Patent ID: 9156915
Filing Date: 2015-10-13
Classification: A61K,C07K,G01N

Abstract:
1. An anti-GCC antibody molecule comprising one or more light chain variable region and/or heavy chain variable regions selected from the group consisting of: a) MS7 heavy chain variable region Amino Acid Sequence SEQ ID NO:1; and/or MS7 light chain variable region Amino Acid Sequence SEQ ID NO:2; and b) MS20 heavy chain variable region Amino Acid Sequence SEQ ID NO:3; and/or MS20 light chain variable region Amino Acid Sequence SEQ ID NO:4; wherein the anti-GCC antibody molecule is i) an antibody that binds to human guanylyl cyclase C that is selected from the group consisting of: a monoclonal antibody and a chimeric antibody; or ii) an antigen-binding fragment of an antibody that binds to human guanylyl cyclase C that is selected from the group consisting of: a Fab fragment, Fab′ fragment, F(ab′)