Patent ID: 7799545
Filing Date: 2010-09-21
Classification: C12N,C12P,C12Y

Abstract:
1. A host microbial organism transformed with a nucleic acid encoding an adipyl-coenzyme A (adipyl-CoA) biosynthetic pathway and a 6-aminocaproic acid biosynthetic pathway, which comprises exogenous nucleic acids encoding 6-aminocaproic acid biosynthetic pathway enzymes expressed in a sufficient amount to produce 6-aminocaproic acid, said 6-aminocaproic acid biosynthetic pathway enzymes comprising CoA-dependent aldehyde dehydrogenase; and transaminase, said transaminase classified as EC 2.6.1 and converting adipate semialdehyde to 6-aminocaproic acid, or 6-aminocaproate dehydrogenase.