Patent ID: 7618633
Filing Date: 2009-11-17
Classification: A01K,A61K,A61N,A61P,C07K

Abstract:
1. A monoclonal antibody or an antigen-binding portion thereof that specifically binds to and activates CD40, wherein said antibody comprises a heavy chain and a light chain, wherein said heavy chain and said light chain comprise the heavy and light chain CDR1, CDR2 and CDR3 amino acid sequences, respectively, of an antibody selected from the group consisting of: 7.1.2 (ATCC Deposit No. PTA-3601), 10.8.3 (ATCC Deposit No. PTA-3602), 15.1.1 (ATCC Deposit No. PTA-3603), 21.2.1 (ATCC Deposit No. PTA-4549), 22.1.1 (ATCC Deposit No. PTA-4550), 23.5.1 (ATCC Deposit No. PTA-4548), 23.25.1 (ATCC Deposit No. PTA-4551), 23.28.1 (ATCC Deposit No. PTA-4552), 23.29.1 (ATCC Deposit No. PTA-4553) and 24.2.1 (ATCC Deposit No. PTA-4554).