Patent ID: 7959917
Filing Date: 2011-06-14
Classification: A61K,A61P,C07K,Y10S

Abstract:
1. An isolated antibody molecule specific for human immunoglobulin E, the antibody molecule comprising a set of CDRs: HCDR1, HCDR2, HCDR3, LCDR1, LCDR2 and LCDR3 in which: HCDR1 comprises the amino acid sequence of SEQ. ID. NO: 103; HCDR2 comprises the amino acid sequence of SEQ. ID. NO: 104; HCDR3 comprises the amino acid sequence of SEQ. ID. NO: 105; wherein SEQ. ID. NO: 105 may comprise one or more of the following substitutions: LCDR1 comprises the amino acid sequence of SEQ. ID. NO: 108; LCDR2 comprises the amino acid sequence of SEQ. ID. NO: 109; LCDR3 comprises the amino acid sequence of SEQ. ID. NO: 110, wherein SEQ. ID. NO: 110 may comprise one or more of the following substitutions: