Patent ID: 6828312
Filing Date: 2004-12-07
Classification: A61K,A61P,C07F

Abstract:
A method for treating a mammal suffering from a blood coagulation disorder, comprising administering to the mammal a therapeutically effective amount of a compound of the following Formula I:Arâ€”(CXY)mâ€”(Het)0 or 1â€”(CXâ€²Yâ€²)nâ€”C(Z)pâ€”(PO3)3-pâ€ƒâ€ƒI wherein Ar is optionally substituted carbocyclic aryl or optionally substituted heteroaryl; Het is optionally substituted N, O, S, S(O) or S(O2); each X, each Y, each Xâ€², each Yâ€² and each Z are each independently hydrogen; halogen; hydroxyl; sulfhydryl; amino; optionally substituted alkyl; optionally substituted alkenyl; optionally substituted alkynyl; optionally substituted alkoxy; optionally substituted alkylthio; optionally substituted alkylsulfinyl; optionally substituted alkylsulfonyl; or alkylamino; m and n each is independently an integer of from 0 to 4; p is 1 or 2; and pharmaceutically acceptable salts thereof.