Patent ID: 8217045
Filing Date: 2012-07-10
Classification: A61P,C07D

Abstract:
1. A compound of formula I wherein X is selected from N or CH; R R R or a pharmaceutically acceptable salt thereof, with the proviso that Compound of formula I is not a compound selected from 6-(6-Acetylamino-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid [4-(9-methyl-3,9-diaza-bicyclo[3.3.1]non-3-ylmethyl)-3-trifluoromethyl-phenyl]-amide, 6-(6-Acetylamino-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid [3-(4-methyl-1-piperazinyl)-5-(trifluoromethye)phenyl]-amide, 6-[[6-[(Cyclopropylcarbonyl)amino]-4-pyrimidinyl]oxy]-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-1-naphthalenecarboxamide, 6-(6-Amino-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid [4-(4-ethyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenyl]-amide, and 7-(6-Amino-pyrimidin-4-yloxy)-isoquinoline-4-carboxylic acid [4-(4-methyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenyl]-amide.