Patent ID: 6066678
Filing Date: 2000-05-23
Classification: A61K,A61P,C08F,C08L

Abstract:
The salt of an alkylated and crosslinked polymer comprising the reaction product of:(a) one or more polymers, or salts and copolymers thereof having a repeat unit selected from the group consisting of: ##STR3##(NR--CH.sub.2 CH.sub.2).sub.n ( 2) and(NR--CH.sub.2 CH.sub.2 --NR--CH.sub.2 CH.sub.2 --NR--CH.sub.2 CHOH--CH.sub.2).sub.n ( 3)where n is a positive integer and each R, independently, is H or a C.sub.1 -C.sub.8 alkyl group;(b) at least one aliphatic alkylating agent; and(c) a crosslinking agent, wherein said reaction product has:(i) at least some of the nitrogen atoms in said repeat units unreacted with said alkylating agent;(ii) less than 10 mol % of the nitrogen atoms in said repeat units reacting with said alkylating agent forming quaternary ammonium units; and(iii) a fixed positive charge and one or more counterions.