Patent ID: 9127085
Filing Date: 2015-09-08
Classification: A61K,A61P,C07K

Abstract:
1. A fusion protein the sequence of which (a) is identical to the sequence of a portion of the extracellular domain of a human Notch1 receptor followed by (b) a sequence identical to the sequence of an Pc portion of an antibody, wherein the portion of the extracellular domain of the human Notch1 receptor is selected from the group consisting of EGF-like repeats 1-13, EGF-like repeats 1-24, EGF-like repeats 9-23, EGF-like repeats 9-16, EGF-like repeats 13-24 and EGF-like repeats 25-36, wherein (b) is located to the carboxy terminal side of (a), and wherein (b) is attached to (a) either directly or by means of a linker sequence.