Patent ID: 6077438
Filing Date: 2000-06-20
Classification: B01J,C40B,G01N

Abstract:
A method for measuring the masses of compounds present in a plurality of fluid samples during fraction collection, comprising:simultaneously separating each fluid sample into sequentially eluted isolated compounds by passing the fluid samples through parallel fluid separation devices,diverting a first portion of each of the sequentially eluted isolated compounds into a mass spectrometer, thereby determining the molecular weight of each isolated compound in sequence;diverting a second portion of each of the sequentially eluted compounds into an evaporative light scattering detector, thereby determining the total masses of each isolated compound passing therethrough in sequence;fraction collecting at least one of the isolated compounds into a fraction collector; andcalculating the total masses of the isolated compounds in the fraction collector during fraction collection on the basis of the second portion of each of the isolated compounds diverted into the evaporative light scattering detector during a period of fraction collection.