Patent ID: 8003664
Filing Date: 2011-08-23
Classification: A61P,C07D

Abstract:
1. A method of treating a disorder of reduced motility of the gastrointestinal tract in a mammal, the method comprising administering to the mammal a therapeutically effective amount of a pharmaceutical composition comprising a pharmaceutically-acceptable carrier and a compound of formula (I-a): wherein: R R R W is selected from (a) Y, wherein Y is selected from —N(R (b) a moiety of formula (b): wherein X is selected from —N(R R R R or R or R R R R or R R R R R R a is 0 or 1; and n is an integer of 1, 2, or 3; provided that when n is 1, X is —SR or a pharmaceutically-acceptable salt or stereoisomer thereof.