Patent ID: 6149943
Filing Date: 2000-11-21
Classification: A61K

Abstract:
A particle comprising:a center core of greater than about 90 weight percent microcrystalline cellulose having an average particle size of about 160 to about 220 microns with a particle size standard deviation of from about 75 to about 200 microns;pharmaceutically active material coating the center core of microcrystalline cellulose and a tapped bulk density of from about 0.40 to about 0.45 grams per cubic centimeters;wherein the coated particle is from about 40 to about 75 weight percent microcrystalline cellulose; pharmaceutically active ingredient is from about 25 to about 60 weight percent; and a particle size of from about 200 to about 325 microns and a particle size standard deviation of from about 30 to about 175 microns.