Patent ID: 6809096
Filing Date: 2004-10-26
Classification: A61P,C07D

Abstract:
Compounds of formulae: in which:R1, R2, R3, R4 and R5 are selected from hydrogen, halogens, C1-C6 alkyl groups, hydroxyl, â€”CHO, â€”OR8, â€”COOH, â€”CN, â€”CO2R8, â€”CONHR8, â€”CONR8R9, â€”NH2, â€”NHR8, â€”N(R8)2, â€”NHâ€”CH2â€”CH2â€”N(CH3)2, â€”NHâ€”CH2â€”CH2â€”Cl, â€”NHCOR8, morpholino, nitro, SO3H, R8 and R9 being selected from C1-C6 alkyl groups and phenyl(C1-C4)alkyl groups and Ar being a C6-C14 aryl group, R6 is selected from hydrogen, halogens, C1-C6 alkyl or â€”(CH2)nR10 groups with R10 being selected from halogens or â€”OH, (C1-C6)alkoxy or â€”Oâ€”COâ€”(C1-C6)alkyl groups and n between 1 and 6, â€”CN, â€”CO2Et or â€”COR11 groups with R11 being selected from C1-C6 and phenyl(C1-C4)alkyl groups, and â€”NR12R13 groups with R12 and R13 selected, independently of one another, from hydrogen or C1-C6 alkyl, phenyl(C1-C4)alkyl or â€”(CH2)nR14 groups with R14 being selected from halogens or (C1-C6)alkoxy and â€”N(CH3)2 groups and n between 1 and 6, R7 is selected from hydrogen, (C1-C6)alkyl, phenyl (C1-C4)alkyl, â€”NR15R16 with R15 and R16 selected, independently of one another, from hydrogen, C1-C6 alkyl and phenyl(C1-C4)alkyl and â€”(CH2)nR17, with R17 selected from hydrogen, halogens or â€”OH or (C1-C6)alkoxy groups and n between 1 and 6, and the addition salts of these compounds with pharmaceutically acceptable acids.