Patent ID: 8133978
Filing Date: 2012-03-13
Classification: A61K,A61P,C07K

Abstract:
1. A humanised anti-interleukin-18 antibody comprising a heavy chain and light chain comprising the following complementarity determining regions (CDRs): CDRH1: SEQ ID NO:1; CDRH2: SEQ ID NO:2; CDRH3: SEQ ID NO:3; CDRL1: SEQ ID NO:4; CDRL2: SEQ ID NO:5; and CDRL3: SEQ ID NO:6, wherein said antibody comprises a heavy chain selected from the group consisting of: SEQ ID NO: 9, SEQ ID NO: 17, and SEQ ID NO: 21; and a light chain selected from the group consisting of: SEQ ID NO: 13 and SEQ ID NO: 29.