Patent ID: 8603516
Filing Date: 2013-12-10
Classification: A61J,A61K,A61P

Abstract:
1. A glassy lozenge for buccal drug delivery comprising: a) a non-crystalline matrix having a hydrogel structure; b) an active agent selected from an anti-emetic agent, an agent for migraine treatment, and an analgesic agent; c) water; and d) optionally one or more components selected from flavorings, taste masking agents, colorings, buffering agents, pH adjusting agents, excipients, stabilizers and sweeteners, wherein the matrix comprises (i) at least one gum and (ii) at least one non-crystallising sugar or non-crystallising sugar alcohol; wherein the matrix comprises, by weight, from 40-90% of gum component (i), and from 60-10% of the non-crystallising sugar or non-crystallising sugar alcohol component (ii) and wherein the lozenge dissolves or disintegrates gradually.