Patent ID: 6419961
Filing Date: 2002-07-16
Classification: A61K

Abstract:
A sustained-release microcapsule comprising a bioactive substance obtained by encapsulating said bioactive substance in a homopolymer or copolymer of lactic acid/glycolic acid having a lactic acid/glycolic acid ratio of 100/0 to 50/50 mol %, and thermally drying the obtained microcapsule at a temperature ranging from the glass transition point of said homopolymer or copolymer of lactic acid/glycolic acid to a temperature up to 5Â° C. higher than the glass transition point of the homopolymer or copolymer of lactic acid/glycolic acid for about 24 to about 120 hours to produce a sustained-release microcapsule comprising relative to the weight of the sustained-release microcapsule, not less than 60% by weight of the homopolymer or copolymer of lactic acid/glycolic acid based on the weight of the microcapsule.