Patent ID: 6099832
Filing Date: 2000-08-08
Classification: A61K,A61P,C12N

Abstract:
Isolated cells, said cells comprising at least one of the following cell types:adult cardiomyocytes;pediatric cardiomyocytes;adult fibroblasts;fetal fibroblasts;adult smooth muscle cells;fetal smooth muscle cells;endothelial cells; orskeletal myoblasts,wherein said cells survive in myocardial scar tissue after transplantation into said myocardial scar tissue, and wherein said cells improve cardiac function, relative to cardiac function of a heart having similar myocardial scar tissue that is not transplanted with said cells, wherein cardiac function is assessed by at least one of the criteria selected from the group consisting of: area occupied by said scar tissue; vascularization of said scar tissue; blood flow to said scar tissue; developed pressure; systolic pressure; end diastolic pressure; and .DELTA.Pressure/.DELTA.time.