Patent ID: 7741124
Filing Date: 2010-06-22
Classification: C12Q,G01N

Abstract:
1. A method to determine the concentration of fibrinogen and/or derivatives of fibrinogen in a solution, the method comprising: (a) measuring the absorbance of the solution; (b) adding vancomycin to the solution; (c) allowing the vancomycin and solution to react for between two seconds and ten minutes to form a mixture; (d) measuring the absorbance of the mixture; (e) determining the difference in absorbance between the solution and the mixture; (f) comparing the difference in absorbance against a calibration of absorbance for known concentrations of fibrinogen or fibrinogen derivatives to determine the concentration of fibrinogen and/or derivatives of fibrinogen in the solution, wherein the method is independent of matrix and/or independent of time of coagulation.