Patent ID: 6086864
Filing Date: 2000-07-11
Classification: A61P,C07C

Abstract:
A water-soluble, rigid backbone, polythiourca oligomer corresponding to the formula: ##STR11## wherein R is hydrogen, C.sub.1 -C.sub.4 alkyl, phenyl or phenyl substituted with 0 to 2 R.sup.1 groups and up to 3 substituents independently selected from chloro, bromo or C.sub.1 -C.sub.4 alkyl;R.sup.1 represents --SO.sub.3 R.sup.2, --CO.sub.2 R.sup.2, --PO.sub.3 R.sup.2 or --OPO.sub.3 R.sup.2 ;R.sup.2 is hydrogen or a pharmaceutically acceptable cation;R.sup.3 is --R, where R is defined as above;X represents ##STR12## m is an integer 0 or 1; n is an integer from 3-50;with the proviso that when m is 0, both R and R.sup.3 are not simultaneously hydrogen;and with the additional proviso that at least one R.sup.1 of X is --SO.sub.3 R.sup.2.