Patent ID: 8597678
Filing Date: 2013-12-03
Classification: A61K,A61P,A61Q,Y10S

Abstract:
1. NLPs (Nanolipidic Particles) comprising particles formed from a hydrous monophasic precursor solution having phospholipids, water, and a non-aqueous solvent selected from the group consisting of ethanol, 1-propanol, and 2-propanol, said hydrous monophasic precursor solution having been diluted by one or more sequential dilutions of non-aqueous solvent resulting in a solvent-diluted precursor solution, and then dilution of said solvent-diluted precursor solution with an aqueous solvent to yield said NLPs sized from about 1 nm to about 20 nm, said NLPs being self-stabilizing at this size range by the retention of said aqueous solvent in said NLPs, said NLPs further retaining a concentration of said non-aqueous solvent from about 0.5% to about 14%.