Patent ID: 6288119
Filing Date: 2001-09-11
Classification: A61K,A61P,C07C

Abstract:
An 11,15-O-dialkyl prostaglandin E derivative of formula (I) ##STR30##(wherein R is oxo or halogen atom, R.sup.1 and R.sup.2 are each independently C1-4 alkyl, R.sup.3 is C1-10 alkyl, C2-10 alkenyl, C2-10 alkenyl, or C1-10 alkyl, C2-10 alkenyl or C2-10 alkynyl substituted by phenyl, phenoxy, C3-7 cycloalkyl or C3-7 cycloalkyloxy, wherein phenyl and cycloalkyl may be substituted by 1-3 of C1-4 alkyl, C1-4 alkoxy, halogen, trihalomethyl or nitro, and {character pullout} is bond or double-bond, or a non-toxic salts thereof or cyclodextrin clathrates thereof.