Patent ID: 7964591
Filing Date: 2011-06-21
Classification: A61K,A61P,C07D

Abstract:
1. A method of treating a skin disorder mediated by stearoyl-CoA desaturase (SCD) in a mammal, wherein the method comprises administering to the mammal in need thereof a therapeutically effective amount of a compound of formula (I): wherein: x and y are each independently 1, 2 or 3, provided that x and y are not both 1; W is —C(O)N(R V is —C(O)—, —C(S)—, or —C(R each R R R R R R or R one of R R each R a stereoisomer, enantiomer or tautomer thereof, a pharmaceutically acceptable salt thereof, or a pharmaceutical composition thereof, wherein the skin disorder is selected from the group consisting of acne, rosacea, seborrheic skin, and any combination of these.