Patent ID: 7119207
Filing Date: 2006-10-10
Classification: A61P,C07D

Abstract:
1. A compound of the formula wherein Q is C═NH, C═CH B is hydrogen, methylene, or ethylene; when B is hydrogen, A is CH when B is methylene or ethylene, A is CH, CH(C Y is N and Z is CH, or Y is CH and Z is N; G is NH(CH with the proviso that when q is zero, G is —NH—, —S— or —O—; W is a one carbon linking group (i.e., methylene) or a saturated or unsaturated two or three carbon linking group, wherein each of the foregoing W groups can optionally be substituted with one substituent R or W is a saturated two carbon chain linking group that forms, together with a separate 1, 2 or 3 carbon chain, a fused 3, 4 or 5 membered ring, respectively; or W is a saturated two carbon chain linking group, wherein one of the two carbons in the chain forms, together with a separate 2, 3, 4 or 5 carbon chain, a 3, 4, 5 or 6 membered spiro ring, respectively; p is one; R and wherein the heterocyclic ring substituents on the alkyl groups of R and wherein the heterocyclic ring substituents on the alkyl groups of R and wherein the phenyl groups of R each of R or R or R with the proviso that no more than one of R R R R each R or R and wherein the phenyl groups in the definition of R or a pharmaceutically acceptable salt thereof.