Patent ID: 8759316
Filing Date: 2014-06-24
Classification: A61K

Abstract:
1. A method of transitioning a patient in need thereof from administration of cangrelor during percutaneous coronary intervention (PCI) to administration of cangrelor in preparation for surgery, the method comprising: (1) administering a PCI dosing regimen, wherein the PCI dosing regimen comprises (i) administering intravenously a 30 μg/kg bolus of cangrelor before the start of PCI; and (ii) administering intravenously a continuous infusion of cangrelor at an infusion rate of 4 μg/kg/min after administration of the bolus; (2) discontinuing the administration of the PCI dosing regimen; and (3) administering a bridge dosing regimen, wherein the bridge dosing regimen comprises administering intravenously a continuous infusion of cangrelor at an infusion rate of 0.75 μg/kg/min.