Patent ID: 6087137
Filing Date: 2000-07-11
Classification: C07C,C12P

Abstract:
A process for conversion of a compound of the Formula (1): ##STR14## into a compound of the Formula (2): ##STR15## comprising contacting a dioxygenase enzyme with a compound of Formula (1) and recovering the resulting compound of Formula (2);wherein:a, b, c and d are each independently selected from CH and CY, or one of a, b, c and d is a nitrogen atom and all of the others are selected from CH and CY;X and Y each independently is selected from the group consisting of alkyl, --OH, --OR, --OCOR, --SH, --SR, --F, --Cl, --Br, --I, --NH.sub.2, --NHR, --NRR.sup.1, --NHCOR, --NRCOR.sup.1, --CN, --COOR, --COOH, --COR, --CONH.sub.2, --CONHR, --CONRR.sup.1, --NO.sub.2, --N.sub.3, --PRR.sup.1, --P(O)RR.sup.1, --P(O)(OH).sub.2, --P(O)(OROH), --P(O)OROR.sup.1, --S(O)R, --SO.sub.2 R, --SO.sub.2 H or --SO.sub.3 H;Z is CH.sub.2, CHR, CRR.sup.1, O, NH, NR, S, C.dbd.O or CHX;R and R.sup.1 are each independently alkyl, aryl or aralkyl; andm has a value of from 0 to 4.