Patent ID: 8088776
Filing Date: 2012-01-03
Classification: A61P,C07D

Abstract:
1. A compound structurally represented by the formula: wherein: R  wherein the dashed line represents the point of attachment to the R R R R R  wherein the dashed line represents the point of attachment to the R R HET  wherein the dashed line indicates the point of attachment to the position indicated by HET HET  wherein the dashed line indicates the point of attachment to the position indicated by HET R R R R R R R R R R R R provided the compound is not {[3′-Chloro-4′-(1-cyclohexyl-2-oxo-pyrrolidin-3-ylmethyl)-biphenyl-4-carbonyl]-amino}-acetic acid, 4-{[3′-Chloro-4′-(1-cyclohexyl-2-oxo-pyrrolidin-3-ylmethyl)-biphenyl-4-carbonyl]-amino}-butyric acid, 3′-Chloro-4′-(1-cyclohexyl-2-oxo-pyrrolidin-3-ylmethyl)-biphenyl-4-carboxylic acid piperidin-4-ylamide, or 3-[3-Chloro-4′-(4-methyl-piperazine-1-carbonyl)-biphenyl-4-ylmethyl]-1-cyclohexyl-pyrrolidin-2-one; or a pharmaceutically acceptable salt thereof.