Patent ID: 8962236
Filing Date: 2015-02-24
Classification: A61P,C07K,C12N,C12Q,C12Y,G01N

Abstract:
1. A method for assessing risk of cancer-related death among gastric cancer patients, comprising the steps of: (a) treating gastric tissue samples taken from the patients with a bisulfite; (b) performing a methylation-specific polymerase chain reaction to amplify a genomic sequence comprising SEQ ID NO:1 using an oligonucleotide primer consisting of the nucleotide sequence of SEQ ID NO: 10, 11, 12, 13, 14 or 15, and determining whether in each sample genomic sequence of SEQ ID NO:1 is methylated or unmethylated; and (c) assigning a higher risk of cancer-related death to a patient whose sample contains methylated genomic sequence of SEQ ID NO:1 and assigning a lower risk of cancer-related death to another patient whose sample contains unmethylated genomic sequence of SEQ ID NO:1.