Patent ID: 7943302
Filing Date: 2011-05-17
Classification: A61P,C12Q,G01N,Y10T

Abstract:
1. A method of identifying a candidate Insulin-Like Growth Factor Receptor (IGFR) pathway modulating agent, said method comprising the steps of: (a) providing an assay system comprising cultured cells that express Chromosome 20 Open reading Frame 23 (C20ORF23) nucleic acid, wherein the C20ORF23 nucleic acid comprises SEQ ID NO: 2; (b) contacting the assay system with a test agent that modulates the expression of C20ORF23; and (c) detecting a change in the assay system in the presence of the test agent of step (b) as compared to the absence of the test agent, wherein the detection of a change in the assay system identifies the test agent as a candidate IGFR pathway modulating agent.