Patent ID: 6552007
Filing Date: 2003-04-22
Classification: A61K,A61P

Abstract:
A compound comprising a somatostatin analog moiety, a spacer moiety and an anti-cancer drug moiety, said spacer moiety is selected from the group consisting ofâ€”COâ€”(â€”CH2CH2Oâ€”)nâ€”CH2CH2â€”COâ€”; â€”COâ€”(â€”CH2CH2Oâ€”)nâ€”CH2CH2â€”COâ€”; â€”NHâ€”(â€”CH2CH2Oâ€”)nâ€”CH2CH2â€”COâ€”; â€”NHâ€”(â€”CH2â€”)nâ€”COâ€”; â€”Sâ€”(â€”CH2CH2Oâ€”)nâ€”CH2CH2â€”COâ€”; â€”Sâ€”(â€”CH2â€”)nâ€”COâ€”NH-peptide; â€”(â€”CH2CH2Oâ€”)nâ€”CH2CH2â€”COâ€”; and -maleimide-(â€”CH2â€”)nâ€”COâ€”; where n=1-7.