Patent ID: 6774239
Filing Date: 2004-08-10
Classification: C07D

Abstract:
A process for the preparation of azolide salts of the formula (II) whereinX1, X2, and X3 independently of one another are each CR1 or nitrogen, where R1 is hydrogen or C1-C5-alkyl, and R2 is hydrogen, or X2 is as defined above, and X1 and X3 are CR1, where the R1 of each X1 is hydrogen or C1-C6-alkyl, and the R1 of each X3, together with R2 of the same diazole ring, forms a â€”CH&boxH;CHâ€”CH&boxH;CHâ€” bridge; M is an equivalent of an alkali metal or alkaline earth metal cation or a quaternary onium ion of the formula (III) [YR3R4R5R6]â€ƒâ€ƒ(III), whereinY is phosphorus or nitrogen, and R3, R4, R5, and R6 independently of one another are each C1-C20-alkyl, phenyl, benzyl, or ethylbenzyl; comprising reacting (1) an azole of the formula (IV) â€ƒin which X1, X2, X3, and R2 are as defined for the formula (II), with (2) a compound of the formula (V) Mâ€²R7â€ƒâ€ƒ(V) whereinMâ€² is an equivalent of an alkali metal or alkaline earth metal but is not a quaternary onium ion of the formula (III) and R7 is OR9, where R9 is H or Methyl in a solvent, wherein the solvent is an aromatic compound or ether or a mixture thereof with a solvent of the formula (VII)HR7â€ƒâ€ƒ(VII), in which R7 is as defined above and whereby the solvent of formula (VII) that is introduced or formed during the reaction is removed by distillation.