Patent ID: 8153682
Filing Date: 2012-04-10
Classification: A61P,C07D

Abstract:
1. A compound of the formula (I) wherein A is CR B is CR G is S; Y is R R R R R R R R wherein R 13 is H, —C 1-4 alkyl, —CH 2 CO 2 CH 3 , —CH 2 NH(C 1-3 alkyl), —CH 2 N(C 1-3 alkyl) 2 , or —CH 2 CO 2 H; and R 14 is —C 6-10 aryl, —C 1-6 alkyl, —C 1-3 alkyl-OH, or —C 1-3 alkylCO 2 H; with the proviso that when R with the proviso that when R with the proviso that when R with the proviso that when Y is unsubstituted phenyl, and R with the proviso that Formula (I) is other than a compound wherein G is S, Y is H, R a compound wherein G is S, Y is 1-hydroxyethyl, R a compound wherein G is S, Y is methyl, R a compound wherein G is S, Y is methylcarbonylamino, R a compound wherein G is S, Y is H, R a compound wherein G is S, Y is bromo, R a compound wherein G is S, Y is methylaminocarbonyl, R a compound wherein G is S, Y is H, R a compound wherein G is S, Y is 4-methyl-piperazin-1-ylcarbonyl, R a compound wherein G is S, Y is bromo, R a compound wherein G is S, Y is dimethylaminomethyl, R a compound wherein G is S, Y is H, R a compound wherein G is S, Y is methylcarbonyl, R a compound wherein G is S, Y is H, R a compound wherein G is S, Y is H, R a compound wherein G is S, Y is methyl, R a compound wherein G is S, Y is H, R