Patent ID: 7601872
Filing Date: 2009-10-13
Classification: A61K,C07C,C07D,C12N,Y10S

Abstract:
1. A method for introducing a nucleic acid into a cell, comprising the steps of contacting the nucleic acid with a polycation, thereby forming a complex; and incubating the complex with the cell, wherein the polycation has the formula: where: Q is N; L is [(CH R R D is a bond or Q; Z is an amine, a polyamine or a diaminoalkyl optionally substituted with —OH; X a is the number of positive charges divided by the valence of the anion; m and n are 1; r, s, u, and y are 1; i and j are independently an integer from 0 to about 100; k is an integer from 1 to about 100; p is an integer from 1 to about 100; q is an integer from 1 to about 100, and wherein,