Patent ID: 8980884
Filing Date: 2015-03-17
Classification: A61K,A61P

Abstract:
1. A method of treating, delaying the onset of, slowing the progression of, or alleviating at least one symptom of Alzheimer's disease comprising administering to a patient a pharmaceutical composition comprising an effective amount of an inhibitor of ATase1 and/or ATase2, wherein the inhibitor of ATase1 and/or ATase2 is a compound selected from the compounds having the following formula: wherein: R R R wherein R 11 , R 12 , R 13 , and R 14 are each independently selected from hydrogen, halogen, —OH, —OR 9 , —SH, —SR 9 , —NH 2 , —NHR 9 , —NR 9 R 10 , and C 1 -C 10 alkyl, wherein R 9 and R 10 are independently selected from C 1 -C 5 alkyl; X X X wherein the X or pharmaceutically acceptable salts thereof; whereby Alzheimer's disease in the patient is delayed in onset, or slowed in progression, or whereby at least one symptom of Alzheimer's disease is alleviated.