Patent ID: 6479668
Filing Date: 2002-11-12
Classification: C07D

Abstract:
A method for producing a pyrrolidine compound of formula (1) wherein R1 is hydrogen, a halogen, a cyano group, a nitro group, a hydroxyl group, an alkoxyl group, a carboxyl group, an alkoxycarbonyl group, an acyl group, a carbamoyl group, a sulfide group, a sulfinyl group, a sulfonyl group, a sulfamide group, or a C1-C10 alkyl group, cycloalkyl group, aryl group, or aralkyl group, unsubstituted or substituted; R2 and R3 each independently represent a C1-C10 alkyl group, cycloalkyl group, aryl group, or aralkyl group unsubstituted or substituted; and Nu is selected from the group consisting of a hydroxyl, alkoxyl and amino, unsubstituted or substituted; comprising oxidizing a compound of formula (3) wherein R1 is hydrogen, a halogen, a cyano group, a nitro group, a hydroxyl group, an alkoxyl group, a carboxyl group, an alkoxycarbonyl group, an acyl group, a carbamoyl group, a sulfide group, a sulfinyl group, a sulfonyl group, a sulfamide group, or a C1-C10 alkyl group, cycloalkyl group, aryl group, aralkyl group unsubstituted or substituted; R2 and R3 each independently represent a C1-C10 alkyl group, cycloalkyl group, aryl group, aralkyl group, unsubstituted or substituted;with at least one peroxide in the presence of at least one acid.