Patent ID: 6100269
Filing Date: 2000-08-08
Classification: C07D

Abstract:
A method of treating a central nervous system disorder in a patient in need thereof, the method comprising administering said patient an effective amount of a compound having the formula: ##STR5## where X is nitrogen or carbon bonded to a substituent species characterized as having a sigma m value which is between -0.3 and about 0.75;n is an integer which ranges from 1 to 2;R individually represents hydrogen or alkyl containing one to five carbon atoms;Z represents alkyl containing one to five carbon atoms;A and A' individually represent hydrogen, alkyl containing one to seven carbon atoms, or halo;A"" represents hydrogen, alkyl containing one to seven carbon atoms, halo or an aromatic group-containing species;the dashed line in the structure represents a C--C single bond;the wavy line in the structure represents that the compound can have an endo or exo form;p is an integer ranging from 0 to 7; andY represents hydrogen, alkyl containing one to seven carbon atoms or an aromatic group-containing species.