Patent ID: 6669954
Filing Date: 2003-12-30
Classification: A61K

Abstract:
A drug delivery system comprising:(a) a therapeutic amount of a pharmaceutical agent; (b) a container having (i) at least one aperture and (ii) a wall having an inside and an outside; (c) an excipient formulation disposed in said container regulating a diffusional boundary for said pharmaceutical agent, wherein the diffusional boundary layer is confined within said container for a period of time to allow drug delivery to a desired location and continuously releasing said pharmaceutical agent upon solvation at a rate of less than one-fifth of the initial release of said pharmaceutical agent in an uncoated form, the excipient formulation comprising a release control agent and an ingredient selected from the group consisting of: a lubricating agent, a filling agent and a mixture thereof, the ratio of the release control agent to the ingredient ranging from 0.2 to 170; and (d) a cover layer adhered to the wall, wherein at least one of the container or the cover layer is semi-permeable to said pharmaceutical agent.