Patent ID: 7700792
Filing Date: 2010-04-20
Classification: A61K,A61P,C07F,C07K,G01N

Abstract:
1. A method of screening for a therapeutic substance, which comprises contacting an LPA receptor with an optionally labeled highly active LPA compound represented by formula (I), (II) or (III): wherein R wherein arrowhead represents a binding site(s); Y represents carbonyl or methylene; p1 and q1 each independently represents an integer of 1 to 7; T represents wherein arrowhead represents a binding site(s), and wherein asymmetric carbon means R-configuration, S-configuration or a mixture thereof in any ratio; r represents an integer of 1 to 5 and when r represents 2 or more, plural r are the same or different, and wherein at least one of T in R wherein arrowhead represents a binding site(s), and wherein asymmetric carbon means R-configuration, S-configuration or a mixture thereof in any ratio, a salt thereof.