Patent ID: 9163085
Filing Date: 2015-10-20
Classification: A61K,A61P,C07K

Abstract:
1. An isolated antibody or an antigen-binding portion thereof which binds to and agonizes OX40 comprising: (a) a heavy chain variable region CDR1 comprising the amino acid sequence of SEQ ID NO: 25; (b) a heavy chain variable region CDR2 comprising the amino acid sequence of SEQ ID NO: 26; (c) a heavy chain variable region CDR3 comprising the amino acid sequence of SEQ ID NO. 27; (d) a light chain variable region CDR1 comprising the amino acid sequence of SEQ ID NO. 32; (e) a light chain variable region CDR2 comprising the amino acid sequence of SEQ ID NO. 33; and (f) a light chain variable region CDR3 comprising the amino acid sequence of SEQ ID NO. 34.