Patent ID: 8859622
Filing Date: 2014-10-14
Classification: A61K,A61P,C07D

Abstract:
1. A method of administering an amine-containing pharmaceutically active compound formulation comprising: a) providing said amine-containing pharmaceutically active compound formulation by preparing an organic acid salt of said compound wherein said organic acid addition salt exhibits sustained release of said compound from said organic acid salt wherein said organic acid salt of said compound is selected from the group consisting of: ephedrine pamoate characterized by a method selected from the group consisting of: pseudoephedrine pamoate characterized by a method selected from the group consisting of: benzphetamine pamoate characterized by a method selected from the group consisting of: phentermine pamoate characterized by a method selected from the group consisting of: b) preparing an oral dose formulation comprising said organic acid salt of said compound and a matrix; c) administering said oral dose formulation to a patient for oral ingestion of said oral dose by said patient; and d) wherein upon use of said organic salt of said compound absent said matrix by said patient via a mucosal membrane other than gastrointestinal mucosal membranes said amine-containing pharmaceutically active compound is not bio-available.