Patent ID: 7101911
Filing Date: 2006-09-05
Classification: A61P,C07C

Abstract:
1. A compound of the formula I in which M is the central building block where R1 is carboxyl, 1–4C-alkoxycarbonyl or hydroxy-1–4C-alkyl, A1 is —O—B1-A3-, -A5-B1-O—, —C(O)—, —C(O)—NH—, —NH—C(O)—, —O—C(O)—NH—, —NH—C(O)—O—, —NH—C(O)—NH— or —O—C(O)—O—, A2 is —O—B2-A4-, -A6-B2-O—, —C(O)—, —C(O)—NH—, —NH—C(O)—, —O—C(O)—NH—, —NH—C(O)—O—, —NH—C(O)—NH— or —O—C(O)—O—, A3 and A4 are identical or different and are —C(O)—, —C(O)—NH—, —NH—C(O)—, —O—C(O)—NH—, —NH—C(O)—O—, —NH—C(O)—NH— or —O—C(O)—O—, A5 and A6 are identical or different and are —C(O)—, —C(O)—NH—, —NH—C(O)—, —O—C(O)—NH—, —NH—C(O)—O—, —NH—C(O)—NH— or —O—C(O)—O—, B1 and B2 are identical or different and are 1–4C-alkylene, K1 is -B3-X1, -B3-Y1 or -B3-Z1-B5-X1, K2 is -B4-X2, -B4-Y2 or -B4-Z2-B6-X2, B3 and B4 are identical or different and are a bond or 1–4C-alkylene, B5 and B6 are identical or different and are a bond or 1–2C-alkylene, X1 and X2 are identical or different and are amino, aminocarbonyl or amidino, Y1 and Y2 are imidazol-1-yl, Z1 and Z2 are identical or different and are 5,2-pyridinylene, 6-methyl-5,2-pyridinylene, 4,1-piperidinylene, 3,6-indazolylene, 3,6-indolylene, 1,3-phenylene, 1,4-phenylene, 1,3-cyclohexylene or 1,4-cyclohexylene, and where on the direct route between the terminal nitrogen atoms, 20 to 35 bonds have to be present, or a solvate, hydrate, salt, hydrate of a salt or solvate of a salt of the compound, or an N-oxide of a nitrogen-containing heteroaryl, heteroarylene or heterocycloalkylene, or a solvate, hydrate, salt, hydrate of a salt or solvate of a salt of the N-oxide, where all those compounds are excluded in which one or more of the variables B3, B4, B5 and B6 can have the meaning of a bond, resulting in the direct linkage of two heteroatoms.