Patent ID: 8242238
Filing Date: 2012-08-14
Classification: A61K,A61P,C07K,C12N

Abstract:
1. An isolated or purified oligopeptide or polypeptide comprising an amino acid sequence with at least 94% identity to SEQ ID NO:13 in which: (i) from 0 to 4 amino acids are substituted, deleted, or inserted as compared with SEQ ID NO:13, and (ii) at least one of the five amino acid substitutions in the S antigen of the hepatitis B variant HDB 05 as compared to the HBV adw wild type is preserved, wherein said substitutions are chosen from T 115 (R), P 120 (Q), S 154 (L), E 164 (V), and Q 181 (R) of the S antigen of HBV.