Patent ID: 6727377
Filing Date: 2004-04-27
Classification: B01J,C07B,C07C,C07F

Abstract:
A catalyst comprising a chiral compound in the form of a complex with a transition metal wherein said compound is represented by the formula B, Bâ€², D, Dâ€² or the corresponding enantiomers: wherein:a) R and R2 are independently aryl, alkyl, alkyl aryl, aryl alkyl, or chiral oxazolino which may be substituted with carboxylic acid, alkoxy, hydroxy, alkylthio, thiol or dialkylamino groups; b) the ring component represents a protected diol, a crown ether linkage, â€”O-alkyl-Oâ€” wherein the alkyl group is linked to a polymer, or â€”Oâ€”(CH2CH2â€”O)nâ€” wherein n is an integer ranging from 1 to 8 and the methylene groups are optionally substituted by C1-C8 alkyl;c) in formulas B and Bâ€², the â€ƒmay be: â€”(CH2)nâ€” where n is an integer ranging from 1 to 8; â€”(CH2)nX(CH2)m â€” wherein n and m are each integers, the same or different, ranging from 1 to 8, and X is O, S, NR4, PR4, AsR4, SbR4, divalent aryl, divalent fused aryl, divalent 5-membered ring heterocyclic group, or divalent fused heterocyclic group, wherein R4 is aryl, alkyl, substituted aryl, or substituted alkyl; or 1,2-divalent phenyl, 2,2â€²-divalent 1,1â€²biphenyl or 2,2â€²-divalent 1,2â€²-binapthyl or ferrocene, each of which may be substituted with aryl, C1-C8 alkyl, F, Cl, Br, I, COOR5, SO3R5, PO3R52, OR5, SR5, NR52, PR52, AsR52, or SbR52; wherein the substitution on 1,2-divalent phenyl, the ferrocene or biaryl bridge can be independently halogen, alkyl, alkoxyl, aryl, aryloxy, nitro, amino, vinyl, substituted vinyl, alkynyl, or sulfonic acids; and R5 is C1-C8 alkyl, C1-C8 fluoroalkyl, or C1-C8 perfluoroalkyl, aryl; substituted aryl; arylalkyl; ring-substituted arylalkyl; or â€”CR32(CR32)qX(CR32)pR1 wherein q and p are integers, the same or different, ranging from 1 to 8; R3 is aryl, alkyl, substituted aryl, or substituted alkyl; and X is as defined above.