Patent ID: 6815458
Filing Date: 2004-11-09
Classification: A61K,A61P,C07D

Abstract:
A compound of formula (I) wherein Z is in which R is a hydrogen, a cyclic or straight-chained or branched acyclic organyl group, a lower hydroxyalkyl group, a lower aminoalkyl group, or an aralkyl or heteroaralkyl up; n is 1; X1 is methylene, vinylene, or an NH or N(lower alkyl) group; and X2 is methylene, or, when X1 is methylene or vinylene, X2 is methylene or a bond; or when X1 is methylene, X2 is O, S, NH, or N(lower alkyl) or a bond; Y1 is methylene and Y2 is methylene, vinylene, ethylene, propylene, or bond; or Y1 is a bond and Y2 is vinylene; or Y1 is ethylene and Y2 is O, S, NH, or N(lower alkyl); Ar1 and Ar2 independently are unsubstituted or substituted aryl or heteroaryl groups, provided that Ar1 and Ar2 are not simultaneously unsubstituted phenyl; and W is oxygen; or a pharmaceutically acceptable salt or prodrug thereof.