Patent ID: 7531672
Filing Date: 2009-05-12
Classification: C07D

Abstract:
1. A process for preparing heterocyclic ketones of the formulae (I) or (Ia) by reacting a heterocyclic compound of the formula (II) with an α,β-unsaturated carboxylic acid of the formula (III) or with its anhydride of the formula (IV) which comprises performing the reaction in a liquid reaction medium which comprises at least one strong organic acid and at least one water absorbent, where the strong organic acid has a higher acid strength than the carboxylic acid of the formula (III) by adding simultaneously the heterocyclic compound of the formula (II) together with the α,β-unsaturated carboxylic acid of the formula (III) or together with its anhydride of the formula (IV) to said liquid reaction medium, and wherein the reaction is carried out in the temperature range from 60 to 90° C., and where R R R R X is an element of the 16th group of the Periodic Table or is a divalent nitrogen group —(N—R