Patent ID: 8222369
Filing Date: 2012-07-17
Classification: A61P,C07D,C07K

Abstract:
1. A process for preparing a compound of the following formula (I): wherein W is CH or N, L wherein each R L L L R said cycloalkyl, aryl or Het being substituted with R wherein R or R R wherein R D is a 5 to 10-atom unsaturated alkylene chain; R C A is an amide of formula —C(O)—NH—R or A is a carboxylic acid or a pharmaceutically acceptable salt or ester thereof; said process comprising reacting a compound of formula (3) with a compound of formula QUIN, wherein R and when A is a protected carboxylic acid group in formula (I), optionally subjecting the compound of formula (I) to de-protection conditions to obtain a compound of formula (I) wherein A is a carboxylic acid group; and when A is a carboxylic acid group in the resulting compound of formula (I), optionally coupling this compound with a sulfonamide of formula R