Patent ID: 9034337
Filing Date: 2015-05-19
Classification: A61K,A61P,C07K

Abstract:
1. A method of reducing the risk of, lessening the severity of, delaying the outset of or treating a disease characterized by Lewy bodies or alpha-synuclein aggregation in the brain, the method comprising: administering to a patient having or at risk of the disease an immunogenic fragment of alpha-synuclein consisting of 5-9 contiguous residues from between residues 118-126 of human alpha synuclein (SEQ ID NO:1) effective to induce an immunogenic response comprising antibodies that specifically bind to an epitope within residues 118-126 of SEQ ID NO: 1, thereby reducing the risk of, lessening the severity of, delaying the outset of or treating the disease.