Patent ID: 6518284
Filing Date: 2003-02-11
Classification: C07D

Abstract:
A method for treating depression in a human by noradrenaline reuptake blocking, in a human in need of such treatment, by administering 1 to 30 mg/Kg of a compound or pharmaceutically acceptable salts thereof having the formula: wherein R1 and R2 are selected from the group consisting of: aryl radicals, and mono-and poly-substituted aryl radicals substituted with one substitutent selected from the group consisting of: halogen, alkyl, alkoxy, cyano, trifluoromethyl, benzoyl, phenyl, nitro, amino, aminoalkyl, aminoaryl, and carbonylamino; and wherein the compound has a Ki for noradrenaline re-uptake transporters between at least 1 and 40 nmol/l.