Patent ID: 9056119
Filing Date: 2015-06-16
Classification: A61K,A61P,A61Q,C07J

Abstract:
1. A method of promoting VEGF production, comprising applying an external preparation for skin to a subject in need of promoting VEGF production in said subject's skin keratinocytes, the external preparation for skin comprising a VEGF production promoting amount of a cycloartane-type glycoside represented by the following general formula (1): where R represents a xylose residue or an arabinose residue, and the ring D moiety represents any one of the following moieties a to f: where R 1 represents a hydrogen atom or a methyl group, R 2 represents a hydrogen atom or an acetyl group, R 3 represents a hydrogen atom or a hydroxyl group, R 4 represents a hydrogen atom or a hydroxyl group, and Ac represents an acetyl group, and promoting the VEGF production as a result of the applying.