Patent ID: 8992978
Filing Date: 2015-03-31
Classification: A61K,A61P,C12N

Abstract:
1. A bidirectionally transformable stem cell patch, said stem cell patch comprising: a) a porous biocompatible matrix having a thread or net structure and adult stem cells isolated from an exocrine gland tissue selected from the group consisting of pancreas, a sweat gland and a salivary gland of a donor organism, said thread or net structure configured for receiving the adult stem cells; and b) a supporting surface configured for placing said patch on a myocardial wound surface; wherein when said patch is placed between the myocardium freed from epicardium and the Latissimus Dorsi Muscle, said adult glandular stem cells contained within said patch contact on both sides with myocardium and Latissimus Dorsi Muscle tissue, wherein contact of cardiomyocytes or substances produced thereby induce differentiation of at least some of the adult glandular stem cells arranged in the patch on the side towards the myocardium wound surface into cardiomyocytes.