Patent ID: 6399093
Filing Date: 2002-06-04
Classification: A61K

Abstract:
A method for the treatment of musculoskeletal disorders in mammals by the application of a topical composition comprising:a) an effective amount of penetration enhancers selected from a group consisting of: alcohols, polyols, sulfoxides, esters, ketones, amides, oleates, surfactants, alkanoic acids, lactam compounds, alkalols, dialkylamino acetates, and b) anti-inflammatory bio-affecting agents, 0.1% to 25% by weight of the total composition, selected from a group comprising: nonsteroidal anti-inflammatory agents, and colchicine, in a therapeutically acceptable gel vehicle, so that, a means for the delivery of the bio-affecting agents through the protective outer layer of the skin, into the underlying tissues and into the vascular network of the targeted body part to reduce inflammation and provide relief.