Patent ID: 6440413
Filing Date: 2002-08-27
Classification: A61K,A61P

Abstract:
A method of treatment of hyperviscosity of the intestinal, bronchial and/or genital mucus in warm-blooded animals which comprises administering to warm-blood animals suffering from intestinal, bronchial and/or genital hyperviscosity of the mucus, a safe but effective amount of the proteinase composition comprising as the active ingredient the preponderant exocellular proteinase produced by a culture of Streptomyces fradiae, which is defined as having a specific activity of greater than 100,000 A.U./mg, a molecular weight around 19 kDa and an isoelectric point around 8.5 and which is capable of selectively destroying sub-unit A of cholera toxin, without destroying sub-unit B of cholera toxin, admixed or combined with an inert-non-toxic physiologically acceptable diluent or vehicle.