Patent ID: 9168326
Filing Date: 2015-10-27
Classification: A61F,A61L,C07K,Y10T

Abstract:
1. A method for preparing a collagen material comprising the following steps, performed in the following order: a) preparing an aqueous solution of native or denatured collagen, wherein the aqueous collagen solution is at an acidic pH, b) adding an oxidized polysaccharide comprising an aldehyde group as a cross-linking agent that is non-reactive at acidic pH to the aqueous collagen solution of step a), c) molding or casting the aqueous collagen solution of step b), d) coagulating and cross-linking the molded or casted aqueous collagen solution of step c) by treating the molded or casted aqueous collagen solution with ammonia gas, wherein cross-linking occurs at least partially concomitantly with the coagulation of the collagen, and e) removing excess ammonia and obtaining said collagen material by drying.