Patent ID: 8048928
Filing Date: 2011-11-01
Classification: A61K,A61P

Abstract:
1. A method for treating hepatitis which comprises administering to a patient having hepatitis, as an active ingredient, an effective amount of a diarylsulfide or diarylether derivative having 2-amino-1,3-propanediol structure and represented by the following formula (I): wherein R 1 is a halogen atom, a trihalomethyl group, a hydroxyl group, a lower alkyl group having 1 to 7 carbon atoms, a phenyl group, an aralkyl group, a lower alkoxy group having 1 to 4 carbon atoms, a trifluoromethyloxy group, a phenoxy group, a cyclohexylmethyloxy group, a aralkyloxy group, a pyridylmethyloxy group, a cinnamyloxy group, a naphthylmethyloxy group, a phenoxymethyl group, a hydroxymethyl group, a hydroxyethyl group, a lower alkylthio group having 1 to 4 carbon atoms, a lower alkylsulfinyl group having 1 to 4 carbon atoms, a lower alkylsulfonyl group having 1 to 4 carbon atoms, a benzylthio group, an acetyl group, a nitro group, or a cyano group; R 2 is a hydrogen atom, a halogen atom, a trihalomethyl group, a lower alkoxy group having 1 to 4 carbon atoms, a lower alkyl group having 1 to 7 carbon atoms, a phenethyl group, or a benzyloxy group; R 3 is a hydrogen atom, a halogen atom, a trifluoromethyl group, a lower alkoxy group having 1 to 4 carbon atoms, a hydroxyl group, a benzyloxy group, a lower alkyl group having 1 to 7 carbon atoms, a phenyl group, a lower alkoxymethyl group having 1 to 4 carbon atoms, or a lower alkylthio group having 1 to 4 carbon atoms; X is O, S, SO or SO 2 ; and n is an integer of 1 to 4, or a pharmaceutically acceptable salt thereof.