Patent ID: 8716486
Filing Date: 2014-05-06
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A method of treating or suppressing an oxidative stress disorder, comprising administering to a subject in need thereof a therapeutically effective amount of one or more compounds of Formula I: where R is selected from the group consisting of: where the * indicates the point of attachment of R to the remainder of the molecule; n is 0 or 1; R R R Het is optionally substituted pyridine; M and M′ are independently selected from the group consisting of hydrogen, —C(O)—R R or a pharmaceutically acceptable salt, a solvate, or a hydrate thereof; wherein the oxidative stress disorder is selected from the group consisting of Leber's Hereditary Optic Neuropathy (LHON); Friedreich's Ataxia (FA); CoQ10 deficiency; Parkinson's disease; Huntington's Disease; and diabetes.