Patent ID: 7996155
Filing Date: 2011-08-09
Classification: G16B

Abstract:
1. A method of analyzing a plurality of measurements of a biological variable {y ti } in k different measurement groups by ANOVA analysis to determine whether there are differences among said k different measurement groups, wherein the biological variable is a transcript level of a gene measured using a microarray or an abundance of a protein measured using a protein microarray or two-dimensional gel electrophoresis, wherein y ti is the ith measurement in the tth measurement group, t=1, 2, . . . , k and i=1, 2, . . . , n t , n t being the number of measurements in the tth measurement group, wherein each said measurement group consists of n t measurements of said biological variable under a condition common to said measurement group, and wherein each said measurement y ti has a predetermined measurement variance σ ti 2 , said method comprising on a computer (a) determining, by the computer, a within-group variance for said k different measurement groups, wherein said within-group variance consists of a propagated variance and a scattered variance, said propagated variance being determined based on said predetermined measurement variances {σ and wherein said measurement group scattered variance σ wherein said predetermined measurement variances {σ