Patent ID: 6207649
Filing Date: 2001-03-27
Classification: A61P,C07H,Y02A,Y10S

Abstract:
A pharmaceutical composition comprised of a nucleoside dimer having the formula:R.sub.1 --X--R.sub.2wherein X is a moiety PO.sub.4 or S.dbd.PO.sub.3 ;wherein R.sub.1 and R.sub.2 are the same or different nucleosides;wherein R.sub.1 and R.sub.2 are selected from the group consisting of .beta.-D-deoxyfluorouridine, .alpha.-L-deoxyfluorouridine, .beta.-L-deoxyfluorouridine, .alpha.-L-deoxycytidine, .beta.-L-deoxycytidine, .beta.-L-deoxyuridine, .beta.-L-deoxyguanosine, .beta.-L-deoxyadenosine, .alpha.-L-deoxyadenosine and nitrobenzylthionosine; andwherein R.sub.1 and R.sub.2 are attached to X through --OH groups.