Patent ID: 8546355
Filing Date: 2013-10-01
Classification: A61K,A61L,A61Q,C11D,D06M

Abstract:
1. A composition suitable for capturing unwanted molecules, the composition comprising functionally-available cyclodextrin, a cyclodextrin-incompatible surfactant having a complexation constant with cyclodextrin of greater than about 5,000 M −1 , and a cyclodextrin-compatible surfactant having a complexation constant with cyclodextrin of less than about 5,000 M −1 , wherein the cyclodextrin-compatible surfactant and the cyclodextrin-incompatible surfactant are combined to form a first mixture and the first mixture is subsequently combined with cyclodextrin to form the composition, wherein the concentration of functionally-available cyclodextrin is at least about 0.001%, and further wherein the functionally available cyclodextrin is present in an uncomplexed form, or is complexed with material having a cyclodextrin complexation constant of less than about 5,000 M −1 so that the cyclodextrin remains functionally available in the composition to complex with and thereby capture the unwanted molecules, wherein the cyclodextrin compatible surfactant is hydrogenated castor oil and the cyclodextrin-incompatible surfactant has the following formula: wherein R