Patent ID: 8366627
Filing Date: 2013-02-05
Classification: A61B

Abstract:
1. A method for computing a series of estimates of a selected cerebrovascular property comprising at least one of a cerebrovascular resistance, an intracranial pressure, and a cerebrovascular compliance, comprising: receiving, at a processor, a series of arterial blood pressure measurements of a particular patient; receiving, at the processor, a series of cerebrovascular flow measurements of the particular patient, the cerebrovascular flow measurements comprising at least one of cerebral blood flow measurements and cerebral blood flow velocity measurements; and computing, with the processor, a series of estimates of the selected cerebrovascular property based at least in part on a corresponding series of estimates of elements of a computational model using the corresponding received measurements, the computational model representing predicted relationships among computational model elements corresponding to physiological properties, including a cerebrovascular resistance element, a cerebrovascular compliance element, an intracranial pressure element, an arterial blood pressure element and a cerebrovascular flow element; wherein computing each estimate in the series of estimates of the selected cerebrovascular property comprises: