Patent ID: 8674291
Filing Date: 2014-03-18
Classification: C12Q,G01N,H01J

Abstract:
1. A method for determining in a sample, by mass spectrometry, the amounts of at least three analytes selected from the group consisting of pregnenolone, 17-OH pregnenolone, progesterone, 17-OH progesterone, dehydroepiandrosterone (DHEA), androstenedione, testosterone, 11-deoxycortisol, deoxycorticosterone, and cortisol, the method comprising: subjecting the sample to an ionization source under conditions suitable to produce one or more ions detectable by mass spectrometry from each of the analytes, wherein the analytes are not derivatized prior to ionization; determining, by tandem mass spectrometry, the amounts of the one or more ions from each of the analytes; and using the determined amounts of the one or more ions to determine the amount of each of the analytes in the sample.