Patent ID: 8951742
Filing Date: 2015-02-10
Classification: A61P,G01N

Abstract:
1. A method for identifying a subject as suitably treated by a cardiac intervention, the method comprising: contacting a portion of a sample from the subject with an antibody having specific binding affinity for growth differentiation factor 15 (GDF-15), thereby forming a complex between the antibody and GDF-15, the antibody having a detectable label; separating the complex formed in said step of contacting from antibody not comprising the complex; quantifying a signal from the detectable label of the antibody comprising the complex formed in said step of contacting, the signal being proportional to an amount of GDF-15 in the sample, whereby an amount of GDF-15 in the sample is calculated; comparing the amount of GDF-15 calculated in said step of quantifying to a reference amount for GDF-15, wherein the reference amount for GDF-15 is 1200 pg/ml; and identifying the subject as suitably treated by a cardiac intervention if the amount of GDF-15 calculated in said step of quantifying is larger than the reference threshold amount for GDF-15.