Patent ID: 8980220
Filing Date: 2015-03-17
Classification: A61K,C07K,G01N

Abstract:
1. A molecular probe comprising any one of the following polypeptides: a polypeptide represented by the following formula (1), (2), or (3); a polypeptide that is obtained by deletion, insertion, or substitution of one, two or three amino acids with respect to the polypeptide represented by the following formula (1), (2), or (3) and binds to pancreatic islets; and a polypeptide that has a sequence identity of 85% or higher with the amino acid sequence of the polypeptide represented by the following formula (1), (2), or (3) and binds to pancreatic islets: wherein in the formulae (1) and (2), “X” represents a lysine residue, an amino group of a side chain of the lysine residue being labeled with a radioactive nuclide, and “Z—” indicates that an α-amino group at an N-terminus is not modified, or is modified with a modifying group having no electric charge, in the formula (3), “B—” indicates that an α-amino group at an N-terminus is labeled with a radioactive nuclide, and in the formulae (1), (2), and (3), “—NH