Patent ID: 8361800
Filing Date: 2013-01-29
Classification: G01N

Abstract:
1. A method of diagnosing initial heart failure as a cause of cardiac necrosis in a human subject suffering from cardiac necrosis, the method comprising the steps of: contacting, in vitro, a portion of a sample from a subject with a ligand comprising specific binding affinity for troponin T; contacting, in vitro, a portion of the sample from the subject with a ligand comprising specific binding affinity for NT-pro BNP; calculating an amount of the troponin T and an amount of NT proBNP based on said steps of contacting; and providing a diagnosis of initial heart failure as the cause of cardiac necrosis if the amount of troponin T is greater than an upper limit of normal for troponin T between 0.001 and 0.01 ng/ml and the amount of NT-proBNP is greater than an upper limit of normal for NT-proBNP between 100 and 150 pg/ml.