Patent ID: 7030111
Filing Date: 2006-04-18
Classification: A61P,C07C,C07D,G01N

Abstract:
1. A compound that abrogates the cell cycle G2 checkpoint when administered to a cell, wherein the compound has following structure: where either or both of benzene are substituted with pyrazine, pyrimidine, piperazine, morpholine, cyclohexane, piperizine or pyridine; R1 is a halogen, bromine (Br), chlorine (Cl), fluorine (F), iodine (I), amino (NH 2 ), nitro (NO 2 ), hydroxy (OH), O-methyl (OCH 3 ), or methyl (CH 3 ); R2, R3, R4, R5 and R6 is bromine (Br), chlorine (Cl), fluorine (F), iodine (I), amino (NH 2 ), nitro (NO 2 ), methyl (CH 3 ), O-methyl (OCH 3 ), hydroxy (OH), CH(CH 3 ) 2 , CHO, CHOCH 3 , O(CH 2 )nCH 3 , OCO(C 6 H 12 )Cl, COOCH 3 or hydrogen; X1 is nitrogen (NH), oxygen (O) or sulfate (S); and X2 is oxygen (O) or sulfate (S).