Patent ID: 8067584
Filing Date: 2011-11-29
Classification: A61P,C07D

Abstract:
1. A compound of formula (I): wherein M M one of R v is 0; R one of R and the other of R Z is —O—; R R R R R wherein: R R R R wherein: R R R p is 1; q is 0; r is 3; m is 0; n is 1; z is 0-3; R each R or a pharmaceutically acceptable salt or an in vivo hydrolysable ester thereof, wherein the hydrolysable ester is selected from the group consisting of: α-acyloxyalkyl ethers selected from acetoxymethoxy and 2,2-dimethylpropionyloxy-methoxy; and in vivo hydrolysable ester forming groups for hydroxy selected from alkanoyl, benzoyl, phenylacetyl, alkoxycarbonyl, dialkylcarbamoyl, N-(dialkylaminoethyl)-N-alkylcarbamoyl, dialkylaminoacetyl, and carboxyacetyl.