Patent ID: 6780611
Filing Date: 2004-08-24
Classification: A61K,A61P,C07K

Abstract:
An isolated or purified polynucleotide comprising a polynucleotide selected from the group consisting of:(a) a polynucleotide encoding the polypeptide of SEQ ID NO: 2; (b) a polynucleotide of SEQ ID NO: 1; (c) a polynucleotide contained in the clone deposited as National Collections of Industrial and Marine Bacteria Limited (NCIMB) 41066; and (d) a polynucleotide comprising a nucleotide sequence that has at least 95% identity to the polynucleotide of any one of (a) to (c) and encodes a neuromedin U receptor that mediates, in HEK-293 cells transfected with and expressing said polynucleotide, a specific, neuromedin U-induced increase in intracellular calcium following contact with neuromedin U.