Patent ID: 7919515
Filing Date: 2011-04-05
Classification: A61P,C07D

Abstract:
1. A method of treatment of diseases and conditions mediated by peroxysome proliferator-activated receptor gamma (PPARγ) wherein said disease or condition is selected from the group consisting of hypertension, obesity, hyperglycemia and atherosclerosis; insulin resistance; type 2 diabetes; peripheral neuropathy, renal insufficiency, and retinopathy, in a mammal subject in need thereof, said method comprising administration to said mammal a compound of formula (I): wherein: W represents COOH group or —COO—C Y represents NH, N—C Z represents O; X represents O, S, NH, N—C R C A represents C n represents an integer from 0 to 4, inclusive; enantiomers thereof and pharmaceutically acceptable salts thereof in a therapeutically effective amount.