Patent ID: 8399454
Filing Date: 2013-03-19
Classification: A61P,C07D

Abstract:
1. A compound of Formula (I) wherein i) C ii) heteroaryl selected from the group consisting of thiazolyl, pyridinyl, indolyl, benzoxazolyl, benzothiazolyl, benzothienyl, benzofuranyl, imidazo[1,2-a]pyridin-2-yl, quinolinyl, thienyl, and benzimidazolyl; iii) benzofused heterocyclyl attached via a carbon atom, and when the heterocyclyl portion contains a nitrogen atom, the nitrogen atom is optionally substituted with one substituent selected from the group consisting of C iv) 9-methyl-9H-carbazol-3-yl; or v) 6,7,8,9-tetrahydro-5H-carbazol-3-yl; wherein C i) C ii) C iii) C iv) C v) C vi) trifluoromethyl; vii) trifluoromethoxy; viii) trifluoromethylthio; ix) chloro; x) cyano; xi) fluoro; xii) bromo; xiii) iodo; xiv) NR xv) (1-R xvi) a 5 to 8 membered heterocyclyl bound through a carbon atom, wherein when the heterocyclyl contains a nitrogen atom, the nitrogen atom is optionally substituted with C xvii) pyridinyloxy optionally independently substituted with one to two substituents selected from the group consisting of C xviii) phenylsulfonyl optionally substituted with C xix) phenyloxy optionally substituted with one to two substituents selected from the group consisting of C xx) phenylthio optionally substituted with C xxi) C and enantiomers, diastereomers, and pharmaceutically acceptable salts thereof.