Patent ID: 9034378
Filing Date: 2015-05-19
Classification: A61K,A61L,C08G,C09D

Abstract:
1. A tissue engineering scaffold comprising a cured polyurethane or polyurethane/urea, wherein said polyurethane or polyurethane/urea comprises the reaction product of isocyanate, polyol, a chain extender having a hydrolysable linking group and, optionally, a conventional chain extender, said polyol having a molecular weight of 120 to 400, said chain extender having a hydrolysable linking group is selected from the group consisting of glycolic acid-ethylene glycol dimer, lactic acid-ethylene glycol dimer and trimers of lactic acid and/or glycolic acid and ethylene glycol, the acid number of the polyurethane or polyurethane/urea is about zero, and the tissue engineering scaffold is biocompatible and biodegradable, wherein the polyurethane or polyurethane/urea comprises hard and soft segments and the amount of hard segment is 20 to 70% by weight based on the total weight of the polyurethane or polyurethane/urea.