Patent ID: 6090317
Filing Date: 2000-07-18
Classification: A61K,C08G,C08L,Y10T

Abstract:
A micelle of a polyethylene oxide derivative in an aqueous solvent, said derivative being represented by the following formula (I): ##STR54## wherein A denotes a sugar residue represented by the following formula ##STR55## wherein one R denotes a covalent bond with the adjacent methylene group in formula (I); and the other R groups denote hydrogen atom, C.sub.1-5 alkyl, C.sub.1-5 alkylcarbonyl or tri-C.sub.1-5 alkylsilyl wherein the alkyl groups are the same or different or, optionally, two of said R groups in combination, while forming an acetal together with the oxygen atom to which the Rs are bound, denote C.sub.3-5 alkylidene or benzylidene whose methine may be substituted with C.sub.1-3 alkyl; a denotes an integer of 0 or 1, b denotes an integer of 2 or 3, and c denotes an integer of 0 or 1,n denotes an integer of 5-10,000,L denotes a linkage group represented by the following formula ##STR56## wherein R.sup.1 and R.sup.2 independently denote hydrogen atom, C.sub.1-6 alkyl, aryl or C.sub.1-3 alkylaryl,m denotes an integer of 2-10,000,X denotes a single bond or --CH.sub.2 CH.sub.2 --, andwhen X is a single bond, Z denotes hydrogen atom, alkali metal, acryloyl, methacryloyl, cinnamoyl, p-toluenesulfonyl, allyl, carboxymethyl, carboxyethyl, ethoxycarbonylmethyl, ethoxycarbonylethyl, 2-aminoethyl, 3-aminopropyl, 4-aminobutyl, vinylbenzyl, di-C.sub.1-5 alkyloxy-C.sub.2-3 alkyl or aldehyde-C.sub.2-3 alkyl.