Patent ID: 6200977
Filing Date: 2001-03-13
Classification: A61K,A61P,C07D

Abstract:
A compound having the formula: ##STR130##whereinX is --NR.sup.3 R.sup.4 ;Y is --N(R.sup.6)--;R.sup.1 is a member selected from the group consisting of --NO.sub.2, --C(O)R.sup.9, --CO.sub.2 R.sup.10, --C(O)NR.sup.7 R.sup.8, --S(O).sub.m NR.sup.7 R.sup.8, and --CN;R.sup.2 is a member selected from the group consisting of hydrogen alkyl, --O-alkyl, --S-alkyl, halogen and cyano;R.sup.3 and R.sup.4 are taken together with the nitrogen atom to which each is attached to form a 5-membered ring containing from one to three heteroatoms in the ring;R.sup.5 is a member selected from the group consisting of alkyl, aryl and arylalkyl;R.sup.6 is a member selected from the group consisting of hydrogen, alkyl, aryl and arylalkyl; or is combined with R.sup.5 and the nitrogen atom to which R.sup.5 and R.sup.6 are attached to form a 5-, 6-, 7- or 8-membered ring;R.sup.7 and R.sup.8 are members independently selected from the group consisting of hydrogen and alkyl;R.sup.9 and R.sup.10 are members independently selected from the group consisting of hydrogen, alkyl, aryl and arylalkyl;m is an integer of from 1 to 2; andsaid compound having a molecular weight of from about 150 to about 750, with the proviso that --Y--R.sup.5 is other than an imidazole ring.