Patent ID: 9126951
Filing Date: 2015-09-08
Classification: A61K,A61P,C07D,C07K

Abstract:
1. A method of treating a cancer selected from breast cancer, lung cancer, and liver cancer in a subject, the method comprising administering an effective amount of a compound of Formula I or pharmaceutically acceptable salt thereof, wherein: Ring A is a 3-8 membered aryl, heteroaryl, heterocyclic or alicyclic group; X is CH or N; Y is CH or N—R L is —[C(R each of R two R m is 0-3; n is 4; p is 0-2; and Warhead is selected from the group consisting of wherein X is halo, or triflate; and each of R a , R b , and R c is, independently, H, substituted or unsubstituted C 1-4 alkyl, or substituted or unsubstituted C 1-4 cycloalkyl, to thereby treat the cancer.