Patent ID: 7632808
Filing Date: 2009-12-15
Classification: A61K,A61P,C07K

Abstract:
1. A method for stimulating the outgrowth of nerve fibers from the retina in a patient with an injury to the neuronal layer of the retina, the method comprising administering to the patient an effective amount of biologically active MP52 selected from the group consisting of (a) the mature part of the protein sequence shown in SEQ ID NO: 1; (b) parts of the mature protein which have essentially the same survival promoting effect on dopaminergic neurons as the mature part of the protein sequence shown in SEQ ID NO: 1; and (c) the mature part of the protein sequence shown in SEQ ID NO: 1 wherein the N-terminus is modified by the addition of a methionine residue and/or a histidine tag.