Patent ID: 6764696
Filing Date: 2004-07-20
Classification: A61K,Y10S

Abstract:
A dosage form for delivery of a therapeutically effective amount of a drug to a target area in the gastrointestinal tract of a mammal, said dosage form comprising:(a) a therapeutically effective amount of a drug; (b) at least one effervescent penetration enhancer present in an amount sufficient to increase the penetration of said drug across said target area of said gastrointestinal tract to permit delivery of a therapeutically effective amount of said drug; (c) at least one non-effervescent penetration enhancer; and (d) an enteric coating maintained over said drug, said at least one effervescent penetration enhancer and said at least one non-effervescent penetration enhancer; wherein said enteric coating prevents the release of said drug, said at least one effervescent penetration enhancer and said at least one non-effervescent penetration enhancer until a time at which said dosage form reaches said target area in said gastrointestinal tract.