Patent ID: 8513221
Filing Date: 2013-08-20
Classification: A61P,C07D

Abstract:
1. The compound of formula IIc: wherein X is N or CR′; R, R′ are independently hydrogen, alkyl, cycloalkyl, or heterocyclo, each optionally substituted with Z 1 , Z 2 and Z 3 ; Z (1) hydrogen or Z (2) —OH or —OZ (3) —SH or —SZ (4) —C(O) (5) —SO (6) halo; (7) cyano; (8) nitro; (9) —Z (10) —Z (11) oxo; (12) —O—C(O)—Z (13) any two of Z Z (1) a single bond; (2) —Z (3) —Z (4) —Z (5) —Z (6) —Z (7) —Z Z (1) a single bond; (2) alkylene; (3) alkenylene; or (4) alkynylene; each Z (1) hydrogen; (2) —OH or —OZ (3) —SH or —SZ (4) —C(O) (5) —SO (6) halo; (7) cyano; (8) nitro; (9) —Z (10) —Z (11) oxo; or (12) —O—C(O)—Z each Z each Z each Z each Z each Z each Z (1) hydrogen; (2) —OH or —OZ (3) —SH or —SZ (4) —C(O) (5) —SO (6) halo; (7) cyano; (8) nitro; (9) —Z (10) —Z (11) oxo; or (12) —O—C(O)—Z where Z where Z where any two of Z