Patent ID: 7348337
Filing Date: 2008-03-25
Classification: A61P,C07D

Abstract:
1. A compound of Formula I, including pharmaceutically acceptable salts thereof, wherein: Z is Q is selected from the group consisting of: —W— is R R R n is 0-6; R R represents a carbon-carbon bond or does not exist; D is selected from the group consisting of hydrogen, (C A is selected from the group consisting of phenyl and heteroaryl; wherein said phenyl and heteroaryl are each independently optionally substituted with one to three same or different members selected from the group K; and heteroaryl is selected from the group consisting of pyridinyl, pyrazinyl, pyridazinyl, pyrimidinyl, furanyl, thienyl, benzothienyl, thiazolyl, isothiazolyl, oxazolyl, benzooxazolyl, isoxazolyl, imidazolyl, benzoimidazolyl, 1H-imidazo[4,5-b]pyridin-2-yl, 1H-imidazo[4,5-c]pyridin-2-yl, oxadiazolyl, thiadiazolyl, pyrazolyl, tetrazolyl, tetrazinyl, triazinyl and triazolyl; with the proviso that when m is 1 and A is benzoimidazolyl, 1H-imidazo[4,5-b]pyridin-2-yl or 1H-imidazo[4,5-c]pyridin-2-yl, D is not —H; R B is selected from the group consisting of (C F is selected from the group consisting of (C G is selected from the group consisting of (C K is selected from the group consisting of (C R X is selected from the group consisting of NR R J is selected from the group consisting of (C R