Patent ID: 6537977
Filing Date: 2003-03-25
Classification: A61K,A61P,Y10S

Abstract:
A method of treating inflammation in a mammal in need thereof, which comprises administering an effective amount of an anti-inflammatory composition comprising dermatan sulfate or a pharmaceutically acceptable salt thereof as an effective ingredient, and a suitable carrier to said mammal, wherein said dermatan sulfate comprises a content of unsaturated disaccharide having the formula (I): wherein R1, R2, and R3 are each a hydrogen atom, of from 2 to 9% determined by degradation by enzyme to unsaturated dissacharide and high performance liquid chromatography, and wherein said dermatan sulfate has an average molecular weight determined by gel permeation chromatography using a glycosaminoglycan of a known molecular weight as a standard and high performance liquid chromatography of from 25,000 to 100,000 Daltons.