Patent ID: 7906300
Filing Date: 2011-03-15
Classification: C12Q,G01N

Abstract:
1. A method for diagnosing attention-deficit/hyperactivity disorder (ADHD) in a human patient, comprising: (a) obtaining a ratio of at least one of the following steps (b) or (b′): (b) comparing the ratio obtained in (a) to a control ratio, wherein the control ratio is the ratio of wherein when the ratio obtained in (a) is significantly higher than the control ratio obtained in (b), said test human patient is diagnosed as having ADHD; (b′) comparing the ratio obtained in (a) to a ADHD control ratio, wherein the ADHD control ratio is the ratio of wherein when the ratio obtained in (a) is not significantly different than the ADHD control ratio obtained in (b′), said test human patient is diagnosed as having ADHD, wherein each mean membrane potential is determined by incubating the cells in vitro in buffer comprising a potential-sensitive dye, resuspending the cells in potential-sensitive dye free-buffer, and measuring cell fluorescence.