Patent ID: 7452858
Filing Date: 2008-11-18
Classification: A61K,A61P,Y10S

Abstract:
1. A method for treating gestational diabetes mellitus in a human in need thereof comprising subcutaneously injecting the human with about 1 microgram to about 50 micrograms per day of a peptide having the amino acid sequence of SEQ ID NO. 3, SEQ ID NO. 4, or SEQ ID NO. 5 to treat the gestational diabetes mellitus in the human in need thereof; wherein the peptide does not have the amino acid sequence of SEQ ID NO. 2; and wherein SEQ ID NO. 3 is: wherein: wherein SEQ ID NO. 4 is: wherein: provided that no more than three of Xaa 3 , Xaa 5 , Xaa 6 , Xaa 8 , Xaa 10 , Xaa 11 , Xaa 12 , Xaa 13 , Xaa 14 , Xaa 15 , Xaa 16 , Xaa 17 , Xaa 19 , Xaa 20 , Xaa 21 , Xaa 24 , Xaa 25 , Xaa 26 , Xaa 27 and Xaa 28 are Ala; and wherein SEQ ID NO. 5 is: wherein: provided that no more than three of Xaa 3 , Xaa 4 , Xaa 5 , Xaa 6 , Xaa 8 , Xaa 9 , Xaa 10 , Xaa 11 , Xaa 12 , Xaa 13 , Xaa 14 , Xaa 15 , Xaa 16 , Xaa 17 , Xaa 19 , Xaa 20 , Xaa 21 , Xaa 24 , Xaa 25 , Xaa 26 , Xaa 27 and Xaa 28 are Ala; and provided also that, if Xaa 1 is His, Arg, or Tyr, then at least one of Xaa 3 , Xaa 4 and Xaa 9 is Ala.