Patent ID: 6096781
Filing Date: 2000-08-01
Classification: A61K,A61P

Abstract:
A pharmaceutical formulation comprising a compound of formula I: ##STR6## where: R and R.sup.1 are independently hydrogen, hydroxy, C.sub.1 -C.sub.6 alkoxy, OCH.sub.2 Ar, OCO(C.sub.1 -C.sub.6 alkyl), OCOAr; andAr is phenyl or substituted phenyl; or a solvate thereof; and a compound of formula II: ##STR7## where: R.sup.2 and R.sup.3 are independently hydrogen, C.sub.1 -C.sub.6 alkyl, CO(C.sub.1 -C.sub.6 alkyl), or COAr;R.sup.4 is pyrolidin-1-yl, piperidin-1-yl, or hexamethyleneimin-1-yl;where the nitrogen of the R.sup.4 group is optionally the N-oxide; ora pharmaceutical salt or solvate thereof; and pharmaceutical carriers, excipients, or diluents.