Patent ID: 8093288
Filing Date: 2012-01-10
Classification: A61K,A61P,C07D

Abstract:
1. A method of treating a disorder selected from deficient first-phase insulin secretion, non-insulin dependent diabetes mellitus, or a combination of deficient first-phase insulin secretion and non-insulin dependent diabetes mellitus in a mammal, comprising: i) administering to the mammal a compound represented by the following structural formula: or pharmaceutically acceptable salts thereof, wherein: — — — — is a single or double bond; X X R′ is H or a C1-C5 alkyl; R R R is H or a C1-C5 alkyl; R R R R R R R ii) administering to the mammal a compound represented a structural formula selected from: or pharmaceutically acceptable salts thereof, wherein: ring A is optionally substituted with one or more of —OH, a halo, nitro, cyano, or carboxy; X R is H or a C1-C5 alkyl; R R R