Patent ID: 6268312
Filing Date: 2001-07-31
Classification: A01N,C07D

Abstract:
A compound of the formula (I) ##STR63##wherein R.sup.1 is pyridinyl optionally substituted with a group selected from the group consisting of lower alkyl, lower alkenyl, lower alkynyl, cycloalkyl, cyloalkenyl, lowe pikanoyl, lower alkylsilyl, halogenated lower alkyl, di (lower) alkylamino, phenyl, Phenyl (lower) alkyl, phenyl (lower) alkenyl, furyl (lower) alkyl, furyl (lower) alkenyl, halogen, nitro, cyano, lower alkylthio, OR.sup.11, wherein R.sup.11 is hydrogen, lower alkyl, lower alkenyl, lower alkynyl, Phenyl, lower alkoxyphenyl, nitrophenyl, phenyl (lower) alkyl, cyanophenyl (lower) alkyl, benzoyl, tetrahydropyranyl, pyridyl, trifluoromethylpyridyl, Pyrimidinyl, benzothiazolyl, quinolyl, benzoyl (lower) alkyl, benzosulfonyl or lower alkylbenzenesulfonyl, or --CH.sup.2 --Z--R.sup.12, wherein Z is --O--, --S--, or --NR.sup.13 -- wherein R.sup.13 is hydrogen or lower alkyl, R.sup.12 is phenyl, halophenyl, lower alkoxyphenyl, pyridyl, or pyrimidinyl; R.sup.2 is alkyl, alkenyl, alkynyl or cycloalkyl; R.sup.3 is an imidazolyl optionally substituted with a group selected form the group consisting of lower alkyl, lower alkenyl, lower alkynyl, cycloalkyl, cyloalkenyl, lower alkanoyl, lower alkylsilyl, halogenated lower alkyl, di (lower) alkylamino, phenyl, phenyl (lower) alkyl, phenyl (lower) alkenyl, furyl (lower) alkyl, furyl (lower) alkenyl, halogen, nitro, cyano, lower alkylthio, OR.sup.11, wherein R.sup.11 is hydrogen, lower alkyl, lower alkenyl, lower alkynyl, henyl, lower alkoxyphenyl, nitrophenyl, phenyl (lower) alkyl, cyanophenyl (lower) alkyl, benzoyl, tetrahydropyranyl, pyridyl, trifluoromethylpyridyl, pyrimidinyl, benzothiazolyl, quinolyl, benzoyl (lower) alkyl, benzosulfonyl or lower alkylbenezenesulfonyl, or --CH.sup.2 --Z--R.sup.12, wherein Z is --O--, --S--, or --NR.sup.13 -- wherein R.sup.13 is hydrogen or lower alkyl, R.sup.12 is phenyl, halophenyl, lower alkoxyphenyl, pyridyl, or pyrimidinyl; R.sup.4 is hydrogen, alkyl, alkoxy, halogen, nitro, cyano or halogenated alkyl; M is an oxygen atom, S(O).sub.i (in which i is 0, 1 or 2), NR.sup.16 (in which R.sup.16 is hydrogen, alkyl or acyl) or a single bond; n is 0 or 1, provided that, when R.sup.3 is imidazol-1-yl, n is 1; and .about. indicates an E- or Z-isomer or a mixture thereof; or a salt thereof.