Patent ID: 6197592
Filing Date: 2001-03-06
Classification: G01N,Y10T

Abstract:
A control material for the detection of a bone resorption marker selected from the group consisting of deoxypyridinoline, pyridinoline, C-telopeptide and N-telopeptide in human urine, said control material prepared by a process comprising:(a) selecting an aliquot of human urine that contains a detectable amount of said bone resorption marker;(b) adjusting the pH of said aliquot to a value within the range of about 7.8 to about 8.5; and(c) lyophilizing said selected aliquot and reconstituting said aliquot thus lyophilized by dissolving in water to form a clear solution containing substantially the same amount of said bone resorption marker as said aliquot of human urine.