Patent ID: 8334290
Filing Date: 2012-12-18
Classification: A61P,C07D

Abstract:
1. A compound having Formula Ia, or a pharmaceutically acceptable salt thereof, wherein R R R x is an integer from 0-2; B is selected from the group consisting of: —N(R —N(R —N(R —N(R —N(R —N(R —N(R —N(R —OD —SD —C(═O)CH -D -D D D is a difunctional group selected from C D R R T is selected from —O—, —N(R Each R R (a) C (b) Bicyclic C (c) A 4-8 membered saturated or partly unsaturated heterocyclic ring having 1-2 ring members independently selected from —O— and —N(R (d) An aromatic ring selected from phenyl and naphthyl; and (e) A 5-7 membered heteroaromatic ring having 1-3 heteroatoms independently selected from N, S, and O, and optionally having one —C(═O)— group as a ring member, said heteroaromatic ring being connected to the left hand part of formula I through a carbon atom of the heteroaromatic ring, wherein said heteroromatic group is optionally fused to an aromatic ring selected from phenyl and naphthyl; Wherein said cyclic groups R R R R With the proviso (I) that when the group R And with the further proviso (II) that when the group R