Patent ID: 6320085
Filing Date: 2001-11-20
Classification: C07C,C07D

Abstract:
A process for the preparation of mixed ethers of general formula I: ##STR2##whereinAr represents an aromatic or one or more heteroatom-containing moiety, optionally substituted by one or more C.sub.1-4 alkoxy, methylenedioxy, C.sub.1-4 alkyl, halogen, C.sub.1-4 haloalkyl or nitro-group, and/or condensed with a benzene ring; R.sub.1 and R.sup.2 independently mean hydrogen, C.sub.1-4 alkyl, C.sub.1-4 haloalkyl, C.sub.2-4 alkenyl, phenyl, substituted phenyl, C.sub.3-6 cycloalkyl group;R.sub.3 means C.sub.3-6 alkynyl, optionally substituted by one or more C.sub.1-6 alkyl, C.sub.3-6 alkenyl, C.sub.3-6 alkynyl, C.sub.1-6 haloalkyl group, or halogen atom, R.sub.3 also means a C.sub.1-4 alkyloxy-C.sub.1-4 alkyloxy-C.sub.1-4 alkyl group;comprising the step of:reacting the compounds of general formula II with 1 to 3 molar equivalent of the alcohol of general formula III in the presence of acid, a Lewis acid, a metal oxide or a metal carbonate; ##STR3##isolating the resulting ether of general formula III; andoptionally, stabilizing the resulting ether of general formula III by the addition of a base and/or an antioxidant; andwherein,X means hydroxy, halogen or sulphonester leaving group.