Patent ID: 7659274
Filing Date: 2010-02-09
Classification: A61P,C07D

Abstract:
1. A compound represented by Formula (I) or a pharmaceutically acceptable salt thereof, wherein: X X X R Q A is vinyl or acetylenyl K is aryl or hetaryl, either optionally substituted by halogen; m is 1; aa is 0 or 1; and provided that the compound is not 3-cyclobutyl-1-[(4-phenoxyphenyl)ethynyl]imidazo[1,5-a]pyrazin-8-amine, 3-cyclobutyl-1-[(1-methyl-1H-imidazol-5-yl)ethynyl]imidazo[1,5-a]pyrazin-8-amine, N-{3-[(8-amino-3-cyclobutylimidazo[1,5-a]pyrazin-1-yl)ethynyl]phenyl}-4-chlorobenzamide or 3-cyclobutyl-1-(pyridin-4-ylethynyl)imidazo[1,5-a]pyrazin-8-amine.