Patent ID: 7125715
Filing Date: 2006-10-24
Classification: A61K,A61P,C07K,C12N

Abstract:
1. An isolated polynucleotide encoding a polypeptide selected from: (a) a polypeptide consisting of an amino acid sequence consisting of amino acids 23 to 388 of SEQ ID NO:2; (b) a polypeptide consisting of an amino acid sequence consisting of amino acids 1 to 388 of SEQ ID NO: 2; (c) a polypeptide comprising an amino acid sequence consisting of amino acids 23 to 388 of SEQ ID NO: 2, and exhibiting an activity of promoting type II collagen production and/or an activity of promoting aggrecan production; or (d) a polypeptide according to any one of (a), (b), or (c), exhibiting both an activity of promoting type II collagen production and an activity of promoting aggrecan production.