Patent ID: 9206183
Filing Date: 2015-12-08
Classification: A61K,A61P,C07D

Abstract:
1. A compound of formula (I), or a pharmaceutically acceptable salt, or N-oxide, or stereoisomer thereof: wherein T is —CR m is chosen from 0, 1, 2, or 3; Z is chosen from an oxygen atom or NR W is —CR X and Y are independently chosen from a nitrogen atom or —CR R wherein each of the alkenyl, alkynyl, haloalkyl, hydroxyalkyl, cycloalkyl, cycloalkenyl, aryl, heteroaryl, heterocyclyl, bicyclyl, aza-bicycloalkyl and aza-bicycloalkenyl is independently unsubstituted or substituted by at least one substituent chosen from Ra, and each of the alkyl groups is independently unsubstituted or substituted by at least one Rb; or R R or when two adjacent —CR R R R wherein each of the alkenyl, alkynyl, haloalkyl, hydroxyalkyl, cycloalkyl, cycloalkenyl, aryl, heteroaryl, heterocyclyl, bicyclyl, aza-bicycloalkyl and aza-bicycloalkenyl is independently unsubstituted or substituted by at least one substituent chosen from Ra, —(C and when R or R or R wherein each of the alkyl, aryl, heteroaryl and heterocyclyl is independently unsubstituted or substituted by at least one substituent chosen from halogen atoms, hydroxyl, cyano, linear or branched C with the proviso that when m is zero, R is not —SR wherein each Ra is independently chosen from halogen atoms, cyano, hydroxyl, linear or branched C each Rb is independently chosen from cyano, C R each Rc is independently chosen from halogen atoms, hydroxyl, cyano, linear or branched C each Rd is independently chosen from cyano, C each Re is independently chosen from halogen atoms, hydroxyl, cyano, linear or branched C R