Patent ID: 6251362
Filing Date: 2001-06-26
Classification: A61K,A61N

Abstract:
A method of establishing the optimal effective radiation dose in mCi for treatment of disease in a patient, the method comprising the steps of:approximately identifying the lean body mass of the patient;administering a tracer dose to the patient;forming a log-linear graph indicating the fraction of injected activity versus time;establishing the rate of clearance of a tracer dose from the patient's body by reference to a range of at least 2 time points entered on said graph;identifying the effective half-life value of said tracer dose in the patient based on said rate of clearance;determining the actual amount of therapeutic mCi per cGy based on the effective half-life of said tracer in view of said lean body mass of the patient; andmultiplying said actual amount of therapeutic mCi per cGy by the amount of desired cGy to be delivered to calculate the total therapeutic mCi dose to be administered to the patient.