Patent ID: 8501242
Filing Date: 2013-08-06
Classification: A61K,A61P

Abstract:
1. A method of treating colon cancer in a subject, said method comprising administering to said subject an effective amount of a compound selected from the group consisting of (3,5-diiodo-4-oxo-1(4H)-pyridinyl)acetic acid, P-(diethylsulfamoyl)benzoic acid, 3-(acetylamino)-2,4,6-triiodobenzoic acid, 6-(methylamino)hexane-1,2,3,4,5-pentol, 2-acetamido-3-sulfanylpropanoic acid, Piperazine 2,3-dihydroxysuccinate, 1-ethyl-4-oxo-1,4-dihydro[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid, 2,3-dihydroxypropyl dihydrogen phosphate, and 2,3-dimercaptosuccinic acid (“NSC16867”); or a pharmaceutically acceptable salt thereof, wherein said compound is capable of interfering with or modulating association among thymidylate synthase monomers.