Patent ID: 7319117
Filing Date: 2008-01-15
Classification: A61K,A61Q,B01F,C10M,C10N,C11D

Abstract:
1. A process for preparing a multiple emulsion comprising an inverse emulsion consisting of an inner aqueous phase dispersed in an inner organic phase, the inverse emulsion being dispersed in an outer aqueous phase; the inner aqueous phase optionally comprising at least one hydrophilic active material; the inner organic phase optionally comprising at least one hydrophobic active material; the inverse emulsion comprising at least one inner surfactant and/or at least one inner amphiphilic polymer; the outer aqueous phase optionally comprising at least one hydrophilic active material and at least one outer surfactant or at least one outer amphiphilic polymer; said process comprising the following steps: a) preparing the inverse emulsion; b) preparing the outer aqueous phase; c) adding the outer aqueous phase into the inverse emulsion, without stirring; d) stirring the mixture to obtain a concentrated multiple emulsion; and e) optionally, diluting the concentrated multiple emulsion obtained in step d) by adding, with stirring, an aqueous dilution phase comprising at least one outer surfactant or at least one outer amphiphilic polymer, in order to obtain a dilute multiple emulsion.