Patent ID: 6514685
Filing Date: 2003-02-04
Classification: A61K,A61P,C07K,G01N,Y10S

Abstract:
A method for detecting cancer in a patient comprising the steps of:obtaining a biological sample selected from the group consisting of ovary, uterus, rectum, brain, liver, blood, serum and bone from the patient; introducing, in vitro, labeled antibodies against alphafetoprotein receptor or labeled alphafetoprotein to said biological sample selected from the group consisting of ovary, uterus, rectum, brain, liver, blood, serum and bone of the patient so the labeled antibodies or labeled alphafetoprotein will react with alphafetoprotein receptor or alphafetoprotein receptor binding sites on the alphafetoprotein receptor for the labeled alphafetoprotein or the labeled antibody in said biological sample; washing away uncomplexed labeled antibody against alphafetoprotein from said biological sample; identifying alphafetoprotein receptor or alphafetoprotein receptor binding sites in said biological sample which have reacted with the labeled antibodies or labeled alphafetoprotein to determine the presence of cancer, wherein an increased level of alphafetoprotein receptor or alphafetoprotein receptor binding sites in relation to normal, non-malignant individuals indicates the presence of cancer.