Patent ID: 8518431
Filing Date: 2013-08-27
Classification: A61L,A61P

Abstract:
1. A method of constructing a target cell-carrying medical implant device, said method comprising the steps of: a. providing a porous biocompatible medical implant comprising a solid exterior surface having a plurality of pores; b. providing a solution comprised of the following components: (i) a non-polar liquid, (ii) a polar liquid and (ii) a plurality of amphiphilic molecules composed of hydrophobic tail ends and hydrophilic head ends, wherein said head ends have a binding affinity for one or more target cells, further wherein said solution components assemble into non-polar-liquid-filled micelles or micelle-like constructs; c. contacting said micelles or micelle-like constructs with a solution containing target cells to which the hydrophilic head ends of said amphiphilic molecules have a binding affinity and inducing said micelles or micelle-like constructs to bind said target cells and form micelle-target cell units; and d. introducing said micelle-target cell units into the pores of said implant exterior surface so as to yield a medical implant device having target cells immobilized within said exterior surface pores.