Patent ID: 8614261
Filing Date: 2013-12-24
Classification: G02B

Abstract:
1. A silicone hydrogel contact lens comprising an ophthalmically compatible, cast molded lens body having an oxygen permeability of greater than 110 barrers, an equilibrium water content of at least 40% by weight, and a modulus in a range of 0.5 MPa to 1.0 MPa, wherein the lens body comprises a polymerized reaction product of a precursor composition comprising at least one siloxane-containing monomer or macromer, a hydrophilic monomer, a hydrophobic monomer, and a crosslinkable monomer, the siloxane-containing monomer or macromer contains a polysiloxane-dimethacrylate represented by formula (I) wherein, X 1 is a polymerizable substituent having the following formula: wherein, R1, R2, R3 and R4 are groups independently selected from hydrocarbon groups having 1 to 12 carbon atoms and a siloxanyl group; [Y1] is a polysiloxane backbone comprising not less than 2 siloxane units; R5 is a hydrogen or a methyl group; Z1 is a group selected from —NHCOO—, —NHCONH—, —OCONH—R6-NHCOO—, —NHCONH—R7-NHCONH— and —OCONH—R8-NHCONH—, with R6, R7 and R8 independently selected from hydrocarbon groups having 2 to 13 carbon atoms; m is an integer from 0 to 10; n is an integer from 3 to 10; p is 0 when m is 0 and p is 1 when m is 1 or greater; and q is an integer from 0 to 20, wherein the amount of said polysiloxane-dimethacrylate is from about 30% to about 70% by weight based on the precursor composition, the hydrophilic monomer contains N-vinyl 2-pyrrolidinone and 2-hydroxybutyl methacrylate, wherein the amount of the N-vinyl 2-pyrrolidinone is from about 5% to about 50% by weight based on the precursor composition, and the amount of the 2-hydroxybutyl methacrylate is up to about 15% by weight based on the precursor composition, and the crosslinkable monomer contains one or more allyl groups, wherein the amount of the crosslinkable monomer which contains one or more allyl groups is from about 0.005% to about 5% by weight based on the precursor composition.