Patent ID: 9108931
Filing Date: 2015-08-18
Classification: A61K,A61P,C07D,C07H,C07K

Abstract:
1. A compound of Formula I: wherein A is selected from the group consisting of aryl, heteroaryl, Trp, Tyr, Phe and His, where the aryl and heteroaryl groups are optionally substituted with 1 to 6 substituents independently selected from the group consisting of halo, OH, OC and where heteroaryl is an aromatic carbocyclic ring containing from 5 to 10 carbon atoms, in which 1 to 4 carbon atoms have been replaced with a heteroatom selected from one or more of O, S and N—R L R R * is the L or D configuration or mixtures thereof; m is 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49 or 50; n is 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49 or 50; and D is a functionally biologically active moiety selected from the group consisting of analgesics, opiates, antidotes, and synthetic vaccines, or a pharmaceutically acceptable salt, ester prodrug or amide prodrug thereof.