Patent ID: 6046214
Filing Date: 2000-04-04
Classification: C07D

Abstract:
A compound of formula I: ##STR15## wherein R is straight or branched C.sub.1-6 -alkoxy; or R is straight or branched C.sub.1-18 -alkyl, C.sub.2-18 -alkene, or C.sub.2-18 -alkyne each of which is optionally substituted with cyano, carboxylic acid, trifluoromethyl, hydroxy, perhalomethyl, halogen, C.sub.3-7 -cycloalkyl, C.sub.1-6 -alkoxy, C.sub.1-6 -alkoxycarbonyl, benzyloxycarbonyl, or --NR.sub.1 R.sub.2 wherein R.sub.1 and R.sub.2 independently are hydrogen, C.sub.1-6 -alkyl, or benzyl; or R is straight or branched C.sub.1-18 -alkyl, C.sub.2-18 -alkene, or C.sub.2-18 -alkyne each of which is optionally substituted with --SR.sub.3 wherein R.sub.3 is C.sub.1-6 -alkyl, phenyl or carbonyl(C.sub.1-6 -alkyl); or R is straight or branched C.sub.1-18 -alkyl, C.sub.2-18 -alkene, or C.sub.2-18 -alkyne each of which is optionally substituted with carbonyl(C.sub.1-6 -alkyl) or carbonylphenyl, which are optionally substituted with methoxy, nitro, halogen, or cyano; or R is straight or branched C.sub.1-18 -alkyl, C.sub.2-18 -alkene, or C.sub.2-18 -alkyne each of which is optionally substituted with phenoxy or phenyl, which are optionally substituted with trifluoromethyl, methoxy, C.sub.1-6 alkyl, carboxylic acid, nitro, cyano, halogen, phenyl, methoxycarbonyl, or methylsulfonyl; or R is straight or branched C.sub.1-18 -alkyl, C.sub.2-18 -alkene, or C.sub.2-18 -alkyne each of which is optionally substituted with --CONR.sub.4 R.sub.5, wherein R.sub.4 and R.sub.5 independently are hydrogen or C.sub.1-6 -alkyl; or R is C.sub.3-7 -cycloalkyl optionally substituted with cyano, carboxylic acid, hydroxy, oxo, perhalomethyl, halogen, phenyl, C.sub.1-6 -alkoxy, C.sub.1-6 -alkoxycarbonyl, benzyloxycarbonyl, hydroxy-C.sub.1-6 -alkyl, C.sub.1-6 -alkyl or --NR.sub.1 R.sub.2 wherein R.sub.1 and R.sub.2 independently are hydrogen, C.sub.1-6 -alkyl, or benzyl,or a pharmaceutically acceptable salt thereof.