Patent ID: 8486389
Filing Date: 2013-07-16
Classification: A61K,A61P,C12Y

Abstract:
1. A method for reducing an oxalate concentration in a human or animal, comprising, administering to a human or animal an effective amount of freeze-dried viable bacterial cells of Oxalobacter formigenes or oxalate-reducing enzymes, admixed with at least one cryopreservative agent, wherein the amount effective in reducing a portion of the oxalate present from dietary sources or from endogenous sources is from about 10 7 to about 10 12 colony forming units of Oxalobacter formigenes or from about 5 to about 5,000 units of oxalate-reducing enzymes, and wherein the freeze-dried Oxalobacter formigenes cells or oxalate-reducing enzymes are enteric coated for delivery to the small intestine of the human or animal.