Patent ID: 7867977
Filing Date: 2011-01-11
Classification: A61K,A61P,C07K

Abstract:
1. An isolated immunogenic peptide comprising the amino acid sequence SPQNSIRHNL (SEQ ID NO: 3), a functional portion or functional variant thereof, or a pharmaceutically acceptable salt thereof, wherein the peptide, or functional portion or functional variant thereof, binds to an MHC Class I molecule, provided that the peptide does not consist of the amino acid sequence TIGNGLSPQNSIRHNLSL (SEQ ID NO: 4) or NPTGTIGNGLSPQNSIRHNLSLH (SEQ ID NO: 5), wherein the functional portion comprises 50% or more of the immunogenic peptide comprising SEQ ID NO: 3, wherein the functional variant comprises one conservative amino acid substitution, and wherein the peptide consists of 8 to 10 amino acids.