Patent ID: 7960398
Filing Date: 2011-06-14
Classification: A61K,C07C,C07D,C07F,C07K,G01N,Y02A

Abstract:
1. A method for inhibiting TNF-alpha activity or decreasing TNF-alpha activity in a subject suffering from restinosis, inflammatory disease of the central nervous system, aneurysmal aortic disease, traumatic joint injury, peridontal disease, macular degeneration, diabetic retinopathy, occular inflammation, keratoconus, Sjogren's syndrome, cachexia, anorexia, cerebral malaria, silicosis, asbestosis, pulmonary sarcoidosis, influenza, keloid formation, pyresis, chronic bronchitis, urticaria, allergic rhinitis, allergic conjunctivitis, eosiniophilic granuloma, or reperfusion injury of the myocardium and brain; said method comprising administering a compound according to FIG. 7 or a pharmaceutical composition comprising said compound to said subject.