Patent ID: 6211156
Filing Date: 2001-04-03
Classification: A61K,A61P,C07K

Abstract:
A method for causing penile erection in a male animal, which comprises administering to said animal a peptide having the following formula:X-A-B-C-Y-NH.sub.2wherein:X is .alpha.-aminoisobutyryl, tranexamyl (i.e. 4-(aminomethyl) cyclohexanecarbonyl), isonipecotinyl, .gamma.-aminobutyryl, hydrogen, or imidazolylacetyl;A is D-2-methyl-tryptophan, D-.beta.-(2-naphthyl) alanine, or D-tryptophan;B is D-2-methyl-tryptophan, D-.beta.-(2-naphthyl) alanine, D-tryptophan, or is absent;C is D-2-methyl-tryptophan, phenylalanine, or is absent;Y is lysine or arginine;wherein D stands for the dextro isomer; or a pharmaceutically acceptable addition salt of the peptide, in an amount effective to cause said erection.