Patent ID: 6787125
Filing Date: 2004-09-07
Classification: A01K,C07K,C12N,C12Q,G01N

Abstract:
A method of identifying chemical substances which have potential pharmacological activity using nematode worms, which method comprises the steps of:(a) dispensing substantially equal numbers of nematode worms into each of the wells of a multi-well assay plate; (b) contacting the nematode worms with a chemical substance; (c) detecting a signal indicating phenotypic, physiological, behavioral, or biochemical changes in the nematode worms using non-visual detection means; wherein step (a) is performed in a multi-well plate with liquid assay medium containing a water soluble polymer at a concentration sufficient to increase the viscosity of the medium; wherein the water soluble polymer is medium viscosity carboxymethyl cellulose.