Patent ID: 6479491
Filing Date: 2002-11-12
Classification: A61P,C07D

Abstract:
A compound of formula (I) any of its enantiomers or any mixture thereof, or a pharmaceutically acceptable acid addition salt thereof, wherein:R1, R2, R3, R4, R11, R12, R13, R14, and R15 each independently are hydrogen, alkyl, alkoxy, halogen, trifluoromethyl, nitro, cyano, amino, aminoalkyl, aminodialkyl, acyl, aminocarbonyl, or acylamino, provided that R11, R12, R13, R14, and R15 are not all hydrogen at the same time; R5 is hydrogen, alkyl, alkoxyalkyl, or phenylalkyl; X is â€”CH2â€”Zâ€”, â€”Zâ€”CH2â€”, â€”NHâ€”COâ€”, â€”COâ€”NHâ€” or â€”CH&boxH;CHâ€”, wherein Z is O, S, CH2, or NH; Y is O; and n is 0, 1 or 2.