Patent ID: 7731756
Filing Date: 2010-06-08
Classification: A61L

Abstract:
1. Biocompatible implant for the treatment of defects in a living organism such as bone defects or tooth extraction wounds, comprising at least one zone of impermeability to soft tissue and/or epithelial cells in-growth, wherein said implant is comprised of an open porous scaffold and a membrane covering at least a part of said scaffold and being sealed to it such that said scaffold and said membrane form a single piece of matter that is resorbable by an organism, wherein at least a portion of the open porous scaffold allows an in-growth of regenerating bone tissue, wherein said scaffold is comprised of fused, biocompatible, biodegradable granules selected from the group consisting of solid granules, porous granules, hollow granules, hollow granules with at least one opening in the granule, and a mixture thereof; said granules having an equivalent-diameter in a range between about 100 μm to about 2000 μm, a major portion of said granules being coated with at least one biocompatible and biodegradable layer of a polymer selected from the group consisting of poly(α-hydroxyesters), poly(ortho esters), poly(ether esters), polyanhydrides, poly(phosphazenes), poly(propylene fumarates), poly(ester amides), poly(ethylene fumarates), poly(amino acids), polysaccharides, polypeptides, poly(hydroxy butyrates), poly(hydroxy valerates), polyurethanes, poly(malic acid), polylactides, polyglycolides, polycaprolactones, poly(glycolide-co-trimethylene carbonates), polydioxanones, and copolymers, terpolymers thereof, and blends thereof; and said polymer coating having a thickness in a range between 1 μm to 300 μm.