Patent ID: 7799800
Filing Date: 2010-09-21
Classification: C07D

Abstract:
1. A compound of the following Formula I: wherein: R the alkylene, alkenylene, and alkynylene groups are optionally interrupted with one or more —O— groups; L is a bond or a functional linking group selected from the group consisting of —NH—S(O) R R″ is selected from the group consisting of: hydrogen; alkyl; alkenyl; aryl; heteroaryl; heterocyclyl; alkylene-Y-alkyl; alkylene-Y-alkenyl; alkylene-Y-aryl; and alkyl or alkenyl substituted by one or more substituents selected from the group consisting of: wherein aryl is phenyl, naphthyl, biphenyl, fluorenyl or indenyl; heteroaryl is furyl, thienyl, pyridyl, quinolinyl, isoquinolinyl, indolyl, isoindolyl, triazolyl, pyrrolyl, tetrazolyl, imidazolyl, pyrazolyl, oxazolyl, thiazolyl, benzofuranyl, benzothiophenyl, carbazolyl, benzoxazolyl, pyrimidinyl, benzimidazolyl, quinoxalinyl, benzothiazolyl, naphthyridinyl, isoxazolyl, isothiazolyl, purinyl, quinazolinyl, pyrazinyl, or 1-oxidopyridyl; and heterocyclyl is the fully saturated or partially unsaturated derivative of any one of the above heteroaryl groups, pyrrolidinyl, tetrahydrofuranyl, morpholinyl, thiomorpholinyl, piperidinyl, piperazinyl, thiazolidinyl, imidazolidinyl, isothiazolidinyl, tetrahydropyranyl, quinuclidinyl, or homopiperidinyl; wherein: Y is —O— or —S(O) R each R is independently selected from the group consisting of each R with the proviso that when L is —NH—S(O) or a pharmaceutically acceptable salt thereof.