Patent ID: 6780860
Filing Date: 2004-08-24
Classification: A61P,C07D

Abstract:
A compound of formula I whereinR1 is hydrogen, halo, cyan , carboxamido, carboalkoxy of two to six carbon atoms, trifluoromethyl, alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, alkanoyloxy of 2 to 6 carbon atoms, amino, mono- or di-alkylamino in which each alkyl group has 1 to 6 carbon atoms, alkanamido of 2 to 6 carbon atoms, or alkanesulfonamido of 1 to 6 carbon atoms; Xâ€”Yâ€”Z is N&boxH;C(R2), N&boxH;C(R2)â€”NH or NHâ€”C(R2)&boxH;CH; R2 is hydrogen, halo, trifluoromethyl, amino, mono- or di-alkylamino in which each alkyl group has 1 to 6 c on atoms, alkoxy of one to six carbon atoms or alkyl of one to six carbon atom and R3 is phenyl, naphthyl, anthracyl, phenanthryl, pyridyl, pyrimidyl, triazinyl, thienyl, furyl, pyrrolyl, pyrazol, indolyl, imidazolyl, benzofuryl, benzothienyl, oxazolyl, or thiazolyl, each optionally substituted with from one to three substituents selected from the group consisting of hydroxy, halo, trifluoromethyl, cyano, amino, mono- or di-alkylamino in which each alkyl group has 1 to 6 carbon atoms, alkoxy of one to six carbon atoms and alkyl of one to six carbon atoms; or a pharmaceutically acceptable salt thereof.