Patent ID: 9200044
Filing Date: 2015-12-01
Classification: A61K,A61P,C07K

Abstract:
1. A polynucleotide comprising a nucleic acid sequence encoding a modified mycobacterium Rv3616c protein, said modified mycobacterium Rv3616c protein comprising a first polypeptide and a second polypeptide, the first polypeptide being located towards the N-terminus relative to the second polypeptide, and wherein: (i) the first polypeptide has at least 98% identity to residues 1-134 of SEQ ID No: 1; and (ii) the second polypeptide has at least 98% identity to residues 155-392 of SEQ ID No: 1; wherein the first and second polypeptides are (A) directly linked or (B) indirectly linked via a third polypeptide having at least 80% identity to a sequence corresponding to residues 135-154 in SEQ ID No:1 in which a contiguous portion of at least 3 amino acids has been deleted.