Patent ID: 7560253
Filing Date: 2009-07-14
Classification: A61K,A61P,C07K

Abstract:
1. A method for detecting the level of expression of a hemopoietic linkage switch-5 (HLS-5) polynucleotide in a biological sample from a suspected or known cancer patient comprising: (a) providing a biological sample from the patient comprising a nucleic acid; (b) contacting, under stringent hybridizing conditions, the biological sample with a polynucleotide probe or primer capable of hybridizing to an HLS-5 polynucleotide selected from the group consisting of: (c) determining a total amount of duplex formed in the sample between the probe or primer and HLS-5 polynucleotide selected from the group consisting of (b)(i), (b)(ii), and (b)(iii); and (d) comparing the total amount of duplex in step (c) to a control or standard comprising a known amount of an HLS-5 polynucleotide found in a comparable biological sample taken from a non-cancer patient.