Patent ID: 8906876
Filing Date: 2014-12-09
Classification: A01N,A61K,C07K,C12N,Y02A

Abstract:
1. An isolated double stranded RNA molecule comprising annealed complementary strands, wherein at least one of said strands comprises a polyribonucleotide selected from the group consisting of: (i) polyribonucleotides complementary to at least 21 contiguous nucleotides of a target gene represented by SEQ ID NO: 2493 or SEQ ID NO: 11, or the complement thereof, (ii) polyribonucleotides complementary to at least 21 contiguous nucleotides of a target gene encoding the amino acid sequence represented by SEQ ID NO: 2494, and (iii) polyribonucleotides having at least 85% sequence identity with the polyribonucleotides of (i) or (ii), wherein ingestion of said double stranded RNA molecule inhibits expression of said target gene.