Patent ID: 8530453
Filing Date: 2013-09-10
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A method of treating an MMP mediated condition, comprising orally administering to a subject an effective amount of a compound of Formula 5 or 10: including N-oxides, pharmaceutically acceptable salts, formulations, polymorphs, tautomers, racemic mixtures and stereoisomers thereof; and the MMP mediated condition is selected from enhanced or exaggerated sensitivity to pain; acute pain; burn pain; atypical facial pain; neuropathic pain; back pain; complex regional pain syndromes I and II; arthritic pain; sports injury pain; pain related to viral infection; phantom limb pain; cancer pain; post-operative pain; nociceptive pain; inflammatory pain; visceral pain; neuropathic pain; neuralgia; neuropathy related to diabetes; hyperalgesia and withdrawal pain related to use of narcotics.