Patent ID: 6548537
Filing Date: 2003-04-15
Classification: A61P,C07D

Abstract:
A compound having the structure Ib: where OR1 is selected from(i) a carboxylic ester, carbonate, or inorganic ester, having a central atom selected from carbon, sulfur, phosphorus, nitrogen, and boron, and having linked to said central atom at least one oxygen atom and at least one group â€”Yâ€”Z or â€”Oâ€”Yâ€”Z, where Y is a branched or unbranched C1-C6 alkyl or alkenyl chain, and Z is hydrogen or a polar group selected from keto, aldehyde, carboxylate, carboxylic ester, hydroxy, alkoxy, polyether, thiol, alkylthio, amino, ammonium, alkylamino, alkylammonium, cyano, nitro, sulfate, nitrate, phosphate, or a 5- to 7-membered heterocycle having ring atoms selected from carbon, nitrogen, oxygen, and sulfur, and three to six carbon ring atoms, and (ii) a mono-, di- or trisaccharide linked to C14 at an anomeric center; and OR3 is OH or Oâ€”(C&boxH;O)R, where R is lower alkyl.