Patent ID: 6387703
Filing Date: 2002-05-14
Classification: C12N

Abstract:
A method for modulating gene expression comprising the steps of:selecting a polynucleotide binding agent binding site and polynucleotide binding agent; contacting an organism with said binding site and binding agent; and detecting modulation of gene expression, wherein said polynucleotide binding agent is selected from the group consisting of: malachite green, a photoreactive dye, a free radical generating compound, an iron salt, an iron ion, a radioactive iron radionuclide, isofuran blue, an isosulfan blue derivative, reactive sulfonyl chloride of isosulfan blue, hypocrellins and hypericin, tetrabromorhodamine, Rose Bengal photooxidizing dye, a FotoFenton reagent, 2-mercaptopyridine N-oxide, phenanthrolines, a spontaneous nitric oxide donor, DEANO, spermine NONOate, S-nitrosoglutathione, SNAP, SIN-1, M-7904, 2-hydroxyacetophenone oxime and Fenton's reagent.