Patent ID: 7714130
Filing Date: 2010-05-11
Classification: C07D

Abstract:
1. A method for preparing a compound having Formula II: or a pharmaceutically acceptable salt thereof, wherein B is (CR D is optionally substituted quinoxaline, wherein the substituents are selected from one or more of —V—H, —V-halogen, —V—N k is 0, 1, 2, or 3; R A is optionally substituted phenyl, wherein the substituents are selected from one or more of —V—H, —V-halogen, —V—N R alternatively, R R R which comprises reacting a compound having Formula I: wherein A and R 1 -R 12 are as defined above; with a compound having formula: wherein D, k and R 13 and R 14 are as defined above, and L g is halogen or OSO 2 R 32 , wherein R 32 is an optionally substituted alkyl, wherein the substitutents are selected from one or more of —V-halogen, —V—N an optionally substituted aryl, wherein the substituents are selected from one or more of —V—H, —V-halogen, —V—N alternatively, R an optionally substituted fluoroalkyl, wherein the substituents are selected from one or more of C in an organic solvent in the presence of a base; and optionally converting the compound of Formula II to a pharmaceutically acceptable salt.