Patent ID: 6350812
Filing Date: 2002-02-26
Classification: A61K,C08G,Y10S

Abstract:
A process for preparing a hydrogel based on triblock copolymer and on water, provided in the form of a soft hydrogel comprising an amount of water at least equal, by weight, to that of the said triblock copolymer wherein said copolymer corresponds to the formula (I):X-G-Yâ€ƒâ€ƒ(I) in which G is a non-hydroxylated hydrophilic linear polymer block comprising p repeat units, p being a number in the range of from 10 to 150, X and Y each represent a polyester block respectively comprising m and n repeat units, the ratio (m+n)/p being sufficiently high for the said copolymer to be insoluble in water and the said ratio (m+n)/p being chosen such that the addition of water to a solution of the copolymer in a water-miscible organic solvent causes the formation of a soft gel capable of retaining an amount of water at least equal to the weight of the said copolymer; said process comprising preparing a copolymer X-G-Y in a water-miscible organic solvent and contacting said copolymer and solvent with a sufficient amount of water to form a soft hydrogel.