Patent ID: 6124343
Filing Date: 2000-09-26
Classification: C07C,C07D

Abstract:
A compound of formula I: ##STR12## wherein R.sup.1 is CN, CH.sub.2 CN, CH.dbd.CHCN, CHO, or CH.dbd.CHCO.sub.2 H;R.sup.2 is heteroaryl lower alkoxy or heteroaryl lower alkylthio wherein each of the heteroaryl moieties is optionally substituted;R.sup.3 is halogen;R.sup.4 is optionally substituted alyl or optionally substituted heteroaryl;R.sup.5 is caboxy, sulpho, phosphono, alkylsulphonylcarbamoyl, tetrazolyl, arylsulphonylcarbamoyl, heteroarylsulphonylcarbamoyl or N-methoxycarbamoyl;X is oxygen or sulphur; andn is zero or 1;and wherein said heteroaryl is a thienyl ring; or an N-oxide thereof, solvate thereof or pharmaceutically acceptable salt thereof.