Patent ID: 6340700
Filing Date: 2002-01-22
Classification: A61P,C07C,C07D

Abstract:
A compound selected from the group consisting of a compound of the formula wherein A is R1 and R2 are individually selected from the group consisting of hydrogen, halogen, â€”OH, alkyl of 1 to 6 carbon atoms and alkoxy of 1 to 6 carbon atoms, R3 is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms and â€”COR4, R4 is alkyl of 1 to 6 carbon atoms, B is selected from the group consisting of thiophene, furan, and pyrrole, X is selected from the group consisting of â€”Z1â€”, â€”Z1COâ€”, â€”CH&boxH;CH&boxH;COâ€”, â€”Z1NR3â€”COâ€”, â€”Zâ€”NR3â€”CSâ€”, â€”Z1NR3â€”SO2â€” and a single bond, Y is selected from the group consisting of â€”Z2â€”Qâ€”, â€”NR3â€”Z2â€”Qâ€”, â€”NR3â€”COâ€”Z2â€”Q, â€”NR3â€”NHâ€”COâ€”Z2â€”, â€”NHâ€”NHâ€”Z2â€”, â€”NR3â€”Oâ€”Z2â€”, â€”NR3â€”SO2â€”NR3â€”Z2â€”, â€”OZ2â€”Qâ€”, â€”Oâ€”COâ€”Z2â€”Qâ€” and â€”Sâ€”Z3â€”Qâ€”, Q is selected from the group consisting of a single bond, â€”OZ3â€”, â€”SZ2â€” and â€”NR3â€”Z3, Z1, Z2 and Z3 are individually selected from the group consisting of a single bond and alkylene of 1 to 6 carbon atoms, R6 is hydrogen or â€”OH and its non-toxic, pharmaceutically acceptable salts with the proviso that it is not the compound of the formula