Patent ID: 7521428
Filing Date: 2009-04-21
Classification: A61K,A61P,C07H

Abstract:
1. A purified macrolide derivative, having an enhancing effect for activities of antifungal agents, represented by the formula [I]: wherein when R1 is Ac, R2 and R3 are Ac, and R4 is Me; when R1 is H, R2 and R3 are Ac, and R4 is Me; when R1 is H, R2 and R3 are Ac, and R4 is H; when R1 is Bzl, R2 and R3 are Bzl, and R4 is Me; when R1 is Ac, R2 and R3 are Pr, and R4 is Me; when R1 is Ac, R2 and R3 are Hex, and R4 is Me; when R1 is Ac, R2 and R3 are Bzl, and R4 is Me; when R1 is H, R2 and R3 are Pr, and R4 is Me; when R1 is H, R2 and R3 are Hex, and R4 is Me; when R1 is H, R2 and R3 are Bzl, and R4 is Me; when R1 is H, R2 is H and R3 are Bzl, and R4 is Me; when R1 is H, R2 and R3 are Hex, and R4 is H; or when R1 is H, R2 and R3 are Hex, and R4 is Et.