Patent ID: 8883476
Filing Date: 2014-11-11
Classification: C12N,C12P,C12Y,Y02P

Abstract:
1. An isolated mutant of propionyl-CoA transferase supplying lactyl-CoA, which has a gene sequence of SEQ ID NO: 3, in which T669C, A1125G and T1158C are mutated, wherein the propionyl-CoA transferase comprises a) a gene sequence of SEQ ID NO: 3, in which T669C, A1125G and T1158C are mutated and one mutation of the nucleic acid is further introduced to cause mutation of Asp65Gly; b) a gene sequence of SEQ ID NO: 3, in which T669C, A1125G and T1158C are mutated and one mutation of the nucleic acid is further introduced to cause mutation of Asp65Asn; c) a gene sequence of SEQ ID NO: 3, in which T669C, A1125G and T1158C are mutated and one mutation of the nucleic acid is further introduced to cause mutation of Thr199Ile; or d) a gene sequence of SEQ ID NO: 3, in which T78C, T669C, A1125G and T1158C are mutated and one mutation of the nucleic acid is further introduced to cause mutation of Val193Ala.