Patent ID: 8224640
Filing Date: 2012-07-17
Classification: G06T,G16H

Abstract:
1. A method for multi-component heart modeling and cardiac disease decision support, comprising: generating a multi-component patient specific 4D geometric model of the heart and aorta estimated from a sequence of volumetric cardiac imaging data of a patient generated using at least one medical imaging modality; generating a patient specific 4D computational model based on one or more of personalized geometry, material properties, fluid boundary conditions, and flow velocity measurements in the 4D geometric model; and estimating patient specific material properties of an aortic wall using the 4D geometrical model and the 4D computational model by determining parameters of a constitutive material model of the aortic wall to minimize a residue between a simulated deformation of the aortic wall determined based on a Fluid Structure Interaction (FSI) simulation and a measured deformation of the aortic wall in the 4D geometric model.