Patent ID: 6936436
Filing Date: 2005-08-30
Classification: C07K

Abstract:
1. An isolated nucleic acid encoding a polypeptide having least 80% sequence identity to: (a) the amino acid sequence of the polypeptide (SEQ ID NO:140); (b) the amino acid sequence of the polypeptide (SEQ ID NO:140), lacking its associated signal peptide; (c) the amino acid sequence of the extracellular domain of the polypeptide (SEQ ID NO:140); (d) the amino acid sequence of the polypeptide encoded by the full-length coding sequence of the nucleic acid sequence (SEQ ID NQ:139); or (e) the amino acid sequence of the polypeptide encoded by the full-length coding sequence of the cDNA deposited under ATCC accession number 203216, wherein the encoded polypeptide induces chondrocyte proliferation.