Patent ID: 8071626
Filing Date: 2011-12-06
Classification: C07D,C07F,G01N

Abstract:
1. A chelating agent comprising (a) two or more pyridyl groups, wherein at least one of said two or more pyridyl groups is substituted with a trialkoxyphenyl group, wherein the alkoxy groups are same or different C1-C4 alkoxy groups, carboxyalkoxy groups or alkoxycarbonylalkoxy groups, and the pyridyl groups are i) tethered directly to each other to form a 2,2″-bipyridyl or 2,2″:6″,2″-terpyridyl group, respectively, or ii) tethered to each other via N-containing hydrocarbon chains; (b) at least two carboxylic acid or phosphonic acid groups, or esters or salts of said acid groups, attached to the pyridyl groups at ortho position either directly or via an N-containing hydrocarbon chain; and (c) a substituent A selected from the group consisting of isothiocyanate, haloacetamido, maleimido, dichlorotriazinylamino, pyridyldithio, thioester, aminooxy, hydrazide, amino, a polymerizing group, a carboxylic acid or acid halide or an active ester thereof, an amino acid residue —CH(NHR said substituent A is tethered to i) at least one of said two or more pyridyl groups, or ii) at least one of said hydrocarbon chains, either directly or via a linker x, wherein said linker x is formed from one to ten moieties, each moiety being selected from the group consisting of phenylene, alkylene containing 1-12 carbon atoms, ethynydiyl (—C≡C—), ethylenediyl (—C═C—), ether (—O—), thioether (—S—) amide (—CO—NH—, —CO—NR″—, NH—CO and —NR′'CO—), carbonyl (—CO—), ester (—COO— and —OOC—), disulfide (—SS—), diaza (—N═N—), and tertiary amine, wherein R′ represents an alkyl group containing less than 5 carbon atoms.