Patent ID: 6183971
Filing Date: 2001-02-06
Classification: A61K,C07K,Y10S

Abstract:
A monoclonal antibody which (a) specifically binds to a human betacellulin protein comprising the amino acid sequence of SEQ ID NO:1, (b) specifically recognizes amino acid 31 (Arg) to amino acid 80 (Tyr) of SEQ ID NO:1, (c) neutralizes the cell growth stimulating activity of the human betacellulin protein, (d) does not cross-react with at least human epidermal growth factor, human transforming growth factor a, or mouse betacellulin protein, (e) belongs to the immunoglobulin class of IgG, and (f) is produced by cell lines, Mouse 1A1 (FERM BP 5393), Mouse 2B2 (FERM BP 5394) or Mouse 5E5 (FERM BP 5395).