Patent ID: 6127355
Filing Date: 2000-10-03
Classification: A61K,C07D,C08G

Abstract:
A composition comprising the formula: ##STR20## wherein: D is a residue of a biologically active moiety selected from the group consisting of acyclovir, cyclosporin A, amoxicillin, fluconazole, and floxuridine;X is an electron withdrawing group;Y and Y' are independently O or S;(n) is zero (0) or a positive integer;R.sub.1 and R.sub.2 are independently selected from the group consisting of H, C.sub.1-6 alkyls, aryls, substituted aryls, aralkyls, heteroalkyls, substituted heteroalkyls and substituted C.sub.1-6 alkyls;R.sub.3 is a substantially non-antigenic polymer, C.sub.1-12 straight or branched alkyl or substituted alkyl, C.sub.5-8 cycloalkyl or substituted cycloalkyl, carboxyalkyl, carboalkoxy alkyl, dialkylaminoalkyl, phenylalkyl, phenylaryl or ##STR21## R.sub.4 and R.sub.5 are independently selected from the group consisting of H, C.sub.1-6 alkyls, aryls, substituted aryls, aralkyls, heteroalkyls, substituted heteroalkyls, and substituted C.sub.1-6 alkyls or jointly form a cyclic C.sub.5 -C.sub.7 ring.