Patent ID: 6184245
Filing Date: 2001-02-06
Classification: C07D

Abstract:
A cyclic ketone compound represented by formula (I): ##STR35##where R.sup.1, R.sub.2 and R.sub.3 are independently a hydrogen atom, fluorine atom, chlorine atom, bromine atom, C.sub.1 to C.sub.10 alkyl group, C.sub.1 to C.sub.10 alkenyl group, C.sub.1 to C.sub.10 alkynyl group, C.sub.6 to C.sub.12 aryl group, C.sub.6 to C.sub.12 arylalkyl group, C.sub.6 to C.sub.12 alkylaryl group, C.sub.6 to C.sub.12 arylalkenyl group, or --(CH.sub.2).sub.p Z (where p represents an integer in the range 0 to 3, and Z represents a cyano group, carboxyl group, methylthio group, phenylthio group, trifluoromethyl group or methylthiomethyl group, with the proviso that R.sub.1, R.sub.2 and R.sub.3 are not all substituents selected from the hydrogen atom, fluorine atom, chlorine atom and bromine atom,R.sub.4 and R.sub.5 respectively independently represent a hydrogen atom, fluorine atom, chlorine atom, bromine atom, C.sub.1 to C.sub.6 alkyl group, hydroxy group, C.sub.1 to C.sub.6 alkoxy group, carboxy group or C.sub.2 to C.sub.10 alkoxycarbonyl group,R.sub.6 represents a hydrogen atom, fluorine atom, chlorine atom, bromine atom, C.sub.1 to C.sub.10 alkyl group, C.sub.6 to C.sub.12 aryl group, C.sub.6 to C.sub.12 arylalkyl group, C.sub.6 to C.sub.12 alkylaryl group, C.sub.6 to C.sub.12 arylalkenyl group, or --(CH.sub.2).sub.q G (where q represents an integer in the range 1 to 3, and G represents a hydroxyl group or C.sub.2 to C.sub.10 alkoxycarbonyl group),R.sub.7 represents a hydrogen atom, fluorine atom, chlorine atom, bromine atom, C.sub.1 to C.sub.10 alkyl group, C.sub.6 to C.sub.12 aryl group, carboxy group or C.sub.2 to C.sub.10 alkoxycarbonyl group,R.sub.8 represents a hydrogen atom or C.sub.1 to C.sub.10 alkyl group,X is O or S, andY is O or S, or pharmacologically acceptable salts thereof.