Patent ID: 6706718
Filing Date: 2004-03-16
Classification: A61P,C07D

Abstract:
A novel compound of formula (I): or stereoisomers thereof, N-Oxides thereof, pharmaceutically acceptable salts thereof, and prodrugs thereof, wherein: R is independently at each occurrence selected from the group: H, NR1R2, NR1C(O)R3, NR1C(O)OR5, NHC(O)NR1R2, NHC(S)NR1R2, and 5-10 membered heterocycle containing from 1-4 heteroatoms selected from O, N, and S, wherein the heterocycle is substituted with 0-4 R4 substituents;R1 is selected from the group: H, halo, â€”CN, C1-4 haloalkyl, C1-4 alkyl, phenyl, and benzyl; R2 is selected from the group: H, C1-4 alkyl, phenyl, and benzyl; alternatively, R1 and R2, together with the nitrogen atom to which they are attached, form a 4-8 membered heterocyclic group or a 4-8 membered heterocyclenyl group containing an additional 0-1 N, S, or O atom, wherein the heterocyclic or heterocyclenyl group is substituted with 0-4 R4 substituents; R3 is selected from the group: H, halo, â€”CN, C1-4 haloalkyl, C1-4 alkyl, phenyl, and benzyl; and R4 is selected from the group: halo, â€”CN, C1-4 haloalkyl, C1-4 alkyl, phenyl, and benzyl; R5 is selected from the group: H, C1-4 alkyl, phenyl, and benzyl.