Patent ID: 6569831
Filing Date: 2003-05-27
Classification: A61P,C07K,C12N

Abstract:
A method for producing mature lactoferrin, the method comprising:(i) providing a recombinant vector comprising a nucleic acid molecule: (a) encoding a mature lactoferrin or a lactoferrin-derived protein that maintains antibacterial, antifungal, antiviral, anti-inflammatory, anti-oxidant, iron-binding, or Jurkat cell or enterocyte HT29 cell binding, and (b) a promoter and a transcription terminator which are operatively linked to a nucleic acid encoding the protein of (a) and are recognized by the transcriptional machinery of plante-cells; (ii) transforming a monocotyledon plant cell with said recombinant vector; (iii) expressing mature lactoferrin or lactoferrin-derived protein from said monocotyledon plant cell, or from a plant produced from said monocotyledon plant cell; and (iv) isolating mature lactoferrin or lactoferrin-derived protein from said monocotyledon plant cell, or from a plant produced from said monocotyledon plant cell.