Patent ID: 6130237
Filing Date: 2000-10-10
Classification: C07D

Abstract:
A compound of the formula (I): ##STR8## wherein: X is halogen or OSO.sub.2 R, where R represents H or lower alkyl (with from one to four carbon atoms) optionally substituted with hydroxyl or amino groups, the amino groups being optionally substituted by one or two C.sub.1-4 alkyl groups;Y is NO.sub.2, NHOH, N.sub.3, NHR, NRR, N.dbd.NR, N(O)RR, NHSO.sub.2 R, N.dbd.NPhR, SR or SSR, where Ph is a benzene ring and R is defined as above, but that in the case where Y is N.dbd.NR or SSR, then R can also be another moiety of general formula I;W is selected from the structures of formulae (Ia, Ib or Ic): ##STR9## where E is --N.dbd. or --CH.dbd., G is O, S, or NH, and Q is either (a) absent or independently one to three of R, OR, NRR, NO.sub.2, CONHR, NHCOR, where R is independently as defined above or (b) is an additional group of formulae (Ia, Ib or Ic) and HET represents a 5- or 6-membered carbocycle or heterocycle containing one or two atoms selected from N, O and S;A and B collectively represent the fused benzene or 2-CO.sub.2 R pyrrole ring, where R is as defined above;or a physiologically functional derivative thereof.