Patent ID: 8696952
Filing Date: 2014-04-15
Classification: A61K,B01F,B01J,B82Y,C08J,Y10T

Abstract:
1. A process for producing core/shell droplets, the process comprising: providing a microfluidic device comprising at least five microfluidic inlets, including a central microfluidic channel inlet, two inner microfluidic channel inlets, and two outer microfluidic channel inlets, wherein the inner microfluidic channel inlets are arranged on both sides of the central microfluidic channel inlet, and wherein the outer microfluidic channel inlets are arranged adjacent to the inner microfluidic channel inlets; an orifice in fluid communication with the at least five microfluidic inlets; and a microfluidic channel in fluid communication with the orifice; injecting a first fluid into the central microfluidic channel inlet, a second fluid into the inner microfluidic channel inlets, and a third fluid into the outer microfluidic channel inlets, wherein neighbouring fluids are immiscible; flowing the first fluid, second fluid, and third fluid through the orifice and into the microfluidic channel, such that the second fluid surrounds the first fluid to form a coaxial stream within the third fluid; and controlling relative flow rates of each of the first fluid, second fluid, and third fluid, such that during passage of the coaxial stream through the microfluidic channel, the coaxial stream breaks up into segments, thereby forming core/shell fluidic droplets with one or more fluidic cores of the first fluid enveloped by a shell of the second fluid.