Patent ID: 8202533
Filing Date: 2012-06-19
Classification: A61K,A61P

Abstract:
1. An immunotherapeutic method for increasing tolerance in a subject to groundnut, comprising: repeatedly administering to the subject one or more proteins derived from groundnut via an epicutaneous route using a skin patch including a backing having a periphery adapted to create a hermetically closed chamber when applied to the subject's skin, the backing carrying said one or more proteins in a dose sufficient to induce an immune reaction in the subject following application of the skin patch to the subject's skin, said one or more proteins being removed from the backing following application of the patch device to the subject's skin and thereafter being delivered to the subject via the epicutaneous route, said administration leading, on repetition, to a progressive increase in tolerance in the subject to groundnut, said one or more proteins being formulated without any adjuvant.