Patent ID: 6800639
Filing Date: 2004-10-05
Classification: A61K,A61P

Abstract:
A pharmaceutical combination comprising at least one active compound of formula (I): or a pharmaceutically acceptable salt thereof,wherein B is cytosine or 5-fluorocytosine and R is selected from the group comprising H, monophosphate, diphosphate, triphosphate, carbonyl substituted with a C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C6-10 aryl and wherein each Rc is independently selected from the group comprising H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl and a hydroxy protecting group; and gemcitabine and the ratio of the compound of formula (I) to gemcitabine is 1:250 to 250:1.