Patent ID: 7420054
Filing Date: 2008-09-02
Classification: C07D,C12Q

Abstract:
1. A chromogenic enzymatic substrate corresponding to formula (I) below: in which R or an optionally substituted coumarin ring of formula: or R R or R it being understood that: (i) at least one among R (ii) when R R it being understood that R 6 represents a halogen atom when R 1 /R 2 and R 3 /R 4 each form, with the phenyl ring to which they are attached, a naphthalene ring, R or R R it being understood that, when R 9 is different from a hydrogen atom, then R 5 is a hydrogen atom, R′ represents a hydrogen atom or a C R″ represents a hydrogen atom or a C or R′ and R″, together with the nitrogen atom to which they are attached, form a heterocyclic ring containing one or more hetero atoms, A represents at least one amino acid, and X represents a blocking agent or is not present.