Patent ID: 7658946
Filing Date: 2010-02-09
Classification: B01J,B82Y,C07B,C07F,C07H,C08G,C40B,G01N

Abstract:
1. A biochip or dendrichip, characterized in that it consists of a solid support comprising at least one surface functionalized with phosphorus-containing dendrimers chosen from those consisting of: a central layer in the form of a central core P n intermediate layers, which may be identical or different, each of said intermediate layers consisting of P in which: L is an oxygen, phosphorus, sulfur or nitrogen atom, M represents one of the following groups: R n is an integer between 1 and 11, E is an oxygen, sulfur or nitrogen atom, said nitrogen atom possibly being linked to an alkyl, alkoxy or aryl group, all these groups possibly incorporating phosphorus, oxygen, nitrogen or sulfur atoms or halogens, an external layer consisting of units P in which: W represents one of the following groups: alkyl, alkoxy, aryl, all these groups possibly comprising phosphorus, oxygen, nitrogen or sulfur atoms or halogens, X represents an aldehyde, thiol, amine, epoxide, carboxylic acid, alcohol or phenol group, to which are covalently bound molecules of interest.