Patent ID: 6444826
Filing Date: 2002-09-03
Classification: C07C,C07D,C07F

Abstract:
A compound of the formula or the enantiomer of said compound, wherein X is attached at position 4 or 5 of the phenyl moiety; R1 is â€”(CH2)qCHR5R6 wherein q is 0 to 4; each R2 is independently selected from the group consisting of H, fluoro, chloro, C1-C6 alkyl, C1-C6 alkoxy, phenylsulfinyl, phenylsulfonyl, and â€”S(O)n, (C1-C6 alkyl) wherein n is 0 to 2, and wherein said alkyl group, the alkyl moiety of said alkoxy and â€”S(O)n(C1-C6 alkyl) groups, and the phenyl moiety of said phenylsulfinyl and phenylsulfonyl groups are optionally substituted by 1 to 3 fluoro groups; R5 is H, C1-C6 alkyl, or phenyl substituted by R2; R6 is H, C1-C6 alkyl, C3-C8 cycloalkyl, C6-C10 aryl, or 5-10 membered heteroaryl, wherein said aryl and heteroaryl groups are optionally substituted by 1 or 2 substituents independently-selected from phenyl, R2, and phenyl substituted by 1 or 2 R2; X is halo; Y is halo or nitro; and, Xc is a chiral auxiliary.