Patent ID: 6476035
Filing Date: 2002-11-05
Classification: A61P,C07D

Abstract:
An indole or 2,3-dihydro-indole derivative having the formula: any of its enantiomers or any mixture thereof, or an acid addition salt thereof, whereinX is â€”Oâ€” or â€”Sâ€”; and Y is â€”CR6R7â€”, â€”CR6R7â€”CR8R9â€”, or â€”CR6&boxH;CR7â€”; or Z is â€”Oâ€” or â€”Sâ€”; W is N; A is selected from a group of formula (II), (III) and (IV) â€ƒwherein the dotted lines mean an optional bond in formulas (II), (III) and (IV) and are absent in formula (I); R1, R2, R3, R12, R13, R14, R15, R16 and R17 are each independently selected from hydrogen halogen, trifluoromethyl, alkyl, alkenyl, alkynyl, cycloalkyl, alkoxy, hydroxy, formyl, acyl, amino, alkylamino, dialkylamino, acylamino, alkoxycarbonylamino, aminocarbonylamino, alkylaminocarbonylamino, dialkylaminocarbonylamino, nitro and cyano; R6, R7, R8 and R9 are each independently selected from hydrogen and alkyl; and R11 is selected from hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, phenyl, naphthyl, phenylalkyl, acyl and formyl.