Patent ID: 6270971
Filing Date: 2001-08-07
Classification: C12Q

Abstract:
A method for detecting a chromosomal aberration in a human patient, comprising:(a) obtaining a composition comprising detectably-labeled chromosome-specific paints prepared from chromosomes or chromosome fragments of at least two different nonhuman animal species; wherein said detectably-labeled chromosome-specific paints are detectably labeled with at least two different labels;(b) hybridizing the paints of the composition to one or more chromosomes of the human patient, thereby producing a banding pattern;(c) detecting the banding pattern resulting from the hybridization;(d) comparing the banding pattern detected to a banding pattern characteristic of normal human chromosomes hybridized with said paints, and(e) detecting a difference between the banding pattern detected in (c) and the banding pattern characteristic of normal human chromosomes, wherein a difference is indicative of a chromosomal aberration in the human patient.