Patent ID: 9108937
Filing Date: 2015-08-18
Classification: A61P,C07D

Abstract:
1. A compound according to Formula I wherein: X is selected from the group consisting of C and N; Y is C R wherein groups (1) to (5) above are optionally substituted with 1 to 3 R each R ring A is selected from the group consisting of phenyl and pyridyl, wherein said phenyl and pyridyl are optionally substituted with one or more R each R wherein groups (2) to (7), (10), (11), (14) to (24), (27) and (30) to (36) above are optionally substituted from one up to the maximum number of substitutable positions with one or more substituents independently selected from the group consisting of: OH, CN, halo, —N(R) aryl at each occurrence is independently selected from the group consisting of: phenyl, naphthyl, anthryl and phenanthryl; heteroaryl at each occurrence independently means a 5- or 6-membered monocyclic aromatic or 9- or 10-membered bicyclic aromatic, wherein at least one atom in the aromatic is selected from the group consisting of N(R), O and S, the sulfur optionally oxidized to sulfone or sulfoxide, and the remaining atoms are selected from the group consisting of C, N(R), O and S, the sulfur optionally oxidized to sulfone or sulfoxide; heterocycle at each occurrence independently means a 5- or 6-membered monocyclic non-aromatic ring or 9- or 10-membered bi- or spiro-cyclic fully or partially unsaturated ring, wherein each said ring is optionally substituted with 1 to 2 oxo groups, wherein at least one atom of said 5- or 6-membered monocyclic non-aromatic ring or said 9- or 10-membered bi-or spiro-cyclic fully or partially unsaturated ring is selected from the group consisting of N(R), O and S, the sulfur optionally oxidized to sulfone or sulfoxide, and the remaining atoms are selected from the group consisting of C, N(R), O and S, the sulfur optionally oxidized to sulfone or sulfoxide; or a pharmaceutically acceptable salt thereof.