Patent ID: 8987250
Filing Date: 2015-03-24
Classification: A61K,A61P,C07D

Abstract:
1. A compound, or a pharmaceutically acceptable salt thereof, of formula I′: wherein: R A is phenyl, 6-membered N-heteroaryl, thiazolyl, pyridinyl-2(1H)-one, tetrahydropyrimidin-2(1H)-one, imidazolidinyl-2-one, pyrrolidinyl-2-one, pyrrolidinyl, pyrazin-2(1H)-one, piperazinyl-2-one, piperazinyl, morpholinyl, or piperidinyl, wherein A is optionally substituted with 1 to 5 Z B is (C each Z each Z R wherein each heteroaryl, as a monocyclic ring or portion of a 2 to 3 ring system, has 1 to 6 carbon atoms and 1 to 4 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur, and each heterocycle, as a monocyclic ring or portion of a 2 to 3 ring system, has 1 to 6 carbon atoms and 1 to 3 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur.