Patent ID: 8236316
Filing Date: 2012-08-07
Classification: A61K,A61P,C07K

Abstract:
1. An isolated anti-Factor XI (FXI) antibody or biologically active fragment thereof which specifically binds human FXI described in SEQ ID NO: 1, wherein said antibody comprises: (a) an immunoglobulin heavy chain variable domain comprising three complementarity-determining regions (CDRs), wherein the three CDRs comprise the amino acid sequence of SEQ ID NO: 10, SEQ ID NO: 11 and SEQ ID NO: 12; and (b) an immunoglobulin light chain variable domain comprising three CDRs, wherein the three CDRs comprise the amino acid sequence of SEQ ID NO: 13, SEQ ID NO: 14 and SEQ ID NO: 15.