Patent ID: 8642347
Filing Date: 2014-02-04
Classification: C07K,G01N

Abstract:
1. A method of diagnostically evaluating a woman for ovarian cancer, said method comprising: (a) obtaining a test urine sample from said woman; (b) assaying said test urine sample to determine the amount or concentration of at least one CA125 peptide selected from the group consisting of: (1) a CA125 peptide consisting of the amino acid sequence of SEQ ID NO: 1; (2) a CA125 peptide consisting of the amino acid sequence of SEQ ID NO: 2; (3) a CA125 peptide consisting of the amino acid sequence of SEQ ID NO: 3; (c) comparing the results obtained from the assay of step (b) with results from an assay of one or more control urine samples acquired from women not afflicted with ovarian cancer; and (d) concluding that said woman is positive for ovarian cancer if the amount or concentration of said at least one CA125 peptide is higher in said test urine sample than in said one or more control urine samples.