Patent ID: 6417403
Filing Date: 2002-07-09
Classification: C07C

Abstract:
A process for preparing chiral (S)-2,3-disubstituted-1-propylamine derivatives expressed in the following formula 1, characterized in that a carbonyl group of chiral (S)-3,4-disubstituted-1-butanecarbonyl derivatives expressed in the following formula 2 is converted to an amine group: wherein,R1 represents hydrochloric acid salt (Hâ€”HCl), sulfuric acid salt (Hâ€”H2SO4) or â€”C(O)OR2; R2 represents linear or branched alkyl chain having carbon atoms of 1-10, benzyl or phenyl group; X and Y which are same or different, represents a halogen atom, hydroxy group, acetate group, sulfonate group, or in which X and Y are combined to form epoxy group, acetonide group; and Z represents NH2, NHNH2 or hydroxy group.