Patent ID: 7601361
Filing Date: 2009-10-13
Classification: A61K,A61L,C09D

Abstract:
1. A medical device having a durable antimicrobial polymeric surface, said surface comprising a chemically modified polymer substrate selected from the group consisting of polyamides, polyurethanes and polyureas and at least one linear cationic antimicrobial peptide having a net positive charge of greater than 1 at physiological pH, wherein said peptide is selected from the group consisting of: PKGLKKLLKGLKKLLKL (SEQ ID NO: 1); KGLKKLLKGLKKLLKL (SEQ ID NO: 2); KGLKKLLKLLKKLLKL (SEQ ID NO: 3); LKKLLKLLKKLLKL (SEQ ID NO: 4); and LKKLLKLLKKLL (SEQ ID NO: 5);