Patent ID: 8236781
Filing Date: 2012-08-07
Classification: A61K,A61P,A61Q

Abstract:
1. A hydrogel of chitosan carboxyalkylamide, having a pH value between 6.5 and 7.2, said chitosan carboxyalkylamide being constituted by from 40 to 90 mole %, relative to the total number of (A) and (B) units, of D-glucosamine N-carboxyalkylamide units of formula (I) ((A) units) where n represents an integer ranging from 1 to 8, or a physiologically acceptable base addition salt thereof, from 60 to 10 mole %, relative to the total number of (A) and (B) units, of protonated D-glucosamine units of formula (II) ((B) units) and 5.5 obtained by the addition of an organic acid of formula R—COOH, where R represents a C reaction of the acid addition salt of chitosan in aqueous solution thus obtained with 0.5 to 1 mole, per mole of D-glucosamine units ((B) units), of an anhydride of an organic diacid of formula HOOC—(CH adjustment of the pH of the reaction solution thus obtained to a value between 6.5 and 7.2 by the addition of a physiologically acceptable base.