Patent ID: 6489365
Filing Date: 2002-12-03
Classification: A61P,C07C,C07D

Abstract:
A compound of the formula wherein R1 is COR6, R2 is R7, OR7, COR6 or halogen, R3 is halogen, R7, OR7, COâ€”(C1-4-alkyl), NHâ€”COâ€”(C1-4-alkyl), NHSO2â€”(C1-4-alkyl) or N(R10)2 or a heterocyclic five-membered ring such as: R6 is C1-12-alkyl, phenyl or phenyl optionally substituted by halogen, C1-4-alkyl, C1-4-alkoxy or C2-C5-acyl, R7 is H or C1-12-alkyl, R10 is H or C1-4-alkyl; and A is Oâ€”A1â€”O, wherein A1 is C2-4-alkylene, a racemate thereof, an enantiomer thereof, a pair of diastereomers thereof, in cis- or trans-form thereof, a free base thereof, or a physiologically acceptable salt thereof.