Patent ID: 7744851
Filing Date: 2010-06-29
Classification: A61K

Abstract:
1. A method for preparing an anhydrous 18 F-radiolabeled fluorinating agent having the formula [Q n M] x+ ( 18 F − ) x , wherein: Q is an organic moiety selected from the group consisting of alkyls, heteroalkyls, aryls, heteroaryls, alkenyls, alkynyls, and polymers; n is an integer such that [Q M is a moiety capable of supporting a positive charge; and x is an integer representing the number of formal positives charge(s), +, carried by the [Q the method comprising: (a) a nucleophilic reaction of a an aromatic compound, an electron deficient aromatic compound, a heteroaromatic compound, and an electron deficient heteroaromatic compound; to produce a 18 F-radiolabeled carrier compound; and (b) reacting the