Patent ID: 8815953
Filing Date: 2014-08-26
Classification: A61K,A61P

Abstract:
1. A topically applicable pharmaceutical formulation suitable for treatment of a dermatological condition comprising, a) from about 0.01 to 2% (w/w) of menadione; b) from about 1 to 50% (w/w) of a lipophilic component selected from the group consisting of isopropyl myristate, caprylic/capric triglyceride, diethyl sebacate, diisopropyl adipateand combinations thereof; c) from about 0.01 to 5% (w/w) each of one or more acrylic acid based polymers; e) from about 0.03 to 10% (w/w) of a preservative; f) a neutralizing agent sufficient to maintain a pH of about 4.0 to 7.0; and g) water; wherein the formulation delivers a concentration of about 0.1 to 1.5 mM vitamin K3 to the epidermal skin layer when applied topically.