Patent ID: 6803383
Filing Date: 2004-10-12
Classification: C07C

Abstract:
A compound of structure: wherein G1 and G2 are each independently â€”NHâ€”C(O)â€”Oâ€”R1, â€”NHâ€”C(O)â€”Oâ€”(CH2)&ngr;â€”(C6H4)â€”X1, â€”NHâ€”C(O)â€”NHâ€”(CH2)&ngr;â€”(6H4)â€”X1, â€”Oâ€”C(O)â€”NHâ€”(CH2)&ngr;â€”(C6H4)â€”X1, â€”Oâ€”C(O)â€”Oâ€”(CH2)&ngr;â€”(C6H4)â€”X1, or â€”NHâ€”C(O)â€”CH2â€”(C6H4)â€”X1; Y1 and Y2 are each independently OH, C1-C4 alkyl, C1-C4 hydroxyalkyl, C1-C4 alkoxy, phenyl, benzyl, or â€”NH2; R1 is C1-C4 alkyl; X1 is halo, nitro, C1-C4 alkyl, C1-C4 alkoxy, or C1-C4 perfluoroalkyl; Z is â€”Câ‰¡Câ€”, â€”C6H4â€”, cis â€”CH&boxH;CHâ€”, trans â€”CH&boxH;CHâ€”, cis â€”CH2â€”CH&boxH;CHâ€”CH2â€”, trans â€”CH2â€”CH&boxH;CHâ€”CH2â€”, 1,4-naphthyl, cis-1,3-cyclohexyl, trans-1,3-cyclohexyl, cis-1,4-cyclohexyl, or trans-1,4-cyclohexyl; A is H or a covalent bond; m and n are each independently an integer having a value of 0 or 1; t is an integer having a value of 0 or 1; and &ngr; is an integer having a value of 1 or 2; with provisos that when A is H, t is 0; when A is a covalent bond, t is 1; when m is 0, Y1 is C1-C4 hydroxyalkyl; and when n is 0, Y2 is C1-C4 hydroxyalkyl.