Patent ID: 8168095
Filing Date: 2012-05-01
Classification: A61K,C09B,Y10T

Abstract:
1. A process for the preparation of amorphous particles comprising a homogeneous distribution of one or more dyes encapsulated by an amorphous, siliceous encapsulating agent, the process comprising: (a) providing a precursor of the encapsulating agent in liquid form; (b) providing the one or more dyes in liquid form; (c) mixing the liquid forms; (d) aerosolizing the mixture to form droplets comprising the one or more dyes and encapsulating agent; and (e) heating the droplets to form the particles comprising the one or more dyes encapsulated by the siliceous encapsulating agent; wherein at least one of the liquid forms provided is aqueous and the aqueous liquid form is acidic; wherein the dye is homogeneously dispersed throughout the amorpohous particles; and wherein dye leakage is less than 5% weight of the total amount of dye incorporated into the particle.