Patent ID: 6204254
Filing Date: 2001-03-20
Classification: A61K,A61L,C07B,C07H

Abstract:
A compound having a formula: ##STR2##whereinA and B are sugars forming a repeating disaccharide unit in which A and B are joined covalently by a glycosidic bond between C-1 of sugar A and C-3 or C-4 of sugar B, and the repeating disaccharide units are joined covalently to form an oligosaccharide by a glycosidic bond between C-1 of sugar B of a first disaccharide unit and C-3 or C-4 of sugar A in a next successive disaccharide unit,B' is a sugar at a non-reducing terminus of said oligosaccharide of ring structure identical to sugar B,A' is an acyclic hexose joined covalently by a glycosidic bond between C-1 of sugar B at a terminus opposite the non-reducing terminus of said oligosaccharide and C-3 or C-4 of sugar A',n is an integer from 2 to 20,L is an aliphatic, acyclic carbon chain which links Y to the 1-amino, 1-amido or 1-imino group attached to C-1 of sugar A', the aliphatic, acyclic carbon chain containing one or more moieties selected from the group consisting of ether, thio ether, and amide;Y is selected from the group consisting of a methylene radical, .beta.-hydroxyethylene radical, carboxyl radical, succinimide .alpha. radical, and a covalent bond; andPR is a prosthetic surface.