Patent ID: 7618522
Filing Date: 2009-11-17
Classification: A61B,C12Q,G01N,Y02A

Abstract:
1. A method of reducing interferences in an electrochemical sensor having a sample chamber with first and second working electrodes disposed in the chamber, the working electrodes including a reagent disposed thereon, the method comprising: contacting a sample of physiological fluid with the working electrodes and reagent, the physiological fluid including at least an analyte disposed therein; applying a first potential to the first working electrode to initiate a chemical reaction; applying a second potential to the second working electrode to initiate a chemical reaction, wherein said second potential is greater than the absolute value of said first potential; measuring a first current, at said first working electrode, which comprises an analyte current and an interfering compound current; measuring a second current, at said second working electrode, which comprises an analyte overpotential current and an interfering compound overpotential current, wherein said analyte overpotential current has a first directly proportional relationship to said analyte current, the first directly proportional relationship comprising where X is said analyte voltage effect factor derived from calibration test data of the sensor, A where Y is said interfering compound voltage effect factor, I calculating a corrected current value representative of an analyte concentration of the physiological fluid using an equation which is a function of said first current, said second current, said first directly proportional relationship, and said second directly proportional relationship.