Patent ID: 7098003
Filing Date: 2006-08-29
Classification: A61K,C07K,C12N,C12P,C12Q,G01N,Y10S

Abstract:
1. An isolated nucleic acid encoding a polypeptide having at least 95% sequence identity to: (a) the amino acid sequence of the polypeptide of SEQ ID NO:522; (b) the amino acid sequence of the polypeptide of SEQ ID NO:522, lacking its associated signal peptide; (c) the amino acid sequence of the extracellular domain of the polypeptide of SEQ ID NO:522; (d) the amino acid sequence of the polypeptide encoded by the nucleic acid sequence of SEQ IDNO:521; (e) the amino acid sequence of the polypeptide encoded by the full-length coding sequence of the nucleic acid sequence of SEQ ID NO:521 or (f) the amino acid sequence of the polypeptide encoded by the full-length coding sequence of the cDNA deposited under ATCC accession number 203135; wherein said polypeptide induces chondrocyte re-differentiation.