Patent ID: 6482781
Filing Date: 2002-11-19
Classification: A61L

Abstract:
A multi-purpose solution for contact lens care comprising:an aqueous liquid medium; polyhexamethylene biguanide present in an amount in a range of about 0.1 ppm to less tha 5 ppm; a poly (oxyethylene)-poly (oxypropylene) block copolymer surfactant in an amount effective in cleaning a contact lens contacted with said solution; a phosphate buffer component in an amount effective in maintaining the pH of said solution within a physiologically acceptable range; hydroxypropylmethylcellulose in an amount effective in increasing the viscosity of said solution; an effective amount of a chelating component selected from the group consisting of ethylenediaminetetraacetic acid, alkali metal salts of ethylenediaminetetraacetic acid and mixtures thereof in a range of less than 0.05% (w/v); and a tonicity component, including chloride, in an amount effective in providing the desired tonicity to said solution, said solution being preferred for overall performance relative to another multi-purpose solution containing an aqueous liquid medium, 0.5 ppm polyhexamethylene biguanide, a poly(oxyethylene)-poly (oxypropylene) substituted ethylenediamine surfactant, a borate buffer system, 0.1% w/v disodium EDTA and a sodium chloride tonicity agent in a randomized, double masked, three-way crossover study.