Patent ID: 6265402
Filing Date: 2001-07-24
Classification: A61P,C07D

Abstract:
A method for preventing or treating inflammatory diseases comprising administrating to a person in need thereof a 2-phenylmorpholin-5-one derivative having the formula (I): ##STR62##wherein R.sub.1 represents a substituted or unsubstituted C.sub.1 to C.sub.8 allyl group; a substituted or unsubstituted C.sub.3 to C.sub.7 cycloalkyl group; or indanyl group, R.sub.2 represents a C.sub.1 to C.sub.4 alkyl group, R.sub.3 represents a hydrogen atom: a substituted or unsubstituted C.sub.1 to C.sub.5 alkyl group; a substituted or unsubstituted C.sub.3 to C.sub.7 cycloalkyl group; a substituted or unsubstituted aryl group which may include at least one hetero atom selected from the group consisting of an oxygen atom, a nitrogen atom and a sulfur atom; or an acyl group, R.sub.4 represents a hydrogen atom; a substituted or unsubstituted C.sub.1 to C.sub.6 alkyl group; or a substituted or unsubstituted aryl group which may include at least one hetero atom selected from the group consisting of an oxygen atom, a nitrogen atom and a sulfur atom, R.sub.5 and R.sub.6 each independently represent a hydrogen atom; a substituted or unsubstituted C.sub.1 to C.sub.5 alkyl group; a substituted or unsubstituted C.sub.3 to C.sub.7 cycloalkyl group; or a substituted or unsubstituted aryl group which may include at least one hetero atom selected from the group consisting of an oxygen atom, a nitrogen atom and a sulfur atom,an optical isomer thereof, or a pharmacologically acceptable salt thereof, or a hydrate or solvate thereof and a pharmacologically acceptable carrier.