Patent ID: 8207263
Filing Date: 2012-06-26
Classification: C07K

Abstract:
1. A product comprising a support and at least one membrane protein attached to the surface thereof, wherein said membrane protein is attached to said support through an amphiphilic molecule with which said membrane protein is complexed, the binding to the support being done through the amphiphilic molecule, wherein the amphiphilic molecule is a vinyl polymer of the formula (I): wherein: Ra Rb n is an integer equal to or greater than 2; x is between 0.25 and 2.5; and the average molecular weight is between 500 and 100,000, wherein the binding of the amphiphilic molecule to the support is mediated by a specific receptor-ligand binding between at least one functional group in the amphiphilic molecule and at least one functional group at the support surface, or a covalent bond between at least one reactive functional group in the amphiphilic molecule and at least one reactive functional group at the support surface, and wherein the polymer of formula (1) further comprises a percentage of between 0 and 4% of a monomer of the formula wherein: Raa is a hydrogen atom or a methyl radical; Rbb represents a COORcc, or —COSRcc or —CORcc or CONRccRdd group; Rcc represents the functional group in the amphiphilic molecule providing a first half of a receptor-ligand pair or a first half of a chemical reactive pair; and Rdd represents a (C