Patent ID: 6610858
Filing Date: 2003-08-26
Classification: A61P,C07D,C07F

Abstract:
A process for the formation of a compound of the formula (I): or a pharmaceutically acceptable salt form thereof; wherein:R1 is selected from H or NHC(&boxH;O)â€”Oâ€”R1b; R1b is selected from C1-8 alkyl; R2 is H; R3 and R4 are H; R5 is selected from the group consisting of: hydroxy, C1-C10 alkoxy; said process comprising: reacting a compound of formula (IV): wherein:R6 is selected from the group consisting of C1-C8 alkyl; with hydrogen under a suitable pressure in the presence of a hydrogenation catalyst to form a compound of formula (I) or a pharmaceutically acceptable salt form thereof.