Patent ID: 7531644
Filing Date: 2009-05-12
Classification: A61K,C07K,C12N

Abstract:
1. An IL-6 receptor•IL-6 fusion protein, comprising: (A) an IL-6 receptor represented by the amino acid sequence set forth in SEQ ID NO:63 or a partial sequence of IL-6 receptor that binds to IL-6 wherein the partial sequence of IL-6 receptor has an amino terminus at any one of Leu at the 20 (B) an IL-6 represented by the amino acid sequence of SEQ ID NO:64, or a partial sequence of IL-6 that binds to the IL-6 receptor of (A) wherein the partial sequence of IL-6 has an amino terminus at any one of Ala at the 28 wherein (A) and (B) are linked via a peptide bond from the carboxy terminus of (A) to the amino terminus of (B)—, and wherein said fusion protein induces gp130 for signal transmission.