Patent ID: 6358886
Filing Date: 2002-03-19
Classification: A01N,C07D

Abstract:
A substituted aminotriazine having at least two asymmetrically substituted carbon atoms of the formula (I), whereinA represents a single bond, represents dimethylene (ethane-1,2-diyl, â€”CH2CH2â€”), oxaethanediyl (â€”CH2Oâ€”) or 2-oxapropane-1,3-diyl (â€”CH2OCH2â€”), R1 represents amino, represents formylamino or represents in each case optionally cyano-, fluorine-, chlorine-, methoxy- or ethoxy-substituted acetylamino, propionylamino, methoxycarbonylamino, ethoxycarbonylamino, or dimethylaminomethyleneamino, R2 represents hydrogen, R3 represents methyl, R4 represents methyl or ethyl, Y represents fluorine, and Z represents an optionally substituted phenyl, â€ƒwherein the substituents are selected from the group consisting of: hydroxyl, amino, cyano, nitro, carbamoyl, sulphamoyl, fluorine, chlorine, bromine, in each case optionally hydroxyl-, cyano-, fluorine- or chlorine-substituted methyl, ethyl, n- or i-propyl, n-, i-, s- or t-butyl, methoxy, ethoxy, n- or i-propoxy, dimethylamino, in each case optionally fluorine- and/or chlorine-substituted acetyl, methoxycarbonyl, ethoxycarbonyl, dimethylaminocarbonyl, methylthio, ethylthio, n- or i-propylthio, methylsulphinyl, ethylsulphinyl, methylsulphonyl, ethylsulphonyl or dimethylamino-sulphonyl, in each case optionally hydroxyl-, cyano-, nitro-, fluorine-, chlorine-, methyl-, ethyl-, n- or i-propyl-, n-, i-, s- or t-butyl-, trifluoro-methyl-, methoxy-, ethoxy-, n- or i-propoxy-, difluoromethoxy- or trifluoromethoxy-substituted phenyl or phenoxy, and in each case optionally fluorine- and/or chlorinesubstituted methylenedioxy or ethylenedioxy, â€ƒwith the proviso that the substituents at the two carbon atoms to which R2 and R3 or R4 are attached are configured as follows: (a) R configuration at the carbon atom to which R2 and R3 are attached and R configuration at the carbon atom to which R4 is attached (â€œR,R-diastereomersâ€ ), or (b) R configuration at the carbon atom to which R2 and R3 are attached and S configuration at the carbon atom to which R4 is attached (â€œR,S-diastereomersâ€ ).