Patent ID: 6090162
Filing Date: 2000-07-18
Classification: A61K,A61Q

Abstract:
A composition for the oxidation dyeing of keratinous fibres, in an appropriate medium for dyeing, said composition comprising:an oxidation base, said oxidation base being a 5-substituted 3,4-diaminopyrazole of formula I or an acid addition salt thereof: ##STR6## in which: R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are identical or different and represent a hydrogen atom; a linear or branched C.sub.1 -C.sub.6 alkyl radical; a C.sub.2 -C.sub.4 hydroxyalkyl radical; a C.sub.2 -C.sub.4 aminoalkyl radical; a phenyl radical; a phenyl radical substituted with a halogen atom or a C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, nitro, trifluoromethyl, amino or C.sub.1 -C.sub.4 alkylamino radical; a benzyl radical; a benzyl radical substituted with a halogen atom or with a C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, methylenedioxy, hydroxyl, C.sub.1 -C.sub.4 hydroxyalkyl, amino or C.sub.1 -C.sub.4 alkylamino radical;at most one of the radicals R.sub.2 to R.sub.5 represents a radical ##STR7## in which m and n are integers that are identical or different and range from 1 to 3 inclusive,X represents an oxygen atom or the group NH,Y represents a hydrogen atom or a methyl radical, andZ represents a methyl radical, an OR or NRR' group in which R and R' are identical or different and represent a hydrogen atom, a methyl radical or an ethyl radical;with the proviso that when R.sub.2 represents a hydrogen atom, R.sub.3 may also represent an amino or C.sub.1 -C.sub.4 alkylamino radical;R.sub.6 represents a linear or branched C.sub.1 -C.sub.6 alkyl radical; a C.sub.1 -C.sub.6 alkoxyradical; a C.sub.1 -C.sub.4 hydroxyalkyl radical; C.sub.1 -C.sub.4 hydroxyalkylamino radical; a C.sub.1 -C.sub.4 aminoalkyl radical; a phenyl radical; a phenyl radical substituted with a halogen atom or with a C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, nitro, trifluoromethyl, amino or C.sub.1 -C.sub.4 alkylamino radical; a benzyl radical; a benzyl radical substituted with a halogen atom or with a C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, nitro, trifluoromethyl, amino or C.sub.1 -C.sub.4 alkylamino radical; a heterocycle selected from thiophene, furan and pyridine; or a radical --(CH.sub.2).sub.p --O--(CH.sub.2).sub.q --OR"", in which p and q are integers that are identical or different and range from 1 to 3 inclusive and R"" represents a hydrogen atom or a methyl radical,with the proviso that in the formula I above:at least one of the R.sub.4 and R.sub.5 radicals represents a hydrogen atom, andwhen R.sub.2 represents a substituted or unsubstituted phenyl radical, a benzyl radical or a radical ##STR8## then R.sub.3 does not represent any of these three radicals, and when R.sub.4 represents a substituted or unsubstituted phenyl radical, a benzyl radical or a radical ##STR9## then R.sub.5 does not represent any of these three radicals, or R.sub.1 represents a heterocyclic residue selected from 2-, 3- or 4-pyridyl, 2- or 3-thienyl, and 2- or 3-furyl unsubstituted or substituted with a methyl radical,and at least one coupler, said coupler being a halogenated meta-aminophenol of formula II, or an acid addition salt thereof: ##STR10## in which: R.sub.7 and R.sub.8 are identical or different and represent a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 monohydroxyalkyl, C.sub.2 -C.sub.4 polyhydroxyalkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 monohydroxyalkoxy or C.sub.2 -C.sub.4 polyhydroxyalkoxy radical;R.sub.9 and R.sub.10 are identical or different and represent a hydrogen atom, a C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 monohydroxyalkyl, C.sub.2 -C.sub.4 polyhydroxyalkyl or C.sub.1 -C.sub.4 monoaminoalkyl radical; andat least one of the R.sub.7 and R.sub.8 radicals represents a halogen atom.