Patent ID: 6579880
Filing Date: 2003-06-17
Classification: C07D

Abstract:
A compound of Formula (I) or (II), whereinR is one or two independent members selected from hydrogen, halogen, C1-6 alkyl, C1-6 alkoxy, alkoxycarbonyl, aryl, aryloxy, hydroxy, nitro, sulfonylamino, trifluoromethyl, and cyano, and methylenedioxy and ethylenedioxy where two adjacent R members form these dioxy rings; X is nitrogen or CR1 wherein R1 is selected from hydrogen, alkyl, aryl, halogen, CH2OH, carbomethoxy, and carboethoxy; Y is CR or nitrogen, provided that when X is nitrogen then Y is nitrogen; L is selected from oxygen, sulfur, â€”N(R2)â€”, â€”C(O)NR2â€”, â€”R2NC(O)â€”, â€”C(O)Oâ€”, and â€”OC(O)â€”, wherein R2 is hydrogen or C1-6 alkyl; and Z is a piperazino ring; Alk is a branched or unbranched alkyl group; n is an integer from 0-6 representing the number of carbons in the alkylene group, with the proviso that when L is oxygen, sulfur, or nitrogen, n is an integer from 2-6; or an optical isomer, enantiomer, diastereomer, racemate or racemic mixture thereof, or a pharmaceutically acceptable salt thereof.