Patent ID: 6355630
Filing Date: 2002-03-12
Classification: A61P,C07J

Abstract:
A compound of formula I having the stucture wherein:R is R1 and R2 are each, independently, alkyl of 1-6 carbon atoms, or are alkyl groups which are taken together to form a 5-7 membered saturated heterocycle; X is hydroxy, alkoxy of 1-6 carbon atoms, or â€”OC(O)R3; W is â€ƒhydroxy, alkyl of 1-6 carbon atoms, halogen, â€”CF3, alkoxy of 1-6 carbon atoms, â€”CHO, cyano, alkylcarbonyl of 2-7 carbon atoms, alkoxycarbonyl of 2-7 carbon atoms, amino, alkylamino of 1-6 carbon atoms, dialkylamino of 1-6 carbon atoms per alkyl group, trifluoromethoxy, hydroxyalkyl of 1-6 carbon atoms, alkoxyalkyl of 2-12 carbon atoms, â€”CN, â€”SO3H, or â€”CO2H; R3 is alkyl of 1-6 carbon atoms; R4 is hydrogen, alkyl of 1-6 carbon atoms, alkoyl of 2-7 carbon atoms, or benzoyl; Q is hydrogen, â€”OR5, or â€”NR6R7; R5 is hydrogen or alkyl of 1-6 carbon atoms; R6 and R7 are each, independently, alkyl of 1-6 carbon atoms, or are alkyl groups which are taken together to form a 5-7 membered saturated heterocycle; n=4-12; and p=2-6; or a pharmaceutically acceptable salt thereof.