Patent ID: 6013242
Filing Date: 2000-01-11
Classification: A61K,C07D

Abstract:
A 3-aryltropane compound having the formula: ##STR28## R.sub.1 is selected from the group consisting of hydrogen and C.sub.1 to C.sub.8 alkyl;R.sub.2 is selected from the group consisting of hydrogen, iodo, radioisotopic halo, C.sub.1 to C.sub.8 alkyl and tri lower alkyl (C.sub.1 to C.sub. 8) tin; andR.sub.1 and R.sub.2 may be fused by a --N(Me)CH.dbd.CH-- to form a pyrrole ring;R.sub.3 is selected from the group consisting of hydrogen, iodo, radioisotopic halo, or C.sub.1 to C.sub.8 alkyl;R.sub.4 is selected from the group consisting of hydrogen and C.sub.1 to C.sub.8 alkyl; and,R.sub.5 is selected from the group consisting of hydrogen or C.sub.1 to C.sub.8 alkyl, and salts, solvates and hydrates thereof;and further providing that one of R.sub.2 and R.sub.3 is a radioisotopic halo.