Patent ID: 8702988
Filing Date: 2014-04-22
Classification: B01J

Abstract:
1. A method for covalently modifying an inorganic substrate, comprising the steps of: (a) equilibrating the inorganic substrate in an atmosphere having a defined relative humidity of less than 40% to provide a controlled amount of water on the surface of the inorganic substrate, thereby enhancing batch to batch reproducibility; (b) covalently modifying the inorganic substrate with at least one silane in the presence of an inert solvent; and (c) further covalently modifying the inorganic substrate with an endcapping silane, wherein the silane has the formula: wherein R α is 0 or 1; β is 0-30; γ is 0, 1 or 2; δ is 0-3; R Q is independently selected from —NHC(O)—, —C(O)NH—, —OC(O)NH—, —NHC(O)O—, —NHC(O)NH—, —NCO, —CHOHCHOH—, —CH X is a leaving group.