Patent ID: 8394029
Filing Date: 2013-03-12
Classification: A61B,A61N

Abstract:
1. A monitoring device for monitoring and analyzing physiological signals comprising: a transthoracic impedance measurement unit; an evaluation unit connected to said transthoracic impedance measurement unit; said transthoracic impedance measurement unit configured to conduct a transthoracic impedance measurement and to generate a transthoracic impedance signal that represents a measured transthoracic impedance at consecutive points in time; said evaluation unit configured to process said transthoracic impedance signal received from said transthoracic impedance measurement unit and to thus generate a respiration signal and to generate therefrom an evaluation signal that reflects at least a diurnal pattern of a respiration rate; a sensing unit configured to process an EGM signal that represents intracardiac myocardial electric potentials and determine therefrom a heart rate signal; wherein said evaluation unit is configured to perform a trending analysis of multiple different physiological parameters, comprising a heart rate, a heart rate variability and said respiratory rate; wherein said evaluation unit is configured to determine overall statistics of a respiration rate signal; and, wherein said evaluation unit is configured to determine a composite score from said multiple different physiological parameters; wherein said evaluation unit is configured to determine said composite score as follows: where a, b, c, and d are predefined non-negative coefficients, rRR is a resting respiration rate, dRR is a difference between day and night respiration rates, rHR is a resting heart rate, and HRV is an index of 24-hour heart rate variability.