Patent ID: 6232306
Filing Date: 2001-05-15
Classification: A61P,C07D

Abstract:
A compound of the formula: ##STR35##whereinR.sup.1 is hydrogen, C.sub.1-6 -alkyl, C.sub.1-6 -alkyl substituted by fluoro, or C.sub.3-6 -cycloalkyl;R.sup.2 is hydrogen;R.sup.3 is a substituent selected from the group consisting of --CH.sub.2 C(.dbd.CH.sub.2)--COOR, --COOCH.sub.2 C(.dbd.CHR)--COOR, --COOCH.sub.2 OCOR, --COOCH(R)OCOR, --COOCH(R)OCOOR, --COOCH(OCOR)OCOR, --COOCH.sub.2 COCH.sub.2 OCOR, and ##STR36##R is hydrogen or C.sub.1-6 -alkyl;R.sup.4 is hydrogen or hydroxy,R.sup.5 is hydrogen or .omega.-hydroxyalkyl; andX is CH or N, pharmaceutically acceptable salts of said compound, and hydrates of said compound and of said salts.