Patent ID: 6537983
Filing Date: 2003-03-25
Classification: A61K,A61P,C07J

Abstract:
A pharmaceutical formulation for administration by inhalation comprising a compound of formula (I), whereinR1 represents C1-6 alkyl or C1-6 haloalkyl; R2 represents â€”C(&boxH;O)-aryl or â€”C(&boxH;O)-heteroaryl; R3 represents hydrogen, methyl (which may be in either the &agr; or &bgr; configuration) or methylene; R4 and R5 are the same or different and each represents hydrogen or halogen; and {overscore (-----)} represents a single or a double bond; or a salt or solvate thereof, together with a long-acting &bgr;2-adrenoreceptor agonist which formulation has a therapeutically useful effect in the treatment of inflammatory disorders of the respiratory tract over a period of 24 hours or more.