Patent ID: 8668930
Filing Date: 2014-03-11
Classification: A61K,A61Q

Abstract:
1. A system for sustained release delivery of at least one active ingredient from a film coating, the system comprising stable, homogeneously-dispersed, porous polymeric or co-polymeric beads crosslinked with a polyethylenically unsaturated monomer and at least one porogen, which porogen may be retained during purification, the beads comprising a continuous network of interconnecting pores comprising a population of (i) macropores; (ii) mesopores, and (iii) micropores of ≦20 Å diameter, having porosity when applied as a liquid or gel film coating from which at least one active ingredient, uniformly and non-covalently contained therein, is continuously transported outward by internal flow, wherein the micropores control the sustained release from the pore network to a coated surface for at least 24 hours from film application, and wherein the network of pores is non-collapsible upon delivery of the active ingredient.