Patent ID: 8962657
Filing Date: 2015-02-24
Classification: A61K,A61P,C07C,C07D,Y02A

Abstract:
1. A compound of Formula I: wherein: R A is CH; R R R or R each R or two adjacent R R R provided that when R or a pharmaceutically acceptable salt, enantiomer, or diastereoisomer thereof; provided that the compound of Formula I is not: 5-(tert-butyl)-3′,4′-dichloro-3-(pyrrolidin-1-ylmethyl)-[1,1′-biphenyl]-2-ol; 5-((3r,5r,7r)-adamantan-1-yl)-4′-chloro-3-((dimethylamino)methyl)-[1,1′-biphenyl]-2-ol; 5-(tert-butyl)-4′-(dimethylamino)-3-((dimethylamino)methyl)-[1,1′-biphenyl]-2-ol; 5-(tert-butyl)-3-((tert-butylamino)methyl)-4′-chloro-[1,1′-biphenyl]-2-ol; 3,3′,5,5′-tetrakis((diethylamino)methyl)-[1,1′-biphenyl]-2,2′-diol; 4,4′″-dichloro-5′,5″-bis(pyrrolidin-1-ylmethyl)-[1,1′:3′,1″:3″,1″-quaterphenyl]-4″,6′-diol; 3,3′,5,5′-tetrakis(morpholinomethyl)-[1,1′-biphenyl]-2,2′-diol; 3,3′-bis((diethylamino)methyl)-5,5′-dimethoxy-[1,1′-biphenyl]-2,2′-diol; or 3-((diethylamino)methyl)-5,5′-dimethoxy-[1,1′-biphenyl]-2,2′-diol; or a pharmaceutically acceptable salt, enantiomer, or diastereoisomer thereof.