Patent ID: 6919437
Filing Date: 2005-07-19
Classification: C07H

Abstract:
1. A compound having the formula: wherein: each B is, independently, a naturally occurring or non-naturally occurring nucleobase; each R each R each R each X is, independently, O or S; R z is 0 or 1; x R R R R wherein: each X is, independently, O or S; Z n is 1 to about 100; m is 1 to about 100; and R wherein: provided that at least one of x 1 and x 2 is not 1 when R 3 is hydrogen or a hydroxyl protecting group and z is 0, and provided that at least one nucleoside is a β-nucleoside and bound at its 3′ position to a linking group of formula —O—P(X)(R n )—O— or —O—P(X)(R m )—O— where R n or R m is O − or —O—(CH 2 ) p2 —E.