Patent ID: 6291198
Filing Date: 2001-09-18
Classification: C07K,G01N,Y10S

Abstract:
An antibody that recognizes at least a region comprising R.sup.1, R.sup.2, carbon atoms in the pyrazine ring to which R.sup.1 and R.sup.2 are respectively attached, and nitrogen atoms in the pyrazine ring attached to said carbon atoms, of a pyrazine derivative represented by the formula (I): ##STR20##wherein R.sup.1 and R.sup.2 independently represent a hydrogen atom, a methyl group, a hydroxymethyl group, a hydroxyethyl group, a dihydroxyethyl group, a dihydroxypropyl group, a trihydroxypropyl group, or a trihydroxybutyl group, A represents a group that binds to the pyrazine ring to form a 6-membered aromatic hydrocarbon group, a 5- or 6-membered aromatic heterocyclic group, or a 5- or 6-membered alicyclic hydrocarbon group, wherein R.sup.3 represents a linking residue, and wherein said 5-membered ring formed by A may have 1 or 2 substituents and said 6-membered ring may have 1 to 3 substituents, in addition to R.sup.3.