Patent ID: 6693072
Filing Date: 2004-02-17
Classification: A61K,C07K

Abstract:
A compound of the formula: or a hydrate or a pharmaceutically acceptable salt thereof,whereinP4 is Ala, bAla, Leu, Ile, Val, Nva, bVal, Nle or a bond; P3 is Ala, bAla, Leu, Ile, Val, Nva, bVal, Nle, or Lys substituted on its epsilon amino group with a morpholino-B-group; P2 is Pro(4-OBzl); R1 is a side chain of Ala, Leu, Ile, Val, Nva or bVal; X is CF2CF3 K is Z is N or CH, and B is a group of the formula: and wherein Râ€² is hydrogen or a C1-6alkyl group.