Patent ID: 6071712
Filing Date: 2000-06-06
Classification: C12P,Y10S

Abstract:
A process for preparing a compound of the formula: ##STR8## where R is substituted or unsubstituted phenyl, substituted or unsubstituted heterocyclyl, or substituted or unsubstituted heteroaryl, X is hydrogen or a pharmaceutically acceptable cation and Y is a pharmaceutically acceptable cation, which process comprises treating a compound of the formula: ##STR9## where X is hydrogen or a pharmaceutically acceptable cation, Y is a pharmaceutically acceptable cation and acyl is an ester-forming group with an esterase or a lipase active in a pH range of about 3.5 to 8.0, using conditions under which the enzyme is active, to hydrolyze the acyl group to form the alcohol, such that the target compound is produced.