Patent ID: 6828429
Filing Date: 2004-12-07
Classification: A61K,C07K

Abstract:
An isolated nucleic acid molecule selected from:(a) the polynucleotide sequence of SEQ ID NO:1; (b) an isolated nucleic acid molecule that hybridizes to either strand of a denatured, double-stranded DNA comprising the nucleic acid sequence of (a) under hybridizing conditions comprising 50% formamide and 6Ã—SSC at 42Â° C. with washing conditions comprising 0.5Ã—SSC and 0.1% SDS at 60Â° C., wherein messenger RNA expression of the nucleic acid molecule in NIH 3T3 cells results in about a two-fold increase in the number of colonies of NIH 3T3 cells formed in a colony-forming assay; and (c) an isolated nucleic acid molecule that hybridizes to either strand of a denatured, double-stranded DNA comprising the nucleic acid sequence of (a) under hybridizing conditions comprising 50% formamide and 6Ã—SSC, with washing conditions comprising 0.2Ã—SSC and 0.1% SDS at 68Â° C., wherein messenger RNA expression of the nucleic acid molecule in NIH 3T3 cells results in about a two-fold increase in the number of colonies of NIH 3T3 cells formed in a colony-forming assay.