Patent ID: 6277259
Filing Date: 2001-08-21
Classification: G01N

Abstract:
An automated and integrated proteome analyzer comprising:a separation cassette for providing multi-dimensional separation of a proteinaceous sample, wherein the cassette includesa first dimension separation compartment housing a material having capillary channels, the proteinaceous sample being disposed in the capillary channels for first dimension separation;a second dimension separation compartment housing a separation medium, the separation medium receiving the proteinaceous sample for second dimension separation; anda power supply configured to apply an electric field across either the first dimension compartment or the second dimension compartment;an illumination and detection system positioned adjacent the second dimension separation compartment for illuminating and detecting the separated proteinaceous sample during second dimension separation; andan analysis system for processing data received from the illumination and detection system and formatting the data into a two-dimensional map representing the separated proteinaceous sample.