Patent ID: 6303756
Filing Date: 2001-10-16
Classification: C07K

Abstract:
An isolated antibody or binding fragment thereof which selectively binds a protein encoded by an isolated nucleic acid molecule selected from the group consisting of (a) nucleic acid molecules which hybridize under stringent conditions to a complement of a nucleic acid molecule having a nucleotide sequence set forth as SEQ ID NO:42, and which code for a sarcoma associated gene product, wherein the stringent conditions are hybridization at 65.degree. C. in hybridization buffer (3.5.times.SSC, 0.02% Ficoll, 0.02% polyvinyl pyrrolidone, 0.02% Bovine Serum Albumin, 25 mM NaH.sub.2 PO.sub.4 (pH 7), 0.5% SDS, 2 mM EDTA) and wherein SSC is 0.1 5M sodium chloride/0.015M sodium citrate, pH 7; SDS is sodium dodecyl sulphate; and EDTA is ethylenediaminetetracetic acid, and (b) nucleic acid molecules that differ from the nucleic acid molecules of (a) in codon sequence due to the degeneracy of the genetic code.