Patent ID: 8632801
Filing Date: 2014-01-21
Classification: A61K,A61M,A61P,B65B,B65D,Y02A

Abstract:
1. A method for manufacturing a transdermal delivery device, wherein said transdermal delivery device comprises a microprojection member comprising a coated array, and adhesive backing and a retainer ring; wherein the method comprises the following steps: (i) providing a microprojection member having a plurality of microprojections, an adhesive backing and a retainer ring; (ii) providing a biocompatible coating formulation comprising a biologically active agent, wherein the biologically active agent comprises hPTH or hPTH(1-34); (iii) coating the microprojection member with the biocompatible coating formulation to form said transdermal delivery device; and (iv) packaging said transdermal delivery device by heat sealing said transdermal delivery device in a foil pouch purged with nitrogen gas to form a dry inert atmosphere, wherein the step of coating further comprises depositing the biocompatible coating formulation in the range of 10 to 200 picoliters per microprojection or 0.1 to 20 nanoliters per microprojection, wherein said method further comprises pre-drying the retainer ring to effectively remove desorbed oxygen and moisture from the ring prior to pouching.