Patent ID: 8101753
Filing Date: 2012-01-24
Classification: C07D

Abstract:
1. A method for producing a 4-amino-6-alkynyloxypyrimidine compound shown by the formula (V): wherein R which comprises the first step which produces a 4-fluoro-6-alkynyloxypyrimidine compound shown by the formula (I): wherein R by making a 4,6-difluoropyrimidine compound shown by the formula (II): wherein R react with an alcohol compound shown by the formula (III): wherein R in the presence of a tertiary amine; and the second step which produces the 4-amino-6-alkynyloxypyrimidine compound shown by the formula (V) by making the 4-fluoro-6-alkynyloxypyrimidine compound shown by the formula (I) react with an amine compound shown by the formula (IV): wherein R