Patent ID: 6451852
Filing Date: 2002-09-17
Classification: C07C

Abstract:
A method to supress immune response in a subject susceptible to or afflicted with an autoimmune or inflammatory disease, said method comprising administering to said subject a therapeutically-effective amount of an immunosuppressive compound of Formula II: wherein m is one or two; wherein n is a number selected from one to five, inclusive; wherein R1 is selected from hydrido, alkoxyalkyl, alkenyl and alkynyl; wherein R6 is selected from loweralkyl; wherein each of R8, R9, R10 and R12 through R16 is independently selected from hydrido, hydroxy, alkoxy, alkenyl, alkynyl, alkylcarbonyl, alkoxycarbonyl and alkoxyalkyl; with the proviso that at least one of R12 and R16 must be selected from alkoxycarbonyl or a tautomer thereo or a pharmaceutically-acceptable salt thereof.