Patent ID: 9060730
Filing Date: 2015-06-23
Classification: A61B,A61K

Abstract:
1. A method for estimating a quantification of at least one predictor promoting at least one multifactorial disease for use in assessment of the risk for developing or progression of the at least one multifactorial disease in a subject, the method comprising: applying a non-endogeneous skin irritation agent in a plurality of skin surface concentrations at a plurality of corresponding skin sites of the subject for a predetermined first period of time, the skin irritation agent being adapted to provoke an unspecific inflammatory response of skin; transforming the non-endogeneous skin irritation agent from an inert state into an active state; assessing in an estimation unit the degree of severity of the inflammatory response to the activated skin irritation agent at each skin site according to a predetermined inflammatory response criteria; on basis of the assessment of the degree of severity of inflammatory response at each skin site, assessing in an estimation unit the at least one predictor; and on basis of the assessment of the at least one predictor and relative impact of the at least one predictor on the progress of the at least one multifactorial disease, estimating in an estimation unit a quantification of the at least one predictor.