Patent ID: 7211404
Filing Date: 2007-05-01
Classification: A01K,A61K,A61P,C12N,G01N,Y02A

Abstract:
1. A method of selecting for human liver engrafting cells, the method comprising: combining reagents that specifically recognize a marker selected from the group consisting of 5E12; Ep-Cam; CD49f; and E-Cadherin; and a reagent that specifically recognizes MHC class I antigens with a sample of human liver cells; and selecting for cells that are positive for a marker selected from the group consisting of 5E12; Ep-Cam; CD49f; and E-Cadherin; and low to negative for MHC Class I antigens, to provide a selected population of human liver engrafting cells wherein at least 80% of the cells in said population are MHC class I