Patent ID: 6518013
Filing Date: 2003-02-11
Classification: A61K,A61P,C07K,C12N

Abstract:
A method for inhibiting transmission of an Epstein-Barr virus to a cell, comprising contacting said cell with an effective concentration of a peptide consisting of a region of 16 to 39 consecutive amino acids of an Epstein-Barr virus protein for an effective period of time, wherein:(a) said region is recognized by one or more of ALLMOTI5, 107Ã—178Ã—4 or PLZIP sequence search motifs; (b) said peptide further comprises an amino terminal X, and a carboxy terminal Z in which: X comprises an amino group, an acetyl group, a 9-fluorenylmethoxy-carbonyl group, a hydrophobic group, or a macromolecular carrier group; and Z comprises a carboxyl group. an amido group, a hydrophobic group, or a macromolecular carrier group; and (c) fusion of said virus to said cell is inhibited.