Patent ID: 8334311
Filing Date: 2012-12-18
Classification: A61K,A61P,C07D

Abstract:
1. A compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein R R R R R R R R R each R m is 0-4; m′ is 0-3; and each Y and Y′ is independently halo, OH, C1-C4 alkoxy, or C1-C8 alkyl, C2-C8 alkenyl, C2-C8 alkynyl, C6-C12 aryl, or C7-C14 arylalkyl, or a heteroform of one of these, each of which may be optionally substituted, wherein the term substituted is limited to the following substitutions: when present on an alkyl, alkenyl, alkynyl or a heteroform thereof, the substitution is halo, OH, ═O, ═N—CN, ═N—OR, ═NR, OR, NR when present on aryl or heteroaryl the substitution is halo, OH, OR, CH when present on an arylalkyl or heteroarylalkyl the substitution is as alkyl if on an alkyl or heteroalkyl portion, and is aryl if on an aryl or heteroaryl portion; wherein each of said heteroalkyl, heteroalkenyl, heteroalkynyl, heteroaryl, heteroarylalkyl and heterocyclyl, and heteroform contain one or two backbone heteroatoms selected from O, S and N and combinations thereof; and wherein cycloalkyl is a saturated or partially saturated, monocyclic or fused or spiro polycyclic, carbocycle that is connected via a ring carbon atom, cycloalkylalkyl is a carbocyclic non-aromatic group that is connected via an alkyl linker, heterocyclyl is a non-aromatic cyclic group that contains at least one heteroatom as a ring member and that is connected via a ring atom of the cyclic group, which may be C or N; and heterocyclylalkyl a heterocyclyl that is connected via an alkyl.