Patent ID: 7253319
Filing Date: 2007-08-07
Classification: A61P,C07C,C07D

Abstract:
1. A compound of the formula wherein R is selected from the groups consisting of the radicals defined by formulas (a) through (d) where the dashed line in a ring represents a bond, or absence of a bond with the proviso that one and only one dashed line in the ring represents a bond; a * denotes a ring carbon to which the chalcone oxime group is attached; X is (R Y is a phenyl or naphthyl group, or heteroaryl selected from a group consisting of pyridyl, thienyl, furyl, pyridazinyl, pyrimidinyl, pyrazinyl, thiazolyl, oxazolyl, imidazolyl and pyrrazolyl, said phenyl and heteroaryl groups being optionally substituted with one or two R m is an integer having the values 0 to 5; n is an integer having the values 0 to 3; p is an integer having the values 0 to 2; r is an integer having the values 0 to 5; R R R R R A is (CH B is COOH or a pharmaceutically acceptable salt thereof, COOR