Patent ID: 9011964
Filing Date: 2015-04-21
Classification: A61K

Abstract:
1. A process for manufacturing nanosized encapsulated drugs, comprising: placing a wafer comprising nanosized dents in a first chamber; supplying a protective material into the first chamber and applying a first layer of the protective material along a top surface of the wafer including said nanosized dents; supplying a nanosized core drug into the first chamber and applying a layer of the nanosized core drug on top of said first layer of protective material including filling said nanosized dents; supplying a protective material into the first chamber again and applying one or more additional layers of protective material on top of said layer of nanosized core drug, wherein type of said one or more additional layers of protective material is one of same as, and different from, said first layer of protective material, and wherein thickness of said one or more additional layers of protective material is one of same as, and different from, said first layer of protective material; transporting the wafer into a second chamber and removing excess of said first and said additional layers of protective material and excess of said nanosized core drug from the wafer, thereby ensuring that the nanosized core drug remains only in the nanosized dents substantially encapsulated by said first and said additional layers of protective material; transporting the wafer into a third chamber, and using one or more of a thermal expansion difference, a vibration, and a vacuum to pick up said substantially encapsulated nanosized drugs from said nanosized dents; transporting said picked up substantially encapsulated nanosized drugs through a passage into a fourth chamber; and supplying a protective material into said fourth chamber and applying one or more additional layers of said protective material around said substantially encapsulated nanosized drugs, wherein said protective material supplied into said fourth chamber is one of a same type and same thickness for each of said one or more additional layers, and different type and different thickness for said each of said one or more additional layers or any combination thereof, wherein type of said one or more additional layers of protective material applied in said fourth chamber is one of same as, and different from, type of said first layer of protective material and said additional layers of protective material applied in said first chamber, wherein thickness of said one or more additional layers of protective material applied in said fourth chamber is one of same as, and different from, thickness of said first layer of protective material and said additional layers of protective material applied in said first chamber, and wherein said applying of said one or more additional layers of said protective material in said fourth chamber further comprises providing one or more of a rotational motion and a helical motion to said substantially encapsulated nanosized drugs within said fourth chamber.