Patent ID: 6211210
Filing Date: 2001-04-03
Classification: A61P,C07D

Abstract:
A compound of Formula I ##STR20##or a pharmaceutically acceptable salt thereof wherein:R 1 is selected from the group consisting of:(a) S(O).sub.2 CH.sub.3,(b) S(O).sub.2 NHR.sup.4,(c) S(O).sub.2 NHCOCF.sub.3,(d) S(O)(NH)CH.sub.3,(e) S(O)(NH)NH.sub.2,(f) S(O)(NH)NHCOCF.sub.3,(g) P(O)(CH.sub.3)OH, and(h) P(O)(CH.sub.3)NH.sub.2,R.sup.2 and R.sup.3 are each independently selected from the group consisting of:(a) hydrogen,(b) halo,(c) C.sub.1-6 alkoxy,(d) C.sub.1-6 alkylthio,(e) CN,(f) C.sub.1-3 fluoroalkyl,(g) C.sub.1-6 alkyl,(h) N.sub.3,(i) --CO.sub.2 H,(j) --CO.sub.2 --C.sub.1-4 alkyl,(k) --C(R.sup.5)(R.sup.6)--OH,(l) --C(R.sup.5)(R.sup.6)--O--C.sub.1-4 alkyl, and(m) --C.sub.1-6 alkyl-CO.sub.2 --R.sup.7 ;R.sup.4 is selected from the group consisting of H, C.sub.1-6 alkyl, phenyl and benzyl; andR.sup.5, R.sup.6 and R.sup.7 are each independently selected from the group consisting of:(a) hydrogen, and(b) C.sub.1-6 alkyl.