Patent ID: 9067944
Filing Date: 2015-06-30
Classification: A61P,C07C,C07D

Abstract:
1. A process for the preparation of a compound of formula (A), or a salt thereof: wherein: R V and W are independently chosen from the group consisting of: H, F, Cl, I, Br, CN, C X and Y are independently selected halo's; and R the process comprising the steps of: (a) reacting a compound of the formula (X): with a glycine derivative of the formula (XI) in the presence of a suitable base and a suitable solvent to form an imine compound of the formula (XII) (b) reducing the imine compound of formula (XII) with a suitable reducing agent to form the compound of formula A; and (c) optionally isolating the compound of formula A in the form of an acid addition salt by reacting the compound of formula A with an suitable acid.