Patent ID: 6693178
Filing Date: 2004-02-17
Classification: C07H,Y02P

Abstract:
A compound represented by general structure 53: whereinD represents an optionally substituted alllopyranoside, altropyranoside, gulopyranoside, idopyranoside, talopyranoside, arabinofuranoside, or lyxofuranoside; M represents O, S, or NR; R represents independently for each occurrence H, alkyl, acyl, aryl or heteroaromatic; Z represents Cl, Br, or I; hetereoaromatic represents independently for each occurrence an aromatic group with 5-7 ring atoms, of which one to four are S, O and/or N; Ar represents a monocyclic or polycyclic aryl or heteroaromatic groups that is optionally substituted with one or more substituents independently selected from the group consisting of halide, alkyl, alkenyl, alkynyl, hydroxyl, amino, nitro, sulfhydryl, â€”R9SR8, â€”C(O)N(R8)2, â€”Q2â€”P(Q1)R8(OR8), carboxyl, â€”R9C(O)OC(O)R8, silyl, â€”SR8, alkylsulfonyl, arylsulfonyl, â€”R9(O)CR8, â€”R9C(O)H, â€”R9C(O)OR, â€”OC(O)R, heteroalkyl, â€”R9CN, aryl, monocyclic or bicyclic heteroaromatic, and aralky; wherein CH2MD and Z are bonded to the same aromatic ring of Ar; R8 represents independently for each occurrence hydrogen, alkyl, alkenyl, alkynyl, or aryl; R9 represents independently for each occurrence a bond or an alkyl, alkenyl, alkynyl, or aryl biradical; Q1 represents independently for each occurrence S or O; and Q2 represents independently for each occurrence O, S, or NR8.