Patent ID: 8133734
Filing Date: 2012-03-13
Classification: A61P,C07K,G01N,Y10S

Abstract:
1. A kit comprising (i) an isolated antibody or fragment thereof that binds specifically to an Interleukin 17 Receptor-Like Protein, wherein the Interleukin 17 Receptor-Like Protein consists of an amino acid sequence selected from the group consisting of: (a) the amino acid sequence from position −19 to position +407 of SEQ ID NO:2; (b) the amino acid sequence from position −18 to position +407 of SEQ ID NO:2; (c) the amino acid sequence from position +1 to position +407 of SEQ ID NO:2; (d) the amino acid sequence from position +1 to position +271 of SEQ ID NO:2; (e) the amino acid sequence from position −5 to position +271 of SEQ ID NO:2; (f) the amino acid sequence of the full length protein encoded by the cDNA in ATCC Deposit No. 209198; (g) the amino acid sequence of the full length protein, excluding the N-terminal methionine residue, encoded by the cDNA in ATCC Deposit No. 209198; and (h) the amino acid sequence of the extracellular domain of the protein encoded by the cDNA in ATCC Deposit No. 209198; and (ii) an isolated polypeptide comprising a portion of SEQ ID NO:2 or a portion of the protein encoded by the cDNA in ATCC Deposit No. 209198 which binds specifically with said isolated antibody or fragment thereof.