Patent ID: 6252077
Filing Date: 2001-06-26
Classification: C07D

Abstract:
A compound of the formula: ##STR38##or the pharmaceutically acceptable salts thereof wherein:R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.7, R.sub.8 and R.sub.9 are the same or different and represent hydrogen, halogen, hydroxy, lower alkyl, or lower alkoxy;X represents carbon or nitrogen provided thatwhere X is carbon, R.sub.6 represents hydrogen, halogen, hydroxy, lower alkyl having 1-6 carbon atoms, or lower alkoxy; andwhere X is nitrogen, R.sub.6 represents an electron pair;Y represents carbon or nitrogen provided thatwhere Y is carbon, R.sub.10 represents hydrogen, halogen, hydroxy, lower alkyl, or lower alkoxy; andwhere Y is nitrogen, R.sub.10 represents an electron pair;Z represents carbon or nitrogen provided thatwhere Z is carbon, R.sub.11 represents hydrogen, halogen, hydroxy, lower alkyl, or lower alkoxy, or phenyl optionally substituted with one or two groups selected from hydrogen, halogen, hydroxy, lower alkyl, or lower alkoxy; andWhen Z is nitrogen, R.sub.11 represents an electron pair;R.sub.5 is hydrogen or lower alkyl;m is an integer of from 2-5;n is 0, or an integer of from 1-4;R.sub.12 and R.sub.13 independently represent lower alkyl;R.sub.7 and R.sub.8 together may represent a benzo ring optionally substituted with up to four substitutents selected from hydrogen, halogen, hydroxy, lower alkyl, or lower alkoxy; andR.sub.14, R.sub.15, R.sub.16 and R.sub.17 are the same or different and represent hydrogen or lower alkyl.