Patent ID: 8846867
Filing Date: 2014-09-30
Classification: A61K,A61P,C07K

Abstract:
1. An isolated anti-desmoglein 1 (Dsg1) antibody or fragment thereof comprising a heavy chain (V H ) encoded by the gene selected from the group consisting of VH1-18, VH1-08, VH3-09, VH3-07, VH3-30, VH4-b, VH3-53, VH3-66, and any combination thereof; and a light chain (V L ) encoded by the gene selected from the group consisting of A30, B3, L1, L2, L8, L11, L12, LFVK431, O12O2, O18O8, 1c, 1e, 1g, 6a, 3h, and any combination thereof.