Patent ID: 6759528
Filing Date: 2004-07-06
Classification: C07K

Abstract:
An isolated polynucleotide selected from the group consisting of a polynucleotide encoding a collagen &agr;3(V) polypeptide, said polynucleotide encoding an amino acid sequence of SEQ ID NO:4, a polynucleotide having 80% identity to the polynucleotide encoding SEQ ID NO:4 over the entire length of the polynucleotide encoding SEQ ID NO:4, a polynucleotide that hybridizes to the polynucleotide encoding SEQ ID NO:4 on overnight incubation at 42Â° C. in a solution comprising 50% formamide, 5Ã—SSC (150 mM NaCl, 15 mM sodium citrate), 50 mM sodium phosphate (pH 7.6), 5Ã— Denhardt's solution, 10% Dextran Sulfate, and 20 micrograms/ml denatured, sheared salmon sperm DNA, followed by washing the filter in 0.1Ã—SSC at about 65Â° C. and a complement of any of the polynucleotide.