Patent ID: 8383378
Filing Date: 2013-02-26
Classification: B01L,C12M

Abstract:
1. A method of patterning of biological materials of interest at specific sites on a plate, the materials of interest comprising cells, tissues, DNA or living organisms, the method comprising the steps of submerging a plate having a body in a solution containing a biological material of interest in suspension, the biological material of interest including one of cells, tissues, DNA and living organisms, the plate including a plurality of elevated sites extending from a surface of the body and a plurality of troughs extending contiguously across the body in a crisscrossing configuration separating each of the plurality of elevated sites from one another, forming a contiguous gas bubble within the plurality of troughs, the contiguous gas bubble isolating each of the plurality of elevated sites from one another, and adhering the biological material of interest to a top surface of the plurality of elevated sites on the body of the plate, wherein the contiguous gas bubble preventing the biological material of interest from adhering to surfaces within the plurality of troughs, and releasing one or more of the plurality of elevated sites from the plate with biological material of interest adhered to the top surface of the released one or more of the plurality of elevated sites, wherein the released one or more of the plurality of elevated sites acting as a carrier for the biological material of interest adhered thereto, and wherein the plurality of elevated sites are attached to and extending up from the body of the plate and the nature of the attachment of the plurality of elevated sites to the body of the plate is releasable leaving the structure of the body of the plate intact when one or more of the plurality of elevated sites is released from the body of the plate.