Patent ID: 6156758
Filing Date: 2000-12-05
Classification: C07D

Abstract:
A compound of the formula (I) ##STR9## wherein X, Y and Z are independently CH or N;n is 0 or 1;R.sub.1 is selected from OH, alkoxy, aryloxy, aralkoxy and guanidinyl;R.sub.2 and R.sub.3 are independently selected from H, halogen, amino, hydroxyl, nitro, cyano and carboxyl;R.sub.4 is H, alkyl or acyl;R.sub.5 is selected from H, hydroxyl, halogen, nitro, alkyl, alkoxy, amino, cyclic amino, alkylamino, arylamino and aralkylamino wherein the alkyl, aryl and cyclic moieties are optionally substituted;R.sub.6 and R.sub.7 are independently selected from H, alkyl, alkoxy, halogen and amino; andR.sub.8 and R.sub.9 are independently selected from H, alkyl, alkoxy, acyl, acyloxy, alkoxycarbonyl, hydroxyl, halogen, amino and carboxyl;provided that when R.sub.2 and R.sub.5 are both NH.sub.2, R.sub.3 is Cl, R.sub.6 and R.sub.7 are both H and R.sub.8 and R.sub.9 are both OMe, Z is N and n is 0 then R.sub.1 is other than guanidinyl.