N(R 7′ ) 2 , —CON(R 7′ ) 2 , —NHCOR 7′ , —NHSO 2 R 7′ , alkyl, mono-substituted alkyl, di-substituted alkyl, tri-substituted alkyl; wherein R 7′ is selected from the group consisting of halogen, H, alkyl, mono-substituted alkyl, di-substituted alkyl, tri-substituted alkyl, aryl, mono-substituted aryl, di-substituted aryl, tri-substituted aryl, cycloaliphatic, mono-substituted cycloaliphatic, di-substituted cycloaliphatic, and tri-substituted cycloaliphatic; wherein R wherein R 25 , R 26 , R 27 , and R 28 are independently selected from the group consisting of hydrogen, alkyl, wherein no more than three of R 25 , R 26 , R 27 , and R 28 can be hydrogen; wherein the stereochemical configuration at a stereocenter in said compound is R, S, or a mixture thereof; wherein each substituted alkyl, substituted cycloaliphatic, or substituted aryl independently has at least one of the hydrogen atoms replaced by a halogen, an amino, a hydroxy, a nitro, a lower aliphatic, an aryl, or a cycloaliphatic.