Patent ID: 7642267
Filing Date: 2010-01-05
Classification: A61P,C07D

Abstract:
1. A compound of the formula: or a pharmaceutically acceptable salt thereof, wherein: Z Z Z Z where Z R i) hydrogen, halogen, hydroxy, nitro, cyano, amino, haloalkyl, and haloalkoxy, ii) alkyl, alkoxy, cycloalkyl, alkenyl, alkynyl, (cycloalkyl)alkyl, —NH(R iii) a group of the formula: where G is a bond, alkyl, —O—, —C(═O)—, or —CH 2 C(═O)—, and R iv) a group of the formula where J is N, CH, or C-alkyl, and R R v) —OC(═O)R R R R Q represents —C(R R the group: represents a 5 to 7 membered heteroaryl or heterocycloalkyl ring containing up to 4 heteroatoms independently selected from nitrogen, sulfur, and oxygen, said 5 to 7 membered heteroaryl or heterocycloalkyl ring is substituted at each carbon atom by R, and substituted at each nitrogen atom available for substitution by R′, wherein X Y is nitrogen, oxygen, sulfur, carbon, —OH—, —OH W represents aryl or heteroaryl, wherein the aryl or heteroaryl group is optionally substituted with up to 4 groups independently selected from R