Patent ID: 6034221
Filing Date: 2000-03-07
Classification: A61P,C07K

Abstract:
Highly purified albumin which is at least 99.5% monomeric and has at least one purity characteristic selected from the group consisting of an aluminum ion content of less than 150 ng; an iron ion content of less than 3,000 ng; a copper ion level of less than 10,000 ng; a magnesium ion level of less than 3,000 ng; a zinc ion level of less than 5,000 ng; a manganese ion level of less than 50 ng, all based on one gram of albumin; a glycation level of less than 0.6 moles hexose/mole protein; a level of low molecular weight contaminants of below 20 V.sec; a single peak on a capillary zone electrophoretogram; an intact C-terminus; a free thiol content of at least 0.85 mole SH/mole protein and substantially no C-18 or C-20 fatty acids, except that if the albumin has less than 3000 ng iron/g albumin, then it must also have at least one other of the said purity characteristics.