Patent ID: 6084062
Filing Date: 2000-07-04
Classification: C07K,C12N,C12Y,C40B,G01N

Abstract:
An isolated polypeptide comprising an amino acid sequence:Arg-X.sub.1 -Cys-X.sub.2 -X.sub.3 -X.sub.4 -X.sub.5 -X.sub.6 -X.sub.7 -Cys-X.sub.8 (SEQ ID NO:43), whereinX.sub.1 is Trp or Leu;X.sub.2 is Pro, Ser, Thr or Ile;X.sub.3 is Arg, Lys or Thr;X.sub.4 is Ser, Tyr, Thr or Ala;X.sub.5 is Ser, Tyr, Asp, Val, Pro, Ala, His, Asn or Thr;X.sub.6 is Leu, Met, Gln, Arg or Lys;X.sub.7 is Glu, Gly or Arg; andX.sub.8 is Lys, Met, Ala, Val, Leu, Ile, Phe, Pro or Trp,and wherein said polypeptide binds tPA at pH 7.