Patent ID: 6420123
Filing Date: 2002-07-16
Classification: B01J,C07K,C40B

Abstract:
A method for the solid support synthesis of combinatorial libraries using a split technique comprising the steps of:a. forming at least two strings of solid support units comprising a sequence of spatially arranged solid support units secured by a retainer for maintaining the sequential arrangement of said support units in said strings, said support units having surface for coupling a first product segment; b. converting said strings to source strings by coupling a first product segment on the support units of said source strings, the first product segment on each of the source strings being different; c. transferring said support units in a predetermined pattern from each source string to destination string retainers to form a corresponding number of destination strings in which the support units from said source strings are disposed in a new sequential arrangement on said destination strings; d. determining the sequential position of each of said support units on said destination strings; whereby the position history of each support unit allows the structure of each product produced on each support unit to be predicted and the need for labels is eliminated.