Patent ID: 6140468
Filing Date: 2000-10-31
Classification: C12N

Abstract:
A recombinant human prostate specific antigen (hPSA) which is obtainable by recombinant DNA technology using a baculovirus expression system in infected insect cells, wherein the first thirteen N-terminal amino acids of said recombinant hPSA consists of Ser-Arg-Ile-Val-Gly-Gly-Trp-Glu-Cys-Glu-Lys-His-Ser (SEQ ID NO:1), does not form complexes with .alpha..sub.1 -antichymotrypsin or .alpha..sub.2 -macroglobulin and has no activity on the substrates MeO-Suc-Arg-Pro-Tyr-pNA.HCl and H-D-Pro-Phe-Arg-pNA.2HCl.