Patent ID: 9179845
Filing Date: 2015-11-10
Classification: A61B,G01J,G01N

Abstract:
1. A device for in-depth in vivo observation or diagnostics of a compact biological tissue or a living organ, in particular a tumor, comprising: a probe provided with a proximal end on an operator side and a distal end on the side of the tissue to be observed or diagnosed, and comprising a hollow needle ending at the distal end in a cutting point able to penetrate a surface of the tissue to be observed or diagnosed and to sink within said tissue, wherein the needle includes and integrally surrounds a single optical fiber of the multimode type, the distal end of which has an exact cutting shape of the distal end of the needle and in the continuity of the cutting point of the needle, the distal end of the needle and of the optical fiber having a tapering profile with a single bevel forming an angle with the longitudinal axis of the needle, the angle being between 10° and 25°, wherein the needle surrounds the optical fiber except on the single bevel; and a light injection and recovery means connected to a proximal end of said optical fiber and arranged to inject a feed forward, continuous, low energy light signal into the proximal end of the optical fiber and to receive out of the proximal end of said optical fiber at least one feedback light signal of endogenous fluorescence generated by excitation due to said injected light, said feedback light signal being collected through said bevel of said optical fiber; wherein the light injection and recovery means comprises an analyzing device for measuring said feedback signal, said analyzing device comprising separating means that separate said feedback signal according to a wavelength regardless of time, thus obtaining a steady-state spectral analyzing.