Patent ID: 6835736
Filing Date: 2004-12-28
Classification: A61K,C07D

Abstract:
A method for inhibiting the growth of cancer cells, said method comprising administering to said cells an effective amount of a compound, or a salt thereof, wherein said compound has the following structure: wherein R1 is selected from the group consisting of hydrogen, C1-C5 alkyl, and COR5; wherein R5 is selected from the group consisting of C1-C5 alkyl and phenyl; R2 is selected from the group consisting of SR6, SCOR7, and OR8; wherein R6 is selected from the group consisting of C1-C5 alkyl and phenyl; R7 is selected from the group consisting of C1-C5 alkyl and phenyl; and R8 is selected from the group consisting of hydrogen, C1-C5 alkyl, COR5 and phenyl; R3 is selected from the group consisting of hydrogen, OR9, and OCOR10; wherein R9 is selected from the group consisting of hydrogen and C1-C5 alkyl; and R10 is selected from the group consisting of C1-C5 alkyl and phenyl; or R3 is connected to C3 with a double bond in which case R3 is oxygen; R4 is selected from the group consisting of hydrogen and halides; and wherein each of the bonds between C1-C2, C4-C5, C7-C8, and C16-C17 may, independently, be either single or double bonds.