Patent ID: 7996157
Filing Date: 2011-08-09
Classification: G16B,Y02A

Abstract:
1. A method of selecting one or more polymorphisms from a genomic region of interest for use in genotyping, comprising the steps of: a. obtaining a sequence polymorphism cluster (SPC) map using a computer-implemented method of producing a map of a genomic region of interest, said map on a computer comprising one or more sequence polymorphism clusters (SPCs), wherein each SPC comprises a subset of polymorphisms from said genomic region wherein said polymorphisms of said subset co-segregates with each other polymorphism of said subset; and wherein said map further comprises non-co-segregating polymorphisms that are associated with the map, wherein said non-co-segregating polymorphisms are such that they do not co-segregate with any other polymorphism but do co-segregate with at least one SPC, said computer-implemented method comprising the steps of: b. selecting on a computer at least one cluster tag polymorphism which identifies a specific SPC in said SPC map; and c. selecting on a computer a a plurality of cluster tag polymorphisms to genotype the SPCs in the genomic region of interest.