Patent ID: 7867727
Filing Date: 2011-01-11
Classification: A61P,C12Q,G01N,Y10T

Abstract:
1. A screening method for determining a human subject's propensity to develop an abdominal aortic aneurysm and/or age-related macular degeneration (AMD) comprising: analyzing a biological sample from the subject to detect the presence or absence of a deletion of at least 1000 bp in the region of chromosome 1 between the 3′ end of exon 22 of the complement factor H (CFI-1) gene and the 5′ end of exon 1 of complement Factor H-related 4 (CFHR4) gene wherein the presence of a deletion indicates the subject is at increased risk of developing an abdominal aortic aneurysm and is at decreased risk of developing AMD.