Patent ID: 8741348
Filing Date: 2014-06-03
Classification: A61K,A61P

Abstract:
1. A pharmaceutically acceptable, nicotine-containing, particulate material for relatively fast release of the nicotine upon contact with a human subject, the material comprising a combination of: a) a particulate microcrystalline excipient having suitable porous structure and bulk density for allowing nicotine to sorb in the porous structure of the excipient upon contact; and b) at least 0.5 milligrams of nicotine sorbed within the porous structure, the particulate material having a concentration of nicotine of 0.1 to 8% (w/w), and wherein the nicotine sorbed within the porous structure is chemically and/or physically stable for at least 22 weeks when stored at a temperature of 40° C. and a relative humidity of 50%.