Patent ID: 8557532
Filing Date: 2013-10-15
Classification: A61K,A61P,C12Q,G01N

Abstract:
1. A method for determining a prognosis of a patient with Ewing's sarcoma, said method comprising: (a) determining the level of expression of a gene encoding glutathione S-transferase mu 4 (GSTM4) in a sample of Ewing's sarcoma cells acquired from the patient; and (b) determining the patient has a relatively worse prognosis if the level of expression determined is equal to or greater than a reference level at or above which there is a statistically significant negative correlation between the level of expression of the gene in a sample of Ewing's sarcoma acquired from individuals and the individuals' overall survival; or (c) determining the patient has a relatively better prognosis if the level of expression determined is less than a reference level at or above which there is a statistically significant negative correlation between the level of expression of the gene in Ewing's sarcomas acquired from individuals and the individuals' overall survival.