Patent ID: 6037472
Filing Date: 2000-03-14
Classification: A61P,C07C,C07D,C07F

Abstract:
A compound of the formula ##STR44## wherein R.sup.1 is mercapto, acetylthio, carboxy, hydroxycarbamoyl, N-hydroxyformamide, alkoxycarbonyl, aryloxycarbonyl, aralkoxycarbonyl, benzyloxycarbamoyl or a group of the formula ##STR45## where R.sup.6 is aryl, pyridyl or thiazolyl; R.sup.2 is biphenyl;R.sup.3 is alkyl, cycloalkyl, aralkyl, alkylpyridyl or alkylthiazolyl;R.sup.7 is 4-pyridyl or-optionally substituted phenyl;X is a group of the formula --(CH.sub.2).sub.m --Y--(CH.sub.2).sub.n --, where:Y is O, S, or a single bond,m is an integer from 0 to 4,n is an integer from 0 to 4, andm+n is an integer from 0 to 4; andp is 0;wherein the compound contains pyridyl and optionally thiazolyl as the only heterocyclics in the compound or a pharmaceutically acceptable salt thereof.