Patent ID: 6589949
Filing Date: 2003-07-08
Classification: A61P,C07D

Abstract:
A compound of the general formula (I), in whichR1 and R2 are identical or different and independently of one another represent hydrogen, halogen, (C1-C6)-alkyl, (C1-C6)-alkoxy, (C1-C3)-perfluoroalkyl, (C1-C3)-perfluoroalkoxy or a radical â€”NR5R6, â€ƒin which R5 and R6 are identical or different and represent hydrogen, (C1-C4)-alkyl, (C1-C4)-acyl, (C1-C4)-alkoxycarbonyl, carbamoyl, mono- or di-(C1-C4)-alkylaminocarbonyl, R3 and R4 are identical or different and independently of one another represent (C1-C8)-alkyl whose carbon chain is optionally interrupted by an oxygen or sulfur atom or by a radical NR7 and which is optionally mono- or polysubstituted by radicals selected from the group consisting of (C3-C6)-cycloalkyl, (C1-C4)-alkoxy, hydroxyl, halogen or NR8R9, represent (C3-C8)-cycloalkyl whose carbon chain is optionally interrupted by an oxygen or sulfur atom or by a radical NR10 and which is optionally mono- or polysubstituted by radicals selected from the group consisting of (C1-C4)-alkoxy, hydroxyl, halogen or NR11R12, â€ƒin which R7, R8, R9, R10, R11 and R12 are identical or different and independently of one another have the meaning mentioned for R5, or R3 and R4, together with the nitrogen atom, form a saturated or partially unsaturated 3- to 10-membered, mono- or bicyclic heterocycle, which optionally contains up to two further heteroatoms selected from the group consisting of nitrogen, oxygen or sulfur, and which is optionally substituted by radicals selected from the group consisting of (C1-C4)-alkyl, (C1-C4)-alkoxy, hydroxyl, halogen, COOR13 or NR14R15, â€ƒin which R13 denotes hydrogen or (C1-C4)-alkyl, and R14 and R15 are identical or different and independently of one another have the meaning mentioned for R5, and X represents oxygen or sulfur, and its salts.