Patent ID: 7084245
Filing Date: 2006-08-01
Classification: A61K,A61P,C07K

Abstract:
1. A compound that binds to and activates the erythropoietin receptor (EPO-R), which compound comprises a peptide dimer having the formula: wherein (i) in each peptide monomer of the peptide dimer, each amino acid is indicated by standard one letter abbreviation, AcG is N-acetylglycine, and 1-nal is 1-naphthylalanine; (ii) each peptide monomer of the peptide dimer contains an intramolecular disulfide bond between the two cysteine (C) residues of each monomer (iii) [“PEG”] comprises at least one linear polyethylene glycol (PEG) moiety, each PEG moiety having a molecular weight of about 20,000 to about 40,000 Daltons.