Patent ID: 6160122
Filing Date: 2000-12-12
Classification: C07D

Abstract:
A process for the preparation of a compound of the formula: ##STR7## wherein R.sub.1 is hydrogen, loweralkyl, alkoxyalkyl, hydroxyalkyl, cycloalkyl, cycloalkylalkyl, aryl or arylalkyl, or a salt thereof comprising reacting N-methyl-N-((2-isopropyl-4-thiazolyl)methyl)amine with a compound of the formula: ##STR8## wherein R is selected from the group consisting of hydrogen, loweralkyl, halo, haloalkyl, alkenyloxy, alkoxy, alkoxyalkoxy, alkoxycarbonyl, thioalkoxy, dialkylamino, nitro, carboxaldehyde and cyano and R.sub.1 is defined as above, in the presence of a base selected from the group consisting of sodium hydride, lithium hydride, sodium hydroxide, lithium hydroxide, sodium phenoxide and lithium phenoxide.