Patent ID: 6645167
Filing Date: 2003-11-11
Classification: A61K,A61L,A61M,C08J

Abstract:
A method for embolizing a vascular site, comprising delivering, via a catheter, to said vascular site a composition comprising:(1) a biocompatible polymer; (2) a biocompatible water insoluble contrast agent; and (3) a biocompatible solvent, wherein said method comprises the following protocols, conducted during a single surgical procedure: (a) positioning the distal end of said delivery catheter in said vascular site, wherein said delivery catheter is connected to a source of said composition and whereby said composition can be injected into the vascular site through said delivery catheter; (b) positioning a flow-arresting device at said vascular site to be embolized; (c) activating the flow-arresting device at said vascular site to be embolized such that the activated device substantially arrests blood flow through said vascular site; (d) injecting said composition into said vascular site; (e) partially deactivating said flow-arresting device until is has a diameter of from about 10% to about 90% of said inner diameter of said vascular site to permit sufficient blood flow through said vascular site to be embolized, such that removal of said biocompatible solvent is facilitated and oxygenated blood is delivered to the tissue distal to said flow-arresting device; and (f) repeating protocols (c)-(e) at least once, and as necessary, to effect embolization of said vascular site.