Patent ID: 8785416
Filing Date: 2014-07-22
Classification: A61K,A61P

Abstract:
1. A method for the treatment of a neurodegenerative and/or neurovascular disease, in a mammal, comprising administering to a mammal in need thereof an effective amount of a compound of formula (I), wherein: R R R G is selected from —COOR one of A or B is selected from hydrogen, —SO A or B is —SO 3 H or —SO 3 Y; R 4 is selected from hydrogen, C 1 -C 2 alkyl and arylalkyl of less than sixteen carbon atoms, Y is an organic or inorganic cation; or a pharmaceutically acceptable salt thereof; wherein the neurodegenerative and/or neurovascular disease is selected from the group consisting of Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, multiple sclerosis, stroke, transient ischemic brain attack, Huntington's disease, Friedreich's ataxia, spongiform encephalopathies, dementia with Lewy bodies, Pick's disease, mild cognitive impairment, epilepsy, migraine, schizophrenia, bipolar disorder, vascular dementia and cerebrovascular arteriosclerosis.