Patent ID: 6042845
Filing Date: 2000-03-28
Classification: A61F,A61K,A61P,A61Q,Y10S

Abstract:
A method for the treatment of fungal diseases in nails, which comprises the topical administration to the affected nail, or to the affected nail and surrounding skin:(1) a compound represented by Formula (I): ##STR10## and (2) an effective amount of an antifungal drug is selected from the group consisting of itraconazole, pharmaceutically acceptable salts thereof and stereoisomers thereof, (1) being administered in an amount sufficient to enhance the permeation of said antifungal drug through nail tissue, and (1) and (2) being administered either prior to or concurrently with the topical administration to the nail of said antifungal drug and the composition is substantially free of urea.