Patent ID: 7026446
Filing Date: 2006-04-11
Classification: C07K

Abstract:
1. A complex formed between (i) an antibody or biologically active fragment thereof from a first species and (ii) a bifunctional molecule, the bifunctional molecule comprising a binding region of non-antibody origin which binds to the antibody of the first species and a constant region from an antibody of a second species, the constant region comprising at least one C H domain or an epitoge thereof, wherein the bifunctional molecule is bound to the constant region of the antibody of the first species, wherein the binding region comprises a protein selected from the group consisting of a mouse Fc γ receptor, histidine rich glycoprotein, Streptococcal protein G, Staphylococcal aureus protein A, Peptostreptococcus magnus protein L, and antibody-binding fragments thereof.