Patent ID: 7846474
Filing Date: 2010-12-07
Classification: A61K,A61P

Abstract:
1. A process for the treatment of osteogenesis imperfecta in a patient in need thereof comprising: performing a bone volumetric mineral density test on said patient and upon diagnosing the patient is experiencing osteogenesis imperfecta administering a sufficient amount of a preparation of at least one bisphosphonate to the patient until a volumetric mineral density of the cortical tissue is within a normal range (means±1 SD) of the volumetric mineral density of a person of the same age of the patient; monitoring the bone volumetric mineral density of the patient and interrupting the administration of the preparation of bisphosphonate during the time in which the volumetric mineral density does not drop lower than 5% from the normal range (means±1 SD) of the volumetric mineral density of a person of the same age of the patient; performing a bone volumetric mineral density test on said patient; resuming the administration of bisphosphonate when the volumetric mineral density falls by 5% of the normal range (means±1 SD) of the volumetric mineral density of a person of the same age of the patient, until the normal range (means±1 SD) of the volumetric mineral density of the person of the same age of the patient is reached again; and repeating these steps.