Patent ID: 7807624
Filing Date: 2010-10-05
Classification: A61K,A61L,C07K

Abstract:
1. A method for coating a medical device, the method comprising contacting the medical device with a biofunctional coating composition to form a medical device having at least one coated surface; wherein the biofunctional coating composition comprises a surface-binding domain and an endothelial-cell binding domain; wherein the surface-binding domain comprises a peptide which binds to a material of which the medical device is comprised; wherein the endothelial-cell binding domain comprises a peptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 95, SEQ ID NO: 96, SEQ ID NO: 97, SEQ ID NO: 98, and a combination thereof that binds to cells of endothelial cell lineage; and wherein the surface-binding domain and the endothelial-cell binding domain are coupled together.