Patent ID: 6190690
Filing Date: 2001-02-20
Classification: A61F,A61K,A61L

Abstract:
A ketoprofen patch comprising:a moisture permeable backing;a moisture non-permeable primer on said backing, said primer being formed of a material selected from the group consisting of an acrylic adhesive and a rubber adhesive;a moisture-permeable drug layer containing ketoprofen in a therapeutically effective amount, said drug layer being on said primer and being separated from said backing by at least said primer, wherein said drug layer is a matrix comprising 10-80 wt % of ketoprofen and a mixture of PVA and an acrylic emulsion and at least one compound selected from the group consisting of ethylenevinyl acetate (EVA) emulsion and a synthetic rubber latex based on a total amount of drug solutions; anda skin adhesion layer having a release controlling function of a drug solution, said skin adhesion layer having a thickness in the range of between substantially 5 to 40 .mu.m and comprising an acrylic adhesive,said drug layer and said adhesion layer being separate layers within a complex laminated structure with said skin adhesion layer on said drug layer.