Patent ID: 6921633
Filing Date: 2005-07-26
Classification: A01N

Abstract:
1. A method of preserving a eukaryotic cell, tissue or organ comprising: a) contacting said cell, tissue or organ with a hypothermic storage solution, wherein said solution comprises: b) vitrifying said cell, tissue or organ, wherein said vitrification occurs both within said cell, tissue or organ and in said hypothermic storage solution comprising and comprised by said cell, tissue or organ; wherein said composition that inhibits apoptosis comprises an agent that interacts with a polypeptide that participates in an apoptotic pathway; and wherein said agent is a calpain inhibitor and is selected from the group consisting of leupeptin, calpain inhibitors I, II, III, IV and V, calpeptin, loxastatin, a peptide chloromethyl ketone and a peptide fluoromethyl ketone.