Patent ID: 9005630
Filing Date: 2015-04-14
Classification: A61K,C07K

Abstract:
1. A fusion protein comprising a first peptide and a second peptide linked together with a linker, wherein the first peptide is an allergen and the second peptide is a FGL-2 C-terminal peptide selected from the group consisting of amino acids 23-122 of SEQ ID NO:1 and sequences with at least 95% identity to amino acids 23-122 of SEQ ID NO:1, and wherein said FGL-2 C-terminal peptide selected from the group consisting of amino acids 23-122 of SEQ ID NO:1 and sequences with at least 95% identity to amino acids 23-122 of SEQ ID NO:1 binds to human B-cells with a greater affinity than full-length FGL2.