Patent ID: 6498178
Filing Date: 2002-12-24
Classification: A61P,C07B,C07C,C07D,C07F

Abstract:
A compound of formula (A): wherein:wherein R1 and R2 are taken together to form tetrahydrofuranyl, wherein one hydrogen atom in said tetrahydrofuran is replaced by â€”OR6; R6 is selected from â€”C(O)â€”CH3, â€”CH2-C(O)â€”OH, â€”CH2â€”C(O)â€”Oâ€”tBu, â€”CH2â€”CN, or â€”CH2â€”Câ‰¡CH; R9 is hydrogen; R10 is selected from â€”Câ‰¡N or 5-oxazolyl; and R11 is selected from halo, â€”Oâ€”(C1-C3) straight alkyl, or â€”Oâ€”(C2-C3) straight alkenyl or alkynyl.