Patent ID: 8324408
Filing Date: 2012-12-04
Classification: C07D

Abstract:
1. A method for the preparation of dronabinol (A) ((6aR-trans)-6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-Pentyl-6H-dibenzo[b,d]pyran-1-ol, Δ 9 -tetrahydrocannabinol (Δ 9 -THC)) from cannabidiol (CBD) (B) ((2-[1R-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzoldiol)) comprising the steps of: (a) providing cannabidiol (CBD)(B) in an organic solvent; and (b) cyclizing the CBD to Δ