Patent ID: 7405193
Filing Date: 2008-07-29
Classification: A61K,A61P,C07K

Abstract:
1. A method of accelerating skeletal muscle cell differentiation, comprising contacting skeletal muscle cells in vitro with gOBG3 polypeptides consisting of: amino acids 101-244 of SEQ ID NO: 6, amino acids 108-244 of SEQ ID NO: 6, amino acids 104-247 of SEQ ID NOs: 2 or 4, or amino acids 111-247 of SEQ ID NOs: 2 or 4, or variants thereof comprising polyethylene glycol conjugated to gOBG3 polypeptides consisting of: amino acids 101-244 of SEQ ID NO: 6, amino acids 108-244 of SEQ ID NO: 6, amino acids 104-247 of SEQ ID NOs: 2 or 4, or amino acids 111-247 of SEQ ID NOs: 2 or 4, wherein said gOBG3 accelerates the differentiation of said cells.