Patent ID: 9089842
Filing Date: 2015-07-28
Classification: B01L,G01N

Abstract:
1. A method for bio-detection using a microfluidics chip having a liquid-metal (LM) interface and a substrate-metal (SM) interface, comprising: directing light at said microfluidics chip; measuring a first energy associated with photons of said light that interact with a first surface plasmon polariton (SPP) mode of said LM interface; measuring changes in said first energy; measuring a second energy associated with photons of said light that interact with a second SPP mode of said SM interface; measuring changes in said second energy; calibrating said changes in said first energy according to said changes in said second energy; and detecting, using said calibrated changes in said first energy, refractive index changes within said microfluidics chip, wherein said refractive index changes result from bio-receptor molecules within said microfluidics chip binding with analytes, wherein said microfluidics chip comprises a nanohole array.