Patent ID: 8779154
Filing Date: 2014-07-15
Classification: A61P,C07D

Abstract:
1. A compound represented by formula (X): wherein: Ring A is a 6 membered aryl ring wherein the members of the ring are independently —CZ; Y is an aryl optionally substituted with one to two substituents independently selected from lower alkyl and halo; or an optionally substituted heteroaryl provided that when the heteroaryl is a five-membered ring it is selected from the group consisting of furyl, thienyl, pyrrolyl, oxazolyl, thiazolyl, isoxazolyl, pyrazolyl, isothiazolyl, triazolyl, thiadiazolyl, isothiazolyl and tetrazolyl; B is —C(R each X Z is a substituent selected from the group consisting of hydrogen, alkyl, alkoxy, alkyl sulfanyl, alkylamino, dialkylamino, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, heterocyclyl, aryl, heteroaryl, aralkyl, heteraralkyl, haloalkyl, —C(O)NR L is —NRCH each R each R R R r is 1, 2, 3, or 4; p is 0, 1, or 2; and provided that when r is 1, X or a pharmaceutically acceptable salt or prodrug thereof.