Patent ID: 9198898
Filing Date: 2015-12-01
Classification: A61K,Y02A

Abstract:
1. A method of treating pruritus, said method comprising administering 3-[(3aR,4R,5S,7aS)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)-1,3,3a,4,5,6,7,7a-octahydroisoindol-2-yl]cyclopent-2-en-1-one (serlopitant) or a pharmaceutically acceptable salt, solvate or polymorph thereof to a patient in need of such treatment according to a schedule, said schedule comprising: a) first administering at least one loading dose; and b) second administering at least one therapeutically effective maintenance dose.