Patent ID: 7763643
Filing Date: 2010-07-27
Classification: A61K,A61P,C07D

Abstract:
1. A method for treating acute kidney failure or chronic kidney failure, in a patient in need thereof, comprising administering to the patient a pharmaceutical composition comprising a compound of formula I or a pharmaceutically acceptable salt thereof wherein: R1 and R2 are, independently, H, F, Cl, Br, I, CN, NO R3 is hydrogen, methyl, F, Cl, Br, I, CN, S(O) R4 is hydrogen, cycloalkyl having 3, 4, 5, or 6 carbon atoms, alkenyl having 2, 3 or 4 carbon atoms, alkenylalkyl having 3 or 4 carbon atoms, ethynyl, alkylalkynyl having 3 or 4 carbon atoms, or —C R5 and R6 are hydrogen or are together a bond; and R7 and R8 are, independently, (C R7 and R8 taken together with the two carbon atoms to which R7 and R8 are attached, form a (C R7 and R8 taken together with the two carbon atoms to which R7 and R8 are attached, form a ring of the following formula