Patent ID: 6432983
Filing Date: 2002-08-13
Classification: A61P,C07D

Abstract:
A compound of formula I wherein:R1 is â€”H, â€”OH, â€”O(C1-C4 alkyl), â€”Oâ€”COâ€”(C1-C6 alkyl), â€”Oâ€”COâ€”O(C1-C6 alkyl), â€”Oâ€”COâ€”Ar in which Ar is optionally substituted phenyl, or â€”Oâ€”SO2â€”(C4-C6 alkyl); R2 is â€”H, â€”OH, â€”O(C1-C4 alkyl), â€”Oâ€”COâ€”(C1-C6 alkyl), â€”Oâ€”COâ€”O(C1-C6 alkyl), â€”Oâ€”COâ€”Ar in which Ar is optionally substituted phenyl, â€”Oâ€”SO2â€”(C4-C6 alkyl), â€”F, â€”Cl, or â€”Br; n is an integer from 5 to 8; R3 and R4 each are independently C1-C4 alkyl, or combine to form, with the nitrogen to which they are attached, piperidinyl, pyrrolidinyl; methylpyrrolidinyl, dimethylpyrrolidinyl, or hexamethyleneimino; or a pharmaceutically acceptable salt or solvate thereof.