Patent ID: 8846037
Filing Date: 2014-09-30
Classification: A61K,A61P,C07K

Abstract:
1. A method for treating or alleviating the symptoms of an IL-6 mediated disorder in a subject in need thereof, comprising administering to said subject an anti-IL-6 antibody or an antigen-binding portion thereof, wherein the antibody comprises a heavy chain and a light chain, and wherein (a) the heavy chain comprises the CDR1, CDR2 and CDR3 of the V (b) the heavy chain CDR1, CDR2, and CDR3 comprise the amino acid sequences of SEQ ID NOs: 5, 6, and 7, respectively, and the light chain CDR1, CDR2, and CDR3 comprise the amino acid sequences of SEQ ID NOs: 16, 17, and 18, respectively.