Patent ID: 9144562
Filing Date: 2015-09-29
Classification: A61K,A61P

Abstract:
1. A method for reducing adverse cytokine production comprising administering to a subject in need thereof a therapeutically effective amount of an omega-3 lipid-based oil-in-water emulsion suitable for administration to a subject, wherein (a) the emulsion comprises at least about 7% to about 35% omega-3 oil by weight in grams per 100 ml of emulsion, (b) the omega-3 oil comprises at least about 20% omega-3 diglyceride by weight per total weight of the omega-3 oil, and at least about 70 wt.-% of the acyl-groups of the omega-3 diglycerides comprise EPA, DHA or a mixture thereof, (c) the omega-3 oil comprises less than about 10% omega 6 fatty acids, and (d) the mean diameter of lipid droplets in the emulsion is less than about 5 microns, wherein the cytokines are pro-inflammatory cytokines.