Patent ID: 9018439
Filing Date: 2015-04-28
Classification: A01K,C07K,C12N

Abstract:
1. A method for producing a transgenic pig, comprising: a) isolating somatic cells from a pig; b) introducing a gene coding for human HO-1 (Heme oxygenase-1) protein and a gene coding for human TNFR1-Fc (Tumor necrosis factor receptor 1-Fc) fusion protein into the somatic cells; c) selecting the somatic cells that are introduced with the genes; d) removing the nucleus from an oocyte of the pig and fusing it with the selected somatic cell to prepare a somatic cell nuclear transferred embryo; and e) implanting the embryo, wherein an organ of the transgenic pig is suppressed in immune rejection response during organ xenotransplantation.