Patent ID: 6617453
Filing Date: 2003-09-09
Classification: C07D,C09B

Abstract:
A process for preparing a triphendioxazine compound of formula I in which rings labeled A having positions 1,2-, 2,3- or 3,4- and 8,9-, 9,10- or 10,11-, carry a single chain linkage linking such positions, the single chain linkage having a formula selected from the group consisting of â€”NR5â€”(CO)mâ€”NHâ€”, â€”CR5&boxH;CHâ€”COâ€”NH, â€”COâ€”CH2â€”COâ€”NH, â€”COâ€”CH&boxH;CR5â€”NH, â€”COâ€”NHâ€”COâ€”NH, â€”COâ€”NHâ€”CR6&boxH;N, â€”CR6&boxH;Nâ€”COâ€”NH, â€”NR5â€”(CO)mâ€”O and â€”NHâ€”CR5&boxH;Nâ€”â€ƒwherein R5 is hydrogen, C1-4 alkyl or phenyl; R6 is hydrogen, C1-4 alkyl or phenyl; and m is 1 or 2, provided that in a symmetrically disubstituted compound the definitions hydrogen, C1-2alkyl or unsubstituted phenyl are excluded, the process comprising reacting two moles of a compound of formula IV â€ƒin which ring A carries in two corresponding positions the single chain as defined above, with one mole of 2,3,5,6-tetrachloro-1,4-benzoquinone (chloranil) and cyclizing the compound of formula XVII to the compound of the formula I in the presence of manganese dioxide and concentrated sulphuric acid.