Patent ID: 6582662
Filing Date: 2003-06-24
Classification: B01F,B01J,B01L,G01N,Y10T

Abstract:
A centripetally-motivated microsystems platform comprising:a) a rotatable platform comprising a substrate having a surface comprising one or a multiplicity of microfluidics structures embedded in the surface of the platform, wherein each microfluidics structure comprises i) one or a plurality of reagent reservoirs containing a reagent solution ii) one or a plurality of sample reservoirs containing a sample solution, iii) a mixing microchannel, wherein each mixing microchannel is fluidly connected to a sample reservoir and one or a plurality of reagent reservoirs by a microchannel, and iv) a collection chamber fluidly connected to the mixing microchannel by a microchannel, wherein the mixing microchannel defines a longitudinal path in the surface of the platform, the mixing microchannel being configured to bend a plurality of times around a plurality of curves as it traverses the longitudinal path on the platform, the longitudinal path having a length sufficient to mix the sample solution and the reagent solutions to a homogenous mixture, and wherein fluid within the microchannels of the platform is moved through said microchannels by centripetal force arising from rotational motion of the platform for a time and a rotational velocity sufficient to move the fluid through the microchannels.