Patent ID: 7470433
Filing Date: 2008-12-30
Classification: A61K

Abstract:
1. A gel formulation for transdermal or transmucosal administration of an active agent, the formulation comprising: at least one active agent comprising estrogen; a gelling agent and a delivery vehicle comprising a C 2 to C 4 alkanol, a polyalcohol, and a permeation enhancer of monoalkyl ether of diethylene glycol present in an amount sufficient to provide permeation enhancement of the active agent through dermal or mucosal surfaces; wherein the formulation is substantially free of long-chain fatty alcohols, long-chain fatty acids, and long-chain fatty esters in order to avoid undesirable odor and irritation effects caused by such compounds during use of the formulation; provided that a progestin is not present in the formulation.