Patent ID: 8735387
Filing Date: 2014-05-27
Classification: A61P,C07D

Abstract:
1. A compound selected from any of the following compounds: 2-(3-fluoro-phenyl)-5-morpholin-4-ylmethyl-7-propoxy-oxazolo[5,4-d]pyrimidine, 3-(5-morpholin-4-ylmethyl-7-propoxy-oxazolo[5,4-d]pyrimidin-2-yl)-phenol, 2-(2-chloro-5-fluoro-phenyl)-5-[1,4]oxazepan-4-ylmethyl-7-propoxy-oxazolo[5,4-d]pyrimidine, 2-(2-chloro-pyridin-4-yl)-5-morpholin-4-ylmethyl-7-propoxy-oxazolo[5,4-d]pyrimidine, 5-cyclohexylmethyl-7-propoxy-2-m-tolyl-oxazolo[5,4-d]pyrimidine, 5-(1-phenyl-ethyl)-7-propoxy-2-m-tolyl-oxazolo[5,4-d]pyrimidine, 3-{4-[5-(4-chloro-benzyl)-7-propoxy-oxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-propane-1,2-diol, 1-{4-[5-(4-chloro-benzyl)-7-ethoxy-oxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-3-diethylamino-propan-2-ol, 1-{4-[5-(4-chloro-benzyl)-7-ethoxy-oxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-3-morpholin-4-yl-propan-2-ol, 1-hydroxy-cyclopropanecarboxylic acid (3-{4-[5-(4-chloro-benzyl)-7-ethoxy-oxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-2-hydroxy-propyl)-amide, N-(3-{4-[5-(4-chloro-benzyl)-7-propoxy-oxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-2-hydroxy-propyl)-acetamide, 4-{4-[5-(4-chloro-benzyl)-7-propoxy-oxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-butyric acid, (2-{4-[5-(4-chloro-benzyl)-7-propoxy-oxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-acetylamino)-acetic acid, 3-(3-{4-[5-(4-chloro-benzyl)-7-propoxy-oxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-2-hydroxy-propylamino)-propionic acid, (S)-1-(2-{4-[5-(4-chloro-benzyl)-7-propoxy-oxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-acetyl)-pyrrolidine-2-carboxylic acid, 1-(5-tert-butyl-4H-[1,2,4]triazole-3-sulfonyl)-3-{4-[5-(4-chloro-benzyl)-7-ethoxy-oxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-propan-2-ol, and 4-[5-(4-chloro-benzyl)-7-ethoxy-oxazolo[5,4-d]pyrimidin-2-yl]-2-fluoro-phenol, including any stereoisomeric forms, any mixture of stereoisomeric forms in any ratio, or a physiologically acceptable salt thereof, or a physiologically acceptable solvate of any of them.