Patent ID: 8378134
Filing Date: 2013-02-19
Classification: A61K,C07C

Abstract:
1. A contrast enhancement agent comprising an iron chelate having structure I wherein R 1 is independently at each occurrence a hydroxy group, a C 1 -C 3 hydroxyalkyl group, or a C 1 -C 3 alkyl group, and b is 0-4; R 2 -R 7 are independently at each occurrence hydrogen, a C 1 -C 3 hydroxyalkyl group, or a C 1 -C 3 alkyl group, with the proviso that at least one of R 1 -R 7 is a hydroxy group or a C 1 -C 3 hydroxyalkyl group and that when one of R 4 and R 7 is a C 1 -C 3 hydroxyalkyl group at least one of R 1 , R 2 , R 3 , R 5 , or R 6 is also a C 1 -C 3 hydroxyalkyl group; and wherein Q is a charge balancing counterion.