Patent ID: 6235516
Filing Date: 2001-05-22
Classification: C12N,C12P,Y10S

Abstract:
A purified biocatalyst isolated from a microorganism selected from the group consisting of Rhodococcus globerulus, Rhodococcus equi and Arthrobacter aurescens, wherein the biocatalyst exhibits amine acylase enzymatic activity without lipase- or esterase-activity, and wherein the biocatalyst stereoselectively hydrolyses a racemic acylamide of formula (1) ##STR12##wherein R.sup.2 is aryl or C.sub.1 -C.sub.4 aryl; or R.sup.1 and R.sup.2 together are forming a 5 to 7 membered ring substituted by or fused to aryl;R.sup.3 is an aliphatic acyl residue; andR.sup.1 and R.sup.3 together are chosen in order to form a compound of formula (1) that is not a derivative of a natural amino acid; wherein each of the residues can be substituted or unsubstituted.