Patent ID: 7132527
Filing Date: 2006-11-07
Classification: C07K,C12N,C12P

Abstract:
1. An isolated polynucleotide comprising the nucleic acid sequence of a Streptomyces lividins glucose isomerase promoter, as set forth in SEQ ID NO. 9, or a variant of SEQ ID NO. 9, said variant comprising SEQ ID NO. 9 with only one mutation selected from the group consisting of: a) a substitution at base 123 with T; b) a substitution at base 123 with G; c) a substitution at base 123 with C; d) a substitution at base 121 with C; e) a substitution at base 118 with A; and f) a substitution at base 118 with C, wherein said variant exhibits reduced promoter activity relative to SEQ ID NO. 9.