Patent ID: 7419971
Filing Date: 2008-09-02
Classification: A61K,A61P,Y10S

Abstract:
1. A combination comprising: (a) a compound having the formula. wherein R Z is carbonyl or β-hydroxymethylene; X is Cl or F; R Y is —OH, —SH or —OCOR and the dotted line in ring A indicates that the 1,2-linkage is saturated or unsaturated; and (b) a compound having the formula: wherein: R is H or C Z X R and the dotted line is defined as above; with the proviso that when R is C in a combined synergistic anti-inflammatory effective amount; the amount of compound of formula (II) being sufficient to enhance the anti-inflammatory activity or duration of action, or both, of said compound having formula (Ia) or (Ib).