Patent ID: 6214843
Filing Date: 2001-04-10
Classification: A61K,C07D

Abstract:
A method of treating and/or preventing ischemic intestinal lesions and/or ileus in a patient comprising administering to the patient an ischemic intestinal lesions and/or ileus-therapeutically and/or prophylactically effective amount of a pyrazolopyridine compound of the following general formula: ##STR5##wherein R.sup.1 is lower alkyl, aryl which may have one or more suitable substituent(s), or heterocyclic group;R.sup.2 is a group of the formula: ##STR6##(wherein R.sup.4 is protected amino or hydroxy and R.sup.5 is hydrogen or lower alkyl),cyano,a group of the formula: --A--R.sup.6(wherein R.sup.6 is acyl and A is a lower aliphatic hydrocarbon group which may have one or more suitable substituent(s)),amidated carboxy,unsaturated heterocyclic group which may have one or more suitable substituent(s), amino, orprotected amino; andR.sup.3 is hydrogen, lower alkyl, lower alkoxy, or halogen;or a salt thereof.