Patent ID: 7510848
Filing Date: 2009-03-31
Classification: B01J

Abstract:
1. A method of detecting and separating a prion protein from a whole blood sample comprising: contacting a whole blood sample with a polymeric prion protein binding material under conditions allowing binding of the prion protein and the polymeric prion protein binding material, and detecting and separating, from the whole blood sample, prion protein that is bound to the binding material, wherein the polymeric prion protein binding material comprises a matrix bound to a functional group, which matrix comprises polymethacrylate, methacrylate, or a combination thereof, and which functional group is an amine group, a sulfite group, a sulfonyl group, a tresyl group, a butyl group, or a phenyl group, and wherein the binding material is capable of binding specifically and selectively to the prion protein from whole blood.