Patent ID: 6476272
Filing Date: 2002-11-05
Classification: C07F

Abstract:
A method for the production of a primary, secondary or tertiary phosphine having the formula (R)aP(H)3âˆ’a where R is an organic group and a is 1, 2 or 3, wherein said method comprises the following stages:(i) reacting a tris(hydroxyorgano)phosphine (THP) with an organic halogen-containing compound, of formula R(X)n where: R is selected from the group consisting of C1 to C20 alkyl, alkenyl, alkynyl, alkaryl and styryl; X represents a halogen atom; n is a whole number of from 1 to 4 and said R includes at least one aliphatic carbon atom adjacent each said halogen atom; â€ƒsaid stage (i) being carried out at a temperature of less than about 90Â° C. and at ambient pressure and in the presence of a solvent; (ii) reacting the product of stage (i) with a base; (iii) thereafter adding, to the resulting product of stage (ii), sufficient of an acid to maintain a pH of 6 to 8, removing aldehydes from said product of stage (ii) and adding to said product a material to form a discrete organic phase, followed by distilling or phase-separation to obtain said primary, secondary or tertiary phosphine.