Patent ID: 8946180
Filing Date: 2015-02-03
Classification: A01K,A61K,A61P,C12N,G01N

Abstract:
1. A method for the treatment of wet age-related macular degeneration or diabetic retinopathy comprising administering to a subject who has been diagnosed with wet age-related macular degeneration or diabetic retinopathy a composition comprising a RNA compound comprising a double stranded region of RNA in a therapeutically effective amount to reduce levels of a target mRNA, wherein said composition is administered outside the blood-retina barrier and the composition crosses the blood-retina barrier and reduces levels of the target mRNA inside the blood-retina barrier and treats the wet age-related macular degeneration or diabetic retinopathy of the subject who has been diagnosed with wet age-related macular degeneration or diabetic retinopathy, wherein said double stranded region is 21-23 nucleotides in length.