Patent ID: 8295927
Filing Date: 2012-10-23
Classification: A61B,A61N

Abstract:
1. A machine-assisted method comprising: measuring a first impedance, during at least a portion of a cardiac cycle, between a first electrode associated with a first ventricle of a heart and a reference electrode; measuring a second impedance, during at least the portion of the cardiac cycle, between a second electrode associated with a second ventricle of the heart, in which the second ventricle is different from the first ventricle, and the same or a different reference electrode; measuring a phase difference between the first and second impedances; and automatically adjusting in a closed loop manner, using the measured phase difference as an error signal, a cardiac resynchronization therapy parameter that synchronizes left and right ventricular heart contractions, the automatically adjusting tending to reduce the phase difference during a subsequent cardiac cycle, wherein the automatically adjusting comprises: