Patent ID: 6916620
Filing Date: 2005-07-12
Classification: B01J,C12Q,C40B

Abstract:
1. A method of identifying biological samples comprising: providing a micro-array including a substrate coated with a composition including a population of biological probe modified micro-spheres immobilized in a coating containing a gelling agent, at least one sub-population of said population of micro-spheres containing an optical barcode generated from at least one colorant associated with the micro-spheres and including a biological probe sequence; enzymatically removing a portion of the gelling agent over the micro-spheres such that a first portion of the micro-spheres is submerged in the gelling agent and a second portion is exposed above the gelling agent and is substantially free of gelling agent; contacting said array with a biological sample labeled with one of a fluorescent or chemiluminescent label target; and detecting the optical barcode of said sub-population of micro-spheres due to the interaction of said biological probe and said labeled biological sample target; and identifying the biological sample from said detected optical bar code.