Patent ID: 6720149
Filing Date: 2004-04-13
Classification: B01J,B01L,C12Q,C40B,G01N

Abstract:
A method for concurrently processing multiple biological chip assays comprising the steps of:(a) providing a biological chip plate comprising a plurality of probe arrays and, surrounding the probe arrays, material resistant to the flow of liquid, thereby forming a plurality of test wells, each test well defining a space for the introduction of a sample; (b) introducing into each test well test samples from a plurality ofdifferent patients, wherein each test sample contains target molecules; (c) manipulating the biological chip plate with a fluid handling device that automatically performs steps to carry out reactions between target molecules in the test samples and probes in a plurality of the test wells, wherein the fluid handling device controls temperature, sample handling, substrate handling and washing of the test wells; and (d) interrogating the probe arrays of the biological chip plate with a biological chip plate reader to detect reactions between target molecules and probes in a plurality of the test wells to generate assay results.