Patent ID: 6863886
Filing Date: 2005-03-08
Classification: A61K,Y10S

Abstract:
1. A method for inducing liquefaction of a vitreous humor to treat a disorder of a mammalian eye, said method comprising contacting with said vitreous humor of said mammalian eye an amount of hyaluronidase effective to liquefy said vitreous humor whereby said disorder is treated, wherein said hyaluronidase is defined as being free of thimerosal, and essentially devoid of hyaluronidase molecular weight fractions above 100,000, between 50,000 and 60,000, and below 20,000 as determined by 4-20% Gradient SDS PAGE electrophoresis, and wherein said hyaluronidase is defined as causing hydrolysis of the endo-N-acetyl hexosaminic bonds of hyaluronic acid.