Patent ID: 7544374
Filing Date: 2009-06-09
Classification: A61K,A61P,C07K

Abstract:
1. A water-insoluble lipidated glycosaminoglycan particle in the form of a sphere with the glycosaminoglycan portion of the particle forming a shell on the outside and the lipid portion of the particle forming the inside, without the presence of liposome, said particle comprising the reaction product of at least one glycosaminoglycan having a molecular weight within the range of about 1×10 5 to about 1×10 7 daltons, with a lipid consisting of a phosphatidylethanolamine, wherein the ratio of said phosphatidylethanolamine to said at least one glycosaminoglycan is in the range of 1:1 to 20:1 w/w, said particle in the form of a sphere being capable of stably encapsulating drugs or other active ingredients that are soluble in water.