Patent ID: 7232679
Filing Date: 2007-06-19
Classification: C12N,C12P,C12R,C12Y

Abstract:
1. An isolated polypeptide comprising an amino acid sequence selected from the group consisting of: SEQ ID NO: 47; an amino acid sequence of a fragment of SEQ ID NO: 47 having hydroxymethylglutaryl-CoA synthase (HMG-CoA synthase) activity; an amino acid sequence of a polypeptide having HMG-CoA synthase activity, which is encoded by a polynucleotide that hybridizes to the nucleic acid sequence of SEQ ID NO: 46 under the following conditions: hybridization in 40% formamide, 1M NaCl, 1% sodium dodecyl sulfate (SDS) at 37° C., followed by at least one wash in 0.2×SSC at 60° C. for 20 minutes; and an amino acid sequence of a polypeptide having HMG-CoA synthase activity, which is at least 95% identical to SEQ ID NO: 47.