Patent ID: 7276519
Filing Date: 2007-10-02
Classification: A61K,A61P,C07D

Abstract:
1. A compound of Formula II wherein: X is —NH—, —NR m is an integer of 0–2; n is an integer of 1–5; q is an integer of 0–5; R R R R R R R R R Y is —C(O)—, —C(O)O—, —OC(O)—, —C(O)NH—, —NHC(O)—, —NHSO Q is NZZ′ wherein Z and Z′ may be the same or different and may be H, alkyl of 1 to 6 carbon atoms, alkenyl of 2–6 carbon atoms, alkynyl of 2–6 carbon atoms, aryl, or heteroaryl, and Z and Z′ taken together with the nitrogen to which they are attached may form a heterocyclic ring which may have an additional heteroatom selected from nitrogen, oxygen, and sulfur, optionally substituted with —R Z″′ and Z″ may be H, alkyl of 1 to 6 carbon atoms, alkenyl of 2–6 carbon atoms, alkynyl of 2–6 carbon atoms, aryl, or heteroaryl Z″ and Z″′ taken together with the nitrogen to which they are attached may form a heterocyclic ring which may contain an additional heteroatom selected from nitrogen, oxygen and sulfur; and J is fluoro, chloro, bromo, or iodo; or a pharmaceutically acceptable salt thereof.