Patent ID: 7468434
Filing Date: 2008-12-23
Classification: A61K,A61P

Abstract:
1. A method for protecting against the degeneration of retinal ganglion cells caused by an eye disease in a subject comprising: (a) providing a photosensitive aza-crown ether or crown ether of a chromene or a diazene compound that releases lithium upon exposure to light; (b) administering an effective amount of the aza-crown or crown ether of a chromene or a diazene compound in a pharmaceutically acceptable carrier to the eye of the subject; and (c) exposing the eye of the subject to an external light source to cause the aza-crown ether or crown ether of a chromene or a diazene compound to release lithium wherein the photosensitive aza-crown ether or crown ether moiety of a chromene or diazene compound has one of the following structures: