Patent ID: 9161996
Filing Date: 2015-10-20
Classification: A61K,B82Y,C23C,G01N,G01R,H01F

Abstract:
1. A gold coated super paramagnetic Iron oxide nano-particle (SPION) comprising; a core, and wherein the core includes a super paramagnetic Iron oxide nano-particle; a shell, and wherein the shell includes a jagged coating of gold; and a gap between the core and the shell, and wherein the gap is a polymeric gap, and wherein the gap is a non uniform gap, and wherein the gap includes a plurality of polymeric molecules, and wherein the plurality of polymeric molecules includes poly (2-vinyl pyridine), PL-PEG-COOH and Poly-L-histidine, and wherein the poly (2-vinyl pyridine) is a pH sensitive polymer, and wherein the poly (2-vinyl pyridine) controls a formation of jagged shaped gold surfaces, wherein poly (2-vinyl pyridine) has folded shape, and wherein PL-PEG-COOH has a stranded shape, wherein the gold coated SPIONS with a jagged surface conjugates with bio molecules to provide a nano probe for molecular diagnosis and cellular tracking, medical imaging and therapeutic applications, and molecular theragnosis, wherein therapeutic applications include a drug delivery and a simultaneous drug delivery and imaging application properties.