Patent ID: 7772265
Filing Date: 2010-08-10
Classification: A61P,C07D

Abstract:
1. A method of inhibiting tyrosine kinase in a host in need thereof, comprising administering thereto a compound of formula I in which R is A, X is H, —OH, —OA, phenoxy, Ar, —O—CO-A, SO two radicals X together are methylenedioxy or ethylenedioxy, R two radicals R Y is CH or N, Ar is phenyl which is unsubstituted or monosubstituted, disubstituted or trisubstituted by A, A is an unbranched or branched alkyl having 1-10 carbon atoms, in which 1-7H atoms may be replaced by F, Hal is F, Cl, Br or I, n is 1, 2, 3 or 4, and m is 1, 2, 3, 4 or 5, or a salt or a mixture of stereoisomers or isolated stereoisomer thereof.