Patent ID: 6706905
Filing Date: 2004-03-16
Classification: C07F

Abstract:
A method for producing a palladium-complex compound represented by the general formula (4), said method comprising:(a) reacting an aromatic compound represented by the general formula (1), with a palladium (II) compound and a phosphine derivative, in the presence of a first basic substance, thereby obtaining a palladium-complex compound represented by the general formula (2); and (b) reacting said palladium-complex compound represented by the general formula (2) with a benzoic acid represented by the general formula (3), in the presence of a second basic substance, thereby producing a palladium-complex compound represented by the general formula (4), Ar1Xâ€ƒâ€ƒ(1) â€ƒwhere Ar1 is a phenyl group having at least one substituent selected from the group consisting of a trifluoromethyl group, a trifluoromethoxy group, a halogen, a nitro group, an acetyl group, a cyano group, an alkyl group having 1-4 carbon atoms, an alkoxyl group having 1-4 carbon atoms, and an alkoxycarbonyl group having 2-5 carbon atoms; and X is a halogen, trifluoromethanesulfonate group, an alkylsulfonate group having a carbon atom number of 1-4, or an arylsulfonate group, Ar1â€”PdL2Xâ€ƒâ€ƒ(2) â€ƒwhere each L is triphenylphosphine, and Ar1 and X are defined as above, Ar2â€”COOHâ€ƒâ€ƒ(3) â€ƒwhere Ar2 is a phenyl group having at least one substituent selected from the group consisting of a trifluoromethyl group, a trifluoromethoxy group, a halogen, a nitro group, an acetyl group, a cyano group, an alkyl group having 1-4 carbon atoms, an alkoxyl group having 1-4 carbon atoms, and an alkoxycarbonyl group having 2-5 carbon atoms, â€ƒwhere Ar1, Ar2, and L are defined as above.