Patent ID: 7897612
Filing Date: 2011-03-01
Classification: A61P,C07D

Abstract:
1. A compound which is: N-{[1-(2-cyclopropylethyl)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]carbonyl}glycine; N-{[4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]carbonyl}glycine; N-{[1-(3,3-dimethylbutyl)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]carbonyl}glycine; N-{[4-hydroxy-2-oxo-1-(phenylmethyl)-1,2-dihydro-1,8-naphthyridin-3-yl]carbonyl}glycine; N-({1-[2-(dimethylamino)ethyl]-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]carbonyl}glycine; N-{[1-(3,3-dimethylbutyl)-4-hydroxy-7-methyl-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]carbonyl}glycine; N-{[6-chloro-1-(3,3-dimethylbutyl)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]carbonyl}glycine; N-{[1-(3,3-dimethylbutyl)-4-hydroxy-2-oxo-7-(trifluoromethyl)-1,2-dihydro-1,8-naphthyridin-3-yl]carbonyl}glycine; N-{[1-(3,3-dimethylbutyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]carbonyl}glycine; N-{[6-bromo-1-(3,3-dimethylbutyl)-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]carbonyl}glycine; N-[(1-{[4-(1,1-dimethylethyl)phenyl]methyl}-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl)carbonyl]glycine; {[6-{[(carboxymethyl)amino]carbonyl}-8-(3,3-dimethylbutyl)-5-hydroxy-2-methyl-7-oxo-7,8-dihydro-1,8-naphthyridin-4-yl]amino}acetic acid; N-[(1-{[4-(1,1-dimethylethyl)phenyl]methyl}-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl)carbonyl]glycine; N-{[1-{[4-(1,1-dimethylethyl)phenyl]methyl}-4-hydroxy-2-oxo-7-(trifluoromethyl)-1,2-dihydro-1,8-naphthyridin-3-yl]carbonyl}glycine; N-({1-[(2-chlorophenyl)methyl]-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl]carbonyl}glycine; or a pharmaceutically acceptable salt thereof.