Patent ID: 7335751
Filing Date: 2008-02-26
Classification: A61P,C07C,C07K

Abstract:
1. An activated compound having a formula: wherein an activated moiety is attached to the hydroxyl group and wherein the activated moiety is selected from the group consisting of chloroformate, NHS carbonate, DSC para-nitrochloroformate, p-nitrochlorofomate, phosgene and paranitrophenyl carbonate, and where R n is 0-4; Olig is an oligomer having a formula: where: L is a optional linker moiety selected from the group consisting of —CH where: X is alkyl Y is N or O or is not present, and R PAG is a linear or branched polyalkylene glycol moiety; R q is a number from 1 to 10; and m is 1-5.