Patent ID: 7871827
Filing Date: 2011-01-18
Classification: B01F,B01J,B01L,C12N,Y10T

Abstract:
1. A method of controlling fluid flow through a sample processing device, the method comprising: providing a sample processing device comprising a substrate that comprises first and second major sides and a first cover attached to the first major side of the substrate, the sample processing device further comprising a process array formed therein, the process array comprising a first chamber defining a first chamber volume, a second chamber, a channel extending between the first chamber and the second chamber, and a valve lip separating the first chamber from the channel, wherein the first chamber comprises a bottom located on an opposite side of the first chamber from the first cover, wherein the first chamber volume comprises a first portion and a second portion, wherein the first portion of the first chamber volume is located between the valve lip and the bottom of the first chamber, and wherein the second portion of the first chamber volume is defined on one side by the bottom of the first chamber and on an opposite side by the first cover, wherein the valve lip is not located between the second portion of the first chamber volume and the first cover; forming an opening in the valve lip, wherein the first chamber is in fluid communication with the channel after forming the opening; and rotating the sample processing device about an axis of rotation after forming the opening to move sample material from the first chamber into the channel through the opening.