Patent ID: 6867199
Filing Date: 2005-03-15
Classification: A61K,C07H,Y10S

Abstract:
1. A compound of Formula II, or the pharmaceutically acceptable non-toxic esters, amides, ureas, carbamates, ethers, acetals, ketals and/or salts thereof: wherein: D=O or CH X is oxygen, methylene, dihalomethylene, or imido; n=0, 1 or 2; m=0, 1 or 2; n+m=0, 1, 2, 3 or 4; Z=OH or H; Z′=OH or H; Y=OH or H; Y′=OH or H; and B and B′ are each independently a purine residue or a pyrimidine residue, as defined in Formula IIa′ or IIb, linked through the 9- or 1-position, respectively; and provided that at least one of B and B′ is an 8-azapurine; R R R R R J is nitrogen or carbon; provided that when J is nitrogen, R wherein: R R R R R R R wherein the alkyls are straight-chain, branched or cyclic; wherein the alkyl and aryl groups are optionally substituted with lower alkyl, aryl, amino, mono- or dialkylamino, NO