Patent ID: 7473688
Filing Date: 2009-01-06
Classification: A61P,C07D

Abstract:
1. A compound of formula I wherein: R R R R R R R R or NR R R or NR provided that if NR 9 R 10 is pyrrolidinyl, piperidinyl, piperazinyl, homomorpholinyl, homopiperidinyl, morpholinyl, or thiomorpholinyl it cannot be substituted with 0-2 substituents selected from alkyl, hydroxy, amino, alkylamino, dialkylamino, or pyridinyl; or NR or NR 9 R 10 taken together is a [2.2.1] or [2.2.2] bridged bicyclic amine wherein the bicycle contains 0-1 NR 6 , NCO 2 R 6 , or O; R R R R or R R R the dashed line is either a single bond or a double bond, provided that if the dashed line is a single bond, the carbon bearing the asterisk is either of the R configuration, the S configuration, or a mixture of R and S configurations; or a pharmaceutically acceptable salt thereof.