Patent ID: 9161964
Filing Date: 2015-10-20
Classification: A61K,A61P

Abstract:
1. A method for treating invasion and metastasis of a cancer mediated by EGFR receptor, comprising administering an effective amount of an immunomodulatory protein (GMI) from Ganoderma microsporum , or a recombinant thereof, to a subject in need of such treatment, wherein the GMI has the amino acid sequences of: (1)-Leu-Ala-Trp-Asn-Val-Lys-(LAWNVK; SEQ ID NO:1) and (2)-Asp-Leu-Gly-Val-Arg-Pro-Ser-Tyr-Ala-Val-(DLGVRPSYAV; SEQ ID NO:2) or the amino acid sequence of: