Patent ID: 8956617
Filing Date: 2015-02-17
Classification: A61K,Y10S

Abstract:
1. A method of administering a vaccine preparation comprising particles, the method comprising: pretreating the surface of a skin to which the vaccine preparation is to be administered by applying adhesive strips or instantaneous adhesive or glue to the surface of the skin in order to improve the opening of hair follicles by ablation of at most 50% of the corneal layer; and transcutaneously contacting the skin with the particles, wherein the particles have at least a cross section having a diameter of 0.1 nm to 0.2 μm after possible deformation; wherein the particles enter the hair follicles and, due to the diameter of the particles, diffuse through the epithelium of the hair follicles, resulting in an induction, stimulation or increase of a protective immune response.