Patent ID: 9056052
Filing Date: 2015-06-16
Classification: A61K,A61P

Abstract:
1. A solid oral controlled-release dosage form of hydrocodone, the dosage form comprising a matrix comprising hydrocodone or a pharmaceutically acceptable salt thereof, a controlled release material and hydroxypropylcellulose or hydroxypropylmethylcellulose, such that the dosage form provides a ratio of a plasma concentration of hydrocodone at the end of a dosing interval to a maximum plasma concentration of hydrocodone during the dosing interval of about 0.55 to about 1 and an effective pain relief over a period of time of about 12 hours or longer after administration to a human patient, wherein the dosage form is a compressed tablet, the amount of hydrocodone in the dosage form is from about 0.5 mg to about 1250 mg, and the hydrocodone or pharmaceutically acceptable salt thereof is the only active agent in the dosage form.