Patent ID: 8277838
Filing Date: 2012-10-02
Classification: A61K,A61P

Abstract:
1. A transdermal drug delivery system comprising a pressure sensitive adhesive composition which comprises a blend of: (a) one or more polymers selected from the group consisting of a rubber based polymer, an acrylic based polymer and a polysiloxane; and (b) a pharmacologically effective amount at least one drug for transdermal drug delivery, wherein said at least one drug is (i) solubilized in said pressure sensitive adhesive, (ii) incorporated in said pressure sensitive adhesive in crystal form having a small crystal size, and (iii) incorporated in said pressure sensitive adhesive in crystal form having a larger crystal size, wherein the amount of drug solubilized in said pressure sensitive adhesive, the amount of drug incorporated in said pressure sensitive adhesive in crystal form having a small crystal size, and the amount of drug incorporated in said pressure sensitive adhesive in crystal form having a larger crystal size are selectively tailored to control the drug delivery rate and profile of the drug from the transdermal drug delivery system.