Patent ID: 6353028
Filing Date: 2002-03-05
Classification: A61K,A61P,Y10S

Abstract:
A method for treating a connective tissue disorder selected from the group consisting of Peyronie's disease, Dupuytren's hand contracture and Ledederhose Fibrosis, each disorder manifesting sub-dermal plaque accumulations or scar tissue, wherein the method consists of non-invasive transdermal application of a topical gel composition to a portion of dermis which overlies the sub-dermal plaque or scar tissue, said composition consisting essentially of (i) a calcium channel blocker selected from the group consisting of verapamil, nifedipine, diltiazem, amalodipine, felodipine, isradipine, nicardipine, nimodipine, nisoldipine, bepridil and mixtures thereof; and (ii) a non-invasive transdermal carrier agent.