Patent ID: 6080755
Filing Date: 2000-06-27
Classification: A61P,C07D

Abstract:
A diazabicyclo compound of the formula (I): ##STR54## wherein R.sup.1 is a group selected from the following: (1) a lower alkyl group or lower alkenyl group which may be substituted by a cyano, nitro, lower alkylthio, lower alkylsulfinyl or lower alkylsulfonyl group,(2) a lower acyl group having an alkyl moiety of 1 to 4 carbon atoms which may be substituted by an imidazolyl, pyridyl, oxazolyl, thiazolyl, or thiadiazolyl group,(3) a 2-pyridyl, azetidinyl, pyrrolidinyl, imidazolyl, imidazolinyl, piperidinyl, pyrazolidinyl, tetrahydropyrimidinyl, morpholinyl, 1,3-oxazolin-2-yl, 1-oxa-2,4diazol-3-yl, 1,2,4-triazol-3-yl, thiazolidinyl, or 1-thia-3,5-diazolidin-2-yl group which may be substituted by a lower alkyl or lower alkoxycarbonyl group, and(4) a carbonyl group substituted by an imidazolyl, pyridyl, piperazinyl, oxazolyl, thiazolyl, or thiadiazolyl group,R.sup.2 is a hydroxy group,R.sup.3 is a lower alkoxycarbonyl group,R.sup.4 and R.sup.7, each of them being the same as the other, are hydrogen atoms or phenyl groups which may be substituted by a halogen, cyano, lower alkyl, lower alkoxy, nitro, aryl or lower acyl group having an alkyl moiety of 1 to 4 carbon atoms, andR.sup.5 and R.sup.6, each of them being the same as the other, are hydrogen atoms or lower alkyl groups, ora pharmaceutically acceptable salt thereof.