Patent ID: 7662403
Filing Date: 2010-02-16
Classification: A61K,A61P,Y10S

Abstract:
1. A powder formulation for intranasal delivery consisting essentially of a protein having a molecular weight of 10 kDa or greater; chitosan glutamate in an amount of 30 to 65% by weight based on the total weight of the formulation; and optionally one or more additional water-soluble, non-gel forming ingredients, wherein the protein is in the form of a protein powder having a mean particle size, expressed as the volume mean diameter (D 50 % ), of about 25 to 200 μm, and the chitosan glutamate is in the form of a powder having a mean particle size, expressed as the volume mean diameter (D 50% ), of about 25 to 200 μm and has a solubility in water of at least 10 mg/ml at room temperature and atmospheric pressure.