Patent ID: 9150550
Filing Date: 2015-10-06
Classification: A61P,C07D

Abstract:
1. A method of treating a disease or condition mediated by CCR(4) signalling, said method comprising administering to a subject in need thereof an efficacious amount of a compound of formula (I): or a pharmaceutically acceptable salt thereof wherein: the dashed bond indicates a single or double bond; R R R R the subscripts n are each independently selected from the group consisting of 0, 1, 2 and 3; the subscript m is 1; each A is independently C or N, and at least one A is N; B is C(O), Q, W and Z are independently C, CH, or N with the exception that Q and W may not both N in the same compound; X is C, CH or N; Y is N; R R R R R R wherein said disease or condition is selected from the group consisting of allergic diseases, inflammatory bowel diseases, vaginitis, psoriasis, inflammatory dermatoses, vasculitis, spondyloarthropathies, scleroderma, asthma, graft rejection, and renal cancer.