Patent ID: 6153646
Filing Date: 2000-11-28
Classification: A61P,C07F

Abstract:
A compound of formula (I) or (II): ##STR7## wherein: Y--Y is an amine bidentate ligand of the formula:NH.sub.2 --R.sub.1 NH.sub.2 in which R.sub.1 is a C.sub.2 -C.sub.6 linear or branched alkylene group or an o-phenylene group; oror a group of the formula: ##STR8## wherein n=2, 3, 4 or 5; m=0 or 1 and 1=0 or 1; A.sub.1 and A.sub.2 represent either two identical ammine monodentate ligands, n-isopropylamine or (C.sub.3 -C.sub.7) cycloalkylamine or they are bonded together thereby forming an amine bidentate ligand of the formula:NH.sub.2 --R.sub.1 --NH.sub.2 in which R.sub.1 is a C.sub.2 -C.sub.6 linear or branched alkylene group or an o-phenylene group;or a group of the formula: ##STR9## wherein n=2, 3, 4or 5; m=0 or 1 and 1=0 or 1; X represents a bridging ligand linking the two platinum atoms selected from the group consisting of Cl, Br, F and I; the dissociable Ld group represents:either two monodentate B ligands selected from the group consisting of NO.sub.3.sup.-, gluconate and glucuronate; orthe bidentate B--B ligand selected from the group consisting of: ##STR10## wherein R is hydrogen, methyl, ethyl, phenyl or benzyl; and Hal is a halogen atom selected from the group consisting of Cl, Br, F and I.