Patent ID: 8809364
Filing Date: 2014-08-19
Classification: A61K,A61P,C07D

Abstract:
1. A compound of formula (I): wherein: R one of R a) a bicyclic aryl of formula (II) or a bicyclic heteroaryl of formula (II): b) a polycyclic heteroaryl containing more than 14 ring atoms optionally substituted by one or more substituents selected from the group consisting of oxo, thioxo, cyano, nitro, halo, haloalkyl, alkyl, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, optionally substituted heterocyclyl, —R c) a bridged bicyclic aryl of formula (III) or a bridged bicyclic heteroaryl of formula (III): each R each R each R each R each R each R each R as an isolated stereoisomer or a mixture thereof, or as a pharmaceutically acceptable salt thereof.