Patent ID: 6313339
Filing Date: 2001-11-06
Classification: A01N,C07C

Abstract:
A compound of the formula: ##STR31##whereinX is N or CH; Y is O, S or NR.sub.8 ;A is selected from the group consisting of hydrogen, halo, cyano, (C.sub.1 -C.sub.12)alkyl, and (C.sub.1 -C.sub.12)alkoxy;Z is O, N--OR.sub.9 or N--R.sub.10 ;R.sub.1 and R.sub.8 are independently selected from the group consisting of hydrogen and (C.sub.1 -C.sub.4)alkyl;R.sub.2 is selected from the group consisting of hydrogen, (C.sub.1 -C.sub.12)alkyl, halo(C.sub.1 -C.sub.12)alkyl, (C.sub.3 -C.sub.7)cycloalkyl, halo(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.2 -C.sub.8)alkenyl, halo(C.sub.2 -C.sub.8)alkenyl, (C.sub.2 -C.sub.8)alkynyl, halo(C.sub.2 -C.sub.8)alkynyl, cyano, (C.sub.1 -C.sub.4)alkoxycarbonyl, aryl, aralkyl, heterocyclic, and heterocyclic(C.sub.1 -C.sub.4)alkyl;R.sub.3 and R.sub.7 are each independently selected from the group consisting of hydrogen, (C.sub.1 -C.sub.12)alkyl, halo(C.sub.1 -C.sub.12)alkyl, (C.sub.2 -C.sub.8)alkenyl, halo(C.sub.2 -C.sub.8)alkenyl, (C.sub.2 -C.sub.8)alkynyl, halo(C.sub.2 -C.sub.8)alkynyl, aryl, aralkyl, heterocyclic and heterocyclic(C.sub.1 -C.sub.4)alkyl, provided that at least one of R.sub.3 and R.sub.7 is aryl, aralkyl, heterocyclic, or heterocyclic(C.sub.1 -C.sub.4)alkyl;R.sub.4, R.sub.5 and R.sub.6 are each independently selected from the group consisting of hydrogen, (C.sub.1 -C.sub.12)alkyl, halo(C.sub.1 -C.sub.12)alkyl, (C.sub.3 -C.sub.7)cycloalkyl, halo(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.2 -C.sub.8)alkenyl, halo(C.sub.2 -C.sub.8)alkenyl, (C.sub.2 -C.sub.8)alkynyl, halo(C.sub.2 -C.sub.8)alkynyl, halo, cyano, (C.sub.1 -C.sub.4)alkoxycarbonyl, aryl, aralkyl, heterocyclic and heterocyclic(C.sub.1 -C.sub.4)alkyl;R.sub.9 is selected from the group consisting of hydrogen, (C.sub.1 -C.sub.12)alkyl, halo(C.sub.1 -C.sub.12)alkyl, (C.sub.3 -C.sub.7)cycloalkyl, halo(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.2 -C.sub.8)alkenyl, halo(C.sub.2 -C.sub.8)alkenyl, (C.sub.2 -C.sub.8)alkynyl, halo(C.sub.2 -C.sub.8)alkynyl, (C.sub.1 -C.sub.4)alkylcarbonyl, arylcarbonyl, aralkylcarbonyl, heterocyclic carbonyl, (C.sub.1 -C.sub.4)alkoxycarbonyl, aryl, aralkyl, heterocyclic and heterocyclic(C.sub.1 -C.sub.4)alkyl;R.sub.10 is selected from the group consisting of hydrogen, (C.sub.1 -C.sub.12)alkyl, halo(C.sub.1 -C.sub.12)alkyl, (C.sub.2 -C.sub.8)alkenyl, halo(C.sub.2 -C.sub.8)alkenyl, (C.sub.2 -C.sub.8)alkynyl, halo(C.sub.2 -C.sub.8)alkynyl, aryl, aralkyl, heterocyclic or heterocyclic(C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkylcarbonyl, and (C.sub.1 -C.sub.4)alkoxycarbonyl, arylcarbonyl, aralkylcarbonyl, heterocyclic carbonyl, (C.sub.1 -C.sub.4)alkylaminocarbonyl, arylaminocarbonyl, N--R.sub.8 R.sub.9, N.dbd.CR.sub.11 R.sub.12, (C.sub.1 -C.sub.4)alkylsulfonyl, N=cyclopropyl, N=cyclobutyl, N=cyclopentyl, N=cyclohexyl, N=benzyl, and arylsulfonyl;R.sub.11 and R.sub.12 are each independently selected from the group consisting of hydrogen, (C.sub.1 -C.sub.12)alkyl, halo(C.sub.1 -C.sub.12)alkyl, (C.sub.1 -C.sub.12)alkoxy, halo(C.sub.1 -C.sub.12)alkoxy, (C.sub.3 -C.sub.7)cycloalkyl, halo(C.sub.3 -C.sub.7)cycloalkyl, (C.sub.2 -C.sub.8)alkenyl, halo(C.sub.2 -C.sub.8)alkenyl, (C.sub.2 -C.sub.8)alkynyl, halo(C.sub.2 -C.sub.8)alkynyl, cyano, (C.sub.1 -C.sub.4)alkoxycarbonyl, (C.sub.1 -C.sub.4)alkylamino, aryl, aralkyl, heterocyclic, and heterocyclic(C.sub.1 -C.sub.4)alkyl.