Patent ID: 8247206
Filing Date: 2012-08-21
Classification: A61P,C07K,C12N

Abstract:
1. A recombinantly produced chimeric fusion protein consisting of: (1) one or two fusion modules, each fusion module consisting of: (2) optionally a target polypeptide located at the N-terminal end, at the C-terminal end, or at the N-terminal and the C-terminal ends of the one or two fusion modules; and (3) optionally a hexa-histidine sequence tag consisting of the amino acid sequence of SEQ ID NO: 24 for facilitating purification and refolding of the recombinantly produced chimeric fusion protein; wherein the one or two fusion modules and the target polypeptide are optionally separated by a linker sequence and wherein the target polypeptide and the hexa-histidine sequence tag are optionally separated by a spacer sequence, and wherein the recombinantly produced chimeric fusion protein has protein folding activity.