Patent ID: 6416953
Filing Date: 2002-07-09
Classification: B01J,B82Y,C12Q,G06N,G11B,G11C,H01L,Y10S,Y10T

Abstract:
A biosensor for detecting the presence of an analyte in solution, said analyte comprising a target DNA sequence, said biosensor comprising:an excitation source for delivering emitting photonic energy; a donor sequence comprising a first polynucleotide having a terminal donor chromophore and at least one intermediate donor chromophore linked to said first polynucleotide by linker arms, wherein said first polynucleotide is complementary to a first region of said target DNA sequence; an acceptor sequence comprising a second polynucleotide having at least one acceptor chromophore linked to said second polynucleotide by linker arms, wherein said second polynucleotide is complementary to a second region of said target DNA sequence; wherein the distance between one said donor chromophore and one said acceptor chromophore is such that they are in an energy transfer relationship; and an associated photon sensing means to detect photonic energy emitted from said acceptor.