Patent ID: 7220880
Filing Date: 2007-05-22
Classification: A61P,C07C,C07D

Abstract:
1. A Compound of the structural formula I: Formula I (a) R1 is hydrogen, (b) R2′ is selected from a group consisting of C (c) R2 is selected from the group consisting of C (d) R15″ is O or NH; (e) R16″ is C (f) R7′ and R7″ are each independently selected from the group consisting of C (g) n and m are each independently selected from the group consisting of 0, 1, 2 and 3; (h) A is selected from the group consisting of (CH (i) A′ is a group consisting of C (j) R3 is selected from the group consisting of H, C (k) R4 is selected from the group consisting of H, halo, C (l) R5 and R6 are each independently selected from the group consisting of hydrogen, C (m) R4′, R5′, and R13″ are each independently a group consisting of C1-C5 alkyl, C1-C5 alkoxy, C1-C5 haloalkyl, C1-C5 haloalkoxy, nitro, cyano, CHO, hydroxy, C (n) R16′ is a group consisting of halo, C (o) R17 and R18 are each independently selected from C (p) R14 is selected from the group consisting of hydrogen, C1-C4alkyl, aryl, and arylmethyl, and which C1-C4alkyl are each independently unsubstituted or independently substituted with from one to three substituents each independently selected from the group consisting of R13′ and which arylmethyl and aryl are each independently unsubstituted or independently substituted with from one to three substituents each independently selected from the group consisting of R14′; (q) R13′ is a group consisting of C (r) R14′ is a group consisting of halo, C1-C8alkyl, C (s) a pharmaceutically acceptable salt thereof.