Patent ID: 9173835
Filing Date: 2015-11-03
Classification: A61K,A61P

Abstract:
1. A stable pharmaceutical composition for topical application, comprising calcipotriol at a concentration of about 50 μg/g; nicotinamide at a concentration of about 2 to about 20 mg/g; about 0.1 to about 1% (w/w) vitamin E; and a polyethylene glycol-based dermatologically acceptable carrier comprising a mixture of PEG-4000, PEG-400 and polyoxyethylated stearyl alcohol (Steareth-20), wherein the PEG-400 comprises about 70% to about 80% (w/w) of the composition and the PEG-4000 comprises about 15% to about 25% (w/w) of the composition.