Patent ID: 6641993
Filing Date: 2003-11-04
Classification: B01F,B01L,G01N,Y10S

Abstract:
In a method of mixing a plurality of liquids comprising the steps of:a) providing a probe tip with an internal cavity having a plurality of different inside diameters; b) providing by aspiration a plurality of liquids inside a portion of the probe tip; c) moving at least most of said liquids back and forth at least several times between a part of said cavity with a smaller inside diameter and a part with a larger inside diameter, said larger and smaller diameters being sufficient to provide a sufficient rotation of liquid as it moves between diameters to cause mixing of said liquids; the improvement wherein said cavity parts comprise two separate but matable tip portions, and said method further includes the step of mounting a mountable tip portion of one of said inside diameters onto said tip portion of the other inside diameter in-between aspiration of liquids, wherein said tip portion is removed after each additional liquid is aspirated, and a new tip portion is attached before aspirating into said probe tip an additional liquid such that carry-over contamination between liquids is prevented.