Patent ID: 6630445
Filing Date: 2003-10-07
Classification: A61K,C07K,C12N

Abstract:
A method of inhibiting a neoplasm in a mammal, said method comprising administering to said mammal a therapeutically effective amount of a compound consisting essentially of recombinant human alpha-fetoprotein (SEQ ID NO:2) or anti-neoplasm fragment thereof selected from the group consisting of Domain I residues 1 to 197 (SEQ ID NO:3). Domain II residues 198 to 389 (SEQ ID NO:4), Domain III residues 390 to 590 (SEQ ID NO:5). Domain I+II residues 1 to 389 (SEQ ID NO:6) Domain II+III residues 198 to 590 (SEQ ID NO:7), and rhAFP Fragment I residues 266 to 590 (SEQ ID NO:8).