Patent ID: 8420333
Filing Date: 2013-04-16
Classification: A61P,C07K,G01N,Y10T

Abstract:
1. A method for determining whether early stage cancer is present in a subject comprising: detecting the expression level of GASP-1 in the subject by detecting the amount of GASP-1 peptide fragments present in a biological sample of the subject, wherein detecting the amount of GASP-1 peptide fragments present in the biological sample comprises (i) contacting the biological sample with a binding agent that selectively binds GASP-1 peptide fragments and (ii) detecting the amount of GASP-1 peptide fragments that bind to the binding agent, wherein the subject has not been diagnosed with late stage cancer, wherein a higher expression level of GASP-1 in the subject compared to the expression level of GASP-1 in a cancer-free subject or a cancer-free biological sample indicates the presence of early stage cancer in the subject.