Patent ID: 8815838
Filing Date: 2014-08-26
Classification: A61K,A61P,Y02A

Abstract:
1. A method for treating a pulmonary infection, comprising administering to a human having said pulmonary infection an aerosol of a solution comprising levofloxacin or ofloxacin and a divalent or trivalent cation to achieve a maximum lung sputum concentration (C max ) of at least 1200 mg/L and a lung sputum area under the curve (AUC) of at least 1500 h·mg/L, wherein the solution comprises a divalent or trivalent cation concentration from about 50 mM to about 400 mM, and a levofloxacin or ofloxacin concentration from between about 50 mg/ml to about 200 mg/ml.