Patent ID: 8071300
Filing Date: 2011-12-06
Classification: C12N,C12P,C12Q,G01N

Abstract:
1. A method of determining the ability of a patient to generate the phosphoric ester of the compound represented by general formula (I), which comprises the following steps (1) and (2): (1) measuring the expression level of a polypeptide in a blood sample collected from a subject, wherein the polypeptide is selected from the group consisting of: (2) comparing the expression level of the polypeptide measured in (1) above with the expression level of said polypeptide in a sample that has been confirmed as having the ability to phosphorylate in vivo the compound represented by general formula (I), so as to examine the ability of the subject to phosphorylate the compound represented by general formula (I), wherein the compound represented by general formula (I) has the formula: wherein each of R Y represents a single bond, an oxygen atom, a sulfur atom or a carbonyl group; Z represents a single bond or a C1-C8 alkylene group; and n is 2 or 3.