Patent ID: 8846760
Filing Date: 2014-09-30
Classification: A61P,C07C

Abstract:
1. A method of treating a disorder associated with the N-Formyl peptide receptor 2 modulation, wherein the disorder is selected from: ocular inflammatory diseases, wet age-related macular degeneration, dry age-related macular degeneration, corneal wound healing, uveitis, dry eye, Keratitis, allergic eye diseases, conditions affecting the posterior part of the eye, maculopathies, retinal degeneration, non-exudative age related macular degeneration, exudative age related macular degeneration, choroidal neovascularization, diabetic retinopathy, retinopathy of prematurity acute macular neuroretinopathy, central serous chorioretinopathy, cystoid macular edema, diabetic macular edema, infectious keratitis, herpetic keratitis, corneal angiogenesis, lymphangiogenesis, post-surgical corneal inflammation, and blepharitis, which comprises administering to a mammal in need thereof, a pharmaceutical composition comprising a therapeutically effective amount of at least one compound represented by Formula I or a pharmaceutically acceptable salt thereof: wherein: “ “ R R R R R R Y is O or S; X is O, NR, or CH R heteroaryl, C 3-8 cycloalkyl, C 3-8 cycloalkenyl or H; R c is 0, 1 or 2; R R R R R R R R R R is H, —C with the provisos when “ the compound is not of structures