Patent ID: 7306940
Filing Date: 2007-12-11
Classification: A61N,C12M

Abstract:
1. An electroporation device comprising a signal generator comprising a pulse generator having at least two output electrodes fittable to a substrate comprising cells; said electrodes producing, in said substrate, an electric field which induces permeabilization of the membranes of said cells to facilitate introduction of substances into the cells; the device further comprising a measuring system and an electronic control unit, which constitute a regulator for controlling characteristic quantities of the signal (I 2 ) generated by the signal generator and applied to the substrate on the basis of the impedance (Z(ω)) measured in the substrate; said impedance (Z(ω)) being a function of the degree of permeabilization attained by the membranes of said cells, characterized in that said signal generator generates: a number of first pulses (I at least one second pulse ( at least one third pulse (I