Patent ID: 6989383
Filing Date: 2006-01-24
Classification: A61K,A61P

Abstract:
1. A method for achieving a synergistic therapeutic effect in a mammal in need thereof which comprises administering to said mammal amounts of at least two therapeutic agents selected from a group consisting of: a) a prenyl-protein transferase inhibitor and b) an antineoplastic agent selected from paclitaxel, epothilone A, epothilone B, desoxyepothilone A or desoxyepothilone B, wherein the synergistic therapeutic effect is the treatment of cancers of the brain, breast, colon, genitourinary tract, lymphatic system, pancreas, rectum, stomach, larynx, liver, lung, prostate, stet histiocytic lymphoma lung adenocarcinoma, pancreatic carcinoma, colo-rectal carcinoma, small cell lung cancers or neurological tumor cancer whose growth is inhibited by the administration of the prenyl-protein transferase inhibitor and the antineoplastic agent.