Patent ID: 7825087
Filing Date: 2010-11-02
Classification: A61K,A61P

Abstract:
1. A composition comprising: (a) about 50 to about 500 g/kg cyclosporine; (b) about 10 to about 70 g/kg hypromellose; (c) about 1 to about 10 g/kg docusate sodium; (d) about 100 to about 500 g/kg sucrose; (e) about 1 to about 40 g/kg sodium lauryl sulfate; (f) about 50 to about 400 g/kg lactose monohydrate; (g) about 50 to about 300 g/kg silicified microcrystalline cellulose; (h) about 20 to about 300 g/kg crospovidone; and (i) about 0.5 to about 5 g/kg magnesium stearate, wherein said cyclosporine is in a form of cyclosporine particles having an effective average particle size of less than 2000 nm in diameter, and wherein at least one surface stabilizer is associated with the surface of said particles.