Patent ID: 6274174
Filing Date: 2001-08-14
Classification: A61K,C08B,C08L

Abstract:
A process for preparing aggregates of spherical microparticles of a multivalent metal alginate, which comprises the steps of:adding an aqueous sodium alginate solution and/or an aqueous alginic acid solution to a non-aqueous solvent comprising a polyhydric alcohol fatty acid ester, and then adding an emulsifying agent to the formed mixture so as to cause emulsion dispersion, thereby forming a water-in-oil (W/O) type emulsion;adding an aqueous solution of a multivalent metal salt to the emulsion to form spherical microparticles of the multivalent metal alginate; andspray-drying a suspension of the spherical microparticles in water, thereby forming aggregates of the spherical microparticles.