Patent ID: 6949662
Filing Date: 2005-09-27
Classification: A61K,A61P,C07D,Y02A

Abstract:
1. A compound represented by formula (VI): wherein R 1 and R 2 each independently represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms which may be substituted with one or more substituents selected from the group consisting of a hydroxyl group, a halogen atom, an alkylthio group having 1 to 6 carbon atoms, and an alkyloxy group having 1 to 6 carbon atoms; one of R 1 and R 2 may be a protective group for amino group selected from the group consisting of an alkoxylcarbonyl group, an aralkyloxycarbonyl group, an acyl group having 2 to 5 carbon atoms, an alkyl group, an aralkyl group which is a benzyl group, and a silyl group that is substituted with an alkyl or phenyl group; n represents an integer of 2; Q′ represents a hydrogen atom or a protective group for amino group selected from the group consisting of an alkoxylcarbonyl group, an aralkyloxycarbonyl group, an acyl group having 2 to 5 carbon atoms, an alkyl group, an aralkyl group which is a benzyl group, and a silyl group that is substituted with an alkyl or phenyl group; and the two substituents on the cyclopropane ring, are in a cis-configuration; or a salt or hydrate thereof or a hydrate of the salt or a stereochemically pure isomeric form thereof.