Patent ID: 6552088
Filing Date: 2003-04-22
Classification: A61P,C07C,C07D

Abstract:
A compound of formula: wherein R is hydrogen, lower alkyl, lower alkoxy, halogen, amino, â€”N(R6)2 or trifluoromethyl; R1 is hydrogen, lower alkoxy or halogen; R and R1 may be together â€”CH&boxH;CHâ€”CH&boxH;CHâ€”; R2 is halogen, lower alkyl or trifluoromethyl; R3 is hydrogen or lower alkyl; R4 is hydrogen or a cyclic tertiary amine, optionally substituted by lower alkyl; R5 is hydrogen, nitro, amino or â€”N(R6)2; R6 is hydrogen or lower alkyl; X is â€”(CH2)nOâ€”; and n is 1 or 2; or a pharmaceutically acceptable acid addition salt thereof.