Patent ID: 8703987
Filing Date: 2014-04-22
Classification: A61K,C07C,C07D

Abstract:
1. A method of preparing 2-methoxyisobutylisonitrile comprising the steps of: (a) converting 2,2-dimethyloxirane to 2-methoxyisobutanol, (b) converting 2-methoxyisobutanol to 2-methoxyisobutylamine; (c) converting the 2-methoxyisobutylamine of step (b) to a compound of the formula where X is halogen, and (d) converting the compound of formula (4) to 2-methoxyisobutylisonitrile, wherein step (a) comprises adding 2,2-dimethyloxirane to a solution of acid in methanol, and step (b) comprises: