Patent ID: 7115640
Filing Date: 2006-10-03
Classification: A61P,C07D

Abstract:
1. A pharmaceutical composition, comprising: (a) a compound of formulae I: or a pharmaceutically acceptable derivative thereof, wherein: A, D, E and G are selected from (i) or (ii) as follows: (i) A and G are each independently selected from hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted cycloalkylalkyl, substituted or unsubstituted heterocyclylalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted aralkyl, substituted or unsubstituted heteroaralkyl, substituted or unsubstituted heteroarylium, substituted or unsubstituted heteroaryliumalkyl, halo, pseudohalo, OR R R J is O, S or NR R R where the alkyl, alkenyl, alkynyl, cycloalkyl, heterocyclyl, cycloalkylalkyl, heterocyclylalkyl, aryl, heteroaryl, heteroarylium, aralkyl, heteroaralkyl and heteroaryliumalkyl moieties of A, D, E, G, R each Q each Q each Q R R R R (b) one or more of the following: an antihyperlipidemic agent, a plasma HDL-raising agent, an anti-hypercholesterolemic agent, a cholesterol biosynthesis inhibitor, an acyl-coenzyme A:cholesterol acytransferase (ACAT) inhibitor, probucol, raloxifene, nicotinic acid, niacinamide, a cholesterol absorption inhibitor, a bile acid sequestrant, a low density lipoprotein receptor inducer, clofibrate, fenofibrate, benzofibrate, cipofibrate, gemfibrizol, vitamin B