Patent ID: 6662030
Filing Date: 2003-12-09
Classification: A61B,G01N

Abstract:
A method of determining at least one parameter of a region of tissue of a body having a temperature, said method comprising the steps of:(a) modulating said temperature of said region of tissue of said body part between at least two values of temperature, whereby temperature of said region of tissue of said body part is controlled; (b) introducing light at at least one wavelength into said region of tissue of said body part at a surface of said body part and measuring light that is reflected, scattered, absorbed, or emitted by said region of tissue of said body part from an average sampling depth that is confined within said temperature controlled region of tissue of said body part, said average sampling depth not exceeding about 2 mm; (c) measuring at least one optical property of said region of tissue of said body part, at at least on wavelength, as a function of temperature, to obtain an optical, measurement; and (d) analyzing the optical measurement of (c) to obtain a determination of said at least one parameter of said region of tissue of said body part, wherein said at least one parameter is the presence or concentration of glucose in said region of tissue of said body part.