Patent ID: 8796258
Filing Date: 2014-08-05
Classification: A61K,A61P,C07D

Abstract:
1. A compound of structural formula I: or a pharmaceutically acceptable salt thereof, wherein: T is N; U is CR V is CR W is CR X is selected from: Y is selected from: wherein cycloalkyl, cycloalkenyl, cycloheteroalkyl, cycloheteroalkenyl, aryl and heteroaryl are unsubstituted or substituted with 1, 2, 3 or 4 substituents selected from R Z is selected from: wherein each CH each R wherein each CH provided that at least one of and only one of R hydrogen, halogen, —CN, —CF each R R each R wherein each CH2 is unsubstituted or substituted with 1 or 2 substituents selected from: oxo, —(CH each R wherein each CH each R wherein each CH each R wherein alkyl is unsubstituted or substituted with 1, 2, 3 or 4 substituents selected from: —OH, oxo, halogen, C each R wherein alkyl and cycloalkyl are unsubstituted or substituted with 1, 2, 3 or 4 substituents selected from: —OH, oxo, halogen, C each R wherein alkyl, cycloalkyl, cycloalkenyl, cycloheteroalkyl, cycloheteroalkenyl, aryl and heteroaryl are unsubstituted or substituted with 1, 2, 3 or 4 substituents selected from: oxo, —OH, —CN, —NH n is 0, 1, 2, 3 or 4; m is 0, 1, 2, 3 or 4; p is 0, 1, 2, or 3; q is 0, 1, 2, 3 or 4; r is 0, 1 or 2; s is 0, 1, 2, 3 or 4; and t is 0,1,2,3or 4.