Patent ID: 8962022
Filing Date: 2015-02-24
Classification: A61K,A61P

Abstract:
1. An orally disintegrating composition comprising: a. taste-masked microparticles, each comprising: b. rapidly dispersing microgranules each comprising: wherein after administration said disintegrating composition substantially disintegrates in the oral cavity of a patient, wherein said taste-masking layer substantially masks the taste of the substituted benzhydrylpiperazine acceptable salt, ester, and/or solvate thereof, and wherein said orally disintegrating composition releases not less than 75% of said substituted benzhydrylpiperazine or a pharmaceutically acceptable salt, ester, solvate, and/or combination thereof within 15 minutes when dissolution tested using United States Pharmacopeia Apparatus 1 (baskets @ 100 rpm) or Apparatus 2 (paddles @50 rpm) in 900 mL of 0.1N HCl.