Patent ID: 6627222
Filing Date: 2003-09-30
Classification: A61K

Abstract:
A once-a-day antibiotic product comprising: first, second, and third dosage forms, wherein each of said dosage forms includes at least one antibiotic and a pharmaceutically acceptable carrier; one of said dosage forms includes at least a first antibiotic and another of said dosage forms includes at least a second antibiotic that is different from the first antibiotic; wherein said first and second antibiotics are each selected from the group consisting of Amoxicillin and Dicloxacillin; and wherein when said first antibiotic is Amoxicillin said second antibiotic is Dicloxacillin; and wherein when said first antibiotic is Dicloxacillin said second antibiotic is Amoxicillin; said first dosage form is an immediate release dosage form; said second and third dosage forms are delayed release dosage forms; each of said first, second, and third dosage forms initiates release of antibiotic at different times and Cmax in serum of the total antibiotic released from said antibiotic product is achieved in less than about 12 hours from administration; and said once-a-day antibiotic product contains the total dosage of said first and second antibiotics for a twenty-four hour period.