Patent ID: 6821507
Filing Date: 2004-11-23
Classification: A61K,A61P,A61Q

Abstract:
An oral composition having antimicrobial activity effective for reducing plaque and gingivitis, said composition comprising:a. a stannous ion source that comprises a stannous salt other than stannous fluoride or stannous monofluorophosphate and is capable of delivering from about 3,000 ppm to about 15,000 ppm stannous ions, b. a fluoride ion source, and c. a polymeric surface active agent, which is a polyelectrolyte selected from the group consisting of condensed phosphorylated polymers; polyphosphonates; carboxy-substituted alcohol polymers; copolymers of phosphonate- or phosphonate-containing monomers or polymers with ethylenically unsaturated monomers, amino acids, or with other polymers selected from proteins, polypeptides, polysaccharides, poly(acrylate), poly(acrylamide), poly(methacrylate), poly(ethacrylate), poly(hydroxyalkylmethacrylate), poly(vinyl alcohol), poly(maleic anhydride), poly(maleate) poly(amide), poly(ethylene amine), poly(ethylene glycol), poly(propylene glycol), poly(vinyl acetate) or poly(vinyl benzyl chloride); and mixtures thereof, wherein said polymeric surface active agent binds stannous ions.