Patent ID: 7678539
Filing Date: 2010-03-16
Classification: B01J,B82Y,C07K,C40B,G01N

Abstract:
1. A method for detecting a binding event between a probe and target compound, said method comprising: contacting a solution comprising the target compound with an air-dried array of immobilized probe biological membrane microspots, at least one of the biological membrane microspots comprising at least one G-protein coupled receptor, wherein the membrane microspots are directly and noncovalently associated with a γ-aminopropyl-silane layer disposed directly on a surface of a glass substrate, such that the microspots remain adsorbed on said layer and retain biological function when drawn through an air-water interface, the target compound having one or more constituents; and detecting a binding event between at least one or more of the probes and one or more of the constituents of the target.