Patent ID: 6251870
Filing Date: 2001-06-26
Classification: A61K,A61P

Abstract:
A pharmaceutical composition for treating cancers or tumors susceptible to treatment comprising:a safe and effective amount of a chemotherapeutic agent wherein said chemotherapeutic agent is selected from the group consisting of Methotrexate, Fluorouracil, Fluorodeoxyuridine, N.sup.10 -propargyl-5,8-dideazafolic acid, Azacitidine, Cytarabine, Floxuridine, Mercaptopurine, 6-Thioguanine, Pentostatin, Fludarabine, Tamoxifen and Busulfan; anda safe and enhanced amount of an N-chlorophenylcarbamate or N-chlorophenylthiocarbamate of the formula: ##STR3##whereinn is from 1 to 3;X is selected from the group consisting oxygen and sulfur; andR is selected from the group consisting of hydrogen, lower alkyl, lower alkenyl, cyclohexyl, phenyl, and phenalkyl of up to 8 carbon atoms;or a pharmaceutically acceptable inorganic or organic acid salt thereof.