Patent ID: 6309351
Filing Date: 2001-10-30
Classification: A61B

Abstract:
A method for monitoring a physiologic analyte in a subject, comprising steps of:(a) collecting the analyte in a collection reservoir, wherein (i) said collection reservoir is in contact with the subject such that the analyte can move from the subject into said collection reservoir, and (ii) the collection reservoir is in operative contact with a detector;(b) contacting the analyte in the collection reservoir with an enzyme that reacts with the analyte to produce a detectable chemical species, wherein the reaction of the analyte and the enzyme further results in conversion of the analyte to a reaction product that is not detected by the detector;(c) using the detector to detect the detectable chemical species in the collection reservoir, and once the detectable chemical species has been detected, rendering the detectable chemical species undetectable by the detector; and(d) repeating steps (a), (b) and (c).