Patent ID: 6541426
Filing Date: 2003-04-01
Classification: A01N,A61K,Y10S

Abstract:
A method to form a suspension concentrate of a crystalline solid with a particle size of 5 microns or less, comprising the steps of:a) combining a stream comprising melted solid with a stream comprising a solvent; wherein: 1) the melting point of the solid is from 40 to 120Â° C.; 2) the temperature of the stream comprising melted solid is 5Â° C. or more above the melting point of the solid; 3) the solid has a solubility of less than 1%, by weight, in the solvent at 25Â° C.; 4) one or both of the streams further comprises a surfactant or dispersant or both; and b) mixing the combined streams in a confined chamber under high shear conditions wherein the melted solid first emulsifies forming particles 5&mgr; or less in size which then cool to below their melting point and solidify before the particles leave the chamber and wherein the residence time of the combined solid and solvent streams in the confined chamber is 5 seconds or less.