Patent ID: 6426345
Filing Date: 2002-07-30
Classification: A61P,C07D

Abstract:
A compound of the formula: whereinR1 is aryl which may have suitable substituent(s), ar(lower)alkyl which may have suitable substituent(s), halo(lower)alkyl, carboxyethyl, protected carboxy(lower)alkyl, acyl(lower)alkyl, a heterocyclic group which may have suitable substituent(s) or a heterocyclic(lower)alkyl group which may have suitable substituent(s), R2 is aryl which may have suitable substituent(s) or a heterocyclic group, and R3 is hydrogen, lower alkoxy or arylthio, and a pharmaceutically acceptable salt thereof, provided that when R1 is phenyl, halophenyl, trihalo(lower)alkyl, carboxyethyl, piperidyl, morpholinyl, piperazinyl, or alkylpiperazinyle, then R2 is not substituted phenyl, piperidyl, morpholinyl, piperazinyl, or alkylpiperazinyl.