Patent ID: 8404855
Filing Date: 2013-03-26
Classification: C07D

Abstract:
1. A method for the manufacture of a compound of the formula (I) in which A represents pyrid-3-yl which is optionally substituted in the 6-position by fluorine, chlorine, bromine or trifluoromethyl, or represents 1,3-thiazol-5-yl which is optionally substituted in the 2-position by chlorine; B represents oxygen, sulphur or methylene; R R R which method comprises reacting a compound of the formula (II) in which B represents oxygen, sulphur or methylene; R R with a compound of the formula (III) in which A represents pyrid-3-yl which is optionally substituted in the 6-position by fluorine, chlorine, bromine or trifluoromethyl, or represents 1,3-thiazol-5-yl which is optionally substituted in the 2-position by chlorine; and R in the presence of an acidic auxiliary selected from p-toluenesulfonic acid or acetic acid, optionally in the presence of a suitable diluent.