Patent ID: 8883196
Filing Date: 2014-11-11
Classification: A61K,A61P

Abstract:
1. A method of controlling fertility in a female, comprising applying to the skin of the female a transdermal hormone delivery device comprising a backing layer and an adhesive polymer matrix affixed to the backing layer, the adhesive polymer matrix comprising: (a) an adhesive polymer; (b) a humectant; (c) a combination of skin permeation enhancing agents consisting essentially of, on a final percentage by weight of the adhesive polymer matrix after fabrication of the system, from about 4% to about 12% dimethyl sulfoxide; from about 4.2% to about 12.6% a fatty (C (d) a progestin; and (e) an estrogen; wherein the device is applied to the skin in a regimen comprising application of one device once each week for three consecutive weeks, followed by one week in which the device is not applied, or a placebo device is applied, thereby controlling fertility in the female.