Patent ID: 7022686
Filing Date: 2006-04-04
Classification: A61K,A61P,C07D

Abstract:
1. A compound of formula I: or a pharmacogically acceptable addition salt thereof, wherein R R  wherein the bicyclic, tricyclic or pentacyclic group is functionalized with one or more substituents selected from the group consisting of: (i) alkyl, alkenyl and alkynyl; wherein each alkyl, alkenyl or alkynyl group is functionalized with one or more substituents selected from the group consisting of aminoalkylcarbamoyl, -aminocycloalkylcarbamoyl, oxo, cyanoalkylcarbamoyl, phosphono, R (ii) aminoalkylcarbamoyl, aminocycloalkylcarbamoyl, oxo, cyanoalkylcarbamoyl, phosphono, R R R n=0, 1, 2 or 3; A is selected from the group consisting of —CH═CH, —(CH each m is independently selected from 1 or 2; X is O or S; Z is selected from the group consisting of a single bond, —O—, —(CH R R wherein said alkyl, alkenyl or alkynyl is either unsubstituted or functionalized with one or more substituents selected from the group consisting of hydroxy, alkoxy, amino, alkylamino, dialkylamino, heterocyclyl, acylamino, alkylsulfonylamino, and heterocyclylcarbonylamino; and