Patent ID: 8936793
Filing Date: 2015-01-20
Classification: A61K,A61P,C07H

Abstract:
1. A synthetic lipid consisting of an archaeal core lipid and at least one polar carbohydrate head group wherein said archaeal core lipid is archaeol (2,3-di-O-diphytanyl-sn-glycerol) or caldarchaeol (2,2′,3,3′-tetra-O-dibiphytanyl-sn-diglycerol) and said polar carbohydrate head group is selected from the group consisting of: β-D-Glc-(1,6)-α-D-Glc-; α-D-Glc-(1,6)-β-D-Glc-; β-D-Glc-(1,4)-β-D-Glc-; α-D-Glc-(1,4)-β-D-Glc-; β-D-Gal-(1,4)-β-D-Glc-; α-D-Gal-(1,6)-β-D-Glc-; β-D-Glc-(1,6)-β-D-Glc-(1,6)-β-D-Glc-; α-D-Glc-(1,4)-α-D-Glc-(1,4)-β-D-Glc-; α-D-Man-(1,2)-α-D-Man-(1,2)-α-D-Man-; and α-D-Man-(1,2)-α-D-Man-(1,2)-α-D-Man-(1,2)-α-D-Man-, and wherein said polar carbohydrate head group is linked to the archaeal core lipid by covalent bonding to at least one free hydroxyl group on the archaeal core lipid.