Patent ID: 7091049
Filing Date: 2006-08-15
Classification: C12Q,G01N,Y10S

Abstract:
1. A method of detecting an analyte of interest in a medium with a diffraction based biosensor having at least one additional detection tag mechanism, comprising: exposing a detection tag material to the medium, the detection tag material tagging the analyte of interest with a measurable parameter in addition to optical diffraction characteristics of the analyte of interest; exposing a biosensor to the medium, the biosensor having a substrate member with a receptive material layer applied to at least one side thereof wherein the receptive material is specific for the analyte of interest such that the analyte binds to the receptive material; separating an unbound detection tag material from a bound detection tag material tagging the analyte of interest; exposing the biosensor to a light source and detecting the presence of the analyte by detecting a diffraction pattern of the transmitted light or reflected light; and detecting the emitted measurable parameter of the detection tag material.