Patent ID: 8389207
Filing Date: 2013-03-05
Classification: A01K,C07K,C12N

Abstract:
1. A method of identifying an agent having potential to mobilize fat stores in a subject, comprising: (i) contacting a test system comprising a TRB3 polypeptide with at least one test agent, wherein the test system is selected from a non-human animal, an isolated tissue, an isolated cell or an isolated TRB3 polypeptide; (ii) following contact of the at least one test agent with the test system, detecting: wherein expression of the nucleic acid encoding the TRB3 polypeptide is increased at least 10% relative to expression of the nucleic acid encoding the TRB3 polypeptide prior to addition of the test agent; (iii) identifying the at least one test agent as an agent having potential to mobilize fat stores in a subject.