Patent ID: 8715921
Filing Date: 2014-05-06
Classification: C12Q,G01N

Abstract:
1. A diagnostic method for asymptomatic cerebral infarction, comprising: (a) obtaining at least one biological sample from a subject; (b) measuring biogenic polyamine content in the biological sample; wherein a measure of biogenic polyamine content is at least two measures selected from a measure of polyamine content in the biological sample; a measure of aldehyde compound content formed from the polyamine in the biological sample; a measure of polyamine oxidase activity in the biological sample; and a measure of polyamine oxidase protein content in the biological sample; and (c) comparing the biogenic polyamine content of the biological sample in (b) to polyamine content of a biological sample of a healthy subject, wherein a difference in measured value of the subject in (a) compared to a measured value of a healthy subject is indicative of an asymptomatic cerebral infarction.