Patent ID: 7943623
Filing Date: 2011-05-17
Classification: A61K,A61P

Abstract:
1. A pharmaceutical composition comprising: (I) at least one oxazole compound selected from the group consisting of 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compounds represented by general formula (1), optically active isomers thereof, and pharmacologically acceptable salts thereof: general formula (1): wherein R 1 represents a hydrogen atom or C 1-6 alkyl group; n represents an integer from 0 to 6; and R 2 represents any of the groups of general formula (A) to (F) below: groups represented by general formula (A): wherein R 3 represents any of the groups (1) to (6) shown below: (1) phenoxy groups, optionally substituted on the phenyl ring with one or more members selected from the group consisting of halogen atoms, halo-substituted or unsubstituted C (2) phenyl C (3) —NR (4) phenyl C (5) phenoxy C (6) benzofuryl C groups represented by general formula (B): wherein R 6 represents a phenyl group, optionally substituted on the phenyl ring with one or more members selected from the group consisting of halogen atoms, halo-substituted or unsubstituted C 1-6 alkyl groups, and halo-substituted or unsubstituted C 1-6 alkoxy groups; groups represented by general formula (C): wherein R 7 represents a phenyl C 2-10 alkenyl group, optionally substituted on the phenyl ring with one or more members selected from the group consisting of halogen atoms, halo-substituted or unsubstituted C 1-6 alkyl groups, and halo-substituted or unsubstituted C 1-6 alkoxy groups, or represents a biphenyl C 1-6 alkyl group, optionally substituted on one or both phenyl rings with one or more members selected from the group consisting of halogen atoms, halo-substituted or unsubstituted C 1-6 alkyl groups, and halo-substituted or unsubstituted C 1-6 alkoxy groups; groups represented by general formula (D): wherein R 8 represents a phenyl C 1-6 alkyl group, optionally substituted on the phenyl ring with one or more members selected from the group consisting of halogen atoms, halo-substituted or unsubstituted C 1-6 alkyl groups, and halo-substituted or unsubstituted C 1-6 alkoxy groups; groups represented by general formula (E): wherein R 8 is the same as above; and groups represented by general formula (F): wherein R 8 is the same as above; and (II) at least one cellulose compound selected from the group consisting of hydroxypropyl methylcellulose phthalate and hydroxypropyl methylcellulose acetate succinate.