Patent ID: 7109316
Filing Date: 2006-09-19
Classification: A61P,C07H

Abstract:
1. An OTNTP comprising the structure wherein R and R′ independently represent H, OH, OCH X represents O, S, CH Base represents uracil, cytosine, thymine, adenine, guanine, hypoxanthine, 2-aminopurine, 2,6-diaminopurine, xanthene, deazaadenine, deazaguanine or an analog thereof; Linker represents a linear or branched alkynyl, alkenyl, alkyl, alkylaryl, aryl, or arylalkyl containing one or more heteroatoms selected from the groups consisting of N, O, S and P, and is attached to the base; N represents a ribose, deoxyribose, a natural or unnatural deoxyribonucleoside or a natural or unnatural ribonucleoside, wherein one or more of the N's is labeled with a fluorescent dye; n represents an integer from 10 to 100; and wherein each N is linked to at least one other N by phosphodiester, phosphorothioate, alkyl phosphonate, or other linkages.