Patent ID: 6315854
Filing Date: 2001-11-13
Classification: A61F,A61K,Y10T

Abstract:
A process for the continuous production of transdermal therapeutic patches having a backing layer, a pressure-sensitive adhesive drug-reservoir-section and a removable protective layer, in which the loss of drug during fabrication is minimized, comprising the steps ofproviding a backing layer coated with a drug-free pressure-sensitive adhesive, wherein said backing layer is fed from a roll;and further providing a removable protective layer which is fed from a roll;placing individual quadrangular pressure-sensitive adhesive drug-reservoir sections lengthwise one after the other on said protective layer and covering the protective layer with said backing layer, and the clearance between said drug-reservoir sections in longitudinal direction remaining constant and the width thereof being dimensioned such that said backing layer and said removable protective layer project beyond said drug-reservoir-section at all sides thereof, whereafter the pressure-sensitive adhesive drug-free backing layer is cut by punching in such a manner that the punching line surrounds the external dimensions of the individual drug reservoir sections,removing the resulting latticed refuse of the drug-free pressure-sensitive adhesive backing layer, andthen cutting the protective layer in the resultant spaces between the drug-reservoir-sections.