Patent ID: 8865420
Filing Date: 2014-10-21
Classification: C12Q,G01N,Y10S,Y10T

Abstract:
1. A method of diagnosing, prognosing or determining progression of a disease in a patient, said method comprising: (a) contacting a cell population from said patient with a potentiator; (b) determining the activation states of a plurality of potentiated signaling nodes in single cells from said potentiator contacted cell population, wherein each of said plurality of signaling nodes is different from the other signaling nodes and comprises a first activation state and a second activation state, wherein said determining step comprises: (c) creating a response panel of said potential signaling nodes of said single cells comprising said determined activation states; (d) comparing the response panel in step c to a response panel of signaling nodes in cells for a known disease; and (e) diagnosing, prognosing or determining progression of said disease in said patient based on said comparison.