Patent ID: 6281005
Filing Date: 2001-08-28
Classification: A61K,C12N,G01N

Abstract:
A device for compacting nucleic acid complexes to a desired state or size, said device comprising:a support for supporting a batch solution;a dispenser for dispensing an additive solution to the batch solution, the additive solution or the batch solution containing the nucleic acid, and after addition of the additive solution the batch solution contains nucleic acid complexes;a monitor coupled to a submersible probe and a measurement apparatus for monitoring the batch solution to determine whether nucleic acid complexes in the batch solution have reached the desired state or size, wherein said submersible probe is adapted to be placed in the batch solution, said measurement apparatus is connected to said probe for generating measurement data regarding the state or size of the nucleic acid complexes;a processor coupled to said measurement apparatus whereby said processor receives measurement data and calculates whether the nucleic acid complexes have reached a threshold size; anda controller coupled to said processor and said dispenser to control dispensing of the additive solution in response to a signal from said processor.