Patent ID: 8927773
Filing Date: 2015-01-06
Classification: C07C,C07D

Abstract:
1. A process for preparing a primary amine, the process comprising: i) preparing a solution of a secondary alcohol and a homogeneous catalyst in a fluid, nongaseous phase; ii) contacting the solution with free ammonia, at least one ammonia-releasing compound, or both, in an amount such that a molar ratio of the ammonia to hydroxyl groups in the secondary alcohol is at least 5:1; iii) reacting the ammonia with the secondary alcohol under a pressure of 5 to 500 bar to maintain a two phase reaction comprising a liquid phase and a gas phase to obtain the primary amine; and iv) optionally isolating the primary amine obtained; wherein: a volume ratio of the liquid phase to the gas phase in the reaction is greater than or equal to 0.25.