Patent ID: 6288249
Filing Date: 2001-09-11
Classification: A61P,C07C

Abstract:
A vitamin D compound of formula (I): ##STR14##wherein:R.sub.1 is a hydrogen atom or a substituent selected from the group consisting of OH, CH.sub.2 OH, CH.sub.2 CH.sub.2 OH, CH.sub.2 CH.sub.2 CH.sub.2 OH, OCH.sub.3, OCH.sub.2 OH, OCH.sub.2 CH.sub.2 OH and OCH.sub.2 CH.sub.2 CH.sub.2 OH;R.sub.2 is a hydrogen atom or a substituent selected from the group consisting of OCH.sub.3, OCH.sub.2 OH, CH.sub.m (CH.sub.2 OH).sub.n (CH.sub.2 CH.sub.2 OH).sub.p, (CH.sub.2).sub.q OH and O(CH.sub.2).sub.r OH;wherein:m is 0 or 1; p, q, and n are independently 0, 1, 2 or 3; r is 1, 2 or 3;and m+n+p=3;with the proviso that at least one of R.sub.1 and R.sub.2 contains at least one OH group and;with the proviso that both R.sub.1 substituents are the same;R.sub.3 is a straight or branched, saturated or unsaturated aliphatic hydrocarbon having from 6 to 13 carbon atoms which may be substituted with one or more substituents selected from the group consisting of hydroxy and fluoro.