Patent ID: 7511032
Filing Date: 2009-03-31
Classification: A61P,C07D

Abstract:
1. A compound of Formula I: wherein X is a substituent selected from the group consisting of an OH, —OR, —OSiH 3 , —OSiRR′R″, —OCOR, —OCOOR, —OCONHR, —OCSNHR, —SH, —SR, —SOR, —SOOR, —OSO 2 R, —OSO 2 H, —NHSOOR, —NH 2 , —NHCOR, —NR′COR, —NHR, —NRR′, —N 3 , —CN, halogen, —P + Ph 3 X − , —SiH 3 , —SiRR′R″, —OCSOR, —OCO(CHR) u COOR, —OCO(CHR) u SR′, —OCO(CHR) u NR′R″, —OCO(CHR) u P(═O)R′R″, —OCO(CHR) u P(═O)(OH)(R′), cysteine, glutathione, wherein each of R wherein R wherein each of R wherein the bond between the carbon to which Y is attached and the N of NR wherein each of T wherein R, R′, and R″ are independently selected from the group consisting of C wherein Y and Y′ are independently hydrogen, C 1 -C 24 alkyl, arylalkyl, C 2 -C 24 alkenyl, C 2 -C 24 alkynyl, C 1 -C 24 alkoxy, halogen, or Y and Y′ taken together form 3,4-methylenedioxy, and Y″ is hydrogen, C 1 -C 24 alkyl, C 1 -C 24 alkoxy, or halogen; naphthalenalkyl optionally substituted by methyl or halogen; phenyl(C 2 -C 24 alkenyl); wherein the phenyl is optionally substituted with methyl or halogen; cinnamyl; pyridinealkyl optionally substituted with methyl or halogen; dihydropyridinealkyl optionally substituted with C 1 -C 24 alkyl; thiophenealkyl optionally substituted with methyl or halogen; C 6 -C 14 aryl; allyl; and furanalkyl optionally substituted with methyl or halogen; wherein Z is a divalent radical of an alkane, an alkene, or an alkyne; wherein p is an integer that is greater than or equal to 2; wherein each of R wherein the bond between R wherein the bond between R or a salt thereof, wherein the compound is a solid.