Patent ID: 7132441
Filing Date: 2006-11-07
Classification: A61K,A61P,H01M,Y02E

Abstract:
1. A pharmaceutical composition comprising a pharmaceutically-acceptable carrier and a therapeutically-effective amount of a 5lipoxygenase selective inhibitor, a cyclosporin compound and a cyclooxygenase-2 selective inhibitor selected from flosutide 5-bromo-2-(4-fluorophenyl)-3-f4-(methylsulfonyl)phenyll-thiophene, N-[2-cyclohexyloxy)-4-nitrophenyll-methanesulfonamide, 1,1-dioxide-4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide, N-[6-(2,4difluorophenoxy)-2,3-dihydro-1-oxo-1 H-inden-5-yl]-methanesulfonamide and compounds of Formula I or a pharmaceutically acceptable salt of a compound having Formula I: wherein A is a 5-or 6-member ring substituent selected from partially unsaturated or unsaturated heterocyclo and carbocyclic rings; wherein R wherein R wherein R