Patent ID: 6429229
Filing Date: 2002-08-06
Classification: A61K,A61P

Abstract:
A method for the treatment of human or animal pathologies in which the silent neurons are involved, comprising administering to a human or animal in need of same a therapeutically effective amount of a salt of the following general formula (I):(X)n1,Y,(Z)n2â€ƒâ€ƒ(I) in which:n1 and n2 represent 0 or 1, provided that when n1=0 then n2=1, and when n2=0 then n1=1, X represents a natural amino acid, provided that when n2=0 then X is a basic amino acid, Y represents a keto acid of the following formula (II): Râ€”COâ€”COOHâ€ƒâ€ƒ(II) â€ƒin which R represents an alkyl or alcanoic acid, substituted or not, of about 1 to about 10 carbon atoms, Z represents: a natural amino acid, or, a polyamine comprising at least two primary, secondary or tertiary amine functions, spaced by a linear or branched hydrocarbon chain of about 3 to 10 carbon atoms.