Patent ID: 7041782
Filing Date: 2006-05-09
Classification: A01K,C07K

Abstract:
1. A method for screening for inhibitors of binding between an ss3939 polypeptide and a binding partner of said ss3939 polypeptide, the method comprising: a) providing an isolated soluble ss3939 polypeptide comprising the amino acid sequence selected from the group consisting of amino acids 22 through 227 of SEQ ID NO:2, amino acids 24 through 227 of SEQ ID NO:2, and amino acids 25 through 227 of SEQ ID NO:2; b) bringing said isolated soluble ss3939 polypeptide into contact with human umbilical vein endothelial cells in the presence of and in the absence of a test compound, wherein the binding partner of said ss3939 polypeptide is expressed by human umbilical vein endothelial cells, and wherein said isolated soluble ss3939 polypeptide binds to human umbilical vein endothelial cells; and c) determining if the binding of ss3939 to the human umbilical vein endothelial cells is inhibited by the test compound.