Patent ID: 8153110
Filing Date: 2012-04-10
Classification: A61K,A61P,C12N

Abstract:
1. A micellar polyion complex, which comprises: a block copolymer constituted by a polyethylene glycol portion and a polycation portion having a side chain whose terminus is a thiol group; wherein the block copolymer is represented by formula (1): wherein each of R L wherein wherein L k represents an integer between 100 and 500; m represents an integer between 0 and 499; n represents an integer between 1 and 500; and m+n=10 to 500; p represents an integer between 1 and 10; q represents an integer between 1 and 10; and r represents an integer between 1 and 10, wherein the symbol “/” in formula (1) indicates that the sequence order of respective monomer units described at the left and right sides thereof (the number of units: m+n) is arbitrarily determined and wherein n/(m+n) is greater than or equal to 0.65 and less than or equal to 1; and siRNA.