Patent ID: 6565875
Filing Date: 2003-05-20
Classification: A61K,A61P,Y10S

Abstract:
A method for eliciting neural fiber growth within the central nervous system to treat a patient with a neurologic disease or injury, comprising:gaining access to the central nervous system of the patient in need of such a treatment; and contacting the central nervous system with microspheres comprising a neuroactive molecule encapsulated within a polymer, wherein the micropsheres comprising an effective amount of neuroactive molecule are capable of eliciting neural fiber growth, said polymer (1) being permeable to the neuroactive molecule agent, (2) being biocompatible with the tissues of the central nervous system, (3) being biodegradable within the tissues of the central nervous system without producing toxic by-products of degradation, and (4) having kinetic characteristics that may be manipulated to allow for the permeation of the neuroactive molecule through the polymer at a controlled rate and a predetermined period of time, thereby eliciting neural fiber growth within the central nervous system of the patient.