Patent ID: 8551452
Filing Date: 2013-10-08
Classification: A61K,G01R

Abstract:
1. A method of evaluating a subject's compliance with a uridine dietary supplementation regimen comprising: administering a uridine dietary supplement to a subject according to a regimen; determining said subject's brain cytidine-containing compound level via in vivo magnetic resonance spectroscopy (MRS) by selecting a brain region of interest where increased cytidine-containing compounds occur optionally using MRI prior to MRS; isolating a volume of interest (VOI) within the brain region of interest; defining the voxel size of the VOI; and using localized proton MRS, quantifying the levels of cytidine-containing compounds inside the VOI; and using said brain cytidine-containing compound level to evaluate the subject's compliance with the uridine dietary supplementation regimen, wherein the magnetic resonance spectroscopy is of