Patent ID: 7851466
Filing Date: 2010-12-14
Classification: A61K,A61P

Abstract:
1. A method of inhibiting IL-23 in vitro comprising administering to a cell a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein aryl, or heteroaryl; each of R R R n is 0, 1, 2, 3, 4, 5, or 6; X is O, S, S(O), S(O Y is a covalent bond, CH Z is N or CH; one of U and V is N, and the other is CR W is O, S, S(O), S(O in which each of R a and R b , independently, is H, alkyl, aryl, heteroaryl; and each of R c and R d , independently, is H, alkyl, aryl, heteroaryl, cyclyl, heterocyclyl, or alkylcarbonyl.