Patent ID: 6399783
Filing Date: 2002-06-04
Classification: C07C,C07D

Abstract:
A method for preparing a compound having the structure VII: wherein,R15 and R16 are, independently, hydrogen, Si(R21)3 or C(O)R22, wherein each R21 is, independently, branched or straight chain C1-C12 alkyl; and R22 is substituted or unsubstituted aryl, aralkyl or from C1-C12 branched or straight chain alkyl; R17 is substituted or unsubstituted aryl, aralkyl, or from C1-C12 branched or straight chain alkyl; R18 is branched or straight chain C1-C12 alkyl; unsubstituted or substituted aryl; aralkyl; Si(R28)3 or C(O)R29, wherein, each R28 is, independently, branched or straight chain C1-C12 alkyl; or aralkyl; R29 is substituted or unsubstituted aryl, aralkyl or from C1-C12 branched or straight chain alkyl; R19 and R20 are, independently, branched or straight chain C1-C12 alkyl, aryl, aralkyl, or C(O)OR30; R30 is branched or straight chain C1-C12 alkyl; and V and W are, independently, sulfur, oxygen, or NR43, wherein R43 is hydrogen; branched or straight chain C1-C12 alkyl; or aralkyl, comprising,(a) admixing (i) a compound having the structure X wherein R18-R20 are as above, (ii) a Lewis acid; and (iii) a base, to produce a first intermediate; (b) reacting the first intermediate of step (a) with a compound having the structure XI: wherein R15 and R17 are as above, to produce a second intermediate; and (c) admixing the second intermediate of step (b) with a proton source.