Patent ID: 6107511
Filing Date: 2000-08-22
Classification: C07C,Y02P

Abstract:
A method of purifying and isolating an N-protected (2S,3R)-1-halo-2-hydroxy-3-amino-4-phenylthiobutane of the general formula (1): ##STR6## (wherein X represents a halogen atom; one of P.sup.1 and P.sup.2 represents a hydrogen atom and the other represents an amino-protecting group, or P.sup.1 and P.sup.2 taken together represents an amino-protecting group) or its enantiomer, which comprises using an aromatic hydrocarbon solvent to remove an impurity occurring in said compound of general formula (1) or an impurity occurring in said enantiomer from said compound of general formula (1) containing impurities or its enantiomer containing impurities and isolate said compound of general formula (1) or said enantiomer as crystals.