Patent ID: 8509879
Filing Date: 2013-08-13
Classification: A61B,G01N

Abstract:
1. A method for imaging of mean particle motion of a particle moving in a turbid medium at each point in a three dimensional wide field of view of the turbid medium using an apparatus for providing structured illumination and for providing coherent illumination comprising: imaging the particle motion in the turbid medium using the apparatus for providing structured illumination imaging using different illumination spatial frequencies of the turbid medium by the apparatus to derive static optical properties of the turbid medium; imaging the particle motion in the turbid medium using the apparatus for providing temporally coherent illumination imaging to derive dynamic motion of the particle in the turbid medium; and using a computer to generate an estimate of particle motion at each point using a correlation function model for particle motion in terms of dynamic scattering as measured by a time correlation technique including speckle contrast indicative of speckle blurring.