Patent ID: 9086425
Filing Date: 2015-07-21
Classification: G01N

Abstract:
1. A method of identifying a subject at risk of experiencing a complication of cardiovascular disease near term, comprising determining a level of peptide bound homocitrulline present in a carbamylated marker in a bodily fluid sample, wherein the carbamylated marker is selected from: carbamylated albumin; carbamylated fibrinogen; carbamylated immunoglobulin; and carbamylated apolipoprotein A, by: wherein the bodily fluid sample is blood, serum, plasma, saliva or urine; and wherein the subject whose level of peptide bound homocitrulline is elevated as compared to a reference value based on a level of peptide bound homocitrulline in a corresponding carbamylated marker in a comparable bodily fluid sample from a reference cohort is at risk of experiencing a complication of cardiovascular disease within an ensuing three years.