Patent ID: 6680057
Filing Date: 2004-01-20
Classification: A61K,C07K,Y10S

Abstract:
A method for treating autoimmune disease, comprising administering to an individual afflicted with an autoimmune disease a composition comprising an effective amount of an Interleukin-17 receptor (IL-17R) protein selected from the group consisting of:(a) a protein comprising amino acids 1 through 322 of SEQ ID NO:2; (b) a protein comprising amino acids 1 through 320 of SEQ ID NO:10; (c) analogs of (a) that are at least 80% identical to amino acids 1 through 322 of SEQ ID NO:2 and analogs of (b) that are at least 80% identical to amino acids 1 through 320 of SEQ ID NO:10, wherein the analog proteins are soluble and have the capacity to bind IL-17; and (d) fragments of the proteins of (a), (b), or (c), wherein said fragments comprise the extracellular domain of the proteins of SEQ ID NO:2 or SEQ ID NO:10 and bind IL-17; and a suitable carrier.