Patent ID: 7205114
Filing Date: 2007-04-17
Classification: B82Y,C07K,G01N

Abstract:
1. A method of testing a sample to determine the presence and/or amount of an antibody to a fungal antigen, the method comprising: a) contacting the fungal antigen with an oxidizing agent in a suitable device to produce an oxidized fungal antigen attached to the surface of the device, wherein said oxidized fungal antigen attached to said device is suitable for testing an antibody to the fungal antigen; b) contacting a sample suspected of containing an antibody to a fungus with the device containing the attached oxidized fungal antigen produced in step b) under suitable conditions to allow binding of the antibody, if present in the sample, to the oxidized fungal antigen; and c) assessing binding between the antibody and the oxidized fungal antigen to determine the presence and/or amount of the antibody in the sample.