Patent ID: 8071127
Filing Date: 2011-12-06
Classification: A61K,A61P,Y02A

Abstract:
1. A method for treating a patient, comprising: aerosolizing a formulation comprising free ciprofloxacin and ciprofloxacin encapsulated in unilamellar liposomes comprised of cholesterol and hydrogenated soy phosphatidyl-choline (HSPC), wherein aerosolized particles of the formulation have a particle diameter in a range of 0.5 μm to 12 μm; and inhaling the aerosolized particles into the patient's lungs wherein the free ciprofloxacin comprises between 10% and 70% of a total of both free ciprofloxacin and encapsulated ciprofloxacin in the formulation; wherein the free and encapsulated formulations are mixed, and the mixing and aerosolizing do not degrade liposome integrity.