Patent ID: 9011878
Filing Date: 2015-04-21
Classification: A61K,A61P,C12Q,G01N

Abstract:
1. A vaccine composition for vaccinating an animal against B. hyodysenteriae infection comprising a non-naturally occurring live strain of B. hyodysenteriae and a pharmaceutically acceptable vehicle, wherein: (a) said strain has been cured of a plasmid which contained orf 11-16 (SEQ ID NOS:1 to 6); or (b) said orf 11-16 (SEQ ID NOS:1 to 6), has been deleted or disrupted in said strain so that no functional product is transcribed or translated from the sequences encoded by said orf 11-16 (SEQ ID NOS:1 to 6); and wherein said strain has reduced virulence, with the proviso that the strain is not