Patent ID: 6602294
Filing Date: 2003-08-05
Classification: A61B,A61F,A61K,A61L

Abstract:
An implantable substrate for the healing and/or protection of a connecting tissue, comprising:a composition comprising the biologically active factors (i), (ii), and (iii), wherein (i) is a growth and differentiating factor, (ii) is a chemotactic factor, and (iii) is a cellular adhesion molecule; and at least one structure for cell invasion in vivo and/or for the formation of cell matrix and/or for the release of constituents of the employed composition, wherein said structure comprises at least one constituent (a) to (f): (a) a hydrogel, (b) a compound selected from the group consisting of sponges, collagen sponges, (c) a compound selected from the group consisting of wool, a cotton wool-like structure, wool made of polysaccharides, cellulose wool, and cellulose cotton wool, (d) a compound selected from the group consisting of natural or synthetic polypeptides, fibrin, and polylysine, (e) a compound selected from the group consisting of plaitings, knitted fabrics, woolen structures made of fibers, and fibers comprising resorbable polymers, (f) a compound selected from the group consisting of cement pastes, acrylate cements, bonding sheets, and fibrinogen-covered hyaluronic acid foil.