Patent ID: 8348922
Filing Date: 2013-01-08
Classification: A61N

Abstract:
1. A method for the iontophoretic transdermal delivery of a therapeutic agent to a patient in need thereof, the method comprising: applying a first and second patch to the skin of the patient, the first patch comprising a delivery electrode, a therapeutic agent and two lateral electrodes, the second patch comprising at least a delivery electrode; delivering a first current to the skin, the first current flowing between the delivery electrodes, the first current creating a first electromotive driving force to transport the therapeutic agent into the skin; delivering a second current to the skin, the second current flowing between the lateral electrodes of the first patch; the second current creating a second electromotive driving force to oscillate the therapeutic agent in a direction substantially parallel to a surface of the skin; and transporting the therapeutic agent across the skin using the first electromotive driving force to propel the agent into the skin, and the second electromotive driving force to oscillate the agent substantially parallel to the surface of the skin so that the agent is sieved through pathways of least diffusional resistance in the skin.