Patent ID: 7749766
Filing Date: 2010-07-06
Classification: C12Q,Y10T

Abstract:
1. A bilirubin sensor comprising: a working electrode with a first chemical matrix disposed thereon, the first chemical matrix containing a binder, wherein the first chemical matrix is capable of oxidizing all oxidizable species in a fluid sample; a substrate electrode with a second chemical matrix disposed thereon, the second chemical matrix containing a binder and a chemical agent that consumes bilirubin, wherein the second chemical matrix is capable of oxidizing all oxidizable species in the fluid sample except bilirubin; a reference electrode; a sample chamber containing the working electrode, the substrate electrode and the reference electrode; means for applying a potential between the reference electrode and the working electrode to obtain a first current; means for applying a potential between the reference electrode and the substrate electrode to obtain a second current; means for correlating the first current to a concentration of all oxidizable species in the fluid sample and for correlating the second current to a concentration of all oxidizable species in the fluid sample except bilirubin; means for subtracting the second current from the first current to obtain a current difference; and means for correlating the current difference to a concentration of bilirubin in the fluid sample.