Patent ID: 6221111
Filing Date: 2001-04-24
Classification: A61F,A61L

Abstract:
A bioactive surface layer of a thickness between 0.01 .mu. and 5 mm for a metal bone implant, the surface layer being disposed on a substrate and containing calcium compounds (CaX) selected from the group consisting of: calcium phosphate (CaP), calcium apatites (CaAp), and calcium carbonate (CaCO.sub.3), the sum of these three substances present in particulate form as (CaX) being defined by the equation:100% (CaX)=.SIGMA.[x % (CaP)+y % (CaAp)+z % (CaCO.sub.3)]wherein x+y+z=100 and 0.ltoreq.x.ltoreq.100; 0.ltoreq.y.ltoreq.100; 0.ltoreq.z.ltoreq.100; andthe dimensions of the CaX particles being between 2 nm and 4 mm, wherein the surface layer additionally contains amorphous or crystalline metal oxide (MeO) except for aluminum oxide and wherein molar ratio CaX/MeO in the surface layer selectively increases from a bottom adjacent the substrate toward a top remote from said substrate.