Patent ID: 7795245
Filing Date: 2010-09-14
Classification: A61P,C07D

Abstract:
1. A compound selected from the group consisting of: wherein: R wherein R R R R wherein each R wherein each R R R wherein each R wherein each R R R R wherein cycloalkyl, 5- to 6-membered heterocycloalkyl, bicycloalkyl, heterobicycloalkyl, spiroalkyl, spiroheteroalkyl, aryl, 5- to 6-membered heteroaryl, cycloalkyl fused aryl, 5- to 6-membered heterocycloalkyl fused aryl, cycloalkyl fused 5- to 6-membered heteroaryl, 5- to 6-membered heterocycloalkyl fused 5- to 6-membered heteroaryl, cycloalkylalkyl, 5- to 6-membered heterocycloalkylalkyl, bicycloalkylalkyl, heterobicycloalkylalkyl, spiroalkylalkyl, spiroheteroalkylalkyl, arylalkyl, 5- to 6-membered heteroarylalkyl, cycloalkyl fused arylalkyl, 5- to 6-membered heterocycloalkyl fused arylalkyl, cycloalkyl fused 5- to 6-membered heteroarylalkyl, and 5- to 6-membered heterocycloalkyl fused 5- to 6-membered heteroarylalkyl are optionally substituted one or more times; R R wherein R wherein R R R R E is selected from the group consisting of a bond, CR U is selected from the group consisting of C(R W X is selected from the group consisting of a bond and (CR g and h are independently selected from 0-2; w is independently selected from 0-4; x is selected from 0 to 2; y is selected from 1 and 2; wherein each of said optional substitution is selected from the group consisting of C pharmaceutically acceptable salt, racemic mixture or stereoisomer thereof.