Patent ID: 8855772
Filing Date: 2014-10-07
Classification: A61N

Abstract:
1. A system, comprising: an external patient management (EPM) system configured to receive information about a chemical characteristic indicative of a physiological state of a subject, the EPM system including a memory and a control, the controller configured to provide trend information derived from the chemical characteristic received over time using the memory and to calculate a neural stimulation energy using the trend information, wherein the chemical characteristic includes at least one of matrix metalloproteinase, tissue inhibitor of metalloproteinases, brain natriaretic peptide, atrial natriaretic peptide, C-reactive protein, vascular adhesion protein, semicarbazide-sensitive amine oxidase, protein kinase B, AKT, phospholamban, phosphorylated phospholamban, catecholamine, norephinepherine, cytokine, tumor necrosis factor-alpha, fas ligand, interleukin, neurotransmitter, acetylcholine, serotonin, or neuropeptide-Y.