Patent ID: 6287872
Filing Date: 2001-09-11
Classification: B01J,B01L,C40B,G01N,H01J,Y10T

Abstract:
A method of preparing samples for mass spectrometric analysis using matrix-assisted laser desorption (MALDI), the method comprising:providing an electrically conductive sample support plate with a substantially flat surface and a plurality of anchor sites each of which is more hydrophilic than a hydrophobic area immediately surrounding it;applying a liquid sample material to the sample support plate in droplets each of which is applied to the sample support plate in the vicinity of a different one of the anchor sites and is correspondingly drawn thereto, the droplets being at least twice as large in diameter as the anchor sites; anddrying the sample liquid such that residual sample material from each droplet is concentrated onto the respective anchor site with which it is associated.