Patent ID: 7078492
Filing Date: 2006-07-18
Classification: A61K,A61P,C07K

Abstract:
1. A monoclonal antibody or an antigen-binding fragment thereof that specifically binds the capsular polysaccharide of Streptococcus pneumoniae serotype 3 ( S. pneumoniae PPS-3), wherein said antibody or fragment comprises a heavy chain amino acid sequence comprising an amino acid sequence selected from the group consisting of: (a) the amino acid sequence encoded by the DNA sequence set forth in SEQ ID NO: 1; (b) the amino acid sequence of residues 31 to 104, inclusive, of the amino acid sequence encoded by the DNA sequence set forth in SEQ ID NO: 1; and (c) the CDR1, CDR2 and CDR3 amino acid sequences encoded by the DNA sequence set forth in SEQ ID NO: 1.