Patent ID: 6723858
Filing Date: 2004-04-20
Classification: A61K,C07J,Y10S

Abstract:
A compound of the formula: wherein:I. Ra-Rk are defined as follows: A) each Ra, Rb, Rc, Rd, Rg, Rh, R1, Rk independently is â€”R1, â€”OR1, â€”OCOR1, â€”SR1, â€”F, â€”NHR2, â€”Br, or â€”I; and Re is â€”R1, â€”OR1, â€”OCOR1, â€”SR1, â€”F, â€”NHR2, â€”Br, â€”I or â€”Câ‰¡CH; or B) each Ra, Rb, Rc, Rd, Rk, independently is â€”R1, â€”OR1, OCOR1, â€”SR1, â€”F, â€”NHR2, â€”Br, or â€”I; and each Rg, Rh, Ri, independently is &boxH;O, â€”R1, â€”OR1, â€”OCOR1, â€”SR1, â€”F, â€”Br, or â€”I; and Re is &boxH;O, â€”R1, â€”OR1, â€”OCOR1, â€”SR1, â€”F, â€”Br, â€”I or â€”Câ‰¡CH; and II. Zâ€² is defined as follows: A) Zâ€² is X, where X is >COR1, B) Zâ€²is where Rn is â€”R1, â€”OR1, â€”Sr1, â€”F, â€”NHR2, â€”Br, or â€”I; and Xâ€² is X, as defined above; or Xâ€² is >C&boxH;O; and III. Zâ€³ is defined as follows: A) Zâ€³ is â€”Oâ€”; or B) Zâ€³ is â€ƒwhere Rp is â€”R1, â€”Or2, â€”SR1, â€”F, â€”NHR2, â€”Br or â€”I; where, in each formula set forth above, each R1 and R2 independently is â€”H, or an alkyl, alkenyl or alkynyl group of up to 6 carbons.