Patent ID: 7312190
Filing Date: 2007-12-25
Classification: A61K,A61P,C07K

Abstract:
1. The pharmaceutical composition comprising an ApoA-I agonist and a pharmaceutically acceptable carrier, excipient or diluent; wherein the ApoA-I agonist is in the form of an ApoA-I agonist-lipid complex, said complex comprising the ApoA-I agonist and a lipid; wherein the ApoA-I agonist comprises: a 22 to 29-residue peptide or peptide analogue which forms an amphipathic α-helix in the presence of lipids and which comprises formula (I): or a pharmaceutically acceptable salt thereof, wherein: a N-terminally blocked form, a C-terminally blocked form, or an N- and C-terminally blocked form of formula (I).