Patent ID: 8354109
Filing Date: 2013-01-15
Classification: A61P,C07K,Y10S

Abstract:
1. A soluble multimeric protein or polypeptide able to inhibit interaction of leukocyte Fcγ receptors (FcγR) and immunoglobulin G (IgG), said protein or polypeptide consisting of: i) two linked Fc binding regions derived from an FcγR type receptor, wherein said Fc binding regions are linked in a head to tail arrangement; and ii) optionally a linker, wherein said Fc binding regions are linked through the optional linker and wherein said linker comprises from 1 to 20 amino acids; iii) optionally an amino acid tag motif, and wherein none of said linked Fc binding regions is fused to an Fc region of an immunoglobulin.