Patent ID: 6593312
Filing Date: 2003-07-15
Classification: A61P,C07C,C07D

Abstract:
A compound selected from those of formula (I): wherein: represents a saturated carbon ring having from 4 to 8 ring members, optionally substituted by one or more linear or branched (C1-C6)alkyl groups,R1 and R4, which may be identical or different, each represents hydrogen or linear or branched (C1-C6)acyl, R2 and R3, which may be identical or different, each represents hydrogen or linear or branched (C1-C6)alkyl, R5 and R6, which may be identical or different, each represents hydrogen or linear or branched (C1-C6)alkyl, â€ƒor R5 and R6 together, with the nitrogen atom carrying them, form a nitrogen-containing heterocycle optionally substituted by one or more identical or different groups selected from cyano, CO2R7 (wherein R7 represents hydrogen or linear or branched (C1-C6)alkyl), COR7 (wherein R7 is as defined hereinbefore), nitro, CONR8aR8b (wherein R8a and R8b, which may be identical or different, each represents hydrogen or linear or branched (C1-C6)alkyl or R8a and R8b together form a nitrogen-containing heterocycle), S(O)nR9 (wherein n represents 1, 2 or 3, and R9 represents hydrogen, linear or branched (C1-C6)-alkyl or aryl) and PO3R10aR10b â€ƒwherein R10a and R10b, which may be identical or different, each represents hydrogen or linear or branched (C1-C6)-alkyl, a stereoisomer thereof, or an addition salt thereof with a pharmaceutically acceptable acid, wherein a nitrogen-containing heterocycle is an optionally bridged, saturated mono- or bi-cyclic group having from 5 to 12 ring members and containing one, two or three hetero atoms, one of those hetero atoms being nitrogen and the additional hetero atom or atoms optionally present being selected from oxygen, nitrogen and sulphur, and an aryl group is a phenyl, biphenyl, naphthyl or tetrahydronaphthyl, each of those groups optionally being substituted by one or more identical or different atoms or groups selected from halogen, linear or branched (C1-C6)alkyl, hydroxy, linear or branched (C1-C6)alkoxy, linear or branched (C1-C6)polyhaloalkyl, nitro and (C1-C2)alkylenedioxy.