Patent ID: 6056859
Filing Date: 2000-05-02
Classification: B01L,C12Q,G01N

Abstract:
A method for staining immobilized nucleic acids, comprising the steps of:providing a microchip structure including a solid substrate having at least one channel disposed thereon;affixing at least one DNA probe to said solid substrate;causing target DNA material to move through said at least one channel into proximity with said at least one DNA probe, whereby the target DNA can hybridize with said at least one DNA probe; andcausing a fluorescent dye to move through said at least one channel into proximity with hybridized target DNA, whereby the fluorescent dye binds to the hybridized DNA to enable subsequent detection of fluorescence, at least one of said target DNA material and said fluorescent dye being caused to move through said at least one channel under the influence of an externally applied electric potential.