Patent ID: 9040241
Filing Date: 2015-05-26
Classification: A61K,C12Q,G16B,G16H,Y02A

Abstract:
1. A method of treating a human subject having schizophrenia (SZ), the method comprising: selecting a human subject having SZ; performing an assay to determine an ankyrin-3 (ANK3) haplotype for the selected subject, wherein the ANK3 haplotype comprises an allele of single nucleotide polymorphism rs1551213; identifying a selected subject having a T allele at rs1551213 as more likely to have a negative side effect in response to risperidone compared to a subject not having a T allele at rs1551213, or identifying a selected subject not having a T allele at rs1551213 as less likely to have a negative side effect in response to risperidone compared to a subject having a T allele at rs1551213; and administering a treatment not comprising risperidone to a selected subject identified as having an T allele at rs1551213 or administering a treatment comprising risperidone to a selected subject identified as not having a T allele at rs1551213.