Patent ID: 6541230
Filing Date: 2003-04-01
Classification: A61P,C08G,C12N

Abstract:
A reusable polymeric sponge or foam for the detoxification of a diverse array of organophosphorus and/or organosulfur compounds comprising a plurality of enzymes or a cross-linked enzyme complex of said plurality of enzymes immobilized on the sponge or foam, said plurality of enzymes comprising multiple-enzymes selected from the group consisting of acetyicholinesterase (AChE), butyrylcholinesterase (BChE), triesterase, pseudocholinesterase, choline oxidase, peroxidase, organophosphate hydrolase (OPH), phosphotriesterase, paraoxonase, and laccase and an indicator embedded in the sponge of foam for measuring the capacity of the sponge or foam for detoxification of organophosphorus and/or organosulfur compounds, wherein the indicator is fluorescent, chemiluminescent or visible chromogen or is an electrode, and said indicator is encapsulated in a lipsome or is in a crushable packet.