Patent ID: 7407965
Filing Date: 2008-08-05
Classification: A61K,A61P

Abstract:
1. A method of treating hypercholesterolemia, hyperlipoproteinemia, dyslipidemia or atherosclerosis in a mammal comprising administering a conjugate or a pharmaceutically acceptable salt or solvate thereof to the mammal wherein the conjugate is a compound of formula: wherein: DRUG is a compound of formula 518: wherein: nn is 1, 2, or 3: A Y Y R wherein: R R R R R R R R R R W W W W M2 is 0, 1 or 2; M12a is 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12; M12b is 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12; M1a, M1c, and M1d are independently 0 or 1; and M12c is 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12.