Patent ID: 6297272
Filing Date: 2001-10-02
Classification: C07D

Abstract:
An artemisinin dimer having the structure: ##STR18##wherein said dimer is an [E,E], [E,Z] or [Z,Z] dimer, wherein R isalkylene,alkylene comprising one or more substituents,heteroalkylene,alkenylene,alkenylene comprising one or more substituents,alkynylene,arylene,arylene comprising one or more substituents,heteroarylene, orheteroarylene comprising one or more substituents,wherein said substituents are selected from the group comprising halogen, NO.sub.2, OH, SH, lower alkoxy, lower alkyl, NHC(=O)R.sub.1, NH.sub.2, COOH, C(=O)NH.sub.2, and COOR.sub.2, wherein R.sub.1 is aryl or lower alkyl and R.sub.2 is aryl or lower alkyl.