Patent ID: 6313314
Filing Date: 2001-11-06
Classification: C07D

Abstract:
A method for the preparation of azide photo-initiators comprising:a. substitution reacting compound II and MN.sub.3 in a ketone solvent to obtain compound III, wherein M is hydrogen or alkaline metal and compound II and compound III are as follows: ##STR6##wherein R.sub.1 is hydrogen, halogen or alkyl of 1-4 carbon atoms, X is halogen, and n is 1 or 2.b. de-protecting the acetyl-amino of compound III in acid condition, adding alkaline solution to the resulting solution to adjust the pH to be greater than 7, and extracting by organic solvent to obtain compound IV: ##STR7##c. addition reacting the resulting organic solvent extract with compound V to obtain compound VI: ##STR8##wherein R.sub.2 and R.sub.3 are independently the same or different and each represent hydrogen, alkyls of 1-6 carbon atoms, or cycloalkyl, or R.sub.2 and R.sub.3 combined together represent cycloalkenyl, aryl or heteroaryl; andd. dehydrating compound IV by acetic anhydride and metal acetate to obtain azide photo-initiator compound I; ##STR9##wherein R.sub.1, R.sub.2, R.sub.3 and n are defined as above.