Patent ID: 7414157
Filing Date: 2008-08-19
Classification: B01J,C07B,C07C,C07D

Abstract:
1. A process for preparing a compound of Formula I that is achiral, racemic or enantiomerically enriched at the hydroxylation center indicated by * wherein R R R R R comprising: contacting a compound of Formula II wherein R wherein the zirconium complex comprises zirconium and a chiral ligand of Formula III or the zirconium complex comprises zirconium and a chiral ligand of Formula ent-III wherein J is an optionally substituted linking chain of 2 to 4 members consisting of at least one carbon atom member and optionally one member selected from nitrogen and oxygen, of which no more than two carbon atom members are substituted as C(═O); the linking chain optionally fused through adjacent linking chain members to 1 or 2 rings or ring systems selected from the group consisting of a C each R when two R each n is independently an integer from 0 to 4.