Patent ID: 7834052
Filing Date: 2010-11-16
Classification: A61P,C07D

Abstract:
1. A compound of formula (1a): wherein R R R R R R′ is heterocyclyl or cycloalkyl; n is 0, 1 or 2; where alkyl or cycloalkyl is unsubstituted or substituted by one or two of the same or different groups selected from: halogen, hydroxy, alkylcarboxy, amino, cycloalkyl, alkoxy, aryloxy, alkoxylcarbonyl, arylalkoxycarbonyl, aminocarbonyl, alkylamino, dialkylamino, cycloalkylamino, cycloalkyl alkylamino, heterocyclyl alkylamino, heteroarylamino, heteroarylalkylamino, dialkylamino, alkylamino, aryl, amino aryl, heteroaryl and heterocyclyl; heterocyclyl is unsubstituted or substituted by one or two of the same or different groups selected from: halogen, hydroxy, alkoxy, oxo, alkyl, cycloalkyl, cycloalkyl alkyl, aryl, hydroxyalkyl, amino, aminoalkyl, alkylaminoalkyl, heterocyclyl alkyl, heteroaryl alkyl, aralkyl, alkylheteroaryl, cycloalkylheteroaryl, formyl, alkylcarbonyl, alkoxycarbonyl, aryl alkoxycarbonyl, cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, —SH, —S-alkyl, —S(O) aryl is unsubstituted or substituted by one or two of the same or different groups selected from: halogen, nitro, alkyl, trifluoromethyl, alkoxy, amino, mono- or di-alkylamino, heteroaryl alkyl and aralkyl; heteroaryl is unsubstituted or substituted by one or two of the same or different groups selected from: halogen, alkyl, cycloalkyl, nitro and amino; W is S(O) m is 1 or 2; in all its stereoisomeric and tautomeric forms and mixtures thereof in all ratios, and its pharmaceutically acceptable salts and solvates.