Patent ID: 7220734
Filing Date: 2007-05-22
Classification: A61P,C07D

Abstract:
1. A compound represented by Formula I: or a pharmaceutically acceptable salt or hydrate thereof, wherein: m is 0; p is 1; G is —C(R A is selected from the group consisting of: —CO each R R each R 4 is independently selected from the group consisting of: hydrogen and C 1-4 alkyl, said C 1-4 alkyl optionally substituted from one up to the maximum number of substitutable positions with halo, each R Z is selected from the group consisting of: or Z is not present; when Z is not present then X is selected from the group consisting of: phenyl, C when Z is phenyl or HET phenyl and HET 2 , said phenyl and HET 2 each optionally substituted with 1–3 substituents independently selected from the group consisting of: halo, C 1-4 alkyl and C 1-4 alkoxy, and wherein when X is —C 1-6 alkyl-, —O—C 1-5 alkyl-, —(C═O)—C 1-5 alkyl-, —(C═O)—O—C 1-4 alkyl-, —(C═O)—N(R 6 )(R 7 )—C 1-4 alkyl-, or the point of attachment of the group Z is on the alkyl, and when Z is C R HET