Patent ID: 7393696
Filing Date: 2008-07-01
Classification: A61D,G01N

Abstract:
1. A pregnancy assay device for determining pregnancy or lack of pregnancy of a ruminant and/or ungulate animal, said assay device comprising: (a) a cassette; and (b) at least one test strip housed within said cassette; (c) first antibodies specific to a Group A antigen disposed in a horizontal or vertical line on said test strip, said first antibodies being selected from the group consisting of Interferon-stimulated Gene 17 (ISG17; Mx; Granulocyte Chemotactic Protein (GCP-2); 2′,5′ oligoadenylate synthetase; β2 microglobulin; Interferon Regulatory Factors 1 and 2; 1-8U; 1-8D; Leu-13/9-27; COX-2; Early Pregnancy Factor (EPF), Bovine Antigen Glycoprotein (BAG); Pregnancy Specific Protein B (PSPB) and Pregnancy Associated Glycoproteins 1, 4, 5 and 9 (PAG-1, PAG-4, PAG-5, and PAG-9); or (d) binding partners specific to each such complex on said test strip; and (e) labels attached to said binding partners; wherein detection of said labels forming a plus sign on said test strip indicating binding of Group A or Group B antibodies to Group A or Group B antigens and also binding of Group C antibodies to Group C antigens indicates the animal is pregnant; and failure to detect said labels indicating binding of Group C antibodies to Group C antigens indicates the animal is not pregnant.