Patent ID: 7332305
Filing Date: 2008-02-19
Classification: C12Q

Abstract:
1. An in vitro method for detecting a predisposition to a condition at least partially characterised by pathological or excessive formation of fibrotic tissue, the method comprising i) obtaining DNA comprising the Zf9 gene from a subject of interest, wherein said Zf9 gene comprises the sequence of SEQ ID NO:1 or the sequence of SEQ ID NO:2 and wherein nucleotide 43 of SEQ ID NO:1 and SEQ ID NO:2 is a polymorphic site, ii) amplifying a region of said Zf9 gene in said DNA comprising said polymorphic site, and iii) analyzing the amplification product resulting from step (ii) for the presence of guanosine at said polymorphic site, wherein the presence of guanosine at said polymorphic site indicates said subject is predisposed to said condition.