Patent ID: 7718621
Filing Date: 2010-05-18
Classification: A61P,C07H

Abstract:
1. A compound of formula (I) wherein A is a bivalent radical —C(O)—, —N(R and R 1 is a group having the following formula: wherein R 13 is —OC(O)(CH 2 ) d U 1 R 14 , —OC(O)N(R 15 )(CH 2 ) d U 1 R 14 , —O(CH 2 ) d U 1 R 14 , or A is the bivalent radical —N(R wherein R 13 is —NHC(O)(CH 2 ) d U 1 R 14 ; R R R R R wherein V is a bivalent radical —CH 2 —, —CH(CN)—, —O—, —N(R 17 )— or —CH(SR 17 )—, with the proviso that when R 1 is a group of formula (IC), V is —O—; R R R R R R R wherein W is —C(R 41 )— and X is —C(R 41 )— or N, with the proviso that when X is —C(R 41 ) R 14 is linked at the 5-, 6-, 7-, or 8-position and when X is N, R 14 is linked at the 2-, 3-, or 4-position; R R R R R R R R R R R R R R R R R R R R U U Y and Z are each independently a bivalent radical —N(R d is an integer from 2 to 5; e is an integer from 2 to 4; f, i, k, m, n, p and q are each independently integers from 0 to 4; g, h, j and s are each independently integers from 0 to 2; r is an integer from 2 to 5; or a pharmaceutically acceptable salt thereof.