Patent ID: 8968872
Filing Date: 2015-03-03
Classification: A23L,A23P,A23V,A61K,A61P,B01J,Y10S,Y10T

Abstract:
1. A process for preparing a microcapsule, the process comprising: (a) providing an aqueous mixture comprising (i) a biologically active loading substance and (ii) a first and a second polymer component; (b) adjusting pH, temperature, concentration, mixing speed or a combination thereof of the aqueous mixture to produce a shell material by complex coacervation of only the first and second polymer components, the shell material forming a primary shell around the loading substance, thereby producing a primary microcapsule; (c) cooling the aqueous mixture until a plurality of the primary microcapsules form an agglomeration; (d) further cooling the aqueous mixture to produce an outer shell of the shell material by complex coacervation of the first and second polymer components around the agglomeration; and (e) spray drying the aqueous mixture, to produce the microcapsule, wherein the first polymer component is gelatin and the second polymer component is polyphosphate and the microcapsule has not been crosslinked.