Patent ID: 6441212
Filing Date: 2002-08-27
Classification: A61P,C07F

Abstract:
A Human Immunodeficiency Virus (HIV) protease inhibitor of formula II in whichn is 3 to 50; formula II is a stable molecule; each of A and B is independently a) a C3-C10-alkyl, or a substituent obtained by substituting at least one carbon atom of a C3-C10-alkyl group with a heteroatom; b) a C4-C7-aryl, or a substituent obtained by substituting at least one carbon atom of a C4-C7-aryl group with a heteroatom; c) a C3-C10-carbocyclic moiety, or a 3-10-membered heterocyclic group; or moieties of the formulas â€ƒwherein in d), e) and f), CH is bonded to silicon; and wherein R1 to R11 are independently hydrogen, alkyl of 1 to 10 carbons or heteroatoms, aryl of 4 to 14 carbons or heteroatoms, arylalkyl of 5 to 20 carbons or heteroatoms, or a substituted carbonyl; wherein each of said heteroatoms is selected from the group consisting of nitrogen, oxygen, silicon and sulfur, and at least one of A and B, or both of A and B, are selected from a group consisting of d), e) and f).