Patent ID: 6288237
Filing Date: 2001-09-11
Classification: A01N,A61P,C07D,C07F

Abstract:
Epothilon derivative of formula 2 ##STR6##whereinR=H, C.sub.1-4 alkyl; R.sup.1, R.sup.2, R.sup.3 =H, C.sub.1-6 alkyl, C.sub.1-6 acyl, benzoyl, C.sub.1-4 trialkylsilyl, benzyl, phenyl, or benzyl or phenyl each substituted by C.sub.1-6 alkoxy, C.sub.6 alkyl, hydroxy or by halogen; the alkyl and acyl groups contained in the radicals are straight-chain or branched radicals; and Y and Z are either identical or different and each represents hydrogen, halogen, pseudohalogen, OH, O--(C.sub.1-6)acyl, O--(C.sub.1-6)alkyl or O-benzoyl, or together form the O atom of an epoxy group or one of the C--C bonds of a C.dbd.C double bond.