Patent ID: 6762303
Filing Date: 2004-07-13
Classification: C07D

Abstract:
A method for producing a pyridine compound represented by formula (II), comprising oxidizing a dihydropyridine compound represented by formula (I) (i) in the presence of at least one acid and at least one compound selected from the group consisting of nitrous acid and a nitrate, or (ii) in the presence of at least one base, and a hydrogen peroxide solution: wherein each of R1, R2, R3, R4, and R5 independently represents a hydrogen atom, a halogen atom, an alkyl group, an aryl group, an alkenyl group, a cyano group, a formyl group, a carboxyl group, an alkoxycarbonyl group, an aryloxycarbonyl group, a substituted or unsubstituted carbamoyl group, an alkyl carbonyl group, an arylcarbonyl group, a nitro group, a substituted or unsubstituted amino group, an acylamino group, a sulfonamido group, an imido group, an imino group, a hydroxyl group, an alkoxy group, an aryloxy group, an acyloxy group, an alkylsulfonyloxy group, an arylsulfonyloxy group, a sulfo group, a substituted or unsubstituted sulfamoyl group, an alkylthio group, an arylthio group, an alkylsulfonyl group, an arylsulfonyl group, a silyl group, a phosphoryl group, or a heterocyclic group; L represents an alkyl group, an alkoxy group, an aryl group, or an aryloxy group, each of which may have a substituent: wherein each of R1, R2, R3, R4, and R5 has the same meanings as those of formula (I).