Patent ID: 8318790
Filing Date: 2012-11-27
Classification: A61P,C07D

Abstract:
1. A compound represented by the following structural formula: or a tautomer, or a pharmaceutically acceptable salt thereof, wherein: R R R R is selected from one of the following structural formulas: R or two R R Z is a substituent; p, for each occurrence, is independently, 1 or 2; m, for each occurrence, is independently, 1, 2, 3 or 4; n is 0, 1, 2, or 3; and with the proviso that the compound is not 3-(2,4-Dihydroxyphenyl)-4-(1,2,3,4-tetrahydronaphthalen-5-yl)-5-mercapto-[1,2,4]triazole; 4-ethyl-6-(5-mercapto-4-(1-methylindolin-5-yl)-4H-1,2,4-triazol-3-yl)benzene-1,3-diol; or 4-(4-(2,3-dihydro-1H-inden-5-yl)-5-mercapto-4H-1,2,4-triazol-3-yl)-6-isopropylbenzene-1,3-diol.