Patent ID: 7271179
Filing Date: 2007-09-18
Classification: A61K,A61P,C07D

Abstract:
1. A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: W and X are each independently oxygen or sulfur; A is nitrogen, CH, C—CN, or C—(C R Q is —C(O)—, —C(O)NR—, —C(O)C(O)—, —CO each R is independently hydrogen or an optionally substituted C R Ar is an optionally substituted ring selected from: provided that said compound is not a compound selected from the group consisting of: 3-Chloro-benzo[b]thiophene-2-carboxylic acid [5-(7-chloro-quinolin-4-ylsulfanyl)-[1,3,4]thiadiazol-2-yl]-amide; N-[5-(7-Chloro-quinolin-4-ylsulfanyl)-[1,3,4]thiadiazol-2-yl]-2-phenoxy-nicotinamide; 5-Methyl-2-phenyl-2H-[1,2,3]triazole-4-carboxylic acid [5-(7-chloro-quinolin-4-ylsulfanyl)-[1,3,4]thiadiazol-2-yl]-amide; Cyclopropanecarboxylic acid [5-(7-chloro-quinolin-4-ylsulfanyl)-[1,3,4]thiadiazol-2-yl]-amide; Thiophene-2-carboxylic acid [5-(7-chloro-quinolin-4-ylsulfanyl)-[1,3,4]thiadiazol-2-yl]-amide; and 4-Hydroxy-2-oxo-2,3-dihydro-quinoline-3-carboxylic acid [5-(7-chloro-quinolin-4-ylsulfanyl)-[1,3,4]thiadiazol-2-yl]-amide.