Patent ID: 6319916
Filing Date: 2001-11-20
Classification: C07D

Abstract:
A compound of the formula: ##STR597##wherein ring A is an unsubstituted benzene ring or a substituted benzene ring,wherein said substituted benzene ring is substituted with 1 to 3 substituents selected from the group consisting of a C.sub.1-4 alkyl group, a halogen atom, a nitro group, a cyano group, a hydroxyl group, a C.sub.1-4 alkoxy group, a C.sub.1-4 alkoxy group C.sub.1-4 alkylthio group, an amino group, a mono- or di-C.sub.1-4 alkylamino group, a 5- to 7-membered cyclic amino group which may have, other than carbon atoms and one nitrogen atom, 1 to 3 hetero atoms selected from the group consisting of nitrogen, oxygen and sulfur atoms, a C.sub.1-4 alkyl-carbonylamino group, an aminocarbonyloxy group, a mono- or di-C.sub.1-4 alkylamino-carbonyloxy group, a C.sub.1-4 alkylsulfonylamino group, a C.sub.1-4 alkoxy-carbonyl group, a carboxyl group, a C.sub.1-6 alkyl-carbonyl group, a C.sub.3-7 cycloalkyl-carbonyl group, a carbamoyl group, a mono- or di-C.sub.1-4 alkyl-carbamoyl group, a C.sub.1-6 alkylsulfonyl group, a C.sub.3-7 cycloalkylsulfonyl group, phenyl group, naphthyl group, a mono- or di-phenyl-C.sub.1-3 alkyl group, a phenoxy group, a benzoyl group, a phenoxycarbonyl group, a benzylcarbonyl group, a phenyl-C.sub.1-4 alkyl-carbamoyl group, a phenylcarbamoyl group, a phenyl-C.sub.1-4 alkyl-carbonylamino, benzoylamino group, a phenyl-C.sub.1-4 alkylsulfonyl group, a phenylsulfonyl group, a phenyl-C.sub.1-4 alkylsulfinyl group, a phenyl-C.sub.1-4 alkylsulfonylamino group and a phenylsulfonylamino group,wherein each phenyl group or naphthyl group in the substituents may be substituted with 1 to 4 substituents selected from the group consisting of a C.sub.1-4 alkyl group, a C.sub.1-4 alkoxy group, a halogen atom, a hydroxyl group, a benzyloxy group, an amino group, a mono- or di-C.sub.1-4 alkylamino group, a nitro group, a C.sub.1-6 alkyl-carbonyl group and a benzoyl group;ring B' is a non-aromatic heterocyclic ring represented by the following formulae: ##STR598##wherein R.sup.6 is (1) a hydrogen atom, (2) a C.sub.1-7 alkyl or a C.sub.7-10 aralkyl group which may be substituted with a C.sub.1-4 alkyl group, a halogen atom, a nitro group, a C.sub.1-4 alkoxy group or a hydroxyl group, (3) a formyl group or (4) a C.sub.2-8 alkylcarbonyl group;R' is a hydrogen atom,an unsubstituted hydrocarbon group or a substituted hydrocarbon group, which may be different from one another in the repetition of n,wherein said substituted hydrocarbon group is substituted with 1 to 5 substituents selected from the group consisting of a halogen atom, a nitro group, a cyano group, a hydroxyl group, a C.sub.1-4 alkoxy group, a C.sub.1-4 alkylthio group, an amino group, a mono- or di-C.sub.1-4 alkylamino group, a 5- to 7-membered cyclic amino group which may have, other than carbon atoms and one nitrogen atom, 1 to 3 hetero atoms selected from the group consisting of nitrogen, oxygen and sulfur atoms, a C.sub.1-4 alkyl-carbonylamino group, a C.sub.1-4 alkylsulfonylamino group, a C.sub.1-4 alkoxy-carbonyl group, a carboxyl group, a C.sub.1-6 alkyl-carbonyl group, a carbamoyl group, a mono- or di-C.sub.1-4 alykl-carbamoyl group, a C.sub.1-6 alkylsulfonyl group, a C.sub.1-4 alkyl group, an aminocarbonyloxy group, a mono- or di-C.sub.1-4 alkylamino-carbonyloxy group, a C.sub.3-7 cycloalkyl-carbonyl group, a C.sub.3-7 cycloalkylsulfonyl group, phenyl group, naphthyl group, a mono- or di-phenyl-C.sub.1-3 alkyl group, a phenoxy group, a benzoyl group, a phenoxycarbonyl group, a benzylcarbonyl group, a phenyl-C.sub.1-4 alkyl-carbamoyl group, a phenylcarbamoyl group, a phenyl-C.sub.1-4 alkyl-carbonylamino, benzoylamino group, a phenyl-C.sub.1-4 alkylsulfonyl group, a phenylsulfonyl group, a phenyl-C.sub.1-4 alkylsulfinyl group, a phenyl-C.sub.1-4 alkylsulfonylamino group and a phenylsulfonylamino group,wherein each phenyl group or naphthyl group in the substituents may be substituted with 1 to 4 substituents selected from the group consisting of a C.sub.1-4 alkyl group, a C.sub.1-4 alkoxy group, a halogen atom, a hydroxyl group, a benzyloxy group, an amino group, a mono- or di-C.sub.1-4 alkylamino group, a nitro group, a C.sub.1-6 alkyl-carbonyl group and a benzoyl group;Y is an unsubstituted amino group, a substituted amino group, an unsubstituted N-containing saturated heterocyclic group, or a substituted N-containing saturated heterocyclic group,wherein said substituted amino group is substituted with 1 to 2 substituents selected from the group consisting of a hydrogen atom, an unsubstituted hydrocarbon group, said substituted hydrocarbon group of R.sup.1, an unsubstituted acyl group and a substituted acyl group,wherein said substituted acyl group is substituted with 1 to 3 substituents selected from the group consisting of a halogen atom, a nitro group, a hydroxy group, an amino group, a mono- or di-C.sub.1-6 alkylamino group and a C.sub.1-4 alkoxy group, andsaid substituted N-containing saturated heterocyclic group is substituted with 1 to 5 substituents selected from the group consisting of an unsubstituted hydrocarbon group, said substituted hydrocarbon group of R.sup.1, an unsubstituted acyl group, said substituted acyl group for said substituted amino group of Y, a halogen atom, a nitro group, a cyano group, an oxo group, a hydroxyl group, a C.sub.1-4 alkoxy group, a C.sub.1-4 alkylthio group, an amino group, a mono- or di-C.sub.1-4 alkylamino group, a 5- to 7-membered cyclic amino group which may have, other than carbon atoms and one nitrogen atom, 1 to 3 of hetero atoms selected from the group consisting of nitrogen, oxygen and sulfur atoms, a C.sub.1-4 alkyl-carbonylamino group, a C.sub.1-4 alkylsulfonylamino group, a C.sub.1-4 alkoxy-carbonyl group a phenyl-C.sub.1-4 alkyl-oxycarbonyl group, a carboxyl group, a C.sub.1-6 alkyl-carbonyl group, benzoyl group, a substituted benzoyl group, a carbamoyl group, a mono- or di-C.sub.1-4 alkyl-carbamoyl group and a C.sub.1-6 alkylsulfonyl groupwherein said substituted benzoyl group is substituted with 1 to 3 substituents selected from the group consisting of a C.sub.1-4 alkyl group, a halogen atom, a C.sub.1-4 alkoxy group, a mono- or di-C.sub.1-4 alkylamine, a 5- to 7-membered cyclic amino group, a nitro group and a hydroxyl group; andn denotes an integer of 2; or a salt thereof.