Patent ID: 7972862
Filing Date: 2011-07-05
Classification: A61B,Y10T

Abstract:
1. A method of determining glucose concentrations in bodily fluids, comprising: providing a sensing solution comprising a plurality of metal ions; introducing a bodily fluid sample from a subject into said sensing solution, wherein if glucose is present in said bodily fluid sample said glucose reduces said plurality of metal ions to form metal nanoparticles or increases a size of metal nanoparticle seeds if said metal nanoparticle seeds are also provided in said sensing solution; directing incident light at said sensing solution after said introducing; measuring at least one optically-based parameter responsive to said directing of said incident light, and determining a concentration of said glucose in said bodily fluid sample based on an amplitude of said optically-based parameter wherein a higher absorbance corresponds to a higher glucose concentration or a magnitude of a red wavelength shift of a peak absorption wavelength when said metal nanoparticle seeds are provided in said sensing solution and said optically-based parameter is wavelength, wherein a higher red wavelength shift corresponds to a higher glucose concentration.