Patent ID: 7776341
Filing Date: 2010-08-17
Classification: C07K,G01N

Abstract:
1. A peptide of a Mycobacteria tuberculosis (Mtb) protein selected from the group consisting of: (a) an isolated peptide that is a fragment of Mtb SodC protein (SEQ ID NO:2) encoded by Mtb gene Rv0432, which peptide is recognized by an antibody from a subject infected with Mtb, the sequence of which peptide is SEQ ID NO:52, SEQ ID NO:53, SEQ ID NO:54, SEQ ID NO:55, SEQ ID NO:56, SEQ ID NO:57, SEQ ID NO:58, SEQ ID NO:59, SEQ ID NO:60, SEQ ID NO:61, SEQ ID NO:62, SEQ ID NO:63, SEQ ID NO:64, SEQ ID NO:65, SEQ ID NO:66, SEQ ID NO:67, SEQ ID NO:68, SEQ ID NO:69, SEQ ID NO:70, SEQ ID NO:71, SEQ ID NO:72, SEQ ID NO:73, or SEQ ID NO:74; (b) an isolated peptide that is a fragment of Mtb BfrB protein (SEQ ID NO:3), which peptide is recognized by an antibody from a subject infected with Mtb, the sequence of which peptide is SEQ ID NO:75, SEQ ID NO:76, SEQ ID NO:77, SEQ ID NO:78, SEQ ID NO:79, SEQ ID NO:80, SEQ ID NO:81, SEQ ID NO:82, SEQ ID NO:83, SEQ ID NO:84, SEQ ID NO:85, SEQ ID NO:86, SEQ ID NO:87, SEQ ID NO:88, SEQ ID NO:89, SEQ ID NO:90, SEQ ID NO:91, or SEQ ID NO:92; and (c) an isolated peptide that is a fragment of Mtb TrxC protein (SEQ ID NO:4), which peptide is recognized by an antibody from a subject infected with Mtb, the sequence of which peptide is SEQ ID NO:93, SEQ ID NO:94, SEQ ID NO:95, SEQ ID NO:96, SEQ ID NO:97, SEQ ID NO:98, SEQ ID NO:99, SEQ ID NO:100, SEQ ID NO:101, SEQ ID NO:102, or SEQ ID NO:103.