Patent ID: 6593365
Filing Date: 2003-07-15
Classification: C07C

Abstract:
A method for treating and/or controlling thrombosis in a mammal, comprising administering to a mammal in need thereof an effective dosage of a compound having the formula: whereinn is3 to 13 X is each independently a halogen, X being on one or more of the phenyl carbon atoms; R is selected from the group consisting of hydrogen, halogen, lower alkyl, and lower alkoxy; R1 is selected from the group consisting of hydroxy, amino, lower alkoxy, lower alkylamino, di(lower alkyl) amino, diloweralkylaminoloweralkylamino, diloweralkylaminoloweralkoxy, hydroxyloweralkoxy, polyhydroxyloweralkoxy, loweralkoxyloweralkoxy, phenyl-loweralkoxy, phenoxy, substituted phenoxy, carboxy, carbloweralkoxy, loweralkanoylamino-loweralkoxy, hydrazino, hydroxylamino, N-morpholino, N-(4-loweralkylpiperidino), N-[4-(hydroxyloweralkyl)-piperidino], (hydroxyloweralkyl) amino, and a naturally occurring amino acid radical with attachment at the a-amino nitrogen; R2 is each independently hydrogen or a halogen; and R3 is selected from the group consisting of hydrogen, 3- and 4-lower alkyl, lower alkoxy, benzyl and halo; or a pharmaceutically acceptable salt thereof.