Patent ID: 6541492
Filing Date: 2003-04-01
Classification: A61K,A61P,C07D,G01N

Abstract:
A compound of the following formula or a pharmaceutically acceptable salt or solvate thereof,where n is 2, 3, or 4,R1 is hexyl, heptyl, or C4-6alkyl-phenyl, R2 is butyl or benzyl optionally substituted with 1 or 2 halogen, R3 is butyl, benzyl optionally substituted with a trifluoromethyl group or with 1 to 3 halogen, â€”C4H8OH, p-pyridyl, o-pyridyl, ethylpropionate, propyl, ethyl acetate, o-thiophenmethyl, 2,3-methylenedioxobenzyl, 2-thiazolemethyl, 2-furfuryl, R4 is â€”COOH, â€”NHC(O)NH2, â€”NHS(CH3)O2, â€”S(NH2)O2, hydantoin, â€”OH, â€”OCH2CO2H, â€”OCH2CONH2, â€”OCH3, R5 is hydrogen or R5 and R4 are bonded together to form a methylenedioxo ring.