Patent ID: 8883766
Filing Date: 2014-11-11
Classification: A61P,C07C,C07D

Abstract:
1. A method of modulating a sodium ion channel comprising the step of contacting said sodium ion channel with a compound of formula I: or a pharmaceutically acceptable salt thereof, wherein R′ —C(O)NR A NR A —, —C(O)O—, —NR A C(O)O—, —O—, —NR A C(O)NR A —, —NR A NR A —, —S—, —SO—, —SO 2 —, —NR A —, —SO 2 NR A —, or —NR A SO 2 NR A —; R R R′ R R R —NR C C(O)O—, —O—, —NR C C(O)NR C —, —NR C NR C —, —S—, —SO—, —SO 2 —, —NR C —, —SO 2 NR C —, or —NR C SO 2 NR C —; R R R —NR D C(O)O—, —O—, —NR D C(O)NR D —, —NR D NR D —, —S—, —SO—, —SO 2 —, —NR D —, —SO 2 NR D —, or —NR D SO 2 NR D —; R R