Patent ID: 8987486
Filing Date: 2015-03-24
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A trans-2-decenoic acid derivative represented by the following formula (1′) or a pharmaceutically acceptable salt thereof; wherein Y′ is —O—, —NR′— or —S—; W′ is W1′ when Y′ is —O—, W2′ when Y′ is —NR′— or W3′ when Y′ is —S—; R′ is dialkylaminoalkyl group, alkyl group, or hydrogen atom: (1) W1′ is dialkylaminoalkyl group, alkylthioalkyl group, alkoxyalkyl group, dialkoxyalkyl group or dialkylaminoalkoxyalkyl group; (2-1) W2′ is hydrogen atom, alkyl group or dialkylaminoalkyl group when R′ is dialkylaminoalkyl group; (2-2) W2′ is alkyl group which is same as or different from R′ when R′ is alkyl group (except the case where both R′ and W2′ are ethyl group or methyl group); or (2-3) W2′ is alkyl group (except 2-methylpropyl group and 2-methylbutyl group), cyclohexyl group or pyrrolidinealkyl group when R′ is hydrogen atom; and (3) W3′ is alkyl group, cycloalkyl group, phenylalkyl group or dialkylaminoalkyl group.