Patent ID: 9121855
Filing Date: 2015-09-01
Classification: C07K,C12N,G01N

Abstract:
1. A method for detecting the presence, or measuring the concentration, of an anti-HIV-1 antibody in a biological sample of a human, wherein said method comprises conducting an immunoassay comprising the steps of: (a) contacting said biological sample with at least one epitope that is recognized by said anti-HIV-1 antibody, wherein said contacting being under conditions sufficient to permit said anti-HIV-1 antibody if present in said sample to bind to said epitope and form an epitope-anti-HIV-1 antibody complex; (b) contacting said formed epitope-anti-HIV-1 antibody complex with an anti-HIV-1 antibody binding molecule, said contacting being under conditions sufficient to permit said anti-HIV-1antibody binding molecule to bind to anti-HIV-1 antibody of said formed epitope-anti-HIV-1antibody complex and form an extended complex; and (c) determining the presence or concentration of said anti-HIV-1 antibody in said biological sample by determining the presence or concentration of said formed extended complex; said epitope being present on a peptide consisting essentially of SEQ ID No. 55.