Patent ID: 7083805
Filing Date: 2006-08-01
Classification: A61J,A61K,B30B,G03H

Abstract:
1. A method of producing a microrelief on an ingestible dosage form having a core which can contain a pharmaceutically active substance and a pharmaceutically acceptable carrier, comprising the steps of: a. coating said core with a layer of a thermo-formable material that can receive and retain a holographic diffraction pattern; b. providing a plate having a holographic diffraction pattern formed on at least a portion of a first surface thereof; c. transporting said coated cores to a position opposite said first surface; d. heating at least one of said plate and said coating during or prior to the time when they are in said opposed relationship; e. pressing said first surface into said coating to replicate said holographic diffraction pattern in said coating; f. cooling said coating thus replicated; and g. demolding said first plate surface from said coating wherein said heating raises the temperature of said diffraction pattern to a temperature in the range of 90–150° C., and wherein said pressing occurs for about 0.3 to 3.0 second.