Patent ID: 9179869
Filing Date: 2015-11-10
Classification: A61B,A61L,B01D,B05D,C12Q,Y10T

Abstract:
1. A method for preparing an implantable membrane for an implantable glucose sensor, the method comprising: forming a composition comprising a dispersion of a first polymer within a matrix of a second polymer, wherein the first polymer comprises a hydrophilic segment, wherein the second polymer comprises polyurethaneurea; applying the composition to at least one of a substrate or a layer on the substrate to form a film thereon; and drying the film to form a membrane configured to cover at least a portion of an electrode of the implantable glucose sensor, whereby the membrane is configured to reduce passage of glucose therethrough, whereby the membrane is configured to change a ratio of oxygen to glucose from a concentration ratio in a body fluid to a new ratio in which there is a stoichiometric excess of oxygen in an enzyme layer of the implantable glucose sensor, whereby the membrane is configured to extend an upper limit of linearity of glucose measurement to a higher value than that which could be achieved without the membrane.