Patent ID: 8871883
Filing Date: 2014-10-28
Classification: A61L

Abstract:
1. An implantable medical device comprising a coating, the coating including a copolymer, the copolymer comprising at least one structural block comprising at least one biologically compatible structural moiety included in its backbone and at least one biologically active block comprising at least one biologically active moiety attached in its backbone, wherein the structural moiety comprises units derived from CH wherein the biologically active block comprises units derived from a monomer selected from: 2-acrylamido-2-methyl-1-propanesulfonic acid, poly(ethylene glycol) methacrylate, 3-sulfopropyl acrylate, 3-sulfopropyl methacrylate, N-vinylpyrrolidone, and acryloyl-, methacryloyl-, or 3-allyloxy-2-hydroxypropanesulfonic acid; wherein the copolymer has a formula wherein m1, n1 , p1, r1, m2, n2, p2, and r2 is each, independently, an integer and m1≧0, n1>0, p1≧0, r1>0, m2≧0, n2>0, p2≧0, r2 >0; with the provision that if m1=0, then p1>0; or if p1=0, then m1>0; or if m2=0, then p2 >0; or if p2 =0, then m2 >0; wherein each X, Y, and Z is, independently, hydrogen or an alkyl group; wherein each M and T is, independently, an ester group —C(O)—OR, or a substituted or unsubstituted aryl group; wherein R in the ester group is a straight-chained or branched substituted or unsubstituted alkyl group, or substituted or unsubstituted aryl group; and wherein Q is a biologically active moiety.