Patent ID: 7838690
Filing Date: 2010-11-23
Classification: A61P,C07D

Abstract:
1. A method for preparing 3-O-substituted ascorbic acid represented by the following formula 1, comprising the following steps: a) Preparing 3-O-substituted-5,6-O-isopropylidene ascorbic acid represented by the following formula 4 by reacting 5,6-O-isopropylidene ascorbic acid represented by the following formula 2 with a halide represented by the following formula 3 in an organic solvent in the presence of the anion exchange resin absorbed with multi-iodine anions; and b) Deprotecting the 3-O-substituted-5,6-O-isopropylidene ascorbic acid represented by the following formula 4; [In formula 1, formula 3 and formula 4, R is C1˜C7 alkyl or alkenyl and X is halogen atom].