Patent ID: 7521475
Filing Date: 2009-04-21
Classification: A61P,C07D

Abstract:
1. A composition comprising a therapeutically effective amount of (i) at least one substantially purified compound of the formula: wherein: R R R wherein the R 9a substituents are the same or different and each is R 11 , C(O)R 11 , or SO 2 R 11 , wherein R 11 is H, a straight-chain or branched C 1-30 saturated alkyl, a straight-chain or branched C 2-30 unsaturated alkyl, or an aryl comprising 6-10 carbon atoms in the ring skeleton thereof wherein R 11 is unsubstituted or substituted with one or more substituents, which are the same or different, selected from the group consisting of a halogen, an oxo, OR 11a , CO 2 R 11a and OC(O)R 11a , wherein R 11a is H, a straight-chain or branched C 1-30 saturated alkyl, a straight-chain or branched C 2-30 unsaturated alkyl, or an aryl comprising 6-10 carbon atoms in the ring skeleton thereof; wherein R (ii) at least one additional therapeutic agent, and (iii) a pharmaceutically acceptable carrier.