Patent ID: 7304127
Filing Date: 2007-12-04
Classification: A61K,G01N

Abstract:
1. A polypeptide comprising an amino acid sequence selected from the group consisting of QWDFGNTMCQLLTGLYFIGFFS (SEQ ID NO: 12), SQYQFWKNFQTLKIVILG (SEQ ID NO: 13), APYNIVLLLNTFQEFFGLNNCS (SEQ ID NO: 14), YAFVGEKFRNYLLVFFQK (SEQ ID NO: 15), and SEQ ID NOs: 12-15 with up to one conservative or neutral amino acid substitution, wherein the polypeptide binds with HIV gp120 under physiological conditions and comprises less than 100 contiguous amino acid residues that are identical to the amino acid sequence of the human CCR5 chemokine receptor.