Patent ID: 6365160
Filing Date: 2002-04-02
Classification: A61K,A61P,C07K,C12N

Abstract:
A polyprotein construct comprising at least two amino acid sequences fused directly or indirectly together, each of said sequences being the sequence of an early open reading frame (ORF) protein of papillomavirus (PV), or an immunogenic variant thereof, or a non-full length fragment that is a deletion mutant of the early ORF protein corresponding to at least 50% of the full length wild-type amino acid sequence, whereini. said construct does not contain both an E6 and an E7 PV protein sequence; ii. said construct does not contain an L2 PV protein sequence; and iii. when said construct consists of only two early ORF PV protein sequences, said protein sequences are from the same PV type.