Patent ID: 6686175
Filing Date: 2004-02-03
Classification: A61K,A61P,C07K

Abstract:
An isolated nucleic acid encoding a human CXC Chemokine Receptor 3 (CXCR3) protein, wherein said CXCR3 protein binds one or more chemokines selected from the group consisting of human IP-10 and human Mig, and wherein said nucleic acid hybridizes to a second nucleic acid selected from the group consisting of the complement of SEQ ID NO:1 and the complement of the open reading frame of SEQ ID NO:1 under high stringency wash conditions of 2Ã—SSC, 0.1% SDS at room temperature for ten minutes followed by two washes in 1Ã—SSC, 0.1% SDS at 65Â° C. for thirty minutes and a final wash in 0.5Ã—SSC, 0.1% SDS at 65Â° C. for ten minutes.