Patent ID: 6239127
Filing Date: 2001-05-29
Classification: A61P,C07D

Abstract:
A compound of formula I: ##STR16##whereR.sub.1 is (C.sub.1-6)alkyl or (C.sub.3-6)cycloalkyl;R.sub.2 is hydrogen or (C.sub.1-6)alkyl;X is (C.sub.1-12) alkylene; (C.sub.2-12) alkenylene; or (C.sub.2-12) alkynylene;m is 0 or 1; andR.sub.3 is (C.sub.3-8)cycloalkyl; or an aromatic ring system selected from II, III, IV and V: ##STR17##whereR.sub.4 is hydrogen, chloro, or methoxy;R.sub.5 is hydrogen, chloro, (C.sub.1-18)alkyl or (C.sub.1-18)alkoxy; and Z is oxygen, sulfur, N--H, or N--CH.sub.3 ;or a pharmaceutically acceptable acid addition salt thereof, where possible.