Patent ID: 8609716
Filing Date: 2013-12-17
Classification: A61P,C07D

Abstract:
1. A method of killing or selectively inhibiting the growth of cancer cells, of a cancer selected from the group consisting of leukemias, lymphomas, melanomas and solid tumors, in a patient in need thereof, which method comprises administering to the patient an effective amount of at least one compound of the formula: wherein: R R R wherein the R 9a substituents are the same or different and each is R 11 , C(O)R 11 , or SO 2 R 11 , wherein R 11 is H, a straight-chain or branched C 1-30 saturated alkyl, a straight-chain or branched C 2-30 unsaturated alkyl, or an aryl comprising 6-10 carbon atoms in the ring skeleton thereof, wherein R 11 is unsubstituted or substituted with one or more substituents, which are the same or different, selected from the group consisting of a halogen, an oxo, OR 11a , CO 2 R 11a and OC(O)R 11a , wherein R 11a is H, a straight-chain or branched C 1 -C 30 saturated alkyl, a straight-chain or branched C 2-30 unsaturated alkyl, or an aryl comprising 6-10 carbon atoms in the ring skeleton thereof; wherein R or a pharmaceutically acceptable salt thereof, whereupon the cancer cells are killed or their growth is selectively inhibited.