Patent ID: 6239143
Filing Date: 2001-05-29
Classification: C07D

Abstract:
A compound of formula (I): ##STR52##or a stereoisomer or pharmaceutically acceptable salt form thereof, wherein:R.sup.1 is selected from a C.sub.6-10 carbocyclic aromatic residue substituted with 1-3 R.sup.1a, and a 5-10 membered aromatic heterocyclic system containing from 1-4 heteroatoms selected from N, O, and S, substituted with 0-2 R.sup.1a ;R.sup.1 a is independently selected at each occurrence from halo, --NO.sub.2, --CN, --CF.sub.3 and --CF.sub.2 CF.sub.3 ; X is selected from --C(O)--, --CH(OH)--, and --CH(OC(O)CH.sub.3)--;R.sup.4 is selected from hydrogen and C.sub.16 alkyl:R.sup.4 a is taken together with Rl to form a 5 or 6-membered fused heterocyclic ring containing 1-2 heteroatoms selected from O and N, substituted with 1 or 2 carbonyl groups;Y is C.sub.1-3 alkylene;A is a 6 membered saturated or partially saturated ring fused with ring B, substituted with 0-3 R.sup.5 ;R.sup.5 is selected from C.sub.1-5 alkyl, halo and --OCH.sub.3 ; andn is 2.