Patent ID: 7495024
Filing Date: 2009-02-24
Classification: A61K,A61P,C07D

Abstract:
1. A method for preventing or treating atherosclerotic plaque in human patients comprising administering to a patient a composition containing a compound of the formula: wherein R is hydrogen, lower alkyl, halogen, trifluoromethyl, lower alkoxy or hydroxy; Y is —O— or —S—; L is lower alkylene or lower alkenylene; X is a branched- or straight-chain lower alkylene and M is selected from the group consisting of hydrogen, a pharmaceutically acceptable cation and a pharmaceutically acceptable metabolically cleavable group selected from —COR, —COOR, —CONRR and —CH or pharmaceutically effective salts thereof with said compound being administered in an amount effective to prevent or treat atherosclerotic plaque consisting of a daily dosage of from about 0.2 to about 3.0 mg/kg of body weight.