Patent ID: 7935530
Filing Date: 2011-05-03
Classification: C08L,C12N

Abstract:
1. A polyamide-tail conjugate comprising a tail linked to a polyamide, wherein said polyamide is capable of binding DNA with an affinity of less than 100 nM, and wherein said tail comprises a linker and an end-group, and (a) wherein said linker is a C (b) wherein said end-group is selected from the group consisting of isophthalic acid; phthalic acid; terephthalic acid; morpholine; N,N-dimethylbenzamide; N,N-bis(trifluoromethyl)benzamide; fluorobenzene; (trifluoromethyl)benzene; nitrobenzene; phenyl acetate; phenyl 2,2,2-trifluoroacetate; phenyl dihydrogen phosphate; 2H-pyran; 2H-thiopyran; benzoic acid; isonicotinic acid; and nicotinic acid; where one, two or three ring members in any of these end-group candidates may be independently substituted with C, N, S or O; and