Patent ID: 7700631
Filing Date: 2010-04-20
Classification: A61P,C07D

Abstract:
1. A method for treating rheumatoid arthritis in a patient, said method comprising administering to said patient an effective amount of a compound of Formulas I-III: wherein one of A, B and D is N—O and the others are CR R R R R L is a single bond or a divalent aliphatic radical having 1 to 8 carbon atoms wherein one or more —CH R arylalkyl having 7 to 19 carbon atoms, wherein the aryl portion has 6 to 14 carbon atoms and the alkyl portion, which is branched or unbranched, has 1 to 5 carbon atoms, wherein the arylalkyl radical is unsubstituted or substituted, in the aryl portion, one or more times by halogen, trifluoromethyl, CF R R R R R R R R X and Y are each independently O or S; and G is alkylene having 2 to 7 carbon atoms which is unsubstituted or substituted one or more times by halogen; or a pharmaceutically acceptable salt thereof; wherein an optically active compound can be in the form of one of its separate enantiomers or mixtures thereof, including racemic mixtures.