Patent ID: 6300344
Filing Date: 2001-10-09
Classification: A61P,C07D

Abstract:
A compound of the formula: ##STR28##whereinR.sup.1 is carboxy or protected carboxy,R.sup.2 is aryl which may have suitable substituent(s),R.sup.3 is aryl which may have suitable substituent(s),R.sup.4 is hydrogen, lower alkyl, hydroxy or aryl,A.sup.1 is lower alkylene, ##STR29## ##STR30##(in which --A.sup.4 -- is bond, --CH.sub.2 -- or --CO--, and ##STR31##is cyclo(C.sub.5 -C.sub.8)alkene, cyclo(C.sub.7 -C.sub.8)alkane, bicycloheptane, bicycloheptene, tetrahydrofuran, tetrahydrothiophene, azetidine, pyrrolidine or piperidine, each of which may have suitable substituent(s)) or --X--A.sup.6 -- [in which --X-- is --O--, --S-- or ##STR32##(in which R.sup.5 is hydrogen, lower alkyl or acyl) andA.sup.6 is lower alkylene which may have suitable substituent(s)], andn is 0 or 1, and a pharmaceutically acceptable salt thereof.