Patent ID: 6586183
Filing Date: 2003-07-01
Classification: C12Q

Abstract:
A diagnostic kit for predicting an individual's bronchodilating response to a &bgr;-agonist comprising a set of genotyping oligonucleotides, wherein said set comprises a first oligonucleotide for genotyping PS3, a second oligonucleotide for genotyping PS9 and a third oligonucleotide for genotyping PS11 in the &bgr;2AR gene packaged in a container, wherein PS3 is located in the &bgr;2AR gene at a nucleotide position corresponding to nucleotide 934 in SEQ ID NO:1, PS9 is located in the &bgr;2AR gene at a nucleotide position corresponding to nucleotide 1633 in SEQ ID NO:1, and PS11 is located late in the &bgr;2AR gene at a nucleotide position corresponding to nucleotide 1839 in SEQ ID NO;1, wherein each of the first, second and third oligonucleotides is selected from the group consisting of an allele specific oligonucleotide probe, an allele specific oligonucleotide primer, and a primer extension oligonucleotide.