Patent ID: 6503909
Filing Date: 2003-01-07
Classification: A61P,C07D

Abstract:
A method of treating a human or animal subject suffering from, or susceptible to, epilepsy, which method comprises administering to said subject a therapeutically effective amount of a compound of formula (I) whereinR1 is phenyl substituted by one or more halogen atoms; R2 is â€”NH2; R3 is â€”NH2 or hydrogen; R4 is â€”CXN Ra Rb, â€”CXNHâ€”(CH2)yN Ra Rb; â€ƒwherein X is &boxH;O or &boxH;S; y is an integer zero, 1 or 2; Ra and Rb, which may be the same or different, are selected from the group consisting of hydrogen and C1-4 alkyl, or together with the nitrogen atom to which they are attached, form a saturated 5- or 6-membered heterocycle containing one or two nitrogen heteroatoms, which heterocycle can be further substituted with one or more C1-4 alkyl groups; or a pharmaceutically acceptable salt or solvate thereof.