Patent ID: 6870032
Filing Date: 2005-03-22
Classification: A61K,A61P,C07K,C12N,G01N,Y02A,Y10S

Abstract:
1. A boxed set comprising reagents for the early diagnosis of a flaviviral infection, wherein the reagents comprise: (A) a first antibody, called a capture antibody, which is unlabeled and is either (1) a polyclonal antibody with high affinity for NS1 protein of a (B) a second antibody, called a revelation antibody, which is either (1) a polyclonal antibody directed against NS1 protein in hexameric form or (2) a mixture of monoclonal antibodies directed against NS1 protein in hexameric form, wherein the revelation antibody is conjugated to a label; (C) at least one positive control comprising an NS1 protein of a flavivirus, wherein the NS1 protein is in hexameric form; and, (D) at least one negative control comprising an uninfected human serum.