Patent ID: 8996116
Filing Date: 2015-03-31
Classification: A61N

Abstract:
1. A method of enhancing spinal cord stimulation (SCS) therapy to treat chronic pain of a patient, the method comprising: electrically stimulating the neuronal cholinergic anti-inflammatory pathway for less than 10 minutes per day; treating the patient with spinal cord stimulation, wherein the step of electrically stimulating the neuronal cholinergic anti-inflammatory pathway comprises stimulating in an amount sufficient to disrupt or counter a release of inflammatory cytokines from glial cells; and timing the electrical stimulation of the neuronal cholinergic anti-inflammatory pathway and the spinal cord stimulation such that an effect on pain from the step of electrically stimulating the neuronal cholinergic anti-inflammatory pathway overlaps with an effect on pain from the step of treating the patient with spinal cord stimulation.