Patent ID: 7786077
Filing Date: 2010-08-31
Classification: A61K,A61P

Abstract:
1. A pharmaceutical combination comprising (a) a therapeutic effective amount of an insulin compound selected from the group consisting of insulin, insulin analogues and mixtures thereof, and (b) a therapeutic effective amount of a pharmaceutically acceptable betaine of general formula (CH 3 ) 3 N + —(CH 2 )n —COO − ; with n being an integer from 1 to 5, in which the insulin and the betaine form at least partly a structure selected from the group consisting of chemical entity, chemical complex, physico complex, insulin/betaine micelles, insulin/betaine microstructures, insulin/betaine nanostructures, and combinations thereof, and in which the weight ratio of therapeutic effective amount of the insulin compound/therapeutic effective amount of betaine is between 1:400 and 1:5.