Patent ID: 7989532
Filing Date: 2011-08-02
Classification: A61L,C07K

Abstract:
1. An RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid)/β-tricalcium phosphate composite material, comprising a two-phase mixture of β-tricalcium phosphate particles and RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid), the RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) consisting of the following molecular structure: the number average molecular weight of RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) is 30,000-300,000; the mole content of L-lysine in RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) is 0.1%-5%; β-tricalcium phosphate particles are uniformly dispersed in the RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) matrix, and the mass ratio of β-tricalcium phosphate particles and RGD polypeptide grafted poly (glycolic acid-L-lysine-L-lactic acid) is between 1:10 and 1:100.