Patent ID: 7115637
Filing Date: 2006-10-03
Classification: A61P,C04B,C07D

Abstract:
1. A method of treating inflammatory diseases selected from cerebral ischemia, reperfusion/ischemia in stroke, myocardial ischemia, renal ischemia, rheumatoid arthritis, or Crohn's disease in a patient, said method comprising administering to said patient a compound of the formula: wherein each of Q the rings that make up Q the rings that make up Q Q R′ is selected from hydrogen; (C R R R W is selected from N(R W′ is selected from N(R each R is independently selected from hydrogen, —R R Y is C; Z is CH, N, C(OCH U is selected from R or W; V is selected from —C(O)NH J is a (C D is selected from T is O or NH; and G is NH provided that in compounds of formula (Ia), when W is hydrogen, Z is CH or N, and V is —C(O)NH in compounds of formula (Ia), when W is hydrogen; Z is CH or N; V is —C(O)NH