Patent ID: 8828968
Filing Date: 2014-09-09
Classification: A61K,A61P

Abstract:
1. A preparation for treating gastric cancer or hepatoma, comprising nanoparticles of glucidamin and a pharmaceutically acceptable carrier, wherein said glucidamin is derived from an organism, a viscosity-average molecular weight of the glucidamin is in a range of 1×10 3 -9×10 5 , and an amount of free amino groups in the glucidamin is in a range of 50%-100% based on the total amount of amino groups in the glucidamin, wherein the preparation includes the nanoparticles of glucidamin in an amount sufficient for treating gastric cancer or hepatoma in a subject in need thereof, and wherein the preparation is obtained by (1) adding the glucidamin into a diluted acid solution at 20-60° C. to form a polysaccharide solution, wherein an amount of the polysaccharide in the polysaccharide solution is in a range of 0.1%-5% by weight; (2) adjusting a pH of the polysaccharide solution obtained in (1) to 6-9 in order to form an emulsion of microparticles; and (3) separating the microparticles from the emulsion obtained in (2), and (4) drying the separated microparticles obtained in (3) at low temperature to obtain the preparation.