Patent ID: 6403794
Filing Date: 2002-06-11
Classification: A01N,C07D

Abstract:
A substituted biguanide and/or acid adducts thereof of the formula (II) whereinR1 represents unsubstituted or hydroxyl-, cyano-, halogen- or C1-C4-alkoxy-substituted alkyl having 2 to 4 carbon atoms or represents unsubstituted or cyano-, halogen- or C1-C4-alkyl-substituted cycloalkyl having 3 to 6 carbon atoms, R2 represents hydrogen, methyl or ethyl, A represents oxygen or methylene, and Ar represents in each case unsubstituted or substituted phenyl, naphthyl or heterocyclyl, where the possible heterocyclyl groupings are selected from the group below: furyl, benzofuryl, dihydrobenzofuryl, tetrahydrofuryl, thienyl, benzothienyl, thiazolyl, benzothiazolyl, oxazolyl, benzoxazolyl, thiadiazolyl, oxadiazolyl, pyrazolyl, pyrrolyl, quinolinyl, isoquinolinyl, pyridinyl and pyrimidinyl, and where the possible substituents are in each case selected from the group below: hydroxyl, cyano, nitro, halogen; unsubstituted or hydroxy-, cyano- or halogen-substituted alkyl or alkoxy having in each case 1 to 6 carbon atoms; unsubstituted or halogen-substituted alkylcarbonyl, alkoxycarbonyl, alkylthio, alkylsulphinyl or alkyl-sulphonyl having in each case 1 to 6 carbon atoms in the alkyl groups; unsubstituted or hydroxyl-, cyano-, nitro-, halogen-, C1-C4-alkyl, C1-C4-halogenoalkyl-, C1-C4-alkoxy- or C1-C4-halogenoalkoxy-substituted phenyl or phenoxy; and unsubstituted or halogen-substituted methylenedioxy or ethylenedioxy; with the proviso that said substituent cannot be methyl, and with the proviso that when Ar represents phenyl or substituted phenyl, A does not represent methylene.