Patent ID: 8945363
Filing Date: 2015-02-03
Classification: A61F,A61L,C25D

Abstract:
1. A method of making an implant for use in a surgical procedure, the implant comprising a metal substrate, wherein the metal substrate is of a titanium alloy or zirconium, and wherein the implant comprises an anodised surface layer containing biocidal metal ions absorbed by ion exchange, such that, after implantation, leaching of the biocidal metal ions kills bacteria in the vicinity of the implant and suppresses infection, and the method comprising the successive steps of: (A) forming a surface layer on the substrate which is integral with the metal substrate by growing the layer by an anodising process that is carried out using a solution of phosphoric acid, wherein the surface layer comprises a phosphate; (B) rinsing the surface layer on the substrate; and (C) contacting the surface layer on the substrate with a solution that contains biocidal metal ions, so as to absorb biocidal metal ions by ion exchange into the surface layer, thereby forming a phosphate comprising at least one biocidal metal ion, wherein after contacting with the solution that contains biocidal metal ions, the implant is ready to be implanted.