Patent ID: 7649110
Filing Date: 2010-01-19
Classification: A61P,C07D

Abstract:
1. A compound having the formula (I): or a pharmaceutically acceptable salt thereof, wherein Q is a phenyl; L P is a phenyl; L M is a phenyl; X is CR L A is —CO R R R R R optionally, R R optionally, R R the subscript m is 0, 1 or 2; and the subscript p is 1 or 2; wherein the phenyl, aryl, and heteroaryl groups set forth above are optionally substituted with substituents selected from -halogen, —OR′, —OC(O)R′, —NR′R″, —SR′, —R′, —CN, —NO 2 , —CO 2 R′, —CONR′R″, —C(O)R′, —OC(O)NR′R″, —NR″C(O)R′, —NR″C(O) 2 R′, —NR′—C(O)NR″R′″, —NH—C(NH 2 )═NH, —NR′C(NH 2 )═NH, —NH—C(NH 2 )═NR′, —S(O)R′, —S(O) 2 R′, —S(O) 2 NR′R″, —N 3 , —CH(Ph) 2 , perfluoro(C 1 -C 4 )alkoxy, and perfluoro(C 1 -C 4 )alkyl, in a number ranging from zero to the total number of open valences on the phenyl, aryl, or heteroaryl ring system; and further wherein R′, R″ and R′″ are independently selected from hydrogen, (C 1 -C 8 )alkyl and heteroalkyl, unsubstituted aryl and heteroaryl, (unsubstituted aryl)-(C 1 -C 4 )alkyl, and (unsubstituted aryl)oxy-(C 1 -C 4 )alkyl.