Patent ID: 6156305
Filing Date: 2000-12-05
Classification: A61K

Abstract:
A method for preventing or suppressing tumor growth in a mammal by administering first tumor cells comprising:(a) providing an implantable chamber and first tumor cells contained in the chamber; and(b) implanting the chamber containing the first tumor cells into the mammal, wherein the chamber comprises wall means including an interior surface defining the chamber for holding the tumor cells and an exterior surface defining an interface with the mammalian tissue, the interior surface sufficient to isolate the tumor cells from the cellular immune response of the host tissue, the exterior surface having a conformation which allows growth of vascular structures by the mammalian tissue close to but not substantially into the interface and having a nominal pore size ranging from about 0.6 to 20 microns; wherein the first tumor cells have at least one antigen corresponding to an antigen of the mammal's tumor cells and elicit an immune response by the mammal; and wherein the tumor growth is prevented or suppressed.