Patent ID: 7666639
Filing Date: 2010-02-23
Classification: A61K,A61P,C12N,C12Y,Y02A

Abstract:
1. An isolated deoxyribonucleoside kinase enzyme comprising a contiguous amino acid sequence which, when aligned with SEQ ID NO:6 according to the BLASTP algorithm using the scoring matrix BLOSUM62, open gap penalty 11, extension gap penalty 1, the highest scoring alignment yields a percentage identity in the range of overlap which, as calculated by the NCBI implementation of BLASTP, is at least 80%, and such range of overlap is at least 50 amino acids, and which enzyme has dCK/dGK-like deoxyribonucleoside kinase activity wherein the percentage identity, determined over the entire length of SEQ ID NO:6, is at least 80%.