Patent ID: 8043826
Filing Date: 2011-10-25
Classification: C12Q,G01N

Abstract:
1. A device for monitoring cyclooxygenase-1 (COX1) -inhibitor response comprising: a predetermined volume of a solution of light-producing ATP-consuming enzyme; a predetermined volume of a solution of COX1-dependent platelet agonist; a fluid-tight material forming an assay chamber; a pump functionally linked to the assay chamber for pumping fluids into the assay chamber; a light detector functionally linked to the assay chamber for detecting light emitted in the assay chamber; a fluid-tight material forming a blood chamber for holding blood, the blood chamber functionally linked to the pump; a fluid-tight material forming an enzyme chamber for holding the predetermined volume of the solution of the light-producing ATP-consuming enzyme, the enzyme chamber functionally linked to the pump; and a fluid-tight material forming an agonist chamber for holding the predetermined volume of the solution of the COX1-dependent platelet agonist, the agonist chamber functionally linked to the pump.