Patent ID: 6034139
Filing Date: 2000-03-07
Classification: A01N,A61K,C07C,C07D

Abstract:
A method of treating a human or non-human animal in need of anti-neoplastic therapy and afflicted with malignant tumor cells sensitive to a polyamine having the formula: ##STR12## wherein: R.sub.1 and R.sub.6 may be the same or different and are alkyl having from 1 to 12 carbon atoms or hydrocarbyl aralkyl having up to 12 carbon atoms;R.sub.2 -R.sub.5 may be the same or different and are H, R.sub.1 or R.sub.6 ;m is an integer from 3 to 6, inclusive;n is an integer from 3 to 6, inclusive; or(II) a salt thereof with a pharmaceutically acceptable acid; but excluding those polyamines and salts wherein R.sub.1 and R.sub.6 are lower alkyl of 1-4 carbon atoms; R.sub.2 R.sub.5 are H, and m-n-3; comprising administering thereto an anti-neoplastic effective amount of said polyamine or salt thereof.