Patent ID: 8609122
Filing Date: 2013-12-17
Classification: A61F,A61K,A61L,A61P,B29C,B29L,Y10T

Abstract:
1. A coated structural implant for providing improved integration with natural tissue, the coated structural implant comprising: a structural implant having a surface and being formed with a material suitable for repair of bone, ligament, or tendon; and a bioactive hydrogel matrix layer overlying the surface of the structural implant and immobilized thereon, the hydrogel matrix layer being a solid or semi-solid material at physiological temperature and physiological pH and comprising a polyglycan, a polypeptide, and at least one enhancing agent selected from the group consisting of polar amino acids, divalent cation chelators, and combinations thereof, at least one of the polyglycan and the polypeptide being covalently cross-linked to the surface of the structural implant.