Patent ID: 7393980
Filing Date: 2008-07-01
Classification: C07B,C07C,C07D,C07F,Y02P

Abstract:
1. A process for carrying out a nucleophilic substitution on an aromatic substrate, comprising the step of: contacting said substrate of general formula (III): with a composition used as a reaction medium for reacting said substrate, said composition comprising: a) at least one ionic quatemary phosphonium compound whose cation is of general formula I′: wherein R b) a co-anion; c) a nucleophilic substituent, optionally in salt form; and d) a polar solvent, where the polar solvent is present in an amount such that the ratio by mass between the sum of the polar solvents and the sum of the phosphonium salts ([S.P.]/[P+1]), i.e. [S.P.]/(a+b), is not more than 1, and the sum of (a)+(b)+(c)+(d) represents 100% of said liquid phase; and where the molar ratio between the phosphonium compound and the substrate at the start of said reaction is at least 2/3.