Patent ID: 8410284
Filing Date: 2013-04-02
Classification: A61P,C07F

Abstract:
1. A compound of structural formula I: or a pharmaceutically acceptable salt thereof, wherein: X is selected from: wherein each CH Y is selected from: wherein cycloalkyl, cycloalkenyl, cycloheteroalkyl, cycloheteroalkenyl, aryl and heteroaryl are unsubstituted or substituted with 1, 2, 3 or 4 substituents selected from R Z is selected from: provided that when R each R wherein each CH R (9) heteroaryl, R each R wherein each CH each R wherein each CH each R wherein each CH each R wherein alkyl is unsubstituted or substituted with 1, 2, 3 or 4 substituents selected from: —OH, oxo, halogen, C each R wherein alkyl and cycloalkyl are unsubstituted or substituted with 1, 2, 3 or 4 substituents selected from: —OH, oxo, halogen, C each R wherein alkyl, cycloalkyl, cycloalkenyl, cycloheteroalkyl, cycloheteroalkenyl, aryl and heteroaryl are unsubstituted or substituted with 1, 2, 3 or 4 substituents selected from: oxo, —OH, —CN, —NH R each R wherein alkyl and aryl are unsubstituted or substituted with 1 or 2 substituents selected from R each R wherein alkyl is unsubstituted or substituted with 1 or 2 substituents selected from R each R wherein aryl and heteroaryl are unsubstituted or substituted with 1, 2 or 3 substituents selected from R each R wherein alkyl is unsubstituted or substituted with 1 or 2 substituents selected from R each R each R wherein alkyl is unsubstituted or substituted with 1 or 2 substituents selected from R each R wherein alkyl and phenyl are unsubstituted or substituted with 1 or 2 substituents selected from halogen and —C n is 0, 1, 2, 3 or 4; m is 0, 1, 2, 3 or 4; p is 0, 1, 2, or 3; q is 0, 1, 2, 3 or 4; r is 0, 1 or 2; and w is 0, 1, 2, 3 or 4.