Patent ID: 7186726
Filing Date: 2007-03-06
Classification: A61K,A61P,C07D

Abstract:
1. A compound of the formula: or the salt or stereoisomeric forms thereof, wherein each R wherein a combination of R n wherein X is selected from the group consisting of: (a) alkyl (1–12C) or alkenyl (2–12C) optionally including one or more N, O or S with the proviso that any N included in a ring is secondary or is tertiary solely because of an alkyl substitution; (b) aryl, provided that if aryl is phenyl or pyridyl, said aryl must contain at least one substituent and wherein if said aryl is phenyl and contains only one substituent, said substituent must comprise an aryl group or a trialkylsilyl group and wherein said phenyl is not 2,3-dimethylphenyl or fused to an aliphatic ring; (c) —CRH-aryl wherein R is H, alkyl, or a heteroaromatic ring, wherein when R is H, aryl is optionally substituted 4-pyridyl, or is substituted phenyl other than phenyl fused to an aliphatic ring, or is substituted naphthyl or is substituted 5-membered aryl; and (d) -alkylene-aryl wherein said alkylene contains at least 2 C, and further optionally contains one heteroatom and/or is substituted by ═O and/or OH provided that if said alkylene is CH