Patent ID: 8022058
Filing Date: 2011-09-20
Classification: A61P,C07D

Abstract:
1. A compound of formula: wherein, n is 0, 1, or 2; R is located at one or more of positions 6, 7, 8 or 9 on the benzothiazepine ring; each R is independently selected from the group consisting of H, halogen, —OH, —NH R R R R R R R R X is selected from the group consisting of halogen, CN, CO R wherein each acyl, alkenyl, alkoxyl, alkyl, alkylamino, aryl, cycloalkyl, cycloalkylalkyl, heterocyclyl, and heterocyclylalkyl may be substituted with one or more radicals independently selected from the group consisting of halogen, —CN, —N provided that when each R is H and n is 0, then R further provided that when R is H and n is 1 or 2, then R further provided that when R is Me, Cl, CN or F at the 6 position of the benzothiazepine ring, or Br at position 7 of the benzothiazepine ring, then R further provided that when n is 0, and R is H, or OH or C further provided that when R is H, n is 0 or 2; R further provided that when R is methoxy at positions 3 and 4 of the benzene ring, R further provided that when R is H, R further provided that when R further provided that when R, R