Patent ID: 8673586
Filing Date: 2014-03-18
Classification: A61K,A61P,C07H

Abstract:
1. A method of identifying a compound that inhibits or enhances the activity of a protein kinase comprising: a) contacting said protein kinase with a compound of formula I, being a derivative of a furanose or pyranose form of a monosaccharide, or a pharmaceutically acceptable salt thereof b) assaying the activity of said protein kinase in the presence of said compound of formula I and in the absence of said compound of formula I, wherein, when the activity of said protein kinase in the presence of said compound of formula I is higher than the activity of said protein kinase in the absence of said compound of formula I, said compound of formula I is an enhancer of the activity of said protein kinase, and when the activity of said protein kinase in the presence of said compound of formula I is lower than the activity of said protein kinase in the absence of said compound of formula I, said compound of formula I is an inhibitor of the activity of said protein kinase.