Patent ID: 7129207
Filing Date: 2006-10-31
Classification: A61K,A61P,C07K,C12N

Abstract:
1. A method for treating a proliferative disease in a mammal, wherein the proliferative disease is characterized by cells that express a polypeptide having a function or an activity of a human K+ eag (heag) ion channel, wherein the polypeptide is encoded by a nucleic acid molecule comprising a nucleic acid sequence selected from the group consisting of: (a) a nucleic acid sequence encoding the polypeptide having the amino acid sequence SEQ ID NO: 3 (b) the nucleic acid sequence SEQ ID NO: 13; and (c) a nucleic acid sequence that hybridizes to the full-length complementary strand of the nucleic acid sequence of (a) or (b) at 4XSSC at 65° C. or at 4XSSC at 42° C. in 50% formamide, followed by washing in 0.1XSSC at 65° C. for one hour; comprising the step of introducing to the cells of the mammal in need of treatment thereof an inhibitor of said function or activity.