Patent ID: 6664235
Filing Date: 2003-12-16
Classification: A61K,A61P

Abstract:
A medicament which comprises as an active ingredient a compound represented by the following formula: wherein R1 represents a hydrogen atom or an optionally substituted C1-6 alkyl group; R2 represents an optionally substituted phenyl group, an optionally substituted C1-20 alkyl group, an optionally substituted C1-20 alkenyl group, or â€”(CH2)kâ€”[NHâ€”(CH2)mâ€”NH]nâ€”Y or â€”(CH2)kâ€”[NHâ€”(CH2CH2O)mâˆ’1â€”CH2CH2NH]nâ€”Y in which Y represents a phosphatidylethanolamine residue or a polyglutamic acid residue, k and m independently represent an integer of from 2 to 10, n represents 0 or 1, provided that when n represents 1, Y represents a phosphatidylethanolamine residue; one of R3 and R4 is a hydrogen atom and the other one of R3 and R4 is a halogen atom or an optionally substituted hydroxyl group; and R5, R6, R7 and R8 independently represent an optionally substituted hydroxyl group;or a pharmaceutically acceptable salt, hydrate or solvate thereof.