Patent ID: 6248769
Filing Date: 2001-06-19
Classification: C07D

Abstract:
A compound of the formula: ##STR11##wherein:X.sub.1 and X.sub.2 may be the same or different and each is O or S;R.sub.1 and R.sub.2 may be the same or different and each are saturated or unsaturated straight-chain or branched alkyl groups containing from 1 to 12 carbon atoms, cycloalkyl and cycloalkyl-alkyl groups containing from 3 to 10 carbon atoms in the cycloalkyl moiety; or one of R.sub.1 and R.sub.2 are hydrogen and the other represents a hydrocarbon group as set forth above; said R.sub.1 and R.sub.2 are optionally substituted with a saturated or unsaturated straight-chain lower alkyl group containing from about 1 to about 6 carbon atoms, unsubstituted or substituted with one or more halogen atoms, hydroxyl groups, cyano groups, nitro groups, carboxyl groups, alkoxy groups, alkoxycarbonyl, carboxamido or substituted or unsubstituted amino groups; and at least one of R.sub.1 and R.sub.2 is a cycloalkyl moiety;R.sub.3 is hydrogen, halogen, or a saturated or unsaturated straight-chain or branched alkyl group containing from 1 to 12 carbon atoms, a cycloalkyl and cycloalkyl-alkyl groups containing from 3 to 7 carbon atoms in the cycloalkyl moiety;Z is a linkage selected from --CH.sub.2 --, --NH--, --CH.sub.2 O--, --CH.sub.2 CH.sub.2 --, --CH.sub.2 NH--, CH.sub.2 N(Me), NHCH.sub.2 --, --CH.sub.2 CONH--, --NHCH.sub.2 CO--, --CH.sub.2 CO--, --COCH.sub.2 --, --CH.sub.2 COCH.sub.2 --, --CH(CH.sub.3)--, --CH.dbd., and --HC.dbd.CH--, wherein the carbon and/or nitrogen atoms are unsubstituted or substituted with a lower alkyl, halogen, hydroxy or alkoxy group;R.sub.4 is a triazole, which is unsubstituted or substituted with one or more halogen atoms, C.sub.1-4 alkyl groups, hydroxyl groups, cyano groups, nitro groups, carboxyl groups, C.sub.1-4 alkyl esters, alkoxy groups, alkoxycarbonyl, amido, carboxamido, substituted or unsubstituted amino groups, cycloalkyl and cycloalkyl-alkyl groups containing from 3 to 10 carbon atoms in the cycloalkyl moiety, aryl or aralkyl groups containing from about 6 to about 10 carbon atoms, or heterocyclic groups containing nitrogen, oxygen or sulfur in the ring; said alkyl, cycloalkyl, cycloalkyl-alkyl, aryl, and aryl-alkyl groups being unsubstituted or substituted by halogen atoms, hydroxyl groups, cyano groups, carboxyl groups, C.sub.1-4 alkoxy groups, alkoxycarbonyl, carboxamnido or substituted or unsubstituted amino groups, or one or more lower alkyl groups having from 1 to 3 carbon atoms.