Patent ID: 9084752
Filing Date: 2015-07-21
Classification: A61K,A61P,C12N

Abstract:
1. A composition for reducing or preventing proliferation or differentiation of multipotent, totipotent, or pluripotent cells in culture comprising viable human multipotent, totipotent, or pluripotent cells and a self-assembled nanofiber scaffold, wherein the nanofiber scaffold is formed from a solution of precursor peptides at a concentration of from 2% to 3% weight to volume, wherein the cells are at a concentration of 1,000 cells/μl to 100,000 cells/μl, and wherein the self-assembling peptide nanofiber scaffold contacts the cells to mimic cell-cell contact and prevent or reduce proliferation or differentiation of the cells for a period of between 1 and 30 days.