Patent ID: 8946293
Filing Date: 2015-02-03
Classification: A61K,A61P

Abstract:
1. A method of treating acute stroke, traumatic brain injury, spinal cord injury, myocardial infarction, shock, organ ischemia, ventricular arrhythmias, ischemic injury, hypoxia/ischemia, or other injuries, conditions, and disorders, in a subject in need of treatment, comprising administration of a first bolus and a second bolus of glyburide followed by a continuous infusion of glyburide to a subject in need of treatment, said administration comprising: (a) a first bolus administration of glyburide; (b) a second bolus administration of glyburide, after said first bolus, and (c) a first continuous infusion administration of glyburide after said second bolus administration of glyburide effective to provide a substantially steady level of glyburide in the blood of said subject over a desired period of time.