Patent ID: 6630503
Filing Date: 2003-10-07
Classification: A61K,A61P,C07D,C07K

Abstract:
A compound of the formula:R3â€”Lâ€”Lâ€²â€”R1 whereinR1 is optionally substituted pyrrolidinyl substituted with a â€”SO2-optionally substituted phenyl group; Lâ€² is a hydrocarbon linker moiety having 1 carbon chain atom and is (i) terminally attached to R1 by â€”NHC(&boxH;O)â€” and (ii) substituted with â€”COOH; L is C1-4 alkyl terminally attached to R3 by â€”C(&boxH;O)NHâ€”; and R3 is of the formula R4â€”Y5â€”N(R5)â€”CH(R6)â€” where R6 is alkyl; R5 is hydrogen or alkyl; Y5 is â€”C(&boxH;O)â€” and R4 is an optionally substituted aralkyl; or a pharmaceutically acceptable salt thereof.