Patent ID: 6262083
Filing Date: 2001-07-17
Classification: C07D

Abstract:
A novel genipin compound represented by the following formula (I)a : ##STR24##in whichR.sub.1 represents lower alkyl;R.sub.2 represents lower alkyl, pyridylcarbonyl, benzyl or benzoyl;R.sub.3 represents formyl, hydroxymethyl, azidomethyl, 1-hydroxyethyl, acetyl, methyl, hydroxy, pyridylcarbonyl, cyclopropyl, aminomethyl substituted or unsubstituted by (1,3-benzodioxolan-5-yl)carbonyl or 3,4,5-trimethoxybenzoyl, 1,3-benzodioxolan-5-yl, ureidomethyl substituted or unsubstituted by 3,4,5-trimethoxyphenyl or 2-chloro-6-methyl-3-pyridyl, thiomethyl substituted or unsubstituted by acetyl or 2-acetylamino2-ethoxycarbonyethyl, oxymethyl substituted or unsubstituted by benzoyl, pyridylcarbonyl or 3,4,5-trimethoxybenzoyl;provided that R.sub.3 is not methyl formyl, hydroxymethyl, acetyl, methylaminomethyl, acetylthiomethyl, benzoyloxymethyl or pyridylcarbonyloxymethyl when R.sub.1 is methyl, andits pharaceutically acceptable salts, or stereoisomers.