Patent ID: 6506906
Filing Date: 2003-01-14
Classification: A61K,C07D,C07K,C08G,C12Q

Abstract:
A polyamide of the formula or a pharmaceutically acceptable salt thereof, wherein:n is 5-11; m is 0-6; each Y is independently selected from the group consisting of whereinp is 0 to 5, provided that at least one Y is not â€”NH-; Z is a covalent bond or whereinr is 1-3; each X is independently selected from the group consisting C and N; each R1 is independently selected from the group consisting of H, C1-6 alkylamine, C1-6 alkyldiamine, C1-6 alkylcarboxylate, C1-6 alkyl, C1-6 alkenyl, C1-6 alkynyl and C1-6 alkyl-L; each R2 independently selected from the group consisting of H and OH if X is C, and is not present if X is N; R3 is selected from the group consisting of H, Cl, NO, N-acetyl, benzyl, C1-6 alkyl, C1-6 alkenyl, and C1-6 alkynyl; and R4 is â€”NR5R6 or â€”NH(CH2)0-6NR5R6, where R5 and R6 are independently chosen from the group consisting of H, Cl, NO, N-acetyl, benzyl, C1-6 alkyl, C1-6 alkylamine, C1-6 alkyldiamine, C1-6 alkylcarboxylate, C1-6 alkenyl, C1-6 alkyl, and C1-6 alkyl-L; wherein L is a detectable label, and wherein at least one R1, R5, of R6 is C1-6 alkyl-L.