Patent ID: 7687459
Filing Date: 2010-03-30
Classification: A61K,A61P,C07D,C07K

Abstract:
1. A compound represented by the formula (I) or (II): as well as the pharmaceutically acceptable salts and esters thereof, wherein: A is selected from H, —(C═O)—O—R each R (i) aryl; (ii) substituted aryl; (iii) heteroaryl; (iv) substituted heteroaryl; (v) Heterocycloalkyl; (vi) substituted heterocycloalkyl; (vii) —C (viii) substituted —C (ix) —C (x) substituted —C (xi) —C (xii) substituted —C each R (i) hydrogen; (ii) aryl; (iii) substituted aryl; (iv) heteroaryl; (v) substituted heteroaryl; (vi) heterocycloalkyl; (vii) substituted heterocycloalkyl; (viii) —C (ix) substituted —C (x) —C (xi) substituted —C (xii) —C (xiii) substituted —C G is selected from —OH, —NHS(O) each R each R L is selected from —CH U and V are independently selected from the group consisting of: X is selected from the group consisting of: (i) oxygen; (ii) sulfur; and (iii) NR Y is absent or is selected from the group consisting of: Z is selected from aryl, substituted aryl, heteroaryl, and substituted heteroaryl; Rx and Ry are each independently selected from a group consisting of: or when Rx is not hydrogen and Y is not absent, Rx, taken together with W and Y form a ring structure shown in formula III or IV: wherein w is selected from CH or when Rx is not hydrogen and Y is not absent, Rx, when taken together with W, Z, and Y form a ring structure as shown in formula V or VI: g=0, 1, 2; j=0, 1, 2, 3, or 4; k=1, 2, or 3; m=0, 1, or 2; n=1, or 2; and