Patent ID: 8105770
Filing Date: 2012-01-31
Classification: C12Q,Y10T

Abstract:
1. A method for detecting amplification or deletion in a test genomic DNA fragment, which comprises: (a) labeling a test genomic DNA fragment which is a genomic DNA fragment derived from the objective cell to be inspected with either one of a labeling substance of formula (1) or a labeling substance of formula (2), and labeling a control genomic DNA fragment which is used as a standard for detecting difference from said test genomic DNA fragment with the other labeling substance, wherein R R R R wherein R R R R (b) competitively hybridizing the labeled test genomic DNA fragment and the labeled control genomic DNA fragment with a sample nucleic acid comprising a nucleotide sequence for detecting difference between the test genomic DNA fragment and the control genomic DNA fragment; and (c) detecting amplification or deletion in the test genomic DNA fragment by using the obtained fluorescence intensity as an indicator.