Patent ID: 6897233
Filing Date: 2005-05-24
Classification: A61P,C07D

Abstract:
1. A compound according to formula (1): wherein: R1 is selected from the group consisting of C R2 is selected from the group consisting of hydrogen, C R3 is selected from the group consisting of C R4 is hydrogen, or C R5 and R6 are independently selected from the group consisting of hydrogen, C R7 is selected from the group consisting of hydrogen, and C Ar is selected from the group consisting of phenyl, furyl, and thienyl, all of which may be optionally substituted by one or more Z Ar′ is selected from the group consisting of phenyl, naphthyl, furyl, pyridyl, thienyl, thiazolyl, isothiazolyl, pyrazolyl, triazolyl, tetrazolyl, imidazolyl, imidazolidinyl, benzofuranyl, indolyl, thiazolidinyl, isoxazolyl, oxadiazolyl, thiadiazolyl, morpholinyl, piperidinyl, piperazinyl, pyrrolyl, and pyrimidyl, all of which may be optionally substituted by one or more Z Het is selected from the group consisting of tetrahydrofuranyl and piperidinyl; Z Z —(CH m is 2 to 5; and n is 0 to 5.