Patent ID: 9110062
Filing Date: 2015-08-18
Classification: A61K,A61P,C12Q,G01N

Abstract:
1. A method of treating a vascular disease in a patient, the method comprising: administering a treatment regimen comprising administration of an anti-platelet inhibitor to a patient having vascular disease; and administering an adjusted treatment regimen based on the risk of a thrombotic event in the patient, wherein the patient is at risk of a thrombotic event when a test score for the patient is greater than a risk threshold score based on a population study, wherein the test score is determined by assaying in vitro platelet function in a blood sample from the patient, wherein platelet function is assayed by assaying platelet reactivity, time-to-thrombin formation (TTF), or time-to-fibrin formation (TFF) in the blood sample in response to an agonist, and wherein assaying platelet reactivity is by a method other than assaying GP IIb/IIIa receptor expression, said assaying platelet function providing the test score, wherein the test score is independent of a pre-treatment baseline of platelet reactivity in the patient based on said identifying.