Patent ID: 6369094
Filing Date: 2002-04-09
Classification: A61P,C07D

Abstract:
A crystalline, polymorphic form of a compound of formula (I) characterized by any of:(i) a powder X-ray diffraction pattern obtained using copper K-alpha1 radiation (&lgr;=0.15046 nm) which shows main peaks at 9.28, 10.38, 11.37, 12.40, 16.84, 17.46, 17.53, 17.78, 17.98, 19.48, 20.70, 21.29, 21.45, 22.21, 22.64, 23.08, 25.20 and 25.79; (ii) an infrared spectrum as a KBr disc which shows significant absorption bands at &ngr;=3385.3, 3172.0, 3143.8, 3058.0, 3022.6, 2954.8, 2928.3, 2893.5, 2650.7, 2436.4, 1622.6, 1584.1, 1480.8, 1445.6, 1362.4, 1354.4, 1304.8, 1246.0, 1229.9, 1164.3, 1149.6, 1137.5, 1087.1, 1071.7, 1019.5, 958.9, 929.8, 899.1, 878.9, 842.6, 793.8, 759.3, 751.4, 731.3, 690.4, 619.9, 606.3, 564.9, 533.7, 512.2, 503.6, 485.3, 457.5 and 428.9 cmâˆ’1; or (iii) a DSC trace which shows a sharp endotherm at 226Â° C.