Patent ID: 6462016
Filing Date: 2002-10-08
Classification: A61K,C07K,Y10S

Abstract:
An isolated polypeptide which specifically binds to a receptor which maxadilan specifically binds, said polypeptide being selected from the group consisting of:a) a polypeptide comprising the amino acid sequence of Cys (1) to Ala (61) of SEQ ID No. 1, wherein at least one of the amino acid residues of Cys (1) to Cys (5) is deleted, b) a polypeptide comprising the amino acid sequence of Cys (1) to Ala (61) of SEQ ID No. 1, wherein at least one of the amino acid residues Cys (1) and Cys (5) is replaced by an amino acid(s) other than Cys, c) a polypeptide comprising the amino acid sequence of Cys (1) to Ala (61) of SEQ ID No. 1, wherein at least one of the amino acid residues of Leu (24) to Gly (44) is deleted, and d) a polypeptide comprising the amino acid sequence of Cys (1) to Ala (61) of SEQ ID No. 1, wherein at least one of the amino acid residues of Cys (14) and Cys (51) is replaced by an amino acid(s) other than Cys.