Patent ID: 7819856
Filing Date: 2010-10-26
Classification: A61M

Abstract:
1. Apparatus for treating acute myocardial infarction by embedding stem cells, endothelial progenitor cells or mediators of stem cell mobilization, migration and attachment, into an infarcted region of myocardium, comprising: a delivery catheter for injecting a solution containing stem cells into the infarcted region of the myocardium, the delivery system having a proximal end including an inlet port and an injection port, a distal end having an outlet port, and a lumen in fluid communication with the inlet port, the injection port, and the outlet port; a flow control element disposed adjacent to the distal end of the delivery catheter, the flow control element configured to be inserted into the coronary sinus to partially or fully occlude outflow through a patient's coronary sinus; and an arterial line having a proximal end configured to be coupled to the inlet port of the delivery catheter and a distal end including an arterial cannula configured to be placed in a patient's femoral artery, wherein the arterial line and delivery catheter are configured to transmit a positive pressure gradient between the distal end of the arterial line and the distal end of the delivery catheter.