Patent ID: 8029984
Filing Date: 2011-10-04
Classification: C12Q,G01N

Abstract:
1. A method of screening colon tissue for colon cancer, said method comprising: measuring (prospero homeobox protein 1) Prox-1 expression in a biological sample that comprises colon tissue from a human subject; and screening for colon cancer by: (a) detecting the presence of an elevated level of Prox-1 expression in said colon tissue in the biological sample that is statistically significantly greater than the level of Prox-1 expression in healthy colon tissue, wherein said presence of the elevated level of Prox-1 expression is indicative of the presence of colon cancer in the colon tissue of the biological sample; or (b) detecting the absence of an elevated level of Prox-1 expression in said colon tissue in the biological sample that is statistically significantly greater than the level of Prox-1 expression in healthy colon tissue, wherein said absence of the elevated level of Prox-1 expression is indicative of the absence of colon cancer in the colon tissue of the biological sample.