Patent ID: 8697238
Filing Date: 2014-04-15
Classification: A61F,A61L,B05D,B23K,C22F,Y10T

Abstract:
1. A biomaterial comprising: a substrate made of at least one selected from the group consisting of metal, alloy and ceramic; and a biocompatible material layer laminated on appropriate sections of the substrate, wherein: hydroxyl groups are formed on a surface of the substrate by surface-treating at least one section of the surface, while the biocompatible material layer comprises a polymer containing phosphorylcholine groups, the substrate and the biocompatible material layer are bound via a binder layer, the binder layer being combined, on the one hand, with the hydroxyl groups of the substrate by graft-polymerization and, on the other hand, with the biocompatible material layer by graft-polymerization respectively, the binder layer contains an organic compound having carboxyl groups on the one terminal and methacrylic groups or methylene groups on the other terminal, the carboxyl groups on the one terminal are combined with the hydroxyl groups, and the methacrylic groups or the methylene groups on the other terminal are combined with the polymer containing phosphorylcholine groups by graft-polymerization into the formation of covalent bonds.