Patent ID: 6943034
Filing Date: 2005-09-13
Classification: B01J,B82Y,C07B,C07H,C07K,C40B,G01N,Y10S,Y10T

Abstract:
1. A method of forming an array of ligands on a support having localized areas comprising (a) locating a dispenser to dispense a solution comprising a compound a distance away from a surface of the support; (b) dispensing a volume of the solution in a single coupling step of less than 5 nl from the dispenser to occupy a localized area smaller than 1 cm (c) allowing the compound to attach directly or indirectly to the surface of the support at the localized area; (d) repeating steps a through c to attach a same or different compound at a same or different localized area until an array of at least 100 different ligands, each at an individual localized area is formed and wherein density of localized areas on the support is at least about 1000 localized areas per cm