Patent ID: 6965022
Filing Date: 2005-11-15
Classification: A61P,C12N,C12Q

Abstract:
1. A method for identifying a swine that is resistant to intestinal colonization by toxigenic E. coli that are capable of adhering to intestinal walls of swine and causing intestinal disorders in swine, said method comprising: (a) determining whether a swine has a genetic polymorphism, in both alleles wherein the polymorphism comprises a nitrogen base adenine at position 307 in the open reading frame of the alpha (1, 2) fucosyltransferase 1 gene (FUT1) (SEQ ID NO: 12), or a polymorphism in allelic association with the FUT1 polymorphism that has only adenine at position 307; and (b) inferring that the swine is resistant if the swine only has adenine at position 307 or is homozygous for a polymorphism in allelic association with FUT1 adenine in position 307.