Patent ID: 8039460
Filing Date: 2011-10-18
Classification: A61P,C07D

Abstract:
1. A compound of Formula I: wherein: Z is selected from: A is C(R B is (C(R D is independently selected from N and C(R R R R azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, or morpholinyl, which is ring is unsubstituted or substituted with 1-5 substituents each independently selected from R R W is O, NR X is C or S; Y is O, (R R J is a bond, C(R V is selected from a bond, C(R G-L is selected from: N, N—C(R Q is independently selected from: T is independently selected from: R R p is selected from an integer in the range of 0 to 2 times q plus 1, for a substituent with q carbons; m is 0, 1 or 2; n is 1; s is 1, 2 or3; and pharmaceutically acceptable salts and individual diastereomers thereof.