Patent ID: 6291163
Filing Date: 2001-09-18
Classification: C12Q

Abstract:
A method for detecting cancer or precancer in a subject, the method comprising:a) amplifying test sample DNA at a genetic locus for which the subject is heterozygous, wherein the genetic locus comprises a first and second alleles, said genetic locus comprising microsatellite DNA, wherein the test sample DNA is from a cell of an organ which drains into the test samples, wherein the test sample is selected from the group consisting of the subject's: urine, sputum, bile, stool, saliva, tears, serum and plasma; andb) detecting an allelic imbalance at the genetic locus by determining and comparing level of microsatellite DNA present at the first allele to level of microsatellite DNA present at the second allele, wherein an allelic imbalance is indicative of cancer or precancer.