Patent ID: 6203706
Filing Date: 2001-03-20
Classification: G01N,Y10S

Abstract:
Method for the detection of an analyte in a sample liquid by agglutination, comprising the steps of:contacting the sample liquid with an agglutination reagent in a reaction vessel that contains an inert matrix to form a reaction mixture,centrifuging the reaction mixture, anddetermining the reaction between the analyte and the agglutination reagent based on penetration of the agglutination reagent in the inert matrix, wherein the agglutination reagent comprises synthetic particles having an average diameter in the range of about 2-5 .mu.m and a specific density of .gtoreq.1.1, wherein the diameter and density are selected such that their sedimentation behavior towards the matrix is essentially the same as that of erythrocytes when the centrifugation is for 10 minutes at 85 g.