Patent ID: 6080859
Filing Date: 2000-06-27
Classification: C07D

Abstract:
A pyrroloindole derivative having a carbamoyloxy group represented by the following general formula (1) below, an optically active isomer thereof, and a pharmacologically acceptable salt thereof: ##STR36## where R.sup.1 is OH, or a pyrrolidinyl group; n is 1 or 2; R.sup.2 is a lower alkyl group of C.sub.1 -C.sub.4 ; X--Y or Y--X is CH.sub.2, CHOH, CH.sub.2 -CH.sub.2, O--CH.sub.2, or NMe--CH.sub.2 ; Z.sup.1 is Cl or Br; and Ar.sup.1 is ##STR37## wherein Z.sup.2 is O or NH, m is 0 or an integer of 1 to 4, ##STR38## wherein m is 0 or an integer of 1 to 4, ##STR39## wherein m is 0 or an integer of 1 to 4, ##STR40## wherein Z.sup.3 is O or NH; Ar.sup.2 is any of the above groups a, b, c, and d.