Patent ID: 9074182
Filing Date: 2015-07-07
Classification: C12N

Abstract:
1. A method of reducing the number of cells co-expressing TRA-1-60 and EpCAM in a mixed population of cells comprising: a) providing a mixed population of cells comprising the in vitro progeny of pPS cells, wherein the mixed population of cells comprises i) cells co-expressing TRA-1-60 and EpCAM, and ii) oligodendrocytes differentiated from the pPS cells; b) contacting the mixed population of cells with one or more ligands that specifically bind to EpCAM expressed on cells of the mixed population of cells; and c) separating the ligand bound EpCAM expressing cells from the rest of the mixed population of cells to thereby reduce the number of cells expressing TRA-1-60 in the mixed population of cells.