Patent ID: 8088798
Filing Date: 2012-01-03
Classification: A61P,C07D,C07F

Abstract:
1. A method of treating a disease, comprising: administering to a mammal in need thereof a therapeutically effective amount of a compound of formula I or a stereoisomer or pharmaceutically acceptable salt thereof, wherein the disease is selected from obesity, diabetes, cardiometabolic disorders, and a combination thereof: wherein: X and Y are independently selected from H, halogen, C X′ and Y′ are independently selected from H, halogen, C A is selected from H, C R′ is R″ is selected from H, C Z is selected from H, C Q is selected from N, CH, and CQ′; Q′ is selected from H, CO V is selected from H, C R is independently selected from H, C R m is selected from 0, 1, 2, 3, and 4; n is selected from 1, 2, 3, and 4; and, p is selected from 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, and 12; provided that at least one of the following is satisfied: