Patent ID: 8232397
Filing Date: 2012-07-31
Classification: C07D

Abstract:
1. A process for the preparation of a compound of Formula (VII) according to the following reaction scheme: wherein: R is an alkyl or substituted alkyl; R R R R R M is selected from the group consisting of a metal cation having a charge of +1, and a metal cation group having a charge of +2; X is oxygen; and X the process comprising: (a) contacting a compound of Formula (I) with a dienophile in the presence of a solvent comprising water to form a compound of Formula (II); (b) contacting the compound of Formula (II) with an aprotic solvent and a catalyst that catalyzes hydrogen addition to form a compound of Formula (III); (c) contacting the compound of Formula (III) with R (d) contacting the compound of Formula (IV) with X (e) contacting the compound of Formula (V) with a hydrolysis agent to form the compound of Formula (VI); and (f) contacting the compound of Formula (VI) with MCO