Patent ID: 6291175
Filing Date: 2001-09-18
Classification: A61P,C12Q

Abstract:
A method for treating a patient at risk for or diagnosed with Alzheimer's disease, said method comprisingdetermining the genotype at nucleotide 1828 of the BCHE gene of said patient and predicting the efficacy of a therapy for treating said patient,wherein the detection of an adenine at position 1828 indicates a predisposition to non-responsiveness to cholinomimetic or vasopressinergic therapy and the detection of guanine homozygosity at position 1828 indicates a predisposition to responsiveness to cholinomimetic or vasopressinergic therapy, andwherein said therapy comprises administering a cholinomimetic or vasopressinergic therapy to patients having guanine homozygosity at position 1828 of the BCHE gene.