Patent ID: 8845965
Filing Date: 2014-09-30
Classification: G01N,Y10T

Abstract:
1. A sensor for use in detecting an analyte in a sample, the sensor comprising: a source of electromagnetic radiation configured to generate a series of pulses of electromagnetic radiation; a transducer including a pyroelectric or piezoelectric polymer substrate and a transparent electrode layer on a surface of the substrate, wherein the transducer is configured to convert energy generated by a label that undergoes non-radiative decay after absorbing the electromagnetic radiation into an electrical signal; a layer of parylene on the transparent electrode layer; a reagent immobilised on the transducer, the reagent having a binding site which is capable of binding the analyte or a derivative of the analyte; a layer of protein between the parylene layer and the immobilised reagent, wherein the protein is adsorbed directly on the parylene layer by non-covalent interactions; and a detector for detecting the electrical signal from the transducer.