Patent ID: 6143908
Filing Date: 2000-11-07
Classification: C07D

Abstract:
A process for preparing a 1,3-dioxolane-4-methanol compound of the formula ##STR7## wherein R.sup.1 and R.sup.2 are the same or different and are hydrogen atom, alkyl having 1 to 4 carbon atoms or phenyl, and R.sup.1 and R.sup.2 may form a cycloalkyl ring having 3 to 6 carbon atoms with the adjacent carbon atoms,which is characterized in acetalizing a 3-halogeno-1,2-propanediol of the formula ##STR8## wherein X is a halogen atom, with an acetalizing agent in the presence of an acid catalyst to prepare a 4-halogenomethyl-1,3-dioxolane of the formula ##STR9## wherein R.sup.1, R.sup.2 and X are as defined above, and reacting it with an alkali metal salt or alkaline earth metal salt of an alcohol of the formula (3)ROH (3)wherein R is aralkyl or allyl,to prepare a compound of the formula ##STR10## wherein R, R.sup.1 and R.sup.2 are as defined above, and subjecting it to hydrogenolysis in the presence of a reductive catalyst.