Patent ID: 8455479
Filing Date: 2013-06-04
Classification: A61P,C07D

Abstract:
1. A compound of Formula I, or a pharmaceutically acceptable salt or a stereoisomer thereof, wherein: Ar represents phenyl; which may further be unsubstituted or may be optionally substituted at any available position by one or more substituents selected from halogen, CN, hydroxyl, NH R R R R R R R R m represents 1 or 2; n represents 1, 2, 3 or 4; r represents 1, 2, 3 or 4; wherein said heterocyclyl is chosen from oxazolidinyl, tetrahydrofuranyl, dihydrofuranyl, dihydropyridinyl, dihydroisooxazolyl, dihydrobenzofuryl, azabicyclohexyl, dihydroindonyl, piperidinyl, piperazinyl, morpholinyl, thiomorpholinyl, benzomorpholinyl, fluoropyrrolidinyl, difluoropyrrolidinyl, piperidinyl, fluoropiperidinyl, difluoropiperidinyl, piperidinonyl, hydroxy pyrrolidinyl, tetrahydroisoquinolinyl, dimethoxytetrahydroisoquinolinyl, and pyrrolidinyl; and wherein said heteroaryl is chosen from oxazolyl, imidazolyl, pyrrolyl, 1,2,3,-triazolyl, 1,2,4-triazolyl, tetrazolyl, thiazolyl, oxadiazolyl, benzoimidazolyl, thiadiazolyl, pyridinyl, pyridazinyl, pyrimidinyl, thienyl, isoxazolyl, triazinyl, furanyl, benzofuranyl, indolyl, benzothiazolyl, and benzoxazolyl.