Patent ID: 8431738
Filing Date: 2013-04-30
Classification: A61P,C07B,C07F

Abstract:
1. A method for producing an optically active BSH amino acid, comprising the step of reacting an optically active α-amino acid derivative having a halogen in a side chain with a cyanoethyl BSH compound represented by the formula: wherein said amino acid derivative is represented by the structural formula: a coupling manner of an amino group or carboxyl group to α carbon is optical isomers sterically in D-form or L-form, while X represents one halogen atom selected from the group consisting of a chlorine atom, a bromine atom, an iodine atom, and a fluorine atom, A represent a linear alkylene, a branched alkylene or a substituted alkylene, n represents an integer of from 1 to 10, and R represents a linear alkylene, branched alkylene, or substituted alkylene having 1 to 6 carbon atom.