Patent ID: 6334968
Filing Date: 2002-01-01
Classification: A61F,A61K,A61L,C08J

Abstract:
A process for producing a polysaccharide sponge characterized by having: (i) an average pore size in the range between about 10 &mgr;m to about 300 &mgr;m; (ii) an average distance between the pores being the wall thickness of the pores in the range between about 5 &mgr;m to about 270 &mgr;m; and (iii) an E-modului of elasticity being a measure of the rigidity of the sponge in the range of about 50 kPa to about 500 kPa, the process comprising:(a) providing a polysaccharide solution containing about 1% to about 3% w/v polysaccharide in water; (b) optionally diluting said polysaccharide solution with additional water to obtain a final solution having about 0.5% to about 2% w/v polysaccharide, and subjecting said solution of (a) to gelation, to obtain a polysaccharide gel; (c) freezing the gel of (b); and (d) drying the frozen gel of (c) to obtain a polysaccharide sponge.