Patent ID: 8350052
Filing Date: 2013-01-08
Classification: C07D,C07F

Abstract:
1. A process for the preparation of 1-benzyl-3-hydroxymethyl-1H-indazole represented by the following formula (I): in which R R R R R R in which a) 1-benzyl-3-hydroxymethyl-1H-indazole represented by the following formula (II): is caused to react with a hydrohalogen acid of formula HX″, where X″ is a halogen atom selected from the group consisting of chlorine, bromine and iodine, to form 1-benzyl-3-halogenomethyl-1H-indazole represented by the following formula (V): b) 1-benzyl-3-halogenomethyl-1H-indazole represented by the abovementioned formula (V) is caused to react in the presence of a strong base with a compound represented by the following formula (VI): to form the 1-benzyl-3-hydroxymethyl-1H-indazole represented by the abovementioned formula (I).