Patent ID: 8652284
Filing Date: 2014-02-18
Classification: A61F,A61L

Abstract:
1. A method of making a kink resistant vascular graft, comprising: positioning a generally tubular ePTFE substrate over a mandrel; applying a base layer of polyurethane dissolved in a solvent to the ePTFE substrate leaving distal and proximal ends of the substrate uncovered, the base layer having a first thickness; longitudinally compressing the ePTFE substrate with applied base layer; applying a sealant layer of polyurethane dissolved in a solvent to the compressed ePTFE substrate with applied base layer, the sealant layer having a second thickness greater than the first thickness; applying a first polyurethane foam layer over the sealant layer to create a preliminary graft assembly; curing the preliminary graft assembly by heating to create a cured graft assembly; helically wrapping a first polyurethane beading with a radiopaque component around the cured graft assembly under tension to embed the first beading into the foam layer; applying a second polyurethane foam layer over the first polyurethane foam layer; covering the second foam layer with a solvent-covered ePTFE tape and helically wrapping the ePTFE tape, under tension, such that the edges of the tape overlap followed by applying a layer of polyurethane to the uncovered proximal and distal ends of the substrate and helically wrapping a second beading over the layer of polyurethane at both the proximal and distal ends.