Patent ID: 6117986
Filing Date: 2000-09-12
Classification: C07H

Abstract:
A derivatized pyrimidine compound having the structure ##STR10## wherein Pyr represents a pyrimidine substituted at the 5 position with a linker L and said linker comprising at least three carbon atoms and is linking the pyrimidine with the quencher;wherein Q is a quencher andwhenever x is an activated phosphorus group capable of intermolecular bond formation with a 3' hydroxyl of another nucleotide, then y is a protected hydroxyl group and z is --H, --F, --OCH.sub.3, --O-allyl or a protected hydroxyl or amine group andwhenever y is an activated phosphorus group capable of intermolecular bond formation with a 5' hydroxyl of another nucleotide then x is a protected hydroxyl group and z is --H, --F, --OCH.sub.3, --O-allyl or a protected hydroxyl or amine group.