Patent ID: 7365178
Filing Date: 2008-04-29
Classification: C07H,C12Q

Abstract:
1. A tagged acyl phosphate or phosphonate probe having the formula: wherein X is an affinity moiety for directing the binding of said TAPP to one or more target proteins linked to the phosphate through an oxygen or carbon; TAG is a detectable label; L is an optionally present alkyl or heteroalkyl group of 1-40 backbone atoms selected from the group consisting of —N(R)—, —O—, —S— or —C(R)(R)—, wherein said alkyl or heteroalkyl group optionally includes a carbocyclic or heterocyclic group; each R is independently H or —C the carbonyl adjacent to L is bound to a carbon to form an acyl group; or a pharmaceutically acceptable salt or complex thereof.