Patent ID: 6653140
Filing Date: 2003-11-25
Classification: G01N,Y10T

Abstract:
A method for assessing a patient's risk of having or developing coronary heart disease based on lipoprotein measurements, comprising:generating NMR spectra of a blood plasma or serum sample of a patient; measuring the values of a plurality of selected lipoprotein subclass constituents in the sample from NMR data; analyzing the measured values of the lipoprotein subclass constituents according to predetermined test criteria to identify whether there is an increased and/or decreased risk of having and/or developing coronary heart disease associated with the measured lipoprotein subclass constituent values; outputting the measured lipoprotein subclass values onto a report; providing a plurality of risk analysis portions, a respective one for each selected measured lipoprotein subclass value, each risk analysis portion depicting the identified risk for the corresponding measured lipoprotein subclass constituents value based on the predetermined test criteria analysis, to provide a contemporaneous risk assessment guide useful for interpretation of the risk associated with the measured value; automatically adjusting the predetermined risk criteria used to define whether a patient has an increased risk of having or developing coronary heart disease relative to the general population, for at least one selected lipoprotein subclass constituent when the patient has a known or diagnosed selected medical condition to thereby provide at least one reduced lipoprotein therapeutic target value for at-risk patients; and assigning an electronic identifier to a patient and electronically storing and comparing the measured lipoprotein subclass values of the patient over time in an automated manner, to monitor the impact of a drug therapy or treatment thereon.