Patent ID: 7947452
Filing Date: 2011-05-24
Classification: A61K,A61P,C07K,C12N,C12Q

Abstract:
1. A method for implementing processes for detecting any strain of PTLV belonging to HTLV-1, HTLV-2, STLV-1, STLV-2, and STLV-3, said processes comprising: a) amplifying a target nucleic acid in a biological sample capable of containing PTLVs, with pairs of degenerate 5′ and 3′ oligonucleotides in the 5′ and 3′ orientation originating from the nucleotide sequences coding for the amino-terminal region of the surface component (SU) of the envelope proteins of the viruses of T lymphoma/leukemia in primates, said viruses collected together under the designation PTLV and being designated HTLV in human and STLV in monkey, wherein said amino-terminal region is a protein fragment delimited on the N-terminal side by an amino acid situated between positions 75 to 90 and on the C-terminal side by an amino acid situated between positions 130 to 145 of the envelope protein of the MT-2 strain of HTLV-1 represented by SEQ ID No: 43, or of the envelope protein of the NRA strain of RTLV-2 represented by SEQ ID NO: 45, or of the envelope protein of the strain of STLV-3 represented by SEQ ID NO: 47, or a virus carrying the sequences belonging to the SU of said PTLV, and b) identifying the strain of PTLV contained in the biological sample by determining the nucleotide fragments that have been amplified.