Patent ID: 8921373
Filing Date: 2014-12-30
Classification: A61P,C07D

Abstract:
1. A compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein X is O, S, N—CN, or N—OR W is N; the dashed line denotes the absence of a bond, and R R each R each R R Z Z Z Ar each R each R Y wherein no more than one of Y Y E is ═O, ═S, ═C(R each R each R each R each R each R R each halo is independently —F, —Cl, —Br, or —I; n is the integer 0, 1, or 2; m is the integer 0, 1, or 2; k is the integer 1 or 2; q is the integer 0, 1, 2, 3, or 4; s is the integer 0, 1, 2, 3, 4, or 5; t is the integer 0, 1, 2, or 3; u is the integer 0, 1, 2 or 3; each b is independently 1 or 2; and c is the integer 0, 1, or 2.