Patent ID: 6455689
Filing Date: 2002-09-24
Classification: A61P,C12N

Abstract:
An antisense-oligonucleotide or effective substituent-modified derivative thereof,a) wherein said antisense-oligonucleotide hybridizes with an area of a gene coding for transforming growth factor-&bgr; (TGF-&bgr;) or coding and non-coding for TGF-&bgr;b) wherein said antisense-oligonucleotide is a nucleic acid sequence selected from the group consisting of SEQ ID NOS. 10, 15-19, 24-31, 35, 39, 41, 43-45, 49, 50, 52, 72, and 137, and c) wherein said antisense-oligonucleotide has a DNA- or RNA-type structure.