Patent ID: 8623336
Filing Date: 2014-01-07
Classification: A23G,A23L,A61K,A61P,A61Q,C08B,C08J,C08K,C08L

Abstract:
1. A process for the preparation of a gel having a structure of formula 1, comprising xyloglucan, and chitosan in the ratio of 1 to 6: 1 to 8 by weight, comprising the steps of: [a] preparing a slurry by dissolving a xyloglucan source in water wherein the ratio of xyloglucan source to water is in the range of 1 to 10: 10 to 20 at a pH of 2 to 10; [b] heating the slurry as obtained in step [a] at 40 to 80 degrees C. followed by cooling to a temperature of 25 to 33 degrees C. and precipitating the slurry with an alcoholic solvent selected from the group consisting of benzyl alcohol, isopropanol, isobutanol, ethanol, methanol, and n-butanol to obtain xyloglucan; [c] drying the precipitated xyloglucan as obtained in step [b] under vacuum or freeze dried to obtain powder; [d] dispersing the powdered xyloglucan as obtained in step [c] in water or a solvent selected from the group consisting of DMSO, DMF, THF, dichloromethane, hexane, benzene, acetone acetic acid, and formic acid at a pH in the range of 7 to 14 to obtain a mixture; [e] stirring the mixture as formed in step [d] with an oxidative reagent selected from the group consisting of nitric acid, nitrous oxide, cerium compounds, perchlorate, periodate, peroxide, and permanganate at a temperature of 2 to 10 degrees C. for 1 to 15 hours; [f] terminating the reaction of step [e] by adding 1 to 10 ml of a diol and purifying the liquid product by method such as dialysis or column chromatography to obtain pure oxidized sample; [g] mixing the pure oxidized sample as obtained in step [f] with 1 to 10% chitosan at a pH in the range of 1 to 7; [h] stirring the mixture as obtained in step [g] for 1 to 5 min to obtain a clear transparent chitam gel.