Patent ID: 7029695
Filing Date: 2006-04-18
Classification: A61K

Abstract:
1. A liposomal formulation containing a compound that is: (i) a diester of a compound of formula A where: each ester is 1–25C; YCO is γ-glu or β-asp; G* is phenylglycine; Z is CH X is a hydrocarbon radical which is alkyl (6–8C), benzyl, or naphthyl; or a pharmaceutically acceptable salt thereof; or (ii) a compound of formula I where: R X is as defined above for formula A; or a pharmaceutically acceptable salt thereof where the lipids of the liposomal formulation consist of egg phosphatidylcholine and egg phosphatidylglycerol in a ratio of 0.75–1.25:0.75–1.25 by weight and the ratio of lipids to compound is 3.5–4.5:0.5–1.5 by weight.