Patent ID: 8053543
Filing Date: 2011-11-08
Classification: B01J,C08B

Abstract:
1. A method of producing beads used in the separation of optical isomers, comprising the steps of: modifying some of the hydroxy or amino groups of a polysaccharide having hydroxy or amino groups with molecules of a compound represented by formula (I) where A is a chlorocarbonyl group, a carboxyl group, an isocyanate group, a glycidyl group or a thiocyanate group, X is an alkylene group, which may be branched, having from 1-18 carbon atoms or an arylene group which may have a substituent, Y is an alkoxy group having 1-12 carbon atoms or a halogen group, R is an alkyl group, which may be branched, having 1-18 carbon atoms or an aryl group which may have a substituent and n is an integer of 1-3, to form a polysaccharide derivative; dissolving the polysaccharide derivative in an organic solvent to prepare a polysaccharide derivative solution; and adding the polysaccharide derivative solution to an aqueous solution of a surfactant or proton-donating solvent while stirring the aqueous solution or solvent to cross-link the polysaccharide derivative and forming the beads; wherein a ratio of introduction of the molecules of the compound of formula (I) into the hydroxy or amino groups of the polysaccharide is from 1.0-35%.