Patent ID: 6939033
Filing Date: 2005-09-06
Classification: A61K,B01F,B01J,Y10T

Abstract:
1. A method of preparing microparticles, comprising: combining a first phase, comprising an active agent, a polymer, and a solvent, and a second phase in a first static mixer to form an emulsion, the emulsion forming an outflow of the first static mixer; combining the outflow of the first static mixer and a first portion of a starting volume of an extraction liquid for extracting solvent from the emulsion in a manifold, wherein the manifold comprises a plurality of individual static mixers configured to form a plurality of parallel flow streams, each of the plurality of parallel flow streams comprising at least one of the plurality of individual static mixers; and combining an outflow of the manifold with a second portion of the extraction liquid to extract solvent from the emulsion.