Patent ID: 6552022
Filing Date: 2003-04-22
Classification: A61P,C07D

Abstract:
A compound of formula (Ie) whereinR1 is selected from the following groups (i) aminocarbonyl, (ii) phenyl, optionally substituted by C1-6 alkyl, cyano, halogen, C1-6alkoxy, C1-3perfluoroalkyl, hydroxycarbonyl, C1-4alkoxycarbonyl, aminocarbonyl, methylenedioxy, nitro, C1-6 acyl, phenyl, or an optionally substituted oxadiazolyl, where optional substitution is effected by C1-4 alkyl or C1-3perfluoroalkyl, or (iii) an optionally substituted aromatic heterocyclyl having monocyclic radicals and fused polycyclic radicals, wherein said radicals contain a total of from 5-10 ring atoms and are selected from the group consisting of indolyl, pyrrolyl, thienyl, furanyl, imidazolyl, pyrazolyl, thiazolyl, pyridyl, and pyrazinyl, where optional substitution is effected by C1-4 alkyl; R2 represents phenyl, optionally substituted by one or two groups independently selected from halogen, C1-3perfluoroalkyl, C1-4alkyl and C1-4alkoxy groups; R3 represents hydrogen, halogen, C1-4alkyl or C1-4alkoxy; or a physiologically acceptable salt thereof.