Patent ID: 6410570
Filing Date: 2002-06-25
Classification: A61K,Y10S

Abstract:
A method of inactivating a virus containing a metal-protein complex comprising the step of exposing said virus to a metal chelating agent so that the metal chelating agent chelates said metal within said metal-protein complex so as to denature said protein and inactivate the virus, wherein said metal chelating agent is represented by the following structure: or a pharmacologically acceptable salt thereof,wherein R1, R2, R3 and R4 are selected from the group consisting of a peptide of sixteen amino acids, carboxyl group, methyl group, ethyl group, propyl group, isopropyl group, butyl group, isobutyl group, secondary butyl group, tertiary butyl group, pentyl group, isopentyl group, neopentyl group, fluorine, chlorine, bromine, iodine, and hydrogen; wherein said metal chelating agent is not a zinc-picolinate complex prior to exposure to said virus.