Patent ID: 6040336
Filing Date: 2000-03-21
Classification: A61K,A61P,Y10S

Abstract:
A method for treating bacterially induced meningitis, comprising administering an effective amount of a compound of formula I or Ia ##STR3## wherein X.sup.1 is a --CH.sub.2 --CH.sub.2 --, trans --CH.dbd.CH-- or --C.tbd.C-- group,X.sup.2 is a linear or branched saturated hydrocarbon chain having from 1 to 6 carbon atoms,X.sup.3 is an --O-- or --CH.sub.2 -- group,X.sup.4 is a --CH.sub.2 -- or (--CH.sub.2).sub.3 -- group,X.sup.5 is a hydrogen atom or a --C.tbd.C--R.sup.2 group,R.sup.1 is a hydrogen atom, an alkyl group having from 1 to 6 carbon atoms, a cycloalkyl group having 5 or 6 carbon atoms or a phenyl group,R.sup.2 is a linear or branched, saturated or unsaturated hydrocarbon chain having from 1 to 6 carbon atoms,R.sup.3 is a hydrogen atom, an acyl radical having from 1 to 4 carbon atoms or a benzyl radical, andR.sup.4 is a hydrogen atom or a methyl group,wherein the O--R.sup.3 -- group is in the .alpha.- or .beta.-configuration,or a salt thereof with a physiologically tolerable base when R.sup.1 represents a hydrogen atom.