Patent ID: 6407124
Filing Date: 2002-06-18
Classification: C07D

Abstract:
A compound of the formula: or a pharmaceutically acceptable salt thereof wherein:R1=COR3; R3=heteroarylalkyl; R4=alkyl with two or more carbon atoms, cycloalkyl, heterocycloalkyl, cycloalkylalkyl, heterocycloalkylalkyl, aryl, heteroaryl, arylalkyl, heteroarylalkyl, or R9; R5, R6, R7, and R8=independently H, alkyl, cycloalkyl, heterocycloalkyl, cycloalkylalkyl, heterocycloalkylalkyl, aryl, heteroaryl, arylalkyl, heteroarylalkyl, halo, hydroxy, alkoxy, amino, NR12R13, thio, or alkylthio with the proviso that only one such heteroatom group is bonded to any one carbon atom; R10 and R11=independently H, alkyl, cycloalkyl, heterocycloalkyl, cycloalkylalkyl, heterocycloalkylalkyl, aryl, heteroaryl, arylalkyl, heteroarylalkyl, halo, hydroxy, alkoxy, alkylcarbonyloxy, carboxy, alkyloxycarbonyl, amino, NR15R16, carbamoyl, ureido, thio, or alkylthio; and R12, R13, R14, R15, and R16=independently H, alkyl, cycloalkyl, heterocycloalkyl, cycloalkylalkyl, heterocycloalkylalkyl, aryl, heteroaryl, arylalkyl, or heteroarylalkyl.