Patent ID: 8492571
Filing Date: 2013-07-23
Classification: A61K,A61P,C07F

Abstract:
1. A process for preparing a mixture of sn-1-docosahexaenoyl/sn-2-hydroxyl molecular species of fish liver lysophosphatidylcholine, the process comprising: immediately freezing a fresh fish liver after withdrawing from a saltwater fish; fragmenting the frozen fish liver into small fragments; extracting crude lipids from the liver fragments by using organic solvents; isolating of the crude phospholipids from the extracted lipids by the precipitation of the crude phospholipids in acetone for about 12 to about 15 hours at about −20 C.°; and drying the precipitated phospholipids; further purifying the fish liver lysophosphatidylcholine to at least about 85% purity from the phospholipids by silica chromatography.