Patent ID: 6566386
Filing Date: 2003-05-20
Classification: A61K,Y10S

Abstract:
A method of treating a disease characterized by eosinophilia, comprising:measuring an eosinophil count of a patient in determining the need for treatment of a disease characterized by eosinophilia and selected from the group consisting of eosinophilia caused by parasitic disease, infectious disease, malignant tumors, eosinophilic granuloma, Wegener granulomatosis, Kimura disease, sarcoidosis, pemphigus, pemphigoid, dermatitis herpetiformis, eosinophilic leukemia, chronic myeloid leukemia (CML), polycythemia vera (PV), myeloproliferative disorder, pernicious anemia (PA), Hodgkin's disease (HD), idiopathic neutropenia, pulmonary infiltration with eosinophilia syndrome (PIE syndrome), hypereosinophilic syndrome, LÃ¶ffler endocarditis, disseminated eosinophilic collagen disease (DECD), ulcerative colitis, Addison's disease, hyperthyroidism, eosinophilic gastroenteritis, eosinophilic myocarditis, eosinophilic fasciitis, eosinophilic meningoencephalitis, eosinophilic pustular folliculitis, poisoning, eosinophilia accompanied by splenectomy, transfusion, radiation or hemodialysis, and cryptogenic eosinophilia; and administering a pharmaceutically effective amount of a histamine-added human gamma-globulin to said patient, thereby suppressing eosinophilia.