Patent ID: 6573296
Filing Date: 2003-06-03
Classification: A01N,A61K,C07D

Abstract:
A therapeutic composition comprising a compound represented by the formula: wherein R1 represents hydrogen, oxygen, alkyl, alkenyl, acyl, aryl, halogen, sulfo, nitro, carboxyl, hydroxyl, hydroxyalkyl, alkoxy, or other water soluble side chain, and Y is a side chain comprising lipids, nucleic acids, derivatized polymeric substances which have from 1 to about 1,000 monomeric units and which enhance the impermeance of said compound, immunoglobulins, growth hormones, insulin, interferons, plasma albumin, fibrinogen, plasminogen activator, heparin, chondroitin, sulfate, soybean trypsin inhibitor, L-asparaginase, and ribonuclease, wherein any of the foregoing optionally is attached to the C-15 carbon by an ether, ester, carbonyl, or glycosidic linkage and a pharmaceutically effective carrier therefor, with the proviso that said compound is not glaucarubinone, castelanone, soularubinone, or simalikalactone D.