Patent ID: 6576785
Filing Date: 2003-06-10
Classification: C07C

Abstract:
A compound of the formula in which R10 is C1-6 alkyl, R11 is C1-4 alkyl, C1-4 alkoxy, phenyl, phenyl-C1-4 alkyl, R14-OOC-C1-4 alkyl or R14 -OOC-C2-4 alkenyl (in which R14 is hydrogen atom or C1-4 alkyl; R2 is hydrogen atom, hydroxy or C1-4 alkoxy; R3 is (i) hydrogen atom, (ii) C1-8 alkyl, (iii) C2-8 alkenyl, (iv) C2-8 alkynyl or (v) C1-8 alkyl, C2-8 alkenyl or C2-8 alkynyl, each substituted by 1-3 substituents, being same or different, selected from (1)-(5); (1) halogen atom, (2) C1-4 alkoxy, (3) C3-7 cycloalkyl, (4) phenyl, or (5) phenyl substituted by 1-3 substitutents selected from halogen atom, C1-4 alkyl, C1-4 alkoxy, nitro or trifluoromethyl; n is 0-4; â€ƒâ€ƒis double bond or triple bond; â€ƒâ€ƒis single bond, double bond or triple bond; with the proviso that, 1) when 5-6 position is triple bond, 13-14 position is not triple bond, 2) when 13-14 position is double bond represent E or Z form; non-toxic salt thereof, and cyclodextrin clathrate thereof. wherein R11 is C1-4 alkyl, C1-4 alkoxy, phenyl, phenyl-C1-4 alkyl, R14â€”OOCâ€”C1-4 alkyl or R14â€”OOCâ€”C2-4 alkenyl (in which R14 is hydrogen atom, C1-4 alkyl), the other symbols are the same meaning as hereinbefore defined.