Patent ID: 7435550
Filing Date: 2008-10-14
Classification: C07H,C07K

Abstract:
1. A method for detecting a zalpha11 receptor ligand within a test sample, comprising: obtaining a test sample comprising lymphoid cells, hematopoeitic cells, activated T-cells, or cancerous cells, or conditioned medium from lymphoid cells, hematopoeitic cells, activated T-cells, or cancerous cells; contacting the test sample with a polypeptide selected from the group consisting of: (a) the amino acid sequence consisting of SEQ ID NO:2 from amino acid number 20 (Cys), to amino acid number 237 (His); (b) the amino acid sequence consisting of SEQ ID NO:2 from amino acid number 20 (Cys), to amino acid number 255 (Leu); and (c) the amino acid sequence consisting of SEQ ID NO:2 from amino acid number 20 (Cys), to amino acid number 538 (Ser); and wherein a Trp residue between residues 214 to 218 of SEQ ID NO: 2 is mannosylated; and detecting the binding of the polypeptide to a ligand in the sample.