Patent ID: 6830904
Filing Date: 2004-12-14
Classification: C12P

Abstract:
A method for producing D-allo-isoleucine comprising:converting (S)-2-methylbutyraldehyde to produce a hydantoin mixture containing a mixture of L-isoleucine hydantoin and D-allo-isoleucine hydantoin under conditions whereby no significant racemization of 2-methylbutyraldehyde occurs; contacting said hydantoin mixture with a D-hydantoinase to stereoselectively hydrolyze any D-allo-isoleucine hydantoin in the mixture to the corresponding N-carbamoyl-D-allo-isoleucine; and decarbamoylating the N-carbamoyl-D-allo-isoleucine to produce D-allo-isoleucine.