Patent ID: 7879314
Filing Date: 2011-02-01
Classification: A61B,A61K,Y02A

Abstract:
1. A method for the diagnosis of an inflammatory disease of a joint comprising (i) administering to a subject a diagnostically effective amount of wherein C stands for a radical (II) or (III) wherein the position that is labelled with the star means the point of linkage with radical A and wherein A stands for a group (IV), (V), (VI), (VII), or (VIII) wherein R R R E R b means the number 2 or 3; and (ii) exposing the joint to be imaged to light of a wavelength between 700 nm and 900 nm and (iii) measuring fluorescence at multiple time points within 500 seconds after administration of said dye, wherein the distribution of said indocarbocyanine dye in the joint regions suspected of having inflammation is indicative of the presence of inflammatory joint disease.