Patent ID: 8043610
Filing Date: 2011-10-25
Classification: A61K,C12N

Abstract:
1. A method of introducing foreign matter into a cell or a living organism, which method comprises: (1) rehydrating a freeze-dried composition containing an inactivated virus envelope having membrane fusion activity with a mixture comprising the foreign matter and water, wherein the inactivated virus envelope has membrane fusion activity, and at least one stabilizer selected from the group consisting of a protein hydrolysate, leucine, an L-orginine-acid and a polysaccharide, which is prepared by a process comprising (I) mixing a suspension of the inactivated virus envelope having membrane fusion activity and the stabilizer wherein the mixture has a total salt concentration of at most 3 mM; and (II) freeze-drying the mixture obtained in (1); and (2) bringing the composition obtained in (1) into contact with the cell or the living organism.