Patent ID: 8293788
Filing Date: 2012-10-23
Classification: A61P,C07C,C07D

Abstract:
1. A method for treating psoriasis, ulcerative colitis, melanoma, angiogenesis, chronic obstructive pulmonary disease (COPD), bullous pemphigo, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and in the prevention and treatment of ischemia-reperfusion injury, comprising administering to a patient in need thereof a therapeutically effective amount of a 2-(R)-phenylpropionic acid derivative compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein: R′ group is selected from: when R′ is H, R is selected from Ra and Rb together with the nitrogen atom to which they are bound, form a heterocycle from 3 to 7 members of formula (II), wherein W represents a single bond, O, S, N-Rc, Rc being H, C when R′ is OH, R is selected from H, C