Patent ID: 7112568
Filing Date: 2006-09-26
Classification: A61K,A61P,C07K

Abstract:
1. An anti-allergic agent, comprising a complex molecule having at least a first segment competent for importation of said molecule into mast cells, and a second segment for having an anti-allergic effect with said mast cells, said first segment being a peptide and joined to said second segment through a linker, said linker providing a bend or turn at or near the junction between the two segments, with the proviso that the first segment is other than the peptide AAVALLPAVLLALLAP (SEQ ID NO: 27), when the second segment is the anti-allergic decapeptide of the C-terminal end of Gαi3 (SEQ ID NO: 1) or Gαt (SEQ ID NO: 2), wherein said first segment comprises 10-50 amino acids having a hydrophobic, lipid soluble portion.