Patent ID: 8329149
Filing Date: 2012-12-11
Classification: A61K,A61Q

Abstract:
1. A topical skin lightening composition, comprising a substituted-4-oxobutanoic acid, ester, or amide skin depigmenting agent of Formula I: wherein, where Z is a sulfur atom or a group NR G is an aryl of 6 to 10 carbons optionally substituted with R R R R X is oxygen or nitrogen; Y is H, alkyl of 1 to 6 carbons; alkoxyalkyl of 2 to 12 carbons; or G substituted with R Q is alkyl of 1 to 10 carbons, cycloalkyl of 3 to 6 carbons, alkylaryl the alkyl of which has 1 to 6 carbons and said aryl has 6 to 10 carbons, or optionally substituted with R n is 0, 1, or 2, with the proviso that when Z is NR a cosmetically, dermatologically or pharmaceutically acceptable vehicle.