Patent ID: 6169201
Filing Date: 2001-01-02
Classification: C07C

Abstract:
A process for the preparation of N-acylamino acids of the Formula I ##STR11## wherein R is hydrogen, a carboxyl group, a (C.sub.1 -C.sub.12)-alkyl group which may be saturated, which may be, straight chain, branched or cyclic, a (C.sub.2 -C.sub.12)-alkenyl group which may be mono- or polyunsaturated, straight chain, branched chain, or cyclic and a (C.sub.1 -C.sub.8)-acyloxy group, as well as a (C.sub.5 -C.sub.18)-aryl residue, R' is hydrogen, a saturated straight chain, branch chain or cyclic (C.sub.2 -C.sub.14)-alkenyl residue, a (C.sub.6 -C.sub.18)-alkyl-(C.sub.5 -C.sub.18)-aryl residue or a polyunsaturated (C.sub.2 -C.sub.10)-alkenyl-(C.sub.5 -C.sub.18) residue, which comprises reacting a compound of Formula II R'CN (II), R' has the value stated above with an aldehyde of general Formula III R--CHO (III), in which R has the meaning above in the presence of an acid, carbon monoxide and a metal catalyst.