Patent ID: 7364878
Filing Date: 2008-04-29
Classification: C07K,C12N

Abstract:
1. A cell comprising a first polypeptide expression unit and a second polypeptide expression unit, said first and said second polypeptide expression units each encoding at least one polypeptide of interest, wherein said first and second polypeptide expression units each comprise at least one sequence having the capacity to at least in part block chromatin-associated repression, wherein said sequence having the capacity to at least in part block chromatin-associated repression for the first polypeptide expression unit comprises SEQ ID NO: 7 or a fragment thereof able to, at least in part, block chromatin-associated repression, and wherein said sequence having the capacity to at least in part block chromatin-associated repression for the second polypeptide expression unit is selected from the group consisting of: any one of SEQ ID NO: 1 through SEQ ID NO: 65 and fragments thereof; wherein at least one of said first and said second polypeptide expression units comprises a heterologous promoter.