Patent ID: 8178662
Filing Date: 2012-05-15
Classification: A61K,A61P,C07K,C12N,C12Q,Y10T

Abstract:
1. A method of identifying a nucleotide sequence variant of SEQ ID NO: 8, or its complementary sequence comprising (a) isolating genomic DNA from a subject and (b) determining the presence or absence of a variant in said genomic DNA using a nucleic acid molecule comprising at least 20 contiguous nucleotides of an intron region of SEQ ID NO:8, wherein said intron region is selected from the group consisting of the sequence of nucleotides between positions 9015-10,641, 8122-8672, 7932-8049, 7754-7859, 7554-7628, 6662-7475, 6452-6583, 6273-6375, 5456-6218, 5353-5434, 4834-5211, 4647-4749, 4407-4502, 4053-4319, 3707-3929, 3418-3508, 3001-3237, 2570-2650, 2305-2425 and 1967-2208 of SEQ ID NO:8, or its complementary sequence.