Patent ID: 6991807
Filing Date: 2006-01-31
Classification: A61K,A61P

Abstract:
1. A once-a-day antibiotic product comprising: first, second, and third dosage forms, wherein each of said dosage forms includes at least one antibiotic and a pharmaceutically acceptable carrier; one of said dosage forms includes at least a first antibiotic and another of said dosage forms includes at least a second antibiotic that is different from the first antibiotic; wherein said first and second antibiotics are each selected from the group consisting of protein synthesis inhibiting antibiotics and non-protein synthesis inhibiting antibiotics; and wherein when said first antibiotic is a protein synthesis inhibiting antibiotic said second antibiotic is a non-protein synthesis inhibiting antibiotic; and wherein when said first antibiotic is a non-protein synthesis inhibiting antibiotic said second antibiotic is a protein synthesis inhibiting antibiotic; said first dosage form is selected from the group consisting of immediate release dosage forms and delayed release dosage forms; said second and third dosage forms are delayed release dosage forms; each of said first, second, and third dosage forms initiates release of antibiotic at different times and Cmax in serum of the total antibiotic released from said antibiotic product is achieved in less than about 12 hours from administration when said first dosage form is an immediate release dosage form, or Cmax in serum of the total antibiotic released from said antibiotic product is achieved in less than about 12 hours after initial release of antibiotic when said first dosage form is a delayed release dosage form; and said once-a-day antibiotic product contains the total dosage of said first and second antibiotics for a twenty-four hour period.