Patent ID: 7993674
Filing Date: 2011-08-09
Classification: A61K,B65B

Abstract:
1. A method for the concomitant formation and packaging of a dosage unit of at least one systemically active pharmaceutical agent as an orally administrable, solid, said method comprising: a. providing a sheet of packaging material having at least one depression therein said packaging material comprising at least a thermoformable plastic; b. providing a flowable composition comprising said at least one pharmaceutical agent, at least one pharmaceutically acceptable non-volatile material which comprises a film-forming substance and a volatile liquid carrier medium in which the pharmaceutical agent(s) and non-volatile material are dissolved or dispersed; c. depositing said composition in said at least one depression; d. subjecting said deposited composition to radiant energy, comprising at least infrared energy, said radiant energy being effective to volatilize said liquid carrier medium, thereby forming said dosage unit as a solid film matrix comprising said non-volatile material, said film matrix including said at least one pharmaceutical agent, the radiant energy being selected to effect preferential absorption by the deposited composition without compromising the packaging material; and e. affixing a lidding sheet to said sheet of packaging material to seal said solid dosage unit within said depression thereby producing a packaged dosage unit of said at least one pharmaceutical agent.