Patent ID: 8623876
Filing Date: 2014-01-07
Classification: A61P,C07D

Abstract:
1. A method for treating a disease selected from the group consisting of ovarian cancer, breast cancer, colon cancer, lung cancer, small cell lung cancer, pancreatic cancer, cervical cancer, prostate cancer, skin carcinoma, squamous cell carcinoma, hematopoietic tumors of lymphoid lineage, leukemia, acute lymphocitic leukemia, acute lymphoblastic leukemia, B-cell lymphoma, T-cell-lymphoma, Hodgkin's lymphoma, non-Hodgkin's lymphoma, hairy cell lymphoma, Burkett's lymphoma, hematopoietic tumors of myeloid lineage, acute myelogenous leukemia, chronic myelogenous leukemia, myelodysplastic syndrome, promyelocytic leukemia melanoma and osteosarcoma which comprises administering to a mammal in need thereof an effective amount of a compound of formula (I): wherein: R is hydrogen or an optionally further substituted group selected from: saturated or unsaturated, straight or branched C A is CH Ar is an optionally substituted aryl, provided that when A is CH when A is CH isomers, tautomers, metabolites, prodrugs, carriers, N-oxides and pharmaceutically acceptable salts thereof.