Patent ID: 6803187
Filing Date: 2004-10-12
Classification: C12Q

Abstract:
Method for determining the susceptibility to antiviral drugs of HIV viruses in a biological sample comprising polynucleic acids, with said method comprising:a) releasing, isolating or concentrating the polynucleic, acids present in the sample; b) amplifying part of a protease gene of HIV comprising codons 82 and 84 from the polynucleic acids with at least one suitable primer pair; c) hybridizing the polynucleic acids of step a) or b) with probes having the sequence of SEQ ID NO:267 and SEQ ID NO:354, or probes having sequence complementary to SEQ ID NO:267 and SEQ ID NO:354; wherein said probes are immobilized on a solid support; and d) inferring from the result of step c) whether or not a mutation giving rise to drug resistance is present in said polynucleic acids.