Patent ID: 7337073
Filing Date: 2008-02-26
Classification: G16B,G16C

Abstract:
1. An activity evaluation method for a drug candidate agent comprising: setting as k analysis points one or more atoms among atoms constituting a drug candidate agent, wherein the drug candidate agent is a forskolin derivative; calculating an activity of said drug candidate agent with respect to a protein, wherein the protein is an adenylate cyclase, based on a predetermined evaluation expression having Fukui function values as variables obtained by numerical calculation for the analysis points; and comparing said activity obtained from the calculation with the same activity of said drug candidate agent with respect to said protein obtained from an experiment, wherein a first Fukui function value f wherein an activity P of said drug candidate agent with respect to said protein is calculated based on the following evaluation expression (5) composed of a first coefficient D (where n is the total number of analysis points k); and wherein the results of the calculations are outputted to a user.