Patent ID: 6210716
Filing Date: 2001-04-03
Classification: A61K,A61P

Abstract:
A controlled release dosage form of bupropion hydrochloride which comprises:(a) a first pellet having a core which comprises bupropion hydrochloride and hydroxypropyl methylcellulose at a weight ratio of 10:1 to 30:1 and a coating which comprises a mixture of an acrylic resin which is soluble in acidic media and ethyl cellulose;(b) a second pellet having a core which comprises bupropion hydrochloride and hydroxypropyl methylcellulose at a ratio of 10:1 to 30:1; an inner coating which comprises a mixture of an acrylic resin which is soluble in acidic media and a water insoluble polymer and an outer coating which comprises an enteric coating polymer.