Patent ID: 6306179
Filing Date: 2001-10-23
Classification: C07C,Y02P

Abstract:
A 2-Hydroxyalkyl-para-phenylenediamine of the formula (I'), or an acid addition salt thereof: ##STR24##in which:n is an integer from 1 to 4 inclusive;R.sub.1, R.sub.2, R.sub.3 and R.sub.4, which are identical or different, are selected from a hydrogen atom and the following radicals:C.sub.1 -C.sub.6 alkyl,C.sub.1 -C.sub.6 monohydroxyalkyl,C.sub.2 -C.sub.6 polyhydroxyalkyl,C.sub.1 -C.sub.6 alkoxy-C.sub.1 -C.sub.6 alkyl,C.sub.1 -C.sub.6 aminoalkyl,mono- or dihydroxy(C.sub.1 -C.sub.6 alkyl)amino(C.sub.1 -C.sub.6 alkyl),(C.sub.1 -C.sub.6 mono- or dialkyl)amino(C.sub.1 -C.sub.6 alkyl),aminoalkyl whose amine is protected with a (C.sub.1 -C.sub.6 alkyl)carbonyl, carbamyl or (C.sub.1 -C.sub.6 alkyl)sulfonyl radical,C.sub.1 -C.sub.6 carboxyalkyl,C.sub.1 -C.sub.6 cyanoalkyl,C.sub.1 -C.sub.6 amidoalkyl,C.sub.1 -C.sub.6 trifluoroalkyl,C.sub.1 -C.sub.6 sulfonamidoalkyl,(C.sub.1 -C.sub.6 alkyl)carboxy(C.sub.1 -C.sub.6 alkyl),(C.sub.1 -C.sub.6 alkyl)sulfoxy(C.sub.1 -C.sub.6 alkyl),(C.sub.1 -C.sub.6 alkyl)sulfone(C.sub.1 -C.sub.6 alkyl),(C.sub.1 -C.sub.6 alkyl)keto(C.sub.1 -C.sub.6 alkyl),(C.sub.1 -C.sub.6 N-alkyl)amido(C.sub.1 -C.sub.6 alkyl) and(C.sub.1 -C.sub.6 N-alkyl)sulfonamido(C.sub.1 -C.sub.6 alkyl);R designates a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.6 alkyl radical or a group OZ or SZ in which Z designates a C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 monohydroxyalkyl or C.sub.2 -C.sub.6 polyhydroxyalkyl nradical;it being understoodthat at least one of the groups --NR.sub.1 R.sub.2 and --NR.sub.3 R.sub.4 designates an --NH.sub.2 group; andthat at least one of R, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 is different from a hydrogen atom; andthat when R.sub.1 and R.sub.2 simultaneously represent a hydrogen atom, n is equal to 1, R.sub.3 represents an ethyl group, and R.sub.4 represents methylcarboxyethyl, then R is not equal to a methyl group; orthat when R.sub.1, R.sub.2, and R.sub.3 simultaneously represent a hydrogen atom, n is equal to 1, and R.sub.4 represents an amidomethyl group, then R is not equal to a methyl group; orthat when R.sub.1 and R.sub.2 simultaneously represent a hydrogen atom, n is equal to 1, R.sub.3 is methyl acetate, and R.sub.4 represents an ethyl group, then R is not equal to a methyl group; orthat when R.sub.1, R.sub.2, and R.sub.3 simultaneously represent a hydrogen atom, n is equal to 1, and R.sub.4 represents methylcarboxyethyl, then R is not equal to a hydrogen atom; orthat when R.sub.1 and R.sub.2 simultaneously represent a hydrogen atom, n is equal to 1, R.sub.3 represents a .beta.-hydroxy ethyl group and R.sub.4 represents an amido methyl group, then R is not equal to hydrogen; orthat when R.sub.1 and R.sub.2 represent H, n is equal to 1, R.sub.3 represents ethyl, R.sub.4 represents C.sub.1 -C.sub.6 alkylcarboxymethyl, then R is not equal to H or CH.sub.3 ; orthat when R.sub.1 and R.sub.2 represent H, n is equal to 1, 2, 3 or 4, R.sub.3 represents H, (C.sub.1 -C.sub.6)alkyl, (C.sub.1 -C.sub.6)monohydroxyalkyl, (C.sub.2 -C.sub.6)polyhydroxyalkyl, (C.sub.1 -C.sub.6)alkoxy(C.sub.1 -C.sub.6)alkyl or an aminoalkyl whose amine is protected with a (C.sub.1 -C.sub.6)alkylcarbonyl or a methylsulphonyl radical, R.sub.4 represents H, (C.sub.1 -C.sub.6)alkyl, monohydroxy(C.sub.1 -C.sub.6)alkyl, (C.sub.2 -C.sub.6)polyhydroxyalkyl, (C.sub.1 -C.sub.6)alkoxy(C.sub.1 -C.sub.6)alkyl, C.sub.1 -C.sub.6 carboxyalkyl or aminoalkyl whose amine is protected with a (C.sub.1 -C.sub.6)alkylcarbonyl or a methylsuiphonyl radical, then R is not equal to H, halogen or C.sub.1 -C.sub.6 alkyl; orthat when R.sub.1 and R.sub.2 represent H, n is equal to 1, R.sub.3 represents H or (C.sub.1 -C.sub.6)alkyl, R.sub.4 represents H or (C.sub.1 -C.sub.6)alkyl, then R is not equal to H, (C.sub.1 -C.sub.6)alkoxy; orthat when R.sub.3 and R.sub.4 represent H, n is equal to 1, 2, 3 or 4, R.sub.1 and R.sub.2, independently of one another, represent H, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 monohydroxyalkyl, (C.sub.1 -C.sub.6)alkoxy(C.sub.1 -C.sub.6)alkyl, C.sub.2 -C.sub.6 polyhydroxyalkyl or an aminoalkyl whose amine is protected with a (C.sub.1 -C.sub.6)alkylcarbonyl or a methylsulphonyl radical, then R is not equal to H, halogen, C.sub.1 -C.sub.6 alkyl, or C.sub.1 -C.sub.6 alkoxy.