Patent ID: 8545846
Filing Date: 2013-10-01
Classification: A61K,A61P,C07K,G06Q

Abstract:
1. A method of treating in a subject, a disease or condition selected from the group consisting of Type 2 diabetes, insulin resistance, decreased insulin production, and hyperglycemia, the method comprising administering to the subject one or more doses of an anti-IL-1β antibody or fragment thereof, wherein the antibody or fragment is administered in a dose of less than 0.01 mg/kg, and wherein said antibody or fragment thereof (i) comprises a light chain variable region of SEQ ID NO: 1 and a heavy chain variable region of SEQ ID NO: 2, or (ii) competes with the binding of an antibody comprising the light chain variable region of SEQ ID NO: 1 and the heavy chain variable region of SEQ ID NO: 2.