Patent ID: 8932622
Filing Date: 2015-01-13
Classification: A61L,A61P

Abstract:
1. A kit suitable for forming a tissue coating that is capable of preventing undesired tissue-to-tissue adhesions comprising: a) at least one carboxymethyldextran that has been derivatized to provide at least one aminocarboxymethyldextran that contains primary amine groups wherein each said primary amine group is directly bound to a primary, secondary or tertiary carbon atom, said at least one carboxymethyldextran having a weight-average molecular weight of about 1,000 to about 1,000,000 Daltons, and a degree of carboxymethylation of about 0.1 to about 2.5, said at least one aminocarboxymethyldextran having a primary amine substitution level of about 10% to about 150%; and b) at least one carboxymethylcellulose that has been oxidized to provide at least one oxidized carboxymethylcellulose containing aldehyde groups, said at least one oxidized carboxymethylcellulose having a weight-average molecular weight of about 5,000 to about 100,000 Daltons, and an equivalent weight per aldehyde group of about 125 to about 750 Daltons.