Patent ID: 8845507
Filing Date: 2014-09-30
Classification: A61K,A61P,B82Y,Y10S

Abstract:
1. A method for altering, destroying or eliminating target cells in an animal by i) administering a nanoparticle or nanoparticle aggregate or a composition comprising the nanoparticle or nanoparticle aggregate, wherein the nanoparticle or nanoparticle aggregate consists of a metal oxide coated with a biocompatible coating, wherein the density of the nanoparticle or the density of the nanoparticle aggregate is at least 7 g/cm 3 , and the nanoparticle or nanoparticle aggregate is covered with a biocompatible coating providing the nanoparticle or the nanoparticle aggregate stability between pH 6.5 and 7.5 in a physiological fluid, and ii) exposing said animal to ionizing radiations.