Patent ID: 6159694
Filing Date: 2000-12-12
Classification: A61K,A61P,C12N,Y02P

Abstract:
An antisense compound 8 to 30 nucleobases in length targeted to nucleobases 64-83 of a translation initation region, nucleobases 96-2328 of a coding region, nucleobases 2374-2393 of a stop codon region or nucleobases 2485-2841 of a 3'-untranslated region of mouse STAT3 (SEQ ID NO:82) or nucleobases 10-149 of a 5'-untranslated region, nucleobases 224-2503 of a coding region, nucleobases 2525-2552 of a stop codon region or nucleobases 2569-2779 of a 3'-untranslated region of human STAT3 SEQ ID NO:1, wherein said antisense compound inhibits the expression of said human or mouse STAT3.