Patent ID: 6773717
Filing Date: 2004-08-10
Classification: A23K,C12P

Abstract:
A animal feed composition comprising chlortetracycline, wherein said animal feed composition is prepared by:(a) providing fast and second quantities of fermentation broth comprising chlortetracycline, said first and second quantities of fermentation broth produced by fermentation of an organism producing chlortetracycline, said first and second quantities of fermentation broth comprising fermentation solids and liquids; (b) adjusting the pH of the first quantity of fermentation broth to a value of about 7 or greater to produce fermentation broth containing chlortetracycline in the free base form; (c) lowering the pH of said second quantity of fermentation broth to a level sufficient to dissolve the chlortetracycline in said second quantity of fermentation broth; (d) removing solids from said pH-adjusted second quantity of fermentation broth and collecting liquid containing dissolved chlortetracycline; (e) adjusting the pH of said liquid containing dissolved chlortetracycline to a value of about 7 or greater to produce a suspension of chlortetracycline in the free base form; (f) mixing said fermentation broth containing chlortetracycline in the free base from step (b) and said suspension of chlortetracycline in the free base form from step (e); (g) removing liquids from the mixture of step (f) to produce a fermentation product having a low moisture content containing chlortetracycline in the free base form; and (h) sizing said low moisture content fermentation product to produce a particulate fermentation product containing chlortetracycline in the free base form having a predetermined particle size or range of particle sizes.