Patent ID: 9073965
Filing Date: 2015-07-07
Classification: A61K,C07K

Abstract:
1. A compound of Formula I: wherein SEQ ID NO:1 is Xaa1-Ile-Pro-Xaa2-Leu-Tyr-Xaa3-Phe-Ala-Xaa4-Xaa5, wherein: (a) Xaa1 is Asn or a non-natural amino acid; (b) Xaa2 is Gly or a non-natural amino acid; (c) Xaa3 is Tyr or a non-natural amino acid; (d) Xaa4 is Tyr or a non-natural amino acid; (e) Xaa5 is no amino acid, β-Ala or β-AlaNH provided, at least one of Xaa1, Xaa2, Xaa3, or Xaa4 is a non-natural amino acid; X is an optionally present Z is an optionally present M1 is an optionally present single bond or a linking group; and M2 is an optionally present single bond or a linking group; wherein, when the compound of formula I comprises a C-terminal amino acid, said C-terminal amino acid is optionally amidated; or a salt thereof.