Patent ID: 6180628
Filing Date: 2001-01-30
Classification: A61P,C07D

Abstract:
A method of preventing influenza virus infection in a host susceptible to said infection, said method comprising administering to said host a prophylactically effective amount of a compound having the formula: ##STR15##wherein R.sub.1 represents CH.sub.3 R.sub.2 represents ##STR16##V represents a substituent selected from the group consisting of COOR.sub.3, SO.sub.2 NR.sub.4 R.sub.5 and ##STR17##W represents a substituent selected from the group consisting of H, CH.sub.3 or Cl; X, Y and Z represent H; Q and the carbon atoms to which it is attached represent a heterocyclic ring selected from the group consisting of ##STR18##wherein the bond between the positions a, b of said heterocyclic ring forms a common bond with aromatic ring (Ar); R.sub.3 represents H or an alkyl (C.sub.1 -C.sub.6) substituent; R.sub.4 and R.sub.5 are the same or different and represent H, acetyl, methyl, substituted or unsubstituted phenyl, or substituted or unsubstituted pyridyl, said phenyl and said pyridyl substituents being selected from those consisting of alkyl, alkoxy, hydroxy, carboxy and halogen groups, and the isomers and pharmaceutically acceptable salts of said compound.