Patent ID: 6350775
Filing Date: 2002-02-26
Classification: A61P,C07D

Abstract:
A compound of formula (I): whereinR1 is hydroxy or of the formula â€”NHC(&boxH;O)(1-4C)alkyl or â€”NHS(O)n(1-4C)alkyl wherein n is 0, 1 or 2; R2 and R3 are independently hydrogen or fluoro; R4 and R5 are independently hydrogen or methyl; >Aâ€”Bâ€” is of the formula >C&boxH;CHâ€”, or >C(OH)CH2â€”; >Xâ€”Yâ€” is of the formula >C&boxH;CHâ€”, or >CHCH2â€”; and D is S, SO, or SO2; or a pharmaceutically-acceptable salt thereof.