Patent ID: 7872138
Filing Date: 2011-01-18
Classification: C07D

Abstract:
1. A compound of formula (XII) wherein Q is selected from the group consisting of O and S; R wherein the aryl, cycloalkyl, heteroaryl or heterocycloalkyl is optionally substituted with one or more substituents independently selected from the group consisting of halogen, hydroxy, C R wherein the C provided that the halogen is not bound to a carbon atom that is bound directly to the 7-position of the 1,2,3,4-tetrahydroisoquinoline core; alternatively, Q, R wherein the 5 to 8 membered monocyclic heterocycloalkyl is optionally substituted with one or more substituents independently selected from halogen, hydroxy, C R wherein the C provided that the halogen is not bound to a carbon atom that is bound directly to the 5- or 8-position of the 1,2,3,4-tetrahydroisoquinoline core; R wherein the C provided that when Q is O, R