Patent ID: 8357706
Filing Date: 2013-01-22
Classification: A61K,A61P,C07D

Abstract:
1. A compound having the structure of Formula I-R or I-S or a pharmaceutically acceptable salt, ester, hydrate or solvate thereof: wherein X is —NR′R″ or —OR′″; Y is —CN, —Cl, or —CF R′ is H, C R″ is H, —SO or R′ and R″ taken together with the nitrogen atom to which they are bound form a 4, 5, or 6 membered saturated heterocyclic ring containing 0 or 1 additional heteroatoms where such additional heteroatom is O or N wherein such heterocycle is optionally singly or multiply substituted with substituents independently selected from the group consisting of —OH, oxo, —NH R′″ is H, C each R each R each R each R each m is independently 0, 1, 2, or 3.