Patent ID: 6303110
Filing Date: 2001-10-16
Classification: A61K,A61Q

Abstract:
A composition for the first stage of a process for the permanent reshaping of keratin fibers comprising:i) an effective amount of at least one ceramide compound of formula (II) below: ##STR2##wherein:R.sub.1 is chosen from:a saturated or unsaturated, linear or branched C.sub.1 -C.sub.50 hydrocarbon radical, it being possible for said radical to be substituted with at least one hydroxyl group which may be esterified with an acid R.sub.7 COOH, wherein R.sub.7 is chosen from a saturated or unsaturated, linear or branced, optionally mono- or polyhydroxylated C.sub.1 -C.sub.35 hydrocarbon radical, it being possible for the hydroxyl(s) of the radical R.sub.7 to be esterified with a saturated or unsaturated, linear or branched, optionally mono- or polyhydroxylated C.sub.1 -C.sub.35 fatty acid.a radical R""--(NR--CO)--R' wherein R is chosen from a hydrogen atom and a mono- or polyhydroxylated C.sub.1 -C.sub.20 hydrocarbon radical, and R' and R"" are independently chosen from hydrocarbon radicals, wherein the sum of the carbon atoms of R' and R"" ranges from 9 to 30, and further wherein R' is a divalent radical, anda radical R.sub.8 --O--CO--(CH.sub.2).sub.p wherein R.sub.8 is chosen from C.sub.1 -C.sub.20 hydrocarbon radicals, and p is an integer ranging from 1 to 12;R.sub.2 is selected from a hydrogen atom, a saccharide radical, a sulphate or phosphate residue, a phosphorylethylamine radical, and a phosphorylethylammonium radical;R.sub.3 is chosen from a hydrogen atom and a saturated or unsaturated, hydroxylated or non-hydroxylated C.sub.1 -C.sub.33 hydrocarbon radical, it being possible for the hydroxyl(s) to be etherified with a (glycosyl).sub.n, (galactosyl).sub.m, sulphogalactosyl, phosphorylethylamine or phosphorylethylammonium radical, wherein n is an integer ranging from 1 to 4 and m is an integer ranging from 1 to 8, it being further possible for the hydroxyl(s) to be esterified with an inorganic acid or an acid R.sub.7 COOH, wherein R.sub.7 is chosen form a saturated or unsaturated, linear or branched, optionally mono- or polyhydroxylated C.sub.1 -C.sub.35 hydrocarbon radical, it being possible for the hydroxyl(s) of the radical R.sub.7 to be esterified with a saturated or unsaturated, linear or branched, optionally mono- or polyhydroxylated C.sub.1 -C.sub.35 fatty acid, and it being further possible for said saturated or unsaturated, hydroxylated or non-hydroxylated C.sub.1 -C.sub.33 hydrocarbon radical to be substituted with at least one C.sub.1 -C.sub.14 alkyl radical;R.sub.4 is chosen from a hydrogen atom, a methyl or ethyl radical, a saturated or unsaturated, linear or branced, optionally hydroxylated C.sub.3 -C.sub.50 hydrocarbon radical, and a radical --CH.sub.2 --CHOH--CH.sub.2 --O--R.sub.6, wherein R.sub.6 is chosen from a C.sub.10 -C.sub.26 hydrocarbon radical and a radical R.sub.8 --O--CO--(CH.sub.2).sub.p, wherein R.sub.8 is chosen from C.sub.1 -C.sub.20 hydrocarbon radical, and wherein p is an integer ranging from 1 to 12;R.sub.5 is chosen from a hydrogen atom and a saturated or unsaturated, linear or branched, optionally mono- or polyhydroxylated C.sub.1 -C.sub.30 hydrocarbon radical, it being possible for the hydroxyl(s) to be etherified with a (glycosyl).sub.n, (galactosyl).sub.m, sulphogalactosyl, phosphorylethylamine or phosphorylethylammonium radical, wherein n is an integer ranging from 1 to 4 and m is an integer ranging from 1 to 8;with the proviso that when R.sub.3 and R.sub.5 are both hydrogen or when R.sub.3 is hydrogen and R.sub.5 is methyl, then R.sub.4 is not a hydrogen atom or a methyl or ethyl radical, andii) an effective amount of at least one reducing agent of formula (I) below:HS--CH.sub.2 --R (I)wherein R is chosen from a carboxyl radical, a C.sub.1 -C.sub.4 aminoalkyl radical, a carboxy(C.sub.1 -C.sub.4)alkyl radical optionally substituted with an amino group, a C.sub.1 -C.sub.4 ureidoalkyl radical, a (C.sub.1 -C.sub.4)acylamino(C.sub.1 -C.sub.4)alkyl radical, an amino(C.sub.1 -C.sub.4)acylamino(C.sub.1 -C.sub.4)alkyl radical, a (C.sub.1 -C.sub.4)-alkoxycarbonyl radical, a monohydroxy(C.sub.1 -C.sub.4)-alkoxycarbonyl radical, a dihydroxy(C.sub.2 -C.sub.4)alkoxycarbonyl radical, a (C.sub.1 -C.sub.4)alkoxycarbonyl(C.sub.1 -C.sub.4)alkyl radical optionally substituted with an amino group, a monohydroxy(C.sub.1 -C.sub.4)alkoxycarbonyl-(C.sub.1 -C.sub.4)alkyl radical optionally substituted with an amino group, and dihydroxy(C.sub.2 -C.sub.4)alkyxycarbonyl(C.sub.1 -C.sub.4)alkyl radical optionally substituted with an amino group, wherein said composition is free of vesicles containing a reducing agent.