Patent ID: 6177104
Filing Date: 2001-01-23
Classification: A61K

Abstract:
A rapidly dissolving particulate support matrix, comprising:a first polypeptide component having a predetermined net charge;a second polypeptide component having a predetermined net charge of the same sign as the net charge of the first polypeptide component; anda bulking agent and wherein the first polypeptide component and the second polypeptide component together comprise about 2% to 35% by weight of the particulate support matrix and wherein the bulking agent comprises about 45% to 97% by weight of the particulate support matrix; andwherein the second polypeptide component has a solubility in aqueous solution greater than that of the first polypeptide component; andwherein when the support matrix is introduced into an aqueous environment the support matrix is substantially completely disintegrable within less than about 20 seconds.