Patent ID: 7264963
Filing Date: 2007-09-04
Classification: C07K,C12N,C40B

Abstract:
1. A modular replicable vector, comprising a plurality of vector modules, wherein each vector module is (a) flanked by DNA cleavage sites unique within said vector, and (b) essentially devoid of DNA cleavage sites comprised in a nucleotide sequence selected from the group consisting of V-kappa-1 (SEQ ID NO: 42), V-kappa-2 (SEQ ID NO: 44), V-kappa-3 (SEQ ID NO: 46), V-kappa-4 (SEQ ID NO: 48), V-lambda-1 (SEQ ID NO: 50), V-lambda-2 (SEQ ID NO: 52), V-lambda-3 (SEQ ID NO: 54), VH1A (SEQ ID NO: 56), VH1B (SEQ ID NO: 58), VH2 (SEQ ID NO: 60), VH3 (SEQ ID NO: 62), VH4 (SEQ ID NO: 64), VH5 (SEQ ID NO: 66), and VH6 (SEQ ID NO: 68) at the boundaries between each consensus framework region and each complementarity determining region.