Patent ID: 8116840
Filing Date: 2012-02-14
Classification: A61B

Abstract:
1. An in vivo analyte sensor calibration system, comprising: an in vivo analyte sensor, at least a portion of the sensor subcutaneously positioned to generate one or more signals; a calibration sensor configured to be placed in contact with a blood sample from an off-finger calibration site to provide a calibration measurement; and a calibration device in signal communication with one or more of the in vivo analyte sensor or the calibration sensor to calibrate the in vivo analyte sensor by determining whether a quality of the calibration measurement is suitable for calibration, and converting the one or more signals from the in vivo analyte sensor into a corresponding one or more analyte concentration values using the calibration measurement if the quality of the calibration measurement is determined to be suitable; wherein the calibration device is configured to determine a temperature compensated analyte concentration value based at least in part on the one or more analyte concentration values and a temperature compensation factor; wherein the calibration device is further configured to determine a lag compensated analyte concentration value by applying a lag factor to a change in the temperature compensated analyte value over a time period between two acceptable calibration points divided by the time period between the two acceptable calibration points added to the temperature compensated analyte value; and wherein the two acceptable calibration points is deemed acceptable based on at least one evaluation standard being met.