Patent ID: 6809203
Filing Date: 2004-10-26
Classification: A61P,C07D

Abstract:
A compound of the formula II: whereinR1 is selected from the group consisting of oxygen, sulfur and selenium; R2 is selected from the group consisting of -hydrogen; -alkyl; -alkyl-OH; -haloalkyl; -alkenyl; -alkyl-X-alkyl; -alkyl-X-alkenyl; -alkenyl-X-alkyl; -alkenyl-X-alkenyl; -alkyl-N(R5)2; -alkyl-N3; -alkyl-Oâ€”Câ€”(O)â€”N(R5)2; -heterocyclyl; -alkyl-X-heterocyclyl; -alkenyl-X-heterocyclyl; -aryl; -alkyl-X-aryl; -alkenyl-X-aryl; -heteroaryl; -alkyl-X-heteroaryl; -alkenyl-X-heteroaryl; â€”SO2CH3; and â€”CH2â€”Oâ€”C(O)â€”CH3; R3 and R4 are each independently: -hydrogen; -X-alkyl; -halo; -haloalkyl; â€”N(R5)2; or when taken together, R3 and R4 form a fused aromatic, heteroaromatic, cycloalkyl or heterocyclic ring; X is selected from the group consisting of â€”Oâ€”, â€”Sâ€”, â€”NR5â€”, â€”C(O)â€”, â€”C(O)Oâ€”, and a bond; and each R5 is independently H or C1-8alkyl.