Patent ID: 7361517
Filing Date: 2008-04-22
Classification: C07K,G01N,Y10S

Abstract:
1. A method for diagnosing an acute inflammatory episode of systemic lupus erythematosus (SLE) in an individual, the method comprising: (a) isolating reticulocytes from a blood sample of an individual; (b) determining the level of a C4d complement pathway component on the isolated reticulocytes from the individual, and (c) comparing the C4d complement pathway component level on the isolated reticulocytes from the individual with a control level of C4d complement pathway component on reticulocytes, wherein an elevated level of the C4d complement pathway component on the isolated reticulocytes in the individual compared to the control level of the C4d complement pathway component on reticulocytes indicates that the individual has the acute inflammatory episode of SLE.