Patent ID: 6265417
Filing Date: 2001-07-24
Classification: C07C,C07D

Abstract:
A compound of Formula I ##STR8##or a pharmaceutically acceptable salt, ester, amide, or prodrug thereof whereinR.sub.1 is alkyl;R.sub.2 is selected from the group consisting of aryl and heteroaryl;the aryl or heteroaryl are optionally substituted;n is 0-2;A is selected from the group consisting of hydrogen, alkyl, and --X--R.sub.3 ;R.sub.3 is alkyl or haloalkyl;X is --C(O)-- or --S(O).sub.p --;p is 1-2;R.sub.4 and R.sub.5 are independently selected from the group consisting of hydrogen, alkyl and haloalkyl; orR.sub.1 and R.sub.5 together with the ring to which they are attached form a 5-, 6- or 7-membered sulfur-containing ring with 1-2 double bonds and 0-2 oxo substituents; orA and R.sub.4 together with the ring to which they are attached form a ring selected from the group consisting of a 5-, 6-, or 7-membered carbocyclic ring with 1-2 double bonds and 0-1 oxo substituents and a 5-, 6- or 7-membered sulfur-containing ring with 1-2 double bonds and 0-2 oxo substituents, provided that one of R.sub.1 and R.sub.5 or A and R.sub.4 forms a ring.