Patent ID: 6790619
Filing Date: 2004-09-14
Classification: C12N

Abstract:
A method of identifying a herbicide comprising:(a) contacting a host cell said host cell including a polypeptide, said polypeptide having the biological activity of a phosphomevelonate kinase and comprising an amino acid sequence having at least 80% identity with the sequence according to SEQ ID NO:2, with a chemical compound or mixture of chemical compounds under conditions which permit the interaction of the chemical compound or the mixture of chemical compounds with the polypeptide, (b) comparing the biological activity of the polypeptide in the presence of the chemical compound or the mixture of chemical compounds with the biological activity of the polypeptide in the absence of the chemical compound or the mixture of chemical compounds, and (C) determining the chemical compound which specifically modulates the biological activity of the polypeptide thereby identifying the herbicide.