Patent ID: 8344180
Filing Date: 2013-01-01
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A compound of the formula (I): or a pharmaceutically acceptable salt thereof, wherein R R X is optionally substituted cycloalkylene, or —NR wherein a group of the formula: is piperidinediyl, piperazinediyl, pyridindiyl, pyrazinediyl, pyrrolidinediyl or pyrrolediyl, U is a bond, lower alkylene or lower alkenylene, Y is —OCONR R Z is optionally substituted carbocyclyl, or optionally substituted heterocyclyl, W is —S(═O)n-, n is 2, provided that Z is not carbocyclyl substituted with non-halogeno lower alkoxy, and provided that 5-Methyl-4,5,6,7-tetrahydro-thiazolo[5,4-c]pyridine-2-carboxylic acid [2-[(5-chloro-1H-indole-2-carbonyl)-amino]-5-(N′,N′-dimethyl-hydrazinocarbonyl)-cyclohexyl]-amide and 5-Methyl-4,5,6,7-tetrahydro-thiazolo[5,4-c]pyridine-2-carboxylic acid [2-[(5-chloro-4-fluoro-1H-indole-2-carbonyl)-amino]-5-(N′,N′-dimethyl-hydrazinocarbonyl)-cyclohexyl]-amide are excluded.