Patent ID: 8183347
Filing Date: 2012-05-22
Classification: A61K,A61P,C07K,C12N

Abstract:
1. An isolated antibody that binds to TAT226, or antigen-binding fragment thereof, wherein the antibody comprises: a heavy chain variable domain comprising an HVR-H1 comprising the amino acid sequence of SEQ ID NO:4, an HVR-H2 comprising the amino acid sequence of SEQ ID NO:5, and an HVR-H3 comprising an amino acid sequence selected from SEQ ID NO:6-10; a light chain variable domain comprising an HVR-L1 comprising the amino acid sequence of SEQ ID NO:12, an HVR-L2 comprising the amino acid sequence of SEQ ID NO:13, and an HVR-L3 comprising an amino acid sequence selected from SEQ ID NO:14-18.