Patent ID: 7838529
Filing Date: 2010-11-23
Classification: A61P,C07D

Abstract:
1. A compound of formula (I) wherein: R R an aryl-D-C a C a C R a C a C R a piperidin-1-yl or hexahydroazepin-1-yl group which is substituted in the 3 position or 4 position by an amino, C a 3-aminopiperidin-1-yl group wherein the piperidin-1-yl moiety is optionally additionally substituted by an aminocarbonyl, C a 3-aminopiperidin-1-yl group wherein the piperidin-1-yl moiety is additionally substituted in the 4 position or 5 position by a hydroxy or methoxy group, a 3-aminopiperidin- 1-yl group wherein the methylene group in the 2 position or 6 position is replaced by a carbonyl group, a piperidin-1-yl or hexahydroazepin-1-yl group substituted in the 3 position by an amino, C an azetidin-1-yl, pyrrolidin-1-yl, piperidin-1-yl, or hexahydroazepin-1-yl group substituted by an amino-C a piperazin-1-yl or [1,4]diazepan-1-yl group optionally substituted on the carbon skeleton by one or two C a 3-iminopiperazin- 1 -yl, 3-imino-[1,4]diazepan- 1 -yl, or 5-imino-[1,4]diazepan- 1-yl group optionally substituted on the carbon skeleton by one or two C a [1,4]diazepan-1-yl group optionally substituted by one or two C a C a C a C a C a C an N—(C a C an N—(C a C an N—(C a C an N—(C an R an R an amino group substituted by R an amino group substituted by R an R a 3-amino-2-oxopiperidin-5-yl or 3-amino-2-oxo-1-methylpiperidin-5-yl group, a pyrrolidin-3-yl, piperidin-3-yl, piperidin-4-yl, hexahydroazepin-3-yl, or hexahydroazepin-4-yl group substituted in the 1 position by an amino, C an azetidin-2-yl-C R R wherein: R or a prodrug or salt thereof.