Patent ID: 6232313
Filing Date: 2001-05-15
Classification: A61P,C07D

Abstract:
Any compound of formula II or a tautomer thereof or a pharmaceutically-acceptable salt thereof: ##STR9##wherein:A is a ring-structure selected from either unsubstituted phenyl or pyridyl or from phenyl or pyridyl mono- or di-substituted with R.sup.4 ;R.sup.1 is --(CH.sub.2).sub.n L where n is an integer selected from the range 0 to 6, and:L is selected from unsubstituted phenyl, or phenyl substituted with 1, 2, 3 or 4 groups independently selected at each occurrence from OH, halo, NO.sub.2, CN, COOH, CONH.sub.2, tetrazole, C.sub.1-4 alkoxy, SO.sub.q C.sub.1-4 alkyl where .sub.q is 0, 1 or 2, C.sub.1-4 alkyl, C.sub.1-4 perhaloalkyl, C.sub.1-4 perhaloalkoxy, C.sub.1-4 alkoxyphenyl, CON(C.sub.1-4 alkyl).sub.2 and C(O)OC.sub.1-4 alkyl, andR.sup.4 at each occurrence is independently selected from halogen and NO.sub.2 ;with the proviso that when n is 1, 2, 3 or 4, L is not unsubstituted phenyl, or phenyl substituted with groups independently selected at each occurrence from OH, halo, NO.sub.2, CN, C.sub.1-4 alkoxy or C.sub.1-4 alkyl.