Patent ID: 7595058
Filing Date: 2009-09-29
Classification: A61K,A61P,C07K,C12N,Y02A,Y10S

Abstract:
1. A method for inhibiting Chlamydia pneumoniae proliferation in a subject, the method comprising the step of administering to the subject a vaccine composition comprising a substantially purified protein and an adjuvant, wherein the protein comprises: (a) the amino acid sequence set forth in SEQ ID NO:2, or (b) the amino acid sequence set forth in SEQ ID NO:4, or (c) an amino acid sequence comprising an immunogenic fragment of SEQ ID NO:2, the fragment consisting of at least amino acids 1-452 of SEQ ID NO:2, or (d) an amino acid sequence comprising an immunogenic fragment of SEQ ID NO:2, the fragment consisting of at least amino acids 69-651 of SEQ ID NO:2; wherein the adjuvant facilitates delivery and/or enhances an immune response to the part of the protein having the amino acid sequence defined in (a) to (d).