Patent ID: 6143728
Filing Date: 2000-11-07
Classification: A61K,A61P,Y02A,Y10S

Abstract:
A method of treating a disorder or disease characterized by T cell activation, comprising administering a compound having the formula: ##STR3## wherein: X.sub.2 =GhyCH--, GhyCCH.sub.3 -- or H--; X.sub.1, X'.sub.1 and X'.sub.2, independently=GhyCH-- or GhyCCH.sub.3 --; Z=--NH(CO)NH--, --(C.sub.6 H.sub.4)--, --(C.sub.5 NH.sub.3)-- or --A--(CH.sub.2).sub.n --A--, n=2-10, which is unsubstituted, mono- or di-C-methyl substituted, or a mono- or di-unsaturated derivative thereof; and A=independently --NH(CO)--, --(CO)NH--, --NH(CO)NH--, --NH-- or --O-- and salts thereof, with the proviso that the disorder or disease characterized by T cell activation excludes multiple sclerosis and arthritis.