Patent ID: 6710047
Filing Date: 2004-03-23
Classification: A61P,C07D

Abstract:
A compound of the formula I whereinr is 0 to 2; n is 0; m is 0 to 1; R1 and R2 (i) are lower alkyl or (ii) together form a bridge in subformula (I*) â€ƒthe binding being achieved via the two terminal carbon atoms, or (iii) together form a bridge in subformula I** â€ƒwherein one or two of the ring members T1, T2, T3 and T4 are nitrogen, and the others are in each case CH, and the binding is achieved via T1 and T4 A, B, D, and E are, independently of one another, N or CH, with the stipulation that not more than 2 of these radicals are N, and with further stipulation that when R1 and R2 together form a bridge in subformula (I*) or a bridge in subformula (I**), A, B, D and E are not CH in each case; G is lower alkylene; Q is methyl, which is bound to A, to D, or to A and D; R is H or lower alkyl; X is imino; Y is phenyl, which is unsubstituted or substituted by one or two substituents independently of one another from the group comprising amino, lower alkanoylamino, halogen, lower alkyl, halogen-lower alkyl, halogen-lower alkyl, hydroxy, lower alkoxy, phenyl-lower alkoxy and cyano; or is pyridyl; Z is amino; N-lower alkylamino; hydroxy-lower alkylamino; phenyl-lower alkylamino; N,N-di-lower alkylamino; n-phenyl-lower alkyl-N-lower alkylamino; N,N-di-lower alkylphenylamino; lower alkanoylamino; a substituent from the group comprising benzoylamino or phenyl-lower alkoxycarbonylamino, wherein in phenyl radical in each case is unsubstituted or substituted by nitro, amino, halogen, N-lower alkylamino, N,N-di-lower alkylamino, hydroxy, cyano, carboxy, lower alkyoxycarbonyl, lower alkanoyl or carbamoyl; or is halogen; and the bonds characterized by a wavy line are in each case a double bond or in each case a single bond; or a salt thereof.