Patent ID: 9212389
Filing Date: 2015-12-15
Classification: C12Q

Abstract:
1. A method of detecting an interaction between a first entity and a second entity, said method comprising: attaching at least segments, portions or fragments of said first entity to a surface of a thermal detector; preparing a sample to be analyzed, in which said second entity is suspected to be contained in the sample; applying said sample onto said surface of said thermal detector, thereby providing for said interaction; detecting an electric signal generated by a thermal sensor unit or an array of thermal sensor units of said thermal detector after applying said sample onto said surface of said thermal detector, said detecting said electrical signal consists of measuring the heat of reaction generated by a chemical or biological interaction upon binding, association or fusion of said first entity and said second entity; and comparing said electric signal to a predetermined value, the predetermined value including an electric signal generated by said thermal detector when said sample does not contain said second entity, thereby detecting the interaction between said first entity and said second entity.