Patent ID: 6465524
Filing Date: 2002-10-15
Classification: A61K,A61P

Abstract:
A method of treating post-traumatic stress disorder in a mammal, comprising administering to the mammal an effective amount of a compound of the formula: in which A is a moiety of the formula whereinthe dotted line represents optional unsaturation; R1 is hydrogen or alkyl of 1 to 6 carbon atoms; R2 is alkyl of 1 to 6 carbon atoms; R4 is hydrogen, alkyl of 1 to 6 carbon atoms, formyl, or alkanol of 2 to 7 carbon atoms; R5 and R6 are, independently, hydrogen, hydroxyl, alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, alkanoyloxy of 2 to 7 carbon atoms, cyano, nitro, alkylmercapto of 1 to 6 carbon atoms, amino, alkylamino of 1 to 6 carbon atoms, dialkylamino in which each alkyl group is of 1 to 6 carbon atoms, alkanamido of 2 to 7 carbon atoms, halo, trifluoromethyl, or taken together, methylene dioxy; R7 is hydrogen or alkyl of 1 to 6 carbon atoms; and n is 0, 1, 2, 3, or 4; or a pharmaceutically acceptable salt thereof.