Patent ID: 6117447
Filing Date: 2000-09-12
Classification: A61K,A61P,Y10S

Abstract:
A percutaneous absorption preparation comprising a support and a plaster layer laminated thereon, said plaster layer comprising tulobuterol in a proportion of not less than 5 wt % in a dissolution state and an adhesive, wherein the adhesive is an acrylic adhesive or a rubber adhesive, and wherein the acrylic adhesive comprises a polymer comprising an alkyl (meth)acrylate, wherein the alkyl group has 4 to 12 carbon atoms, in a proportion of not less than 50 wt %, and wherein the rubber adhesive comprises at least one polymer selected from the group consisting of polyisobutylene and a styrene-diene-styrene block copolymer, and when the adhesive is said rubber adhesive, the plaster layer further comprises at least one additive selected from the group consisting of an ester of a fatty acid having 12 to 16 carbon atoms, monoglyceride of a fatty acid having 8 to 10 carbon atoms, an ester of a dibasic acid having 6 to 10 carbon atoms, a polyoxyethylene alkyl ether having an addition molar number of oxyethylene of 2-5, and a polyoxyethylene alkylphenyl ether having an addition molar number of oxyethylene of 2 to 5, in a proportion of 5 to 50 wt %.