Patent ID: 6933304
Filing Date: 2005-08-23
Classification: A61P,C07D

Abstract:
1. A compound or a pharmaceutically acceptable salt thereof, wherein: the compound corresponds in structure to Formula I: the structure: is a thiazole or isoxazole, wherein: the thiazole or isoxazole is optionally substituted with one or more substituents independently selected from the group consisting of alkyl, haloalkyl, aryl, heteroaryl, halogen, alkoxyalkyl, aminoalkyl, hydroxy, nitro, alkoxy, hydroxyalkyl, alkylthio, amino, alkylamino, arylamino, alkylsulfonamide, acyl, acylamino, alkylsulfone, sulfonamide, allyl, alkenyl, methylenedioxy, ethylenedioxy, alkynyl, carboxamide, cyano, and —(CH each m is independently zero, 1, or 2; each R is independently selected from the group consisting of hydroxy, alkoxy, alkyl, amino, and sulfone; A wherein any such substituent is optionally substituted by one or more substituents independently selected from the group consisting of hydroxy, alkyl, alkoxy, alkoxyalkyl, alkylthio, haloalkyl, cyano, amino, alkylamino, halogen, acylamino, sulfonamide, and —COR 4 ; X X X R R R each R Z Z each R any carbon and nitrogen atoms of Z X is selected from the group consisting of —CHR Y is selected from the group consisting of —(CH R R each R p is zero or 1; as to Y Y Y Y R X R