Patent ID: 6716590
Filing Date: 2004-04-06
Classification: A61K,G01N,Y02A

Abstract:
A process for making a composition comprising recovered parasite antigenic factor(s), said process comprising:a) forming a suspension in an aqueous medium of at least one of the following: (i) intact plasmodial parasite released from a quantity of red blood cells, (ii) intact red blood cells containing the blood stage of the plasmodial parasite, (iii) merozoites which released themselves from red blood cells, (iv) tissues having blood infected with said plasmodial parasite, and (v) tissues having plasmodial parasite infected blood, said suspension having said antigenic factor(s) said antigenic factors being insoluble in the aqueous medium; b) adding a non-ionic detergent to the suspension to disperse the antigenic insoluble factor(s); c) separating the dispersed antigenic, insoluble factors from the non-ionic detergent; and d) recovering said dispersed antigenic insoluble factor(s).