Patent ID: 6111101
Filing Date: 2000-08-29
Classification: C07D

Abstract:
An improved process for the preparation of 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine of formula (I) ##STR6## which process comprises the step of: (a) reacting 2,3-dichlorobenzoylchloride of formula (II) with cuprous cyanide in presence of acetonitrile and a cosolvent to produce dichlorobenzoyl cyanide (III) ##STR7## (b) reacting said dichlorobenzoyl cyanide (III) obtained in step (a) with aminoguanidine bicarbonate to produce the intermediate product of formula (IV) ##STR8## (c) cyclizing said intermediate of formula (IV) in presence of aqueous potassium hydroxide to produce 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine ##STR9##