Patent ID: 8314211
Filing Date: 2012-11-20
Classification: A61B,A61L,A61P

Abstract:
1. A method of sealing injured tissue of a patient's body that utilizes a four-part hemostatic composition including a hydrogel carrier and a fibrin monomer, in combination, for cessation of blood loss from the injured tissue without application of a compressive force independently therefrom, the method comprising the steps of: (a) mixing in a mixing device the following components so as to create a foam: (b) delivering the foam through an outlet of the mixing device to a surgical site of a body cavity, organ or tissue so as to place the foam in contact with the site such that the non-dynamic, non-crosslinked fibrin monomer of the foam sticks to wet tissue of the site and forms a matrix in the patient's blood; wherein the mixing of Parts A, B, C, and D renders the non-crosslinked fibrin monomer dynamic by neutralizing the pH of the overall mixture such that the non-crosslinked fibrin is converted to a fibrin sealant, thereby inducing coagulation of the blood and adhesive properties of severed tissue.