Patent ID: 7855215
Filing Date: 2010-12-21
Classification: A61P,C07D

Abstract:
1. A compound of Formula I: wherein p is 1, 2 or 3; m is 0, 1, 2 or 3; n is 0, 1, 2 or 3; A is CR X, and Y are N, and Z is C-R3; each R each R R R G is a group Ar or represents CN; Ar is selected from: where R substituted or unsubstituted lower alkyl, lower alkenyl, lower alkynyl, lower alkoxy, amino, a carbocyclic group, a heterocyclic group or mono- or di-substituted amino, being substituted by a substituted or unsubstituted hydrocarbyl moiety, the hydrocarbyl moiety selected from lower alkyl, cycloalkyl, lower alkanoyl; or any two of -L-R or any two of -L-R wherein the carb comprises C wherein the heterocyclic group especially comprises five, six or seven in-chain atoms of which at least one is a heteroatom selected from N, O or S and is substituted or unsubstituted and wherein L is a covalent bond or a moiety which comprises 1, 2, 3 or 4 in-chain atoms selected from carbon, oxygen, sulphur and nitrogen or salts, esters, or N-oxides thereof.