Patent ID: 7544348
Filing Date: 2009-06-09
Classification: A61K,Y10S

Abstract:
1. A pseudoplastic liquid composition for treating or inhibiting an oral mucocutaneous disorder, said pseudoplastic liquid composition having a zero shear viscosity at 37±1 degrees Celsius of 100-20,000 centipoise, comprising 0.1 to 2.0 wt/wt% of one or more mucoadhesives, wherein the mucoadhesive(s) is/are selected from the group consisting of polyvinylpyrrolidone, carboxymethylcellulose, dextran sulfate, hydroxyalkylcellulose, dermatan sulfate, a water-soluble vinyl polymer, chitosan, guar gum, xanthan gum, tragacanth gum, pectin and polyacrylic acid; wherein said pseudoplastic viscous liquid composition, when administered to an oral mucosa: 1) remains liquid when shear is applied due to swishing the liquid in the mouth; and 2) attaches to and coats the oral mucosa upon discontinuance of said shear.