Patent ID: 7815898
Filing Date: 2010-10-19
Classification: A61K,A61P

Abstract:
1. A method of treating hyperphosphatemia in a subject in need thereof comprising: (a) orally administering during a fasting period, a chewing gum comprising an effective amount of a phosphorous binding agent selected from polyallylamine hydrochloride, polyallylamine carbonate, lanthanum carbonate, magnesium acetate, magnesium carbonate, calcium carbonate, calcium acetate, calcium citrate, calcium alginate, styrene-divinylbenzene anion exchange resins and chitosan, and at least one pharmaceutically acceptable vehicle and/or excipient, and (b) retaining the chewing gum in the mouth for a period of time sufficient for the phosphorous binding agent to sequester phosphorous compounds from the saliva of the subject and reduce salivary phosphorous levels thereby reducing recirculation of the phosphorous compounds in the body of the subject and reducing serum phosphorous levels, wherein the chewing gum is not swallowed.