Patent ID: 8993609
Filing Date: 2015-03-31
Classification: A61K,A61P,C07D,C07K

Abstract:
1. A polyamide compound of the formula: or a pharmaceutically acceptable salt thereof, wherein m is 10 or 11; n is 9 or 10; Im is desamino-imidazole; each X is independently selected from 4-amino-2-carbonyl-N-methylimidazole (I), 4-amino-2-carbonyl-N-methylpyrrole (P) or β-alanine (β), subject to the proviso that the compound contains no more than two I units; γ Y is β-alanine (β) or 4-amino-2-carbonyl-N-methylpyrrole (P); and A is 3,3′-diamino-N-methyldipropylamine (Ta) or dimethylaminopropylamine (Dp), with the proviso that the polyamide compound is not ImPPPβPPβPPPγPPPβPPPβPPPβDp, ImPPPβPPβPPPγ ImPPβPIPβPPγ ImPPPPIPPPPIγPPPPPPPPPPβDp, ImPPPPPIPPPγPPPPPPPPPPβDp, or ImPPPPPPPPPPγPPPPPPPPPPPβDp.