Patent ID: 6372470
Filing Date: 2002-04-16
Classification: C12N

Abstract:
An isolated or modified esterase having a thermostable esterase activity, which is obtained by modifying the amino acid sequence shown by SEQ ID NO: 2 and where the modification is selected from any one of the following:(1) an amino acid substitution where the 325th amino acid in the amino acid sequence shown by SEQ ID NO: 2 is substituted with isoleucine; (2) an amino acid substitution where the 240th amino acid in the amino acid sequence shown by SEQ ID NO: 2 is substituted with alanine, and the 288th amino acid is substituted with alanin; and (3) an amino acid substitution where the 43rd amino acid in the amino acid sequence shown by SEQ ID NO: 2 is substituted with serine.