Patent ID: 8748484
Filing Date: 2014-06-10
Classification: A61K,A61P,C07F

Abstract:
1. An anti-cancer ruthenium complex having formula 1: wherein: R R n independently represents 0 or 1; when n represents 1, X independently represents O, S, or NR when n represents 0, a single bond exists between the two carbon atoms adjacent to (X) R Y independently represents O or S Z independently represents O, S, or NR R L represents a carbonyl, Ph aryl is selected from the group consisting of phenyl or a 5 or 6 member heterocyclic aromatic ring comprising at least one ring heterocyclic atom or group selected from the group consisting of —O—, —S—, —NH—, or —NCH carbocycloalkyl groups are 5 or 6 member non-aromatic carbocyclic rings; aryl and carbocycloalkyl groups independently are unsubstituted, or are substituted at any position with one or more substituents; aryl substituents independently are R carbocycloalkyl substituents independently are C