Patent ID: 6066332
Filing Date: 2000-05-23
Classification: A61K,G03C,Y10S

Abstract:
A dosage formulation that provides for the release of nanoparticles which comprises:(a) an inner phase that comprises at least one nanoparticle comprising ibuprofen having an average size ranging from 10 to 800 nanometers; and(b) an outer phase that comprises a compound selected from the group consisting of gelatin, collagen hydrolyzates and mixture thereof;wherein said inner phase is negatively charged and said outer phase is positively charged when the dosage formulation is dissolved in an aqueous solution having a pH of less than 9.5 or said inner phase is positively charged and said outer phase is negatively charged when said dosage formulation is dissolved in an aqueous solution having a pH of higher than 3.5.