Patent ID: 6136822
Filing Date: 2000-10-24
Classification: A61P,C07C,C07D

Abstract:
A method for preparing a quinolinone compound represented by formula (II), wherein an amide compound represented by formula (I) is reacted with a basic agent, followed by intramolecular ring formation: ##STR11## wherein R.sub.1 represents a hydrogen atom, an alkyl group, an alkyl group containing a hydroxyl group, an alkenyl group, or an aryl group;R.sub.2 represents an alkyl group, an alkenyl group, an aryl group, or an aralkyl group;R.sub.3 represents a reactive carboxyl group; andR.sub.4 to R.sub.7 represent, respectively and independently, a hydrogen atom; a hydroxyl group; an alkyl group; an alkoxy group; an alkenyl group; an alkenyloxy group; an aryl group; an aryloxy group; an aralkyloxy group; a R.sub.8 R.sub.9 N group wherein R.sub.8 and R.sub.9 represent, respectively and independently, a hydrogen atom, an alkyl group, an alkenyl group, an aralkyl group, or an acyl group; a nitro group; or a R.sub.10 OOC group wherein R.sub.10 represents a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, or an aralkyl group; ##STR12## wherein R.sub.1, R.sub.2 and R.sub.4 to R.sub.7 represent, respectively, the same groups as described in formula (I).