Patent ID: 7348162
Filing Date: 2008-03-25
Classification: A01K,A61K,A61P,C07K,C12N

Abstract:
1. An isolated nucleic acid molecule comprising a nucleotide sequence: (a) as set forth in SEQ ID NO: 1; (b) of the DNA insert in ATCC Deposit No. PTA-1062; (c) encoding the polypeptide as set forth in SEQ ID NO: 2; or (d) that hybridizes to the complement of the nucleotide sequence of (c) at 65° C. in a hybridization and wash buffer comprising 0.015 M sodium chloride and 0.0015 M sodium citrate or at 42° C. in a hybridization and wash buffer comprising 0.015 M sodium chloride, 0.0015 M sodium citrate, and 50% formamide, and encoding a polypeptide that inhibits FGF-mediated growth in bone marrow stromal cells; or (e) that is complementary to the nucleotide sequence of any of (a)-(d).