Patent ID: 6497872
Filing Date: 2002-12-24
Classification: A01K,A61K,C07K,C12N,C12Y,G01N

Abstract:
A method of transplanting multipotent neural stem cell progeny to a host comprising:(a) obtaining a population of cells derived from mammalian neural tissue containing at least one multipotent CNS neural stem cell, said neural stem cell under suitable culture conditions producing progeny that differentiate into neurons that express neuron specific enolase or neurofilament and glia that express glial fibrillary acidic protein or express galactocerebroside; (b) culturing the neural stem cell in (a) in a culture medium containing one or more growth factors which under suitable culture conditions induces multipotent neural stem cell proliferation; (c) inducing proliferation of said multipotent neural stem cell to produce neural stem cell progeny which includes multipotent neural stem cell progeny cells; and (d) transplanting said multipotent neural stem cell progeny to said host.