Patent ID: 7423157
Filing Date: 2008-09-09
Classification: A61P,C07D

Abstract:
1. A compound of formula (I) represented by the formula wherein R represents phenyl, naphthyl, thienyl, furyl, thiazolyl, oxadiazolyl, thiadiazolyl, imidazolyl, pyrazolyl, pyridinyl, pyrimidinyl, benzothienyl, benzofuryl, indolyl, or benzisoxazolyl, optionally substituted by up to four substituents independently selected from alkyl, halo-lower alkyl, phenyl, optionally substituted heteroaryl, hydroxy, lower alkoxy, lower alkoxy-lower alkoxy, amino, monoalkylamino, dialkylamino, aminocarbonylamino wherein each of the two amino groups is optionally substituted by alkyl, alkenyl, alkinyl, heterocyclylcarbonylamino wherein heterocyclyl is bound via a nitrogen atom, lower alkoxycarbonylamino, lower alkylcarbonylamino wherein alkyl is optionally substituted by alkoxy or optionally substituted amino; lower alkenylcarbonylamino wherein alkenyl is optionally substituted by alkoxy or optionally substituted amino; lower alkylsulfinyl, lower alkylsulfonyl, lower alkylcarbonyl, carboxy, lower alkoxycarbonyl, cyano and halogen; and wherein two adjacent substituents on said groups represented by R may form a 5 or 6 membered carbocyclic or heterocyclic ring; X represents oxygen or a group C═Y, wherein Y stands for oxygen; Q represents N; R R R R R tautomers and pharmaceutically acceptable salts thereof.