Patent ID: 6146622
Filing Date: 2000-11-14
Classification: A61K,A61P,Y10S

Abstract:
A method of improving or enhancing the antimicrobial efficacy of a topically administrable pharmaceutical composition comprising a cationic antimicrobial, an anionic polyelectrolyte and an active ingredient, wherein the method comprises adding to the composition an antimicrobial-enhancing amount of an anionic amino acid based surfactant of the formula: ##STR4## wherein: R=C.sub.8 -C.sub.24 saturated or unsaturated hydrocarbon; Y=H, (CH.sub.2).sub.4 NH.sub.2 or (CH.sub.2).sub.3 NHC(NH.sub.2).dbd.N.sup.+ H.sub.2 ; andM.sup.+ =H or a pharmaceutically acceptable salt.