Patent ID: 6403561
Filing Date: 2002-06-11
Classification: A61K,A61P,C07D,C07K,C12Q,G01N

Abstract:
A compound selected from the group consisting of a compound of the formula wherein R1 is hydrogen or alkyl of 1 to 4 carbon atoms, R2 is hydrogen or alkyl of 1 to 2 carbon atoms with at least one of R1 and R2 being hydrogen, n is 0 or 1, m is 0 or 1 with n being different from m, R and Râ€² are individually hydrogen or alkyl of 1 to 2 carbon atoms, R3 is selected from the group consisting of R6 is selected from the group consisting of hydrogen, â€”F, â€”OCH3 and benzyloxyl, R8, R9 and R10 are individually selected from the group consisting of hydrogen, halogen, alkoxy of 1 to 4 carbon atoms, benzyloxy, â€”OH and alkyl of 1 to 4 carbon atoms, m and n indicating the bond orientation with respect to â€”(CH2)nâ€” or to N if n is 0 and to (â€”CRRâ€²)m or to â€”CHR4â€” if m is 0, R4 is R5 is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms, â€”(CH2)3â€”SCH3, benzyl, cyclohexylmethyl, â€”(CH2)3â€”OH â€ƒand or a salt thereof, or a hydrate thereof.