Patent ID: 6916789
Filing Date: 2005-07-12
Classification: A61K,C07K

Abstract:
1. A purified synthetic polypeptide ligand comprising a 12-mer L-peptide or a homologue thereof, said 12-mer L-peptide consisting of SEQ ID NO:1 wherein said homologue is at least {fraction (10/12)} homologous to said 12-mer peptide and wherein said 12-mer L-peptide or homologue thereof, when integrated as an N-terminal PIII fusion peptide of an M13 phage confers an ability to bind the phage to either Caco-2 cell, IEC-6 cell, rat, mouse, pig or dog homogenate membrane fractions, said ability to bind being at least as great as that conferred by a similarly integrated 12-mer peptide of SEQ ID NO:67.