Patent ID: 6207826
Filing Date: 2001-03-27
Classification: B01J,C07D

Abstract:
A compound of the structure: ##STR2##whereinX is (--T--L).sub.yy is 0-3each T is, independently, a single bond, a methylene group or a group having the structure--{[CR.sup.1 R.sup.2 ].sub.m --B--[CR.sup.1 R.sup.2 ].sub.n --[C(D)].sub.p --E--}.sub.q --where:D is .dbd.O, .dbd.S, .dbd.NR.sup.3 ;B and E, independently, are a single bond, CH.dbd.CH, C.dbd.C, O, S, NR.sup.3, or C.sub.6 -C.sub.14 aryl;each R.sup.1, R.sup.2 and R.sup.3 is, independently, H, alkyl or haloalkyl having 1 to about 10 carbon atoms; alkenyl having 2 to about 10 carbon atoms; alkynyl having 2 to about 10 carbon atoms; or aryl having 6 to about 14 carbon atoms;m and n, independently, are zero to 5;p is zero or 1;q is 1 to about 10; andeach L is, independently, H, C.sub.2 -C.sub.10 alkyl or substituted alkyl, C.sub.2 -C.sub.10 alkenyl or substituted alkenyl, C.sub.2 -C.sub.10 alkynyl or substituted alkynyl, C.sub.4 -C.sub.7 carbocyclic alkyl, alkenyl or alkynyl or substituted carbocyclic, or C.sub.6 -C.sub.14 aryl or substituted aryl where the substituent groups are selected from hydroxyl, amino, alkoxy, alcohol, benzyl, phenyl, nitro, thiol, thioalkoxy, halogen, alkyl, aryl, alkenyl, or alkynyl groups, an ether having 2 to 10 carbon atoms and 1 to 4 oxygen or sulfur atoms, a nitrogen-containing heterocycle, a sulfur-containing heterocycle, an oxygen-containing heterocycle, a metal coordination group, a conjugate group, halogen, hydroxyl (OH), thiol (SH), keto (C.dbd.O), carboxyl (COOH), amide (CONR), amidine (C(.dbd.NH)NRR), guanidine (NHC(.dbd.NH)NRR), glutamyl, nitrate (ONO.sub.2), nitro (NO.sub.2), nitrile (CN), trifluoromethyl (CF.sub.3), trifluoromethoxy (OCF.sub.3), O-alkyl, S-alkyl, NH-alkyl, N-dialkyl, O-aralkyl, S-aralkyl, NH-aralkyl, amino (NH.sub.2), azido (N.sub.3), hydrazino (NHNH.sub.2), hydroxylamino (ONH.sub.2), sulfoxide (SO), sulfone (SO.sub.2), sulfide (S--), disulfide (S--S), silyl, a nucleosidic base or an amino acid side chain, wherein R is H or alkyl.