Patent ID: 6649769
Filing Date: 2003-11-18
Classification: C07H,C09B,G01N

Abstract:
An energy-transfer dye comprising:a donor dye capable of absorbing light at a first wavelength and emitting excitation energy in response thereto; an acceptor dye capable of absorbing the excitation energy emitted by the donor dye and fluorescing at a second wavelength in response; and a linker for linking the donor dye and the acceptor dye; wherein at least one of the donor dye and acceptor dye is an atropisomerically enriched xanthene compound having the structure: Z1 is OH, NH2, NHR, or NR2, wherein each R is independently hydrogen, C1-C12 alkyl, phenyl, benzyl, aryl, heterocycle, or a linking moiety; Z2 is O, +NHR, +NR2, wherein each R is independently hydrogen, C1-C12 alkyl, phenyl, benzyl, aryl, heterocycle, or a linking moiety; X is carboxylate or sulfonate; and said structure comprises aryl-substituted forms thereof.