Patent ID: 6713065
Filing Date: 2004-03-30
Classification: A01K,A61K,A61P,C12N,G01N

Abstract:
A method of stimulating a population of undifferentiated mammalian mesodermally derived cells to undergo hematopoiesis, comprising contacting the cells with an amount of a hedgehog compound effective to stimulate the cells to undergo hematopoiesis, wherein the hedgehog compound comprises a polypeptide sequence at least 80% identical to a sequence selected from SEQ ID NO: 34, SEQ ID NO: 35, SEQ ID NO: 36, SEQ ID NO: 37, SEQ ID NO: 38, SEQ ID NO: 39, SEQ ID NO: 40, or a fragment of said polypeptide sequence which polypeptide sequence or fragment of said polypeptide sequence binds to patched and induces cells to undergo hematopoiesis.