Patent ID: 7645572
Filing Date: 2010-01-12
Classification: C12Q

Abstract:
1. A method for determining an increased risk of restenosis after coronary angioplasty in a human male subject, said method comprising: (i) obtaining a biological sample from said human male subject, said biological sample comprising nucleic acids from said human male subject; (ii) detecting in said nucleic acids: a C at position 3932 of SEQ ID NO: 1 in at least one allele of the apolipoprotein E gene; an A at position 197 of SEQ ID NO: 3 in at least one allele of the tumor necrosis factor-α gene; and a T at position 831 of SEQ ID NO: 4 in both alleles of the G-protein β3 subunit gene; and (iii) correlating a C at position 3932 of SEQ ID NO: 1 in at least one allele of the apolipoprotein E gene, an A at position 197 of SEQ ID NO: 3 in at least one allele of the tumor necrosis factor-α gene, and a T at position 831 of SEQ ID NO: 4 in both alleles of the G-protein β3 subunit gene in said nucleic acids with an increased risk of restenosis after coronary angioplasty in said human male subject.