Patent ID: 7220781
Filing Date: 2007-05-22
Classification: A61K,C07C,C07D,C07K

Abstract:
1. A serine protease inhibitor compound of formula (I) where R 1 and R 2 each independently is hydrogen or hydroxyl, alkoxy, alkyl, aminoalkyl, hydroxyalkyl, alkoxyalkyl, alkoxycarbonyl, acyloxymethoxycarbonyl or alkylamino optionally substitituted by hydroxy, alkylamino, alkoxy, oxo, aryl or cycloalkyl; each R X-X is —CH═CH—, —CONH—, —CONR L is an organic linker group containing 1 to 5 backbone atoms selected from C, N, O and S, or a branched alkyl or cyclic group; Y is a nitrogen atom or a CR Cy represents a phenyl or naphthyl group optionally substituted by groups R Lp(D) or a physiologically tolerable salt thereof.