Patent ID: 7045621
Filing Date: 2006-05-16
Classification: A61P,C07C,C07D

Abstract:
1. A process for preparing a dibenzothiazepine compound of the following formula (5): in which each of R reacting a nitrobenzene compound of the following formula (1): in which each of R in which each of R in which each of R reducing the obtained 2-nitro-2′-carboxy-diphenylsulfide compound, in the presence of a compound selected from the group consisting of Raney-nickel, a ferrous salt, palladium/carbon, palladium/barium sulfate, a palladium compound and a platinum compound, to obtain a 2-amino-2′-carboxy-diphenylsulfide compound of the following formula (4): in which each of R subjecting the obtained 2-amino-2′-carboxy-diphenylsulfide compound to dehydration-condensation reaction.