Patent ID: 6133274
Filing Date: 2000-10-17
Classification: A61K

Abstract:
A compound having the formula:(R)j-(CORE MOIETY),including resolved enantiomers, diastereomers, hydrates, salts, solvates and mixtures thereof, wherein j is an integer from one to three, the core moiety is a xanthinyl or xanthinyl derivative, R is selected from the group consisting of hydrogen, halogen, hydroxyl, amino, substituted or unsubstituted benzyl, C.sub.1-6 alkyl or C.sub.1-6 alkenyl, and at least one R has the formula I: ##STR88## wherein n is an integer from seven to twenty, at least one of X or Y is --OH, another of X or Y, which is not --OH, being selected from the group consisting of hydrogen, CH.sub.3 --, CH.sub.3 --CH.sub.2 --, CH.sub.3 --(CH.sub.2).sub.2 --,and (CH.sub.3).sub.2 --CH.sub.2 --, and each W.sub.1, W.sub.2, and W.sub.3 is independently selected from the group consisting of hydrogen, CH.sub.3 --, CH.sub.3 --CH.sub.2 --, CH.sub.3 --(CH.sub.2).sub.2 --, and (CH.sub.3).sub.2 --CH.sub.2 --, said X, Y, W.sub.1, W.sub.2, or W.sub.3 alkyl groups being unsubstituted or substituted by an hydroxyl, halo or dimethylamino group.