Patent ID: 6291508
Filing Date: 2001-09-18
Classification: A61P,C07C,C07D,G06F,Y02P

Abstract:
A polyenic carboxylic acid derivative represented by the formula (1-I) or a physiologically acceptable salt thereof:Z--(CR.sup.3.dbd.CR.sup.2).sub.n --COOR.sup.1 (1-I)wherein R.sup.1 is hydrogen or a carboxyl-protecting group; R.sup.2 and R.sup.3 are each independently hydrogen, halogen, linear lower alkyl, branched lower alkyl, linear lower alkoxy, branched lower alkoxy or aryl; n is 3 and the number of R.sup.2 's or R.sup.3 's may be the same or different from each other; andZ represents a group of the formula: ##STR281##where R.sup.a' is hydrogen, linear or branched lower alkyl, linear or branched lower alkoxy, cycloalkyl, aryl, heteroaryl or fluoroalkyl, and, R.sup.b and R.sup.c are each independently hydrogen, linear or branched lower alkyl, linear or branched lower alkoxy, cycloalkyl, aryl, heteroaryl, fluoroalkyl or halogen.