Patent ID: 6172207
Filing Date: 2001-01-09
Classification: C07B,C07H

Abstract:
A process for synthesizing labeled compounds with an isotopic element, comprising the steps of:preparing a labelling agent;labelling a precursor with the labelling agent, wherein the precursor is a protected substrate;pre-purifying the labelled precursor;retaining the labelled precursor on a solid support;deprotecting the labelled precursor, wherein deprotecting the labelled precursor converts the labelled precursor into a labelled compound in a deprotection step, wherein the labelled compound is free of the solid support; andformulating a final solution,wherein the deprotection step is performed directly on the solid support which is contained in a column or cartridge and wherein the labelled compound is 2-[.sup.18 F]fluoro-2-deoxy-D-glucose (FGD).