Patent ID: 7749371
Filing Date: 2010-07-06
Classification: A61B,G01N

Abstract:
1. A method for determining an analyte concentration in a physiological sample, the method comprising: (a) introducing the physiological sample into an electrochemical cell, the electrochemical cell comprising: (b) applying a first electric potential having a first polarity to the electrochemical cell and measuring cell current as a function of time to obtain a first time-current transient; (c) applying a second electric potential having a second polarity to the cell, wherein the second polarity is opposite the first polarity, and measuring cell current as a function of time to obtain a second time-current transient; and (d) calculating a first current value from the second time-current transient; (e) calculating a second current value from the second time-current transient and a third current value from the first time-current transient; (f) calculating a ratio which comprises the second current value divided by the third current value; and (g) multiplying the first current value less a background value by said ratio to derive analyte concentration.