Patent ID: 7145008
Filing Date: 2006-12-05
Classification: A61P,C07D

Abstract:
1. A compound of the formula 1 or a pharmaceutically acceptable salt thereof, wherein Ar is selected from: and ring B is wherein m is an integer from 0–2, Ra is a substituent attached to any aromatic carbon capable of substitution, wherein Ra is selected from the group consisting of hydrogen, halogen, hydroxy, —CF Rb is a substituent selected from the group consisting of hydrogen, —(C each Rc independently represents a substituent selected from the group consisting of hydrogen, halogen, hydroxy, —CF or two Rc substituents may be taken together with the carbon atom to which they are attached to form a cyclic group selected from the group consisting of —(C with the proviso that Ar cannot be wherein n is an integer from 1 to 3; each R each R R R (a) hydrogen; (b) —(C (c) —(C (d) —(C and wherein each R R R R R R R R R