Patent ID: 6057374
Filing Date: 2000-05-02
Classification: A61K,A61N

Abstract:
A device for delivering a beneficial agent through a body surface of a patient by electrotransport, the device comprising a source of electrical power, a donor electrode and a counter electrode in electrical communication with the source of electrical power and a donor reservoir in electrical communication with the donor electrode, said donor reservoir being substantially non-hydrated until the device is to be placed in operation and containing the beneficial agent and a permeation enhancer in an amount effective to increase the electrotransport of said beneficial agent, said permeation enhancer being selected from the group consisting of i) and ii) wherein i) is selected from the group consisting of dodecanol, 1,2-dodecane diol, octyl-N,N,-dimethyldodecylamino salts, 1-methyl-4-imidazoline-2-one-3-propylenedodecanoate, N,N-dimethyldodecylamine, a dodecylpyridinium salt, and mixtures thereof, and ii) is compounds having the chemical formula: ##STR7## wherein R.sub.3 is a saturated C.sub.8 -C.sub.9 hydrocarbon; n1 is an integer from 1 to 50; andR.sub.2 is H or CH.sub.3.