Patent ID: 6500409
Filing Date: 2002-12-31
Classification: A61K,A61P,A61Q

Abstract:
An oral antigingivitis composition comprising an orally acceptable vehicle of a combination of a noncationic halogenated hydroxydiphenyl ether and an extract of Magnolia Cortex, the bark of Magnolia officinalis containing hydroxybiphenol compound selected from the group consisting of magnolol, honokiol, and mixtures thereof whereby plaque bacteria growth inhibition from the combination of the halogenated hydroxydiphenyl ether and hydroxybiphenol compounds exceeds the additive effect from the compounds if employed alone, the effective amount of the hydroxydiphenyl ether being in the range of about 0.003 to about 2% by weight and that of the Magnolia Extract being in the range of 0.001 to abut 10% by weight, and containing 2 to 50% by weight magnolol and 1 to 20% by weight honokiol.