Patent ID: 6432955
Filing Date: 2002-08-13
Classification: A61K,A61P,C07D,C07K

Abstract:
A GpIIb/IIIa antagonist of formula (L), wherein formula (L) isQ-[spacer]-COOHâ€ƒâ€ƒ(L) wherein Q is represented by formula wherein the substructure is a structure selected from whereinX is O or S; Xâ€² being independently CH or N; and m is 0, 1, 2 or 3; wherein the group Q is bound through an oxygen atom or an unsubstituted or substituted nitrogen or carbon atom;the distance between the amino substituted carbon atom of the group Q and the carbon atom of the carboxylate moiety has a length of 12-18 Ã¥; the spacer is any suitable chemical moiety; and the carboxylate group may be esterified.