Patent ID: 7435744
Filing Date: 2008-10-14
Classification: A61P,C07D

Abstract:
1. A compound comprising a structure of formula (I): wherein: V and U: together form a group that contains one or more heteroatoms, and that taken together with one or more: (a) hydrogen atoms; (b) carbon atoms; (c) —CH═ groups; (d) —CH (e) additional heteroatoms of the same or different type; or any combination thereof, form a 4-7 membered homocyclic or heterocyclic ring, wherein the heterocyclic ring is selected from the group consisting of morpholine, pyrrole, pyrrolidine, oxo-pyrrolidine, thioxo-pyrrolidine, pyrazole, pyrazolidine, imidazole, oxo-imidazole, thioxo-imidazole, imidazolidine, oxo-imidazolidine, thioxo-imidazolidine, 1,4-oxazine, oxazole, oxazolidine, oxo-oxazolidine, thioxo-oxazolidine or 3-oxo-1,4-oxazine; W: —CO—, —CH X: —CO—; Y: is —O—, C Z: is hydrogen, halogen, nitro, amino, C R n and m: independently are 0-3, wherein n and m cannot each be 0, and wherein m+n=4; or an optical antipode, racemate or pharmaceutically-acceptable salt thereof.