Patent ID: 6783770
Filing Date: 2004-08-31
Classification: A61K,C08F

Abstract:
A hard capsule shell comprising(A) polymers produced by free-radical polymerization of a) at least one vinyl ester of C1-C24-carboxylic acids in the presence of b) polyether-containing compounds of formula I R1&Parenopenst;Oâ€”R2â€”O)uâ€”(R3â€”O)vâ€”(R4â€”O)w&Brketopenst;Aâ€”R2â€”O)xâ€”(R3â€”O)yâ€”(R4â€”O)z&Brketclosest;sR5)n in which the variables have, independently of one another, the following meaning: R1 hydrogen, C1-C24-alkyl, R6â€”C(&boxH;O)â€”, R6â€”NHâ€”C(&boxH;O)â€”, polyalcohol residue; R5 hydrogen, C1-C24-alkyl, R6â€”C(&boxH;O)â€”, R6â€”NHâ€”C(&boxH;O)â€”; R2 to R4 â€”(CH2)2â€”, â€”(CH2)3â€”, â€”(CH2)4â€”, â€”CH2â€”CH(R6)â€”, â€”CH2â€”CHOR7â€”CH2â€”; R6 C1-C24-alkyl; R7 hydrogen, C1-C24-alkyl, R6â€”C (&boxH;O)â€”, R6â€”NHâ€”C(&boxH;O)â€”; A â€”C(&boxH;O)â€”O, â€”C(&boxH;O)â€”Bâ€”C(&boxH;O)â€”O, â€”C (&boxH;O)â€”NHâ€”Bâ€”NHâ€”C(&boxH;O)â€”O; B â€”(CH2)tâ€”, arylene, optionally substituted; n 1 to 1000; s 0 to 1000; t 1 to 12; u 1 to 5000; v 0 to 5000; w 0 to 5000; x 0 to 5000; y 0 to 5000; z 0 to 5000, and c) at least one other copolymerizable monomer c) selected from the group consisting of tert-butyl acrylate, methyl methacrylate, ethyl methacrylate, isobutyl acrylate, tert-butyl methacrylate, styrene, vinyl chloride, acrylic acid, methacrylic acid, acrylamide and methacrylamide, and subsequent at least partial hydrolysis of the ester functions in the original monomers a), (B) optionally, structure-improving auxiliaries and (C) optionally other constituents selected from the group consisting of fillers, release agents, flow aids, stabilizers, water-soluble or water-insoluble dyes, flavorings and sweeteners.