Patent ID: 8642617
Filing Date: 2014-02-04
Classification: A61P,C07D

Abstract:
1. A compound of the formula (I) wherein: one atom among Y, Z, W is a nitrogen atom and the other atoms from Y, Z and W, and also X, are a carbon atom substituted by a substituent selected from: A is: aryl, arylalkyl, or heteroaryl with one or more heteroatoms selected from N,O and S; each of these groups optionally substituted by one or more substituents selected from T; R1 is: alkyl, alkoxyalkyl, cycloalkyl, cycloalkylalkyl, heterocycloalkyloxyalkyl, heterocycloalkylalkoxyalkyl, heterocycloalkylthioalkyl, heterocycloalkylalkylthioalkyl, aryl, heteroaryl, arylalkyl, or heteroarylalkyl; each of these groups optionally substituted by one or more substituents selected from T; T is: hydroxy, thio, halogen, trifluoromethoxy, trifluoromethyl, carboxy, carboxymethyl, carboxyethyl, alkyl, cycloalkyl, alkoxy, alkylamino, aryl, arylsulfonylalkyl, aryloxy, arylalkoxy, azido, nitro, guanidino, phosphono, oxo, carbamoyl, alkylsulfonyl, alkylsulfinyl, alkylthio, or SF or two T groups together form methylenedioxy; or a racemic, tautomer, enantiomer, diastereomer or epimer form thereof, or mixtures thereof, or a pharmaceutically acceptable salt thereof.