Patent ID: 6579902
Filing Date: 2003-06-17
Classification: A61P,C07H

Abstract:
A compound of the formula whereinR1 is selected from the group consisting of acyclic and cyclic alkyl, alkenyl, alkynyl, O-alkyl, O-alkenyl and O-alkynyl of up to 8 carbon atoms unsubstituted or substituted by at least one halogen and, optionally interrupted by oxygen or sulfur or nitrogen, unsubstituted or substituted aryl or aralkyl of up to 18 carbon atoms, an unsubstituted or substituted mono or polycyclic aromatic or non-aromatic heterocyclic, â€”NH2, â€”NHalk1 and â€”NHOalk2 alk1, and alk2 are alkyl of up to 8 carbon atoms, R2 is hydrogen or halogen, R3 is selected from the group consisting of hydrogen, alkyl of up to 8 carbon atoms, and halogen, R4 is selected from the group consisting of â€”NHRâ€² and â€”NHORâ€³ in which Râ€² or Râ€³ are individually selected from the group consisting of acyclic and cyclic, alkyl, alkenyl and alkynyl of up to 8 carbon atoms and unsubstituted or substituted aryl of up to 14 carbon atoms, R5 is hydrogen or alkoxy of up to 8 carbon atoms, R6 is alkyl or CH2O-alkyl, in which alkyl is alkyl of up to 8 carbon atoms, R7 is a hydrogen or a alkyl of up to 8 carbon atoms or R6 and R7 together with the carbon which carries them form a ring and its pharmaceutical addition salts with bases.