Patent ID: 6180116
Filing Date: 2001-01-30
Classification: A61K,A61P,A61Q,C07D

Abstract:
A histidine derivative represented by the formula (I): ##STR5##whereinn is an integer from 0 to 5,n' is an integer from 1 to 16,R represents a side chain of an amino acid,X represents a radical, selected from the group consisting of --NH--CO--, --SO.sub.2 --, --NH--CO--CO--, and --O--CO--CO--,R' represents an optionally hydroxylated, saturated or unsaturated, linear or branched C.sub.6 to C.sub.22 alkyl radical or a C.sub.6 to C.sub.22 aminoalkyl radical, wherein the amine functional group of the C.sub.6 to C.sub.22 aminoalkyl radical is optionally protected as an acetamide or is substituted by one or two lower alkyl groups, andQ.sup.+ represents H.sup.+ or an organic or inorganic cation,or an addition salt of a histidine derivative represented by the formula (I) with an organic or inorganic acid.