Patent ID: 8279434
Filing Date: 2012-10-02
Classification: G01N,G06K

Abstract:
1. A method for optical-spectroscopic analysis of a biological sample in liquids, comprising: fixation of the biological sample in a sample holding unit; categorization of any particles contained in the biological sample by analysis of photomicrograph image data of the biological sample and/or particles contained in the biological sample; and Raman spectroscopic analysis of the biological sample within a measurement zone that can be positioned in the area of the biological sample; wherein the measurement zone is automatically positioned on certain sections or particles of the biological sample based on results of the categorization according to established criteria and the Raman spectroscopic analysis is restricted to the area of the measurement zone wherein a reversible fixation of the biological sample occurs by allowing the biological sample to flow through the sample holder unit, in which any particles contained in the biological sample are retained in the measurement zone and reversibly fixed there at least for the duration of the analysis, wherein the biological sample is a biological fluid and the sample holder unit is designed as a fluid cell; and wherein the particles in the fluid cell are retained by at least one perforated plate arranged in a fluid cell with one or more perforations.