Patent ID: 8389707
Filing Date: 2013-03-05
Classification: A61K,B01J,C07H

Abstract:
1. An oligonucleotide structure, comprising a first strand of nucleic acid and a second strand of nucleic acid, the first and second strands being hybridized to each other in a duplex section, and at least two hydrophobic anchoring moieties capable of being attached to a lipid membrane, wherein a terminal end of the first strand is not part of the duplex section and is free from a hydrophobic moiety, wherein the hydrophobic anchoring moieties are covalently attached to adjacent terminal ends of the first and second strands, respectively, and wherein the oligonucleotide structure is immobilized to a surface by binding to a surface-immobilized linker or by binding to a lipid membrane-attached linker.