Patent ID: 7745146
Filing Date: 2010-06-29
Classification: G01N

Abstract:
1. A method of detecting an autoantibody in a subject suspected of having an acute atherosclerotic syndrome comprising the steps of: a) obtaining a serum or plasma sample from the subject, wherein the serum or plasma sample may contain IgA autoantibodies specific for β b) contacting the serum or plasma sample with a polypeptide consisting of β c) detecting the IgA antibodies autoantibodies in the complex to establish a level of IgA autoantibodies in the serum or plasma; and d) comparing the level of IgA autoantibodies in the complex to a control level of IgA autoantibodies in serum or plasma from healthy control individuals; wherein if the level of IgA autoantibodies in the complex is greater than the control level, this indicates that the subject may have an acute atherosclerotic syndrome.