Patent ID: 6448257
Filing Date: 2002-09-10
Classification: C07D

Abstract:
The compound of the formula: or having the structure of formula (A) or (B) wherein the positions on the benzo moiety of the tricyclic nucleus occupied by R3 and the substituent are reversed,wherein R2 is H, or is alkyl (1-6C) or aryl, each of said alkyl or aryl optionally including one heteroatom which is O, S or N, and optionally substituted by one or more substituents selected from the group consisting of halo, CN,&boxH;O, OR, SR, NR2, RCO, COOR, CONR2, OOCR, and NROCR where R is H or alkyl (1-6C), and wherein when R2 is alkyl said alkyl may be substituted by one or more substituents selected from the group consisting of piperazinyl, pyridinyl, piperidinyl and phenyl or wherein R2 is â€”(CO) O NR2 wherein n is an integer of 0-6 and R is H or alkyl (1-6C); R3 is H, halo, NO2, alkyl (1-6C), alkenyl (1-6C), alkynyl (1-6C), CN, OR, SR, NR2, RCO, COOR, CONR2, OOCR, or NROCR where R is H alkyl (1-6C); and each X4 is independently halo, alkyl (1-6C), OR, or NR2, wherein R is H or alkyl (1-6C) and p is 0, 1, 2 or 3.