Patent ID: 6319224
Filing Date: 2001-11-20
Classification: A61M

Abstract:
A method for performing intradermal injection of liquid injectables into humans, comprising:fitting, adjacent an injection orifice of a needle-free injector, the proximal end of a substantially cylindrical intradermal adapter having a proximal and distal end and an internal abutment against which the injector is disposed to provide a fixed spacing of from approximately 0.76 to 1.0 inches from the injection orifice to the distal end of the adapter, the distal end having an inner diameter of from 0.50 to 0.70 inches;selecting the needle-free injector having the injection orifice of from 0.004 to 0.005 inches;holding the distal end of the intradermal adapter against the skin of the patient; andusing the needle-free injector to inject a liquid injectable in a volume of 0.3 ml or less into the intradermal region at an initial peak pressure of from 3900 to 4300 psi, and then permitting the injection pressure to decay to a level of about 2300 to 3800 psi, after which time the pressure is abruptly cut off, terminating the injection;wherein, following a single quick drop and rebound in pressure following the initial peak pressure, there is no more than plus or minus 100 psi variation from the pressure curve of the injection.