Patent ID: 7015005
Filing Date: 2006-03-21
Classification: G01N

Abstract:
1. A method for measuring the amount of non-complexed prostate specific antigen (PSA) in a sample from a male human patient comprising: a) adding a specific binding immuno-precipitating reagent to said sample in a solution in an amount sufficient to bind and precipitate any α1-antichymotrypsin (ACT) present in the sample, whether complexed with PSA (PSA-ACT complex) or not; wherein the immuno-precipitating reagent binds either to the ACT or the ACT portion of the PSA-ACT complex but not to non complexed PSA, and the combination of either ACT or PSA-ACT complex and the immuno-precipitating reagent is of a sufficient mass to precipitate out of solution; and b) measuring the amount of non-complexed PSA, which remains in solution, by using an antibody that recognizes PSA in a specific binding reaction, wherein the immuno-precipitating reagent is added to the solution as part of an assay component for measuring non-complexed PSA.