Patent ID: 8252284
Filing Date: 2012-08-28
Classification: A61P,C07K,G01N,Y10S

Abstract:
1. An isolated antibody or an antigen binding fragment thereof comprising a variable light chain region comprising CDRL1, CDRL2, and CDRL3 and a variable heavy chain region comprising CDRH1, CDRH2, and CDRH3, wherein CDRL1 consists of SEQ ID NO:5, CDRL2 consists of SEQ ID NO:8, CDRL3 consists of SEQ ID NO:71, CDRH1 consists of SEQ ID NO:16, CDRH2 consists of SEQ ID NO:20, and CDRH3 consists of SEQ ID NO:26; and wherein the antibody or antigen binding fragment further comprises a constant light chain region and a constant heavy chain region.