Patent ID: 8987420
Filing Date: 2015-03-24
Classification: A61K,A61M,A61P,C07K

Abstract:
1. An isolated antibody or antigen-binding fragment thereof that specifically binds human angiopoietin-2 (hAng-2), wherein the antibody or antigen-binding fragment thereof comprises a heavy chain CDR-1 (HCDR1) having the amino acid sequence of SEQ ID NO:4, an HCDR-2 having the amino acid sequence of SEQ ID NO:6, an HCDR-3 having the amino acid sequence of SEQ ID NO:8, a light chain CDR-1 (LCDR-1) having the amino acid sequence of SEQ ID NO:12, an LCDR-2 having the amino acid sequence of SEQ ID NO:14, and an LCDR-3 having the amino acid sequence of SEQ ID NO:16.