Patent ID: 6440487
Filing Date: 2002-08-27
Classification: A61F,A61K,A61N

Abstract:
A method of producing a radioactive transition metal stent, comprising one or more transition metals, wherein the transition metal stent surface is chemically bound to a radioactive material, comprising:(i) providing a solution of dehydrated phosphorus-32 enriched metaphosphoric acid; (ii) mixing the phosphorus-32 enriched metaphosphoric acid with an inert polymer to form an emulsion; (iii) stabilizing the emulsion; (iv) immersing a transition metal stent in the stabilized emulsion; (v) removing the stent from the emulsion; (vi) washing and drying the stent to obtain the radioactive transition metal stent; and (vii) immersing the stent from step (vi) in a suitable non-polar solvent with a low dielectric constant to remove the residual polymer.