Patent ID: 8912330
Filing Date: 2014-12-16
Classification: A61K,A61P,C07D

Abstract:
1. A compound, tautomer or pharmaceutically acceptable salt of Formula 1: wherein Ring A is selected from: Ring B is a 5-membered heteroaryl ring comprising carbon atoms and 1 to 3 nitrogen atoms; L X is O or NR Ring C is an aryl, a 3- to 8-membered carbocyclyl or a 5-, 6- or 7- membered heterocyclic or heteroaryl ring comprising carbon atoms and 1-4 heteroatoms independently selected from O, N, P(O) and S(O) Ring D is an aryl or a 5- or 6-membered heteroaryl ring comprising carbon atoms and 1 to 4 heteroatoms independently selected from O, N and S; R R or alternatively two adjacent R r is 0, 1 or 2; n is 0, 1 or 2; p is 0, 1,2,3,4 or 5; s is 0, 1,2,3,4 or 5; each occurrence of Y is independently a bond, —O —, —S— or —NR each occurrence of R each occurrence of R R alternatively, each NR each of the foregoing alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, cycloalkynyl, aryl, heteroaryl and heterocyclic moiety is optionally substituted.