Patent ID: 9149482
Filing Date: 2015-10-06
Classification: A61K,A61P

Abstract:
1. A chewable tablet comprising granules embedded in a matrix of excipients, wherein the granules consist of Cefixime having a mean particle size between 20μ and 120μ, mannitol, and magnesium stearate, and the matrix of excipients comprising hydroxypropyl cellulose, crospovidone, magnesium stearate, and one or more fruit flavoring agents, wherein the chewable tablet comprises, in addition to the Cefixime: 40-70 wt-% mannitol, 1-5 wt-% hydroxypropyl cellulose, 5-15 wt-% crospovidone; and 2-5 wt-% one or more fruit flavoring agents, wherein said chewable tablet has a property that makes the tablet chewable by patients who have difficulty in swallowing tablets, wherein said chewable tablet when chewed and swallowed by a human being, shows AUC and Cmax that are substantially equivalent to that of a suspension of Cefixime.