Patent ID: 7829140
Filing Date: 2010-11-09
Classification: A61K,B01J,B82Y,C01G,C01P,C09C

Abstract:
1. A method of making mono-disperse iron oxide core metal shell (core/shell) nanoparticles comprising the steps of: a) reacting a suitable precursor compound of a superparamagnetic core material with one or more reactants in a solution containing first capping agents and a first solvent, thereby producing capped nanoparticle seeds in suspension; b) reacting the capped nanoparticle seeds in suspension with suitable metal precursor compounds and second capping agents in a second organic solvent, thereby producing polydisperse core/shell nanoparticles comprising a coarse fraction and a fine fraction; c) segregating a coarse fraction of the polydisperse core/shell nanoparticles and removing the coarse fraction in a first sizing operation; and d) further sizing the fine fraction, in a second sizing operation, to thereby produce mono-disperse core/shell nanoparticles.