Patent ID: 6137290
Filing Date: 2000-10-24
Classification: G01R

Abstract:
A method of magnetic resonance spectroscopic imaging with reduced chemical shift error comprising the steps of:a) placing an object to be imaged in a magnetic field;b) applying selective out of volume saturation pulses at frequencies outside of the volume of interest thereby suppressing any subsequent generation of signal from outside the volume of interest, said selective out of volume saturation pulses being formed by:(i) providing data des (.omega.) which indicates a desired pulse profile;(ii) calculating an initial weighting function W (.omega.);(iii) calculating a set of SLR polynomials using a weighted least mean squares process, the desired pulse profile des (.omega.); andiv) producing the RF pulse envelope R(t) by performing an inverse SLR transformation using the calculated SLR polynomials,c) applying a pulse sequence to selectively excite a slice or volume larger than the volume of interest such that the volume of interest is excited by a passband common to all desired chemical shift frequencies; andd) detecting a signal from the chemical shift insensitive volume of interest.