Patent ID: 6626538
Filing Date: 2003-09-30
Classification: A61B,A61F,Y10S

Abstract:
A method of designing an intraocular lens for surgical implantation in a phakic eye of a myopic patient wherein the design of the intraocular lens includes selecting a lens power to provide a predicted post-operative refraction in the eye of the patient, the method comprising the steps of:a. using a first lens power prediction model to make a prediction of lens powers for a plurality of test lenses having a common lens configuration using a first set of pre-operative measurements for each of a corresponding number of myopic test patient eyes, the first set of pre-operative measurements selected from a group of patient factors that includes pre-operative refraction, anterior chamber depth, and vertex distance; b. selecting test lenses having the predicted lens powers needed to provide the predicted post-operative refraction in the corresponding test patient eyes; c. surgically implanting the test lenses in the corresponding test patient eyes; d. obtaining post-operative measurements of the actual post-operative refraction achieved in each of the test patient eyes; e. performing a multiple regression analysis of the actual post-operative measurements as compared to the corresponding first set of pre-operative measurements to identify and quantify which of the patient factors has a statistically significant effect on accuracy of the first predicted post-operative refraction as compared to the actual post-operative refraction; f. using the identification and quantification of statistical significance determined by the multiple regression analysis to modify the first prediction model to create a second lens power prediction model using the identified patient factors; g. obtaining from the patient the pre-operative measurements of the patient factors as identified and used in the second lens power prediction model; and h. using the second lens power prediction model and pre-operative measurements obtained from the patient to select the lens power for the intraocular lens to be implanted in the patient.