Patent ID: 6201014
Filing Date: 2001-03-13
Classification: A61K,A61P

Abstract:
A pharmaceutical oral delivery composition for use in the treatment of irritable bowel syndrome, diarrhoea constipation, abdominal pain and/or bloating or abdominal distension in a mammal, said composition being in dosage form as a capsule, a gel, a powder, spheroids or granules and comprising:(i) capsaicin or resiniferatoxin, pharmaceutically acceptable salts, analogues and/or derivatives thereof (component (a)); and(ii) a pharmaceutically acceptable vehicle (component (b)),wherein the composition is in unit dosage form as an osmotic delivery device or is enterically coated to provide release of component (a) in the gastrointestinal tract between the stomach and the rectum of the mammal and component (b) is selected to enable component (a) to be released in the gastrointestinal tract between the stomach and the rectum of the mammal.