Patent ID: 7279468
Filing Date: 2007-10-09
Classification: A61K,A61P

Abstract:
1. A compound of the formula I and the physiologically tolerable salts, and the enantiomerically pure or diastereomerically pure and tautomeric forms thereof, where R independently of one another are hydrogen, a branched or unbranched, optionally substituted C where said fused, unsaturated or aromatic 3- to 10-membered carbocycle or heterocycle is optionally substituted by, independently of one another up to four substituents from the group consisting of hydroxyl, halogen or a branched or unbranched, optionally halogen-substituted C A is a structural element selected from the group of structural elements of the formulae I where m,p and q independently of one another are 1, 2 or 3, R independently of one another are hydrogen, CN, halogen, a branched or unbranched, optionally substituted C R independently of one another are hydrogen, CN, halogen, a branched or unbranched, optionally substituted C where R independently of one another are hydrogen, a branched or unbranched, optionally substituted C R independently of one another are hydrogen, —(CH where n is 1, j is 0 or 1, X R R independently of one another are hydrogen, a branched or unbranched, optionally substituted C R are hydrogen, a branched or unbranched, optionally substituted C R R R independently of one another are hydrogen, —CN, halogen, a branched or unbranched, optionally substituted C R R R independently of one another are hydrogen, a branched or unbranched, optionally substituted C Z independently of one another are nitrogen, C—H, C-halogen or a branched or unbranched, optionally substituted C—C Z and wherein for each of the radicals the optional substituents are independently selected from the group consisting of —NO and E is composed of two to four substructural elements, selected from the group E E E where c is 1, d, f, g and h independently of one another are 0, 1 or 2, k2, k3, k4, k5 and k6 independently of one another are 0 or 1, X independently of one another are an optionally substituted 4- to 11-membered mono- or polycyclic, aliphatic or aromatic hydrocarbon which can contain up to 6 double bonds and up to 6 identical or different heteroatoms selected from the group N, O and S, where the ring carbons and/or the ring nitrogens can optionally be substituted, Z is CO, CO—NR independently of one another are hydrogen, halogen, a hydroxyl group, a branched or unbranched, optionally substituted C x is 0, 1, 2, 3 or 4, z is 0 or 1, W R independently of one another are hydrogen, a branched or unbranched, optionally substituted C R R independently of one another are hydrogen, a branched or unbranched, optionally substituted C R R independently of one another are hydrogen, a hydroxyl group, a branched or unbranched, optionally substituted C R R and wherein for each of the radicals the optional substituents are independently selected from the group consisting of —NO