Patent ID: 9145453
Filing Date: 2015-09-29
Classification: A23L,A61K,A61P,C07K

Abstract:
1. A method of promoting weight loss in a patient in need thereof, said method comprising orally administering to said patient an effective amount of an orally bioavailable composition comprising gelatin and additional constituents, wherein said additional components comprise dihexadecyl phosphate, cholesterol and an amphiphilic lipid, the amphiphilic lipid being selected from the group consisting of 1,2-distearoyl-sn-glycero-3-phosphocholine, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine, 1,2-dimyristoyl-sn-glycero-3-phosphocholine, 1,2-distearoyl-sn-glycero-3-phosphate, 1,2-dipalmitoyl-sn-glycero-3-phosphate, 1,2-dimyristoyl-sn-glycero-3-phosphate, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine, 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl), and 1,2-dipalmitoyl-sn-glycero-3-[phospho-rac-(1-glycerol)], said composition further comprising at least one biotin-derived targeting agent selected from the group consisting of biotin DHPE and biotin-X-DHPE, wherein said gelatin actively reversibly interacts with one or more of said additional constituents, wherein oral administration of said biotin-derived targeting agent within said composition to said patient promotes weight loss in said patient.