Patent ID: 6040175
Filing Date: 2000-03-21
Classification: C07K

Abstract:
A membrane preparation derived from a host cell, said host cell having incorporated expressibly therein a heterologous polynucleotide that encodes human GluR2B receptor selected from the group consisting of: (a) the sequence of amino acids 1-863 of SEQ ID NO:2, (b) a human GluR2B receptor variant having a sequence of amino acids 1-863 of SEQ ID NO:2 with the exception that there are from 1-32 conservative amino acid substitutions, (c) a membrane-bound fragment of the human GluR2B receptor of (a) or (b) comprising the extracellular N-terminal region that precedes TM-1, and (d) a membrane-bound fragment of the human GluR2B receptor of (a) comprising the extracellular C-terminal region that follows TM-4.