Patent ID: 6632929
Filing Date: 2003-10-14
Classification: A61P,C07K,G01N

Abstract:
A covalent conjugate of a 4â€²-hydroxyazobenzene-2-carboxylic acid derivative (hereinafter HABA) and an avidin-type molecule, said conjugate being referred herein as â€œHABAylated avidinâ€  and having the formula: whereinA is (CH2)n or â€”CH&boxH;CHâ€”, wherein n is an integer from 0-10; B is (CH2)n wherein n is an integer from 2 to 10; m is zero or 1; and Av is the residue of an avidin-type molecule selected from the group consisting of native egg-white avidin, recombinant avidin, deglycosylated avidins, bacterial streptavidin, recombinant streptavidin, and truncated streptavidin.