Patent ID: 6262095
Filing Date: 2001-07-17
Classification: A61K,A61P,C07C,C07D

Abstract:
A method for the treatment of illness associated with an alteration in venous function and/or inflammatory edems which comprises administering a sufficient amount of a tricyclic derivative or a pharmaceutically-acceptable salt thereof having the general formula: ##STR5##in which:A is either a sulfur or an oxygen atom or an R.sub.3 N radical where R.sub.3 is a hydrogen atom, a C.sub.1 -C.sub.5 alkyl radical, a substituted or unsubstituted aromatic ring, or a substituted or unsubstituted heteroaromatic ring;R.sub.1 is either a C.sub.1 -C.sub.5 alkyl radical,or an R.sub.a NH radical where R.sub.4 is a hydrogen atom, a C.sub.1 -C.sub.5 alkyl radical, a substituted or unsubstituted aromatic ring, or a substituted or unsubstituted heteroaromatic ring,an aromatic ring that may or may not be substituted by one or more acceptor or donor groups, or a heteroaromatic ring having one or more heteroatoms, which may or may not be substituted by acceptor or donor groups;R.sub.2 is a hydrogen atom, halogen atom, a C.sub.1 -C.sub.5 alkyl radical, an oxygen atom that may or may not be substituted by a C.sub.1 -C.sub.5 alkyl radical, or an NR.sub.5 R.sub.5' radical where R.sub.5 and R.sub.R' are, independently of each other, a hydrogen atom, an oxygen atom or monovalent C.sub.1 -C.sub.5 organic radical, for treatment of illness connected with an alteration in venous function and/or inflammatory edema.