Patent ID: 7172865
Filing Date: 2007-02-06
Classification: G01N,Y10S

Abstract:
1. A biosensor assay useful for determining the activity of a nucleic acid binding protein coregulator comprising a first nucleic acid component, a second nucleic acid component and a nucleic acid binding factor, wherein (a) the first nucleic acid component comprises a portion of a nucleic acid binding element and the second nucleic acid component comprises a portion of the same a nucleic acid binding element, wherein the combination of both the first and second nucleic acid components comprises the nucleic acid binding element; and (b) a detectable label is attached to the first nucleic acid component, the second nucleic acid component, or the nucleic acid binding factor, wherein the label is detected upon binding of the nucleic acid binding factor to the first and second nucleic acid components, to form a nucleic acid binding element, said binding being enhanced or disrupted by the nucleic acid binding protein coregulator.