Patent ID: 8865720
Filing Date: 2014-10-21
Classification: A61K,A61P,C07D,C12Q,G01N

Abstract:
1. A compound of formula (I), the N-oxide forms, the pharmaceutically acceptable addition salts and the stereo-chemically isomeric forms thereof, wherein n is 1; t is 0, and a direct bond is intended; each Q is each X is each Y is each Z is nitrogen; R R -L- is a direct bond or a bivalent radical selected from C each R R  is a radical selected from wherein each s is independently 0, 1, 2, 3, 4 or 5; each R the central  moiety may also be bridged (i.e. forming a bicyclic moiety) with a methylene, ethylene or propylene bridge; each R aryl in the above is phenyl, or phenyl substituted with one or more substituents each independently selected from halo, C