Patent ID: 7459471
Filing Date: 2008-12-02
Classification: A61P,C07F

Abstract:
1. An inclusion compound having a cucurbituril derivative of the formula 1 as a host molecule and a metal complex of the formula 2 as a guest molecule: wherein R 1 and R 2 are independently selected from the group consisting of H, C 1 -C 30 alkyl, C 1 -C 30 alkene, C 1 -C 30 alkyne, C 1 -C 30 alkylthio, C 1 -C 30 alkylcarboxy, C 1 -C 30 alkylhydroxy, C 1 -C 30 alkylsilyl, C 1 -C 30 alkyloxy, C 1 -C 30 haloalkyl, nitro, C 1 -C 30 alkylamine, amine, C 5 -C 30 unsubstituted cycloalkyl or C 5 -C 30 cycloalkyl having a hetero atom, and C 6 -C 15 unsubstituted aryl or C 6 -C 15 aryl having a hetero atom, n is an integer from 4 to 20, M is a divalent or quartemary metal ion selected from the group consisting of transition metals, lanthanide metals, actinide metals, alkali metals and alkali earth metals, X 1 and X 2 meet one selected from the following conditions (i) and (ii): (i) X 1 and X 2 are independently selected from the group consisting of halogen atom, C 1 -C 30 haloalkyl, hydroxy, C 1 -C 30 alkylcarboxy, and C 1 -C 30 alkyldicarboxy; or (ii) X 1 and X 2 are interconnected to each other and are one among components represented by the structural formulas (a) through (h): X 3 and X 4 meet one selected from the following conditions (i) and (ii): (i) when M is a divalent metal ion, X 3 and X 4 denote non-bonding; or (ii) when M is a quaternary metal ion, X 3 and X 4 are independently selected from the group consisting of halogen atom, C 1 -C 30 haloalkyl, hydroxy, C 1 -C 30 alkylcarboxy, and C 1 -C 30 alkyldicarboxy, R 3 , R 4 , R 5 , R 6 , R 7 and R 8 meet one selected from the following conditions (i), (ii) and (iii): (i) R 3 , R 4 , R 5 , R 6 , R 7 and R 8 are independently selected from the group consisting of H, C 1 -C 30 alkyl, C 1 -C 30 alkene, C 1 -C 30 alkyne, C 1 -C 30 alkylthio, C 1 -C 30 alkylcarboxy, C 1 -C 30 alkylhydroxy, C 1 -C 30 alkylsilyl, C 1 -C 30 alkyloxy, C 1 -C 30 haloalkyl, nitro, C 1 -C 30 alkylamine, amine, C 6 -C 30 unsubstituted cycloalkyl or C 5 -C 30 cycloalkyl having a hetero atom, and C 6 -C 15 unsubstituted aryl or C 6 -C 15 aryl having a hetero atom; (ii) R 3 , R 4 , R 7 and R 8 are independently selected from the group consisting of H, C 1 -C 30 alkyl, C 1 -C 30 alkene, C 1 -C 30 alkyne, C 1 -C 30 alkylthio, C 1 -C 30 alkylcarboxy, C 1 -C 30 alkylhydroxy, C 1 -C 30 alkylsilyl, C 1 -C 30 alkyloxy, C 1 -C 30 haloalkyl, nitro, C 1 -C 30 alkylamine, amine, C 6 -C 30 unsubstituted cycloalkyl or C 5 -C 30 cycloalkyl having a hetero atom, and C 6 -C 15 unsubstituted aryl or C 6 -C 15 aryl having a hetero atom, and R 5 and R 6 are interconnected to each other and one among components represented by the structural formulas (i) through (q): and (iii) R 3 , R 4 and R 8 are independently selected from the group consisting of H, C 1 -C 30 alkyl, C 1 -C 30 alkene, C 1 -C 30 alkyne, C 1 -C 30 alkylthio, C 1 -C 30 alkylcarboxy, C 1 -C 30 alkylhydroxy, C 1 -C 30 alkylsilyl, C 1 -C 30 alkyloxy, C 1 -C 30 haloalkyl, nitro, C 1 -C 30 alkylamine, amine, C 6 -C 30 unsubstituted cycloalkyl or C 5 -C 30 cycloalkyl having a hetero atom, and C 6 -C 15 unsubstituted aryl or C 6 -C 15 aryl having a hetero atom, and R 5 and R 6 , and R 6 and R 7 are interconnected to each other and represented by the structural formula (o) wherein asterisk denotes a position bonded with N: