Patent ID: 6284775
Filing Date: 2001-09-04
Classification: C07D

Abstract:
A compound of the formula ##STR23##where n is 0, 1 or 2; A is selected from the group consisting of ##STR24##where X in each occurrence is independently hydrogen, halogen, loweralkyl, hydroxy, nitro, loweralkoxy, amino, cyano, trifluoromethyl, or methylthio; Y in each occurrence is independently hydrogen, halogen, loweralkyl, hydroxy, nitro, loweralkoxy, amino, cyano, trifluoromethyl or methylthio; m is 1 or 2; k is 1 or 2; R.sub.1 and R.sub.2 independently hydrogen, lower alkyl, ##STR25##or aryl except that when R.sub.1 is ##STR26##or aryl, R.sub.2 is hydrogen or alternatively R.sub.1 +R.sub.2 taken together with the carbon atom to which they are attached from a cyclopentane, cyclohexane, cycloheptane, pyran, thipyran, indan or piperidine ring; R.sub.3 and R.sub.4 are independently hydrogen or loweralkyl, or alternatively R.sub.3 +R.sub.4 taken together with the carbon atom to which they are attached from a cyclopentane, cyclohexane, cycloheptane, pyran, thipyran, pyrrolidine or piperidine ring, the term signifying an unsubstituted phenyl group or a phenyl group substituted with 1, 2 or 3 substituents each of which being independently loweralkyl, loweralkoxy, hydroxy, halogen, loweralkylthio, cyano, amino or trifluoromethyl, or a phamaceutically acceptable acid addition salt thereof.