Patent ID: 7666392
Filing Date: 2010-02-23
Classification: A61K

Abstract:
1. A cyclopeptide of formula I: wherein: R R R X is a 5 or 6-membered heterocycle or a linker comprising a hydrophilic moiety selected from the group consisting of hydroxyl, carbonyl, sulfonamide, sulfonate, phosphate, polar amino acid moiety, PEG moiety, sugar mimetic, and sugar moiety; Y is a 5 or 6-membered heterocycle, or a linker comprising a hydrophilic moiety selected from the group consisting of hydroxyl, carbonyl, sulfonamide, sulfonate, phosphate, polar amino acid moiety, PEG moiety, sugar mimetic, and sugar moiety; where at least one of X and Y, but not both X and Y is a 5 or 6-membered heterocycle; and w is 1, 2, 3, 4, or 5; wherein any one of X, Y, R