Patent ID: 9031292
Filing Date: 2015-05-12
Classification: A61B,G01R,G06T

Abstract:
1. A diagnostic method for Parkinson Disease related neurodegenerative disorders, comprising: (a) acquiring a plurality of diffusion weighted images of at least three diffusion weightings and for each diffusion weighting, applying diffusion weighting gradients in three diffusion directions based upon a b-value within the range of 0-4000 sec/mm (b) averaging the images with the diffusion weighting gradients in all diffusion directions for each of the at least three diffusion weightings; and (c) calculating mean kurtosis (MK) value from the at least three diffusion weightings after averaging the at least three diffusion directions to obtain a mean kurtosis (MK) value corresponding to each of the at least three diffusion weightings; and (d) comparing the mean kurtosis values from selected regions of interest (ROI); wherein the b-value is varying from 0 to 4000 sec/mm