Patent ID: 6803047
Filing Date: 2004-10-12
Classification: A61K,A61Q,Y10S

Abstract:
A topical composition comprising an aqueous gel which comprises a hydrophilic gelling material, wherein said gel has rheological properties comprising:an initial viscosity V0 ranging from 3000 to 50,000 Pa.s, wherein said initial viscosity V0 is stable up to a shear strain C1, a viscosity V2 after shear at a strain C2, wherein a ratio of V0/V2 is greater than or equal to 1000, and a difference of C2-C1 is less than or equal to 100 Pa; wherein said hydrophilic gelling material is a hydrophilic gelling polymer chosen from at least one water-soluble and water-dispersible terephthalic copolyester oligomer comprising dicarboxylate repeating units of formula (I):â€”COâ€”Aâ€”COâ€”Oâ€”(CH2â€”CH2â€”O)n-â€ƒâ€ƒ(I) whereinA is chosen from 1,4-phenylene and sulfo-1,3-phenylene groups, and optionally, 1,3-phenylene groups, n ranges from 1 to 4, at least 35 mol % of said units of formula (I) are units of formula (I) wherein A is a 1,4-phenylene group and n is equal to 1, at least 7 mol % of said units of formula (I) are units of formula (I) wherein A is a sulfo-1,3-phenylene group, and the weight-average molecular mass of said at least one copolyester oligomer is less than 20,000 polystyrene equivalents, as measured by gel permeation chromatography in dimethylacetamide containing 10âˆ’2 N of LiBr, at 100Â° C., and wherein said hydrophilic gelling material comprises from 0.5 to 15% by weight of the composition relative to the total weight of the composition.