Patent ID: 6432659
Filing Date: 2002-08-13
Classification: A61P,C12N,Y10S

Abstract:
A method for screening for modulators of AL353662, the method comprising the steps of:(i) providing biologically active AL353662, which has the following properties: (i) activity including microtubule stimulated ATPase activity; and (ii) sequence that has greater than 90% amino acid sequence identity to AL353662 of SEQ ID NO:2 as measured using a sequence comparison algorithm; (ii) contacting biologically active AL353662 with a candidate agent in a test and control concentration; and (iii) assaying for the level of AL353662 activity, wherein the AL353662 activity is selected from the group consisting of binding activity or ATPase activity, and wherein a change in activity between the test and control concentration indicates a modulator.