Patent ID: 6458371
Filing Date: 2002-10-01
Classification: A61K,A61Q,Y10S

Abstract:
A composition comprising 0.1 to 30% by total mass of said composition of a hydroximic acid derivative of the formula whereinR1 is a hydrogen atom or a C1-5 alkyl group; R2 is a hydrogen atom or a C1-5 alkyl group, a C3-8 cycloalkyl group or a phenyl group, optionally substituted by a hydroxy group or a phenyl group; or R1 and R2 together with the nitrogen atom to which they are attached form a 5 to 8 membered saturated or unsaturated ring that optionally comprises one or more further nitrogen or oxygen atoms, wherein said ring can be optionally condensed with a benzene ring; R3 is a hydrogen atom, a phenyl group, a naphthyl group or a pyridyl group wherein said groups can optionally be substituted by one or more halo atoms or C1-4 alkoxy groups; A is a group of the formula whereinR4 is a hydrogen atom or a phenyl group; R5 is a hydrogen atom or a phenyl group; m has a value of 0, 1 or 2; and n has a value of 0, 1 or 2; or a physiologically acceptable acid addition salt thereof as the active ingredient and a carrier that is in the form of a cream, lotion, foam or spray.