Patent ID: 6541488
Filing Date: 2003-04-01
Classification: A61K,A61P

Abstract:
A method for the treatment or prophylaxis of thromboembolic arterial diseases which comprises administering to a patient in need of such treatment a synergistic effective amounts of methyl O-(2-deoxy-2-sulphoamino-6-O-sulfo-&agr;-D-glucopyranosyl)-(1â†’4)-O-(&bgr;-D-glucopyranosyluronic acid)-(1â†’4)-O-(2-deoxy-2-sulphoamino-3 ,6-di-O-sulpho-&agr;-D-glucopyranosyl-(1â†’4)-O-(2-O-sulpho-&agr;-L-idopyranosyluronic acid)-(1â†’4)-2-deoxy-2-sulphoamino-6-O-sulpho-&agr;-D-glucopyranoside having, in anionic form, the formula or a pharmaceutically acceptable salt thereof in combination with ethyl N-(1-ethoxycarbonylmethylpiperidin-4-yl)-N-(4-[4-((N-ethoxycarbonylimino)(amino)methyl)phenyl]-thiazol-2-yl)-3-aminopropionate having the formula or a pharmaceutically acceptable, salt thereof.