Patent ID: 6984495
Filing Date: 2006-01-10
Classification: A61K,C07K

Abstract:
1. An isolated polypeptide having at least one biological activity of Hairless wherein, said activity is selected from the group consisting of transcriptional activity and the ability to bind thyroid hormone receptor, wherein said polypeptide is encoded by a polynucleotide containing at least one human nucleotide sequence of at least 250 contiguous nucleotides of SEQ ID NO:1 selected from the group consisting of: (a) a nucleotide sequence which hybridizes to SEQ ID NO:1 under stringent hybridization conditions at 65° C. in a buffer of 500 mM NaHPO (b) a nucleotide sequence which has greater than 98% identity to SEQ ID NO:1, and, (c) a nucleotide sequence encoding at least 75 contiguous amino acids of SEQ ID NO:2.