Patent ID: 8435965
Filing Date: 2013-05-07
Classification: A61K,A61P

Abstract:
1. A method for suppressing adsorption of a basic chemical substance on a soft contact lens comprising: incorporating (B) at least one compound selected from the group consisting of L-glutamic acid and salts thereof, epsilon-aminocaproic acid and salts thereof, L-aspartic acid and salts thereof, chondroitin sulfate, a chondroitin polysulfate, and hyaluronic acid and salts thereof into a composition suitable for soft contact lenses including (A) a basic chemical substance selected from the group consisting of naphazoline, phenylephrine, neostigmine, diphenhydramine, tetrahydrozoline, pranoprofen, allantoin, and salts thereof, and (C) sterilized purified water; adjusting the pH of the composition including the components (A), (B) and (C) to 3.5 to 3.9, and adjusting a buffer power Q of the composition including the components (A), (B), and (C) to 5 to 18 ml, said Q being represented by the following equation: wherein QHCl is an amount (ml) of 0.1 mol/l of HCl necessary for lowering 100 g of the composition to a pH of 3.5, and QNaOH is an amount (ml) of 0.1 mol/l of NaOH necessary for raising 100 g of the composition to a pH of 7.5, at the pH measuring temperature of 20° C.