Patent ID: 6197524
Filing Date: 2001-03-06
Classification: A61K,A61P,C07K,C12N,G01N,Y10S

Abstract:
A method for diagnosing a Th1-mediated disease or disorder, comprising the steps of:reacting a sample of human fluid, derived from an individual suspected to suffer from a Th1-mediated disease, with an antibody, or fragment thereof, specific for soluble LAG-3; andmeasuring the amount of soluble LAG-3 that is bound to the soluble LAG-3 specific antibody, or a fragment thereof, wherein an elevated amount of soluble LAG-3 relative to the amount of soluble LAG-3 in a sample of human fluid derived from an individual not suffering from a Th1-mediated disease or disorder is diagnostic for the presence of a Th1-mediated disease or disorder.