Patent ID: 8716234
Filing Date: 2014-05-06
Classification: A61K,A61P,C07K

Abstract:
1. A method of inhibiting or destroying a lymphoma cancer cell comprising administering a cytotoxin to an animal having lymphoma, wherein said cytotoxin comprises a targeting moiety that binds to the lymphoma cancer cell and is linked to a modified bouganin protein, wherein said modified bouganin protein comprises: YNTVSFNLGEAYEYPTFIQDLRNELAKGTPVCQLPVTLQTIADDKRFVLVDITT TSKKTVKVAIDVTDVYVVGYQDKWDGKDRAVFLDKVPTVATSKLFPGVTNRVTLTFD GSYQKLVNAAKX wherein at least one of X wherein, when substituted, X wherein, when substituted, X wherein, when substituted, X wherein, when substituted, X wherein, when substituted, X wherein, said modified bouganin protein has ribosome inactivating activity.