Patent ID: 8497262
Filing Date: 2013-07-30
Classification: A61P,C07D

Abstract:
1. A method of treating an animal in need of enhancement of memory or cognition comprising administering to the animal an effective amount of a compound of formula (I): or tautomer thereof, or their pharmaceutically acceptable salts, wherein: R is hydrogen, or oxide; Z each R B R each R each R each R each R R Ar is aryl optionally substituted with one or more M or heteroaryl optionally substituted with one or more M; each Q is independently hydrogen, halo, oxo, hydroxy, —C(O)NR each M is independently hydrogen, halo, CF each X is independently NL, oxygen, C(O) each L is independently hydrogen, (C p is an integer selected from 0, 1, 2 and 3; z is an integer selected from 0, 1 and 2; and n is an integer selected from 0, 1, and 2.