Patent ID: 6716985
Filing Date: 2004-04-06
Classification: A61P,C07D

Abstract:
A process for the preparation of 4-aryl-piperidines of structure (1): in which R is hydrogen or an alkyl, aralkyl, aryl, acyl, alkoxycarbonyl, arylalkoxycarbonyl, aryloxycarbonyl group; and Zâ€² is a 3,4-methylenedioxyphenyl group; which process comprises converting a compound of structure (4c) or (4d): â€ƒin which R is hydrogen or an alkyl, aralkyl, aryl, acyl, alkoxycarbonyl, arylalkoxycarbonyl, aryloxycarbonyl group; and X is hydrogen or from one to four reducible groups; into a compound of structure (1).