Patent ID: 9155754
Filing Date: 2015-10-13
Classification: A61K,A61P,C12N,C12Y

Abstract:
1. A method of upregulating a function of and/or the expression of an ABCA1 polynucleotide having SEQ ID NO: 1 in patient cells or tissues in vivo or in sum comprising: contacting said cells or tissues with at least one modified single stranded antisense compound of 12 to 30 nucleotides in length that targets and specifically hybridizes to a complementary region of a natural antisense polynucleotide of the ABCA1 polynucleotide having SEQ ID NO: 8 or 9; thereby upregulating function of and/or the expression of the ABCA1 polynucleotide in patient cells or tissues in vivo or in vitro.