Patent ID: 6147097
Filing Date: 2000-11-14
Classification: A61P,C07D

Abstract:
A compound selected from the group consisting of an imidazole compound of the formula (I') or a pharmaceutically acceptable salt thereof: ##STR11## wherein R.sup.1 represents an alkyl group of 1 to 20 carbon atoms, an alkenyl group of 2 to 7 carbon atoms, a cycloalkylalkyl group of 4 to 12 carbon atoms, a haloalkyl group of 1 to 6 carbon atoms, an oxoalkyl group of 1 to 6 carbon atoms, an aroylalkyl group of 8 to 13 carbon atoms, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted heteroarylalkyl group, a substituted or unsubstituted carbamoyloxyalkyl, carbamoylalkyloxyalkyl, or acyloxyalkyl group, or a branched hydroxyalkyl group, provided that R.sup.1 does not represent a substituted or unsubstituted biphenylalkyl group;R.sup.2 represents an alkyl group of 1 to 6 carbon atoms, an acyl group of 1 to 6 carbon atoms, hydroxyiminomethyl, hydrazonomethyl, or a group of the formula --(CH.sub.2).sub.n --R.sup.4 wherein R.sup.4 represents halogen, an alkoxy group, hydroxy, cyano, an acyloxy group, an aryloxycarbonyloxy group, an alkoxycarbonyloxy group, carboxy, a substituted or unsubstituted carbamoyl group, a substituted or unsubstituted hydroxyalkyloxy group, a substituted or unsubstituted benzyloxy group, a substituted carbamoyloxy or thiocarbamoyloxy group, a substituted or unsubstituted amino group, or azido and n represents a whole number of 1 to 3, wherein R.sup.2 represents a group other than alkyl groups, either when Z is CH.sub.2, or when both X and Y are hydrogen;R.sup.3 represents a substituted or unsubstituted alkyl group of 1 to 6 carbon atoms;X and Y independently represent hydrogen, an alkyl group of 1 to 3 carbon atoms, halogen, or nitro; andZ represents S, SO, SO.sub.2 or CH.sub.2.