Patent ID: 6720434
Filing Date: 2004-04-13
Classification: B01J,C07B,C07D,C07F

Abstract:
A method of preparing chiral epoxides or chiral 1,2-diols which comprises: stereoselectively hydrolyzing racemic epoxides using a chiral catalyst of formula (1), wherein X1, X2, X3, X4, X5, X6, X7, and X8 represent independently hydrogen or C4-C10 alkyl;Y1 and Y2 represent independently hydrogen or C1-C5 alkyl; Z represents PF6, or BF4; and R1 and R2 independently represent hydrogen, C4-C10 alkyl, unsubstituted phenyl or C1-C4 alkyl substituted phenyl, where one of R1 and R2 should be a hydrogen atom, or R1 and R2 are bonded to be â€”(CH2)nâ€” (where n is an integer of 3 to 6) or â€”(CH2)mâ€”Qâ€”(CH2)mâ€” (where m is an integer of 1 to 2 and Q is an oxygen atom or NH).