Patent ID: 8283131
Filing Date: 2012-10-09
Classification: G01N

Abstract:
1. A method for in vitro establishing a prognosis for a subject in severe sepsis with at least two organ failures or in septic shock with at least two organ failures, consisting of the following steps: (i) from a plasma sample from said subject, measuring the level of S100A8/A9 complex in said sample, by immunoassay; (ii) comparing said level to a predetermined threshold plasma level of S100A8/A9 complex indicative for risk of death, wherein: if the level of S100A8/A9 complex in the plasma sample is above said predetermined threshold, the prognosis is that the subject will not survive said severe sepsis or said septic shock; and if the level of S100A8/A9 complex in the plasma sample is below said predetermined threshold, the prognosis is that the subject will survive said severe sepsis or said septic shock.