Patent ID: 7862833
Filing Date: 2011-01-04
Classification: A61K,A61P

Abstract:
1. A dosage form comprising about 20 to about 200,000 micrograms of an opiate, about 15 to about 60% w/w of an effervescent material, wherein said effervescent material comprises an acid source and a source of a reactive base, and wherein said acid source and said base source are present in said dosage form in stoichiometrically equivalent amounts; about 0.5 to about 25% w/w of a pH adjusting substance, wherein said pH adjusting substance is in addition to the components of said effervescent material, a filler, wherein said filler is mannitol; and a starch glycolate, wherein said dosage form is configured for the delivery of said opiate across the oral mucosa as a consequence of buccal, gingival or sublingual administration.