Patent ID: 7482471
Filing Date: 2009-01-27
Classification: C07D

Abstract:
1. A process for preparation of 1-[9H-carbazol-4-yloxy]-3-[{2-(2-(methoxy)phenoxy)-ethyl}-amino]-propan-2-ol, a compound of formula 1 in racemic form or in the form of optically active R or S enantiomer or its pharmaceutically acceptable salt, comprising, a) reacting 4-(oxiranylmethoxy)-9H-carbazole, a compound of formula 2 or the R or S enantiomer thereof with a compound of formula 5,  wherein R b) subjecting the resultant compound of formula 6 to debenzylation reaction by catalytic hydrogenation to obtain the compound of formula 1, if desired converting the resultant compound of formula 1 to a pharmaceutically acceptable salt thereof.