Patent ID: 8158577
Filing Date: 2012-04-17
Classification: A61K,A61P,C07K

Abstract:
1. A composition for the treatment of a disease associated with inflammatory mediated cartilage destruction consisting of: a linear or cyclic compound consisting of the formula 1 wherein X1 is x is selected from C or absent X2 is selected from Q or absent X3 is selected from L or absent X4 is selected from R, C or absent X5 is selected from G, K or absent X6 is selected from L, F or absent X7 is selected from R, P or absent X8 is selected from R, C, T or absent Y1 is selected from A, C or absent Y2 is selected from S, G or absent Y3 is selected from R or absent Y4 is selected from P, H or absent Y5 is selected from D or absent Y6 is selected from A or absent Y7 is selected from T or absent Y8 is selected from C or absent and P1 and P2 are absent or a protective group, together with one or more adjuvants, carriers or excipients.