Patent ID: 6150164
Filing Date: 2000-11-21
Classification: A61K,A61M,B01D,C12M,C12N

Abstract:
A bioartificial filtration device suitable for filtering blood comprising a bundle of semipermeable hollow fibers in a chamber defined by a housing having a perfusion inlet port, a perfusion outlet port and a blood filtrate outlet port, wherein said semipermeable hollow fibers are coated internally and/or externally with a first population of cells selected from the group consisting of nonimmortalized endothelial cells, epithelial cells, or a mixture thereof, and a second population of cells selected from the group consisting of pericytes, vascular smooth muscle cells, mesangial cells or a mixture thereof, wherein opposite ends of said bundle of semipermeable hollow fibers are connected to the perfusion inlet and outlet ports.