Patent ID: 9061029
Filing Date: 2015-06-23
Classification: A61K,A61P,C07D

Abstract:
1. A method of treating a proliferative disorder wherein the proliferative disorder or other pathological condition is selected from melanoma, breast cancer, cancer of the colon, lung cancer, cancer of the prostate or Kaposi's sarcoma, gastrointestinal stromal tumors (GIST), acute myeloid leukemia (AML), leukemia which responds to an inhibition of the Abl tyrosine kinase activity, mesothelioma, systemic mastocytosis, hypereosinophilic syndrome (HES), fibrosis, rheumatoid arthritis, polyarthritis, scleroderma, lupus erythematosus, graft-versus host diseases, neurofibromatosis, pulmonary hypertension, Alzheimer's disease, seminomas and dysgerminomas and psoriasis comprising oral administration of an effective dose of a pyrimidylaminobenzamide of formula (I): wherein (a) Py denotes 3-pyridyl, R R R R R or (b) Py denotes 5-pyrimidyl, R or a pharmaceutically acceptable salt thereof, and, optionally, pharmaceutically acceptable carriers, dispersed in a fruit preparation, to a human patient in need thereof.