Patent ID: 8034381
Filing Date: 2011-10-11
Classification: A61K

Abstract:
1. Method for the production of ultra-fine suspensions comprising: dissolving a substance which is a solid at 20° C. in a solvent to form a solution; very rapidly and substantially removing the solvent from said solution to obtain a powder comprising particles of which have an average particle size in the range of 1 to 50 μm (according to laser diffractometry); dispersing the powder in a dispersing medium to obtain a suspension; and further processing the suspension by applying medium to high mixing forces to form a suspension comprising solid particles of which having an average particle size (according to photon correlation spectroscopy (PCS)) below 1 μm; wherein the polydispersity index of the resulting particle is decreased and wherein the substance is a medical drug, cosmetically active agent, an additive for food, a dye or a pigment.