Patent ID: 6153175
Filing Date: 2000-11-28
Classification: A61K,A61Q,C07C

Abstract:
Compounds of the formula ##STR10## wherein R.sup.1 to R.sup.4, R.sup.3', R.sup.3"", R.sup.4' and R.sup.4"" independently of one another denote hydrogen, C.sub.1 -C.sub.8 -alkyl or C.sub.5 -C.sub.10 -cycloalkyl, with the proviso that two substituents on adjacent C atoms together can also denote an optionally substituted C.sub.1 -C.sub.4 -alkylene group, in which a methylene group may be replaced by --O--, --S-- or --NH--, and furthermore independently of one another denote C.sub.1 -C.sub.4 -alkoxy, hydroxyl, carboxyl, carbalkoxy or carbamoyl,R.sup.5 to R.sup.8 independently of one another have the meaning of R.sup.1, R.sup.2 or sulpho or aminosulphonyl,X and Y independently of one another denote CN, CO.sub.2 R.sup.9, CO.sub.2 NR.sup.9 R.sup.10 or COR.sup.9, wherein R.sup.9 and R.sup.10 independently of one another represent hydrogen, C.sub.1 to C.sub.8 -alkyl or C.sub.5 -C.sub.10 -cycloalkyl, and furthermore one of the radicalsX or Y can additionally denote a C.sub.1 -C.sub.8 -alkyl radical, a C.sub.5 -C.sub.10 -aryl radical, or a 5- to 6-membered heteroaryl radical which contains 1 or 2 heteroatoms selected from the group consisting of N, O and S, orX and Y, together with the .beta. atom to which they are bonded, denote a 5- to 7-membered ring which contains up to 3 heteroatoms selected from the group consisting of oxygen and nitrogen, substituted by exocyclically double-bonded oxygen (keto group) andn and m independently of one another denote zero or 1, with the exception of compounds of the formula ##STR11## wherein R.sub.1, R.sub.2 and R.sub.3 in each case independently of one another can be identical or different and denote a hydrogen atom, halogen atom, hydroxyl group, nitro group, cyano group or monovalent, optionally substituted organic radical andR.sub.4 denotes hydrogen, a halogen atom, nitro group, cyano group or monovalent, optionally substituted organic radical andR.sub.5 can be identical or different and denotes a halogen atom, hydroxyl group, nitro group, cyano group or monovalent, optionally substituted organic radical and with the exception of ##STR12##