Patent ID: 6333434
Filing Date: 2001-12-25
Classification: C07C

Abstract:
A process for preparing trifluoromethylanilines of formula (I) ##STR5##whereinR.sup.1 is hydrogen, fluorine, chlorine, bromine, methyl, monochloromethyl, dichloromethyl, or formyl, andR.sup.2 is hydrogen, fluorine or chlorine,with the proviso that when R.sup.1 and R.sup.2 are both hydrogen, the amino group is para to the trifluoromethyl group, comprising(a) nitrating a benzotrichloride of formula (II) ##STR6##wherein R.sup.1 and R.sup.2 are each as defined for formula (I), thereby forming a nitrobenzotrichloride,(b) converting the trichloromethyl group of the nitrobenzotrichloride into a trifluoromethyl group by reaction with anhydrous hydrofluoric acid, thereby forming a nitrobenzotrifluoride, and(c) reducing the nitro groups of the nitrobenzotrifluoride to form a trifluoromethylaniline of formula (I).