Patent ID: 8431718
Filing Date: 2013-04-30
Classification: C07D

Abstract:
1. A process for preparing a compound of formula (I) in which R (1) chlorinating a compound of formula (II) (2a-i) fluorinating the compound of formula (III) in the presence of a fluorinating agent of formula (IV), in which M (2a-ii) hydrolyzing a compound of the formula (V) to give a compound of formula (VIa); and (2a-iii) subsequent halogenation to give the compound of the formula (I), in which X is fluorine or chlorine; or (2b-i) hydrolyzing a compound of formula (III) to give a compound of formula (VIb); (2b-ii) subsequent halogenation of the a compound of formula (VIb) to give a compound of formula (VII); and (2b-iii) fluorinating a compound of formula (VII) in the presence of a fluorinating agent of the formula (IV), to give a compound of formula (I), in which X is fluorine