Patent ID: 8426420
Filing Date: 2013-04-23
Classification: A61P,C07D

Abstract:
1. A compound of Formula (I), wherein E is 3- to 10-membered heterocyclic residue selected from azetidine, piperazine, piperidine or pyrrolidine, wherein said heterocyclic residue is bond by its nitrogen atom to the carbonyl carbon atom and wherein said heterocyclic residue is unsubstituted or mono- or disubstituted independently of one another by R3, D is phenyl, wherein phenyl is unsubstituted or substituted 1 or 2 times by R4, Q is 1) a covalent bond, J is 1) hydrogen atom, Z-A-B together with the carbonyl carbon atom form a residue selected from —O—CH V is heterocyclyl selected from azetidinyl, piperazinyl, piperidinyl or pyrrolidinyl, and is unsubstituted or mono- or di-substituted independently of one another by R14, G is 1) a covalent bond, M is 1) hydrogen atom, R1 and R2 are each hydrogen atom, R3 is 1) hydrogen atom, R4 is hydrogen atom or halogen, R10 is hydrogen atom or —(C R11 and R12 are independently of one another identical or different and are 1) hydrogen atom, 2) —(C 3) —(C 4) —(C R11 and R12 form together with the nitrogen atom to which they are attached a heterocyclic ring selected from azetidine, piperidine or pyrrolidine, and wherein said ring is unsubstituted or substituted depending on the number of ring atoms one, two, three or four times by R13, R13 is halogen, —OH, —(C R14 is —(C in all its stereoisomeric forms and mixtures thereof in any ratio, and its physiologically tolerable salts.