Patent ID: 6524578
Filing Date: 2003-02-25
Classification: A61K,A61Q

Abstract:
A method for reducing wrinkles and discoloration in humans which comprises the step of applying to human tissue skin cells an effective amount of a nuclease solution, said nuclease solution comprised of:(a) water; (b) an amount of nuclease equal to from about 1 Kunitz unit per millimeter of water to about 70 Kunitz units per milliliter of water, and (c) a co-factor capable of activating the nuclease, wherein said nuclease solution is applied on a subject's skin in an amount equal to from about 0.01 milliliters of said nuclease solution per 1 square centimeter of skin to about 1 milliliter of said nuclease solution per 1 centimeter of skin, and wherein after application of said nuclease solution wrinkles and discolorations are reduced in humans.