Patent ID: 6093743
Filing Date: 2000-07-25
Classification: A61K,A61P,Y02A,Y10S

Abstract:
A pharmaceutical composition comprising:i. a pharmaceutically acceptable carrier,ii. a compound having the structure (I) as follows:R.sub.1 R.sub.2 N--C(S)--S--S--(S)C--NR.sub.2 R.sub.1 (I)wherein:each of R.sub.1 and R.sub.2 is independently selected from a C.sub.1 up to C.sub.18 alkyl, substituted alkyl, a cycloalkyl, a substituted cycloalkyl, heterocyclic, a substituted heterocyclic, an alkenyl, a substituted alkenyl, an alkynyl, a substituted alkynyl, an aryl, a substituted aryl, an heteroaryl, a substituted heteroaryl, an alkylaryl, a substituted alkylaryl, an arylalkyl, and a substituted arylalkyl, orwherein R.sub.1 and R.sub.2 cooperate to form a 5-, 6- or 7-membered ring including N, R.sub.1 and R.sub.2 orR.sub.1 or R.sub.2 is a divalent moiety selected from the group consisting of an alkylene, a substituted alkylene, an oxyalkylene, a substituted oxyalkylene, an alkenylene, a substituted alkenylene, an arylene, a substituted arylene, an alkarylene, a substituted alkarylene, an aralkylene and a substituted aralkylene, wherein said divalent moiety serves as the same substituent for two dithiocarbamate structures, thereby linking said structures together so as to form a bis(dithiocarbamate), andiii. optionally, a biocompatible reducing agent to reduce the disulfide bond in the dithiocarbamate.