Patent ID: 8741662
Filing Date: 2014-06-03
Classification: G01N

Abstract:
1. A method of diagnosing myocardial ischemia in a subject, comprising the steps of: (a) preparing an albumin enriched fraction from plasma or serum of the subject; (b) analyzing the albumin enriched fraction by size exclusion chromatograph (SEC) to produce SEC chromatograms of albumin-bound protein/peptide complexes (ABPPCs); and (c) comparing the SEC chromatograms of the ABPPCs from the subject to SEC chromatograms of ABPPCs from albumin enriched fraction from plasma or serum of a normal subject population wherein a reduction in height of at least one peak greater than or equal to about 66 kiloDaltons (kDa) in the subject is indicative of myocardial ischemia.