Patent ID: 8524753
Filing Date: 2013-09-03
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A method for improving the pharmacokinetics of a drug which is metabolized by cytochrome P450 monooxygenase comprising co-administering to a human in need of such treatment a combination of a therapeutically effective amount of said drug or a pharmaceutically acceptable salt thereof, and an amount of a compound or combination of compounds of formula I or a pharmaceutically acceptable salt, prodrug, salt of a prodrug, or combination thereof effective to inhibit cytochrome P450 monooxygenase, wherein the compound of formula I corresponds to the following structure: R R R R m is 0-3; n is 0-3; A A X L is p is 1-5; R R R R q is 0-3; X A R R R wherein any one of the