Patent ID: 6107317
Filing Date: 2000-08-22
Classification: C07D

Abstract:
A compound of formula I: ##STR12## wherein R is a group ##STR13## an unsubstituted (C.sub.3-7)cycloalkyl ring; a (C.sub.3-7)cycloalkyl ring substituted in the 1-position by a hydroxy(C.sub.1-3)alkyl group; a group .paren open-st.CH.sub.2 .paren close-st..sub.2 R.sub.2 ; a group ##STR14## a group .paren open-st.CH.sub.2 .paren close-st..sub.3 R.sub.4 ; an isopropyl group; or an isopropyl group substituted in the 1-position by a hydroxy-(C.sub.1-3)alkyl group;R.sub.1 is an unsubstituted pyridine ring; a pyridine ring mono- or di-substituted by halo, trifluoromethyl or cyano; an unsubstituted pyrirmidine ring; or a pyrimidine ring monosubstituted by halo, trifluoromethyl or cyano;R.sub.2 is an unsubstituted phenyl ring; or a phenyl ring mono-, di- or tri-substituted by halo or (C.sub.1-3)alkoxy;eachR.sub.3, independently, is an unsubstituted phenyl ring; or a phenyl ring monosubstituted by halo or (C.sub.1-3)alkoxy; andR.sub.4 is a 2-oxopyrrolidine group or a (C.sub.2-4)alkoxy group; or a pharmaceutically acceptable acid addition salt thereof.