Patent ID: 9187560
Filing Date: 2015-11-17
Classification: A61K,A61P,C07K,Y02A

Abstract:
1. A method of treating cachexia, weakness, fatigue, and/or fever in a patient diagnosed with an interleukin-6 (IL-6) associated disorder, comprising administering to the patient an anti-IL-6 antibody or antibody fragment, whereby the patient's cachexia, weakness, fatigue, and/or fever is improved, and monitoring the patient to assess cachexia, weakness, fatigue, and/or fever, wherein the anti-IL-6 antibody or antibody fragment comprises an anti-IL-6 antibody comprising a variable light (VL) polypeptide and a variable heavy (VH) polypeptide respectively comprising the identical CDRs as of (i) SEQ ID NO:85 and 86, or (ii) SEQ ID NO:101 and 102.