Patent ID: 8475826
Filing Date: 2013-07-02
Classification: A61F,A61K,A61L

Abstract:
1. A method for producing a titanium oxide-organic polymer composite material for artificial bone comprising the steps of: forming a titania solution by adding a solution consisting of acidic alcohol and water into an alcohol solution of titaniumtetraalkoxide, providing an organic polymer base material which includes a polymer selected from the group consisting of polyolefin, polyester and nylon, and does not have an active group selected from the group consisting of hydroxyl groups or derivatives thereof, thiol groups, aldehyde groups and amino groups, forming titania gel on the surface of the base material by dipping the base material into a solution of the titania solution which is at a temperature of 0° C. to 50° C. for several seconds to 1 week, and drying the base material with the titania gel formed on its surface, treating the titania gel that has formed on the surface of the base material by dipping the base material with the titania gel formed on its surface into hot water of 50° C. to 95° C. or a solution of room temperature to 95° C. to which acid is added for an effective period of time to form a titanium oxide membrane on the base material and to obtain the titanium oxide-organic polymer composite material for artificial bone, wherein the titanium oxide membrane has activity to form an apatite in mammalian body fluid, and wherein the apatite has a similar Ca/P atom ratio to an apatite of mammalian bone, with the proviso that an intermediate layer is not formed on the base material by contacting the base material with a silane coupling agent to form an intermediate layer.