Patent ID: 8859786
Filing Date: 2014-10-14
Classification: C07C,C07D

Abstract:
1. A method (B) for the preparation of a compound of formula (II); R1 is Cl, Br or CN; method (B) comprises a step (C) and a step (B); step (B) is done after step (C); step (C) comprises a reaction (C) of a compound of formula (VI) with a compound (C) to provide a compound of formula (IV); the compound (C) is selected from the group consisting of Cl step (B) comprises a reaction (B) of the compound of formula (IV), which has been prepared in step (C), with a compound of formula (V) in the presence of a base (B); R1-IV and R3 are identical and are Cl or Br; base (B) is selected from the group consisting of N(R4)(R6)R6, 1,4-diazabicyclo[2.2.2]octane, 1,8-diazabicyclo[5.4.0]undec-7-ene, pyridine, pyridine substituted with 1 or 2 independently selected identical or different C R4, R5, R6 are identical or different and independently from each other selected from the group consisting of H, C R12 and R13 are identical or different and independently from each other H or C m is 2, 3, 4, 5 or 6; R16 and R17 are identical or different and independently from each other selected from the group consisting of H, methyl and ethyl; with the proviso, that if R1 in formula (II) is CN, then R9, R10 and R11 are identical or different and independently from each other selected from the group consisting of C