Patent ID: 8728379
Filing Date: 2014-05-20
Classification: A61L,B29C,C08J,C08K,C08L,Y10T

Abstract:
1. A method of making a cross-linked and interlocked hybrid material for a medical device or implant, wherein the method comprising the steps of: a) mixing a polymeric material with an antioxidant to form a polymeric blend material; b) compression molding the polymeric blend material to the counterface of second material, thereby forming an interlocked hybrid material having an interface between the polymeric blend material and the second material; and c) irradiating the interlocked hybrid material from step (b) with an ionizing radiation dose of between about 50 and about 1000 kGy at an elevated temperature that is above the room temperature and below the melting point of the polymeric blend material by ionizing radiation, thereby forming cross-links in the polymeric blend material and yielding a cross-linked and interlocked hybrid material for a medical device or implant that is resistant to leaching of the antioxidant out of the polymeric blend material, wherein: (i) the cross-linking of the interlocked hybrid material strengthens the polymeric blend material to minimize separation at the interface, (ii) the antioxidant provides resistance to post-irradiation oxidation, and (iii) the irradiation sterilizes the interface.