Patent ID: 6197970
Filing Date: 2001-03-06
Classification: C07D

Abstract:
A process for producing a 2-hydroxybenzamide derivative represented by formula (2): ##STR7##wherein R.sup.2, R.sup.3, and R.sup.4 are the same or different and each independently represents a hydrogen atom, a hydroxy group, a lower alkyl group, a lower alkoxy group, a lower alkylsulfonyl group, a halogen atom, a nitro group, a cyano group, a mono- or di-lower alkylamino group, or a mono- or di-lower alkylcarbonylamino group, or R.sup.2 and R.sup.3 may join to each other to form a methylenedioxy group; R.sup.5 represents a hydrogen atom, a lower alkyl group, a lower alkylsulfonyl group, a halogen atom, a nitro group, a cyano group, a mono- or di-lower alkylamino group, or a mono- or di-lower alkylcarbonylamino group; and R.sup.6 represents a hydroxy group, a lower alkyl group, or a lower alkoxy group; which comprises reacting a 2-substituted benzamide compound represented by formula (1): ##STR8##wherein R.sup.1 represents a substituted or unsubstituted lower alkyl group, a substituted or unsubstituted allyl group, or a substituted or unsubstituted tetrahydropyranyl group; and R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 have the same meanings as described above; with a secondary amine or a tertiary amine.