Patent ID: 8889154
Filing Date: 2014-11-18
Classification: A61K

Abstract:
1. A packaged composition containing an imiquimod formulation and a durable laminated packaging material for storing the imiquimod formulation therein, the packaged composition enabling storage of the imiquimod formulation for an extended period of time within the durable laminated packaging material, said packaged composition comprising: (a) the durable laminated packaging material forming a pouch comprising: (i) a contact layer comprising an acrylonitrile-methyl acrylate copolymer; (ii) an outer layer; (iii) a moisture barrier layer disposed between the contact layer and the outer layer; and (b) the imiquimod formulation comprising 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine and a fatty acid; wherein, the imiquimod formulation is enclosed within the durable laminated packaging material and is in direct contact with the contact layer; and wherein the imiquimod formulation, when enclosed within the pouch and in direct contact with the contact layer, is stable for at least about 6 weeks at about 60° C. and at ambient relative humidity (RH), and wherein the durable laminated packaging material, when stored in direct contact with the imiquimod formulation at about 40° C. and at about 76% RH, remains durable over a period of at least about 1 month.