Patent ID: 8481077
Filing Date: 2013-07-09
Classification: A61K,A61P

Abstract:
1. A method for delivering oxygen to a patient, comprising administering via injection or infusion to the patient a composition, comprising a suspension comprising microbubbles and a carrier, wherein the microbubbles comprise a lipid envelope and a gas core, wherein the gas core comprises oxygen and does not contain a fluorinated gas, wherein the lipid envelope comprises one or more lipids, wherein the lipid is a phospholipid comprising acyl chains having an average length of 10 to 24 carbons, wherein the outer surface of the lipid envelope forms a protective border, and wherein the suspension comprises at least 40% oxygen by volume, wherein the patient is experiencing local or systemic hypoxia, wherein the composition is administered in an effective amount to increase the concentration of oxygen in the patient's blood, tissue or organ in need of oxygen, and wherein the microbubbles release the effective amount of oxygen within 0.5 seconds to 1 minute following administration to the patient.