Patent ID: 6596734
Filing Date: 2003-07-22
Classification: C07D

Abstract:
A compound having the structure: wherein:each R1 is â€”NHS(O)mR, wherein R is alkyl, substituted alkyl, alkoxy, substituted alkoxy, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycle, or substituted heterocycle; each X is independently selected from the group consisting of halo, alkyl, substituted alkyl, alkoxy, substituted alkoxy, hydroxy, nitro, amino, and substituted amino; R2 is benzyl or benzyl substituted with one or more substitutes selected from the group consisting of halo, CF3, hydroxy, nitro, alkoxy, substituted alkoxy, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycle, substituted heterocycle, amino, and substituted amino of formula â€”NHRâ€² or â€”NRâ€²Râ€², wherein each Râ€² is alkyl, substituted alkyl, â€”C(O)Y, â€”C(O)NHY, or â€”C(O)SY, wherein Y is alkyl or substituted alkyl; R3 is H or alkyl; n is 0-3; m is 1-2; p is 1-4; the sum of n and p is 1-4; and pharmaceutically acceptable salts thereof.