Patent ID: 6989138
Filing Date: 2006-01-24
Classification: A61K

Abstract:
1. A composition comprising, (1) a radiopharmaceutical precursor comprising a target moiety selected from the group consisting of an antibody, a Fab antibody fragment, a F(ab)′ 2 antibody fragment, an epitope binding complementarity determining region derived from an antibody, a peptide, a growth factor, a receptor binding fragment of a growth factor, a hormone, a steroid, a receptor binding nucleic acid, a receptor binding monosaccharide, a receptor binding disaccharide, a receptor binding oligosaccharide, a receptor-binding lipid, a receptor binding benzodiazepine and a receptor binding antibiotic; and (2) a stabilizing amount of a mixture of a hydrophilic thioether of the formula: wherein: R is C R R wherein one of Y and Z is selected from the group consisting of O, S, C═O, and (CHR each R R R