Patent ID: 6573364
Filing Date: 2003-06-03
Classification: A61K,A61P,C07K,C12N,G01N

Abstract:
A purified complex of the Hermansky-Pudlak Syndrome (â€œHPSâ€ ) protein of SEQ ID NO: 6 and an Hermansky-Pudlak Syndrome protein-Interacting protein (â€œHPS-IPâ€ ) protein, wherein said HPS-IP protein is selected from the group consisting of a 14-3-3 eta polypeptide comprising the amino acid sequence of SEQ ID NO: 8, a Hrs polypeptide comprising the amino acid sequence of SEQ ID NO: 10, a BMK1 alpha kinase polypeptide comprising the amino acid sequence of SEQ ID NO: 12, a CDK2 polypeptide comprising the amino acid sequence of SEQ ID NO: 14, a Nuclear factor NF90 polypeptide comprising the amino acid sequence of SEQ ID NO: 16, an Atrophin-1 polypeptide comprising the amino acid sequence of SEQ ID NO: 18, a DGS-I polypeptide comprising an amino acid sequence encoded by SEQ ID NO: 19, an HPIP1 polypeptide comprising the amino acid sequence of SEQ ID NO: 2 and a human HN1 homolog protein comprising the amino acid sequence of SEQ ID NO: 4.