Patent ID: 8169615
Filing Date: 2012-05-01
Classification: B01L,B82Y,G01N

Abstract:
1. A method for providing a functionalized micro-sensor for detecting the presence of two or more different target analytes, ligands or molecules in a test fluid, comprising: providing surface plasmon resonant (SPR) elements in two or more bands corresponding to each of the targets, mounted on a common light transmissive substrate, where the SPR elements include a light transmissive bead formed in a geometric shape that can sustain periodic boundary conditions for a stationary plasmon resonance wave to travel across the outer surface thereof, and a pinhole is defined at the interface between said SPR element and the light transmissive substrate; defining a fluid flow channel corresponding to each of the two or more bands of SPR elements; flowing a functionalizing chemical through each fluid flow channel capable of functionalizing the SPR elements in the corresponding band to bind with the corresponding target.