Patent ID: 6767903
Filing Date: 2004-07-27
Classification: C07J

Abstract:
A testosterone compound of formula I in whichR6 is a hydrogen atom, a hydroxy group, a C1-C10 alkoxy group, a C1-C10 alkanoyloxy group or a halogen atom, R15 and R16 each are a hydrogen atom or together form a bond, R17a is a C1-C4 alkyl group, a C2-C4 alkinyl group, or a radical of formula CnFmHo, wherein n=1, 2, 3 or 4, m>1 and m+o=2n+1, R17b is a hydroxy group, a C1-C10 alkoxy group or a C1-C10 alkanoyloxy group, A is an unbranched C6-C13 alkylene group, B is an oxygen atom, a â€”S(O)p group, wherein p=0, 1 or 2, an iminocarbonyl group â€”C(O)N(Y)â€”, an imino group â€”N(Y)â€”, a carbonylimino group â€”N(Y)C(O)â€”, a sulfonylimino group â€”N(Y)S(O)2â€”, wherein Y is a hydrogen atom or a C1-C8 alkyl group, a sulfonyloxy group â€”OS(O)2â€”, a dimethylsilyloxy group â€”Oâ€”Si(CH3)2â€” or a carbonylsulfanyl group â€”SC(O)â€”, or B is a bond between A and C, or together with C forms a bond between A and D, C is a bond between B and D, or together with B forms a bond between A and D or an unbranched C1-C6 alkylene group, a phenylene group, a substituted phenylene group, a five-ring or six-ring heteroarylene group, a substituted five-ring or six-ring heteroarylene group, or a five-ring or six-ring heteroarylene group that is condensed with a phenyl ring, and D is a hydrogen atom, a C1-C4 alkyl group, a vinyl group, a C1-C4 alkoxy group, a C1-C4 alkoxycarbonyl group, a bis(C1-C4 alkoxycarbonyl)methyl group, an acetyl(C1-C4 alkoxycarbonyl)methyl group, a cyano group, a carboxy group, an azide group, a hydroxy group, a halogen atom or a radical of formula CnFmHo, wherein n=1, 2, 3 or 4, m>1 and m+o=2n+1.