Patent ID: 6691042
Filing Date: 2004-02-10
Classification: G16B

Abstract:
A method for generating an error-corrected differential profile A vs. B from sets of data A, B, CA, and CB, comprising(a) calculating a first differential profile A vs. B; (b) determining a systematic cross-experiment error by a method comprising calculating a reference differential profile CA vs. CB; and (c) generating a second differential profile A vs. B by a method comprising correcting said first differential profile A vs. B using said determined systematic cross-experiment error; wherein said data set A, B, CA or CB comprises respectively data set {A(i)}, {B(i)}, {CA(i)}or {CB(i)}, said data set {A(i)}representing measurements of a plurality of different cellular constituents measured in a sample having been subject to condition A, said data set {B(i)}representing measurements of said plurality of different cellular constituents measured in a sample having been subject to condition B, and said data sets {CA(i)}and {CB(i)}each representing measurements of said plurality of different cellular constituents measured in a sample having been subject to condition C, wherein i=1, 2, . . . , N is the index of measurements of cellular constituents, N being the total number of measurements; wherein data sets A and CA are measured in the same experimental reaction, and data sets B and CB are measured in the same experimental reaction; and wherein said second differential profile is taken as said error-corrected differential profile A vs. B.