Patent ID: 6180644
Filing Date: 2001-01-30
Classification: A61P,C07D

Abstract:
A compound of the formula: ##STR5##in which:one of R.sup.1 and R.sup.2 is R.sup.3 --X-- and the other is hydrogen, nitro, cyano, trifluoromethyl, carbethoxy, carbomethoxy, carbopropoxy, acetyl, carbamoyl, acetoxy, carboxy, hydroxy, amino, lower alkyl, lower alkoxy, halo, or R.sup.3 --X--;R.sup.3 is monocycloalkyl of up to 10 carbon atoms, polycycloalkyl of up to 10 carbon atoms, or benzocyclic alkyl of up to 10 carbon atoms;X is --CH.sub.2 -- or --O--;R.sup.5 is pyridine-2,3-diyl, pyridine-3,4-diyl, pyridine-4,5-diyl, or pyridine-5,6-diyl;R.sup.6 is --CO--, --CH.sub.2 --, or --SO.sub.2 --;Y is --COX, --C.tbd.N, --OR.sup.8, alkyl of 1 to 5 carbon atoms, or aryl;X is --NH.sub.2, --OH, --NHR, --R.sup.9, --OR.sup.9, or alkyl of 1 to 5 carbon atoms;R.sup.8 is hydrogen or lower alkyl;R.sup.9 is alkyl or benzyl; and,n has a value of 0, 1, 2, or 3.