Patent ID: 8993343
Filing Date: 2015-03-31
Classification: A61K,A61P,G01N

Abstract:
1. A method for diagnosing rheumatoid arthritis comprising: coating proteins from a biological sample obtained from synovial fluid and a control on a fixture; inducing an antigen-antibody reaction by adding an antibody specifically binding to a CD93 soluble fragment to the above fixture; detecting the antigen-antibody reaction product produced by the above antigen-antibody reaction by using a secondary antibody conjugate marker and chromogenic substrate solution; comparing the detection results between the biological sample and the control; and diagnosing rheumatoid arthritis or high risk of rheumatoid arthritis when CD93 soluble fragment is up-regulated in the biological sample, compared with the level in the control, wherein the antigen-antibody reaction product is measured by a sandwich ELISA.