Patent ID: 6465437
Filing Date: 2002-10-15
Classification: A61P,C07H

Abstract:
Two polymorphs of (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[[2,6-dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-&agr;-L-ribo-hexopryanosyl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-&bgr;-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one diphosphate having the formula wherein n is 0 to 8 and the polymorphs are selected from the group consisting of:a. a smectic crystalline meso phase of a liquid crystal; and b. a crystalline diphosphate exhibiting the X-ray powder diffraction pattern Peak No.12345678910d space16.212.410.89.06.96.56.25.45.14.9