Patent ID: 6605299
Filing Date: 2003-08-12
Classification: A61K,A61P,C07C,C07D,C07H,Y10T

Abstract:
A polypeptide composition having the general structure: whereinR1 is a hydrophilic polymer comprising a linkage for attachment to the dithiobenzyl moiety; R2 is selected from the group consisting of H, alkyl, and aryl; R3 is selected from the group consisting of O(C&boxH;O), S(C&boxH;O), and O(C&boxH;S); R5 is selected from the group consisting of H, alkyl and aryl; where orientation of CH2â€”R3 is selected from the ortho position and the para position; and n is at least 1; and a pharmaceutically-acceptable carrier.