Patent ID: 8759346
Filing Date: 2014-06-24
Classification: A61K,A61P,C07D

Abstract:
1. A method for treating a disease selected from the group consisting of: cognitive disorders, learning and memory deficits and dysfunctions, Alzheimer's disease, prodromal Alzheimer's disease, mild cognitive impairment in the elderly, amnestic mild cognitive impairment in the elderly, age associated memory impairment, Parkinson's disease, the cognitive deficits in schizophrenia, AIDS-dementia, senile dementia, mild cognitive dysfunctions related to age, pseudodementia, Huntington's disease, psychosis, mania, manic depression, schizophrenia, Gilles de la Tourette's syndrome, obsessive compulsive disorders, panic disorders, narcolepsy, nociception, autism, dyslexia, tardive dyskinesia, and chronic fatigue syndrome, in a subject in need thereof, the method comprising: administering to such subject, in free base or pharmaceutically acceptable acid addition salt form, a therapeutically effective amount of a compound of formula (I): wherein n represents 0, 1, 2, 3, 4 or 5, R represents independent from each other hydroxyl, cyano, nitro, halogen, alkyl, alkoxy alkylcarbonyl, alkoxycarbonyl, alkylamine, dialkylamine, alkylcarbonylamine, or alkylcarbamate, and Y represents one of the following groups: