Patent ID: 8809381
Filing Date: 2014-08-19
Classification: A61K,A61P,C07D

Abstract:
1. A compound having the general formula I wherein R 1 can be an optionally substituted an optionally substituted tetrahydropyridine, an optionally substituted azepane or an optionally substituted tetrahydroisoquinoline in which the optional substituents are on the aromatic moiety or an optionally substituted isoindoline-1,3-dione; R 2,3,4,5 can each independently be any one or combinations of the following moieties, hydrogen, cyano, nitro, acyl, alkyl, amido, azido, isothiocyanate, isocyanate, optionally substituted anilino, ethers, sulfonamides, thioacyl, nitro, aromatic, heterocyclic, olefinic, acetylene, deuterium, or tritium; “n” can be 1 to 5 carbons in length and wherein the moiety bridging R 1 and N can be optionally substituted alkylene, optionally substituted alkenylene or optionally substituted alkynylene with the exclusion of the following compounds: and stereoisomers, or pharmaceutically acceptable salts thereof.