Patent ID: 8841237
Filing Date: 2014-09-23
Classification: C12Q

Abstract:
1. A method for assaying a binding of a mammalian transcription factor comprising a step of interacting a sample capable of comprising the transcription factor with the transcription chip wherein the transcription chip comprises: at least one polynucleotide comprising one or more element sequences to which a mammalian transcription factor can be bound is immobilized on a substrate; wherein the one or more element sequences is selected from the group consisting of GGAATTTCCC (SEQ ID NO. 23) and GGGAAATTCC (SEQ ID NO. 24); GGGGATCCC and GGGATCCCC; TGACTCAT and ATGAGTCA; AGGTCA and TGACCT; AGGTCA and TGACCT; AGGTCA and TGACCT; AGGTCATGACCT (SEQ ID NO. 25); AGAACA and TGTTCT; TGACGTCA; wherein said polynucleotide has a partial sequence of a promoter; wherein said substrate is made by forming a diamond thin film on a support; wherein said polynucleotide is bound to the diamond thin film through an optionally appropriate spacer; and detecting the transcription factor bound to the transcription chip.