Patent ID: 8349607
Filing Date: 2013-01-08
Classification: A01N,A61P,C12N

Abstract:
1. A method of silencing a target gene in a second cell or a second organism comprising introducing into said second cell or second organism, in which said target gene has not been silenced, either (a) a construct transcribable into short antisense RNA molecules (SARMs) and short sense RNA molecules (SSRMs), collectively short RNA molecules (SRMs), wherein the SSRMs and SARMs consist of 20-30 nucleotides; wherein said SARMs have been identified as present in a first organism wherein the same gene has been silenced and said SARMs are complementary to, and can base pair with, target RNA transcribed from said gene that is silenced in said first organism, and said SSRMs correspond to the target RNA in said first organism; or (b) introducing said SRMs themselves into said second cell or second organism.