Patent ID: 6153739
Filing Date: 2000-11-28
Classification: A61P,C12N

Abstract:
An isolated nucleic acid molecule comprising a polynucleotide sequence selected from the group consisting of:(a) a polynucleotide sequence encoding amino acid residues 1 to 348 of SEQ ID NO:2;(b) a polynucleotide sequence encoding amino acid residues 2 to 348 of SEQ ID NO:2;(c) a polynucleotide sequence encoding a fragment of the human uridine diphosphate galactose-4-epimerase polypeptide of SEQ ID NO:2, wherein said fragment has epimerase activity;(d) a polynucleotide sequence encoding an antigenic polypeptide fragment of the human uridine diphosphate galactose-4-epimerase polypeptide of SEQ ID NO:2;(e) a polynucleotide sequence encoding the full-length human uridine diphosphate galactose-4-epimerase polypeptide encoded by the human cDNA clone contained in ATCC Deposit No. 97112;(f) a polynucleotide sequence encoding the full-length human uridine diphosphate galactose-4-epimerase polypeptide, excluding the N-terminal methionine residue, encoded by the human cDNA clone contained in ATCC Deposit No. 97112;(g) a polynucleotide sequence encoding a mature human uridine diphosphate galactose-4-epimerase polypeptide encoded by the human cDNA clone contained in ATCC Deposit No. 97112;(h) a polynucleotide sequence encoding at least 50 contiguous amino acid residues of a human uridine diphosphate galactose-4-epimerase polypeptide encoded by the human cDNA clone contained in ATCC Deposit No. 97112;(i) a polynucleotide sequence encoding a fragment of a human uridine diphosphate galactose-4-epimerase polypeptide encoded by the human cDNA clone contained in ATCC Deposit No. 97112, wherein said fragment has epimerase activity; and(j) a polynucleotide sequence encoding an antigenic polypeptide fragment of a human uridine diphosphate galactose-4-epimerase polypeptide encoded by the human cDNA clone contained in ATCC Deposit No. 97112.