Patent ID: 8389572
Filing Date: 2013-03-05
Classification: A61K,A61P

Abstract:
1. A pharmaceutical composition for delivery of CO, comprising as an active ingredient a compound represented by formula (I) or formula (II) below: wherein:— M is a transition metal selected from group 6, 7, 8 or 9 of the periodic table; Y is a counteranion; q is the charge of Y and is selected from 1, 2 or 3; x is 2, 3 or 4; z is 0 or 1, and x, z and p satisfy the equation where g is the group number of M in the periodic table, and where p is 0 or 1when g is 6; or p is 0 when g is 7, 8 or 9; L is a ligand selected from H, halide, C C (—OC(═O)R (—SC(═S)NR wherein M′ is Fe or Ru; Y is a counteranion; q is the charge of Y and is selected from 1, 2 or 3; L′ is a ligand selected from either a first group consisting of H, halide, —NO (—OC(═O)NR —SC(O)0R —N(C(═O)R a second group consisting of OR PR R z=0 when L′ is from said first group and z=1 when L′ is from said second group; and wherein in formula (I) and formula (I1):— Cp is selected from: where r, s and t are each independently selected from 1, 2, 3 or 4; and R -[Alk] n is 0 or 1; Alk is a C Q each R R each R (—C(═O)OR R