Patent ID: 8974797
Filing Date: 2015-03-10
Classification: A61K,A61P,C07K,C12N

Abstract:
1. A recombinant virus-like particle (VLP) comprising, in operable combination: a) a Newcastle disease virus matrix (M) protein, b) a Newcastle disease virus fusion (F) protein transmembrane domain (TM) protein, c) a Newcastle Disease virus fusion (F) protein cytoplasmic domain (CT) protein, d) a type 1 protein of interest, and e) an amino acid sequence consisting of Newcastle Disease virus HR2 domain protein, wherein said transmembrane (TM) protein is flanked by said cytoplasmic domain (CT) protein and said type 1 protein of interest, and wherein said HR2 domain protein is flanked by said type 1 protein of interest and by said F protein TM.