Patent ID: 6355640
Filing Date: 2002-03-12
Classification: A61P,C07D

Abstract:
A pyrazolopyridine compound of following formula: whereinR1 is aryl, and R2 is: cyclo(lower)alkyl or cyclo(lower)alkenyl, each of which may have 1 to 3 suitable substituent(s) selected from the group consisting of oxo, lower alkylenedioxy group, hydroxy, lower alkanoyloxy, tri(lower)alkylsilyloxy, hydroxy(lower)alkyl, lower alkanoyl, carboxy, protected carboxy, hydroxysulfonyl, lower alkyl, lower alkylidene, lower alkanoyl(lower)alkyl, carboxy(lower)alkyl, protected carboxy(lower)alkyl, lower alkanoyl(lower)alkylidene, carboxy(lower)alkylidene, protected carboxy(lower)alkylidene, cyano, cyano(lower)alkyl, cyano(lower)alkylidene, lower alkylidene substituted with unsaturated 3 to 8-membered heteromonocyclic group containing 1 to 4 nitrogen atom(s) which may have 1 to 4 lower alkyl, lower alkylidene substituted with unsaturated 3 to 8-membered heteromonocyclic group containing 1 to 2 oxygen atom(s) and 1 to 3 nitrogen atom(s) which may have 1 to 4 lower alkyl, hydroxyimino, lower alkoxyimino, lower alkanoyl(lower)alkoxyimino, carboxy(lower)alkoxyimino, protected carboxy(lower)alkoxyimino, hydroxysulfonyl(lower)alkoxyimino, lower alkanoyloxyimino, and hydroxysulfonyloxyimino; saturated 5 to 6-membered heterocyclic group containing a nitrogen or oxygen atom, which have oxo, and a suitable substituent selected from the group consisting of carboxy(lower)alkyl, lower alkoxycarbonyl(lower)alkyl and lower alkoxycarbonyl; 2,4-dioxo-1,2,3,4-tetrahydropyrimidin-6-yl, both nitrogen atoms of which have a suitable substituent selected from the group consisting of lower alkyl, carboxy(lower)alkyl and lower alkoxycarbonyl(lower)alkyl; or phenyl which may have lower alkoxy.