Patent ID: 8513405
Filing Date: 2013-08-20
Classification: C07H,C12N

Abstract:
1. A reagent composition for initiating the separation of the nucleic acid DNA from non-nucleic acid substances by initiating the lysis of a cellular source wherein said composition also promotes the adsorption of nucleic acids onto magnetic cellulose paper, particles or beads, the composition comprising an aqueous solution of a chaotropic univalent metal salt and an alcohol or an alcoholic mixture selected from the group consisting of ethanol, isopropanol, and an arbitrarily selected mixture of ethanol and isopropanol, wherein the chaotropic univalent metal salt is selected from lithium chloride (LiCl), sodium acetate (NaOAc), sodium chloride (NaCl), and potassium acetate (KOAc), and further with the optional presence of proteinase K.