Patent ID: 9045441
Filing Date: 2015-06-02
Classification: A61P,C07D,C07F

Abstract:
1. A compound of the formula (I) or a pharmaceutically acceptable salt, solvate, or hydrate thereof, wherein A is selected from the group consisting of —CO—O—, —O—CO—, —NH—CO—, —CO—NH, —C═C—, —CCH ring structure B optionally contains one nitrogen atom; R2 is selected from the group consisting of a H, a (1-4C)alkyl optionally substituted with at least one fluoro atom, a (1-4C)alkoxy optionally substituted with at least one fluoro atom, and a halogen; and R3 is selected from the group consisting of R4 is selected from the group consisting of H and a (1-4C)alkyl; R5 is selected from the group consisting of —OH, —OPO R6 is at least one substituent, and each R6 substituent is independently selected from the group consisting of H, a (1-4C)alkyl, and an oxo; and W is —O—; with the proviso that the compound of formula (I) is not 2-(4-ethylphenyl)-4-morpholinoethanol, 2-(4-ethylphenyl)-4-morpholinoethanol hydrochloride, 4-[4-(2-hydroxyethyl)-2-morpholinyl]benzeneacetonitrile, 4-[4-(2-hydroxyethyl)-2-morpholinyl]benzeneacetonitrile hydrochloride, or 3-methyl-2-[4-(phenylmethoxy)phenyl]-4-morpholinoethanol hydrochloride.