Patent ID: 6534513
Filing Date: 2003-03-18
Classification: C07C,C07D

Abstract:
A compound of formula (1): whereinAr1 is an aromatic or heteroaromatic group; R1, R2, R3, R4 and R5 which may be the same or different is each an atom or group â€”L2(Alk3)tL3(R7)u in which L2 and L3 which may be the same or different is each a covalent bond or a linker atom or group, t is zero or the integer 1, u is an integer 1, 2 or 3, Alk3 is an aliphatic or heteroaliphatic chain and R7 is a hydrogen or halogen atom or a group selected from alkyl, â€”OR8 (where R8 is a hydrogen atom or an optionally substituted alkyl group), â€”SR8, â€”NR8R9 (where R9 is as just defined for R8 and may be the same or different), â€”NO2, â€”CN, â€”CO2R8, â€”SO3H, â€”S(O)R8, â€”SO2R8, â€”OCO2R8, â€”CONR8R9, â€”OCONR8R9, â€”CSNR8R9, â€”COR8, â€”OCOR8, â€”N(R8)COR9, â€”N(R8)CSR9, â€”SO2N(R8)(R9), â€”N(R8)SO2R9, â€”N(R8)CON(R9)(R10), (where R10 is a hydrogen atom or an optionally substituted alkyl group) â€”N(R8)CSN(R9)(R10) or â€”N(R8)SO2N(R9)(R10); Alk1 is an optionally substituted aliphatic or heteroaliphatic chain; L1 is a covalent bond or a linker atom or group; Alk2 is a straight or branched alkylene chain; m is zero or an integer 1; R6 is a hydrogen atom or a methyl group; r is zero or the integer 1; R is a carboxylic acid (â€”CO2H) or a carboxylic acid ester or amide; Ra is a hydrogen atom or a methyl group; A is an optionally substituted aliphatic, heteroaliphatic, cycloaliphatic, polycycloaliphatic, heterocycloaliphatic, polyheterocycloaliphatic, aromatic or heteroaromatic group; and the salts solvates, hydrates and N-oxides thereof.