Patent ID: 6046043
Filing Date: 2000-04-04
Classification: C07D

Abstract:
A method which comprises the steps of: oxidizing a substrate containing an .alpha., .beta.-saturated carbonyl compound with a catalyst system comprising(1) a cofactor of the formula: ##STR37## where R.sup.1 is --CN or --COOR and R.sup.2 is C.sub.1-6 alkyl; bound to (2) an apoflavoprotein in a solvent containing oxygen for a time sufficient to convert the .alpha.,.beta.-saturated carbonyl compound to an .alpha.,.beta.-unsaturated carbonyl compound, andisolating a product containing an .alpha.,.beta.-unsaturated carbonyl compound;wherein said .alpha.,.beta.-saturated carbonyl compound is an aldehyde, ketone, ester, or amide.