Patent ID: 6437146
Filing Date: 2002-08-20
Classification: A61P,C07D

Abstract:
A compound of the formula: whereinR1 is aryl which is unsubstituted or substituted with halogen(s), R2 is aryl which is unsubstituted or substituted with halogen(s), X is single bond â€ƒor SO2, R3 and R4 are independently hydrogen or suitable substituent, (wherein X is â€ƒneither R3 nor R4 is hydrogen), R3 and R4, when linked together form â€ƒis N-containing heterocyclic group which is unsubstituted or substituted with one or more suitable substituent(s), R5 is (1) hydrogen, (2) hydroxy, (3) carboxy, or (4) protected carboxy, A1 is lower alkylene or single bond, â€ƒis cyclo(C3-C9)alkane or cyclo(C5-C9)alkene, or a pharmaceutically acceptable salt thereof.