Patent ID: 6080874
Filing Date: 2000-06-27
Classification: C07D

Abstract:
A process for preparing an aryl substituted N-hydroxyurea having the structure: ##STR21## comprising mixing a compound of formula: ##STR22## with hydroxyurea and acid; wherein R is selected from the group consisting of substituted or unsubstituted aryl and heteroaryl;R.sup.2 is selected from the group consisting of 1-6 carbon alkyl, aryl and 3-6 carbon cycloalkyl that is independent or fused with R;R.sup.3 is selected from the group consisting of hydrogen, aralkyl, aryl, 1-6 carbon alkyl, 1-6 carbon alkylcarbonyl, and arylcarbonyl; andR.sup.4 is selected from the group consisting of hydrogen, aralkyl, aryl, 1-6 carbon alkyl, 1-6 carbon alkylcarbonyl, and arylcarbonyl.