Patent ID: 6812332
Filing Date: 2004-11-02
Classification: C07H

Abstract:
A method of detecting the presence of a sialidase in a sample comprising contacting a chromogenic sialidase substrate compound comprising the formula of General Structure I or a composition comprising a chromogenic sialidase substrate of General Structure I and detecting a visible color change that indicates the presence of a sialidase, wherein the chromogenic sialidase substrate compound comprises: wherein R1, R2, R4, or R5 are substituents selected from the group consisting of H, R6, Cl, Br, I, F, and NO2, provided that at least two of said substituents are substituted with H;R3 is CH&boxH;CHNO2, R6 is H, CH(CH3)2, (CH2)mCH3 and m is an integer from 0 to 3; or salts of said chromogenic sialidase substrate compounds.