Patent ID: 7425618
Filing Date: 2008-09-16
Classification: A61K,A61P,C07K

Abstract:
1. A liquid antibody formulation comprising, in an aqueous carrier: (a) at least 40 mg/ml of antibody that immunospecifically binds to a respiratory syncytial virus (RSV) F antigen, wherein the antibody comprises a variable heavy (VH) complementarity determining region (CDR) 1 having the amino acid sequence of SEQ ID NO:10, a VH CDR2 having the amino acid sequence of SEQ ID NO:19, a VH CDR3 having the amino acid of SEQ ID NO:20, a variable light (VL) CDR1 having the amino acid sequence of SEQ ID NO:39, a VL CDR2 having the amino acid sequence of SEQ ID NO:5, and a VL CDR3 having the amino acid sequence of SEQ ID NO:6; and (b) histidine at a concentration of about 1 mM to about 100 mM.