Patent ID: 7601363
Filing Date: 2009-10-13
Classification: A61K

Abstract:
1. A cured sustained-release formulation for implantation, which comprises one of particle combinations, which is selected from the group consisting of (a), (b) and (c), and a carrier comprising a hydrophobic polymer, wherein the particle combination is dispersed in the carrier: (a) a particle combination which comprises particles comprising an active ingredient, particles comprising a carbonate, and particles comprising a substance which reacts with the carbonate in an aqueous solution to generate carbon dioxide; (b) a particle combination which comprises particles comprising an active ingredient and a carbonate, and particles comprising a substance which reacts with the carbonate in an aqueous solution to generate carbon dioxide; and (c) a particle combination which comprises particles comprising a carbonate, and particles comprising an active ingredient and a substance which reacts with the carbonate in an aqueous solution to generate carbon dioxide; and wherein