Patent ID: 6046220
Filing Date: 2000-04-04
Classification: A61P,C07C

Abstract:
A compound, having the general formula (I) below: ##STR7## in which: R.sub.1 is(i) the --CH.sub.3 radical(ii) the radical --CH.sub.2 --O--R.sub.6(iii) the radical --O--R.sub.6, or(iv) the radical --CO--R.sub.7R.sub.6 and R.sub.7 having the meanings given below,Ar is a radical selected from the group consisting of (a)-(e) below: ##STR8## R.sub.5 and R.sub.6 have the meanings given below, X is a radical of formula: ##STR9## R.sub.8 and R.sub.9 have the meanings given below, R.sub.2 and R.sub.3, taken together, form, with the adjacent aromatic ring, a 5- or 6-membered ring optionally substituted with one or more methyl groups,R.sub.4 and R.sub.5, which may be identical or different, are hydrogen atom, a halogen atom, a linear or a branched alkyl radical having from 1 to 20 carbon atoms or a radical --OR.sub.6,or R.sub.4 is a hydroxyl radical,R.sub.6 is a hydrogen atom, a lower alkyl radical or a radical --COR.sub.10R.sub.10 is defined below,R.sub.7 is selected from the following:(a) a hydrogen atom(b) a lower alkyl radical(c) a radical of formula: ##STR10## wherein R' and R"" are defined below, (d) a radical --OR.sub.11,(e) a radical --NHOR.sub.6,R.sub.11 is defined below,R.sub.8 and R.sub.9, are both a hydrogen atoms or one of them is a hydrogen atom and the other is a lower alkyl radical,R.sub.10 is a lower alkyl radical,R.sub.11 is a hydrogen atom, a linear or branched alkyl radical having from 1 to 20 carbon atoms, an alkenyl radical, a mono- or polyhydroxyalkyl radical, an optionally substituted aryl or aralkyl radical,R' and R"", which may be identical or different, are selected from a hydrogen atom, a lower alkyl radical, a mono- or polyhydroxyalkyl radical, an optionally substituted aryl radical, or alternatively, taken together, form a heterocycle, or a salt or optical or geometric isomer of said compound.