Patent ID: 6989437
Filing Date: 2006-01-24
Classification: A61K,A61L,A61Q,C07K,C08G,C08H,C08J,Y10S

Abstract:
1. A method for making a keratin network crosslinked by a multi-functional crosslinking agent comprising silicone, said method comprising exposing a plurality of α-keratin molecules comprising reactive pendant groups to said crosslinking agent under conditions effective to form covalent interprotein crosslinks between first reactive functionalities on said crosslinking agent and first reactive pendant groups on a first group of said α-keratin molecules, said conditions also being effective to form covalent interprotein crosslinks between second reactive functionalities on said crosslinking agent and second reactive pendant groups on a second group of α-keratin molecules, wherein said crosslinking agent has the following general structure: wherein n is from about 1 to about 50; and, at least two of R