Patent ID: 8980857
Filing Date: 2015-03-17
Classification: A61K,A61P,C12N,C12Q,Y02A

Abstract:
1. A method of upregulating a function of and/or the expression of a PAR4 polynucleotide in a biological system comprising: contacting said system with at least one antisense oligonucleotide 12 to 26 nucleotides in length wherein said at least one oligonucleotide is specific for and specifically hybridizes to a natural antisense polynucleotide of the PAR4 gene and has at least 80% sequence identity to a reverse complement of a natural antisense of a PAR4 polynucleotide; thereby upregulating a function of and/or the expression of the PAR4 polynucleotide wherein said natural antisense polynucleotide consists essentially of SEQ ID NO: 2.