Patent ID: 6747031
Filing Date: 2004-06-08
Classification: A61P,C07D

Abstract:
A compound of formula (Ya), formula (Yb) or formula (Yc): wherein:n and m are independently an integer from 1 to 4; A is â€”C(O)OR1 or â€”C(O)N(R1)R2; each W is N or CH; each R1 is independently hydrogen, alkyl, aryl or aralkyl; each R2 is independently hydrogen, C1-C20 alkyl, â€”(CH2)nâ€”N(R1)2, heterocyclylalkyl (optionally substituted by alkyl, halo, haloalkyl or alkoxy), aralkyl (optionally substituted by halo, alkyl, alkoxy, or â€”N(R1)2); when m is an integer from 2 to 4, R4 can be hydroxy, â€”N(R1)R2, â€”N(R1)â€”C(O)â€”R1, â€”N(R1)â€”C(O)OR1, â€”N(R1)â€”S(O)tâ€”R1, or â€”N(R1)â€”C(O)â€”N(R1)2; when m is an integer from 1 to 4, R4 can also be cyano or heterocyclyl; R5 is hydrogen, halo, alkyl, aryl, aralkyl, or haloalkyl; and t is zero, one or two; as a single stereoisomer or mixture thereto, or a pharmaceutically acceptable salt thereof.