Patent ID: 6706164
Filing Date: 2004-03-16
Classification: C07K,G01N

Abstract:
In a microfluidics device of the type having a substrate having an upper surface, a channel network formed in the substrate, including a supply channel adapted to contain a sample, a drain channel, and an electrolyte channel adapted to contain an electrolyte buffer, wherein said supply and drain channels are each inclined with respect to the electrolyte channel, and which supply and drain channels intersect said electrolyte channel at a supply port and a drain port, respectively, wherein movement of sample material from the supply to the drain channel is effective to place a sample volume between the supply and drain ports in the electrolyte channel, an improvement comprising:at least one of said supply or drain channels having first and second channel segments with different channel widths, thereby to produce a desired flow or flow characteristic in the two-segment channel which is different from that in a channel having a single, uniform width.