Patent ID: 8268835
Filing Date: 2012-09-18
Classification: A61P,C07D

Abstract:
1. A compound of formula (4a), wherein: R R R each R each R each R n is 0, 1, 2, 3, 4, or 5; and t is 0, 1, 2, 3, 4, or 5; or a pharmaceutically acceptable salt thereof, with the proviso that the compound of formula (4a) is not 6-cyclopentyl-3-[(5,7-dimethyl[1,2,4]triazolo[1,5-a ]pyrimidin-2-yl)methyl]-6-[2-(2-ethylpyridin-4-yl)ethyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one, 3-[(6-chloro[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-6-cyclopentyl-6-[2-(2-ethylpyridin-4-yl)ethyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one, or 6-cyclopentyl-3-[(5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-6-[2-(5-ethylpyridin-3-yl)ethyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one.