Patent ID: 6207433
Filing Date: 2001-03-27
Classification: C12N

Abstract:
An isolated nucleic acid sequence encoding a polypeptide having 5-aminolevulinic acid synthase activity, selected from the group consisting of:(a) a nucleic acid sequence encoding a polypeptide having an amino acid sequence which has at least 90% identity with the amino acid sequence of SEQ ID NO. 2;(b) a nucleic acid sequence having at least 90% homology with the nucleic acid sequence of SEQ ID NO. 1;(c) a nucleic acid sequence which hybridizes under high stringency conditions with (i) the nucleic acid sequence of SEQ ID NO. 1 or (ii) its complementary strand; or a subsequence thereof of at least 100 nucleotides;(d) a subsequence of (a), (b), or (c), wherein the subsequence encodes a polypeptide fragment which has 5-aminolevulinic acid synthase activity.