Patent ID: 6307103
Filing Date: 2001-10-23
Classification: C07C

Abstract:
In a process for the preparation of a 1,1,1-trifluoro-2-aminoalkane of formula I ##STR5##whereinR.sup.1 represents an optionally substituted alkyl group;which comprises hydrogenating the corresponding oxime of formula II ##STR6##wherein R.sup.1 has the meaning given above and the winding line indicates that the hydroxy group may be in the (E)- or (Z)-position with respect to the trifluoromethyl group, in the presence of Raney nickel in a diluent;wherein the improvement is, that the reaction is carried out in a diluent selected from an alkanol, a cyclic ether and an aromatic hydrocarbon and with the proviso that the 1,1,1-trifluoro-2-aminoalkane is obtained at a yield of greater than thirty percent.