Patent ID: 7141580
Filing Date: 2006-11-28
Classification: A61K,A61P,C07D,Y02P

Abstract:
1. A method for the treatment of a disorder or condition in a mammalian subject including a human, wherein the disorder or condition is selected from pain, inflammation, osteoarthritis, and rheumatoid arthritis, said method comprising administering to a mammal in need of such treatment an effective amount of a compound of the following formula: or a pharmaceutically acceptable salt thereof, wherein one of Y R Q A is a 5–6 membered monocyclic aromatic ring optionally containing up to 3 heteroatoms selected from O, N and S, wherein said 5–6 membered monocyclic aromatic ring is optionally substituted with up to 3 substituents selected from halo, C B is halo-substituted C W is NH, N—C R Z is a 5–12 membered monocyclic or bicyclic aromatic ring optionally containing up to 3 heteroatoms selected from O, N and S, wherein said 5–12 membered monocyclic or bicyclic aromatic ring is optionally substituted with halo, C L is halo, C m is 0, 1 or 2; R R Q