Patent ID: 6368619
Filing Date: 2002-04-09
Classification: A61K,A61Q,C07K,C12N,Y10S

Abstract:
A process for the preparation of an essentially anhydrous optically clear hydrophobic preparation comprising a hydrophilic species in a hydrophobic solvent, the process comprising:(i) mixing a hydrophilic species with a dispersion consisting essentially of small unilamellar vesicles (SUVs) of an amphiphile in a hydrophilic solvent; (ii) removing the hydrophilic solvent to leave an array of amphiphile molecules with their hydrophilic head groups orientated towards the hydrophilic species and wherein there is no chemical interaction between the amphiphile and the hydrophilic species; and (iii) providing a hydrophobic solvent around the hydrophilic species/amphiphile array.