Patent ID: 6465482
Filing Date: 2002-10-15
Classification: C07D

Abstract:
A compound of the formula: wherein:R1, R2 and R3 are each, independently, hydrogen, halogen, CF3, alkyl, alkoxy, MeSO2, or any two of R1, R2 and R3 taken together with the ortho and meta carbon atoms of the ring to which they are attached can form a 5-7 membered carbocyclic or heterocyclic ring which includes up to two non-carbon ring atoms each of which independently is either N or O; R4 is hydrogen, halogen, or alkyl; R5 is hydrogen, alkyl, alkylaryl, or aryl; R6 is hydrogen, halogen, CF3, CN, carbamido, or alkoxy; X1, X2 and X3 are each carbon or one of X1, X2 or X3 may be nitrogen; Y is carbon; and Z is carbon or nitrogen; or pharmaceutically acceptable salts thereof.