Patent ID: 6514970
Filing Date: 2003-02-04
Classification: A61P,C07D

Abstract:
A compound of Formula (I): wherein:R1 is isobutyl, isopropyl, benzyl, carbamoylmethyl; R2 is methyl, phenyl, naphthyl, indolyl, benzimidazolyl, quinolinyl, furanyl, thiopheneyl, pyridyl, benzofuranyl, or benzothiophenyl, substituted or unsubstituted by one or two halogen, methyl, methoxy, or methylenedioxy groups; R3 is hydrogen, halogen, methyl, methoxy, nitro, or 2,3-(1,3-butadien-1,4-yl); R4 is 3-dimethylaminopropyl, 2-(pyrrolidin-1-yl)ethyl, 2-(1-morpholino)ethyl, 2-(N-methyl anilino)ethyl, 2-(1-piperazinyl)ethyl, 2-(1-pyrrolidinonyl)ethyl, (1-methylpyrrolidin-2(S)-yl)methyl, 1-methylpyrrolidin-3(Â±)-yl, 1-benzylpiperidin-4-yl, (6-methylpyrid-2-yl)methyl, 3-dimethylamino benzyl, 2(S)-(aminocarbonyl)pyrrolidin-4(S)-yl, pyrrolidin-3(S)-yl, piperidin-4-yl, pyrrolidin-3(R)-yl, or cis-4-aminocyclohexyl; and n is 1 or 2; or a pharmacologically acceptable salt thereof.