Patent ID: 9193766
Filing Date: 2015-11-24
Classification: A61K,A61P,C07K,G01N,Y02A

Abstract:
1. An isolated polypeptide that binds specifically to β-site amyloid precursor protein cleaving enzyme 1 (BACE1), wherein the polypeptide comprises the amino acid sequence X1-S-X2-Y-C-R-L-X3-X4-X5-X6-C-(X7) n (SEQ ID NO: 6), wherein X2 is glutamic acid or aspartic acid; wherein X2 is methionine, leucine, isoleucine or valine; wherein X3 is leucine or methionine; wherein X4 is glycine, serine or alanine; wherein X5 is leucine, isoleucine or valine; wherein X6 is glycine or alanine; wherein X7 is glycine, aspartic acid or glutamic acid, and wherein n is 0 or 1.