Patent ID: 6602881
Filing Date: 2003-08-05
Classification: A61K,A61P

Abstract:
A method for treating a neurodegenerative condition, in a human or animal, wherein said condition is selected from the group consisting of Down's syndrome, post ischemic brain injury, meningitis, septic shock, HIV encephalopathy, Parkinson's disease, alzheimer's disease, amyotrophic lateral sclerosis, and multiple sclerosis, said method comprising administering an effective amount of a compound, or a salt thereof, wherein said compound has a structure selected from the group consisting of: wherein X1, X2, X3, X4, X5, and X6 are a hydrogen, halogen, hydroxy, lower alkoxy, lower acyloxy, or lower mono or dialkyl amino group; R1 is hydrogen, lower alkyl, or lower acyl group; R2 is hydrogen, hydroxy, lower alkoxy, or lower acyloxy group; â€ƒwherein X1, X2, X3, X4, X5, and X6 are the same or different and are a hydrogen, halogen, hydroxyl, lower alkoxy, lower acyloxy, thiol, lower alkylthiol, nitro, amino, lower alkylsulfonyl, aminosulfonyl, hydroxy sulfonyl (â€”SO3H), lower acylamino, lower alkyl, or lower monoalkyl- or dialkyl-amino group; R1 and R2 are the same or different and are a hydrogen, lower alkyl, or lower acyl group; and Y is a hydrogen, hydroxyl, lower alkoxy, or lower acyloxy group; and â€ƒwherein R is a hydrogen, halogen, hydroxy, or lower acyloxy group; and X is a double bonded oxygen, or is the same or different and is any two of a hydrogen, hydroxy, lower alkyl, lower alkoxy, or lower acyloxy group wherein said lower alkyl, alkoxy, or acyloxy groups have from 1 to about 5 carbon atoms.