Patent ID: 7767205
Filing Date: 2010-08-03
Classification: A61K,A61P,C07K

Abstract:
1. An isolated anti-EphB2 antibody comprising (i) a light chain comprising: (a) HVR-L1 comprising a sequence of SEQ ID NO: 1; (b) HVR-L2 comprising a sequence of SEQ ID NO: 2; (c) HVR-L3 comprising a sequence of SEQ ID NO: 3; and (ii) a heavy chain comprising (a) HVR-H1 comprising a sequence of SEQ ID NO: 4; (b) HVR-H2 comprising a sequence of SEQ ID NO: 5; and (c) HVR-H3 comprising a sequence of SEQ ID NO: 6, wherein the antibody specifically binds human EphB2.