Patent ID: 7262193
Filing Date: 2007-08-28
Classification: A61P,C07D

Abstract:
1. A triazaspiro[5.5]undecane derivative of the formula (I): wherein R wherein G is a bond, C1-4 alkylene, C2-4 alkenylene, or A ring is (1) C5-10 membered mono- or bi-earbocyclic ring or (2) 5-10 membered mono- or bi-cyclic hetero ring containing 1-2 nitrogen atoms and/or 1-2 oxygen atom, R6is (1) C1-4 alkyl, (2) halogen, (3) nitrile, (4) trifluoromethyl, (5) —OR (6) —SR (7) —NR (8) —COOR (9) —CONR (10) —SO (11) —NR (12) —S(O)R (13) —SO (14) —N(SO (15) C1-4 alkyl substituted by a substituent selected from (a) —OR (16) —NR wherein R R R R R R R E is a bond, —O—, —S—, —CO—, or —CHOH—, B ring is (1) C5-6 membered mono-carbocyclic ring or (2) 5-6 membered mono-cyclic hetero ring containing 1-2 nitrogen atoms and/or an oxygen atom, R n is a number from (0) or 1 to 4 and m is a number from 0 or 1 to 4, R R  wherein R R a quaternary ammonium salt thereof, an N-oxide thereof, or a non-toxic salt thereof.