Patent ID: 7670805
Filing Date: 2010-03-02
Classification: A61K,C07K

Abstract:
1. A method for producing an isolated antibody having an affinity to the N-terminal portion of PTH (1-84), the method comprising the steps: a) administering rat (1-34) PTH peptide to a host animal to induce antibody production against said rat (1-34) PTH peptide in said host animal; b) monitoring antibody titer produced by said administration of said rat (1-34) PTH peptide to said host animal; c) extracting antisera produced in said host animal by said administration of said rat (1-34) PTH peptide; and d) isolating and selecting said antibody from said antisera extracted in step c) by affinity chromatography utilizing a peptide antigen selected from the group consisting of SEQ ID NO. 3 and SEQ ID NO. 4.