Patent ID: 6030994
Filing Date: 2000-02-29
Classification: A61P,C07D

Abstract:
A pharmaceutical composition comprising an effective amount of a compound of the formula ##STR13## wherein R and R.sup.1 ' are independently alkyl, aryl, alkenyl or alkynyl;R.sup.2 and R.sup.2 ' are independently hydrogen or alkyl;R.sup.4, R.sup.5, and R.sup.7 each independently are ##STR14## CO.sub.2 R.sup.9, CH.sub.2 OR.sup.10, CHO, CH.sub.2 NR.sup.11 R.sup.12, CON(R.sup.13).sub.2, hydrogen, halogen, cyano, alkyl, hydroxy, alkoxy, aryloxy, haloalkyl, nitro, amino, acylamino, aralkyloxy, monoalkylamino, dialkylamino, alkylthio, alkylsulphinyl or alkylsulphonyl;R.sup.6 is CO.sub.2 R.sup.9 ;R.sup.8 is alkyl, aralkyl or aryl;R.sup.9 is alkyl, aralkyl or aryl;R.sup.10 is hydrogen, alkyl, aralkyl or aryl;R.sup.11 and R.sup.12 are independently hydrogen, alkyl, aryl, aralkyl or acyl;R.sup.13 is hydrogen, alkyl, aryl or aralkyl; andone of X and Y signifies O and the other signifies O, S, (H,OH) or (H,H); or pharmaceutically acceptable salts of acidic compounds of formula I with bases or basic compounds of formula I with acids.