Patent ID: 6183987
Filing Date: 2001-02-06
Classification: A61K,C07K,C12N

Abstract:
A method for producing bovine follicle stimulating hormone, said method comprising:introducing a first nucleic acid encoding an alpha subunit and a second nucleic acid encoding a beta subunit of bovine follicle stimulating hormone into an insect cell by means of at least one vector based on a baculovirus wherein at least one of said first and second nucleic acids contains at least one ATTTA sequence having a destabilizing effect on mRNA in a stretch of untranslated nucleotides at the at least one of said first and second nucleic acid's 3' end,culturing said resulting insect cell in a suitable medium thus producing bovine follicle stimulating hormone, andrecovering said thus produced bovine follicle stimulating hormone from said cultured medium.