Patent ID: 8299256
Filing Date: 2012-10-30
Classification: A61P,C07D

Abstract:
1. A compound of formula (I), the N-oxide forms, the pharmaceutically acceptable addition salts and the stereo-chemically isomeric forms thereof, wherein m is 0, 1 or 2 and when m is 0 then a direct bond is intended; n is 0, 1, 2, 3 or 4 and when n is 0 then a direct bond is intended; X is a direct bond, CR R two carbon atoms on aryl or Het can be bridged thereby forming a bi- or tricyclic moiety with a bivalent radical selected from each aryl, Het, bridged aryl or bridged Het can be substituted with one, two, three, four or five substituents each independently selected from hydrogen, halo, cyano, nitro, hydroxycarbonyl, C R R R each R each R each R