Patent ID: 7862819
Filing Date: 2011-01-04
Classification: A01K,A61K,C12N,C12Y

Abstract:
1. A method for inhibiting the diacylglycerol O-acyltransferase activity of a diacylglycerol acyltransferase-2α (DGAT2α) protein, said method comprising: a) measuring diacylglycerol acyltransferase activity of said DGAT2α protein; and b) contacting said DGAT2α protein with an antibody that inhibits the diacylglycerol O-acyltransferase activity of said DGAT2α protein, wherein the DGAT2α protein comprises an amino acid sequence having at least about 98% identity to the amino acid sequence set forth in SEQ ID NO:2.