Patent ID: 8084253
Filing Date: 2011-12-27
Classification: A61K,A61P,C12N

Abstract:
1. A non-naturally occurring antigen-presenting cell derived from Drosophila melanogaster comprising cell surface MHC class I and at least one antigenic peptide from human IgE wherein the antigen presenting cell is capable of activating CD8+ cells wherein at least one human IgE antigenic peptide is selected from the group consisting of: TQSPSVFPL (SEQ ID NO: 64), SLNGTTMTL (SEQ ID NO: 50), TMTLPATTL (SEQ ID NO: 69), TLPATTLTL (SEQ ID NO:67), TLSGHYATI (SEQ ID NO:68), WVDNKTFSV (SEQ ID NO: 51), WLSDRTYTC (SEQ ID NO: 52), ALMRSTTKT (SEQ ID NO: 65), NFMPEDISV (SEQ ID NO: 79), YATISLLTV (SEQ ID NO: 58), TLTVTSTLPV (SEQ ID NO:56), SVQWLHNEV (SEQ ID NO: 76), QWLHNEVQL (SEQ ID NO: 80), TLACLIQNFM (SEQ ID NO: 59), and QVMDVDLSTA (SEQ ID NO: 60).