Patent ID: 8131337
Filing Date: 2012-03-06
Classification: A61B

Abstract:
1. A method for monitoring early treatment response of a cancer treatment in a patient comprising localizing a cancerous tissue in the patient, obtaining a Nuclear Magnetic Resonance (NMR) spectrum of the localized cancerous tissue, subjecting the patient to the cancer treatment, obtaining an NMR spectrum of the same tissue after subjecting the patient to the cancer treatment, wherein the NMR spectra are obtained by interrogating one or more nuclei selected from the group consisting of 31 P, 1 H, and 13 C, and measuring from the NMR spectra the amount of Choline naturally present or formed in the endomembranes of the cancerous tissue before and after the cancer treatment, wherein said Choline is a metabolite of phospholipid metabolism occurring in the body of the cancer patient, wherein said cancer treatment comprises administration of cytotoxic therapy, whereby a decrease in the amount of Choline after treatment is indicative of a positive response.