Patent ID: 6093730
Filing Date: 2000-07-25
Classification: A61K,A61P,C07D,C07K

Abstract:
A compound of the formula I, or a physiologically active salt thereof: ##STR7## in which R.sup.1 is hydrogen or chlorine;R.sup.2 is hydrogen, (C.sub.1 -C.sub.8)-alkyl, (C.sub.1 -C.sub.8)-alkoxy, chlorine, trifluoromethyl, hydroxyl, benzyloxy, which is unsubstituted or substituted by a substituent selected from the group consisting of (C.sub.1 -C.sub.5)-alkyl and (C.sub.1 -C.sub.5)-alkoxy, or fluoroalkoxy of the formulaO--[CH.sub.2 ].sub.x --C.sub.f H.sub.(2f+1-g) F.sub.gwherex=0 or 1,f=an integer from 1 to 5, andg=an integer from 1 to (2f+1);R.sup.3 is hydrogen, (C.sub.1 -C.sub.8)-alkyl, (C.sub.1 -C.sub.8)-alkoxy, fluorine, chlorine, cyano, trifluoromethyl, hydroxyl, benzyloxy which is unsubstituted or substituted by a substituent selected from the group consisting of (C.sub.1 -C.sub.5)-alkyl and (C.sub.1 -C.sub.5)-alkoxy, or fluoroalkoxy of the formulaO--[CH.sub.2 ].sub.x --C.sub.f H.sub.(2f+1-g) F.sub.gin which x, f, and g are as defined above; andR.sup.4 and R.sup.5 independently are hydrogen, (C.sub.1 -C.sub.5)-alkyl, fluorine, chlorine, bromine, trifluoromethyl, cyano, (C.sub.1 -C.sub.5)-alkoxy, or fluoroalkoxy of the formulaO--[CH.sub.2 ].sub.x --C.sub.f H.sub.(2f+1-g) F.sub.gin which x, f, and g are as defined above,with the proviso that R.sup.1, R.sup.2, R.sup.3, R.sup.4, and R.sup.5 are not all simultaneously hydrogen.