Patent ID: 8957043
Filing Date: 2015-02-17
Classification: A61K,A61P,C07K

Abstract:
1. A method of treating retinitis pigmentosa in a subject, the method comprising directly administering to the retinal cells of the subject a pharmaceutical composition comprising: a) a viral vector comprising a nucleic acid, wherein the nucleic acid comprises a nucleotide sequence encoding a Rod-Derived Cone Viability Factor 1 (RDCVF1) or a Rod-Derived Cone Viability Factor 2 (RDCVF2) polypeptide and wherein the nucleotide sequence is operably linked to an expression control sequence, and b) a pharmaceutically acceptable carrier, wherein expression of the RDCVF1 or RDCVF2 polypeptide in the retinal cells of the subject treats the retinitis pigmentosa.