Patent ID: 6815193
Filing Date: 2004-11-09
Classification: A23G,A23K,A61K,A61Q,C11D,C12N,C12Y

Abstract:
A protease variant comprising amino acid substitutions positions corresponding to the amino acid positions 103, 232, 236 and 245 in the amino acid sequence of the Bacillus amyloliquefaciens subtilisin set forth in SEQ ID NO:3 and further comprising a substitution of one or more amino acids at amino acid positions selected from the group of positions corresponding to positions in the amino acid sequence of the Bacillus amyloliquefaciens subtilisin set forth in SEQ ID NO:3 consisting of 3, 12, 20, 27, 38, 43, 48, 55, 61, 62, 68, 76, 87, 89, 97, 98, 99, 101, 102, 104, 106, 109, 128, 130, 131, 133, 140, 147, 159, 166, 167, 173, 183, 184, 185, 192, 194, 205, 206, 209, 210, 211, 212, 213, 214, 215, 216, 218, 224, 237, 244, 248, 251, 252, 255, 256, 257, 258, 259, 260, 261, 271, 272, and 275.