Patent ID: 6584335
Filing Date: 2003-06-24
Classification: A61B,G01N,G02B

Abstract:
Analysis device for determining an analyte in vivo through skin in the body of a patient comprisinga measuring probe having a hollow needle adapted to be pierced into the skin and including a wall being permeable along a partial section of its length which is adapted for penetration into the skin, said permeable partial section defining a measuring section, an optical fiber by which light coupled from a light source into the optical fiber is passed into the hollow needle and thus into the body when the measuring probe is pierced into the skin, wherein the light transported through the optical fiber is modified in the measuring probe by direct reagent-free interaction with interstitial liquid within the body, said modification being characteristic of the presence of the analyte and a measuring and evaluation unit to measure the modification and to derive, on the basis of the modification, information concerning the presence of the analyte in the body, wherein said optical fiber includes a measuring section that extends in at least a part of the measuring section of the hollow needle, said light is modified by interaction with interstitial liquid surrounding said measuring section of said optical fiber in said measuring section of said hollow needle, said interstitial liquid penetrating through said wall of said hollow needle to said measuring section of said optical fiber and the modification of the light characteristic of the presence of the analyte results from an interaction with the interstitial liquid in the treasuring section.