Patent ID: 6100292
Filing Date: 2000-08-08
Classification: C07D

Abstract:
A ketone derivative represented by the following general formula (I) ##STR16## where A is general formula (II) or (III) ##STR17## m is the integer 1 or 2, R.sub.1 to R.sub.7 are each independently a hydrogen atom or a substituent selected from the group consisting of a fluorine atom, chlorine atom, bromine atom, C.sub.2 to C.sub.19 alkyl groups, C.sub.1 to C.sub.19 alkenyl groups, C.sub.6 to C.sub.12 aryl groups, C.sub.6 to C.sub.12 aryl groups with a C.sub.1 to C.sub.19 alkyl group, C.sub.1 to C.sub.19 alkyl groups with a C.sub.6 to C.sub.12 aryl group, C.sub.6 to C.sub.12 aryl groups with a C.sub.2 to C.sub.19 alkenyl group, C.sub.2 to C.sub.19 alkenyl groups with a C.sub.6 to C.sub.12 aryl group, the hydroxyl group, C.sub.1 to C.sub.10 alkoxy groups, the nitro group, carboxyl group, C.sub.2 to C.sub.10 alkoxycarbonyl groups, and the cyano group, or R.sub.1 and R.sub.2 are together --CH.dbd.CH--CH.dbd.CH--, R.sub.5 and R.sub.6 are together --CH.dbd.CH--CH.dbd.CH-- or --(CH.sub.2).sub.q -- where q is an integer in the range 2 to 5, or R.sub.6 and R.sub.7 are together --(CH.sub.2).sub.r -- where r is an integer in the range 2 to 5,R.sub.8 and R.sub.9 are each independently a hydrogen atom, or a substitutent selected from the group consisting C.sub.2 to C.sub.6 alkyl groups, C.sub.1 to C.sub.6 alkenyl groups, C.sub.6 to C.sub.12 aryl groups, C.sub.6 to C.sub.12 aryl groups with a C.sub.1 to C.sub.19 alkyl group, C.sub.1 to C.sub.19 alkyl groups with a C.sub.6 to C.sub.12 aryl group, C.sub.6 to C.sub.12 aryl groups with a C.sub.2 to C.sub.19 alkenyl group, C.sub.2 to C.sub.19 alkenyl groups with a C.sub.6 to C.sub.12 aryl group, C.sub.2 to C.sub.10 alkoxycarbonyl groups, or R.sub.8 and R.sub.9 are together --(CH.sub.2).sub.4 -- or --(CH.sub.2).sub.5 --,R.sub.10 is a fluorine atom, chlorine atom or bromine atom, R.sub.11 is a C.sub.1 to C.sub.6 alkyl group or C.sub.6 to C.sub.12 aryl group, or R.sub.10 and R.sub.11 are together --CH.dbd.CH--CH.dbd.CH-- or --(CH.sub.2).sub.t -- where t is an integer in the range 2 to 5,X is O or S,Z is a hydrogen atom or methyl group,Y is O or S,n is 0 or 1, or a pharmacologically acceptable salt thereof.