Patent ID: 8299035
Filing Date: 2012-10-30
Classification: A61P,C07H

Abstract:
1. A 10a-azalide compound represented by the formula (I): wherein, in the formula, R a hydroxyl group, a protected hydroxyl group, a group represented by the formula —X one of R a hydrogen atom, a hydroxyl group, a protected hydroxyl group, an amino group, a protected amino group, a group represented by the formula —X a group represented by the formula —X a group represented by the formula —X a group represented by the formula —X one of R a group represented by the formula —X a group represented by the formula —X a group represented by the formula —X R an oxime group, a protected oxime group, a group represented by the formula 3: a group represented by the formula 4: or a group represented by the formula 5: R a hydrogen atom, a group represented by the formula —R a group represented by the formula —CH a group represented by the formula —CH R one of R a hydrogen atom, a hydroxyl group, a protected hydroxyl group, an amino group, a protected amino group, a group represented by the formula —X a group represented by the formula —X R an oxo group, an oxime group, a protected oxime group, a group represented by the formula ═N—X a group represented by the formula ═N—X R a hydrogen atom, or a protective group of hydroxyl group, R a hydrogen atom, a C a protective group of an amino group, X a single bond, a group represented by the formula —O—, a group represented by the formula —OCO—, a group represented by the formula —OCO a group represented by the formula —OCON(R a group represented by the formula —S(O) a group represented by the formula —SO a group represented by the formula —OCS—, a group represented by the formula —CO—, a group represented by the formula —CO a group represented by the formula —CON(R a group represented by the formula —CH═N—, a group represented by the formula —CH═N—O—, a group represented by the formula —C(R a group represented by the formula —C(R a group represented by the formula —C(R a group represented by the formula —CH═N—N(R a group represented by the formula —CS—, a group represented by the formula —C(S)O—, a group represented by the formula —CSN(R a group represented by the formula —O—N═C(R a group represented by the formula —N═CH—, a group represented by the formula —N(R a group represented by the formula —N(R a group represented by the formula —N(R a group represented by the formula —N(R a group represented by the formula —N(R a group represented by the formula —N(R A a divalent C an arylene group which may be substituted with a hydroxyl group or a C a divalent heterocyclic group which may be substituted with a hydroxyl group or a C R a hydrogen atom, or a C