Patent ID: 6203808
Filing Date: 2001-03-20
Classification: A61K,A61Q,C07C,C07F,Y10S

Abstract:
An aqueous dispersion of lipid spherules comprising organized molecular layers enclosing an encapsulated aqueous phase, said layers comprising at least one compound of formula (I) in combination with at least one lipid compound, said at least one lipid compound differing from said at least one compound of formula (I), said compound of formula (I) having the following structure:R.sup.1 --CH(OH)--CH(CH.sub.2 OH)--NH--CO--NR.sup.2 R.sup.3 (I)in which:R.sup.1 is chosen from saturated and unsaturated, linear and branched, C.sub.9 to C.sub.23 alkyl radicals which may be optionally hydroxylated,R.sup.2 is chosen from hydrogen and saturated and unsaturated, linear and branched, C.sub.1 to C.sub.8 alkyl radicals, andR.sup.3 is chosen from saturated and unsaturated, linear and branched, C.sub.1 to C.sub.32 alkyl radicals which may be optionally substituted with at least one hydroxyl radical, wherein said at least one hydroxyl radical can be substituted by a radical chosen from saturated and unsaturated, linear and branched, C.sub.1 to C.sub.24 acyl radicals; R.sup.3 can optionally be interrupted by 1 to 7 heteroatoms.