Patent ID: 6582716
Filing Date: 2003-06-24
Classification: A61K

Abstract:
A method for treating wounds, promoting healing and avoiding amputations in diabetic and non-diabetic patients by improving the dietary fuel capabilities and correct an overutilization of free fatty acids thereby enhancing available energy in tissue surrounding an affected area comprising the steps of:a) determining a steady baseline respiratory quotient of a patient and obtaining a subsequent respiratory quotient every 30 minutes, the steady baseline respiratory quotient being two identical consecutive respiratory quotients less than 0.90 measured five minutes apart, b) having the patient consume a liquid or food containing 60 to 100 grams of glucose, c) administering a pulse of insulin through an intravenous site at a six minute interval of time until the subsequent respiratory quotient shows an improvement over the steady baseline respiratory quotient, the pulse of insulin being 20 to 35 milliunits of insulin per kilogram of body weight for a non-diabetic and a Type I diabetic, the pulse of insulin being 70-200 milliunits of insulin per kilogram of body weight for a Type II diabetic, the improvement over the steady baseline respiratory quotient being a respiratory quotient of 0.90 or greater, the subsequent respiratory quotient improvement over the steady baseline respiratory quotient being a measurement of increased glucose oxidation by tissue surrounding the affected area; d) allowing the patient to rest one hour, and e) repeating the steps a-d at least three times.