Patent ID: 7078403
Filing Date: 2006-07-18
Classification: A61P,C07D

Abstract:
1. A compound of formula I or a salt or pharmaceutically acceptable derivative thereof, where: Het is a radical of the formula: wherein each R 1 is independently selected from the group consisting of hydrogen, di(C 1-6 alkylamino, cyano, formyl, C 1-6 alkoxy, hydroxyC 1-4 alkyl, C 1-4 alkoxyC 1-4 alkyl, C 1-6 haloalkoxy, aryloxy, C 1-6 -alkylthio, arylthio, C 1-6 alkylsulphinyl, C 1-6 alkylsulphonyl, arylsulphinyl, arylsulphonyl, —CH═NO-C 1-4 alkyl, C 1-6 alkoxycarbonyl, C 1-6 alkylcarbonyl and aryl; R or R each Y is independently O or S; and each Y′ is O, SO or SO A is O, S, NH, N(C where one or more of the carbon atoms within the radicals (b-1) to (b-4) may be optionally substituted with C 1-6 alkyl or two carbon atoms in the radicals (b-1) to (b-4) may be bridged with a divalent C 2-4 alkyl radical, m and n are each Alk is divalent C W is O, S, OCH Ar is a radical of the formula: X X with the proviso that when Alk is a direct bond and A is O, S, CH