Patent ID: 6365585
Filing Date: 2002-04-02
Classification: C07D

Abstract:
A compound of formula (III) wherein:Zâ€² is hydroxymethyl, formyl, carboxylic acid in its free form, salified, esterified or amidated, hydroxymethyl whose hydroxyl group is esterified; Aâ€² is aryl, a nitrogen-containing, 4- to 7-membered, unsaturated monocyclic group having carbon atoms and from 0 to 3 additional heteroatoms selected from the group consisting of nitrogen and sulphur, a sulphur-containing, 4- to 7-membered, unsaturated monocyclic group having carbon atoms and optionally from 0 to 3 additional heteroatoms selected from the group consisting of nitrogen and sulphur, or an unsaturated fused bicyclic group having carbon atoms and containing 1 heteroatom which is nitrogen or sulphur and optionally from 0 to 3 additional heteroatoms selected from the group consisting of nitrogen and sulphur, each optionally substituted with one to three groups independently chosen from halogen, lower alkyl, haloalkyl, lower alkoxy, hydroxyl, acetoxy, amino, t-butoxycarbonylamino, cycloalkylcarbonylamino or acetamido, the N-oxide or S-oxide forms; Yâ€² is hydroxyl or lower alkoxy; nâ€² is 0,1 or 2; as the racemic form thereof, or its isomers having a configuration which is determined by the carbon at the 3-position of the diazepinoindol 4-one ring, or its pharmacologically acceptable salts.