Patent ID: 6329420
Filing Date: 2001-12-11
Classification: C07C,C07D,C07K

Abstract:
A compound of the formula ##STR18##whereinX is S and forms a saturated or unsaturated heterocyclic ring;R is a saturated or unsaturated (C.sub.7 -C.sub.15) hydrocarbon chain;R.sup.1 and R.sup.2 are independently H, (C.sub.1 -C.sub.6)alkyl, (C.sub.1 -C.sub.6)alkenyl, C.sub.1 -C.sub.6)alkynyl, (C.sub.3 -C.sub.7)cycloalkyl, aryl, or heteroaryl;Y.sup.1 and Y.sup.2 are OH;m is 0 to 6;each S is independently OH, SH, CO.sub.2 H, halogen, CN, acyl, thioacyl, ester, thioester, alkoxy, aryloxy, alkylthio, arylthio, alkyl, alkenyl, alkynyl, (C.sub.3 -C.sub.7)cycloalkyl, aryl, heteroaryl, C(.dbd.O)NR.sup.a R.sup.b, or NR.sup.a R.sup.b ; taken together, two of S can form a ring or any two adjacent carbons can form a double bond;where R.sup.a and R.sup.b are each independently hydrogen, acyl, alkyl, (C.sub.3 -C.sub.7)cycloalkyl, aryl, or heteroaryl; or R.sup.a and R.sup.b together with the nitrogen to which they are attached form a ring selected from the group consisting of pyrrolidino, piperidino, morpholino, and thiomorpholino; andwherein R, R.sup.1, R.sup.2, R.sup.a, and R.sup.b are independently unsubstituted or substituted with OH, SH, CO.sub.2 H, halogen, CN, acyl, thioacyl, ester, thioester, (C.sub.1 -C.sub.6)alkoxy, (C.sub.1 -C.sub.6)aryloxy, (C.sub.1 -C.sub.6)alkylthio, (C.sub.1 -C.sub.6)arylthio, (C.sub.1 -C.sub.6)alkyl, (C.sub.1 -C.sub.6)alkenyl, (C.sub.1 -C.sub.6)alkynyl, (C.sub.3 -C.sub.7)cycloalkyl, (C.sub.6 -C.sub.10)aryl, or (C.sub.6 -C.sub.10)heteroaryl.