Patent ID: 7087576
Filing Date: 2006-08-08
Classification: A61K,C07K

Abstract:
1. Novel dipeptide phenyl ethers of formula (I) their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates, wherein ---- represents an optional double bond; X and Z may be same or different and independently represent oxygen, sulfur or NR 5 , wherein R 5 represents hydrogen or linear or branched alkyl group provided both X and Z are not same when they represent oxygen or sulfur; Y 1 and Y 2 may be same or different and independently represent oxygen, sulfur or NR 5 , wherein R 5 represents hydrogen or linear or branched alkyl group; R 1 , R 2 , R 3 and R 4 may be same or different and independently represent hydrogen, halogen, hydroxy, nitro, cyano, formyl, mono-, di-, or unsubstituted amino, linear or branched alkyl, linear or branched alkoxy group; A represents oxygen, sulfur or NR, wherein R represents hydrogen or linear or branched alkyl; B represents a bond or substituted or unsubstituted aryl, heterocyclyl or heteroaryl ring of 5 to 14 carbon and hetero atoms; C 1 and C 2 may be same or different and independently represent an amino acid and are linked through —NH— of C 1 and —CO— of C 2 , or through —CO— of C 1 and —NH— of C 2 ; B is directly linked or linked through alkyl or alkylene groups of 1 to 4 carbon atoms to the α-carbon of C 1 .