Patent ID: 8137690
Filing Date: 2012-03-20
Classification: A61K,A61P

Abstract:
1. A system for use in balancing neurotransmitter levels in a subject through a taste titration, the system comprising: a serotonergic formulation comprising a serotonergic agent, a first flavoring agent, and a first carrier base; wherein, the first flavoring agent functions as a taste indicator of a serotonergic endpoint of a taste titration of the serotonergic agent for the subject receiving the serotonergic formulation, the serotonergic endpoint indicated to the subject by a change in the flavor of the first flavoring agent, and functioning to remit a deficiency in the subject's serotonin level through a delivery of the serotonergic agent across a blood brain barrier; a dopaminergic formulation comprising a dopaminergic agent, a second flavoring agent, and a second carrier base; wherein, the second flavoring agent functions as a taste indicator of a dopaminergic endpoint of the taste titration of the dopaminergic agent for the subject receiving the dopaminergic formulation, the dopaminergic endpoint indicated to the subject by a change in the flavor of the second flavoring agent, and functioning to remit a deficiency in the subject's dopamine level through a delivery of the dopaminergic agent across the blood brain barrier; and a titration means for facilitating a gradual oral transmucosal delivery of the serotonergic agent or dopaminergic agent to the subject to the serotonergic endpoint or dopaminergic endpoint; wherein, the serotonergic formulation and the dopaminergic formulation function together to remit deficiencies and imbalances in the subject's serotonin and dopamine levels, and the serotonergic endpoint and dopaminergic endpoint indicate an amount of the serotonergic formulation and an amount of the dopaminergic formulation that provides a desired response in the subject using the oral transmucosal delivery while mitigating risk of overdose.