Patent ID: 6387938
Filing Date: 2002-05-14
Classification: C07D

Abstract:
A compound represented by the following formula (I) (wherein R1 represents hydrogen atom or a straight- or branched-chain alkyl group having 1 to 4 carbon atoms, R2 represents cyano group, hydroxymethyl group, 2-(2-imidazolyl)ethenyl group, a phenyl group substituted by one or two â€”COOR3 groups, or a group â€”COOR3 or â€”CONR4R5, R3 represents hydrogen atom or a straight- or branched-chain alkyl group having 1 to 4 carbon atoms, each of R4 and R5 represents hydrogen atom, an alkyl group having 1 or 2 carbon atoms or a group â€”CH2COOR6 or â€”CH(CH2Ph)COOR6, wherein R4 and R5 may be the same or different from each other but, when one of R4 and R5 is a group â€”CH2COOR6 or â€”CH(CH2Ph)COOR6, the other one is hydrogen atom, A represents any one of groups selected from the class consisting of â€”COâ€”, â€”CH(OR8)â€”, â€”CH2Oâ€”, â€”CH(NHR9)CH2â€”, â€”CH&boxH;CHâ€” and â€”CH2CH2â€”, W represents a group â€”CH2â€” or a single bond, Q represents a phenyl group which may be substituted by one hydroxyl group, n is from 0 to 2, R6 represents a straight- or branched-chain alkyl group having 1 to 4 carbon atoms, R7 represents hydrogen atom, hydroxyl group, a halogen atom or a straight- or branched-chain alkoxyl group having 1 to 4 carbon atoms, R8 represents hydrogen atom or acetyl group and R9 represents hydrogen atom, acetyl group, phenylsulfonyl group or a benzoyl group which may be substituted by one methoxy group) or a salt thereof.