Patent ID: 8283312
Filing Date: 2012-10-09
Classification: A61K,A61P

Abstract:
1. A pharmaceutical composition for reducing body weight or rate of weight gain, comprising an effective amount of a combination of (a) one or more of PYY, a peptide consisting of amino acid 3 to 36 of a human PYY, PYY 3-36 , PYY 22-36 , BIM-43004, BIM-43073D, BIM-43004C, N-α-Ac-[Phe 27 ]PYY(22-36), N-α-Ac-[TRP27]PYY(22-36), N-α-Ac-[Thi 27 ]PYY(22-36), N-α-Ac-[Tyr 22 , Phe 27 ]PYY(22-36), [Im-DNP-His 26 ]PYY, PYY(22-36), [Ala 32 ]PYY(22-36), [Ala 23,32 ]PYY(22-36), [Glu 28 ]PYY(22-36), N-α-Ac-PYY(22-36), N-α-Ac-[p.Cl-Phe 27 ]PYY(22-36), N-α-Ac-[Glu 26 ]PYY(22-36), N-α-Ac-[N-Me-Tyr 36 ]PYY(22-36), N-α-Myristoyl-PYY(22-36), N-α-Naphthaleneacetyl-PYY(22-36), N-α-Ac-[Phe 27 ]PYY(22-36), N-α-Ac-[Bth 27 ]PYY(22-36), N-α-Ac-[Bip 27 ]PYY(22-36), N-α-Ac-[Nal 27 ]PYY(22-36), N-α-Ac-[Tic 27 ]PYY(22-36), N-α-Ac-[Phe 27 ]PYY(25-36), N-α-Ac-[Trp 27 ]PYY(22-36), PYY(13-36), NPY(13-36), and (b) a ghrelin.