Patent ID: 9034614
Filing Date: 2015-05-19
Classification: C07C,C12P

Abstract:
1. A method of preparing alkyl butyrate, comprising: (a) producing a broth including a butyrate salt via fermentation using a butyric acid production strain; (b) converting the butyrate salt in the broth into butyric acid by supply of carbon dioxide and simultaneously extracting butyric acid from the broth using an extraction solvent in a continuous extraction apparatus, to obtain an extract containing butyric acid, wherein the continuous extraction apparatus is configured such that an extraction column is provided with a plurality of plates which perform a reciprocating motion vertically, and the broth and the extraction solvent are respectively supplied to upper and lower portions of the extraction column; and (c) reacting the extract with an alcohol having 4 or less carbons or a mixture thereof using an esterification reactor to obtain alkyl butyrate, wherein an interface between a broth layer and an extraction solvent layer in the extraction column is maintained below the middle position of the extraction column, and wherein in step (b), carbon dioxide is supplied to a lower portion of the extraction solvent layer in the extraction column, and the interface between the extraction solvent layer and the broth layer is below a position at which carbon dioxide is supplied.