Patent ID: 6333305
Filing Date: 2001-12-25
Classification: A61K,A61P,C07K,C12N,C12P,C12R

Abstract:
The antibiotic TKR2999 having the physicochemical properties of (1), (2), (3), (4), and (5) described below and its pharmacologically acceptable salt:(1) the mass spectrum by FAB-MS method gives m/z 971 as [M+H].sup.+ ;(2) the molecular formula is represented by C.sub.44 H.sub.78 N.sub.10 O.sub.14, and its mass spectrum by high-resolution FAB-MS gives m/z 971.5776 as [M+H].sup.+ ;(3) the ultraviolet absorption spectrum in methanol has an end absorption;(4) the infrared absorption spectrum by KBr method shows the major absorption wave numbers at 3320, 2920, 1680, 1540, 1210, 1140, 840, 800, and 720 cm.sup.-1 ;(5) aspartic acid, threonine, serine, glycine, alanine, .beta.-alanine, and ornithine are detected by the amino acid analysis using ninhydrin reaction; and(6) the solubility is that it is soluble in methanol, and practically insoluble in hexane, chloroform, and water.