Patent ID: 6060604
Filing Date: 2000-05-09
Classification: A61P,C07C,C07D,C07F

Abstract:
A polyamine compound or a salt thereof, the polyamine compound having the structure: ##STR42## wherein: A is a spacer containing a chain having at least 2 atoms in the chain;R.sup.1 is hydrogen, hydrocarbon, heterosubstituted hydrocarbon, heteroaryl, heterosubstituted heteroaryl, or --L--(EAG).sub.a ;R.sup.2 is hydrogen, hydrocarbon, heterosubstituted hydrocarbon, heteroaryl heterosubstituted heteroaryl, or --L--(EAG).sub.b ;R.sup.3 is hydrogen, hydrocarbon, heterosubstituted hydrocarbon, heteroaryl, heterosubstituted heteroaryl, or --L--(EAG).sub.c ;R.sup.4 is hydrogen, hydrocarbon, heterosubstituted hydrocarbon, heteroaryl, heterosubstituted heteroaryl, or --L--(EAG).sub.d ;each L is independently a linker containing a linker chain having at least 1 atom in the chain;a, b, c, and d are each independently an integer not less than zero, with the sum of a, b, c, and d being no less than 2;each EAG is independently an electron-affinic group containing (i) a carbocyclic or heterocyclic aromatic moiety which contains a carbonyl, trifluoromethyl, halogen, nitro, nitroso, N-oxide, sulfonyl, sulfinyl, or phosphoryl group; (ii) a heterocyclic aromatic moiety which contains two heteroatoms; (iii) a metal complex; or (iv) an organo-metallic group which contains a metal covalently bonded to carbon; andthe compound or salt contains at least one tertiary amine functionality having three substituents each of which independently contain at least one electron-affinic group or hydrophilic group.