Patent ID: 7846675
Filing Date: 2010-12-07
Classification: A61K,C07K,Y02A

Abstract:
1. An assay for detecting antibody to scrub typhus comprising: a) Obtaining a sample from a subject; and b) Exposing the sample to a combination of isolated polypeptides, having amino acids sequences set forth in SEQ ID NO.:1 and SEQ ID NO.: 4 or set forth in SEQ ID NO.:1 and SEQ ID No.: 5, said polypeptides being the refolded expressed product of truncated non-fusion r56 genes from c) Incubating said sample, wherein said antibody binds said combination of isolated polypeptides forming a complex; d) Binding a detectable label to said complex wherein a detectable signal is produced; e) Detecting the signal, wherein the signal indicates the presence of said antibody.