Patent ID: 7326791
Filing Date: 2008-02-05
Classification: A61P,C07D

Abstract:
1. A compound of formula Ic wherein: R 1 is a group of formula wherein: R R R 2 is a fluorine, chlorine, or bromine atom, or a methyl, ethyl, trifluoromethyl, or methoxy group; R 4 is a C 1-4 -alkyl group which may be substituted by a fluorine atom, a hydroxy, C 1-3 -alkyloxy, trifluoromethoxy, 2,2,2-trifluoroethyloxy, allyloxy, propargyloxy, mercapto, C 1-4 -alkylsulfanyl, C 1-4 -alkylsulfinyl, C 1-14 -alkylsulfonyl, amino, C 1-3 -alkylcarbonylamino, C 1-3 -alkylsulfonylamino, carboxy, aminocarbonyl, C 1-3 -alkylaminocarbonyl, di-(C 1-3 -alkyl)-aminocarbonyl, or a 4- to 7-membered cycloalkyleneiminocarbonyl group, a phenyl, thiophenyl, phenyl-C 1-3 -alkyl, tetrazolyl-C 1-3 -alkyl, imidazolyl-C 1-3 -alkyl, thiazolyl-C 1-3 -alkyl or thiophenyl-C 1-3 -alkyl group, and R 7 is a chlorine or bromine atom, and the tautomers and the salts thereof.