Patent ID: 8586748
Filing Date: 2013-11-19
Classification: A61P,C07D

Abstract:
1. A compound formula (I): wherein: Ar is phenyl, naphthyl or heteroaryl selected from indolyl, pyridyl, thienyl, pyrazolyl, oxazolyl, indazolyl, benzimidazolyl, isoquinolinyl, 1H-pyrrolo[2,3-b]pyridinyl, benzothienyl, benzofuranyl, 2,1,3-benzothiadiazolyl and 6H-imidazo[2,1-b]thiazolyl, wherein said phenyl naphthyl or heteroaryl is optionally substituted with one to four groups selected from C if Ar is phenyl, two adjacent groups together with the phenyl they are bonded to may form a 2,3-dihydrobenzofuranyl, 1,3-dihydroindol-2-one, or 2-acetyl-3,4-dihydro-1H-isoquinolinyl group; Het is a heteroaryl group selected from: and is optionally substituted with one to two groups independently selected from —CN, —NO R R R or a pharmaceutically acceptable salt thereof.