Patent ID: 9164092
Filing Date: 2015-10-20
Classification: G01N

Abstract:
1. A method for the diagnosis of intra-amniotic inflammation or infection in a pregnant female mammalian subject comprising: (a) measuring in a sample of cervical-vaginal fluid obtained from said subject the levels of interleukin-6 (IL-6) and fetal fibronectin (fFN) relative to the corresponding levels of said proteins in normal cervical-vaginal fluid or cervical-vaginal fluid known to be indicative of intra-amniotic inflammation or infection; and (b) diagnosing said subject with intra-amniotic inflammation or infection if each of said levels of each of said proteins in said sample is determined to show a statistically significant difference relative to the corresponding levels of each of said proteins in said normal cervical-vaginal fluid, or is determined not to show a statistically significant difference relative to the corresponding levels of each of said proteins in said cervical-vaginal fluid known to be indicative of intra-amniotic inflammation or infection.