Patent ID: 6143252
Filing Date: 2000-11-07
Classification: B01J,B01L,C40B,G01N

Abstract:
A pipetting device for solid phase synthesis, said device comprisinga cylinder having an upper end and a lower end and defining a cylindrical chamber extending therebetween,a plunger having an upper end and a lower end, wherein the plunger (i) is slidably movable in the cylindrical chamber between a retracted and an inserted position, (ii) has an outer diameter that is less than the inner diameter of the chamber, and wherein the difference between the outer diameter of the plunger and the inner diameter of the cylindrical chamber is large enough to allow fluid passage and (iii) has a central passageway leading from a portion of the plunger above said chamber to an egress port which traverses a lateral wall of the plunger within said chamber,a seal disposed adjacent the upper end of said cylinder for holding said plunger during movement thereof, anda pipetting terminus for mounting a disposable pipette tip, wherein said plunger is movable between (i) a retracted position wherein said egress port is positioned above said chamber, and (ii) an inserted position wherein said egress port is positioned within said chamber, for introducing a fluid through said passageway into the cylindrical chamber for delivery to a pipette tip when a pipette tip is mounted on said pipetting terminus.