Patent ID: 8835635
Filing Date: 2014-09-16
Classification: A61K,C07D

Abstract:
1. An amorphous co-precipitate comprising vilazodone hydrochloride and a pharmaceutically acceptable excipient, wherein the pharmaceutically acceptable excipient is selected from the group consisting of polyvinylpyrrolidone, hydroxypropyl cellulose, hydroxypropyl methylcellulose and hypromellose phthalate, wherein the amorphous co-precipitate is: a) the amorphous co-precipitate of vilazodone hydrochloride with polyvinylpyrrolidone in a ratio of 1:10 which is characterized by a powder XRD pattern, showing no well-defined peaks, substantially in accordance with b) the amorphous co-precipitate of vilazodone hydrochloride with polyvinylpyrrolidone in a ratio of 1:5 which is characterized by a powder XRD pattern, showing no well-defined peaks, substantially in accordance with c) the amorphous co-precipitate of vilazodone hydrochloride with hypromellose phthalate in a ratio of 1:10 which is characterized by a powder XRD pattern, showing no well-defined peaks, substantially in accordance with d) the amorphous co-precipitate of vilazodone hydrochloride with hydroxypropyl cellulose is characterized by a powder XRD pattern, showing no well-defined peaks, substantially in accordance with