Patent ID: 6589944
Filing Date: 2003-07-08
Classification: A61K,A61P,Y10S

Abstract:
A method of cleaving glycation endproducts or cross-linked proteins in an organism in need thereof, wherein said method comprises administering an effective amount of a compound or pharmaceutically acceptable salt thereof to said organism wherein said compound is selected from the group consisting of:(a) L-bis-[4-(4-chlorobenzamidophenoxyisobutyryl)cystine]; (b) 4-(3,5-dichlorophenylureido)phenoxyisobutyryl-1-amidocyclohexane-1-carboxylic acid; (c) methylene bis [4,4â€²-(2-chlorophenylureidophenoxyisobutyric acid)]; (d) 1,1-dimethylbiguanide; and (e) 5-aminosalicylic acid.