Patent ID: 8287840
Filing Date: 2012-10-16
Classification: A61K

Abstract:
1. A method for delivering a chemotherapeutic agent to a malignant solid tumor in a patient, comprising; delivering to the patient a first plurality of biodegradable microparticles through an artery to a first location at or near the malignant solid tumor, wherein the first plurality of biodegradable microparticles comprises a chemotherapeutic agent and wherein the first plurality of biodegradable microparticles has a mean diameter of about 10 to 300 μm; delivering a second plurality of biodegradable microparticles through the artery to a second location proximal to the location at which the first plurality of biodegradable microparticles was delivered, wherein the second plurality of biodegradable microparticles has a mean diameter of about 900 to about 1200 μm, and wherein: