Patent ID: 7947812
Filing Date: 2011-05-24
Classification: A61P,C07K

Abstract:
1. A purified antibody or binding fragment thereof, wherein the heavy chain variable region sequence comprises amino acids 16-22, 37-52, and 85-103 of SEQ ID NO:2, and wherein the antibody or binding fragment thereof specifically binds to an epitope of a polypeptide having an apparent molecular weight of approximately 70 kDa using sodium dodecyl sulfate polyacrylamide gel electrophoresis, wherein said polypeptide is expressed by at least one of lung adenocarcinoma cell line Colo-699 (DSMZ accession number ACC 196), lung adenocarcinoma cell line DV-90 (DSMZ accession number ACC 307), epidermoid lung carcinoma cell line EPLC-272H (DSMZ accession number ACC 383) or lung squamous cell carcinoma cell line LOU-NH91 (DSMZ accession number ACC 393).