Patent ID: 6706700
Filing Date: 2004-03-16
Classification: A61P,C07J

Abstract:
A compound satisfying the structural formula whereinR1 is O, (H,H), (H,OR), NOR, with R being hydrogen, (C1-6) alkyl, (C1-6) acyl; R2 is hydrogen, or (C1-6) alkyl; R3 is hydrogen; or R3 is (C1-6) alkyl (C2-6) alkenyl, or (C2-6) alkynyl, each optionally substituted by halogen; R4 is hydrogen, (C1-6) alkyl, or (C2-6) alkenyl; R5 is (C1-6) alkyl; R6 is hydrogen, halogen, or (C1-4) alkyl; R7 is hydrogen, or (C1-6) alkyl; R8 is hydrogen, hydroxy, (C1-6) alkoxy, halogen, or (C1-6) alkyl; R9 and R10 are independently hydrogen; or R9 and R10 are independently (C1-6) alkyl, (C2-6) alkenyl, (C3-6) cycloalkyl, (C5-6) cycloalkenyl, or (C2-6) alkynyl, each optionally substituted by (C1-4) alkoxy, or halogen; R11 is hydrogen, SO3H, (C1-15) acyl; and the dotted lines indicate optional bonds, selected from a &Dgr;4, &Dgr;5(10), or &Dgr;11 double bond, or a &Dgr;4,9 or &Dgr;4,11 diene system.