Patent ID: 7867712
Filing Date: 2011-01-11
Classification: C12Q

Abstract:
1. A method for identifying a cell exhibiting asymmetric self-renewal comprising measuring the expression level of at least 20 nucleic acid sequences, or measuring the expression level of a mammalian homologue of each of the 20 nucleic acid sequences, wherein the 20 nucleic acid sequences are identified by the following SEQ ID NOs: SEQ ID NO: 231, SEQ ID NO: 298, SEQ ID NO:303, SEQ ID NO: 338, SEQ ID NO: 275, SEQ ID NO: 261, SEQ ID NO: 339, SEQ ID NO: 262, SEQ ID NO: 254, SEQ ID NO: 255, SEQ ID NO: 288, SEQ ID NO: 219, SEQ ID NO: 243, SEQ ID NO: 216, SEQ ID NO: 221, SEQ ID NO: 297, SEQ ID NO: 250, SEQ ID NO: 237, SEQ ID NO: 232, SEQ ID NO: 218; and wherein an increase in expression level relative to isogenic cells not undergoing asymmetric replication of said nucleic acids is indicative of a cell exhibiting asymmetric self-renewal.