Patent ID: 8142994
Filing Date: 2012-03-27
Classification: C12Q,G16B

Abstract:
1. A method for determining the prognosis for an AML-affected subject, said method comprising the steps of: determining, in a sample obtained from the subject, a level of expression of each of at least MYH11, CLIPR-59, ST18, NRP1 and CLECSF13 from cluster #9, corresponding to the AML class of inv(16); establishing the similarity of expression levels between the at least MYH11, CLIPR-59, ST18, NRP1 and CLECSF13 in the AML-affected subject and the at least MYH11, CLIPR-59, ST18, NRP1 and CLECSF13 in subjects selected from the inv(16) class; and assigning to the AML-affected subject a prognosis based on the established similarity of expression levels between the at least MYH11, CLIPR-59, ST18, NRP1 and CLECSF13 in the AML-affected subject and the at least MYH11, CLIPR-59, ST18, NRP1 and CLECSF13 in subjects selected from the inv(16) class.