Patent ID: 8932837
Filing Date: 2015-01-13
Classification: C12N,C12P

Abstract:
1. A process for producing optically active 3-aminocarboxylic acid ester compounds of general Formula I, and the ammonium salts thereof, wherein R R in which an enantiomeric mixture of a simply N-acylated 3-aminocarboxylic acid ester of general formula (I.b), in which R 1 and R 2 have the meanings given above and R 3 stands for hydrogen, alkyl, cycloalkyl or aryl, is submitted to an enantioselective deacylation by adding a polypeptide with amidase activity selected from the group consisting of: a) a polypeptide comprising the amino acid sequence according to SEQ ID NO: 2; and b) a polypeptide comprising an amino acid sequence that has at least 96% sequence identity with SEQ ID NO: 2.