Patent ID: 6358286
Filing Date: 2002-03-19
Classification: A61K,A61Q

Abstract:
A composition for the oxidation dyeing of keratin fibres comprising:at least one oxidation base, at least one cationic direct dye of formula (I) below: Aâ€”N&boxH;Nâ€”Bâ€ƒâ€ƒ(I) â€ƒwherein: A is chosen from structures A1, A2, and A3 below: â€ƒwherein in said structures A1 to A3: R1 is chosen from C1-C4 alkyl radicals, a phenyl radical, and phenyl radicals having a substituent chosen from C1-C4 alkyl radicals and halogen atoms chosen from chlorine, bromine, iodine and fluorine; R2 is chosen from C1â€”C4 alkyl radicals and a phenyl radical; R3 and R4, which may be identical or different, are chosen from C1-C4 alkyl radicals and a phenyl radical or together form a benzene ring having at least one substituent chosen from C1-C4 alkyl radicals, C1-C4 alkoxy radicals, and nitro radicals; R3 can also be a hydrogen atom; R5 and R6, which may be identical or different, are chosen from C1-C4 alkyl radicals and a phenyl radical or together form a benzene ring which is unsubstituted or has at least one substituent chosen from C1-C4 alkyl radicals, C1-C4 alkoxy radicals, and nitro radicals; R5 can also be a hydrogen atom; R7 and R8, which may be identical or different, are chosen from a hydrogen atom, halogen atoms chosen from chlorine, bromine, iodine and fluorine, C1-C4 alkyl radicals, C1-C4 alkoxy radicals and nitro radicals; Z is chosen from an oxygen atom, a sulphur atom, and a group NR2, wherein R2 is chosen from C1-C4 alkyl radicals and a phenyl radical; the ring member L is chosen from â€”CH, â€”CR and â€”N+R9(Xâˆ’)r; the ring member M is chosen from â€”CH, â€”CR and â€”N+R9(Xâˆ’)r; r is an integer equal to 0 or 1; R is chosen from C1-C4 alkyl radicals; R9 is chosen from an atom Oâˆ’, C1-C4 alkyl radicals, and C1-C4 alkoxy radicals; Xâˆ’ is chosen from an anion; â€ƒwith the provisos that: in said structure A3, at least one of the ring members L and M is a group â€”N+R9(Xâˆ’)r; when R6 is a C1-C4 alkyl radical and Z is a sulphur atom, then R5 is other than a C1-C4 alkyl radical; when R9 is Oâˆ’, then r=0; when L or M is a radical â€”N+R9(Xâˆ’)r wherein R9 is a C1-C4 alkyl radical and r=1, then at least one of the radicals R7 and R8 is other than a hydrogen atom; when L is a radical â€”N+R9(Xâˆ’)r, then M is chosen from â€”CH and CR; when M is a radical â€”N+R9(Xâˆ’)r, then L is chosen from â€”CH and CR; when Z is a group NR2 wherein R2 is a C1-C4 alkyl radical, then at least one of the radicals R1, R5 and R6 is other than a C1-C4 alkyl radical; B is chosen from: (a) a group of structure B1 below: â€ƒwherein in structure B1, R10 is chosen from a hydrogen atom, halogen atoms chosen from chlorine, bromine, iodine and fluorine, C1-C4 alkyl radicals, C1-C4 alkoxy radicals, a hydroxyl radical, â€”NHR13 groups, â€”NR14R15 groups, â€”NHCO(C1-C4)alkyl groups and a nitro, or forms with R11 a 5- or 6-membered carbon ring or a ring containing at least one hetero atom chosen from nitrogen, oxygen and sulphur; R11 is chosen from a hydrogen atom, halogen atoms chosen from chlorine, bromine, iodine and fluorine, C1-C4 alkyl radicals, and C1-C4 alkoxy radicals or forms with R12 or R13 a 5- or 6-membered carbon ring or a ring containing at least one hetero atom chosen from nitrogen, oxygen and sulphur; R12 is chosen from a hydrogen atom, a hydroxyl radical, â€”NHR13 radicals, and â€”NR14R15radicals; R13 is chosen from a hydrogen atom, C1-C4 alkyl radicals, C1-C4 monohydroxyalkyl radicals, C2-C4 polyhydroxyalkyl radicals, and a phenyl radical; R14 and R15, which may be identical or different, are chosen from C1-C4 alkyl radicals, C1-C4 monohydroxyalkyl radicals, and C2-C4 polyhydroxyalkyl radicals; â€ƒwith the provisos that when Z in structure A2 is a sulphur atom and R1 is a C1-C4 alkyl radical and when one of the radicals R10 and R11 in structure B1 is a hydrogen atom, then R5 and R6 cannot together form an unsubstituted benzene ring and when R6 in structure A2 is a C1-C4 alkyl radical and Z is a sulphur atom and when one of the radicals R10 and R11 in structure B1 is a hydrogen atom, then R5 is other than a hydrogen atom; and (b) a 5- or 6-membered nitrogenous heterocyclic group, a 5- or 6-membered nitrogenous heterocyclic group comprising at least one additional hetero atom chosen from oxygen and sulphur and/or at least one carbonyl group, wherein said heterocycles are unsubstituted or have at least one substituent chosen from C1-C4 alkyl, amino and phenyl radicals.