Patent ID: 8895503
Filing Date: 2014-11-25
Classification: A61K,A61P,C07K

Abstract:
1. A method for nasal administration of a drug comprising administering to the nasal mucosa of a patient in need thereof an effective amount of the pharmaceutical composition comprising a mixture of a peptide hormone or cytokine and any one of (a) to (c) below, with the proviso that a C-terminal amidated peptide is excluded: (a) a peptide having the amino acid sequence shown in SEQ ID NO:1; (b) a peptide having the same amino acid sequence as shown in SEQ ID NO:1, except that one or several amino acids are deleted, substituted and/or added, said peptide having nasal mucosal permeability; and (c) a peptide having an amino acid sequence represented by the reverse sequence of (a) or (b), said peptide having nasal mucosal permeability wherein the peptide hormone or cytokine is not covalently bonded to any of (a) to (c).