Patent ID: 7271154
Filing Date: 2007-09-18
Classification: A61K,C07D,C07H

Abstract:
1. A conjugate of the following formula: wherein T is a transportophore, L is a bond or a linker having a molecular weight up to 240 dalton, C is an antibiotic therapeutic agent, and m is 1, 2, 3, 4, 5, 6, 7, or 8, in which the transportophore is covalently bonded to the antibiotic therapeutic agent via the bond or the linker, and the transportophore is an azithromycin derivative and the conjugate has the formula: wherein X=N(R Y=independently a bond or a linker Z=C(═O) R R2=H R R R R R R R R R R R R R R R