Patent ID: 6350472
Filing Date: 2002-02-26
Classification: A61K,A61P

Abstract:
A method of treating an HIV-1 infection in a mammal by administering percutaneously, through a topical application to the skin, a therapeutically effective amount of a porcine liver extract in a colloidal dispersion through a composition comprised of:a transdermal delivery system comprising a colloidal dispersion containing a lecithin and a copolymer gel; and a therapeutically effective amount of a porcine liver extract in said colloidal dispersion, wherein said porcine liver extract is at a concentration of about 50 mg/ml in said dispersion, and further comprises a heterogeneous polypeptide mixture that is heat stable, insoluble in acetone, soluble in water and is also referred to as Kutapressin, that has been concentrated to substantially remove liquid and then emulsified to form said dispersion, so that said porcine liver extract is present in said transdermal delivery system in concentrated form as a dispersion, and substantially at least 400 mg of the porcine liver extract thereby is topically administered daily.