Patent ID: 8883837
Filing Date: 2014-11-11
Classification: A61P,C07D

Abstract:
1. A compound having the formula an addition salt, quaternary amine, or a stereochemically isomeric form thereof, wherein G is a direct bond or C R wherein said pyridyl may optionally be substituted with 1 or where possible more, such as 2, 3, 4 or 5, substituents individually selected from the group of substituents consisting of halo, hydroxy, amino, cyano, carboxyl, C each n independently is 1, 2, 3 or 4; each t independently is 0, 1 or 2; Q is R R R one of R in case R in case R R R R R R R Ar Ar R R R Het is a heterocycle being selected from tetrahydrofuranyl, tetrahydrothienyl, pyrrolidinyl, pyrrolidinonyl, furanyl, thienyl, pyrrolyl, thiazolyl, oxazolyl, imidazolyl, isothiazolyl, pyrazolyl, isoxazolyl, oxadiazolyl, thiadiazolyl, piperidinyl, homopiperidinyl, piperazinyl, morpholinyl, pyridyl, pyrazinyl, pyridazinyl, pyrimidinyl, tetrahydroquinolinyl, quinolinyl, isoquinolinyl, benzodioxanyl, benzodioxolyl, indolinyl, or indolyl, each of said heterocycle may optionally be substituted with oxo, amino, Ar