Patent ID: 6890934
Filing Date: 2005-05-10
Classification: A61P,C07D

Abstract:
1. A sulfonamide compound of formula (I): wherein R (1) aryl, (2) pyrrolyl, pyrrolidinyl, oxazolidinyl, thienyl, or furanyl, each of which may be optionally substituted by oxo or halogen, (3) halogen, (4) halo(lower)alkyl, (5) lower alkoxy optionally substituted by cyclo(lower)alkyl, (6) amino optionally substituted by at least one substituent selected from the group consisting of lower alkyl optionally substituted by cyclo(lower)alkyl, protected carboxy, acyl, lower alkylcarbamoyl, and lower alkanesulfonyl, (7) nitro and (8) lower alkynyl optionally substituted by aryl; R R R a lower alkenyl optionally substituted by aryl or unsaturated 5- or 6-membered heteromonocyclic group having 1 to 4 nitrogen atom(s), aryl optionally substituted by carboxy or protected carboxy, lower alkyl optionally substituted by acyloxy, amino optionally substituted by lower alkyl, or unsaturated 5- or 6-membered heteromonocyclic group having one sulfur atom or one oxygen atom optionally substituted by halogen; and A is a lower alkylene; or a salt, solvate, or hydrate of a compound of formula (I), with the proviso that A is not methylene and R  wherein X is halogen, Y is C or N, and R