Patent ID: 6451829
Filing Date: 2002-09-17
Classification: A61K,A61P

Abstract:
A pharmaceutical composition for treating or preventing an allergic reaction associated with increased IgE levels in a mammal comprising one or more of the following compounds: wherein X and Y are selected independently from the group consisting of alkyl, alkoxy, aryl, substituted aryl, heteroaryl, substituted heteroaryl, hydroxy, halogen, NO2, CF3, OCF3, NH2, NHR3, NR3R4, and CN; wherein Z is selected from the group consisting of O, S, NH, and Nâ€”R'; wherein R' is further selected from the group consisting of H, alkyl, aminoalkyl, and dialkylaminoalkyl; wherein R is selected from the group consisting of H, alkyl, halogen, alkoxy, CF3 and OCF3; and R1 and R2 are independently selected from the group consisting of H, alkyl, aminoalkyl, dialkylaminoalkyl, hydroxyalkyl, alkoxyalkyl, cycloalkyl, oxacycloalkyl, and thiocycloalkyl.