Patent ID: 6596306
Filing Date: 2003-07-22
Classification: A61K

Abstract:
A self-emulsifying drug delivery composition for use with oral administration of fat-soluble drugs, said composition consisting essentially of:a fat-soluble drug selected from the group consisting of tocotrienols, tocopherols, vitamins A, D or K, and &bgr;-carotene; an oil selected from the group consisting of palm olein and soy bean oil; and a surfactant system comprised of a first component consisting of caprylocaproyl macrogolglycerides and a second component consisting of polyoxyethylene 20 sorbitan monooleate, wherein the weight ratio of said first component to said second component is between 9/1 and 7/3 wherein said composition enhances the absorption of said fat-soluble drug and the weight ratio of the fat-soluble drug and oil to the surfactant system is about 5/1.