Patent ID: 9102688
Filing Date: 2015-08-11
Classification: A61K,A61P,C07D

Abstract:
1. A method for treating iron metabolism disorders selected from the group consisting of iron deficiency diseases and iron deficiency anemias, the method comprising administering to a patient in need thereof compounds of the formula (I) wherein R defining compounds according to the formula (Ia) wherein R hydrogen, halogen and alkyl, which may be substituted with 1 to 3 identical or different substituents, selected from the group consisting of: R hydrogen and alkyl as defined for R R hydrogen, halogen, aminocarbonyl, wherein the amino group may be substituted as defined for R amino, as defined for R alkyl as defined for R alkoxycarbonyl (—(C═O)—O-alkyl), with alkyl as defined for R alkoxy (alkyl-O), with alkyl as defined for R heterocyclyl, which may be substituted with 1 to 3 substituents as defined for aryl for R R hydrogen, halogen, cyano, aminocarbonyl, as defined for R amino, as defined for R alkyl, as defined for R acyl, including aliphatic acyl (alkanoyl=alkyl-CO—), with alkyl as defined for R alkoxy, as defined for R heterocyclyl, as defined for R R hydrogen, halogen, alkyl, as defined for R alkoxy, as defined for R R hydrogen and alkyl, as defined for R wherein X is C or N; R hydrogen, hydroxyl, carboxyl, halogen, cyano, nitro, amino, as defined for R alkyl, as defined for R acyl, as defined for R alkoxycarbonyl, as defined for R acyloxy (—O—(C═O)-alkyl, —O—(C═O)-aryl, —O—(C═O)-heterocyclyl) with acyl, as defined for R alkoxy, as defined for R aryloxy (aryl-O), with aryl as defined for R aryl, as defined for R heterocyclyl, as defined for R and defining compounds according to the formula (Ib) wherein R hydrogen, sulfonyl (—SO alkyl, as defined for R acyl, as defined for R alkoxycarbonyl, as defined for R aryl, as defined for R heterocyclyl, as defined for R R hydrogen, hydroxyl, halogen, cyano, carboxyl, amino, as defined for R alkyl, as defined for acyl, as defined for R alkoxycarbonyl, as defined for R acyloxy, as defined for R alkoxy, as defined for R aryloxy, as defined for R alkenyl, which may be substituted with 1 to 3 identical or different substituents, selected from hydroxyl, halogen and alkoxy, aryl, as defined for R heterocyclyl, as defined for R or pharmaceutically acceptable salts thereof.