Patent ID: 6316422
Filing Date: 2001-11-13
Classification: A61K,C07J

Abstract:
A compound of general formula I or a salt thereof ##STR7##in which:R1 represents a cholesterol derivative or an alkylamino --NR'R"" group, with R' and R"" independently representing a saturated or unsaturated, linear or branched C.sub.12 to C.sub.22 aliphatic radical;R2 and R3 independently represent hydrogen or a group of general formula II with at least one of R2 and R3 being different from hydrogen, ##STR8##in which:n and m independently represent an integer between 0 and 4 and are distinct between the groups R2 and R3; andR4 and R5 independently represent hydrogen or a group of formula III: ##STR9##in which p and q independently represent an integer from 0 to 4 and r is equal to 0 or 1, with the following conditions: (A) when r is equal to 1, (1) X represents an NH group and x is equal to 1 or (2) X represents nitrogen and x is equal to 2; (B) it is possible for p, q and r to vary independently between the groups R4 and R5; (C) at least one of R4 or R5 is different from hydrogen; and (D), when R1 is a cholesterol derivative, n is 4, m is 1, one of R2 or R3 is hydrogen, and one of R4 or R5 is hydrogen; R4 or R5, whichever is not hydrogen, is not a group of formula III in which p, r, and q are equal to 0 and x is equal to 1.