Patent ID: 6726624
Filing Date: 2004-04-27
Classification: A61B

Abstract:
A method for determining the appropriate dosage of a medication to treat Attention Deficit Hyperactivity Disorder (ADHD) in an individual who has ADHD comprising:(a) sampling the peripheral skin temperature of left and right like extremities of an individual during a predetermined time interval when the subject is in a sensory deprived state to provide respective left and right sampled peripheral skin temperature data; (b) a first processing of at least one of said left and right sampled peripheral skin temperature data providing conversion to the frequency domain to derive a first spectral signature having magnitude values; (c) a second processing of both said left and right sampled peripheral skin temperature data to derive temporally correlated differential data; (d) said second processing further filtering said differential data with a high pass filter to produce filtered differential data with near d. c. components removed; (e) said second processing lastly providing conversion to the frequency domain of said filtered differential data to derive a second spectral signature having magnitude values; (f) a third processing of the said first spectral signature for the determination of the level of manifestation of ADHD by comparison to a predetermined first threshold value; (g) a fourth processing of the said second spectral signature for the determination of the level of manifestation of ADHD by comparison to a predetermined threshold value; and (h) a fifth processing wherein an assessment of the bi-modal quality of the results of the third and fourth processing is made, to provide a final determination of one of the following three possibilities: (i) a various level of dosage change; (ii) dosage level is adequate; (iii) there is noise in the data.