Patent ID: 7919115
Filing Date: 2011-04-05
Classification: A61K,A61P

Abstract:
1. An ODT consisting essentially of: lamotrigine microcapsules comprising 25 or 200 mg of lamotrigine crystals having an average particle size of about 1-50 μm, coated with a taste-masking layer consisting of ethylcellulose, wherein the average coating weight of said microcapsules is about 15% of the total weight of the microcapsules; and rapidly dispersing granules comprising a granulate of crospovidone and mannitol in a ratio ranging from about 90/10 to about 99/1, wherein the rapidly dispersing granules are about 60% to 70% of the total weight of the ODT; and an additional disintegrant comprising crospovidone; wherein after a single oral administration said ODT provides; if the total amount of lamotrigine in the ODT is 25 mg, or if the total amount of lamotrigine in the ODT is 200 mg.