Patent ID: 7473792
Filing Date: 2009-01-06
Classification: B01J,C07B,C07C

Abstract:
1. A process for transition metal-catalyzed asymmetric hydrogenation of acrylic acid derivatives of the formula (I) in which R1 is H or an optionally substituted C in which Cn, together with the two oxygen atoms and the phosphorus atom, forms an optionally substituted ring having from 2 to 6 carbon atoms and R4 is an optionally substituted alkyl, aryl, alkoxy or aryloxy radical or NR5R6 where R5 and R6 may each independently be H or an optionally substituted alkyl, aryl, aralkyl or alkaryl radical, or, together with the nitrogen atom, may form a ring, and an achiral phosphine ligand of the formula (III) in which R is an optionally substituted alkyl or aryl radical, to the corresponding compounds of the formula (IV) in which R1, R2 and R3 are each as defined above.