Patent ID: 6586571
Filing Date: 2003-07-01
Classification: A61K,A61P,C07K,C12N

Abstract:
An isolated polypeptide that binds to MORT-1 protein, said polypeptide having a sequence comprising:(a) residues 1-182 of SEQ ID NO:5; (b) an analog of (a), differing therefrom by no more than ten changes in the amino acid sequence thereof, each said change being a substitution, deletion and/or insertion of a single amino acid, which analog binds to MORT-1 protein; (c) a fragment of (a) or (b), which fragment binds to MORT-1 protein; or (d) a derivative of (a), (b) or (c) by modification of a functional group which occurs as a side chain or an N- or C-terminal group of one or more amino acid residues thereof without changing one amino acid to another of the twenty commonly occurring natural amino acids, which derivative binds to MORT-1 protein.