Patent ID: 8383575
Filing Date: 2013-02-26
Classification: A61K,B82Y,C07K,C12N,G01N

Abstract:
1. A complex comprising a Bacillus amyloliquefaciens barnase bound with high affinity to a Bacillus amyloliquefaciens barstar, and further comprising a cobalamin compound which is bound to an N-terminal end or a C-terminal end of said Bacillus amyloliquefaciens barnase or said Bacillus amyloliquefaciens barstar, wherein said (a) a polypeptide which comprises the amino acid sequence set forth in SEQ ID NO: 11; or (b) a polypeptide which comprises at least 98% sequence identity to the amino acid sequence set forth in SEQ ID NO: 11; and said (a) a polypeptide which comprises the amino acid sequence set forth in SEQ ID NO: 12; or (b) a polypeptide which comprises at least 98% sequence identity to the amino acid sequence set forth in SEQ ID NO: 12.