Patent ID: 6043236
Filing Date: 2000-03-28
Classification: C07J,Y10S

Abstract:
A compound according to the formula I ##STR7## wherein A is hydrogen, C.sub.2 -C.sub.18 alkanoyl, (C.sub.6 aryl)carbonyl, C.sub.2 -C.sub.19 alkoxycarbonyl, or (C.sub.6 aryloxy)carbonyl, or a protecting group;B is hydrogen, methyl, or ethyl;R is hydrogen, a straight, branched or cyclic C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.18 alkanoyl, (C.sub.6 aryl)carbonyl, C.sub.2 -C.sub.19 alkoxycarbonyl, (C.sub.6 aryloxy)carbonyl, or a protecting group;X.sup.1 is hydrogen, methyl, ethyl or halogen;X.sup.2 is hydrogen, methyl, ethyl or halogen; andY is methylene or a single bond;and pharmaceutically acceptable salts thereof;the compounds(17E)-16.alpha.-Acetoxy-3-methoxy-19-norpregna-1,3,5(10),17(20)-tetraene;(17E)-16.alpha.-Hydroxy-3-methoxy-19-norpregna-1,3,5(10),17(20)-tetraene; and(17E)-16.beta.-Hydroxy-3-methoxy-19-norpregna-1,3,5(10),17(20)-tetraenebeing excluded.