Patent ID: 7060290
Filing Date: 2006-06-13
Classification: A61K,A61P,C07F

Abstract:
1. A compound having the general formula I: wherein the LINKER is one or more of the groups selected from the group consisting of (i) unsubstituted alkyl, (ii) substituted or unsubstituted alkenyl, (iii) unsubstituted alkanoyl, (iv) unsubstituted alkenoyl wherein the double bond is cis, and (v) (ortho or para) carbonyl-substituted aryl; and wherein the subtituent is each an independent group or linked together thereby forming a ring; and wherein X is an O or S atom and wherein the substituent is each an independent group or linked together thereby forming a ring; and wherein the therapeutic agent is selected from the group consisting of (i) testosterone, (ii) cardiotonic steroids selected from the group consisting of digitoxigenin, digoxigenin and ouabuquenin, (iii) dehydroepiandrosterone (DHEA), (iv) eticholanolone, (v) pregnenolone, (vi) estradiol, (vii) estrone, (viii) dexamethasone, (ix) hydrocortisone and (x) paclitaxel.