Patent ID: 6248742
Filing Date: 2001-06-19
Classification: A61P,C07D

Abstract:
A method for treating oxidative stress selected from the group consisting of infections and inflammations comprising administering to a patient in need thereof an effective amount of a compound of the formula: ##STR9##wherein R.sub.1 represents hydrogen or from 1 to 4 substituents in positions 1-4 or positions 7-10, said substituents selected from the group consisting of halogen, C.sub.1 -C.sub.4 alkyl groups, C.sub.1 -C.sub.4 alkoxy groups, trifluoromethyl, and trichloromethyl, wherein in one of the positions 7-10 R.sub.1 represents a hydroxyl group;X is a group --(CH.sub.2).sub.n --R.sub.2, wherein R.sub.2 represents a nitrogen containing basic residue selected from the group consisting of NH.sub.2, NHR.sub.4 and NR.sub.5 R.sub.6, wherein R.sub.4, R.sub.5 and R.sub.6 independently are lower alkyl or cycloalkyl and n is an integer of from 1 to 4, R.sub.3 represents hydrogen, lower alkyl groups, lower cycloalkyl groups, and the physiologically acceptable addition products of the compounds with acids and halogen adducts.