Patent ID: 8847175
Filing Date: 2014-09-30
Classification: A61B,G01N

Abstract:
1. A method for locating at least one optical marker in a diffusing medium, said marker having at least one optical property different from the diffusing medium, the method comprising: a) producing an optical signal by the pulsed radiation of a pulse radiation source interacting with said medium and said at least one optical marker, and performing at least one acquisition of data of said optical signal, each acquisition including a first time distribution of a component of interest in the optical signal due to said at least one marker and a second time distribution of a spurious component in the optical signal due to said medium other than said at least one marker; b) forming a multidimensional array X from said optical signal data of said at least one of said acquisitions; c) processing said array X by factorization into a product of only two non-negative multidimensional arrays A and S; and d) extracting at least one of said first time distribution and said second time distribution from said arrays A and S.