Patent ID: 6133460
Filing Date: 2000-10-17
Classification: A61L,A61M,A61P,C07D,C12N

Abstract:
A psoralen compound of the formula selected from the group consisting of ##STR15## a) a substituent A on the pyrone ring, selected from the group consisting of:--(CH.sub.2).sub.u --NH.sub.2,--(CH.sub.2).sub.w --J--(CH.sub.2).sub.z --NH.sub.2,--(CH.sub.2).sub.w --J--(CH.sub.2).sub.x --K'(CH.sub.2).sub.z --NH.sub.2, and--(CH.sub.2).sub.w --J--(CH.sub.2).sub.x --K--(CH.sub.2).sub.y --L--(CH.sub.2).sub.z --NH.sub.2 ;wherein J, K, and L are independently selected from the group consisting of O and NH, in which u is a whole number from 1 to 10, w is a whole number from 1 to 5, x is a whole number from 2 to 5, y is a whole number from 2 to 5, and z is a whole number from 2 to 6; andb) substituents B, R.sub.3, R.sub.4, R.sub.5, and R.sub.6 on the pyrone ring, 5-, 4'-, 5'- and 8-carbon atoms respectively, independently selected from the group consisting of --H and --(CH.sub.2).sub.v CH.sub.3, where v is a whole number from 0 to 5; or a salt thereof.