Patent ID: 6287573
Filing Date: 2001-09-11
Classification: A61K,A61P,C07K

Abstract:
An injectable vaccine for treatment of Pythiosis in a mammal including an equine and a human which comprises in a sterile aqueous solution an admixture of:(a) intracellular proteins separated from disrupted cells of Pythium insidiosum grown in culture medium and from extracellular proteins; and(b) extracellular proteins including 28, 30 and 32 kD proteins as determined by SDS-PAGE electrophoresis in a supernatant from the culture medium for growing the cells of the Pythium insidiosum which has been separated from the cells wherein the proteins in the admixture of the separated intracellular and extracellular proteins have been mixed with sterile distilled water and dialyzed to remove components less than 10,000 MW, wherein the vaccine is able to cure acute and chronic infections in the mammal including an equine or the human.