Patent ID: 7192944
Filing Date: 2007-03-20
Classification: A61P,C07D,Y10S

Abstract:
1. A compound represented by the structural formula (I): or pharmaceutically acceptable isomers, salts, solvates or esters of the compound of Formula (I), wherein in Formula (I) above: X, Y and Z can be the same or different and each is independently selected from the group consisting of —CH Q Q Q Q wherein optionally one or more carbon atoms of the —(C G is selected from the group consisting of a amino acid residue and —S(O) L is selected from the group consisting of wherein Me is methyl; M is selected from the group of moieties consisting of pharmaceutically acceptable salts of the moieties (M1) and (M3) to (M10) and free acids of the moieties (M1) and (M3) to (M10); R R each R each R q is 0 or 1; r is 0 or 1; m, n and p are independently selected from 0, 1, 2, 3 or 4; provided that at least one of q and r is 1, and the sum of m, n, p, q and r is 1, 2, 3, 4, 5 or 6; and provided that when p is 0 and r is 1, the sum of m, q and n is 1, 2, 3, 4 or 5; x1 is 1 to 10; x2 is 1 to 10; x3 is 1 to 10; x4 is 1 to 10; x5 is 1 to 10; x6 is 1 to 10; and x7 is 1 to 10; x8 is 1 to 10; x9 is 1 to 10; x10 is 1 to 10; x11 is 1 to 10; x12 is 1 to 10; x13 is 1 to 10; x14 is 1 to 10; x15 is 1 to 10; and x16 is 1 to 10; x17 is 1 to 10; and x18 is 1 to 10; with the proviso that at least one of Q wherein each of the above alkyl, alkenyl, alkynyl, alkylene, alkoxyalkoxy, alkoxyalkoxyalkoxy, alkoxycarbonylalkoxy, alkoxyarylalkoxy, alkoxyiminoalkyl, alkyldioyl, allyloxy, aryl, arylalkyl, aryloxy, arylalkoxy, aroyl, aroyloxy, aroylaroyloxy, arylalkoxycarbonyl, benzoylbenzoyloxy, heteroaryl, heteroarylalkyl, heteroarylalkoxy, dioxolanyl, heterocyclyl, heterocyclylalkyl, heterocyclylcarbonyl, or heterocyclylcarbonylalkoxy groups, when present, is independently substituted or unsubstituted.