Patent ID: 8586038
Filing Date: 2013-11-19
Classification: A61K,A61P,C07K,C12N

Abstract:
1. A polypeptide represented by the following formula: wherein: N′ is the N-terminus and C′ is the C-terminus of the polypeptide, Y is an amino acid sequence consisting of 5 or more consecutive amino acid residues from e C-terminus at positions 99 to 162 of SEQ ID NO: 14; Z2 is an amino acid sequence consisting of four or more consecutive amino residues from the N-terminus at positions 163 to 199 of SEQ ID NO: 14; Z3 is an amino acid sequence consisting of seventy , one or more consecutive amino acid residues from the C-terminus at positions 115 to 220 of SEQ ID NO: 13; Z4 is an amino acid sequence consisting of eighty or more consecutive amino acid residues from the N-terminus at positions 221 to 327 of SEQ ID NO: 13; and Z1 is an amino acid sequence consisting of five or more consecutive amino acid residues from the C-terminus at positions 90 to 98 of SEQ ID NO: 11 or five or more consecutive amino acid residues from the C-terminus at positions 90 to 98 of SEQ ID NO: 14 and p is an integer of 0 or 1, wherein the total number of the amino acid residues for Z2 and Z3 is between 80 and 140, both inclusive; and wherein the total number of the amino acid residues for the polypeptide is between 154 and 288, both inclusive.