Patent ID: 7332159
Filing Date: 2008-02-19
Classification: A61K,A61P,C12Y,Y10S

Abstract:
1. A nanoparticle composition for sustained release of an effective amount of a therapeutically active agent, said composition comprising a therapeutically active polypeptide as said active agent, at least one biodegradable polymer, a plasticizer, and a targeting moiety, wherein said biodegradable polymer is selected from the group consisting of a poly(lactide-co-glycolide), poly(lactic acid), poly(alkylene glycol), polybutylcyanoacrylate, poly(methylmethacrylate-co-methacrylic acid), poly-alkylamine, polyanhydride, polyhydroxybutyric acid, and a polyorthoester, wherein said targeting moiety comprises SEQ ID NO: 2, and wherein said plasticizer comprises L-tartaric acid dimethyl ester.