Patent ID: 9040490
Filing Date: 2015-05-26
Classification: A61P,C07D,C07H

Abstract:
1. A method of preparation of an analogue of cytosine or a physiologically acceptable salt or a prodrug thereof, selected from the group consisting of 1, N 4 , 5 and 6 substituted derivatives of cytosine, 5-azacytosine, or 5,6-dihydrocytosine, wherein said analogue is described by the chemical formulas where wherein the method comprises: a) adding an N b) introducing NaBH c) neutralizing the reducing agent with hydrochloric acid, d) evaporating the mixture, e) pouring the mixture into water, f) extracting the mixture with ethyl acetate or butanol to obtain a mixture of alcohol and an N g) obtaining a pure product by: