Patent ID: 8906414
Filing Date: 2014-12-09
Classification: A61K

Abstract:
1. A nanoparticle complex having a size equal to or less than 80 nm comprising: a catechin capable of enhancing α-secretase activity; and a lipid carrier wherein the lipid carrier is comprised of a monophasic liquid preparation comprised of a mixture of phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) and phosphatidylinositol (PI); wherein the catechin and the lipid carrier are co-solubilized to form the nanoparticle complex in which the catechin is not encapsulated within the nanoparticle complex; wherein the complex contains about 1 mg of the lipid carrier and between about 8 mg and about 16 mg of the catechin; wherein concentration of the catechin is between about 3 μM and about 6 μM.