Patent ID: 6787653
Filing Date: 2004-09-07
Classification: A61P,C07D

Abstract:
A process for preparing compound represented by formula (1) or a salt thereof: wherein R1, R2 and R3 each, independently, represent a hydrogen atom or a substituent selected from the group consisting of a hydroxyl group, halogen atoms, lower alkyl groups which may be substituted by 1 to 3 halogen atoms, lower alkoxy groups, amino group, mono(lower alkyl)amino groups, di(lower alkyl)amino groups, lower alkylthio groups, lower alkanoyl groups, and a formyl group, which comprises reacting, in the presence of a metal catalyst, a halogenobenzoic acid compound represented by formula (2): wherein X represents a halogen atom, with a compound represented by formula (3): wherein R1, R2 and R3 have the same meanings as defined above, and Y represents a leaving group having an element selected from the group consisting of boron, silicon, zinc, tin, and magnesium.