Patent ID: 6352630
Filing Date: 2002-03-05
Classification: C12Q,G01N

Abstract:
An electrochemical system for measuring a value representing the coagulation time of a drop of whole blood wherein said system includes:an electrochemical sensor in the shape of a strip bearing at least a reference electrode and a working electrode on which a specific reagent is immobilised on a measuring zone, the composition of said reagent incorporating at least a thromboplastin having a quantity of negative phospholipids greater than that of positive phospholipids, a buffer medium and an oligopeptidic substrate, one terminal link of which can be cut off by the thrombin enzyme to give charged groups (LG), and a portable measuring apparatus dimensionally configured to receive the sensor and having an electronic circuit, which is supplied with power by a power source, allowing a variable or non variable electric current or a variable or non variable potential difference to be imposed across the electrodes of the sensor, said measuring apparatus having means for processing the electric signal resulting from the migration of the charged groups (LG), means for correlating said signal with a value representative of the coagulation time, and means for displaying said value on a display device of said measuring apparatus.