Patent ID: 6552016
Filing Date: 2003-04-22
Classification: A61K,C07K

Abstract:
A pharmaceutical preparation comprising a sterile pharmaceutical excipient and a compound represented by the general formula (V): wherein, as valence permits,Y is O or S; Zâ€² is SO2, â€”(C&boxH;S)â€”, â€”(C&boxH;O)â€”, â€”(C&boxH;NH)â€”, or SO; q and r represent, independently for each occurrence, an integer from 0 to 2; V is absent or represents O, S, or NR8; G is absent or represents â€”C(&boxH;O)â€” or â€”SO2â€”; J, independently for each occurrence, represents H or substituted or unsubstituted lower alkyl or alkylene attached to NC(&boxH;Y), such that both occurrences of N adjacent to J are linked through at least one occurrence of J, and R9, independently for each occurrence, is absent or represents H or lower alkyl, or two occurrences of J or one occurrence of J taken together with one occurrence of R9, forms a ring of from 5 to 8 members, which ring includes one or both occurrences of N; R5 represents substituted or unsubstituted alkyl (branched or unbranched), alkenyl (branched or unbranched), alkynyl (branched or unbranched), cycloalkyl, or cycloalkylalkyl; R6 represents substituted or unsubstituted aryl, aralkyl, heteroaryl, heteroaralkyl, heterocyclyl, heterocyclylalkyl, cycloalkyl, or cycloalkylalkyl; and R7 represents substituted or unsubstituted aryl, aralkyl, heteroaryl, or heteroaralkyl.