Patent ID: 8236340
Filing Date: 2012-08-07
Classification: A61K,A61L

Abstract:
1. A medical device comprising a coating, wherein the coating comprises i) a non-volatile oil-based solvent, ii) a hydrophobic therapeutic agent selected from the group consisting of rapamycin, rapamycin analogs, ABT-578, everolimus, paclitaxel, dexamethasone, ceramides, dimethyl sphingosine, ether-linked diglycerides, ether-linked phosphatidic acids, sphinganines, steroids, taxol, taxol analogs, actinomycin D, prostaglandins, vitamin A, probucol, Batimastat, Statins, Trapidil, and Cytochalasin B, and iii) an amount of volatile solvent sufficient to decrease the viscosity of the non-volatile oil-based solvent, wherein the hydrophobic therapeutic agent is transferrable to a vessel upon contact therewith and is uniformly dispersed over the medical device within the non-volatile oil-based solvent.