Patent ID: 8063222
Filing Date: 2011-11-22
Classification: A61P,C07C,C07D

Abstract:
1. A compound represented by structural formula (I): or a pharmaceutically acceptable salt thereof, wherein: X m is 0, 1, 2 or 3; n is 1 or 2; C═Z is C═O, CH R R R R X is a covalent bond, 0, or NR Ar in Formula (I) is selected from: wherein Ar is optionally substituted at any substitutable carbon or nitrogen atom with p independent occurrences of R 6 , wherein: p is 0, 1, 2, or 3; and each occurrence of R 6 is independently halogen, —CN, NO 2 , —R 7 , or —OR 7 , wherein each occurrence of R 7 is independently hydrogen or a substituted or unsubstituted C 1 -C 6 aliphatic group, provided that when R