Patent ID: 7947835
Filing Date: 2011-05-24
Classification: A61P,C07D

Abstract:
1. A compound of Formula 2: or a pharmaceutically acceptable salt thereof or a mixture thereof, wherein R is chosen from optionally substituted cycloalkyl, optionally substituted aryl and optionally substituted heteroaryl; M is chosen from a covalent bond and —CH═CH—. Q is chosen from  wherein Z is chosen from optionally substituted phenylene and optionally substituted pyridylidene; W-D is which is optionally substituted with a group chosen from hydroxy, cyano, halo, optionally substituted lower alkyl, and optionally substituted lower alkoxy; R hydrogen, cyano, optionally substituted cycloalkyl, and optionally substituted lower alkyl; and D is a hydrogen bond donor other than hydrogen.