Patent ID: 7235403
Filing Date: 2007-06-26
Classification: A61K,A61P,C07K,C12Q,G01N

Abstract:
1. A method for identifying a compound that inhibits growth of a mammalian cell, the method comprising the steps of: (a) culturing a cell in the presence or absence of the compound; (b) assaying the cell for expression or activity of L1CAM (L1 cell adhesion molecule, ICAM2 (intercellular cell adhesion molecule-2), NIN283, ATF4, Zinedin, GBC-1 (Growth of Breast Carcinoma 1), GBC-3 (Growth of Breast Carcinoma 3), and GBC-11 (Growth of Breast Carcinoma 11); and (c) identifying the compound when expression or activity of L1CAM (L1 cell adhesion molecule), ICAM2 (intercellular cell adhesion molecule-2), NIN283, ATF4, Zinedin, GBC-1 (Growth of Breast Carcinoma 1), GBC-3 (Growth of Breast Carcinoma 3), or GBC-11 (Growth of Breast Carcinoma 11) is lower in the presence of the compound than in the absence of the compound.