Patent ID: 6090397
Filing Date: 2000-07-18
Classification: A61B,A61K,A61L

Abstract:
A kit of parts which comprises:(a) a first container comprising therein a polymerizable monomer or oligomer of a cyanoacrylate ester which, in monomeric form, is represented by formula I: ##STR4## wherein R is selected from the group consisting of: alkyl of 1 to 10 carbon atoms,alkenyl of 2 to 10 carbon atoms,cycloalkyl groups of from 5 to 8 carbon atoms,phenyl,2-ethoxyethyl,3-methoxybutyl,and a substituent of the formula: ##STR5## wherein each R' is independently selected from the group consisting of: hydrogen and methyl, andR"" is selected from the group consisting of:alkyl of from 1 to 6 carbon atoms,alkenyl of from 2 to 6 carbon atoms,alkynyl of from 2 to 6 carbon atoms,cycloalkyl of from 3 to 8 carbon atoms,aralkyl selected from the group consisting of benzyl, methylbenzyl and phenylethyl,phenyl, andphenyl substituted with 1 to 3 substituents selected from the group consisting of hydroxy, chloro, bromo, nitro, alkyl of 1 to 4 carbon atoms, and alkoxy of from 1 to 4 carbon atoms; and(b) a second container comprising therein an antimicrobially effective amount of a compatible antimicrobial agent which agent does not polymerize the cyanoacrylate ester within about 15 minutes of mixing with the cyanoacrylate ester,said containers being arranged for mixing the antimicrobial agent and the cyanoacrylate ester at the time of use to form an antimicrobial polymerizable cyanoacrylate composition.