Patent ID: 6602892
Filing Date: 2003-08-05
Classification: A61K,G01N,Y10S,Y10T

Abstract:
A method for determining a nicotine dosage necessary to achieve a target nicotine serum concentration in an individual patient who is ceasing smoking, said method comprising:(A) measuring a patient nicotine concentration while the patient is still smoking; and (B) determining the nicotine dosage as follows: (i) for male patients: determining the values of at least a body mass factor and a cumulative smoking factor; and determining the dosage to achieve the target nicotine serum concentration based on the patient's measured nicotine concentration, the body mass factor value, and the cumulative smoking factor value; or (ii) for female patients: determining at least the value of a psychological dependence factor and age; and determining the dosage to achieve the target nicotine serum concentration based on the patient's measured nicotine concentration, the psychological dependence factor value and the age.