Patent ID: 8980614
Filing Date: 2015-03-17
Classification: C12N,C12Y

Abstract:
1. An isolated or recombinant cDNA encoding an antimicrobial φSH2 endolysin-derived peptidoglycan hydrolase molecule having specificity and exolytic activity for the peptidoglycan cell wall of untreated Staphylococcus aureus and coagulase negative staphylococci (CNS), said CNS comprising S. chronogenes, S. epidermis, S. hyicus, S. simulans, S. wameri , and S. xylocus wherein said cDNA encodes a truncated endolysin-derived peptidoglycan hydrolase molecule having the sequence of SEQ ID NO:4, SEQ ID NO:16 or SEQ ID NO:24.