Patent ID: 6290943
Filing Date: 2001-09-18
Classification: A61K,A61Q

Abstract:
A W.sub.1 -O-W.sub.2 multiple emulsion comprising:(1) about 1% to 99% by wt. of the composition of a W.sub.1 /O emulsion comprising;(a) about 1% to 99% of said emulsion of an internal aqueous phase comprising (i) water; (ii) 0.01 to 30% by wt. emulsion solute; and (iii) 0-30% optional surfactant;(b) about 0.5% to about 99% of the emulsion of an oil phase surrounding said internal aqueous phase wherein said oil is selected from the group consisting of volatile hydrocarbon, nonvolatile hydrocarbons, nonvolatile silicones and mixtures thereof;(c) about 0.1 to about 20% by wt. emulsion of a surfactant emulsifier selected from the group consisting of a silicon-free surfactant or surfactant blend having an HLB value of about 10 or less, an oil soluble silicon based surfactant, an oil-soluble polymeric surfactant and mixture thereof; and(d) an optional and topically effective amount of a first topically active compound, which may be found in either the aqueous phase (a), oil phase (b) or both; and(2) about 1 to 99% by wt. of an external isotropic aqueous phase W.sub.2 comprising:(a) 2 to 80% by wt. aqueous phase of a surfactant phase which comprises a non-amido anionic or nonionic or mixture of two in combination with at least one amphoteric;wherein the ratio of anionic and/or nonionic to amphoteric is 100:1 to 1:100(b) 0 to 60% by wt. of external phase of a second topically active compound; and(c) optional solute.