Patent ID: 7285669
Filing Date: 2007-10-23
Classification: C07D

Abstract:
1. A method of making 2,6-diamino-4,5,6,7-tetrahydro-benzothiazole, which method comprises the steps in sequence of: (i) reacting bromine with a solution of 4-acetamido-cyclohexanone in water to produce 2-bromo-4-acetamido-cyclohexanone; (ii) adding thiourea to produce 6-acetylamino-2-amino-4,5,6,7-tetrahydro-benzothiazole; (iii) adding an aqueous solution of hydrobromic acid to produce 2,6-diamino-4,5,6,7-tetrahydro-benzothiazole; and (iv) isolating 2,6-diamino-4,5,6,7-tetrahydro-benzothiazole.