Patent ID: 7834138
Filing Date: 2010-11-16
Classification: A61K,A61P,C08G,Y10S

Abstract:
1. A composition comprising (i) a pharmaceutical carrier and (ii) a conjugate of a water soluble polymer and a pharmacologically active agent, wherein the pharmacologically active agent is covalently attached to the water soluble polymer via a functional group Y, and wherein the water soluble polymer comprises: (a) a first water soluble polymer segment which is at least 4 and at most about 2000 monomeric units in length (POLY (b) a second water soluble segment which is 1 to about 120 monomeric units in length (POLY wherein the molecular weight of POLY (c) a linkage X, which covalently attaches POLY wherein X is an amide, a carbamate, an ester, a urea, an amine, a thioether, or a disulfide linkage; one or more optional spacer groups linking X to POLY (d) said functional group, Y, attached to POLY wherein each of POLY