Patent ID: 7446127
Filing Date: 2008-11-04
Classification: A61P,C07D

Abstract:
1. A compound having the Formula I: wherein R 1 , R 1 ′, R 2 , R 3 and R 3 ′ are independently selected from H, C 1-7 alkyl, C 2-7 alkenyl, C 2-7 alkynyl, and halogen, wherein alkyl, alkenyl and alkynyl are linear or branched and are optionally substituted with substituents selected from 1 to 7 halogen atoms and 1-3-OC 1-3 alkyl groups; R 4 and R 5 are independently selected from H, halogen, C 1-7 alkyl, C 2-7 alkenyl, C 2-7 alkynyl, —OH, and —OC 1-5 alkyl; R 6 and R 7 are independently selected from H, C 1-7 alkyl, C 2-7 alkenyl, C 2-7 alkynyl and an optionally substituted phenyl; Y is ═O; W is selected from the group of consisting of —OR a , —NR a R b , —NR a SO 2 R b wherein R a and R b are independently selected from the group consisting of H, C 1-4 alkyl and aryl where in all instances, alkyl is linear or branched and are optionally substituted with 1-7 halogen atoms; m and n are independently 0-6; and pharmaceutically acceptable salts thereof.