Patent ID: 6719990
Filing Date: 2004-04-13
Classification: A61K

Abstract:
A composition of matter, comprising:somatotropin and a constituent that enhances bioavailability of the somatotropin in an animal to which the composition of matter has been administered parenterally; wherein the bioavailability enhancing constituent is selected from the group consisting of one or a mixture of both of the following: a) one or more non-reducing carbohydrate(s) and b) one or more oxo-acid salt(s); wherein the somatotropin and the bioavailability enhancing constituent are suspended in a substantially non-aqueous hydrophobic carrier, wherein the somatotropin is present at from about 10 to about 50% by weight of the composition, wherein the bioavailability enhancing constituent is present at from about 1% to about 20% by weight of the composition, and wherein the composition is fluidly injectable at 25Â° C.