Patent ID: 8992916
Filing Date: 2015-03-31
Classification: A61K,A61P,C07K,C12N,C12P,Y10S

Abstract:
1. A method for treating atopic dermatitis, comprising administering to a subject in need thereof an effective amount of a composition comprising an antibody, or functional fragment thereof, that binds human interleukin-13, wherein said antibody or a functional fragment thereof comprises H-CDR1, H-CDR2 and H-CDR3 selected from (i)-(ii): (i) SEQ ID NO: 6, SEQ ID NO: 8 and SEQ ID NO: 9, respectively; and (ii) SEQ ID NO: 7, SEQ ID NO: 8, and SEQ ID NO: 10, respectively; and comprises L-CDR1, L-CDR2 and L-CDR3 selected from (iii)-(v): (iii) SEQ ID NO: 16, SEQ ID NO: 19, and SEQ ID NO: 20, respectively; (iv) SEQ ID NO: 17, SEQ ID NO: 19, and SEQ ID NO: 21, respectively; and (v) SEQ ID NO: 16, SEQ ID NO: 19, and SEQ ID NO: 22, respectively; and comprising a pharmaceutically acceptable carrier or excipient therefore.