Patent ID: 8956876
Filing Date: 2015-02-17
Classification: C09B,G01N,Y10T

Abstract:
1. A method for quantitatively detecting 8-oxo 2′-deoxyguanosine in an aqueous sample solution, comprising the steps of: 1) immobilizing a fluorescent probe molecule showing a fluorescence response specific to 8-oxo 2′-deoxyguanosine on surfaces of fine particles via a spacer unit and bringing the sample solution into contact with the fine particles; and 2) measuring a physical property of the fine particles before and after the contact with the sample solution to determine a change in the physical property; wherein: the fluorescent probe molecule showing a fluorescence response specific to 8-oxo 2′-deoxyguanosine is a molecule of Formula (1): where: the fine particles are silica gel particles.