Patent ID: 6194565
Filing Date: 2001-02-27
Classification: A61P,C07J

Abstract:
A compound of the formula ##STR13##wherein the A and B rings represent a group ##STR14##wherein the ketone function in position 3 is optionally protected in the form of a ketal, thioketal, hemithioketal or enol ether or ##STR15##wherein R is methyl or --CH.sub.2 --OR', R' is hydrogen or a protecting ether or ester group and R.sub.1 and R.sub.2 form together a second bond,or R.sub.1, and R.sub.2 form together .beta.-epoxide, or R.sub.1 is hydrogen, ketone or hydroxy in .alpha.- or .beta.-position, free or protected in the form of an ether or ester and R.sub.2 is .alpha.-hydroxy, or R.sub.1 is .beta.-hydroxy, free or protected in the form of an ether or ester and R.sub.2 is a .alpha.-fluorine or .alpha.-bromine, and R.sub.3 is hydrogen, fluorine, .alpha.-methyl or .beta.-methyl.