Patent ID: 6201018
Filing Date: 2001-03-13
Classification: A61P,C07J,Y10S

Abstract:
A triterpene derivative represented by the following formula (III) or a salt thereof: ##STR23##whereinR.sup.1 representsa hydroxyl group,lower alkoxy, orlower alkanoyloxy;R.sup.2 represents--CH.sub.2 OR.sup.5, wherein R.sup.5 represents a hydrogen atom, arylmethyl, lower alkyl, or lower alkanoyl,Y represents a single bond to form a double bond in the ring with Y bonded thereto, andR.sup.27 represents--O--(CH.sub.2).sub.m --R.sup.22, whereinR.sup.22 representsamino,--NH--COOR.sup.23, wherein R.sup.23 represents arylmethyl or lower alkyl,a hydroxyl group,arylmethoxy, or--COOR.sup.24, wherein R.sup.24 represents a hydrogen atom, lower alkyl, or arylmethyl, andm is an integer of 1 to 4,--OCOCH(R.sup.25)(CH.sub.2).sub.n --R.sup.22, wherein R.sup.22 is as defined above,R.sup.25 represents a hydrogen atom, lower alkyl, aralkyl, or aryl, and n is an integer of 0 to 3,--OCON(R.sup.29)R.sup.30, wherein R.sup.29 and R.sup.30, which may be the same or different, represent a hydrogen atom, lower alkyl, lower alkanoyl, aryl, or aralkyl,--OCO--(CH.sub.2).sub.n --R.sup.16, wherein R.sup.16 represents a hydroxyl group, arylmethoxy, lower alkoxy, or lower alkanoyloxy, or--OCOCH.dbd.CH--COOR.sup.6, wherein R.sup.6 represents a hydrogen atom or lower alkyl.