Patent ID: 9090883
Filing Date: 2015-07-28
Classification: C12N,C12Q,C12Y

Abstract:
1. A DNA polymerase having increased reverse transcriptase efficiency, compared with a control DNA polymerase under identical assay conditions, wherein the DNA polymerase has at least 90% amino acid sequence identity to SEQ ID NO:1 and the amino acid of the DNA polymerase corresponding to position 522 of SEQ ID NO:1 is G and the amino acid of the DNA polymerase corresponding to position 580 of SEQ ID NO:1 is G, and wherein the control DNA polymerase has the same amino acid sequence as the DNA polymerase except that the amino acid of the control DNA polymerase corresponding to position 522 of SEQ ID NO:1 is E and the amino acid corresponding to position 580 of SEQ ID NO:1 is D.