Patent ID: 7262186
Filing Date: 2007-08-28
Classification: A61P,C07D

Abstract:
1. A compound of Formula II: or a pharmaceutically acceptable salt or stereoisomer thereof, wherein: a is 0 or 1; b is 0 or 1; m is 0, 1, or 2; n is 0 to 2; u is 2, 3, 4 or 5; R R said alkyl, aryl, alkenyl, alkynyl, cycloalkyl, and heterocyclyl is optionally substituted with one or more substituents selected from R 5 ; or R R said alkyl, aryl, alkenyl, alkynyl, cycloalkyl, and heterocyclyl is optionally substituted with one or more substituents selected from R 5 ; or R 3 and R 3 ′ along with the nitrogen to which they are attached are combined to form ring which is a 5-12 membered nitrogen-containing heterocycle, which is optionally substituted with from one to six R 5 groups and which optionally incoporates from one to two additional heteroatoms, selected from N, O and S in the heterocycle ring; R said alkyl, aryl, alkenyl, alkynyl, cycloalkyl, and heterocyclyl is optionally substituted with one or more substituents selected from R 5 ; R said alkyl, aryl, alkenyl, alkynyl, heterocyclyl, and cycloalkyl optionally substituted with one or more substituents selected from R 6 ; R said alkyl, alkenyl, alkynyl, cycloalkyl, aryl, and heterocyclyl is optionally substituted with up to three substituents selected from R b , OH, (C 1 -C 6 )alkoxy, halogen, CO 2 H, CN, O(C═O)C 1 -C6 alkyl, oxo, and N(R b ) 2 ; R said alkyl, cycloalkyl, aryl, heterocylyl, alkenyl, and alkynyl is optionally substituted with one or more substituents selected from R 6 , or R R R