Patent ID: 6221360
Filing Date: 2001-04-24
Classification: A61K,A61P,C07K,C12N

Abstract:
An infectious recombinant bovine herpesvirus comprising a foreign gene inserted into and inactivating a bovine herpesvirus gene in the virus genome,said foreign gene comprising a human cytomegalovirus immediate early promoter and a .beta.-galactosidase coding region, wherein said foreign gene is expressed at both early and late phases of infection as an authentic bovine herpesvirus gene,said .beta.-galactosidase coding region being derived from an organism different from humans and bovine herpesvirus,said human cytomegalovirus immediate early promoter being from a different organism than said bovine herpesvirus and said .beta.-galactosidase coding region,said recombinant bovine herpesvirus being capable of transfecting a host cell.