Patent ID: 6436954
Filing Date: 2002-08-20
Classification: A61P,C07D

Abstract:
A compound of the formula: wherein n=1 to 4, and each R1 independently may be hydrogen, halo, or optionally substituted alkyl or cycloalkyl, aryl, arylalkyl, haloalkyl, haloalkoxy, hydroxy, alkoxy, trifluoromethyl, cyano, carboalkoxy, alkanoyl, aroyl, or alkylsulfonyl; wherein R2=NR6R7, alkylaryl, and R6 and R7 may each independently be hydrogen, optionally substituted alkyl or cycloalkyl, aryl, arylalkyl, alkylaryl, aroyl, alkanoyl, alkylaroyl, or arylalkanoyl, or NR6R7 may be azetidino, pyrrolidino, or piperidino, wherein p=1 to 6, and R3 is hydrogen, hydroxy, alkoxy, halo, optionally substituted alkyl or cycloalkyl, aryl, arylalkyl, alkylaryl, haloalkyl, haloalkoxy; wherein R4 is hydrogen, optionally substituted alkyl or cycloalkyl, aryl, arylalkyl, alkylaryl, haloalkyl, or haloalkoxy; and wherein m=2; with the proviso that the compound is not 11O-acetyl-7,8-dimethoxy-1,3,4,6,11,11a-hexahydro-2H-benzo[b]quinolizin-11-ol.