Patent ID: 8633222
Filing Date: 2014-01-21
Classification: A61K,A61P,C07D

Abstract:
1. A method for the treatment of one or more of pre-senile dementia, early onset Alzheimer's disease, senile dementia, dementia of the Alzheimer's type, Lewy Body dementia, micro-infarct dementia, AIDS-related dementia, HIV-dementia, mild cognitive impairment, age-associated memory impairment, premature amnesic disorder, age-related cognitive disorders, substance-related cognitive disorders, cognitive disorders related to immunodeficiency syndrome, cognitive disorders associated with vascular disorders, schizophrenia, cognitive dysfunction in schizophrenia, attention deficit disorder, attention deficit hyperactivity disorder, attention deficiencies, or learning deficiencies comprising: administering to a patient in need thereof an effective amount of a vinylazacycloalkane compound of Formula (I): wherein: the wavy line represents E geometry about the double bond; X is CR R R wherein the C R R R wherein the C R wherein the aromatic group-containing species can be substituted with one or more of C either R m is 1, 2, 3, or 4; and n is 1, 2, or 3; or an enantiomer, diastereomer, tautomer, or pharmaceutically acceptable salt thereof.