Patent ID: 9120854
Filing Date: 2015-09-01
Classification: A61P,C07K,G01N

Abstract:
1. A monoclonal antibody that specifically binds to denatured human CD70 on a sample of formalin fixed, paraffin-embedded cells or tissues that express human CD70, wherein the monoclonal antibody comprises three heavy chain complementarity determining regions (CDRs): heavy chain CDR1, heavy chain CDR2, and heavy chain CDR3, wherein the heavy chain CDRs are identical to the heavy chain CDRs of the antibody SG-21.1C1; and three light chain CDRs: light chain CDR1, light chain CDR2, and light chain CDR3, wherein the light chain CDRs are identical to the light chain CDRs of the antibody SG-21.1C, and wherein the antibody SG-21.1C is produced by the hybridoma deposited with the ATCC and assigned Accession No. PTA-8733.