Patent ID: 8435781
Filing Date: 2013-05-07
Classification: C12M

Abstract:
1. A radial flow type bioreactor comprising, within a tubular reactor main body ( 6 ), a culturing space housing a culture medium-recovering porous tube ( 5 ), a spacer ( 4 ), and a porous sheet-form material ( 3 ) provided between the spacers, wherein the reactor is formed so that a culture medium supplied from at least one culture medium inlet port ( 1 ) formed in the reactor main body ( 6 ) passes through the culturing space and the culture medium-recovering porous tube ( 5 ) and flows out from a culture medium outlet port ( 2 ) connecting with one end of the porous tube ( 5 ), the porous tube ( 5 ) and the spacer ( 4 ) allowing cells to pass through, and the porous sheet-form material ( 3 ) having its surface, which is hydrophilized with a polyamino acid/urethane copolymer so that the porous sheet-form material ( 3 ) has thereon the polyamino acid/urethane copolymer, covered with a thermosensitive polymer layer, wherein the culture medium-recovering porous tube ( the porous sheet-form material ( the spacer (