Patent ID: 7122649
Filing Date: 2006-10-17
Classification: C07H,C07J,C12N,H04J

Abstract:
1. A compound comprising a plurality of linked nucleosides including a plurality of 2′-deoxy′-2′-fluoro, 2′-O—C 1 –C 20 -alkyl, 2′-O—C 2 –C 20 -alkenyl, 2′-O—C 2 –C 20 -alkynyl, 2′-S—C 1 –C 20 -alkyl, 2′-S—C 2 –C 20 -alkenyl, 2′-S—C 2 –C 20 -alkynyl, 2′-NH—C 1 –C 20 -alkyl, 2′-NH—C 2 –C 20 -alkenyl or 2′-NH—C 2 –C 20 -alkynyl nucleosides; and a 5′-O-terminal nucleoside having a conjugate group linked via a linker to the 5′-O-position of the nucleoside, provided that the compound does not include sulfamate or sulfamide internucleotide linkages.