Patent ID: 6340471
Filing Date: 2002-01-22
Classification: A61K,Y10S

Abstract:
A method for preparing a drug delivery system for transporting drug active particles for ingestion by a subject recipient, said delivery system comprising a suspension comprising a lipid source in which said particles and other dry solids are homogeneously suspended, said method comprising the steps of:microencapsulating said drug particles by granulating with a filming agent, melting said lipid source to a liquid state, adding a surfactant to said melted lipid source to enhance coating of said lipid source, mixing said dry solids and said microencapsulated drug particles within said melted liquid lipid source until said suspension is formed such that said dry solids and said microencapsulated drug particles are continuously coated by said lipid source such that said suspension exhibits pseudoplastic and/or thixotropic properties, and molding said suspension into an oral dosage form for swallowing or chewing.