Patent ID: 6596261
Filing Date: 2003-07-22
Classification: A61K,A61P

Abstract:
A method to treating in a human or an animal a condition treated by oral or nasal inhalation, which comprises, administering an aerosol formulation comprising a medicament for the condition to said human or animal by oral or nasal inhalation, under conditions where the volume of distribution, Vc, is the maximum value; where Vc=DA+BKe=A+B(AÎ±+BÎ²),â€ƒ&agr;+&bgr;=K12+K21+Ke, andC=Aeâˆ’&agr;t+Beâˆ’&bgr;t where Ke is the rate constant of elimination of said medicament from the blood of said human or animal; K12 is the rate constant of transfer of said medicament from the blood of said human or animal to the rest of the body of said human or animal, K21 is the rate constant of the return of said medicament to the blood of said human or animal, &agr; and &bgr; are constants, C is the concentration of said medicament in the blood of said human or animal at any time, A is constant, B is constant and D is the dose of said administered medicament.