Patent ID: 8178557
Filing Date: 2012-05-15
Classification: A61P,C07D

Abstract:
1. A method of treating cancer in a subject, said method comprising administering an effective amount of a compound of Formula I′ wherein R is selected from wherein R wherein ring T is selected from phenyl and 5-6-membered heteroaryl; wherein Z is selected from N or CR wherein A is wherein X is selected from O, S, NR wherein Y is selected from —NR wherein R wherein R wherein R wherein R wherein R wherein R wherein R wherein R wherein p is 0, 1, 2, or 3; and wherein t is 0, 1 or 2; wherein each alkyl, aryl, heteroaryl, cycloalkyl, alkenyl, alkynyl, heterocyclyl, and alkoxy moiety of any R, R and pharmaceutically acceptable derivatives thereof;