Patent ID: 7879834
Filing Date: 2011-02-01
Classification: A61K,A61P,C07D

Abstract:
1. A compound formula (I) or pharmaceutically acceptable salts thereof, wherein Each of R Z Z L is a bond, an aliphatic group, C —S(O) G is a monocycloheteroaliphatic group containing at least one N atom, adamantyl, or a bicyclic or a tricyclic group of the formula (III) wherein the monocycloheteroalipahtic group, the adamantyl, and the bicyclic or tricyclic group are connected to L via any ring atom including those in X Bond r is a single or double bond and when ring B is present, bond r is fused with B; Ring B, when present, is a 5-6 membered cycloaliphatic or heterocycloaliphatic ring, and is optionally substituted with 1-3 of oxo, Q X Each Q Each Q Each Q Each Q Each Q Each i is independently 1, 2, or 3; Each m and n is 2; Each p is 0; Each y is independently 0 or 1; Each z is independently 0, 1, or 2; Each t is 1 to 4; and Provided that when L is —C(O)—CH L is —S(O) L is aliphatic, and R