Patent ID: 8445009
Filing Date: 2013-05-21
Classification: A61F,A61K,A61L,A61P,C12Y

Abstract:
1. A process for producing a solid dressing for treating wounded tissue in a mammal comprising: (a) forming a liquid aqueous mixture of a fibrinogen component selected from the group consisting of human fibrinogen and bovine fibrinogen, and a fibrinogen activator selected from the group consisting of human thrombin, bovine thrombin and recombinant human thrombin, at a temperature of 2° C. to 8° C., where said liquid aqueous mixture contains up to 9% γ-γ dimers; (b) reducing the temperature of said aqueous mixture to form a frozen aqueous mixture, wherein said frozen aqueous mixture contains up to 9% γ-γ dimers; and (c) reducing the moisture content of said frozen aqueous mixture to produce a solid dressing having a haemostatic layer consisting essentially of said fibrinogen component and said fibrinogen activator, wherein said haemostatic layer contains up to 9% γ-γ dimers.