Patent ID: 8883191
Filing Date: 2014-11-11
Classification: A61K

Abstract:
1. A method for producing a dried film which disintegrates upon contact with saliva or water, said film comprising an inner phase of liposoluble liquid droplets of flavors and fragrances and a solid, water soluble outer phase containing at least 40% (w/v) polyvinyl alcohol, wherein both of said phases are water-free, said droplets being distributed within said water-free outer, solid, water-soluble phase, the size of said liquid droplets being in the range from 1 μm to 100 μm, said method comprising the steps of: a) dissolving a polyvinyl alcohol in water to obtain a polyvinyl alcohol solution; b) adjusting the temperature of the solution to below 40° C., and then generating said liquid droplets by adding, while stirring, at least one member of the group consisting of liposoluble flavors and fragrances in liquid form in an amount between 0.1 and 30 wt.-% relative to the water-free portion of the outer phase to the polyvinyl alcohol solution, and adjusting the size of the liquid droplets within the range of 1 μm to 100 μm by adding a surfactant to the outer phase, said surfactant being added at a concentration of up to 30%-wt. relative to the the outer phase, said solution becoming a liquid mass; c) coating said liquid mass onto a carrier; d) drying said liquid mass to obtain said dried film; and e) separating the film from said carrier; wherein said liposoluble flavors and fragrances are selected from the group consisting of ethereal oils and volatile odoriferous or flavoring substances having a limited miscibility with water.