Patent ID: 6399613
Filing Date: 2002-06-04
Classification: A61P,C07D

Abstract:
A pharmaceutical composition comprising at least one compound of formula: in whichR represents a nitrogen atom, R1 and R3 each represent the same radical selected from the group consisting of â€”COâ€”NR5R6, â€”COâ€”N(CH(CH2OH)2)2, â€”COâ€”N(CH2OH)2, â€”COâ€”N(CH2â€”CH(CH2OH)2)2, â€”COâ€”N(CH2â€”(CHOH)nâ€”CH2OH)2 in which n is equal to 0, 1, 2, 3 or 4, â€”CH2â€”Oâ€”R6, â€”NR5â€”COâ€”R6, â€”CH2â€”NR5R6, â€”CH2â€”N(CH2OH)2, â€”CH2â€”N(CH2â€”(CHOH)yâ€”CH2OH)2 in which y is equal to 0, 1, 2, 3 or 4, â€”CH2â€”N(CH(CH2OH)2)2 and â€”CH2â€”N(CH2â€”CH(CH2OH)2)2 and R2 and R4 each represent a hydrogen atom, R5 represents a hydrogen atom or an alkyl radical, R6 represents a radical â€”CH2â€”(CHOH)mâ€”CH2OH in which m is equal to 0, 1, 2, 3 or 4, -alk-O-alk-CH2OH, -alk-O-alk, â€”CH(CH2OH)2, â€”C(CH2OH)3, â€”C(CH3)(CH2OH)2, â€”CH2â€”CH(CH2OH)2 or â€”CH(CH2OH)â€”(CHOH)xâ€”CH2OH in which x is equal to 1, 2, 3 or 4, alk represents an alkyl radical, the alkyl radicals containing, unless otherwise stated, 1 to 6 carbon atoms in a straight or branched chain, stereoisomers thereof and salts thereof with an inorganic or organic acid.