Patent ID: 8361470
Filing Date: 2013-01-29
Classification: A61K,A61P,C07K,Y10S

Abstract:
1. A method of treating a subject having an IL-21-mediated disease, the method comprising administering to said subject an anti-IL-21 antibody, or antigen binding portion thereof, comprising a heavy chain variable region comprising amino acid residues 20 to 139 of SEQ ID NO: 61 or a light chain variable region comprising amino acid residues 23 to 129 of SEQ ID NO: 69, or a heavy chain variable region comprising amino acid residues 20 to 145 of SEQ ID NO: 29 or a light chain variable region comprising amino acid residues 21 to 126 of SEQ ID NO: 37, wherein IL-21 activity is inhibited.