Patent ID: 6352862
Filing Date: 2002-03-05
Classification: G01N,Y10S

Abstract:
An analytical test device suitable for analyzing a liquid sample suspected of containing an analyte, said device comprising the following separate components in sequential fluid communication: (1) a liquid sample application member; (2) a macroporous body positioned to receive liquid sample from said sample application member, said macroporous body including a mobilizable labeled specific binding reagent for binding to analyte in said sample; and (3) a dry porous carrier strip downstream of said macroporous body, said carrier strip including a detection zone comprising an unlabeled immobilized specific binding reagent for binding to said analyte, said mobilizable labeled reagent being freely soluble or dispersible in liquid sample applied to the liquid application member and free to move therewith through the pores of said macroporous body whereby it is transported by said liquid sample from said macroporous body to said detection zone, said macroporous body and carrier strip comprising separate and different materials which overlap at their adjacent ends to provide effective contact between these components to ensure that liquid sample applied to said application member can permeate sequentially through the macroporous body and the carrier strip.