Patent ID: 9206253
Filing Date: 2015-12-08
Classification: A61K,A61P,C07K,G01N

Abstract:
1. A host cell that produces an isolated antibody or antigen-binding portion thereof comprising at least one of the following combinations of complementary determining region (CDR) sequences: 1) 11E12: variable heavy (VH)-CDR1 of SEQ ID NO: 1, VH-CDR2 of SEQ ID NO: 4, VH-CDR3 of SEQ ID. NO: 7, variable light (VL)-CDR1 of SEQ ID NO: 10, VL-CDR2 of SEQ ID NO: 13, and VL-CDR3 of SEQ ID NO: 16; 2) 19D07: VH-CDR1 of SEQ ID NO: 2, VH-CDR2 of SEQ ID NO: 5, VH-CDR3 of SEQ ID NO: 8, VL-CDR1 of SEQ ID NO: 11, VL-CDR2 of SEQ ID NO: 14, and VL-CDR3 of SEQ ID NO 17; or 3) 34D03: VH-CDR1 of SEQ ID NO: 3, VH-CDR2 of SEQ ID NO: 6, VH-CDR3 of SEQ ID NO: 9, VL-CDR1 of SEQ ID NO: 12, VL-CDR2 of SEQ ID NO: 15, and VL-CDR3 of SEQ ID NO: 18.