Patent ID: 8758686
Filing Date: 2014-06-24
Classification: G01J,G01N

Abstract:
1. A device for detecting energy generated by non-radiative decay in an analyte or a complex or derivative of the analyte on irradiation with electromagnetic radiation comprising a radiation source adapted to generate a series of pulses of electromagnetic radiation, a transducer having a pyroelectric or piezoelectric element and electrodes which is capable of transducing the energy generated by the analyte or the complex or derivative of the analyte into an electrical signal, at least one reagent proximal to the transducer, the reagent having a binding site capable of binding the analyte or the complex or derivative of the analyte, a well for holding a liquid having the analyte or the complex or derivative of the analyte dissolved or suspended therein, the liquid being in contact with the transducer, the analyte or the complex or derivative of the analyte dissolved or suspended in the liquid being at a plurality of positions at different distances from the surface of the transducer, and a detector capable of detecting the electrical signal generated by the transducer, wherein the detector is configured to detect only the electrical signal generated by the transducer up to a selected time delay between each pulse of electromagnetic radiation from the radiation source and the generation of the electric signal to distinguish the concentration of the analyte or the complex or derivative of the analyte at different distances from the surface of the transducer.