Patent ID: 6344565
Filing Date: 2002-02-05
Classification: C07D

Abstract:
A process for producing 2-oxo-1,3-dibenzyl-cis-4,5-imidazolidinedicarboxylic acid comprising:(a) reacting meso-2,3-bis(benzylamino)-succinic acid dialkali metal salt with triphosgene in a two-phase solvent system consisting of an aqueous phase of an aqueous alkali hydroxide solution and an organic phase of an organic solvent at a temperature below about 50Â° C.; and (b) acidifying the resulting 2-oxo-1,3-dibenzyl-cis-4,5-imidazolidinedicarboxylic acid dialkali metal salt in the aqueous phase to form 2-oxo-1,3-dibenzyl-cis-4,5-imidazolidinedicarboxylic acid.