Patent ID: 9161914
Filing Date: 2015-10-20
Classification: A61K

Abstract:
1. A method of treating a fungal infection in a patient in need thereof, comprising administering to the patient a gel composition consisting essentially of: (i) naftifine or a pharmaceutically acceptable salt thereof, present in an amount of from about 0.5 wt % to about 4 wt %; (ii) a first solvent which is a glycol solvent, present in an amount of from about 10 wt % to about 25 wt %; (iii) a second solvent which is an alkyl alcohol solvent, present in an amount of from about 10 wt % to about 25 wt %; (iv) a non-carbomer rheology modifier selected from a hydroxy cellulose, present in an amount of from about 0.75 wt % to about 2.25 wt %; (v) a polysorbate solubilizing agent present in an amount of from about 3 wt % to about 8 wt %; (vi) a pH adjuster selected from an amine base; and optionally one or more of: water, a preservative, a chelating agent, a coloring agent, and a fragrance, wherein the gel composition has a pH of about 4.5 to about 6.0.