Patent ID: 8067362
Filing Date: 2011-11-29
Classification: A61K,A61P,C07K

Abstract:
1. The insulin derivative having the formula wherein Ins is the parent insulin moiety which via the α-amino group of the N-terminal amino acid residue of the B chain or an ε-amino group of a Lys residue present in the B chain of the insulin moiety is bound to the CO— group in the side chain via an amide bond; W is a bond; m is 0; X is a bond; Y is —(CR Q is a divalent hydrocarbon chain of the formula wherein Q provided that when W is a bond then Q is not a divalent hydrocarbon chain of the formula—(CH Z is selected from the group consisting of: —COOH; —CO-Asp; —CO-Glu; —CO-Gly; —CO-Sar; —CH(COOH) provided that if W is a bond and v