Patent ID: 7365085
Filing Date: 2008-04-29
Classification: A61P,C07C,C07D

Abstract:
1. A compound of Formula I: wherein: X is selected from C or X and an adjacent R Z is CH, CR Y is selected from —O—, —S—, —N(R W W W Q is selected from C p is 0-8; n is 3; m is 0 or 1; q is 0 or 1; t is 0 or 1; each R each R each R R R R each R R R R R wherein each Ar or aryl independently represent a substituted or unsubstituted carbocyclic aromatic group, which may be optionally fused to another carbocyclic aromatic group moiety or to a cycloalkyl group moiety, wherein said Ar or aryl is optionally substituted by one or more of the substituents independently selected from the group halo, cyano, C each Het independently represents a monocyclic 5- to 7-membered, a bicyclic 7- to 10-membered or a tricyclic 11- to 18-membered heterocyclic ring group which is saturated, unsaturated or aromatic, and consists of carbon atoms and from one to three heteroatoms selected from N, O and S, wherein the N or S heteroatoms of said Het are optionally oxidized or the N heteroatom is optionally quaternized, wherein said Het is optionally unsubstituted or substituted by one or more of the substituents independently selected from the group halo, cyano, C provided that X is not COOR provided that the compound is not 5-[3-[[(3,4-dichlorophenyl)methyl][2-(2-naphthalenyl)ethyl]amino]propoxy]-3-methoxy-1,2-benzenedicarboxylic acid, or 5-[3-[[(3,4-dichlorophenyl)methyl][2-(2-naphthalenyl)ethyl]amino]propoxy]-3-methoxy-1,2-benzenedicarboxylic acid, dimethyl ester; or a pharmaceutically acceptable salt or hydrate thereof.