Patent ID: 8361790
Filing Date: 2013-01-29
Classification: C12N

Abstract:
1. A cell generated from fusion of a cell of human embryonic kidney origin and a cell of human B-cell origin, wherein the cell of human embryonic kidney origin is a 293 cell, and wherein the cell of human B-cell origin is a Namalwa cell that has an Epstein-Barr virus (EBV) genome inserted into its chromosomes, wherein the generated cell i) constitutively expresses EBNA1 proteins; ii) does not express IgM proteins; iii) continuously generates glycosylation profiles similar to those of humans; and iv) expresses BALF1, but does not express BHRF1, wherein the growth of the generated cell is not inhibited when sodium butyrate is added to a culture medium for the generated cell.