Patent ID: 6492107
Filing Date: 2002-12-10
Classification: C12N

Abstract:
A process for the production of a peptide, polypeptide, or protein having a predetermined property, comprising the steps of:producing stochastically generated polynucleotide sequences; forming a library of expression vectors comprising said stochastically generated polynucleotide sequences; culturing host cells comprising said library of expression vectors to produce said peptides, polypeptides, or proteins encoded by the stochastically generated polynucleotide. sequences; screening or selecting said host cells, to thereby identify a host cell comprising an expression vector encoding a peptide, polypeptide, or protein having the predetermined property; isolating a stochastically generated polynucleotide sequence from said expression vector which encodes the identified peptide, polypeptide, or protein; using the isolated stochastically generated polynucleotide sequence to produce the peptide, polypeptide, or protein having the predetermined property.