Patent ID: 7105686
Filing Date: 2006-09-12
Classification: C07D

Abstract:
1. A process for the manufacture of compounds represented by the following formula (I) with X 1 , X 2 and X 3 being independently from each other hydrogen or methyl by the catalyzed reaction of a compound a) represented by the following formula (II) with a compound b) selected from the group consisting of phytol, isophytol and (iso)phytol derivatives represented by the following formulae (III) and (IV) with R═C 2-5 -alkanoyloxy, benzoyloxy, mesyloxy, benzenesulfonyloxy or tosyloxy, characterized in that the reaction is carried out in the presence of gadolinium trifluoromethanesulfonate, Gd(OSO 2 CF 3 ) 3 , as the catalyst in a biphasic solvent system.