Patent ID: 6074663
Filing Date: 2000-06-13
Classification: A61F,A61L,A61P

Abstract:
A method of using a self-supporting film material of cross-linked fibrin for the preparation of a medicament for the prevention of adhesion formation as a post-operative complication, comprising the step of applying the film material of cross-linked fibrin to an injured surface, wherein the film material of cross-linked fibrin is prepared by the steps comprising:(a) converting fibrinogen to fibrin using a thrombin-containing solution having a concentration of at least 20 IU/ml;(b) converting the fibrinogen such that the conversion to fibrin is substantially complete in that there is essentially no unreacted fibrinogen in the fibrin material; and(c) forming a fibrin material having a pore size of below 5 .mu.m.