Patent ID: 9222881
Filing Date: 2015-12-29
Classification: G01N,G16B

Abstract:
1. A method for measuring a conformational structure of an analyte comprising: processing two-dimensional spectral data of an analyte with a data processor to determine a plurality of conformational components of the analyte in a sample, the analyte comprising at least one protein having a plurality of residues, and wherein the spectral data includes amplitude and phase of a signal emitted by the analyte in response to a plurality of incident light pulses; determining, with the data processor, a first quantitative value of a first conformational component of the analyte, the first quantitative value including a first fraction of a first residue for the first conformational component; and determining, with the data processor, a second quantitative value of a second conformational component of the analyte, the second quantitative value including a second fraction of the first residue for the second conformational component.