Patent ID: 6271392
Filing Date: 2001-08-07
Classification: C07D

Abstract:
A compound of the formula: ##STR11##wherein:W is cyano, --CO.sub.2 H, --CO.sub.2 R.sub.3, --CONH.sub.2, --CONHR.sub.3, --CON(R.sub.3).sub.2, --CSNH.sub.2, --CSNHR.sub.3, --CSN(R.sub.3).sub.2, --COSH, --COSR.sub.3, --CHO, --CH.dbd.NOH, --CH.dbd.NOR.sub.3, or nitro;R is alkyl, haloalkyl, cyano, --C(NH.sub.2)(.dbd.NH) or an acid addition salt thereof, hydrogen, or ##STR12##R.sub.1 and R.sub.2 independently represent hydrogen, halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, alkylsulfenyl, alkylsulfinyl, alkylsulfonyl, haloalkylsulfenyl, haloalkylsulfinyl, haloalkylsulfonyl, cyano, nitro, NR.sub.11 R.sub.12, formyl, alkylcarbonyl, haloalkylcarbonyl, hydroxyalkylcarbonyl, --CO.sub.2 H, --CO.sub.2 R.sub.3, alkylthiocarbonyl, --CONH.sub.2, --CONHR.sub.3, --CON(R.sub.3).sub.2, bis(alkoxy)methyl, bis(alkylthio)methyl, (alkoxy)(cyano)methyl, (acyloxy)(cyano)methyl, (phenoxy)(cyano)methyl, (alkoxy)(alkylthio)methyl, (alkylamino)(alkoxy)methyl, (alkoxy)(dialkylamino)methyl, (alkylamino)(alkylamino)methyl, (dialkylamino)(dialkylamino)methyl, (alkoxy)(alkoxycarbonyl)methyl, (alkoxy)(aminocarbonyl)methyl, (alkoxy)(alkylaiinocarbonyl)methyl, (alkoxy)(dialkylaminocarbonyl)methyl, alkoxyalkyl, hydroxyalkyl, (haloalkoxy)alkyl, (alkoxy)(haloalkyl)alkyl, cyanoalkyl, halogenated cyanoalkyl, alkoxycarbonylalkyl, aminocarbonylalkyl, monoalkylaminocarbonylalkyl, formylalkyl, dialkylaminocarbonylalkyl, alkoxyalkylcarbonyl, alkylsulfenylalkylcarbonyl, alkylsulfmylalkylcarbonyl, alkylsulfonylalkylcarbonyl, cyanoalkylcarbonyl, alkoxycarbonylalkylcarbonyl, aminocarbonylalkylcarbonyl, monalkylaminocarbonylalkylcarbonyl, dialkylaminocarbonylalkylcarbonyl, --CH.dbd.N--O--R.sub.11, amino(thio)carbonyl, monoalkylamino(thio)carbonyl, dialkylamino(thio)carbonyl, or a radical of the formula ##STR13##wherein:R.sub.13 is hydrogen, alkyl, or haloalkyl;Y and Z are O, S, SO, SO.sub.2, NH, N-alkyl, or N-acyl;Q is ethylene or propylene optionally substituted with alkyl, haloalkyl, alkoxy, alkoxyalkyl, cyano, hydroxyalkyl, amino, alkylamino, dialkylamino, alkylsulfenyl, alkylsulfmyl, alkylsulfonyl, OH, or SH;s is 0 to 3;R.sub.3 is alkyl, haloalkyl, hydroxyalkyl or alkoxyalkyl;R.sub.11, and R.sub.12 independently represent H, alkyl, haloalkyl, formyl, alkylcarbonyl, haloalkylcarbonyl, alkoxycarbonyl, haloalkoxycarbonyl, aminocarbonyl, monoalkylaminocarbonyl, dialkylaminocarbonyl, alkylsulfonyl, haloalkylsulfonyl, alkylsulfinyl, haloalkylsulfimyl, allyl, propargyl, halogen, alkoxyalkyl, alkylthioalkyl, alkylsulfinylalkyl, alkylsulfonylalkyl, haloalkoxyalkyl, haloalkylthioalkyl, haloalkylsulfmylalkyl, haloalkylsulfonylalkyl, aminoalkyl, monoalkylaminoalkyl, dialkylaminoalkyl, or alkoxycarbonyl; andn is 0, 1 or 2,provided that when R.sub.1 is methyl, then R.sub.2 is not hydrogen or alkyl, W is not --CO.sub.2 R.sub.3 and n is not 0; andprovided that when W is --CO.sub.2 C.sub.2 H.sub.5, then R is not --C(NH.sub.2)(.dbd.NH) or an acid addition salt thereof.