Patent ID: 7094556
Filing Date: 2006-08-22
Classification: A61K,A61P,C07K,C12N,C12Q,C12Y,G01N

Abstract:
1. A method for diagnosing a malignant neoplasm in a mammal, comprising contacting a bodily fluid from said mammal with an antibody or fragment thereof which binds to an human aspartyl (asparaginyl) beta-hydroxylase (HAAH) polypeptide under conditions sufficient to form an antigen-antibody complex and detecting the antigen-antibody complex, wherein an increase in antigen-antibody complex indicates an increase in HAAH level compared to a normal noncancerous control, said increase being indicative of a malignant neoplasm and wherein said monoclonal antibody is produced by a hybridoma selected from the group consisting of hybridoma ATCC designation PTA 3383, hybridoma ATCC designation PTA 3384, and hybridoma ATCC designation PTA 3385.