Patent ID: 6403325
Filing Date: 2002-06-11
Classification: A61K,A61P,C07K,G01N

Abstract:
A method of identifying a compound that inhibits A&bgr; peptide levels, the method comprising:contacting the compound with a protein selected from the group consisting of: a) Hfz5 (SEQ ID NO:4), b) Mfz4 (SEQ ID NO:6), c) Mfz7 (SEQ ID NO:8), d) Mfz7 (SEQ ID NO: 10), e) hfiz (SEQ ID NO: 12); and f) mfiz (SEQ ID NO: 14) and determining the ability of the compound to bind to the protein, wherein the binding ability of the compound is an indication that the compound lowers levels of A&bgr; peptide.