Patent ID: 7635694
Filing Date: 2009-12-22
Classification: A61K,C07D,C07K

Abstract:
1. A compound, or enantiomer, stereoisomer, rotamer, tautomer, diastereomer and racemate of said compound, or a pharmaceutically acceptable salt, solvate or ester of said compound, said compound having the general structure shown in Formula I: wherein: R A and M are connected to each other such that the moiety: shown above in Formula I forms either a three, four, six, seven or eight-membered cycloalkyl; E is C(H) or C(R); L is C(H), C(R), CH R, R′, R Y is selected from the following moieties: wherein Y X is selected from O, NR G is NH or O; and R wherein each of said alkyl, aryl, heteroaryl, cycloalkyl or heterocyclyl can be unsubstituted or optionally independently substituted with one or more moieties selected from the group consisting of: hydroxy, alkoxy, aryloxy, thio, alkylthio, arylthio, amino, amido, alkylamino, arylamino, alkylsulfonyl, arylsulfonyl, sulfonamido, alkyl, aryl, heteroaryl, alkylsulfonamido, arylsulfonamido, keto, carboxy, carbalkoxy, carboxamido, alkoxycarbonylamino, alkoxycarbonyloxy, alkylureido, arylureido, halo, cyano, and nitro.