Patent ID: 8637076
Filing Date: 2014-01-28
Classification: A61K

Abstract:
1. An orally disintegrating tablet comprising: a) a plurality of rapid release taste masked particles wherein the rapid release taste masked particles comprise: wherein the taste masking coating comprises about 25% to about 55% by weight of the rapid release taste masked particles, wherein at least 90% of the rapid release taste masked particles pass through a 30 mesh screen and not less than 60% of the rapid release taste masked particles are retained on a 60 mesh screen and the rapid release taste masked particles have a total moisture content of less than 5% by weight of the rapid release taste masked particles, b) about 3% to about 25% by weight of the tablet of an effervescent couple; c) about 2% to about 20% by weight of the tablet of a noneffervescent disintegrant selected from the group consisting of microcrystalline cellulose, croscarmellose sodium, crospovidone, alginates, starches such as corn starch, potato starch and modified starches thereof, gums such as agar and guar, and combinations thereof; and d) at least one excipient selected from the group consisting of a filler, a binder, a flavor, a color, a lubricant, a glidant and a pH adjusting agent, and wherein the tablet has a moisture content of 5% or less by weight of the tablet, and disintegrates in a patient's mouth in 60 seconds or less to provide a suspension or slurry of the rapid release taste masked particles which can be swallowed.