Patent ID: 6809093
Filing Date: 2004-10-26
Classification: A61K,A61P,C07C,C07D

Abstract:
A compound having the structure: or an optical isomer, diastereomer, enantiomer, pharmaceutically-acceptable salt, wherein:(a) w is 0 to 6, x is 0 to 10, and t is 0 to 6; (b) A is a substituted heterocyclic group having about 4 to about 9 members; (c) R1 is selected from the group consisting of a hydrogen atom, a hydroxyl group, a hydrocarbon group, a substituted hydrocarbon group, a heterogeneous group, a substituted heterogeneous group, a carbocyclic group, a substituted carbocyclic group, a heterocyclic group, a substituted heterocyclic group, an aromatic group, a substituted aromatic group, a heteroaromatic group, and a substituted heteroaromatic group, (d) R2 and R3 are bonded together to form a substituted piperidyl group; (e) R4 is selected from the group consisting of â€”CH(R1)â€”; (f) R5 is selected from the group consisting of â€”NR6(R7)â€” and â€”OrR6â€”; wherein r is equal to 1; (g) R6 is selected from the group consisting of a hydrocarbon group, a substituted hydrocarbon group, a heterogeneous group, a substituted heterogeneous group, a carbocyclic group, a substituted carbocyclic group, a heterocyclic group, a substituted heterocyclic group, an substituted aromatic group, a heteroaromatic group, and a substituted heteroaromatic group; (h) R7 is selected from the group consisting of a hydrogen atom and R6: (i) R8 is selected from the group consisting of a hydrocarbon group, a substituted hydrocarbon group, a heterogeneous group, a substituted heterogeneous group, a carbocyclic group, a substituted carbocyclic group, a heterocyclic group, a substituted heterocyclic group, an aromatic group, a substituted aromatic group, a substituted heteroaromatic group, and (j) R9 is selected from the group consisting of a hydrogen atom or a hydrocarbon group.