Patent ID: 6365607
Filing Date: 2002-04-02
Classification: A61K,A61P

Abstract:
A method for treating progressive loss of body weight in a diabetic mammal, which comprises administering to said mammal an effective amount of a compound of the formula: wherein R represents a hydrocarbon group that may be substituted or a heterocyclic group that may be substituted; Y represents a group of the formula â€”COâ€”, â€”CH(OH)â€”, or â€”NR3â€” wherein R3 represents an alkyl group that may be substituted; m is 0 or 1; n is 0, 1 or 2; X represents CH or N; A represents a bond or a bivalent aliphatic hydrocarbon group having 1 to 7 carbon atoms; Q represents oxygen or sulfur; R1 represents hydrogen or an alkyl group; ring E may have further 1 to 4 substituents, which may form a ring in combination with R1; L and M respectively represent hydrogen or may be combined with each other to form a bond; provided that R does not represent dihydrobenzopyranyl when m and n are 0, X represents CH, A represents a bond, Q represents sulfur, R1, L and M respectively represent hydrogen, and ring E does not have further substituents; or a salt thereof.