Patent ID: 8835682
Filing Date: 2014-09-16
Classification: A61P,C07C,C07D

Abstract:
1. A process for preparing a compound of formula (I): wherein: R1 is H or a group selected from the group consisting of (C R2 is a group selected from the group consisting of (C R3 is H or a group selected from the group consisting of (C R6 represents a group of formula (i) or (ii) or (iii) or (iv): wherein * indicates the position at which R6 is bonded to formula (I); m=1, 2, or 3; n=1, 2, or 3; A R4 is a group of formula (Y) wherein p is 0 or an integer from 1 to 4; q is 0 or an integer from 1 to 4; P is absent or is selected from the group consisting of O, S, SO, SO W is H or a group selected from the group consisting of (C R5 is H or a group selected from the group consisting of (C or a pharmaceutically acceptable salt thereof, with the proviso that when R1 is H, R2 is phenyl, and R3 is H, then R6 is not a group of formula (iii), said process comprising: alkylating a compound of formula (VI): with an alkylating agent of formula (XI): wherein A is a suitable leaving group selected from the group consisting of halide and sulfonate, and R7 represents a group of formula (vi) or (vii) or (viii) or (ix): wherein * indicates the position at which R7 is bonded to formula (VI); m=1, 2, or 3; n=1, 2, or 3.