Patent ID: 6194434
Filing Date: 2001-02-27
Classification: A61P,C07D

Abstract:
A compound represented by the formula (I) or a salt thereof: ##STR6##whereinR.sup.1 represents a substituted cyclic alkyl group having 3 to 6 carbon atoms;R.sup.2 represents a hydrogcn atom, an amino group, a hydroxyl group, a thiol group, a halogenomethyl group, an alkyl group having 1 to 6 carbon atoms, an alkenyl group having 2 to 6 carbon atoms, an alkynyl group having 2 to 6 carbon atoms, or an alkoxyl group having 1 to 6 carbon atoms, and wherein said amino group may have at least one substituent selected from the group consisting of a formyl group, an alkyl group having 1 to 6 carbon atoms and an acyl group having 2 to 5 carbon atoms;R.sup.3 represents an amino group, a halogenomcthyl group, a halogenomethoxyl group, an alkenyl group having 2 to 6 carbon atoms, or an alkynyl group having 2 to 6 carbon atoms, and wherein said amino group may have at least one substituent selected from the group consisting of a formyl group, an alkyl group having 1 to 6 carbon atoms and an acyl group having 2 to 6 carbon atoms;R.sup.4 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, and wherein said alkyl group may have at least one substituent selected from the group consisting of a hydroxyl group, a halogen atom, an alkylthio group having 1 to 6 carbon atoms and an alkyloxyl group having 1 to 6 carbon atoms;R.sup.5 represents a cyclic alkyl group having 3 to 6 carbon atoms;X represents a halogen atom or a hydrogen atom; andY represents a hydrogen atom, a phenyl group, an acetoxymethyl group, a pivaloyloxymethyl group, an ethoxymethyl group, a choline group, a dimethylaminoethyl group, a 5-indanyl group, a phthalidinyl group, a 5-alkyl-2-oxo-1,3-dioxol-4-ylmethyl group, a 3-acetoxy-2-oxobutyl group, an alkyl group having 1 to 6 carbon atoms, an alkoxymethyl group having 2 to 7 carbon atoms, or a phenylalkyl group having 1 to 6 carbon atoms in the alkyl moiety thereof.