Patent ID: 8202984
Filing Date: 2012-06-19
Classification: A61K,A61P,C07D,C07H

Abstract:
1. A compound of formula (I): wherein: Ring A is an unsaturated monocyclic heterocyclic ring, or an unsaturated fused heterobicyclic ring, wherein when Ring A is an unsaturated fused heterobicyclic ring, the sugar moiety X-(sugar) and the moiety —Y-(Ring B) are both on the same heterocyclic ring of the unsaturated fused heterobicyclic ring and the unsaturated fused heterobicyclic ring is selected from the group consisting of indoline, isoindoline, benzothiazole, benzoxazole, indole, indazole, quinoline, isoquinoline and dihydroisoquinoline, and wherein each of the unsaturated monocyclic heterocyclic ring and the unsaturated fused heterobicyclic ring may optionally be substituted by 1-3 substituents, independently selected from the group consisting of a halogen atom, a hydroxy group, a cyano group, a nitro group, an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a cycloalkylidenemethyl group, an alkoxy group, an alkanoyl group, an alkylthio group, an alkylsulfonyl group, an alkylsulfinyl group, an amino group, a mono- or di-alkylamino group, a sulfamoyl group, a mono- or di-alkylsulfamoyl group, a carboxyl group, an alkoxycarbonyl group, a carbamoyl group, a mono- or di-alkylcarbamoyl group, an alkylsulfonylamino group, a phenyl group, a phenoxy group, a phenylsulfonylamino group, a phenylsulfonyl group, and a heterocyclyl group; Ring B is a benzene ring, which may optionally be substituted by 1-3 substituents, independently selected from the group consisting of a halogen atom, a hydroxy group, a cyano group, a nitro group, an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a cycloalkylidenemethyl group, an alkoxy group, an alkanoyl group, an alkylthio group, an alkylsulfonyl group, an alkylsulfinyl group, an amino group, a mono- or dialkylamino group, a sulfamoyl group, a mono- or di-alkylsulfamoyl group, a carboxyl group, an alkoxycarbonyl group, a carbamoyl group, a mono- or di-alkylcarbamoyl group, an alkylsulfonylamino group, a phenyl group, a phenoxy group, a phenylsulfonylamino group, a phenylsulfonyl group, a heterocyclyl group, an alkylene group and an oxo group; wherein each of the above-mentioned substituents on Ring A and Ring B may optionally be substituted by 1-3 substituents, independently selected from the group consisting of a halogen atom, a cyano group, an alkyl group, a haloalkyl group, an alkoxy group, a haloalkoxy group, an alkanoyl group, a mono- or di-alkylamino group, a carboxyl group, a hydroxy group, a phenyl group, an alkylenedioxy group, an alkyleneoxy group, and an alkoxycarbonyl group; X is a nitrogen atom; and Y is —(CH or a pharmaceutically acceptable salt thereof.