Patent ID: 9157117
Filing Date: 2015-10-13
Classification: A61B,C12Q

Abstract:
1. A method of improving oocytes from an oocyte donor, comprising: isolating an FMR1 gene from the oocyte donor; measuring the number of triple CGG repeats on each allele of the isolated FMR1 gene by using an assay; determining that the number of triple CGG repeats on at least one of the alleles of the isolated FMR1 gene is less than 26; administering an FMR1 inhibitor to the oocyte donor to reduce expression of the oocyte donor's FMR1 gene when it is determined that the number of triple CGG repeats on at least one of the alleles of the isolated FMR1 gene is less than 26; and thereafter harvesting an oocyte from the oocyte donor.