Patent ID: 8354399
Filing Date: 2013-01-15
Classification: A61P,C07D

Abstract:
1. A compound of formula (I) Ar is aryl or heteroaryl substituted with Ra and Rb, wherein Ra is NO Rb is hydrogen, halogen, NO Hal is halogen, A is optionally substituted heterocyclyl, E is straight or branched unsubstituted C G is straight or branched substituted C G′ is straight or branched C L is optionally substituted heteroaryl; Ar′ is an optionally substituted aryl or heteroaryl; R1, R2 and R3 are independently hydrogen, halogen, nitro, an optionally substituted straight or branched C NR4R5 or OR6, wherein R4 and R5 are independently hydrogen, alkenyl, alkynyl, R8R9N—C R6 is hydrogen, alkenyl, alkynyl, COR7, SOR10, SO R7 is hydrogen, alkenyl, alkynyl, NR4R5, OR6, SR6, R8R9N—C R8 and R9 are independently hydrogen, alkenyl, alkynyl, COR7, an optionally further substituted straight or branched C R10 is hydrogen, alkenyl, alkynyl, NR4R5, OR6, R8R9N—C R′ and R″ are each independently hydrogen or an optionally substituted straight or branched C n is 0 or 1, and pharmaceutically acceptable salt thereof.