Patent ID: 6033631
Filing Date: 2000-03-07
Classification: B01J,C07H,C07K,C40B

Abstract:
An apparatus for synthesizing oligomers immobilized on solid phase particles in a particle suspension, said apparatus comprising;(a) a reaction vessel having a top opening for receiving fluids and gases, and a bottom opening having filter means through which nonparticulate fluids may freely pass;(b) first delivery means for delivering a gas and/or solvent into the reaction vessel through the top opening;(c) second delivery means for conducting the following operations through the bottom opening (i) delivering a gas into the reaction vessel to effect mixing of the particulate suspension, (ii) removing fluids from the reaction vessel; (iii) introducing a reagent into the reaction vessel from an associated reaction vessel, and (iv) returning unused reagent from the reaction vessel to the associated reagent vessel, and(d) control means connected to the first and second delivery means for controlling the operation thereof.