Patent ID: 8623496
Filing Date: 2014-01-07
Classification: B23K,G01N,Y10T

Abstract:
1. A patch clamp chip for electrophysiology comprising: a homogenous substrate selected from a group consisting of glass and quartz having a first outer surface and an opposing second outer surface; a crater extending into one of the first and second outer surfaces and defining a crater diameter thereon; and a pore extending between the crater and the other one of the first and second outer surfaces of the substrate, the pore defining a pore diameter that is smaller than the crater diameter and is generally constant along substantially the entire length of the pore, and wherein the length of the pore extends over a majority of a distance between the first outer surface and the opposing second outer surface of the substrate; wherein at least one of the crater and the pore have a surface adapted to provide a gigaseal with respect to a cell membrane placed thereover.