Patent ID: 7662911
Filing Date: 2010-02-16
Classification: A61K,B01J

Abstract:
1. A method of making a film, the method comprising: depositing a first layer polyelectrolyte on a surface of a substrate to form a first layer; and depositing a second layer polyelectrolyte on the first layer polyelectrolyte to form a second layer; wherein a bioactive molecule is co-deposited with the first layer polyelectrolyte, second layer polyelectrolyte, or both, or wherein the substrate comprises a bioactive molecule; wherein the first layer polyelectrolyte, the second layer polyelectrolyte, or both, is deposited using a solution comprising a polymeric precipitant at a concentration to improve retention of the bioactive molecule; wherein the polymeric precipitant, the first layer polyelectrolyte and the second layer polyelectrolyte are different; and wherein the first layer polyelectrolyte and the second layer polyelectrolyte have net charges of opposite polarity.