Patent ID: 6555538
Filing Date: 2003-04-29
Classification: C07D

Abstract:
A compound of the formula or a pharmaceutically acceptable salt thereof; whereina is 1, 2, 3 or 4; X is N; R1 and R2 are each independently selected from hydrogen, (C1-C6)alkyl, cyano, amino, (C1-C6)alkylamino, ((C1-C6)alkyl)2amino, (C3-C7)cycloalkyl, (C6-C10)aryl; R3 and R4 are each independently selected from hydrogen, halo, (C1-C6)alkyl, (C1-C6)alkoxy, cyano, hydroxy, amino, (C1-C6)alkylamino, ((C1-C6)alkyl)2amino, (C3-C7)cycloalkyl, (C3-C7)cycloalkoxy, (C6-C10)aryl; or R1 and R2 may be taken together with the carbons to which they are attached to form a compound of formula II whereina, X, R3 and R4 are as defined above; X is CH or N; b is 1, 2, 3 or 4; and R5 is hydrogen, halo, (C1-C6)alkyl, (C1-C6)alkoxy, cyano, hydroxy, amino, (C1-C6)alkylamino, ((C1-C6)alkyl)2amino, (C3-C7)cycloalkyl, (C3-C7)cycloalkoxy, (C6-C10)aryl.