Patent ID: 8883182
Filing Date: 2014-11-11
Classification: A61K,A61L,A61P,C12N

Abstract:
1. A method of joining a first tissue surface with a second tissue surface, the method comprising: priming the first and second tissue surfaces by reacting the surfaces with a solution containing hydrogen peroxide under ultraviolet irradiation to create a primed first and second tissue surfaces; removing the unreacted hydrogen peroxide from the first and second primed tissue surfaces; adding to the primed first and second tissue surfaces a solution of a polymerizable agent wherein the solution containing the polymerizable agent does not contain a photoinitiator other than the primed first and second tissue surfaces; and exposing the primed first and second tissue surfaces and the polymerizable agent in the absence of photoinitiators to a source of ultraviolet radiation to create a hydrogel directly covalently bound to and bridging the first and second tissue surfaces.