Patent ID: 6153627
Filing Date: 2000-11-28
Classification: C07D

Abstract:
A chroman of the formula ##STR8## wherein R.sup.1 is A,R.sup.2 is H or A,R.sup.1 and R.sup.2 together are also alkylene having 3-6 C atoms,R.sup.3 is OH or OAc,R.sup.4 is H,R.sup.3 and R.sup.4 together are also a bond,R.sup.5 is 1H-2-pyridon-1-yl, which is unsubstituted or monosubstituted or disubstituted by A, F, Cl, Br, I, OA, OAc, NO.sub.2, NH.sub.2, AcNH, HOOC and/or AOOC,R.sup.6 and R.sup.7 are each H, A, HO, AO, CHO, ACO, ACS, HOOC, AOOC, AO--CS, ACOO, A--CS--O, hydroxyalkyl having 1-6 C atoms, mercaptoalkyl having 1-6 C atoms, NO.sub.2, NH.sub.2, NHA, NA.sub.2, CN, F, Cl, Br, I, CF.sub.3, ASO, ASO.sub.2, AO--SO, AO--SO.sub.2, AcNH, AO--CO--NH, H.sub.2 NSO, HANSO, A.sub.2 NSO, H.sub.2 NSO.sub.2, HANSO.sub.2, A.sub.2 NSO.sub.2, H.sub.2 NCO, HANCO, A.sub.2 NCO, H.sub.2 NCS, HANCS, A.sub.2 NCS, ASONH, ASO.sub.2 NH, AOSONH, AOSO.sub.2 NH, ACO-alkyl, nitroalkyl, cyanoalkyl, A--C(.dbd.NOH) or A--C(.dbd.NNH.sub.2),R.sup.8 is HA is alkyl having 1-6 C atoms;alkyl is of 1-6 C atoms; andAc is alkanoyl having 1-8 C atoms or aroyl having 7-11 C atoms, or a physiologically acceptable salt thereof.