Patent ID: 9005599
Filing Date: 2015-04-14
Classification: A61K,A61P,C07K,C12N

Abstract:
1. A method for treating or protecting a human subject exposed to a chemical agent comprising administering to the subject a composition comprising an isolated cell population comprising human umbilical cord perivascular cells (HUCPVCs) having a 3G5+, CD45−, CD44+ phenotype, wherein the cell population is characterized by rapid proliferation and the presence of human progenitor cells, and the HUCPVCs in said cell population are genetically modified to express a butyrylcholinesterase (BChE) polypeptide or to increase the expression of an endogenous butyrylcholinesterase (BChE) polypeptide, and wherein said composition treats or protects said subject exposed to said chemical agent.