Patent ID: 6465687
Filing Date: 2002-10-15
Classification: A61P,C07C,C07F

Abstract:
A compound having the formula whereinR1 is alkyl of 1 to 4 carbons or cycloalkyl of 3 to 7 carbons; R2 and R3 are the same or different and are hydrogen, fluorine, chlorine, bromine, alkyl of 1 to 3 carbons or cycloalkyl of 3 to 5 carbons, at least one of R2 and R3 being other than hydrogen; n is an integer from 0 to 4; R4 is an aliphatic hydrocarbon, an aromatic hydrocarbon, hydroxy, halogen, cyano, â€”P(OH)2 group or ester thereof, an alkenyl carboxylic acid or ester thereof, or a pharmaceutically acceptable salt thereof, and all stereoisomers thereof; or, provided that when n is 0 or 1, then R4 is a COOH group or ester thereof, or a pharmaceutically acceptable salt thereof, and all stereoisomers thereof.