Patent ID: 7745656
Filing Date: 2010-06-29
Classification: A61L,A61P,C07C

Abstract:
1. A compound containing at least one S-nitrosyl group and at least one free thiol group, wherein the free thiol group stabilizes the S-nitrosyl group, and optionally one or more functional groups selected from the group consisting of alcohols, amides, thioamides, aldehydes, ketones, halogens, double bonds, triple bonds and aryl groups, wherein the compound has a molecular weight greater than about 375 atomic mass units, wherein at least one free thiol is located within three covalent bonds of at least one S-nitrosyl group, with the proviso that the compound is not an S-nitrosylated derivative of a polypeptide, a polythiolated polysaccharide, or a polymer with pendant thiol groups and is not an S-nitrosylated derivative of a compound represented by one of the following structural formulas: wherein each Ra is —H or methyl and is independently chosen.