Patent ID: 8361965
Filing Date: 2013-01-29
Classification: A61K,A61P,C07K

Abstract:
1. A recombinant chimeric protein of neutrophil inhibitory factor (NIF) and hirugen, comprising: (1) the amino acid sequence of Met-NIF-linker 1-FPRP(SEQ ID NO:11)-linker 2-hirugen; (2) the amino acid sequence of NIF-linker 1-FPRP(SEQ ID NO:11)-linker 2-hirugen, or (3) an amino acid sequence that is greater than 90% identical to the sequence of SEQ ID NO:3, including the amino acid sequence FPRPGSGG (SEQ ID NO:21) wherein the recombinant chimeric protein has an activity of treating cardio-cerebrovascular diseases, the linker 1 being 5-15 glycines and the linker 2 being (GSGG)