Patent ID: 7718769
Filing Date: 2010-05-18
Classification: A61K,C07K

Abstract:
1. A method of making a compound of Formula (I) or pharmaceutically acceptable salt or ester thereof, wherein A and B are independently selected from R G is selected from —R W is selected from a substituted or unsubstituted heterocyclic, or a substituted or unsubstituted heteroaromatic; Each R Each of R Each of R m is 0, 1, or 2; n is 0, 1, or 2; and s is 1-6; comprising the step of reacting a compound of Formula (II) wherein W is a leaving group or hydroxy and all other variables are as defined in Formula (I), with a nucleophilic substituted or unsubstituted heterocyclic, or a nucleophilic substituted or unsubstituted heteroaromatic, thereby producing the compound of Formula I.