Patent ID: 6673542
Filing Date: 2004-01-06
Classification: C12Q,G01N

Abstract:
A method for assaying a sample for the presence of a nucleic acid repair protein, which comprises:a) mixing at least one predetermined single- or double-stranded nucleic acid containing at least one label and containing a nucleic acid repair protein binding domain with a sample which may contain a nucleic acid repair protein, b) incubating the mixture of step a) under conditions which allow the binding of said nucleic acid repair protein to said at least one predetermined single- or double-stranded nucleic acid repair protein binding domain to form a complex, c) adding a nucleic acid-cleaving enzyme or reagent to the mixture of step b), d) incubating the mixture of step 3) under conditions which allow the cleavage of said at least one predetermined single- or double-stranded nucleic acid which has not formed a complex, and e) measuring the amount of said complex to measure said nucleic acid repair protein.