Patent ID: 6037474
Filing Date: 2000-03-14
Classification: C07D

Abstract:
Process for the preparation of a cyclic 4-oxoamidine of the formula I ##STR7## or addition salts thereof with organic and inorganic acids whereinR.sup.1 and R.sup.2 may be the same or different represent:H,linear or branched chain substituted or unsubstituted (C.sub.1 -C.sub.8)-alkyl, C.sub.2 -C.sub.8)-alkenyl, (C.sub.2 -C.sub.8)-alkynyl, (C.sub.1 -C.sub.8)-alkoxy, (C.sub.2 -C.sub.8)-alkoxyalkyl, wherein the substituents are selected from the group consisting of mono- or poly-halogens and radicals containing N, O, P atoms,saturated or unsaturated substituted or unsubstituted (C.sub.3 -C.sub.7)-cycloalkyl, wherein the substituents are selected from the group consisting of linear or branched (C.sub.1 -C.sub.8)-alkyl, (C.sub.2 -C.sub.8)-alkenyl, (C.sub.1 -C.sub.8)-alkoxy, (C.sub.2 -C.sub.8)-alkoxyalkyl, halogens and radicals containing N, O, P atoms,saturated or unsaturated substituted or unsubstituted (C.sub.3 -C.sub.7)-hetero-cycloalkyl, wherein the substituents are selected from the group consisting of linear or branched (C.sub.1 -C.sub.8)-alkyl, (C.sub.2 -C.sub.8)-alkenyl, (C.sub.1 -C.sub.8)-alkoxy, (C.sub.2 -C.sub.8)-alkoxyalkyl, halogens and radicals containing N, O, P atoms, wherein the hetero moieties in said cycloalkyl groups are selected from the group consisting of N, O, P atoms,mono and poly substituted and unsubstituted aryl, aralkyl, heteroaryl, heteroaralkyl, wherein the substituents are selected from the group consisting of linear or branched (C.sub.1 -C.sub.8)-alkyl, (C.sub.2 -C.sub.8)-alkenyl, (C.sub.1 -C.sub.8)-alkoxy, (C.sub.2 -C.sub.8)-alkoxyalkyl, halogens and radicals containing N, O, P atoms,provided however that R.sup.1 and R.sup.2 when bonded together as shown in phantom and taken together with the carbon atom to which both are linked form a mono or poly substituted or unsubstituted 3- to 7-membered carboxcyclic or heterocyclic, saturated or unsaturated ring, wherein the substituents are selected from the group consisting of linear or branched (C.sub.1 -C.sub.8)-alkyl, (C.sub.2 -C.sub.8)-alkenyl, (C.sub.1 -C.sub.8)-alkoxy, (C.sub.2 -C.sub.8)-alkoxyalkyl, halogens and radicals containing N, O, P atoms,R.sup.3, R.sup.4, R.sup.5, each independently of the others, have the meanings given for R.sup.1, with the proviso that R.sup.3 and R.sup.5 are not simultaneously other than H and the radicals of the group R.sup.3, R.sup.4 or R.sup.5 are not bonded together to form a ring,n is an integer from 1 to 3,which comprises subjecting to oxidising conditions,a ring compound of the formula II ##STR8## or a salt thereof.