Patent ID: 8834938
Filing Date: 2014-09-16
Classification: A61K,A61P

Abstract:
1. A method of inhibiting damage to the small intestine in a human subject resulting from chemotherapeutic treatment of cancer cells in the human subject, comprising: a) administering to the subject arsenic and/or one or more compounds of arsenic in an amount from about 31 μg/kg/day to about 125 μg/kg/day; and b) administering to the subject a therapeutically effective amount of one or more chemotherapeutic agents that activate p53, from one to eight days after the administration of the arsenic and/or one or more compounds of arsenic, wherein the arsenic and/or one or more compounds of arsenic suppress p53 activity and inhibit damage to the small intestine in the human subject resulting from administration of the one or more chemotherapeutic agents to the human subject.