Patent ID: 8323488
Filing Date: 2012-12-04
Classification: G01N,G03F,H05K

Abstract:
1. A method of performing nano-liquid chromatography comprising: providing a nano-liquid chromatography apparatus on a chip, the apparatus comprising: placing the column inlet in fluid communication with an external source via an inlet port located on a first surface of a packaging jig, in the inlet port being in fluid communication with the column inlet through an internal jig conduit and an outlet port on a second surface of the packaging jig; establishing electronic communication with the detector on the substrate through a printed circuit board in contact with a side of the substrate opposite the packaging jig; injecting a sample including a plurality of sample components into the column using the injector; flowing a mobile phase through the column from the column inlet to the column outlet to separate the plurality of sample components; and detecting, using the detector, a changed property at a column outlet to reveal elution of at least one of the plurality of sample components.