Patent ID: 8710233
Filing Date: 2014-04-29
Classification: A61P,C07C,C07D

Abstract:
1. A compound of formula A, in which X denotes O; Y denotes a linear or branched, saturated or unsaturated, unsubstituted or at least monosubstituted aliphatic C n denotes 1; R R R T denotes C—R R R denotes an unsaturated or saturated, unsubstituted or at least monosubstituted 3-, 4-, 5-, 6-, 7-, 8- or 9-membered cycloaliphatic residue which residue is in each case one or more of (i) attached to the parent structure via a carbon atom in the ring of the cycloaliphatic residue and may be fused with a saturated or unsaturated, unsubstituted or at least monosubstituted mono- or polycyclic ring system and (ii) attached via a linear or branched, unsubstituted or at least monosubstituted C or denotes an unsubstituted or at least monosubstituted 5- to 14-membered aryl or heteroaryl residue, which may be one or more of (i) fused with a saturated or unsaturated, unsubstituted or at least monosubstituted mono- or polycyclic ring system and (ii) attached via a linear or branched, unsubstituted or at least monosubstituted C R denote an unsaturated or saturated, unsubstituted or at least monosubstituted 3-, 4-, 5-, 6-, 7-, 8- or 9-membered cycloaliphatic residue optionally comprising at least one heteroatom as a ring member, which residue may be one or more of (i) fused with a saturated or unsaturated, unsubstituted or at least monosubstituted mono- or polycyclic ring system and (ii) attached via a linear or branched, unsubstituted or at least monosubstituted C or denote an unsubstituted or at least monosubstituted 5- to 14-membered aryl or heteroaryl residue, which may be one or more of (i) fused with a saturated or unsaturated, unsubstituted or at least monosubstituted mono- or polycyclic ring system and (ii) attached via a linear or branched, unsubstituted or at least monosubstituted C or R and R providing that R wherein unless otherwise stated, the above-stated aliphatic C the above-stated 2- to 6-membered heteroalkylene groups, C the above-stated (hetero)cycloaliphatic residues may optionally in each case be substituted with 1, 2, 3, 4 or 5 substituents mutually independently selected from the group consisting of —C the rings of the above-stated mono- or polycyclic ring systems may optionally in each case be substituted with 1, 2, 3, 4 or 5 substituents mutually independently selected from the group consisting of oxo (═O), thioxo (═S), F, Cl, Br, I, —CN, —CF and the above-stated aryl or heteroaryl residues may optionally in each case be substituted with 1, 2, 3, 4 or 5 substituents mutually independently selected from the group consisting of F, Cl, Br, I, —CN, —CF and the above-stated heteroalkylene groups in each case comprise 1, 2 or 3 heteroatom(s) mutually independently selected from the group consisting of oxygen, nitrogen (NH) and sulfur, the above-stated (hetero)cycloaliphatic residues may in each case optionally comprise 1, 2 or 3 heteroatom(s) mutually independently selected from the group consisting of oxygen, nitrogen and sulfur, the rings of the above-stated mono- or polycyclic ring systems are in each case 5-, 6- or 7-membered and may in each case optionally comprise 1, 2, 3, 4 or 5 heteroatom(s) as ring member(s), which are mutually independently selected from the group consisting of oxygen, nitrogen and sulfur, the above-stated heteroaryl residues in each case optionally comprise 1, 2, 3, 4 or 5 heteroatom(s) mutually independently selected from the group consisting of oxygen, nitrogen and sulfur as ring member(s); a steroisomer thereof, a diastereoisomer thereof, an enantiomer thereof, a racemate thereof or a salt thereof.