Patent ID: 7351339
Filing Date: 2008-04-01
Classification: C07C,C07D,C07F

Abstract:
1. A process for removing acids from a reaction mixture using an auxiliary base, which comprises (1) conducting a reaction, wherein a reaction mixture comprising a product of value and an acid is obtained, wherein the acid is released during the reaction and/or is present during the reaction, and wherein the auxiliary base is present during the reaction or is added to the reaction mixture following the reaction, wherein the reaction is one of (1) a phosphorylation, (2) silylation, (3) sulfurization, (4) acylation with the exception of phosgenations, (5) elimination or (6) substitution, wherein the auxiliary base combines with the acid to form a salt which is liquid at temperatures at which the product of value does not significantly decompose during separating of the liquid salt from the product of value, and (a) the liquid salt of the auxiliary base with (b) the product of value or, if the product of value is entirely or substantially miscible with the salt, a solution of the product of value obtained by combining it with a solvent that reduces miscibility with the salt, forms two immiscible liquid phases, one phase containing (a) and the other phase containing (b), and (2) separating the two immiscible phases from each other, wherein the auxiliary base is selected from the group consisting of the formulae (a) to (r), where R