Patent ID: 6472563
Filing Date: 2002-10-29
Classification: A61K,A61P,C07B,C07C

Abstract:
A process for the preparation of highly pure (R,R)-formoterol L-tartrate comprising crystallizing a first polymorph (C) of (R,R)-formoterol L-tartrate from aqueous isopropyl alcohol, said first polymorph having peaks at the diffraction degrees with the intensity shown below in an X-ray powder diffraction pattern:Peaknumber2-ThetaIntensity16.4100.029.014.4311.114.8412.413.9512.919.7613.519.5714.015.1815.019.7915.416.91015.718.11116.312.81217.564.91319.447.31419.944.81521.329.31622.331.51722.935.81824.180.01924.717.62025.511.32126.015.62226.89.12327.48.52428.410.82529.08.52630.58.12732.710.92834.27.92935.79.33036.46.63137.37.93237.89.13339.310.03439.611.43541.15.73642.34.7.