Patent ID: 6700007
Filing Date: 2004-03-02
Classification: C07C,C07D,C07F,Y02P

Abstract:
In a process for preparing alkoxyamines of formula: from nitroxides of formula: in which formulae the groups Y1 to Y6, which may be identical or different, represent a hydrogen atom, a linear or branched alkyl radical containing a number of carbon atoms ranging from 1 to 10 inclusive, a cycloalkyl radical containing a number of carbon atoms ranging from 3 to 20, a halogen atom, a cyano radical, a phenyl radical, a hydroxyalkyl radical containing a number of carbon atoms ranging from 1 to 4 inclusive, a dialkoxyphosphonyl or diphenoxyphosphonyl radical, an alkoxycarbonyl or alkoxycarbonylalkyl radical, or alternatively 2 or more of the groups Y1 to Y6 can be linked with the carbon atom which bears them to form cyclic structures, which optionally comprise one or more exocyclic functions chosen from: HOâ€”., CH3C(O)â€”, alkyl-C(O)Oâ€” or a linear or branched alkyl radical containing a number of carbon atoms ranging from 1 to 30 inclusive, CH3Oâ€”, H2Nâ€”CH3C(O)(NHâ€”, (CH3)2Nâ€”; or alternatively can comprise 1 or more exocyclic or endocyclic hetero atoms chosen from O or N;Z is a residue of formula â€ƒin which W1, W2 and W3, which may be identical or different, represent a hydrogen atom, a linear or branched alkyl radical containing a number of carbon atoms ranging from 1 to 10 inclusive, a phenyl radical, a benzyl radical, a cyano radical, a cycloalkyl radical containing a number of carbon atoms ranging from 3 to 12 inclusive; a radical â€”(CH2)rC(O)OW4 in which W4 represents a linear or branched alkyl containing a number of carbon atoms ranging from 1 to 6 inclusive, r=0 to 6; X represents a chlorine, bromine or iodine atom, said process comprising reacting said nitroxide (II) with a halocarbon compound ZX, in the presence of an organometallic system MAn(L)y (III) in which: M comprises Mn, a transition metal with an oxidation state n such that it can participate in a redox reaction with a transferable atom or group, A represents a halogen atom, a carboxylate group or a triflate group, L represents a ligand for the metal M, y is equal to 1, 2 or 3, n is equal to 1, or 2, according to the scheme: the improvement comprising conducting said process in a biphasic medium comprising at least one ionic liquid and an organic solvent which is immiscible with said ionic liquid.