Patent ID: 9044212
Filing Date: 2015-06-02
Classification: A61B,A61F,A61M

Abstract:
1. A backflow limiting device for delivery of at least one treating composition to a treatment region of a tissue structure comprising: a multilumen catheter including at least one first lumen having a distal end terminating in a substantially non-expandable, circumferential chamber positioned about the inside of said catheter, wherein at least a portion of said chamber is sized and shaped to provide at least one cryoseal resulting in direct catheter-interstitial tissue interface about a circumference of said catheter at a distance from an injecting site, said cryoseal sized and shaped to seal said catheter directly to said tissue without the need of a pressurized balloon to initiate tissue adherence which is effective to minimize or prevent backflow of at least one treating composition back along a catheter entry track, said lumen in fluid connection with at least one cryogenic source effective for lowering at least a portion of said tissue structure to a temperature at or about the tissue freezing point to form said cryoseal, and at least one second lumen in fluid communication with a treating composition source and having a delivery end adapted for delivery of said at least one treating composition to an interstitial space within a tissue structure, said delivery end positioned a distance from said cryoseal to allow administration of said at least one treating composition to said tissue at a location which is distal from said cryoseal; said multilumen catheter being constructed and arranged for injecting said at least one composition to a treatment region within said tissue structure prior to, subsequent to, or concurrently with formation of said cryoseal; and an outer sheath member having a substantially continuous side wall and a main lumen sized and shaped to be coaxially aligned with said multilumen catheter; whereby said at least one cryoseal formed proximal to said treatment region is effective to minimize or prevent backflow of said treating composition.