Patent ID: 7077871
Filing Date: 2006-07-18
Classification: A61K,A61Q

Abstract:
1. A method of reducing transcutaneous passage of an oxidation dye of a composition, comprising: a physiologically acceptable medium, at least one orthodiphenol oxidation dye, and at least one second oxidation dye, wherein the method comprises adding to the composition, a catalytic system comprising at least one first component selected from the group consisting of Mn(II) salt, Mn(II) oxide, Zn(II) salt, Zn(II) oxide, and combinations thereof, and at least one second component selected from the group consisting of alkaline hydrogencarbonate, alkaline earth hydrogencarbonate, and mixtures thereof, wherein at least one of the following equations are satisfied: where [Mn(II)], [Zn(II)]and [HCO (i) an oxidation base selected from the group consisting of ortho- and para-phenylenediamine, double base, ortho-aminophenol, para-aminophenol, heterocyclic base, acid addition salt thereof, and mixtures thereof; (ii) a para-phenylenediamine of the following formula: where: R R R R (iii) a double base selected from the group consisting of double bases having the formula (III): where: Z the linking arm Y represents a linear or branched alkylene chain comprising from 1 to 14 carbon atoms, which may be interrupted or terminated by one or more nitrogen groups and/or by one or more heteroatoms such as oxygen, sulfur or nitrogen atoms and optionally substituted by one or more C R R provided that the compounds of the formula (III) only comprise one linking arm Y per molecule (iv) an oxidation base is selected from the group consisting of one or more para-aminophenols of the formula (IV): where: R R (v) an orthoaminophenol selected from the group consisting of 2-amino-phenol, 2-amino-1-hydroxy-5-methyl-benzene, 2-amino-1-hydroxy-6-methyl-benzene, 5-acetamido-2-amino-phenol, acid addition salt thereof, and mixtures thereof; (vi) a heterocyclic base selected from the group consisting of pyridine derivate, pyrimidine derivate, pyrazole derivate, acid addition salt thereof, and mixtures thereof; and (vii) a coupling agent selected from the group consisting of meta-aminophenol, meta-phenylenediamine, metadiphenol, naphthol, heterocyclic coupling agent, indolic derivate, indolinic derivate, sesamol, sesamol derivate, pyridinic derivate, pyrazolotriazole derivate, pyrazolone, indazole, benzimidazole, benzothiazole, benzoxazole, 1,3-benzodioxole, quinoline, 2,4-diamino-1-(β-hydroxyethyloxy)benzene, 2-methyl-5-aminophenol, 5-N-(β-hydroxyethyl)amino-2-methylphenol, 3-aminophenol, 1,3-dihydroxybenzene, 1,3-dihydroxy-2-methylbenzene, 4-chloro-1,3-dihydroxybenzene, 2-amino-4-(β-hydroxyethylamino)-1-methoxybenzene, 1,3-diaminobenzene, 1,3-bis-(2,4-diaminophenoxy)propane, sesamol, 1-amino-2-methoxy-4,5-methylenedioxybenzene, α-naphthol, 6-hydroxyindole, 4-hydroxyindole, 4-hydroxy-N-methylindole, 6-hydroxyindolin, 2,6-dihydroxy-4-methylpyridine, 1-H-3-methylpyrazol-5-one, 1-phenyl-3-methylpyrazol-5-one, 2-amino-3-hydroxypyridine, 3,6-dimethyl-pyrazolo-[3,2-c]-1,2,4-triazole, 2,6-dimethyl-pyrazolo-[1,5-b]-1,2,4-triazole, acid addition salt thereof, and mixtures thereof.