Patent ID: 8374677
Filing Date: 2013-02-12
Classification: A61B,A61N,G01R

Abstract:
1. An MRI-guided interventional system for guiding an interventional device with respect to a body of a patient in an MRI-guided procedure, the system comprising a trajectory guide frame including: a base having a patient access aperture therein and configured to be secured to the body of the patient; a targeting cannula mounted on the base for movement relative thereto, the targeting cannula having an elongate guide bore extending axially therethrough and an inlet and an outlet at opposed ends of the guide bore, the guide bore defining a trajectory axis extending through the inlet and the outlet and being configured to guide placement of the interventional device; a tubular cannula guide member defining a cannula guide member passage and having an inlet and outlet on opposed ends of the cannula guide member passage; and a plurality of MRI-visible fiducial markers mounted on the base, wherein the MRI-visible fiducial markers are relatively positioned in an asymmetric layout to facilitate positive determination of an orientation of the base in free space from an MR image; wherein the trajectory guide frame is operable to move the targeting cannula relative to the base to position the trajectory axis to a desired intrabody trajectory to guide placement of the interventional device in vivo; wherein the inlet tapers from an outer diameter distal from the guide bore to an inner diameter proximate the guide bore to guide and facilitate insertion of the interventional device into the guide bore; wherein the targeting cannula is slidably mounted within the cannula guide member passage to move between extended and retracted positions; wherein the inlet of the targeting cannula is downstream of the inlet of the cannula guide member; wherein the plurality of MRI-visible fiducial markers includes at least first, second and third MRI-visible fiducial markers each located on a common circle; and wherein a circumferential spacing between the first and second MRI-visible fiducial markers is less than a circumferential spacing between the first and third MRI-visible fiducial markers.