Patent ID: 7781464
Filing Date: 2010-08-24
Classification: A61P,C07D

Abstract:
1. A compound of the formula (I) and tautomeric forms, stereoisomers, and pharmaceutically acceptable salts thereof, wherein ---- represents an optional bond; V represents CH or N; Y represents O or S; W represents O or NR 8 ; R 8 is selected from hydrogen or linear, branched, substituted or unsubstituted (C 1 -C 6 ) alkyl groups; X represents CR 9 , O or S wherein R 9 is hydrogen or R 9 together with Z forms a 5 or 6-membered aromatic or heteroaromatic ring system containing 1 to 2 heteroatoms selected from O, S or N; Z represents O, S or together with R 9 forms a 5 to 6 membered aromatic or heteroaromatic ring system containing 1 to 2 hetero atoms selected from O, S or N; R 1 and R 2 may be same or different and are independently selected from hydrogen, a halogen, hydroxy, nitro, cyano, formyl, COR 10 or linear or branched (C 1 -C 6 ) alkyl group; or substituted or unsubstituted (C 1 -C 6 ) alkoxy group; with the proviso that when one of R 1 and R 2 is hydrogen, the other is COR 10 ; R 10 represents —OR 11 or NR 12 R 13 ; where R 11 represents hydrogen, a substituted or unsubstituted group selected from alkyl, alkenyl, aryl, aralkyl, heteroaryl, or a counter ion; R 12 and R 13 may be same or different and independently represent H or substituted or unsubstituted alkyl, alkenyl or aryl groups; or R 12 and R 13 together form a heteroaliphatic or heteroaromatic ring; R 3 , R 4 , R 5 and R 6 , are selected from hydrogen, halogen; hydroxy, nitro, cyano, formyl, amino, linear or branched, substituted or unsubstituted (C 1 -C 6 ) alkyl or alkoxy groups; haloalkyl groups, carboxylic acid and its esters and amides; unsubstituted sulfonamide, sulfonyl methyl group; R 7 represents hydrogen, substituted or unsubstituted alkyl, alkenyl, —CH 2 COOR, aryl groups, or a counter ion; where R represents H or (C 1 -C 6 ) alkyl group.