Patent ID: 6177445
Filing Date: 2001-01-23
Classification: A61P,C07D

Abstract:
A compound of Formula (I) ##STR14##whereinq and t are independently from 0 to 4; X.sup.1 and X.sup.2 are independently halogen; h.sup.a and h.sup.b are independently from 0 to 2;Z.sub.1 and Z.sub.2 are independently hydrogen, C.sub.1-6 alkyl C.sub.2-6 alkenyl or C.sub.2-6 alkynyl with the proviso that Z.sup.1 and Z.sup.2 are not both hydrogen;Y.sup.1, Y.sup.2, Y.sup.3 and Y.sup.4 are independently hydrogen, halogen or C.sub.1-3 alkoxy;m and p are independently 1 to 6;n and r are independently 0 to 4;with the proviso that if h.sup.a and h.sup.b are both 0, then r is 0 and n is 0 to 2;R.sup.1 to R.sup.14 are independently hydrogen, halogen, C.sub.1-3 alkoxy, or R.sup.2 and R.sup.3 together with the carbon atoms to which they are bonded, R.sup.5 and R.sup.6 together with the carbon atoms to which they are bonded, R.sup.9 and R.sup.10 together with the carbon atoms to which they are bonded, R.sup.12 and R.sup.13 together with the carbon atoms to which they are bonded, may independently form a methylenedioxy or ethylenedioxy moiety contained in a five or six-membered ring;W.sup.1 and W.sup.2 are carbon;the bond between the carbons attached to (CH.sub.2).sub.q and (CH.sub.2).sub.t may be a single or double bond: andA is a pharmaceutically acceptable anion.