Patent ID: 6245342
Filing Date: 2001-06-12
Classification: A61K,A61P,A61Q

Abstract:
A cosmetic preparation with a peptide additive, comprising as active ingredients a combination of the following ingredients:a) a peptide derivative of the formula (Lip)X-His-Phe-Arg-Y, whereLip represents thioctic acid or one of its derivatives,X denotes Glu, OH, or NH.sub.2Y denotes Trp-Gly-OH, Trp-Gly-NH.sub.2, Trp-NH.sub.2 orPhe denotes Homo-Phe or P-fluoro-Phe,and the amino acids may be present in the form D, L or DL, or mixtures thereof, in the amount of 0.05 to 2.5 mg pure peptide derivative per kg total weight, where the peptide derivative is mixed with xanthine in a ratio of 0.5 to 2 mol per 100 mol peptide;b) at least 0.5 wt % of a mixture of enzymes and vitamins containing at least 150 U/mL peroxide dismutase (POD);c) 65 to 99.5 wt % of an inert, non-toxic cosmetically acceptable carrier; andd) 0 to 12 wt % other active ingredients, where the percentage amounts are all based on the total weight of the preparation.