Patent ID: 7235381
Filing Date: 2007-06-26
Classification: C07K,C12N

Abstract:
1. A composition of matter comprising: a) an isolated or purified nucleic acid encoding a signal peptide consisting of residues −28 to −1, inclusive, of SEQ ID NO: 1366 and which signal peptide directs the extracellular secretion of a polypeptide if said signal peptide is operably linked thereto; b) an isolated or purified nucleic acid sequence consisting of nucleotides 115 to 198 of SEQ ID NO: 578; c) a recombinant nucleic acid comprising a heterologous nucleic acid sequence encoding a heterologous polypeptide fused, in frame, to a nucleic acid sequence: i) encoding a signal peptide consisting of residues −28 to −1, inclusive, of SEQ ID NO: 1366 and which signal peptide directs the extracellular secretion of a polypeptide if said signal peptide is operably linked thereto; or ii) encoding a signal peptide comprising residues −28 to −1, inclusive, of SEQ ID NO: 1366 and which signal peptide directs the extracellular secretion of a polypeptide if said signal peptide is operably linked thereto; or iii) consisting of nucleotides 115 to 198 of SEQ ID NO: 578; d) a vector comprising: e) a host cell comprising a vector, said vector comprising: