Patent ID: 6106744
Filing Date: 2000-08-22
Classification: C07D,C08K,G02B

Abstract:
A naphthopyran compound represented by the following graphic formula: ##STR13## wherein, (a) R.sub.1 and R.sub.2 together form an oxo group or R.sub.1 and R.sub.2 are both hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.3 -C.sub.7 cycloalkyl, allyl, phenyl, mono-substituted phenyl, benzyl or mono-substituted benzyl each of said phenyl and benzyl group substituents being C.sub.1 -C.sub.6 alkyl or C.sub.1 -C.sub.6 alkoxy(b) R.sub.3 is hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.3 -C.sub.7 cycloalkyl, or the group, CH(B)B', wherein B and B' are each selected from the group consisting of:(i) the unsubstituted, mono-, di- and tri-substituted aryl groups, phenyl and naphthyl;(ii) the unsubstituted, mono- and di-substituted hetroaromatic groups pyridyl, furanyl, benzofuran-2-yl, benzofuran-3-yl, thienyl, benzothien-2-yl, benzothien-3-yl, dibenzofuran-4-yl, dibenzothien-4-yl and carbazol-4-yl, each of said aryl and heteroaromatic substituents in (b)(i) and (ii) being selected from the group consisting of aryl, C.sub.1 -C.sub.6 alkoxyaryl, C.sub.1 -C.sub.6 alkylaryl, chloroaryl, fluoroaryl, C.sub.3 -C.sub.7 cycloalkyl, C.sub.3 -C.sub.7 cycloalkyloxy, aryl(C.sub.1 -C.sub.6)alkyl, aryl(C.sub.1 -C.sub.6)alkoxy, aryloxy, C.sub.1 -C.sub.6 alkylaryl(C.sub.1 -C.sub.6)alkyl, C.sub.1 -C.sub.6 alkoxyaryl(C.sub.1 -C.sub.6)alkyl, C.sub.1 -C.sub.6 alkylaryl(C.sub.1 -C.sub.6)alkoxy, C.sub.1 -C.sub.6 alkoxyaryl(C.sub.1 -C.sub.6)alkoxy, amino, mono(C.sub.1 -C.sub.6)alkylamino, di(C.sub.1 -C.sub.6)alkylamino, diarylamino, N-(C.sub.1 -C.sub.6)alkylpiperazino, aziridino, indolino, piperidino, morpholino, thiomorpholino, tetrahydroquinolino, pyrryl, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 chloroalkyl, C.sub.1 -C.sub.6 fluoroalkyl, C.sub.1 -C.sub.6 alkoxy, mono(C.sub.1 -C.sub.6)alkoxy(C.sub.1 -C.sub.4)alkyl, acryloxy, methacryloxy, chloro and fluoro;(iii) the groups represented by the following graphic formulae: ##STR14## wherein E is carbon or oxygen and D is oxygen or substituted nitrogen, provided that when D is substituted nitrogen, E is carbon, said nitrogen substituents being selected from the group consisting of hydrogen, C.sub.1 -C.sub.6 alkyl and C.sub.2 -C.sub.6 acyl; each R.sub.6 is C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy, hydroxy, chloro or fluoro; R.sub.7 and R.sub.8 are each hydrogen or C.sub.1 -C.sub.6 alkyl; and q is the integer 0, 1 or 2;(iv) C.sub.1 -C.sub.6 alkyl, C.sub.1 C.sub.1 -C.sub.6 chloroalkyl, C.sub.1 -C.sub.6 fluoroalkyl, C.sub.1 -C.sub.6 alkoxy(C.sub.1 -C.sub.4)alkyl; and(v) the group represented by the following graphic formula: ##STR15## wherein X is hydrogen or C.sub.1 -C.sub.4 alkyl and Y is selected from the unsubstituted, mono-, and di-substituted members of the group consisting of naphthyl, phenyl, furanyl and thienyl, each of said group substituents being C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, fluoro or chloro;(c) R.sub.4 is hydrogen, C.sub.1 -C.sub.6 alkyl or C.sub.3 -C.sub.7 cycloalkyl; and(d) each R.sub.5 is selected from the group consisting of C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy, chloro and fluoro, and m is the integer 0, 1 or 2.