Patent ID: 6492141
Filing Date: 2002-12-10
Classification: C12P,Y10S

Abstract:
A process for producing vitamin B12 and precursors thereof having detectable vitamin B12 activity, which is not a continuous process and which comprises the steps of:(a) culturing a strain of the genus Propionibacterium in a first fermenter under anaerobic conditions to obtain a culture of Propionibacterium, (b) transferring at least part of the culture obtained in (a) to a second fermenter and subjecting this culture to oxygen, (c) replacing in the first fermenter at least part of the volume transferred in (b) with fresh culture medium; and (d) repeating steps (a), (b), and (c) at least once, wherein the process is not a continuous process for producing vitamin B12 and the precursors thereof.