Patent ID: 6916824
Filing Date: 2005-07-12
Classification: A61K,Y10S

Abstract:
1. A method of treating cataracts, retinopathy, lens cell damage and retinal cell damage caused by diabetes comprising administering to a patient an effective amount of one or more compounds of the formula: wherein: T is independently CR, NR, NR, S or O; X is independently O, NR, N or S; Y is independently O, NR, N or S; Z is independently C, N, S or O; R wherein R is independently H, OH, alkyl, alkenyl, alkynyl, an aromatic ring system, amino, sulfhydryl, or sulfonyl, M is a divalent alkyl, alkenyl or alkynyl, aromatic ring system, or sulfonyl, W is Cl, F, Br or OCl, and A is an aromatic ring system; R R R R and pharmaceutically acceptable salts or esters of the foregoing, as well as optical isomers thereof.