Patent ID: 8399486
Filing Date: 2013-03-19
Classification: A61P,C07D

Abstract:
1. A compound having the Formula I: or a pharmaceutically acceptable salt thereof, wherein: R R Z is selected from the group consisting of Z Z 1 is Z 2 is and Z 3 is m is 0, 1, or 2; n is 0, 1 or 2; p is 0 or 1; r is 0 or 1; provided that n and p are not both 0; R R R R R R where A is CH B is CH s is 0, 1, or 2; p is 0 or 1; R R R (i) R R R R R R R R R (ii) R R R where A is CH B is CH s is 0, 1, or 2; r is 0 or 1; and R R (iii) R D is CH E is CH G is CH Y is O or S; with the following provisos: 1) R 2) when Z is Z 3) when Z is Z 4) when Z is Z 5) when Z is Z 6) when Z is Z, r is 0, and R