Patent ID: 6723553
Filing Date: 2004-04-20
Classification: C12N

Abstract:
An isolated human site-1 protease promoter region comprising a sequence selected from:(a) the nucleotide sequence set forth as SEQ ID NO: 2 or a fragment thereof exhibiting site-1 protease promoter activity; (b) the complementary strand of (a); and (c) a nucleic acid sequence that hybridizes to (a) or (b) under conditions of hybridization in 0.5 M NaHPO4, 7% sodium dodecyl sulfite (SDS), 1 mM EDTA at 65Â° C., and washing in 0.1Ã—SSC/0.1% SDS at 68Â° C., wherein the nucleic acid exhibits site 1-protease promoter activity.