Patent ID: 8124619
Filing Date: 2012-02-28
Classification: A61K,A61P,C07D

Abstract:
1. A compound of formula (I): wherein: m is 2; n is 1; p is 1, 2, 3 or 4; X is oxygen or NR′; Y is oxygen or sulfur; Z is NR′, a covalent bond or a linker species, A; A is selected from the group —CR′ R″—, —CR′ R″—CR′R″—, —CR′═CR′—, and —C wherein when Z is a covalent bond or A, X must be nitrogen; Ar is an unsubstituted or substituted phenyl, pyridinyl, or pyrimidinyl; Cy is an unsubstituted or substituted pyridinyl, and the substituents are selected from the group consisting of alkyl, alkenyl, heterocyclyl, cycloalkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, halo (e.g., F, Cl, Br, or I), —OR′, —NR′R″, —CF r is an integer from 1 to 6 or a pharmaceutically acceptable salt thereof.