Patent ID: 7244751
Filing Date: 2007-07-17
Classification: A61P,C07C,C07D

Abstract:
1. A compound of formula I: or its stereoisomer, enantiomer, diastereomer, or a pharmaceutically acceptable salt; wherein A is a phenyl or pyridyl, optionally substituted with 1 to 4 substituents selected from the group consisting of a halogen atom, an alkyl group having 1 to 4 carbons, and a perfluoralkyl group having 1 to 4 carbons; B is-phenyl; Z is a bond; Y is a moiety having —CO— which is linear and in which the distances between the centroid of ring B (W1), the centroid of ring A (W2) and an oxygen atom as a hydrogen bond acceptor in the moiety Y (W3) are: W1-W2=about 6.0 to about 12.0 Å, W1-W3=about 3.0 to about 6.0 Å, and W2−W3=about 4.0 to about 8.0 Å, respectively; R R R One of X