Patent ID: 7776909
Filing Date: 2010-08-17
Classification: A61P,C07C,C07D

Abstract:
1. A method of treatment of psoriasis, ulcerative colitis, melanoma, chronic obstructive pulmonary disease (COPD), bullous pemphigoid, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and in the treatment of damages caused by reperfusion after ischemia comprising administering a compound of formula (Ia): or a pharmaceutically acceptable salt thereof, wherein A is selected from benzene, naphthalene, pyridine, pyrimidine, pyrrole, imidazole, furane, thiophene, indole and 7-aza-indole and labels 1 and 2 mark the relevant positions on the A ring; the X atom is selected from N (nitrogen) and C (carbon); R is a substituting group on the A ring selected from: Hy is selected from the group consisting of methyl, ethyl, chlorine, bromine, methoxy and trifluoromethyl Rd is C