Patent ID: 8952055
Filing Date: 2015-02-10
Classification: A61K,A61P,C07D

Abstract:
1. A membrane fusion inhibitor that inhibits viral membrane fusion, the membrane fusion inhibitor comprising: first, second, third and fourth epigallocatechin gallate derivatives, wherein each of the first, second, third and fourth derivatives is represented by the following general chemical formula (1), an isomer thereof, or a salt thereof, where: each of R the acyl group is a linoleyl group or a linolenyl group, and may be substituted with one or more substituents selected from the group consisting of an alkyl group, an amino group, an alkylamino group, and a dialkylamino group, each of R 7 to R 11 , R 13 , R 15 , and R 16 is a hydrogen atom, and each of R 12 and R 14 is a hydrogen atom, sodium, or potassium and may be identical to or different form one another, wherein in the first epigallocatechin gallate derivative, R 1 is the acyl group; wherein in the second epigallocatechin gallate derivative, R 2 is the acyl group; wherein in the third epigallocatechin gallate derivative, R 5 is the acyl group; wherein in the fourth epigallocatechin gallate derivative, R 6 is the acyl group, wherein the first, second, third and fourth epigallocatechin gallate derivatives are different from one another, and wherein at least one of the first, second, third and fourth epigallocatechin gallate derivatives is a monoacylated epigallocatechin gallate derivative.