Patent ID: 6403567
Filing Date: 2002-06-11
Classification: A61P,C07D,C07H

Abstract:
A compound having the formula: whereinR1 is â€”CH2OH; R2 and R4 are each hydrogen; R3 is selected from the group consisting of CO2R20, â€”CONR7R8 and aryl wherein the aryl substituent is optionally substituted with from 1 to 2 substituents independently selected from the group consisting of halo, C1-6 alkyl, CF3 and OR20; R7 is selected from the group consisting of hydrogen, C1-8 alkyl and aryl, wherein the alkyl and aryl substituents are optionally substituted with one substituent selected from the group consisting of halo, aryl, CF3, CN, and OR20 and wherein each optional aryl substituent is optionally substituted with at least one substituent selected from the group consisting of halo, alkyl, CF3 CN, and OR20; R8 is selected from the group consisting of hydrogen and C1-8 alkyl; and R20 is selected from the group consisting of hydrogen and C1-8 alkyl.