Patent ID: 8843356
Filing Date: 2014-09-23
Classification: C12Q,G16B

Abstract:
1. A method of identifying a molecular target for a second trait in a second species, the method comprising: (a) identifying a first gene in a segregating population that is causal for a first trait exhibited by all or a portion of said segregating population, wherein each member of said segregating population is a member of a first species and wherein said second trait in said second species corresponds to said first trait in said first species, comprising: (b) obtaining a biological sample from members of said second species and mapping said first gene in said first species to a corresponding locus in the genome of the second species; and (c) determining whether a marker or a haplotype in said corresponding locus in the genome of the second species associates with said second trait, wherein, when said marker or said haplotype associates with said second trait in said second species, said locus is identified as said molecular target for said second trait, wherein steps (a) and (b) are performed by a suitably programmed computer having a computer program comprising a clustering module for clustering eQTL data from a plurality of eQTL analysis to form a eQTL locus interaction map and an analysis module for analyzing said eQTL interaction map to identify a locus in the genome of the second species that is associated with the second trait that corresponds to the first trait exhibited by the first species.