Patent ID: 6663898
Filing Date: 2003-12-16
Classification: A61K,A61P,C07C,Y10S

Abstract:
A delivery composition comprising:(a) a peptide; and (b) at least one diketopiperazine having the formula: wherein R1 and R2 are C1-C24 alkyl or C1-C24 alkenyl and have at least one functional group selected from the group consisting of oxygen and amide groups; both R1 and R2, optionally, are substituted with C1-C4 alkyl, C1-C4 alkenyl, C1-C4 alkoxy, â€”OH, â€”SH, and â€”CO2R3 or any combination thereof; wherein R3 is hydrogen, C1-C4 alkyl, or C1-C4 alkenyl; R1 and R2 are interrupted by oxygen, nitrogen, sulfur, or any combination thereof.