Patent ID: 8332160
Filing Date: 2012-12-11
Classification: G16B,G16C

Abstract:
1. A method of defining an engineered nucleic acid construct for integration into a genomic locus L of a target organism or a host cell, the method comprising: (A) receiving a plurality of nucleic acid requests {NR (B) expanding each NR (C) arranging the plurality of component polynucleotides into a contiguous arrangement AR (D) repeating the arranging (C) until a set of {AR (E) determining a score S (F) selecting a final contiguous arrangement AR (G) calculating, in response to selection of the AR wherein at least one of the receiving (A), expanding (B), arranging (C), repeating (D), determining (E), selecting (F), and calculating (G) is performed using one or more suitably programmed computers.