Patent ID: 8093428
Filing Date: 2012-01-10
Classification: C07C,C07D

Abstract:
1. A process for preparing a quaternary ammonium chloride salt compound of Formula (I): wherein A is carbonyl, thiocarbonyl or sulfonyl; X is a bond or —CH═CH—; R wherein aryl in R wherein C n is 0, 1, 2, 3 or 4; Y is a bond or —CH X R Z is —(CH R wherein aryl in R wherein C R comprising the steps: Step A. reacting a Compound A1 hydrochloride salt with an aldehyde or ketone Compound A2 to provide a Compound A3: Step B. reacting Compound A3 in the presence of a metallation reagent to provide a Compound A4: Step C. reacting Compound A4 with a Compound A5 (wherein Q represents a leaving group) to provide a Compound A6: Step D. reacting Compound A6 with a chlorinated alkyl Compound C1 to provide the Compound A9, representative of the Compound of Formula (I):