Patent ID: 8057798
Filing Date: 2011-11-15
Classification: A61K,A61P,B82Y,C07K,C12N

Abstract:
1. A complex comprising an anti-Dendritic Cell Immunoreceptor (DCIR) immunoglobulin or DCIR-binding portion thereof, a cohesin/dockerin binding pair, and an antigen, wherein the immunoglobulin or DCIR-binding portion thereof is bound to one half of a cohesin/dockerin binding pair at a site other than the DCIR binding portion and the antigen is bound to the complementary half of the cohesin/dockerin binding pair, such that the antigen forms a complex with the immunoglobulin or DCIR-binding portion thereof, wherein the immunoglobulin or DCIR binding portion thereof and the antigen are internalized by an antigen presenting cell that has been contacted with the antibody-antigen complex and the antigen is presented by the antigen presenting cell.