Patent ID: 6180677
Filing Date: 2001-01-30
Classification: A61K

Abstract:
A method of treating epilepsy, the method comprising administering to a mammal having epilepsy a therapeutically effective amount of a compound of formula I ##STR26##and pharmaceutically acceptable salts, esters, and pro-drugs thereof, wherein;R.sup.1 and R.sup.2 are independently H, phenylcyclopentylcarbonyl, C.sub.1 -C.sub.7 alkyl, cyclohexylmethyl, benzyl, C.sub.1 -C.sub.5 alkylbenzyl, or C.sub.1 -C.sub.5 alkoxybenzyl;A is --C(O)-- or --CH.sub.2 --;R.sup.3 is H or --CH.sub.3 ;R.sup.4 is C.sub.1 -C.sub.4 alkyl or piperidin-1-ylethyl;R.sup.5 is phenyl-(CH.sub.2).sub.n --, C.sub.1 -C.sub.4 alkylphenyl-(CH.sub.2).sub.n --, or halophenyl-(CH.sub.2).sub.n --; andn is 1 or 2.