Patent ID: 9005161
Filing Date: 2015-04-14
Classification: A61F,A61K,A61L,A61M

Abstract:
1. A balloon catheter for delivering a therapeutic agent to a tissue, the balloon catheter being sterilized from exposure of the balloon catheter to ethylene oxide and comprising a coating layer overlying an exterior surface of a balloon, the coating layer comprising a therapeutic agent, an antioxidant and an additive, wherein: the therapeutic agent is chosen from paclitaxel, rapamycin, or combinations thereof; the antioxidant is butylated hydroxyanisole; the additive is chosen from PEG-20 sorbitan monooleate, PEG-20 sorbitan monolaurate, PEG-15 2-hydroxystearate, oleth-10, oleth-20, PEG-b-PLA, dioctyl sodium sulfosuccinate, sodium dodecyl sulfonate, polyvinylpyrrolidone, PEG-35 castor oil, sorbitol, lecithin, butyral trihexyl citrate, aleuritic acid, shellolic acid, or combinations thereof; and none of the therapeutic agent in the coating layer is hydrolyzed or oxidized.