Patent ID: 6579460
Filing Date: 2003-06-17
Classification: A61M,B01J,Y10S

Abstract:
A process for removing toxins from a fluid selected from the group consisting of blood and a dialysate solution, the process comprising directly or indirectly contacting the fluid with a shaped ion exchange composite at ion exchange conditions thereby providing a purified fluid, the composite comprising a mixture of a microporous cation exchange composition and an anion exchange composition, where the cation exchange composition is selected from the group consisting of zirconium metallate, titanium metallate and mixtures thereof, the metallates respectively having an empirical formula on an anhydrous basis of:ApMxZr1âˆ’xSinGeyOmâ€ƒâ€ƒ(I) orApMxTi1âˆ’xSinGeyOmâ€ƒâ€ƒ(II) where A is an exchangeable cation selected from the group consisting of potassium ion, sodium ion, calcium ion, magnesium ion and mixtures thereof, M is at least one framework metal selected from the group consisting of hafnium (4+), tin (4+), niobium (5+), titanium (4+), cerium (4+), germanium (4+), praseodymium (4+), and terbium (4+), except that M is not titanium in formula (II), â€œpâ€  has a value from about 1 to about 20, â€œxâ€  has a value from zero to less than 1, â€œnâ€  has a value from 0 to about 12, â€œyâ€  has a value from 0 to about 12, â€œmâ€  has a value from about 3 to about 36 and 1&lE;n+y&lE;12, and the anion exchange composition is selected from the group consisting of hydrous zirconium oxide, zirconia, alumina, titania, hydrous titanium oxide, layered double hydroxides, single phase metal oxide solid solutions, magnesium hydroxide, calcium hydroxide, silica, amorphous mixed metal oxides, basic clays and mixtures thereof.