Patent ID: 8946380
Filing Date: 2015-02-03
Classification: A61K,C07K

Abstract:
1. A liposome comprising: (a) a first liposome membrane component, bound to a first peptide comprising the amino acid sequence of SEQ ID NO:1; (b) a second liposome membrane component bound to one end of polyethylene glycol the other end of which is bound to a second peptide comprising the amino acid sequence of SEQ ID NO:1, and (c) a third liposome membrane component bound to one end of polyethylene glycol the other end of which is bound to the substance capable of binding to a receptor or antigen on the surface of a cell membrane, which liposome is capable of fusing to a cell membrane under acidic conditions, wherein the second peptide is bound via —S— to the other end of polyethylene glycol, and wherein the liposome is capable of releasing into the cytoplasm an entrapped target substance having a molecular weight ranging from low to high.