Patent ID: 6063807
Filing Date: 2000-05-16
Classification: A61K,A61P

Abstract:
A compound of the formulaA B (I)in the form of non-toxic salt, whereinA is a cyclo-oxygenase inhibitor presenting a carboxy function;B is ##STR2## R.sub.1 is selected from the group consisting of hydrogen, nitro and phenyl optionally substituted by one or more members selected from the group consisting of cyano, nitro, trifluoromethyl, lower alkyl and lower alkoxy,R.sub.2 is selected from the group consisting of a) lower alkyl, lower alkylthio, alkylthioalkyl, aryl optionally substituted by one or more substituents selected from the group consisting of halo, cyano, nitro, trifluoromethyl, lower alkyl and lower alkoxy and b) amino optionally substituted by a member selected from the group consisting of nitro, amino, lower alkyl and phenyl optionally substituted by one or more substituents selected from the group consisting of halo, cyano, nitro, trifluoromethyl, lower alkyl and a lower alkoxy, with the proviso that when A is acetylsalicylic acid and R.sub.1 is a hydrogen atom, then R.sub.2 is neither an aryl nor an phenylamino optionally substituted.