Patent ID: 9180072
Filing Date: 2015-11-10
Classification: A61K

Abstract:
1. A non-obturation, regenerative endodontic treatment technique for a permanent mature tooth, involving regenerative potential of stem cells and signaling molecules locally available in a periapical region of the tooth, wherein said stem cells are stimulated to induce healing and deposition of a mineralized barrier (biological seal) at a root apex of the tooth, thus eliminating a need for a root canal obturation, comprising the steps of: a. widening of apical foramina of the permanent mature tooth's root canals with files larger than an initial apical file (IAF) at working length and irrigating with NaOCl after achieving infection control as evident from a clinically symptom-free tooth with dry canals, healed swelling or sinuses; b. introducing or pushing a sterile reamer of size 30 or less to 2-3 mm past said tooth's apical foramina into said tooth's periapical regions and then withdrawing said reamer; c. leaving the root canals without filling thus eliminating an obturation step; d. introducing calcium sulfate-based cement in an access cavity to cover pulpal floor of the tooth and condensing said calcium-sulfate based cement, with a hand plugger, into a cervical ⅓ of said tooth's root canals for sealing; and e. restoring the access cavity with an appropriate permanent restoration to prevent leakage and re-infection of said root canals.