Patent ID: 8673640
Filing Date: 2014-03-18
Classification: A61L,Y10T

Abstract:
1. A porous scaffold for seeding cells, the porous scaffold comprising: a framework which is a cylinder frame formed of polyethylene and a nylon mesh; a main body located within the framework, the main body being a porous body having a pore size when enables cell seeding; and a porous membrane including pores having a pore size smaller than the size of the cells, wherein an outer peripheral surface of the porous scaffold is covered with the porous membrane, wherein the main body has an entrance for seeding cells which is not covered with the porous membrane, wherein the main body has a multilayer structure comprising layers, and each layer is a porous body comprising at least one selected from the group consisting of a bioabsorbable synthetic polymer, a bioabsorbable natural polymer, a cell growth factor, a cell differentiation control factor, and derivatives thereof, wherein the layers are stacked in an axial direction of the cylinder frame, wherein the layers forming the multilayer structure are different in at least one characteristic selected from the group consisting of composition, porous structure including porosity, size of pores, continuity of pores, and mechanical property, wherein the pore size of the porous body is from 20 to 400 μm, and wherein the pore size of the porous membrane is from 0.45 to 10 μm.