Patent ID: 6043089
Filing Date: 2000-03-28
Classification: C12M,C12N

Abstract:
A skin cell culture which comprises:(1) a skin cell culture matrix comprising a collagen sponge, a collagen sheet or a collagen gel, said matrix being prepared in a structure provided with a plurality of projections, wherein said matrix has a thickness of at least 1 mm, and each of said projections has a width of at least 1 mm, said width being measured in at least one direction across a cross-section of said projections, and(2) skin-derived cells seeded and cultured on said matrix in said structure provided with a plurality of projections,wherein the resulting matrix bearing a culture of skin-derived cells is provided with a plurality of penetrating pores by the operation of said structure provided with a plurality of projections immediately before said skin cell culture is used to cover a skin defect.