Patent ID: 9221826
Filing Date: 2015-12-29
Classification: A61P,C07D,C07F

Abstract:
1. A compound of Formula (II): or stereoisomers or salts thereof, wherein: R R L is —NHC(O)—, —NHC(O)O—, —NHS(O) R R a) phenyl substituted with zero to 2 substituents independently selected from b) heterocycle selected from azetidinonyl, pyrrolidinonyl, morpholinonyl, pyridinonyl, imidazolidinonyl, oxazolidinonyl, propane-1,3-sultam, butane-1,4-sultam, 5-thioxo-4,5-dihydro-1,3,4-oxadiazoly-2-yl, and 5-methylthio-1,3,4-oxadiazoly-2-yl, wherein said heterocycle is substituted with zero to 1 substituent selected from C c) heteroaryl selected from pyrrolyl, pyrazolyl, thiazolyl, oxadiazolyl, pyridinyl, pyrimidinyl, pyrazinyl, indolyl, quinolinyl, 3,4-dihydroisoquinolin-1(2H)-onyl, benzo[d][1,3]dioxolyl, quinolin-2(1H)-onyl, benzothiazolyl, 1H-benzo[d]imidazol-2(3H)-onyl, wherein said heteroaryl is substituted with zero to 3 substituents independently selected from F, Cl, —OH, —CN, C