Patent ID: 7189739
Filing Date: 2007-03-13
Classification: A61P,C07D

Abstract:
1. A compound of the formula: and the pharmaceutically acceptable salts thereof, wherein each of Z where each R each of said alkyl optionally including one or more heteroatoms selected from O, S, and N, each of said aryl optionally including one heteroatom selected from O, S, and N, each of said alkyl being optionally substituted by one or more substituents selected from the group consisting of halo, OR, SR, NR and each of said aryl being optionally substituted by one or more substituents selected from the group consisting of halo, OR, SR, NR R wherein X Y is optionally substituted alkyl, optionally substituted aryl, or optionally substituted arylalkyl or two Y taken together may form an alkylene (2–3C) bridge; n is 0, 1 or 2; X Ar consists of one or two phenyl moieties directly coupled to X R each of said alkyl optionally including one or more heteroatoms which are selected from O, S and N, each of said alkyl being optionally substituted by one or more substituents selected from the group consisting of halo, OR, SR, NR and each of said aryl being optionally substituted by one or more substituents selected from the group consisting of halo, OR, SR, NR R