Patent ID: 7572806
Filing Date: 2009-08-11
Classification: A61K,A61P,C04B,C07D

Abstract:
1. A method for treating a patient suffering from or at risk of a disease or condition for which PPAR modulation provides a therapeutic benefit, comprising administering to said patient a PPAR modulator having the chemical structure of Formula I, namely wherein U, V, W, X, and Y are independently CR R R R R R R R R R Z is O or S; and n=1, or 2; or pharmaceutically acceptable salt thereof, wherein said disease or condition is selected from the group consisting of obesity, hyperlipidemia, dyslipidemia, hypertriglyceridemia, hypoalphalipoproteinemia, Syndrome X, Type II diabetes mellitus, Type I diabetes, hyperinsulinemia, impaired glucose tolerance, insulin resistance, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic cataracts, hypertension, coronary artery disease, heart failure, atherosclerosis, eczema, psoriasis, colitis, and regulation of appetite and food intake.