Patent ID: 8476307
Filing Date: 2013-07-02
Classification: A61K,C07D

Abstract:
1. A pharmaceutical composition comprising 5 to 25% of a salt of idazoxan, 10 to 40% of microcrystalline cellulose, 0.1 to 5% of lubricant, 0.1 to 0.5% of colloidal silica and 25% to 90% of lactose, with respect to the total mass; wherein said idazoxan is a polymorph of form VI having an X-Ray diffraction pattern comprising characteristic peaks at 5.6150, 6.7350, 7.5350, 9.5250, 10.3450, 10.6050, 11.0350, 11.2850, 11.5350, 12.1150, 12.3750, 12.9550, 13.5150, 13.9950, 14.5250, 14.9350, 15.0450, 15.1950, 16.3450, 17.0450, 17.2850, 17.5750 and 17.8250 degrees θ; and a differential thermal analysis thermogram exhibiting a single maximum value at approximately 208.1+1.0.