Patent ID: 7704503
Filing Date: 2010-04-27
Classification: A61K,A61P,C12N,G01N

Abstract:
1. A method of diagnosing cystic fibrosis in a subject, comprising the steps of: (a) measuring a test amount of an interleukin-17F (IL-17F) gene product in a sample from a subject suspected of having cystic fibrosis; (b) determining a normal range of the IL-17F gene product by measuring an amount of the IL-17F gene product in multiple samples from at least one healthy subject or at least one sample from multiple healthy subjects; and (c) comparing the test amount with the normal range of the IL-17F gene product, wherein the sample from the subject suspected of having cystic fibrosis and the multiple samples from at least one healthy subject or the at least one sample from multiple healthy subjects are selected from the group consisting of sputum, tissue from airway, and bronchoalveolar lavage; and whereby a test amount above the normal range provides a positive indication in the diagnosis of cystic fibrosis.