Patent ID: 6770625
Filing Date: 2004-08-03
Classification: A61K,A61P,Y10S

Abstract:
A pharmaceutical composition comprising:a drug-oligomer conjugate comprising a drug covalently coupled to an oligomeric moiety and wherein the drug is a calcitonin polypeptide; a fatty acid component comprising a fatty acid; and a bile salt component comprising a bile salt; wherein the fatty acid component and the bile salt component are present in a weight-to-weight ratio of between 1:5 and 5:1, wherein the fatty acid component is present in an amount sufficient to lower the precipitation point of the bile salt compared to a precipitation point of the bile salt if the fatty acid component were not present in the pharmaceutical composition, and wherein the bile salt component is present in an amount sufficient to lower the solubility point of the fatty acid compared to a solubility point of the fatty acid if the bile salt were not present in the pharmaceutical composition.