Patent ID: 6770778
Filing Date: 2004-08-03
Classification: A61P,C07C

Abstract:
A compound of Formula wherein W is R2 is hydrogen, methyl, fluorine, or chlorine; R3 is hydrogen or fluorine; R4 is â€”CH2S(CH2)m(CH3), â€”Câ‰¡C(CH2)qNHCH3, â€”Câ‰¡Câ€”CH2OCH3, (Z)â€”CHCHCH2OCH3, â€”(CH2)nCO2R6, â€”(CF2)pCF3, â€”CH2(CF2)qCF3, â€”(CH2)mCF(CF3)2, â€”CH(CF3)2, â€”CF2CF(CF3)2, â€”C(CF3)3, â€”Câ‰¡C(CH2)qN(CH3)2, (Z)â€”CHCHâ€”(CH2)qNHCH3, or (Z)â€”CHCHâ€”(CH2)qN(CH3)2, C(O)C1-3 alkyl, or C(O)NHCH3; m is 0 to 1; n is 0 to 2; p is 1 to 5; q is 1 to 2; R5 is hydrogen, fluorine, bromine, or chlorine; R6 is hydrogen, methyl or ethyl; and pharmaceutically acceptable salts thereof.