Patent ID: 8653262
Filing Date: 2014-02-18
Classification: A61P,C07D

Abstract:
1. A compound of general formula (I), wherein A is a group selected from C piperidinyl, optionally substituted by one or more —C morpholinyl, optionally substituted by one or more —C pyrrolidinyl, optionally substituted by one or more —C piperazinyl, optionally substituted by one or more —C azepanyl, optionally substituted by one or more —C L is a linker selected from a single bond, or M, with M being —C D is L′ is a single bond, E is G is a group selected from 4-bromo-phenyl, 3-chloro-phenyl, 4-chloro-phenyl, 3,4-dichloro-phenyl, 3,5-dichloro-phenyl, 2,3-dichloro-phenyl, 2,4-dichloro-phenyl, 2,5-dichloro-phenyl, 3,5-di-trifluoromethyl-phenyl, 3-trifluoromethyl-phenyl, 3-fluoro-5-trifluoromethyl-phenyl, 3-chloro-5-trifluoromethyl-phenyl, 3-chloro-4-trifluoromethyl-phenyl, 3-isopropyl-phenyl, 4-isopropyl-phenyl, 3,5-dimethoxy-phenyl, 3-chloro-4-methoxy-phenyl and 2-methyl-4-chloro-phenyl, optionally in form of their individual optical isomers, mixtures of their individual optical isomers, or racemates, as well as in form of their acid addition salts with pharmacologically acceptable acids.