Patent ID: 7563920
Filing Date: 2009-07-21
Classification: A61K,C07C,C07D

Abstract:
1. A formulation including tetrakis(2-methoxyisobutylisonitrile)copper(I) tetrafluoroborate, sodium citrate dihydrate, L-cysteine hydrochloride monohydrate, mannitol, and stannous chloride dihydrate under an inert gas in a lyophilized vial, wherein the tetrakis(2-methoxyisobutylisonitrile)copper(I) tetrafluoroborate is sufficiently pure so that when the formulation is (i) reconstituted with sodium pertechnetate ( 99m Tc) for injection in saline obtained from the elution of a 99 Mo/ 99m Tc generator and (ii) heated to form 99m Tc-Sestamibi, the 99m TcSestamibi contains no quantifiable amount of 99m Tc-pentamibi dimethylvinyl isonitrile.