Patent ID: 7259157
Filing Date: 2007-08-21
Classification: A61P,C07D

Abstract:
1. A compound having the Formula (I): or a pharmaceutically acceptable salt thereof, wherein NonAr is a nonaromatic 6 membered ring containing 1 nitrogen ring atom, wherein the remaining ring atoms are carbon; A is a phenyl optionally substituted with 1–5 substituents, each substituent independently is C A is pyrrolyl, imidazolyl, pyrazolyl, triazolyl, thiophenyl, thiazolyl, thiadiazolyl, oxazolyl, or isoxazolyl, each optionally substituted with 1–3 substituents, each substituent independently is —C A is pyridyl, pyradazinyl, pyrimidinyl, or pyrazinyl, each optionally substituted with 1–5 substituents; each substituent independently is —C A is pyrrolophenyl, pyrazolophenyl, triazolophenyl, pyridinoimidazolyl, naphthyridinyl, tetrahydrocyclopentopyrazolyl, quinolinyl, pyrimidinopyrazololyl, benzothiazolyl, benzoimidazolyl, benzoxazolonyl, oxodihydrobenzoxazolyl, indolinonyl, oxadihydroquinolinyl, oxatetrahydroquinolinyl, or purinyl, each optionally substituted with 1–5 substituents, each substituent independently is —C B is aryl(CH B is wherein the phenyl is optionally substituted by 1–3 substituents, each substituent independently is C X is H, OH, F, C