Patent ID: 6409664
Filing Date: 2002-06-25
Classification: C12Q,G06G

Abstract:
An apparatus for predicting a quantitative probability of disease recurrence in a patient with prostatic cancer following an identified therapy, wherein the apparatus comprises:a correlation of factors determined for each of a plurality of persons previously diagnosed with prostatic cancer and having been treated by said identified therapy with incidence of recurrence of prostatic cancer for each person of said plurality of persons, wherein said selected set of factors comprises two or more factors selected from the group consisting of pretreatment PSA level, combined Gleason grade, specimen Gleason sum, clinical stage, surgical margin status, prostatic capsular invasion maximum cancer length in a core, total length of cancer in the biopsy cores, percent of cores positive level, extraprostatic extension, level of extraprostatic extension, apoptotic index, percent of cancer in one or more cores, percent of high grade cancer in one or more cores, total tumor volume, zone of location of the cancer, presence of seminal vesicle invasion, type of seminal vesicle invasion, p53, Ki-67, p27, DNA ploidy status, lymph node status, and lymphovascular invasion; and a processor, wherein said processor compares an identical set of factors determined from the patient diagnosed as having prostatic cancer to the correlation to predict the quantitative probability of recurrence of prostatic cancer in the patient following said identified therapy.