Patent ID: 6545095
Filing Date: 2003-04-08
Classification: A61K,A61Q,C08F

Abstract:
A process for preparing a microgel composition comprising:(i) providing a living prepolymer comprising a linear prepolymer and a radical-terminating group adapted to reversibly cleave from the linear prepolymer under activating conditions to provide a reactive linear prepolymer radical wherein the linear prepolymer portion of the living prepolymer comprises a polymeric chain of at least 5 monomer units; and (ii) polymerizing the living prepolymer under activating conditions with a monomer composition comprising a multi-olefinic cross-linking monomer to provide microgel particles comprising a cross-linked polymer core formed from the monomer composition and a multiplicity of linear arms appended to the core said arms being formed from the linear polymer portion of said living prepolymer.