Patent ID: 6399582
Filing Date: 2002-06-04
Classification: A61P,C07H

Abstract:
A compound of the formula I: wherein:X is H, F, Cl, Br, or I; R2 is selected from the group consisting of H,â€”COCH3 and â€”COPhenyl; R6 is selected from the group consisting of H and (C1-C6) alkoxy; R13 is selected from the group consisting of H, (C1-C8) alkyl, 1-alkenyl (C2-C8), 1-alkynyl (C2-C8), substituted (C1-C8)alkyl, and â€”CH2â€”Râ€³ where Râ€³ is selected from the group consisting of H, (C1-C8) alkyl, substituted (C1-C8)alkyl, cycloalkyl, alkenyl (C2-C8), alkynyl (C2-C8), aryl, substituted-aryl, (C1-C8) alkylaryl, heterocyclo, and substituted heterocyclo; provided that R13 can not be ethyl or 1-hydroxy ethyl; R is selected from the group consisting of H, aryl, substituted-aryl, heterocyclo, substituted-heterocyclo, cycloalkyl, C1-C8-alkyl and C2-C8-alkenyl optionally substituted with one or more substituents selected from the group consisting of aryl, substituted-aryl, heterocyclo, substituted-heterocyclo, hydroxy, C1-C6-alkoxy; or a pharmaceutically acceptable salt, ester or a pro-drug form thereof.