Patent ID: 6207374
Filing Date: 2001-03-27
Classification: A61K,A61P,C07K

Abstract:
A method for screening a subject to determine whether said subject is a TSC2-associated disorder carrier or a patient having a TSC2-associated disorder, which method comprises detecting the presence of and/or evaluating the characteristics of TSC2 DNA, TSC2 RNA and/or TSC2 polypeptide in a biological sample from said patient, wherein a difference in the presence and/or characteristics of said TSC2 DNA, TSC2 RNA and/or TSC2 polypeptide between said biological sample and the presence and/or characteristics of TSC2 DNA, TSC2 RNA and/or TSC2 polypeptide in a biological sample from a subject not carrying or afflicted with a TSC2-associated disorder is indicative of the presence, predisposition or tendency of the patient to develop a disorder.