Patent ID: 6569149
Filing Date: 2003-05-27
Classification: A61N,C12M

Abstract:
A method for the application of electric fields to a tissue of a patient having a cell proliferation disorder for the purpose of introducing molecules into cells of the tissue to treat the cell proliferation disorder, comprising:providing an array of multiple opposed pairs of electrodes connected to a generator, wherein at least two pairs of electrodes are activated simultaneously; positioning at least a first pair and at least a second, opposed pair of electrodes of said array of electrodes in conductive relation to the tissue so that the tissue is between said first and second opposed pairs of electrodes; introducing molecules into the tissue; and separately applying electric pulses to the at least two different pairs of electrodes, but not all electrodes simultaneously, wherein the strength of the electric pulses is sufficient to produce an electric field in the tissue that causes the molecules to enter cells of the tissue and wherein the molecules are introduced into the tissue substantially contemporaneously with application of the electric pulses to the electrodes.