Patent ID: 6953785
Filing Date: 2005-10-11
Classification: A61P,C07J

Abstract:
1. A method for inhibiting steroid sulfatase, which comprises administering, to a patient in need thereof, a therapeutically effective amount of an estra-1,3,5(10)-triene derivative which is represented by formula (I): <wherein R 1 and R 2 are the same or different and represent a hydrogen atom or a lower alkyl group, or R 1 and R 2 are combined with N adjacent thereto to form a nitrogen-containing heterocyclic group; R R R R 1) a cyano group, 2) an amino group, 3) CHR 4) COR 5) CSR 6) a substituted or unsubstituted aryl group, 7) a substituted or unsubstituted heterocyclic group, 8) CR 9) CHR 10) NR 11) NR 12) R or a pharmaceutically acceptable salt thereof.