Patent ID: 6423507
Filing Date: 2002-07-23
Classification: A61K,A61P,C07K,C12N

Abstract:
A process of screening for an antagonist/inhibitor of a protease polypeptide having the same protease function as the polypeptide having the sequence of amino acids 1 to 214 of SEQ ID NO:2, where said protease polypeptide is encoded by a polynucleotide which is at least 95% identical to a polynucleotide encoding amino acids 1 to 214 of SEQ ID NO:2, and said protease polypeptide is not rabbit OC-2, comprising:contacting said protease polypeptide, a potential inhibitor for said protease polypeptide and a substrate for said protease polypeptide; and determining whether said potential inhibitor inhibits said protease polypeptide from action on said substrate.