Patent ID: 7439020
Filing Date: 2008-10-21
Classification: C12Q

Abstract:
1. A method of determining a pre-disposition of an individual infected with hepatitis B virus (HBV) to develop hepatocellular carcinoma (HCC), the method comprising: determining nucleotides in the genome of an HBV isolated from the individual at positions corresponding to nucleotides 31, 53, 1165, 1499, 1899, 2170, 2441, 2525, and 2712 of SEQ ID NO:1; and determining that the HBV genome does have 31C, 53C, 1165T, 1499G, 1899A, 2170C, 2170G, 2441C, 2525C, 2712C, 2712A, and/or 2712G, wherein if the HBV has one of the nucleotides, the individual has a pre-disposition to develop HCC.