Patent ID: 6103112
Filing Date: 2000-08-15
Classification: B01D,B01J,C12N,C12Q,G01N

Abstract:
A liquid chromatography apparatus for polynucleotide separations by MIPC and DMIPC processes comprising:heater means having a temperature control system;a matched ion polynucleotide chromatography separation column having an inlet end;a length of capillary liquid heating tubing having an inlet end and an outlet end, the outlet end of the capillary tubing being connected with the inlet end of the separation column, and the inlet end of the capillary tubing comprising means for receiving process liquid, the tubing having a fully extended length of from 6 to 400 cm the length and diameter of tubing being sufficient to enable liquid passing therethrough to reach an equilibrium temperature;the separation column and the coil of capillary tubing being positioned in the heater means; andthe temperature control system being calibrated to the temperature of liquid flowing into the separation column.