Patent ID: 6984307
Filing Date: 2006-01-10
Classification: C12Q,G01N

Abstract:
1. A dry reagent diagnostic device for the simultaneous enzymatic analysis of two different analytes in a single application of a single 1–20 ul sample of whole blood, wherein the fast analyte is determined by a fast reaction zone, and a second reaction zone, physically separated from the first reaction zone, determines the second analyte; a fluid bridge formed by the applied sample connects the two reaction zones; said first reaction zone and second reaction zone having reaction materials and geometry; selected to allow simultaneous rehydration and activation of both zones by a single unseparated whole blood drop; said reaction zone materials and geometry being selected so as to return detectable analyte signals in the presence of whole blood; said reaction zone materials and geometry being selected as to generate a detectable sample application signal upon initial contact with whole blood; said detectable sample application signal being capable of triggering an automated reaction zone reader which is capable of performing subsequent test timing in an automated manner; and at least one of the reaction zones produces a detectable change in an optical signal.