Patent ID: 8404216
Filing Date: 2013-03-26
Classification: A61K,A61P,C07C,C07D,C07F,C08G

Abstract:
1. A dendritic chelated complex of the following formula I: wherein: M is a magnetic or scintigraphic marker, C is a chelating agent for the magnetic marker M, [MC] is a chelate of the magnetic-marker M, E is a spacer, n=0 or 1, [D] is a dendritic structure, the core of which comprises at least one group derived from benzyl alcohol or from a benzyl amine, the benzyl ring of which is substituted at positions 3, 4, 5 with chains composed of polyethylene glycol units, m is an integer equal to 1 or 2 or 4, X p1 is an integer equal to 0 to 12, limits included, X p2 is an integer equal to 0, 1, 2 or 4, limits included, X p3 is an integer equal to 0, 1, 2 or 4, limits included, X p1+p2+p3+p4=3 when m=1 or p1+p2+p3+p4=6 when m=2 or p1+p2+p3+p4=12 when m=4, p4 is an integer equal to 0 to 12, limits included, B is a counterion, z is an integer equal to 0, 1, 2, 3 or 4.