Patent ID: 7754458
Filing Date: 2010-07-13
Classification: A61K,C07K

Abstract:
1. A crystal of hepatocyte growth factor beta chain (HGF β-chain) complexed with tyrosine kinase Met receptor (Met Receptor) comprising an HGF β-chain comprising an amino acid sequence comprising SEQ ID NO:1 complexed with an extracellular fragment of a Met Receptor, wherein the extracellular fragment of a Met Receptor comprises an amino acid sequence comprising SEQ ID NO:3, and wherein the crystal has a space group symmetry of P2 1 2 1 2, and comprises a unit cell having the dimensions of a, b, and c, where a is about 137.1 Å, b is about 186.4 Å, and c is about 66.7 Å.