Patent ID: 8823954
Filing Date: 2014-09-02
Classification: A61B,G01B,G01N

Abstract:
1. A method for noninvasive imaging of tissue, comprising the steps of: illuminating a location on a surface of the tissue using an incident beam of light characterized by a spatial coherence length L detecting light backscattered from the tissue, the backscattered light characterized by a scattering angle θ; obtaining spectra from the detected light, each of said spectra characterized by light intensity versus light wavelength λ for a given scattering angle θ at said coherence length L extracting information regarding both cellular architecture and nuclear morphology of cells in the tissue from the spectra, in accordance with different scattering models for different ranges of scattering angles; and constructing a three-dimensional (3D) image of both cellular architecture and nuclear morphology of the cells in the tissue.