Patent ID: 8673652
Filing Date: 2014-03-18
Classification: A61K,C07K,G01N

Abstract:
1. A method of detecting or determining zolpidem and/or 4-[3-(2-N,N-dimethylamino-2-oxoethyl)-6-methylimidazo[1,2-a]pyridin-2-yl]benzoic acid in a solution or an in vitro sample taken from a patient, comprising: contacting the solution or sample with an antibody raised against an immunogen of the structure I: wherein, measuring a detectable signal generated from the conjugate upon binding of the antibody to zolpidem and/or 4-[3-(2-N,N-dimethylamino-2-oxoethyl)-6-methylimidazo[1,2-a]pyridin-2-yl]benzoic acid and deducing the presence of or amount of zolpidem and/or 4-[3-(2-N,N-dimethylamino-2-oxoethyl)-6-methylimidazo[1,2-a]pyridin-2-yl]benzoic acid in the sample, wherein the antibody has more than 5% cross-reactivity with 4-[3-(2-N,N-dimethylamino-2-oxoethyl)-6-methylimidazo[1,2-a]pyridin-2-yl]benzoic acid based on 100% specificity to zolpidem.