Patent ID: 7927826
Filing Date: 2011-04-19
Classification: C12Q,G01N

Abstract:
1. A method for distinguishing follicular thyroid adenoma (FTA) from follicular thyroid carcinoma (FTC) comprising the steps of: determining amount of an expression product of at least one gene selected from the group consisting of DDIT3, ARG2, ITM1, C1orf24, TARSH, and ACO1 in a test follicular thyroid specimen; comparing the amount in the test specimen to the amount in a normal control thyroid specimen, wherein the expression product is selected from the group consisting of protein and RNA; identifying the test follicular thyroid specimen as FTA if the amount of expression product of TARSH is equal to or greater in the test follicular thyroid specimen than in the normal control thyroid specimen, or identifying the test follicular thyroid specimen as FTC if the amount of expression product of DDIT3, ARG2, ITM1, C1orf24, or ACO1 is greater in the test follicular thyroid specimen than in the normal control thyroid specimen.