Patent ID: 6800607
Filing Date: 2004-10-05
Classification: A61K,A61P,C07K

Abstract:
A modified brain-derived neurotrophic factor comprising:a first moiety of a brain-derived neurotrophic factor, from which a number average of 1 to 10 hydroxyl group(s) and/or hydrogen atom(s) have been removed from the carboxyl groups and/or amino groups of amino acids of the brain-derived neurotrophic factor, and a second moiety that is a 1-acyl-glycerol derivative selected from the group consisting of 1-acyl-glycero-3-phosphoryl choline, 1-acyl-glycero-3-phosphoryl serine and 1-acyl-glycero-3-phosphoryl ethylamine; wherein said first and second moieties are chemically cross-linked.