Patent ID: 7326726
Filing Date: 2008-02-05
Classification: A61P,C07D

Abstract:
1. A compound represented by Formula (I): or a pharmaceutically acceptable salt thereof, wherein R (a) H; (b) —C (c) —C (d) NO (e) NR (f) —CH(OR (g) —CONR (h) tetrazolyl, tetrazolinonyl, triazolyl, triazolinonyl, imidazolyl, imidozolonyl, oxazolyl, oxadiazolyl, isooxazolyl, thiazolyl, furyl, thienyl, pyrazolyl, pyrazolonyl, pyrrolyl, pyridyl, pyrimidinyl, pyrazinyl, or phenyl, any of which is optionally substituted with 1-3 independent substituents selected from i) F, Cl, Br, I, ii) —CN, iii) —NO (i) —C(R (k) piperidin-1-yl, morpholin-4-yl, pyrrolidin-1-yl, piperazin-1-yl or 4-susbstituted piperazin-1-yl, any of which is optionally substituted with 1-3 substituents selected from i) —CN, ii) —C(═O)(R R (a) H; (b) C (c) C (d) —C R (a) H; or (b) C R (a) H; (b) —C (c) —C (d) aryl or —(C (e) —C(═O)(R R (a) H; (b) —C (c) —O—C (d) —C (e) CN, NH R (a) C (b) —O—C (c) —C (d) —O-aryl, or —O—C (e) CN, N(R R (a) H; (b) C (c) —O—C (d) —C (e) —O-aryl, or —O—C (f) CN, N(R with the proviso that when R