Patent ID: 6380257
Filing Date: 2002-04-30
Classification: A61P,C07C,C07D

Abstract:
A compound of formula I wherein:R4, R5, R6 and R7 are independently selected from H, OH, halogen, alkyl, aryl, acyl, X-alkyl, and X-aryl, wherein X is O, NH, N-alkyl, or S, and wherein alkyl, acyl, and aryl are optionally substituted; K is a group of formula II or III: L is a group of formula IV or V: or K and L form, together with the respective carbon atoms to which they are bound, a group of formula VI, VII, or VIII: wherein:R1 and R3 are independently selected from a cation, H, alkyl, and aryl; R2 is H, alkyl, aryl, or acyl; X1, X2, X3, X4, X5, X6, and X7 are independently selected from O, NH, N-alkyl, and S, and Cyclus is, together with the C atoms marked c and d, an optionally substituted saturated, partly unsaturated, or aromatic, carbocyclic or heterocyclic, simple or condensed ring system, or a pharmaceutically acceptable salt, ester, or ether, or other chemical equivalent, in any stereoisomeric or tautomeric form, or a mixture thereof in any ratio;with the exclusion of compounds wherein K is a group of formula II, and L is a group of formula IV in which X1, X2, X3, X4, X5, X6 and X7 are O, R1, R2 and R3 are H, R4 is OH, R5, R6 and R7 are H and Cyclus is 3,8-dihydroxyanthraquinone, and with the exclusion of compounds wherein K and L form together a group of formula VI in which X1, X2, X3, X4, X5, X6 and X7 are O, R1 is â€”CH3, R2 and R3 are H, R4 is OH, R5, R6 and R7 are H, and Cyclus is 3,8-dihydroxyanthraquinone.