Patent ID: 6964980
Filing Date: 2005-11-15
Classification: A61K,A61P

Abstract:
1. A method for promoting wound healing in mammals, which method comprises administering to a mammal in need of such treatment an effective amount of a compound of the formula: or a pharmaceutically acceptable salt thereof wherein A is a C Z is a bond, O, S, C(O)NH, or C R R R R and Ar represents a phenyl group optionally substituted with up to 5 groups independently selected from halogen, an alkyl group of 1-6 carbon atoms, an alkyl group of 1-6 carbon atoms substituted with one or more halogens, nitro, OR a heterocyclic 5-membered ring having one nitrogen, oxygen or sulfur, two nitrogens one of which is optionally replaced by oxygen or sulfur, or three nitrogens one of which is optionally replaced by oxygen or sulfur, said heterocyclic 5-membered ring substituted by one or two fluoro, chloro, (C a heterocyclic 6-membered ring having one to three nitrogen atoms, or one or two nitrogen atoms and one oxygen or sulfur, said heterocyclic 6-membered ring substituted by one or two (C said benzo-condensed heterocyclic 5-membered or 6-membered rings optionally substituted in the heterocyclic 5-membered or 6-membered ring by one of fluoro, chloro, bromo, methoxy, or trifluoromethyl; oxazole or thiazole condensed with a 6-membered aromatic group containing one or two nitrogen atoms, with thiophene or with furane, each optionally substituted by one of fluoro, chloro, bromo, trifluoromethyl, methylthio or methylsulfinyl; imidazolopyridine or triazolopyridine optionally substituted by one of trifluoromethyl, trifluoromethylthio, bromo, or (C thienothiophene or thienofuran optionally substituted by one of fluoro, chloro or trifluoromethyl; thienotriazole optionally substituted by one of chloro or trifluoromethyl;