Patent ID: 6927227
Filing Date: 2005-08-09
Classification: A61K,A61P,C07D

Abstract:
1. A compound having the structure its stereoisomers, a pharmaceutically acceptable salt or prodrug ester thereof, wherein R R R X is a bond or a linker group selected from (CH Z is CO  or its tautomer; and  the group  represents a heteroaryl group of the formula where Y is NR which may further be optionally substituted with one or two groups, which may be the same or different and are independently selected from alkyl, alkenyl, hydroxyalkyl, keto, carboxyalkyl, carboxy, cycloalkyl, alkoxy, forrnyl, alkanoyl, alkoxyalkyl or alkoxycarbonyl, with the provisos that (1) n≈o when Z is CO (2) when  then X—Z may not be O-lower alkylene-CO