Patent ID: 7897794
Filing Date: 2011-03-01
Classification: C07D

Abstract:
1. A method of purifying HMF from a mixture containing reactants and products of HMF synthesis from fructose, comprising, contacting a first non-functional polymeric resin that preferentially adsorbs HMF relative to fructose with an aqueous solution containing the mixture of reactants and products of HMF synthesis for a time sufficient to adsorb a majority of HMF from the mixture onto the non-functional polymeric resin; contacting the first non-functional polymeric resin with water until a majority of fructose from the mixture is removed from the non-functional polymeric resin while a majority of the HMF from the mixture remains adsorbed to the non-functional polymeric resin; contacting the first non-functional polymeric resin with an organic solvent in an amount sufficient to desorb the majority of HMF from the non-functional polymeric resin; and collecting the desorbed HMF in a first eluted solution containing the organic solvent.