Patent ID: 6489477
Filing Date: 2002-12-03
Classification: A61P,C07D

Abstract:
A compound having the formula: or a pharmaceutically acceptable salt thereof, whereinR1 is 2-benzimidazole; R2 is phenyl, optionally substituted with one to five substituents, each substituent independently being chloro, fluoro, bromo, C1-C4alkyl, trifluoromethyl, hydroxy, or carboxy; L1 is C1-C4alkyl, C1-C4alkenyl, C1-C4alkynyl, C1-C4alkoxy, aminoC1-C4alkyl, hydroxyC1-C4alkyl, carbonyl, cycloC3-C6alkyl or aminocarbonyl; L2 is phenylmethyl or phenylmethylaminocarbonyl, optionally substituted with chloro, fluoro, bromo, or methyl; and optionally substituted at any of the 3, 4, 5, 6, 7, or 8 positions independently with X, wherein X is hydroxy, amino, C1-C4alkylamino, di(C1-C4)alkylamino, C1-C4alkyl, â€”OCOOC1-C4alkyl, â€”NHCOOC1-C4alkyl, or â€”OCONHC1-C4alkyl.