Patent ID: 8663147
Filing Date: 2014-03-04
Classification: A61K,A61P,C07K,Y10T

Abstract:
1. A method for treating a patient suffering from Thromboangiitis obliterans comprising: (a) providing a column having coupled thereto a specific ligand for human immunoglobulin, (b) passing plasma taken from a patient suffering from Thromboangiitis obliterans over the column under conditions which effect the binding of said specific ligand to immunoglobulin in the plasma of the patient, (c) removing a significant portion of immunoglobulin from the plasma, and (d) reinfusing the patient's plasma into the patient and thereby treating the patient, wherein said specific ligand is selected from the group consisting of polyclonal anti-human immunoglobulin antibodies, monoclonal anti-human immunoglobulin antibodies, a fragment of such antibodies, recombinant molecules of the antibody idiotype, synthesized peptides, Protein A and Protein G; and wherein said method: