Patent ID: 6046329
Filing Date: 2000-04-04
Classification: A61P,C07D

Abstract:
A compound of the formula I ##STR6## in which R1 is 1-4C-alkyl,R2 is 1-4C-alkyl,R3 is hydrogen (H), 1-7C-alkyl,3-7C-alkenyl, 1-4C-alkoxy, halogen, halo-1-4C-alkyl, cyano-1-4C-alkyl, 1-4C-alkoxycarbonyl, nitro, hydroxyiminomethyl, methoxyiminomethyl or a group --CH.sub.2 --RI, in which RI is the radical bonded to the substituent R3 in formula I,A is a straight-chain or branched 1-5C-alkylene radical,Ar is a phenyl radical substituted by R4, R5 and R6, in whichR4 is hydrogen, halogen, nitro, trifluoromethyl, hydroxyl, 1-4C-alkoxy, completely or partly fluorine-substituted 1-4C-alkoxy, amino or 1-4C-alkylcarbonylamino,R5 is hydrogen, halogen or 1-4C-alkoxy andR6 is hydrogen or 1-4C-alkoxy, or in whichR4 and R5 are ortho to one another and together are a 1-hydroxymethylethylenedioxy radical [--O--CH(CH.sub.2 OH)--CH.sub.2 --O--] andR6 is hydrogen,X is the group NH or CO--NH,Y is sulfur (S) andZ is CO,or a salt thereof.