Patent ID: 6365343
Filing Date: 2002-04-02
Classification: A61K,A61P

Abstract:
A method of treating rhinovirus infection in a warm-blooded animal comprising using an insufflate for nasal administration and wherein the drug in such insufflate is soluble intercellular adhesion molecule, type I (sICAM-1), the improvement which comprises using as the insufflate a dry, powdered pharmaceutical composition comprising:(a) sICAM-1 is an amount of about 0.07 to about 7% by weight; (b) a bulking agent selected from the group consisting of amino acids, sugar alcohols and carbohydrate based polymers, in an amount of about 70% to about 90% by weight; and (c) carboxymethyl cellulose, Na, in an amount of about 14% to about 45% by weight, where the dry, powdered pharmaceutical composition is sequentially passed through U.S. standard sieves #18 and #35.