Patent ID: 6835552
Filing Date: 2004-12-28
Classification: G01N,Y10S

Abstract:
An apparatus for determining trapping of pathogens carried by a fluid by antibodies deposited in a fluidic channel, comprising:a fluidic channel having at least one pair of spaced electrodes having surfaces and with a space between said electrodes, said electrodes localized along a length of said fluidic channel, with the electrodes of said at least one pair being located on the same side of said fluidic channel, antibodies immobilized on said surfaces of said spaced electrodes and immobilized in said space between said electrodes wherein said pathogens carried by said fluid attach to said immobilized antibodies, beads coated with antibodies located in said space between said electrodes wherein said beads coated with antibodies stick to the pathogens, means for producing an electric field across said spaced electrodes, and an impedance sensor for measuring impedance between said spaced electrodes for determining trapping of said pathogens by measuring change in impedance between said pair of spaced electrodes with said beads coated with antibodies amplifying the change in impedance.