Patent ID: 7351853
Filing Date: 2008-04-01
Classification: A61K,C07C

Abstract:
1. A method for using a controlled exothermic granulation reaction to form mineral granules, the method comprising: introducing a solvent into a reaction vessel; dissolving at least one edible acid into the solvent to form an edible acid solution in the reaction vessel; introducing a first portion of a total amount of a mineral base into the reaction vessel to form a first mixture in which the first portion of the mineral base reacts exothermically with a first portion of the edible acid solution to generate heat within the reaction vessel; mixing the first mixture while at a temperature below the boiling point of the solvent; introducing a last portion of the total amount of the mineral base into the reaction vessel to form a final mixture in which the last portion of the mineral base reacts exothermically with a last portion of the edible acid solutions to generate additional heat within the reaction vessel and increase solids concentration relative to the solvent; and mixing the final mixture to form granules of a salt of the mineral base and edible acid having a desired dimension, the final mixture being mixed at a temperature so as to prevent a solid from becoming baked or burnt onto the reaction vessel.