Patent ID: 9216208
Filing Date: 2015-12-22
Classification: A61K,A61P

Abstract:
1. A method of treatment of a posterior segment of eye disease selected from the group consisting of nonproliferative diabetic retinopathy, proliferative diabetic retinopathy, retinal neurodegeneration, retinal neovascularization, ischemia-induced retinopathy, retinopathy of prematurity, sickle-cell retinopathy, retinal vein occlusion, retinitis pigmentosa and combinations thereof, comprising: administering topically a therapeutically effective amount of somatostatin or a somatostatin analogue selected from the group consisting of somatostatin-28, somatostatin-14, somatostatin-13, prosomatostatin, octreotide, lanreotide, vapreotide, pasireotide, seglitide, cortistatin, and pharmaceutically acceptable salts thereof, by a topical ophthalmic composition selected from the group consisting of eye drops, ointments and unguents, wherein the concentration of the somatostatin or somatostatin analogue ranges between 1 μg/mL and 40 mg/mL, and wherein the composition is an isotonic aqueous solution, a poly(vinyl alcohol) aqueous solution, or mixtures thereof of pH between 3 and 8.