Patent ID: 6642387
Filing Date: 2003-11-04
Classification: C07D

Abstract:
A method of producing a substituted acetylpyridine represented by the formula (12): in the formula, X represents a hydrogen, a halogen, a hydroxyl group, an acyloxy group containing 1 to 10 carbon atoms, an alkoxy group containing 1 to 10 carbon atoms, an amino group or a substituted amino group and R6 represents an alkyl group containing 1 to 15 carbon atoms, an aralkyl group containing 1 to 15 carbon atoms or an aryl group containing 6 to 16 carbon atoms, which comprises reacting a substituted acetylpytidine represented by the formula (7) the formula, X is as defined above and Y2 represents a halogen,with a carboxylic acid represented by the formula (11): in the formula, R6 is as defined above,in the presence of a base and a quaternary ammonium salt.