Patent ID: 8647668
Filing Date: 2014-02-11
Classification: A61K

Abstract:
1. A tablet composition which comprises: (a) saccharides comprised of a combination of mannitol and one or more of other saccharide(s) selected from sorbitol, erythritol, maltitol, lactose, and trehalose in an amount of 40 to 90 parts by weight; (b) an inorganic excipient in an amount of 1 to 30 part(s) by weight; and (c) a disintegrating agent in an amount of 5 to 40 parts by weight, wherein a total amount of components (a), (b) and (c) is 100 parts by weight, wherein a weight ratio of mannitol to other saccharide(s) is (98 to 75): (2 to 25), wherein the tablet composition exhibits an oral disintegration time of within 40 seconds, and wherein mannitol and other saccharide(s) form complex particles, which exhibit a melting point depression, and the inorganic excipient and the disintegrating agent are dispersed in the complex particles.