Patent ID: 6265535
Filing Date: 2001-07-24
Classification: A61K,C07K,Y02A

Abstract:
A compound having the formula: ##STR7##wherein:B.sub.1 and B.sub.10 are each independently a peptide of 1-6 amino acids, at least one of which is a hydrophobic amino acid, an aromatic moiety, or a heteroaromatic moiety;Z.sub.2 is a moiety that is capable of forming a covalent linkage with B.sub.1, X.sub.3, and Z.sub.9 ;Z.sub.9 is a moiety that is capable of forming a covalent linkage with B.sub.10, X.sub.8, and Z.sub.2 ;X.sub.3 is absent or a hydrophilic amino acid;X.sub.4 is a hydrophobic amino acid;X.sub.5 is a hydrophilic amino acid;X.sub.6 is a hydrophilic amino acid;X.sub.7 is a hydrophobic or hydrophilic amino acid;X.sub.8 is a hydrophobic amino acid;""--"" is an amide, substituted amide, or an isostere of amide thereof;"".dbd."" is a covalent linkage; and"".ident."" is a covalent linkage.