Patent ID: 6387413
Filing Date: 2002-05-14
Classification: A61L,C08B,C08L,Y10S

Abstract:
A gel comprising hyaluronic acid, or its alkali metal salt, said gel prepared by at least once freezing and subsequently thawing a hyaluronic acid aqueous solution at a pH of 3.5 or below, which has not been subjected to chemical crosslinking by a chemical crosslinking compound other than hyaluronic acid or chemical modification by a chemical modifying compound other than hyaluronic acid, and which is not in the form of a complex with a cationic polymer and (1) which dissolves in a neutral aqueous solution at 25Â° C. in one day to a degree of dissolution of at most 50%, or (2) which dissolves in a neutral aqueous solution at 37Â° C. in 12 hours to a degree of dissolution of at most 50%, or both (1) and (2).