Patent ID: 6218404
Filing Date: 2001-04-17
Classification: C07D

Abstract:
A compound having the Formula IIId: ##STR120##or a pharmaceutically acceptable salt thereof;whereinW is an adamantyl group or an optionally substituted aryl group;X is (CH.sub.2).sub.m,Y.sub.1 is hydrogen, alkyl, hydroxyalkyl, an aminoalkyl group, an amidoalkyl group, a ureidoalkyl group, or a guanidinoalkyl group;R.sub.1 is hydrogen, hydroxy, halo, alkylcarboxy, optionally substituted aryl, optionally substituted aralkyl, optionally substituted aryloxyalkyl, optionally substituted benzyloxyalkyl, a heterocyclic group, a heterocyclic substituted alkyl group, heteroaryl, or a heteroaryl substituted alkyl group;n is 0, 1, 2, 3, 4, 5, or 6; andm is 1;with the proviso that when W is an adamantyl group, then Y may further be an optionally substituted aralkyl group, or an optionally substituted aryl group, and with the further proviso that when R.sub.1 is H and Y.sub.1 is CH, W is not phenyl or t-butyl substituted phenyl.