Patent ID: 7786156
Filing Date: 2010-08-31
Classification: C07D,Y02P

Abstract:
1. A process for the manufacture of a 1,2,4-triazol-1-yl compound of the formula [A] or a salt thereof, wherein each of R3 and R4 is independently hydrogen or a lower alkyl with up to and including maximally 7 carbon atoms, said process comprising the steps of: reacting with a 1,2,4-triazolyl forming reagent a hydrazine compound of the formula [B] or a salt thereof, wherein R is hydrogen or acyl, R2 is hydrogen, each of R3 and R4 is independently hydrogen or a lower alkyl with up to and including maximally 7 carbon atoms, and R6 is hydrogen, further wherein, if R is acyl in formula [B], optionally removing an acyl group R before reacting the compound of the formula [B] with the 1,2,4-triazolyl forming reagent, removing any protecting group R2 and removing any group COOR7 to produce the compound of the formula [A], or a salt thereof.