Patent ID: 9134326
Filing Date: 2015-09-15
Classification: A61P,G01N

Abstract:
1. A method of diagnosing or prognosing liver fibrosis in a subject comprising: detecting at least two, at least 3, at least 4, or at least 10 liver fibrosis-related molecules listed in any of Tables 1, 2, 3, 5, 6 and 12 and any of SEQ ID NOS: 1-5544 in a sample obtained from the subject; comparing expression of the at least two liver fibrosis-related molecules to controls representing expression of the at least two liver fibrosis-related molecules expected in a subject who does not have liver fibrosis; and diagnosing or prognosing liver fibrosis in the subject when differential expression of the at least two liver fibrosis-related molecules between the sample and the control is detected, wherein differential expression comprises an increase or decrease of at least 10% relative to the controls.