Patent ID: 9198871
Filing Date: 2015-12-01
Classification: A61K,C12Y

Abstract:
1. A process for the manufacture of pancreatin micropellets, comprising the steps of: a. providing pancreatin micropellet cores which comprises pancreatin and at least one pharmaceutically acceptable binding agent, wherein the binding agent is selected from the group consisting of: polyethylene glycol 2000, polyethylene glycol 3000, polyethylene glycol 4000, polyethylene glycol 6000, polyethylene glycol 8000 and polyethylene glycol 10000, wherein the pancreatin micropellet cores are substantially free of synthetic oils; b. providing an enteric coating solution comprising c. coating the pancreatin micropellet cores with the enteric coating solution wherein the temperature of the pancreatin micropellet cores during coating is kept at a temperature suitable to apply the enteric coating solution; and d. drying the enteric-coated pancreatin micropellet cores.