Patent ID: 8057398
Filing Date: 2011-11-15
Classification: A61B

Abstract:
1. A computer implemented method for monitoring and analysis of cardiovascular signals based on state-space estimation methods, comprising: (a) implementing a statistical state-space model for cardiovascular signals, said statistical model includes a method for limiting said cardiovascular signals' instantaneous frequency to physiologic limits based on enforcing limits on one or more estimated state variables, and said state-space method makes use of an instantaneous phase update clipping function based on innovations e(n) to improve stability and robustness, wherein said innovations e(n)=y(n)−h[{circumflex over (χ)}(n|n−1)] are obtained by subtracting the predicted measurement h[{circumflex over (χ)}(n|n−1)] based on the predicted state {circumflex over (χ)}(n|n−1)from the observations y(n); (b) initializing said statistical state-space model; and (c) processing said cardiovascular signals using a device with a processor to estimate a set of clinically relevant cardiovascular parameters based on said statistical state-space model using a state-space estimation method.