Patent ID: 8536223
Filing Date: 2013-09-17
Classification: A61K,A61P,C07C

Abstract:
1. A topical pharmaceutical composition comprising: a polyunsaturated fatty acid (PUFA) derivative of formula (I), or a pharmaceutically acceptable salt thereof, wherein -Alk- is —CH(OR R R R R and wherein said alkyl, alkenyl, alkynyl and aliphatic groups are the same or different and are each unsubstituted or substituted with 1, 2 or 3 unsubstituted substituents which are the same or different and are selected from halogen atoms and C said aryl, heteroaryl, carbocyclyl and heterocyclyl groups are the same or different and are each unsubstituted or substituted by 1, 2, 3 or 4 unsubstituted substituents which are the same or different and are selected from halogen atoms, and cyano, nitro, C and wherein the PUFA derivative is in the form of a racemate, a stereoisomer or a mixture of stereoisomers; at least one preservative and at least one pharmaceutical excipient; and wherein the topical pharmaceutical composition is substantially free of arachidonic acid and glucocorticoids.