Patent ID: 6416510
Filing Date: 2002-07-09
Classification: A61B,A61K,A61M,A61N,B82Y

Abstract:
The method of delivery of a therapeutic agent selected from the set of macromolecule, gene therapy preparation, microspheres, or micelles to a depth within the myocardium including the steps of:providing a catheter adapted for insertion into the heart, said catheter having a proximal end and a distal end, said catheter having a fixating penetrating element secured to the distal end thereof, said catheter having a drug delivery lumen extending from the proximal end to the distal end of the catheter and a drug delivery port at the distal end of the catheter communicating from the drug delivery lumen to the exterior of the catheter; inserting the catheter into the heart, and manipulating the fixating penetrating element to engage the heart wall and releasably connect the catheter distal tip to the heart wall; manipulating the fixating penetrating element to cause it to penetrate the heart wall; and infusing the therapeutic agent to a depth within the heart wall.