Patent ID: 8367829
Filing Date: 2013-02-05
Classification: A61P,C07D

Abstract:
1. A compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein: X is selected from: wherein R or X is a bicyclic, fused heterocyclic ring selected from the group of: wherein said bicyclic fused heterocyclic ring is optionally substituted with one, two, or three additional substituents independently selected from alkyl, oxo, and OH; R wherein said alkylene, alkenylene, alkynylene, cycloalkylene, or arylene is optionally substituted with 1, 2, or 3 substituents selected from halo, oxo, and OR Het is 5-membered or 6-membered saturated or unsaturated heterocyclene selected from the group of: and wherein said 5-membered or 6-membered saturated or unsaturated heterocyclene is optionally substituted with 1, 2, or 3 substituents selected from halo, alkyl, alkoxy, oxo, and OH; R Y is C(O), C(O)N(R R R R wherein Z is O, S, S(O) R