Patent ID: 6426210
Filing Date: 2002-07-30
Classification: A61K,B01D,B01J,C07K,C12N,Y10S

Abstract:
A storage-stable composition of spray-dried particles comprising:an active material selected from the group consisting of proteins, peptides, nucleosides, nucleotides, dinucleotides, oligonucleotides, and viable biological cells, and a protein or protein hydrolysate carrier substance that is water-soluble or water-swellable, and that, on its own, is able to exist in a glassy state with a glass transition temperature (Tg) above 20Â° C., wherein (i) the particles have a Tg above 30Â° C., (ii) the carrier is in a glassy state, and (iii) a storage stable composition is characterized as one which, when stored at ambient temperature for a period of 30 days, maintains at least about 90% of its initial activity or chemical identity measured directly after spray drying.