Patent ID: 8673876
Filing Date: 2014-03-18
Classification: A61K,A61N,A61P

Abstract:
1. A method of treating or preventing non-small cell lung cancer, breast cancer, thyroid cancer, melanoma, or pancreatic cancer, comprising administering to an individual in need thereof a synergistic combination of a. a therapeutically-effective amount of (S)—N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl) cyclopropane-1-sulfonamide, a salt thereof, or a polymorph thereof; and b. a therapeutically-effective amount of 4-amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl]-1H-pyrimidin-2-one: