Patent ID: 8969051
Filing Date: 2015-03-03
Classification: C12N,C12P,Y02P

Abstract:
1. A process for producing an optically active 2-alkyl-1,1,3-trialkoxycarbonylpropane represented by Formula (2): wherein each of R1, R2 and R3 independently represents a C1-C4 alkyl group, and * represents that the carbon atom is an asymmetrical center, the process comprising a step of asymmetric hydrolysis of an 2-alkyl-1,1,3-trialokoxycarbonylpropane represented by Formula (1): wherein R1, R2 and R3 are as defined above, by using an enzyme capable of selectively hydrolyzing an ester moiety of either one enantiomer of the 2-alkyl- 1,1,3-trialkoxycarbonylpropane represented by Formula (1), or a culture of a microorganism capable of producing the enzyme or a treated object thereof, wherein the enzyme is an esterase or a lipase originated from Arthrobacter strain SC-6-98-28 (FERM BP-3658) or Chromobacterium strain SC-YM-1 (FERM BP-6703).