Patent ID: 7579373
Filing Date: 2009-08-25
Classification: A61P,C07F

Abstract:
1. A linear polyamine-bridged platinum compound having the general formula [(PtXYZ)-A-(Pt X′Y′Z′)], or salts thereof, where X, Y, Z, X′, Y′, and Z′ may be the same or different and are A is a bridging polyamine having a general formula selected from the group consisting of where B and B′ are hydrogen or a labile blocking group and may be the same or different, and may be the same or different at each location, and where B′ may be present or absent, and wherein when said anionic groups or neutral groups of said linear polyamine-bridged platinum compound are in a 1,1/t,t configuration with respect to said bridging polyamine, said labile blocking group is not tBOC; and wherein with the proviso that when x =4, y =3, and at least two of X, Y, Z and X′, Y′, Z′ are NH