Patent ID: 6387614
Filing Date: 2002-05-14
Classification: C12Q,G01N,Y10S

Abstract:
A method for measuring biomolecular recognition of at least one toxin by electrochemistry, comprising:a) providing: i) an electrode, ii) an insulator, and iii) liposomes having oxidation/reduction receptors, wherein said liposomes comprise a glycine-terminated diacetylene lipid, an acetylferrocenic diacetylene lipid comprising ferrocene, and a glycosphingolipid, and wherein said glycosphingolipid is known to be a receptor for at least one toxin; b) adding a sample suspected of containing at least one toxin to said liposomes; and c) measuring the current through said ferrocene to determine the biomolecular recognition of said at least one toxin by said liposomes, wherein a drop in said current is indicative of specific biomolecular recognition.