Patent ID: 7976875
Filing Date: 2011-07-12
Classification: A01N,A61K,A61P

Abstract:
1. A method for the breakdown of a biofilm extracellular polysaccharide matrix, and for detachment or removal of the biofilm from a surface to which it is attached or adhered, which method comprises applying an aqueous solvating system solution to a biofilm on human or animal nasal passage or sinus tissue, or on a prosthetic system attached to such tissue, wherein said solution comprises water, an amount of metal ion sequestering agent and an amount of solvating agent for the extracellular polysaccharide matrix effective to break down such matrix and to detach or remove such biofilm from such surface, said solvating agent comprises a cationic or zwitterionic surfactant, and said solution has a pH greater than 5 and does not contain biocide harmful to such tissue.