Patent ID: 9078929
Filing Date: 2015-07-14
Classification: A61K,A61P,C07K

Abstract:
1. A conjugate comprising at least one compound carrying carboxyl groups and an oligomer which consists of 10 to 1000 peptidically linked monomer units and which is either built up from more than 50% (based on the total number of monomer units) of ε-lysine monomer units or comprises at least 10 successive monomer units which are built up from at least 70% (based on the number of such successive monomer units) of ε-lysine monomer units, wherein the conjugate contains from 3 to 6 compounds carrying carboxyl groups per 10 monomer units, wherein, in the oligomer, said ε-lysine monomer units are bonded via the ε-amino group of their side chain, such that the oligomer is unbranched, wherein, in the compound carrying carboxyl groups, the proportion of carboxyl groups by molecular weight is greater than 30% and wherein at least one compound carrying carboxyl groups which is conjugated to the oligomer contains two or more free carboxyl groups.