Patent ID: 6329202
Filing Date: 2001-12-11
Classification: A61K,A61P,C07K

Abstract:
A method for immunizing an animal against a viral infection comprising administering to a subject an effective amount of an epitope or an anti-idiotype antibody of said epitope, wherein said epitope is of a complex formed between two members of a binding couple and is a member of a group consisting of:(i) an epitope consisting of a sequence in a member of a binding couple, which becomes substantially more accessible to antibodies or resumes a new conformation after binding of the two members to one another,(ii) an epitope consisting of two or more sequences in a member of binding couple which upon binding of the two members, become closely associated to form an antigenic epitope, and(iii) an epitope consisting of two or more sequences, at least one being in one member of a binding couple, and at least one other being in the other member of the binding couple and upon binding of the two members, said two or more amino acid sequences become closely associated with one another to form an antigenic epitope;said antigenic epitope being immunogenic.