Patent ID: 8491929
Filing Date: 2013-07-23
Classification: C08F

Abstract:
1. A bioadhesive polymer comprising a polymer backbone comprising repeat units represented by one of the following structural formulae: wherein the polymer backbone is functionalized with residues of at least one compound comprising: a) an aromatic moiety comprising two or more hydroxyl substituents, methoxy substituents, substituents hydrolyzable to hydroxyl substituents, or a combination thereof; and b) a primary or secondary amino moiety; wherein the blood-brain barrier is substantially impermeable to the at least one compound; or a bioadhesive composition comprising a blend of a polymer comprising repeat units represented by one of the following structural formulae: and one or more compounds comprising: a) an aromatic moiety comprising two or more hydroxyl substituents, methoxy substituents, substituents hydrolyzable to hydroxyl substituents, or a combination thereof; and b) a primary or secondary amino moiety; wherein the blood-brain barrier is substantially impermeable to the at least one or more compounds.