Patent ID: 8013603
Filing Date: 2011-09-06
Classification: G01N,G01R

Abstract:
1. A method for high throughput screening candidate interactive substances comprising: introducing a measurement sample in a medium into an analytical column; immobilizing the measurement sample on a solid-phase carrier in the analytical column in an NMR-detecting cell; supplying the immobilized measurement sample with a candidate interactive substance through a solution-introducing pipe; applying a magnetic field to the NMR-detecting cell; measuring the interaction between the measurement sample and the candidate interactive substance by solution NMR; supplying a solvent capable of dissociating only the association between the measurement sample and the candidate interactive substance through the solution-introducing pipe to release the candidate interactive substance from the measurement sample; discharging the candidate interactive substance from the NMR-detecting cell through a solution-discharging pipe; and repeating the first supplying step, the measuring step, and the second supplying step.