Patent ID: 8399621
Filing Date: 2013-03-19
Classification: A61K,A61P,C07K,G01N

Abstract:
1. A monoclonal antibody or antibody fragment thereof, wherein said monoclonal antibody competes for binding to an extracellular region of CD4 with, and/or blinds to the same epitope in an extracellular regions of CD4 as, a reference antibody, wherein said reference antibody comprises a heavy chain (H chain) and a light chain (L chain), wherein complementarity determining regions (CDRs) 1 to 3 of said H chain comprise the amino acid sequences of SEQ ID NOs:51 to 53, respectively, and wherein CDRs 1 to 3 of said L chain comprise the amino acid sequences of SEQ ID NOs:54 to 56, respectively.