Patent ID: 6281203
Filing Date: 2001-08-28
Classification: A61K,A61P,A61Q

Abstract:
A composition comprising an oil-in water emulsion containing:(i) at least one compound selected from salicylic acid or a salicylic acid derivative, (ii) at least one compound selected from fatty acid esters of glucose or fatty acid esters of an alkylglucose, and (iii) at least one compound selected from an oxyalkylenated ether of either a fatty acid ester of glucose or a fatty acid ester of an alkylglucose,wherein said oxyalkylenated ether is an oxyethylenated ether, and contains from about 10 to about 100 oxyethylenated groups,wherein said salicylic acid derivative is of a formula (I) or a salt thereof: ##STR3##in which:R.sub.1 represents hydrogen or a saturated, linear, branched or cyclized aliphatic hydrocarbon group or an alkoxy, ester or ketoxy group, or an unsaturated group having at least one conjugated or unconjugated double bonds, wherein these groups contain from 1 to about 22 carbon atoms and optionally are substituted with at least one substituent chosen from halogen atoms, the trifluoromethyl group, the hydroxyl groups in a free form or esterified by an acid having from 1 to about 6 carbon atoms or a carboxyl group, which is free or esterified by a lower alcohol having from 1 to about 6 carbon atoms;R.sub.2 represents a hydroxyl group or an ester of formula (II): ##STR4##where R.sub.4 represents a saturated aliphatic group or an alkenyl group having from 1 to about 18 carbon atoms;R.sub.3 represents hydrogen or a saturated or unsaturated linear or branched chain having from 2 to about 30 carbon atoms, optionally containing one or more substituents as defined above;and wherein the pH of the composition is from 4 to 7.