Patent ID: 6479494
Filing Date: 2002-11-12
Classification: A61P,C07D

Abstract:
A method for treating osteoporosis, tumors, atherosclerosis, rheumatoid arthritis, dysmnesia, Morbus Crohn, atopic dermatitis, psoriasis, diabetes mellitus, ulcerative colitis, inflammatory diseases, allergies, asthma, autoimmune diseases, AIDS or transplant rejection reactions which comprises administering to a subject a compound of the formula I: in whichB is A, OA, NH2, NHA, NAAâ€² or an unsaturated heterocycle which has 1 to 4 N, O and/or S atoms and which is optionally unsubstituted or mono-, di- or trisubstituted by Hal, A and/or OA, Q is absent or is alkylene having 1-6 C atoms, R1, R2 in each case independently of one another are â€”OH, â€”OR5, â€”Sâ€”R5, â€”SOâ€”R5, â€”SO2â€”R5, Hal, â€”NO2, â€”NH2, â€”NHR5 or â€”NR5R6, or R1 and R2 together are â€”Oâ€”CH2â€”Oâ€”, R3, R4 in each case independently of one another are H or A, R5, R6 in each case independently of one another are A, cycloalkyl having 3-7 C atoms, methylenecycloalkyl having 4-8 C atoms or alkenyl having 2-8 C atoms, A, Aâ€² in each case independently of one another are alkyl which has 1 to 10 C atoms and which can be substituted by 1 to 5 F and/or Cl atoms and Hal is F, Cl, Br or I, or a physiologically acceptable salt or enantiomer thereof.