Patent ID: 6509040
Filing Date: 2003-01-21
Classification: A61K

Abstract:
A fast dispersing solid dosage form designed to release an active ingredient rapidly in the oral cavity characterized in that said dosage form is essentially free of mammalian gelatin and comprises:a) at least one active ingredient; b) at least one modified starch at a concentration of from 20 to 90% by weight; selected from the group consisting of starches whose hydroxyl groups have been esterified, hydroxypropyl di-starch phosphate, an enzymatically modified starch, a pregelatinized di-starch phosphate, hydroxyethyl starch, a pregelatinized acetylated di-starch phosphate and a pregelatinized purified starch; and c) at least one matrix forming agent; wherein said solid dosage form has a disintegration/dispersion time of from 1-60 seconds and is obtainable by removing a solvent from a mixture comprising said active ingredient, said modified starch and said matrix forming agent.