Patent ID: 7364730
Filing Date: 2008-04-29
Classification: A61K,A61P,C07K,C12N

Abstract:
1. A method of prognosing cancer in a mammal, comprising assessing the quantitative presence of a polypeptide having the function of the human K + eag ion channel and encoded by a nucleic acid sequence selected from the group consisting of: (a) a nucleic acid sequence encoding the polypeptide having the amino acid sequence SEQ ID NO:3; (b) a nucleic acid sequence that hybridizes to the complementary strand of the nucleic acid sequence of (a) at 4×SSC at 65° C. or at 4×SSC at 42° C. in 50% formamide, followed by washing in 0.1×SSC at 65° C. for one hour; and (c) a nucleic acid sequence that is degenerate to the nucleic acid sequence of (b); in cells of the mammal to be tested, wherein the presence of the polypeptide in the cells compared to normal cells indicates cancer.