Patent ID: 6465430
Filing Date: 2002-10-15
Classification: A61K,A61P,C07K

Abstract:
A method of activating a thrombopoietin receptor in a cell, comprising contacting said cell with an effective amount of a peptide having a molecular weight of less than about 8000 daltons, and comprising a sequence of amino acids (SEQ ID NO:2):X1 X2 X3 X4 X5 X6 X7 where X1 is C, L, M, P, Q, V; X2 is F, K, L, N, Q, R, S, T or V; X3 is C, F, I, L, M, R, S, V or W; X4 is any of the 20 genetically coded L-amino acids; X5 is A, D, E, G, K, M, Q, R, S, T, V or Y; X6 is C, F, G, L, M, S, V, W or Y; and X7 is C, G, I, K, L, M, N, R or V.