Patent ID: 6489337
Filing Date: 2002-12-03
Classification: A61K,A61P,C07D

Abstract:
A method for treating disorders mediated by the histamine H3 receptor in a patient, said method comprising administering to the patient a pharmaceutically effective amount of compound of formula (I): whereinX is H or one or more of halogen, hydroxy, C1-3 alkoxy, benzyloxy, or C1-6 alkyl; R is H or Ar; R1 is H, methyl, or Ar; Ar is â€”(C&boxH;O)nâ€”Phâ€”Oâ€”(CH2)mâ€”N(R2)2; R2is C1-6 alkyl; n is 0 or 1 when R is Ar or 1 when R1 is Ar; m is2-6; at least one of R and R1 is Ar; and both of R and R1 are not Ar; or a pharmaceutically acceptable salt, ester, or amide thereof.