Patent ID: 7928246
Filing Date: 2011-04-19
Classification: A61P,C07D

Abstract:
1. A pharmaceutical composition of wherein R R A is aryl; B is heteroaryl said heteroaryl being connected to N(1) through a ring carbon atom adjacent to a ring nitrogen, and additionally said heteroaryl having an additional 0 to 3 heteroatoms selected from 0, S, and N, wherein one or more ring nitrogen atoms in said heteroaryl can be optionally in an N-oxide form, and said heteroaryl being further optionally substituted with 1 or 2 members selected from optionally substituted C X is optionally substituted C Y is O, S, S(O), S(O) or an optical isomer, enantiomer, diastereomer, racemate, or pharmaceutically acceptable salt thereof and at least one pharmaceutically acceptable carrier, further comprising at least one additional agent, drug, medicament, antibody and/or inhibitor for treating, ameliorating or preventing a glucokinase mediated disease.