Patent ID: 6235479
Filing Date: 2001-05-22
Classification: G01N,G05B

Abstract:
An integrated instrument for automated nucleic acid analysis comprising:a) a sample processing station for providing one or more target nucleic acid sequences from a test sample;b) a first test reaction station for performing a first hybridization reaction on one or more of said target nucleic acid sequences or their complementary sequences, said first reaction comprising a first detection format device having at least one to fifty discrete nucleic acid sequences;c) a second reaction station for performing a second hybridization reaction on one or more of said target nucleic acid sequences or their complementary sequences; said second reaction comprising a second detection format device having greater than one hundred discrete nucleic acid sequences;d) at least one detector for determining positive hybridization detection signals for said target nucleic acid sequences or their complementary sequence in said first and second hybridization reactions; ande) a control module for integrated operation of said instrument wherein said module determines the need for performance of the second hybridization reaction based on the results from said detector and for analysis of detection signals from said first and second hybridization reactions.