Patent ID: 6380263
Filing Date: 2002-04-30
Classification: A61K,A61Q

Abstract:
A regimen for promoting pigmentation of the skin and/or hair, comprising administering to an human in need of such treatment an effective tyrosinase activity-stimulating amount of at least one 6-substituted pyrimidine 3-oxide having the structural formula (I): in which R1 and R2, which may be identical or different, are each a hydrogen atom or a C1-C12 alkyl radical; and R3 and R4, which may be identical or different, are each a C1-C12 alkyl radical or, when taken together, form a heterocycle with the nitrogen atom from which they depend, with the proviso that, when R3 and R4, taken together, form a piperidino ring, then at least one of the radicals R1 or R2 must be other than a hydrogen atom.