Patent ID: 8846391
Filing Date: 2014-09-30
Classification: A61P,C07K,C12N,G01N

Abstract:
1. A method of detecting the presence or absence of specific anti-herpes simplex virus type-2 (HSV-2) antibodies in a biological sample, comprising: (a) preabsorbing a biological sample suspected of containing anti-HSV-2 antibodies by contacting the sample with a first preabsorbing antigen comprising the amino acid sequence AAKTPPTTPAP (SEQ ID NO:06), wherein said first preabsorbing antigen is not a full length glycoprotein G2 (gG2) polypeptide and does not deplete said specific anti-HSV-2 antibodies, (b) contacting said biological sample with a second antigen capable of binding a specific anti-HSV-2 antibody, and (c) detecting the presence or absence of specific anti-HSV-2 antibody in said biological sample wherein said specific anti-HSV-2 antibody detected in said sample is bound to said second antigen.