Patent ID: 8946162
Filing Date: 2015-02-03
Classification: A61K,A61P,C12Y

Abstract:
1. A method of treating tumor diseases other than lung cancer comprising administering to a human patient in need thereof a recombinant, human, water-soluble, glycosylated with a sugar content greater than 10% by weight of total ACE2, dimeric angiotensin-converting-enzyme-2 (ACE2) polypeptide with ACE2 activity, wherein said recombinant, human, water-soluble, glycosylated with a sugar content greater than 10% by weight of total ACE2, dimeric ACE2 polypeptide comprises amino acids 18-740 of human wild type 805 amino acid ACE2, and wherein the tumor diseases are characterized by an increased angiotensin-II concentration in the tumor or in the tumor environment or in the tumor patient.