Patent ID: 9018260
Filing Date: 2015-04-28
Classification: A61K,A61P,C07C

Abstract:
1. A compound selected from the group consisting of: 1) N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, 2) N-[(1S)-2,2,4,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, 3) (+)-N-(2,2,4,6,7-pentafluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, 4) N-[(1S*)-5-cyano-2,2-difluoro-7-methyl-2,3-dihydro-1H-inden-1-yl]sulfamide, 5) (−)-N-(7-chloro-2,2,5-trifluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, 6) (−)-N-(7-chloro-2,2,4-trifluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, 7) (−)-N-(7-chloro-2,2-difluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, 8) (−)-N-(7-chloro-2,2,6-trifluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, 9) (+)-N-(5-chloro-2,2,7-trifluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, 10) N-[(1S)-2,2-difluoro-7-methyl-2,3-dihydro-1H-inden-1-yl]sulfamide, 11) N-[(1S)-2,2,5-trifluoro-7-methyl-2,3-dihydro-1H-inden-1-yl]sulfamide, 12) N-[(1S*)-2,2,4-trifluoro-7-methyl-2,3-dihydro-1H-inden-1-yl]sulfamide, 13) N-[(1S*)-7-(difluoromethyl)-2,2-difluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, 14) N-[(1R*,2R*)-2,4,7-trifluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, 15) (−)-N-[(1R*,2R*)-7-chloro-2,4-difluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, 16) (+)-N-[(1R*,2R*)-7-chloro-2,4-difluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, 17) (−)-N-[(1R*,2R*)-7-chloro-2,5-difluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, 18) (+)-N-[(1R*,2R*)-4-chloro-7-fluoro-2-methoxy-2,3-dihydro-1H-inden-1-yl]sulfamide, 19) (+)-N-(7-chloro-4-fluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, 20) (±)-N-(5-fluoro-7-methyl-2,3-dihydro-1H-inden-1-yl)sulfamide, 21) (−)-N-(4-fluoro-7-methyl-2,3-dihydro-1H-inden-1-yl)sulfamide, 22) (+)-N-(4-fluoro-7-methyl-2,3-dihydro-1H-inden-1-yl)sulfamide, 23) (+)-N-(7-methyl-2,3-dihydro-1H-inden-1-yl)sulfamide, 24) (±)-N-(5-chloro-7-methyl-2,3-dihydro-1H-inden-1-yl)sulfamide, 25) (−)-N-(4-chloro-7-fluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, 26) (+)-N-(7-chloro-5-cyano-2,3-dihydro-1H-inden-1-yl)sulfamide, 27) (−)-N-(7-chloro-5-cyano-2,3-dihydro-1H-inden-1-yl)sulfamide, 28) (−)-N-(5-chloro-7-fluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, 29) N-[(1S)-4,7-difluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, 30) (+)-N-(7-chloro-2,3-dihydro-1H-inden-1-yl)sulfamide, 31) (+)-N-(5-cyano-7-methyl-2,3-dihydro-1H-inden-1-yl)sulfamide, 32) (−)-N-(5-cyano-7-methyl-2,3-dihydro-1H-inden-1-yl)sulfamide, 33) N-[(1S)-7-chloro-5-fluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, and 34) (−)-N-(4,6,7-trifluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, or a pharmaceutically acceptable salt thereof.