Patent ID: 6150416
Filing Date: 2000-11-21
Classification: A61K,A61P,C07D

Abstract:
A compound having the formula: ##STR47## wherein: R.sub.1, R.sub.2 and R.sub.3 are members independently selected from the group consisting of alkyl, substituted alkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, aryloxyalkyl, substituted aryloxyalkyl, heteroaryl, substituted heteroaryl, heteroarylalkyl, substituted heteroarylalkyl, heterocycles, substituted heterocycles, heterocyclicalkyl and substituted heterocyclicalkyl; provided R.sub.2 is not a radical which is a nitrogen-bonded cyclic .alpha.-amino acid or ester thereof;R.sub.5 and R.sub.6 are independently selected from the group consisting of hydrogen, halogen, alkyl, substituted alkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, aryloxyalkyl and substituted aryloxyalkyl; or R.sub.5 and R.sub.6 and the carbons to which they are bound join to form an optionally substituted carbocyclic or heterocyclic fused ring system having a total of 9- or 10-ring atoms within said fused heterocyclic ring system, said heterocyclic fused ring system containing at least one member selected from the group consisting of a nitrogen atom, an oxygen atom and a sulfur atom.