Patent ID: 7498317
Filing Date: 2009-03-03
Classification: A61K,A61P

Abstract:
1. An antibacterial agent having a chemical structure comprising a sulfated polysaccharide or an oligosaccharide prepared by partial decomposition of said sulfated polysaccharide and an antibacterial substance chemically bonded to the reduced end of said sulfated polysaccharide or of said oligosaccharide, wherein said sulfated polysaccharide or said oligosaccharide prepared by partial decomposition of said sulfated polysaccharide is selected from the group consisting of fucoidan, oligofucose prepared by partial decomposition of fucoidan, carrageenan and carrabiose prepared by partial decomposition of carrageenan, and wherein said chemical structure is represented by either one of the following formulae: wherein Y represents said sulfated polysaccharide or said oligosaccharide prepared by partial decomposition of the sulfated polysaccharide; A represents a carbon derived from an aldehyde group occurring through the reduction of the reduced end sugar of Y and subsequent oxidation of the resulting product with an oxidant; B represents a carbon derived from the aldehyde group at the reduced end sugar of Y; R represents an antibacterial substance with a primary amino group or with an amino group introduced therein or represents an antibacterial substance derivative prepared by bonding an antibacterial substance through a spacer to the carbon A or the carbon B; and n=1 or 2.