Patent ID: 6689741
Filing Date: 2004-02-10
Classification: A61K,A61P,C08B,C08G

Abstract:
A biocompatible polymer of the following general formula (I):AaXxYyZz wherein:A represents a monomer based on glucose which is substituted with x, y, and z wherein, each x, y, and z are selected independently, and X represents a carboxyl group bonded to monomer A and is contained within a group according to the following formula: â€”Râ€”COOâ€”Râ€², in which R is a bond or an aliphatic hydrocarbon chain, optionally branched and/or unsaturated, and which can contain one or more aromatic rings except for benzylamine and benzylamine sulfonate, and Râ€² represents a hydrogen atom, Y, Z, or a cation, Y represents a sulfate of sulfonate group bonded to a monomer A and is contained within a group according to one of the following formulas: â€”Râ€”Oâ€”SO3â€”Râ€³, â€”Râ€”Nâ€”SO3â€”Râ€³, â€”Râ€”SO3â€”Râ€³, in which R is a bond or an aliphatic hydrocarbon chain, optionally branched and/or unsaturated, and which can contain one or more aromatic rings except for benzylamine and benzylamine sulfonate, and Râ€³ represents a hydrogen atom, Z, or a cation, Z is selected from the group consisting of amino acids, fatty acids, fatty alcohols, ceramides or derivatives thereof, and nucleotide addressing sequences, a represents the number of monomer A such that the mass of said polymers of formula (I) is greater than approximately 5,000 da, x represents a substitution rate of the monomers A by the groups X, which is between approximately 20 and 150%, and y represents a substitution rate of the monomers A by the groups Y, which is between approximately 30 and 150%, z represents the rate of substitution of monomers A by groups Z, which is between approximately 0 and 50%.