Patent ID: 6770300
Filing Date: 2004-08-03
Classification: A61J,A61K,B01J

Abstract:
A process for the manufacture of porous, rapidly disintegrating, active substance-containing pellets based on chitosan or a basic chitosan derivative according to a dripping method, which comprises:a) preparing an aqueous solution or dispersion, wherein chitosan or the basic chitosan derivative, one or more active substances, an acid, having a boiling point of maximally 140Â° C., and possibly further auxiliary substances are present predominantly in solution, b) dripping the aqueous solution or dispersion into a cooling liquid having a temperature of maximally âˆ’5Â° C. and is thereby solidified in the form of droplets; c) isolating the solidified droplets or pellets; and d) drying, and the acid is removed from the pellets.