Patent ID: 6521666
Filing Date: 2003-02-18
Classification: A61P,C07C,C07D

Abstract:
A compound of the formula [I]: whereinRing A is a benzene ring; Q is a bond; N is an integer of 1 or 2; W is a â€”CH&boxH;CHâ€” group; Z is oxygen atom or sulfur atom; R1, R2, and R3 are the same or different and are selected from the group consisting of: hydrogen atom, halogen atom, a substituted or unsubstituted lower alkoxy group, a nitro group, a substituted or unsubstituted amino group, a carboxyl group or an amide or an ester thereof, a cyano group, a lower alkylthio group, a lower alkanesulfonyl group, a substituted or unsubstituted sulfamoyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted heterocyclic group, and hydroxyl group, or two of R1, R2, and R3 may combine each other at the terminal thereof to form a lower alkylenedioxy group; R4 is a carboxyl group, or an amide or an ester thereof; R5 is a group selected from the group consisting of: hydrogen atom, a nitro group, a substituted or unsubstituted amino group, a hydroxyl group, a lower alkanoyl group, a substituted or unsubstituted lower alkyl group, a lower alkoxy group, a halogen atom, and 2-oxopyrrolidinyl group; R6 is a substituted or unsubstituted phenyl group; or a pharmaceutically acceptable salt thereof.