Patent ID: 8962341
Filing Date: 2015-02-24
Classification: C07K,C12Q,G01N,Y10T

Abstract:
1. A method of screening for interstitial cystitis in a patient, said method comprising the steps of: (a) obtaining a fluid sample from a patient; (b) applying the sample to a detector device, wherein the detector device is a dipstick device, wherein the detector device comprises at least one detection reagent, wherein the detection reagent is a fragment of CKAP4 which comprises a polyhistidine tag at the end of said fragment of CKAP4, and wherein the detection reagent specifically binds antiproliferative factor (APF), further wherein the detection reagent is detectably labeled, wherein the binding of APF to the detection reagent provides detection of a threshold level of APF in the sample in the form of a visual indication that provides correlation with the presence of interstitial cystitis, and wherein the threshold level is above about 10 fMolar; and, (c) visualizing the dipstick device to ascertain a positive screen for interstitial cystitis.