Patent ID: 8198022
Filing Date: 2012-06-12
Classification: C12Q

Abstract:
1. A method for identifying an increase risk for venous thrombosis, pulmonary embolism, or a combination thereof in a human subject, comprising the steps of: (a) removing a biological sample from the human subject that comprises a nucleic acid sequence that encodes EDG5 protein; (b) screening genomic DNA of said human subject for single polynucleotide polymorphism (SNP) by polymerase chain reaction amplification (PCR) of DNA encoding position 286 of SEQ ID NO:3 of EDG5 protein; and (c) detecting the presence of a nucleotide sequence that encodes for an alanine at position 286 of SEQ ID NO. 3 and determining the presence of the nucleotide sequence is correlated with an increased risk for venous thrombosis, pulmonary embolism, or a combination thereof in said human subject.