Patent ID: 6409995
Filing Date: 2002-06-25
Classification: A61K,A61P,A61Q,C07C,C07D

Abstract:
A method of protecting human skin or human hair from UV-radiation comprising treating said hair or skin with an effective amount of a cosmetic or a pharmaceutical formulation containing an amino-substituted hydroxybenzophenone of formula I in which the variables independently of one another have the following meanings:R1 and R2 are hydrogen, C1-C20-alkyl, C2-C10-alkenyl, C3-C10-cycloalkyl, C3-C10-cycloalkenyl, where the substituents R1 and R2 together with the nitrogen atom to which they are bonded can form a 5- or 6-membered ring; R3 and R4 are C1-C20-alkyl, C2-C10-alkenyl, C3-C10-cycloalkyl, C3-C10-cycloalkenyl, C1-C12-alkoxy, C1-C20-alkoxycarbonyl, C1-C12-alkylamino, C1-C12-dialkylamino, aryl, heteroaryl, optionally substituted, substituents which confer solubility in water, chosen from the group consisting of a nitrile group, carboxylate, sulfonate or ammonium radicals; X is hydrogen, COOR5, CONR6R7; R5 to R7 are hydrogen, C1-C20-alkyl, C2-C10-alkenyl, C314 C10-cycloalkyl, C3-C10-cycloalkenyl, â€”(Yâ€”O)oâ€”Z,aryl; Y is â€”(CH2)2â€”, â€”(CH2)3â€”, â€”(CH2)4â€”, â€”CH(CH3)â€”CH2â€”; Z is â€”CH2â€”CH3, â€”CH2â€”CH2â€”CH3, â€”CH2â€”CH2â€”CH2â€”CH3, â€”CH(CH3)â€”CH3; m is from 0 to 3; n is from 0 to 4; is from 1 to 20 as a photostable UV filter.