Patent ID: 6403580
Filing Date: 2002-06-11
Classification: A61K,C07D

Abstract:
A compound of the formula whereinRa denotes a benzyl or 1-phenylethyl group or a phenyl group substituted by the groups R1 and R2, wherein R1 denotes a hydrogen, fluorine, chlorine or bromine atom, a methyl, trifluoromethyl, cyano or ethynyl group and R2 denotes a hydrogen or fluorine atom, Rb denotes an â€”N(CH2CO2R3)2-group, wherein R3 denotes a hydrogen atom, a methyl or ethyl group; a R4Oâ€”COâ€”CH2â€”Nâ€”CH2â€”CH2â€”OH group optionally substituted at the methylene groups by 1 or 2 methyl or ethyl groups, wherein R4 denotes a hydrogen atom or a C1-4-alkyl group; a 2-oxo-morpholin-4-yl-group which may be substituted by 1 or 2 methyl or ethyl groups; or a N-(2-oxo-tetrahydrofuran-4-yl)-methylamino-group and n denotes an integer in the range from 2 to 4, or a tautomer or salt thereof.