Patent ID: 6642381
Filing Date: 2003-11-04
Classification: A61P,C07D

Abstract:
A compound of the formula: whereinR1 and R2 are individually selected from the group consisting of hydrogen, or R1 and R2 together form a bond, â€”CH2â€”, â€”Oâ€”, â€”NHâ€” or â€”Nâ€”R3, R3 is lower alkyl or â€”CH2â€”Ar, and Ar is selected from the group consisting of unsubstituted phenyl; unsubstituted naphthyl; phenyl mono- or bi-substituted with lower alkyl, lower alkoxy, aryl, cycloalkyl, lower alkyl-aryl, lower alkoxy-aryl, lower alkyl-cycloalkyl, lower alkoxy-cycloalkyl, halo, cyano or trifluoromethyl; and naphthyl mono- or bi-substituted with lower alkyl, lower alkoxy, aryl, cycloalkyl, lower alkyl-aryl, lower alkoxy-aryl, lower alkyl-cycloalkyl, lower alkoxy-cylcoalkyl or halo; or pharmaceutically acceptable salts thereof.