Patent ID: 6500797
Filing Date: 2002-12-31
Classification: C07C,C11D

Abstract:
A process for preparing a &bgr;-ketoester fragrance pro-accord comprising the steps of:a) reacting in the presence of a base a 1,3-dioxane-4,6-dione having the formula: wherein R1 and R2 are each independently C1-C10 alkyl, C2-C10 alkenyl, C7-C22 alkylenearyl, C6-C10 aryl, and mixtures thereof; with an activated acyl group having the formula: wherein R3, R4, and R5 are each independently hydrogen, C1-C30 substituted or unsubstituted linear alkyl, C3-C30 substituted or unsubstituted branched alkyl, C3-C30 substituted or unsubstituted cyclic alkyl, C1-C30 substituted or unsubstituted linear alkoxy, C3-C30 substituted or unsubstituted branched alkoxy, C3-C30 substituted or unsubstituted cyclic alkoxy, C2-C30 substituted or unsubstituted linear alkenyl, C3-C30 substituted or unsubstituted branched alkenyl, C3-C30 substituted or unsubstituted cyclic alkenyl, C2-C30 substituted or unsubstituted linear alkynyl, C3-C30 substituted or unsubstituted branched alkynyl, C6-C30 substituted or unsubstituted alkylenearyl; or R3, R4, and R5 can be taken together to form C6-C30 substituted or unsubstituted aryl; and mixtures thereof; X is an acyl activating unit; to form an acyl 1,3-dioxane-4,6-dione, the enol tautomer of which having the formula: b) optionally, isolating said acyl 1,3-dioxane-4,6-dione; and c) reacting said acyl 1,3-dioxane-4,6-dione from step (a) or (b) with a fragrance raw material alcohol having the formula: ROH wherein R is selected from the group consisting of C8 or higher alkyl, alkenyl, alkynyl, aryl, alkylaryl, alkylheteroaryl and heteroaryl moieties; said moieties being linear or branched, and substituted or unsubstituted; to form a &bgr;-ketoester fragrance pro-accord having the formula: wherein R3, R4, and R5 are as defined herein above.