Patent ID: 6358995
Filing Date: 2002-03-19
Classification: A61P,C07C,C07D

Abstract:
A compound or a pharmacologically acceptable salt thereof or a hydrate of the salt represented by the formula: wherein R1, R2, R3, R4, R5, R6 and R8 are the same or different from each other and each represents hydrogen, halogeno, optionally substituted lower alkyl, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted lower alkoxy, optionally substituted aryloxy, optionally substituted heteroaryloxy, optionally substituted cycloalkylalkyl, optionally substituted arylalkyl, optionally substituted heteroarylalkyl, optionally substituted cycloalkyloxy, optionally substituted cycloalkylalkyloxy, optionally substituted arylalkyloxy, optionally substituted heteroarylalkyloxy, optionally substituted alkenyl or optionally substituted alkynyl, or alternatively two of R1, R2, R3, R4, R5, R6 and R8 adjacent to each other together with the carbon atoms to which they are bonded respectively may form a ring which may contain a heteroatom or be substituted; A represents an optionally substituted aromatic hydrocarbon ring or an optionally substituted unsaturated heterocycle; B represents an optionally substituted phenyl group; and D represents optionally protected carboxyl.