Patent ID: 6998110
Filing Date: 2006-02-14
Classification: A61K,A61P

Abstract:
1. A method for administering an effective amount of a pharmacologically active compound to a mammal to provide transmucosal absorption of a pharmacologically effective amount of the active compound through the oral mucosa of the mammal to the systemic circulatory system of the mammal, comprising: spraying the oral mucosa of the mammal with a buccal spray composition, containing a pharmacologically active compound dissolved in a pharmacologically acceptable solvent, comprising in weigh percent of the composition: an active compound in an amount of between 0.1 and 25 percent selected from the group consisting of a biologically active peptide, central nervous system active amine, sulfonyl urea, antibiotic, antifungal, sleep inducer, antiasthmatic, antiemetic, antiviral, histamine H-2 receptor antagonist, barbiturate, prostaglandin, or bronchial dilator; a polar solvent in an amount between 10 and 97 percent; and a propellant in an amount between 2 and 10 percent, wherein said propellant is a C