Patent ID: 6794522
Filing Date: 2004-09-21
Classification: C07B,C07C,C07D

Abstract:
A method of preparing a deuterium labeled or tritium labeled compound comprising contacting an organic substrate with a catalyst having the at least one of the following structures: where M is selected from the group consisting of Co, Rh or Ir; A1 and A2 each independently represent ligands that are a 6 electron donor; L1 and L2 each independently represent ligands that are a 2 electron donor; X1, X2, X3, X4 and X5 each independently represent ligands that are a two electron donor; Y is an anion capable of creating a charge neutral complex, and contacting the organic substrate and said catalyst with a source of deuterium or tritium and heating the combination at a temperature of from 75-200Â° C.