Patent ID: 7521250
Filing Date: 2009-04-21
Classification: C07D,C07F,C09K,G01N

Abstract:
1. A method comprising: in an aqueous solution, providing a fluorescent sensor for phosphate ion and phosphorylated peptide, which sensor comprises a phosphate anion-selective fluorescent compound expressed by the following general formula (1): wherein FL represents a fluorescent functional group or atomic group having an aromatic ring or heterocyclic ring, and X represents a functional group or atomic group which is liberated in an aqueous solution to form an anion; and sensing at least one of phosphate ion and phosphorylated peptide in the aqueous solution as a change in fluorescent intensity, wherein said phosphorylated peptide is composed of an amino acid sequence containing a hydrophobic amino acid and an anionic amino acid in addition to a phosphorylated amino acid.