Patent ID: 6495581
Filing Date: 2002-12-17
Classification: A61K,A61P,C07D

Abstract:
A compound represented by Formula (I): whereinR1 is an optionally substituted thiazolyl group; X is a bond, â€”COâ€”, â€”CH(OH)â€” or a group represented by â€”NR6â€” wherein R6 is a hydrogen atom or an optionally substituted alkyl group; n is an integer of 1 to 3; Y is an oxygen atom, a sulfur atom, â€”SOâ€”, â€”SO2â€” or a group represented by â€”NR7â€” wherein R7 is a hydrogen atom or an optionally substituted alkyl group; ring A is a benzene ring optionally having additional one to three substituents; p is an integer of 1 to 8; R2 is a hydrogen atom, an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; q is an integer of 0 to 6; m is 0 or 1; R3 is a hydroxy group; OR8, wherein R8 is an optionally substituted hydrocarbon group; or NR9R10, wherein R9 and R10 are the same or different groups which are selected from a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group and an optionally substituted acyl group or R9 and R10 combine together to form a ring; R4 and R5 are the same or different groups which are selected from a hydrogen atom and an optionally substituted hydrocarbon group wherein R4 may form a ring with R2; or a salt thereof.