Patent ID: 7091372
Filing Date: 2006-08-15
Classification: A61P,C07C

Abstract:
1. A process for the preparation of any one of the compounds of formulae (Ia), (Ib) and (Ic) or a mixture thereof: wherein R R may optionally and independently be replaced by a nitrogen, oxygen or sulfur, and wherein said monocyclic and bicyclic rings may optionally be substituted with one to two substituents for the monocyclic rings and from one to three substituents for the bicyclic rings, that are selected, independently, from the group consisting of (C 0 –C 6 )alkyl- and (C 1 –C 6 )alkoxy-(C 0 –C 6 )alkyl-, wherein the total number of carbon atoms does not exceed six and wherein any of the alkyl moieties may optionally be substituted with from one to seven fluorine atoms; oxo, fluoro, chloro, ((C 1 –C 6 )alkyl) 2 amino-, —CO 2 R 7 , —CONR 8 R 9 , and —SO 2 NR 10 R 11 ; each R or two R R R each R each L is independently H, (C and each R comprising the step of reacting a compound of formula (III) wherein R