Patent ID: 7678771
Filing Date: 2010-03-16
Classification: A61K,A61P,C07C,Y10S,Y10T

Abstract:
1. A composition comprising from 25 to 75 mg of L-lysine-d-amphetamine or a salt thereof and having an amphetamine base amount of from 7.37 to 22.1 mg of said amphetamine, said L-lysine-d-amphetamine or a salt thereof providing at least five properties selected from the group consisting of a mean AUC 0-12 h (ng h/mL) from 205.4±42.5 to 611.5±104.5, a mean AUC last (ng h/mL) from 396.7±84.8 to 1237.0±194.0, a mean AUC inf (ng h/mL) from 415.0±80.1 to 1259.5±191.3, a mean C max (ng/mL) from 25.0±5.6 to 74.0±12.9, a mean T max (hours) from 3.1±0.876 to 3.9±1.0, and a mean T 1/2 (hours) from 9.68±1.43 to 10.3±1.7 of amphetamine when orally administered to a human subject.