Patent ID: 8598359
Filing Date: 2013-12-03
Classification: A61P,C07D

Abstract:
1. A compound of formula: wherein Ar is selected from the group consisting of X is selected from the group consisting of direct bond, O, NR Ar is attached to X via a ring atom of Ar; R R R Q is —O—; n is an integer selected from 1-5; HET is selected from the group consisting of piperidine and piperazine, wherein said piperidine or piperazine is optionally substituted with one or two substituents independently selected from the group consisting of hydroxyl, carboxy, loweralkyl, benzyl, and benzyloxy; and taken together ZW is H or Z is (CH W is selected from the group consisting of acyl, hydroxyl, carboxyl, C(O)NHR R