Patent ID: 6342366
Filing Date: 2002-01-29
Classification: A23L,A61K,C12N,C12R,C12Y,Y10S

Abstract:
A method of enhancing the inherent antimicrobial activity of a biologically pure culture of a strain of Lactobacillus towards a target pathogenic microorganism, wherein the Lactobacillus strain has all of the identifying characteristics of a strain selected from the group consisting of Lactobacillus gasseri BCCM LMG P-18137, Lactobacillus gasseri BCCM LMG P-17632 and Lactobacillus crispatus BCCM LMG P-17631, and the target pathogenic microorganism is selected from the group consisting of Candida, &bgr;-hemolytic Streptococcus, Proteus, Escherichia and Trichomonas, which comprises adding to the liquid culture medium of a biologically pure culture of said Lactobacillus strain, a composition consisting of supernatant from the culture of said target pathogenic microorganism, wherein said supernatant is added at a ratio of 0.01 to 5.00% v/v prior to cultivation of the Lactobacillus strain in said liquid culture medium.