Patent ID: 8202912
Filing Date: 2012-06-19
Classification: A61K,A61P

Abstract:
1. A composition comprising: (a) a drug in a pharmaceutically acceptable solubility-improved form that is a crystalline highly soluble salt form other than the crystalline hydrochloride salt; and (b) a concentration-enhancing polymer selected from the group consisting of hydroxypropyl methyl cellulose acetate, hydroxypropyl methyl cellulose, hydroxypropyl cellulose, methyl cellulose, hydroxyethyl methyl cellulose, hydroxyethyl cellulose acetate, hydroxyethyl ethyl cellulose, and mixtures thereof wherein said drug alone has an aqueous solubility of up to 2 mg/mL at pH 1 to 8, said composition is not a dispersion and said drug and said polymer are present as particles in a dry physical mixture.