Patent ID: 8053465
Filing Date: 2011-11-08
Classification: A61P,C07D,Y02P

Abstract:
1. A method for treating diabetes, diabetic complications, hyperinsulinemia, hyperglycemia, abnormal lipid metabolism, obesity, AIDS following infection with HIV-1, rejection following organ/tissue transplantation, multiple sclerosis, rheumatoid arthritis, inflammation, allergies, osteoporosis, psoriasis and lichen planus, benign prostatic hypertrophy, lung metastasis of breast and prostatic cancers, hypertension, diuresis, decreased myelosuppression, increased white blood cell count or infectious diseases, comprising administering an effective amount of a bicycloester derivative to a patient in need thereof, wherein the derivative is represented by the following formula (1): wherein R 1 is a substituted or unsubstituted C 1 to C 6 alkyl group, substituted or unsubstituted arylmethyl group, or substituted or unsubstituted arylethyl group; X is CH 2 , CHF or CF 2 ; and n is 1 or 2, or a pharmaceutically acceptable salt thereof.