Patent ID: 8747347
Filing Date: 2014-06-10
Classification: A61B,A61M,B82Y,C12Q,G01N,Y10T

Abstract:
1. A method comprising embedding two or more laterally-mobile effector molecule types at least partially within a quasi-planar substrate of a device, transferring one or more cell types to the quasi-planar substrate of the device, interacting at least one of the two or more laterally-mobile effector molecule types with the one or more cell types, sensing at least one aspect of an interaction between the two or more laterally-mobile effector molecule types and the one or more cell types, controlling, in response to the sensing, initiation of modification of at least one of the two or more laterally-mobile effector molecule types and the quasi-planar substrate, and controlling, in response to the sensing, interaction of the at least one of the two or more laterally-mobile effector molecule types with the one or more cell types to activate, mature, differentiate, induce anergy in, load antigen to, electroporate, or transduce the one or more cell types.