Patent ID: 6552054
Filing Date: 2003-04-22
Classification: A61P,C07D

Abstract:
A compound of the formula: wherein the ring A is an optionally substituted benzene ring which may be substituted by 1 to 3 substituents selected from the group consisting of hydroxy, acyloxy, mercapto, halogen atom, C1-10 alkyl, C1-10 alkoxy, C1-10 alkylthio and alkylenedioxy of the formula: â€”Oâ€”(CH2)mâ€”Oâ€”, wherein m is an integer of 1-4; R1 is an optionally substituted non-aromatic heterocyclic group, wherein said non-aromatic heterocyclic group is a 5- to 7-membered non-aromatic heterocyclic group containing from 1 to 4 heteroatoms selected from the group consisting of nitrogen atom, sulfur atom and oxygen atom, and wherein optional substituents of said non-aromatic heterocyclic group are 1 to 4 substituents selected from the group consisting of halogen atom, hydroxy, oxo, C1-10 alkyl, C10-6 alkoxy, C1-6 acyl, amino, mono- or di-C1-6 alkylamino, C1-6 alkylsulfonyl, carboxy, C1-6 alkoxy-carbonyl and phosphono; R2 is a hydrogen atom or a hydrocarbon group; R3 is a hydrogen atom, a hydrocarbon group or halogen; n is an integer of 0 to 3; or a salt thereof;or a prodrug thereof.