Patent ID: 6498155
Filing Date: 2002-12-24
Classification: A61K,A61P

Abstract:
A method of treating thrombocytopenia in a mammal, including a human, in need thereof which comprises administering to such mammal a therapeutically effective amount of a compound of Formula (I)Zâ€”Râ€”Aâ€”Râ€²â€”Yâ€ƒâ€ƒ(I) in which Z and Y are independently cyclic polyamine moieties having from 9 to 32 ring members and from 3 to 8 amine nitrogens in the ring spaced by 2 or more carbon atoms from each other;A is an aromatic or heteroaromatic moiety; and R and Râ€² are each a substituted or unsubstituted alkylene chain or heteroatom-containing chain which spaces the cyclic polyamines and the moiety A, or an acid addition salt or metal complex thereof.