Patent ID: 7820106
Filing Date: 2010-10-26
Classification: B82Y,G01N

Abstract:
1. A platform for use in sample analysis, said platform having one or more sensing areas or regions, each for receiving a capture element or elements which when the platform is irradiated with coherent light can interact to provide an indication of an affinity reaction, wherein each capture element includes two or more types of capture molecule; the platform further including an optically transparent substrate having a first refractive index (n1), a thin, optically transparent layer, formed on one surface of the substrate, said layer having a second refractive index (n2) which is greater than the first refractive index (n1), said platform incorporating therein one or multiple corrugated structures comprising periodic grooves which define the one or multiple sensing regions, said grooves being configured such that coherent light incident on said platform is diffracted resulting in an abnormal high reflection of the incident light thereby generating an enhanced evanescent field at a surface of the one or multiple sensing regions; wherein the enhanced evanescent field interacts with luminescent material on or in the vicinity of the surface of the one or more of the sensing regions so as to produce a detectable luminescent signal.