Patent ID: 8858952
Filing Date: 2014-10-14
Classification: A61K,A61P,C07K,C12N

Abstract:
1. A method for activating T cells in a mammal, said method comprising administering a composition comprising a polypeptide to said mammal, wherein said polypeptide comprises an invariant chain amino acid sequence, an MHC class II epitope amino acid sequence, and a DC3 amino acid sequence, wherein said polypeptide is between 20 and 80 amino acids in length, wherein said invariant chain amino acid sequence comprises LRMK (SEQ ID NO:44), wherein said DC3 amino acid sequence comprises FYPSYHSTPQRP (SEQ ID NO:2), and wherein said MHC class II epitope amino acid sequence comprises KDISYLYRFNWNHCG (SEQ ID NO:1).