Patent ID: 6277892
Filing Date: 2001-08-21
Classification: A61K,A61Q

Abstract:
A topical pharmaceutical composition having enhanced penetration through the skin comprising:a) a safe and effective amount of a pharmaceutical active; andb) from about 0.1% to about 10.0% of a high molecular weight crosslinked cationic polymer of the formula: (A).sub.1 (B).sub.m (C).sub.n where (A) is a dialkylaminoalkyl acrylate monomer or its quaternary ammonium or acid addition salt, (B) is a dialkylaminoalkyl methacrylate monomer or its quaternary ammonium or acid addition salt, (C) is acrylamide, 1 is an integer of 0 or greater, m is an integer of 1 or 0 greater, and n is an integer of 0 or greater, wherein said polymer contains a crosslinking agent, wherein the pharmaceutical active is a sunless tanning agent, wherein said sunless tanning agent is selected from the group consisting of dihydroxyactone, indole derivatives and mixtures thereof.