Patent ID: 8992979
Filing Date: 2015-03-31
Classification: A61K,A61L,A61P

Abstract:
1. A medical device comprising: a substrate and a biocompatible coating deposited on at least a fraction of said substrate, wherein the biocompatible coating comprises a non-liposomal matrix composition, the matrix composition comprising: (a) a biocompatible non-biodegradable polymer non-covalently associated with a first lipid comprising at least one sterol having a polar group; (b) a second lipid comprising at least one phospholipid having hydrocarbon chains of at least 14 carbons, wherein the biocompatible non-biodegradable polymer is not bonded to the second lipid; and (c) at least one pharmaceutically active agent; wherein the matrix composition is lipid saturated and when maintained in an aqueous environment provides zero-order release of least 40% the pharmaceutically active agent.