Patent ID: 6533912
Filing Date: 2003-03-18
Classification: B01J,C40B,G01N

Abstract:
A method of analysis of molecules in a capillary dimension channel(s) filled with a separation media, the method using electrophoretic separation to separate small compounds, the method comprising:a) injecting a sample into a injection end of said capillary dimension channel, said sample including at least one small molecule and at least one quality metric standard compound; b) introducing an electric field through the capillary dimension channel for a selected period of time, whereby said electric field causes compounds in said sample to migrate away from said injection end; c) repeating steps a and b at least one time; and d) detecting at a detection location said at least one small molecule and at least one quality metric standard compound; wherein said detection location is separated from said injection end by a length of the capillary dimension channel; wherein said selected period of time is sufficient to allow the compounds in each sample to be detectably separated at the detection location; wherein every sample injected into the capillary dimension channel is continuously detected.