Patent ID: 6048980
Filing Date: 2000-04-11
Classification: C07D

Abstract:
A process for the preparation of compounds of formula (VII) starting from compound (V), obtainable according to claims 5-6, by alkylation, according to known methods, with an excess of an R--CH(X)--COY alkylating agent of formula (VI), optionally followed by hydrolysis of the ester groups present, represented by following Scheme: ##STR59## wherein: R is a hydrogen atom, a straight, branched or cyclic C.sub.1 -C.sub.6 alkyl group, unsubstituted or substituted with 1 to 10 oxygen atoms, or a C.sub.1 -C.sub.20 alkyl group, optionally interrupted by a phenylene, phenyloxy or phenylenedioxy, in its turn substituted with a straight or branched C.sub.1 -C.sub.6 alkyl group, unsubstituted or substituted with 1 to 7 hydroxy groups or with 1 to 3 C.sub.1 -C.sub.7 groups;the aromatic group can be unsubstituted or substituted with alkoxy groups or halogens, carboxy, carbamoyl, alkoxycarbonyl, sulfamoyl, hydroxyalkyl, amino, acylamino, acyl, hydroxyacyl groups;X is a halogen or a sulfonic acid reactive residue;Y is a --OH or --OR.sub.1 group, wherein R.sub.1 is a straight or branched C.sub.1 -C.sub.4 alkyl group; andwhen Y is the same as --OR.sub.1, the ester groups are also hydrolysed to obtain the compounds (VII).