Patent ID: 8574420
Filing Date: 2013-11-05
Classification: A61K,C08L

Abstract:
1. A method for controlling the release of one or more anions (as a function of time) from a film which comprises the steps of: (i) forming a polyelectrolyte assembly wherein the polyelectrolyte assembly comprises at least two anion/cationic polymer bilayers comprising one or more different anion/cationic polymer bilayers where at least a first bilayer is formed from a first cationic polymer and at least a second bilayer is formed from a second cationic polymer wherein the cationic polymers are selected from where: n+m+l+k+i=N, the total number of repeat units in the polymer; n, m, l, k and i are all integers; or m and l are integers, n is zero or an integer and i and k are zero; or m and l are integers, and n, i or k is zero or an integer; A Z R R or where n+m=N is the number of repeating units in the polymer; each y, independently, is 1, 2 or 3; each x, independently, is an integer ranging from 1-10; each R wherein the first cationic polymer is selected from cationic polymers of formula I and the second cationic polymer is selected from cationic polymers of formula II, or wherein the first and second polymers are selected from cationic polymers of formula II and differ from each other in the value of (n)/N; and (ii) subjecting the polyelectrolyte assembly formed to conditions in which ester functions in the polymer of formula I or in the polymer of formula II are hydrolyzed to release the one or more anions.