Patent ID: 9145426
Filing Date: 2015-09-29
Classification: A61K,A61P,C07D

Abstract:
1. A compound, or a stereoisomer of said compound, or a pharmaceutically acceptable salt of said compound or said stereoisomer, said compound having the structural Formula (I): or its tautomeric form, Formula (I′): wherein: one of W and Z is C(R ring A is selected from the group consisting of monocyclic aryl, monocyclic heteroaryl, monocyclic cycloalkyl, monocyclic cycloalkenyl, monocyclic heterocycloalkyl, monocyclic heterocycloalkenyl, and a multicyclic group; each ring B (when present) is independently selected from the group consisting of monocyclic aryl, monocyclic heteroaryl, monocyclic cycloalkyl, monocyclic cycloalkenyl, monocyclic heterocycloalkyl, monocyclic heterocycloalkenyl, and a multicyclic group; m, n, and p are each independently selected integers, wherein: m is 0 or more; n is 0 or 1; and p is 0 or more, wherein the maximum value of m is the maximum number of available substitutable hydrogen atoms on ring A, and wherein the maximum value of p is the maximum number of available substitutable hydrogen atoms on ring B; -L R each R wherein said alkyl, said haloalkyl, said heteroalkyl, said alkenyl, said alkynyl, said aryl, said -alkyl-aryl, said monocyclic heteroaryl, said alkyl-(monocyclic heteroaryl), said monocyclic cycloalkyl, said -alkyl-(monocyclic cycloalkyl), and said monocyclic heterocycloalkyl, said multcyclic group, and said -alkyl-(multicyclic group) of R each R wherein said alkyl, haloalkyl, heteroalkyl, alkenyl, alkynyl, cycloalkyl, -alkyl-cycloalkyl, aryl, -alkyl-aryl, heteroaryl, -alkyl-heteroaryl, and heterocycloalkyl of R each R wherein said alkyl, haloalkyl, heteroalkyl, alkenyl, alkynyl, cycloalkyl, -alkyl-cycloalkyl, aryl, -alkyl-aryl, heteroaryl, -alkyl-heteroaryl, and heterocycloalkyl of R R each R each R wherein each said aryl, -alkyl-aryl, heteroaryl, and -alkyl-heteroaryl of R each R each R wherein each said multicyclic group (when present) is selected from the group consisting of bicyclic aryl, bicyclic heteroaryl, bicyclic cycloalkyl, bicyclic cycloalkenyl, bicyclic heterocycloalkyl, bicyclic heterocycloalkenyl, tricyclic aryl, tricyclic heteroaryl, tricyclic cycloalkyl, tricyclic cycloalkenyl, tricyclic heterocycloalkyl, and tricyclic heterocycloalkenyl.