Patent ID: 8492085
Filing Date: 2013-07-23
Classification: C12Q,H05K

Abstract:
1. An oligonucleotide array comprising: a support and a collection of double multimer unit oligonucleotides at different positions on the support so that complementary oligonucleotides to be immobilized on the support can be captured at the different positions, wherein the complementary oligonucleotides will hybridize, within a temperature range of greater than 24° C., to members of the collection of double multimer unit oligonucleotides, the double multimer unit oligonucleotides are formed from sets of four to eight tetramers where (1) each tetramer within a set differs from all other tetramers in the set by at least two nucleotide bases, (2) no two tetramers within a set are complementary to one another, and (3) no tetramers within a set are palindromic or dinucleotide repeats, and the collection of double multimer unit oligonucleotides has had the following oligonucleotides removed from it: (1) oligonucleotides having a melting temperature in ° C. less than 11 times the number of tetramers and more than 15 times the number of tetramers, (2) double multimer units with the same 3 tetramers linked together, and (3) double multimer units with the same 4 tetramers linked together with or without interruption.