Patent ID: 6617438
Filing Date: 2003-09-09
Classification: A61K,C07H,C12N,C12P,C12Y

Abstract:
An enzymatic nucleic acid molecule having formula III namely: wherein each X, Y, and Z represents independently a nucleotide which may be the same or different; q is an integer selected from the group consisting of 4, 5, 6, 7, 8, 9, 10, 11, 12, and 15; n is an integer ranging from 1 to 10; o is an integer ranging from 3-100; Zâ€² is a nucleotide complementary to Z; each X(q) and X(o) are oligonucleotides which are of sufficient length to stably interact independently with a target nucleic acid sequence; W is a linker ranging from 2 to 70 nucleotides in length or may be a non-nucleotide linker; A, U, G, and C represent nucleotides; C is 2â€²-amino; and_represents a chemical bond or chemical linkage.