Patent ID: 6127350
Filing Date: 2000-10-03
Classification: A61K,A61P,C07F

Abstract:
A method of treating or preventing a neoplastic disease in a patient, wherein the neoplastic disease is chosen from cancers of the hemopoietic and immune system and cancers of the pancreas, colon, breast, thyroid, brain, lung, head and neck, said method comprising administering to a patient in need of such therapy, a therapeutically effective amount of a compound represented by formula I ##STR17## wherein: Z.sup.1, Z.sup.2, Z.sup.3 and Z.sup.4 are each --OR wherein R is independently chosen from --H and straight or branched alkyl comprising from 1 to 8 carbon atoms;X.sup.1 and X.sup.2 are independently straight or branched alkyl comprising from 1 to 8 carbon atoms;X.sup.3 is --H;A is --(CH.sub.2).sub.n --, wherein n is an integer from 1 to 7;B is chosen from --H and alkyl comprising from 1 to 4 carbon atoms; andt is 1;or a pharmaceutically acceptable salt thereof.