Patent ID: 7504412
Filing Date: 2009-03-17
Classification: A61P,C07D

Abstract:
1. A compound of formula [I] wherein: each R (1) hydrogen (2) halogen (3) C (4) C (5) C (6) di-C (7) C (8) C (9) 3 to 8-membered heterocycloalkyl-C wherein the C 1-6 alkyl moiety may be substituted with R 5 , the cycloalkyl or heterocycloalkyl moiety may be substituted with R 6 , and R 1 and R 2 are not hydrogen at the same time, or R R R each R R W is: wherein those substituents in above (2) through (5) may be optionally substituted with R 5 ; and Ar is an R (1) phenyl, (2) naphthyl, (3) pyridinyl, (4) pyrimidinyl, (5) pyridazinyl, (6) pyrazyl, (7) pyrazole, (8) pyrrolyl, (9) imidazolyl, (10) triazolyl, (11) oxazolyl, (12) isoxazolyl, (13) oxadiazolyl, (14) thiazolyl, (15) isothiazolyl, (16) thiadiazolyl, and (17) tetrazolyl; wherein R 7 is selected from R 5 ; or a pharmaceutically acceptable salt thereof.