Patent ID: 6683200
Filing Date: 2004-01-27
Classification: A61K,A61P,C07C

Abstract:
An N-substituted-N substituted urea derivative represented by the following general formula I and a pharmaceutically acceptable salt thereof: wherein R1 represents a hydrogen atom, a lower alkyl group, an aryl group selected from the group consisting of phenyl substituted with a cycloalkyl group, and phenyl substituted with a phenyl group, or R1 represents a group represented by the following general formula II: wherein R2 represents a hydrogen atom, a lower alkyl group, a cycloalkyl group, an aryl group, a carboxyl group or an ester group, or R2 may form a ring together with R1; R3 and R4 may be the same or different and each represents a hydrogen atom, a lower alkyl group, a cycloalkylalkyl group, an arylalkyl group, a cycloalkyl group or an aryl group; R5 represents a hydrogen atom, a lower alkyl group, a hydroxyl group, a lower alkoxy group or an aryl group; R6 and R7 may be the same or different and each represents a hydrogen atom, a lower alkyl group, a cycloalkylalkyl group, a cycloalkyl group or an aryl group; A1 and A2 may be the same or different and each represents a lower alkylene group, provided that if both R6 and R7 are methyl groups, R1, R3 and R4 do not simultaneously represent hydrogen atom, or if R3 is an isopropyl group and both R6 and R7 are methyl groups, R1 does not represent an aryl group.