Patent ID: 6530371
Filing Date: 2003-03-11
Classification: A61M,B05B

Abstract:
A method of intranasally delivering at least one substance in at least two doses, comprising the steps of:grasping a pre-assembled drug delivery system with a thumb and two forefingers of one hand, said drug delivery system including a drug container and a holder, with the drug container including a barrel, a first end extending from the barrel, and a stopper slidably positioned within the barrel and the holder having a distal portion and a proximal portion, with the distal portion being assembled to the proximal portion, with the drug container secured therein, and the proximal portion acting as a plunger rod during activation of the system; inserting an end of said drug container into a first nostril of a person to whom the substance is to be intranasally delivered; squeezing together the thumb and two forefingers of the one hand to apply sufficient force to break a first frangible bridge extending across a slot to insure the application of a minimum force; moving the proximal portion of the holder towards the distal portion of the holder a first predetermined distance during a first motion as a result of continuing to squeeze together the thumb and two forefingers to cause a first displacement of the stopper and expulsion of a first predetermined amount of a substance contained in the chamber of the drug container barrel into said first nostril; removing the end of said drug container from said first nostril while relaxing the squeezing force being applied and inserting the end of said drug container into a second nostril of the person to whom the substance is to be intranasally delivered; squeezing together the thumb and two forefingers to apply sufficient force to break a second frangible bridge extending across the slot to insure application of a minimum force; and moving the proximal portion of the holder towards the distal portion of the holder a second predetermined distance during a second motion as a result of continuing to squeeze together the thumb and two forefingers to cause a second displacement of the stopper and expulsion of a second predetermined amount of the substance contained in the chamber of the drug container barrel into said second nostril.