Patent ID: 6127376
Filing Date: 2000-10-03
Classification: A61P,C07D

Abstract:
A compound selected from the group consisting of the following formulae: ##STR12## wherein: Z.sup.1 is --O--;Z.sup.2 is --O--;R.sup.1 is --OR.sup.7 ;R.sup.2 is --C(NH)NH.sub.2 ;R.sup.3 is (1,2)-imidazolyl (optionally substituted by methyl) or (1,2)-imidazolinyl (optionally substituted by methyl);R.sup.4 is hydrogen;R.sup.5 is hydrogen; andR.sup.6 is aryl (optionally substituted by halo, haloalkyl, alkyl, aryl, aralkyl, hydroxy, alkoxy, aralkoxy, amino, dialkylamino, monoalkylamino, nitro, carboxy, alkoxycarbonyl, aminocarbonyl, monoalkylaminocarbonyl, or dialkylaminocarbonyl); andR.sup.7 is hydrogen or alkyl;as a single stereoisomer or a mixture thereof; or a pharmaceutically acceptable salt thereof.