Patent ID: 8652504
Filing Date: 2014-02-18
Classification: A61K,A61L,C08G,C08L

Abstract:
1. A method for making a solid polymer composition for controlled release of a bioactive agent comprising: a) casting or spraying onto a removable solid substrate the following polymer layers: b) drying each layer before casting or spraying the next layer thereon, wherein the biodegradable, biocompatible polymer of a) i) comprises at least one or a blend of poly(ester-amide)s (PEAs) having formula (I) or formula (IV); and c) removing the removable solid substrate from the composition prior to use, wherein the PEA of formula (I) is: wherein n ranges from about 5 to about 100; R (C R the R R and combinations thereof; and wherein the PEA of formula (IV) is: wherein n ranges from about 5 to about 150, m ranges about 0.1 to 0.9: p ranges from about 0.9 to 0.1; R R each R the R R R