Patent ID: 9102644
Filing Date: 2015-08-11
Classification: C07D

Abstract:
1. A method for the synthesis of 5-(chloromethyl)-2-furaldehyde (CMF) from saccharides, comprising (a) contacting saccharides in a pure or crude form, hydrochloric acid, and an organic solvent in a continuous, biphasic-flow reactor assembly at a temperature from about 60 degrees C. to about 200 degrees C. and under pressure from about 1 atmospheres to about 20 atmospheres producing a biphasic liquid mixture containing (x) an organic phase that contains CMF and (y) an aqueous acid phase; (b) separating the organic phase from the aqueous acid phase; (c) cooling the organic phase; and (d) after separating the organic phase from the aqueous acid phase, washing the organic phase with an inorganic base dissolved in aqueous solution at or below the inorganic base's solubility limit in water to create a state of pH not less than seven to remove Hydrothermal Carbon (HTC) dissolved or suspended in the organic phase, wherein the aqueous solution of an inorganic base is used at a minimum of 5% by volume of the total volume of the organic phase solution.