Patent ID: 9073979
Filing Date: 2015-07-07
Classification: A61K,A61P,C07K,C12N

Abstract:
1. A composition comprising: a genomic nucleic acid molecule comprising a replicative full-length copy of a Marek's Disease Virus-1 (MDV-1) herpesvirus genome, except in that the US2 coding sequence of the MDV-1 herpesvirus genome is replaced by a bacterial artificial chromosome (BAC) vector; wherein said genomic nucleic acid molecule is capable of replication in a eukaryotic host cell; wherein said genomic nucleic acid molecule encodes infectious MDV-1 herpesvirus when the genomic nucleic acid molecule is expressed in a host cell; and wherein said BAC vector allows for recombination of the genomic nucleic acid in a bacterium.