Patent ID: 8461329
Filing Date: 2013-06-11
Classification: A61P,C07D

Abstract:
1. A compound represented by formula (I): wherein R 1 represents a C 1-6 alkyl group, a C 2-6 alkenyl group, a C 3-6 cycloalkyl group, a C 3-6 cycloalkenyl group, an adamantyl group, an indanyl group, a tetrahydronaphthyl group, a tetrahydroindolyl group, a tetrahydropyranyl group, a morpholinyl group, a phenyl group, a naphthyl group, or an aromatic heterocyclic group, wherein the phenyl group, the naphthyl group, and the aromatic heterocyclic group may be substituted with 1 to 5 substituent(s) selected from the group consisting of a C 1-6 alkyl group, a C 2-6 alkenyl group, a C 3-6 cycloalkyl group, a halogen atom, a C 1-6 alkoxy group, a hydroxy group, a C 1-6 alkylthio group, a C 1-6 haloalkyl group, a C 1-6 haloalkoxy group, a C 1-6 haloalkylthio group, a cyano group, a nitro group, a guanidino group, a C 1-6 alkylsulfonyl group, a carboxy group, a C 2-7 alkoxycarbonyl group, a C 2-7 alkanoyloxy group, a phenyl group, a benzoyl group, a phenoxy group, a pyrrolyl group, a thienyl group, an imidazolyl group, a thiadiazolyl group, a morpholino group, the formula: —NR 5 R 6 , the formula: —SO 2 NR 7 R 8 , the formula: —NR 9 SO 2 R 10 , the formula: —CONR 11 R 12 , and the formula: —NR 13 COR 14 , wherein R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , R 13 , and R 14 each independently represent a hydrogen atom or a C 1-6 alkyl group; X represents an oxygen atom, a sulfur atom, the formula: —CH Y represents a single bond, the formula: —NR wherein R Z represents a benzene ring, a pyrimidine ring, or a pyrazine ring; R R R or a pharmaceutically acceptable salt thereof.