Patent ID: 6509480
Filing Date: 2003-01-21
Classification: A61K

Abstract:
A compound which is:2&agr;-propanoyloxy-5,7,8&agr;H-eudesma-4(15),11(13)-dien-8,12-olide; 2&agr;-benzoyloxy-5,7,8&agr;H-eudesma-4(15),11(13)-dien-8,12-olide; 2&agr;-furoyloxy-5,7,8&agr;H-eudesma-4(15),11(13)-dien-8,12-olide; 2&agr;-cyclopropanoyloxy-5,7,8&agr;H-eudesma-4(15),11(13)-dien-8,12-olide; 2&agr;-isobutyryloxy-5,7,8&agr;H-eudesma-4(15),11(13)-dien-8,12-olide; 2&agr;-cyclopropanoyloxy-5,7,8,11&agr;H-eudesm-4(15)-en-8,12-olide; 2&agr;-benzoyloxy-5,7,8,11&agr;H-eudesm-4(15)-en-8,12-olide; 2&agr;-benzoyloxy-4,5,7,8,11&agr;H-eudesman-8,12-olide; 2&agr;-acetoxy-4,5,7,8,11&agr;H-eudesman-8,12-olide; 2&agr;-benzoyl-8&bgr;-hydroxy-2&bgr;,4,5,7,8,11&agr;H-eudesaman-12-oic acid; 8&bgr;-hydroxy-4,5,7,8,11&agr;H-eudesman-12-oic acid; sodium 8&bgr;-hydroxy-5,7,8&agr;H-eudesma-4(15),11(13)-dien-12-oate; 1-[2&agr;-hydroxy-11,12-dihydro-5,7,8&agr;H-eudesm-4(15)-en-8,12-olidyl]-pyrrolidine; 8&bgr;-hydroxy-4,7,8&agr;H-eudesama-5,11(13)-dien-12-oic acid; 8&bgr;-hydroxy-5,7,8,11&agr;H-eudesam-4(15)-en-12-oic acid; 2&agr;,8&bgr;-dihydroxy-2&bgr;-4,5,7,8,11&agr;H-eudesaman-12-oic acid; 2&agr;,8&bgr;-dihydroxy-4(15)11(13)-eudesamadien-12-oic acid; or a pharmaceutically acceptable salt thereof.