Patent ID: 8263079
Filing Date: 2012-09-11
Classification: A61K,A61P,C07K

Abstract:
1. An antibody, or fragment thereof, that specifically binds human CSF-1R variant (SEQ ID NO. 15), comprising a CDRH1 comprising the sequence SYGMH (SEQ ID NO:1), a CDRH2 comprising the sequence VIWYDGSNKYYADSVKG (SEQ ID NO:2), a CDRH3 comprising the sequence GDYEVDYGMDV (SEQ ID NO:3), a CDRL1 comprising the sequence RASQGISNALA (SEQ ID NO:4), a CDRL2 comprising the sequence DASSLES (SEQ ID NO:5), and a CDRL3 comprising the sequence QQFNSYPWT (SEQ ID NO:6).