Patent ID: 6495515
Filing Date: 2002-12-17
Classification: A61K,C07K,C12N

Abstract:
A method of inhibiting inflammation mediated by infiltrating macrophages comprising administering to a subject having said inflammation, a therapeutically effective amount of a polypeptidehaving a molecular weight of approximately 30-40 kDa; having at least 50% amino acid sequence homology with the amino acid sequence as set forth in SEQ ID No. 4; and having the biological function of myxoma T7 interferon-&ggr; receptor; and binding to a polypeptide selected from the group consisting of CTAP-III, gro/MGSA, ENA-78, MCP-I, interleukin-8, RANTES, MIP-1&agr;, and MIP-1&bgr;.