Patent ID: 9034323
Filing Date: 2015-05-19
Classification: A61K,A61P

Abstract:
1. A method for controlling post-prandial glucose levels in a subject, comprising administering to the subject a regular insulin and a hyaluronan-degrading enzyme between 5 and 15 minutes before a meal, whereby the action of the regular insulin has an onset and a duration of action of a fast-acting insulin analog, wherein: the amount of hyaluronan degrading enzyme administered is sufficient so that the regular insulin can be administered between 5 and 15 minutes before a meal; the sufficient amount of a hyaluronan degrading enzyme is 1 Unit or more hyaluronidase activity/mL; and administration of the regular insulin and the hyaluronan degrading enzyme is effected via subcutaneous, intradermal, intramuscular or intraperitoneal administration.