Patent ID: 7585646
Filing Date: 2009-09-08
Classification: A61K,C07K

Abstract:
1. An isolated polynucleotide, comprising a nucleic acid sequence that hybridizes under conditions at least as stringent as 4×SSC at 65 degrees C. followed by washes at 65 degrees C. in 1×SSC, or 4×SSC with 50% formamide at 42 degrees C. followed by washes at 65 degrees C. in 1×SSC, to a complement of the polynucleotide having the nucleotide sequence of SEQ ID NO:1, wherein said nucleic acid sequence encodes a polypeptide that induces phosphorylation of a Stat3 polypeptide; and wherein the polypeptide encoded by the nucleic acid sequence comprises at least one amino acid sequence selected from: amino acids 50-60 of SEQ ID NO:2, amino acids 63-81 of SEQ ID NO:2, and amino acids 168-177 of SEQ ID NO:2.