Patent ID: 6524327
Filing Date: 2003-02-25
Classification: C08G,C09J

Abstract:
A tissue crosslinked hydrophilic, biocompatible hydrated bond prepared by reacting together tissue pre-treated with hydrogen peroxide, body derived fluids and a prepolymer in a prepolymer-to-water ratio of 3:1 to 20:1, said prepolymer prepared by:(a) selecting diols or polyols, substantially all of which are oxyethylene-based diols or polyols having an average molecular weight of 3,000 to about 30,000, and (b) reacting said diols or polyols with an aliphatic or aromatic polyisocyanate at an isocyanate-to-hydroxyl ratio of about 1.5 to 2.5 so that all of the hydroyl groups of said diols or polyols are capped with polyisocyanate and the resulting prepolymer has an isocyanate concentration of no more than 0.8 milliequivalents per gram.