Patent ID: 6525060
Filing Date: 2003-02-25
Classification: A61K,A61P,C07C,C07D

Abstract:
A compound of formula (I) wherein:R1 is C3-5 alkyl optionally substituted by one or more halogen atoms; R2 is a phenyl group, optionally substituted by one or more fluorine atoms; R3 and R4 are both hydroxy; R is XOH, where X is CH2, OCH2CH2 or a bond; or a pharmaceutically acceptable salt or solvate thereof, or a solvate of such a salt provided that:when X is CH2 or a bond, R1 is not propyl; when X is CH2 and R1 is CH2CH2CF3, butyl or pentyl, the phenyl group at R2 must be substituted by fluorine; when X is OCH2CH2 and R1 is propyl, the phenyl group at R2 must be substituted by fluorine.