Patent ID: 8841275
Filing Date: 2014-09-23
Classification: A61K,A61P,C07H,Y02A

Abstract:
1. A compound represented by formula I: or a stereoisomer, a salt, a metabolite, or a deuteride thereof, wherein 1) R 2) R 3) R 4) Y is selected from the group consisting of 5) X is selected from the group consisting of 6) is a four- or five-membered ring selected from the group consisting of radicals a-o represented by the following structures where * represents the point of attachment to the 2′-carbon and where a) A is selected from the group consisting of b) D is selected from the group consisting of c) R 7) B is selected from among B2, and B3 represented by the following structures: where for B2, a) R where for B3 m is 0 or 1, and ---- is a single or double bond a) when m is 0, ----- is a double-bond and R b) when m is 1, ----- is a single-bond c) independent of the value of m, each bonding pair, W and where R