Patent ID: 8968561
Filing Date: 2015-03-03
Classification: B01D

Abstract:
1. A preparative separation/purification system, comprising: a source of a sample-introducing solvent which is an organic solvent or a mixture of the organic solvent and water; a source of an additive agent having a higher polarity than that of the organic solvent of the sample-introducing solvent; a trapping passage including a trap column; a solution supply means for sending, to the trapping passage, a solution having a captured target component from a liquid sample dissolved in a sample-introducing solvent which is the organic solvent or the mixture of the organic solvent and water; a diluting liquid supply passage for merging a diluting liquid into the solution at a point before the trap column in the trapping passage in order to lower an elution capability of the sample-introducing solvent; a diluting liquid supply means, provided in the diluting liquid supply passage, for supplying the diluting liquid; and an additive-mixing means for mixing into the diluting liquid the additive agent having the higher polarity than that of the organic solvent of the sample-introducing solvent for preventing the target component and a foreign compound in the solution from precipitating due to a decrease in a solubility of target component and the foreign compound in the sample-introducing solvent occurring with lowering of the elution capability of the solvent caused by a mixture of the diluting liquid.