Patent ID: 8467974
Filing Date: 2013-06-18
Classification: B01J,G01N,G16B,Y10S

Abstract:
1. A method of determining at least one genotype call for at least two nucleic acid samples, the method comprising: inputting at least two sets of hybridization intensity data into a computer, wherein the computer comprises a computer program designed to receive sets of hybridization intensity values, and wherein the sets of hybridization intensity values are based upon emission intensity data obtained by hybridizing a nucleic acid sample with a nucleic acid probe array; assigning, with the computer program, quantitative representations to at least a portion of each set of hybridization intensity values, wherein the quantitative representations are each based upon one or more hybridization intensity values; calling, with the computer program, at least one genotype call for each nucleic acid sample, wherein the at least one genotype call is based upon the quantitative representations; calculating, with the computer program, a quantitative difference between the quantitative representations of at least two nucleic acid samples; and determining, with the computer program, whether the at least one genotype call is different between the at least two nucleic acid samples, wherein determining comprises analysis of the quantitative difference between the quantitative representations upon which the at least one genotype call was based.