Patent ID: 7709501
Filing Date: 2010-05-04
Classification: A61P,C07D

Abstract:
1. A compound having the structure: or any pharmaceutically-acceptable salt or hydrate thereof, wherein: J is O or S; X is —C(R n is independently, at each instance, 0, 1 or 2; R R R (A) C (B) a saturated, partially saturated or unsaturated 5-, 6- or 7-membered monocyclic or 6-, 7-, 8-, 9-, 10- or 11-membered bicyclic ring containing 0, 1, 2, 3 or 4 atoms selected from N, O and S, wherein the available carbon atoms of the ring are substituted by 0, 1 or 2 oxo or thioxo groups, wherein the ring is substituted by 0, 1, 2 or 3 substituents independently selected from R (C) —N(R (D) —OC (E) H, C R R R R R R R R R R R