Patent ID: 7495096
Filing Date: 2009-02-24
Classification: A61P,C07D

Abstract:
1. A process for producing a compound or reaction product of the following formula (I) comprising the steps of: converting a compound of formula (II) with 2-pyrrolidone in an amount of 1.5 to 5 mol relative to the amount of compound (II) to form a reaction mixture; heating said reaction mixture to an initial temperature of 70° C. to 130° C.; maintaining said initial temperature for a period of 0.5 to 2 hours; subsequently heating said reaction mixture to a subsequent temperature of 140° C. to 200° C.; maintaining said subsequent temperature for a period of 1 to 8 hours; and crystallizing said reaction product (I) to isolate said reaction product (I) directly from said reaction mixture.