Patent ID: 6423822
Filing Date: 2002-07-23
Classification: A61K,C07K

Abstract:
An isolated polypeptide comprising amino acids at least 85% identical to amino acids selected from the group consisting of:(a) amino acids about 1 to about 1261 of SEQ ID NO:2; (b) amino acids about 46 to about 1261 of SEQ ID NO:2; (c) amino acids about 165 to about 1261 of SEQ ID NO:2; (d) amino acids about 165 to about 585 of SEQ ID NO:2; (e) amino acids about 165 to about 698 of SEQ ID NO:2; (f) amino acids about 165 to about 819 of SEQ ID NO:2; and (g) the amino acids of any of (a) through (f) in which amino acids 175 to 186 are deleted, wherein said polypeptide binds to and negatively regulates CIF150/hTAFII150.