Patent ID: 6277860
Filing Date: 2001-08-21
Classification: A61P,C07D

Abstract:
A compound having the structure: ##STR13##whereinX.sup.1 is C, X.sup.2 is N, R.sup.1 is phenyl, R.sup.2 is absent, R.sup.3 is methyl, R.sup.4 and R.sup.5 together form the following: ##STR14##X.sup.1 is C, X.sup.2 is N, R.sup.1 is phenyl, R.sup.2 is absent, R.sup.3 and R.sup.4 are hydroxymethyl, and R.sup.5 is 2-buten-2-yl;X.sup.1 is C, X.sup.2 is N, R.sup.1 is phenyl, R.sup.2 is absent, R.sup.3 is methyl, R.sup.4 is formyl, and R.sup.5 is 4-hydroxy-2-buten-2-yl;X.sup.1, is C, X.sup.2 is N, R.sup.1 is phenyl, R.sup.2 is absent, R.sup.3 is methyl, R.sup.4 is hydroxymethyl, and R.sup.5 is 4-hydroxy-2-buten-2-yl;X.sup.1 is N; X.sup.2 is C; R.sup.1 is absent; R.sup.2 is phenyl; R.sup.3 is methyl; R.sup.4 is hydroxymethyl; and R.sup.5 is 2-buten-2-yl;X.sup.1 is N; X.sup.2 is C; R.sup.1 is absent; R.sup.2 is phenyl; R.sup.3 is methyl; R.sup.4 and R.sup.5, together with the carbon atoms to which they are attached, form the following ring: ##STR15##orX.sup.1 is N; X.sup.2 is C; R.sup.1 is absent; R.sup.2 is phenyl; R.sup.3 is methyl; R.sup.4 is 3-hydroxy-2-methyl-1-buten-1-yl; and R.sup.5 is OH; or a pharmaceutically acceptable salt thereof.