Patent ID: 7470677
Filing Date: 2008-12-30
Classification: A61K

Abstract:
1. A method of protecting cells from oxidant-induced toxicity comprising contacting said cells with a non-toxic amount of a scavenger of the formula, or a pharmaceutically acceptable salt thereof, or metal complex thereof, sufficient to effect said protection; wherein: said metal is selected from the group consisting of manganese, copper and iron, each R 1 ′ is independently a bond, wherein Y″ is an alkyl group, and indicates bonding to R 2 ′ at any position and indicates bonding to R 2 ′ and the R 1 ′ phenyl substituent at any position; each R each R with the proviso that when R R 3 ′ is not —COOH, —COY″ or —COO − , when R R 3 ′ is not —NO 2 , —R