Patent ID: 7482436
Filing Date: 2009-01-27
Classification: A61K,A61P,C07K

Abstract:
1. A gene fragment coding for a single chain Fv (hereinafter referred to as “scFv”) of a human anti-human IL-6 antibody that binds to human IL-6 with a dissociation constant (K D ) of 1.0×10 −8 M or less, said gene fragment consisting of a gene fragment coding for a VH chain of said human anti-human IL-6 antibody bound to a gene fragment coding for a VL chain of said human anti-human IL-6 antibody; wherein complementarity determining regions (CDR1 to CDR3) of said VH chain have the following amino acid sequences: and/or complementarity determining regions (CDR1 to CDR3) of said VL chain have the following amino acid sequences: