Patent ID: 9127044
Filing Date: 2015-09-08
Classification: A61K,A61P,C07K

Abstract:
1. A method of treating a subject suffering from psoriasis comprising administering to said subject a therapeutically effective amount of a cyclic depsipeptide, having the structure of formula (I): wherein an ester bond is formed between the carboxy group of A wherein X and A and wherein X is H or an amino group modifying moiety selected from an aryl carbonyl residue or from an acyl residue, A A A A wherein Ahp, 3-amino-piperidine-2-one, dehydro-AHP, Ahp-I, and Ahp-II, are as defined below, and wherein the points of fusion (with A wherein X is O or a bond, and R is an organic moiety or is a radical selected from the group consisting of hydrogen, (C A A A or a pharmaceutically acceptable salt thereof.