Patent ID: 8137327
Filing Date: 2012-03-20
Classification: A61F,A61K

Abstract:
1. A device for insertion into the vagina to deliver a flowable therapeutic formulation to the vaginal surfaces, said device comprising: a reservoir having at least one substantially planar surface; a flowable therapeutic formulation contained throughout the device; wherein said entire device is substantially phobic relative to the flowable therapeutic formulation; a gradation of capillary forces between the reservoir and external surfaces of the device to cause a desorption of the flowable therapeutic formulation from the device when placed in the vagina, the gradation of capillary forces formed by one of: (1) the reservoir and the external surfaces of the device having the same effective capillary radii, a liquid contact angle of less than 60 degrees for the external surfaces of the device, and greater than 60 degrees for the reservoir; (2) the reservoir having a larger pore size than the external surfaces of the device, and the liquid contact angle of the reservoir and the external surfaces of the device are less than 90 degrees; (3) the external surfaces of the device having a larger pore size than the reservoir, and a liquid contact angle of the reservoir and the external surfaces of the device are greater than 90 degrees; and (4) the reservoir and the external surfaces of the device having the same effective capillary radii, and the liquid contact angle is greater than 110 degrees for the external surfaces and greater than 140 degrees for the reservoir.