Patent ID: 7858835
Filing Date: 2010-12-28
Classification: A61L,C08G,C08L,C09J

Abstract:
1. A method comprising: reacting a first polyol selected from the group consisting of polyether polyols, polycaprolactone polyols, and polyhydric alcohols with a first polyisocyanate selected from the group consisting of aromatic, aliphatic and alicyclic diisocyanates, to produce an isocyanate end-capped polyol; reacting the isocyanate end-capped polyol with a second polyol to produce a polyurethane; reacting the polyurethane with a second polyisocyanate to produce at least one isocyanate-functional polyurethane prepolymer; contacting the at least one isocyanate-functional polyurethane prepolymer with at least one foam control agent; applying the at least one isocyanate-functional polyurethane prepolymer with at least one foam control agent to tissue; and allowing the at least one isocyanate-functional polyurethane prepolymer to react with the tissue, wherein the at least one isocyanate-functional polyurethane prepolymer crosslinks upon contact with water in the tissue thereby forming a biocompatible composition possessing a strength profile that is not compromised by the presence of the foam control agent.