Patent ID: 6592545
Filing Date: 2003-07-15
Classification: A61M

Abstract:
A needleless syringe for accelerating particles into a target tissue surface of a vertebrate subject, said syringe comprising:(a) a body having a lumen therein, wherein said lumen has an upstream terminus and a downstream terminus and the upstream terminus of the lumen is capable of interfacing with an energizing means; and (b) a diaphragm arranged adjacent to the downstream terminus of the lumen, said diaphragm having an internal surface facing the lumen and an external surface, wherein said diaphragm is moveable between an initial position in which a concavity is provided on the external surface of the diaphragm, and a dynamic position in which the external surface of the diaphragm is substantially convex, characterized in that the external surface of said diaphragm comprises one or more topographical features which selectively retain particles on the external surface of the diaphragm when in its initial position.