Patent ID: 8691793
Filing Date: 2014-04-08
Classification: A61L,A61P,C08B,C08H,C08J,C08L,C12N

Abstract:
1. A modified-glycosaminoglycan comprising from 0.1% to 30% of its primary hydroxyl groups chemically substituted with -L-CO 2 H, or a salt or ester thereof, where L is a polyalkylene group having the formula —(CH 2 ) n —, and n is an integer in a range from 1-10, wherein when the glycosaminoglycan is hyaluronan, the primary hydroxyl groups are primary 0-6 hydroxyl groups of an N-acetyl-glucosamine residue, and when the glycosaminoglycan is other than hyaluronan, the primary hydroxyl groups are C-6 hydroxyl groups of a non-uronic acid sugar component of a repeating disaccharide subunit.