Patent ID: 8080401
Filing Date: 2011-12-20
Classification: C11D,C12N

Abstract:
1. An isolated α-amylase variant having amylase activity and having at least one amino acid substitution with respect to a predetermined α-amylase starting molecule, wherein in said at least one amino acid substitution an asparagine (N) or a glutamine (Q) residue on the surface of said starting molecule is replaced with A, C, F, G, H, I, K, L, M, P, R, S, T, V, W or Y in the variant, and wherein the starting molecule is an α-amylase having at least 96% sequence identity to positions +1 to 484 of SEQ ID NO: 2 obtained from Bacillus sp. A 7-7 (DSM 12368), said α-amylase variant having improved stability at elevated temperatures or alkaline pH.