Patent ID: 6219566
Filing Date: 2001-04-17
Classification: A61B

Abstract:
A method of measuring concentration of a luminescent compound in a turbid medium, comprising:illuminating a turbid medium with a beam of light having an effective wavelength .lambda..sub.1 to excite luminescence in a luminescent compound being detected in the turbid medium;measuring a luminescence signal F an effective distance of about D1 from the beam of light;measuring a reflectance signal R at wavelength .lambda..sub.1 an effective distance of about D2 from the beam of light wherein the distances D1 and D2 are selected to reduce effects of scattering and absorption variations between turbid samples; andprocessing the measured R and F signals to produce an effective function f(F, R) and comparing f(F, R) to a calibration curve of f.sub.c (F.sub.c, R.sub.c) versus concentration of the luminescent compound in a turbid medium to determine a concentration of the luminescent compound.