Patent ID: 7216039
Filing Date: 2007-05-08
Classification: G01N,Y10T

Abstract:
1. Method for the automatic performance of chromatographic investigations with the help of an electronic data processing apparatus and comprising the steps of: i) Recording of data which include at least one of the following items of information ii) Calculation of retention times as a function of optimizing parameters based on a model which reproduces a functional relationship of at least part of the data recorded under i), the recorded data also being able to be reproduced by setting model parameters, iii) Optimization of the retention times in the model by varying the optimizing parameters. iv) Carrying out at least one further chromatography run with the parameters of the retention times optimized according to step iii), and comparing the actual retention times with the theoretically calculated, optimized retention times, v) Optionally single or repeated repetition of steps i) to iv) if the deviations of the calculated and the measured retention times exceed a presettable limit value or if the differences between the retention times of two successive chromatography runs fall short of a presettable limit value, the decision for parameters to be specifically set for a next run preferably being taken by an artificial intelligence module.