Patent ID: 6495161
Filing Date: 2002-12-17
Classification: A61K,A61P

Abstract:
A macrocapsule containing biologically active materials therein, wherein:said macrocapsule comprises a core and an outer layer, wherein: the core comprises a first biocompatible gellable material which is ionically crosslinkable and which optionally contains at least one microcapsule therein, wherein, when at least one microcapsule is present, each microcapsule comprises a second biocompatible gellable material containing the biologically active materials therein, wherein: at least the outer layer of said macrocapsule is covalently crosslinked or polyionically crosslinked or both polyionically crosslinked and covalently crosslinked, but not ionically crosslinked, and wherein: when microcapsules are not present, at least the outer layer of said first biocompatible gellable material is covalently crosslinked and optionally polyionically crosslinked, but not ionically crosslinked.