Patent ID: 7893087
Filing Date: 2011-02-22
Classification: A61P,C07D

Abstract:
1. A combination which comprises (a) a compound of formula (I): wherein R n is an integer from 0 to 4; A represents a group selected from —CH m is an integer from 0 to 8, provided that when m is 0, A is not —CH p is an integer from 1 to 2 and the substitution in the azonia bicyclic ring may be in the 2, 3 or 4 position including all possible configurations of the asymmetric carbons; G represents O or S; R wherein q is 1 or 2 and R 11 represents a hydrogen or halogen atom, a hydroxy group, an alkoxy group, a nitro group, a cyano group, —CO 2 R 12 or —NR 12 R 13 , wherein R 12 and R 13 are identical or different and are selected from hydrogen and straight or branched lower alkyl groups, or a straight or branched, substituted or unsubstituted lower alkyl group; R X (b) a second compound which is a β