Patent ID: 6407277
Filing Date: 2002-06-18
Classification: C07F

Abstract:
A process for the preparation of a phosphoric monoester by reacting an organic hydroxyl compound with a pre-mixed phosphorylating agent consisting essentially of phosphorus pentaoxide and at least one compound selected from the group consisting of water, phosphoric acid and polyphosphoric acid, under such conditions that a) the ratio as defined by formula (I) has a value in the range of from 0.5 to 1.0, and b) the ratio as defined by formula (II) has a value in the range of from 2.8 to 3.2: [Molar&it;â€ƒ&it;amount&it;â€ƒ&it;of&it;â€ƒ&it;phosphorylatingagent&it;â€ƒ&it;represented&it;â€ƒ&it;as&it;â€ƒ&it;P2&it;O5][Molar&it;â€ƒ&it;amount&it;â€ƒ&it;of&it;â€ƒ&it;water&it;â€ƒ&it;includedin&it;â€ƒ&it;the&it;â€ƒ&it;phosphorylating&it;â€ƒ&it;agentrepresented&it;â€ƒ&it;as&it;â€ƒ&it;P2&it;O5&CenterDot;n&af;(H2&it;O)]&it;â€ƒ&it;and(I)[Molar&it;â€ƒ&it;amount&it;â€ƒ&it;of&it;â€ƒ&it;waterincluded&it;â€ƒ&it;in&it;â€ƒ&it;thephosphorylating&it;â€ƒ&it;agentrepresented&it;â€ƒ&it;â€ƒ&it;as&it;â€ƒ&it;P2&it;O5&CenterDot;n&af;(H2&it;O)]+[Molar&it;â€ƒ&it;amount&it;â€ƒof&it;â€ƒ&it;organichydroxylcompound][Molar&it;â€ƒ&it;amount&it;â€ƒ&it;of&it;â€ƒ&it;phosphorylatingagent&it;â€ƒ&it;represented&it;â€ƒ&it;as&it;â€ƒ&it;P2&it;O5]&it;â€ƒ.&it;â€ƒ(II)