Patent ID: 7678823
Filing Date: 2010-03-16
Classification: A61K,A61P,C07D,C07F

Abstract:
1. A compound of Formula II, a pharmaceutically acceptable salt thereof, or a pharmaceutical composition having such a compound, Wherein one of R2 and R4 is —COOH, while the other is —H; R1, R3, and R5, independent of one another, are chosen from hydro, hydroxyl, halo, alkyl, alkoxy, haloalkyl, haloalkoxy, —N(C 1-3 alkyl) 2 , —NH(C 1-3 alkyl), —C(═O)NH 2 , —C(═O)NH(C 1-3 alkyl), —C(═O)N(C 1-3 alkyl) 2 , —S(═O) 2 (C 1- 3 alkyl), —S(═O) 2 NH 2 , —S(═O) 2 N(C 1-3 alkyl) 2 , —S(═O) 2 NH(C 1-3 alkyl), —CHF 2 , —OCF 3 , —OCHF 2 , —SCF 3 , —CF 3 , —CN, —NH 2 , and —NO 2 ; R6 is hydro; one of R7, R8 or R9 is haloalkyl, while the other two are, independent of one another, chosen from hydro, hydroxyl, halo, alkyl, alkoxy, haloalkyl, haloalkoxy, —N(C R10 is hydro; and R11 is an optionally substituted phenyl or heterocyclic group.