Patent ID: 8367670
Filing Date: 2013-02-05
Classification: A61K,A61P,C07D,Y02A

Abstract:
1. A compound of Formula II: or a pharmaceutically acceptable salt or tautomeric enol thereof, wherein: Y—Z is —CR L R X D is phenylene, biphenylene, or pyridinyl, wherein said phenylene, biphenylene, or pyridinyl is substituted with one or two -L each L each R n is 0, 1, 2, 3, 4 or 5; R R R R R R wherein each substituted alkyl, substituted alkenyl, substituted alkynyl, substituted cyclopropyl, substituted cyclobutyl, substituted cyclopentyl, substituted cyclohexyl, substituted tetrahydropyranyl, substituted furanyl, or substituted pyrrolidinyl, substituted alkylene, substituted heteroalkylene, substituted alkenylene, substituted alkynylene is independently substituted with one to four substituents selected from the group consisting of -halogen, —R, —O