Patent ID: 6197993
Filing Date: 2001-03-06
Classification: C07C,C07D

Abstract:
A naphthyloxyacetic acid derivative of the general formula (I) ##STR336##wherein A is(i) hydrogen;(ii) -(C1-4 alkylene)-OH; or(iii) -(C1-4 alkylene)-CN;E is (i) single bond or(ii) C1-6 alkylene;G is --S--, --SO-- or --SO.sub.2 --,L is (i) C1-6 alkylene,(ii) --(CH.sub.2).sub.m --CH.dbd.CH--(CH.sub.2).sub.n -- in which m is 0 or an integer of 1-3, n is 0 or an integer of 1-3 or(iii) --(CH.sub.2).sub.x --CH(OH)--(CH.sub.2).sub.y -- in which x is an integer of 1-3, y is 0 or an integer of 1-3; ##STR337##in which each phenyl group is optionally substituted by 1-3 of C1-4 alkyl, C1-4 alkoxy, halogen, nitro or trifluoromethyl; in the formula ##STR338## ##STR339##is single bond or double bond; with the proviso that,(1) when G is --SO-- or --SO.sub.2 --, M is neither ##STR340##in which each phenyl group is optionally substituted by 1-3 of C1-4 alkyl, C1-4 alkoxy, halogen, nitro or trifluoromethyl,(2) when m in L is 0, G is --SO-- or --SO.sub.2 --,(3) when n in L is 0, M is ##STR341##in which each phenyl group is optionally substituted by 1-3 of C1-4 alkyl, C1-4 alkoxy, halogen, nitro or trifluoromethyl,(4) when y in L is 0, M is ##STR342##in which each phenyl group may be substituted by 1-3 of C1-4 alkyl, C 1-4 alkoxy, halogen, nitro or trifluoromethyl, and(5) when A is hydrogen, L is --(CH.sub.2).sub.m --CH.dbd.CH--CH.sub.2).sub.n -- in which m is 0 or an integer of 1-3 and n is 0 or an integer of 1-3 or --(CH.sub.2).sub.x -CH(OH)--(CH.sub.2).sub.y -- in which x is an integer of 1-3 and y 0 or an integer of 1-3 or non-toxic salt thereof, non-toxic acid addition salt thereof or their hydrate.