Patent ID: 6372907
Filing Date: 2002-04-16
Classification: C07D,C07H,C09B,G01N,Y10S

Abstract:
A labelled rhodamine dye-polypeptide conjugate, or a salt thereof, comprising a rhodamine dye and a polypeptide, whereinthe rhodamine is a rhodamine-type parent xanthene ring having attached to the xanthene C9 carbon a phenyl group that is further substituted with an ortho carboxy or ortho sulfonate group or a salt thereof, one to three substituted or unsubstituted aminopyridinium groups and a substituted or unsubstituted alkylthio, or arylthio group; wherein the rhodamine dye is attached to a location of the polypeptide selected from the amino terminus, the carboxyl terminus, and an amino acid side-chain; and wherein the polypeptide is attached to a location of the rhodamine dye selected from a xanthene ring carbon, the phenyl group attached to the C9 carbon, and a nitrogen atom.