Patent ID: 6419931
Filing Date: 2002-07-16
Classification: A61K,A61P,C07K,C12N

Abstract:
An immunogenically effective composition comprising:(i) a first peptide comprising an epitope, wherein the first peptide binds to an HLA class I molecule to form an epitope-HLA complex recognized by a human cytotoxic T cell wherein the said epitope recognized by a human cytotoxic T cell is a hepatitis B virus epitope, a hepatitis C virus epitope, a human immunodeficiency virus epitope, or a human papilloma virus epitope; (ii) a second peptide comprising an epitope, wherein the second peptide binds to an HLA class II molecule to form an epitope-HLA complex recognized by a human helper T cell; (iii) an adjuvant; and (iv) a physiologically acceptable carrier.