Patent ID: 8206903
Filing Date: 2012-06-26
Classification: C12M,C12N,G01N

Abstract:
1. A method of monitoring a cellular response in real time, comprising: a. monitoring at least one impedance measurement prior to transfecting a cell or cell population; b. determining said cell or cell population is to be transfected if said at least one impedance measurement prior to transfecting said cell or cell population is within a predetermined range; c. transfecting said cell or cell population with a molecule if determined to be transfected, wherein said cell or cell population is transfected using a method selected from the group consisting of a chemical transfection method, electroporation and a viral transfection method, further wherein said molecule is capable of affecting a cellular function selected from the group consisting of cell proliferation, cell adhesion and cell spreading; and d. monitoring impedance of said cell or said cell population when said cell or said cell population is attached to an impedance-monitoring electrode.