Patent ID: 7732151
Filing Date: 2010-06-08
Classification: A61P,C07K,C12Q,G01N

Abstract:
1. A method for determining the ability of a first polypeptide to modify the phosphorylation status of a second, biotinylated polypeptide, the method comprising the steps of a. contacting the first polypeptide with the second polypeptide in a suitable reaction mixture; b. contacting the reaction mixture with a means which is coupled to a carrier and is able to bind to the second polypeptide; and c. determining the phosphorylation state of the second polypeptide, wherein the carrier comprises a first carrier and a second carrier, wherein the first carrier comprises a first signal generator and the second carrier comprises a second signal generator, wherein the first carrier is coupled to the means and the second carrier is coupled to the second polypeptide.