Patent ID: 6822064
Filing Date: 2004-11-23
Classification: C08F

Abstract:
A process for preparation of Polymerizable macromer of molecular weight ranging between 700 Daltons to 1,00,000 Daltons having formula (1) wherein, R is H, CH3, C2H5, C6H5, R1 is H, CH3, C2H5, C6H5 X is in the range of 4 to 10 and value on n is in the range of 2 to 50, Y is N-Acetyl Glucosamine(NAG), mannose, galactose, sialic acid, fructose, ribulose, erytbrolose, xylulose, psicose, sorbose, tagatose, glucopyranose, fructofuranose, deoxyribose, galactosamine, sucrose, lactose, isomaltose, maltose, cellobiose, cellulose and amylase, said process comprising following steps: a) dissolving a Polymerizable monomer-spacer conjugate in an organic solvent, b) adding to the solution of step (a) one or more functional oligomer, c) adding coupling agent to step (b) reaction mixture to dissolve, d) allowing to stand the reaction mixture of step (c) at an ambient temperature for 24 hrs to 48 hrs, e) removing the unreacted coupling agent from step (d) reaction rnixture, and f) precipitating the Polymerizable macromer from step (e) reaction mixture by adding a non solvent.