Patent ID: 6020502
Filing Date: 2000-02-01
Classification: C07B,C07C,C07D

Abstract:
A method for the production of 1,3-diketones and 1,3-ketoesters having a formula selected from the group consisting of (1), (2) and (3) as follows: ##STR4## which comprises converting a corresponding compound having a formula selected from the group consisting of (5), (6), (7) and (8) as follows: ##STR5## into compounds of formula (1), (2), (3) or (4) by reaction with elemental fluorine, wherein R.sub.1 is selected from the group consisting of alkyl, substituted alkyl, cycloalkyl, aryl, substituted aryl and acetoxy, R.sub.2 is selected from the group consisting of hydrogen, halogen, nitro, cyano, alkyl, cycloalkyl, acetoxy and aryl substituted alkyl, acetoxy, aryl and substituted aryl, and R.sub.3 is selected from the group consisting of alkyl, substituted alkyl, oxyalkyl and substituted oxyalkyl, R.sub.4 and R.sub.5 are hydrogen or alkyl, n is an integer in the inclusive range of 1 to 8 and the structures represented by formula (2), (3), (4), (6), (7) and (8) are cyclic, the process being carried out by passing fluorine gas into a solution of the appropriate compound of formula (5), (6), (7) or (8) in a substantially inert solvent comprising an acid having a pH<7 wherein said solvent comprises formic acid.