Patent ID: 6140312
Filing Date: 2000-10-31
Classification: A61K,A61P

Abstract:
Pharmaceutical compositions from which effective non-toxic dosage amounts may be taken and applied to the skin or exposed tissue of a human, each effective dosage amount comprising pharmaceutical excipients suitable for topical application, an effective non-toxic dosage amount of a drug to treat a disease or condition of the skin or exposed tissue of a human involving a pathology, and an effective non-toxic dosage amount of a form of hyaluronic acid selected from the group consisting of hyaluronic acid and its non-toxic salts and combinations thereof sufficient to transport the drug into the epidermis or exposed tissue of the disease or condition involving a pathology to be treated wherein the dosage amount of the composition accumulates and remains in the epidermis for a prolonged period of time and which is systemic independent acting and wherein the form of hyaluronic acid present is between about 1% and about 3% by weight of the dosage amount and wherein the molecular weight of the form of hyaluronic acid is less than 750,000 daltons and greater than 150,000 daltons.