Patent ID: 6057435
Filing Date: 2000-05-02
Classification: A61K,A61P,C07K,G01N,Y10S

Abstract:
An isolated nucleic acid molecule hybridizing to the complement of the nucleic acid of SEQ ID NO: 1 under the following conditions: incubation in a mixture of 5 .times.SSPE, 2.times.Denhardt's solution, 100 mg/ml denatured sheared salmon sperm DNA, 50% formamide, and 2% SDS at 42.degree. C., followed by washed in a mixture of 2.times.SSC, and 0.05% SDS at room temperature and 0.1.times.SSC and 0.1% SDS at 50.degree. C., wherein said nucleic acid molecule encodes a polypeptide that binds to a native TIE receptor.