Patent ID: 6080750
Filing Date: 2000-06-27
Classification: A61P,C07D

Abstract:
A pyrimidine compound of the formula (I) ##STR140## wherein R1 is H, C.sub.1 -C.sub.4 alkyl, halogen atom, --OH, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.6 hydroxyalkoxy or --NH.sub.2 ;R2 is --NH.sub.2 or --NHCOCH.sub.3 ;R3 is --NR5(CH.sub.2).sub.i --CH.sub.2 OH;R4 is H, halogen atom, --NH.sub.2, --CN, --CHO, --CH.sub.2 OH, --COOH, --CH.sub.2 NH.sub.2, --CONH.sub.2 or --CH.dbd.N--A, wherein A is --OH, C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy;R5 is H; andi is an integer of 1 to 4,or a pharmacologically acceptable salt thereof.