Patent ID: 6339072
Filing Date: 2002-01-15
Classification: A61K,A61P

Abstract:
A method of providing revascularization in a subject, comprising:(i) administering to a subject a pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent, and an active agent selected from the group consisting of: (a) a selective adenosine A2A receptor agonist, (b) the combination of a selective adenosine A1 antagonist and either a selective adenosine A2A receptor agonist or a non-selective adenosine agonist, and (c) a selective adenosine A1 antagonist in order to block the adenosine A1 receptor activation by endogenously-released adenosine; and (ii) practicing a revascularization procedure on said subject at a blood vessel site to remove an occlusion or to reroute blood flow through a bypass graft.