Patent ID: 7745392
Filing Date: 2010-06-29
Classification: A61K,C07K

Abstract:
1. A compound having the formula: wherein C is selected from the group consisting of: wherein R is selected from the group consisting of hydrogen, optionally substituted C wherein Y is a group of the formula: wherein 2 to 6 Y groups are attached to C; wherein Z has the formula: wherein one Z is attached to C or is absent; wherein each L is separately selected to be a linker moiety comprising a molecular fragment having a molecular weight less than 1000; wherein each BB is separately selected to be a backbone moiety comprising an organic fragment having a molecular weight less than 5000; wherein each G is separately selected to be a guanidinium group covalently attached to BB and has the formula: or each G is separately selected from the group consisting of: each R wherein each T is a terminal group separately selected from the group consisting of hydrogen, an amine group, a carboxylic group, a N-terminal peptide or group that forms an N-terminal peptide bond with BB, a C-terminal peptide or group that forms a C-terminal peptide bond with BB, a reporting moiety, a targeting moiety, and a therapeutic moiety, or each T is separately absent; and wherein each n is separately selected to be an integer from 1 to 8.