Patent ID: 8173387
Filing Date: 2012-05-08
Classification: C12Q

Abstract:
1. A method of assaying whether a chemical is present in a test specimen or not, comprising culturing a first sample of a gene-disrupted strain of a yeast in the presence of the test specimen, culturing a second sample of the gene-disrupted strain of the yeast in the absence of the test specimen; and comparing cell response of the first sample with cell response of the second sample such that predetermined differences in cell response between the first sample and the second sample confirms presence of the chemical in the test specimen, wherein the disrupted gene is classified into: unclassified YBL056W; and/or an unclassified protein selected from the group: YDR149C, YLR285W, YLR311C, YOR331C, YPR123C, YDR525W-A, YDR539W, YDR540C, YGL246C, YJL204C, YLR282C, YLR287C, YLR290C, YJL188C, YJL192C, YJL211C, YKL037W, YLR283W, YLR312C, YLR315W, YLR320 W or YPL030W.