Patent ID: 6184381
Filing Date: 2001-02-06
Classification: B01J,C07B,C07C

Abstract:
A method for producing optically active compounds, comprising subjecting a compound represented by the following formula (I); ##STR74##(wherein Ra and Rb independently represent a linear or cyclic hydrocarbon group or heterocyclic group, which may or may not have a substituent; W, represents oxygen atom, N--H, N--Rc, N--OH or N--O--Rd; and Rc and Rd independently represent a linear or cyclic hydrocarbon group or heterocyclic group, which may or may not have a substituent),to transfer-type asymmetric reduction in the presence of a transition metal complex and an optically active nitrogen-containing compound or a transition metal complex with an optically active nitrogen-containing compound as an asymmetric ligand, along with a hydrogen-donating organic or inorganic compound, to produce an optically active compound represented by the following formula (II); ##STR75##(wherein Ra and Rb independently represent the same as those described above; W.sub.2 represents OH, NH.sub.2, NH--Rc, NH--OH or NH--O--Rd; and Rc and Rd independently represent the same as those described above).