Patent ID: 7977373
Filing Date: 2011-07-12
Classification: A61K,A61P,C07B,C07C,C07D,C07F,C07H

Abstract:
1. A prodrug represented by an ion channel modulating compound attached to a prodrug moiety, wherein the ion channel modulating compound is a compound of formula (IA), or a pharmaceutically acceptable salt, a stereoisomers or a stereoisomeric mixture thereof: wherein, R wherein the prodrug moiety is selected from the group consisting of: wherein: each n is an integer from 1 to 10; R′ and R″ are independently selected from hydrogen and C each R is independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl and substituted alkynyl; R′″ is alkylene; and each X′ is independently selected from O, NH, S or CH wherein at least one valency of the compound of formula (IA) is substituted with a bond to the prodrug moiety.