Patent ID: 6525093
Filing Date: 2003-02-25
Classification: A61P,C07C

Abstract:
A compound of the formula I: whereinstereocenters * are R or S; dotted lines indicate that a double bond may be present or absent, and the double bond geometry may be E or Z; R and Râ€² are independently H or C1-C20 linear or branched alkyl or alkenyl groups that may be substituted, or functional groups like COOR3, where R3=H or C1-C20 linear or branched alkyl or C5-C20 aryl; CONR1R2, where R1 and R2 may be independently or together H, linear or branched C1-C20 alkyl or C5-C20 aryl, NH2, OH, C1-C20 linear or branched alkoxy, halo, cyano, or R+Râ€²=O; A, Aâ€², Aâ€³, and C are independently H, C1-C20 acylamino, C1-C20 acyloxy, linear or branched C1-C20 alkanoyl, C1-C20 alkoxycarbonyl, C1-C20 linear or branched alkoxy; C1-C20 linear or branched alkylamino, C1-C20 alkylcarboxylamino, C1-C20 carbalkoxy; carboxyl, cyano, halo, hydroxy; and n, m, p and v are independently integers from 0 to 3; B, Bâ€² and Bâ€³ are independently H, C1-C20 acylamino, C1-C20 acyloxy; C1-C20 linear or branched alkanoyl, C1-C20 linear or branched alkenyl, C1-C20 alkoxycarbonyl, C1-C20 linear or branched alkoxy; C1-C20 linear or branched alkyl amino, C1-C20 alkyl carboxyl amino, C1-C20 carbalkoxy; aroyl, araalkanoyl, carboxyl, cyano, halo, hydroxy; and q, r and s are independently integers from 1 to 3; Râ€³, Râ€²â€³ and Râ€³â€³ are independently H, C1-C20 linear or branched alkyl or alkenyl groups which may contain substituents, COOH, C1-C20 alkoxycarbonyl, NH2, CONH2, C1-C20 acylamino, OH, C1-C20 alkoxy, halo, or cyano; X&boxH;NH, O, S, S&boxH;O, or SO2.