Patent ID: 8834549
Filing Date: 2014-09-16
Classification: A61F,A61L,Y10S

Abstract:
1. A drug eluting interventional device produced by a method comprising: providing an interventional device having a bare surface; mixing at least one therapeutic agent and at least one polymer in a solvent to form a mixture, wherein the at least one polymer includes phosphorylcholine; applying the mixture to at least a portion of the bare surface of the interventional device to form a coating thereon, wherein no base coating is applied to the surface of the interventional device; and crosslinking the at least one polymer by sterilizing the coated interventional device, wherein crosslinking the at least one polymer comprises exposing the coated interventional device to multiple complete cycles of ethylene oxide sterilization, and wherein crosslinking the at least one polymer increases retention of the at least one therapeutic agent on the interventional device as compared to a substantially identical interventional device subject to crosslinking of the at least one polymer by exposure to a single complete cycle of ethylene oxide sterilization.