Patent ID: 7378518
Filing Date: 2008-05-27
Classification: A61P,C07D,Y10S

Abstract:
1. A compound represented by the structural formula (I): or pharmaceutically acceptable isomers, salts, solvates or esters of the compound of Formula (I), wherein in Formula (I) above: X, Y and Z can be the same or different and each is independently selected from the group consisting of —CH Q Q Q Q wherein optionally one or more carbon atoms of the —(C G is selected from the group consisting of a sugar residue, disugar residue, trisugar residue, tetrasugar residue, sugar acid, and amino sugar wherein optionally the sugar residue, disugar residue, trisugar residue, tetrasugar residue, sugar acid, or amino sugar of G is substituted with -L-M; L is selected from the group consisting of  wherein Me is methyl; M is selected from the group of moieties consisting of  pharmaceutically acceptable salts of the moieties (M1) to (M9) and free acids of the moieties (M1) to (M9); R R each R each R q is 0 or 1; r is 0 or 1; m, n and p are independently selected from 0, 1, 2, 3 or 4; provided that at least one of q and r is 1, and the sum of m, n, p, q and r is 1, 2, 3, 4, 5 or 6; and provided that when p is 0 and r is 1, the sum of m, q and n is 1, 2, 3, 4 or 5; x1 is 1 to 10; x2 is 1 to 10; x3 is 1 to 10; x4 is 1 to 10; x5 is 1 to 10; x6 is 1 to 10; and x7 is 1 to 10; x8 is 1 to 10; x9 is 1 to 10; x10 is 1 to 10; and x11 is 1 to 10; with the proviso that at least one of Q wherein each of the above alkyl, alkenyl, alkynyl, alkylene, alkoxyalkoxy, alkoxyalkoxyalkoxy alkoxycarbonylalkoxy, alkoxyarylalkoxy, alkoxyiminoalkyl, alkyldioyl, allyloxy, aryl, arylalkyl, aryloxy, arylalkoxy, aroyl, aroyloxy, aroylaroyloxy, arlalkoxycarbonyl, benzoylbenzoyloxy, heteroaryl, heteroarylalkyl, heteroarylalkoxy, dioxolanyl, heterocyclyl, heterocyclylalkyl, heterocyclylcarbonyl, or heterocyclylcarbonylalkoxy groups, when present, is independently substituted or unsubstituted.