Patent ID: 8592210
Filing Date: 2013-11-26
Classification: A61K,C07K,C12N

Abstract:
1. A liposome for delivery of a target substance into cells, the liposome having one or more lipid bilayers, wherein each lipid bilayer comprises an inner and outer surface, wherein the inner and outer surface of each lipid bilayer consists of a single type of peptide, wherein the peptide consists of 7 to 10 consecutive arginine residues, wherein the peptide is modified with a hydrophobic group selected from the group consisting of saturated or unsaturated fatty acids capable of being inserted into said lipid bilayer consisting of noncationic lipids, wherein the hydrophobic group is inserted into each lipid bilayer so that the peptide is exposed on the inner and outer surface of the lipid bilayer, and wherein the amount of the modified peptide is 2% or more (molar ratio) of the total lipids making up each lipid bilayer.