Patent ID: 6545053
Filing Date: 2003-04-08
Classification: A61P,C07C,C07D

Abstract:
A compound represented by the general formula (I) or a salt thereof: in which R represents hydrogen atom or methyl, R1 stands for hydrogen atom, halogen atom, hydroxy, benzyloxy, amino or hydroxymethyl, R2 stands for hydrogen atom, hydroxymethyl, NHR3, SO2NR4R4â€² or nitro, wherein R3 is hydrogen atom, methyl, SO2R5, formyl or CONHR6â€², with R5 being lower alkyl, benzyl or NR4R4â€² and R6â€² being hydrogen atom or lower alkyl, and R4 and R4â€² may be identical with or different from each other and stand each for hydrogen atom, lower alkyl or benzyl, R6 represents hydrogen atom or lower alkyl, X is methylene, both R7 and R8 are hydrogen atom and R9 stands for hydrogen atom, amino, acetyl amino or hydroxy, and *1 indicates an asymmetric carbon atom and *2 indicates that the carbon atom is asymmetric provided that R6 is lower alkyl.