Patent ID: 6461636
Filing Date: 2002-10-08
Classification: A61K,A61P,Y10S

Abstract:
A transdermal therapeutic system for a transcutaneous administration of pergolide over several days with a means of fixing the system onto skin, wherein the system comprises a matrix mass comprising pergolide and taking a form of a layer, which contains a copolymer consisting essentially of (a) a (meth)acrylate copolymer containing ammonio groups or (b) a mixture of a (meth)acrylate copolymer containing amino groups and a (meth)acrylate polymer containing carboxyl groups, 10 to 50% by weight propylene glycol, and 0.5% to less than 5.0% by weight pergolide or a pharmaceutically acceptable salt thereof calculated as a base, said matrix, with the exception of a releasing area at the point of application, is surrounded by a larger plaster for fixing the matrix to the skin, said plaster being free of pergolide.