Patent ID: 6673611
Filing Date: 2004-01-06
Classification: A61K,A61P,C12N

Abstract:
A nucleic acid molecule having the formula XIII:iB-rprprprprprprpDsDsDsDsDsDsDsDsDsrprprprprprpr-iB wherein each r is independently a 2â€²-O-alkyl nucleotide, each D is independently a deoxyribonucleotide or 2â€²-arabinofluoro nucleotide, each s is independently a phosphorothioate, phosphorodithioate, 5â€²-thiophosphate, 3â€²-thiophosphate, or methylphosphonate internucleotide linkage, each p is independently a phosphodiester internucleotide linkage, and each iB is independently an inverted abasic moiety.