Patent ID: 8196456
Filing Date: 2012-06-12
Classification: G01N

Abstract:
1. An autosampler for high-performance liquid chromatography, the autosampler comprising: (a) a high-pressure injection valve having at least six ports including first and second load ports for supplying or removing fluid under low pressure, first and second sample loop ports, and first and second high-pressure ports for supplying or removing fluid under high pressure; (b) a sample loop that is connected at one end to one of the sample loop ports and at the other end to the other of the sample loop ports; (c) a high-pressure pump that is connected to one of the high-pressure ports; (d) wherein the at least three grooves of the rotor and the port opening cross sections are constructed and arranged such that: (e) wherein the rotor is forced against the stator by a pressure force that is high enough in order to effect a sealing of the grooves in the rotor surface for pressure fluids higher than 600 bar; and (f) wherein the at least three grooves or the port opening cross sections are provided and constructed in such a manner, and the rotational direction is selected in such a manner that, in a rotation of the rotor from the INJECT position into the LOAD position, the sample loop under high pressure is decompressed in such a manner