Patent ID: 6169080
Filing Date: 2001-01-02
Classification: A61P,C07D,C07F

Abstract:
A compound having the formula: ##STR10## wherein: R.sub.1 is formyl; acetyl; propionyl; butyryl; C.sub.2 -C.sub.8 alkenyl, or C.sub.2 -C.sub.8 alkynyl, optionally substituted by one or more halogen atoms or OR.sub.4 or lower alkyl for a corresponding hydrogen atom therein; arylalkenyl; arylalkynyl; heterocyclyl; --S(O)-- lower alkyl; -lower alkyl-P(O)R.sub.6 R.sub.7, or X-(C.sub.0 -C.sub.6 alkylene, lower alkenylene, or lower alkynylene)-SiR.sub.8 R.sub.9 R.sub.10 ; R.sub.2 is halo, lower alkyl, amino or nitro; R.sub.4 is hydrogen or lower alkyl; R.sub.5 is hydrogen or lower alkyl; R.sub.6 and R.sub.7 are each individually hydrogen or lower alkyl; R.sub.8, R.sub.9 and R.sub.10 are each individually hydrogen or lower alkyl; R.sub.11 is hydrogen, hydroxy, or acetoxy; and X is sulfur or X is absent; or a pharmaceutically acceptable salt thereof.