Patent ID: 6045776
Filing Date: 2000-04-04
Classification: A61K,C07D,Y10S

Abstract:
A process for the production of a metal-complex carboxylic acid amide, which comprises pretreating a metal-complex carboxylic acid mixture, comprising a metal-complex carboxylic acid having at least one noncomplexed carboxyl group and at least one solubilizing substance in dimethyl sulfoxide, with a dehydrating reagent, optionally with the addition of a coupling adjuvant, and then reacting the resulting mixture with an amine of formula IA(NH.sub.2).sub.n (I),in whichA stands for the radical of a natural or synthetic amine, andn stands for numbers 1 to 100to form amide(s) between the said non-complexed carboxyl group and the amine group(s).