Patent ID: 7037912
Filing Date: 2006-05-02
Classification: A61P,C07C,C07D,C07F

Abstract:
1. A compound of formula II: or a pharmaceutically acceptable salt thereof wherein: one L is selected from the group consisting of: (a) a moiety of formula XI: wherein each R R each R Q Q each m is independently an integer from 1 to 3; (b) a moiety of formula XII: wherein each R R R E is CH or N; and (c) a moiety of formula XIII: wherein each R R D is a covalent bond, NR E is CH or N; and the other L is selected from the group consisting of: (d) a moiety of formula XI; (e) a moiety of formula XII; (f) a moiety of formula XIII: (g) a moiety of formula VI: wherein each R R each Q provided one and only one of R (h) a moiety of formula VIII: wherein each R R Z is 2H or O; m is an integer from 1 to 3; (i) a moiety of formula IX: wherein each R each R R R provided one and only one of R (j) a moiety of formula X: wherein each R each R Q each m is independently an integer from 1 to 3; provided one and only one of R (k) a moiety of formula XIV: wherein R R R (l) a moiety of formula XV: wherein R each R R R Q m′ is 1 or 2; (m) a moiety of formula XVI: wherein each R R each R Q m is an integer from 1 to 3; provided one and only one of R (n) a moiety of formula XIX: wherein R R R R provided one and only one of R (o) a moiety of formula XX: wherein each R each R each m is independently an integer from 1 to 3; provided one and only one of R (p) a moiety of formula XXIV: wherein R (q) a moiety of formula XXVI: wherein R (s) a moiety of formula XXVII: wherein each R Q provided one and only one of R (t) a moiety of formula XXVIII: wherein each R R m is an integer from 1 to 3; and (u) a moiety of formula XXIX: wherein R R R provided one and only one of R and each X is a linker independently selected from a group of the formula: wherein m′ is an integer of from 0 to 20; X Z is at each separate occurrence is selected from the group consisting of alkylene, substituted alkylene, cycloalkylene, substituted cycloalkylene, alkenylene, substituted alkenylene, alkynylene, substituted alkynylene, cycloalkenylene, substituted cycloalkenylene, arylene, heteroarylene, heterocyclene, or a covalent bond; Y R, R′ and R″ at each separate occurrence are selected from the group consisting of hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, alkenyl, substituted alkenyl, cycloalkenyl, substituted cycloalkenyl, alkynyl, substituted alkynyl, aryl, heteroaryl and heterocyclic.