Patent ID: 6670479
Filing Date: 2003-12-30
Classification: C07C,C07D

Abstract:
A free radical intermediate of the formula wherein said fused aryl and/or heterocyclic ring comprisesa C6-C14 N aryl group; a 5 to 7 membered saturated monocyclic ring comprising carbon atoms and 1 to 4 heteroatoms selected from the group consisting of N, O, and S; a 5 to 7 membered partially saturated monocyclic ring comprising carbon atoms and 1 to 4 heteroatoms selected from the group consisting of N, O, and S; a 5 to 7 membered aromatic ring comprising carbon atoms and 1 to 4 heteroatoms selected from the group consisting of N, O, and S; a 7 to 10 membered saturated bicyclic heterocyclic ring comprising carbon atoms and 1 to 4 heteroatoms selected from the group consisting of N, O, and S; a 7 to 10 membered partially saturated bicyclic heterocyclic ring comprising carbon atoms and 1 to 4 heteroatoms selected from the group consisting of N, O, and S; or a 7 to 10 membered aromatic bicyclic heterocyclic ring comprising carbon atoms and 1 to 4 heteroatoms selected from the group consisting of N, O, and S; and said fused aryl and/or heterocyclic ring possesses an sp2 hybridized carbon radical alpha to its point of attachment, and wherein each of the groups R4, R5, and R8 are independently selected from hydrogen, aryl; heteroaryl; hydrocarbyl; substituted aryl; substituted heteroaryl; substituted hydrocarbyl; heteratom connected aryl; heteroatom connected hydrocarbyl; heteroatom connected substituted hydrocarbyl; heteroatom connected heteroaryl; heteroatom connected substituted aryl; halo; amino; cyano; hydroxy; carboxy; a group of the formula â€”C(O)Oâ€”C1-C8 alkyl; a group of the formula â€”C(O)R1; a group of the formula â€”Oâ€”R1; a group of the formula â€”NHR1; a group of the formula â€”N(R1)2; C1-C8 alkoxy; C1-C8 alkylthio; or two of R5 and R6, or two R8 groups taken together can form a divalent hydrocarbyl, substituted hydrocarbyl, or be bonded directly to a heteroatom selected from oxygen, nitrogen, or sulfur; and n is a number equivalent to available sites on said aryl and/or heterocyclic ring;in addition, two R4 groups and/or two R5 groups can be taken together represent oxo;R1 is selected from the group consisting of aryl, heteroaryl, hydrocarbyl, substituted aryl, substituted heteroaryl, and substituted hydrocarbyl; provided that R1 is bonded via a carbon atom; andR6 and R7 are independently selected from aryl, heteroaryl, hydrocarbyl, substituted aryl, substituted heteroaryl, and substituted hydrocarbyl; provided that said groups are bonded via a carbon atom.