Patent ID: 7208296
Filing Date: 2007-04-24
Classification: C12N,C12P,C12R

Abstract:
1. A method for producing L-glutamic acid by fermentation, which comprises culturing an isolated microorganism in a liquid medium of which pH is adjusted to the pH at which L-glutamic acid is precipitated, to produce and accumulate L-glutamic acid and precipitate L-glutamic acid in the medium, wherein said microorganism can metabolize a carbon source at a specific pH in a liquid medium containing the carbon source and L-glutamic acid at a saturation concentration, and has the ability to accumulate L-glutamic acid in an amount exceeding the amount corresponding to the saturation concentration in the liquid medium at the pH, wherein said microorganism is wherein said microorganism has at least one of the following characteristics: (a) the microorganism has increased activity, as compared to a corresponding wild-type microorganism, of an enzyme that catalyzes a reaction for biosynthesis of L-glutamic acid; and (b) the microorganism has decreased activity, as compared to a corresponding wild-type microorganism, or deficient activity of an enzyme that catalyzes a reaction of a pathway branching from a biosynthetic pathway of L-glutamic acid and producing a compound other than L-glutamic acid.