Patent ID: 7989600
Filing Date: 2011-08-02
Classification: C07H

Abstract:
1. A compound according to Formula I: wherein M represents a macrolide subunit of the substructure II: wherein: alkyl represents a linear or branched saturated monovalent hydrocarbon radical of one to ten carbon atoms, unsubstituted or substituted with one up to five substituents selected from halogen, hydroxy, alkoxy, acyl, acylamino cyano, amino, N—(C alkenyl represents a linear or branched monovalent hydrocarbon radical of two to ten carbon atoms which has at least one double carbon-carbon bond, unsubstituted or substituted with the same groups as defined above for alkyl group; alkynyl represents a linear or branched monovalent hydrocarbon radical, having a straight-chain or a branched-chain of two to ten, and containing from one to three triple carbon-carbon bonds, unsubstituted or substituted with the same groups as defined above for alkyl group; cycloalkyl represents a cyclic group having three to eight carbon atoms having a single ring optionally fused to an aryl or heteroaryl group, or optionally fused to a saturated ring, cycloalkyl is unsubstituted or substituted with one or more substituents selected from halogen, hydroxy, C aryl represents an unsaturated aromatic carbocyclic group having 6-14 carbon atoms having a single ring or multiple fused rings, optionally further fused to an aliphatic or aryl group, aryl is unsubstituted or substituted with one or more substituents selected from halogen, hydroxy, C heteroaryl represents a monocyclic or a bicyclic aromatic hydrocarbon ring having from 2 to 10 carbon atoms and from 1 to 4 heteroatoms selected from O, S and N, optionally fused to another heteroaryl, aryl or aliphatic cyclic group, heteroaryl is unsubstituted or substituted with the same substituents as defined above for aryl group; and heterocyclic represents a saturated or unsaturated group having a single or multiple rings and from 1 to 10 carbon atoms and from 1-4 heteroatoms selected from N, S and O, wherein in a fused ring system the other ring or rings can be aryl or heteroaryl, heterocyclic group is unsubstituted or substituted as specified above for alkyl group.