Patent ID: 6018062
Filing Date: 2000-01-25
Classification: A61K,A61P,C07D,C07H,C07J,C07K,Y10S

Abstract:
A 17-Difluoromethylene-estratriene of formula I: ##STR4## wherein R.sup.1 is a hydrogen atom or a C.sub.1 -C.sub.10 alkyl group,R.sup.5 is a methyl or ethyl group, andR.sup.2 is a hydrogen atom or a C.sub.1 -C.sub.10 alkyl group in .alpha.- or .beta.-position,R.sup.3 is a hydrogen atom or a C.sub.1 -C.sub.10 alkyloxy group in .alpha.- or .beta.-position,R.sup.4 is a hydrogen atom in .alpha.- or .beta.-position, andA, B, D, E and A, B, D, E and G each are a hydrogen atom, andoptionally wherein at least one of substituent pairs G and R.sup.2, R.sup.2 and R.sup.4, R.sup.4 and A, A and R.sup.3, B and D, or D and E mean a double bond.