Patent ID: 8722387
Filing Date: 2014-05-13
Classification: C07K,C12N,C12P

Abstract:
1. A recombinant host cell comprising a heterologous polynucleotide encoding a bicarbonate transporter, wherein the heterologous polynucleotide: (a) encodes a bicarbonate transporter having at least 90% sequence identity to SEQ ID NO: 2; (b) hybridizes under high stringency conditions with the full-length complementary strand of SEQ ID NO: 1, or the cDNA sequence thereof; or (c) has at least 90% sequence identity to SEQ ID NO: 1, or the cDNA sequence thereof; wherein the host cell is capable of producing a greater amount of a C4-dicarboxylic acid compared to the host cell without the heterologous polynucleotide when cultivated under the same conditions.