Patent ID: 8999916
Filing Date: 2015-04-07
Classification: A61K,A61L,A61P,C12N

Abstract:
1. A hydrogel comprising a plurality of amphiphilic peptides and/or peptoids capable of self-assembling into three-dimensional macromolecular nanofibrous networks, which entrap water and form said hydrogel, the amphiphilic peptides and/or peptoids having the general formula: wherein Z is an N-terminal protecting group, X is, at each occurrence, independently selected from an aliphatic amino acid, Y is, at each occurrence, independently selected from a hydrophilic amino acid, AA Z′ is a C-terminal protecting group, n is an integer selected from 2 to 6, m is selected from 0, 1 and 2, and p and q are independently selected from 0 and 1, wherein at least a portion of said plurality of amphiphilic peptides and/or peptoids is chemically cross-linked.