Patent ID: 8501681
Filing Date: 2013-08-06
Classification: A61K,A61P,C07D

Abstract:
1. A compound of Formula I: or a pharmaceutically acceptable salts thereof, wherein: A is selected from H, —(C═O)—O—R R (i) aryl; substituted aryl; heteroaryl; substituted heteroaryl; (ii) heterocycloalkyl or substituted heterocycloalkyl; and (iii) —C R (i) hydrogen; (ii) aryl; substituted aryl; heteroaryl; substituted heteroaryl; (iii) heterocycloalkyl or substituted heterocycloalkyl; and (iv) —C G is —NHS(O) R (i) hydrogen; (ii) aryl; substituted aryl; heteroaryl; substituted heteroaryl; (iii) heterocycloalkyl or substituted heterocycloalkyl; and (iv) —C L is selected from —CH X and Y taken together with the carbon atoms to which they are attached to form a cyclic moiety selected from aryl, substituted aryl, heteroaryl, and substituted heteroaryl; W is absent, or selected from —O—, —S—, —NH—, —N(Me)—, —C(O)NH—, and —C(O)N(Me)—; alternatively, W is —C Z is selected from the groups consisting of: (i) hydrogen; (ii) —CN; (iii) —N (iv) halogen; (v) —NH—N═CH(R (vi) aryl, substituted aryl; (vii) heteroaryl, substituted heteroaryl; (viii) —C (ix) —C (x) —C (xi) —C j=0, 1, 2, 3, or 4; k=1, 2, or 3; m =0, 1, or 2; and