Patent ID: 8506928
Filing Date: 2013-08-13
Classification: A61K

Abstract:
1. A composition for delivering a compound to a cell, comprising: at least one peptide comprising a free C-terminus and a linked N-terminus and a plurality of amino acid residues, said peptide comprising a C-terminal arginine residue positioned at said free C-terminus of said peptide, wherein said peptide targets said composition to said cell; a particle for carrying said compound, wherein said particle comprises at least one lipid molecule and a brush layer comprising 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (‘DSPE-PEG2000); and a linking molecule, wherein said linking molecule links said at least one peptide at said linked N-terminus to said particle.