Patent ID: 6506402
Filing Date: 2003-01-14
Classification: A23K,C12P

Abstract:
An animal feed composition comprising complexed chlortetracycline in a solid carrier, said solid carrier comprising fermentation solids derived from a fermentation broth produced by fermentation of an organism producing chlortetracycline, wherein said animal feed composition is prepared by:(a) providing first and second quantities of fermentation broth comprising chlotetracycline, said first and second quantities of fermentation broth produced by fermentation of an organism producing chlortetracycline, said first and second quantities of fermentation broth comprising fermentation solids and liquids; (b) adjusting the pH of the first quantity of fermentation broth to a value of about 7 or greater to produce fermentation broth containing chlortetracycline; (c) lowering the pH of said second quantity of fermentation broth to a level sufficient to dissolve the chlortetracycline in said second quantity of fermentation broth; (d) removing solids from said pH-adjusted second quantity of fermentation broth and collecting liquid containing dissolved chlortetracycline; (e) adjusting the pH of said liquid containing dissolved chlortetracycline to a value of about 7 or greater to produce a suspension; (f) mixing said fermentation broth containing complexed chlortetracycline from step (b) and said suspension from step (e); (g) removing liquids from the mixture to produce a chlortetracycline containing fermentation product having a low moisture content; and (h) sizing said low moisture content fermentation product to produce a particulate chlortetracycline-containing fermentation product having a predetermined particle size or range of particle sizes.