Patent ID: 7452685
Filing Date: 2008-11-18
Classification: C07K

Abstract:
1. A method for identifying a compound that putatively modulates or elicits taste in a human subject comprising: (1) screening one or more compounds in a binding assay which identifies compounds that specifically bind to a human T1R1 polypeptide or which modulate (inhibit or enhance) the specific binding of another compound that specifically binds to said human T1R1 polypeptide, wherein said T1R1 polypeptide is selected from the group consisting of: (2) identifying compounds that putatively modulate taste based on its specific binding to a human T1R1 polypeptide according to (a), (b), or (c), or its modulation (inhibition or enhancement) of the specific binding of another compound to a T1R1 polypeptide according to (a), (b), or (c).