Patent ID: 6020209
Filing Date: 2000-02-01
Classification: G01N,Y10S

Abstract:
A flow-through immunosensor for performing a displacement assay, comprising:one or more microcapillary passages having an inner diameter of less than about 1 mm, each of said one or more microcapillary passages having an antibody immobilized on its inner wall, and a labeled analog of an antigen immunologically bound to, and saturating antigen-binding sites of, said immobilized antibody, thus forming an antigen/labeled antibody pair bound to said inner wall of said microcapillary passage;a sample introduction port at which a liquid sample suspected of containing said antigen may be introduced into said one or more microcapillary passages;a detector downstream from said sample introduction port and joined to said one or more microcapillary passages, said detector detecting said labeled analog displaced from said antibody;wherein, if said imnmunosensor comprises more than one microcapillary passages, each of said microcapillary passages has bound to its inner wall an antigen/labeled antibody pair different from that bound to that of any other of said microcapillary passages.