Patent ID: 6228877
Filing Date: 2001-05-08
Classification: A61P,C07D

Abstract:
A compound of the formula ##STR19##whereinR.sup.1 and R.sup.1' are independently alkyl, aryl, alkenyl or alkynyl;R.sup.2 and R.sup.2' are independently hydrogen or alkyl;R.sup.4, R.sup.5, R.sup.7, R.sup.4', R.sup.5', and R.sup.7' each are hydrogen,R.sup.6 and R.sup.6' are independently nitro, alkoxy, alkyl, halogen, cyano, ##STR20##CO.sub.2 R.sup.9, CH.sub.2 OR.sup.10, CHO, CH.sub.2 NR.sup.11 R.sup.12, CON(R.sup.13).sub.2, alkylthio or aralkyloxy;R.sup.8 is alkyl or aryl;R.sup.9 is alkyl or aryl;R.sup.10 is hydrogen, alkyl or aryl;R.sup.11 and R.sup.12 are independently hydrogen, alkyl, aryl, aralkyl or acyl;R.sup.13 is hydrogen, alkyl, aryl or aralkyl; andone of X and Y signifies O and the other signifies O, S, (H,OH) or (H,H); or a pharmaceutically acceptable salt of an acidic compound of formula I or a pharmaceutically acceptable salt of a basic compound of formula I whereinalkyl contains a maximum of 10 carbon atoms;alkenyl contains 2 to 5 carbons;acyl contains a maximum of 10 carbon atoms, andaryl is an unsubstituted phenyl group or a phenyl group substituted by one, two or three substituents which substituents are independently halogen, alkyl, hydroxy, benzyloxy, alkoxy, haloalkyl, nitro, amino or cyano.