Patent ID: 8153103
Filing Date: 2012-04-10
Classification: A61K,C08G,G01N

Abstract:
1. A composition comprising a macromolecular carrier, a protecting group, and a coumarin fluorophore, and having the general structure: wherein: X is H, F, Cl, or Br; R R is one substituted or unsubstituted amino acid or a peptide containing up to 20 substituted or unsubstituted amino acids either in D or L configuration any linear or branched alkyl chain up to 20 carbon atoms, oligonucleotide containing amino groups at either 5′ or 3′ terminal, a therapeutic drug, a neurotransmitter, a molecule containing amino or carboxylate groups, or a combination thereof; and the macromolecular carrier is a protein, antibody, dextran amine, polylysine, polyethylene glycol, dendrimer, nanoparticle, quantum dot, a macromolecule containing one or more amino or thiol groups, or a combination thereof.