Patent ID: 6642210
Filing Date: 2003-11-04
Classification: A61P,C07D,C07H

Abstract:
A compound having the formula: wherein R1=CH2OH; R3 is selected from the group consisting of CO2R20, â€”CONR7R8, and aryl, wherein the aryl substituent is optionally substituted with from 1 to 3 substituents independently selected from the group consisting of halo, alkyl, and OR20; R7 is selected from the group consisting of hydrogen, straight or branched C1-15 alkyl and C3-8 cycloalkyl, wherein the alkyl substituent is optionally substituted with from 1 to 3 substituents independently selected from the group consisting of aryl and CO2R20, and wherein the optional aryl substituent is optionally substituted with halo; R8 is selected from the group consisting of hydrogen, straight or branched C115 alkyl and C3-8 cycloalkyl; R20 is selected from the group consisting of hydrogen and C1-15 alkyl; and wherein R2 and R4 are hydrogen.