Patent ID: 9163077
Filing Date: 2015-10-20
Classification: A61K,A61P,C07K,C12N,C12Y

Abstract:
1. A method of treating a metastatic cancer disease, the method comprising administering to a patient suffering from a metastatic cancer disease, an effective amount of an isolated immunologically active peptide fragment from RhoC of SEQ ID NO:1 consisting of 18 to 25 consecutive amino acids, 8 to 10 consecutive amino acids, or 26 to 60 consecutive amino acids, wherein at the most two amino acids have been substituted, wherein the peptide fragment contains at least one of amino acid residues I43, Q123, R140, S141, S152, L157, E165, G178, V181, K183, N184, R186, R187, R188, P191 or I192 of RhoC of SEQ ID NO:1, and wherein RhoC is expressed in the metastatic cancer disease.