Patent ID: 6077840
Filing Date: 2000-06-20
Classification: A61P,C07D

Abstract:
A compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof: ##STR267## wherein R.sup.1 representsa hydrogen atom,optionally substituted C.sub.1 -C.sub.10 alkyl,optionally substituted C.sub.2 -C.sub.10 alkenyl,optionally substituted C.sub.2 -C.sub.10 alkynyl,optionally substituted C.sub.3 -C.sub.10 cycloalkyl, oroptionally substituted C.sub.7 -C.sub.15 aralkyl;R.sup.2 representsa hydrogen atom,optionally substituted C.sub.1 -C.sub.10 alkylcarbonyl,optionally substituted C.sub.2 -C.sub.10 alkenylcarbonyl,optionally substituted C.sub.2 -C.sub.10 alkynylcarbonyl,optionally substituted C.sub.3 -C.sub.15 cycloalkylcarbonyl,optionally substituted C.sub.7 -C.sub.15 aralkylcarbonyl,optionally substituted C.sub.7 -C.sub.15 aromatic acyl,optionally substituted C.sub.2 -C.sub.15 heteroaromatic acyl having at least one hetero atom selected from the group consisting of nitrogen, oxygen, and sulfur atoms,optionally substituted C.sub.3 -C.sub.15 saturated heterocyclic acyl having at least one hetero atom selected from the group consisting of nitrogen, oxygen, and sulfur atoms,optionally substituted C.sub.1 -C.sub.10 alkyl,optionally substituted C.sub.2 -C.sub.10 alkenyl,optionally substituted C.sub.2 -C.sub.10 alkynyl,optionally substituted C.sub.3 -C.sub.10 cycloalkyl,optionally substituted C.sub.7 -C.sub.15 aralkyl, carbamoyl,optionally substituted N--C.sub.1 -C.sub.10 alkylcarbamoyl,optionally substituted N--C.sub.6 -C.sub.15 aromatic carbamoyl,optionally substituted N--C.sub.7 -C.sub.15 aralkylcarbamoyl,optionally substituted N,N-di-C.sub.1 -C.sub.10 alkylaminocarbonyl,optionally substituted N--C.sub.3 -C.sub.10 cycloalkylcarbamoyl,optionally substituted C.sub.1 -C.sub.10 alkoxycarbonyl,optionally substituted C.sub.6 -C.sub.15 aryloxycarbonyl,optionally substituted C.sub.7 -C.sub.15 aralkyloxycarbonyl,optionally substituted C.sub.1 -C.sub.15 heteroaromatic thiocarbonyl having at least one hetero atom selected from the group consisting of nitrogen, oxygen, and sulfur atoms,optionally substituted C.sub.2 -C.sub.15 saturated heterocyclic thiocarbonyl having at least one hetero atom selected from the group consisting of nitrogen, oxygen, and sulfur atoms, oroptionally substituted N--C.sub.1 -C.sub.10 alkyl-thiocarbamoyl; andR.sup.3 representsa hydrogen atom,a hydroxyl group,optionally substituted C.sub.1 -C.sub.10 alkyloxy,optionally substituted C.sub.2 -C.sub.10 alkenyloxy,optionally substituted C.sub.2 -C.sub.10 alkynyloxy,optionally substituted C.sub.3 -C.sub.10 cycloalkyloxy,optionally substituted C.sub.7 -C.sub.15 aralkyloxy,optionally substituted C.sub.1 -C.sub.10 alkylcarbonyloxy,optionally substituted C.sub.2 -C.sub.10 alkenylcarbonyloxy,optionally substituted C.sub.2 -C.sub.10 alkynylcarbonyloxy,optionally substituted C.sub.3 -C.sub.10 cycloalkylcarbonyloxy,optionally substituted C.sub.7 -C.sub.15 aromatic acyloxy,optionally substituted C.sub.7 -C.sub.15 aralkylcarbonyloxy,optionally substituted C.sub.1 -C.sub.10 alkylthio,optionally substituted C.sub.2 -C.sub.10 alkenylthio,optionally substituted C.sub.2 -C.sub.10 alkynylthio,optionally substituted C.sub.3 -C.sub.10 cycloalkylthio,optionally substituted C.sub.6 -C.sub.15 arylthio, oroptionally substituted C.sub.7 -C.sub.15 aralkylthio.