Patent ID: 6313161
Filing Date: 2001-11-06
Classification: C07J

Abstract:
A method of treating benign prostatic hyperplasia which comprises administrating to a patient in need thereof an effective aromatase-inhibiting amount of a compound of the formula: ##STR16##wherein: ##STR17##represents a single or double bond, with the proviso that the compound must contain at least one double bond,A is O, S, SO, or SO.sub.2,R is H, .dbd.CH.sub.2, .dbd.O, or --OH,R.sup.1 is H or C.sub.1-4 alkyl,R.sup.2 is .dbd.O, --OH, or --O--(C.sub.1-4 alkanoyl),X is .dbd.O, .dbd.CH.sub.2, --OH, or --O--(C.sub.1-4 alkanoyl), andY is H, --OH, or --O--(C.sub.1-4 alkanoyl), and when Y=H, --H, or --O--(C.sub.1-4 alkanoyl), X may not include --OH, and R may not include .dbd.O or --OH.