Patent ID: 8357365
Filing Date: 2013-01-22
Classification: A61K,A61Q

Abstract:
1. A method for exfoliation of the skin of an individual, the method comprising: applying to said skin a composition comprising a biologically active acylated granulysin peptide in a dose effective for topical cytolysis of keratinocytes and killing of SEQ ID NO:2 AATRVSRTGRSRWRDWSRNFMR; SEQ ID NO:3 ERVSRTGRSRWRDWSRNFMRRR; SEQ ID NO:4 RRVSRTGRSRWRDWSRNFMRRR; SEQ ID NO:5 RSRWRDVARNFMR; SEQ ID NO:6 RSRWRDVARNFMR; SEQ ID NO:7 RSRWRDWSRNFMR; SEQ ID NO:8 RSVSNAATRVSRTGRSRWRDWSRNFMR; SEQ ID NO:9 TRVARTGRSRWRDWARNFMR; SEQ ID NO:10 TRVDRTGRSRWRDWZRNFMR; SEQ ID NO:11 TRVSRTGRSRWRDVSRNFMR; SEQ ID NO:12 TRVSRTGRSRWRDWSRNFMR; SEQ ID NO:14 TRVSRTGRSRWRDWSRNFMRAA; SEQ ID NO:15 TRVSRTGRSRWRDWSRNFMRAAKKKKKKKK; SEQ ID NO:16 TRVSRTGRSRWRDWSRNFMRN; SEQ ID NO:17 TRVSRTGRSRWRDWSRNFMRNW; topical cytolysis SEQ ID NO:18 TRVSRTGRSRWRDWSRNFMRNY; SEQ ID NO:19 TRVSRTGRSRWRDWSRNFMRRR; SEQ ID NO:20 TRVSRTGRSRWRDWSRNWMRRR; SEQ ID NO:21 TRVZRTGRSRWRDWDRNFMR.