Patent ID: 8389527
Filing Date: 2013-03-05
Classification: A61P,C07D

Abstract:
1. A compound according to formula I: or a pharmaceutically acceptable salt thereof, wherein R R R R R R R R provided that if R  R  R  then R wherein: said heterocyclo is a fully saturated or unsaturated, aromatic or nonaromatic cyclic group, which is a 4 to 7 membered monocyclic, 7 to 11 membered bicyclic, or 10 to 15 membered tricyclic ring system, which has at least one heteroatom selected from nitrogen, oxygen, and sulfur in at least one carbon atom-containing ring; said heterocyclo may be attached at any heteroatom or carbon atom; said heteroaryl is a 4 to 7 membered monocyclic, 7 to 11 membered bicyclic, or 10 to 15 membered tricyclic aromatic ring system, which has at least one heteroatom selected from nitrogen, oxygen, and sulfur and at least one carbon atom-containing ring; and said heterocyclo and heteroaryl are substituted with one to four substituents selected from alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, arylalkyl, arylalkyloxy, halo, haloalkyl, hydroxy, alkoxy, oxo, alkanoyl, aryloxy, alkanoyloxy, amino, alkylamino, arylamino, arylalkylamino, disubstituted amines in which the 2 amino substituents are selected from alkyl, aryl or arylalkyl; alkanoylamino, aroylamino, aralkanoylamino, substituted alkanoylamino, substituted arylamino, substituted aralkanoylamino, thiol, alkylthio, arylthio, arylalkylthio, alkylthiono, arylthiono, arylalkylthiono, alkylsulfonyl, arylsulfonyl, arylalkylsulfonyl, sulfonamido, substituted sulfonamido, ureido, nitro, cyano, carboxy, carboxyalkyl, carbamyl, substituted carbamyl, alkoxycarbonyl, aryl, substituted aryl, guanidino, and heterocyclyl, and substituted heterocyclyl.