Patent ID: 9157102
Filing Date: 2015-10-13
Classification: C12N,C12P,C12Y,Y02E

Abstract:
1. An isolated bacterial, fungal or yeast cell having increased NADH-dependent propanediol oxidoreductase (FucO) activity as compared to a reference bacterial, fungal or yeast cell, wherein said bacterial, fungal or yeast cell having increased FucO activity reduces furfural and/or 5-hydroxymethylfurfural (5-HMF) to their respective alcohols and wherein the isolated bacterial, fungal or yeast cell also comprises modification to a yqhD gene, a yqhC gene and/or a dkgA gene which causes decreased activity of a YqhD protein, decreased activity of a YqhC protein and/or decreased activity of a DkgA protein in the cell compared to the reference bacterial, fungal or yeast cell.