Patent ID: 8747900
Filing Date: 2014-06-10
Classification: A61K,A61P

Abstract:
1. A rapid release cefuroximaxetil pharmaceutical dosage form comprising extruded pellets comprising: cefuroximaxetil; 20 to 30 wt.-% κ-carrageenan, relative to the total weight of the extruded pellets; tricalcium phosphate; and 1 to 10 wt.-% of sucrose ester relative to the total weight of the extruded pellets; wherein the weight ratio of cefuroximaxetil to κ-carrageenan is in the range from 1.5:1 to 3.5:1; wherein the weight ratio of tricalcium phosphate to κ-carrageenan is in the range from 1:1 to 1:10; and wherein said dosage form releases at least 75% of the cefuroximaxetil within 30 minutes upon exposure to aqueous medium at a pH of 6 to 7.