Patent ID: 7132425
Filing Date: 2006-11-07
Classification: A61P,C07D

Abstract:
1. A compound according to formula I wherein R 1 is a lower alkyl having from 1 to 5 carbon atoms; R R Y is independently selected from the group of CH and N to form a pyridine or pyrazine ring, respectively; R —(CH —(CH a nine- or ten-membered bicyclic heterocyclic ring connected by a ring carbon atom, said bicyclic heterocyclic ring containing one hetero atom selected from the group consisting of oxygen, nitrogen or sulfur; and an unsubstituted or mono-substituted six-membered aryl ring connected by a ring carbon atom, said mono-substituted aryl ring being mono-substituted at a position on a ring carbon atom other than the connecting carbon atom with a substituent selected from the group consisting of cyano, halo, nitro, amino, methyl, methoxy, and hydroxy; R R R R R R R m is 0, 1, 2, or 3; n is 0 or 1; p is 1 or 2; U is S, SO, or SO Z is O, S, or NH; ----denotes an optional bond; * denotes an asymmetric carbon atom; or a pharmaceutically acceptable salt thereof.