Patent ID: 8211944
Filing Date: 2012-07-03
Classification: A61K,A61P

Abstract:
1. A method for treating sarcopenia of an elderly subject, said method comprising: administering via oral route to the elderly subject a therapeutically effective amount of a composition comprising, as active ingredients, the following: (i) the branched chain amino acids leucine, isoleucine, and valine, and/or salts thereof; (ii) lysine and threonine, or salts thereof; and (iii) other essential amino acids selected from: histidine, methionine, phenylalanine, and tryptophan, or salts thereof, wherein the amount in moles of threonine is smaller than the individual amounts of lysine and of said branched amino acids, or salts thereof, but greater than the sum of the individual amounts in moles of said other essential amino acids, or salts thereof; and the amount in moles of lysine is smaller than the individual amounts of said branched amino acids, or salts thereof, but greater than the sum of the individual amounts in moles of said other essential amino acids, or salts thereof, wherein isoleucine, valine, threonine, and lysine are present in the following molar ratios to leucine: isoleucine/leucine having a molar ratio from 0.2 to 0.7; valine/leucine having a molar ratio from 0.2 to 0.7; threonine/leucine having a molar ratio from 0.15 to 0.50; and lysine/leucine having a molar ratio from 0.15 to 0.60.