Patent ID: 8093418
Filing Date: 2012-01-10
Classification: B01J,C07F,C08F,Y10S

Abstract:
1. A method for the preparation of a bridged cyclopentadienyl fluorenyl metallocene structure comprising: (a) providing a 3,6-disubstituted fluorene characterized by the formula: wherein: R is a branched alkyl group having from 1 to 20 carbon atoms or a cyclic alkyl having from 5 to 20 carbon atoms; (b)reacting said 3,6-disubstituted fluorene with a brominating agent to produce a 2,7-dibromo-3,6-disubstituted fluorene characterized by the formula: (c) reacting said 2,7-dibromo-3,6-disubstituted fluorene in the presence of a palladium based catalyst with an arylboronic acid characterized by the formula: wherein: Ar is a phenyl group or a naphthyl group; to produce a 2,3,6,7-substituted fluorene characterized by the formula: or; (d) reacting said 2,7-dibromo-3,6-disubstituted fluorene with a magnesium or zinc-based Grignard reagent characterized by the formula: wherein: R′ is a C to produce a 2,7,3,6-tetrasubstituted fluorene characterized by the formula: wherein: R′ and R are as defined above; (e) reacting said 2,3,6,7-substituted fluorene with fulvene, which may be substituted or unsubstituted, to produce a bridged cyclopentadienyl fluorenyl ligand structure characterized by the formula: wherein: R″ is a C n is a number from 0-4; and R (f) reacting the bridged cyclopentadienyl flourenyl ligand structure with a transition metal/halogen compound to form the bridged cyclopentadienyl fluorenyl metallocene structure.