Patent ID: 6537566
Filing Date: 2003-03-25
Classification: A61K,Y10S,Y10T

Abstract:
A non-systemic, non-invasive or minirally invasive method of treating uterine fibroids by inhibiting the growth of uterine fibroid cells comprising the steps of:providing a dose of a composition, the composition including a fibroid cell growth inhibitor agent, the agent being a substrate or an analogue or derivative of a substrate that is normally present and physiologically well tolerated in humans and selected from the group consisting of: a tocopherol, a tocopherol derivative, a tocopherol analogue, a protein kinase C inhibitor, and a mitogen activated protein kinase inhibitor; transporting the agent non-systemically into a milieu of the uterine fibroid cells to be inhibited; and exposing the uterine fibroid cells in the milieu to the agent to inhibit the growth of the uterine fibroid cells by increasing a background concentration of the agent in the milieu to a level sufficient to inhibit growth of the uterine fibroid cells.