Patent ID: 8242175
Filing Date: 2012-08-14
Classification: A61P,C07D

Abstract:
1. A compound of formula (I) wherein: Q is a bond, CH X is CH or nitrogen; Y is a bond, CH Z is CH or nitrogen; R R R R R R R R R and the pharmaceutically acceptable salts thereof; with the proviso that when X is nitrogen, Y cannot be oxygen or NR and with the exclusion of the following compounds: (E)-N-Hydroxy-3-(4-{(E)-3-[4-(4-methyl-piperazin-1-yl)-phenyl]-3-oxo-propenyl}-phenyl)-acrylamide; (E)-N-Hydroxy-3-{4-[(E)-3-(4-morpholin-4-yl-phenyl)-3-oxo-propenyl]-phenyl}-acrylamide; (E)-3-{3-Fluoro-4-[(E)-3-(4-morpholin-4-yl-phenyl)-3-oxo-propenyl]-phenyl}-N-hydroxy-acrylamide.