Patent ID: 6858610
Filing Date: 2005-02-22
Classification: A61P,C07D

Abstract:
1. A compound having potassium channel inhibitory activity of formula (I), or a pharmaceutically acceptable salt thereof: wherein, A, B, and D are selected from a substituted carbon atom, a nitrogen atom or N→O, wherein at least one of A, B, and D is a substituted carbon atom, wherein at least one of A, B and D is a nitrogen atom or N→O and at most only one of A, B and D is N→O; E and G are each hydrogen, or E and G taken together form a bond; R Y is selected from a bond, alkyl, carbocycloalkyl, alkenyl, alkynyl, aryl, heteroaryl, and heterocyclo; X is one of C═O, C═S or SO R R R R Z is selected from hydrogen, alkyl, hydroxy, SH, alkoxy, aryloxy, alkylthio, amino, substituted amino, alkoxycarbonyl, alkanoylamido, aroylamido, heterocyclocarbonylamido, heteroaroylamido, alkanoyl(alkylsubstituted)amido, aroyl(alkylsubstituted)amido, heteroaroyl(alkylsubstituted)amido, and heterocyclocarbonyl(alkyl substituted)amido; with the provisos that i) when R