Patent ID: 8298577
Filing Date: 2012-10-30
Classification: A61K,A61P

Abstract:
1. A dosage form comprising: about 20 to about 200,000 micrograms of an oxycodone, about 15 to about 60% of an effervescent material, wherein said effervescent material comprises an acid source and a source of a reactive base; about 0.5 to about 25% w/w of a pH adjusting substance, wherein said pH adjusting substance is different from the acid source and the reactive base in the effervescent material, a filler, wherein said filler is mannitol; and a starch glycolate, wherein said dosage form is configured for the delivery of said oxycodone and salts thereof across the oral mucosa as a consequence of buccal, gingival or sublingual administration.