Patent ID: 9206173
Filing Date: 2015-12-08
Classification: A61K,A61P,C07D

Abstract:
1. A heterocyclic compound represented by general formula (1) wherein, R (1) a phenyl group (2) a naphthyl group (3) a dihydroindenyl group (4) a phenyl lower alkyl group (5) a pyridyl group (6) a pyridazinyl group (7) a triazolyl group (8) a pyrimidinyl group (9) an imidazolyl group (10) a dihydropyridyl group (11) a quinolyl group (12) an isoquinolyl group (13) a tetrahydroquinolyl group (14) a dihydroquinolyl group (15) an imidazopyridyl group (16) a pyrazolopyridyl group (17) an indolinyl group (18) a naphthyridinyl group (19) a benzoimidazolyl group (20) an indolizinyl group (21) a thienyl group (22) a benzothienyl group (23) a benzodioxolyl group (24) a benzofuryl group (25) a thienopyridyl group (26) a thienopyrrolyl group (27) a dihydrobenzothiazinyl group (28) an isoxazolyl group (29) a tetrahydrobenzoxazepinyl group (30) an indolyl group (31) a benzothiazolyl group (32) a dihydrothienodioxinyl group (33) a pyrrolidinyl group (34) a dihydrobenzoxazinyl group (35) a tetrahydroquinazolinyl group (36) a tetrahydroquinoxalinyl group (37) a dihydrobenzodioxinyl group (38) a chromanyl group (39) a dihydropyridooxazinyl group (40) a tetrahydronaphthyl group (41) a dihydrobenzofuryl group (42) a dihydrobenzoxazolyl group (43) a tetrahydrobenzothienyl group (44) a tetrahydrocyclopentapyrazolyl group (45) a benzotriazolyl group (46) a dihydrobenzoimidazolyl group (47) a dihydrobenzothiazolyl group (48) an isoindolinyl group (49) a tetrahydrobenzodiazepinyl group (50) a dihydrobenzodioxepinyl group (51) a quinoxalinyl group (52) an indazolyl group (53) a cinnolinyl group (54) a dihydrophthalazinyl group (55) a dihydronaphthyridinyl group (56) a hexahydroquinolinyl group (57) a furopyrrolyl group (58) a thienopyrazinyl group (59) an imidazothiazolyl group (60) a xanthenyl group (61) a piperidinyl group (62) a pyrrolyl group (63) a pyrazolyl group (64) a thiazolyl group (65) a furyl group (66) a pyrazinyl group (67) a dihydropyrazolyl group (68) a thiazolidinyl group (69) a tetrahydrofuranyl group (70) a tetrahydropyranyl group (71) a thiadiazolyl group (72) a dihydropyridazinyl group (73) a thienyl lower alkyl group (74) a cyclo C3-C8 alkyl group (75) a lower alkyl group (76) a benzodioxolyloxy group (77) a phenylthio lower alkyl group (78) a phenylcyclo C3-C8 alkyl group (79) a phenoxy lower alkyl group (80) a phenyl lower alkenyl group (81) a cyclo C3-C8 alkyl lower alkenyl group (82) a pyridyl lower alkyl group (83) a benzofuryl lower alkenyl group (84) a dihydrobenzofuryl lower alkenyl group (85) a dihydrobenzodioxinyl lower alkenyl group (86) a dihydrobenzodioxinyloxy lower alkyl group (87) an oxazolyl group (88) a dihydroindenyloxy lower alkyl group (89) a dihydropyrimidinyl group (90) a pyridyloxy lower alkyl group (91) a lower alkoxy lower alkyl group; (1-1) a halogen atom (1-2) a lower alkyl group (1-3) a lower alkanoyl group (1-4) a halogen-substituted lower alkyl group (1-5) a halogen-substituted lower alkoxy group (1-6) a cyano group (1-7) a lower alkoxy group (1-8) a lower alkylthio group (1-9) an imidazolyl group that may have a lower alkyl group(s) (1-10) an oxazolyl group (1-11) an oxadiazolyl group that may have a lower alkyl group(s) (1-12) a triazolyl group (1-13) a benzoyl group (1-14) a pyridyl group (1-15) an oxo group (1-16) a phenyl group that may have a substituent(s) selected from the group consisting of a lower alkyl group, a halogen-substituted lower alkoxy group, a halogen-substituted lower alkyl group and a halogen atom (1-17) a thienyl group (1-18) a furyl group (1-19) a thiazolyl group (1-20) a triazolyl lower alkyl group (1-21) a cyclo C3-C8 alkyloxy group (1-22) a phenyl lower alkyl group (1-23) a phenoxy group (1-24) a cyclo C3-C8 alkyl group (1-25) a pyrazolyl group (1-26) a pyrrolyl group (1-27) a lower alkenyl group (1-28) a pyrrolidinyl group that may have an oxo group(s) (1-29) a dihydropyrazolyl group that may have a substituent(s) selected from the group consisting of an oxo group and a lower alkyl group (1-30) a hydroxy group (1-31) a tetrazolyl group (1-32) a morpholinyl group (1-33) a pyrimidinyl group (1-34) a homo-piperazinyl group that may have a lower alkyl group(s) (1-35) a lower alkanoylamino group (1-36) a cyclo C3-C8 alkylcarbonylamino group (1-37) a phenoxy lower alkyl group (1-38) a thiomorpholino group (1-39) a piperidinyl group (1-40) a lower alkoxy lower alkyl group (1-41) an amino group that may have a substituent(s) selected from the group consisting of a lower alkyl group, a lower alkanoyl group and a cyclo C3-C8 alkyl group (1-42) a morpholinyl lower alkyl group (1-43) a piperidinyl lower alkyl group (1-44) a lower alkylsulfonyl group (1-45) an adamantyl lower alkyl group (1-46) a carbamoyl group that may have a lower alkyl group(s) or a salt thereof.