Patent ID: 9034324
Filing Date: 2015-05-19
Classification: A61K,A61P,C07K

Abstract:
1. An isolated antibody or antigen binding fragment thereof that binds to the polypeptide of SEQ ID NO:9, wherein the antibody or antigen binding fragment thereof comprises: a) a variable domain comprising CDR1, CDR2, and CDR3 of the amino acid sequence of SEQ ID NO:1 and a variable domain comprising CDR1, CDR2, and CDR3 of the amino acid sequence of SEQ ID NO:2; b) a variable domain comprising CDR1, CDR2, and CDR3 of the amino acid sequence of SEQ ID NO:3 and a variable domain comprising CDR1, CDR2, and CDR3 of the amino acid sequence of SEQ ID NO:4, SEQ ID NO:11, or SEQ ID NO:12; c) a variable domain comprising CDR1, CDR2, and CDR3 of the amino acid sequence of SEQ ID NO:5 and a variable domain comprising CDR1, CDR2, and CDR3 of the amino acid sequence of SEQ ID NO:6; or d) a variable domain comprising CDR1, CDR2, and CDR3 of the amino acid sequence of SEQ ID NO:7 and a variable domain comprising CDR1, CDR2, and CDR3 of the amino acid sequence of SEQ ID NO:8.