Patent ID: 8765030
Filing Date: 2014-07-01
Classification: A23P,A61K,A61Q

Abstract:
1. A method of microencapsulating an active ingredient with an enteric matrix, the method comprising: a) agitating a combination of water, an enteric matrix material, and an emulsifier at a pH above a solubility of the enteric matrix material to maintain complete dissolution of the enteric matrix material, the combination substantially free of organic solvents, wherein the enteric matrix material is selected from the group consisting of non-deamidated zein, shellac, and mixtures thereof; b) adding a hydrophobic liquid to the combination; c) homogenizing the hydrophobic liquid and the combination to create an emulsion; and d) acid titrating the emulsion under agitated conditions in an amount effective to form a particulate precipitate having enteric functionality, wherein the acid is a food grade acid, and wherein the emulsion is free of oppositely charged particles.