Patent ID: 8329445
Filing Date: 2012-12-11
Classification: A61K,C06B,C07C,C12N,C12P,Y02A

Abstract:
1. A process for producing anabolic phloroglucinol, comprising the steps of (A) providing (1) an isolated recombinant cell comprising a phloroglucinol synthase having the amino acid sequence of SEQ ID NO: 2, wherein the isolated recombinant cell does not express other active enzymes involved in the acetylphloroglucinol synthesis pathway, the recombinant cell being capable of converting malonyl-CoA to phloroglucinol; and (2) malonyl-CoA; and (B) contacting the malonyl-CoA with the recombinant cell under conditions in which phloroglucinol can be synthesized therefrom; thereby producing anabolic phloroglucinol.