Patent ID: 7625889
Filing Date: 2009-12-01
Classification: A61P,C07D

Abstract:
1. A compound, including enantiomers, stereoisomers, and tautomers of said compound and pharmaceutically acceptable salts thereof, with said compound having the general structure shown in formula I: wherein: denotes a single bond between X and Y; X is O or S; Y is CHR or CO; Z is NR; A, B and E are the same or different and independently from each other are CR; D is either CH Ar is selected from the group consisting of substituted or unsubstituted phenyl, pyridinyl, pyrazinyl, furanyl and thiophenyl wherein the substituents are selected from the group consisting of fluorine, chlorine, C each R is independently chosen from hydrogen, halogen, CN, C(O)NR R the substituents are selected from the group consisting of phenyl, fluorophenyl, trifluoromethylphenyl, pyridinyl, thiophenyl, furanyl C R