Patent ID: 7638535
Filing Date: 2009-12-29
Classification: A61P,C07D

Abstract:
1. A compound of formula (I) a stereochemically isomeric form thereof, an N-oxide form thereof, or a pharmaceutically acceptable acid or base addition salt thereof, wherein —R wherein in said bivalent radicals optionally one or two hydrogen atoms on the same or a different carbon atom may be replaced by C 1-6 alkyl or hydroxy, R R R L is hydrogen, or L is a radical of formula  wherein each Alk is C R R X is O, S, SO R Y is a direct bond; Z is a direct bond or O; R aryl represents unsubstituted phenyl or phenyl substituted with 1, 2 or 3 substituents each independently selected from halo, hydroxy, C Het is tetrahydrofuranyl; tetrahydrofuranyl substituted with C