Patent ID: 6608210
Filing Date: 2003-08-19
Classification: A61P,C07D

Abstract:
A method for producing a compound represented by the formula: wherein the ring A is a benzene ring which may be substituted in addition to the Râ€² group; R1 is hydrogen or an optionally substituted hydrocarbon residue; X is a direct bond or a spacer having an atomic length of two or less between the phenylene group and the phenyl group; Y is â€”Oâ€”, â€”S(O)mâ€” or â€”N(R4)â€” wherein in is an integer of 0, 1 or 2 and R4 is hydrogen or an optionally substituted alkyl group; Râ€² is carboxyl, an ester thereof, an amide thereof or a group capable of fanning an anion or a group convertible there into; n is an integer of 1 or 2; or a pharmaceutically acceptable salt thereof, which comprises deprotecting a compound represented by the formula: â€ƒwherein R is triphenylmethyl, 2-tetrahydropyranyl, methoxymethyl or ethoxy methyl, and the other symbols have the same meanings as defined above; or a pharmaceutically acceptable salt thereof.