Patent ID: 7553489
Filing Date: 2009-06-30
Classification: A61K,A61P,C07K

Abstract:
1. An antibody that immunospecifically binds to a respiratory syncytial virus (RSV) F antigen, wherein the antibody comprises: (a) a variable light (VL) chain having the amino acid sequence of SEQ ID NO:257; (b) a VL domain having the amino acid sequence of SEQ ID NO:76; (c) a variable heavy (VH) chain having the amino acid sequence of SEQ ID NO:256, and (d) a VH domain having the amino acid sequence of SEQ ID NO:48, and (e) a VH chain having the amino acid sequence of SEQ ID NO:256, and (f) a VH domain having the amino acid sequence of SEQ ID NO:48, and (g) a VH chain or VH domain comprising a VH complementary determining region (CDR) 1 having the amino acid sequence of SEQ ID NO:10, a VH CDR2 having the amino acid sequence of SEQ ID NO:19, a VH CDR3 having the amino acid sequence of SEQ ID NO:20, and (h) a VH chain having the amino acid sequence of SEQ ID NO:256, and (i) a VH domain having the amino acid sequence of SEQ ID NO:48, and (j) a VH chain or VH domain comprising a VH CDR1 having the amino acid sequence of SEQ ID NO:10, a VH CDR2 having the amino acid sequence of SEQ ID NO:19, a VH CDR3 having the amino acid sequence of SEQ ID NO:20, and (k) a VH chain or VH domain comprising a VH CDR1 having the amino acid sequence of SEQ ID NO:10, a VH CDR2 having the amino acid sequence of SEQ ID NO:19, a VH CDR3 having the amino acid sequence of SEQ ID NO:20, and