Patent ID: 6441237
Filing Date: 2002-08-27
Classification: C07C,C07D

Abstract:
A compound of general formula 1 wherein:R1 and R2 independently of one another are hydogen, C1-C4-alkyl, benzyl, furylmethyl, cycloalkyl, cycloalkyl-methyl, C2-C4-alkenyl, C2-C4-alkynyl, C1-C4-alkoxy-(CH2)1â€”, or C3-C6-cycloalkoxy-(CH2)mâ€”, wherein 1 is an integer 1, 2, or 3, and m is an integer 1, 2, or 3, or R1 and R2 together with the nitrogen atom form a 5- or 6- membered heterocyclic ring which is optionally substituted with 1, 2, or 3 methyl groups or a dimethylene group; n is an integer 0, 1, 2, or 3; R3 is fluorine, chlorine, or methyl; R4 is hydrogen, fluorine, chlorine, or methyl; R3â€² and R4â€² is hydrogen; R5 and R6 independently of one another is hydrogen or methyl; and R7 and R8 independently of one another is methyl, ethyl, or methoxy, or an optical isomer or corresponding acid addition salt with pharmacologically acceptable acids.