Patent ID: 9211274
Filing Date: 2015-12-15
Classification: A61K,A61P

Abstract:
1. An implantable device for reducing or treating pain in a patient in need of such treatment, the implantable device comprising a transient receptor potential cation channel subfamily V member 1 (TRPV1) compound comprising a capsaicinoid compound in an amount of about 55 wt. % of the implantable device, and at least one biodegradable polymer, wherein the implantable device is capable of releasing the TRPV 1 compound over a period of at least three days, wherein the at least one biodegradable polymer comprises collagen in sponge matrix form that is soaked or sprayed with the compound, and the collagen sponge comprises a burst surface on edges of the collagen sponge that release about 35% of the TRPV1 compound over 24 hours, and the sponge matrix has a porosity of at least about 70%.