Patent ID: 6436914
Filing Date: 2002-08-20
Classification: C07C,C07D,C07F

Abstract:
A compound of the formula or a pharmaceutically acceptable salt thereof, or stereoisomers thereof, whereinR1 is lower alkyl, aryl or arylalkyl; A is hydrogen or B is hydrogen, alkyl, alkenyl, or but when A is hydrogen, B may only be R2, R2â€², R2â€³, R3, R3â€² and R3â€³ are independently hydrogen, hydroxy, alkoxy, difluoromethoxy, trifluoromethoxy, 2,2,2-trifluoroethoxy, aryloxy, arylalkoxy, hydroxyalkoxy, lower alkyl, trifluoromethyl, halogen, cyano, alkylthio, alkylsulfinyl, alkylsulfonyl, â€”(CH2)nNR4COR5, â€”CONR4R4â€², â€”CO2R5, â€”NR4SO2R1, â€”NR4R4â€², â€”OCH2CH2NR4R4â€², â€”OCH2CONR4R4â€², â€”OCH2CO2R4, â€”PO3R4R4â€² or aryl; or R2 and R2â€² or R3 and R3â€² may together form a carbocycle or heterocycle; m is 0âˆ’3; n=0âˆ’3; R4 and R4â€² are independently hydrogen or lower alkyl; and R5 is lower alkyl.