Patent ID: 6906224
Filing Date: 2005-06-14
Classification: C07B,C07C,C07D

Abstract:
1. A process for producing N-protected β-aminoalcohols of following formula (8), or a salt thereof: wherein A represents an unsubstituted or substituted alkyl group having 1 to 10 carbon atoms, aryl group having 6 to 15 carbon atoms or aralkyl group having 7 to 20 carbon atoms, an unsubstituted or substituted alkyl group having 1 to 10 carbon atoms which contains a hetero atom in the carbon skeleton, an aryl group having 6 to 15 carbon atoms which contains a hetero atom in the carbon skeleton, or an aralkyl group having 7 to 20 carbon atoms which contains a hetero atom in the carbon skeleton; B which comprises producing an N-protected α-aminohalomethyl ketone of formula (3), or a salt thereof, wherein A, B reacting a 3-oxazolidin-5-one derivative of the following (1): wherein R represents an unsubstituted or substituted aryl group or lower alkyl group, or a hydrogen atom, and A and B and then treating the reaction product with an acid.