Patent ID: 7879326
Filing Date: 2011-02-01
Classification: A61K,A61P,C07K

Abstract:
1. An isolated human monoclonal antibody or variable region fragment thereof that specifically binds to H5N1, wherein: the antibody heavy chain variable region comprises a CDR1 amino acid sequence (SEQ ID NO:13) GSSMRTHY; a CDR2 amino acid sequence (SEQ ID NO:14) IYYSGST and a CDR3 sequence (SEQ ID NO:15) ARTKHFDILPGGVFDM; and the antibody light chain variable region comprises a CDR1 amino acid sequence (SEQ ID NO:16) RLGDKY, a CDR2 amino acid sequence (SEQ ID NO:17) QDT, a CDR3 amino acid sequence (SEQ ID NO:18) QAWDSNIGV; or a light chain variable region comprising a CDR1 amino acid sequence (SEQ ID NO:19) KSVSTSGSY, a CDR2 amino acid sequence (SEQ ID NO:20) LVS, and a CDR3 amino acid sequence (SEQ ID NO:21) QHIRELTR.