Patent ID: 6040290
Filing Date: 2000-03-21
Classification: A61K,C07K,G01N

Abstract:
A substantially pure protein, wherein said protein:binds to heparin-Sepharose;has an apparent molecular weight as measured by SDS PAGE under denaturing conditions of about 30 kDa;has an apparent molecular weight as measured by SDS PAGE of about 22 kDa after N-glycanase digestion;has an amino acid sequence of a peptide of approximately 22 kDa molecular weight as measured by SDS PAGE produced by in vitro translation of poly A RNA from MDA-MB-231 cells;upon hydrolysis with S. aureus V8 protease or elastase produces a peptide pattern the same as that produced by the same protease from a peptide of approximately 22 kDa molecular weight as measured by SDS PAGE produced by in vitro translation of poly A RNA from MDA-MB-231 cells.