Patent ID: 9217032
Filing Date: 2015-12-22
Classification: A61K,A61P,C07K,G01N

Abstract:
1. A method for treating metastatic colorectal cancer, comprising the step of administering to a human patient in need of treatment for metastatic colorectal cancer a therapeutically effective amount of a composition comprising an anti-hPG antibody, wherein said anti-hPG antibody is a monoclonal antibody that binds to human progastrin polypeptide (hPG) having an amino acid sequence of SEQ ID NO:101 but does not detectably bind to an amidated gastrin 17 consisting of SEQ ID NO:104, a glycine-extended gastrin 17 consisting of SEQ ID NO:105, or C-terminal Flanking Peptide (CTFP) consisting of SEQ ID NO:106, in which the anti-hPG antibody is a C-terminal anti-hPG antibody.