Patent ID: 8445024
Filing Date: 2013-05-21
Classification: A61K,A61Q,C08G,C08J,C08K

Abstract:
1. A preparation comprising at least one low molecular weight substance having a molar mass of from 15 g/mol to 1000 g/mol and at least one hyperbranched polymer, wherein said hyperbranched polymer comprises: a) a hydrophilic core having polyester units and hydrophobic end groups; b) a molecular weight greater than or equal to 6000 g/mol and a hydroxyl number in the range of from 0 to 200 mg KOH/g; c) a degree of branching in the range of from 20 to 70%; and d) a melting point of at least 30° C.; and wherein said preparation is in the form of particles having a size in the range of from 1 to 1000 μm and in which said low molecular substance is embedded in a shell which comprises said hyperbranched polymer, said preparation being made by a process comprising: (i) preparing a polymer melt comprising at least one hyperbranched polymer and at least one low molecular weight substance; (ii) introducing said polymer melt into a second liquid phase in which said hyperbranched polymer is sparingly soluble and which has a solidification temperature below the solidification temperature of said hyperbranched polymer, said second liquid phase comprising 60 to 100% by weight of water, alcohols having up to 4 carbon atoms or combinations thereof; (iii) dispersing said polymer melt in said second liquid phase at a temperature which is greater than or equal to the solidification temperature of said hyperbranched polymer; and (iv) solidifying said polymer melt dispersed in said second liquid phase.