Patent ID: 9198989
Filing Date: 2015-12-01
Classification: A61K,A61L,A61N

Abstract:
1. A method of producing a mixture with an activity concentration of a radioisotope in the mixture for treating a target tissue in a vertebra, the method comprising: based on (a) a determined distance between the target tissue and a surface of the mixture, and (b) a dose of radiation to be delivered to the target tissue by the radioisotope, determining an activity concentration of the radioisotope to be achieved in the mixture; producing the mixture having the activity concentration by combining a matrix material and the radioisotope; wherein the mixture is configured such that when placed in the vertebra and when a closest surface of the mixture is at the determined distance away from the target tissue, the mixture delivers substantially the dose to the target tissue independently of a total volume of the mixture placed in the vertebra.