Patent ID: 7799279
Filing Date: 2010-09-21
Classification: B01J,B01L,G01N,Y10S,Y10T

Abstract:
1. Apparatus for conducting an immunoassay or selective adsorption separation, the apparatus comprising: an assay unit having a passage formed in its center to form a packed bed; porous bed supports mounted in the assay unit at opposite ends of the packed bed; solid phase support beads located in the packed bed and having a reaction reagent mounted on their surface; an outlet from the assay unit having an outer diameter and located below the packed bed; two frusto-conical sealing surfaces on an upper surface of the assay unit above and opening into the packed bed; and a frusto-conical sample cup positioned between the two frusto-conical sealing surfaces, wherein the sample cup has a volume of from about 5 to about 100 μL; wherein the two frusto-conical sealing surfaces comprise an upper sealing surface dimensioned to form a fluid-tight, friction seal with a pipette holder, and a lower sealing surface abutting the packed bed and dimensioned to form a fluid-tight, friction seal with a device selected from the group consisting of straight wall tubing have an outer diameter of from about 0.75 to about 1 mm, hypodermic needles having a gauge of from about 19 to 21, and pipette tips having a volume of from about 10 μL to about 200 μl; and wherein the outer diameter of the outlet from the assay unit is dimensioned to form a fluid-tight, friction seal with the lower sealing surface when two assay units are nested together.