Patent ID: 6897023
Filing Date: 2005-05-24
Classification: C12Q

Abstract:
1. A method for determining the relative abundance of a nucleic acid sequence between first and second nucleic acid populations, comprising: (a) contacting a reference library which comprises multiple copies of a selected nucleic acid sequence with: a first probe, derived from a first nucleic acid population, having a sequence which is complementary to said selected sequence and a terminal first sample ID (SID) sequence, and a second probe, derived from a second nucleic acid population, having a sequence which is complementary to said selected sequence and a terminal second sample ID (SID) sequence; wherein said first and second probes are present in relative amounts proportional to the relative abundance of the selected nucleic acid sequence in the first and second nucleic acid populations, respectively, whereby, upon said contacting, (b) detecting the presence of unhybridized first SID sequences and/or unhybridized second SID sequences, as an indication of the relative amounts of hybridized first probe and hybridized second probe.