Patent ID: 8318659
Filing Date: 2012-11-27
Classification: A61K,A61Q,C07K

Abstract:
1. A peptide-based organic sunscreen having the general structure (SBP m ) n —(OSCA) y , wherein a) SBP is a skin-binding peptide comprising between about 7 to about 50 amino acids and further comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10,11, 12, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, and 33; b) OSCA is an organic sunscreen agent; c) m ranges from 1 to about 100; d) n ranges from 1 to about 100; and e) y ranges from 1 to about 100, wherein the organic sunscreen agent is selected from the group consisting of of: para-aminobenzoic acid, ethyl para-aminobenzoate, amyl para-aminobenzoate, octyl para-aminobenzoate, ethylhexyl dimethyl para-aminobenzoate, ethylene glycol salicylate, phenyl salicylate, octyl salicylate, benzyl salicylate, butylphenyl salicylate, homomenthyl salicylate, triethanolamine salicylate, benzyl cinnamate, 2-ethoxyethyl para-methoxycinnamate, ethylhexyl methoxycinnamate, glyceryl mono(2-ethylhexanoate) dipara-methoxycinnamate, isopropyl para-methoxycinnamate, urocanic acid, ethyl urocanate, hydroxymethoxybenzophenone, dihydroxymethoxybenzophenone, sodium dihydroxymethoxybenzophenonedisulfonate, dihydroxybenzophenone, tetrahydroxybenzophenone, 4-tert-butyl-4′-methoxydibenzoylmethane, 2,4,6-trianilino-p-(carbo-2′-ethylhexyl-1′-oxy)-1,3,5-triazine, octocrylene, menthyl anthranilate, 2-(2-hydroxy-5-methylphenyl)benzotriazole, avobenzone, cinnamic acid, and organic polymers that scatter ultraviolet radiation.