Patent ID: 8951505
Filing Date: 2015-02-10
Classification: A61K

Abstract:
1. A remineralizing restorative composition for producing a mineralized dental tissue, the remineralizing restorative composition comprising: a calcium ion source and a hydroxide ion source, wherein the calcium ion source and the hydroxide ion source is a cement; a calcium phosphate-binding apatite stabilizer and a collagen-binding nucleation factor as a single biomimetic entity wherein the single biomimetic entity comprises poly(acrylic acid-co-vinyl phosphonic acid), poly(aspartic acid-co-vinyl phosphonic acid), poly(methacrylic acid-co-vinyl phosphonic acid), poly(acrylic acid-co-vinyl aminomethylene phosphonic acid), poly[acrylic acid-co-bis(2-chloroethyl)vinylphosphonate], poly[acrylic acid-co-1-hydroxyethylidene-1,1-diphosphonic acid] or poly[aspartic acid-co-bis(2-chloroethyl) vinylphosphonate; a phosphate ion source; and wherein the calcium ions are released over time for at least 30 days.