Patent ID: 6420368
Filing Date: 2002-07-16
Classification: A61P,C07D

Abstract:
A compound of the formula I in which:R1 and R2 in each case independently of one another, are H, A or Hal, where at least one of the radicals R1 or R2 is not H, or, optionally R1 and R2 together are alkylene having 3-5 C atoms; R3 and R4 in each case independently of one another are H, A, OA or Hal, or, optionally, R3 and R4 together are alkylene having 3-5 C atoms, â€”Oâ€”CH2â€”CH2â€”, â€”Oâ€”CH2â€”Oâ€” or â€”Oâ€”CH2â€”CH2â€”Oâ€”, X is R5 or R6, which is monosubstituted by R7; R5 is linear or branched alkylene having 1-10 C atoms, in which one or two CH2 groups are optionally replaced by â€”CH&boxH;CHâ€” groups, or is â€”C6H4â€”(CH2)m; R6 is cycloalkylalkylene having 6-12 C atoms; R7 is COOH, COOA, CONH2, CONHA, CON(A)2 or CN; A is alkyl having 1 to 6 C atoms; Hal is F, Cl, Br or I; m is 1 or 2; and n is 1, 2, or 3; or a physiologically acceptable salt thereof.