Patent ID: 8987414
Filing Date: 2015-03-24
Classification: A61P,C07K

Abstract:
1. A peptidomimetic macrocycle comprising an amino acid sequence which is at least 90% identical to an amino acid sequence of SEQ ID NO. 455, wherein the peptidomimetic macrocycle has the formula: an isomer or pharmaceutically acceptable salt thereof wherein: each A, C, D, and E is independently an amino acid; each B is independently an amino acid, [—NH-L 3 -CO—], [—NH-L 3 -SO 2 —], or [—NH-L 3 -]; each R each L and L′ is independently a macrocycle-forming linker of the formula each L each R each R each K is independently O, S, SO, SO each R each R each R each R v is an integer from 1-1000; w is an integer from 3-1000; u is an integer from 1-10; each x, y and z is independently an integer from 0-10; and n is an integer from 1-5.