Patent ID: 6632653
Filing Date: 2003-10-14
Classification: B01L,G01N

Abstract:
An apparatus for performing a reagent protocol using polymerase chain reaction, comprising:(a) means to index patterns of reagent wells on a continuous basis through at least one step of reagent addition to said reagent wells; (b) means to index said patterns of reagent wells on a continuous basis through a plurality of individual heat transfer stations, whereby at each of said individual heat transfer stations, said patterns of reagent wells are subjected to a unique temperature change to cause one amplification step, with said plurality of individual heat transfer stations providing total amplification required for said protocol; and (c) means to seal said reagent wells following said at least one step of reagent addition to said wells, wherein said patterns of reagent wells are sealed to provide a liquid tight but peelable seal as provided by pressure sensitive adhesive or heat seal methods.