Patent ID: 7541341
Filing Date: 2009-06-02
Classification: A61P,C07H

Abstract:
1. A glucopyranosyloxybenzylbenzene derivative represented by the general formula: wherein P represents a hydrogen atom or a group forming a prodrug; R 1 represents an amino group, a mono or di(lower alkyl)-substituted amino group, a cyano group, a carbamoyl group, a carbamoyl(lower alkyl) group, a lower alkoxycarbonyl-substituted (lower alkyl) group, a lower alkoxycarbonyl-substituted (lower alkoxy) group, a carboxy(lower alkyl) group, or a carboxy(lower alkoxy) group; R 2 represents a hydrogen atom or a lower alkyl group; R 3 represents a lower alkyl group, a lower alkoxy group, a lower alkylthio group, a lower alkenyloxy group, an aralkyloxy group, a lower alkoxy-substituted (lower alkyl) group, a lower alkoxy-substituted (lower alkoxy) group, a lower alkoxy-substituted (lower alkylthio) group, a carboxy group, a lower alkoxycarbonyl group, a cyano group, an aralkyloxy(lower alkyl) group, a cyano(lower alkyl) group, a carbamoyl group, a carbamoyl(lower alkyl) group, an amino group, a mono or di(lower alkyl)-substituted amino group, a lower alkoxycarbonyl-substituted (lower alkyl) group, a lower alkoxycarbonyl-substituted (lower alkoxy) group, a carboxy(lower alkyl) group, a carboxy(lower alkoxy) group, or a group represented by the general formula: P 2 —O—A 2 — wherein P 2 represents a hydrogen atom or a group forming a prodrug; and A 2 represents a lower alkylene group, a lower alkyleneoxy group, a lower alkylenethio group, or a lower alkenylene group; and with the proviso at least one of P and P 2 represents a group forming a prodrug or a pharmaceutically acceptable salt thereof.