Patent ID: 8722658
Filing Date: 2014-05-13
Classification: A61P,C07D

Abstract:
1. A compound of Formula (I) selected from the group consisting of: a compound wherein Y is phenyl, Z is 4-cyclohexylphenyl, and s is 0; a compound wherein Y is phenyl, Z is 2-t-butoxycarbonyl-3,4-dihydro-1H-isoquinolin-6-yl, and s is 0; a compound wherein Y is phenyl, Z is 6-bromo-3-chloro-benzothien-2-yl, and s is 0; a compound wherein Y is phenyl, Z is 3-chloro-6-trifluoromethyl-benzothien-2-yl, and s is 0; a compound wherein Y is phenyl, Z is 4-(3-trifluoromethylphenoxy)phenyl, and s is 0; a compound wherein Y is phenyl, Z is 4-(3-trifluoromethylphenylthio)-phenyl, and s is 0; a compound wherein Y is phenyl, Z is 4-(3-chlorophenyl-sulfonyl)-phenyl, and s is 0; a compound wherein Y is phenyl, Z is 4-cyclohexyloxyphenyl, and s is 0; a compound wherein Y is phenyl, Z is (3S)-3-iodo-4-(1-(pyrroldin-1-ylcarbonyl)-pyrrolidin-3-yloxy)phenyl, and s is 0; a compound wherein Y is phenyl, Z is 4-(3-trifluoromethylphenylsulfonyl)-phenyl, and s is 0; a compound wherein Y is phenyl, Z is 3-iodo-4-(phenylmethylamino)-phenyl, and s is 0; a compound wherein Y is phenyl, Z is 3-chloro-6-fluoro-benzo[b]thien-2-yl, and s is 0; a compound wherein Y is phenyl, Z is 4-(3-chloro-5-trifluoromethylpyridin-2-yloxy)-phenyl, and s is 0; and pharmaceutically acceptable salts thereof.