Patent ID: 6395308
Filing Date: 2002-05-28
Classification: A61K,A61P

Abstract:
A purified plant extract, said plant being Harpagophytum procumbens and/or Harpagophytum zeyheri DENCE, obtainable by the process comprising the steps of:a) preparing an aqueous extract or an aqueous/C1-C3 alcoholic extract of a dried root of said plant; b) drying said extract to obtain a dried extract; c) dissolving said dried extract in water saturated with n-butanol to obtain a solution; d) subjecting the solution to liquid/liquid extraction with n-butanol saturated with water to obtain an n-butanol phase and an aqueous phase as a two-phase mixture; and e) removing the n-butanol from the two-phase mixture, in vacuo, to obtain a dry extract having a harpagoside content of about 15-30%, as determined by HPLC, as said purified plant extract.