Patent ID: 9199023
Filing Date: 2015-12-01
Classification: A61M,B01D

Abstract:
1. An oxygenator, comprising: a housing; a hollow fiber membrane layer that is stored in the housing and possesses multiple integrated hollow fiber membranes with a gas exchange function; a gas inlet portion and a gas outlet portion that are provided on the upstream and downstream of gas passages in lumens of the hollow fiber membranes, respectively; a blood inlet portion and a blood outlet portion that are provided on the upstream and downstream of blood passages outsides of the hollow fiber membranes, respectively; wherein the hollow fiber membranes in the hollow fiber membrane layer each possess first and second end portions, and are fixed to each other at the first end portions and the second end portions; and wherein condition (a) 30 ≦ε≦60 and condition (b) OD≦4.5×ε are met where ε [μm] is an average separation distance between the adjacent hollow fiber membranes at a fixed portion of the hollow fiber membrane layer and OD [μm] is the outer diameter of the hollow fiber membranes, and condition (c) L≦1.3×ID is met where ID [μm] is the inner diameter of the hollow fiber membranes and L [mm] is the length of the hollow fiber membranes contributing to gas exchange, such that, when conditions 120 ≦OD ≦220, (a), (b) and (c) are met and blood is introduced into the housing, the ratio of blood in the housing to membrane surface area in contact with the blood is in the range of 25 to 50 mL/m