Patent ID: 8617869
Filing Date: 2013-12-31
Classification: B82Y,C07K,C12N,G01N,H01L,H01M,Y02E

Abstract:
1. A nanoscale electrode comprising: a) a substrate surface having at least one area of gold deposited thereon; b) a multiplicity of genetically engineered Tobacco mosaic viruses TMV connected to the deposited gold, wherein the multiplicity of metallic coated TMV viruses are aligned and perpendicular to the substrate surface, wherein each of the genetically engineered Tobacco mosaic viruses comprises a multiplicity of virus coat protein subunits, wherein each of the subunits consists of a single recombinantly introduced cysteine residue inserted between amino acid residue two and three of U1 strain of TMV to be positioned at residue three at the amino terminus of the virus coat protein subunit having an amino acid sequence of SEQ ID NO. 1, and wherein the single recombinantly introduced cysteine residue engineered at a specific location at the N-terminus coat protein structure directs the end attachment of rod shaped TMV1cys particles through thiol interaction onto gold coated surfaces; and c) a metallic conductive coating deposited on and connected to the single recombinantly introduced cysteine residue of the subunits of the genetically engineered TMV1cys core thereby providing the nanoscale electrode that is uniformly coated.