Patent ID: 8258158
Filing Date: 2012-09-04
Classification: A61P,C07D

Abstract:
1. A compound of formula (I), wherein R R R R R R A A n is zero, 1, 2, 3, 4 or 5; and pharmaceutically acceptable salts thereof; with the proviso that, when R with the further proviso that said compound is not 1-(toluene-4-sulfonyl)-piperidine-4-carboxylic acid (4-trifluoromethoxy-phenyl)-amide; 1-(toluene-4-sulfonyl)-piperidine-4-carboxylic acid [2-(4-difluoromethoxy-phenyl)-ethyl]-amide; 1-benzenesulfonyl-piperidine-4-carboxylic acid (4-isopropyl-phenyl)-amide; 1-(toluene-4-sulfonyl)-piperidine-4-carboxylic acid (4-isopropyl-phenyl)-amide; 1-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid (4-trifluoromethoxy-phenyl)-amide; 1-benzenesulfonyl-piperidine-4-carboxylic acid (4-trifluoromethoxy-phenyl)-amide; 1-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid (4-difluoromethoxy-phenyl)-amide; 1-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid (4-isopropyl-phenyl)-amide; 1-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid (4-chloro-2-fluoro-phenyl)-amide; 1-benzoyl-piperidine-4-carboxylic acid (4-isopropyl-phenyl)-amide; 1-(2-chloro-benzoyl)-piperidine-4-carboxylic acid (4-isopropyl-phenyl)-amide; 1-benzenesulfonyl-piperidine-4-carboxylic acid (1-phenyl-cyclopropylmethyl)-amide or 1-(toluene-4-sulfonyl)-piperidine-4-carboxylic acid (1-phenyl-cyclopentylmethyl)-amide.