Patent ID: 7820143
Filing Date: 2010-10-26
Classification: A61K,A61P,C07D,C09B

Abstract:
1. An article of manufacture, comprising packaging material and a compound contained within the packaging material or salt thereof wherein the compound or salt thereof is effective in a photodynamic therapy treatment for ameliorating the symptoms of a hyperproliferative disorder; and the packaging material includes a label that indicates that the compound or salt thereof is used in a photodynamic therapy treatment for ameliorating the symptoms of a hyperproliferative disorder and the compound is a pharmaceutically acceptable tetrapyrollic photosensitizer compound having at least one pendant —CH 2 CH 2 CON(CH 2 CON(CH 2 COOH) 2 ) 2 or —N(CH 2 COOH) 2 group or esters thereof said tetrapyrollic compound being a chlorin, bacteriochlorin, porphyrin, pyropheophorbide, purpurinimide, or bacteriopurpurinimide wherein the compound has the formula: wherein: R where X is an aryl or heteroaryl group; n is an integer of 0 to 6; R is independently H or lower alkyl of 1 through 8 carbon atoms; where R R R R R R R R R R R each of R each Q is independently unsubstituted or is substituted with one or more substituents each independently selected from Q