Patent ID: 9211266
Filing Date: 2015-12-15
Classification: A61K,A61L,A61P,C07K

Abstract:
1. A cell construct for cell transplantation, which comprises polymer blocks of biodegradable material and cells, wherein said cells comprise two or more types of cells, said cells comprise both non-vascular cells and vascular cells, and said cells are selected from the group consisting of pluripotent cells, somatic stem cells, precursor cells, and mature cells, wherein the plural polymer blocks are arranged in spaces between the plural cells, wherein the polymer blocks each have a size from 1 μm to 700 μm, and wherein the cells are isolated cells which were grown in vitro, wherein said cell construct has a region in which the volume of the vascular cells in the central portion of the cell construct is larger than the volume of the vascular cells in the peripheral portion, wherein said central portion of the cell construct refers to a volume corresponding to a distance 80% from the center of mass in distance from the center of mass to the surface of the cell construct, and wherein said peripheral portion of the cell construct refers to a volume from the position of 80% from the center to the surface of the construct, and wherein the number of vascular cells in the central portion is 60% to 100% to the total vascular cells in the implant.