Patent ID: 8324243
Filing Date: 2012-12-04
Classification: A61K,A61P,C07D

Abstract:
1. A compound of formula (I): the group —CH one of the radicals R a hydrogen atom, a C or one of the radicals R in which R X or Y represents a hydrogen atom, a C the other of the radicals R or, when one of the groups R or, when one of the groups R or R or R with the exclusion of 5-((benzylamino)methyl)quinolin-8-ol, and 5-((1,4,8,12-tetraazacyclopentadecan-8-yl)methyl)quinolin-8-ol, tri-tert-butyl 12-((8-hydroxyquinolin-5-yl)methyl)-1,4,8,12-tetraazacyclopentadecane-1,4,8-tricarboxylate, tri-tert-butyl 11-((8-hydroxyquinolin-5-yl)methyl)-1,4,8,11-tetraazacyclotetradecane-1,4,8-tricarboxylate, 5-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)quinolin-8-ol, tri-tert-butyl 11-(3-((4,11-bis(tert-butoxycarbonyl)-8-((8-hydroxyquinolin-5-yl)methyl)-1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzyl)-1,4,8,11-tetraazacyclotetradecane-1,4,8-tricarboxylate, 5,5′-(propane-1,3-diylbis(azanediyl))bis(methylene)-diquinolin-8-ol, 5-((8-(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzyl)-1,4,8,11-tetraazacyclotetradecan-1-ylmethyl)quinolin-8-ol, di-tert-butyl 4,8-bis((8-hydroxyquinolin-5-yl)methyl)-1,4,8,11-tetraazacyclotetradecane-dicarboxylate, 5,5′-(1,4,8,11-tetraazacyclotetradecane-1,1′-diyl)bis(methylene)diquinolin-8-ol, 5,5′-(1,4-phenylenebis(methylene))bis(azanediyl)-bis(methylene)diquinolin-8-ol, 5-(((8-hydroxyquinolin-5-yl)(4-methylbenzyl)amino)-methyl)quinolin-8-ol, tert-butyl 8-hydroxyquinolin-5-yl(4-methylbenzyl)-carbamate, 5-((4-methylbenzylamino)methyl)quinolin-8-ol, 5-(naphthalen-1-ylmethylamino)quinolin-8-ol, 5,5′-(naphthalen-1-ylmethylazanediyl)diquinolin-8-ol, tert-butyl 8-hydroxyquinolin-5-yl(naphthalen-1-ylmethyl)carbamate, and 5-(((8-hydroxyquinolin-5-yl)(4-(trifluoromethyl)benzyl)amino)methyl)quinolin-8-ol.