Patent ID: 6281219
Filing Date: 2001-08-28
Classification: A01N,C07D

Abstract:
A compound of Formula I ##STR48##whereinR.sub.1 is hydrogen, (C.sub.1-6)alkylthio, halo(C.sub.1-6)alkylthio (C.sub.1-6)alkylsulphinyl, halo(C.sub.1-6)alkylsulphinyl, (C.sub.1-6)alkylsulphonyl, halo(C.sub.1-6)alkylsulphonyl or NR.sub.12 R.sub.13 ;R.sub.12 and R.sub.13 are each independently hydrogen,(C.sub.1-6)alkyl, or halo(C.sub.1-6)alkyl;R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9 and R.sub.11 are each independently selected from hydrogen, halogen, cyano, nitro, (C.sub.1-6)alkyl, halo(C.sub.1-6)alkyl, (C.sub.1-6)alkoxy, halo(C.sub.1-6)alkoxy, (C.sub.1-6)alkoxy(C.sub.1-6)alkyl, halo(C.sub.1-6)alkoxy(C.sub.1-6)alkyl, (C.sub.1-6)alkylthio, halo(C.sub.1-6)alkylthio, (C.sub.1-6)alkyl sulphinyl, halo(C.sub.1-6)alkylsulphinyl, (C.sub.1-6)alkylsulphonyl, halo(C.sub.1-6)alkylsulphonyl, amino, (C.sub.1-6)alkylamino, di(C.sub.1-6)alkylamino, halo(C.sub.1-6)alkylamino,(C.sub.1-6)alkylhaloalkyl(C.sub.1-6 amino, dihalo(C.sub.1-6)alkylamino, (C.sub.1-6)alkyloxy-carbonyl, halo(C.sub.1-6)alkyloxycarbonyl, (C.sub.2-6)alkenyl, halo(C.sub.2-6)alkenyl, (C.sub.2-6)alkynyl, halo(C.sub.2-6)alkynyl;R.sub.10 is halogen, halo(C.sub.1-6)alkyl, halo(C.sub.2-6)alkenyl or halo(C.sub.2-6)alkynyl;and X.sub.1 and X.sub.2 are independently selected from the group consisting of NR.sub.14, NR.sub.15, O, CH.sub.2, CR.sub.18 R.sub.19, CO, C.dbd.NOR.sub.20 ;wherein R.sub.14 is (C.sub.1-6)alkyl;R.sub.15 is H, (C.sub.1-6)alkyl or CH(OR.sub.16)(OR.sub.17);R.sub.16 and R.sub.17 are each independently (C.sub.1-6)alkyl;R.sub.18 and R.sub.19 each independently selected from H, (C.sub.1-6)alkyl, (C.sub.2-6)alkenyl and (C.sub.2-6)alkynyl which are all optionally substituted by one or more halogens which are the same or different, or R.sub.18 and R.sub.19 may together form a carbocyclic ring which is optionally substituted by one or more halogens which are the same or different;R.sub.20 is (C.sub.1-6)alkyl;with the proviso that X.sub.1 cannot be the same as X.sub.2, and with the proviso that the compound of formula 1 is not 4-[m-(trifluoromethyl)benzyl]-]6-(.alpha.,.alpha.,.alpha.-trifluoro-N-meth yl-m-toluidino)pyrimidine.