Patent ID: 9040079
Filing Date: 2015-05-26
Classification: A61K,A61P

Abstract:
1. A chemical formulation for the delivery of a hydrophobic drug to a choroidal neovascular region, comprising: a carrier for solubilizing a hydrophobic drug; and a therapeutically effective amount of hydrophobic photosensitize; wherein said carrier is a liposomal bilayer comprising synthetic phospholipids that are a mixture of dipalmitoyl phosphatidyl choline (DPPC), dipalmitoyl phosphatidyl glycerol (DPPG), and pegylated distearoyl phosphatidyl ethanol amine (PEG-DSPE) present in a weight ratio of DPPC:DPPG:PEG-DSPE of 9:1:1 and said drug is present in said liposomal bilayer; and wherein said hydrophobic photosensitizer is temoporfin.