Patent ID: 8975295
Filing Date: 2015-03-10
Classification: A61K,A61L,A61P,A61Q

Abstract:
1. A method for increasing elastin content in a region of skin of a subject that is in need of increased elastin content, the method consisting essentially of applying topically a composition consisting essentially of one or more zinc-containing components in admixture with a dermatologically acceptable carrier to the region of skin of the subject, wherein the one or more zinc-containing components is selected from the group consisting of zinc acetate, zinc ascorbate, zinc aspartate, zinc butyrate, zinc caproate, zinc caprylate, zinc carbonate, zinc citraconate, zinc citramalate, zinc citrate, zinc EDTA, zinc formate, zinc fumarate, zinc gallate, zinc gluconate, zinc halides, zinc lactate, zinc malate, zinc maleate, zinc malonate, zinc metaphosphate, zinc monophosphate, zinc nitrate, zinc octoate, zinc orotate, zinc orthophosphate, zinc oxalate, zinc phosphate, zinc picolinate, zinc propionate, zinc pyrophosphate, zinc salicylate, zinc selenate, zinc succinate, zinc sulfate, zinc sulfonate, zinc tartrate, zinc tetrametaphosphate, zinc tripolyphosphate, zinc valerate, zinc amino acid complexes, zinc nucleotide complexes, and mixtures thereof, wherein zinc of the said one or more zinc-containing components is present in the composition at a concentration that increases elastin without causing epidermal sloughing and irritation due to zinc, wherein said concentration is in the range of 10 μM to 1.0 mM, and wherein the elastin content in the region of skin is increased.