Patent ID: 8524717
Filing Date: 2013-09-03
Classification: A61P,C07C,C07D

Abstract:
1. A compound of Formula I or a pharmaceutically acceptable salt thereof: wherein each of R1-R5 is optionally substituted and independently chosen from —H, halo, alkyl, alkoxy, cycloalkoxy, haloalkyl, haloalkoxy, -L-aryl, -L-heteroaryl, -L-heterocyclyl, -L-carbocycle, acylamino, acyloxy, alkylthio, cycloalkylthio, alkynyl, amino, aryl, arylalkyl, arylalkenyl, arylalkynyl, arylalkoxy, aryloxy, arylthio, heteroarylthio, cyano, cyanato, haloaryl, hydroxyl, heteroaryloxy, heteroarylalkoxy, isocyanato, isothiocyanato, nitro, sulfinyl, sulfonyl, sulfonamide, thiocarbonyl, thiocyanato, trihalomethanesulfonamido, O-carbamyl, N-carbamyl, O-thiocarbamyl, N-thiocarbamyl, and C-amido; R6 is chosen from —H and alkyl; R7 is chosen from —H, alkyl, and cycloalkyl; R8 is chosen from —C(═O)NR R R R each L can be saturated, partially saturated, or unsaturated, and is independently chosen from —(CH