Patent ID: 7927796
Filing Date: 2011-04-19
Classification: G01N

Abstract:
1. A method of genotyping a nucleic acid sample using pairs of solid phase carriers, where members of a particular pair display a probe having a subsequence complementary to one of two different target subsequences, wherein said two different target subsequences differ from each other at one position and wherein at least some of said target subsequences, individually or together, are present in a nucleic acid sample amplified from a eukaryotic organism, and where the number of members displaying each said probe subsequence is known, comprising: reacting the nucleic acid sample with the members of the pairs of solid phase carriers such that a positive signal is generated upon reaction of a target subsequence with its complementary probe; and determining whether the target nucleic acid sample is homozygous for either of the subsequences, or is heterozygous by applying the formulas below: where =n when n when n when n