Patent ID: 6187760
Filing Date: 2001-02-13
Classification: A61K,B82Y,C07F,C12N

Abstract:
A cationic phospholipid having the structure: ##STR12##whereinR.sup.1 and R.sup.2 independently are H or C.sub.1 to about C.sub.24 straight or branched alkyl, alkenyl, or alkynyl chains optionally substituted with a dansyl, NBD, DPH, carbocyclic aromatic, or heterocyclic moiety,R.sup.3 is hydrogen or methyl,R.sup.4 is a C.sub.1 to about C.sub.24 straight or branched alkyl, alkenyl, or alkynyl chain optionally substituted with a dansyl, NBD, DPH, carbocyclic aromatic, or heterocyclic moiety, or R.sup.4 is a C.sub.1 to about C.sub.6 straight or branched chain ester, aldehyde, ketone, ether, haloalkyl, azidoalkyl, or tetraalkylanmronium,n is 0, 1, 2, or 3,s is 0 or 1, andt is 0 or 1,provided that R.sup.1 and R.sup.2 are not both H and that when R.sup.1 is H, s is 0, and that when R.sup.2 is H, t is 0.