Patent ID: 6747064
Filing Date: 2004-06-08
Classification: A61K,A61P,C08G

Abstract:
A method for reducing pathologic hydrophobic interactions, comprising:administering to a patient at risk for cell damage a composition comprising a substantially pure polyoxypropylene/polyoxyethylene block copolymer composition, wherein said substantially pure polyoxypropylene/polyoxyethylene block copolymer composition is substantially free of unsaturated molecules, said substantially pure polyoxypropylene/polyoxyethylene block copolymer composition containing block copolyrmers with each of the block copolymers having the following general formula: HO(C2H4O)b(C3H6O)a(C2H4O)bH â€ƒwherein a is an integer such that the molecular weight represented by the polyoxypropylene portion of the respective block copolymer is between 900 Daltons and 15,000 Daltons, and b is an integer such that the molecular weight represented by the polyoxyethylene portion of the respective block copolymer constitutes between 5% and 95% of the respective block copolymer, and the polydispersity value is less than approximately 1.07, and whereby pathologic hydrophobic interactions are reduced by the restoration or maintenance of non-adhesive cell surfaces by the block copolymers.