Patent ID: 6117883
Filing Date: 2000-09-12
Classification: A61P,C07D

Abstract:
A compound of formula I of the formula I: ##STR10## wherein R is selected from the group consisting of hydrogen, --CN, halogen, --CF.sub.3 and R.sup.4 ;R.sup.4 is selected from the group consisting of C.sub.1-16 -alkyl, C.sub.2-16 -alkenyl and C.sub.2-16 -alkynyl, each of which is optionally substituted with one or more independently selected from the group consisting of halogen(s), -CF.sub.3, and --CN;G is selected from one of the following azacyclic or azabicyclic ring systems: ##STR11## R.sup.1 and R.sup.2 independently are selected from the group consisting of hydrogen, C.sub.1-15 -alkyl, C.sub.2-5 -alkenyl, C.sub.2-5 -alkynyl, C.sub.1-10 -alkoxy, and C.sub.1-5 -alkyl substituted with one or more independently selected from the group consisting of --OH, --COR.sup.6', CH.sub.2 --OH, halogen, --NH.sub.2, carboxy, and phenyl;R.sup.6' is hydrogen, C.sub.1-6 -alkyl;R.sup.3 is selected from the group consisting of hydrogen, C.sub.1-5 -alkyl, C.sub.2-5 -alkenyl and C.sub.2-5 -alkynyl;n is 0, 1 or 2;m is 0, 1 or 2;p is 0, 1 or 2;q is 1 or 2;r is 0, 1 or 2;. . . . . . is a single or double bond.