Patent ID: 7527937
Filing Date: 2009-05-05
Classification: A61P,G01N

Abstract:
1. A method for identifying a compound that inhibits or promotes a function of a protein comprising the amino acid sequence represented by SEQ ID NOs: 2, 16, 18, 20, or 22, said method comprising: allowing a transformant in which a recombinant vector containing a DNA that encodes the protein comprising the amino acid sequence represented by SEQ ID NOs: 2, 16, 18, 20 or 22 has been introduced or the HA-ph01207#10-6 cell line deposited under the Accession Number: FERM BP-10101 to co-exist with a test compound under conditions that enable interaction of the transformant or the cell line with the test compound; introducing a system to measure a function of the protein that is expressed on a cell membrane of the transformant or the cell line; and determining whether or not the test compound inhibits or promotes the function of the protein by detecting the existence or non-existence of, or a change in, the function of the protein, wherein the function of the protein is produced by addition of a peptide or peptides selected from a) cholecystokinin octapeptide sulfated form (CCK-8S) consisting of the amino acid sequence represented by SEQ ID NO: 14 or b) a peptide comprising an addition of one amino acid in the amino acid sequence of CCK-8S and having an effect equivalent to CCK-8S on the function of said protein.