Patent ID: 7659053
Filing Date: 2010-02-09
Classification: B01J,B05D,B82Y,G01N,Y10S,Y10T

Abstract:
1. A method for determining mobility of cells comprising: providing a surface having a first portion thereon and a second portion thereon, wherein the first portion is adjacent to the second portion of the surface, wherein the first portion of the surface is associated with a first electrode and the second portion of the surface is associated with a second electrode, wherein said first portion of the surface has molecules directly attached thereon at points of attachment of the molecules to the surface, wherein at least some of the molecules forming the self-assembled monolayer (SAM) on the first portion of the surface comprise a structure: wherein exposing the surface having the first portion and the second portion to the cells, wherein the cells become attached to the first portion of the surface during the exposure; altering the second portion of the surface by detaching at the point of attachment of the SAM forming molecules from the second portion of the surface by exposure of the second portion of the surface to an electric field so as to allow the second portion of the surface to then bind the cells; and determining mobility of the cells by monitoring migration of the cells from the first portion of the surface to the second portion of the surface.