Patent ID: 7166469
Filing Date: 2007-01-23
Classification: G01N,Y10S,Y10T

Abstract:
1. A method for obtaining an indication of the coronary artery disease state of an individual, the method comprising: (a) obtaining a sample from the individual; and (b) making a comparison of a level of a marker in the sample with the level of the same marker in a control, the marker being one of the following: (i) a first marker comprising an atherogenic protein comprising oxidized low density lipoprotein (OxLDL), (ii) a second marker comprising an atherogenic protein comprising malondialdehyde-modified low density lipoprotein (MDA-modified LDL), and (iii) a third marker for acute myocardial infarction, such a comparison being made for the second marker and such a comparison being made for at least one of the first marker and the third marker; wherein results obtained from step (b) provide the following indications if such a comparison is made for each of the three markers:  or provide the following indications if such a comparison is made for each of the first and second markers:  or provide the following indications if such a comparison is made for each of the second and third markers:  wherein “+” indicates that an assay for the marker of the comparison in question indicates that the level of the marker in the sample from the individual is higher compared to the level of the same marker in the control and “−” indicates that the assay for the marker of the comparison in question indicates that the level of the marker in the sample from the individual is not higher compared to the level of the same marker in the control, the control providing results based on those of a normal population.