Patent ID: 6387911
Filing Date: 2002-05-14
Classification: A61P,C07D

Abstract:
A compound having the formula: whereinA is n=0-1; R is hydrogen, R2 is hydrogen, C1-4 alkyl, CF3, halogen, cyano, or cyclo C3-7 alkyl; R3, P7, R8, and R13 are independently chosen from hydrogen, halogen, C1-4 alkyl; R14 and R15 are independently chosen from hydrogen, C1-2 alkyl, and C1-2 alkyl substituted with OR16 or COOR16, wherein R16 is hydrogen or C1-4 alkyl; and R4, R5 and R6 are independently chosen from hydrogen, halogen, hydroxy, C1-4 alkyl, C1-4 alkoxy, cyano, CF3O, CHF2O, CF3CH2O, SR10, SOR10, SO2R10, OR11, SR11, NHR11 wherein R10 is C1-4 alkyl unsubstituted or substituted with C(CH3)2NH2, C(CH3)2OH, C(CH3)2NHCOCF3, or CF3, and R11 is phenyl unsubstituted or substituted with one or more of C1-4 alkyl, C1-4 alkoxy, halogen, hydroxy, COOH, CONH2, CH2OH, or CO2R12, wherein R12 is C1-4 alkyl.