Patent ID: 7745417
Filing Date: 2010-06-29
Classification: C07H

Abstract:
1. A nucleoside or nucleotide having a 5-substituted-2-oxo(1H)-pyridin-3-yl group as a base, wherein the 5-position of the base is substituted with a substituent selected from the group consisting of the following: 1) a photoreactive group selected from iodine and bromine; 2) biotin or a derivative thereof; 3) a fluorescent molecule selected from fluorescein, 6-carboxyfluorescein, and tetramethyl-6-carboxyrhodamine; and 4) an aminoalkyl linker or an aminoalkenyl linker linked to biotin, dichloroacetyl group, fluorescein, 6-carboxyfluorescein, tetramethyl-6-carboxyrhodamine, or derivatives thereof.