Patent ID: 6979747
Filing Date: 2005-12-27
Classification: A61K,A61P,A61Q,C07C

Abstract:
1. A process for the preparation of a compound of general formula: in which: the dimers formed by a disulfide bridge from one and/or other of the two sulfur atoms of the compounds of general formula I composed of the R″ radicals or of the R′CO— radicals of the two molecules, and the corresponding thiazolidine forms; said process comprising the following stages: a) protection of the N-acyl-L-cysteine to provide the N-acyl-S-trityl-L-cysteine compound; then b) coupling of the protected N-acyl-S-trityl-L-cysteine with the S-acetylcysteamine hydrochloride to provide the N-(N-acyl-S-trityl-L-cysteinyl)-S-acylcysteamine compound.