Patent ID: 6703402
Filing Date: 2004-03-09
Classification: A61P,C07D

Abstract:
A method of inducing cytokine biosynthesis in a mammal comprising administering a composition comprising a therapeutically effective amount of a compound of the formula I: wherein:R1 is selected from the group consisting of oxygen, sulfur and selenium; R2 is selected from the group consisting of -hydrogen; -alkyl; -alkyl-OH; -haloalkyl; -alkenyl; -alkyl-X-alkyl; -alkyl-X-alkenyl; -alkenyl-X-alkyl; -alkenyl-X-alkenyl; -alkyl-N(R5)2; -alkyl-N3; -alkyl-Oâ€”C(O)â€”N(R5)2; -ayl-aryl; -alkyl-X-aryl; and -alkenyl-X-aryl; R3 and R4 are taken together to form a fused aromatic ring; X is selected from the group consisting of â€”Oâ€”, â€”Sâ€”, â€”NR5â€”, â€”C(O)â€”, â€”C(O)Oâ€”, â€”OC(O)â€”, and a bond; and each R5 is independently H or C1-8alkyl; or a pharmaceutically acceptable salt thereof, with a pharmaceutically acceptable carrier, to the mammal.