Patent ID: 6110469
Filing Date: 2000-08-29
Classification: A61P,C07K,C12N

Abstract:
Isolated and purified 38 kDa antigen of wild type (pre-protein) Mycobacterium tuberculosis which is produced by Escherichia coli comprising a hybrid plasmid having a DNA coding 17, 18, 19, 20, 21 or 22 amino acids of the 38 kDa antigen (pre-protein) and having a restriction site within its recognition sequence comprising the base triplet ATG, wherein the 17, 18, 19, 20, 21 or 22 amino acids comprise contiguous 16, 17, 18, 19, 20 or 21 amino acids of the SID NO. 1 and in addition said base triplet ATG starting from the N-Terminus of the produced protein.