Patent ID: 8992815
Filing Date: 2015-03-31
Classification: A61K,B01J,B23K,B82Y,Y10S

Abstract:
1. A method for producing a nanoparticle colloidal suspension of organic material dispersed in a poor solvent liquid, the method comprising steps of: irradiating a shaped bulk target of an organic compound material with an ultrashort pulsed laser beam having a pulse duration of 500 picoseconds or less and a pulse repetition rate of 10 kHz to 100 MHz, the target mounted during said irradiating over a flow cell holding the liquid so that at least a portion of the target is submerged below the liquid surface, the liquid being substantially transparent at a wavelength of the pulsed laser beam, the irradiation generating a nanoparticle suspension of the organic compound material in the liquid by ablation through the liquid and flow cell, the liquid and nanoparticle suspension being free of stabilizing agents and surface active agents, and the nanoparticle suspension being stable at 25° C. for 7 days; and producing a movement of the liquid into and out of the flow cell and across a submerged target surface during said irradiating.