Patent ID: 7842685
Filing Date: 2010-11-30
Classification: A61K,A61P,C07D

Abstract:
1. A compound of Formula (I): wherein: m is 0, 1, 2 or 3; n is 0, 1, 2 or 3; o is 0, 1, 2 or 3; A is a phenyl, heterocyclyl, three to six membered cycloalkyl, or a five or six membered heteroaryl ring; L is a saturated 3, 4, 5, 6 or 7-member ring containing 0, 1 or 2 atoms selected from N, O and S and optionally containing a double bond, the ring being substituted by 0, 1 or 2 groups selected from F, Cl, C X X X  is selected from R R R Z is: (i) a cycloalkyl substituted with amino, monoalkylamino or dialkylamino group; a cycloalkylalkyl substituted with one or two carboxy groups; a monosubstituted amino, disubstituted amino, carboxyalkylamino, hydroxyalkyl, substituted hydroxyalkyl, hydroxyalkoxy, substituted hydroxyalkoxy, aminoalkyl, aminoalkoxy, carboxyalkyl, substituted carboxyalkyl, carboxyalkyloxy, substituted carboxyalkyloxy, carboxyalkoxyalkyl, substituted carboxyalkoxyalkyl, aminocarbonyl, acylamino, aminosulfonyl, sulfonylamino, heterocycloamino, heterocycloaminoalkyl, heterocycloaminocarbonyl, heterocycloaminooxy, or heteroaralkyl group; (ii) a group of formula (b): where: R R R R R R R R each R (iii) when R a pharmaceutically acceptable thereof; provided that when  is selected from  then at least one of X