Patent ID: 8263806
Filing Date: 2012-09-11
Classification: C07C

Abstract:
1. A process for preparing a sulfonamide of formula I wherein: R R by reacting a m-nitrobenzoyl chloride of formula II wherein the variables R with an amino sulfone of formula III wherein the variables R under the influence of B equivalents of alkali metal or alkaline earth metal hydroxide as base, wherein, in a first step, the amino sulfone of formula III is reacted with B1 equivalents of alkali metal or alkaline earth metal hydroxide, and, in a second step, the reaction mixture resulting from the first step is reacted with m-nitrobenzoyl chloride of formula II and B2 equivalents of alkali metal or alkaline earth metal hydroxide; wherein B is 1.5-3 equivalents of alkali metal or alkaline earth metal hydroxide with respect to the amino sulfone of formula III;