Patent ID: 6627648
Filing Date: 2003-09-30
Classification: C07C,C07D

Abstract:
A compound of the formula: whereXâ€² is N and X is selected from the group consisting of Câ€”H, Câ€”F, Câ€”Cl, Câ€”Br, Câ€”I, Câ€”Râ€², Câ€”NRâ€²Râ€³, Câ€”CF3, Câ€”OH, Câ€”CN, Câ€”NO2, Câ€”C2Râ€², Câ€”SH, Câ€”SCH3, Câ€”N3, Câ€”SO2CH3, Câ€”ORâ€², Câ€”SRâ€², Câ€”C(&boxH;O)NRâ€²Râ€³, Câ€”NRâ€²C(&boxH;O)Râ€², Câ€”C(&boxH;O)Râ€², Câ€”C(&boxH;O)ORâ€², C(CH2)qORâ€², Câ€”OC(&boxH;O)Râ€², COC(&boxH;O)NRâ€²Râ€³ and Câ€”NRâ€²C(&boxH;O)ORâ€² where Râ€² and Râ€³ are individually hydrogen, lower alkyl, an aromatic group-containing species, or a substituted aromatic group-containing species, and q is an integer from 1 to 6; m is an integer and n is an integer such that the sum of m plus n is 1, 2, 3, 4, 5, 6, 7, or 8; Zâ€² and Zâ€³ individually represent hydrogen or lower alkyl; E, Eâ€², Eâ€³ and Eâ€²â€³ individually represent hydrogen or a non-hydrogen substituent selected from the group consisting of alkyl, substituted alkyl, halo substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocycl, substituted heterocycl, aryl, substituted aryl, alkylaryl, substituted alkylaryl, arylalkyl and substituted arylakyl; when n is 1, Zâ€² and Eâ€²â€³ and the associated carbon and nitrogen atoms can combine to form a monocyclic ring structure; A, Aâ€² or Aâ€³ are individually hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, heterocyclyl, substituted heterocyclyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, alkylaryl, substituted alkylaryl, arylalkyl and substituted arylalkyl functionalities; when X is carbon bonded to a substituent component, Aâ€² or Aâ€³ can combine with the substituent component to form a saturated or unsaturated, substituted or unsubstituted carbocyclic or heterocyclic ring; when Xâ€² is carbon bonded to a substituent component, A or Aâ€³ can combine with the substituent component to form a saturated or unsaturated, substituted or unsubstituted carbocyclic or heterocyclic ring; Bâ€² is sulfur or oxygen, and wherein the term substituted as used in defining E, Eâ€², Eâ€³ and Eâ€²â€³ and A, Aâ€² and Aâ€³ refers to one or more substituents identified above in connection with the definition of X.