Patent ID: 7220434
Filing Date: 2007-05-22
Classification: A61K,A61P

Abstract:
1. A pharmaceutical composition comprising one or more orally deliverable dose units, each comprising a first fraction of celecoxib in an amount of about 10 mg to about 400 mg, said first fraction being in solution in a pharmaceutically acceptable solvent and/or present in immediate-release solid particles having a D 90 particle size less than about 1 μm; and a second fraction of the celecoxib in an amount of about 10 mg to about 400 mg, said second fraction being present in solid particles having a D 90 particle size greater than about 25 μm and/or in controlled-release, slow-release, programmed-release, timed-release, pulse-release, sustained-release or extended-release particles; wherein said first fraction and said second fraction of the celecoxib are present in a weight ratio of about 10:1 to about 1:10.