Patent ID: 8954131
Filing Date: 2015-02-10
Classification: A61B,B82Y,G01R,H01F

Abstract:
1. A magnetic particle imaging (MPI) method of diagnosing certain cancers in which phagocytes selectively uptake iron-based nanoparticles, the MPI method comprising the steps of: directing a compound containing the iron-based nanoparticles to be selectively delivered via phagocyte uptake to a tumor site containing cells; allowing a predetermined time for the iron-based nanoparticles to be uptaken into the cells contained at the tumor site; performing magnetic particle imaging using a magnetic particle imaging device in order to detect a concentration of iron-based nanoparticles uptaken into the cells; analyzing image data provided by the magnetic particle imaging device in order to determine the concentration of iron-based nanoparticles indicative of the tumor site; and applying a predetermined magnetic field to the iron-based nanoparticles for a sufficient period in order to activate a magnetic core of the iron-based nanoparticles, thereby inducing hyperthermia destruction of the cells.