Patent ID: 6323343
Filing Date: 2001-11-27
Classification: C07D

Abstract:
A process for preparing a compound of formula (IV): ##STR5##wherein R.sup.1 is C.sub.1-4 alkyl, CH.sub.2 (C.sub.1-3 haloalkyl), benzyl, CH.sub.2 (C.sub.2-5 alkenyl) or CH.sub.2 (CH.sub.2-5 alkynyl), which comprises the steps:i. dehydrating a compound of formula (II): ##STR6##by reacting it with an acid chloride in the presence of an amine having a pKa in the range 3-11, at a temperatare in the range 0-110.degree. C., to give a compound of formula (III): ##STR7##and,ii. reducing a compound of formula (III) by catalytic hydrogenation.