Patent ID: 8324385
Filing Date: 2012-12-04
Classification: A61P,C07D

Abstract:
1. A compound of formula (I): wherein X is nitrogen; R1 is -phenyl, unsubstituted or mono- or di-substituted independently with halogen, lower alkyl, lower alkanoic acid, lower alkanoyl, lower alkyl ester of lower alkanoic acid, haloloweralkyl, unsubstituted phenyl, halophenyl, alkoxyphenyl or phenyl substituted with haloloweralkyl, R2 is H, halogen or loweralkyl; and R3 is a piperazine ring, said ring being mono- or di-substituted, independently, with halogen, hydroxy, lower alkoxy, phenyl, phenyl substituted with haloloweralkyl, halophenyl, benzoic acid, lower alkyl ester of benzoic acid, lower alkyl oxadiazole, phenyl-pyridine, lower alkanoyl, lower alkanoic acid, lower alkyl ester of lower alkanoic acid, carbamic acid tert-butyl ester, N-alkyl carbamic acid tert-butyl ester, —CH or a pharmaceutically acceptable salt thereof.