Patent ID: 6472535
Filing Date: 2002-10-29
Classification: C07D

Abstract:
A process for preparing a triazolinone of the formula: whereinR1 represents alkyl having 1 to 6 carbon atoms which is optionally substituted by halogen, cyano or C1-C4 alkoxy, or represents cycloalkyl having 3 to 6 carbon atoms which is optionally substituted by halogen, cyano or C1-C4-alkyl, and R2 represents amino, or a radical selected from the group consisting of alkyl, alkenyl, alkinyl, alkoxy, alkylamino or dialkylamino, each or which has up to 6 carbon atoms in the alkyl, alkenyl or alkinyl groups and each of which is optionally substituted by halogen, cyano or C1-C4-alkoxy, or represents a radical selected from the group consisting of C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C2-alkyl or phenyl, each of which is optionally substituted by halogen, cyano, C1-C4-alkyl, C1-C4-alkoxy or C1-C4-alkoxycarbonyl, comprising the steps of mixing a triazolinethione of the formula wherein R1 and R2 are as defined above in this claim 1,with an oxidant at a temperature range of from about 60Â° C. to about 100Â° C. in the presence of a base; and reacting the mixture of said triazolinethione, said oxidant and said base for a time of from about 1 hour to about 6 hours, at a molar ratio of triazolinethione to oxidant to base of from about 1:5:4 to about 1:20:10, wherein said mixture of said triazolinethione, said oxidant and said base has a basic pH in the range of about 10 to 14 and wherein said triazolinone is formed without changing said mixture to an acidic pH.