Patent ID: 8188080
Filing Date: 2012-05-29
Classification: A61K,A61P,C07D

Abstract:
1. A method of treating cancer comprising administering to a patient in need of one or more compounds, or pharmaceutically acceptable salts thereof, having the formula: wherein A is phenyl or a heteroaryl or heterocyclic ring having from 5 to 10 ring atoms that can be further substituted by one or more R units; each R is independently chosen from: i) alkyl, alkenyl, or alkynyl; ii) aryl; iii) heterocyclic; or iv) heteroaryl; that can be further substituted by one or more organic radicals; L X Y Y L is a linking group containing 1 to 3 carbon atoms; and Z is a keto, sulfonic acid, sulfonamide, alkylsulphonamide, phosphonic acid, or phosphonic ester radical, wherein the cancer is breast cancer, cervical cancer, ovarian cancer, leukemia cancer, hepatic cancer, nephritic cancer, pancreatic cancer, brain cancer, or lung cancer.