Patent ID: 6022963
Filing Date: 2000-02-08
Classification: C07B,C07H,C40B,Y02P,Y10S

Abstract:
A method of attaching a molecule with a reactive site to a support comprising the steps of:(a) providing a support with a reactive site;(b) binding a molecule to the reactive site, said first molecule comprising a masked reactive site attached to a photolabile protecting group of the formula Ar--C(R.sub.1)(R.sub.2)--O--C(O)--, wherein:Ar is an optionally substituted fused polycyclic aryl or heteroaromatic group or a vinylogously substituted derivative of the foregoing;R.sub.1 and R.sub.2 are independently H, optionally substituted alkyl, alkenyl or alkynyl, or optionally substituted aryl or heteroaromatic group or a vinylogously substituted derivative of the foregoing;to produce a derivatized support having immobilized thereon the molecule attached to the photolabile protecting group; and(c) removing the photolabile protecting group to provide a derivatized support comprising the molecule with an unmasked reactive site immobilized thereon.