Patent ID: 6583134
Filing Date: 2003-06-24
Classification: A61P,C07D

Abstract:
An aza-indolyl derivative selected from the group consisting of a compound of formula (I): whereinn is 1,2 or 3; X1 is nitrogen or CR4; X2 is nitrogen or CR5; X3 is nitrogen or CR6; X4 is nitrogen or CR7; wherein one or two of X1, X2, X3 and X4 are nitrogen; R1, R2 and R3 are independently selected from hydrogen and alkyl; R4, R5, R6 and R7 are independently selected from hydrogen, halogen, hydroxy, alkyl, aryl, alkoxy, aryloxy, alkylthio, arylthio, alkylsulfonyl, alkylsulfoxyl, arylsulfonyl, arylsulfoxyl, amino, monoalkylamino, dialkylamino, nitro, cyano, carboxaldehyde, alkylcarbonyl, arylcarbonyl, aminocarbonyl, monoalkylaminocarbonyl, dialkylaminocarbonyl, alkoxycarbonylamino, aminocarbonyloxy, monoalkylaminocarbonyloxy, dialkylaminocarbonyloxy, monoalkylaminocarbonylamino and dialkylaminocarbonylamino, and wherein for each of X1, X2, X3 and X4 which is nitrogen, adjacent ring atoms selected from the group consisting of X1, X2, X3 and X4 are not substituted by halogen; and pharmaceutically acceptable salts thereof.