Patent ID: 6458822
Filing Date: 2002-10-01
Classification: A61P,C07D

Abstract:
A compound according to formula (1) or a pharmaceutically acceptable salt or solvate thereof, whereinR1 is (C6-C10)aryl, (C6-C10)aryl(C1-C6)alkyl , (C6-C10)aryl(C6-C10)aryl , (C6-C10)aryloxy(C6-C10)aryl, (C6-C10)aryloxy(C1-C6)alkyl, (C6-C10)aryl(C1-C6)alkyl (C6-C10)aryl,(C6-C10)aryl(C1-C6)alkoxy(C6-C10)aryl, (C6-C10)aryloxy(C1-C6)alkyl(C6-C10)aryl, (C6-C10)aryl(C6-C10)aryl(C1-C6)alkyl, or (C6-C10)aryl(C1-C6)alkoxy(C1-C6)alkyl, wherein, independently, each of the ring carbon atoms of said (C6-C10)aryl moieties that is capable of forming an additional bond is optionally substituted by a group selected from fluoro, chloro, bromo, (C1-C6)alkyl, (C1-C6)alkoxy, and perfluoro(C1-C3)alkyl, and perfluoro(C1-C3)alkoxy; R2 and R3are each independently selected from hydrogen and (C1-C6)alkyl, and R4 is hydrogen or (C1-C6)alkyl.