Patent ID: 7563822
Filing Date: 2009-07-21
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A method for the treatment of a renal disease selected from the group consisting of diabetic nephropathy, IgA nephropathy, membranoproliferative glomerulonephritis, lupus nephritis and purpura nephritis, which comprises administering an effective amount of a 5-amidino-2-hydroxybenzenesulfonamide derivative represented by the general formula: wherein R 1 represents a hydrogen atom or a lower alkyl group which may have a substituent selected from the following group (A); (A) —COOR T represents an oxygen atom, a sulfur atom or a sulfonyl group; or TR R (B) an oxo group, a lower alkyl group, a halo(lower alkyl) group, —Y—R (C) a lower alkyl group, an amino group and —COOR Q represents a hydrogen atom or a lower alkyl group which may have a substituent selected from the following group (D); (D) —OR Z represents a hydrogen atom, a hydroxy group or —COOR wherein R or a pharmaceutically acceptable salt thereof.