Patent ID: 8952013
Filing Date: 2015-02-10
Classification: A61K,A61P

Abstract:
1. A sterile frozen controlled release aripiprazole formulation which comprises: (a) aripiprazole having a mean particle size of about 1 to 10 microns, and (b) one or more suspending agents, wherein said sterile frozen controlled release aripiprazole formulation is obtained by freezing a homogeneous aqueous suspension comprising (a) and (b), and wherein upon drying to form a cake and reconstitution, which comprises adding water to said cake, a sterile injectable formulation is obtained which is a homogeneous suspension and which contains from about 0.1 to about 600 mg of aripiprazole per mL, and wherein upon injection into a subject, said sterile injectable formulation releases aripiprazole over a period of at least about two weeks from the date of administration.