Patent ID: 7879893
Filing Date: 2011-02-01
Classification: A61K,A61P,C07D

Abstract:
1. A zinc-binding ligand of the following formula (III) wherein: A is a chemical group of the following formula which reversibly binds to a His wherein A AR where C1 is attached to the nitrogen; C AR B is a linker selected from the group consisting of C is a fragment consisting of 0 to 5 neutral amino acids, wherein the individual neutral amino acids are the same or different D is a fragment consisting of 1 to 20 basic amino acids independently selected from the group consisting of Lys and Arg or D-isomers thereof; and X is —OH, —NH or a salt thereof with a pharmaceutically acceptable acid or base, or any optical isomer or mixture of optical isomers, racemic mixture, or tautomeric forms thereof.