Patent ID: 6958391
Filing Date: 2005-10-25
Classification: C07H

Abstract:
1. A method of purifying a 5′ protected 2′-deoxypurine nucleoside, which comprises the steps of: (a) preparing a solution of a compound represented by the following formula (1): wherein R 1 represents a 4-methoxytrityl group, 4,4′-dimethoxytrityl group or triphenylmethyl group, and B represents a purine group wherein an amino group is protected; in a liquid medium comprising a solvent for forming inclusion crystals comprising said solvent and the compound of formula (1); (b) forming inclusion crystals comprising said solvent and the compound of formula (1) in said solution by treating said solution alone; and (c) recovering said inclusion crystals from the liquid medium of the solution.