Patent ID: 6361806
Filing Date: 2002-03-26
Classification: A61K,Y10S

Abstract:
An emollient composition for topical administration of a safe and effective dosage of a C18 unsaturated fatty acid to a subject in need thereof, comprising a carrier, a vehicle, a penetrant, a mixture of C16 and C20 fatty acids in a hydrophobic phase with said C18 unsaturated fatty acid, a natural anti-inflammatory compound, a natural estrogenic compound and a fragrance, wherein:said C18 unsaturated fatty acid is selected from the group consisting of a C18:1 fatty acid, a C18:2 fatty acid, a C18:3 fatty acid and unsaturated derivatives and mixtures thereof; said emollient composition comprises greater than about 3% by weight of said C18 unsaturated fatty acid; said vehicle comprises water, ethanol, propylene glycol and glycerin; said penetrant is selected from the group consisting of urea, imidurea, palmitate, isopropyl palmitate, isoproyl myristate, propylene glycol and nonionic detergents; said C16 and C20 fatty acids are selected from the group consisting of C16:0, C16:1, C20:3, C20:4 and derivatives and mixtures thereof; said natural anti-inflammatory compound is selected from the group consisting essentially of herbal anti-inflammatory compounds include unpurified and substantially purified oils collected from a Chamomilla species, a Matricaria species, an Artemisia species, an Achillea species and species genetically related thereto; and, said natural estrogenic agent comprises an alkyl-hydroxy-benzoate compound capable of stimulating estrogen synthesis in an adipose tissue.