Patent ID: 6624295
Filing Date: 2003-09-23
Classification: A61K,A61P,C07K

Abstract:
An isolated nucleic acid molecule comprising a nucleotide sequence encoding an antibody or antibody fragment thereof, wherein said antibody or antibody fragment:(a) specifically binds a factor IX/IXa Gla domain; and (b) comprises a heavy chain and a light chain variable region further wherein: (i) the heavy chain variable region comprises a CDR1 which is SEQ ID NO: 10, a CDR2 which is SEQ ID NO: 11 and a CDR3 which is SEQ ID NO: 12; and (ii) the light chain variable region comprises an 1cCDR1 which is SEQ ID NO: 13, an 1cCDR2 which is SEQ ID NO: 14, and an 1cCDR3 which is SEQ ID NO: 15.