Patent ID: 6228955
Filing Date: 2001-05-08
Classification: C07D,C08F

Abstract:
A process for preparing an enantiomerically enriched chiral epoxide of formula I ##STR6##wherein R.sup.1, R.sup.2 and R.sup.3 are each independently selected from H, R, R--CO-- and R--O--CO--, each R independently being substantially a hydrocarbon group of up to 20 carbon atoms, and X is an alkyl or cycloalkyl group of up to 10 carbon atoms, provided that --CO--X is not enolisable, wherein said process comprises the asymmetric epoxidation of corresponding prochiral alkene of formula IIR.sup.1 R.sup.2 C.dbd.CR.sup.3 --CO--X (II)by reaction with an oxidant in the presence of a chiral catalyst.