Patent ID: 7410502
Filing Date: 2008-08-12
Classification: A61L,Y10S

Abstract:
1. A medical prosthetic device comprising a metal material having a surface, wherein the metal material is selected from the group consisting of titanium or an alloy thereof; zirconium or an alloy thereof, tantalum or an alloy thereof, hafnium or an alloy thereof, niobium or an alloy thereof and a chromium-vanadium alloy, wherein surface parts of the metal material comprises a layer of a corresponding hydroxide material selected from the group consisting of titanium hydroxide, zirconium hydroxide, tantalum hydroxide, hafnium hydroxide, niobium hydroxide, chromium hydroxide, vanadium hydroxide, and chromium-vanadium hydroxide, wherein said surface layer of hydroxide material comprises predominantly hydroxide in comparison to corresponding oxides, and wherein said hydroxide material comprises one or more biomolecule substances associated therewith, and wherein the biomolecule substance exhibits a net negative charge dissolved in a salt solution having a pH above 7.