Patent ID: 7906551
Filing Date: 2011-03-15
Classification: A61P,C07D

Abstract:
1. Compound of Formula I: wherein: the substituent in position 1 of the pyrrole ring is a phenyl, substituted with R′ and R″ groups, independently selected from: hydrogen, fluorine, chlorine, bromine, methyl, trifluoromethyl, methylsulphonyl and aminosulphonyl (SO the substituent R1 in position 2 of the pyrrole ring is methyl, ethyl, isopropyl, n-butyl or isobutyl; the substituent in the position 3 of the pyrrole ring is a two carbon atoms chain, wherein the groups X, Y, Z have the following meanings: provided that: when Y is the C═O group and X is H, Z is not hydroxy; when Y is the C═O group, Z is alkoxy and X is H, R when Z is selected between alkylamido or arylamido (—NHCOR when Z is selected between amino (—NH the group R the R′″ group is independently selected form hydrogen, methylsulphonyl (—SO compounds of Formula I can be chiral compounds, in this case compounds of Formula I can exist as individual enantiomers (S or R) or as mixture of such enantiomers; enantiomers can also exist when Z group is chiral; such enantiomers and their racemic mixtures or enriched mixtures of enantiomers of compounds of Formula I being included; when the X group is not hydrogen, and at the same time the Z group is a chiral, compounds of formula I can exist both as diastereisomers and enantiomers; all the possible diastereoisomers and enantiomers of compounds of Formula I being included.