Patent ID: 6476187
Filing Date: 2002-11-05
Classification: A61K,A61P,C07K,C12Q,G01N

Abstract:
A compound having the general formula:A-B-C-D-E-F-G-amide wherein A is Leu, Ile, or Met;B is Asp or Glu; C is His; D is D-Phe, D-Tyr or D-Nal; E is Arg, Lys, homoArg or homoLys; F is Trp; G is Lys or homoLys; wherein the peptide is cyclized by the formation of an amide bond between the side chain carboxyl group of the Asp or Glu residue at position B in the peptide, and the side chain amino group of the Lys or homoLys residue at position G, and wherein the compound is an agonist of MC-3 melanocortin receptor.