Patent ID: 7459433
Filing Date: 2008-12-02
Classification: A61K,C07K

Abstract:
1. A method of lowering circulating free fatty acid levels in an individual comprising administering to said individual a composition comprising a carrier and a homotrimeric globular OBG3 (gOBG3) polypeptide fragment in an amount effective to lower circulating free fatty acid levels, wherein said gOBG3 polypeptide fragment is selected from 18-244, 19-244, 20-244, 21-244, 22-244, 23-244, 24-244, 25-244, 26-244, 27-244, 28-244, 29-244, 30-244, 31-244, 32-244, 33-244, 34-244, 35-244, or 36-244, of SEQ ID NO:2 wherein the cysteine at position 36 is substituted with serine.