Patent ID: 6150539
Filing Date: 2000-11-21
Classification: A61P,C07D

Abstract:
A compound having the structure I: ##STR5## where OR.sup.1 is selected from (i) a carboxylic ester, carbonate, or inorganic ester, having a central atom selected from carbon, sulfur, phosphorus, nitrogen, and boron, and having linked to said central atom at least one group of the form --Y--Z or --O--Y--Z, where Y is a branched or unbranched C.sub.1 -C.sub.6 alkyl or alkenyl chain, and Z is hydrogen or a polar group selected from keto, aldehyde, carboxylate, carboxylic ester, hydroxy, alkoxy, polyether, thiol, alkylthio, amino, cyano, nitro, sulfate, nitrate, phosphate, or a 5- to 7-membered heterocycle having ring atoms selected from carbon, nitrogen, oxygen, and sulfur, and three to six carbon ring atoms, and(ii) a mono-, di- or trisaccharide linked to C14 at an anomeric center;and OR.sup.3 is OH or O--(C.dbd.O)R, where R is lower alkyl.