Patent ID: 7288543
Filing Date: 2007-10-30
Classification: A61P,C07D

Abstract:
1. A compound of formula (I) wherein: j is 1 or 2; y is 0, 1, or 2; and z is 0, 1, or 2; p is 0, 1, or 2; E is O or NH; and wherein each of X R and wherein R R R R wherein each R R R or a compound selected from 8-cyclooctylaminomethyl-10,11-dihydro-dibenzo[b,f]oxepine-2-carboxylic acid amide; 8-cycloheptylaminomethyl-10,11-dihydro-dibenzo[b,f]oxepine-2-carboxylic acid amide; 8-[(cycloheptylmethyl-amino)-methyl]-10,11-dihydro-dibenzo[b,f]oxepine-2-carboxylic acid amide; 8-{[cyclopropylmethyl-(3-methyl-butyl)-amino]-methyl}-10,11-dihydro-dibenzo[b,f]oxepine-2-carboxylic acid amide; 8-[2-(4-chloro-phenyl)-pyrrolidin-1-ylmethyl]-10,11-dihydro-dibenzo[b,f]oxepine-2-carboxylic acid amide; 8-(2-phenyl-azepan-1-ylmethyl)-10,11-dihydro-dibenzo[b,f]oxepine-2-carboxylic acid amide; and 8-(2-benzyl-pyrrolidin-1-ylmethyl)-10,11-dihydro-dibenzo[b,f]oxepine-2-carboxylic acid amide; or a pharmaceutically acceptable salt or solvate thereof.