Patent ID: 8871738
Filing Date: 2014-10-28
Classification: A61K,A61P,C07D

Abstract:
1. A compound of Formula I, or a pharmaceutically acceptable salt thereof, wherein R R R HET(3) is a 3-6 membered heterocyclic ring having 1-3 heteroatom groups which are each independently N, NH, O, S, S(O), or S(O) x is 0 or 1; The dashed lines in Formula I represent one optional double bond between 2 adjacent carbon atoms; D D D R Each R A Each HET(1) is a 5- or 6-membered heterocyclic ring having 1-4 heteroatom groups which are each independently —N—, —NH—, —S—, —O—, —S(O)—,or —S(O) Z is A A HET(2) is a 5-6 membered heterocyclic ring having 1-3 heteroatom groups which are each independently N, NH, O, or S, optionally having one group —C(═O)—, and optionally having 1-3 double bonds; A a is 0 or an integer from 1-3.