Patent ID: 6685885
Filing Date: 2004-02-03
Classification: G01N,Y10T

Abstract:
A device for identifying analytes in a biological sample, including: a substrate having a plurality of pits, each of the pits extending into the substrate from a land area to a bottom wall having a receptor coating thereon for binding analytes upon application of the biological sample to the substrate;a laser including a beam that is sequentially directed into each of the plurality of pits; wherein when an analyte is not bound to a receptor coating of a pit, a portion of the beam reflected off the coating is combined with a portion of the beam reflected off the land area to produce a first diffraction signal, and when an analyte is bound to the coating, a portion of the beam reflected off the bound analyte is combined with a portion of the beam reflected off the land area to produce a second diffraction signal, thereby indicating the presence of the analyte.