Patent ID: 6740644
Filing Date: 2004-05-25
Classification: A61P,C07H,Y02P

Abstract:
A compound selected from the group consisting of:5â€²-O-methyl-N6-(tetrahydrofuran-3R-yl)-adenosine; N6-(2R-hydroxy-(R)-cyclopentyl)-5â€²-O-methyladenosine; 5â€²-O-methyl-N6-(tetrahydropyran-4-yl)-adenosine; N6-(2S-methoxy-(S)-cyclopentyl)5â€²-O-methyladenosine; 5â€²-O-methyl-N6-(2S-methyl-tetrahydro-furan-3R-yl)adenosine; 5â€²-O-methyl-N6-(1 R-methyl-2-phenyl-ethyl)-adenosine; N6-tert-butyl-5â€²-O-methyl-adenosine; N6-(2S-fluoro-(S)-cyclopentyl)-5â€²-O-methyladenosine; N6-(2,3-dihydroxypropyl-amino)-5â€²-methyl-adenosine; N6-rel-[(1 S,4R)-bicyclo[2.2.1]hept-2R-yl]-5â€²-methyl-adenosine; 4-[9-(3R,4S-dihydroxy-5R-methoxymethyl-tetrahydro-furan-2R-yl)9H-purin-6-ylamino]-piperidine-1 -carboxylic acid ethyl ester; 5â€²-O-methyl-N6-[4-(2-methyl-2H-tetrazoly-5-yl)phenyl]adenosine; 5-O-methyl-N6-(tetrahydro-thiopyran-4-yl)adenosine; N6-rel-[(1 R, 5R)-bicyclo[3.2.0]hept-6S-yl]-5â€²-methyl-adenosine; 4-[9-(3R,4S-dihydroxy-5R-methoxymethyl-tetrahydro-furan-2R-yl)-2methyl-9H-purin-6-ylamino]-piperidin-2-one; 5â€²-O-methyl-N6-(1 S-methoxymethyl-2-methyl-propyl)-adenosine; N6-(2-hydroxy-1 R-methyl-ethyl)-5â€²-O-methyl-adenosine; N6-(2-fluoro-1 R-methyl-ethyl)-5â€²-O-methyl-adenosine; N6-(1S-fluoromethyl-2-methoxy-ethyl)-5â€²-O-methyl-adenosine; N6-(3-amino-propyl)-5â€²-O-methyl-adenosine; 2-[9-(3R,4S-dihydroxy-5R-methoxymethyl-tetrahydrofuran-2R-yl)-2methyl-9H-purin-6-ylamino}-ethanesulfonic acid methylamide; N6-cyclopentyl-2-methyl-5â€²-O-methyladenosine; and N6-cyclopropylmethyl-2-methyl-5â€²-O-methyl-adenosine; and physiologically acceptable solvates and salts thereof.