Patent ID: 6210449
Filing Date: 2001-04-03
Classification: C07D,C09B,C11D,D06L,D06M,D06P,D21H,Y10S

Abstract:
A compound having the formula: ##STR22##in which X is or NH; M is hydrogen, an alkali metal atom, ammonium or a cation formed from an amine; each R.sub.1, independently, is a non-aromatic aminoacid residue from which a hydrogen atom on the amino group has been removed; n is 1 or 2; and each R.sub.2, independently, is hydrogen, C.sub.1 -C.sub.3 alkyl, halogen, cyano, COOR in which R is hydrogen or C.sub.1 -C.sub.3 alkyl, CONH--R in which R has its previous significance, SO.sub.2 NH--R in which R has its previous significance, NH--COR in which R has its previous significance, SO.sub.3 M in which M has its previous significance or, when n is 1, R.sub.2 can also be CO--R.sub.3 in which R.sub.3 is C.sub.1 -C.sub.3 alkyl or phenyl; provided that those compounds are excluded in whicha) X is NH, n is 1 and R.sub.2 is SO.sub.3 M in which M has its previous significance; orb) X is NH, n is 2 and one R.sub.2 is SO.sub.3 M in which M has its previous significance, and the other R.sub.2 is hydrogen, methyl or halogen; orc) X is NH, n is 1, R.sub.1 is glycine and R.sub.2 is H or CO.sub.2 H; or X is NH, n is 2, each R.sub.2 is SO.sub.3 M in which M has its previous significance and the SO.sub.3 M groups are in 2,5-positions in the phenyl ring and R.sub.1 is D,L-alanine, L-valine, L-leucine, L-isoleucine, L-threonine, L-aspartic acid, L-glutamic acid, L-phenylalanine, L-proline, D,L-methionine or glycine.