Patent ID: 6017718
Filing Date: 2000-01-25
Classification: G01N

Abstract:
A method for predicting the presence of deep venous thrombosis in a patient, comprising the steps of:a) obtaining a sample of urine from the patient;b) measuring the concentration of soluble tumor necrosis factor receptor-1 in the sample;c) comparing the concentration of soluble tumor necrosis factor receptor-1 in the sample to an established baseline concentration of soluble tumor necrosis factor receptor-1, wherein said established baseline concentration of soluble tumor necrosis factor receptor-1 is at least 10 picograms/milliliter to about 500 picograms/milliliter of urine and wherein a measured concentration of soluble tumor necrosis factor greater than the established baseline concentration is predictive of the presence of deep venous thrombosis in the patient; andd) predicting the presence of, or development of, deep venous thrombosis in the patient if the concentration of soluble tumor necrosis factor receptor-1 in the sample is greater than the established baseline concentration of soluble tumor necrosis factor receptor-1.