Patent ID: 9034830
Filing Date: 2015-05-19
Classification: A61K,A61P,A61Q

Abstract:
1. A method for treating an ophthalmic condition of the surface or interior of the eyeball or an ocular gland in a human patient in need thereof comprising topically administering a composition to the outer surface of at least one upper eyelid of the patient, said composition comprising (1) a therapeutically effective amount of at least one therapeutic agent effective for treatment of the ophthalmic condition, (2) from 0.001% to 50 wt % of a muscle fasciculating agent selected from the group consisting of caffeine, theobromine, theophylline and pentoxifyline and (3) a pharmaceutically acceptable carrier, wherein said therapeutic agent is selected from the group consisting of anti-glaucoma agents, vasoconstrictors, vasodilators, anticholinergic agents, cholinergic agents, α-agonists, β-agonists, anti-inflammatories, secretogues, antibiotics, mast cell stabilizers and combinations thereof, wherein said administration results in delivery of the therapeutic agent across the eyelid and to target tissue of the eyeball or ocular gland.