Patent ID: 8697678
Filing Date: 2014-04-15
Classification: A61K,A61P,B82Y

Abstract:
1. An anaesthetic or sedative composition consisting of: (a) alphaxalone or a deuterated, tritiated or labelled derivative or salt thereof; (b) (7) sulfobutyl ether β-cyclodextrin (SBECD) or an alkyl ether derivative thereof; (c) an aqueous solvent suitable for injectable administration; (d) optionally alphadolone or a deuterated, tritiated or labelled derivative or salt thereof, and (e) optionally one or more additional components selected from the group consisting of a buffer, an excipient, a preservative, an anti-microbial agent, an agent that reduces toxicity and a co-polymer that improves solubility and/or stability; wherein the molar complexation ratio of alphaxalone or a deuterated, tritiated or labelled derivative or salt thereof to SBECD or an alkyl ether derivative thereof is from 1:1.6 to 1:2.5.