Patent ID: 9111740
Filing Date: 2015-08-18
Classification: H01J

Abstract:
1. A mass spectrometer comprising: an Electron Transfer Dissociation or Proton Transfer Reaction device comprising an ion guide comprising a plurality of electrodes; a first device arranged and adapted to drive or urge at least some first ions to pass through or along said ion guide, wherein said first device is arranged and adapted either: (i) to generate a linear axial DC electric field along at least a portion or along at least 1%, 5%, 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, 95% or 100% of an axial length of said ion guide; or (ii) to generate a non-linear or stepped axial DC electric field along at least a portion or along at least 1%, 5%, 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, 95% or 100% of the axial length of said ion guide; and a control system arranged and adapted to estimate, determine or measure a degree to which at least some first ions are fragmented or reduced in charge due to Electron Transfer Dissociation or Proton Transfer Reaction as said first ions are transmitted through said ion guide and in response thereto to vary, alter, increase or decrease one or more parameters which affect the transmission or degree of fragmentation or degree of charge reduction of said first ions as said first ions pass through said ion guide.