Patent ID: 6927228
Filing Date: 2005-08-09
Classification: A61K,A61P,A61Q,C07C,C07D

Abstract:
1. A compound having the following structural formula (I): in which R 1 is a radical of formula (a) below: wherein Y is as defined below; R 2 and R 3 , which may be identical or different, are each a hydrogen atom, an alkyl radical having from 1 to 12 carbon atoms, an aryl radical, a halogen atom, a radical —OR 7 , a polyether radical, a nitro group or an amino group which may optionally be substituted with one or more alkyl radicals having from 1 to 12 carbon atoms, wherein R 7 is as defined below; X is the structural linkage below: wherein said structural linkage can be read from left to right or vice versa, and Z, W, m, n, p and q are as defined below; R 4 is an alkyl radical having from 1 to 12 carbon atoms, an aryl radical, an aralkyl radical, or a 9-fluorenylmethyl radical; Y is a sulfur atom ; R 7 is a hydrogen atom, an alkyl radical having from 1 to 12 carbon atoms or an aralkyl radical; Z is an oxygen or sulfur atom or a radical —N—R 12 , wherein R 12 is as defined below; W is an oxygen or sulfur atom, a radical —NR 13 or a ═CH 2 radical, wherein R 13 is as defined below; m, n, p and q, which may be identical or different, are each 0 or 1, with the proviso that the sum m+n+p+q is greater than or equal to 2 and that when p is 0 then n or q is equal to 0; R 12 is a hydrogen atom or an alkyl radical having from 1 to 12 carbon atoms; R 13 is a hydrogen atom or an alkyl radical having from 1 to 12 carbon atoms; or an optical or geometrical isomer or salt thereof.