Patent ID: 6303603
Filing Date: 2001-10-16
Classification: A61P,C07D

Abstract:
A 3-oxo-(2H)-1,2,4-triazine derivative selected from those of formula I ##STR49##in whichr.sub.1 represents:a linear or branched C.sub.1 -C.sub.4 alkyl group ora phenyalkyl group, the phenyl nucleus optionally being substituted by one or more C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.3, alkoxy, halogen, and trifluoromethyl,R.sub.2 represents;hydrogen ora linear or branched C.sub.1 -C.sub.4 alkyl radical ora phenyl or phenyalkyl group, the phenyl nucleus optionally being substitued by one or more C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.3 alkoxy, halogen, and trifluoromethyl,A represents oxygen,R.sub.3 represents hydrogen or methyl,B represents a group ##STR50##in which Ar represents phenyl, pyridyl, or pyrimidyl, optionally substituted by one or more C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 alkoxy, hydroxyl, trifluoromethyl, and halogen, and n is 3 to5,in the form of a racemic mixture or an enantiomer or diastereoisomer thereof and pharmaceutically-acceptable inorganic or organic salts thereof.