Patent ID: 6107307
Filing Date: 2000-08-22
Classification: A61P,C07D

Abstract:
A compound of Formula I ##STR9## where A-B is --C.dbd.CH--, or --CH--CH.sub.2 --;R is H, or C.sub.1 -C.sub.4 ; andHET is a bicyclic heteroaryl group selected from indol-2-yl, indol-3-yl, benzothien-2-yl, benzothien-3-yl, benzofur-2-yl, benzofur-3-yl, benzothiazol-2-yl, benzoxazol-2-yl, quinolin-2-yl quinolin-3-yl, quinolin-4-yl, isoquinolin-1-yl, isoquinolin-3-yl, isoquinolin-4-yl, and quinoxalin-2-yl, each substituted on the phenyl ring with one or two substitutents independently selected from the group consisting of halo, C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.6 cycloalkyl, C.sub.1 -C.sub.4 alkoxy, cyano, nitro, carboxamido, trifluoromethyl, or hydroxy; and pharmaceutically acceptable salts thereof.