Patent ID: 6572845
Filing Date: 2003-06-03
Classification: A61K,A61Q

Abstract:
A method of formulating a hair treatment composition, the method comprising steps of:selecting a human individual on the basis of that individual having appealing hair characteristics obtaining at least one nucleic acid, each of which encodes a different keratin allelic variant that is present in hair of thc human individual; introducing each of the at least one obtained nucleic acids into an expression vector so that a population of expression constructs, each of which encodes at least one keratin allelic variant is produced; introducing each expression construct into a host cell so that a population of host cells, each of which has received an individual expression construct and expresses a non-crosslinked keratin allelic variant therefrom, is produced; identifying those host cells in the population of host cells that express one of the at least one keratin allelic variants in a manner that does not result in cross-linking of the at least one produced keratin allelic variants; purifying each of the at least one keratin allelic variants from the host cell that produces them; and combining the purified keratin allelic variants with one another and also with components of a hair treatment composition to form a hair treatment composition.