Patent ID: 7169750
Filing Date: 2007-01-30
Classification: A61K,A61P

Abstract:
1. A method to obtain progenitor and/or stem cells, from a subject, which method comprises (a) administering to said subject a compound of the formula or pharmaceutically acceptable salt or prodrug form thereof wherein Z is of the formula wherein A comprises a monocyclic or bicyclic fused ring system containing at least one N and B is H or an organic moiety of 1–20 atoms, Z′ is of the formula wherein Ar is an aromatic or heteroaromatic moiety, and each Y is independently a non-interfering substituent and j is 0–3; and “linker” represents a bond, alkylene (1–6C) or may comprise aryl, fused aryl, oxygen atoms contained in an alkylene chain, or may contain keto groups or nitrogen or sulfur atoms; in an amount effective to mobilize said progenitor and/or stem cell population in said subject; followed by (b) harvesting said progenitor and/or stem cells.