Patent ID: 6451836
Filing Date: 2002-09-17
Classification: A61K,A61P,C07D,Y10S

Abstract:
A method of inhibiting liver glycogen phosphorylase comprising administering to a subject in need thereof an effective amount of a compound of formula I whereinR1 is hydrogen, acyl, alkene, cycloalkyl or alkyl which optionally is substituted with one or more of the following groups: hydroxy, alkoxy, amino, N-alkylamino, N,N-dialkylamino, halogen, cycloalkyl optionally substituted phenyl or alkoxycarbonyl, R2 is hydrogen, R3 and R4, which are the same or different, independent of each other, is hydrogen, halogen, hydroxy, mercapto or amino which is optionally substituted with alkyl or aralkyl, and R5 is alkyl substituted with hydroxy, halogen, amino, N-alkylamino, N,N-dialkylamino or mercapto, or a salt or hydrate thereof.