Patent ID: 6692540
Filing Date: 2004-02-17
Classification: A61K,A61Q

Abstract:
A dyeing kit having at least two compartments, wherein a first compartment contains a dyeing composition and a second compartment contains an oxidizing composition comprising a non-enzymatic oxidizing agent,wherein said at least one dyeing composition comprises at least one oxidation base chosen from pyrazolo[1,5-a]pyrimidines of formula (I) and acid and base addition salts thereof: in which:R1, R2, R3 and R4, each of which may be identical or different, are chosen from a hydrogen atom; (C1-C4)alkyl radicals; aryl radicals; hydroxy(C1-C4)alkyl radicals; polyhydroxy(C2-C4)alkyl radicals; (C1-C4)alkoxy(C1-C4)alkyl radicals; amino(C1-C4)alkyl radicals in which the amine is optionally protected by an acetyl, an amido or a sulphonyl group; (C1-C4)alkylamino(C1-C4)alkyl radicals; di((C1-C4)alkyl)amino(C1-C4)alkyl radicals in which the dialkyls optionally form 5- or 6-member aliphatic or heterocyclic rings; hydroxy(C1-C4)alkylamino(C1-C4)alkyl radicals; and di(hydroxy(C1-C4)alkyl)amino(C1-C4)alkyl radicals; the X radicals, each of which may be identical or different, are chosen from a hydrogen atom; (C1-C4)alkyl radicals; aryl radicals; hydroxy(C1-C4)alkyl radicals; polyhydroxy(C2-C4)alkyl radicals; amino(C1-C4)alkyl radicals; (C1-C4)alkylamino(C1-C4)alkyl radicals; di((C1-C4)alkyl)amino(C1-C4)alkyl radicals in which the dialkyls optionally form 5- or 6-member aliphatic or heterocyclic rings; hydroxy(C1-C4)alkylamino(C1-C4)alkyl radicals; di(hydroxy(C1-C4)alkyl)amino(C1-C4)alkyl radicals; amino radicals; (C1-C4)alkylamino radicals; di((C1-C4)alkyl)amino radicals; halogen atoms; carboxylic acid groups; and sulphonic acid groups; i is 0, 1, 2 or 3; p is 0 or 1; q is 0 or 1; n is 0 or 1; with the proviso that:the sum p+q equals a value other than 0; when p+q equals 2, then n is 0, and the NR1R2 and NR3R4 groups occupy the (2,3), (5,6), (6,7), (3,5) or (3,7) positions; when p+q equals 1, then n is 1, and the NR1R2 group or NR3R4 group and the OH group occupy the (2,3), (5,6), (6,7), (3,5) or (3,7) positions; and at least one coupler chosen from substituted pyridines of formula (II) and acid addition salts thereof: in which:R5 is chosen from a hydrogen atom, a hydroxyl radical, an amino radical, a (C1-C4)alkoxy radicals, mono(C1-C4)alkylamino radicals, di(C1-C4)alkylamino radicals, monohydroxy(C1-C4)alkylamino radicals, polyhydroxy(C2-C4)alkylamino radicals, monohydroxy(C1-C4)alkoxy radicals, polyhydroxy(C2-C4)alkoxy radicals, and monohydroxy(C1-C4)alkoxy(C1-C4)alkoxy radicals; R6 is chosen from a hydrogen atom, a hydroxyl radical, an amino radical, and (C1-C4)alkyl radicals; R7 is chosen from a hydrogen atom and (C1-C4)alkyl radicals; R8 is chosen from a hydrogen atom, iodine, fluorine, and an amino radical; R9 is chosen from a hydrogen atom, a hydroxyl radical, an amino radical, (C1-C4)alkoxy radicals, monohydroxy(C1-C4)alkoxy radicals, and polyhydroxy(C2-C4)alkoxy radicals; wherein at least two of the radicals R5 to R9 are at least one substituent other than a hydrogen atom, wherein the at least one coupler is not 2,5-diaminopyridine; and wherein said composition lacks any enzymatic system capable of oxidizing any of the compounds of formula (I) and/or (II).