Patent ID: 7026507
Filing Date: 2006-04-11
Classification: A61K,A61P,C07C

Abstract:
1. A process for preparing a solid formulation of sodium 3-hydroxy-3-methylbutyrate of the formula: comprising (1) reacting 4,4-dimethyloxetan-2-one with aqueous sodium hydroxide to form a solution of sodium 3-hydroxy-3-methylbutyrate, (2) optionally concentrating said solution, (3) combining (i) said solution and (ii) synthetic silica, (4) obtaining a solid formation from the combination of (i) said solution and (ii) the synthetic silica, of sodium 3-hydroxy-3-methylbutyrate and synthetic silica, and (5) optionally drying the solid formulation of sodium 3-hydroxy-3-methylbutyrate and synthetic silica.