Patent ID: 8735378
Filing Date: 2014-05-27
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A method of treating inflammation that is associated with a metabolic disorder selected from the group consisting of Type II diabetes, insulin resistance, atherosclerosis, dyslipidemia, retinopathy associated with diabetic complications, nephropathy associated with diabetic complications, neuropathy associated with diabetic complications, and macular edema associated with diabetic complications, comprising administering to a patient in need thereof an effective amount of a compound of Formula III: or a pharmaceutically acceptable salt, enantiomer, or stereoisomer thereof, wherein W each a and c are independently H, CH each b is H, CH each d is H or C(O)OH; each n, o, p, and q is independently 0 or 1; each Z is H or with the proviso that there is at least one each r is independently 2, 3, or 7; each s is independently 3, 5, or 6; each t is independently 0 or 1; u is 0 or 1; with the proviso that when r is 7, s is 3; Q is null, C(O)CH e is H or any one of the side chains of the naturally occurring amino acids; W R is H or C T is H, C(O)CH