Patent ID: 7659087
Filing Date: 2010-02-09
Classification: C12Q,G01N,Y10T

Abstract:
1. A method for scoring the severity of appendicitis of a patient suspected of suffering from appendicitis who is not known to have an interfering condition associated with the presence of elevated MRP-8/14 protein in blood, serum or plasma of said patient, said interfering condition being selected from the group consisting of recent allograft; septicemia; meningitis; pneumonia; tuberculosis; rheumatoid arthritis; gastrointestinal cancer; inflammatory bowel disease; skin cancer, periodontitis, preeclampsia, and AIDS, said method comprising: testing a sample of blood, serum, or plasma from said patient for the quantity of MRP8/14 in said sample; comparing the quantity of MRP8/14 in said sample with the quantity of MRP8/14 in one or more standard samples, wherein the standard sample(s) contain quantity(ies) of MRP8/14 previously correlated with one or more grade scores for appendicitis severity; and assigning to the severity of appendicitis in said patient the grade score of the standard sample that has the quantity of MRP8/14 closest to the quantity of MRP8/14 present in the sample from the patient.