Patent ID: 9029115
Filing Date: 2015-05-12
Classification: A61K,A61P,C12N

Abstract:
1. An isolated variant lipase which (a) has at least 90% identity to the sequence of amino acids 1-269 of SEQ ID NO: 2; (b) has lipase activity; and which, (c) as compared to the sequence of amino acids 1-269 of SEQ ID NO: 2, comprises substitutions N33Q+T231R+N233R and at least one substitution selected from the following: G38A,D,F,H,I,K,L,M,N,P,Q,S,T,W,Y; and G163A,C,D,E,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y.