Patent ID: 6380238
Filing Date: 2002-04-30
Classification: A61P,C07D

Abstract:
A compound of formula (I): wherein:R1 to R3 are independently selected from hydrogen and alkyl; R4 to R7 are independently selected from hydrogen, halogen, hydroxy, alkyl, aryl, heterocycle, alkoxy, aryloxy, alkylthio, arylthio, alkylsulfoxyl, alkylsulfonyl, arylsulfoxyl, arylsulfonyl, amino, monoalkylamino, dialkylamino, nitro, cyano, carboxaldehyde, alkylcarbonyl, arylcarbonyl, aminocarbonyl, monoalkylaminocarbonyl, dialkylaminocarbonyl, alkoxycarbonylamino, aminocarbonyloxy, monoalkylaminocarbonyloxy, dialkylaminocarbonyloxy, monoalkylaminocarbonylamino and dialkylaminocarbonylamino, wherein at least one of R4 to R7 is a substituent group other than hydrogen, and pharmaceutically acceptable salts and prodrugs thereof; and wherein R7 is selected from a group other than hydroxy and wherein the compound is other than 2,3-dihydro-1-(2-dimethylaminoethyl)-6-nitro-1H-indote or 6-amino-2,3-dihydro-1-(2-dimethylaminoethyl)1H-indote.