Patent ID: 6124087
Filing Date: 2000-09-26
Classification: G01N

Abstract:
A method of diagnosing carcinoma corporis uteri or its precursor stage comprising the steps of:a) providing two blood samples of a patient, one comprising at least one of arterial and capillary blood (index A) and the other comprising venous blood (index V);b) measuring, in increments of 1 .mu.m, blood cells in the size range of i=6 .mu.m diameter to i=16 .mu.m diameter, and determining the number of cells that fall within said range in index A and also in index V to the total number of cells in index A and index V to obtain a percentage part value (N.sub.i) for each index;c) multiplying the obtained blood cell percentage part values by a weighting factor .alpha..sub.i, wherein .alpha..sub.i is 2.sup.10 for i=6 .mu.m, 2.sup.9 for i=7 .mu.m, 2.sup.8 for i=8 .mu.m, 2.sup.7 for i=9 .mu.m, 2.sup.6 for i=10 .mu.m, 2.sup.5 for i=9 .mu.m, 2.sup.4 for i=12 .mu.m, 2.sup.3 for i=13 .mu.m, 2.sup.2 for i=14 .mu.m, 2.sup.1 for i=15 .mu.m and 2.sup.0 for i=16 .mu.m;d) then calculating sums for each index by:A=.SIGMA. .alpha..sub.i *(N.sub.i).sup.AV=.SIGMA. .alpha..sub.i *(N.sub.i).sup.Ve) calculating values X=A+V and Y=A-V, andf) comparing the calculated X and Y values to value ranges obtained from healthy controls, precursor stage controls, and carcinoma controls, wherein, carcinoma corporis uteri are indicated if the calculated values fall within the range determined for carcinoma controls, precursor stage carcinoma corporis uteri are indicated if the calculated values fall within the range determined for precursor controls, and absence of a carcinoma is indicated if the calculated values fall within the range determined for healthy controls.