Patent ID: 7410759
Filing Date: 2008-08-12
Classification: A61P,C12Q

Abstract:
1. A method for determining the likelihood that a human subject has major depression disorder, the method comprising the steps of: (i) isolating a subject's brain tissue, wherein the brain tissue is dorsolateral prefrontal cortex tissue; (ii) contacting the subject's isolated brain tissue with a nucleic acid probe which is at least 95% complementary to SEQ ID NO:1; (iii) detecting the level of probe that associates with said subject's FGFR2 mRNA; and (iv) comparing the detected level of associated probe with a control, whereby if the detected level is less than the control, an increased likelihood that the subject has major depression disorder is determined; and whereby, if the detected level is not less than the control, an increase in said likelihood is not determined by the method.