Patent ID: 6393310
Filing Date: 2002-05-21
Classification: A61B

Abstract:
A method for the in-vivo determination of the relative individual percentages of a plurality of hemoglobin species comprising:generating a spectrophotometric data measurement by measuring a spectrophotometric property of light at a plurality of wavelengths in capillary bed tissue said plurality of wavelengths ranging from 510 to 620 nm and including: at least one analyte wavelength for a hemoglobin species; at least one analyte wavelength for at least a second hemoglobin species; a first reference wavelength; and a second reference wavelength; calculating the difference in the spectrophotometric property at the first reference wavelength and the second reference wavelength to define a difference term; normalizing the spectrophotometric measurement at each analyte wavelength utilizing the ratio of the spectrophotometric measurement at the analyte wavelength to the difference term; and determining relative percentages of the hemoglobin species.