Patent ID: 7527786
Filing Date: 2009-05-05
Classification: A01K,A61K,A61P,C07K,G01N

Abstract:
1. A method for inhibiting the growth of a bladder cancer cell expressing a Prostate Stem Cell Antigen (PSCA) protein having the amino acid sequence of SEQ ID NO:2 comprising contacting the bladder cancer cell with a monoclonal antibody designated 1G8 (ATCC No. HB-12612), 2A2 (ATCC No. HB-12613), 2H9 (ATCC No. HB-12614), 3C5 (ATCC No. HB-12616), 3E6 (ATCC No. HB12618), 3G3 (ATCC No. HB-12615), or 4A10 (ATCC No. HB-12617), or fragment thereof that recognizes and binds PSCA as shown in SEQ ID NO:2, in an amount effective to inhibit the growth of the bladder cancer cell.