Patent ID: 8379197
Filing Date: 2013-02-19
Classification: G01J,G01N,G02B

Abstract:
1. A method comprising: selecting a pre-determined vector space that mathematically describes a first plurality of reference spectral data sets for normal cells and a second plurality of reference spectral data sets for cells having undergone a biochemical change; irradiating a sample containing at least one cell to thereby generate photons selected from the group consisting of: photons emitted from the sample, photons absorbed by the sample, photons reflected from the sample, photons scattered by the sample, and combinations thereof; collecting said photons to thereby generate a target spectral data set; transforming the target spectral data set into said pre-determined vector space; analyzing a distribution of transformed data in the pre-determined vector space; and based on said analysis, classifying at least one cell as a normal cell or a cell having undergone a biochemical change.