Patent ID: 6369068
Filing Date: 2002-04-09
Classification: C07D

Abstract:
A compound which is:4-(4-Fluorophenyl)-5-[(2-(4-fluoro-2-methylphenyl)amino)pyrimidin-4-yl]-1-(piperidin-4-yl)imidazole; 4-(4-Fluorophenyl)-5-[(2-(5-fluoro-2-methylphenyl)amino)pyrimidin-4-yl]-1-(piperidin-4-yl)imidazole; 4-(4-Fluorophenyl)-5-[(2-(4-fluoro-2,6-dimethylphenyl)amino)pyrimidin-4-yl]-1-(piperidin-4-yl)imidazole; 4-(4-Fluorophenyl)-5-[(2-(4-fluoro-2-chlorophenyl)amino)pyrimidin-4-yl]-1-(piperidin-4-yl)imidazole; trans 4-(4-Fluorophenyl)-5-[(2-(4-fluoro-2-methylphenyl)amino)pyrimidin-4-yl]-1-(4-hydroxycyclohexyl)imidazole; trans 4-(4-Fluorophenyl)-5-[(2-(4-fluorophenyl)amino)pyrimidin-4-yl]-1-(4-hydroxycyclohexyl)imidazole; trans 4-(4-Fluorophenyl)-5-[(2-(3-fluoro-2-methylphenyl)amino)pyrimidin-4-yl]-1-(4-hydroxycyclohexyl)imidazole; trans 4-(4-Fluorophenyl)-5-[(2-(5-fluoro-2-methylphenyl)amino)pyrimidin-4-yl]-1-(4-hydroxycyclohexyl)imidazole; trans 4-(4-Fluorophenyl)-5-[(2-(4-fluoro-2-chlorophenyl)amino)pyrimidin-4-yl]-1-(4-hydroxycyclohexyl)imidazole; cis 4-(4-Fluorophenyl)-5-[(2-(4-fluoro-2-methylphenyl)amino)pyrimidin-4-yl]-1-(4-hydroxycyclohexyl)imidazole; cis 4-(4-Fluorophenyl)-5-[(2-(4-fluorophenyl)amino)pyrimidin-4-yl]-1-(4-hydroxycyclohexyl)imidazole; cis 4-(4-Fluorophenyl)-5-[(2-(3-fluoro-2-methylphenyl)amino)pyrimidin-4-yl]-1-(4-hydroxycyclohexyl)imidazole; cis 4-(4-Fluorophenyl)-5-[(2-(5-fluoro-2-methylphenyl)amino)pyrimidin-4-yl]-1-(4-hydroxycyclohexyl)imidazole; cis 4-(4-Fluorophenyl)-5-[(2-(4-fluoro-2-chlorophenyl)amino)pyrimidin-4-yl]-1-(4-hydroxycyclohexyl)imidazole; trans 4-(4-Fluorophenyl)-5-[(2-(4-fluoro-2-methylphenyl)amino)pyrimidin-4-yl]-1-(4-hydroxy-4-methylcyclohexyl)imidazole; trans 4-(4-Fluorophenyl)-5-[(2-(4-fluorophenyl)amino)pyrimidin-4-yl]-1-(4-hydroxy-4-methylcyclohexyl)imidazole; trans 4-(4-Fluorophenyl)-5-[(2-(3-fluoro-2-methylphenyl)amino)pyrimidin-4-yl]-1-(4-hydroxy-4-methylcyclohexyl)imidazole; trans 4-(4-Fluorophenyl)-5-[(2-(5-fluoro-2-methylphenyl)amino)pyrimidin-4-yl]-1-(4-hydroxy-4-methylcyclohexyl)imidazole; trans 4-(4-Fluorophenyl)-5-[(2-(4-fluoro-2-chlorophenyl)amino)pyrimidin-4-yl]-1(4-hydroxy-4-methylcyclohexyl)imidazole; cis 4-(4-Fluorophenyl)-5-[(2-(4-fluoro-2-methylphenyl)amino)pyrimidin-4-yl]-1-(4-hydroxy-4-methylcyclohexyl)imidazole; cis 4-(4-Fluorophenyl)-5-[(2-(4-fluorophenyl)amino)pyrimidin-4-yl]-1-(4-hydroxy-4-methylcyclohexyl)imidazole; cis 4-(4-Fluorophenyl)-5-[(2-(3-fluoro-2-methylphenyl)amino)pyrimidin-4-yl]-1-(4-hydroxy-4-methylcyclohexyl)imidazole; cis 4-(4-Fluorophenyl)-5-[(2-(5-fluoro-2-methylphenyl)amino)pyrimidin-4-yl]-1-(4-hydroxy-4-methylcyclohexyl)imidazole; cis 4-(4-Fluorophenyl)-5-[(2-(4-fluoro-2-chlorophenyl)amino)pyrimidin-4-yl]-1-(4-hydroxy-4-methylcyclohexyl)imidazole; or a pharmaceutically acceptable salt thereof.