Patent ID: 8609892
Filing Date: 2013-12-17
Classification: A61P,C07C,C07D

Abstract:
1. A compound structurally represented by Formula I or a pharmaceutically acceptable salt thereof wherein: Y is —O— or —S—; Q, D, X, and T independently represent carbon (substituted with hydrogen or the optional substituents as indicated herein), or nitrogen (optionally substituted with oxygen), provided that no more than two of Q, D, X, and T are nitrogen; R1 is —H, —OH, or -halogen; R2 is —H or —(C R3 and R4 are independently R5 is selected from the group consisting of R6 and R7 are independently at each occurrence selected from the group consisting of R8 and R9 are independently at each occurrence selected from the group consisting of R10 is selected from the group consisting of R11 is independently at each occurrence selected from the group consisting of wherein the zig-zag mark shows the point of attachment to the parent molecule, wherein A, G, and E independently represent carbon (substituted with hydrogen or the optional substituents as indicated herein) or nitrogen, provided that no more than two of A, G, and E are nitrogen; provided however that wherein A is nitrogen, then R8, R9, and R14 are not attached to A, and provided that wherein G is nitrogen, then R8, R9, and R14 are not attached to G, and provided that wherein E is nitrogen, then R8, R9, and R14 are not attached to E, wherein the zig-zag mark shows the point of attachment to the parent molecule, wherein m is an integer of 0, 1, 2, or 3, and when m is 0 then (CH 2 ) m is a bond, and wherein the zig-zag mark shows the point of attachment to the parent molecule, provided however that wherein D is nitrogen, then R11 is not attached to D, and provided that wherein T is nitrogen, then R11 is not attached to T, and provided that wherein Q is nitrogen, then R11 is not attached to Q, and provided that wherein X is nitrogen, then R11 is not attached to X; R12 is independently at each occurrence selected from the group consisting of R13 is independently at each occurrence selected from the group consisting of R14 is independently at each occurrence