Patent ID: 6784165
Filing Date: 2004-08-31
Classification: A61K

Abstract:
A method for the treatment of heart rhythm disturbances in a human in need thereof that would benefit from the induction of negative dromotropic and/or negative chronotropic actions, comprising the administration to said human an effective amount of a compound of the Formula: or a pharmaceutically acceptable salt or ester thereof, whereinR1 is C3-7 secondary alkyl, C3-8 cycloalkyl, or C7 bicycloalkyl; and R2 is C1-4 alkyl, C1-4 hydroxyalkyl or C3-5 cycloalkyl; wherein said effective amount produces the desired therapeutic effect, andwherein the effective amount is administered orally or intravenously in the amount of 0.001-100 &mgr;g/kg.