Patent ID: 6294153
Filing Date: 2001-09-25
Classification: A61K,A61P

Abstract:
An aerosol pharmaceutical formulation for pulmonary or nasal delivery comprising i) a pharmaceutical agent, ii) water, iii) a phenol selected from the group consisting of phenol and methyl phenol is a concentration of from 1 to 10 wt./wt. % of the total formulation, and v) a propellant selected from the group consisting of C1-C2 dialkyl ether, butanes, fluorocarbon propellant, chlorofluorocarbon propellant, hydrogen-containing chlorofluorocarbon propellant, and mixtures thereof, and optionally iv) at least one excipient selected from the group consisting of salts, antioxidants, coloring agents, flavouring agents, protease inhibitors, stabilizers, glycerin, polyglycerin, lysine, polylysine and mixtures thereof.