Patent ID: 7727982
Filing Date: 2010-06-01
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A compound of the formula: wherein: A is a 5-10 membered saturated monocyclic heterocyclic ring system containing 1-4 heteroatoms selected from N, O and S, wherein 1-2 ring atoms of the heterocyclic ring system are substituted with 1-2 R R D is phenyl or pyridine where the phenyl is attached to rest of the compound in the 1,4-position and the pyridine is attached to the rest of the compound in the 2,5-position; E is —C(═O)—NH— or —NH—C(═O)—; G is a phenylene group wherein the ring carbon atoms of the phenylene group are substituted with 0-2 R R R J is —C(═O)—NH— or —NH—C(═O)—; K is a phenyl substituted with 0-3 R R R or a pharmaceutically acceptable isomer, salt, hydrate, or prodrug derivative thereof.