Patent ID: 7795228
Filing Date: 2010-09-14
Classification: A61P,C07H

Abstract:
1. A compound having the formula: wherein the bond between X and Y is a single bond or a double bond, and the bond between Y and Z is a single bond or a double bond; or optionally, Y represents a bond which is a single bond or a double bond covalently attaching X to Z; the subscript s is an integer from 0 to 1; the subscript w is an integer from 0 to 2; M is a member selected from the group consisting of oxygen; sulfur; SO; SO wherein in cycloalkyl portions of M, one or two methylene groups are optionally replaced independently of one another by NR X is selected from the (a1) and (b1): wherein in cycloalkyl groups one or two methylene groups are optionally replaced independently of one another by NR when Y is other than a single bond or a double bond, Y is selected from the group consisting of (a2), (b2), (c2) and (d2): wherein in cycloalkyl groups one or two methylene groups may be optionally replaced independently of one another by NR Z is selected from the group consisting of (a3), (b3) and (c3): wherein in cycloalkyl groups one or two methylene groups are optionally replaced independently of one another by NR Ring A is selected from the group consisting of (a4), (b4) and (c4): Q is a member selected from the group consisting of oxygen; sulfur; SO; SO wherein in cycloalkyl groups one or two methylene groups are optionally replaced independently of one another by NR R wherein alkyl, alkenyl, alkynyl, cycloalkyl and cycloalkenyl groups or portions are optionally partly or completely fluorinated or mono- or disubstituted by identical or different substituents selected from chlorine, hydroxy, C in cycloalkyl and cycloalkenyl groups one or two methylene groups are optionally replaced independently of one another by NR in N-heterocycloalkyl groups a methylene group is optionally replaced by CO or SO each R R wherein alkyl, alkenyl, alkynyl, cycloalkyl and cycloalkenyl groups or portions are optionally partly or completely fluorinated or mono- or disubstituted by identical or different substituents selected from chlorine, hydroxy, C in cycloalkyl and cycloalkenyl groups one or two methylene groups are optionally replaced independently of one another by NR in N-heterocycloalkyl groups a methylene group is optionally replaced by CO or SO R if R R R wherein alkyl, alkenyl, alkynyl, cycloalkyl and cycloalkenyl groups or portions are optionally partly or completely fluorinated or mono- or disubstituted by identical or different substituents selected from chlorine, hydroxy, C each R R R