Patent ID: 8895258
Filing Date: 2014-11-25
Classification: G01N

Abstract:
1. A method of measuring a concentration of a specific protein using a biosensor comprising: feeding a sample comprising the specific protein into a biosensor; wherein the biosensor comprises a sample inlet through which the sample is drawn in, a working electrode on which a receptor layer is coated for selective binding to the specific protein in the drawn sample, and a measuring unit comprising a reference electrode to form a potential difference with the working electrode, applying a potential signal in a form of delta function waveform to the working electrode and the reference electrode; and measuring an impedance of the working electrode by Fourier-transforming an electric current obtained in response to the delta function waveform, wherein the specific protein is a glycated protein, and the receptor layer is formed as a self-assembled monolayer (SAM) which have boronic acid derivative as an end group.