Patent ID: 6681133
Filing Date: 2004-01-20
Classification: A61B,G01N

Abstract:
A method for stabilizing a wavelength of light emitted by a diode laser comprising:(a) irradiating a specimen with excitation light from the diode laser; (b) collecting Raman spectra at a positive target wavelength and at a negative target wavelength emitted by the irradiated specimen, wherein the positive target wavelength is associated with an abundant feature in the specimen and wherein the negative target wavelength is associated with a scant feature in the specimen; (c) determining a quantitative difference between the spectra emitted at the positive target wavelength and the spectra emitted at the negative target wavelength; (d) relaying to the diode laser a signal proportional to the determined difference; and (e) regulating the temperature of the diode laser so as to maintain a maximal difference between the spectra emitted at the positive target wavelength and the spectra emitted at the negative target wavelength.