Patent ID: 6262230
Filing Date: 2001-07-17
Classification: A61K,A61P,C07K

Abstract:
A compound of the formula:X-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser- (I)Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Zwherein X is an acetyl or pyroglutamyl group and Z is --NH.sub.2, -Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-Pro-NH.sub.2, -Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-Gly-NH.sub.2, or -Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn with the proviso that when X is a pyroglutamyl group, Z is -Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn, and when X is an acetyl group, Z is other than -Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn.