Patent ID: 7879966
Filing Date: 2011-02-01
Classification: A61K,A61P

Abstract:
1. A pharmaceutical composition comprising: a pH-sensitive polymer or a conjugate of a pH-sensitive polymer, optionally, at least one pharmacologically active ingredient, and, optionally, at least one pharmaceutically acceptable carrier or excipient; wherein said pH-sensitive polymer comprises: 20 to 65% by weight of methacrylic acid units, and 80 to 35% by weight of units of C wherein said pH-sensitive polymer has a molecular weight in the range from 1,000 to 50,000 g/mol, and brings about at least 60% haemolysis at pH 5.5, and less than 5% haemolysis at pH 7.4, at a concentration of 150 μg/ml in a cytotoxicity test with human red blood cells.