Patent ID: 6582950
Filing Date: 2003-06-24
Classification: A61K,C07K

Abstract:
An isolated nucleic acid fragment that hybridizes to at least a portion of at least one of the nucleic acid fragments represented by SEQ ID NO:6 or SEQ ID NO:4 or their complementary strands under hybridization conditions of prehybridization for 1 hour at 62Â° C. in hybridization solution (5Ã—SSC (1Ã—SSC is 0.15 M NaCL, 0.015 M sodium citrate), 0.02% sodium dodecyl sulfate (SDS), 0.1% N-lauroylsarcosine, 1% Blocking Reagent) followed by two stringency washes with 2Ã—SSC, 0.1% SDS for 5 minutes at room temperature and once with 0.5Ã—SSC, 0.1% SDS for 15 minutes at 62Â° C., said isolated nucleic acid fragment encodes a polypeptide that binds human complement C3 protein.