Patent ID: 6291193
Filing Date: 2001-09-18
Classification: A61K,C07K,C12N

Abstract:
A method for identifying a compound which binds to an isolated mammalian T-box transcription factor polypeptide, wherein said polypeptide is encoded by a nucleic acid molecule which hybridizes to a complement of a nucleic acid molecule comprising SEQ ID NO:1 at 6.times.SSC at 45.degree. C., followed by one or more washes in 0.2.times.SSC, 0.1% SDS at 50-60.degree. C., said method comprising:a) contacting the mammalian T-box transcription factor polypeptide, or a cell expressing the mammalian T-box transcription factor polypeptide with a test compound; andb) determining whether the mammalian T-box transcription factor polypeptide binds to the test compound.