Patent ID: 6486232
Filing Date: 2002-11-26
Classification: A61B,A61F,A61L

Abstract:
A multi-part bioerodible bone cement system comprising two or more separate parts which, upon mixing of the system parts, forms a bioerodible polymeric semi-IPN alloy, wherein a first said part comprises a first bioerodible polymer capable of producing acidic products upon hydrolytic degradation and one of said parts, which may be the same as or different from said first part, comprises a second bioerodible scaffolding polymer which upon crosslinking provides a biopolymeric scaffolding or internal reinforcement for said semi-IPN alloy; wherein one of said parts comprises crosslinking initiator and one of said parts comprises a crosslinking agent for said second bioerodible scaffolding polymer, wherein said crosslinking agent and said crosslinking initiator are in separate parts; wherein one of said parts comprises a therapeutically effective amount of a biologically active or therapeutic agent in a protective coating of a bioerodible polymer; and wherein, further, at least one of said parts comprises only dry components, at least one of said parts comprises liquid components and said biologically active or therapeutic agent is in a said part comprising only said dry components.