Patent ID: 6391562
Filing Date: 2002-05-21
Classification: B01J,C07H,C40B,Y10S

Abstract:
An apparatus for analyzing samples, each labeled with a different species of fluorophore, using a two-dimensional probe array comprising:a two-dimensional probe array of a plurality of small spherical particles having different probes, respectively, fixed thereon, said probes being capable of hybridizing to different samples to be analyzed, respectively, said small spherical particles having different diameters, the species of said probes being distinguished, respectively, by the diameters of said small spherical particles, and said small spherical particles being arrayed two-dimensionally on a transparent plate; a first light sources which emits a light for irradiating said two-dimensional probe array; a second light source which emits exciting light for irradiating said two-dimensional probe array; a detector which detects the light passed through said two-dimensional probe array by irradiating said two-dimensional probe array with the light from said first light source and detects fluorescence emitted from the fluorophore labeling each of said samples by irradiating said two-dimensional probe array with exciting light; and a data processing unit which obtains the fluorescence emitted from said fluorophore labeling each of said samples captured by said probes, measures the diameters of said small spherical particles based on an image formed by the light passed through said two-dimensional probe array, and recognizes the species of said probes capturing said samples, based on the measured diameters of said small spherical particles.