Patent ID: 8030520
Filing Date: 2011-10-04
Classification: C07B,C07C

Abstract:
1. Process for preparing organic compounds of the general formula (I) where R is a substituted or unsubstituted aromatic radical selected from the group consisting of phenyl, naphtyl, tolyl, anisole, cresol, aniline, and benzoic acid, and R′ is a linear, branched, substituted or unsubstitued C by reacting a corresponding compound of the general formula (II) where X is chlorine, bromine, iodine, diazonium, mesylate (methanesulphonate), tosylate (p-toluenesulphonate) or triflate (trifluoromethanesulphonate) and R is as defined for formula (I), with a corresponding compound of the general formula (III) where Y is chlorine, bromine or iodine and R′ is as defined for formula (I), wherein the reaction is carried out in the presence of a) stoichiometric amounts of elemental magnesium, based on the compound of the general formula (II), and b) amounts of an iron or cobalt compound from 0.01 to 50 mole percent of, based on the compound of the general formula (II), and, c) in the presence of a nitrogen-, oxygen- and/or phosphorus-containing additive in a catalytic or stoichiometric amount of from 0 to 200 mole percent, based on the compound of the general formula (II), and wherein the reaction is carried out as a one-pot process in which the organomagnesium compound (Grignard compound) formed in situ as intermediate is not isolated.