Patent ID: 6277990
Filing Date: 2001-08-21
Classification: C07D

Abstract:
A compound of formula I: ##STR7##or a pharmaceutically acceptable base or acid addition salt, hydrate, cster, solvate, prodrug, metabolite, stereoisomer, or mixtures thereof, wherein:X is C.dbd.O;Q is NHCO;R.sub.1, R.sub.3, R.sub.4, R.sub.5, R.sub.7, R.sub.8, R.sub.9, R.sub.10, are, independently, hydrogen or lower alkyl;Y.sub.1 and Y.sub.2 are hydrogen;n is 0 to 10; andZ.sub.1 and Z.sub.2 are, independently: hydrogen, alkylhalo, alkylhydroxy, C.sub.1 -C.sub.10 straight or branched chain alkyl, C.sub.2 -C.sub.10 straight or branched chain alkenyl group, C.sub.2 -C.sub.10 straight or branched chain alkynyl group, aryl, benzyl, alkylamino, alkylcarboxy, alkylester, arylalkyl, or Z.sub.1 or Z.sub.2 taken together form a fused ring, wherein said ring has 4-8 ring members.