Patent ID: 6291529
Filing Date: 2001-09-18
Classification: C07C,Y10S

Abstract:
A therapeutic method for treating glaucoma, said method comprising administering to a hypertensive patient a therapeutically-effective amount of a compound of Formula I: ##STR16##wherein each of R.sup.1 and R.sup.11 is a group independently selected from hydrido, alkyl, alkylaminoalkyl and phenyl; wherein p is a number selected from zero through five, inclusive; wherein r is a number selected from zero, one and two; wherein R.sup.2 is selected from hydrido and alkyl; wherein R.sup.3 is a group selected from hydrido, cycloalkylalkyl, aralkyl and haloaralkyl; wherein each of R.sup.4 and R.sup.6 is a group independently selected from hydrido and methyl; wherein R.sup.5 is selected from ##STR17##wherein V is selected from hydrido, alkyl, cycloalkyl, aryl and aralkyl; wherein each of R.sup.9 and R.sup.10 is a group independently selected from hydrido, alkyl, alkenyl, alkynyl, cycloalkyl and aryl; wherein m is a number selected from zero through three; wherein n is a number selected from zero through three; wherein R.sup.7 is a group selected from alkyl, cycloalkylalkyl and aralkyl; wherein R.sup.8 is a group selected from hydrido, alkyl, hydroxyalkyl, cycloalkyl, cycloalkylalkyl, alkenyl and haloalkenyl; wherein each of R.sup.12 and R.sup.13 is a group independently selected from hydrido, alkyl, cycloalkyl, cycloalkylalkyl, alkylacyl, aryl, aralkyl, haloaryl and haloaralkyl; and wherein any one of said R.sup.1 through R.sup.13 groups having a substitutable position may be substituted with one or more groups selected from alkyl, hydroxy hydroxyalkyl, halo, alkoxy, alkoxyalkyl and alkenyl; or a pharmaceutically-acceptable salt thereof.