Patent ID: 6794371
Filing Date: 2004-09-21
Classification: A61K

Abstract:
A method for minimizing loss of bone mineral in mammals which method comprises administering to a mammal an amount of an aminoalkylenephosphonate or a pharmaceutically acceptable salt thereof which is effective to minimize loss of bone mineral density, wherein the aminoalkylenephosphonate is selected from the group consisting of 3,6,9,15-tetraazabicyclo[9.3.1]tetradeca-1(15),11,13-triene-3,6,9-trimethylenephosphonic acid (PCTMP), N,Nâ€²-bis(methylenephosphonic acid)-2,11-diaza[3.3](2,6)pyridinophane (BP2NO), and N,Nâ€²-bis(methylenephosphonic acid)-2-(aminomethyl)pyridine (AMPDMP).