Patent ID: 6764678
Filing Date: 2004-07-20
Classification: A61K,A61P,Y10S

Abstract:
A method of providing local anesthesia to a mammal, comprising:(a) administering to said mammal in need thereof an anesthetic agent and an alpha adrenergic receptor agonist to the site to be anesthetized, wherein said anesthetic agent is administered in an amount effective to provide local anesthesia and said alpha adrenergic receptor agonist is administered in an amount effective to constrict the blood vessels at the site and prolong the local anesthesia, and then (b) administering a unit dose of a composition to said site, said unit dose comprising between about 0.00 18 mg and about 0.45 mg phentolamine mesylate or a molar equivalent of another alpha adrenergic receptor antagonist and a pharmaceutically acceptable carrier.