Patent ID: 7470533
Filing Date: 2008-12-30
Classification: C12M,G01N,Y10T

Abstract:
1. A device for detecting cells on an electrode surface through measurement of impedance changes resulting from attachment of said cells to said electrode surface, which device comprises: a non-conductive substrate; a plurality of electrode arrays positioned on said substrate, wherein each electrode array comprises at least two electrode structures positioned on the same plane and having substantially the same surface area, and further wherein each electrode structure comprises at least two electrode elements and the electrode element width is between 1.5 and 15 times the width of the electrode gap between electrode elements of different electrode structures within said each electrode array, further wherein the electrode gap is at least 3 microns wide; a plurality of connection pads located on said substrate, wherein each connection pad is in electrical communication with at least one of said electrode structures; and wherein said device has a surface suitable for cell attachment or growth and said cell attachment or growth results in cellular contact with at least one of said electrode structures further resulting in a detectable change in AC electrical impedance between or among said electrode structures.