Patent ID: 9120791
Filing Date: 2015-09-01
Classification: A61K,A61N,A61P,C07D

Abstract:
1. A compound of formula (I): wherein: X and Y represent a carbon atom or a nitrogen atom, wherein X and Y may not simultaneously represent two carbon atoms or two nitrogen atoms; the Het moiety of the group  represents an optionally substituted, aromatic or non-aromnatic ring composed of 5, 6 or 7 ring members, which ring may have, in addition to the nitrogen represented by X or by Y, from one to 3 heteroatoms selected independently from oxygen, sulphur and nitrogen, wherein the nitrogen atom may be substituted by a hydrogen atom, a linear or branched (C R  or R R R R R it being understood that: “aryl” means a phenyl, naphthyl, biphenyl or indenyl group, “heteroaryl” means any mono- or bi-cyclic group composed of from 5 to 10 ring members, having at least one aromatic moiety and containing from 1 to 3 hetero atoms selected from oxygen, sulphur and nitrogen, “cycloalkyl” means any mono- or bi-cyclic non-aromatic carbocyclic group containing from 4 to 10 ring members, wherein the alkyl, aryl, heteroaryl, cycloalkyl and heterocycloalkyl groups so defined may be optionally substituted by from 1 to 3 groups selected from optionally substituted linear or branched (C 1 -C 6 )alkyl, (C 3 -C 6 )spiro, linear or branched (C 1 -C 6 )alkoxy, (C 1 -C 6 )alkyl-S—, hydroxy, oxo (or N-oxide where appropriate), nitro, cyano, —COOR′, NR′R″, linear or branched (C 1 -C 6 )polyhaloalkyl, trifluoromethoxy, (C 1 -C 6 )alkylsulphonyl or halogen, wherein R′ and R″ independently of one another represent a hydrogen atom or a linear or branched (C 1 -C 6 )alkyl group, and wherein the Het moiety of the group defined hereinbefore may be optionally substituted by a group selected from linear or branched (C 1 -C 6 )alkyl, hydroxy, NR 1 ′R 1 ″ and halogen, wherein R 1 ′ and R 1 ″ independently of one another represent a hydrogen atom or a linear or branched (C 1 -C 6 )alkyl group, or an enantiomer, a diastereoisomer, or an addition salt thereof with a pharmaceutically acceptable acid or base.