Patent ID: 6075140
Filing Date: 2000-06-13
Classification: C07D

Abstract:
A compound, represented by the following general formula (1) or a salt thereof: ##STR197## wherein R.sup.1 represents a phenyl group, which may have one or more substituent(s) selected from the group consisting of a halogen atom, an alkyl group and an alkoxyl group;R.sup.2 represents an alkyl group, an alkenyl group, or an alkynyl group, in which these alkyl, alkenyl, or alkynyl groups may have one or more substituent(s) selected from the group consisting of a halogen atom, a hydroxyl group, a carboxyl group, an alkoxyl group, an aryloxy group, a phenyl group, an amino group, an alkylamino group, an alkoxycarbonyl group, an aryloxycarbanyl group, an acyl group, an acylamino group and an acyloxy group;R.sup.3 represents a hydrogen atom, a hydroxyl group, an alkoxyl group, a group --O--R.sup.31, an acyloxy group or a group --O--CO--R.sup.31, in which the alkoxyl and acyloxy groups may have one or more substituent(s) selected from the group consisting of a halogen atom, a hydroxyl group, a carboxyl group, an alkoxyl group, an aryloxy group, an amino group, an alkylamino group, an alkoxycarbonyl group, an aryloxycarbonyl group, an acyl group, an acylamino group, an acyloxy group and a heterocyclic group wherein the heterocyclic group may have one or more alkyl group(s) on the constituent atoms of its ring, wherein R.sup.31 represents an alkylamino group, an alkenyl group, an alkynyl group, a cycloalkyl group, an aryl group or a heterocyclic group, in which these alkylamino, alkenyl, alkynyl, cycloalkyl, aryl and heterocyclic groups may have one or more substituent(s) selected from the group consisting of a halogen atom, a hydroxyl group, a carboxyl group, an alkyl group, an alkoxyl group, an aryloxy group, phenyl group, an amino group, an alkylamino group, an aminoalkyl group, an alkylaminoalkyl group, an alkoxycarbonyl group, an aryloxycarbonyl group, an acyl group, an acylamino -group, an acyloxy group and a nitrogen-containing heterocyclic group having a size of three- to eight-membered ring wherein the nitrogen-containing heterocyclic group may have one or more alkyl group(s) on the constituent atoms of its ring;R.sup.4 and R.sup.5 each represents a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, an aryl group or a heterocyclic group, in which these alkyl, alkenyl, alkynyl, aryl and heterocyclic groups may have one or more substituent(s) selected from the group consisting of an alkoxyl group, an amino group, an alkylamino group, an aminoalkyl group, an alkylaminoalkyl group and a nitrogen containing saturated heterocyclic group having a size of five- or six-membered ring represented by the following formula: ##STR198## wherein X represents an oxygen atom, a sulfur atom, CH.sub.2, CH--Y, NH or N--Y, in whichY is an alkyl group; wherein said heterocyclic group may have one or more alkyl group(s) on a carbon atom as a constituent atom of its ring;Z.sup.1 represents a hydrogen atom, a hydroxyl group, a halogen atom or an alkyl group;Z.sup.2 represents a hydrogen atom, a hydroxyl group, a halogen atom or an alkyl group;Z.sup.3 represents a heterocyclic group having a size of a monocyclic five or six membered ring in which the heterocyclic group may have one or more substituent(s) selected from the group consisting of a halogen atom, a hydroxyl group, a carboxyl group, an alkyl group, an alkoxyl group, a phenyl group, an amino group, an alkylamino group, an aminoalkyl group, an alkylaminoalkyl group, an alkoxycarbonyl group, an aryloxycarbonyl group, an acyl group, an acylamino group and an acyloxy group; andZ.sup.4 represents an alkyl group, an aryl group or an alkoxyl group, in which these alkyl, aryl and alkoxyl groups may have one or more substituent(s) selected from the group consisting of a halogen atom, a hydroxyl group, a carboxyl group, an alkyl group, an alkoxyl group, a phenyl group, an amino group, an alkylamino group, an aminoalkyl group, an alkylaminoalkyl group, an alkoxycarbonyl group, an aryloxycarbonyl group, an acyl group, an acylamino group and an acyloxy group;with the proviso that the dotted line of the following moiety: ##STR199## means that the corresponding bonding of the moiety may be a double bond, but R.sup.3 is not a hydroxyl group in that case.