Patent ID: 8960576
Filing Date: 2015-02-24
Classification: A61C,A61K,C04B

Abstract:
1. A method of making high shear homogenized mineral trioxide aggregate, the method comprising: a. mixing starting mineral trioxide aggregate with a non-aqueous liquid to produce a suspension of the mineral trioxide aggregate and the non-aqueous liquid in a ratio of 1 part mineral trioxide aggregate to between 1 and 100 parts non-aqueous liquid; b. placing the suspension of the mineral trioxide aggregate and the non-aqueous liquid into an instrument that homogenizes by high shear and impact impingement of particles; c. actuating the instrument to reduce the size of the particles; d. repeating step b and step c using the suspension of the mineral trioxide aggregate and the non-aqueous liquid between two and one hundred times to create high shear homogenized mineral trioxide aggregate; and e. evaporating the non-aqueous liquid from the high shear homogenized mineral trioxide aggregate; wherein the method reduces a median maximum particle diameter of the high shear homogenized mineral trioxide aggregate to be at least five times smaller than a median maximum particle diameter of the starting mineral trioxide aggregate.