Patent ID: 6013646
Filing Date: 2000-01-11
Classification: A61P,C07D

Abstract:
A composition of matter comprising: (Formula I) ##STR27## wherein Z is O or 2H, R.sub.1 is H, OH, CO.sub.2 R.sub.9, CONHR.sub.9, CH.sub.2 OR.sub.9, or CONR.sub.9 R.sub.10 ;R.sub.2 is H or OH; R.sub.3 is H or OH; R.sub.4 is H or OH;R.sub.5 is H, OH, NR.sub.9 R.sub.10, NHCOR.sub.9, OCOR.sub.9, OCR.sub.9, halide, COOR.sub.9, or CONR.sub.9 R.sub.10 ;R.sub.6 is H, OH, NR.sub.9 R.sub.10, NHCOR.sub.9, OCOR.sub.9, OCR.sub.9, halide, COOR.sub.9, or CONR.sub.9 R.sub.10 ;R.sub.7 is H, OH, O or halide;R.sub.8 is H, OH or halide; or R.sub.7 and R.sub.8 together form .dbd.O;R.sub.9 is an alkyl of 1-6 carbons, a cycloalkyl of 3-6 carbons or H;R.sub.10 is an alkyl of 1-6 carbons, a cycloalkyl of 3-6 carbons or H.