Patent ID: 8420110
Filing Date: 2013-04-16
Classification: A61K,A61L,A61P

Abstract:
1. A medical device comprising: an expandable member having a first diameter for insertion into a vessel and a second diameter for making contact with the vessel walls; and a liquid formulation of a rapamycin affixed to at least a portion of the surface of the expandable member, the liquid formulation of a rapamycin comprising about 50 mg/ml of a rapamycin, about 5 mg/ml of a first excipient selected from the group of polymers consisting of PEG 400, PEG 1000, PEG 1500, PEG 2000 and polyvinyl alcohol, about 5 mg/ml of a second excipient selected from the group of antioxidants consisting of BHT, BHA and vitamin E TPGS, ascorbyl palmitate, and resveratrol, and acetone and water in a ratio of about 60/40 to about 75/25.