Patent ID: 8318170
Filing Date: 2012-11-27
Classification: A61K,A61P,C07K,C12Q,G01N

Abstract:
1. A method of treating a mammal with inflammatory disease, comprising: a) exposing a tissue sample from said mammal to an antibody which binds specifically to CXCL9, or an antibody which binds specifically to CXCL11, or both antibodies; b) determining a level of expression of CXCL9, or CXCL11 or both based on binding of said antibody to said tissue sample; and c) if over-expression of CXCL9 or CXCL11 or both are detected in said tissue sample of said mammal, administering to said mammal an effective amount of an antibody which binds specifically to CXCL9, or an antibody which binds specifically to CXCL11, or both antibodies for the treatment of said inflammatory disease.