Patent ID: 9095506
Filing Date: 2015-08-04
Classification: A61K,A61P

Abstract:
1. A biodegradable implant adapted for intraocular use, the implant comprising: (a) about 40 weight % brimonidine free base; (b) about 10 weight % brimonidine tartrate; (c) about 20 weight % first ester end-capped poly (D,L-lactide) polymer having an inherent viscosity of about 0.3 dL/g; (d) about 20 weight % second ester end-capped poly (D,L-lactide) polymer; and (e) about 10 weight % acid end-capped poly (D,L-lactide) polymer having an inherent viscosity of about 0.2 dL/g; and wherein the implant exhibits a substantially linear release of brimonidine over a period of time from about 20 days to about 50 days.