Patent ID: 6835811
Filing Date: 2004-12-28
Classification: A61K

Abstract:
A method for extended storage of reduced glutathione in solution, comprising the steps of:a) dissolving a predetermined quantity of reduced glutathione in an aqueous medium having a pH of between 5.0 and 8.0 to produce a reduced glutathione solution having a predetermined initial concentration [A]o, wherein, when the ratio [A]/[A]o, where [A] is the actual glutathione concentration at time t, is plotted as a function of time t, the concentration of reduced glutathione decreases over time in a linear fashion with a temperature-dependent slope; and b) storing the reduced glutathione solution at a predetermined temperature which is above the freezing point of the solution and below 15Â° C., so as to maintain the rate of reduced glutathione decay at between 0% and 5% of the predetermined initial concentration per month, where the initial concentration of reduced glutathione is between 10 mg/ml and 400 mg/ml.