Patent ID: 6362210
Filing Date: 2002-03-26
Classification: A61K,A61P,C07C,C07D,Y02A

Abstract:
A compound of the formula I wherein:R1 denotes a hydrogen atom or a C1-3-alkyl group, R2 denotes a hydrogen atom, R4 denotes a hydrogen atom, R4 and R5 together denote another carbon-carbon bond, A denotes a naphthyl group mono-or disubstituted by a fluorine, chlorine, bromine or iodine atom or by a C1-6-alkyl, C3-7-cycloalkyl or trifluoromethyl group, whilst the substituents may be identical or different, or a naphthyl group, and B denotes a phenylgroup, which is substituted by a carboxy group, whilst the above-mentioned phenyl group may additionally be substituted by a fluorine, chlorine or bromine atom, by a C1-3-alkyl, hydroxy, C1-3-alkoxy, C1-3-alkylsulphonyloxy, pyrrolidino, piperidino, morpholino or N-(C1-3-alkyl)-piperazino group, by an n-C2-3-alkoxy, C2-3-alkenyl or C2-3-alkynyl group substituted in the 2 or 3 position by a di-(C1-3-alkyl)-amino group, by an N-methyl-N-(n-C2-3-alkyl)-amino group substituted in the 2 or 3 position by a di-(C1-3-alkyl)-amino group, by a di-(C1-3-alkyl)-amino group, by an imidazolyl or pyrazolyl group optionally substituted by a C1-4-alkyl group, by a C1-4-allylaminocarbonyl, N-(pyridinylmethyl)-aminocarbonyl, pyrrolidinoaminocarbonyl or piperidinoaminocarbonyl group and may additionally be substituted by another fluorine atom, by another C1-3-alkyl or C1-3-alkoxy group, or a physiologically acceptable salt thereof.