Patent ID: 6303375
Filing Date: 2001-10-16
Classification: A61K,C12M,C12N

Abstract:
A matrix for supporting cells having an upstream surface, a downstream surface and thickness between them, said matrix having formed thereina plurality of cone shaped pores along the thickness of the matrix, wherein an average pore diameter of an opening of said cone shaped pores in the upstream surface ranges from 500 to 1500 .mu.m, said pore diameter decreases from the upstream surface to the downstream surface, and the average pore diameter of the cone shaped pores in the whole matrix ranges from 100 to 1000 .mu.m, anda plurality of communicating pores communicating with the cone shaped pores and with each other, having an average diameter ranging from 5 to 100 .mu.m and the diameter of the communicating pores decreases from a pore opening positioned near one surface of the matrix or near an interior surface of said cone shaped pores to a pore opening positioned remote from said surfaces.