Patent ID: 6777412
Filing Date: 2004-08-17
Classification: A01N,C07D

Abstract:
A compound of formula (I) or a stereoisomer thereof: wherein any two of K, L and M are nitrogen and the other is CH;T is oxygen or sulfur; Z is an optionally substituted phenyl group or an optionally substituted heterocyclyl group selected from the group consisting of pyridinyl, pyrimidinyl, pyrazinyl, pyridazinyl, 1,2,3-triazinyl, 1,2,4-triazinyl, 1,3,5-triazinyl, 1,2,4,5-tetrazinyl, 1,2,3-triazolyl, 1,2,4-triazolyl, imidazolyl, thienyl, furyl, pyrrolyl, pyrazolyl, thiazolyl, isothiazolyl, oxazolyl, isoxazolyl, 1,2,4-thiadlazolyl, 1,3,5-thiadiazolyl, oxadiazolyl, piperidinyl, morpholinyl, pyrrolidinyl and tetrahydrofuranyl, and, where appropriate, the corresponding N-oxides; the substituents when Z is the substituted phenyl group or the substituted heterocyclyl group are selected from one or more of the following: halo, hydroxy, oxo, mercapto, C1-4 alkyl, C2-4 alkenyl, C2-4-alkynyl, C1-4 alkoxy, C2-4 alkenyloxy, C2-4 alkynyloxy, halo(C1-4)alkyl, halo(C1-4)alkoxy, C1-4 alkylthio, C2-4alkenylthio, hydroxy(C1-4)alkyl, C1-4 alkoxy(C1-4)alkyl, C3-6 cycloalkyl, C3-6 cycloalkyl(C1-4)alkyl, phenyl, phenoxy, C1-4 alkanoyloxy, cyano, isocyano, thiocyanato, isothiocyanato, nitro, â€”NRâ€²Râ€³, â€”N3, â€”NHCONRâ€²Râ€³, â€”NRâ€²CORâ€³, CONRâ€²Râ€³, CRâ€²&boxH;NORâ€³, CHRâ€²CO2Râ€³, CSNRâ€²Râ€², â€”CO2Râ€², â€”OSO2Râ€², â€”SO2Râ€²â€”SORâ€², SO2ORâ€², SO2NRâ€²Râ€³, â€”CORâ€², â€”OCORâ€², â€”CRâ€²&boxH;NRâ€³, N&boxH;CHNRâ€²Râ€³, NHSO2Râ€² or N&boxH;CRâ€²Râ€³ in which Râ€² and Râ€³ are independently hydrogen, hydroxy, C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, C3-6 cycloalkyl, C3-6 cycloalkyl(C1-4)alkyl, C2-4-alkenyl, C2-4 alkenyloxy, phenyl, phenoxy or benzyl, wherein the phenyl, phenoxy and benzyl groups are optionally substituted with halogen, C1-4 alkyl or C1-4 alkoxy, or when Z is the substituted phenyl group or the substituted heterocyclyl group two adjacent substituents of Z join to form a benzene ring.