Patent ID: 9102966
Filing Date: 2015-08-11
Classification: A61P,C07H,C12P,Y02P

Abstract:
1. Method for the synthesis of compounds of human milk oligosaccharides of Formula 1-3D and salts thereof wherein Y is independently an N-acetyl-lactosaminyl group optionally substituted with a sialyl and/or fucosyl residue, integer p is independently 0, 1 or 2, R wherein R wherein R wherein R 1 is as defined above and is a group removable by hydrogenolysis, in which a sialyl donor of formula SA-OR 3 is H or fucosyl unit, Y is independently an N-acetyl-lactosaminyl group optionally substituted with a sialyl and/or fucosyl residue, p is an integer independently selected from 0, 1 or 2, R 8 is selected form Formulae 5 or 6, wherein R 6 is H or fucosyl residue, R 7 H or α-sialyl moiety, and R 9 is selected from the group consisting of H, α-sialyl moiety, a group of Formula 5 and a group of Formula 6, under the catalysis of an enzyme having transsialidase activity.