Patent ID: 6716627
Filing Date: 2004-04-06
Classification: A61K,C12N,Y02P

Abstract:
A compound 8 to 50 nucleobases in length targeted to nucleobases 187 through 246, nucleobases 344 through 363, nucleobases 694 through 723, nucleobases 829 through 854, nucleobases 860 through 879, nucleobases 940 through 959, nucleobases 997 through 1016, nucleobases 1037 through 1084, nucleobases 1091 through 1134, nucleobases 1168 through 1187, nucleobases 1251 through 1287, nucleobases 1371 through 1390, nucleobases 1397 through 1431, nucleobases 1499 through 1518, nucleobases 1540 through 1559, or nucleobases 1582 through 1601 of a coding region, nucleobases 1586 through 1613 of a stop codon region, or nucleobases 1606 through 1654 of a 3â€²-untranslated region of a nucleic acid molecule encoding mucin 1, transmembrane of SEQ ID NO: 3, wherein said compound specifically hybridizes with one of said regions and inhibits the expression of mucin 1, transmembrane.