Patent ID: 8440698
Filing Date: 2013-05-14
Classification: A61P,C07D

Abstract:
1. A method of treating an immunosuppressant disorder associated with the sphingosine-1-phosphate receptor modulation, wherein the immunosuppressant disorder is selected from: rheumatoid arthritis, psoriasis, atherosclerosis, autoimmune uveitis, dry eye, inflammatory bowel diseases, atopic allergy, atopic dermatitis, contact dermatitis, multiple sclerosis, Sjogren's syndrome and organ transplant resection, in a mammal in need thereof, which comprises administering to a mammal in need thereof, a pharmaceutical composition comprising a therapeutically effective amount of at least one compound represented by Formula I or a pharmaceutically acceptable salt thereof: wherein: R is H, C R R R R R a is 0, 1, 2 or 3; b is 0, 1, 2 or 3; c is 0, 1, 2 or 3; R R R R R R R R R R R R R R R R R R R R