Patent ID: 6750026
Filing Date: 2004-06-15
Classification: A61K,A61P,C07K

Abstract:
A method for identifying a compound as an agonist or antagonist of the interaction between SEQ ID NO: 3 with the human HFGAN72 receptor, said method comprising the steps of:(a) in the presence of a labeled or unlabeled SEQ ID NO: 3, contacting a cell expressing on the surface thereof said human HFGAN72 receptor with said compound, said cell may be-associated with a second component capable of providing a detectable signal in response to the binding of SEQ ID NO: 3 to said receptor compared with cells' expressing on the surface thereof fewer or no human HFGAN72 receptors; and (b) determining whether said compound activates or inhibits said signal, wherein a compound that activates said signal is an agonist and a compound that inhibits said signal is an antagonist.