Patent ID: 8927530
Filing Date: 2015-01-06
Classification: A61K,A61P

Abstract:
1. A combination comprising a synergistic amount of (a) a compound of formula (I) and (b) one or more antineoplastic agents selected from the group consisting of an antimetabolite agent, an alkylating or an alkylating-like agent, an intercalating agent, a topoisomerase I or II inhibitor, an antimitotic agent, a kinase inhibitor, a proteasome inhibitor and an antibody inhibiting a growth factor or its receptor, wherein the active ingredients of the combination are present in each case in free form or in the form of a pharmaceutically acceptable salt or any hydrate or solvate thereof, wherein the topoisomerase I inhibitor is selected from the group consisting of topotecan, SN-38, CPT11 and 9-nitrocamptothecin.