Patent ID: 7507574
Filing Date: 2009-03-24
Classification: C07K,C12N

Abstract:
1. A modified Saccharomyces cerevisiae yeast which produces lower levels of ethanol than wild-type yeast under aerobic conditions and glucose concentrations of 2%, and which exhibits a growth rate of at least 30% of the wild-type yeast, wherein said yeast contains a chimeric nucleotide sequence (a chimeric construct) which is stably transformed into the genetic material of the yeast, wherein the construct comprises a sequence having the form A-B wherein A is a first sequence comprising nucleotide bases w to x; B is a second sequence comprising nucleotide bases (x+y) to z; wherein and wherein said chimeric nucleotide sequence is introduced into a yeast cell which is a null strain which exhibits a glucose uptake of less than 2 nmol glucose/min/mg biomass to provide said modified