Patent ID: 8993595
Filing Date: 2015-03-31
Classification: A61K,A61P,C07D

Abstract:
1. A pharmaceutical composition comprising a compound of Formula Ia or Ib: or a single enantiomer, a racemic mixture, a mixture of diastereomers, or an isotopic variant thereof; or a pharmaceutically acceptable salt thereof; and one or more pharmaceutically acceptable carriers; wherein: Q Q U and V are each independently N or CH; with the proviso that at least one of U and V is N; and m is an integer of 0 or 1; and n is an integer of 1 or 2; with the proviso that the sum of m and n is 2 or 3; wherein each alkyl, alkylene, alkenyl, alkenylene, alkynyl, alkynylene, cycloalkyl, cycloalkylene, aryl, aralkyl, heterocyclyl, and heteroaryl is optionally substituted with one or more groups, each independently (a) cyano, halo, or nitro; (b) C wherein each Q is independently of (a) cyano, halo, or nitro; (b) C