Patent ID: 8236318
Filing Date: 2012-08-07
Classification: A61K,A61P,C07K

Abstract:
1. A method for targeting an antigen to human DEC-205 in a human subject comprising administering to the human subject an antibody linked to an antigen, wherein the antibody comprises: (a) a heavy chain variable region CDR1 comprising SEQ ID NO: 29; (b) a heavy chain variable region CDR1 comprising SEQ ID NO: 17; (c) a heavy chain variable region CDR1 comprising SEQ ID NO: 5; (d) a heavy chain variable region CDR1 comprising SEQ ID NO: 41; (e) a heavy chain variable region CDR1 comprising SEQ ID NO: 53; (f) a heavy chain variable region CDR1 comprising SEQ ID NO: 77; wherein the antibody binds to human DEC-205 comprising SEQ ID NO:1.