Patent ID: 9220750
Filing Date: 2015-12-29
Classification: A61K,A61P,G01N

Abstract:
1. A method for optimizing cellular uptake of a pharmaceutical substance and/or formulation, said method comprising administering to a subject a pharmaceutical composition comprising: a) an antisecretory factor (AF) protein; a derivative, homologue and/or fragment thereof having AF activity; and/or a pharmaceutically active salt thereof in an amount sufficient to induce normalization and/or reduction of the intracellular pressure in a pathological cell for optimizing cellular uptake of a further pharmaceutical substance, and b) a further pharmaceutical substance selected from the group consisting of anticancer drugs, cytostaticas, antimicrobial substances, antibiotic substances, antiviral substances, antibodies, drugs targeting a posttraumatic injury, drugs targeting neurodegeneration, drugs targeting a parasite, and drugs targeting an inflammatory condition.