Patent ID: 6048877
Filing Date: 2000-04-11
Classification: A61K,C07C,C07D

Abstract:
A method of treating cardiac arrhythmia which comprises administering to a mammal in need thereof an effective amount of a compound of the formula I ##STR266## where R.sup.1 is O-alkyl(aryl), CONH-alkyl, CONH-alkyl(aryl) or CONHalkyl(cycloalkyl)R.sup.2 is hydrogen;R.sup.3 is oxo, hydroxy, alkoxy, or NOH;R.sup.4 is hydrogen or alkyl;R.sup.5 is alkyl(heterocyclo) or alkyl(substituted amino); andn is an integer of 0 to 2with the proviso that where R.sup.3 is oxo, or hydroxy and R.sup.1 is phenylalkyloxy, then R.sup.5 is alkyl(heterocyclo).