Patent ID: 7790396
Filing Date: 2010-09-07
Classification: C12Q,G01N

Abstract:
1. A method for determining response to treatment with olanzapine for a human subject having or suspected of having schizophrenia comprising: determining the SULT4A1-1 haplotype in a sample, wherein the SULT4A1-1 haplotype is defined as a haplotype comprising a C allele at rs763120, a combination of an A allele at rs2285162 and a G allele at rs2285167, or the combination of a T allele at rs2285166 and G allele at rs2285167, and determining a response to treatment wherein if the human subject comprises the SULT4A1-1 haplotype the subject is more likely to exhibit a favorable response to olanzapine and if the subject does not comprise the SULT4A1-1 haplotype the subject is less likely to exhibit a favorable response to olanzapine.