Patent ID: 8603820
Filing Date: 2013-12-10
Classification: C08J,C12M,C12N

Abstract:
1. A method for making a cell culture article comprising: diluting at least three (meth)acrylate monomers in a solvent wherein at least one of the at least three (meth)acrylate monomers has an N-hydroxysuccinimide moiety; dispersing the diluted monomers on a surface of a cell culture substrate; removing about 80% or more of the solvent; and polymerizing the monomers on the surface of the cell culture substrate after removing the about 80% or more of the solvent to form a synthetic polymer layer having N-hydroxysuccinimide moieties on the surface of the cell culture substrate; and, conjugating a cell adhesive peptide to the synthetic polymer layer through the N-hydroxysuccinimide moieties.