Patent ID: 6024965
Filing Date: 2000-02-15
Classification: A61K,A61P,C07K,C12N

Abstract:
An immunogenic composition which consists essentially of:(1) at least one cytotoxic T-cell epitope selected from the group consisting of the cytotoxic T-cell epitope of the Rev protein and the cytotoxic T-cell epitope of the Tat protein effective to generate a specific cytotoxic T-cell response to the Rev and/or Tat proteins of an immunodeficiency virus, or(2) a vector encoding at least one cytotoxic T-cell epitope selected from the group consisting of the cytotoxic T-cell epitope of the Rev protein and the cytotoxic T-cell epitope of the Tat protein effective to generate a specific cytotoxic T-cell response to the Rev and/or Tat proteins of an immunodeficiency virus.