Patent ID: 7417054
Filing Date: 2008-08-26
Classification: A61P,C07D

Abstract:
1. A compound of formula (I): wherein one or two of X, Y, and Z is N, and the remaining of X, Y, and Z are CR L is —O— or —CH m is 0, 1, or 2; R R A) —C B) phenyl or pyridyl, optionally fused at two adjacent carbon ring members to a three- or four-membered hydrocarbon moiety to form a fused five- or six-membered aromatic ring, which moiety has one carbon atom replaced by >O, >S, >NH, or >N(C C) a 4-8 membered heterocyclic ring, said heterocyclic ring having a carbon atom which is the point of attachment, having 1 or 2 heteroatom members selected from >O, >S(O) D) a monocyclic aromatic hydrocarbon group having five or six ring atoms, having a carbon atom which is the point of attachment, having one carbon atom replaced by >O, >S, >NH, or >N(C where each of A)-D) is optionally mono-, di-, or tri-substituted with a moiety selected from the group consisting of —OH, —C or, alternatively, R R R Ar and enantiomers, diastereomers, hydrates, solvates thereof, and pharmaceutically acceptable salts, esters and amides thereof.