Patent ID: 6365342
Filing Date: 2002-04-02
Classification: A61K,C07K

Abstract:
A method for detecting an anti-virus activity of calcium-dependent lectins comprising the steps of.(a) culturing cells in the presence of virus(es) to prepare virus(es)-infected cells, (b) presenting the virus(es)-infected cells in the presence or absence of a calcium-dependent lectin, (c) comparing gross area of virus(es)-infected focus formed in the presence of a calcium-dependent lectin with that formed in the absence of a calcium-dependent lectin, and (d) evaluating from the comparison results in step (c) an inhibition level by the calcium-dependent lectin on budding of virus in said infected cells, wherein the calcium-dependent lectin comprises an N-terminal region containing cysteine, a collagen-like region, a neck region and a carbohydrate recognition domain.