Patent ID: 9023997
Filing Date: 2015-05-05
Classification: A61K,A61P,C07K

Abstract:
1. An isolated antibody or an antigen binding fragment thereof that binds human immunoglobulin-like transcript 5 (ILT5) comprising: a heavy chain complementarity determining region 1 (VH CDR1) comprising the amino acid sequence of SEQ ID NO: 4; a heavy chain complementarity determining region 2 (VH CDR2) comprising the amino acid sequence of SEQ ID NO: 5; a heavy chain complementarity determining region 3 (VH CDR3) comprising the amino acid sequence of SEQ ID NO: 6; a light chain complementarity determining region 1 (VL CDR1) comprising the amino acid sequence of SEQ ID NO: 7; a light chain complementarity determining region 2 (VL CDR2) comprising the amino acid sequence of SEQ ID NO: 8; and a light chain complementarity determining region 3 (VL CDR3) comprising the amino acid sequence of SEQ ID NO: 9.