Patent ID: 7060683
Filing Date: 2006-06-13
Classification: A61P,C07C

Abstract:
1. A method for the treatment of stroke comprising administering to a subject in need of such treatment an effective amount of a compound of the Formula I: wherein: W is A-B-D; A is aryl(CH B is a bond or CO, SO, SO D is a bond, an amino acid residue, or a peptide composed of 2 to 5 amino acid residues, said amino acid residue(s) being independently defined by the formula —NH-**CH(R n is an integer from 0 to 6; R J is halogen, lower alkyl, aryl, heteroaryl, haloaryl, amino optionally substituted with one to three aryl or lower alkyl groups, guanidino, alkoxycarbonyl, amido, lower alkylamido, sulfonamido, lower alkyl sulfonamido, lower alkylsulfonyl, lower alkylsulfoxy, lower alkylthio, lower alkoxy, aryloxy, arylalkyloxy, hydroxy, carboxy, cyano, or nitro; and * denotes the α carbon of an α-amino acid residue possessing, when R