Patent ID: 6066722
Filing Date: 2000-05-23
Classification: A61P,C07D,C07H

Abstract:
A compound having the formula: ##STR25## wherein A is CH or N; X and Y are independently selected from H, OH or halogen except that when one of X and Y is hydroxy or halogen, the other is hydrogen; and Z is OH or, when X is hydroxy, Z is selected from hydrogen, halogen, hydroxy, SQ or OQ where Q is an optionally substituted alkyl, aralkyl or aryl group; E is chosen from CO.sub.2 H or a corresponding salt form, CO.sub.2 R, CN, CONH.sub.2, CONHR or CONR.sub.2 ; and G is chosen from NH.sub.2, NHCOR, NHCONHR or NHCSNHR; or a tautomer thereof; or a pharmaceutically acceptable salt thereof; or an ester thereof; or a prodrug thereof.