Patent ID: 7951334
Filing Date: 2011-05-31
Classification: B82Y,G01Q,G03F,Y10T

Abstract:
1. A method for depositing nucleic acid onto a substrate by direct-write nanolithography comprising the step of: positioning at least one nanoscopic tip relative to a substrate so that the tip and substrate approach each other, and wherein nucleic acid coated on the tip is transferred from the tip to the substrate to generate a stable nucleic acid nanoscale pattern on the substrate which is hybridizable with complementary nucleic acid, wherein the tip is treated to improve adhesion of the nucleic acid to the tip, wherein the nucleic acid which is coated on the tip is part of an ink comprising water, aprotic solvent, nucleic acid, inorganic salt, and surfactant; and wherein the transferring is carried out at a relative humidity sufficiently high so that the transfer occurs.