Patent ID: 7125546
Filing Date: 2006-10-24
Classification: A61K,A61P,C08G

Abstract:
1. A complex which comprises a block copolymer represented by Formula I or II: wherein in Formula I and II, R 1 represents independently a hydrogen atom, a C 1-20 alkyl group or a C 1-20 alkyl group substituted with one or two substituents selected from the group consisting of acetal, hydroxyl, aldehyde, amino and mercapto; A represents independently NH, CO or R 5 (CH 2 ) p R 6 , in which R 5 is O, OCO, OCONH, NHCO, NHCOO, NHCONH, CONH or COO; R 6 is NH or CO; and p is an integer of 1 to 6; R 2 represents independently a hydrogen atom or an alkyl group or an aralkyl group, provided that a hydrogen atom accounts for 95% or more of all R 2 ; R 3 represents independently a hydrogen atom or in the case of Formula I, R 3 is C 8-16 alkylcarbonyl, phenylacetyl, diphenylacetyl or pyrenesulfonyl, and in the case of Formula II, R 3 is C 8-16 alkyl, benzyl, benzhydryl, adamantyl or cholesteryl; m is independently an integer of 50 to 5000; and n is independently an integer of 5 to 500; and cisplatin, wherein one or two chlorine ions in the cisplatin are replaced with the carboxyl anion of the block copolymer.