Patent ID: 8349553
Filing Date: 2013-01-08
Classification: A61P,G01N

Abstract:
1. An assay for identifying a chemical compound having a potential anti-tumor effect comprising comparing the activities of the compound and a jasmonate derivative known to have anti-tumor activity in at least one of the following: dissociating hexokinase from mitochondria, interfering with hexokinase binding to a voltage dependent anion channel, and binding to hexokinase directly; and selecting a compound having an equal or greater anti-tumor activity as compared with at least one anti-tumor activity of said jasmonate derivative selected from the group consisting of: dissociating hexokinase from mitochondria, interfering with hexokinase binding to a voltage dependent anion channel, and binding to hexokinase directly, thereby identifying a chemical compound having a potential anti-tumor effect.