Patent ID: 7816350
Filing Date: 2010-10-19
Classification: A61P,C07D

Abstract:
1. A compound of formula I, or a pharmaceutically acceptable salt thereof, wherein R6 is R6′-X, wherein X is —NH—, —O—, or —S—, and R6′ is an aryl group optionally substituted by one or more substituents selected from chloro, fluoro, hydroxyl, amino, acylamino, acyloxy, carboxyl and amido; or X is —N-(substituted arylalkyl), wherein said substituted arylalkyl is benzylamine substituted by one or more substituents selected from halogen, amino, hydroxy, cyano, nitro, mercapto, alkoxy, alkylamino, dialkylamino, acylamino, carbamoylamino, acyloxy, alkylmercapto, carboxyl, amido, sulfo, sulfamido, sulfamoyl, ureido, guanadino or α-(aminomethyl)-mono-, di- or tri-substituted benzyl alcohol and R6′ is H; R2 is R2′-X, wherein X is —NH—; R2′ is independently Substituted alkyl, acyl, cycloalkyl, substituted cycloalkyl, cycloheteroalkyl, substituted cycloheteroalkyl, cycloalkyl alkyl, aryl, substituted aryl, arylalkyl, heterocyclyl, heteroaryl, substituted heteroaryl, heteroalkyl or heteroarylalkyl, wherein said substituted groups are substituted by one or more substituents selected from halogen, amino, acylamino, acyloxy, hydroxy, mercapto, alkoxy, alkylamino, dialkylamino, alkylmercapto, carboxyl, amido, sulfo, sulfamido, carbamoylamino, nitro and cyano; R9 is alkyl.