Patent ID: 8003075
Filing Date: 2011-08-23
Classification: C07K,G01N

Abstract:
1. A diagnostic kit for assaying human matrix Gla protein in a serum sample, comprising: one or more monoclonal antibodies directed against an epitope in human matrix Gla protein residues 3-15, 35-49, or 35-53, alone or in combination with a monoclonal antibody directed against an epitope in human matrix Gla protein residues 61-79, or 54-84, or combinations thereof, wherein said one or more antibodies are produced by a hydridoma formed by fusion of cells from a mouse myeloma and spleen cells from a mouse previously immunized with a peptide homologous to human matrix Gla protein residues 3-15, 35-49, 35-53, or 61-79, or 54-84.