Patent ID: 7413854
Filing Date: 2008-08-19
Classification: C07B,C07D,C07H,C12N,C12Q,C40B

Abstract:
1. A method for synthesizing a templated molecule, comprising the steps of: a) providing at least one template comprising of one or more codons, b) providing a first functional entity attached to a first zipping oligonucleotide capable of reversible interaction with a second zipping oligonucleotide, c) providing one or more building blocks, each building block comprising a further functional entity linked to an anti-codon by a linker, d) contacting the components provided in steps a), b) and c) with each other under conditions allowing for i) specific hybridization of building block anti-codon(s) to the codon(s) of the template(s) and ii) dimerization of two zipping oligonucleotides attached to different functional entities, e) allowing a further functional entity of the one or more building blocks provided in step c) to form a chemical connection to the first functional entity provided in step b), and f) obtaining a templated molecule attached to the template which directed the synthesis thereof.