Patent ID: 7560473
Filing Date: 2009-07-14
Classification: A61K,A61P,C07C,C07D

Abstract:
1. An amine derivative represented by formula I a , its racemes or optical isomers, its pharmaceutical acid addition salts or its amides or esters, wherein, (1) when R′ (2) when each of R′ I′ a , racemes or optical isomers thereof, wherein each of R and R′ represents C when R′ or when R′ or when R′ or when R′ or when R′ and each of R′ 2 and R′ 3 represents methyl, or R′ 2 and R′ 3 together represent —(CH 2 ) 4 —or (CH 2 ) 5 —, R′ 4 represents (CH 3 ) 2 CH—; or when R′ and each of R′ 2 and R′ 3 represents methyl, R′ 4 represents (CH 3 ) 2 CH—or (CH 3 ) 2 CH(CH 3 )—; or when R′ and each of R′ 2 and R′ 3 represents (CH 2 ) 5 —, R′ 4 represents (CH 3 ) 2 CCH(CH 3 )—; or (4) when R′ or when R′ or when R′ methyl, R′ 4 may represent or (5) when R′ when R′ when R′ when R′