Patent ID: 7736855
Filing Date: 2010-06-15
Classification: C12N,G01N

Abstract:
1. A process for separating hybridized microorganisms from non-hybridized microorganisms comprising the steps of: a. hybridizing a microorganism of a plurality of microorganisms with an enzyme-labeled probe that hybridizes to a nucleic acid of the microorganism, to produce hybridized microorganisms and non-hybridized microorganisms; b. exposing the hybridized microorganisms to an antigen that is activated by the enzyme to produce labeled microorganisms; c. exposing the labeled microorganisms to a substrate that is coated with an antibody specific to the antigen to produce a bound microorganism-substrate complex; and d. separating the bound microorganism-substrate complex from the non-hybridized microorganisms.