Patent ID: 6482584
Filing Date: 2002-11-19
Classification: A01N,A61L

Abstract:
An implant cleaning, perfusion and passivation process which comprises subjecting the entire implant to cyclic exposure of increased and decreased pressure above one atmosphere or below one atmosphere or both, wherein said implant consists essentially of autograft, allograft or xenograft tissue, or combinations thereof; said process comprisinga. evacuating a chamber containing said implant to a pressure that is sufficiently decreased such that internal channels present in the implant are primed for backfilling with cleaning solutions; b. backfilling said implant with a cleaning solution or a mixture of cleaning solutions; c. pressurizing said chamber; and d. cycling between steps (a) and (c) for between about 1-150 cycles, maintaining a temperature of between about 35-40 degrees centigrade, with optional application of ultrasonic energy.