Patent ID: 6066748
Filing Date: 2000-05-23
Classification: A61K,C07D

Abstract:
A process of extracting TAXOL from yew tree leaves, where said process comprises:a) concentration of extract from said yew tree leaves using methanol as a solvent;b) distribution of said extract from said yew tree leaves into a two phase system, said two phases comprising a water phase and a chloroform phase;c) separation of said two phase system using a strong anion ion exchange resin as a separation means;d) purification of the pregnant solution obtained from said chloroform phase from said previous separation, using ordinary column chromatography as a purification means;e) further purification of said pregnant solution obtained from said purification, using reverse column chromatography as a purification means;f) further purification of said pregnant solution obtained from said purification, using semi-prep high pressure liquid chromatography as a purification means.