Patent ID: 7432259
Filing Date: 2008-10-07
Classification: A61P,C07D

Abstract:
1. A compound of formula (Ia) wherein R 1 is hydrogen, C —(C R 2 is hydrogen, C C —(C —(C benzyl, optionally substituted by one or more halo, halo-C phenyl, optionally substituted by one or more halo, halo-C R 3 is hydrogen, halo, or C R 4 is hydrogen, halo, C halo-C C halo-C —O—C R 5 is hydrogen, halo, C C or R 4 and R 5 are bound together to form a ring with the benzo moiety, wherein —R R 6 is hydrogen, C —(C —(C —O-benzyl, optionally substituted by one or more halo, halo-C nitro, halo, cyano, C halo-C halo-C —(C phenyl, optionally substituted by one or more halo, halo-C —(C or R 5 and R 6 are bound together to form a ring with the benzo moiety, wherein —R —C(O)—(CH —O—(CH R 7 is hydrogen or C 1-6 -alkyl; R 8 , R 9 , R 10 , and R 11 are each independently hydrogen, halo, C 1-6 -alkyl, halo-C 1-6 -alkyl, C 1-6 -alkoxy or halo-C 1-6 alkoxy; R a , R b , R i and R j are each independently hydrogen, C —(C or R R c , R d , R g and R h are each independently hydrogen, C —C(O)R R R R f is selected from hydrogen, C C phenyl, optionally substituted by one or more halo, halo-C or a pharmaceutically acceptable salt thereof.