Patent ID: 6900192
Filing Date: 2005-05-31
Classification: A61K,C07C,C07D,C07K

Abstract:
1. A compound of formula (I): wherein: R X is hydroxyl; Z is a substituted alkyl group of the formula -M-Q wherein I′ is —[NR J′ is —[NR K′ is —[NR60′-(CR61′R62′)e′-(CR63′R64′)f′-C(O)]—; R a′, b′, c′, d′, e′ and f′ are independently 0 or 1; i′, j′ and k′ are independently 0 or 1; R R R R R R R R R R R R R R R R D′ is a moiety derived from a GABA analog of the following formula: wherein R R R R R R R R or a pharmaceutically acceptable salt thereof; provided that the compounds are transported across the intestinal wall.