Patent ID: 7781607
Filing Date: 2010-08-24
Classification: A61P,C07F,C08G,Y02P

Abstract:
1. A method for producing a coordination compound through reaction of a platinum complex with a polymer having carboxyl groups on its side chains, wherein a diaquoplatinum complex or a bis(nitrato)platinum complex and a dihalo-platinum complex which is selected from dichloro-, diiodo- or dibromo-platinum complexes are used in mixed state as the platinum complex, wherein the mixed state is formed by adding a halide ion selected from the group consisting of chloride, iodide and bromide ions to an aqueous solution of bis(nitrato)platinum complex or by adding a halide ion selected from the group consisting of chloride, iodide and bromide ions to aqueous solution of bis(nitrato)(1,2-cyclohexanediamine)platinum(II), and a block copolymer represented by the following general formula (1) or (2): wherein R the method comprising a step of carrying out the reaction in an aqueous medium under the conditions in which the platinum complexes and the block copolymer mutually form a coordination compound, and a step of recovering the so formed coordination compound from the reaction mixture.