Patent ID: 6218568
Filing Date: 2001-04-17
Classification: C07D,Y02P

Abstract:
The process for preparing a compound of Formula (III) ##STR15##wherein Y.sup.1 is lower acyloxy, Y.sup.2 is aralkyloxy, and Z is lower acyloxy or benzoyloxy, comprising:(a) reacting 1-aralkyloxy-3-halo-2-propanol with methoxymethyl alkanoate in an aprotic solvent in the presence of a catalyst to produce 1-aralkyloxy-3-halo-2-(alkanoyloxy)methoxypropane; and(b) treating the product of step (a) with an alkali metal alkanoate in the presence of a phase transfer catalyst in an aprotic solvent at about 80-120.degree. C. for 6-36 hours.