Patent ID: 9200262
Filing Date: 2015-12-01
Classification: A61P,C07K,C12N,C12Q,G01N,Y10S

Abstract:
1. An antibody specifically binding to a sequence consisting of X 1 —P—H—X 2 —Y—X 3 —X 4 (SEQ ID NO: 28) contained in the antigen polypeptide expressed in a subject with ovarian cancer, the antigen polypeptide selected from the group consisting of: (a) a first polypeptide consisting of a first amino acid sequence consisting of at least 85% sequence identity with SEQ ID NO:2; (b) a second polypeptide encoded by a first polynucleotide consisting of a nucleotide sequence consisting of at least 85% sequence identity with SEQ ID NO: 1; and (c) a third polypeptide consisting of a first amino acid fragment encoded by a second polynucleotide as shown in SEQ ID NO: 4 or consisting of a second amino acid fragment as shown in SEQ ID NO: 3, provided that the sequence of the third polypeptide is included within (a) or (b), wherein X 1 is P; X 2 can be H, S, G or N; X 3 can be S, P, M, F, A or K and X 4 can be L, H, K, F, M, S or R.