Patent ID: 7045140
Filing Date: 2006-05-16
Classification: A61K,A61P,C07F

Abstract:
1. A pharmaceutical composition, for delivery of carbon monoxide to a physiological target, comprising a metal carbonyl compound or pharmaceutically acceptable salt thereof and at least one pharmaceutically acceptable carrier, wherein the metal of said metal carbonyl is bound to at least one group other than CO which is a modulator group and said metalcarbonyl makes available CO suitable for physiological effect by at least one of the following means: 1) CO derived by dissociation of the metal carbonyl is present in the composition in dissolved form; 2) on contact with a solvent the metal carbonyl releases CO; 3) on contact with a tissue, organ or cell the metal carbonyl releases CO; 4) on irradiation the metal carbonyl releases CO; wherein said modulator group modulates the stability of the compound and/or the release of CO from the compound.