Patent ID: 7816368
Filing Date: 2010-10-19
Classification: A61P,C07D

Abstract:
1. A method for the treatment of a disease caused or exacerbated by the proliferation of tumour cells, which method comprises administering to a patient in need thereof an effective amount of a compound of formula (I): in which: R R R R or an acid addition salt thereof, where the disease is selected from breast cancer, lung cancer, cancer of the small intestine, cancer of the colon, cancer of the rectum, cancer of the respiratory tract, cancer of the oropharynx, cancer of the hypopharynx, cancer of the oesophagus, liver cancer, stomach cancer, cancer of the bile ducts, cancer of the gall bladder, cancer of the pancreas, cancer of the urinary tract, cancer of the female genital tract, choriocarcinoma cancer, trophoblastic cancer, cancer of the male genital tract, tumors of the germinal cells, cancers of the endocrine glands, skin cancers, tumors of the brain, tumors of the nerves, tumours of the eyes, tumours of the meninges, and solid tumours resulting from haematopoietic malignant tumours.