Patent ID: 9103817
Filing Date: 2015-08-11
Classification: G01N

Abstract:
1. A method of determining the clotting or gelling characteristics of coagulating blood, the method comprising: a) providing a sample of whole blood; b) carrying out the following steps using a rheometer: c) utilizing a relationship between dynamic rigidity G′, loss modulus G″, viscoelastic stress relaxation exponent α and angular frequency d) monitoring a change in G″/G′ with time to establish the time at which the blood first gels or clots wherein each frequency of the harmonically time-varying stress or harmonically time-varying strain that is applied to the blood is measured consecutively and each frequency is composed of more than one harmonic frequency formed by concatenation of two separate multiplexed waveforms each having identical frequency components but different amplitude so that dynamic properties of the blood is measured over time as the blood gels or clots.