Patent ID: 8523878
Filing Date: 2013-09-03
Classification: A61F,A61L,C09D

Abstract:
1. A method of producing a medical instrument adapted to impart hydrophilicity and lubricity to a surface of the medical instrument by forming a coating layer on the medical instrument surface, comprising: a coating solution preparation step in which at least a water-insoluble polymer with a carboxyl group which is selected from the group consisting of hydroxypropyl methylcellulose phthalate, hydroxylpropyl methycellulose succinate acetate, cellulose phthalate acetate, and mixtures thereof, and a polyfunctional reactive compound are dissolved in an organic solvent to obtain a coating solution; an application step in which the coating solution is applied to the surface of the medical instrument to form the coating layer; a crosslinking step in which the coating layer undergoes crosslinking; and a chemical reaction step in which a chemical reaction process that is an alkali treatment is carried out to bring about hydrophilization of the crosslinked coating layer.