Patent ID: 6410685
Filing Date: 2002-06-25
Classification: A23L,A61K,A61P

Abstract:
A method of mitigating at least one symptom of stress in a mammal, wherein said symptom is selected from the group consisting of (a) reduction of noradrenaline production, (b) reduction of dopamine production, (c) reduction of interleukin-2 production (d) a decrease in the weight of the thymus and spleen, (e) a decrease in mitogen reactivity of spleen cells, and (f) a decrease in the Fischer ratio, said method comprising administering the tripeptide Ile-Pro-Pro or the tripeptide Val-Pro-Pro to a mammal which has been subjected to stress for a time and under conditions effective to increase noradrenaline production, increase dopamine production, increase interleukin-2 production, increase the weight of the thymus and spleen, increase the mitogen reactivity of spleen cells, or increase the Fischer ratio, wherein the Fischer ratio is the ratio of branched-alkyl to aromatic amino acids.