Patent ID: 7547705
Filing Date: 2009-06-16
Classification: A61K,A61P,C07D,Y02P

Abstract:
1. A method of inhibiting the activity of glycogen synthase kinase 3-beta (GSK3-β), which comprises administering to a patient in need of said inhibition a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein: X represents two hydrogen atoms, a sulfur atom, an oxygen atom or a C Y represents a bond, a carbonyl group, a methylene group optionally substituted by one or two groups chosen from a C R1 represents a 2, 3 or 4-pyridine ring or a 2, 4 or 5-pyrimidine ring, the rings being optionally substituted by a C R2 represents a benzene ring or a naphthalene ring; the rings being optionally substituted by 1 to 4 substituents selected from a C R3 represents a hydrogen atom, a C R4 represents a hydrogen atom, a C o and m represent 1 to 2; n represents 0 to 3; p represents 0 to 2; and q represents 0 to 2.