Patent ID: 6274594
Filing Date: 2001-08-14
Classification: A61P,C07D

Abstract:
A compound of formula (I) or pharmaceutically acceptable salt thereof: ##STR8##where X and Q are independently a bond, methylene or ethylene groups such the ring structure Z is a five or six membered ring,R.sup.1 is hydrogen or C.sub.1-6 alkyl,R.sup.2 is hydrogen or up to four substituents independently selected from halogen, CF.sub.3, NO.sub.2, CN, N.sub.3, C.sub.1-6 alkylO--, C.sub.1-6 alkylS--, C.sub.1-6 alkyl, C.sub.3-6 cycloalkyl, C.sub.3-6 cycloalkyl-C.sub.1-4 alkyl-, C.sub.1-6 alkenyl, C.sub.1-6 alkynyl, CF.sub.3 CO--, CF.sub.3 O, C.sub.1-6 alkylCO--, C.sub.3-6 cycloalkylCO--, C.sub.3-6 cycloalkyl-C.sub.1-4 alkylCO--, phenyl, phenoxy, benzyloxy, benzoyl, phenyl-C.sub.1-4 alkyl-,or --NR.sup.4 R.sup.5 where R.sup.4 is hydrogen or C.sub.1-4 alkyl, andR.sup.5 is hydrogen, C.sub.1-4 alkyl, --CHO, --CO.sub.2 C.sub.1-4 alkyl or --COC.sub.1-4 alkyl, andR.sup.3 is hydrogen or up to two C.sub.1-6 alkyl groups.