Patent ID: 9174212
Filing Date: 2015-11-03
Classification: B01L,B33Y,C12M,G01N

Abstract:
1. A filtration device including at least one filtration unit, the at least one filtration unit comprising: a first sidewall; a second sidewall; a first fluid inlet defined between the first sidewall and the second sidewall, the first fluid inlet configured to receive a feed comprising a particle population and a fluid; a first row of pillars; a first plurality of pores defined by spacings between adjacent pillars in the first row of pillars; a first flow chamber defined between the first row of pillars and the second sidewall and including a first flow chamber inlet and a first retentate outlet, the first flow chamber configured to direct a first retentate including at least a portion of the particle population to the first retentate outlet; a second flow chamber defined between the first row of pillars and the first sidewall and including a first filtrate outlet, the second flow chamber configured to direct a first filtrate including at least a portion of the fluid to the first filtrate outlet; wherein a distance between the first row of pillars and the first sidewall proximate the first flow chamber inlet is smaller than a distance between the first row of pillars and the first sidewall proximate the first retentate outlet; a second row of pillars; a second plurality of pores defined by spacings between adjacent pillars in the second row of pillars; and a third flow chamber defined between the second row of pillars and the second sidewall, the third flow chamber including a third flow chamber inlet configured to receive the first retentate and the first filtrate and a second retentate outlet, the third flow chamber being configured to direct at least a portion of the particle population to the second retentate outlet, a distance between the second row of pillars and the first sidewall proximate the third flow chamber inlet being smaller than a distance between the third row of pillars and the first sidewall proximate the second retentate outlet.