Patent ID: 9194775
Filing Date: 2015-11-24
Classification: G01N

Abstract:
1. A method of guided slicing for obtaining histological specimens, comprising steps of: a. extracting a sample from an animal; b. spatially labeling said sample by a fiducial marker; c. acquiring ex vivo images of said sample, d. virtually slicing said image, thereby defining, according to the fiducially marked images, N computer-retrievable three-dimensional image slices [3DISs], N is an integer greater than or equal to 2; e. preparing a slicing program of suspected computer-retrievable three-dimensional image slices (SISs) from said N 3DISs; and f. physically slicing said sample according to said SISs; wherein said step of preparing a slicing program comprises a step of defining from said N 3DISs one or more first SISs and one or more second SISs, wherein the slicing plane of said first SISs and the slicing plane of said second SISs are oriented in a non-parallel manner.