Patent ID: 8759335
Filing Date: 2014-06-24
Classification: A61P,C07D

Abstract:
1. A compound having formula I: or a pharmaceutically acceptable salt thereof, wherein: Ht is a 5-membered heteroaromatic ring containing 1-4 heteroatoms selected from O, S, or N, wherein Ht is optionally substituted with w occurrences of —WR R R is hydrogen or C ring A is a cyclopropyl ring, wherein ring A is optionally substituted with q occurrences of -QR x is 2, wherein the two R q is 0-4; each -Q-R Q , and —W—R w is independently R′; R′ is independently R 1 , R 2 , R 3 , R 4 , or R 5 ; R n is 0 or 1; Y is halo, CN, NO two R R R R R R R Z is selected from halo, CN, NO R