Patent ID: 6500837
Filing Date: 2002-12-31
Classification: A61P,C07D

Abstract:
A compound of the Formula I or a pharmaceutically acceptable salt, ester, amide, or prodrug thereof,whereinR1 is hydrogen, lower alkyl, or COOR7, or aryl, heteroaryl, arylalkyl, or heteroarylalkyl optionally substituted with one, two, or three groups independently selected from hydrogen, halogen, lower alkyl, lower alkoxy, hydroxy, cyano, nitro, amino, mono- or dialkylamino, carboxy, alkoxycarbonyl, carbamoyl, sulfamoyl, trifluoromethyl, or alkylthio; R3 is hydrogen or lower alkyl; R2, R4, R5, and R6 independently represent hydrogen, halogen, lower alkyl, lower alkoxy, hydroxy, cyano, nitro, amino, mono- or dialkylamino, carboxy, alkoxycarbonyl, carbamoyl, sulfamoyl, trifluoromethyl, or alkylthio; and R7 is hydrogen or lower alkyl; â€”may or may not be a bond; and R8 is hydrogen or oxo.