Patent ID: 6759524
Filing Date: 2004-07-06
Classification: C07K,C12Q,G01N

Abstract:
An isolated nucleic acid sequence encoding a polypeptide selected from the following:(a) an isolated nucleic acid sequence encoding amino acids 1 to 501 of SEQ ID NO:1; or (b) an isolated nucleic acid sequence; wherein no more than 5 amino acids have been added to, deleted from, or substituted in the polypeptide encoded by the isolated nucleic acid of (a), and wherein said isolated nucleic acid sequence encodes a protein that binds with dehydrocoeleneterazine via covalent bonding in the presence of potassium ion or sodium ion, thereby emitting luminescence; or (c) an isolated nucleic acid sequence exhibiting at least 95% homology with the isolated nucleic acid sequence of part (a) or part (b), wherein said isolated nucleic acid sequence encodes a protein that binds with dehydrocoeleneterazine via covalent bonding in the presence of potassium ion or sodium ion, thereby emitting luminescence.