Patent ID: 9005923
Filing Date: 2015-04-14
Classification: C12N,C12P

Abstract:
1. A method of producing one or more compounds by fermentation comprising culturing a modified Candida bombicola strain to produce the one or more compounds, wherein said Candida bombicola strain has, compared to the unmodified wild-type strain: a) at least one deletion in an endogenous gene encoding an enzyme selected from the group consisting of the cytochrome P450 monooxygenase CYP52M1 having the sequence of SEQ ID NO: 67, the glucosyltransferase UGTA1 having sequence of SEQ ID NO: 2, and the glucosyltransferase UGTB1 having the sequence of SEQ ID NO: 4, and b) a reduction in its capability of producing sophorolipids of at least 75%, and wherein said sophorolipids are constituted of the sugar sophorose attached to a C