Patent ID: 8309587
Filing Date: 2012-11-13
Classification: A61P,C07D

Abstract:
1. A compound of formula I: or a pharmaceutically acceptable salt thereof; wherein: ring Z is a 5-6 membered unsaturated or aromatic ring having 1-4 ring heteroatoms selected from O, S, or N, wherein Z is optionally substituted with up to q occurrences of R W and Y x and y each is 2; w is 0-4; v is 0 or 1; z is 0-4; V and X each is a bond, O, NR Q is a bond or a C1-C6 straight or branched alkylidene chain, wherein up to two non-adjacent methylene units of Q are optionally and independently replaced by —CO—, —CS—, —COCO—, —CONR R R R R n is 0, 1 or 2; Y is halo, CN, NO R R R R R R Z′ is selected from halo, CN, NO R