Patent ID: 7049068
Filing Date: 2006-05-23
Classification: B82Y,C12Q

Abstract:
1. A microelectronic device useful for the electrochemical detection of a nucleic acid species, said device comprising: a microelectronic substrate having first and second opposing faces; a plurality of conductive oxidation-reduction detection electrodes on said first face; and a plurality of oligonucleotide capture probes immobilized on a non-conductive layer on said first face adjacent said oxidation-reduction electrodes; with each of said plurality of oligonucleotide capture probes positioned adjacent a different oxidation-reduction electrode; and with each of said plurality of oligonucleotide capture probes and said oxidation-reduction detection electrodes electrically connected by an aqueous solution, said aqueous solution having a transition metal complex therein; and wherein said aqueous solution connecting each of said plurality of oligonucleotide capture probes and said oxidation-reduction detection electrodes is the same.