Patent ID: 6447749
Filing Date: 2002-09-10
Classification: A61K

Abstract:
A compound of formula IRfâ€”Lâ€”Aâ€ƒâ€ƒ(I) whereinRf is a straight-chain or branched perfluoroalkyl radical having 4 to 30 carbon atoms, L is a linker and A is a dye molecule according to formula II, whereinD is a group of formula III, IV, V or VI, wherein the star denotes the linkage point with B, B is a group of formula VII, VIII, IX, X, XI or XII, whereinR1 and R2 are, each independently, a C1-C4 sulfoalkyl chain, or a saturated or unsaturated, branched or straight-chain C1-C50 alkyl chain, wherein the alkyl chain or one or more parts of this chain optionally forms one or more aromatic or saturated, cyclic C5-C6 units or bicyclic C10 units, and wherein the C1-C50 alkyl chain optionally comprises 0 to 15 â€”Oâ€” groups and/or 0 to 3 carbonyl groups and is optionally substituted with 0 to 5 hydroxy groups, R3 is a â€”COOE1, CONE1E2, â€”NHCOE1, â€”NHCONHE1, â€”NE1E2, â€”OE1, â€”OSO3E1, â€”SO3E1, â€”SO2NHE1 or â€”E1 radical, E1 and E2 are, independently of one another, a hydrogen atom, a C1-C4 sulfoalkyl chain, or a saturated or unsaturated, branched or straight-chain C1-C50 alkyl chain, wherein the alkyl chain or one or more parts of this chain optionally forms one or more aromatic or saturated cyclic C5-C6 units or bicyclic C10 units, and wherein the C1-C50 alkyl chain optionally comprises 0 to 15 â€”Oâ€” groups and/or 0 to 3 carbonyl groups, and is optionally substituted with 0 to 5 hydroxy groups, R4 is a hydrogen fluorine, chlorine, bromine or iodine atom, or a branched or straight-chain C1-C10 alkyl chain, b is 2 or 3, and X and Y are, independently of one another, â€”CH&boxH;CHâ€” or C(CH3)2.