Patent ID: 6346518
Filing Date: 2002-02-12
Classification: A61K,Y10S

Abstract:
A stereoisomeric form of itraconazole selected from the group consisting of:(âˆ’)-[2S-[2&agr;,4&agr;,4(S)]]-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmetyl) -1,3-dioxolan-4-yl]methcoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl) -3H-1,2,4-triazol-3-one; and (âˆ’)-[2S-[2&agr;,4&agr;,4(R)]]-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl) -1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one.