Patent ID: 7994190
Filing Date: 2011-08-09
Classification: A61P,C07D

Abstract:
1. A compound according to formula I, its enantiomer, diastereomers, and tautomers, or a pharmaceutically-acceptable salt, or hydrate, thereof, wherein the side chain group: is attached to the benzo ring at the 5- or 6-position; is heterocyclo or heteroaryl; E is —CR F is selected from —N— and —CR G is selected from N and —CR X is selected from O and (R M is selected from hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, aryl, heterocyclo, and heteroaryl; M Q is selected from where X is O, Z is selected from or when X═(R Z R R R R R R R or R R R p is 0, 1 or 2, provided that where the ring system and Q and M a -M are independently H, CH 3 or C 2 H 5 , then Z a —Z is other than where G 1 is a heteroaryl, acetyl, carbamoyl, or —C(═S)CH 3 or —C(═S)C 2 H 5 .