Patent ID: 7572825
Filing Date: 2009-08-11
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A method for the treatment of osteoporosis, rheumatoid arthritis, cancer associated bone disease, Paget's disease, or aseptic loosening of prosthetic implants, comprising administering to a subject in need of treatment a therapeutically-effective amount of a compound selected from compounds of the following formulae and pharmaceutically acceptable salts, amides, esters, and ethers thereof: wherein: Ar wherein: q is independently an integer from 0 to 4; r is independently an integer from 0 to 5; and each R R —OR —OR —O—R —O—C(═O)R —O—C(═O)OR —O—S(═O) wherein: each of R each of R Q is independently —OH or —OR wherein: —OR wherein: R C C wherein the group —C(═O)— in formula (1) is optionally replaced with a group selected from the following groups, wherein each R is independently C with the proviso that if —OR with the proviso that —OR