Patent ID: 8614074
Filing Date: 2013-12-24
Classification: C11C

Abstract:
1. A process for the preparation of a composition comprising the cis9, trans11 and trans10, cis12 isomers of conjugated linoleic acid (CLA), which comprises: providing a mixture comprising the free acids of cis9, trans11 and trans10, cis12 isomers of conjugated linoleic acid (CLA) in which one of the cis9, trans11 and trans 10, cis12 isomers is present in a first weight ratio X of from 1.3:1 to 4:1 with respect to the other isomer; subjecting the mixture to a crystallization step to form a composition comprising the cis9, trans11 and trans10, cis12 isomers in which one of the cis9, trans11 and trans10, cis12 isomers is present at a second weight ratio Y with respect to the other isomer, wherein Y is greater than X, wherein the composition comprises at least 60% by weight of the cis9, trans11 isomer or the trans10, cis12 isomer, based on the total amount of C18:2 fatty acids in the composition, wherein the mixture is provided by at least partially esterifying a composition comprising CLA with an enzyme that is selective for the cis9, trans11 isomer compared to the trans10, cis12 isomer to form an ester fraction enriched in the cis9, trans11 isomer compared to the trans10, cis12 isomer and a free acid fraction enriched in the trans10, cis12 isomer compared to the cis9, trans11 isomer and separating the ester fraction and the free fatty acid fraction.