Patent ID: 7955602
Filing Date: 2011-06-07
Classification: A61K,G01N

Abstract:
1. A method for determining the efficacy of an anti-cancer agent during treatment of lung cancer in a subject comprising: (a) quantitatively detecting levels of Annexin I and Annexin II proteins in a biological sample derived from a subject with lung cancer prior to treatment for lung cancer; (b) detecting levels of Annexin I and Annexin II proteins in biological samples derived from the subject during treatment for lung cancer; and (c) determining that the anti-cancer agent is efficacious for the treatment of lung cancer in the subject by comparing the levels of Annexin I and Annexin II proteins detected in the subject's sample prior to treatment with the levels of Annexin I and Annexin II proteins detected in the samples derived from the subject during treatment, and identifying a decrease in the levels of one or both of the Annexin I and Annexin II proteins in the samples derived from the subject during treatment for lung cancer.