Patent ID: 8071569
Filing Date: 2011-12-06
Classification: A61K,A61P,C08B

Abstract:
1. An oxidized heparin fraction having a molecular weight of from about 2,000 to about 4,000 daltons, wherein the oxidized heparin fraction is super-sulfated such that the super-sulfated oxidized heparin fraction comprises an anticoagulant reduction characteristic and an angiogenesis inhibition characteristic; wherein the super-sulfated oxidized heparin fraction has a chemical structure of a first oxidized heparin fraction after the first oxidized heparin fraction has been O-sulfated by sulfate substitution at oxygen bonds within repeating units of the first oxidized heparin fraction; and wherein the percentage of hydroxyl residues of the heparin fraction are oxidized is in a range of 25 percent to 100 percent.