Patent ID: 7811811
Filing Date: 2010-10-12
Classification: G01N,Y10T

Abstract:
1. A flow channel module for use in a device for detecting the presence of a ligand in a sample, comprising: a first chamber comprising in its interior a composition which exhibits specificity for a ligand, wherein the composition comprises at least one member selected from the group consisting of a microparticle and a receptor; a second chamber comprising in its interior a liquid crystalline material; a detection chamber delineated on at least two opposing sides by a low or non birefringent transparent plate, wherein one or more surfaces of the low or non birefringent plate has longitudinal microgrooves oriented along an axis that is parallel to the direction of flow into the detection chamber; and an inlet port; wherein the first chamber, the second chamber, and the detection chamber are arranged in series, and wherein the inlet port is in fluid communication with the first chamber, the first chamber is in fluid communication with the second chamber, and the second chamber is in fluid communication with the detection chamber.