Patent ID: 6623749
Filing Date: 2003-09-23
Classification: A61B,A61K,A61L,A61P,C08G,C12N,C12P,Y10S,Y10T

Abstract:
A biocompatible medical device comprisinga polyhydroxyalkanoate which does not elicit an acute inflammatory response when implanted into an animal, wherein the polyhydroxyalkanoate is prepared by a process that introduces pyrogen into the polyhydroxyalkanoate such that the polyhydroxyalkanoate contains an endotoxin and the endotoxin is removed to less than 20 units/grain of polyhydroxyalkanoate by treating the polyhydroxyalkanoate with an oxidizing agent to remove the endotoxin but not to adversely affect the polybydroxyalkanoate's inherent chemical structures and physical properties.