Patent ID: 7297692
Filing Date: 2007-11-20
Classification: A61K,A61P,C07D

Abstract:
1. A method for the treatment of a disease comprising administering to a patient in need of said treatment an effective amount of a compound of formula I: wherein R R or R R R or R R R R R R R or R R R or R n is 1 or 2; or an acid-addition salt, solvate or hydrate thereof; and wherein said disease is selected from the group consisting of obesity, type II diabetes, insulin resistance, hypertriglyceridemia, atherosclerosis, Cushing's syndrome, hypertension, pulmonary hypertension, cardiac insufficiency, myocardial infarction, coronary vasospasm, Raynaud's disease, unstable angina, percutaneous transluminal coronary angioplasty, cardiac ischemia, haemostasis disorders, migraine, cerebral vasospasm, cerebral hemorrhage, cerebral edema, depression, anxiety, stress, obsessive-compulsive disorder, panic attack, renal vasospasm, renal cortex necrosis, nephrogenic diabetes insipidus, gastric vasospasm, cirrhosis of the liver, ulcers, nausea and diabetic nephropathy.