Patent ID: 8321008
Filing Date: 2012-11-27
Classification: A61K,A61N

Abstract:
1. An electrokinetic delivery system for administration of a medicament to a treatment site on a human individual, the delivery system comprising: a cartridge applicator device shaped in part to conform to at least a portion of the undersurface of a digit of the individual and including a retainer for releasably securing the applicator device to the digit, a power source or coupling thereto, and a tactile electrode positioned on a portion of the cartridge applicator device to contact at least a portion of the undersurface of the individual's digit; a cartridge including a first side for supporting a medicament, a second side, opposite to the first side, facing the applicator device when the cartridge is secured to the applicator device, and an active electrode accessible through the second side from the first side, wherein the active electrode is in electrical contact with said medicament and said power source when said cartridge is secured to the applicator device, such that the cartridge is positioned between the treatment site and the undersurface of the individual's digit when the undersurface of the individual's digit is in contact with the tactile electrode; whereby, upon application of the active electrode to the treatment site with a medicament interposed between said active electrode and the treatment site and completion of an electrical circuit through the active electrode, the medicament or a conductive carrier therefor, the treatment site, the individual's body, the tactile electrode and the power source, said device causes an electrical current to flow for electrokinetically driving the medicament from the cartridge into the treatment site, and a locking element carried by one of the cartridge applicator device and the second side of the cartridge and engaged with a locking surface on another one of said device and the second side of the cartridge allows for slight pivoting when engaged, said locking element is movable to release the securement between the cartridge applicator device and the cartridge enabling release of the cartridge from the device.