Patent ID: 8722896
Filing Date: 2014-05-13
Classification: A61P,C07D

Abstract:
1. A compound having a structure according to Formula 1 wherein R1 is an optionally substituted aryl, optionally substituted heteroaryl, or an optionally substituted aryl with a fused heterocyclic ring; X is CH2 and Y is lower alkyl; Q is NH or NR6, wherein R6 is lower alkyl; Z is CH2 or CHR7, wherein R7 is lower alkyl; or Q and Z are covalently coupled to each other to form a heterocyclic 4- to 6-membered ring in which Q is N and Z is CH, with the proviso that the heterocyclic ring is not a morpholine ring; R2 is CH2; R3 is H, lower alkyl, or alkaryl; A is N or C; W is H, or halogen, or W is null where A is N; and R4 and R5 are independently alkoxy, or are covalently coupled to each other to form an optionally substituted heterocyclic 6- or 7-membered ring with at least one oxygen atom.