Patent ID: 6048872
Filing Date: 2000-04-11
Classification: A61P,C07C,C07D

Abstract:
A compound of the general formula (I): ##STR8## wherein R.sup.1 represents an aryl group optionally substituted by one or more substituents selected from halogen, hydroxy, C.sub.1-6 alkoxy, C.sub.1-6 alkyl, nitro, cyano, hydroxymethyl and trifluoromethyl;R.sup.2 represents hydrogen or C.sub.1-6 alkyl;R.sup.3 represents a group A ##STR9## where the ring is substituted by one to four further substituents selected from C.sub.1-6 alkyl, halogen, trifluoromethyl, and C.sub.1-6 alkoxy;or R.sup.3 represents a group B ##STR10## where the aromatic ring is optionally substituted by up to three further substituents selected from C.sub.1-6 alkyl, halogen, trifluoromethyl, and C.sub.1-6 alkoxy;R.sup.4 represents hydrogen, or C.sub.1-6 alkyl;R.sup.5 represents ZCH.sub.2 CO.sub.2 H wherein Z represents a bond, or O;Y represents (CH.sub.2), where n is 1-3;and physiologically acceptable derivatives thereof.