Patent ID: 7977380
Filing Date: 2011-07-12
Classification: A61P,C07D

Abstract:
1. A method of treating a disease or condition selected from the group consisting of retinopathy, proliferative retinopathy, neuropathy, increased blood pressure, brain edema, increased albumin excretion, macroalbuminuria and nephropathy, said method comprising administering to a subject in need thereof a pharmaceutically effective amount of a compound having formula (I): wherein Ar is a bond or an aromatic ring selected from the group consisting of benzene, pyridine and pyrimidine; the subscript m is an integer of from 0 to 5; each R L is a linking group selected from the group consisting of a bond, CH Q Y is a member selected from the group consisting of C and N; when Ar is a bond, m is 1; when Ar is an aromatic ring, m is an integer of from 0-5; and pharmaceutically acceptable salts thereof.