Patent ID: 6497903
Filing Date: 2002-12-24
Classification: A61K,Y10S

Abstract:
A biodegradable hydrogel comprising a network of polymer chains,wherein said polymer chains are interconnected to one another through spacers, wherein the spacers comprise a crosslinking unit and one or more bonds which are hydrolysable under physiological conditions, wherein the crosslinking unit is derived from a hydroxyalkyl methacrylate unit, and wherein the bonds which are hydrolysable are selected from the group consisting of carbonate bonds, carboxylic acid ester bonds, urethane bonds, anhydride bonds, (hemi)acetal bonds, amide bonds, and mixtures of said bonds, and wherein the polymer chains are based on dextran or derivatised dextran, and wherein said ester bonds are optionally those of lactate, glycolate, or succinate.