Patent ID: 6375903
Filing Date: 2002-04-23
Classification: B01J,B82Y,C07B,C07H,C40B,G02B,G03F

Abstract:
Apparatus for use in synthesis of arrays of DNA probes, comprising:(a) a substrate with an active surface on which the arrays may be formed; (b) a flow cell enclosing the active surface of the substrate and having ports for applying DNA synthesis reagents into the flow cell which can be flowed over the active surface of the substrate; and (c) an image former providing a high precision, two-dimensional light image projected onto the substrate active surface, comprising: (1) a light source providing a light beam; (2) a micromirror device receiving the light beam from the source and formed of an array of electronically addressable micromirrors, each of which can be selectively tilted between one of at least two separate positions, wherein in one of the positions of each micromirror the light from the source incident upon the micromirror is deflected away from an optical axis and in a second of the at least two positions of the micromirror the light is reflected along the optical axis; and (3) projection optics receiving the light reflected from the micromirrors along the optical axis and imaging the pattern of the micromirrors onto the active surface of the substrate, wherein the light is directed from the micromirror onto the active surface by reflective optical elements.