Patent ID: 6291678
Filing Date: 2001-09-18
Classification: C07D

Abstract:
A compound of Formula I (D(-)) or Formula I (L(+)) ##STR108##wherein R.sup.1 is ##STR109##wherein X is O, orn is zero, andR.sup.4 is H,R.sup.2 is --(CH.sub.2).sub.q --Y wherein Y is ##STR110##wherein R.sup.5 is as defined above, and R.sup.6, R.sup.6a, R.sup.6b, R.sup.6c, R.sup.6d are the same or different and are H,alkyl,alkenyl,alkynyl,cycloalkyl, orOR.sup.5 wherein R.sup.5 is as defined above, ##STR111##wherein R.sup.5, R.sup.6, R.sup.6a, R.sup.6b, R.sup.6c, and R.sup.6d are as defined above, ##STR112##wherein p is zero or an integer of 1 to 2, and R.sup.5, R.sup.5a, R.sup.6, R.sup.6c, and R.sup.6d are as defined above, or ##STR113##wherein p, R.sup.5, R.sup.5a, R.sup.6, R.sup.6c, and R.sup.6d are as defined above, and q is an integer of 3 to 6, ##STR114##wherein u is zero or an integer of one, and p and y are as defined above, ##STR115##wherein u and Y are as defined above, ##STR116##wherein Z is ##STR117##wherein R.sup.5, R.sup.6, R.sup.6a, R.sup.6b, R.sup.6c, and R.sup.6d are as defined above, or ##STR118##wherein p, R.sup.5, R.sup.5a, R.sup.6, R.sup.6c, and R.sup.6d are as defined above, and wherein u is as defined above, ##STR119##wherein u, p, and z are as defined above, ##STR120##wherein u, p, and z are as defined above, ##STR121##wherein u, R.sup.5a, and Y are as defined above, ##STR122##wherein u, R.sup.5a, and Y are as defined above, ##STR123##wherein u, R.sup.5a, and Y are as defined above, ##STR124##wherein u, R.sup.5a, R.sup.5 and Y are as defined above, ##STR125##wherein u, R.sup.5a, and Y are as defined above, or ##STR126##wherein u, R.sup.5a, and Y are as defined above; andR.sup.3 is H,--CO.sub.2 R.sup.7 wherein R.sup.7 is alkyl,cycloalkyl,cycloalkylalkyl,arylalkyl, oraryl,or an addition salt thereof.