Patent ID: 9121049
Filing Date: 2015-09-01
Classification: A61P,C12N,C12Q,G01N

Abstract:
1. A method for detecting if a cancer cell is radiation resistant, comprising the steps of: (A) individually adding a nanoparticle consisting essentially of a first element and a second element to a first cancer cell and a second cancer cell, wherein the first element is platinum, the second element is at least one selected from the group consisting of: iron, cobalt, palladium, silver, nickel, and gadolinium, and the diameter of the nanoparticle is 3 nm to 12 nm; (B) calculating the uptake amount of the first cancer cell and the uptake amount of the second cancer cell; and (C) comparing the uptake amount of nanoparticle for the first cancer cell and for the second cancer cell, and showing or sending a first signal when the uptake amount of the first cancer cell is at least two folds of the uptake amount of the second cancer cell, wherein the first signal indicates the first cancer cell is resistant to radiation, and wherein the increased uptake amount of the first cancer cell as compared to the second cancer cell is due to copper transporter protein hCTR-1 expression in the first cancer cell.