Patent ID: 7728009
Filing Date: 2010-06-01
Classification: A61P,C07D

Abstract:
1. A compound of the formula: or a pharmaceutically acceptable salt thereof, wherein: R R R R wherein two of R 1 , R 2 , R 3 and R 4 are taken together to form a piperazinyl, piperidinyl, or pyrrolidinyl group; n is 1, 2 or 3; X is C═O; Y is: Each R Each R Ar is phenyl, naphthyl, biphenyl or a 5- to 13-membered heteroaryl, each of which is substituted with from 0 to 4 substituents independently chosen from: (a) hydroxy, halogen, amino, cyano, nitro, —COOH and aminocarbonyl; and (b) C R (a) hydroxy, halogen, amino, cyano, nitro, oxo, —COOH, aminosulfonyl and aminocarbonyl; and (b) C