Patent ID: 7754726
Filing Date: 2010-07-13
Classification: A61K,A61P,C07C,C07D,Y02A

Abstract:
1. A compound having formula (I): or a pharmaceutically acceptable salt thereof, wherein X is R R n is 0 or 1; Y is -L-R R L is —C(═O)NH—, —NH(C═O)—; V is -M-R M is —C(═O)NR R R R t is selected from 0, 1, 2 and 3; e is selected from 0, 1, 2 and 3; D is selected from a bond, an optionally substituted heterocyclyl, an optionally substituted aryl, —O—, —S—, —(C═O)—, —NR R wherein optionally substituted heterocyclyl, optionally substituted heteroaryl ring and optionally substituted fused bicyclic ring are heterocyclyl, heteroaryl ring and fused bicyclic ring which are unsubstituted or substituted by substituent selected from the group consisting of alkyl , arylalkyl, halo, hydroxy, oxo, alkanoyl, aryloxy, alkanoyloxy, amino, alkylamino, arylamino, aralkylamino, disubstituted amines in which the two amino substituents are selected from alkyl, aryl or aralkyl; akanoylamino, aroylamino, aralkanoylamino, substituted alkanoylamino, substituted arylamino, substituted aralkanoylamino, thiol, alkylthio, aralkylthio, alkylthiono, arylthiono, aralkylthiono, alkylsulfonyl, arylsulfonyl, aralkylsulfonyl, sulfonamido, substituted sulfonamido, nitro, cyano, carboxy, carbamyl, substituted carbamyl, alkoxybarbonyl, aryl, substituted aryl, guanidino, heterocyclyl, in which wherein the said substituent is further substituted, the further substituent is selected from alkyl, alkoxy, aryl and aralkyl; and wherein optionally substituted aryl is an aryl which is unsubstituted or substituted by one to four substituents selected from the group consisting of alkyl, halo, thrifluoromethoxy, trufluoromethyl, hydroxy, alkoxy, alkanoyl, alkanoyloxy, amino, arylamino, aralkylamino, dialkylamino, alkanocylamino, thiol, alkylthio, ureido, nitro, cyano, carboxy, carboxyalkyl, carbamyl, alkoxycarbonyl, alkylthiono, arylthiono, arylsulfonylamino, sulfonic acid, alkylsulfonyl, sulfonamido, and aryloxy; each of which may be further substituted with hydroxy, alkyl, alkoxy, aryl, or arylalkyl.