Patent ID: 8987291
Filing Date: 2015-03-24
Classification: A61K,A61P

Abstract:
1. A sustained-release oral pharmaceutical composition comprising within a single dosage form: a hydrophilic matrix; a therapeutically effective amount of an opioid selected from the group consisting of hydrocodone, tramadol, salts thereof, and combinations thereof; a salt of a non-steroidal anti-inflammatory drug (NSAID) selected from the group consisting of a salt of naproxen, diclofenac, ibuprofen, and combinations thereof; and a pharmaceutically acceptable anionic surfactant selected from the group consisting of sodium lauryl sulfate, docusate sodium, docusate calcium, and combinations thereof; wherein the opioid, the salt of an NSAID, and the anionic surfactant are within the hydrophilic matrix.