Patent ID: 6444820
Filing Date: 2002-09-03
Classification: A61P,C07D

Abstract:
The process for producing the compounds described and labeled in the specification as of formula 13G comprising the step of mixing the compounds described and labeled in the specification as of formula 12G with an acrylate ester in the presence of base; whereinR4 is optionally substituted C1-8 alkyl, C3-10 cycloalkyl, lower alkyl-C3-10 cycloalkyl, alkenyl, aryl, substituted aryl, alkylaryl, or substituted alkylaryl; R6 is optionally substituted C1-8 alkyl, aryl, substituted aryl, alkylaryl, substituted alkylaryl, C3-10 cycloalkyl, lower alkyl-C3-10 cycloalkyl, heteroaryl, or substituted heteroaryl; and R8 is optionally substituted C1-8 alkyl, C3-10 cycloalkyl, lower alkyl-C3-10 cycloalkyl, alkenyl, aryl, substituted aryl, alkylaryl, or substituted alkylaryl.