Patent ID: 7485296
Filing Date: 2009-02-03
Classification: A01K,A61K,A61P,C07K,G01N

Abstract:
1. A method for treating a patient having pancreatic cancer by inhibiting the growth of a pancreatic cancer cell expressing the Prostate Stem Cell Antigen (PSCA) protein as shown in SEQ ID NO: 2 in the patient, comprising contacting the pancreatic cancer cell with the monoclonal antibody 1G8 (ATCC No. HB-12612), or a fragment thereof that recognizes and binds PSCA as shown in SEQ ID NO:2; an immunoconjugate of the antibody; or the fragment linked to a therapeutic agent; a humanized form of the 1G8 monoclonal antibody; or a fusion protein comprising the fragment of the 1G8 monoclonal antibody in an amount effective to inhibit the growth of the pancreatic cancer cell.