Patent ID: 6050980
Filing Date: 2000-04-18
Classification: A61L

Abstract:
A thromboresistant plastic article for use in contact with blood or blood products, the thromboresistant plastic article comprising:an organic polymeric body formed with at least one exposed surface for contacting blood or blood products, the exposed surface of the body having a surface coating applied thereto, the surface coating comprising the reaction product of a base polymer containing epoxy groups and an antithrombotic agent containing hydroxyl groups;wherein the antithrombotic agent is selected from the group consisting of benzothiazolol, salicylaldoxime, ricinoleic acid, glyoxalbis(2-hydroxyanil), N-(2-hydroxyethyl) pyrrolidine, pinacol, and combinations thereof; andwherein the surface coating further comprises a catalyst which promotes a reaction between the epoxy groups of the base polymer and the hydroxyl groups of the antithrombotic agent and a solvent for forming a homogeneous solution of the base polymer, antithrombotic agent and catalyst.