Patent ID: 6548546
Filing Date: 2003-04-15
Classification: A61P,C07C,C07D

Abstract:
A compound of the formula or a tautomer thereof, wherein:(a) R1 is phenyl, wherein said phenyl is substituted from 1-3 times with R2, or R1 is naphthyl, wherein said naphthyl is optionally substituted from 1-3 times with R2; (b) each R2 is independently selected from halo, C1-C3 alkyl, C1-C2 alkoxy, C1-C3 haloalkyl, and phenyl-(CH2)mOnâ€”; (c) m is 0 or 1; (d) n is 0 or 1; and (e) Z is methylene or â€”C(O)â€”, provided that when Z is methylene said substituted phenyl is not para-methoxy phenyl or when Z is â€”C(O)â€” said substituted phenyl is not ortho-chloro phenyl, or a pharmaceutically acceptable salt, solvate or prodrug of said compound or tautomer thereof.