Patent ID: 6271231
Filing Date: 2001-08-07
Classification: C07D,C07H

Abstract:
A compound of formula (IA): ##STR7##wherein X, Y, Z, and A is each independently carbon;R.sub.1, R.sub.2, R.sub.3, and R.sub.4 is each independently H, amino, nitro, halo, C.sub.1-6 alkyl, phenylC.sub.1-6 alkyl, C.sub.1-6 alkoxy, haloC.sub.1-6 alkyl, C.sub.1-6 alkoxycarbonyl, or absent when the atom to which it would be attached is nitrogen;R.sub.5 and R.sub.6 is each independently H, C.sub.1-6 alkyl, hydroxyC.sub.1-6 alkyl, aminoC.sub.1-6 alkyl, phenylC.sub.1-6 alkyl, carboxyC.sub.1-6 alkyl, C.sub.2-6 alkenyl, (phenylC.sub.1-3 alkoxy)C.sub.1-3 alkyl, (C.sub.1-6 acyloxy)C.sub.1-6 alkyl, (C.sub.1-6 alkoxycarbonyl)C.sub.1-6 alkyl, (mono- or di-C.sub.1-6 alkyl)aminoC.sub.1-6 alkyl, (C.sub.1-6 alkyl)aminocarbonylC.sub.1-6 alkyl, (C.sub.1-6 acylamino)C.sub.1-6 alkyl, (aminoC.sub.1-3 alkylphenyl)C.sub.1-3 alkyl, or aminodeoxyhexopyranosyl;R.sub.7 and R.sub.8 is each independently H, amino, nitro, hydroxy, halogen, C.sub.1-6 alkoxy, phenylC.sub.1-6 alkoxy or C.sub.1-6 alkoxycarbonyl;R.sub.9 is H, C.sub.1-6 alkyl, phenyl, halophenyl or phenylC.sub.1-6 alkyl;or a pharmaceutically acceptable salt thereof,with the proviso that:3-(1H-indol-3-yl)-1H-quinoxalin-2-one,3-(2-methyl-1H-indol-3-yl)-1H-quinoxalin-2-one, and3-(1,2-diphenyl-1H-indol-3-yl)-1H-quinoxalin-2-oneare excluded.