Patent ID: 6348597
Filing Date: 2002-02-19
Classification: A61P,C07C,C07D

Abstract:
A compound of the formula whereinW represents â€”C(&boxH;O)â€” or â€”CH(OH)â€”; R1 represents hydroxy; R2 represents hydrogen; n is an integer 3; m is an integer 0; R5 is â€”CONR6R7 wherein R6 and R7 are each independently H, C1-C6alkyl, C1-C6alkoxy or R6 and R7 taken together with the nitrogen atom form a pyrrolidine, piperidine or morpholine, with the proviso that R6 and R7 cannot both be represented by C1-C6alkoxy and with the further proviso that one of R6 and R7 cannot be C1-C6 alkyl and the other C1-C6 alkoxy; A is hydrogen; and pharmaceutically acceptable salts and individual optical isomers thereof.