Patent ID: 8747751
Filing Date: 2014-06-10
Classification: B01J,B01L,B82Y,C12N,C12Q,G01N,G02B

Abstract:
1. A scanning sensor system for sequencing a nucleic acid comprising: a substrate comprising a plurality of substantially parallel excitation waveguides, and a plurality of substantially parallel collection waveguides, the excitation waveguides and collection waveguides crossing to form a two-dimensional array of intersection regions where an excitation waveguide and a collection waveguide cross and provide evanescent optical communication with an optical sensing site adjacent each crossing; wherein each optical sensing site is adjacent to and in optical communication with one of the excitation waveguides and one of the collection waveguides at the intersection regions, so that the excitation waveguides couple into the optical sensing site through an evanescent electromagnetic field and the collection waveguides couple into the optical sensing sites through an evanescent electromagnetic field; one or more switchable light sources, comprising a scanning light source input and a photo-cleaving light source input, coupled to and in optical communication with the excitation waveguides of the substrate; a light dispersive module coupled to and in optical communication with the collection waveguides of the substrate, and comprising an array of elements; and a detector coupled to and in optical communication with the light dispersive module.