Patent ID: 7384740
Filing Date: 2008-06-10
Classification: A61P,C07K

Abstract:
1. A method of diagnosing autism linked to a mutation in the polynucleotide of SEQ ID NO: 12 or the polypeptide of SEQ ID NO: 14, or a propensity therefor, in a human, wherein said mutation results in altered synapse formation, wherein said method comprises (a) detecting a mutation in wherein said detecting comprises comparing the sequence of the polynucleotide or polypeptide obtained from said human with the polynucleotide of SEQ ID NO: 12 or the polypeptide of SEQ ID NO: 14 and identifying mutations in said polynucleotide or polypeptide from said human; and (b) correlating said mutations in said polynucleotide or polypeptide from said human with a autism or a propensity for autism.