Patent ID: 6489359
Filing Date: 2002-12-03
Classification: C07C

Abstract:
A compound of formula I whereinZ0 denotes a group selected from the formulae â€”X1â€”(CH2)râ€”X2â€” and â€”CR4R5â€”, A1 and A2 independently of one another each denote a 1,4-phenylene- or 1,3-phenylene group, each optionally substituted by one or more halogen atoms, C1-C8-alkyl groups, C2-C8-alkenyl groups, C1-C8-haloalkyl groups or C1-C8-alkoxy groups, Z1 and Z2 independently of one another each denote a group of formula â€”X3â€”(CH2)sâ€”X4â€” or a single bond, R1 denotes hydrogen, hydroxy, â€”COOâ€”C1-C8-alkyl or â€”COOâ€”C1-C4-alkyl-phenyl, wherein said phenyl group may be substituted by C1-C4-alkyl or C1-C4-alkoxy, R2 and R3 independently of one another each denote a hydrogen or halogen atom, or a C1-C8-alkyl, C1-C8-haloalkyl, C1-C8-alkoxy, aryl, aryloxy or aralkyl group, R4 and R5 independently of one another each denote hydrogen or C1-C4-alkyl, X1 and X2 independently of one another each denote â€”Oâ€”, â€”Sâ€”, â€”NHâ€” or a single bond, X3 and X4 independently of one another each denote â€”Oâ€”, â€”Sâ€”, â€”NHâ€” or a single bond, m and n independently of one another each denote 0 or 1, and r and s independently of one another each denote an integer from 1 to 8, optionally in the form of a tautomer, racemate, enantiomer, diastereomer and mixtures thereof, or a pharmacologically acceptable salt thereof.