Patent ID: 6333020
Filing Date: 2001-12-25
Classification: A61K,A61P,Y10S

Abstract:
A method for treating an arteriovenous malformation (AVM) in a mammal which method comprises:(a) selecting a fluidic composition comprising a biocompatible polymer, a biocompatible solvent which solubilizes said polymer and a water insoluble radioisotope wherein said biocompatible solvent is selected from the group consisting of dimethylsulfoxide, ethanol, ethyl lactate and acetone; and(b) injecting an effective amount of said composition into one or more vascular sites of said mammal which lead to or are within the AVM under conditions wherein a solid mass is formed which solid mass ablates at least part of the AVM wherein said solid mass comprises the water insoluble polymer and the radioisotopeand further wherein the radioactivity of the radioisotope is employed in an amount effective to inhibit regrowth of the AVM and to further ablate the AVM.