Patent ID: 6355430
Filing Date: 2002-03-12
Classification: C12Q

Abstract:
A method for determining whether a test compound alters the expression of KIAA0101 mRNA in a prostate cancer cell that expresses a gene encoding KIAA0101 mRNA, the method comprising:a) measuring the level of KIAA0101 mRNA present in a sample comprising the prostate cancer cells not exposed to the test compound; b) measuring the level of KIAA0101 mRNA present in a sample comprising mRNA present in the prostate cancer cells exposed to the test compound; and c) determining that the test compound alters the expression of KIAA0101 mRNA when the level of KIAA0101 mRNA measured in step a) differs from the level of KIAA0101 mRNA measured in step b); wherein the KIAA0101 mRNA is selected from the group consisting of: i) an mRNA comprising the complete complement of the nucleotide sequence of SEQ ID NO:3 wherein each T is replaced by a U; and ii) an mRNA encoding the amino acid sequence of SEQ ID NO:2.