Patent ID: 8728438
Filing Date: 2014-05-20
Classification: A61K,A61P

Abstract:
1. A method of induction of immunosuppression following transplantation comprising administering an effective amount of a coronin 1 modulator for immunosuppression to a patient having a transplant, wherein the coronin 1 modulator is selected from the group consisting of: an anti-coronin 1 polyclonal antibody, monoclonal antibody or an Fab fragment thereof; a humanized antibody comprising the binding portion of an anti-coronin 1 monoclonal antibody; a peptide comprising a coronin 1 peptide selected from a phospho-peptide comprising a peptide of the sequence of SEQ ID NO: 1, 2, 3, 4, 5, 6, 7, or 8, wherein one to five serine and/or threonine residues are phosphorylated; and an RNA selected from