Patent ID: 8329673
Filing Date: 2012-12-11
Classification: A61K,A61P,C08B,C08L,Y02A

Abstract:
1. A method of treating an ocular or ophthalmic condition selected from the group consisting of ocular rosacea, ocular inflammatory disease, blepharitis, conjunctivitis or allergic conjunctivitis, corneal inflammation, corneal scarring, corneal ulceration, corneal damage or trauma, conjunctiva damage or trauma, diabetic retinopathy, dry eye or dry eye syndrome, iritis, keratitis, uveitis, and age-related macular degeneration in a subject, said method comprising administering an effective amount of a compound which is a modified hyaluronan or a pharmaceutically acceptable salt or ester thereof comprising at least one sulfate group and the primary C-6 hydroxyl proton of at least one N-acetyl-glucosamine residue substituted with an unsubstituted C 1 -C 10 alkyl group to a subject symptomatic of or predisposed to at least one of said ocular or ophthalmic conditions.