Patent ID: 7338947
Filing Date: 2008-03-04
Classification: A61P,C07D

Abstract:
1. A compound of formula (I): or a stereoisomer or a pharmaceutically acceptable salt thereof, wherein: ring B is a cyclohexyl group; ring B being substituted with 0-2 R X is selected from O or S; Z is selected from a bond, —NR wherein neither Z nor R bond (a) is a single or double bond; E is selected from —S(O) R R R R R R R R R R R R, at each occurrence, is selected from H, C R alternatively, two R 6 on adjacent atoms on R 1 may join to form a cyclic acetal; R R R R R R R alternatively, two R R R R R R R R′, at each occurrence, is selected from H, C R R R R R R R R R R R R R R R R R R R R R R alternatively, two R R alternatively, two R R R R R l is selected from 1, 2 and 3; n is 1; m is 0; p, at each occurrence, is independently selected from 0, 1, and 2; q, at each occurrence, is independently selected from 1, 2, 3, and 4; r, at each occurrence, is independently selected from 0, 1, 2, 3, and 4; t, at each occurrence, is independently selected from 2, 3, and 4; s is selected from 0 and 1.