Patent ID: 8865424
Filing Date: 2014-10-21
Classification: C07K,G01N

Abstract:
1. A detection reagent for the measurement of Fibrin Degradation Product (FDP) comprising: a first carrier having a first monoclonal antibody or an antigen binding fragment thereof, wherein the first monoclonal antibody or antigen binding fragment thereof does not bind a fragment E primary fibrinolysis product of FDP but binds to fibrinogen, a fragment X primary fibrinolysis product of FDP, a fragment Y primary fibrinolysis product of FDP, a fragment D primary fibrinolysis product of FDP, a fragment DD secondary fibrinolysis product of FDP, a fragment DD/E secondary fibrinolysis product of FDP, and to a fragment XDP secondary fibrinolysis product of FDP; a second carrier having a second monoclonal antibody or an antigen binding fragment thereof, wherein the second monoclonal antibody is produced by the hybridoma having accession number NITE BP-950; and a third carrier having a third monoclonal antibody or an antigen binding fragment thereof, wherein the third monoclonal antibody or fragment thereof does not bind the fibrinogen, the fragment X primary fibrinolysis product of FDP, or a fragment D primary fibrinolysis product of FDP, but binds to a fragment Y primary fibrinolysis product of FDP, the fragment E primary fibrinolysis product of FDP, the fragment DD secondary fibrinolysis product of FDP, the fragment DD/E secondary fibrinolysis product of FDP, and to a XDP secondary fibrinolysis product of FDP.