Patent ID: 7655408
Filing Date: 2010-02-02
Classification: A01K,A61P,C07H,C07K,C12Q,G01N

Abstract:
1. A method of determining the malignancy status of prostate cells contained in a sample undergoing testing, said method comprising: (a) amplifying a first PCA3 nucleic acid across nucleotide positions 26 and 255 of SEQ ID NO:1 and a second PCA3 nucleic acid across nucleotide positions 26 and 27 of SEQ ID NO:2 from mRNAs obtained from prostate cells contained in said sample if such first and/or second nucleic acids are present, whereby said first and second PCA3 nucleic acids are synthesized in relative abundance dependent on the malignant and non-malignant status of the prostate cells, (b)