Patent ID: 6545013
Filing Date: 2003-04-08
Classification: A61P,C07D,Y10S

Abstract:
A compound of formula (1): wherein Ar1 is an optionally substituted 2,7-naphthridin-1-yl group; L2 is a covalent bond or a linker atom or group; Ar2 is an optionally substituted aromatic or heteroaromatic chain; Alk is a chain â€”CH2CH(R)â€”, â€”CH&boxH;C(R)â€”, â€ƒin which R is a carboxylic acid (â€”CO2H) or a derivative or biostere thereof; R1 is a hydrogen atom or a C1-6alkyl group; L1 is a covalent bond or a linker atom or group; Alk1 is an optionally substituted aliphatic chain; n is zero or the integer 1; R2 is a hydrogen atom or an optionally substituted heteroaliphatic, cycloaliphatic, heterocycloaliphatic, polycycloalphatic, heteropoly-cycloaliphatic, aromatic or heteroaromatic group; and the salts, solvates, hydrates and n-oxides thereof.