Patent ID: 6723497
Filing Date: 2004-04-20
Classification: A01N,A61K,Y10T

Abstract:
A process of preparing a dehydrated composition comprising:providing platelets selected from a mammalian species, the platelets being effectively loaded by fluid phase endocytosis with an oligosaccharide therein to preserve biological properties, wherein the loading includes incubating the platelets at a temperature from about 30Â° C. to less than about 40Â° C. with an oligosaccharide solution, the solution having up to about 50 mM oligosaccharide therein, the incubating sufficient to load oligosaccharide inside the platelets in an amount from about 10 mM to about 50 mM; cooling the loaded platelets to below their freezing point; and lyophilizing the cooled platelets.