Patent ID: 6777430
Filing Date: 2004-08-17
Classification: A61P,C07D

Abstract:
A compound of formula I, or a pharmaceutically acceptable salt thereof: whereinZ represents an optionally substituted five-membered heteroaromatic ring selected from furan, thiophene, pyrrole, oxazole, thiazole, isoxazole, isothiazole, imidazole, pyrazole, oxadiazole, thiadiazole, triazole and tetrazole; E represents a chemical bond or a straight or branched alkylene chain containing from 1 to 4 carbon atoms, optionally incorporating an oxygen atom to form an ether linkage; M represents the residue of a piperidine ring; R1 represents an optionally substituted aryl(C2-4)alkyl group; and R21 represents hydrogen or halogen.