Patent ID: 6638721
Filing Date: 2003-10-28
Classification: A61K,C07C,C12N

Abstract:
A method for identifying a compound which binds to a polypeptide, said method comprising contacting a polypeptide, or a cell expressing a polypeptide, with a test compound, and determining whether the polypeptide binds to the test compound; wherein said polypeptide is selected from the group consisting of:a) the polypeptide having the amino acid sequence set forth in SEQ ID NO:14, wherein said polypeptide has protein kinase activity; b) a polypeptide comprising a fragment of at least 15 contiguous amino acids of SEQ ID NO:14, wherein said polypeptide has protein kinase activity; c) a polypeptide encoded by a nucleic acid molecule which hybridizes to the complement of the sequence set forth in SEQ ID NO:13 or 15 under stringent conditions comprising hybridization in 6Ã— sodium chloride/sodium citrate at about 45Â° C., followed by one or more washes in 0.2Ã—SSC, 0.1% SDS at 50Â° C. to 65Â° C., wherein said polypeptide has protein kinase activity; and, d) a polypeptide having at least 75% sequence identity to the amino acid sequence of SEQ ID NO:14, wherein said polypeptide has protein kinase activity.