Patent ID: 6942966
Filing Date: 2005-09-13
Classification: A61P,B01J,C07D

Abstract:
1. A synthetic process comprising the steps of: providing a first chemical compound having a first functional group and a second functional group, said first chemical compound comprising a macrocyclic compound having a cyclic structure that is interrupted with at least one pyridine or triazine ring system, said pyridine or triazine ring system having two bridgehead atoms, each bridgehead atom being connected to at least one bridge containing at least three nitrogens, wherein each of said first functional group and said second functional group independently includes one of said three nitrogens; placing a blocking group on said first finctional group; reacting said second functional group with a first reagent pool comprising at least four different chemical compounds, thereby forming a first mixture of adducts having covalent bonds between said second functional group and said chemical compounds of said first reagent pool; deblocking said first functional group, thereby forming a first mixture of deblocked compounds; reacting at least a portion of said first mixture of deblocked compounds with a first reagent consisting essentially of a second chemical compound, thereby forming a mixture of products having covalent bonds between said first functional group and said second chemical compound.