Patent ID: 6605448
Filing Date: 2003-08-12
Classification: A61K,C07K,C12N,C12Q,G01N

Abstract:
A population of recombinant vectors comprising:a population of filamentous bacteriophage wherein each filamentous bacteriophage comprises a recombinant structural gene wherein each structural gene comprises an insert consisting of one member of an oligonucleotide population and wherein the population of filamentous bacteriophage comprise a plurality of different members of the oligonucleotide population, said oligonucleotide population comprising oligonucleotides comprising a coding region consisting of a length from about 4 to about 12 nucleotide triplets, said oligonucleotide population encoding a plurality of corresponding random peptide sequences from about 4 to about 12 L-amino acid residues, and wherein said recombinant structural genes are expressed upon transfer of said recombinant vectors into Escherichia coli host cells, and wherein expression of the recombinant structural genes yields polypeptides, each poly peptide comprising one of said plurality of corresponding random peptide sequences.