Patent ID: 8569282
Filing Date: 2013-10-29
Classification: A61P,C07D

Abstract:
1. A compound of formula I-A: or a pharmaceutically acceptable salt thereof, wherein: R Y is a direct bond or is CO, SO R wherein R 11 is hydrogen or is C 1-6 alkyl, (C 1 -C 6 alkylene)cycloalkyl, aralkyl, or heteroaralkyl, any of which may be optionally substituted with halo, hydroxy, alkyl, alkenyl, cycloalkyl, C 1-3 alkoxy, —CO 2 H, —CO 2 C 1-3 alkyl, cyano, aryl, heteroaryl, —CF 3 , —O—CF 3 , —O—CH 2 F, or —O—CHF 2 ; R R n is 0 or 1; p is 1; A optionally substituted with 1 or 2 halo, methyl, or ethyl groups, or is geminally substituted to form a cyclopropyl ring.