Patent ID: 9049848
Filing Date: 2015-06-09
Classification: A01K,C12N,C12Q

Abstract:
1. A method for producing a bovine subject with increased resistance to Enterobacteriaceae infection comprising: a) obtaining samples of genetic material from a bovine donor subjects, the sample comprising a bSynj1 gene; b) probing the samples with an oligonucleotide which selectively hybridizes to a genetic marker sequence for a polymorphism in the bSynj1 gene, said genetic marker linked to Enterobacteriaceae resistance, wherein the polymorphism is a single nucleotide polymorphism occurring at nucleobase number 21 of exon 35, as determined by reference to nucleotide 190 of SEQ ID NO:8; c) identifying samples which contain the genetic marker and selecting those bovine donor subjects for introgression; d) introgressing the polymorphism in the bSynj1 gene into a recipient breed which is non-resistant or exhibits less resistance to Enterobacteriaceae infection.