Patent ID: 8065015
Filing Date: 2011-11-22
Classification: A61N,C12N

Abstract:
1. A device for the treatment of injured or diseased tissue comprising a signal source that generates a signal for application to a field generating device connected to the signal source so as to receive said signal and that is operatively disposed with respect to the injured or diseased tissue, said field generating device upon receipt of said signal causing the generation of an electric field having an amplitude of about 2-40 mV/cm in the injured or diseased tissue that is specific and selective for gene expression of at least one gene of the injured or diseased tissue, said signal source controlling and varying duration of time of application of said signal per 24 hour period and controlling and varying the duty cycle of said signal applied to said field generating device so as to optimize the selective regulation of the gene expression of said at least one gene in the injured or diseased tissue as a result of application of the specific and selective electric field.