Patent ID: 6596274
Filing Date: 2003-07-22
Classification: A61K,A61L,C12N

Abstract:
A biological material comprising the following two components:(a) a first component comprising: (1) a culture of autologous or homologous bone marrow stem cells partially or completely differentiated into cellular lines of a specific connective tissue selected from the group consisting of fibroblasts, osteoblasts, myoblasts, adipocytes, chondrocytes and endothelial cells and an extracellular matrix produced by the specific connective tissue cellular lines, or, alternatively (2) a sole extracellular matrix free from any cellular component secreted by said specific connective tissue cellular lines resulting from partially or completely differentiated bone marrow stem cells, or secreted by specific mature connective tissue cells selected from the group consisting of fibroblasts, osteoblasts, myoblasts, adipocytes, chondrocytes and endothelial cells; and (b) a second component comprising a three-dimensional biocompatible and biodegradable matrix consisting of a hyaluronic acid ester having a degree of esterification comprised between 25 and 100%.