Patent ID: 6174681
Filing Date: 2001-01-16
Classification: C12Q

Abstract:
A method of screening for bladder cancer in a subject comprising:(a) hybridizing a set of chromosomal probes to a biological sample from said subject, wherein said set comprises at least three chromosomal probes selected from the group consisting of probes to chromosomes 3, 7, 8, 11, 15, 17, 18 and Y;(b) selecting cells from said biological sample based on abnormalities in nuclear morphology, nuclear size, or nuclear shape; and(c) determining the presence or absence of aneusomic cells in said selected cells by examining the hybridization pattern of said set of chromosomal probes in each of said selected cells,wherein the presence of aneusomic cells in said selected cells is indicative of bladder cancer in said subject.