Patent ID: 8211475
Filing Date: 2012-07-03
Classification: A61K

Abstract:
1. A method for preparing chitosan nanoparticles in an aqueous solution consisting of the following steps: (a) providing a chitosan solution having a concentration of about 0.05 w/v % to about 1 w/v %, wherein the chitosan solution is formed by dissolving chitosan in a solvent, and the solvent is an aqueous solution selected from acetic acid, formic acid, propanoic acid, malic acid, succinic acid and lactic acid; (b) adding water followed by acetic anhydride to the chitosan solution to carry out acetylation, wherein the concentration of acetic anhydride is about 10 v/v % to about 30 v/v % of the total volume of the whole solution; and (c) subjecting the solution from step (b) to physical dispersion.