Patent ID: 9051363
Filing Date: 2015-06-09
Classification: A61K,A61P,C07K

Abstract:
1. A method of lessening the severity of Alzheimer's disease in the brain of a patient comprising administering a humanized immunoglobulin that binds to Aβ to a patient having or at risk of the disease thereby lessening the severity of the disease, wherein the humanized antibody comprises: a humanized immunoglobulin light chain comprising (i) three variable region complementarity determining regions (CDRs) from the 3D6 immunoglobulin light chain, a humanized immunoglobulin heavy chain comprising (i) three variable region complementarity determining regions (CDRs) from the 3D6 immunoglobulin heavy chain, wherein 3D6 is an antibody of American Type Culture Collection deposit PTA-5130.