Patent ID: 7332274
Filing Date: 2008-02-19
Classification: G01N,Y10S

Abstract:
1. A process for examining the quality of a microarray comprising a biological material, comprising: providing a substrate; providing a mixture of a probe and a light-emitting or heat-emitting compound that does not hybridize with the probe and can be removed by washing; spotting a predetermined amount of the mixture onto each of a plurality of distinct spots on the substrate to produce the microarray; measuring the amount of light or heat emitted from each spot of the plurality of distinct spots to generate numerical data for each spot; washing the microarray to remove the light-emitting or heat-emitting compound from each of the plurality of distinct spots; and for each spot of the plurality of distinct spots, calculating an arithmetic spotting mean of the amount of light or heat emitted from a spot after spotting based on the numerical data.