Patent ID: 6410318
Filing Date: 2002-06-25
Classification: A61K,A61P,C07K

Abstract:
A method for treating a viral infection, comprising administering to a patient an effective amount of an antibody having a binding affinity to an antigenic epitope on a complex formed between two members of a binding couple, wherein said antigenic epitope is a member of a group consisting of:(i) an epitope consisting of a sequence in a member of a binding couple, which becomes substantially more accessible to antibodies or resumes a new conformation after binding of the two members to one another, (ii) an epitope consisting of two or more sequences in a member of binding couple which upon binding of the two members, become closely associated to form an antigenic epitope, and (iii) an epitope consisting of two or more sequences, at least one being in one member of a binding couple, and at least one other being in the other member of the binding couple and upon binding of the two members, said two or more amino acid sequences become closely associated with one another to form an antigenic epitope; said antigenic epitope being immunogenic.