Patent ID: 6011151
Filing Date: 2000-01-04
Classification: C07D,Y02P

Abstract:
A process for preparing a .beta.-lactam halide compound represented by the formula 2A ##STR8## comprising halogenating the allenyl group of an allenyl .beta.-lactam compound of formula (1) ##STR9## with a cupric (II) halide and a metal halide to obtain the .beta.-lactam halide compound, wherein R.sup.1 is an amino or a protected amino, R.sup.2 is a hydrogen atom, R.sup.3 is a hydrogen atom or carboxylic acid protecting group, and R.sup.4 is selected from the group consisting of --CH.sub.2 OSO.sub.2 CH.sub.3 and --CH.sub.2 OSO.sub.2 CF3 wherein formula 2A has R.sup.1, R.sup.2, R.sup.3, and R.sup.4 as defined above, and X and Y are each halogen atoms.