Patent ID: 6136972
Filing Date: 2000-10-24
Classification: C07C,C07D

Abstract:
A method for preparing an alkyl 2-[2-(secondary amino methyl)-5-alkylphenoxy]-alkanoate comprising the steps in the order given:(A) reacting a first mixture of (1) m-alkyl phenol, (2) a secondary amine, and (3) an aldehyde with or without a catalyst in a first solvent at reflux temperatures to form a 2-[(secondary amino)methyl]-5-alkylphenol; and(B) reacting a second mixture of the 2-[(secondary amino)methyl]-5-alkylphenol, (4) an alkyl 2-haloalkanoate, and (5) an alkali metal carbonate with or without a second catalyst in a second solvent at reflux temperatures to form the alkyl 2-[2-(secondary amino methyl)-5-alkylphenoxy]-alkanoate.