Patent ID: 7316845
Filing Date: 2008-01-08
Classification: A61K,A61L,B33Y,C08G,Y10T

Abstract:
1. A medical device or implant formed of a material with a net anionic surface, wherein the material is selected from the group consisting of metal or glass having a surface coating adsorbed thereto comprising a block copolymer in a form selected from the group consisting of brush copolymers, dendritic copolymers and linear copolymers, wherein the copolymer comprises a polycationic block comprising either a linear polycationic block or a dendritic polycationic block with a molecular weight sufficient to provide at least eight cationic charges, and at least one non-tissue binding block, wherein when the copolymer is in the form of a brush copolymer, the polycationic block is not polyethylene imine, wherein the block copolymer is applied to the surface to form a coating by ionic binding of the cationic charges to the surface, and wherein the non-tissue binding block prevents or minimizes the attachment of proteins or cells to the surface.