Patent ID: 7833550
Filing Date: 2010-11-16
Classification: A61K,A61P

Abstract:
1. A composition for the nasal administration of a drug to a patient comprising a drug in a dry powder form in a dosage formulation suitable for administration to the nasal mucosa, the dry powder made by a process comprising the following steps: providing preformed diketopiperazine microparticles between 10 and 20 microns in diameter; suspending said diketopiperazine microparticles in an aqueous medium with a drug to form a suspension; and forming drug-coated diketopiperazine microparticles by removing solvent from said suspension, wherein said drug-coated diketopiperazine microparticles are between about 10 and about 20 microns in diameter, more than 50% of the particles have a size greater than about 10 microns, and wherein said particles are maximally retained in the nasal cavity.