Patent ID: 6717020
Filing Date: 2004-04-06
Classification: C07C

Abstract:
A method for producing a p-hydroxyphenylalkanol of formula (I): wherein R1 and R2 independently representa hydrogen atom, an C1-8 alkyl group, an C1-8 alkoxy group, a C5-8 cycloalkyl group, an C6-12 alkylcycloalkyl group, an C7-12 aralkyl group which may be substituted with an C1-8 alkyl group, a phenyl group which may be substituted with a C1-8 alkyl group, a phenoxy group which may be substituted with a C1-8 alkyl group, R3, R4, R5, R6 and R7 independently represent a hydrogen atom or an C1-8 alkyl group, and n denotes an integer from 0 to 7, which method comprises reacting a phenol compound of formula (II): wherein R1 and R2 respectively represent the same as defined above, with an unsaturated alcohol of formula (III):â€ƒR3R4C&boxH;C(R5)â€”C(R6)(R7)â€”(CH2)nâ€”OHâ€ƒâ€ƒ(III)wherein R3, R4, R5, R6, R7 and n respectively represent the same as defined above, in the presence of(A) at least one compound selected from the group consisting of an alkali metal, an alkali metal compound, an alkaline earth metal and an alkaline earth metal compound, and (B) at least one compound selected from the group consisting of a transition metal and a transition metal compound.