Patent ID: 9127324
Filing Date: 2015-09-08
Classification: C12N,C12P,C12Y

Abstract:
1. An isolated Mycobacterium smegmatis -derived O-phosphoserine sulfhydrylase (OPSS) mutant, having O-phosphoserine sulfhydrylase activity and the same amino acid sequence as that of SEQ ID NO: 1 except for deletion of the last three to seven C-terminal amino acids of SEQ ID NO: 1, and (i) substitution of the proline residue (Pro) at position 77 of SEQ ID NO: 1 with a serine residue (Ser), or (ii) substitution of the threonine residue (Thr) at position 131, the lysine residue (Lys) at position 137, and the threonine residue at position 238 of SEQ ID NO: 1 with an alanine residue (Ala), an asparagine residue (Asp), and a serine residue (Ser), respectively.