Patent ID: 9066963
Filing Date: 2015-06-30
Classification: A61K,A61P,C12Q,G01N

Abstract:
1. A method of treating breast cancer in a subject in need thereof comprising: (a) providing a biological sample from the subject; (b) assaying the biological sample to determine whether the biological sample is classified as a Her2+ subtype; (c) assaying the biological sample to determine whether the biological sample is classified as a Her-2-E subtype; (d) providing an assessment of the likelihood of effectiveness of a breast cancer treatment comprising an anthracycline in the subject, wherein if the biological sample is classified as both a Her2+ subtype and a Her-2-E subtype, the breast cancer treatment comprising the anthracycline is more likely to be effective in the subject and wherein if the biological sample is classified as a Her-2-E subtype and is classified as not a Her2+ subtype, the breast cancer treatment comprising the anthracycline is less likely to be effective in the subject; and (e) administering a breast cancer treatment comprising anthracycline to the subject subsequent to said assessment if the biological sample is classified as both a Her2+ subtype and a Her-2-E subtype and administering a breast cancer treatment not comprising anthracycline to the subject subsequent to said assessment if the biological sample is classified as a Her-2-E subtype and classified as not a Her2+ subtype, thereby treating breast cancer in the subject.