Patent ID: 8097632
Filing Date: 2012-01-17
Classification: A61K,A61P

Abstract:
1. A method of therapeutically treating cancer in a patient diagnosed with cancer, wherein the cancer is basal cell carcinoma, medulloblastoma, squamous cell carcinoma, carcinosarcoma, adenocystic carcinoma, epidermoid carcinoma, nasopharyngeal carcinoma, renal cell carcinoma, a papilloma, an epidermoidoma, a glioma, meningioma, a neuroectodermal tumor, an ependymoma, pineoblastoma, hemangioma, pancreatic cancer, adenocarcinoma, rhabdomyosarcoma, glioblastoma, sarcoma, thyroid carcinoma, bone cancer, lung cancer, chondrosarcoma, breast cancer, urogenital cancer, kidney cancer, bladder cancer, ureter cancer, prostate cancer, adrenal cancer, gastrointestinal cancer, stomach cancer, intestinal cancer, keratoacanthoma, or malignant hepatoma, comprising administering to the patient a steroidal alkaloid represented in general Formula II or a homo-derivative thereof: wherein, as valence and stability permit, R R R with the proviso that at least one of R R m is an integer in the range 0 to 8 inclusive; wherein the bonds with a dotted line optionally and independently represent a single or double bond, and wherein R or a salt thereof.