Patent ID: 9040727
Filing Date: 2015-05-26
Classification: A61P,C07C,C07D

Abstract:
1. A compound selected from the group consisting of: V-1 N-(4-(2-aminophenylaminocarbonyl)phenyl)-2-naphthamide, V-2 N-(4-(2-amino-5-fluorophenylaminocarbonyl)phenyl)-2-naphthamide, V-2′ N-(4-(2-amino-5-fluorophenylaminocarbonyl)phenyl)-2-naphthamide hydrochloride, V-3 N-(4-(2-aminophenylaminocarbonyl)phenyl)-6-methoxy-2-naphthamide, V-4 N-(4-(2-amino-5-fluorophenylaminocarbonyl)phenyl)-6-methoxy-2-naphthamide, V-5 N-(4-(2-aminophenylaminocarbonyl)phenyl)-1H-indole-2-carboxamide, V-5′ N-(4-(2-aminophenylaminocarbonyl)phenyl)-1H-indole-2-carboxamide hydrobromide, V-6 N-(4-(3-aminopyridine-4-carbamoyl)phenyl)-1H-indole-2-carboxamide, V-6′ N-(4-(3-aminopyridine-4-carbamoyl)phenyl)-1H-indole-2-carboxamide sulfate, V-7 N-(4-(2-amino-5-fluorophenylaminocarbonyl)phenyl)-1H-indole-2-carboxamide, V-8 N-(4-(2-aminophenylaminocarbonyl)phenyl)benzofuran-2-carboxamide, V-8′ N-(4-(2-aminophenylaminocarbonyl)phenyl)benzofuran-2-carboxamide mesylate, V-9 N-(4-(2-amino-5-fluorophenylaminocarbonyl)phenyl)benzofuran-2-carboxamide, V-10 N-(4-(2-amino-5-thienylphenylaminocarbonyl)phenyl)benzofuran-2-carboxamide, V-11 N-(4-(2-amino-5-phenylphenylaminocarbonyl)phenyl)benzofuran-2-carboxamide, V-12 N-(4-(2-aminophenylaminocarbonyl)phenyl)-1H-benzimidazol-2-carboxamide, V-13 N-(4-(2-amino-5-fluorophenylaminocarbonyl)phenyl)-1H-benzimidazol-2-carboxamide, V-13′ N-(4-(2-amino-5-fluorophenylaminocarbonyl)phenyl)-1H-benzimidazol-2-carboxamide trifluoroacetate, V-14 N-(4-(2-amino-5-furylphenylaminocarbonyl)phenyl)-1H-benzimidazol-2-carboxamide, V-15 N-(4-(2-aminophenylaminocarbonyl)phenyl)-1-naphthamide, V-16 N-(4-(3-aminopyridine-4-carbamoyl)phenyl)-1-naphthamide, V-17 N-(4-(2-amino-5-fluorophenylaminocarbonyl)phenyl)-1-naphthamide, V-18 N-(4-(2-aminophenylaminocarbonyl)phenyl)-5-fluoro-1H-indole-2-carboxamide, V-18′ N-(4-(2-aminophenylaminocarbonyl)phenyl)-5-fluoro-1H-indole-2-carboxamide malate, V-19 N-(4-(2-aminophenylaminocarbonyl)phenyl)-5-methyl-1H-indole-2-carboxamide, V-20 N-(4-(2-aminophenylaminocarbonyl)phenyl)-5-trifluoromethyl-1H-indole-2-carboxamide, V-20′ N-(4-(2-aminophenylaminocarbonyl)phenyl)-5-trifluoromethyl-1H-indole-2-carboxamide maleate, V-21 N-(4-(2-aminophenylaminocarbonyl)phenyl)-3-methoxybenzofuran-2-carboxamide, V-22 N-(4-(2-aminophenylaminocarbonyl)phenyl)-5-methylamino-1H-indole-2-carboxamide, V-23 N-(4-(2-aminophenylaminocarbonyl)phenyl)-5-amino-1H-indole-2-carboxamide, V-24 N-(4-(2-aminophenylaminocarbonyl)phenyl)benzothiophene-2-carboxamide, V-25 5-acetamido-N-(4-(2-aminophenylaminocarbonyl)phenyl)-1H-indole-2-carboxamide, V-26 5-acetyl-N-(4-(2-aminophenylaminocarbonyl)phenyl)-1H-indole-2-carboxamide, V-27 N-(4-(2-amino-5-fluorophenylaminocarbonyl)phenyl)benzothiophene-2-carboxamide, and V-28 N-(4-(3-aminopyridine-4-carbamoyl)phenyl)benzothiophene-2-carboxamide; and salts thereof.