Patent ID: 8981075
Filing Date: 2015-03-17
Classification: C12N,G01N

Abstract:
1. An aptamer comprising: a preceding region having a random polynucleotide sequence consisting of from 1 to 10 nucleotides; a first region, at a 3′ end of the preceding region, consisting of nnnnCT wherein each n is independently selected from A, T, G and C; a second region consisting of nnCTTT wherein each n is independently selected from A, T, G and C, and at least one part of the second region is complementary to the first region; and a third region positioned between the first region and the second region and consisting of a random polynucleotide sequence having from 3 to 30 nucleotides, wherein the aptamer is capable of binding to prostate-specific antigen (PSA).