Patent ID: 6096340
Filing Date: 2000-08-01
Classification: A61K,A61P

Abstract:
A stable pharmaceutical composition of omeprazole for oral administration that consists of:(a) an inert core;(b) a drug layer surrounding the inert core consisting of 20-70 wt % of omeprazole, 0.1-5 wt % of a surface active agent, 20-70 wt % of a filler, 1-20 wt % of a pharmaceutically acceptable alkaline agent and 0.1-5 wt % of a binder; and(c) a coating layer surrounding the drug layer that consists essentially of an enteric coating agent and an inert processing aid wherein the coating layer is applied directly to the omeprazole containing drug layer without a separating layer between the omeprazole containing drug layer and the coating layer.