Patent ID: 6673822
Filing Date: 2004-01-06
Classification: A61K,C07K

Abstract:
A compound represented by the formula: or a pharmaceutically acceptable salt, or ester thereof, wherein R1 represents alkyl of 3-4 carbon atoms, alkenyl of 2-5 carbon atoms, alkynyl of 2-3 carbon atoms, imidazolylmethyl, â€”CH2CONH2, â€”CH2S(O)2NH2, â€”CH2SCH3, â€”CH2S(O)2CH3, â€”C(CH3)2SCH3, â€”C(CH3)2S(O)CH3 or â€”C(CH3)2S(O)2CH3 radicals, and Z is either S or NH, and R9 represents a radical formula wherein Y is either O or NH; X represents a bond, O or NH; R20 represents hydrogen, methyl, ethyl, propyl, isopropyl, isobutyl, benzyl, 2-(1-pyrrolidinyl)ethyl, 2-(piperidinyl)ethyl, 2-(1-piperazinyl)ethyl, 2-(4-methylpiperazin-1-yl)ethyl, 2-(1-morpholinyl)ethyl, 2-(1-thiamorpholinyl)ethyl or 2-(N,N-dimethylamino)ethyl radicals.