Patent ID: 6616927
Filing Date: 2003-09-09
Classification: A61K,A61P,C07K,C12N,Y02A

Abstract:
A process for the production for immunoglobulin A (IgA) in the milk of a ruminant comprising:(a) actively immunizing a pregnant ruminant with an antigen by any two routes of administration selected from the group consisting of intra mammary (IMM) intra peritoneal (IP) and intramuscular (TM); and (b) actively immunizing said ruminant with an antigen by a third administration route selected from the group consisting of intra mammary (IMM), intra peritoneal (IP) and intramuscular (IM); with the proviso that all three administration routes are different; and wherein a higher IgA titre is produced as compared to an IgA titre produced by conducting step (a) alone.