Patent ID: 6818786
Filing Date: 2004-11-16
Classification: C07C

Abstract:
A new process for the preparation of ethyl 3-ethoxy-4-ethoxycarbonyl-phenylacetate of formula 1 which comprises a. reacting 4-methylsalicylic acid with diethyl sulfate in presence of potassium carbonate in a polar organic solvent, filtering a resultant reaction mixture, removing the organic solvent by evaporation and distilling a residue to obtain ethyl-2-ethoxy-4-methylbenzoate of formula 3 b. a brominating ethyl-2-ethoxy-4-methylbenzoate of formula 3 with brominating agent in an organic solvent to yield ethyl-4-bromomethyl-2-ethoxy benzoate of formula 4 c. reacting ethyl-4-bromomethyl-2-ethoxy benzoate with CO in ethyl alcohol, removing the solvent by evaporation to obtain ethyl 3-ethoxy-4-ethoxycarbonyl-phenylacetate of formula 1.