Patent ID: 6448081
Filing Date: 2002-09-10
Classification: A61K,C12N,Y02P

Abstract:
A compound 20 to 50 nucleobases in length targeted to a start codon region, nucleobases 72 through 100, nucleobases 216 through 281, nucleobases 305 through 321, nucleobases 400 through 419, nucleobases 450 through 469, nucleobases 790 through 809, nucleobases 967 through 986 of a coding region, a stop codon region or a 3â€²-untranslated region of a nucleic acid molecule encoding human Interleukin 12 p40 subunit of SEQ ID NO: 3, wherein said compound specifically hybridizes with one of said regions and inhibits the expression of human Interleukin 12 p40 subunit.