Patent ID: 7422859
Filing Date: 2008-09-09
Classification: C12Q,G01N

Abstract:
1. A method for discriminating p16 INK4a overexpressing metaplasias from p16 INK4a overexpressing neoplastic or dysplastic lesions in a uterine cervix sample in the course of cytological testing procedures comprising: a. determining the presence or absence of cells overexpression of p16 b. determining the presence or absence of cells expressing at least one high risk HPV gene-product in said sample, wherein the high risk HPV gene-product is a polypeptide; and c. assessing simultaneous presence of cells expressing the high risk HPV gene-product and cells overexpressing p16 d. characterizing the simultaneous presence of cells expressing the high risk HPV gene-product and cells overexpressing p16 e. characterizing the presence of cells overexpressing p16