Patent ID: 6280936
Filing Date: 2001-08-28
Classification: A61K,C12N,C12Y

Abstract:
A nucleic acid molecule in a purified form with an endonuclease activity, comprising ribonucleotides and having the formula I: ##STR6##wherein, N is independently a nucleotide or a non-nucleotide linker, which may be same or different; M and Q are independently oligonucleotides of length sufficient to stably interact with a target nucleic acid molecule; o and n are integers greater than or equal to 1, wherein if (N).sub.o and (N).sub.n are nucleotides, (N)o and (N)n are optionally able to interact by hydrogen bond interaction; L is a linker which may be present or absent, but when present, is a nucleotide and/or a non-nucleotide linker, which may be a single-stranded and/or double-stranded region; represents a chemical linkage; U3, C4 and N7 indicate the relative position of each said nucleotide in the nucleic acid molecule, and A, C, U and G represent adenosine, cytidine, uridine and guanosine nucleotides, respectively.