Patent ID: 8574604
Filing Date: 2013-11-05
Classification: A61K,A61L,A61P,C08G

Abstract:
1. A polymer described by the formula: wherein F Bio is one or more biologically active agents capable of being complexed to LINK A; each LINK A is, independently, an organic moiety comprising a complexing moiety that is tri-hydroxymethyl aminoethane (Tris); oligo is an oligomeric segment; T is a terminal group; a is 0 or 1; b, c, d, and e are integers greater than 0; and wherein at least one Bio is complexed via hydrogen bonding interactions to at least one LINK A, and wherein each Bio is selected from the group consisting of antibiotics, antiproliferative agents, rapamycin macrolides, analgesics, anesthetics, antiangiogenic agents, antithrombotic agents, vasoactive agents, anticoagulants, immunomodulators, cytotoxic agents, antiviral agents, psychoactive drugs, vitamins, lipids, and prodrugs thereof.