Patent ID: 9121010
Filing Date: 2015-09-01
Classification: C07K,C12N,C12Q,G01N

Abstract:
1. A stably transduced fetal porcine kidney cell line which has been engineered to express a functional bovine α v β 6 integrin receptor, said cell line comprising a host cell transduced with a heterologous nucleic acid molecule comprising a sequence of nucleotides that constitutively express an α v subunit of the bovine α v β 6 integrin receptor and a sequence of nucleotides that constitutively express a β 6 subunit of the bovine α v β 6 integrin receptor, wherein said α v subunit and said β 6 subunit comprise a sequence of nucleotides which encode the bovine α v subunit and the bovine β 6 subunit of the bovine α v β 6 integrin receptor, a functional Foot and Mouth Disease Virus (FMDV) receptor wherein said cell line is the LFBKαvβ6 cell line deposited as ATCC Accession No: PTA-13047.