Patent ID: 8506987
Filing Date: 2013-08-13
Classification: A61F,A61K,A61P

Abstract:
1. A method for treating a medical condition of the eye comprising implanting into an ocular region of the eye a bioerodible implant and delivering a therapeutic amount of an active agent to the ocular region, wherein a) the bioerodible implant is a double extruded rod comprising an active agent homogeneously dispersed within a biodegradable polymer matrix; wherein b) the biodegradable polymer matrix comprises a mixture of hydrophilic ended poly(D,L-lactide-co-glycolide) (PLGA) and hydrophobic ended poly(D,L-lactide-co-glycolide) (PLGA); wherein the hydrophilic- and hydrophobic-end PLGAs are milled prior to extrusion with the active agent; wherein c) the bioerodible implant is sized for implantation in an ocular region; and wherein d) the medical condition of the eye is selected from the group consisting of uveitis, macular edema, macular degeneration, retinal detachment, ocular tumors, fungal infections, viral infections, multifocal choroiditis, diabetic retinopathy, proliferative vitreoretinopathy (PVR), sympathetic ophthalmia, Vogt Koyanagi-Harada (VKH) syndrome, histoplasmosis, uveal diffusion, and vascular occlusion.