Patent ID: 6551590
Filing Date: 2003-04-22
Classification: A61K,A61P,Y10S

Abstract:
A method for inducing liquefaction of a vitreous humor to treat a disorder of a mammalian eye, said method comprising:contacting with the vitreous humor of the mammalian eye an amount of a solution which contains hyaluronidase to provide a dose of at least 1 International Unit of hyaluronidase, said solution being free of thimerosal, essentially devoid of hyaluronic acid-lysing material having a molecular weight greater than 100,000 as determined by 10% SDS PAGE electrophoresis, essentially devoid of caseinolytic material having a molecular weight greater than 45,000 as determined by 15% SDS PAGE electrophoresis, and essentially devoid of gelatinolytic material having a molecular weight between 60,000 and 100,000 as determined by 10% SDS PAGE electrophoresis, and wherein said method is carried out for the purpose of accelerating the clearance of hemorrhagic blood from the vitreous humor of the mammalian eye.