Patent ID: 6140338
Filing Date: 2000-10-31
Classification: C07D

Abstract:
A compound of the formula: ##STR10## wherein each of R.sup.1 and R.sup.2, which are the same or different, is hydrogen, halogen, lower alkyl, lower alkenyl, lower alkynyl, hydroxy lower alkyl, lower alkoxy, lower alkoxycarbonyl, aralkyloxycarbonyl, formyl, carbamoyl, lower alkylaminocarbonyl, di-lower alkylaminocarbonyl, lower alkoxycarbonyl(lower)alkylaminocarbonyl aralkyloxy-carbonyl(lower)alkylaminocarbonyl, aralkylaminocarbonyl, diaralkylaminocarbonyl or heteroaryl(lower)alkylaminocarbonyl, wherein the heteroaryl group of the heteroaryl(lower) alkylaminocarbonyl contains one to three heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur, and when it contains at least one nitrogen, it optionally forms a quaternary salt with a lower alkyl group or a lower alkenyl group; X is oxygen, sulfur or CH; Y is CH; A is a group of the formula: ##STR11## wherein each of m and n is from 1 to 3, m+n is from 3 to 5, p is from 1 to 3, each of r, s and t which are the same or different, is from 0 to 3, r+s+t is from 2 to 3, and Z is a group of the formula: ##STR12## wherein R.sup.3 is C.sub.5-15 saturated or unsaturated aliphatic hydrocarbon; R.sup.4 is lower alkyl or lower alkenyl, and Q- is an anion, or a pharmaceutically acceptable salt thereof, or a hydrate thereof.