Patent ID: 6207413
Filing Date: 2001-03-27
Classification: A61K,A61P,C07K,C12N

Abstract:
An isolated nucleic acid molecule, having a sequence selected from the group consisting of:(a) the nucleotide sequence comprising the coding region of the HUMAN OCR1 as set forth in SID. NO. 3;(b) the nucleotide sequence comprising the coding region of the HUMAN OCR1 as set forth in SID. NO. 5;(c) a nucleotide sequence that hybridizes under stringent conditions to the nucleotide sequence of (a) or (b) and which encodes HUMAN OCR1, wherein said stringent conditions are 30% formamide in 5.times.SSPE (0.18 M NaCl, 0.01 M NaPO.sub.4, pH 7.7, 0.001 M EDTA) buffer at a temperature of 42.degree. C. and remaining bound when subject to washing at 42.degree. C. with 0.2.times.SSPE; or(d) a nucleotide sequence which, as a result of the degeneracy of the genetic code differs from the nucleic acid of (a), (b) or (c) and which encodes HUMAN OCR1.