Patent ID: 6017965
Filing Date: 2000-01-25
Classification: A61K,C07B,C07C,C07D

Abstract:
A compound of the formula: ##STR353## wherein: X is independently selected from the group consisting of, --Br, --Cl, --F, --I, --CF.sub.3, alkyl, --OH, --OCF.sub.3, --O-alkyl, and --O-acyl;R.sub.1 is independently selected from the group consisting of --H, lower alkyl, and --O-acyl;R.sub.2 is independently selected from the group consisting of --H, alkyl, and hydroxyalkyl, or both R.sub.2 s together are imino;R.sub.4 is phenoxy which is optionally substituted with --F, --Cl, --Br, --I, --CF.sub.3, alkyl, --OH, --OCF.sub.3 --O-alkyl, or --O-acyl;provided that when X is H, then R.sub.4 is substituted with meta-fluoro, meta-chloro, ortho-methyl, ortho-fluoro, ortho-chloro, meta-methyl, ortho-OH, or meta-OH; andm is independently an integer from 1 to 5; and pharmaceutically acceptable salts and complexes thereof.