Patent ID: 6241719
Filing Date: 2001-06-05
Classification: A61F,A61K,A61M,A61N

Abstract:
A method for endovascular formation of a radioactive stent at a vascular site which method comprises:(a) endovascularly delivering to a vascular site a liquid permeable balloon catheter, said balloon cathether comprising a balloon membrane at least a portion of which is liquid permeable;(b) inflating said balloon to contact the vascular walls at said vascular site by delivering thereto a composition, said composition comprising a biocompatible polymer, a biocompatible solvent and a water insoluble radioisotope; and(c) in situ forming a radioactive stent at the vascular site by maintaining positive pressure on said balloon wherein at least a portion of said composition permeates through said permeable balloon membrane into the vascular site whereupon the composition forms a solid mass which contacts and adheres to the vascular walls thereby forming a radioactive stent at said vascular site.