Patent ID: 6096321
Filing Date: 2000-08-01
Classification: A61K,C07K,C12N

Abstract:
A ClpG sub-unit of a CS31A protein capsule wherein said ClpG sub-unit comprises an amino acid sequence containing a permissive region, wherein said ClpG sub-unit is modified by at least one heterologous peptide in said permissive region wherein said permissive region is selected from the group consisting ofthe region that covers the signal peptide and the N-terminal end of the mature protein defined by the amino acids located at positions -13 and +8 in SEQ ID NO: 2;the region defined by the amino acids located at position 10 and 58 in SEQ ID NO:2;the region defined by the amino acids located at positions 123 and 164 in SEQ ID NO:2; andthe region defined by the amino acids located at positions 183 and 257 in SEQ ID NO:2.