Patent ID: 7319012
Filing Date: 2008-01-15
Classification: A61P,C07K,C12N,C40B,G01N

Abstract:
1. A method of screening a library of target organism polypeptides in order to identify a target organism antigen that is capable of eliciting a humoral immune response, comprising: (a) providing a library of target organism polypeptides attached to a linker molecule, wherein the library is generated according to a method comprising the steps of: (b) immobilizing at least 10 of the target organism polypeptides attached to a linker molecule from the library to a solid support, wherein the linker molecule immobilizes the target organism polypeptide to the solid support; and (c) assaying the target organism polypeptides immobilized to the solid support with at least one antibody from an animal that has been immunized with one or more antigens from the target organism, thereby screening a library of target organism polypeptides in order to identify a target organism antigen that is capable of eliciting a humoral immune response.