Patent ID: 6288280
Filing Date: 2001-09-11
Classification: C07F

Abstract:
A process for the racemization of a compound of the formula I: ##STR7##which is present in the (R) form, the (S) form, or a non-racemic mixture of the (R) form and (S) form, whereinR.sup.1 is C.sub.1-8 -alkoxy, andR.sup.2 is hydrogen, C.sub.1-8 -alkyl, or C.sup.1-8 -alkoxy, orR.sup.1 and R.sup.2 taken together are methylenedioxy or ethylenedioxy;R.sup.3 is hydrogen, C.sub.1-8 -alkyl, or C.sub.1-8 -alkoxy; andR.sup.4 is phenyl or phenyl monosubstituted in the meta- or para-position by, C.sub.1-8 -alkyl, C.sup.1-8 -alkoxy, di- C.sub.1-8 -alkylamino, trialkylsilyl or phenyl;which comprises heating the compound of formula I to a temperature of from about 260.degree. C. to about 400.degree. C. for a time sufficient to cause racemization of the compound of formula I.