Patent ID: 6989451
Filing Date: 2006-01-24
Classification: C07D

Abstract:
1. A compound selected from the group consisting of the following, or a salt thereof: 5-(3-methylphenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(4-methoxyphenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(2-methoxyphenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(3-methoxyphenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(2-chlorophenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(4-nitrophenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(1-naphthyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(4-phenyl-2-methoxyphenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(2,6-di-isopropylphenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(2-dimethylamino-1-naphthyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(4-dimethylamino-1-naphthyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(2-trichloromethyl-phenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(4-aminophenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(4-acetyl-phenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(4-methoxycarbonyl-phenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(2-fluorophenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(2-methoxycarbonyl-phenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(2,4-dichlorophenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(1-indanyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(pyridin-3-yl)amino-3-hydroxy-4-cyano-isothiazole; 5-(4-chlorophenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(3-chlorophenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(3-trichloromethyl-4-chlorophenyl)amino-3-hydroxy-4-cyano-isothiazole; 5-(3,5-dichlorophenyl)amino-3-hydroxy-4-cyano-isothiazole; and 5-(4-bromophenyl)amino-3-hydroxy-4-cyano-isothiazole.