Patent ID: 6586191
Filing Date: 2003-07-01
Classification: A01K,A61K,A61P,C07K,C12P

Abstract:
A process for identifying a chemical compound which specifically binds to a human galanin receptor (GALR2) which comprises contacting cells transfected with DNA encoding and expressing on their cell surface the human galanin receptor (GALR2), wherein such cells prior to being transfected with such DNA do not express the human galanin receptor (GALR2), with the compound under conditions suitable for binding, and detecting specific binding of the chemical compound to the human galanin receptor (GALR2), wherein the human galanin receptor (GALR2) has an amino acid sequence identical to that (a) shown in SEQ ID NO: 30, (b) expressed by COS-7 cells transfected with plasmid BO29 (ATCC Accession No. 97735) or (c) expressed by COS-7 cells transfected with plasmid BO39 (ATCC Accession No. 97851).