Patent ID: 8143325
Filing Date: 2012-03-27
Classification: A61K,A61L,A61P,C08G,C09J

Abstract:
1. A compound selected from the group consisting of: wherein each X represents a member independently selected from the group consisting of: —CH 2 COO— (glycolic acid moiety); —CH(CH 3 )COO— (lactic acid moiety); —CH 2 CH 2 OCH 2 COO— (dioxanone moiety); —CH 2 CH 2 CH 2 CH 2 CH 2 COO— (caprolactone moiety); —(CH 2 ) y COO— where y is one of the numbers 2,3,4 and 6-24 inclusive; and —(CH 2 CH 2 O) z′ CH 2 COO— where z′ is an integer between 2 and 24, inclusive; each X′ represents a member independently selected from the group consisting of: —OOCCH 2 — (glycolic acid moiety); —OOC(CH 3 )CH— (lactic acid moiety); —OOCCH 2 OCH 2 CH 2 — (dioxanone moiety); —OOCCH 2 CH 2 CH 2 CH 2 CH 2 — (caprolactone moiety); —OOC(CH 2 )y- where y is one of the numbers 2,3,4 and 6-24 inclusive; and —OOCCH 2 (OCH 2 CH 2 )z′- where z′ is an integer between 2 and 24, inclusive; each X″ represents a member independently selected from the group consisting of: —OCH 2 CO— (glycolic acid moiety); —OCH(CH 3 )CO— (lactic acid moiety); —OCH 2 CH 2 OCH 2 CO— (dioxanone moiety); —OCH 2 CH 2 CH 2 CH 2 CH 2 CO— (caprolactone moiety); —O(CH 2 ) y CO— where y is one of the numbers 2,3,4 and 6-24 inclusive; and —O(CH 2 CH 2 O) z′ CH 2 CO— where z′ is an integer between 2 and 24, inclusive; each Y represents a member independently selected from the group consisting of: —COCH 2 O— (glycolic ester moiety); —COCH(CH 3 )O— (lactic ester moiety); —COCH 2 OCH 2 CH 2 O— (dioxanone ester moiety); —COCH 2 CH 2 CH 2 CH 2 CH 2 O— (caprolactone ester moiety); —CO(CH 2 ) m O— where m is an integer between 2-4 and 6-24 inclusive; and —COCH 2 O(CH 2 CH 2 O) n — where n is an integer between 2 and 24, inclusive; each Y′ represents a member independently selected from the group consisting of: —OCH 2 OC— (glycolic ester moiety); —O(CH3)CHOC— (lactic ester moiety); —OCH 2 CH 2 OCH 2 OC— (dioxanone ester moiety); —OCH 2 CH 2 CH 2 CH 2 CH 2 OC— (caprolactone ester moiety); —O(CH 2 )mOC— where m is an integer between 2-4 and 6-24 inclusive; and —(OCH 2 CH 2 )nOCH 2 OC— where n is an integer between 2 and 24 inclusive; each R is a benzyl or an alkyl group, the alkyl group being straight-chained or branched; each p is independently an integer between 1 and 4, inclusive; Z is O or NH; and Rn represents one or more members selected from the group consisting of H, alkoxy, benzyloxy, aldehyde, halogen, carboxylic acid and —NO 2 , which is attached directly to an aromatic ring or attached through an aliphatic chain.