Patent ID: 9078636
Filing Date: 2015-07-14
Classification: A61B

Abstract:
1. A method of treating tissue to enhance the effects of ablation comprising: identifying tissue to receive ablation therapy; treating the tissue with a temperature-sensitizing agent; and activating an ablation therapy device proximate the treated tissue, the temperature-sensitizing agent being a temperature-sensitizing adjuvant selected from the group consisting of: thermophysical adjuvants, chemotherapeutic adjuvants, vascular adjuvants, immunomodulator adjuvants, and combinations thereof, and the temperature-sensitizing agent being applied to the tissue by an applicator that is integrated with the ablation therapy device, the applicator being an ablation element having an outer surface that is coated with a layer of temperature-sensitizing adjuvant and a layer of temperature-sensitive substrate material between the ablation element and the layer of temperature-sensitizing adjuvant, the layer of substrate material readily separating from the ablation element when substrate material is within a certain temperature range; the ablation therapy being at least one of: