Patent ID: 8497283
Filing Date: 2013-07-30
Classification: A61P,C07D

Abstract:
1. A method for inhibiting autotaxin, comprising administering to a subject in need thereof an effective amount of a compound of formula (I) wherein: W Y Y Z L is independently selected from the group consisting of: B is independently selected from the group consisting of “cycloalkyl, heterocyclyl, aryl, heteroaryl”, wherein “cycloalkyl, heterocyclyl, aryl, heteroaryl” can be independently substituted with one or more identical or different substituents selected from the group consisting of: “(i) “hydrogen, alkyl, (C R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17 are independently from each other selected from the group consisting of: “V”; V is independently selected from the group consisting of: “(i) “hydrogen, alkyl, (C n is independently 0, 1, 2, 3 or 4; and the physiologically acceptable salts, and stereoisomers thereof, including mixtures thereof in all ratios.