Patent ID: 6423719
Filing Date: 2002-07-23
Classification: A61K,Y10S

Abstract:
A method of symptomatic treatment of benign prostatic hyperplasia in a subject, comprising: administering to a subject in need thereof, an effective amount of a compound of the formula: wherein R1 and R2, independently, are hydrogen or a C1-C6 linear or branched alkyl optionally interrupted by a carbonyl; R3 is a C1-C8 alkyl substituted by one or more moieties selected from the group consisting of hydroxyl, amino, mercapto, dioxolan, carbonyl and mixtures thereof; and R4 is hydrogen; a substituted or unsubstituted aromatic member selected from the group consisting of phenyl, biphenyl, benzyl, and furyl, wherein the substituent is selected from the group consisting of C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 alkoxy, C1-C4 alkylthio, halo and nitro; or a cycloalkyl selected from the group consisting of cyclohexyl and cyclopentyl; or a pharmaceutically acceptable acid addition salt thereof, in a unit dosage form.