Patent ID: 8367314
Filing Date: 2013-02-05
Classification: B01J,B82Y,C12Q,C40B,G01N

Abstract:
1. A method of making a biomolecular detector, said method comprising: (a) providing a substrate having a surface portion; (b) depositing a linking layer on said surface portion; and (c) forming a polymer layer on said linking layer by the process of surface-initiated polymerization of monomeric units thereon, with each of said monomeric units comprising a monomer core group having at least one protein-resistant head group coupled thereto, to thereby form a brush molecule on said surface portion; said brush molecule comprising a stem formed from the polymerization of said monomer core groups, and a plurality of branches formed from said head group projecting from said stem; and then (d) covalently coupling a member of a specific binding pair to said polymer layer.