Patent ID: 8981114
Filing Date: 2015-03-17
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A compound having a structure according to Formula (I), wherein: R a substituted or unsubstituted alkyl; or a substituted or unsubstituted aryl or heteroaryl; in either S or R configuration; R (a) a substituted or unsubstituted alkyl; (b) a substituted or unsubstituted phenyl; (c) a 5- or 6-membered, optionally substituted, saturated or unsaturated heterocyclic group having from one to three heteroatoms selected from nitrogen, oxygen and sulfur; (d) a saturated or unsaturated fused ring carbocyclic group, optionally substituted, having from 8 to 10 ring atoms; (e) a saturated or unsaturated fused ring heterocyclic group, optionally substituted, having from 8 to 10 ring atoms including one to three heteroatoms selected from nitrogen, oxygen and sulfur; X is a hydrogen atom, carbonyl, thiocarbonyl or imine, If X is a hydrogen atom then R If X is not hydrogen then R (a) a substituted or unsubstituted linear, branched or cyclic alkyl which additionally can be connected to an aromatic or heterocyclic moiety, (b) a substituted or unsubstituted phenyl, (c) a 5- or 6-membered, saturated or unsaturated heterocyclic group, optionally substituted, having from one to three heteroatoms selected from nitrogen, oxygen and sulfur; (d) NR'(CH R′ is hydrogen or alkyl, n is 0-3, R″ is unsubstituted or substituted alkyl, cycloalkyl, phenyl, benzyl, a 5- or 6-membered, optionally substituted saturated or unsaturated heterocyclic group having from one to three heteroatoms selected from nitrogen, oxygen and sulfur, and R′ and R″ can be connected or not, (e) O(CH or a tautomer, pharmaceutically acceptable salt, hydrate, or solvate thereof.