Patent ID: 8748610
Filing Date: 2014-06-10
Classification: A01N,A61K,A61P,C07F

Abstract:
1. A compound of Formula (I): or any pharmaceutically-acceptable salt or hydrate thereof, wherein: L is Ar is each X is independently N or C; R each R each R 3 is independently (a) —H, CH (b) two R (c) two R or a wherein each R 4 is independently: (a) (C (b) (C (c) —H, CH each R (a) N(R (b) each R 5 is independently: (a) —H, halo, (C (b) (C R 7 is —H, (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl, (C 2 -C 6 )alkynyl, (C 3 -C 8 )cycloalkyl, (C 5 -C 8 )cycloalkenyl, phenyl, (C 1 -C 6 )haloalkyl, (C 1 -C 6 )hydroxyalkyl, (C 1 -C 6 )alkoxy(C 1 -C 6 )alkyl, (C 1 -C 6 )alkyl-N(R 10 ) 2 , or CON(R 10 ) 2 ; and R 10 is —H, (C 1 -C 4 )alkyl, (C 1 -C 4 )haloalkyl, (C 1 -C 4 )hydroxyalkyl, or (C 1 -C 4 )alkoxy(C 1 -C 4 )alkyl.