Patent ID: 7312041
Filing Date: 2007-12-25
Classification: A61K,C07K,C12Q,G01N,Y10S

Abstract:
1. A method of detecting the presence of an oncogenic human papilloma virus (HPV) protein in a sample, said method comprising: contacting a sample suspected of containing an oncogenic HPV E6 protein with a PDZ domain polypeptide; and detecting any binding of said oncogenic HPV E6 protein in said sample to said PDZ domain polypeptide; wherein binding of said oncogenic HPV E6 protein to said PDZ domain polypeptide indicates the presence of an oncogenic HPV E6 protein in said sample and wherein said PDZ domain polypeptide is less than 1000 amino acids in length and comprises the amino acid sequence of MAGI-1 PDZ domain 2.