Patent ID: 6410792
Filing Date: 2002-06-25
Classification: A61K

Abstract:
A compound having the formula: or pharmaceutically acceptable salts thereof wherein R1-R5 are each individually selected from the group of substituents including hydrogen, halogen, hydroxyl, thiol lower alkyl, substituted lower alkyl, alkenyl, alkynyl, alkylalkenyl, alkyl alkynyl, alkoxy, alkylthio, acyl, aryloxy, amino, amido, carboxyl, aryl, substituted aryl, heterocycle, heteroaryl, substituted heterocycle, heteroalkyl, cycloalkyl, substituted cycloalkyl, alkylcycloalkyl, alkylcycloheteroalkyl, nitro, and cyano and wherein the compound is not a compound selected from the group consisting of N-(2,6-Dibromo-4-ethyl-phenyl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, N-(2-Amino-phenyl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, N-(2,4-Difluoro-benzyl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, 5-Chloro-2-{2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetylamino}-benzoic acid methyl ester, 5-Amino-2-{2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetylamino}-benzamide, N-(2-Amino-4-benzenesulfonyl-phenyl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, N-(4-Diethylamino-phenyl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, 2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-N-(4-phenylamino-phenyl)-acetamide, N-(3-Dimethylamino-phenyl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, N-(2-Amino-4-propylsulfanyl-phenyl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, N-(7-Hydroxy-naphthalen-1-yl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, N-(4-Chloro-3-nitro-phenyl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, N-(4-Bromo-3-chloro-phenyl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, N-(7-Butoxy-naphthalen-2-yl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, N-(1H-Indazol-6-yl)-2-[4-(2-oxo-2,3-dihydro-benzoidazol-1-yl)-piperidin-1-yl]-acetamide, N-(4-Hydroxy-phenyl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, N-(4-Ethoxy-naphthalen-1-yl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, N-(4Ethoxy-phenyl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, N-(2-Chloro-phenyl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, 2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1yl]-N-(4-phenylazo-phenyl)-acetamide 4-{2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetylamino}-benzamide, N-(4-Acetylamino-phenyl)-2-[4-(2-oxo-2.3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, 2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-N-(4-phenoxy-phenyl)-acetamide, N-(4-Dimethylamino-phenyl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl]-piperidin-1-yl-acetamide, N-(4-Acetyl-phenyl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, N-(4-Nitro-phenyl)-2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, 2-[4-(2-Oxo-2,3dihydro-benzoidazol-1-yl)-piperidin-1-yl]-N-(4-trifluoromethyl-phenyl)-acetamide, N-(3-Chloro-4-nitro-phenyl)-2-[4-(2-oxo-2,3-dihydro-benzoidazol-1-yl)-piperidin-1-yl]-acetamide, N-(4-Chloro-phenyl)-2-[4-(2-oxo-2,3dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetamide, 2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-N-p-tolyl-acetamide, 4-{2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-acetylamino}-benzoic acid methy, ester, N-(4-Methoxy-phenyl)-2-[4-(2-oxo-2,3-dihydro-benzoidazol-1-yl)-piperidin-1-yl]-acetamide, and N-(4-Cyclohexyl-phenyl)-2-morpholin-4-yl-acetamide.