Patent ID: 6114145
Filing Date: 2000-09-05
Classification: A61K,C07K

Abstract:
An isolated nucleic acid molecule encoding a Synferon polypeptide exhibiting an activity selected from the group consisting of:(i) anti-viral activity in vitro;(ii) bone marrow colony formation in vitro; and(iii) inhibition of GM-CSF induced proliferation of the erythroleukemic cell line TF-1;wherein said nucleic acid molecule comprises a polynucleotide sequence at least 90% identical to a sequence selected from the group consisting of:(a) a polynucleotide sequence encoding amino acid residues 1 to 161 of SEQ ID NO:2; and(b) a polynucleotide sequence encoding amino acid residues 2 to 161 of SEQ ID NO:2.