Patent ID: 8415339
Filing Date: 2013-04-09
Classification: A61K,A61P

Abstract:
1. A pharmaceutical composition comprising a carbapenem antibiotic and epicillin, or salts, prodrug ester or prodrug amide derivatives thereof, wherein the carbapenem antibiotic is selected from the group consisting of imipenem, meropenem, panipenem, ertapenem, biapenem, doripenem, saftrinem, lenapenem, tebipenem, tomopenem, SM-216601, ER-35786, R-83201, R 95867, DU-6681, BO-2502A, BO-3482, DK-35C, DA-1131, L-646591, L-084, DZ-2640, CS-834, MK-826, J-110441, J-111225, FR-21818, DX-8739 CL 188624, CL-190294, CL-191121, OCA-983, (4R,5S,6S) 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(R)-1-hydroxyethyl]-3-[methoxymethyl]thio-4-methyl-7-oxo; (4R,5S,6S) 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[2-(aminoethyl)oxy]methyl]thio-6-[(R)-I-hydroxyethyl]-4-methyl-7-oxo; and (4R,5S,6S) 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[(N-acetylamino)methyl] thio-6-[(R)-1-hydroxyethyl]-4-methyl-7-oxo.