Patent ID: 8962010
Filing Date: 2015-02-24
Classification: A61K,A61P,C07K,C12N

Abstract:
1. An intravaginal drug delivery device comprising: (a) a device body comprising a hydrophobic carrier material having at least one channel defining at least one opening to an exterior of said device body, said at least one channel being adapted to receive at least one drug-containing insert; and (b) at least one drug-containing insert positioned in said at least one channel, said drug-containing insert being capable of releasing a pharmaceutically effective amount of at least one drug suitable for intravaginal administration and containing at least one water-soluble release enhancer in an amount ranging from about 20% to about 70% by weight of said at least one drug-containing insert, said at least one drug and said at least one water-soluble release enhancer being dispersed in an insert carrier material; wherein said hydrophobic carrier material and said insert carrier material may be the same or different; wherein said at least one drug-containing insert is exposed on said exterior of said device body when said intravaginal drug delivery device is in use; wherein said at least one drug-containing insert is arranged to maintain surface contact between said insert and said channel in use and to be removable from said device body; wherein said at least one drug-containing insert defines a right circular cylinder, extends substantially perpendicular to the main plane of the device body, and has a cross-sectional diameter of from about 0.5 mm to about 8 mm; and wherein the device body is a partial or complete toroid shape.