Patent ID: 6511988
Filing Date: 2003-01-28
Classification: A61K,A61P,C07C,C07D

Abstract:
A compound represented by the formula: wherein:R1 is H, NO2, or NH2; R2 and R3 are the same or different and are H, NO2, or NH2, and when R2 is NH2 then R1 and R3 are H; R4 is (i) â€”CH2CH&boxH;CH2; (ii) â€”CH2Câ‰¡CH; (iii) â€”NHCâ‰¡CH; (iv) â€”NHCH&boxH;CH2; (v) â€”NHCH2CH2N(CH2CH3)2; (vi) â€”NHCH2CH2N(CH3)2; (vii) â€”OH; (viii) (x) â€”(CH2)aN(R5)(R6) wherein a=1 or 2 and R5 and R6 are H or lower alkyl; wherein R7 is H or CF3; wherein X is H, NO2, â€”COOCH3, â€”COOCH2CH3, CH2CH3, or CH3 and R8 is H, CH3, or; wherein X is H, NO2, â€”COOCH3, or CH3 and R8 is H or CH3