Patent ID: 6210906
Filing Date: 2001-04-03
Classification: C07K,G01N,Y10S

Abstract:
A method for determining the amount of Lp(a) in a sample comprising the steps of:(a) contacting said sample and an Lp(a) specific binding agent coupled to a solid support wherein said Lp(a) specific binding agent is a monoclonal antibody or fragment thereof that binds to substantially all Lp(a) via kringle 5 of apo(a), to plasminogen at less than 1% of Lp(a) binding and to LDL, VLDL, IDL and HDL at less than 2% of Lp(a) binding, for a time and under conditions to form binding agent-Lp(a) complexes; and(b) determining the amount of Lp(a) bound to said binding agent-Lp(a) complexes.