Patent ID: 6794545
Filing Date: 2004-09-21
Classification: A61K,A61P,C07C,C07D,C07K

Abstract:
A conformationally restricted polyamine analog of the formula:Eâ€”NHâ€”Bâ€”Aâ€”Bâ€”NHâ€”Bâ€”Aâ€”Bâ€”NHâ€”Bâ€”Aâ€”Bâ€”NHâ€”Bâ€”Aâ€”Bâ€”NHâ€”E wherein each A is independently selected from the group consisting of: a single bond, C1-C6 alkyl, and C2-C6 alkenyl; each B is independently selected from the group consisting of: C1-C6 alkyl and C2-C6 alkenyl; and each E is independently selected from the group consisting of H, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C6 cycloalkyl, C3-C6 cycloaryl, and C3-C6 cycloalkenyl; with the proviso that at least one A moiety is selected from the group consisting of C2-C6 alkenyl; and any salt or stereoisomer thereof.