Patent ID: 8846341
Filing Date: 2014-09-30
Classification: C12Q,G01N

Abstract:
1. A method of identifying progression of idiopathic pulmonary fibrosis in a subject, comprising: measuring the serum or plasma levels of MMP7, DEFA-1, DEFA-2, DEFA-3, S100A12, and IL12P40 mRNA by use of a kit comprising a means for determining the serum or plasma levels of MMP7, DEFA-1 DEFA-2, DEFA-3, S100A12, and IL12P40 mRNA, wherein said kit does not contain means for determining the serum or plasma levels of more than twenty other markers, and wherein an increase in the level of MMP7 mRNA, an increase in the level of DEFA-1 mRNA, an increase in the level of DEFA-2 mRNA, an increase in the level of DEFA-3 mRNA, an increase in the level of S100A12 mRNA, and an increase in the level of IL12P40 mRNA indicate progression of idiopathic pulmonary fibrosis.