Patent ID: 6800755
Filing Date: 2004-10-05
Classification: C07D

Abstract:
An improved process for the preparation cefixime of formula (I) the said process comprising the steps of:i. dissolving the compound of formula (II) â€ƒwherein R represents (C1-C4) alkyl group; in water/water immisible solvent using sodium bicarbonate at a temperature in the range of 0Â° C. to the 35Â° C., ii. hydrolyzing with sodium hydroxide at a temperature in the range of 0Â° C. to 25Â° C. and iii. acidifying the resultant mass to pH 2.3 to 3.0 with dilute acid in the presence or absence of solvent at a temperature in the range of 10Â° C. to 45Â° C., to isolate the compound of formula (I).