Patent ID: 7173025
Filing Date: 2007-02-06
Classification: A61P,C07D

Abstract:
1. An aminoheterocyclic compound of the formula I wherein G G m is 1 or 2; R L T R provided that, when T X Ar is a 1,3-phenylene or 1,4-phenylene, wherein said phenylene ring is optionally substituted with 1 or 2 substituents selected X Q is phenyl, naphthyl, phenyl-(1-4C)alkyl, phenyl-(2-4C)alkenyl or phenyl-(2-4C)alkynyl, and Q optionally bears 1, 2 or 3 substituents selected from halogeno, trifluoromethyl, trifluoromethoxy, cyano, hydroxy, amino, nitro, trifluoromethanesulphonyl, carboxy, carbamoyl, (1-4C)alkyl, (2-4C)alkenyl, (2-4C)alkynyl, (1-4C)alkoxy, (2-4C)alkenyloxy, (2-4C)alkynyloxy, (1-4C)alkylthio, (1-4C)alkylsulphinyl, (1-4C)alkylsulphonyl, (1-4C)alkylamino, di-(1-4C)alkylamino, (1-4C)alkoxycarbonyl, or a pharmaceutically-acceptable salt thereof; provided that when X 1 is CO and Ar is phenylene which optionally bears 1 or 2 substituents selected from halogeno, trifluoromethyl, (1-4C)alkyl and (1-4C)alkoxy then X 2 is not N(R 7 )SO 2, N(R 7 )CO, C(R 6 ) 2 S, C(R 6 ) 2 SO, C(R 6 ) 2 SO 2 , C(R 6 ) 2 —C(R 6 ) 2 , C(R 6 ) 2 CO or C(R 6 ) 2 O.