Patent ID: 6998480
Filing Date: 2006-02-14
Classification: C07H

Abstract:
1. A method of obtaining sucralose from a feed mixture comprising 6-O-acyl-4,1′,6′-trichloro-4,1′,6′-trideoxygalactosucrose, other chlorinated sucrose byproducts, and optionally other blocked or partially blocked chlorinated sucrose byproducts comprising the steps of: (a) purifying said feed mixture to obtain an increased purity sucralose precursor stream containing a total amount of said other chlorinated sucrose byproducts and said other blocked or partially blocked chlorinated sucrose byproducts, relative to 6-O-acyl-4,1′,6′-trichloro-4,1′,6′-trideoxygalactosucrose, that is lower than a total amount of said other chlorinated sucrose byproducts and said other blocked or partially blocked chlorinated sucrose byproducts, relative to 6-O-acyl-4,1′,6′-trichloro-4,1′6′-trideoxygalactosucrose, in the feed mixture; said purifying comprising a non-crystallization extraction step; (b) converting said 6-O-acyl-4,1′,6′-trichloro-4,1′,6′-trideoxygalactosucrose in said increased purity sucralose precursor stream to sucralose; (c) crystallizing said sucralose to obtain a crystalline sucralose and a mother liquor; and (d) performing at least three additional sequential crystallizations of said crystalline sucralose to obtain a substantially pure sucralose and additional mother liquor.