Patent ID: 6180586
Filing Date: 2001-01-30
Classification: C11D

Abstract:
A liquid detergent composition comprising:a) a detersive effective amount of a detersive surfactant;b) an active proteolytic enzyme; andc) a peptide protease inhibitor having the formula:Z--A--NH--CH(R)--C(O)--Xwherein A is an amino acid moiety; X is hydrogen or CF.sub.3 ; Z is an N-capping moiety selected from the group consisting of phosphoramidate, sulfenamide, sulfonamide, sulfonic acid, phosphinamide, sulfamoyl derivative, thiourea, thiocarbamate, phosphonate, amidophosphate; and R is selected from the group consisting of straight or branched C.sub.1 -C.sub.6 unsubstituted alkyl phenyl, and C.sub.7 -C.sub.9 alkylaryl moieties; wherein the protease activity in the laundry detergent composition is less than 1% of the activity without the protease inhibitor, and the ratio of the percent of free protease in the wash to the percent of free protease in the laundry detergent composition is greater than 100.