Patent ID: 6171614
Filing Date: 2001-01-09
Classification: A61K,B82Y,C07H,C07K,Y10S,Y10T

Abstract:
A self-assembling system comprising a glycophospholipid or a peptide-phospholipid conjugate, having a phospholipid moiety and a saccharide or peptide moiety joined by a diether linkage comprising a secondary or tertiary amine, said conjugate having the formula ##STR3##whereinR.sub.1 and R.sub.2 are independently selected from the group comprising straight or branched, unsubstituted or substituted, saturated or unsaturated acyl, alkyl, alkenyl, alkynyl and aryl groups;Y is a cation;X is a secondary or tertiary amine linker, comprising two to twenty carbon atoms, wherein a substituent group of the amine is selected independently from a group comprising a hydrogen, a straight or branched, unsubstituted or substituted alkyl, alkenyl, alkynyl and aryl groups; andZ is a saccharide, a peptide or a functionalized derivative thereof; and a member selected from the group consisting of a membrane, a bilayer, a film, a liposome and a carrier-vehicle.