Patent ID: 7531560
Filing Date: 2009-05-12
Classification: C07D

Abstract:
1. A compound of the formula (I) wherein: Ar i) a carbocycle independently substituted by one or more of R wherein one of E or F is nitrogen and the other is carbon, R 1 is covalently attached to either E or F, and when nitrogen is N—R 1 the double bond between E and F is not present; wherein c is a benzo ring fused to ring d which is a 5-7 membered heterocyclic ring optionally substituted by an oxo (═O) group and one to two R groups each independently being H or C1-3 alkyl; (iv) a 5 membered nitrogen containing heteroaryl or heterocyclic ring optionally substituted by R R or R R each R each R D, A and B in of the formula (I) is chosen from: wherein the hydrogen atom is optionally replaced by R Q is —C(O)—R Het is a heterocyclic or heteroaryl ring wherein Het is optionally substituted by one to three R m is 0,1 or 2; J is chosen from C1-10 alkyl and C3-7cycloalkyl each optionally substituted by R R R R wherein n is 1-5; R and X is O or S or a pharmaceutically acceptable salt thereof.