Patent ID: 6177469
Filing Date: 2001-01-23
Classification: A61K,A61P,C07C

Abstract:
A pharmaceutical composition, comprising a compound of formula I or II ##STR4##whereinR.sup.1 is a straight-chained or branched, saturated or unsaturated C.sub.1 -C.sub.30 alkyl, which is unsubstituted or has at least one substituent each independently selected from the group consisting of halogen, C.sub.1 -C.sub.6 alkoxy, C.sub.1 -C.sub.6 alkylmercapto, C.sub.1 -C.sub.6 alkoxycarbonyl, carboxy, C.sub.1 -C.sub.6 alkylsulfinyl and C.sub.1 -C.sub.6 alkylsulfonyl; andR.sup.2 is hydrogen or a straight-chained or branched, saturated or unsaturated C.sub.1 -C.sub.20 alkyl, which is unsubstituted or has at least one substituent each independently selected from the group consisting of halogen, C.sub.1 -C.sub.6 alkoxy, C.sub.1 -C.sub.6 alkylmercapto, C.sub.1 -C.sub.6 alkoxycarbonyl and C.sub.1 -C.sub.6 alkylsulfonyl,provided, however, that eitherR.sup.1 is a straight-chained or branched, saturated C.sub.7 -C.sub.18 alkyl, which is unsubstituted or has at least one substituent each independently selected from the group consisting of halogen, C.sub.1 -C.sub.6 alkoxy, C.sub.1 -C.sub.6 alkylmercapto and C.sub.1 -C.sub.6 alkylsulfonyl; orR.sup.2 is a straight-chained or branched, saturated C.sub.6 -C.sub.16 alkyl, which is unsubstituted or has at least one substituent each independently selected from the group consisting of halogen, C.sub.1 -C.sub.6 alkoxy and C.sub.1 -C.sub.6 alkylmercapto;X is selected from the group consisting of a bond, oxycarbonyl, carbonyloxy, amidocarbonyl, carbonylamido, oxygen, sulfur, sulfinyl and sulfonyl;Y is selected from the group consisting of a bond, oxycarbonyl, carbonyloxy, amidocarbonyl, carbonylamido, oxygen, sulfur, sulfinyl and sulfonyl; andn is 1-5,or a tautomer or optically active form thereof, in combination with a pharmaceutically acceptable carrier.