Patent ID: 7265130
Filing Date: 2007-09-04
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A pharmaceutical composition comprising a therapeutically effective amount of a compound of the formula (I): wherein R 1 is optionally substituted lower alkyl or optionally substituted cycloalkyl, R n is 1 or 2, R is optionally substituted cycloalkylene or optionally substituted bicycloalkylene, provided that is not and p and q are each independently 0 or 1, R Z is optionally substituted phenyl, optionally substituted phenyl fused with a nonaromatic ring selected from cyclopentane, cyclopentene or cyclohexane; optionally substituted naphthyl, optionally substituted anthryl, optionally substituted biphenyl or a fused heterocyclyl consisting of two rings, selected from the group consisting of indolyl, isoindolyl, indazolyl, indolizinyl, indolinyl, isoindolinyl, quinolyl, isoquinolyl, cinnolinyl, phthalazinyl, quinazolinyl, naphthyridinyl, quinoxalinyl, purinyl, pteridinyl, benzopyranyl, benzimidazolyl, benzisoxazolyl, benzoxazolyl, benzoxadiazolyl, benzisothiazolyl, benzothiazolyl, benzothiadiazolyl, benzofuryl, isobenzofuryl, benzothienyl, benzotriazolyl, imidazopyridyl, triazolopyridyl, imidazothiazolyl, pyrazinopyridazinyl, tetrahydroquinolyl and tetrahydrobenzothienyl; or a pharmaceutically acceptable salt thereof.