Patent ID: 7323555
Filing Date: 2008-01-29
Classification: C07H,Y10S

Abstract:
1. A nucleotide derivative having a fluorescent dye intercalator bound via a linker to a pyrimidine base or a purine base, which, when existing as a member of a single-stranded sequence is selected from the group consisting of: (1) a thymine/uracil derivative represented by Formula (1): wherein the fluorescent dye emits light most intensely when the confronting base is adenine; (2) a cytosine derivative represented by Formula (2): wherein the fluorescent dye emits light most intensely when the confronting base is guanine; (3) an adenine derivative represented by Formula (3): wherein the fluorescent dye emits light most intensely when the confronting base is cytosine; and, (4) a guanine derivative represented by Formula (4): wherein the fluorescent dye emits light most intensely when the confronting base is cytosine or thymine/uracil; wherein R