Patent ID: 7166733
Filing Date: 2007-01-23
Classification: A61K,A61P,C07F

Abstract:
1. An amidomalonate N,O—Pt complex having the chemical structure: wherein: X is C═O or SO R q is 0 or 1; r is 2–500; [Linker] is selected from the group consisting of an alkyl group, an amino acid, a polyaminoacid, a polyethyleneglycol (PEG) and any combination of thereof; R R R the complex is obtained essentially pure by a process comprising contacting a corresponding amidomalonate O,O′—Pt complex or a mixture of amidomalonate O,O′—Pt and N,O—Pt complexes with an aqueous solution having a pH of 6.0 to 10.0.