Patent ID: 6124430
Filing Date: 2000-09-26
Classification: C07K,Y10S

Abstract:
A peptide fragment of hBNP, useful as a reagent in an immunoassay for quantifying hBNP, the formula of which isX.sup.1 -V-Q-G-S-G-C-F-G-R-X.sup.2 (SEQ ID NO:2),wherein X.sup.1 is selected from the group consisting ofhydrogenM-,K-M-,P-K-M- andS-P-K-M- (positions 1-4 of SEQ ID NO:1)and X.sup.2 is selected from the group consisting ofhydroxyl,-K,-K-M,-K-M-D and-K-M-D-R (positions 14-17 of SEQ ID NO:1),or the retro-inverso isomers, partially modified retro-inverso-isomers or D-amino isomers thereof.