Patent ID: 7022882
Filing Date: 2006-04-04
Classification: A61K,C07B,C07C,C40B

Abstract:
1. A neuroprotectant agent selective for NMDA subtype glutamate receptors in the central nervous system, the agent comprising a compound having the formula: wherein R 1 is S-4-hydroxylbenzyl or S-2-butyl; R 2 is benzyl; R 3 is selected from the group consisting of N-methyl,N-benzylaminobutyl, S-4-hydroxybenzyl (but not when R 1 is S-4-hydroxylbenzyl), R-2-naphthylmethyl, S-isopropyl, R-isobutyl and R-2-butyl; and R 4 is selected from the group consisting of benzyl, methyl, naphthylmethyl and ethyl.