Patent ID: 6265439
Filing Date: 2001-07-24
Classification: C07C

Abstract:
A compound of Formula I: ##STR35##wherein each of U and V is independently selected from divalent alkyl, divalent alkenylalkyl and divalent alkynylalkyl;wherein R.sup.1 is selected from hydrido, alkyl, hydroxyalkyl, cycloalkyl, cycloalkylalkyl, aralkyl, aryl, aroylalkyl, alkoxyalkyl, alkylcarbonylalkyl, alkoxycarbonylalkyl, alkylaryloxycarbonylalkyl, alkenylalkyl, cycloalkenyl, aralkoxycarbonylalkyl, alkynylalkyl, alkylthiocarbonylalkyl, alkylthiothiocarbonylalkyl, arylthiocarbonylalkyl, arylthiothiocarborylalkyl, aralkylthiocarbonylalkyl, alkylarylthiocarbonylalkyl, alkylsulfonylalkyl, aralkylsulfonylalkyl and arylsulfonylalkyl;wherein R.sup.2 is selected from hydrido, alkyl, hydroxyalkyl, cycloalkyl, cycloalkylalkyl, aralkyl, aroyl, aryloxyalkyl, alkoxyalkyl, alkylcarbonyl, alkylcarbonylalkyl, alkoxycarbonyl, alkenylalkyl, cycloalkenylalkyl, alkynylalkyl, carboxyalkyl, alkylcarbonyloxyalkyl, alkoxycarbonylalkyl, aralkoxycarbonylalkyl, aralkylcarbonyloxyalkyl, mercaptocarbonyl, mercaptothiocarbonyl, mercaptoalkyl, alkylthiocarbonyl, alkylthiothiocarbonyl, arylthiocarbonyl, arylcarbonylthio, arylthiocarbonyloxy, arylthiothiocarbonyl, aralkylthiocarbonyl, alkylthiocarbonylalkyl, alkylsulfinyl, alkylsulfonylalkyl, aralkylsulfinylalkyl, aralkylsulfonylalkyl, arylsulfinylalkyl and arylsulfonylalkyl;wherein each of R.sup.3, through R.sup.12 is independently selected from hydrido, hydroxy, alkyl, hydroxalkyl, halo, haloalkyl, halocycloalkyl, cycloalkyl, cycloalkylalkyl, cycloalkyloxy, formyl, alkoxy, aralkyl, aryl, aroyl, aryloxy, aryloxyalkyl, aralkoxy, alkoxyalkyl, alkylcarbonyl, alkylcarbonylalkyl, alkoxycarbonyl, alkenyl, cycloalkenyl, alkynyl, cyano, nitro, carboxyl, carboxyalkyl, alkylcarbonyloxy, alkylcarbonyloxyalkyl, alkoxycarbonylalkyl, aralkoxycarbonylalkyl, aralkylcarbonyloxyalkyl, mercaptocarbonyl, mercaptothiocarbonyl, mercaptoalkyl, alkoxycarbonyloxy, alkylthio, cycloalkylthio, alkylthiocarbonyl, alkylcarbonylthio, alkylthiocarbonyloxy, alkylthiocarbonylthio, alkylthiothiocarbonyl, alkylthiothiocarbonylthio, arylthio, arylthiocarbonyl, arylcarbonylthio, arylthiocarbonyloxy, arylthiocarbonylthio, arylthiothiocarbonyl, arylthiothiocarbonylthio, aralkylthio, aralkylthiocarbonyl, aralkylcarbonylthio, aralkylthiocarbonyloxy, aralkylthiocarbonylthio, alkylthiocarbonylalkyl, mercapto, alkylsulf inyl, alkylsulfonyl, aralkylsulfinyl, aralkylsulfonyl, arylsulfinyl, arylsulfonyl, and wherein each of R.sup.3 through R.sup.12 may be further independently selected from radicals of the formula ##STR36##wherein W is selected from divalent alkyl, divalent alkenyl and divalent alkynyl groups; wherein X is oxygen atom or sulfur atom; wherein each r is a number independently selected from zero and one; wherein each of R.sup.13 through R.sup.25 is independently selected from hydrido, alkyl, cycloalkyl, cycloalkylalkyl, aralkyl and aryl;and wherein any of the foregoing U, V, W and R.sup.1 through R.sup.25 groups having a substitutable position may be substituted by one or more groups independently selected from alkyl, halo, haloalkyl, halocycloalkyl, alkenyl, alkynyl, aralkyl, hydroxyalkyl, cyano, oxo, alkoxyalkyl, cycloalkyl, cycloalkylalkyl, aryl, aroylalkyl, cycloalkenyl, cyanoamino, alkylcarbonylalkyl, alkoxycarbonylalkyl, aralkoxycarbonylalkyl, carboxylalkyl, alkylthiocarbonylalkyl and alkylsulfonylalkyl;with the proviso that at least one of R.sup.3 through R.sup.12 must be selected from halo, haloalkyl and halocycloalkyl; and with the proviso that when any one of R.sup.3 through R.sup.7 are not hydrido, then R.sup.8 through R.sup.12 are each hydrido, and when any one of R.sup.8 through R.sup.12 are not hydrido, then R.sup.3 through R.sup.7 are each hydrido,or a tautomer thereof or a phartnaceutically-acceptable salt thereof.