Patent ID: 8932578
Filing Date: 2015-01-13
Classification: A23L,A23V,A61K,A61P,C12N,C12Q,C12Y,Y02A

Abstract:
1. A method for lowering of intraluminal bile acid of an animal comprising administering to the animal a bile acid lowering amount of a composition comprising (a) a bile-permeable microcapsule comprising a bacterial cell expressing a bile acid deconjugating enzyme; and (b) a carrier; wherein the bile acid deconjugating enzyme is present in an amount sufficient to deconjugate bile in the microcapsule in the small intestine; and wherein the bile-permeable microcapsule permits entry of bile and retains at least a portion of bile acid precipitate produced from the bile by the bile acid deconjugating enzyme.