Patent ID: 7329388
Filing Date: 2008-02-12
Classification: G01N,Y10T

Abstract:
1. An electrophoresis apparatus, comprising: a transport capillary or channel; a first separation capillary or channel overlapping and intersecting the transport capillary or channel at a first intersection; the first intersection having a first staggered configuration which includes a first elongated concentration area; a first analyte concentrator containing at least one first immobilized affinity ligand in the first elongated concentration area to concentrate a first analyte of interest from a sample introduced into the transport capillary or channel; a second separation capillary or channel overlapping and intersecting the transport capillary or channel at a second intersection spaced downstream from the first intersection; the second intersection having a second staggered configuration which includes a second elongated concentration area; a second analyte concentrator containing at least one second immobilized affinity ligand in the second elongated concentration area to concentrate a second analyte of interest from the sample introduced into the transport capillary or channel; analyte detector means for identifying and characterizing the first and second analytes of interest conveyed thereto from the first and second analyte concentrators, respectively; and controlling means for controlling flow of the sample in the transport capillary or channel and past the first and second intersections and for controlling flow of buffer fluid through the first and second separation capillaries or channels and conveyed by electrophoresis migration, pressure or a combination of electrophoresis migration and pressure to the analyte detector means.