Patent ID: 7390637
Filing Date: 2008-06-24
Classification: A61K,C07K,C10M

Abstract:
1. An isolated polynucleotide comprising a polynucleotide sequence selected from the group consisting of: (a) a polynucleotide sequence encoding a polypeptide consisting of amino acid residues 1 to 207 of SEQ ID NO:2; (b) a polynucleotide sequence encoding a polypeptide consisting of amino acid residues 2 to 207 of SEQ ID NO:2; (c) a polynucleotide sequence encoding a polypeptide consisting of amino acid residues 28 to 207 of SEQ ID NO:2; (d) a polynucleotide sequence encoding a polypeptide consisting of amino acid residues 30 to 207 of SEQ ID NO:2; (e) a polynucleotide sequence encoding a polypeptide consisting of amino acid residues 7 to 207 of SEQ ID NO:2; (f) a polynucleotide sequence encoding a polypeptide consisting of the full-length keratinocyte derived interferon (KDI) polypeptide having the amino acid sequence encoded by the human HKAPI15 cDNA contained in ATCC Deposit No. 203500; (g) a polynucleotide sequence encoding a polypeptide consisting of the full-length polypeptide having the amino acid sequence encoded by the human HKAPI15 cDNA contained in ATCC Deposit No. 203500 excluding the N-terminal methionine; (h) a polynucleotide sequence encoding a polypeptide consisting of the mature KDI polypeptide having the amino acid sequence encoded by the human HKAPI15 cDNA contained in ATCC Deposit No. 203500; wherein said nucleotide sequence in (a)-(h) encodes a polypeptide having KDI activity; and (i) a polynucleotide sequence complementary to any of the polynucleotide sequences in (a), (b), (c), (d), (e), (f), (g), or (h) above.