Patent ID: 6387619
Filing Date: 2002-05-14
Classification: A61K,C07K,C12N,C12Q

Abstract:
A method of using a DNA segment that comprises an isolated gene associated with non-ciliate telomerase, wherein said DNA segment is characterized as encoding a polypeptide that includes a contiguous amino acid sequence of at least about 17 amino acids from SEQ ID NO:16, SEQ ID NO:18, SEQ ID NO:20, SEQ ID NO:22 or SEQ ID NO:24, or is characterized as specifically hybridizing to the nucleic acid segment of SEQ ID NO:29, SEQ ID NO:30, SEQ ID NO:19, SEQ ID NO:31 or SEQ ID NO:23, or the complement thereof, the method comprising the steps of:(a) preparing a recombinant vector in which a non-ciliate telomerase-associated gene is positioned under the control of a promoter; (b) introducing said recombinant vector into a recombinant host cell; (c) culturing the recombinant host cell under conditions effective to allow expression of the telomerase-associated gene; and (d) collecting the expressed gene product.