Patent ID: 8551072
Filing Date: 2013-10-08
Classification: A61L

Abstract:
1. A method for modulating remodeling of an infarct region of a myocardium, the method comprising: identifying an infarct region within a ventricle of the myocardium; infusing microparticles into a coronary artery to said infarct region with a catheter assembly, the catheter assembly comprising at least one elongate catheter shaft having an inner surface defining a lumen, said microparticles are covalently bonded to the inner surface through a linkage which is cleavable by enzymes or in the presence of water, said microparticles comprising at least one therapeutic agent effective for modulating remodeling of the infarct region, said microparticles having a mixed diameter range of about 1 micron to about 45 microns, and perfusing a liquid comprising enzymes or water through said lumen of said at least one catheter shaft.