Patent ID: 6808900
Filing Date: 2004-10-26
Classification: A61K,A61P,C07K,Y02A,Y10S

Abstract:
An isolated nucleic acid molecule comprising a coding sequence for an immunogenic C. parvum polypeptide, wherein the polypeptide is selected from the group consisting of (a) a polypeptide comprising the sequence of amino acids depicted at amino acid positions 1-193 of FIG. 2A (SEQ ID NO:4), or an immunogenic fragment thereof comprising at least 15 amino acids and that elicits an equivalent or enhanced immunological response as compared to the polypeptide comprising the sequence of amino acids depicted at amino acid positions 1-193 of FIG. 2A wherein the immunological response comprises the ability to elicit the production of neutralizing antibodies against C. parvum, and (b) a polypeptide with at least 90% sequence identity to a polypeptide comprising the sequence of amino acids depicted at amino acid positions 1-193 of FIG. 2A (SEQ ID NO:4) and that elicits an equivalent or enhanced immunological response as compared thereto, wherein the immunological response comprises the ability to elicit the production of neutralizing antibodies against C. parvum.