Patent ID: 6077714
Filing Date: 2000-06-20
Classification: A61K,Y02A

Abstract:
A method for the prevention of unwanted scarring in surgical procedures comprising;implanting a selenium-carrier at a surgical site, said site having endogenous thiol compounds, wherein said selenium-carrier comprises (i) an organic selenium compound selected from the group consisting of RSeH, RSeR, RSeR', RSeSeR and RSeSeR', wherein R and R' are the same or different and each is an aliphatic residue containing at least one reactive group selected from the group consisting of aldehyde, amino, alcoholic, phosphate, sulfate, halogen, phenolic reactive groups and combinations thereof, attached to (ii) a carrier having a constituent which forms a bond with said reactive groups of said selenium compound to produce said selenium-carrier, for the localized generation of superoxide for localized inhibition of scar tissue formation at said site.