Patent ID: 7566566
Filing Date: 2009-07-28
Classification: A61K,A61P,C07K,C12N

Abstract:
1. A method of modulating the growth of mammalian endothelial cells or mammalian endothelial precursor cells, comprising the step of contacting the cells with a polypeptide in an amount effective to modulate the growth of mammalian endothelial cells, wherein the polypeptide comprises an amino acid sequence at least 95% identical to a chimeric vascular endothelial growth factor amino acid sequence of the formula: wherein X wherein X wherein X wherein X wherein X wherein X wherein X wherein X wherein X wherein NH wherein the polypeptide binds to at least one receptor selected from the group consisting of human VEGFR-1, human VEGFR-2, and human VEGFR-3.