Patent ID: 7863454
Filing Date: 2011-01-04
Classification: A61P,C07B,C07D,C40B

Abstract:
1. A compound having the formula: or a pharmaceutically acceptable salt thereof, wherein: A is OR R (i) hydrogen, halogen, amino, and cyano; and (ii) C R R R (i) hydrogen, C R R (i) hydrogen, halogen, hydroxy, cyano, amino, C (ii) joined to R R R (i) hydrogen, halogen, hydroxy, C (ii) joined to R (iii) taken together with R R (i) absent, hydrogen, halogen, hydroxy, C (ii) joined to R (iii) taken together with R R R A X is a single bond, —CR R (i) hydrogen; or (ii) C Y is a single bond, —CR Z is independently selected at each occurrence from 3- to 7-membered carbocycles which is substituted with from 0 to 4 substituents independently selected from halogen, oxo, —COOH, hydroxy, amino, cyano, C R (i) hydrogen; and (ii) C R n is independently selected at each occurrence from 0, 1 and 2.