Patent ID: 6083482
Filing Date: 2000-07-04
Classification: C07H,C12N

Abstract:
A compound having the formula I, ##STR15## wherein B is selected from a group comprising adenine, cytosine, guanine, hypoxanthine, uracil, thymine, a nucleoside base, or a modified nucleoside base;X and Y are independently selected from a group comprising O, S, CH.sub.2, C.dbd.O, C.dbd.S, C.dbd.CH.sub.2, CHF, CF.sub.2 ;Z is selected from N, CH;R.sub.2 is H, F, OH, or OMe;R.sub.1 and R.sub.3 are independently selected from H, OH, P(OR).sub.2, P(O)(OR).sub.2, P(S)(OR).sub.2, P(O)(SR)OR, acyl, carbobenzoxy, trifluoroacetyl, p-nitrophenyloxycarbonyl, or any suitable protecting group or an activating group for building oligomers, where R is H, 2-cyanoethyl, diisopropylamino, alkyl, alkenyl, alkynyl, or a hydrophobic masking group, where R can be same or different from each other in case of (OR).sub.2, (SR)OR.