Patent ID: 9198910
Filing Date: 2015-12-01
Classification: A61K

Abstract:
1. A method of treating endocrine cancer in a subject, the method comprising the steps of: receiving a sample of a tumor from the subject; adding a reagent to a mixture comprising the sample, the reagent specifically binds to a first marker having a sequence selected from the group consisting of SEQ ID NO. 1, SEQ ID NO. 2, SEQ ID NO. 4, and SEQ ID NO. 5; subjecting the mixture to conditions that allow detection of binding of the reagent to the first marker; assessing an expression level of the first marker in the sample based on a level of binding of the reagent to the marker; and detecting reduced expression of the first marker in the sample as compared to a control sample and administering a therapeutically effective amount of a pharmaceutical composition comprising a mitotic catastrophe inducing composition to the subject.