Patent ID: 6017914
Filing Date: 2000-01-25
Classification: C07D

Abstract:
A compound of formula I ##STR6## wherein R.sup.1 is --COOR.sup.6, --C.tbd.CH, --CH.dbd.CH.sub.2, or --COCH.sub.3 ;R.sup.2 is --H, --Cl, --F, C.sub.1 -C.sub.4 alkyl, --OH, --O(C.sub.1 -C.sub.4 alkyl), --OCO(C.sub.1 -C.sub.6 alkyl), --O--CO--O(C.sub.1 -C.sub.6 alkyl), --O--CO--AR, --OSO.sub.2 (C.sub.2 -C.sub.6 alkyl), or --O--CO--OAR, where AR is optionally substituted phenyl;R.sup.3 and R.sup.4 are, independently, R.sup.2 ;R.sup.5 is 1-piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-1-pyrrolidino, 4-morpholino, dimethylamino, diethylamino, diisopropylamino, or 1-hexamethyleneimino;R.sup.6 is --H or C.sub.1 -C.sub.4 alkyl;X is --CO-- or --CH.sub.2 --; andn is 2 or 3; with the proviso that when R.sup.2 is --OH, --O(C.sub.1 -C.sub.4 alkyl), --OCO(C.sub.1 -C.sub.6 alkyl), --O--CO--O(C.sub.1 -C.sub.6 alkyl), or --O--CO--AR, then R.sup.1 is not --COCH.sub.3 ;or a pharmaceutically acceptable salt or solvate thereof.