Patent ID: 9168398
Filing Date: 2015-10-27
Classification: A61K,A61Q

Abstract:
1. An arbutin-containing composition comprising: arbutin in an amount from about 5% to about 10% by weight of the total composition; a preservative in an amount from about 0.01 to about 5% by weight of the total composition; a chelating agent in an amount from about 0.01 to about 5% by weight of the total composition; a humectant in an amount from about 1 to about 20% by weight of the total composition; an emulsifier in an amount from about 1 to about 20% by weight of the total composition; a pH adjustment agent in an amount from about 0.01 to about 5% by weight of the total composition; and a reducing agent in an amount from about 0.1 to about 10% by weight of the total composition, wherein the composition is at least 85% as efficacious with regard to skin lightening, when used alone or in a system as measured by Chromameter® b* parameter values as a substantially corresponding composition containing hydroquinone in an amount from about the same molar amount to about 1.5 times the molar amount of arbutin.