Patent ID: 8575159
Filing Date: 2013-11-05
Classification: A61K,A61P,C07D

Abstract:
1. A compound of the Formula I: wherein: R R or one of R the dashed line ----- represents an optional second bond; R R R or two R R R R —CONR 12 R 13 , z) —NR 12 R 13 , wherein Z is CH 2 , O, S(O) n or NR 10 and n is 0, 1 or 2; ee) halogen, ff) C 6 -C 14 aryl-S(O) 2 —NH—, gg) R 11 NHC(O)NH—O—, and hh) optionally substituted 5-membered monocyclic C 1 -C 4 heteroaryl attached to the triazine moiety via a nitrogen atom; R or R or R C C optionally substituted aryl and heteroaryl groups are unsubstituted or are substituted with 1 or 2 moieties selected from the group consisting of: a) C or a pharmaceutically acceptable salt thereof.