Patent ID: 6372711
Filing Date: 2002-04-16
Classification: A61K,A61P,C07K,Y10S

Abstract:
In a method of assaying human FSH using a molecule which binds human FSH, the improvement wherein said molecule is a polypeptide capable of binding FSH which includes a contiguous portion of the extracellular domain of the human FSH receptor, said domain having the sequence of amino acids 1-349 of SEQ ID NO:2, which portion retains substantially the same FSH-binding characteristics as the complete extracellular domain, or a polypeptide which includes a mutein of said portion, the sequence of said mutein differing from the sequence of said portion by substitutions, deletions or insertions affecting a total of no more than ten amino acids, and which mutein retains substantially the same FSH-binding characteristic as said portion.