Patent ID: 8034378
Filing Date: 2011-10-11
Classification: A61K,A61P,C12N

Abstract:
1. An immunogenic composition comprising: (a) a polymer microparticle comprising a polymer selected from a poly(α-hydroxy acid), a polyhydroxy butyric acid, a polycaprolactone, a polyorthoester, a polyanhydride, and a polycyanoacrylate; (b) an antigen adsorbed to the microparticle; and (c) a synthetic phospholipid compound comprising: (i) one or more phosphoryl groups independently selected from a group and a group; and (ii) a plurality of linear alkane groups, in which n is independently an integer ranging from 6 to 20, or a pharmaceutically acceptable salt thereof, wherein composition provides an antibody mediated immune response that is greater than that observed in the absence of said synthetic phospholipid compound.