Patent ID: 6124361
Filing Date: 2000-09-26
Classification: C07C,C07D

Abstract:
A compound of the formula ##STR34## wherein n is 0-6; R.sup.1 is hydrogen, (C.sub.1 -C.sub.6)alkyl, or aryl, wherein aryl is selected from phenyl and naphthyl, and wherein said aryl moiety can optionally be substituted with one or more substituents, that are selected, independently, from halo, --SO(C.sub.1 -C.sub.6)alkyl, --SO.sub.2 R.sup.4, --SO.sub.2 NR.sup.5 R.sup.6, (C.sub.1 -C.sup.6)alkyl optionally substituted with from one to seven fluorine atoms, (C.sub.1 -C.sub.6)alkoxy optionally substituted with from one to seven fluorine atoms, amino, nitro, cyano, carboxy, --CO.sub.2 (C.sub.1 -C.sub.6)alkyl, (C.sub.1 -C.sub.6)alkylamino, di-amino phenoxy, anilino and phenylthio; R.sup.4 is --O(C.sub.1 -C.sub.6)alkyl, phenyl or (C.sub.1 -C.sub.6)alkyl; and R.sup.5 and R.sup.6 are selected, independently, from hydrogen, (C.sub.1 -C.sub.6)alkyl and phenyl; with the proviso that R.sup.1 can not be hydrogen when n is zero or 1; or a pharmaceutically acceptable salt thereof.