Patent ID: 6572873
Filing Date: 2003-06-03
Classification: A61K,A61P,B05B,B65D,Y10S

Abstract:
A method for producing a microfoam suitable for use in sclerotherapy of blood vessels said microfoam comprising gas bubbles in which at least 50% by number of the gas bubbles of 25 &mgr;m diameter and above are of no more than 200 &mgr;m diameter and at least 95% of these gas bubbles are no more than 280 &mgr;m diameter, said method comprising passing a mixture of a physiologically acceptable blood dispersible gas capable of being substantially completely dissolved in or absorbed by blood and an aqueous sclerosant liquid through one or more passages having at least one cross-sectional dimension of from 0.1 to 30 &mgr;m, the ratio of gas to liquid being controlled such that a microfoam is produced having a density of between 0.07 g/mL to 0.19 g/mL and has a half-life of at least 2 minutes, to produce said microfoam, said microfoam being formed without the prior step of beating with a brush.