Patent ID: 8772286
Filing Date: 2014-07-08
Classification: A61K,A61P,C07D,Y02A

Abstract:
1. A compound of Formula I, or a pharmaceutically acceptable salt thereof, wherein A is CH or N; Y is a bond, or —C(O)NH—; X is a bond, —CH V is —CH W is a bond or —CH R1 is hydrogen or F; R2 is a (1-12C)heteroaryl or (6-10C)aryl both optionally substituted with one or more groups independently selected from R4; R3 is a hydrogen; (3-6C)cycloalkyl; (1-6C)alkyl, —(CH R4 is taken from halogen; OH; SH; nitrile, nitro, NH R5 is hydrogen (3-6C)cycloalkyl; or (1-6C)alkyl; R6 is hydrogen; (3-6C)cycloalkyl; (1-6C)alkyl; or (1-6C)alkylcarbonyl; R7 is hydrogen, (1-6C)alkyl or (3-6C)cycloalkyl; R8 is hydrogen; (3-6C)cycloalkyl; (1-6C)alkyl; or (1-6C)alkylcarbonyl; or R7 and R8 together with the nitrogen to which they are bonded in NR7R8 can form a 5-7-membered at least one nitrogen containing (4-6C)heterocyclyl ring which optionally contains one additional heteroatom selected from N, O or S; R9 is hydrogen; (1-6C)alkyl or (3-6)cycloalkyl; and m is 2 or 3.