Patent ID: 7189830
Filing Date: 2007-03-13
Classification: A61P,C07K

Abstract:
1. A modified fusion protein comprising an anti-KSA immunoglobulin moiety and an IL-2 polypeptide moiety linked together directly or through a linker peptide; wherein the anti-KSA immunoglobulin moiety comprises an anti-KSA immunoglobulin variable region polypeptide which comprises an amino acid residue sequence selected from the group consisting of SEQ ID NO: 660, SEQ ID NO: 661, SEQ ID NO: 662, SEQ ID NO: 663, SEQ ID NO: 664, SEQ ID NO: 665, SEQ ID NO: 666, SEQ ID NO: 667, SEQ ID NO: 668, SEQ ID NO: 669, SEQ ID NO: 676, SEQ ID NO: 677, SEQ ID NO: 678, SEQ ID NO: 679, SEQ ID NO: 680, SEQ ID NO: 681, SEQ ID NO: 682, SEQ ID NO: 683, SEQ ID NO: 684, and SEQ ID NO: 685.