Patent ID: 6147220
Filing Date: 2000-11-14
Classification: C07C,C07D

Abstract:
A process for the preparation of a 2-substituted-4,4-disubstituted-5-methylene-1,3-oxazoline of formula (I) by cyclization of an alkyl ketone of formula (II) in the presence of an acetylating agent, an acid catalyst, an appropriate solvent or excess acetylating agent, and an appropriate reaction temperature ##STR11## wherein Z is alkyl or substituted alkyl, aryl or substituted aryl, heteroaryl or substituted heteroaryl,R is a hydrogen atom or alkyl, andR.sup.1 and R.sup.2 are each independently an alkyl or substituted alkyl group, or R.sup.1 and R.sup.2 together with the carbon atom to which they are attached form a cyclic structure.