Patent ID: 8759362
Filing Date: 2014-06-24
Classification: A61K,A61P,C07D

Abstract:
1. A compound of formula I(d): or a pharmaceutically acceptable salt thereof, wherein X is —O—, —N(R R Ar Ar c is the integer 0, 1, or 2; Y E is ═O, ═S, ═CH(C R each R each Z each Z each Z each Z each J is independently selected from —OR provided that at least one R each R each R each R R each R each R each R each -halo is independently selected from —F, —Cl, —Br, and —I; each b is independently selected from the integers 1 and 2; n is the integer 1, 2, or 3; p is the integer 1 or 2; q is the integer 0, 1, 2, 3 or 4; r is the integer 0, 1, 2, 3, 4, 5, or 6; s is the integer 0, 1, 2, 3, 4, or 5; t is the integer 1, 2, or 3; u is the integer 1, 2, 3 or 4; v is the integer 1, 2, 3 or 4; and w is the integer 1, 2, 3, 4, or 5; provided that when the R 3 group shown in formula I(d) is —H, and Ar 2 is substituted phenyl, then Q is not CH 2 OH.