Patent ID: 6121279
Filing Date: 2000-09-19
Classification: A61P,C07D

Abstract:
A compound of formula I ##STR9## in which R1 is hydroxyl, 1-4C-alkoxy, 3-7C-cycloalkoxy, 3-7C-cycloalkylmethoxy or completely or predominantly fluorine-substituted 1-4C-alkoxy,R2 is hydroxyl, 1-4C-alkoxy, 3-7C-cycloalkoxy, 3-7C-cycloalkylmethoxy or completely or predominantly fluorine-substituted 1-4C-alkoxy,or in whichR1 and R2 together are a 1-2C-alkylenedioxy group,R3 is hydrogen or 1-4C-alkyl,R31 is hydrogen or 1-4C-alkyl,or in whichR3 and R31 together are a 1-4C-alkylene group,R4 is hydrogen or 1-4C-alkyl,R5 is hydrogen,R51 is hydrogen,or in whichR5 and R51 together are an additional bond,R6 is SO.sub.2 --N(R7)R8 or CO--N(R9)R10, whereR7 and R8 independently of one another are hydrogen, 1-7C-alkyl, 3-7C-cycloalkyl, 3-7C-cycloalkylmethyl or an unsubstituted or R12- and/or R13-substituted phenyl radical, or where R7 and R8, together and including the nitrogen atom to which both are bonded, are a 1-pyrrolidinyl, 1-piperidyl, 1-hexahydroazepinyl or 4-morpholinyl radical,R9 is hydrogen or 1-4C-alkyl,R10 is an unsubstituted or R11-substituted pyridyl radical or an unsubstituted or R12- and/or R13-substituted phenyl radical, whereR11 is halogen, nitro, carboxyl, 1-4C-alkoxy, 1-4C-alkoxycarbonyl, 1-4C-alkyl, trifluoromethyl or completely or predominantly fluorine-substituted 1-4C-alkoxy,R12 is hydroxyl, halogen, 1-4C-alkyl or 1-4C-alkoxy,R13 is hydroxyl, halogen, nitro, cyano, carboxyl, 1-4C-alkyl, trifluoromethyl, 1-4C-alkoxy, 1-4C-alkoxycarbonyl, 1-4C-alkylcarbonyloxy, amino, mono- or di-1-4C-alkylamino, aminocarbonyl, mono- or di-1-4C-alkylaminocarbonyl or completely or predominantly fluorine-substituted 1-4C-alkoxy,or salt thereof.