Patent ID: 6096771
Filing Date: 2000-08-01
Classification: A61P,C07D

Abstract:
A compound of formula (I) ##STR23## wherein: R.sup.1 represents a hydrogen atom; a halogen atom; an alkyl group having from 1 to 6 carbon atoms; an alkyl group having from 1 to 4 carbon atoms and substituted by a halogen atom or an alkoxy group having from 1 to 4 carbon atoms; an alkoxy group having from 1 to 6 carbon atoms; a halogeno alkoxy group having from 1 to 6 carbon atoms; a hydroxyl group; an alkylthio group having from 1 to 6 carbon atoms; an amino group; a monoalkylamino group in which said alkyl moiety has from 1 to 6 carbon atoms; a dialkylamino group in which each alkyl moiety independently has from 1 to 6 carbon atoms; an alkanoyl group having from 1 to 6 carbon atoms; an alkanoylamino group having from 1 to 6 carbon atoms; an alkanoyloxy group having from 1 to 6 carbon atoms; an alkoxycarbonyl group having from 1 to 6 carbon atoms; a carboxy group; an (alkylthio)thiocarbonyl group in which said alkylthio moiety has from 1 to 6 carbon atoms; a carbamoyl group; a monoalkylcarbamoyl group in which said alkyl moiety has from 1 to 6 carbon atoms; a dialkylcarbamoyl group in which each alkyl moiety independently has from 1 to 6 carbon atoms; a nitro group; or a cyano group;R.sup.2 represents an amino group;m represents an integer of from 2 or 3;n represents an integer of from 1 to 6;ring A represents a phenyl ring fused with the isoxazole ring, a naphthyl ring fused with the isoxazole ring, or an aromatic heterocycle with a 5- or 6-membered ring including one or two heteroatoms selected from the heteroatom group comprising oxygen atoms, nitrogen atoms and sulfur atoms, fused with the isoxazole ring; andX represents an oxygen atom or a sulfur atom;the substituents R.sup.1 are the same or different;or a pharmaceutically acceptable salt thereof.