Patent ID: 8138173
Filing Date: 2012-03-20
Classification: A61P,C07D

Abstract:
1. A compound of the Formula III: wherein: R R is selected from the group consisting of halogen, hydroxy, alkyl, alkenyl, haloalkyl, alkoxy, alkylthio, and —N(R n is an integer from 0 to 4; R R R m is 0 or 1, with the proviso that when m is 1 then n is 0 or 1; X is selected from the group consisting of alkylene, alkenylene, alkynylene, arylene, heteroarylene, and heterocyclylene wherein the alkylene, alkenylene, and alkynylene groups can be optionally interrupted or terminated by arylene, heteroarylene or heterocyclylene and optionally interrupted by one or more —O— groups; Y is-selected-from the group consisting of: Z is a bond or —O—; R R R R R R R A is selected from the group consisting of —O—, —C(O)—, —S(O) A′ is selected from the group consisting of —O—, —S(O) Q is selected from the group consisting of a bond, —C(R V is selected from the group consisting of —C(R W is selected from the group consisting of a bond, —C(O)—, and —S(O) a and b are independently integers from 1 to 6 with the proviso that a+b is ≦7; with the proviso that R 1 is other than hydrogen, methyl, or phenyl; and with the further proviso that the compound is other than N-[1,1-dimethyl-2-(2-methyl-2H-pyrazolo[3,4-c]quinolin-1-yl)ethyl]benzamide; or a pharmaceutically acceptable salt thereof.