Patent ID: 8968765
Filing Date: 2015-03-03
Classification: A61L,C08G,Y10T

Abstract:
1. A brush polymer, comprising: (a) a linear polymer main chain; and (b) brush structural side chains, comprising: (b1) a hydrophobic molecular branch, wherein the hydrophobic molecular branch comprises polyurethane, and (b2) a hydrophilic molecular branch and an anti-biofilm or an anti-microbial molecular branch, wherein the anti-biofilm or the anti-microbial molecular branch comprises farnesol, xylitol, lactoferrin, ethylene diamine tetraacetic acid (EDTA), gallium, PNAG-degrading enzyme, RNA-III inhibiting peptide, furanone C30, silver, iodine, zinc, copper, an antibiotic, medicine or combinations thereof, wherein the linear polymer main chain is conjugated to the brush structural side chains by covalent bonds formed between a hydroxyl group and a reactive functional group, wherein the reactive functional group comprises: isocyanate, carboxyl, or epoxy, wherein the anti-biofilm or the anti-microbial molecular branch conjugates onto the linear polymer main chain by a covalent bond.