Patent ID: 6303754
Filing Date: 2001-10-16
Classification: A61K,A61P,C07K

Abstract:
A polypeptide, comprising an amino acid sequence, said amino acid sequence being selected from the group consisting of:(a) from position about -22 to position about 1620 of the amino acid sequence shown in FIG. 2 (SEQ ID NO: 2) with 1 to 8 histidine residues added to the carboxy terminus;(b) from position about 1 to position about 1620 of the amino acid sequence shown in FIG. 2 (SEQ ID NO: 2) with 1 to 8 histidine residues added to the carboxy terminus;(c) from position about 1 to position about 1620 of the amino acid sequence shown in FIG. 2 (SEQ ID NO: 2) with 1 to 8 histidine residues added to the carboxy terminus and a methionine residue added to the amino terminus;(d) from position about 1 to position about 1620 of the amino acid sequence shown in FIG. 2 (SEQ ID NO: 2) with the signal peptide of the baculovirus glycoprotein gp67 (sequence I) added to the amino terminus and with 1 to 8 histidine residues added to the carboxy terminus; andwherein sequence I (gp67 signal peptide) is: MLLVNQSHQGFNKEHTSKMVSAIVLYVLLAAAAHSAFA (SEQ ID NO:36).