Patent ID: 7022853
Filing Date: 2006-04-04
Classification: C07D

Abstract:
1. A single pot process for the preparation of zinc and/or chromium nicotinates comprising the steps of: (a) hydrosulfonating beta picoline, by reaction with sulfuric acid at a temperature of about 35-100° C., to form a reaction mixture; (b) further heating the reaction mixture thus obtained to a temperature of about 150°-210° C.; (c) oxidizing the reaction mixture of step (b) with an oxidizing agent to form a solution containing nicotinic acid sulfate at a temperature of about 35-90° C.; (d) adjusting the pH of the solution of step (c) to a basic solution having a pH of about 7 to 8 and maintaining the pH of said solution; (e) treating the basic solution of step (d) with a water soluble zinc and/or chromium salt to produce a solid metal nicotinate in said water, and (f) filtering the resulting solid nicotinate to remove such from said water and to thereby obtain the corresponding metal nicotinates of high purity.