Patent ID: 9103760
Filing Date: 2015-08-11
Classification: B01L,G01N

Abstract:
1. A microfluidic interrogation apparatus, comprising: indexing structure effective to hold a microfluidic device at an installed position such that an interrogation aperture of said microfluidic device is urged near to a desired location, said microfluidic device being of the type arranged to urge particles of interest through said interrogation aperture in a substantially single-file arrangement; a source of stimulation radiation structured to emit radiation as a beam oriented for propagation of radiation in a particular direction; adjustment means to refine alignment of said interrogation aperture, from an initially installed position, and with respect to said beam, to maximize beam propagation into said interrogation aperture; sensor means disposed to provide steering feedback to said adjustment means; and a first photodetector disposed to detect Stokes-shift emission radiation from a particle disposed inside said interrogation aperture, wherein: