Patent ID: 7700288
Filing Date: 2010-04-20
Classification: C12Q,G01N

Abstract:
1. A method for diagnosing B-cell lymphoma in an animal, comprising the steps of: (a) determining the amount of miR-155 in a B-cell sample isolated from the animal; (b) determining the amount of miR-155 in normal B-cells; (c) comparing the amount of miR-155 in the B-cell sample isolated from the animal with the amount of miR-155 in normal B-cells; and (d) diagnosing B-cell lymphoma in the animal if the amount of miR-155 in the B-cell sample isolated from the animal is higher than the amount of miR-155 in the normal B-cells, wherein the B-cell lymphoma is diffuse large B-cell lymphoma (DLBCL) or marginal zone (MZ) B-cell lymphoma.