Patent ID: 7888470
Filing Date: 2011-02-15
Classification: A23L,A23V,A61K,C07C,C07D,C07F,G01N

Abstract:
1. A heteromeric T1R2/T1R3 receptor that responds to sweet or umami taste compounds comprising, a T1R2 subunit and a T1R3 subunit wherein the T1R2 subunit contains an extracellular region that possesses at least 90% sequence identity to the extracellular region of the human T1R2 polypeptide in SEQ ID NO:16 and a transmembrane and intracellular region that respectively possess at least 90% sequence identity to the transmembrane and intracellular region of the rat T1R2 polypeptide in SEQ ID NO:17 and the T1R3 subunit is a polypeptide that possesses at least 90% sequence identity to the rat T1R3 subunit contained in SEQ ID NO:18 or is a T1R3 polypeptide containing an extracellular region that possesses at least 90% sequence identity to the rat T1R3 extracellular region in SEQ ID NO:18 and containing transmembrane and intracellular regions that respectively possess at least 90% sequence identity to the human transmembrane and intracellular regions in SEQ ID NO:19 or comprises a T1R3 polypeptide that possesses at least 90% sequence identity to the rat T1R3 subunit contained in SEQ ID NO:18.