Patent ID: 7635751
Filing Date: 2009-12-22
Classification: A61K,A61P,C07K

Abstract:
1. A peptide represented by the formula: wherein P1 represents a hydrogen atom, or an amino acid residue or a peptide chain, consisting of 1 to 25 amino acids which may be the same or different and whose side chain may be substituted, P2 represents a neutral amino acid residue whose side chain may be substituted or a basic amino acid residue whose side chain may be substituted, P3 represents a neutral amino acid residue whose side chain may be substituted, an aromatic amino acid residue whose side chain may be substituted or a basic amino acid residue whose side chain may be substituted, P4 represents a bond or a neutral or aromatic amino acid residue whose side chain may be substituted, P5 represents [1] an amino acid residue whose side chain may be substituted, or its amino acid derivative wherein the C-terminal carboxyl group has been reduced to a hydroxymethyl group or formyl group, [2] a hydroxyl group, or [3] a dipeptide chain formed by binding an amino acid residue whose side chain may be substituted, to an amino acid residue whose side chain may be substituted, or its peptide derivative wherein the C-terminal carboxyl group of the dipeptide has been reduced to a hydroxymethyl group or formyl group, and a side chain of each amino acid residue in the formula -Arg-Pro-Arg-Leu-Phe- (SEQ ID NO: 74) or -Gly-Pro- may be substituted; an ester thereof or an amide thereof, or a salt thereof.