Patent ID: 7863428
Filing Date: 2011-01-04
Classification: C07H

Abstract:
1. An enzyme substrate of the formula (I): and biologically acceptable salt, and pro-reporter molecules thereof; wherein Y is C═O, and n is 1 or 0; W is —N(R M is oxygen; R R each q is independently 0, 1, 2, 3, or 4; wherein any C wherein the BLOCKING GROUP is α-D-glucose, β-D-glucose, α-D-galactose, β-D-galactose, α-D-glucose, β-D-glucose, α-D-galactose, β-D-galactose, α-D-mannose, β-D-mannose, β-D-N-acetyl-glucosamine, β-D-glucuronic acid, β-D-fucose, α-L-fucose, α-L-iduronic acid, β-D-cellobiose, α-L-arabinose, β-D-xylose, α-D-N-acetyl-neuraminic acid (sialic acid), aryl esters of p-guanidino benzoic acid, aryl or alkyl phosphate monoesters, aryl sulfate monoesters, aryl phosphates-D-mannose, β-D-mannose, β-D-N-acetyl-glucosamine, β-D-glucuronic acid, β-D-fucose, α-L-fucose, α-L-iduronic acid, β-D-cellobiose, α-L-arabinose, β-D-xylose, α-D-N-acetyl-neuraminic acid (sialic acid), aryl esters of p-guanidino benzoic acid, aryl or alkyl phosphate monoesters, aryl sulfate monoesters, or aryl phosphates; with the proviso that at least one R