Patent ID: 8962608
Filing Date: 2015-02-24
Classification: A61P,C07D

Abstract:
1. A compound of formula I or a pharmaceutically acceptable salt or stereoisomer thereof: R A is selected from aryl, and heteroaryl; n is 0, 1, 2, 3, or 4; p is 2, 3, or 4; R R 1-[(1R,2S,6S and 1S,2R,6R)-2-cyano-6-hydroxycyclohexyl]-3-(phenylamino)-1H-pyrazole-4-carboxamide; 1-[(1S,2R and 1R,2S)-2-cyanocyclohexyl]-3-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1H-pyrazole-4-carboxamide; and 3-[(2-chloropyridin-4-yl)amino]-1-[(1S,2R and 1R,2S)-2-cyanocyclohexyl]-1H-pyrazole-4-carboxamide.