Patent ID: 6162242
Filing Date: 2000-12-19
Classification: A61F,A61N

Abstract:
A method to selectively phototreat an abnormal intraocular blood vessel having an altered membrane without adversely affecting normal intraocular blood vessels comprisingadministering a photosensitizing agent susceptible to phototreatment into said normal and abnormal vessels,allowing a sufficient time for said agent to be released from said abnormal vessel through said altered membrane and into a site adjacent said abnormal vessel and maintaining said agent in said normal vessels,thereafter transiently constricting said normal vessels at a phototreatment site for displacing said agent from said normal vessels at said site and preserving said normal vessels during phototreatment,phototreating said site for a defined time during constriction of said normal vessels to selectively treat said abnormal vessel having said agent in said adjacent tissue, andthereafter restoring said normal vessels to an unconstricted state.