Patent ID: 6156002
Filing Date: 2000-12-05
Classification: A61M

Abstract:
Method of determining mass transfer in hemodialysis and hemodiafiltration using a dialyzer separated into a blood compartment and a dialysate compartment by a semipermeable membrane comprising a fluid circuit on the bloodside connected to a patient or a source of liquid and to discharge and a liquid circuit on the dialysate side connected to a source of liquid (dialysate, water) and to discharge and having at least one sensor downstream of the dialyzer in the dialysate circuit and means for the addition of a substance upstream of the dialyzer in the dialysate circuit of which the mass transfer properties are measured, said method comprising the steps of measuring in a first time interval the basic concentration of said substance downstream of the dialyzer, adding said substance upstream of the dialyzer as a bolus during a second time interval, and calculating the dialysance from the amount of substance added upstream, the integral of the substance concentration minus the basic concentration over time downstream of the dialyzer, and the dialysate flow.