Patent ID: 7930104
Filing Date: 2011-04-19
Classification: A61P,C12Q,G16B

Abstract:
1. A method for determining a likelihood that a breast cancer patient will have a beneficial response to treatment with chemotherapy, comprising: measuring expression levels of RNA transcripts of at least two genes selected from BIRC5, MKi67, MYBL2, CCNB1, STK6, MMP11, SCUBE2, ERBB2, GRB7, ESR1, PGR, BCL2, CTSL2, GSTM1, CD68, and BAG1 in a biological sample obtained from a breast tumor of the patient; calculating a risk score (RS) based on said expression levels, wherein said expression levels comprise one or more of the following variables: creating a report based on the RS, comprising an estimate of the likelihood that the patient will have a beneficial response to chemotherapy.