Patent ID: 7868029
Filing Date: 2011-01-11
Classification: A61P,C07C,C07D

Abstract:
1. A process for the preparation of a 2-amino-4,5,6,7-tetrahydro-6-aminobenzothiazole 5a: or an enantiomer or a salt thereof, comprising the steps of: (a) reductively aminating a protected cyclohexandione 1p with an amine R wherein P is a protected ketone functionality, and wherein one of R (b) deprotecting the protected 4-amino-cyclohexanone 2p to yield an unprotected 4-amino-cyclohexanone 3a: (c) treating the unprotected 4-amino-cyclohexanone 3a with iodine and a thiourea H