Patent ID: 6046163
Filing Date: 2000-04-04
Classification: A61K

Abstract:
A pharmaceutical composition containing cyclosporin for internal or external use, characterized in comprisingfrom 0.1 to 20% by weight of a cyclosporin (I), and a vehicle comprising:(i) from 1 to 60% by weight of at least one polyether (II) of a general formula IIaR-O--(CH.sub.2 CH.sub.2 O--).sub.n H (IIa)wherein n is an integer from 2 to 20, R is H or C.sub.1 -C.sub.3 alkyl,(ii) and/or a compound of general formula IIb ##STR3## wherein R is C.sub.1 -C.sub.3 alkyl; (iii) and from 1 to 60% by weight of a mixture of one or more glyceryl monoesters of C.sub.8 -C.sub.22 fatty acids (III) and one or more polyglyceryl esters selected from hexaglyceryl to pentadecaglyceryl monoesters of C.sub.8 -C.sub.22 fatty acids (IV) in a ratio of components (III)/(IV) of 1:2 to 1:6.