Patent ID: 8119821
Filing Date: 2012-02-21
Classification: A23L,C07D

Abstract:
1. A process of preparing a compound having structural Formula (a): comprising: mixing a compound having structural Formula (b): with a compound having structural Formula (c): in the presence of an organic amine at a temperature of about 0° C. or below to obtain a reaction mixture; maintaining the reaction mixture at a temperature of about 0° C. or below for about 30 to about 90 minutes; concentrating the reaction mixture to obtain a slurry; and filtering the slurry to obtain the compound having structural Formula (a) as solid particles; wherein: R R or alternatively, R 1 and R 2 , together with the atoms to which they are attached, form a carbocyclic ring or heterocyclic ring; X is CN or —C(O)R R each R