Patent ID: 7629126
Filing Date: 2009-12-08
Classification: C12N,C12Q

Abstract:
1. A method of identifying anti-type 2 diabetes mellitus drugs, the method comprising: a) determining expression level of a PIM-3 nucleic acid molecule in a first adipocyte in the presence of a candidate compound wherein the PIM-3 nucleic acid molecule is selected from the group consisting of SEQ ID NO. 1, SEQ ID NO. 3, SEQ ID NO. 5 and SEQ ID NO. 7; b) determining expression level of the PIM-3 nucleic acid molecule in a second adipocyte in the absence of the candidate compound, and c) identifying an anti-type 2 diabetes mellitus drug by determining whether there is a difference in PIM-3 expression in the first adipocyte in the presence of the candidate compound compared to PIM-3 expression in the second adinocyte in the absence of candidate compound.