Patent ID: 7456163
Filing Date: 2008-11-25
Classification: A61P,C07D

Abstract:
1. A method of treating Alzheimer's disease (AD), mild cognitive impairment (MCI) and treating or delaying the onset of Alzheimer's disease in those progressing from MCI to AD, or cerebral amyloid angiopathy, the method comprising administering to a patient in need of such treatment a therapeutically effective amount of a compound of the formula or a pharmaceutically acceptable salt thereof wherein U is - - - is an optional bond; J is —CH G is OH when - - - is not a bond or —O— when - - - is a bond; A is selected from where B is aryl or heteroaryl, each of which is optionally substituted with one, two or three groups independently selected from R m is 1-6; R D is —CH X is —NR Y is —(CR Z is O, S, or —NR R R R R R R R R R R R R R R R R R R R R R R R