Patent ID: 7211389
Filing Date: 2007-05-01
Classification: C07K,C12N

Abstract:
1. A method of producing a transgenic plant expressing an immunoglobulin comprising a protection protein in association with an immunoglobulin heavy chain having at least a portion of an antigen binding domain, wherein the protection protein comprises a portion of SEQ ID NO: 2, 4, 6, 8, or 10, comprising: a) introducing into a first plant an expression vector containing a nucleotide sequence encoding the protection protein operably linked to a transcriptional promoter, b) introducing into a second plant an expression vector containing a nucleotide sequence encoding the immunoglobulin heavy chain having at least a portion of an antigen binding domain operably linked to a transcriptional promoter, c) crossing said first plant and said second plant to produce offspring, and d) selecting from said offspring a transgenic plant expressing the immunoglobulin comprising the protection protein in association with the immunoglobulin heavy chain having at least a portion of an antigen binding domain.