Patent ID: 6232290
Filing Date: 2001-05-15
Classification: A61K,A61P,C07K

Abstract:
A polypeptide compound of following the general formula: ##STR607##whereinR.sup.1 is hydrogen;arylamino (lower) alkanoyl which may have one or more substituent(s);aroyl substituted with heterocyclic group which may have one or more substituent(s);aroyl substituted with aryl having higher alkyl;aroyl substituted with aryl having lower alkyl;aryl (C.sub.2 -C.sub.6) alkanoyl substituted with aryl having lower alkyl;lower alkanoyl substituted with unsaturated condensed heterocyclic group which may have one or more substituent(s);lower alkanoyl substituted with pyridyl which may have one or more substituent(s);heptylnaphthoyl;hexylnaphthoyl;aroyl substituted with heterocyclic carbamoyl which may have one or more substituent(s);lower alkanoyl substituted with cyclo (lower) alkyl which may have one or more substituent(s);lower alkanoyl substituted with thienyl having heterocyclic group which may have one or more substituent(s); orlower alkanoyl substituted with heterocyclic group which may have one or more substituent(s),R.sup.2 is hydrogen or hydroxy,R.sup.3 is hydroxy, hydroxysulfonyloxy or lower alkoxy, andR.sup.4 is hydroxy or lower alkoxy, or a salt thereof.