Patent ID: 9023345
Filing Date: 2015-05-05
Classification: A23K,A61K,A61P,C12Y

Abstract:
1. A method for decreasing a population of bacteria comprising Clostridium perfringens in the upper gastrointestinal tract of a subject irrespective of coccidiosis challenge, the method comprising administering to the subject a supplement consisting essentially of at least one protease in combination with a diet comprising a protein source that is digestible in the upper gastrointestinal tract and fermentable in the lower gastrointestinal tract of the subject, wherein the population of bacteria comprising Clostridium perfringens is reduced in the upper gastrointestinal tract of the subject, irrespective of coccidiosis challenge, and mortality due to necrotic enteritis is reduced by about 50%, and wherein the protease is a serine protease that is administered in an amount from about 0.005% to about 0.5% by weight of the diet and the subject is poultry.