Patent ID: 8114430
Filing Date: 2012-02-14
Classification: A61K

Abstract:
1. An implantable osmotic dosage form comprising: a pharmaceutical suspension comprising (i) particles comprising a protein or peptide, and (ii) a suspending vehicle comprising a polyoxaester having a density of about 1.2 g/mL, wherein the pharmaceutical suspension is substantially homogeneous for at least 3 months at 37° C.; a first wall that maintains its physical and chemical integrity and is substantially impermeable to a pharmaceutical suspension; a second wall that is partially permeable to an exterior fluid; an osmotic pump in contact with the first wall and the second wall; a compartment defined by the first wall and the osmotic pump, wherein the pharmaceutical suspension is positioned within the compartment; and an exit port in communication with the compartment, wherein the pharmaceutical suspension is flowable through the exit port under a force exerted by the osmotic pump.