Patent ID: 8529953
Filing Date: 2013-09-10
Classification: A61K,A61P

Abstract:
1. A method for producing spherical fine particles comprising tamsulosin hydrochloride, the method comprising the steps of: (1) mixing and stirring tamsulosin hydrochloride (a), microcrystalline cellulose (b), and water until a mixture of the component (a) and the component (b) is uniformly impregnated with the water; (2) granulating the mixture obtained in step (1) using an stirring granulator whose peripheral speed is set to be 5.5 to 9.0 m/s; and (3) drying the granules obtained in step (2); wherein spherical fine particles having a particle diameter of from 75 μm to less than 250 μm account for 80 wt % or greater of the entire spherical fine particles obtained.