Patent ID: 6207690
Filing Date: 2001-03-27
Classification: A61K,A61L,A61P,G10K

Abstract:
A method for treating a tumor in a subject comprising administering a therapeutically effective amount of a compound of Formula I: ##STR23##wherein R.sup.1 and R.sup.2 are the same or different and each represents a hydrogen atom or a C.sub.1 -C.sub.5 alkyl group;R.sup.3 represents a hydrogen atom, a C.sub.1 -C.sub.6 aliphatic acyl group, an alicyclic acyl group, an aromatic acyl group, a heterocyclic acyl group, an araliphatic acyl group, a (C.sub.1 -C.sub.6 alkoxy)carbonyl group, or an aralkyloxycarbonyl group;R.sup.4 and R.sup.5 are the same or different and each represents a hydrogen atom, a C.sub.1 -C.sub.5 alkyl group or a C.sub.1 -C.sub.5 alkoxy group, or R.sup.4 and R.sup.5 together represent a C.sub.1 -C.sub.4 alkylenedioxy group;n is 1, 2 or 3;W represents the --CH.sub.2 --,>CO, or CH--OR.sup.6 group (in which R.sup.6 represents any one of the atoms or groups defined for R.sup.3 and may be the same as or different from R.sup.3); andY and Z are the same or different and each represents an oxygen atom or an imino (.dbd.NH) group; and pharmaceutically acceptable salts thereof.