Patent ID: 8618345
Filing Date: 2013-12-31
Classification: A62D,C07F

Abstract:
1. A method of detoxifying a methyl compound, comprising: reacting in vitro within an aqueous solvent, an organic halogenated compound with a methyl compound in the presence of a reducing agent, wherein the reducing agent is capable of reducing at least one selected from the group consisting of arsenic, antimony and selenium, and the reducing agent is at least one selected from the group consisting of reduced glutathione (GSH), oxidized glutathione, cysteine, S-adenosyl cysteine, sulforaphane and mercaptoalcohol, wherein the methyl compound comprises arsenic, and wherein in the reaction between the organic halogenated compound with the methyl compound, the methyl compound is methylated, thereby converting the methyl compound into trimethylarsineoxide, and further converting trimethylarsineoxide into arsenobetaine in the presence of the reducing agent that is at least one selected from the group consisting of reduced glutathione (GSH), oxidized glutathione, cysteine, S-adenosyl cysteine, sulforaphane and mercaptoalcohol.