Patent ID: 6346259
Filing Date: 2002-02-12
Classification: A61K,A61Q,C07C

Abstract:
A method for preparing a betaine alkyl ester mixture, which comprises reacting a monohalogen-carboxylic acid alkyl-ester represented by the following formula (1):R1â€”Oâ€”COâ€”R2â€”Xâ€ƒâ€ƒ(1) wherein R1 is a linear or branched alkyl group or alkenyl group having 8-40 carbon atoms; R2 is a linear or branched alkylene group having 1-5 carbon atoms; and X is a halogen atom; with a tertiary amine represented by the following formula (2): wherein R3, R4 and R5 are same as or different from each other and each of them is a linear or branched alkyl group, alkenyl group or hydroxyalkyl group having 1-24 carbon atoms, using a long-chain alcohol represented by following formula (3) as a reaction solvent:Râ€”OHâ€ƒâ€ƒ(3) wherein R is a linear or branched alkyl group or alkenyl group having 8-40 carbon atoms on average; to prepare the betaine alkyl ester mixture comprising a betaine alkyl ester represented by the following formula (4): wherein R1, R2, R3, R4, R5 and X have the same meanings as defined above, and the long-chain alcohol represented by the above-mentioned formula (3).