Patent ID: 8393556
Filing Date: 2013-03-12
Classification: A61K,A61P,A61Q,B82Y,C07D

Abstract:
1. A method of preparing a composition, comprising a micronised insoluble organic UV absorber with a mean particle size <0.1 μ, which method comprises grinding the insoluble organic UV absorber, in coarse particle form, in a grinding apparatus comprising yttrium-stabilized zirconium oxide grinding beads, in the presence of alkyl polyglucoside having the formula C n H 2n+1 O(C 6 H 10 O 5 ) x H, in which n is an integer ranging from 8 to 16 and x is the mean polymerisation level of the glucoside moiety (C 6 H 10 O 5 ) and ranges from 1.4 to 1.6, or an ester thereof and in the presence of an antifoam agent as dispersing agent auxiliary.