Patent ID: 8460670
Filing Date: 2013-06-11
Classification: A61K,A61P,C07K

Abstract:
1. An isolated monoclonal antibody, wherein said monoclonal antibody is specifically binding influenza M2e antigen, and wherein said monoclonal antibody is a human monoclonal antibody, and wherein said antibody comprises at least one antigen binding site, wherein said antigen binding site comprises: (a) one light chain variable region (LCVR), wherein said LCVR comprises: (i) one light chain complementarity determining region (LC CDR) 1, wherein said LC CDR1 consists of the peptide of any one of SEQ ID NOs 1, 2, 3, 4, 5, and 6; (ii) one LC CDR2, wherein said LC CDR2 consists of the peptide of SEQ ID NO:7; and (iii) one LC CDR3, wherein said LC CDR3 consists of the peptide of any one of SEQ ID NOs 8, 9, 10, and 11; and (b) one heavy chain variable region (HCVR), wherein said HCVR comprises: (i) one heavy chain complementarity determining region (HC CDR) 1, wherein said HC CDR1 consists of the peptide of SEQ ID NO:12; (ii) one HC CDR2, wherein said HC CDR2 consists of the peptide of any one of SEQ ID NOs 13 and 14; and (iii) one HC CDR3, wherein said HC CDR3 consists of the peptide of any one of SEQ ID NOs 15, 16, 17, 18, and 19.