Patent ID: 6579900
Filing Date: 2003-06-17
Classification: A61K,A61P,C07D

Abstract:
A method for inducing analgesia in an individual or animal comprising administering to the individual or animal a therapeutically effective amount of a compound represented by the following structural formula:Râ€”Xâ€”Y and physiologically acceptable salts thereof, wherein:R is selected from the group consisting of a methyl group, an aryl group, a substituted aryl group, a heteroaryl group, a substituted heteroaryl group, a heterocyclic group and a substituted heterocyclic group; X is a straight chain hydrocarbyl group or a substituted straight chain hydrocarbyl group containing from about 4 to about 18 carbon atoms if R is an aryl group, a substituted aryl group, a heteroaryl group, a substituted heteroaryl group, a heterocyclic group or a substituted heterocyclic group; X is a straight chain hydrocarbyl group or a substituted straight chain hydrocarbyl group containing from about 10 to about 24 carbon atoms if R is a methyl group; and Y is a moiety capable of irreversibly binding to a nucleophilic group at the active site of an amidase enzyme.