Patent ID: 7279177
Filing Date: 2007-10-09
Classification: A61L,C08L,D04B,D10B,Y10T

Abstract:
1. A process for making a wound dressing for use with moderate to severe bleeding, the wound dressing comprising a fabric substrate that comprises oxidized regenerated cellulose fibers and from about 8 to about to about 20 percent by weight of water-soluble oligosaccharides; and a biocompatible, water-soluble or water-swellable polymer matrix of sodium carboxymethyl cellulose, the process consisting of the steps of: providing a solution having dissolved therein sodium carboxymethyl cellulose, providing a fabric substrate having a first surface and a second surface opposing said first surface, said fabric substrate having flexibility, strength and porosity effective for use as a hemostat, said fabric substrate comprising a carboxylic-oxidized cellulose fibers and from about 8 to about 20 percent by weight of water-soluble oligosaccharides, contacting said solution with said fabric substrate under conditions effective to substantially homogeneously distribute said solution on said first and second surfaces and through said fabric substrate, lyophilizing said fabric substrate with said solution distributed there through, thereby forming a porous, polymeric matrix having a microporous structure.