Patent ID: 6689365
Filing Date: 2004-02-10
Classification: A61P,C07K

Abstract:
A glycosylated or nonglycosylated protein having FSH activity and LH activity, of the formulaFSH&bgr;-(linker1)n1-LH&bgr;(1-X)-(linker2)n2-&agr;wherein FSH&bgr; is a vertebrate follicle stimulating hormone &bgr; subunit or a variant thereof; LH&bgr;(1-X) refers to a &bgr; subunit of a vertebrate luteinizing hormone containing positions 1-X where X is an integer of 114-121 or a variant thereof; each â€œlinkerâ€  is a hydrophilic, flexible amino acid sequence containing 1-100 amino acid residues; each n is a 0 or 1; and &agr; is the &agr; subunit of a vertebrate glycoprotein hormone or a variant thereof.