Patent ID: 8835399
Filing Date: 2014-09-16
Classification: A61P,C07K,C12N,C12Y

Abstract:
1. A method for producing photoactive fusion proteins having a desired activity controllable by far-red and/or near-infrared (NIR) light, said method comprising the steps: a. designing one or more homodimeric fusion proteins, each comprising a photoreceptor protein module and a heterologous output module, wherein: b. producing a plurality of DNA molecules, each encoding a said monomer of a said homodimeric fusion protein that has at least one unique fusion site; c. screening said DNA molecules for their ability to produce homodimeric photoactive fusion proteins capable of performing said desired activity by a method comprising: wherein the level of said desired activity of said fusion proteins is controllable by NIR light when the level of said desired activity is changed by the presence and/or absence of MR light having said selected wavelengths.