Patent ID: 6706742
Filing Date: 2004-03-16
Classification: A61P,C07D,Y02P

Abstract:
A compound selected from those of formula (I): wherein: represents a 5-membered nitrogen-containing heterocycle optionally substituted by cyano,Ak represents a linear or branched (C1-C6)alkylene chain, X represents a single bond or phenylene, R1 and R2, which may be identical or different, each represent hydrogen or linear or branched (C1-C6)alkyl, Y represents NR4 or CHâ€”NO2, R4 represents hydrogen or linear or branched (C1-C6)alkyl, R3 represents: a group selected from linear or branched (C1-C6)alkyl, nitro and cyano, when Y represents CHâ€”NO2, or a group selected from nitro and cyano, when Y represents NR4, its tautomers when they exist, its optical isomers, and addition salts thereof with a pharmaceutically acceptable acid, with the exclusion of compounds wherein, simultaneously, represents an unsubstituted 5-membered nitrogen-containing heterocycle, Ak represents â€”(CH2)3â€”, X represents a single bond, Y represents NH and R3 represents nitro,it being understood that the term â€œ5-membered nitrogen-containing heterocycleâ€  is understood to mean a 5-membered saturated monocyclic group containing one, two or three hetero atoms, one of which hetero atoms is nitrogen, and any additional hetero atoms present are selected from oxygen, nitrogen and sulphur.