Patent ID: 7566775
Filing Date: 2009-07-28
Classification: C07H

Abstract:
1. A nucleic acid binding compound comprising a backbone, said backbone having attached heterocyclic groups wherein at least one of said heterocyclic groups has the formula I wherein X X X X if X if X if X if X X X if X if X if X if X R R R r and s are independently of each other an integer of from 1 to 18, D is the position of attachment of the group to the rest of the nucleic acid binding compound, said alkyl, alkenyl and alkynyl being unsubstituted or substituted by one or more moieties selected from the group consisting of -halogen, —SH, —S—(C —[O—(CH with the proviso that, if the heterocyclic group of the general formula I is 8-aza-7-deazaadenine (A*) which is attached to a 2′ Deoxy β-D erythropentofuranosyl moiety the sequence of said nucleic acid binding compound is not selected from the group consisting of (A*T) if the heterocyclic group of the general formula I is N if the heterocyclic group of the formula I is 8-aza-7-deazaadenine which is attached to a β-D-ribofuranosyl moiety the sequence of said compound contains at least one further heterocycle other than adenine and other than 8-aza-7-deazaadenine, if the heterocyclic group of the general formula I is 8-aza-9-deaza-9-methyl-guanin which is N if X