Patent ID: 6479506
Filing Date: 2002-11-12
Classification: A61P,C07D

Abstract:
A compound of formula I, or a salt thereof: whereinY represents hydrogen or C1-6 alkyl; Z represents a group selected from furyl or thienyl, which group may be optionally substituted with 1-2 independent C1-6 alkyl, aryl(C1-6)alkyl, halogen, halo(C1-6)alkyl, cyano, cyano(C1-6)alkyl, hydroxy, hydroxymethyl, C1-6 alkoxy, C3-7 cycloalkyl(C1-6)alkoxy, C3-7 cycloalkoxy, amino(C1-6)alkyl, di(C1-6)alkylamino(C1-6)alkyl, or di(C1-6)alkylaminocarbonyl(C1-6)alkyl substituents; R1 represents C3-7 cycloalkyl, or phenyl, any of which groups may be optionally substituted with 1-2 independent C1-6 alkyl, aryl(C1-6)alkyl, halogen, halo(C1-6)alkyl, cyano, cyano(C1-6)alkyl, hydroxy, hydroxymethyl, C1-6 alkoxy, C3-7 cycloalkyl(C1-6)alkoxy, C3-7 cycloalkoxy, amino(C1-6)alkyl, di(C1-6)alkylamino(C1-6)alkyl, or di(C1-6)alkylaminocarbonyl(C1-6)alkyl substituents; and R2 represents 1,2,4-triazolyl(C1-6)alkyl optionally substituted with 1-2 independent C1-6 alkyl, aryl(C1-6)alkyl, halogen, halo(C1-6)alkyl, cyano, cyano(C1-6)alkyl, hydroxy, hydroxymethyl, C1-6 alkoxy, C3-7 cycloalkyl(C1-6)alkoxy, C3-7 cycloalkoxy, amino(C1-6)alkyl, di(C1-6)alkylamino(C1-6)alkyl, or di(C1-6)alkylaminocarbonyl(C1-6)alkyl substituents.