Patent ID: 8025901
Filing Date: 2011-09-27
Classification: A61K,A61L,C08G,C08L,Y10S

Abstract:
1. A method of administering pharmacologically-active agents or cells to a patient in need thereof, the method comprising administering a hydrogel to a patient in need of the pharmacologically-active agent or cells, wherein the pharmacologically-active agent or living cells are entrained within the hydrogel, and the hydrogel comprises: a first polymer matrix containing reactive amino acid moieties; a second polymer matrix that interpenetrates with the first polymer matrix; a bifunctional modifier comprising a compound of formula: wherein at least one of the “A” or “Z” moieties is covalently bonded to the reactive amino moieties of the polymer matrix; and wherein “A” and “Z” are independently selected from the group consisting of hydrogen, halo, hydroxy, C “m” is an integer of from 2 to 8; and “n” is an integer equal to or greater than 100.