Patent ID: 8710061
Filing Date: 2014-04-29
Classification: A61K,A61P,C07D

Abstract:
1. A compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein A is a nitrile group; B is selected from phenyl and pyridinyl, wherein the phenyl and pyridinyl are optionally substituted with one or two substituents independently selected from C D is selected from the group of: “ “ R R C 1-4 alkoxycarbonyl; and wherein the ring is optionally substituted with one or two substituents independently selected from C 1-6 alkoxy, C 1-6 alkyl, halo, haloC 1-4 alkyl, hydroxy, —NR f R g , oxo, spirocyclic dioxolanyl; wherein R f and R g are independently selected from hydrogen, C 1-4 alkoxycarbonyl, and C 1-6 alkyl; R C 1-4 alkoxy; R E is selected from C