Patent ID: 8057796
Filing Date: 2011-11-15
Classification: A61K,A61P,C07K,C12N,G01N

Abstract:
1. An isolated fully human anti-matrix 2 ectodomain (M2e) antibody, where in the M2e is of an influenza A virus, and wherein said antibody comprises a VH CDR1 region comprising the amino acid sequence of NYYWS (SEQ ID NO: 72); a VH CDR2 region comprising the amino acid sequence of FIYYGGNTKYNPSLKS (SEQ ID NO: 74); a VH CDR3 region comprising the amino acid sequence of ASCSGGYCILD (SEQ ID NO: 76); a VL CDR1 region comprising the amino acid sequence of RASQNIYKYLN (SEQ ID NO: 59); a VL CDR2 region comprising the amino acid sequence of AASGLQS (SEQ ID NO: 61); and a VL CDR3 region comprising the amino acid sequence of QQSYSPPLT (SEQ ID NO: 63).