Patent ID: 6824783
Filing Date: 2004-11-30
Classification: A61K,A61P,C07K,C12N,G01N,Y10S

Abstract:
A method for the inhibition of transmission of HIV-1 to a cell, comprising contacting the virus, in the presence of the cell, with an effective concentration of a peptide for an effective period of time, so that infection of the cell by the virus is inhibited, wherein the peptide has the formula:X-YTSLIHSLIEESQNQQEKNEQELLELDKWASLWNWF-Z (SEQ ID NO:1); in which:amino acid residues are presented by the single-letter code; X comprises an amino group, an acetyl group, a 9-fluorenylmethoxy-carbonyl group, a hydrophobic group, or a macromolecular carrier group; and Z comprises a carboxyl group, an amido group, a hydrophobic group, or a macromolecular carrier group.