Patent ID: 6784193
Filing Date: 2004-08-31
Classification: A61P,C07B,C07C,C07D

Abstract:
A compound of formula whereinR and R2 together with the nitrogen atom to which they are attached form non-aromatic heterocyclene; R1 is a group of the formula R3, R3â€², R6, R7, and R8 are independently of each other hydrogen or deuterium; R4 is hydrogen or alkyl; R5 is hydrogen or alkyl; R9 is amino, alkyl, aryl, heterocyclyl, or mercapto; and, if X is oxygen, R9 is additionally hydrogen; R10 is hydrogen or alkyl; and X is sulphur, oxygen, NR10, or N+(Râ€²10)2 wherein Râ€²10 is alkyl in the presence of an appropriate anion.