Patent ID: 6221837
Filing Date: 2001-04-24
Classification: A61K,A61P,C07K,Y10S

Abstract:
An insulin of the formula I ##STR3##or a physiologically tolerable salt of the insulin of the formula I, whereR.sup.1 is a phenylalanine residue or a hydrogen atom,R.sup.3 is glycine,Y is a genetically encodable amino acid residue,Z isa) the amino acid residue His orb) a peptide having 2 to 35 genetically encodable amino acid residues, having 1 to 5 histidine residues,and the residues A2-A20 correspond to the amino acid sequence of the A chain of insulin or an insulin derivative and the residues B2-B29 correspond to the amino acid sequence of the B chain of insulin or an insulin derivative.