Patent ID: 8475812
Filing Date: 2013-07-02
Classification: A61K,A61L,A61P

Abstract:
1. A method for manufacturing an improved cross-linked gelatin sponge comprising a protein or peptide active ingredient comprising the steps of: a) providing a cross-linked gelatin sponge having at least one surface; b) homogenously applying an aqueous liquid comprising a protein or peptide active ingredient to said at least one surface of said sponge, wherein the volume of the liquid intake into said surface of said sponge is equal to or less than 5% of the volume of the sponge in a); and c) drying the sponge by a drying step selected from the group consisting of thermal drying, vacuum drying and freeze drying, thereby obtaining a flexible, dry cross linked gelatin sponge comprising a stable layer of protein or peptide active ingredient on at least one surface of the sponge.