Patent ID: 7045139
Filing Date: 2006-05-16
Classification: A61K,C07C

Abstract:
1. A process for preparing cinnamidoalkylamine and/or benzamidoalkylamine quaternary compounds of Formula I, wherein; ArCO is selected from p-N,N-dimethylamino benzoyl or p-methoxy cinnamoyl; R R R n is an integer having values from 1 to 6, the process comprising steps of (i) quaternisation of 1.0 mole of cinnamidoalkylamine and/or benzamidoalkylamine of Formula II with 1.0 mole of alkylating compound of Formula III, wherein, R (ii) treating the aqueous solution of quaternary halide of Formula IV obtained in step (i) with stoichiometric quantities of sodium p-toluene sulphonate to get water insoluble quaternary ammonium tosylate of Formula I.