Patent ID: 8759401
Filing Date: 2014-06-24
Classification: A61K

Abstract:
1. An aqueous gel formulation consisting of water, lidocaine hydrochloride, a viscoelastic polymer, and sodium chloride, wherein the lidocaine hydrochloride is present in an amount of 35 mg per ml of the formulation and the sodium chloride is present in an amount of 9 mg per ml of the formulation, wherein the aqueous gel formulation has a viscosity of 2000 to 10,000 cps at 25° C., is free of preservatives and phosphate buffer, has an osmolality of 250 to 350 mOsm/kg, and is sterile having less than about 100 particles of 50 microns particle size or greater per ml of the aqueous gel formulation, wherein the viscoelastic polymer is hydroxypropylmethylcellulose, the pH of the aqueous gel formulation is from 5.0 to 7.0, and the aqueous gel formulation is suitable for administration to the eye of an animal.