Patent ID: 8183206
Filing Date: 2012-05-22
Classification: A61K,A61P,C07D

Abstract:
1. A method of treating an ischemic disease selected from cerebral infarction, stroke, and impairment of brain function due to cerebral infarction or stroke in a patient comprising parenterally administering to the patient in need thereof and having an ischemic disease selected from cerebral infarction, stroke, and impairment of brain function due to cerebral infarction or stroke (a) a dose of about 0.6 mg per kg of patient weight of a tissue plasminogen activator, and (b) a dose of 60 mg per day of 3-methyl-1-phenyl-2-pyrazolin-5-one or a pharmaceutically acceptable salt thereof, whereby the ischemic disease is treated in the patient.