Patent ID: 7915304
Filing Date: 2011-03-29
Classification: A61K,A61P,C07D,Y10S

Abstract:
1. A method of treating diabetic retinopathy, comprising administering, to a subject in need thereof, a therapeutically effective amount of at least one compound selected from the group consisting of: 1-(3-chlorophenyl)-3-(4-fluorophenyl)-pyrrole-2,5-dione; 1-(3-chlorophenyl)-3-(3-fluorophenyl)-pyrrole-2,5-dione; 1-(3-chloro-4-fluorophenyl)-3-(3-fluorophenyl)-pyrrole-2,5-dione; 1-(3-chlorophenyl)-3-(2-fluorophenyl)-pyrrole-2,5-dione; 1-(3-chloro-4-fluorophenyl)-3-(2-fluorophenyl)-pyrrole-2,5-dione; 1-(3-bromophenyl)-3-phenyl-pyrrole-2,5-dione; 1-(3-methylphenyl)-3-phenyl -pyrrole-2,5-dione; 1-(3-trifluoromethylphenyl)-3-phenyl-pyrrole-2,5-dione; 1-(3-chlorophenyl)-3-(4-hydroxyphenyl)-pyrrole-2,5-dione; 1-(3-chlorophenyl)-3-(4-methoxyphenyl)-pyrrole-2,5-dione; 1-(3-methylphenyl)-3-(4-chlorophenyl)-pyrrole-2,5-dione; 1-(3-chlorophenyl)-3-(4-chlorophenyl)-pyrrole-2,5-dione; 1-(3-chlorophenyl)-3-(4-methylphenyl)-pyrrole-2,5-dione; 1-(5-chloro-2-methoxyphenyl)-3-phenyl-pyrrole-2,5-dione; 1-(3-chloro-4-fluorophenyl)-3-phenyl-pyrrole-2,5-dione; and 1-(3-chlorophenyl)-3-phenyl-pyrrole-2,5-dione.