Patent ID: 6830890
Filing Date: 2004-12-14
Classification: B01J,C07B,C07H,C07K,C12N,C12Q,C40B,G01N

Abstract:
A method of screening a sample for a species capable of binding to a double-stranded nucleic acid comprising:contacting said sample with a solid support comprising a plurality of different unimolecular double-stranded nucleic acids attached to known locations of the support, each of said attached nucleic acids independently having the formula: -X11-L-X12 wherein, X11 and X12 are complementary nucleic acids; and L is a linking group having sufficient length such that X11 and X12 form said attached unimolecular, double-stranded nucleic acid, to produce at least one bound pair comprising said species and one of said attached unimolecular, double-stranded nucleic acids; and identifying said bound pair.