Patent ID: 7749486
Filing Date: 2010-07-06
Classification: A01K,C12N,G01N

Abstract:
1. A method for evaluating a candidate drug or protocol for the treatment of a tumor comprising (a) injecting an athymic mouse intraperitoneally with GFP-expressing tumor cells selected from the group consisting of melanoma, breast, prostate, lung, pancreatic, and colorectal cells; (b) administering a candidate drug or protocol to said mouse; (c) removing ascites for evaluation; (f) quantifying the level of GFP in a sample of the ascites using laser-scanning fluoroscopy; and (g) comparing the level of GFP in the ascites to that from a control animal which has not been treated with said candidate drug or protocol; wherein a decreased level of GFP in the treated sample denotes that the candidate drug or protocol is useful in the treatment of said tumor.