Patent ID: 6689612
Filing Date: 2004-02-10
Classification: G01N,Y10T

Abstract:
A method for producing a corrected predicted value for an indicator of hemolysis in a sample, in the presence of methemoglobin (metHb), said method comprising the steps of:i) developing a first primary calibration algorithm for one of a total hemoglobin (Hb), an oxy-hemoglobin (oxy-Hb), or a total hemoglobin-methemoglobin (Hb-methb), for predicting a first value for one of said total Hb, said oxy-Hb, or said total Hb-metHb, in said sample wherein said total Hb, said oxy-Hb, or said total Hb-metHb serves as an indicator of hemolysis and said example; ii) deriving a second primary calibration algorithm for said met-Hb, for predicting a second value for said met-Hb in said sample; and iii) adding said predicted second value for said met-Hb to one said predicted first value for total Hb, said predicted first value for oxy-Hb, or said predicted first value for total Hb-metHb, to produce said corrected predicted value for an indicator or hemolysis.