Patent ID: 7371897
Filing Date: 2008-05-13
Classification: C07C

Abstract:
1. A preparation method for (Z)-7-chloro-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoic acid, comprising the steps of: a) Acid-hydrolyzing the ethyl (E)-7-chloro-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoate selectively in the mixture of ethyl (Z)-7-chloro-((S)-2,2-dimethylcyclopropane carboxamido)-2-heptenoate and ethyl (E)-7-chloro-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoate; b) alkali-hydrolyzing obtained ethyl (Z)-7-chloro-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoate in step a) to obtain pure (Z)-7-chloro-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoic acid.