Patent ID: 7811606
Filing Date: 2010-10-12
Classification: A61K,A61L,A61P

Abstract:
1. A nasal pharmaceutical formulation comprising an aqueous suspension of a therapeutically effective amount of a drug substance, wherein the therapeutically effective amount of a drug substance comprises about 0.01% to about 1% of beclomethasone, the aqueous suspension has the following suspended solid active drug substance particle size distribution profile: (i) about 10% of the drug substance particles have a particle size of less than 0.3 microns; (ii) about 25% of the drug substance particles have a particle size of less than 0.55 microns; (iii) about 50% of the drug substance particles have a particle size of less than 1.1 microns; (iv) about 75% of the drug substance particles have a particle size of less than 1.8 microns; and (v) about 90% of the drug substance particles have a particle size of less than 2.7 microns; wherein the formulation is suitable for administration to the nasal mucosa of an individual.