Patent ID: 8445633
Filing Date: 2013-05-21
Classification: G01N

Abstract:
1. A peptide produced by chemical synthesis or recombinant expression having the ability to bind with adiponectin, wherein: (i) the peptide is a peptide consisting of the amino-acid sequence of any one of SEQ ID NOs: 1 to 15, 18 or 19; or (ii) the peptide is a peptide consisting of an amino-acid sequence in which one amino acid is substituted in the amino-acid sequence of any one of SEQ ID NOs: 1 to 15, and having the bindability with adiponectin; and the substitution of the amino acid in the peptide (ii) is conservative substitution between two amino acids selected from any one of the groups: (a) asparagine, glutamine, serine, threonine, and glycine; (b) asparaginic acid and glutamic acid; (c) histidine, lysine, and arginine; (d) alanine, isoleucine, leucine, proline, valine, and methionine; and (e) phenylalanine, tryptophan, and tyrosine.