Patent ID: 9040286
Filing Date: 2015-05-26
Classification: A61K,A61P,C07K,C12N,C12Q,C12Y,G01N

Abstract:
1. A method for facilitating the diagnosis of lung cancer or melanoma in a subject, the method comprising: selecting a subject having at least one solid tumor or growth or a nevus; measuring the level of SETDB1 in a biological sample obtained from the subject who has at least one solid tumor or growth or a nevus, identifying the likelihood of cancer in the subject by comparing the measured level of SETDB1 to a reference level, determining whether the subject has cancer and therefore requiring cancer treatment or whether the subject has a benign growth based upon the comparison wherein an increase of at least 10% in the SETDB1 level in the biological sample compared to the reference level is indicative of cancer in the subject.