Patent ID: 8013006
Filing Date: 2011-09-06
Classification: A61K,A61P,Y02A

Abstract:
1. A compound of Formula (I): wherein: X is: -cyano; Y is: -aryl substituted with one or more of the following: Z is: -hydrogen; —C —C -aryl optionally substituted with C —COOR -cyclopropyl; -cyclobutyl; -cyclopentyl; -cyclohexyl; -cyclopropylmethyl; -cyclobutylmethyl; or -cyclopentylmethyl; R is hydrogen, halogen or C R -hydrogen; -hydroxy; -halogen; —C -nitro; -5 or 6 membered heteroaryl; -5 or 6 membered heterocycle; —C -aryl optionally substituted with C —COR —C -cyclopropyl; -cyclobutyl; -cyclopentyl; or -cyclohexyl; and wherein when R R -nitro; -hydrogen; -halogen; -hydroxy; —C -cyclopropyl; -cyclobutyl; -cyclopentyl; -cyclohexyl; -amino; —C —COOR —C -amide optionally substituted with: -5 or 6 membered heteroaryl; —OCOR —NHCOR —OR —NHSO —NHSO —NHSO —NHSO —NHSO and wherein when R R -hydrogen; or —CH or a pharmaceutically acceptable salt thereof.