Patent ID: 6812362
Filing Date: 2004-11-02
Classification: A61P,C07C

Abstract:
A method for synthesizing a compound having the structure of Formula III: wherein R1, R2, R3, and R4 are defined as below, comprising:contacting a compound having the structure of Formula I: whereinR1 is substituted or unsubstituted alkyl or haloalkyl, with a compound having the structure of Formula II: whereinR2 is cyano, carbamoyl, nitro, fluoro, chloro, bromo, iodo, or hydrogen; or alkyl, alkoxy, alkanoyl, alkylthio, alkylsulfinyl, or alkylsulfonyl each being substituted or unsubstituted and having up to 4 carbon atoms; or phenyl, phenylthio, phenylsulfinyl or phenylsulfonyl each being substituted or unsubstituted; R3 is cyano, carbamoyl, nitro, fluoro, chloro, bromo or iodo; or alkyl, alkoxy, alkanoyl, alkylthio, alkylsulfinyl, or alkylsulfonyl each being substituted or unsubstituted and having up to 4 carbon atoms; or phenyl, phenylthio, phenylsulfinyl or phenylsulfonyl each being substituted or unsubstituted; and R4 is hydrogen or halogen; under conditions sufficient to provide a compound having the structure of Formula III.