Patent ID: 7312188
Filing Date: 2007-12-25
Classification: A61K,A61P,C07K

Abstract:
1. A compound represented by the general formula (1): wherein A is amino group, or amino group protected with a protecting group which can be degraded in a living body, B in which R D is a single bond, —NHCO— or NHCO—R in which R E is —COOH, a group equivalent to COOH, hydrogen atom, hydroxy group, amino group, halogen atom, or —COOCH n is an integer of 1 to 3, m is an integer of 1 to 3, G is hydroxy group, amino acid residue, a peptide constructed of 2 to 4 amino acids, or a group represented by the formula in which Z is —NH—, -Asp-Ala-NH—, -Asp-Ala-, —NH-CZ Ring L is a 5- to 10-membered ring optionally containing a heteroatom and/or unsaturated bond, Z X is hydrogen atom, —COOH, a group equivalent to COOH, —CONHR in which X′ is hydrogen atom, —COOH, a group equivalent to COOH, —CONHR Y and Y′ are each hydrogen atom, —COOH, a group equivalent to COOH, —CONHR k is an integer of 1 to 4, and R or a pharmaceutically acceptable salt thereof, or a prodrug thereof.