Patent ID: 6756395
Filing Date: 2004-06-29
Classification: A61P,C07D

Abstract:
A compound of the formula: a pharmaceutically acceptable salt or a prodrug thereof,wherein R1 is alkyl or â€”NR7R8, where each of R7 and R8 is independently hydrogen or alkyl; R2 is hydrogen or alkyl; each of R3, R4, R5; and R6 is independently hydrogen, halide, alkyl, â€”OR9 (where R9 is hydrogen, alkyl, a hydroxy protecting group, or cycloalkylalkyl), â€”SR10 (where R10 is hydrogen or alkyl), or â€”NR11R12 (where each of R11 and R12 is independently hydrogen, alkyl, or a nitrogen protecting group), provided R3, R4, R5, and R6 are not all simultaneously alkyl); or R3 and R4 together with atoms to which they are attached to form heterocyclyl, heteroaryl, or cycloalkyl; and R14 is hydrogen, lower alkyl or â€”OR15, where R15 is hydrogen, lower alkyl, or a hydroxy protecting group.