Patent ID: 6054566
Filing Date: 2000-04-25
Classification: C07K,C12N,C12P,C12Y

Abstract:
A recombinant animal viral nucleic acid constructed from a nonretroviral (+) sense, single stranded RNA animal virus possessing a naturally occurring subgenomic promoter, the recombinant animal viral nucleic acid comprising:a first viral subgenomic promoter;a nucleic acid sequence that codes for a viral coat protein whose transcription is regulated by the first animal viral subgenomic promoter;a second animal viral subgenomic promoter;a second nucleic acid sequence whose transcription is regulated by the second animal viral subgenomic promoter; anda third viral subgenomic promoter and a third nucleic acid sequence;wherein the first, second, and third viral subgenomic promoters possess heterologous nucleic acid sequences relative to each other.