Patent ID: 7524859
Filing Date: 2009-04-28
Classification: A61K,A61P,C07D

Abstract:
1. A method of treatment of a hyperproliferative disorder selected from breast cancer, head cancer, neck cancer, gastrointestinal cancer, leukemia, ovarian cancer, bronchial cancer, lung cancer, pancreatic cancer, sinonasal natural killer/T-cell lymphoma, testicular cancer (seminoma), thyroid carcinoma, malignant melanoma, adenoid cystic carcinoma, angiosarcoma, anaplastic large cell lymphoma, endometrial carcinoma, or prostate carcinoma, comprising administering an effective amount of a compound of Formula III: wherein: R12 is aryl, C R22 is hydrogen; C R32 is hydrogen; halogen; hydroxy; acyloxy; substituted acyloxy; C A E or E G1 is C J1 is O or wherein R 62 is hydrogen or N-protective group; X Y provided that Y