Patent ID: 6699377
Filing Date: 2004-03-02
Classification: C07K,G01N

Abstract:
A microfluidics device comprisinga substrate having an upper surface, a channel network formed in the substrate, including a source channel adapted to contain a sample, a drain channel, and an electrolyte channel adapted to contain an electrolyte buffer, wherein said source and drain channels are each inclined with respect to the electrolyte channel, and which source and drain channels intersect said electrolyte channel at a source port and a drain port, respectively, wherein movement of sample material from the source to the drain channel is effective to place a sample volume between the source and drain ports in the electrolyte channel, a lid covering said substrate and enclosing said channels, and a plurality of waveguide ports formed in said lid at a plurality of positions along the electrolyte channel, downstream of the source and drain ports, through which an optical detection system can detect the optical properties of sample components moving through electrolyte channel at a plurality of different positions along the channel.