Patent ID: 8252267
Filing Date: 2012-08-28
Classification: A61P,C07K,C12N

Abstract:
1. A method for detecting one or more cancer cells expressing a Dickkopf-like 1 (DKKL-1) splice product in a sample, the method comprising contacting the sample with an antibody that specifically binds the DKKL-1 splice product, does not specifically bind to wild-type DKKL-1, wherein the antibody is labeled, the label is a radioisotope selected from the group consisting of: 18 F, 43 K, 52 Fe, 57 Co, 67 Cu, 67 Ga, 77 Br, 87 MSr, 86 Y, 90 Y, 99 MTc, 111 In, 123 I, 125 I, 127 Cs, 129 Cs, 131 I, 132 I, 197 Hg, 203 Pb, 206 Bi and detecting the label in the sample.