Patent ID: 8703118
Filing Date: 2014-04-22
Classification: A61L,A61M,A61P

Abstract:
1. A process for preparing an injectable composition useful for correcting mammary hypoplasia, the process comprising: forming a first composition by contacting a hyaluronic acid (HA) solution comprising HA with a cross-linker to allow cross-linking of the HA by the cross-linker; homogenizing the first composition; forming a second composition by contacting the first composition with collagen solution comprising collagen to allow cross-linking of the collagen by the cross-linker to the first composition, wherein the second composition has a cross-linked HA core with a layer of collagen surrounding and cross-linked to the cross-linked HA core; and forming a tri-layer composition by contacting the second composition with a HA in a solution comprising HA to allow cross-linking of the HA by the cross-linker to the second composition, wherein the tri-layer composition has a cross-linked HA core, a middle layer of collagen layer surrounding and cross-linked to the cross-linked HA core, and an outer layer of HA surrounding and cross-linked to the middle layer of collagen; homogenizing the tri-layer composition to form an injectable composition useful for correcting the mammary hypoplasia.