Patent ID: 6126967
Filing Date: 2000-10-03
Classification: A61K,Y10S

Abstract:
An extended release acetaminophen composition comprising a plurality of discrete particles containing acetaminophen which, when contained within a gelatin capsule and assayed in a USP 23/NF 18 Apparatus I rotating basket at 50 rpm in 900 mL of phosphate buffer at pH 5.8 and 37.degree. C. exhibits about 40 percent to about 53 percent acetaminophen dissolution at one-half hour, about 50 percent to about 68 percent dissolution at 45 minutes, about 57 percent to about 77 percent acetaminophen dissolution at one hour, about 82 percent to about 92 percent acetaminophen dissolution at two hours and about 100 percent dissolution at six hours.