Patent ID: 6352989
Filing Date: 2002-03-05
Classification: A61P,C07D

Abstract:
A nitrogen-containing heterocyclic compound represented by the following formula, its salt or hydrates thereof wherein the ring A is an aromatic hydrocarbon ring which may have a heteroatom,the ring B represents:1) a saturated hydrocarbon ring which may have a substituent group, 2) an unsaturated hydrocarbon ring which may have a substituent group, 3) a saturated heterocyclic ring which may have a substituent group or 4) an unsaturated heterocyclic ring which may have a substituent group, R1 represents:1) hydrogen atom, 2) a halogen atom, 3) a C1-6 alkyl group which may be substituted with a halogen atom, 4) a C1-6 alkoxy group which may be substituted with a halogen atom or 5) an amino group which may be substituted with a C1-6 alkyl group or an acyl group, R2 and R3 are the same as or different from and represent:1) hydrogen atom, 2) a C1-6 alkyl group which may have a substituent group, 3) a C3-7 cycloalkyl group which may have a substituent group, 4) a C2-6 alkenyl group which may have a substituent group or 5) an acyl group, R4, R5, R6 and R7 are the same as or different from and represent:1) hydrogen atom, 2) a halogen atom, 3) a C1-6 alkyl group which may be substituted with a halogen atom, 4) a C3-7 cycloalkyl group which may have a substituent group, 5) an aryl group which may have a substituent group, 6) a C1-6 alkoxy group which may have a substituent group, 7) a C3-7 cycloalkoxy group which may have a substituent group, 8) an aryl alkoxy group which may have a substituent group or 9) a C1-6 alkyl thio group which may have a substituent group, 10) a hydroxyl group, 11) an amino group which may be substituted with a C1-6 alkyl group or an acyl group, 12) a nitro group, 13) a cyano group, 14) a carboxyl group or 15) a C1-6 alkoxy carbonyl group, L represents: 1) a single bond, 2) a C1-6 alkylene group which may have a substituent group, 3) a C2-6 alkenylene group which may have a substituent group, 4) a C2-6 alkynylene group which may have a substituent group or 5) a group represented by the formula â€”Eâ€”Gâ€” (wherein E represents: a) an oxygen atom, b) a sulfur atom, c) formula â€”COâ€”, d) â€”SOâ€”, e) â€”SO2â€”, f) â€”N(R8)â€” (wherein R8 represents hydrogen atom, a C1-6 alkyl group or an acyl group), g) â€”N(R9)â€”COâ€” (wherein R9 represents hydrogen atom or a C1-6 alkyl group) or h) â€”(CH2)mâ€” (wherein m is an integer of 0 to 6) which may have a substituent group, and G represents: a) a sulfonyl group, b) formula â€”N(R10)â€” (wherein R10 represents hydrogen atom, a C1-6 alkyl group or an acyl group) or c) â€”(CH2)nâ€” (wherein n is an integer of 0 to 6)) and X and Y both represent nitrogen atoms.