Patent ID: 6689914
Filing Date: 2004-02-10
Classification: C07C

Abstract:
A process for the preparation of amines of the formula (I):R1R2CHâ€”N R3R4â€ƒâ€ƒ(I) in which R1, R2, R3 and R4, independently of one another, are hydrogen, straight-chain or branched C1-C12-alkyl, C3-C12-cycloalkyl, C6-C10-aryl or C7-C11-aralkyl,by catalytic, reductive amination of mixtures comprising carbonyl compounds of the formula (II) and/or alcohols of the formula (III):R1â€”C(&boxH;O)â€”R2â€ƒâ€ƒ(II) R1â€”CH(OH)â€”R2â€ƒâ€ƒ(III) which also comprise at least 50 ppm, based on the mixtures, of halogen, with nitrogen compounds of the formula (IV):H N R3 R4â€ƒâ€ƒ(IV) with the abovementioned meanings for R1 to R4, in the presence of Co- and/or Ni-containing catalysts, which comprises carrying out the reductive amination additionally in the presence of solid acidic cocatalysts.