Patent ID: 8420086
Filing Date: 2013-04-16
Classification: A61K,A61P,C07K

Abstract:
1. A method of treating a B cell lymphoma or B cell leukemia comprising administering to an individual with a B cell lymphoma or B cell leukemia, an immunoconjugate consisting of (i) an anti-CD22 antibody or antigen binding fragment thereof; and (ii) at least one therapeutic agent attached by a linker to the anti-CD22 antibody or fragment thereof, wherein the therapeutic agent is selected from the group consisting of an anti-B cell antibody, an antigen-binding fragment of an anti-B cell antibody, an immunomodulator, a drug, an anti-angiogenic agent, a proapoptotic agent, a cytokine inhibitor, a chemokine inhibitor, a tyrosine kinase inhibitor, a sphingosine inhibitor, a hormone, a hormone antagonist, an enzyme inhibitor, and an oligonucleotide.