Patent ID: 7994331
Filing Date: 2011-08-09
Classification: A61P,C07D

Abstract:
1. A compound of a formula (I): or its pharmaceutically-acceptable salt thereof, wherein: X ring A is a 6-membered heteroaryl consisting of one nitrogen atom and five carbon atoms as represented by a formula (II): X represents a carbon atom; Het represents a 5 or 6 membered aliphatic, saturated heterocyclic ring having 1-2 oxygen or sulfur atoms, or a 5-6 membered aliphatic, saturated heterocyclic ring having 1-2 oxygen or sulfur atoms, and in addition, 1-2 heteroatoms selected from the group consisting of O, S and N; said 5- or 6-membered aliphatic saturated heterocyclic ring may be mono- to tri-substituted with the same or different —C X R said R R R each R —C —C —C(O)—N(R —S(O) —O—C —S(O) —C(O)—C —C(S)—C —C(S)—C —C(O)—O—C —(CH —N(R —C(O)-aryl optionally substituted with halogen, —C(O)-aromatic hetero ring, —C(O)-aliphatic hetero ring, hetero ring optionally substituted with —C phenyl, said phenyl may be substituted with halogen, —C halogen, CN, formyl, COOH, amino, oxo, hydroxy, hydroxyamidino or nitro; R R R the alkyls of R the alkyls of R m indicates an integer of from 0 to 2; q indicates an integer of from 0 to 2.