Patent ID: 6118018
Filing Date: 2000-09-12
Classification: C07B,C07C

Abstract:
A method of adding 1 to 4 chlorine or bromine atoms to the aromatic ring of a compound having the general formula ##STR2## comprising reacting said compound with a chlorinating agent or a brominating agent in the presence of about 0.1 to about 10 mole % of a Lewis acid catalyst and about 0.001 to about 0.1 equivalents of an iodine-containing cocatalyst selected from the group consisting of inorganic iodides and alkyl iodides containing 1 to 18 carbon atoms at a temperature of ambient to about 100.degree. C. and atmospheric pressure, where each R' is an electron-withdrawing group independently selected from carboxylate, keto,trihalomethyl, and nitrilo, each R"" is independently selected from R and OR, R is alkyl from C.sub.1 to C.sub.18, m is 1 or 2, and n is 0 to 5-m.