Patent ID: 8673580
Filing Date: 2014-03-18
Classification: A61K,A61P,G01N

Abstract:
1. A method of mobilizing a bone marrow mesenchymal stem cell to peripheral blood from bone marrow, comprising the steps of administering to blood vessel or muscle of a living animal one or more substances selected from the group consisting of: (a) an HMGB1 protein; (b) a cell that secretes an HMGB1 protein; (c) a vector inserted with a DNA encoding an HMGB1 protein; (d) an HMGB2 protein; (e) a cell that secretes an HMGB2 protein; (f) a vector inserted with a DNA encoding HMGB2 protein; (g) an HMGB3 protein; (h) a cell that secretes an HMGB3 protein; and (i) a vector inserted with a DNA encoding an HMGB3 protein; and mobilizing a bone marrow mesenchymal stem cell to peripheral blood from bone marrow.