Patent ID: 6849739
Filing Date: 2005-02-01
Classification: A61P,C07D

Abstract:
1. A compound of formula (VIIa), formula (VIIb) or formula (VIIo): wherein: A is —R X and Y are aboth N, U is C(R or X and Z are aboth N, U is C(R or U and X are aboth N, Z and Y is C(R or Y and Z are aboth N, U is C(R V is N(R Q is chosen from the group consisting of a direct bond, —C(O)—, —O—, —C(═N—R m is zero or an integer from 1 to 4; n is zero or an integer from 1 to 3; q is zero or one; r is zero or one, provided that when Q and V are heteroatoms, m, q, and r cannot all be zero; when A is —OR t is zero, one or two;  is an optionally substituted N-heterocyclyl;  is an optionally substituted carbocyclyl or optionally substituted N-heterocyclyl; each R or R R or when Q is —N(R or -Q-R R provided that when A is —R R R each R each R each R each R each R R each R each R21 is independently hydrogen, alkyl, cycloalkyl, optionally substituted aryl, optionally substituted aralkyl, —C(O)R or R or R each R R as a single stereoisomer or mixture thereof, or a pharmaceutically acceptable salt thereof.