Patent ID: 7371576
Filing Date: 2008-05-13
Classification: A61K,A61P,C12N

Abstract:
1. A method of obtaining a culture of propagating pancreatic cells that exhibit a CD56 protein as a cell surface marker comprising: (a) isolating pancreatic cells from a pancreas, seeding the pancreatic cells in a culture vessel, and culturing the cells to induce expression of the CD56 protein; (b) harvesting the pancreatic cells from the culture vessel and contacting the pancreatic cells with a CD56 binding reagent; (c) selecting undifferentiated pancreatic cells that specifically bind to the CD56 binding reagent, wherein the undifferentiated pancreatic cells can be expanded in culture; and (d) separating the selected, undifferentiated pancreatic cells from pancreatic cells that do not bind the CD56 binding reagent to obtain the culture of propagating pancreatic cells that exhibit the CD56 protein as a cell surface marker.