Patent ID: 6706739
Filing Date: 2004-03-16
Classification: C07D

Abstract:
A compound having the formula: wherein each of R1 and R3 independently is C6-12 aryl, C6-12 aralkyl, or heteroaryl, optionally substituted with halogen, â€”OR4, Cl1-4 alkyl, C1-4 haloalkyl, C1-4 alkyl-OR4, â€”CN, â€”NO2, â€”C(O)R4, â€”SR4, â€”S(O)R4, â€”S(O)2R4, â€”NR4R5, â€”C(O)OR4, â€”C(O)N R4R5, â€”NO2, â€”O(O)CR4, â€”NR4(O)CR5, â€”NR4C(O)OR5, â€”NR4C(O)NR5R6, or R7, provided that if R1 is heteroaryl, the heteroaryl forms a Câ€”N bond with the imidazolidinone ring; in which each of R4, R5, and R6, independently, is H or C1-4 alkyl; and R7 is C6-12 aryl, C6-12 aralkyl, or heteroaryl, optionally substituted with halogen, C1-4 alkyl, C1-4 haloalkyl, â€”OR4, â€”NO2, â€”C(O)OR4, â€”CN, â€”NR4R5, or â€”NR4C(O)OR5; R2 is H, C1-5 alkyl, C1-5 haloalkyl, C6-12 aryl, C6-12 aralkyl, or heteroaryl, optionally substituted with halogen, â€”OR4, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkyl-OR4, â€”CN, â€”C(O)R4, â€”SR4, â€”S(O)R4, â€”S(O)2R4, â€”NR4R5, â€”C(O)OR4, â€”C(O)NR4R5, â€”NO2, â€”O(O)CR4, â€”NR4(O)CR5, â€”NR4C(O)OR5, or â€”NR4C(O)NR5R6; in which R4, R5, R6, and R7 are defined as above; T is NH or O; W is â€”CH2â€”Oâ€”, â€”(CH2)2â€”Oâ€”, â€”(CH2)3â€”Oâ€”, or â€”(CH2)4â€”Oâ€”; m is 4, 5, 6, 7 or 8; and each of x and y independently is 0 or 1, provided that at least one of x and y is 1.