Patent ID: 6294694
Filing Date: 2001-09-25
Classification: A61P,C07C,C40B

Abstract:
A compound having a structure as shown in Formula I or Formula II: ##STR29##wherein R.sup.1 is selected from the group consisting of H, C.sub.1-12 -alkyl, C.sub.3-8 -cycloalkyl, C.sub.3-8 -cycloalkyl-C.sub.1-12 -alkyl, amino-C.sub.1-12 -alkyl, N--C.sub.1-6 -alkylamino-C.sub.1-12 -alkyl, N,N-di-C.sub.1-6 -alkylamino-C.sub.1-12 -alkyl, ##STR30##and ##STR31##wherein R.sup.5 and R.sup.6 are independently selected from the group consisting of H, C.sub.1-6 -alkyl, C.sub.1-6 -alkylthio, C.sub.1-6 -alkoxy, fluoro, chloro, bromo, iodo, and nitro; and X is halo;wherein R.sup.4 is selected from the group recited above for R.sup.1, and R.sup.7 is selected from the group consisting of ##STR32##R.sup.2 and R.sup.3 are selected from the group consisting of ##STR33##wherein R.sup.5 and R.sup.6 are as described above; and pharmaceutically-suitable salts thereof.