Patent ID: 9145545
Filing Date: 2015-09-29
Classification: A61K,A61P,C12N,G01N,Y10T

Abstract:
1. An isolated sub-population of spore-like cells, comprising cells expressing two or more markers selected from the group consisting of: octamer-binding transcription factor 4 (Oct4), zinc finger protein 296 (Zfp296), cryptic family protein 1B (cripto), growth differentiation factor-3 (Gdf3), undifferentiated embryonic cell transcription factor 1 (UtF1), embryonic stem cell associated transcript 1 (Ecat1), embryonic stem cell-specific gene 1 (Esg1), sex determining region Y-box 2 (Sox2), paired box protein 6 (Pax6), nestin, stem cell antigen 1 (SCA-1), cluster of differentiation protein 29 (CD29), cluster of differentiation protein 34 (CD34), cluster of differentiation protein 90 (CD90), B1 integrin, tyrosine-protein kinase (cKit), surfactant protein C (SP-C), Clara cell 10 protein (CC10), splicing factor 1 (SF1), dosage-sensitive sex reversal gene 1 (DAX1), and superior cervical ganglion-10 protein (SCG10), isolated from post-natal animal tissue selected from the group consisting of ectodermal, mesodermal and endodermal tissue, wherein the cells remain viable following oxygen deprivation for at least four hours.