Patent ID: 8385998
Filing Date: 2013-02-26
Classification: A61B,B29D,G02B,G02C

Abstract:
1. A contact lens with integrated biosensor, comprising: a) a contact lens having incorporated therein a biosensor for sensing bioanalytes present in tears; b) the biosensor including a physiologically compatible oxygen permeable substantially transparent and flexible substrate, and physiologically compatible porous nanostructures adhered on said physiologically compatible oxygen permeable and flexible substrate, a physiologically compatible fluorescent assay containing at least one physiologically compatible fluorescent dye encapsulated in said physiologically compatible porous nanostructures, said physiologically compatible fluorescent dye being selected to react or bind with a selected bioanalyte present in tears such that reacting or binding of the bioanalyte with the physiologically compatible fluorescent dye is responsively accompanied by a detectable change in optical properties of the physiologically compatible fluorescent dye indicative of the presence of the bioanalyte in tears when the contact lenses with integrated biosensor is on a person's eye and said physiologically compatible porous nanostructures having a porosity selected for collecting the tears; and c) said biosensor being located in said contact lens at a position off centre in the contact lens such as to not directly obstruct the vision of the person wearing the contact lens.