Patent ID: 8420653
Filing Date: 2013-04-16
Classification: A61K,A61P,C07D

Abstract:
1. A method of treatment of COPD in a mammal comprising administering an effective amount of a compound of formula (I), their tautomeric forms, stereoisomers or pharmaceutically acceptable salts, to the mammal in need thereof wherein A represents substituted or unsubstituted aryl group; B represents substituted or unsubstituted groups selected from aryl or pyridyl; X represents carbon or nitrogen atom; R represents substituted or unsubstituted groups selected from azido; halogens; linear or branched alkyl groups comprising methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, t-butyl, n-pentyl, isopentyl and hexyl; alkoxy groups comprising methoxy, ethoxy, n-propoxy, isopropoxy, n-butoxy, isobutoxy and t-butoxy; haloalkyl groups comprising dichloromethyl, difluoromethyl, trifluoromethyl and trichloromethyl; acyl groups comprising acetyl and propanoyl; cycloalkyl groups comprising cyclopropyl, cyclobutyl and cyclopentyl; amino; hydrazine; monoalkylamino; dialkylamino; acylamino groups comprising acetylamino and propanoylamino; alkylsulfonyl groups comprising methylsulfonyl, ethylsulfonyl and propylsulfonyl; alkylsulfinyl; arylsulfonyl; arylsulfinyl; alkoxycarbonyl comprising methoxycarbonyl and ethoxycarbonyl; aryloxycarbonyl; alkoxyalkyl; sulfamoyl; aryl groups comprising phenyl and naphthyl; heteroaryl groups comprising pyridyl, thienyl, furyl, pyrrolyl, pyrazolyl, oxazolyl, thiazolyl, imidazolyl, thiadiazolyl, triazolyl, tetrazolyl, pyrimidinyl, pyrazinyl, benzofuranyl, benzimidazolyl and benzothiazolyl; aryloxy; —OSO R R R R R, R