Patent ID: 9068229
Filing Date: 2015-06-30
Classification: A61P,C12Q

Abstract:
1. A method of determining the identity of the alleles of fewer than 1,000 single nucleotide polymorphisms (SNPs) in a woman subject selected from the group of subjects consisting of women in need of screening for breast cancer susceptibility to produce a polymorphic profile of the selected woman subject in need of breast cancer screening, comprising (i) obtaining a biological sample comprising a genome from the selected woman subject in need of breast cancer screening; (ii) selecting for allelic identity analysis at least a SNP located at rs2981582 within the nucleotide sequence of an intron of a Fibroblast Growth Factor Receptor 2 (FGFR2) gene, and a SNP located at rs13281615 within the genome of the selected woman subject in need of breast cancer screening; (iii) assaying, with a probe or a primer, whether (iv) producing the polymorphic profile of the selected woman subject in need of breast cancer screening based on the identity of the alleles assayed in step (iii), wherein fewer than 1,000 SNPs are selected for allelic identity analysis in step (ii) and the same fewer than 1,000 SNPs are assayed in step (iii).