Patent ID: 7108891
Filing Date: 2006-09-19
Classification: B01J,C40B

Abstract:
1. A method of making a microarray comprising the following steps in the order of: providing a support; coating on the support a receiving layer to receive microspheres, the receiving layer being capable of undergoing sol/gel transition by thermal gelation; coating on the receiving layer a dispersion of microspheres in a carrier fluid, wherein the carrier fluid contains at least one crosslinking agent; allowing the at least one crosslinking agent to migrate into the receiving layer; allowing the microspheres to partially submerge into the receiving layer; inducing sol/gel transition by thermal gelation of the receiving layer with the at least one crosslinking agent, thus immobilizing the microspheres; evaporating off the carrier fluid; and allowing crosslinking between the receiving layer and the crosslinker in the carrier fluid initiated by thermal gelation to go to completion.