Patent ID: 7780882
Filing Date: 2010-08-24
Classification: A61K,A61P,C12N

Abstract:
1. A method of preparing an antibody- or antibody fragment-targeted cationic immunoliposome complex comprising: a) preparing an antibody or antibody fragment; b) mixing said antibody or antibody fragment with a cationic liposome to form a cationic immunoliposome, wherein said antibody or antibody fragment is complexed with said cationic liposome, but is not chemically conjugated to said cationic liposome, and wherein said antibody or antibody fragment does not comprise a lipid tag; and c) mixing said cationic immunoliposome with a therapeutic or diagnostic agent to form said antibody- or antibody fragment-targeted cationic immunoliposome complex wherein said antibody- or antibody fragment-targeted cationic immunoliposome complex is about 50-400 nm in size.