Patent ID: 7122565
Filing Date: 2006-10-17
Classification: A61P,C07D

Abstract:
1. A compound of Formula 1: wherein: Y is S; R  each optionally substituted with one or several groups of the formula X R  each optionally substituted with one or several groups which are the same or different and which are: 1) H, carboxylic acid bioisostere, lower haloalkyl, halogen, 2) COOR 3) SO R R  each optionally substituted with one or several groups which are the same or different and which are: R  in which X R 1-Phenyl-1-[4-phenyl-5-(5-trifluoromethyl-2H-[1,2,4]triazol-3-ylimino)-4,5-dihydro-[1,3,4]thiadiazol-2-yl]-methanone, 1-[4-Phenyl5-(5-trifluoromethyl-2H-[1,2,4]triazol-3-ylimino)-4,5-dihydro-[1,3,4]thiadiazol-2-yl]-1-thiophen-2-yl-methanone, 1-Phenyl-1-(4-phenyl-5-p-tolylimino-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-methanone, Cyclohexyl-[3-(2,4,6-trichloro-phenyl)-5-(2,3,3-trimethyl-cyclopent-1-enylmethyl)-3H-[1,3,4]thiadiazol-2-ylidene]-amine, 2-(3,5-Diphenyl-3H-[1,3,4]thiadiazol-2-ylideneamino)-1,4-diphenyl-but-2-ene-1,4-dione, 2-[3-Phenyl-5-(1-phenyl-methanoyl)-3H-[1,3,4]thiadiazol-2-ylideneamino]-but-2-enedioic acid dimethyl ester, 2-[5-(1-Phenyl-methanoyl)-3-p-tolyl-3H-[1,3,4]thiadiazol-2-ylideneamino]-but-2-enedioic acid dimethyl ester, and 2-[3-(4-Chloro-phenyl)-5-(1-phenyl-methanoyl)-3H-[1,3,4]thiadiazol-2-ylideneamino]-but-2-enedioic acid dimethyl ester.