Patent ID: 8957088
Filing Date: 2015-02-17
Classification: A61P,C07D

Abstract:
1. A method of treating a disease selected from the group consisting of allergic rhinitis, asthma, COPD, adult respiratory distress syndrome, bronchitis, B-cell lymphoma, dermatitis and contact dermatitis, allergic dermatitis, allergic rhinoconjunctivitis, rheumatoid arthritis, idiopathic thrombocytopenic purpura, allergic conjunctivitis, lupus erythematodes, capsule cell lymphoma and multiple sclerosis comprising administering a therapeutically effective amount of a compound of formula 1, to a patient in need thereof, wherein: R or R C five- to ten-membered, mono- or bicyclic heteroaryl with 1-3 heteroatoms selected independently of one another from among N, O and S; where this heteroaryl is linked to the structure according to formula 1 via either a C atom or an N atom, three-to ten-membered, mono- or bicyclic, saturated or partly saturated heterocyclic group with 1-3 heteroatoms selected independently of one another from among N, O and S, while this heterocyclic group is linked to the structure according to formula 1 via either a C atom or an N atom, and 5-to 11-membered spiro group which may optionally contain 1, 2 or 3 heteroatoms selected independently of one another from among N, O and S, while this spiro group is linked to the structure according to formula 1 via either a C atom or an N atom, while this group B may optionally be substituted by one or more groups selected independently of one another from among H, halogen, —C R or a group selected from among —C while this group may optionally be substituted by one or more groups selected independently of one another from among H, —OH, -oxo, —COOH, -halogen, —C wherein (Het) denotes a three-to ten-membered, saturated or partly saturated, mono- or bicyclic heterocyclic group, optionally substituted by 1-3 groups selected from C and (Hetaryl) denotes a five- to ten-membered, mono- or bicyclic heteroaryl, optionally substituted by 1, 2 or 3 groups selected from C m=0 or 1 R R