Patent ID: 8318788
Filing Date: 2012-11-27
Classification: A61K,A61P

Abstract:
1. A method for affecting weight loss in a patient, comprising: identifying a patient in need of weight loss; administering to the patient a layered pharmaceutical formulation comprising a first pharmaceutical layer comprising naltrexone, a second pharmaceutical layer comprising bupropion, and an intermediate layer disposed between the first and the second pharmaceutical layers, wherein the intermediate layer is configured to rapidly dissolve in vivo, and thereby leave the first and the second pharmaceutical layers substantially intact but physically separated, and wherein the dissolution profile of naltrexone in the pharmaceutical formulation is substantially the same as a single compressed tablet of naltrexone having the same size and shape as the first pharmaceutical layer, and wherein the dissolution profile of bupropion in the layered pharmaceutical formulation is substantially the same as a single compressed tablet of the same pharmaceutical composition, size and shape as the second pharmaceutical layer.