Patent ID: 6277992
Filing Date: 2001-08-21
Classification: A61P,C07B,C07D

Abstract:
A camptothecin compound having a substituent on the 20-hydroxy group of the formula (XV): ##STR64##wherein R.sup.0 is a group of the following structure (XIX): ##STR65##wherein Y is a substituted or unsubstituted arylsulfonyl group or an alkylsulfonyl group and n is 0 or 1,and the groups R.sup.5 -R.sup.9 are as defined below:R.sup.5 is an ethyl group,R.sup.6 is a hydrogen atom,R.sup.7 is a --O(CH.sub.2).sub.3 NH.sub.2 group, which may be protected by a --COOC(CH.sub.3).sub.3 group,R.sup.8 is a hydrogen atom,R.sup.9 is a hydrogen atom.