Patent ID: 7294333
Filing Date: 2007-11-13
Classification: A61K,C07K,C12N,C12Q

Abstract:
1. A method of modifying the electrophysiological function of a heart of an individual and treating atrial fibrillation or ventricular tachycardia, the method comprising: (a) providing allogeneic or autogeneic fibroblasts expressing an exogenous voltage-gated or inward-rectifier potassium ion channel polypeptide forming a functional ion channel; and (b) implanting said allogeneic or autogeneic fibroblasts into the heart of the individual, such that each implanted cell of said allogeneic or autogeneic fibroblast forms: thereby modifying the electrophysiological function of the heart and treating atrial fibrillation or ventricular tachycardia.