Patent ID: 8148540
Filing Date: 2012-04-03
Classification: A61P,C07D,Y02P

Abstract:
1. A compound having a formula selected from the group consisting of: wherein a) R′ R′ n′ is 1 or 2, R R′ R′ is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms optionally substituted by at least one oxo, halo, nitro, cyano, alkenyl of 2 to 6 carbon atoms, halogen, amino, —OH, protected —OH, —OR, —NHCOH, —NHCOR″, —NHCOOR″, —COOH, —COOR″, —C(C m is 0, 1 or 2; R′ m is 0, 1 or 2; n is 1 or 2; —ZH is selected from the group consisting of —(CH n″ is 0 or 1, R′ m is defined above with the proviso that ZH is not —(CH Y′ is selected from the group consisting of —COH, —COR″, —COOR″, —CONH —CH Y′ —SO Y′ Y′ A is hydrogen or a nitrogen protective group, and R9 is a leaving group and their acid addition salts.