Patent ID: 8592225
Filing Date: 2013-11-26
Classification: B82Y

Abstract:
1. A nanopore structure for use in a biosensor, comprising: (a) a membrane which is less than about 200 nm thick; (b) a nanopore aperture through said membrane, having a diameter through said membrane of less than about 1 μm; (c) an annular overhang, comprising a gold surface shaped axially outwardly from the membrane, at an end of the aperture, the overhang shaped axially outwardly from the membrane and radially inwardly to narrow the walls of the nanopore aperture along a fixed axial distance, producing a reduced diameter and a reduced length relative to the original aperture, wherein said reduced diameter is between about 1 nm and about 100 nm, said reduced length is between about 5 and about 100 nm; and (d) a biopolymer probe molecule attached to the gold surface on the annular overhang.