Patent ID: 6921763
Filing Date: 2005-07-26
Classification: A61P,C07D,C07F

Abstract:
1. A compound of Formula (I): racemic-diastereomeric mixtures, optical isomers, pharmaceutically-acceptable salts or prodrugs thereof wherein: G is where Z  or a group optionally substituted with R  thiazolyl, benzofuranyl, 2,3-dihydrobenzofuranyl, indolyl, isoxazolyl, tetrahydropyranyl, tetrahydrofuranyl, piperidinyl, pyrazolyl, pyrrolyl, pyrrolopyridinyl, H-pyridinone, oxazolyl, isothiazolyl, oxadiazolyl, thiadiazolyl, indolinyl, indazolyl, imidazo[1,2-a]pyridinyl, benzoisothiazolyl, 1,1-dioxybenzoisothiazolyl, pyrido-oxazolyl, pyrido-thiazolyl, pyrimido-oxazolyl, pyrimido-thiazolyl and benzimidazolyl; Z Z R where R Z Z R t for each occurrence is independently an integer from 2 to 6; W for each occurrence is independently a direct bond or O, S, S(O), S(O) R R A is —(C where R for each occurrence is independently H, substituted or unsubstituted alkyl, substituted or unsubstituted arylalkyl or substituted or unsubstituted aryl; R p is 1 or 2; or in a phosphorus containing group, the nitrogen atom, the phosphorus atom, R and R A is NRSO Z R Z Z R a is 1 and D a is 0, and one of D b is 1 and D b is 0, and one of D n for each occurrence is independently an integer from 0 to 6; provided that when A is —N(R)—, Z provided that when Z provided that when Z provided that when Z provided that when R