Patent ID: 9012135
Filing Date: 2015-04-21
Classification: A01N,A61K,C07H,C09K,C12N,C12Q,G01N

Abstract:
1. A composition for preserving nucleic acids comprising: a reducing agent, glutathione, wherein the glutathione is present in an amount from about 10 mM to about 200 mM; a first chaotropic substance, LiCI, wherein the LiCI is present in an amount of from about 1 M to about 4 M; a second chaotropic substance, guanidine hydrochloride, wherein the guanidine hydrochloride is present in an amount from about 0.1 M to about 0.9 M; a third chaotropic substance, urea, wherein the urea is present in an amount from about 2 M to about 12 M; a first polyamine substance, spermidine, wherein the spermidine is present in an amount from about 10 μM to about 300 μM; a second polyamine substance, biuret, wherein the biuret is present in an amount of from about 10 mM to about 100 mM; and a chelating agent, EDTA, wherein the EDTA is present in an amount of from about 1 mM to about 200 mM.