Patent ID: 8999340
Filing Date: 2015-04-07
Classification: A61K,A61P,C07K

Abstract:
1. A method for treating a patient afflicted with Degos' disease, the method comprising administering an antibody, or antigen-binding fragment thereof, that binds to a human complement component C5 protein, to a patient afflicted with Degos' disease, in an amount sufficient to treat the disease or lessen the severity of one or more symptoms of the disease, wherein the Degos' disease is multiorgan, systemic Degos' disease and wherein the one or more symptoms is selected from the group consisting of skin lesions, gastrointestinal bleeding, vomiting, enterocutaneous fistula, facial and acral paraesthesia, headaches, dizziness, aphagia, paraplegia, gaze palsy, epilepsy, memory loss, altered sensation, strokes, diplopia, ptosis, visual-field defects, weakness, shortness of breath, and chest pain.