Patent ID: 6197599
Filing Date: 2001-03-06
Classification: C40B,G01N,Y10S

Abstract:
A method for identifying an interactions between a single first test protein and one or more of a plurality of different second test proteins, said method comprising the steps of:immobilizing a plurality of antibodies on a solid support, wherein a different antibody directed against each of said second test proteins is provided at known, predetermined positions on said support such that each of said antibodies can be identified by the position where it is immobilized;preparing a mixture containing said first test protein and said plurality of second test proteins under conditions to permit interaction between said first test protein and said second test protein to occur;applying said mixture to said solid support with immobilized antibodies and incubating under conditions to permit binding of said second test proteins thereto;detecting the positions of said first test protein on said solid support thereafter;identifying the second test protein from the positions where said first test protein is detected, whereby the interaction between said first test protein and the one or more of said second test proteins is identified.