Patent ID: 6348591
Filing Date: 2002-02-19
Classification: A61K,A61Q,C07D,C08K

Abstract:
A triazine compound of formula (I), (II) or (III), as follows: whereini is 1 or 2; each X is independently selected from hydrogen, C1-C8 alkyl, halogen-substituted C1-C8 alkyl, allyl, â€”CORa, â€”SO2Rb, â€”SiRcRdRe, â€”PRfRg and â€”PORfRg; each of Y and Z is independently selected from an aryl ring of the formula (IV) â€ƒeach R is independently selected from a hydrogen, a hydrocarbyl group and a functional hydrocarbyl group; each Ra is independently selected from C1-C8 alkyl, halogen-substituted C1-C8 alkyl, C5-C12 cycloalkyl, C2-C8 alkenyl, â€”CH2â€”COâ€”CH3, C7-C12 aralkyl, C1-C12 alkoxy, or phenyl which is unsubstituted or substituted by C1-C12 alkyl, C1-C4 alkoxy, halogen and benzyl; each Rb is independently selected from C1-C12 alkyl, C6-C10 aryl and C7-C18 alkylaryl; each Rc, Rd and Re is independently selected from C1-C18 alkyl, cyclohexyl, phenyl and C1-C18 alkoxy; each Rf and Rg is independently selected from C1-C12 alkoxy, phenoxy, C1-C12 alkyl, C5-C12 cycloalkyl, benzyl, tolyl and phenyl; when i is 1, R1 is bonded to the 3-position of the ring bearing the â€”OX group, R11 is bonded to the 5-position of the ring bearing the â€”OX group, and R11 is R1 and, when i is 2, R1 is bonded, independently, to either the 3-position or the 5-position of a first ring and a second ring bearing the â€”OX group and R11 is bonded, at a first end, to the position of the first ring bearing â€”OX not bonded to R1 and at a second end, to the position of the second ring bearing â€”OX not bonded to R1, and R11 is a hydrocarbylene group of 1 to 24 carbon atoms; each R1, R2, R4, R4â€² and R4â€³ is independently selected from hydrogen, hydrocarbyl, functional hydrocarbyl, â€”O(hydrocarbyl), â€”O(functional hydrocarbyl), â€”SR, halogen, â€”SO2R, â€”SO3R, â€”COOR, â€”COR, â€”OCOR, â€”NRR and cyano; and each R3 is independently selected from R, â€”OR, â€”SR, halogen, â€”SO2R, â€”SO3R, â€”COOR, â€”COR, â€”NRR and cyano; and further wherein at least one 3-position R1 group is independently selected from a group of the formulae (V) and (VI) â€ƒwherein R5 is independently selected from hydrogen, linear or branched hydrocarbyl group of 1 to 24 carbon atoms, phenyl, and aralkyl of 7 to 24 carbon atoms; and each R6 and R7 is independently selected from hydrogen, a hydrocarbyl group and a functional hydrocarbyl group.