Patent ID: 6132286
Filing Date: 2000-10-17
Classification: C07D

Abstract:
A process for the preparation of 1,2,5,6-tetrahydro-3-carboalkoxypyridines of formula (III) ##STR4## wherein R is a straight or cyclic substituted or unsubstituted alkyl chain having 1 to 6 carbon atoms, phenyl C.sub.1-6 alkyl, menthol or a derivative of menthol, or a derivative of camphor, and R' is an alkyl chain having 1 to 4 carbon atoms or phenyl C.sub.1-6 alkyl comprising reacting an alkyl pyridinium salt of formula (II) ##STR5## wherein R and R' are as defined above and X is a suitable leaving group with sodium triacetoxyborohydride in the presence of an acid.