Patent ID: 8999385
Filing Date: 2015-04-07
Classification: A61J,A61K,A61P

Abstract:
1. A method for producing a pharmaceutical composition that when placed in the mouth immediately disintegrates releasing active ingredient (a) comprising: vigorously mixing (a) an anionic active pharmaceutical ingredient with (b) a copolymer consisting of free-radical polymerized C (c) 5 to 50% by weight, based on (b), of a C solidifying the mixture, grinding the mixture to an active ingredient-containing powder with an average particle size of 200 μm or less, and incorporating the powder into a water-soluble matrix of at least one pharmaceutically acceptable excipient, with the proviso that not more than 3% by weight, based on the copolymer (b), of emulsifiers having an HLB of at least 14 may be present.