Patent ID: 8728411
Filing Date: 2014-05-20
Classification: B01L,G01N

Abstract:
1. A method of isolating a fraction in a biological sample, the method comprising steps of: providing the biological sample including a fraction-bound solid phase substrate and biological material in an input well, the input well being partially defined by a lower surface lying in a first plane; positioning a force in proximity to the input well such that the force extends along a second plane, the second plane being generally parallel to the first plane and intersecting the input well; capturing the fraction-bound solid phase substrate with the force so as to maintain the fraction-bound solid phase substrate at a location above the lower surface of the input well; allowing the biological material to settle towards the lower surface of the input well; and drawing the fraction-bound solid phase substrate into a fluid in a second well through an interface between the biological sample and the fluid with the force travelling along an axis vertically spaced above the first plane, the interface between the biological sample and the fluid having a surface tension for retaining the biological sample in the input well and the fluid in the second well.