Patent ID: 9024017
Filing Date: 2015-05-05
Classification: A61K,A61P,C07D

Abstract:
1. The compounds of Formula I wherein R R R H, —CN, C (1-4) alkyl, C (1-4) alkylNA 1 A 2 , C (1-3) alkylC(O)NA 1 A 2 , C (3-6) cycloalkyl, oxetan-3-yl, —(CH 2 ) n Ph-R aa , —C (1-4) alkylCO 2 C (1-4) alkyl, 4,5 dihydro thiazolyl, 4,5 dihydro oxazolyl, thiazolyl, oxazolyl, pyrimidinyl, pyridyl, pyrazyl, furyl, or 3-methyl 1,2,4 oxadiazol-5-yl; wherein said 4,5 dihydro thiazolyl, 4,5 dihydro oxazolyl, thiazolyl, oxazolyl, pyrimidinyl, pyridyl, pyrazyl, and furyl may be optionally substituted with up to two substituent independently selected from R aa , n is 0, 1, 2, or 3; R phenyl-R aa , oxazol-2-yl, oxazol-4-yl, isoxazol-5-yl, or thiazol-2-yl; R R R A A A R R R R Z Z and pharmaceutically acceptable salts thereof.