Patent ID: 8871455
Filing Date: 2014-10-28
Classification: A61K,C07K,G01N

Abstract:
1. A method for assessing radiation injury and exposure in a subject suspected of being exposed to radiation comprising measuring the levels of at least three protein biomarkers in a test sample from the subject, wherein the at least three protein biomarkers are from different biological pathways and selected from the group consisting of salivary amylase, GADD45α, p21 correlating the levels of the at least three protein biomarkers with an assessment of radiation injury and exposure, and determining that the subject has been exposed to radiation or has radiation injury if at least two protein biomarker levels are significantly elevated as compared to control levels or determining that the subject has not been exposed to radiation or has no radiation injury if all tested biomarkers are not elevated as compared to control levels wherein control levels are levels of the at least three protein biomarkers measured in a sample obtained from a subject not exposed to radiation.