Patent ID: 7910741
Filing Date: 2011-03-22
Classification: A61P,C07D

Abstract:
1. A compound represented by formula (I): wherein R R (2) C2-10 alkenyl, (3) C2-10 alkynyl, (4) phenyl which may have C1-4 alkyl and/or a halogen atom(s), (5) C7-16 aralkyl which may have a substituent(s) of methyl, a halogen atom(s), hydroxy and/or methoxy, or (6) (C3-8 cycloalkyl)-(C1-4 alkyl)-which may have a substituent(s) of methyl, a halogen atom(s), hydroxy and/or methoxy; R (1) C1-6 alkyl which may have a substituent(s) selected from the group consisting of (a) hydroxy, (b) methoxy, (c) carboxy, (d) C3-8 cycloalkyl, (e) phenyl, and (f) oxo, (2) C3-8 cycloalkyl or phenyl, each of which may have a substituent(s) selected from the group consisting of C1-4 alkyl, hydroxy, cyano, oxo, carbamoyl, N-methylaminocarbonyl, carboxy, a halogen atom(s), methoxy, trifluoromethoxy, methylthio, methylsulfonyl, acetylamino, dimethylamino, acetyl, tetrazolyl, trifluoromethyl, and methylsulfonylamino, (3) C3-10 cycloalkenyl, or (4) thienyl, pyrazolyl, tetrahydropyranyl, isoxazolyl, isothiazolyl, thiadiazolyl, piperidinyl, pyridyl, pyrimidinyl, pyridazinyl, quinolyl, indolyl, benzothiazolyl, benzoisothiazolyl, benzotriazolyl, dioxaindanyl or benzodioxanyl, each of which may have a substituent(s) of C1-4 alkyl, hydroxy, oxo, a halogen atom(s), azide and/or trifluoromethyl; and R