Patent ID: 7943573
Filing Date: 2011-05-17
Classification: A61K,A61L,A61P,Y02A

Abstract:
1. A method of stimulating osteogenesis in a bone distraction procedure, wherein the osteogenesis stimulation consists of: applying an effective amount of a composition consisting of a platelet-derived growth factor (PDGF) solution disposed in a biocompatible matrix to at least one site of bone distraction, wherein the PDGF solution consists of PDGF in a buffer, wherein the PDGF is present in the solution in a concentration ranging from about 0.01 mg/ml to about 10 mg/ml, wherein the biocompatible matrix: (i) consists of a porous calcium phosphate, (ii) consists of collagen and a porous calcium phosphate, (iii) consists of an allograft, or (iv) consists of collagen and an allograft, wherein the calcium phosphate or allograft comprises interconnected pores, and wherein the calcium phosphate or allograft consists of particles in a range of about 100 to about 5000 microns in size.