Patent ID: 7091184
Filing Date: 2006-08-15
Classification: A61K,C07D,C07K

Abstract:
1. A compound of formula (I): wherein R 1 is hydroxy or NHSO 2 R 1A wherein R 1A is (C 1-8 )alkyl, (C 3-7 )cycloalkyl or {(C 1-6 )alkyl-(C 3-7 )cycloalkyl }, which are all optionally substituted from 1 to 3 times with halo, cyano, nitro, O—(C 1-6 )alkyl, amido, amino or phenyl, or R 1A is C 6 or C 10 aryl which is optionally substituted from 1 to 3 times with halo, cyano, nitro, (C 1-6 )alkyl, O—(C 1-6 )alkyl, amido, amino or phenyl; R 2 is t-butyl, —CH 2 —C(CH 3 ) 3 , or —CH 2 -cyclopentyl; R 3 is t-butyl or cyclohexyl and R 4 is cyclobutyl, cyclopentyl, or cyclohexyl; or a pharmaceutically acceptable salt thereof.