Patent ID: 7427610
Filing Date: 2008-09-23
Classification: A61K,A61P,C07J

Abstract:
1. A method of treating a tumor disease which is selected from the group consisting of breast cancer, prostate cancer, colon cancer, non-small-cell-lung cancer and primary dermal microvascular endothelial cell proliferation comprising administering to a subject in need thereof an effective amount of a compound of formula I wherein R R n=1,2,3,4,5 or 6, m>1, m+o=2n+1, R R R R R R if R X is fluorine, or hydroxyl, Y is hydrogen or fluorine, if X is hydroxyl, Y is hydrogen, or X and Y together can be oxygen, R wherein in the B- and D-ring of the compound of formula I, the dotted lines can be up to two double bonds, provided that when a double bond is present in the D ring, only R