Patent ID: 9220631
Filing Date: 2015-12-29
Classification: A61F,A61K,A61M,A61P

Abstract:
1. A pre-filled, terminally sterilized syringe for intravitreal injection, the syringe comprising a glass body forming a barrel, a stopper and a plunger and containing an ophthalmic solution which comprises a VEGF-antagonist, wherein: (a) the syringe has a nominal maximum fill volume of between about 0.5 ml and about 1 ml, (b) the syringe barrel comprises from about 1 μg to 100 ug silicone oil, (c) the VEGF antagonist solution comprises no more than 2 particles >50 μm in diameter per ml and wherein the syringe has a stopper break loose force of less than about 11N.