Patent ID: 9034822
Filing Date: 2015-05-19
Classification: A61K,A61P,C07K,G01N

Abstract:
1. A method for reversing the anticoagulant effect of dabigatran or 1-O-acylglucuronide of dabigatran in a patient being treated with dabigatran, dabigatran etexilate, a prodrug of dabigatran or a pharmaceutically acceptable salt thereof, comprising administering an effective amount of an antibody molecule which comprises a heavy chain variable domain with a CDR1 of SEQ ID NO:1, a CDR2 of SEQ ID NO: 7, and a CDR3 of SEQ ID NO: 10, and a light chain variable domain with a CDR1 of SEQ ID NO: 13, a CDR2 of SEQ ID NO: 14, and a CDR3 of SEQ ID NO: 15 to a patient in need thereof.