Patent ID: 8049893
Filing Date: 2011-11-01
Classification: G01N,G03H,G06K

Abstract:
1. A method of identifying analytes that react with probes on encoded particles, comprising: (a) providing a support substrate having a plurality of the particles randomly distributed on the support substrate, wherein the particles have elongated bodies with codes that extend along the corresponding bodies, wherein the codes identify probes that are attached to the corresponding bodies, and wherein at least some of the probes comprise fluorescent labels from reactions with the analytes; (b) detecting fluorescent signals that are emitted from the fluorescent labels, the fluorescent signals emitting from random spatial locations along the support substrate; (c) detecting the codes of the particles at the random spatial locations along the support substrate, wherein the particles are submerged within a solution on the support substrate, wherein the particles have a material with a refractive index and the solution has a refractive index, the material of the particles and the solution being substantially index-matched; and (d) analyzing the codes and the fluorescent signals to identify the analytes that react with the probes on the particles.