Patent ID: 6541469
Filing Date: 2003-04-01
Classification: A61P,C07D

Abstract:
A compound having the following structure: or a stereoisomer or pharmaceutically acceptable salt thereof,wherein: X is nitrogen or CR3; A is O, S or NR4; â€œâ€”â€”â€”â€  represents an optional double bond; R is an optional substituent which, at each occurrence, is independently alkyl, aryl, heteroaryl, alkylidenyl, arylalkyl or heteroarylalkyl, wherein m is 0, 1, 2 or 3 and represents the number of R substituents; wherein, when R is a monovalent substituent, it is single-bonded to the ring, and when R is a divalent substituent, it is double-bonded to the ring. R1 is alkyl substituted alkyl, aryl, substituted aryl, heteroaryl or substituted heteroaryl; R2 is hydrogen, halogen, cyano, alkyl, substituted alkyl, alkoxy or thioalkyl; R3 is hydrogen, halogen, alkyl or substituted alkyl; and R4 is hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, heterocycle or substituted heterocycle.