Patent ID: 6579893
Filing Date: 2003-06-17
Classification: A61K,A61L,A61P,G10K

Abstract:
A method for treating a subject having a mesenchymal tumor, which tumor is sensitive to a compound of Formula I, comprising administering to the subject a therapeutically effective amount of a compound of Formula I or a pharmaceutically acceptable salt of a compound of Formula I, wherein Formula I is: wherein R1 and R2 are the same or different and each represents a hydrogen atom or a C1-C5 alkyl group;R3 represents a hydrogen atom, a C1-C6 aliphatic acyl group, an alicyclic acyl group, an aromatic acyl group, a heterocyclic acyl group, an araliphatic acyl group, a (C1-C6 alkoxy)carbonyl group, or an aralyloxycarbonyl group; R4 and R5 are the same or different and each represents a hydrogen atom, a C1-C5 alkyl group or a C1-C5 alkoxy group, or R4 and R5 together represent a C1-C4 alkylenedioxy group; n is 1, 2 or 3; W represents the â€”CH2â€”, >CO, or CHâ€”OR6 group in which R6 represents any one of the atoms or groups defined for R3 and may be the same as or different from R3); and Y and Z are the same or different and each represents an oxygen atom or an imino (=NH) group.