Patent ID: 7875587
Filing Date: 2011-01-25
Classification: A61K,C07K,Y10T

Abstract:
1. A method of treating insulin resistance, the method comprising administering to a mammal in need of such treatment a therapeutically effective amount of a GIP receptor antagonist, the GIP receptor antagonist comprising a peptide analogue of GIP (1-42) (SEQ ID NO: 1), the peptide analogue selected from the group consisting of (i) at least 12 amino acid residues from the N-terminal end of GIP (3-42) wherein the amino acids at positions 1 and 2 of GIP (1-42) are absent; and (ii) at least 12 amino acid residues from the N-terminal end of GIP (1-42) and having an amino acid substitution at Glu