Patent ID: 8242150
Filing Date: 2012-08-14
Classification: A61P,C07D

Abstract:
1. A compound of formula I: or a pharmaceutically acceptable salt or hydrate thereof; wherein: W completes an imidazole, triazole or pyrazole ring; R Y1 and Y2 each independently represents N or CR R each R or R m is 0 or an integer in the range 1-6; or —(CR X is selected from H, R R (a) C (b) phenyl which optionally forms part of a polycyclic system containing up to 3 additional rings, each of which independently comprises 5, 6 or 7 members and is independently carbocyclic or heterocyclic; (c) 4-, 5-, 6- or 7-membered heterocyclic which optionally forms part of a polycyclic system containing up to 3 additional rings, each of which independently comprises 5, 6 or 7 members and is independently carbocyclic or heterocyclic; where the term “polycyclic system” at each occurrence thereof refers to a system of fused rings, or a system of rings linked by covalent bonds, or any combination of fused and covalently-linked rings; the group represented by R R R or R R with the proviso that if m is 0 or —(CR