Patent ID: 9090685
Filing Date: 2015-07-28
Classification: A61K,A61P,C07K

Abstract:
1. An isolated nucleic acid encoding the heavy chain, the light chain, or both, of a specific binding member that binds to human TGFβ1, TGFβ2 and TGFβ3, said specific binding member comprising an antigen-binding portion of an antibody wherein the heavy chain of the antibody comprises an HCDR1 comprising the amino acid sequence of SEQ ID NO: 3, an HCDR2 comprising the amino acid sequence of SEQ ID NO: 4, and an HCDR3 comprising the amino acid sequence of SEQ ID NO: 5; and wherein the light chain of the antibody comprises an LCDR1 comprising the amino acid sequence of SEQ ID NO: 8, an LCDR2 comprising the amino acid sequence of SEQ ID NO: 9, and an LCDR3 comprising the amino acid sequence of SEQ ID NO: 10.