Patent ID: 6313116
Filing Date: 2001-11-06
Classification: A61P,C07D

Abstract:
A compound of the formula ##STR7##wherein R.sub.1 is C.sub.3-6 cycloalkyl, or C.sub.1-3 alkyl optionally substituted with one or more fluorine atoms;R.sub.2 is C.sub.1-6 alkyl, C.sub.3-6 cycloalkyl, CF.sub.3, CH.sub.2 CF.sub.3, C.sub.2 F.sub.5 or NR.sub.4 R.sub.5 ;R.sub.3 is a pyrazole, imidazole or isoxazole group of partial formula (A), (B) or (C) ##STR8##NR.sub.4 R.sub.5 is a nitrogen-containing heterocyclic ring;R.sub.6 is C.sub.1-3 alkyl; andR.sub.7 and R.sub.8, which are the same or different, are each H, C.sub.1-3 alkyl, halogen, CF.sub.3 or CN, provided that both are not H;or a pharmaceutically-acceptable salt thereof.