Patent ID: 6399834
Filing Date: 2002-06-04
Classification: C07C,Y02P

Abstract:
A method for producing chiral aldehydes comprising enantioselective hydroformylation of prochiral substrates with the aid of a catalyst consisting of a transition metal and a chiral ligand, wherein said hydroformylation is performed in compressed carbon dioxide as a reaction medium at temperatures of âˆ’20Â° C.0total<500 bar, and said chiral ligand is a compound of general formula 1 wherein the rings R7-R10 drawn with dotted lines are optional and one or more of rings R1-R6 or R7-R10 are substituted with one or more independently selected substituents of general formula â€”(CH2)x(CF2)yF(x=0-5; y=1-12) or their branched isomers.