Patent ID: 7928137
Filing Date: 2011-04-19
Classification: A61K,C07C,C07D,C07K

Abstract:
1. A serine protease inhibitor compound of formula (I) where R 1 and R 2 each independently is hydrogen or hydroxyl, alkoxy, alkyl, aminoalkyl, hydroxyalkyl, alkoxyalkyl, alkoxycarbonyl, acyloxymethoxycarbonyl or alkylamino optionally substituted by hydroxy, alkylamino, alkoxy, oxo, aryl or cycloalkyl; each R X—X is —CONH—; L is an organic linker group containing 1 to 5 backbone atoms selected from C, N, O and S, or a branched alkyl or cyclic group; Y is a CR Cy is an aryl group having 5 to 10 ring atoms including 1, 2, or 3 heteroatoms selected from O, N, or S, wherein Cy is optionally substituted by groups R Lp(D)