Patent ID: 6509499
Filing Date: 2003-01-21
Classification: A61P,C07C,C07D

Abstract:
A compound of the formula 1 in whichP represents the radical (i): â€”(COâ€”NH)mSO2â€”R; or the radical (iii): R represents phenyl, benzyl, diphenylmethyl, naphthyl, cycloalkylalkyl in which the alkyl part is C1-C4 and the cycloalkyl part is C3-C7, or styryl, each of which is optionally substituted with one or more groups Z which may be identical or different; or R represents a C3-C5 aromatic heterocyclic radical comprising 1 or 2 hetero atoms O, S or N, said radical optionally being substituted with one or more groups Z, which may be identical or different, and optionally being fused to 1 or 2 phenyl rings which are optionally substituted with one or more groups Z, which may be identical or different; or R represents C1-C4 alkyl optionally substituted with one more halogen atoms, which may be identical or different, C3-C7 cycloalkyl, or cyclo (C3-C7) alkyl (C1-C4) alkyl; Z is halogen, C1-C4 alkyl, C1-C4 alkoxy, nitro, cyano, trifluoromethyl, trifluoromethoxy, (C2-C5) alkylamino, (C1-C4) alkylsulphonyl, (C1-C4) alkylthio or phenyl; X represents a hydrogen or halogen atom; m is 0; n is 0, 1 or 2; T1 and T2 represent, independently of each other, a hydrogen atom or a C1-C4 alkyl group, u is 0 or 1; A represents C1-C8 alkylene or the group Y is an integer 0, 1, 2, 3 or 4; A tautomeric form thereof or an addition salt thereof with a pharmaceutically acceptable base.