Patent ID: 6747155
Filing Date: 2004-06-08
Classification: C07D

Abstract:
A process for the preparation of the magnesium salt of S-omeprazole trihydrate which comprises the following steps:(a) dissolving a magnesium source in water; (b) mixing a potassium salt of S-omeprazole with water; (c) adding the solution of the potassium salt of S-omeprazole of step (b) to the solution of step (a) to convert the potassium salt of S-omeprazole into the corresponding magnesium salt of S-omeprazole and precipitate the magnesium salt of S-omeprazole; (d) isolating the obtained magnesium salt of S-omeprazole; (e) treating the obtained magnesium salt of S-omeprazole with water; and (f) isolating and drying the obtained magnesium salt of S-omeprazole trihydrate.