Patent ID: 7465559
Filing Date: 2008-12-16
Classification: C12Q

Abstract:
1. A method for calibrating antimicrobic susceptibility testing data of microorganisms, wherein the method comprises the steps of creating a histogram based on in vitro susceptibility test data against an antimicrobial agent for isolates from a microbial species, which microbial species isolates may contain unknown resistant strains against said antimicrobial agent wherein the number of isolates of microbial species or percentage of the total number of isolates of microbial species is on a y-axis of said histogram and registered response values against said antimicrobial agent on a x-axis of said histogram; determining a position of a response peak of the histogram between a high response side and a low response side corresponding to isolates of microbial species susceptible to said antimicrobial agent; calculating from said high response side of said histogram at least one statistical parameter; and defining a limit for susceptibility interpretation and comparative analysis of antimicrobic resistance, which is based on said at least one statistical parameter; said limit separating susceptible strains from resistant strains against said antimicrobial agent.