Patent ID: 6586003
Filing Date: 2003-07-01
Classification: A61K,Y10S

Abstract:
A micellar formulation consisting essentially of lipid components, a nucleic acid and an aqueous carrier, wherein the lipid components comprise a cationic amphiphile component, and a nonionic surfactant component,wherein the nonionic surfactant component is a synthetic detergent selected from the group consisting of a sorbitan fatty acid ester, a sorbitan polyoxyethylene fatty acid ester, a Pluronic surfactant and an octoxynol surfactant, and wherein the cationic amphiphile component is present in an amount from about 30 to about 90 weight % of the total lipid components and the nonionic surfactant component is present in an amount from about 70 to about 10 weight % of the total lipid components, and wherein the micellar formulation is suitable for administration to a human.