Patent ID: 7435552
Filing Date: 2008-10-14
Classification: C07K,C12Q,G01N,G16B

Abstract:
1. A method for identifying a compound that putatively modulates a taste receptor polypeptide comprising a human T1R2 polypeptide in a human subject comprising: (1) screening one or more compounds in a binding assay which identifies compounds that specifically bind to a human T1R2 polypeptide or which modulate (inhibit or enhance) the specific binding of another compound that specifically binds to said human T1R2 polypeptide wherein said T1R2 polypeptide is selected from the group consisting of: (2) identifying a compound that putatively modulates or elicits human T1R2-associated taste based on its specific binding to a human T1R2 polypeptide according to (a), (b), or (c), or its modulation (inhibition or enhancement) of the specific binding of another compound to a T1R2 polypeptide according to (a), (b), or (c).