Patent ID: 7872155
Filing Date: 2011-01-18
Classification: C07C

Abstract:
1. A method for deprotecting an alkyl arylamine ether to produce a hydroxy arylamine compound, comprising: reacting an alkyl amine thiolate or an aryl amine thiolate reagent with an alkyl arylamine ether to yield a hydroxy arylamine compound, wherein the alkyl arylamine ether is represented by the following general formula: where Ar l , Ar 2 , Ar 3 , Ar 4 and Ar 5 each independently represents a substituted or unsubstituted aryl group, or Ar 5 independently represents a substituted or unsubstituted arylene group, and k represents 0 or 1, and at least one of Ar wherein the alkyl arylamine ether completely reacts in the presence of from about 1 to about 5 molar equivalents of the thiolate reagent during a reaction time of from about 30 minutes to about 12 hours.