Patent ID: 6693136
Filing Date: 2004-02-17
Classification: C07C

Abstract:
A compound of formula (I) or a pharmaceutically acceptable salt, ester, amide, or prodrug thereof, whereinA1 and A2 are independently selected from the group consisting of hydrogen and â€ƒprovided that one of A1 and A2 is hydrogen; L1 and L2 are independently selected from the group consisting of N(R11) and S(O)2, provided that when L1 is N(R11) then L2 is S(O)2 or when L1 is S(O)2 then L2 is N(R11); L3 is selected from the group consisting of S, S(O), S(O)2, C(O), CH(OR12), C(&boxH;NOR13), C(&boxH;NNR12R14), C(&boxH;CHC(O)OR12), CH2, and CH2CH2; L4 is selected from the group consisting of a covalent bond, C(O), CH(OR12), C(&boxH;NOR13), and C(&boxH;NNR12R14); L5 and L6 are independently selected from the group consisting of N(R15) and S(O)2, provided that when L5 is N(R15) then L6 is S(O)2 or when L5 is S(O)2 then L6 is N(R15); R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are independently selected from the group consisting of hydrogen, alkenyl, alkoxy, alkoxycarbonyl, alkyl, alkylcarbonyl, alkylcarbonyloxy, halogen, haloalkoxy, haloalkyl, hydroxy, and â€”NZ1Z2 wherein Z1 and Z2 are independently selected from the group consisting of hydrogen, alkyl, and alkylcarbonyl; R11, R12, R14, and R15 are independently selected from the group consisting of hydrogen and alkyl; and R13 is selected from the group consisting of hydrogen, alkyl, and carboxyalkyl.