Patent ID: 6713651
Filing Date: 2004-03-30
Classification: C07B,C07C,C07D,C07K,C40B,G01N

Abstract:
A compound of Formula (II): whereinAr1 and Ar3 are independently selected from the group consisting of aryl, heteroaryl, and heterocyclyl; Ar2 is selected from the group consisting of (a) phenylene, wherein W and X are attached at the 1,2-, 1,3- and 1,4-positions of the phenylene ring; (b) cyclohexylene optionally substituted with methyl, wherein W and X are attached at the 1,3- and 1,4-positions of the cyclohexylene ring; and piperazinylene, wherein W and X are attached at the 1,4-positions of the piperazinylene ring; X is a bond; and Q is selected from the group consisting of â€”(CH2)3â€”Oâ€”(CH2)6â€”NHâ€”CH2â€”CH(OH)â€”, â€”Oâ€”(CH2)â€”CH(OH)â€”(CH2)â€”NHâ€”(CH2)â€”CH(OH)â€”, and â€”NHâ€”CH2â€”CH(OH)â€”CH2â€”Oâ€”; W is selected from the group consisting of a covalent bond, alkylene, and a substituted alkylene group wherein one or more of the carbon atoms in the alkylene group is optionally replaced by â€”Oâ€”; or a pharmaceutically acceptable salt thereof.