Patent ID: 7253158
Filing Date: 2007-08-07
Classification: A61P,C07D

Abstract:
1. A compound of formula I wherein R R R or is aryl or is heteroaryl selected from the group consisting of pyridyl, pyrazinyl, pyrimidinyl, pyridazinyl, triazinyl, thiazolyl, thienyl, furyl, pyrrolyl, imidazolyl, pyrazolyl, isothiazolyl, tetrazolyl, [1,2,4]triazolyl, [1,2,4]oxadiazolyl, oxazolyl, indanyl, benzo[1,3]dioxolyl, benzofuranyl and isoxazolyl, each of which is substituted by or is cycloalkyl; R′ is hydrogen, R″ is hydrogen, R is hydrogen or lower alkyl; R X is —CHR—; and m is 0, 1, 2 or 3; or a pharmaceutically acceptable acid addition salt, optically pure enantiomer, racemate or diastereomeric mixture thereof.