Patent ID: 6126944
Filing Date: 2000-10-03
Classification: A61P,C07K,C12N,G01N

Abstract:
Recombinant herpes simplex virus gG-1 antigen produced by employing a recombinant baculovirus having a nontranslated polyhedrin gene leader sequence CTATAAAT (SEQ ID NO. 7) joined to the 5' end of a polyhedrin gene translation initiation codon ATG, and having the polyhedrin gene translation initiation codon ATG joined to the 5' end of the coding region of a foreign gene, without any extraneous nucleotide between the 5' end of the nontranslated polyhedrin gene leader sequence CTATAAAT (SEQ ID NO. 7), the polyhedrin gene translation initiation codon ATG and the 5' end of the coding region of a foreign gene, wherein said foreign gene is herpes simplex virus type 1 glycoprotein gene.