Patent ID: 7459171
Filing Date: 2008-12-02
Classification: A61K,A61P

Abstract:
1. A patch comprising: a non-occlusive backing liner and an inner liner, wherein the backing liner and the inner liner define a reservoir, wherein the non-occlusive backing liner exhibits a mean vapor transmission rate (MVTR) of more than 1000 g/m 2 day, the patch containing a formulation prepared by suspending or dispersing penetrants in a polar liquid in the form of fluid droplets surrounded by a membrane-like coating of one or several layers, said coating comprising at least two kinds or forms of amphiphilic substances with a tendency to aggregate, wherein said at least two substances differ by at least a factor of 10 in solubility in said polar liquid, wherein said penetrants are able to transport agents through the pores of an adaptable semi-permeable porous barrier or enable agent permeation through the pores of said barrier after penetrants have entered the pores, wherein the barrier is skin or mucosa of a mammalian body or cuticle of a plant, the pH of the formulation is between 3 and 10, and wherein the formulation is present in an amount corresponding to a desired dose per area.