Patent ID: 6592989
Filing Date: 2003-07-15
Classification: A61K,A61L,C01B,Y10S,Y10T

Abstract:
A hydroxy apatite composite comprising hydroxy apatite particles formed by reacting calcium hydroxide (Ca(OH)2) with phosphoric acid (H3PO4) under a condition of existing organic compound particles and the organic compound particles of which surfaces are integrally formed and composited with said hydroxy apatite particleswherein said hydroxy apatite is manufactured by a synthesizing method comprising the steps of: preparing a mixed material slurry by dispersing calcium hydroxide (Ca(OH)2) powder into a phosphoric acid (H3PO4) solution; conducting a mechanochemical milling treatment in which shearing force and compressive force based on a centrifugal force of a mechanical rotating body are imparted to the mixed material slurry, wherein a centrifugal effect imparted to the slurry by the centrifugal force of the mechanochemical milling treatment is 15 or more; and reacting the calcium hydroxide component with the phosphoric acid component under normal temperature and pressure thereby to prepare hydroxy apatite (HAp) powder having fine crystals.