Patent ID: 6177589
Filing Date: 2001-01-23
Classification: C07C,C07D

Abstract:
A method for the preparation of a cyclic ketone of formula ##STR26##having a cyclanic configuration (1 R)-cis and in which R represents a lower alkyl group and R.sup.1 represents a saturated or unsaturated, linear or branched hydrocarbon group having from 1 to 8 carbon atoms, wherein an epoxide of formula ##STR27##having a cyclanic (1 R) configuration, the group in position 2 being in a trans configuration and the epoxy group being in a cis configuration with respect to that in position 1 of the ring, and in which R represents a lower alkyl group and R.sup.1 represents a saturated or unsaturated, linear or branched hydrocarbon group having from 1 to 8 carbon atoms, is treated, in an inert organic solvent, with an acidic agent consisting of an appropriate Lewis acid or an acidic clay.