Patent ID: 6803363
Filing Date: 2004-10-12
Classification: A61K,A61M,A61P

Abstract:
A method of inhibiting or reducing infection sepsis within the abdomen and/or in and around an implanted peritoneal dialysis access catheter either after infusion of fresh peritoneal dialysis fluid or between infusions, method comprising the steps of:(i) removing substantially all existing peritoneal dialysis fluid from the lumen of the access catheter; (ii) replacing the removed peritoneal dialysis fluid in the lumen of the access catheter with a solution comprising taurolidine in a concentration of between about 0.2% to about 4% by weight and additionally comprising citric acid in a sufficient amount to bring the pH of the solution into a range from about 4 to about 7; and (iii) leaving the solution comprising taurolidine in the lumen of the access catheter for a specified time period.