Patent ID: 6531580
Filing Date: 2003-03-11
Classification: A61K,A61P,C07K

Abstract:
An antibody, or functional fragment thereof, comprising a VH CDR1 referenced as SEQ ID NO:34; a VH CDR2 referenced as SEQ ID NO:102; a VH CDR3 referenced as SEQ ID NO:106; a VL CDR1 referenced as SEQ ID NO:108; a VL CDR2 referenced as SEQ ID NO:112; and a VL CDR3 referenced as SEQ ID NO:90, said antibody or functional fragment thereof having integrin &agr;V&bgr;3 binding activity, integrin &agr;V&bgr;3 binding specificity or integrin &agr;V&bgr;3-inhibitory activity.