Patent ID: 8309722
Filing Date: 2012-11-13
Classification: A61P,C07D

Abstract:
1. A method for preparing a compound of Formula 2F wherein: (i) k is 1; (ii) m is 1; (iii) n is 1; (iv) B is a selected from the group consisting of C (v) R (vi) R (vii) —X—Y— is (R′)N—CH in free base or acid addition salt form, which method comprises the step of reacting a compound of Formula 2E: wherein: (i) k is 1; (ii) m is 1; (iii) n is 1; (iv) A is Cl, Br, F or I; (v) B is selected from the group consisting of C (vi) R (vii) R (viii) X—Y— is a H(R′)N—CH in free base or acid addition salt form, with (a) a copper catalyst; and (b) a base.