Patent ID: 6590043
Filing Date: 2003-07-08
Classification: A61K,C08F,C08G

Abstract:
A block copolymer having a hydrophilic polymer segment and hydrophobic polymer segment which has the following formula (I-câ€²âˆ’1) wherein:R1 is an unsubstituted or substituted straight-chain or branched C1-15 alkoxy group, an unsubstituted or substituted aryloxy group, or an unsubstituted or substituted aryl-C1-3 alkoxy group, and, when R1 is a substituted group, the substituent is vinyl group; an acetal-forming group which is a substituent on the end carbon atom of the C1-5 alkoxy group and is selected from the group consisting of wherein S is an integer in the range of 1 to 6; a cyano group; an aldehyde group; a carboxyl group; an amino group; a C1-6 alkoxycarbonyl group; a C2-7 acylamide group; a tri(C1-6alkyl)siloxy group having the same or different alkyl groups; a siloxy group; or a silylamino group; Z represents the group: â€”CH2(CH2)rNR6R7 wherein R6 and R7 are the same or different and represent C1-6 alkyl groups, and r is 0 or 1; p is an integer which is selected such that a polymer micelle can be formed from the copolymer molecules in an aqueous medium and which is not greater than 1,000; and m is an integer in the range of 5 to 10,000.