Patent ID: 9101304
Filing Date: 2015-08-11
Classification: A61B

Abstract:
1. A measuring system for measuring the concentration of substances or analytes in a body fluid or in a body tissue, comprising: a microdialysis probe comprising a multilumen tube and a microdialysis membrane, said tube having at least two longitudinally arranged inner bores, said bores extending from a proximal end of the tube to a distal end of the tube, at least two channels, one from each of said at least two bores to the outside of said tube, wherein said bores are blocked for passage of liquid distally of the respective channels, and a tubular membrane arranged circumferentially around the tube such as to cover the at least two channels, wherein said membrane is sealingly fastened to the tube thereby forming a space between the tube and the membrane, and wherein the probe is beth adapted to be placed in blood or in tissue, a flow through sensor for analysing a fluid having passed said microdialysis probe, a pump for pumping said fluid to and through said microdialysis probe and further to and through said sensor, and tubing connecting said pump to said microdialysis probe and said microdialysis probe to said sensor, said pump effecting a flow rate in said system in the interval 0.2-15 microliters per minute, wherein the sensor comprises a flow channel having a flow resistance or pressure drop adapted to the characteristics of the microdialysis membrane so as to eliminate, or at least substantially reduce, ultra filtering in the microdialysis membrane.