Patent ID: 7642276
Filing Date: 2010-01-05
Classification: A61P,C07D

Abstract:
1. A compound of formula (I): wherein A is a fused 5-membered heteroaryl ring selected from which ring is optionally substituted by up to two substituents independently selected from C 1-6 alkyl, —(CH 2 ) m —C 3-7 cycloalkyl, halogen, cyano, trifluoromethyl, —(CH 2 ) m OR 3 , —(CH 2 ) m CO 2 R 3 , —(CH 2 ) m NR 3 R 4 , —(CH 2 ) m CONR 3 R 4 , —(CH 2 ) m NHCOR 3 , —(CH 2 ) m SO 2 NR 3 R 4 , —(CH 2 ) m NHSO 2 R 3 , —(CH 2 ) m SO 2 (CH 2 ) n R 5 , a 5- or 6-membered heterocyclyl ring containing nitrogen optionally substituted by C 1-2 alkyl or —(CH 2 ) m CO 2 R 3 , and a 5-membered heteroaryl ring optionally substituted by C 1-2 alkyl; R R R R R R R R R R R R R R R R R R R X and Y are each independently selected from hydrogen, methyl and halogen; m is selected from 0, 1, 2 and 3; n is selected from 0, 1, 2 and 3; q is selected from 0, 1 and 2; r is selected from 0 and 1; and s is selected from 0, 1, 2 and 3.