Patent ID: 7355033
Filing Date: 2008-04-08
Classification: C07K,C12N,C12Q

Abstract:
1. A DNA molecule comprising a DNA sequence encoding a mRNA of a lineage I WNV genome wherein the nucleotide sequence is as set forth in SEQ ID NO.2, said DNA sequence having a 5′ and a 3′ end, said DNA molecule adapted to report the transcription of said DNA sequence, said DNA molecule comprising: (a) a deletion in said DNA sequence corresponding to one or more structural genes of said lineage I WNV genome; (b) a promoter at said 5′ end of said DNA sequence; (c) a nucleotide sequence encoding a reporter at said 3′ end of the DNA sequence; wherein said promoter is operably linked and adapted to control the transcription of said DNA sequence and said nucleotide sequence encoding said reporter.