Patent ID: 6689566
Filing Date: 2004-02-10
Classification: C07K,G01N,Y10S

Abstract:
â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒSEQUENCEâ€ƒLISTING  <160>â€ƒNUMBERâ€ƒOFâ€ƒSEQâ€ƒIDâ€ƒNOS:â€ƒ6 <210>â€ƒSEQâ€ƒIDâ€ƒNOâ€ƒ1<211>â€ƒLENGTH:â€ƒ7<212>â€ƒTYPE:â€ƒPRT<213>â€ƒORGANISM:â€ƒHomoâ€ƒsapiens <400>â€ƒSEQUENCE:â€ƒ1 Serâ€ƒValâ€ƒSerâ€ƒGluâ€ƒIleâ€ƒGlnâ€ƒLeu1â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ5  <210>â€ƒSEQâ€ƒIDâ€ƒNOâ€ƒ2<211>â€ƒLENGTH:â€ƒ84<212>â€ƒTYPE:â€ƒPRT<213>â€ƒORGANISM:â€ƒHomoâ€ƒsapiens <400>â€ƒSEQUENCE:â€ƒ2 Serâ€ƒValâ€ƒSerâ€ƒGluâ€ƒIleâ€ƒGlnâ€ƒLeuâ€ƒMetâ€ƒHisâ€ƒAsnâ€ƒL #euâ€ƒGlyâ€ƒLysâ€ƒHisâ€ƒLeuâ€ƒAsnâ€ƒ1â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ5â€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ10â€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ15 Serâ€ƒMetâ€ƒGluâ€ƒArgâ€ƒValâ€ƒGluâ€ƒTrpâ€ƒLeuâ€ƒArgâ€ƒLysâ€ƒL #ysâ€ƒLeuâ€ƒGlnâ€ƒAspâ€ƒValâ€ƒHisâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ20â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ25â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ30 Asnâ€ƒPheâ€ƒValâ€ƒAlaâ€ƒLeuâ€ƒGlyâ€ƒAlaâ€ƒProâ€ƒLeuâ€ƒAlaâ€ƒP #roâ€ƒArgâ€ƒAspâ€ƒAlaâ€ƒGlyâ€ƒSerâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ35â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ40â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ45 Glnâ€ƒArgâ€ƒProâ€ƒArgâ€ƒLysâ€ƒLysâ€ƒGluâ€ƒAspâ€ƒAsnâ€ƒValâ€ƒL #euâ€ƒValâ€ƒGluâ€ƒSerâ€ƒHisâ€ƒGluâ€ƒâ€ƒâ€ƒâ€ƒ50â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒ55â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒ60 Lysâ€ƒSerâ€ƒLeuâ€ƒGlyâ€ƒGluâ€ƒAlaâ€ƒAsnâ€ƒLysâ€ƒAlaâ€ƒAspâ€ƒV #alâ€ƒAsnâ€ƒValâ€ƒLeuâ€ƒThrâ€ƒLys65â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#70â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#75â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#80 Alaâ€ƒLysâ€ƒSerâ€ƒGln  <210>â€ƒSEQâ€ƒIDâ€ƒNOâ€ƒ3<211>â€ƒLENGTH:â€ƒ7<212>â€ƒTYPE:â€ƒPRT<213>â€ƒORGANISM:â€ƒHomoâ€ƒsapiens <400>â€ƒSEQUENCE:â€ƒ3 Valâ€ƒSerâ€ƒGluâ€ƒIleâ€ƒGlnâ€ƒLeuâ€ƒMet1â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ5  <210>â€ƒSEQâ€ƒIDâ€ƒNOâ€ƒ4<211>â€ƒLENGTH:â€ƒ8<212>â€ƒTYPE:â€ƒPRT<213>â€ƒORGANISM:â€ƒRat <400>â€ƒSEQUENCE:â€ƒ4 Serâ€ƒValâ€ƒSerâ€ƒGluâ€ƒIleâ€ƒGlnâ€ƒLeuâ€ƒMet1â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ5  <210>â€ƒSEQâ€ƒIDâ€ƒNOâ€ƒ5<211>â€ƒLENGTH:â€ƒ8<212>â€ƒTYPE:â€ƒPRT<213>â€ƒORGANISM:â€ƒRat <400>â€ƒSEQUENCE:â€ƒ5 Alaâ€ƒValâ€ƒSerâ€ƒGluâ€ƒIleâ€ƒGlnâ€ƒLeuâ€ƒMet1â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ5  <210>â€ƒSEQâ€ƒIDâ€ƒNOâ€ƒ6<211>â€ƒLENGTH:â€ƒ78<212>â€ƒTYPE:â€ƒPRT<213>â€ƒORGANISM:â€ƒHomoâ€ƒsapiens <400>â€ƒSEQUENCE:â€ƒ6 Leuâ€ƒMetâ€ƒHisâ€ƒAsnâ€ƒLeuâ€ƒGlyâ€ƒLysâ€ƒHisâ€ƒLeuâ€ƒAsnâ€ƒS #erâ€ƒMetâ€ƒGluâ€ƒArgâ€ƒValâ€ƒGluâ€ƒ1â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ5â€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ10â€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ15 Trpâ€ƒLeuâ€ƒArgâ€ƒLysâ€ƒLysâ€ƒLeuâ€ƒGlnâ€ƒAspâ€ƒValâ€ƒHisâ€ƒA #snâ€ƒPheâ€ƒValâ€ƒAlaâ€ƒLeuâ€ƒGlyâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ20â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ25â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ30 Alaâ€ƒProâ€ƒLeuâ€ƒAlaâ€ƒProâ€ƒArgâ€ƒAspâ€ƒAlaâ€ƒGlyâ€ƒSerâ€ƒG #lnâ€ƒArgâ€ƒProâ€ƒArgâ€ƒLysâ€ƒLysâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ35â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ40â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ45 Gluâ€ƒAspâ€ƒAsnâ€ƒValâ€ƒLeuâ€ƒValâ€ƒGluâ€ƒSerâ€ƒHisâ€ƒGluâ€ƒL #ysâ€ƒSerâ€ƒLeuâ€ƒGlyâ€ƒGluâ€ƒAlaâ€ƒâ€ƒâ€ƒâ€ƒ50â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒ55â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#â€ƒâ€ƒâ€ƒâ€ƒ60 Asnâ€ƒLysâ€ƒAlaâ€ƒAspâ€ƒValâ€ƒAsnâ€ƒValâ€ƒLeuâ€ƒThrâ€ƒLysâ€ƒA #laâ€ƒLysâ€ƒSerâ€ƒGln65â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#70â€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒâ€ƒ#751. A substantially pure antibody or antibody fragment specific for an initial peptide sequence of whole parathyroid hormone wherein said initial peptide sequence consists of VAL-SER-GLU-ILE-GLN-LEU-MET (SEQ ID NO:3), and wherein at least four amino acids in said initial peptide sequence are part of a reactive portion with said antibody.