Patent ID: 9089593
Filing Date: 2015-07-28
Classification: A61K,A61P

Abstract:
1. A method of stabilizing or regressing a tumor in a patient comprising the steps of: collecting monocyte cells from the patient afflicted with the tumor, said tumor selected from the group consisting of lung cancer, colon cancer, and liver cancer; culturing the monocyte cells with IL-4 and GM-CFS to form immature dendritic cells from the monocyte cells; combining the immature dendritic cells and a leukocyte cultured medium (LCM) adjuvant to form a composition; and administering a therapeutically effective amount of the composition to the patient, said LCM adjuvant comprising at least three cytokines selected from the group consisting of eotaxin, FGF, G-CSF, GM-CSF, IFNγ, IP10, IL1β, IL1ra, IL2, IL4, IL5, IL6, IL7, IL8, IL9, IL10, IL12, IL13, IL15, IL17, MCP1, MIP1α, MIP1β, PDGFbb, RANTES, TNFα, and VEGF, wherein said composition of immature dendritic cells and LCM adjuvant is administered intratumorally.