Patent ID: 8377643
Filing Date: 2013-02-19
Classification: G01N

Abstract:
1. An analyte detection system comprising: a first flow path including a sample loading region, a conjugate region comprising a mobilizable conjugate complex, and a capture region comprising an immobilized binding partner capable of specifically binding to a target analyte, and a second flow path including a sample entry region, a substrate region comprising a substrate entity, and a substrate entry region, wherein said substrate region is positioned upstream of said substrate entry region, wherein the first flow path and the second flow path are in different planes and connected through the sample entry region, wherein the substrate entry region comprises a semi-permeable membrane that establishes fluid communication between the first and second flow paths, and wherein said semi-permeable membrane has a porosity such that the substrate entity may pass to the first flow path from the second flow path, but mobilizable conjugate complex cannot pass from the first flow path to the second flow path.