Patent ID: 9115212
Filing Date: 2015-08-25
Classification: A61K,A61P,A61Q,C07K

Abstract:
1. A bifunctional peptide activating synthesis of collagen and inhibiting production of matrix metallo-proteinases, said peptide comprising: a sequence comprising a first peptide portion A, a second peptide portion B, and a third peptide portion C, wherein the first peptide portion A corresponds to a hexapeptide repeated at least three times, said first peptide portion A bonding to an elastin-binding receptor protein in order to stimulate collagen synthesis, wherein the second peptide portion B corresponds to a tetrapeptide acting as a competitive inhibitor of urokinase protease and being cleaved by said urokinase protease, and wherein the third peptide portion C corresponds to a tripeptide occupying at least one active site of the matrix metallo-proteinases in order to permit an inhibition of said proteinases.