Patent ID: 6638924
Filing Date: 2003-10-28
Classification: A61K,C07D

Abstract:
A compound of the Formula: wherein: M is a monovalent, divalent, trivalent, or tetravalent metal cation; AL is an apical ligand; with the proviso that AL is not derived from acetic acid, nitric acid, or hydrochloric acid; n is 1 when M is a divalent cation, or n is 2 when M is a trivalent cation; R1, R2, R3, R4, R5, R6, R7, R8, and R9, are independently chosen from the group consisting of hydrogen, halogen, hydroxyl, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted haloalkyl; alkylalkoxy, nitro, acyl, optionally substituted alkoxy, saccharide, optionally substituted amino, carboxyl, optionally substituted carboxyalkyl, optionally substituted carboxyamide, optionally substituted carboxyamidealkyl, optionally substituted heterocycle, optionally substituted cycloalkyl, optionally substituted arylalkyl, optionally substituted heteroarylalkyl, optionally substituted heterocycloalkylalkyl; and a group â€”Xâ€”Y, in which X is a covalent bond or a linker and Y is a catalytic group, a chemotherapeutic agent, or a site-directing molecule, and; R5, R10, R11, and R12 are independently hydrogen, optionally substituted alkyl, optionally substituted aryl, optionally substituted alkoxy, optionally substituted carboxyalkyl, or optionally substituted carboxyamidealkyl; with the proviso that the halogen is other than iodide and the haloalkyl is other than iodoalkyl.