Patent ID: 6509145
Filing Date: 2003-01-21
Classification: A61F,A61L

Abstract:
A method of making a tissue-derived, implantable vascular bioprosthesis, the method comprising:excising tissue from an animal, the excised tissue selected form the group consisting of porcine aortic toot tissue, bovine aortic root tissue, porcine pericardium, bovine pericardium, bovine veins, porcine veins, bovine arteries, and porcine arteries; and removing cell debris from the excised tissue by a method which comprises: contacting the excised tissue with a composition comprising at least on oxidizing agent prior to significant degradation of the excised tissue; and rinsing the oxidizing agent-contacted tissue to remove at least a portion of the oxidizing agent, wherein the oxidizing agent is selected from the group of sodium hypochlorite, performic acid, periodic acid, peracetic acid, and combinations thereof.