Patent ID: 8309112
Filing Date: 2012-11-13
Classification: A61F,A61L,A61P

Abstract:
1. A medical article, comprising an implantable substrate and a coating disposed at least on a portion of the substrate, the coating including an amphiphilic copolymer comprising at least one hydrophobic moiety and at least one hydrophilic moiety, wherein at least one hydrophilic moiety comprises 2-acrylamido-2-methyl-1-propanesulfonic acid, 3-sulfopropyl acrylate, 3-sulfopropyl methacrylate, or 3-allyloxy-2-hydroxypropanesulfonic acid, and wherein the coating includes a therapeutic agent incorporated or dispersed in the coating in a mass ratio of the therapeutic agent to the amphiphilic copolymer between about 1:10 and about 1:3.