Patent ID: 8178101
Filing Date: 2012-05-15
Classification: A61K,C07K

Abstract:
1. A method of treating cachexia by administering an anti-human IL-6 antibody or anti-human IL-6 antibody fragment wherein the method comprises administering to a subject in need thereof an effective amount of an anti-human IL-6 antibody or anti-human IL-6 antibody fragment which specifically competes for binding to the human IL-6 epitope specifically bound by the anti-IL-6 antibody comprising the variable light and heavy chain in SEQ ID NO:2 and 3 respectively, wherein said competition can be detected in a competitive binding assay using said antibody or antibody fragment, the human IL-6 polypeptide in SEQ ID NO:1, and the anti-IL-6 antibody comprising the variable light and heavy chain in SEQ ID NO:2 and 3 respectively.