Patent ID: 6063373
Filing Date: 2000-05-16
Classification: A61K,C12N,Y10S

Abstract:
A method for treating neoplastic disease comprising the steps of:administering to a patient receiving radiation therapy or chemotherapy, an effective amount of an NK cell activating cytokine, wherein said cytokine is selected from the group consisting of Interleukin-1 (IL-1), Interleukin-2 (IL-2), Interleukin-12 (IL-12), Interleukin-15 (IL-15), Interferon-.alpha., Interferon-.beta. (IFN-.beta.); and Interferon-.gamma. (IFN-.gamma.); or an NK cell activating flavonoid, wherein said flavonoid is selected from the group consisting of flavone-8-acetic acid (FAA) and xanthenone4-acetic acid (XAA); andadministering to the patient a compound effective to inhibit the production or release of intracellular hydrogen peroxide selected from histamine, other H.sub.2 receptor agonist and serotonin.