Patent ID: 6492527
Filing Date: 2002-12-10
Classification: C07C,C07D

Abstract:
A process for preparing a compound of formula I: comprised of carbonylating an amidrazone of formula (A) with a carbonylating agent, wherein formula (A) is: whereinX and Y are independently selected from hydrogen, halogen, nitro, and amino; Z is selected from hydrogen, halogen, alkyl, alkoxy, nitro, amino, or alkylsulfonylamino; W is â€”NHR where R is hydrogen, alkyl, or haloalkyl; and, R1 is hydrogen, alkyl, haloalkyl, alkoxy, acetyl, or aryl; and, said carbonylating agent is of the formula; wherein R2 and R3 are the same and are selected from the group consisting of dichloromethoxy, trichloromethoxy, imidazol-1-yl, 2-methylimidazol-1-yl, phenoxy or naphthoxy wherein phenoxy and naphthoxy are optionally substituted with halogen, alkoxy, or nitro; and, wherein said carbonylating is conducted i) in at least one organic solvent; ii) at a temperature in the range of 10Â° C. to 200Â° C.; iii) during a period of time of up to 20 hours.