Patent ID: 6214580
Filing Date: 2001-04-10
Classification: A61K,A61P,C07K,C12N

Abstract:
An isolated nucleic acid molecule comprising a polynucleotide sequence selected from the group consisting of:(a) a polynucleotide sequence encoding amino acid residues -55 to 331 of SEQ ID NO:2;(b) a polynucleotide sequence encoding amino acid residues -54 to 331 of SEQ ID NO:2;(c) a polynucleotide sequence encoding amino acid residues 1 to 157 of SEQ ID NO:2;(d) a polynucleotide sequence encoding amino acid residues 158 to 175 of SEQ ID NO:2;(e) a polynucleotide sequence encoding amino acid residues 176 to 331 of SEQ ID NO:2;(f) a polynucleotide sequence encoding amino acid residues 298 to 308 of SEQ ID NO:2; and(g) a polynucleotide sequence encoding a fragment of the polypeptide of SEQ ID NO:2 wherein said fragment binds a Tumor Necrosis Factor (TNF)-family ligand.