Patent ID: 6541484
Filing Date: 2003-04-01
Classification: A61P,C07D

Abstract:
A compound of formula I, or a salt thereof: whereinY represents hydrogen, C1-6 alkyl, amino, C1-6 alkylamino or di(C1-6)alkylamino; and Z represents hydrogen, C1-6 alkyl, C3-7 cycloalkyl, C4-7 cycloalkenyl, C6-8 bicycloalkyl, aryl, C3-7 heterocycloalkyl, heteroaryl, C2-7 alkoxycarbonyl or di(C1-6)alkylamino, any of which groups may be optionally substituted, with the proviso that Y and Z are not both simultaneously hydrogen; or Y and Z are taken together with the two intervening carbon atoms to form a ring selected from C5-9 cycloalkenyl, C6-10 bicycloalkenyl, tetrahydropyridinyl, pyridinyl and phenyl, any of which rings may be optionally benzo-fused and/or substituted; R1 represents C3-7 cycloalkyl, phenyl, furyl, thienyl or pyridinyl, any of which groups may be optionally substituted; and R2 represents C3-7 cycloalkyl(C1-6)alkyl, aryl(C1-6)alkyl or heteroaryl(C1-6)alkyl, any of which groups may be optionally substituted.