Patent ID: 8673824
Filing Date: 2014-03-18
Classification: C07H,C12N,C12Q,C40B,G01N

Abstract:
1. A chemical library comprising stable combination reaction products between a first number of chemical compounds of a sub-library A with a sub-library B of chemical compounds, wherein the compounds of the sub-library A comprise: (i) a chemical moiety (p) capable of performing a binding interaction with a single target molecule, and (ii) an oligonucleotide (b) or functional analogue thereof, which comprises a variable, unique distinctive sequence tag (b2) coding for the identification of the chemical moiety (p) of its compound and a common self-assembly sequence (b1) capable of performing a combination reaction and of building a stable combination reaction product with a common self-assembly sequence (b1′) of a plurality of chemical compounds of the sub-library B, wherein the sub-library B comprises a second number of chemical compounds each comprising: (i) a chemical moiety (q) capable of performing a binding interaction with a single target molecule, and (ii) an oligonucleotide (b′) or functional analogue thereof, which comprises a variable, unique distinctive sequence tag (b2′) coding for the identification of the chemical moiety (q) of its compound, and the common self-assembly sequence (b 1′), wherein the chemical moieties (p,q) are peptides or globular proteins.