Patent ID: 8969568
Filing Date: 2015-03-03
Classification: A61P,C07D

Abstract:
1. A compound of formula 1 wherein R wherein R wherein R wherein R wherein n is either 0 or 1, wherein wherein A, B, D and E are each independently from one another selected from CH wherein ring X is attached to the molecule either via position A, B, D or E, wherein said ring X may optionally be further substituted by one, two or three residues each selected individually from the group consisting of -oxo, hydroxy, —C R R wherein—in case that R wherein R whereby—in case that R whereby—in case that R wherein each of R and wherein each Q is individually selected either from a 5- to 10-membered saturated or partially unsaturated heterocycle comprising 1, 2 or 3 heteroatoms each individually selected from among N, O or S or from a 5- to 10-membered heteroaryl comprising 1, 2 or 3 heteroatoms each individually selected from among N, O and S; whereby Q is attached to the rest of the molecule either via a carbon atom or via an nitrogen atom, the N-oxides of the aforementioned compounds, particularly the 1-naphthyridinyl-oxides of the aforementioned compounds, and the pharmaceutically acceptable salts of the aforementioned compounds.