Patent ID: 8337824
Filing Date: 2012-12-25
Classification: A61K,A61P,C08K

Abstract:
1. A pharmaceutical composition comprising a crosslinked cation exchange polymer salt loaded with a stabilizing amount of a linear sugar alcohol by slurrying in a solution the linear sugar alcohol with the crosslinked cation exchange polymer salt, wherein the stabilizing amount of the linear sugar alcohol is from about 10 wt. % to about 35 wt. % based on the total weight of the composition, and the crosslinked cation exchange polymer salt comprising structural units of Formulae 1 and 2, Formulae 1 and 3, or Formulae 1, 2, and 3, wherein Formula 1, Formula 2, and Formula 3 have the following structures: wherein R A X X either the structural unit of Formula 1 constituting at least about 80 wt. % based on the total weight of the structural units of Formulae 1 and 2, Formulae 1 and 3, or Formulae 1, 2, and 3 in the polymer salt, or the mole fraction of the structural unit of Formula 1 in the polymer salt being at least about 0.87 based on the total number of moles of the structural units of Formulae 1 and 2, Formulae 1 and 3, or Formulae 1, 2, and 3 in the polymer salt.