Patent ID: 6395557
Filing Date: 2002-05-28
Classification: G01N,Y10T

Abstract:
A method for determining the presence of an analyte in a solution, comprising the following steps:a) determining a system load loss of a conduit having a reduced cross section over all or part of it, as a function of fluid pressure and volumetric flow rate for a fluid circulating in said conduit, b) immobilizing said analyte on the inner surface of the reduced cross section of said conduit and determining a resulting load loss of the fluid circulating in the conduit, c) determining the variation in load loss of the fluid circulating in the conduit, due to the analyte which has been immobilized on the inner surface of the reduced cross section of said conduit during step b) as compared to the system load loss of step a), and d) correlating said variation in load loss to a standard to determine the presence of the analyte in the solution wherein, load loss is determined by measuring the pressure at constant flow rate or the flow rate at constant pressure between two points located either side of the reduced cross section of the conduit.