Patent ID: 8902420
Filing Date: 2014-12-02
Classification: G01N

Abstract:
1. A sensor chip for biomedical and micro-nano structured substances, comprising a plurality of metal nanoparticles and an anodized aluminum oxide film, wherein the anodized aluminum oxide film is made of a porous material with nano-pores and has a first surface, a second surface opposite to the first surface and a plurality of long tube shaped holes, therewith each of the holes having a first end and a second end, the first end having an opening at the first surface of the anodized aluminum oxide film, the second end of the hole being closed and located at the second surface of the anodized aluminum oxide film, the closed second end being covered by a barrier layer, and the plural metal nanoparticles being completely contained in the holes; the barrier layer covering the second end of the anodized aluminum oxide film has a thickness of 1 nm to 300 nm; and a Raman signal is detectable by Raman spectroscopy analysis when an analyte is provided in contact with the barrier layer at a second end of the sensor chip.