Patent ID: 8455668
Filing Date: 2013-06-04
Classification: C07D

Abstract:
1. A method for preparing hydroxymethylfurfural comprising the steps of: a. dissolving a triose in Solvent 1 to obtain a first reaction mixture, wherein the triose used in said method refers to a single compound having structural feature (III) or (IV), or a mixture thereof: wherein, in the above formulae (III) and (IV), R wherein in the above formula (V), R wherein Solvent 1 is any one or any combination of water, dimethyl sulfoxide, dimethyl formamide, dimethyl acetylamide, methylene dichloride, tetrahydrofuran, 1,4-dioxane, N-methyl pyrrolidinone, acetonitrile, cyclobutyl sulfone, trimethyl phosphate, and ethyl acetate; b. adding Alkaline Catalyst 1 into the first reaction mixture to make a reaction occur under agitation at a temperature of −40˜100° C. to obtain a hexose by condensation, wherein Alkaline Catalyst 1 is any one of Bronsted bases, Lewis bases, metal complexes, amino acids, and ion exchange resins; c. dissolving the condensation product hexose in Solvent 2 to obtain a second reaction mixture, wherein Solvent 2 is any one or an combination of dimethyl sulfoxide, dimethyl formamide, dimethyl acetylamide, N-methyl pyrrolidinone, tetramethylurea, cyclobutyl sulfone, trimethyl phosphate, and methyl propyl ketone; d. adding Acidic Catalyst 2 into the second reaction mixture, and heating the second reaction mixture with Acidic Catalyst 2 therein at a temperature of 80˜280° C. which is sufficient to form hydroxymethylfurfural, to obtain a third mixture containing said hydroxymethylfurfural, wherein Acidic Catalyst 2 is any one of Bronsted acids, Lewis acids, metal complexes, solid acids, heteropoly acids and ion exchange resins; wherein said hydroxymethylfurfural is a single compound having structural feature (I) or (II), or a mixture thereof