Patent ID: 6511999
Filing Date: 2003-01-28
Classification: C07D

Abstract:
A compound represented by the general formula I. whereinm is an integer of from 1 to 3; n is 0 or an integer of from 1 to 4; R is selected from the group consisting of CO2H, CO2 R6, CH2OH, CH2O R6 and CONR3R4;R1 and R2 are independently selected from the group consisting of H, R6, C2-C6 alkenyl, C2-C6 alkynyl, C3-C7 cycloalkyl, C4-C12 alkylcycloalkyl, C6-C10 aryl, C7-C12 alkyl aryl radicals and nitrogen or sulfur-substituted derivatives thereof, wherein one or more of the hydrogen or carbon atoms in said radicals is replaced with a halogen, nitrogen or sulfur-containing radical wherein said nitrogen or sulfur-containing radical is selected from the group consisting of NO2, N(R7)2, CON(R7)2, SR7 and CN, wherein R7 is selected from the group consisting of H and C1-C6 alkyl; R3 and R4 are selected from the group consisting of H and R6; and X is selected from the group consisting of H, R6, hydroxy, N(R6)2, CON(R6)2, SR6, halogen, COOR6, NO2, CN and OR6, wherein R6 is C1-C6 alkyl; Y is O or S; Z is N or CH or a pharmaceutically acceptable salt thereof.