Patent ID: 7476682
Filing Date: 2009-01-13
Classification: A61P,C07D

Abstract:
1. A method of inhibiting an activity of a 5HT2A receptor comprising contacting the 5HT2A receptor with an amount of one or more of the compounds of Formula I that is effective in inhibiting the activity of the 5HT2A receptor, wherein the compound of Formula I has the structure: or a pharmaceutically acceptable salt thereof, wherein: R R m is 1; n is selected from the group consisting of 1, 2, and 3; Ar W is selected from the group consisting of oxygen and sulfur; X is selected from the group consisting of optionally substituted methylene, optionally substituted ethylene, optionally substituted propylene, optionally substituted vinylene, and CH Ar is an optionally substituted aryl or heteroaryl.