Patent ID: 8168232
Filing Date: 2012-05-01
Classification: A61K,A61P,Y10S

Abstract:
1. A method for controlling, treating and/or decreasing progression of cancer, malignancies, and/or tumor angiogenesis in a human subject, the method comprising: administering a low dose of a nitric oxide mimetic to the human subject, to control, treat, and/or decrease progression of cancer, malignancies, and/or tumor angiogenesis; wherein the nitric oxide mimetic is an organic nitrate; wherein the low dose is 3 to 10,000 fold lower than a dose of nitric oxide mimetic that produces vasodilation in the human subject; wherein the low dose of nitric oxide mimetic does not induce substantial tolerance in the human subject; and wherein the low dose is sustained for the duration of controlling, treating and/or decreasing progression of cancer, malignancies, and/or tumor angiogenesis in the human subject.