Patent ID: 9121843
Filing Date: 2015-09-01
Classification: B82Y,C12Q,G01N,Y10T

Abstract:
1. A device comprising: a solid-state membrane, the membrane having a nanometer-scale thickness, the membrane having an aperture with at least one surface that forms a nanopore open to two opposite sides of the membrane, wherein at least a portion of an analyte is capable of passing through the nanopore, wherein an organic chemical coating comprising a self-assembled monolayer is disposed inside the walls of the nanopore, and wherein the organic chemical coating modifies at least one surface characteristic of the nanopore without specific binding between the analyte and the nanopore wherein the at least one surface characteristic of the nanopore coating includes at least one of concavity, surface charge, polarity, pH sensitivity, hydrophobicity, and functionality, to control the rate of passage of the analyte through the nanopore.