Patent ID: 8741325
Filing Date: 2014-06-03
Classification: A01N

Abstract:
1. A material in the form of liquid for forming an antimicrobial surface coating with multi-level antimicrobial properties upon application on an article or subject, which comprises: (i) a water-in-oil-in-water (w/o/w) double emulsion having a first water phase and a second water phase, comprising a) two or more amphiphilic block copolymers with different hydrophilic lipophilic balances (HLBs) for forming the w/o/w double emulsion, and b) one or more volatile or gaseous biocides which are present in the first water phase and encapsulated in said two or more amphiphilic block copolymers; and (ii) one or more nonvolatile biocides, each of which is selected from the group consisting of a metal containing biocide, triclosan, a carboxylic acid, a sugar acid and a combination thereof, wherein the coating as formed by the material exhibits multi-level antimicrobial properties including release-killing, contact-killing and anti-adhesion effects through (1) a sustained release of the volatile biocides to disinfect and inhibit microbial growth, (2) an increased release of the biocide(s) on contact with infectious droplets, and (3) a nanostructure of the nonvolatile biocide(s) as formed on surfaces to inactivate and prevent the adhesion of microorganisms when applied.