Patent ID: 6660526
Filing Date: 2003-12-09
Classification: C07D,G01N

Abstract:
A compound, having the structure: wherein(a) R is selected from the group consisting, independently or in combination, of hydrogen, alkyl, alkenyl, alkynyl, alkoxy, ether, acyl, carboxylic acid, carboxylic ester, unsubstituted aryl substituted aryl, aryloxy, heteroaryl, and heteroaryloxy groups, wherein the heteroatom is selected from nitrogen and sulfur; (b) W is â€”O(CH2)2O(CH2)2â€”; (c) X is selected from the group consisting, independently or in combination, of nitrogen, saturated alkyl, unsaturated alkyl, unsubstituted aryl, and substituted aryl, wherein the aryl group may contain a heteroatom selected from the group consisting of nitrogen, sulfur and oxygen; (d) Y is selected from the group consisting, independently or in combination, of saturated alkyl, unsaturated alkyl, unsubstituted aryl, substituted aryl, ether, carboxylic acid, carboxylic ester, secondary amine and sulfur; and (e) Z is a fluorophore, wherein a negative, thermo-neutral or slightly positive free energy value is obtained from the Rehm-Weller equation for the compound.