Patent ID: 7868042
Filing Date: 2011-01-11
Classification: A23G,A23K,A61K,A61P,C07D,C07H,C11B

Abstract:
1. A method of treating or reducing the risk of kidney failure comprising administering to the subject in need thereof a composition comprising an effective amount of at least one compound having the formula A n , and/or a pharmaceutically acceptable salt thereof: wherein n is an integer from 2 to 18, such that there is at least one terminal monomeric unit A, and one or a plurality of additional monomeric units; R is 3-(α)-OH, 3-(β)-OH, 3-(α)-O-sugar, or 3-(β)-O-sugar; bonding between adjacent monomers takes place at positions selected from the group consisting of 4, 6 and 8; a bond of an additional monomeric unit in position 4 has alpha or beta stereochemistry; X, Y and Z are selected from the group consisting of monomeric unit A, hydrogen, and a sugar, with the proviso that as to the at least one terminal monomeric unit, bonding of the additional monomeric unit thereto is at position 4 and optionally Y═Z=hydrogen; the sugar is optionally substituted with a phenolic moiety; wherein the subject is a human or a veterinary animal.