Patent ID: 6564153
Filing Date: 2003-05-13
Classification: G01N,G16H

Abstract:
A method for predicting the presence of at least one congenital or acquired imbalance or therapeutic condition associated with thrombosis or hemostasis from at least one time-dependent measurement profile, comprising:(a) adding one or more reagents to a sample to cause coagulation in said sample and performing at least one time-dependent measurement on said sample by taking a plurality of measurements of a property of said sample over time, which property changes when said sample undergoes coagulation. so as to derive a respective at least one time-dependent measurement profile; (b) defining a set of predictor variables which define the at least onetime-dependent measurement profile, said set of predictor variables including at least (i) rate or (ii) acceleration of fibrin polymerization; (c) deriving a model that represents the relationship between the at least one congenital or acquired imbalance or therapeutic condition associated with thrombosis or hemostasis, and the set of predictor variables; and (d) utilizing the model of step (c) to predict the presence of the at least one congenital or acquired imbalance or therapeutic condition associated with thrombosis or hemostasis in the sample.