Patent ID: 6515156
Filing Date: 2003-02-04
Classification: B01J,C07B,C07C,C07F

Abstract:
A catalyst for an asymmetric hydrogenation reaction, said catalyst comprising a metal complex, said metal complex comprising a ligand and a metal;said ligand being an aminophosphine compound represented by the following formula (1) wherein each Ar represents an aryl group which may be substituted with a halogen atom, a lower alkyl group having 1 to 4 carbon atoms or an alkoxy group, with both Ar's being the same or different from each other; R1 and R2 represent hydrogen atoms, a cycloalkyl group having 5 to 7 carbon atoms, or an alkyl group having 1 to 6 carbon atoms which may be substituted with a halogen atom, a lower alkoxy group or phenyl group, with R1 and R2 being the same or different from each other, or one of R1 and R2 is a hydrogen atom and the other is â€”COR3, wherein R3 represents a cycloalkyl group having 5 to 7 carbon atoms, a lower alkyl group having 1 to 6 carbon atoms which may be substituted with a halogen atom, a lower alkoxy group or phenyl group, a substituted or unsubstituted phenyl group, or a lower alkoxy group having 1 to 6 carbon atoms which may be substituted with a cycloalkyl group having 5 to 7 carbon atoms, a halogen atoms, a lower alkoxy group or phenyl group or â€”SO2R4, wherein R4 represents a cycloalkyl group having 5 to 7 carbon atoms, an alkyl group having 1 to 6 carbon atoms which may be substituted with a halogen atom, a lower alkoxy group or phenyl group, or substituted or unsubstituted phenyl group; and n represents 0, and said metal being one or more transition metal selected from the group consisting of rhodium, ruthenium, iridium and nickel.