Patent ID: 6133278
Filing Date: 2000-10-17
Classification: A61K

Abstract:
A method for treating a cancer cachexia in mammals without treating the cancer which comprises administering to a mammal in need of treatment a pharmaceutically effective amount of a quinone derivative of the formula: ##STR31## wherein R.sup.1 and R.sup.2 independently represent a hydrogen atom, an alkyl group, an alkenyl group or an alkoxy group, or may bind together to form --CH.dbd.CH--CH.dbd.CH--; R.sup.3 represents a hydrogen atom, an alkyl group or an alkenyl group; R.sup.4 represents an optionally substituted nitrogen-containing heterocyclic group; R.sup.5 represents a hydrogen atom, an alkyl group, an optionally substituted hydroxy-alkyl group or an optionally esterified or amidated carboxyl group; Z represents a group represented by: ##STR32## R.sup.0 represents a hydrogen atom or an alkyl group; n represents an integer from 0 to 12; m represents an integer from 0 to 3; k represents an integer from 0 to 7; provided that when m is 2 or 3, each Z within the [ ] independently represents a group defined above for Z and each k within the [ ] independently represents an integer from 0 to 7, or a pharmaceutically acceptable salt thereof.