Patent ID: 6468963
Filing Date: 2002-10-22
Classification: A61K

Abstract:
A pharamaceutical formulation adapted for administration to human patients, said pharmaceutical formulation comprising (a) an effective amount of an anti-diabetic agent; (b) an toxicity reducing amount of a agent of the formula:R1â€”Sâ€”R2;â€ƒâ€ƒ(I) wherein:R1 is hydrogen, X-lower alkyl, or X-lower alkylene-R3; R2 is -lower alkylene-R4; R3 and R4 are each individually SO3M or PO3M2; X is absent or X is sulfur; and M is hydrogen or an alkali metal; or a pharmaceutically acceptable salt thereof; and (c) one or more pharmaceutically acceptable solvents, excipients, diluents or preservatives.