Patent ID: 8168423
Filing Date: 2012-05-01
Classification: A61K,A61L,A61M,B01J,C12N,C12Q,G01N

Abstract:
1. A device for detecting nitrosothiol content in a solution, the device comprising: at least two electrodes disposed in a housing having opposed ends, wherein one of the at least two electrodes is a working electrode having a platinized tip and wherein the other of the at least two electrodes is a counter electrode; a glass capillary supported within the housing and protruding beyond one of the opposed ends of the housing, wherein the working electrode is substantially surrounded by the glass capillary, and the counter electrode is connected to the glass capillary within the housing; and a filter membrane disposed at an other of the opposed ends of the housing and configured to come in contact with the solution, the filter membrane and at least a portion of the working electrode having a material coated thereon, wherein the material comprises: wherein the material and the platinized tip are configured to come into contact with the solution containing nitrosothiols to convert the nitrosothiols to nitric oxide in order to detect the nitrosothiol content.