Patent ID: 6329533
Filing Date: 2001-12-11
Classification: C07D,C12P

Abstract:
A process for preparing a compound of formula (7) ##STR33##wherein R, R.sub.2 and R.sub.3 are as defined below, which comprises the steps of;reacting the compound of formula (1) ##STR34##wherein R is (R)-1-phenylethylamino or (S)-1-phenylethylamino with a halogenating agent or a sulfonylating agent, andcondensing the resulting compound of formula (5) ##STR35##wherein R is as defined above and Y is halogen, (C.sub.1 -C.sub.4)alkylsulfonyloxy or arylsulfonyloxy with a compound of formula (6) ##STR36##wherein R.sub.2 and R.sub.3 may be the same or different, and each is hydrogen, halogen, (C.sub.1 -C.sub.6)alkyl, trifluoromethyl, (C.sub.1 -C.sub.6)alkoxy, aryl, aryloxy or aryl(C.sub.1 -C.sub.6)alkyloxy, the aryl, aryloxy or aryl(C.sub.1 -C.sub.6)alkyloxy being optionally substituted by one or two halogen atoms, or R.sub.2 and R.sub.3 together may form --OCH.sub.2 O--.