Patent ID: 8450290
Filing Date: 2013-05-28
Classification: A61K,A61P,C12N

Abstract:
1. A method for treating prostate cancer in a mammal, comprising the steps of: administering to a mammal in need of treatment for prostate cancer in amounts therapeutically effective in combination, (a) an antisense oligomer comprising: wherein uppercase letters denote beta-D-oxy-LNA monomers and lowercase letters denote DNA monomers, the subscript “s” denotes a phosphorothioate linkage, and Me C denotes a beta-D-oxy-LNA monomer containing a 5-methylcytosine base, or a conjugate of said oligomer, or a pharmaceutically acceptable salt of said compound or said conjugate; and (b) the compound bicalutamide, or a pharmaceutically acceptable salt thereof.