Patent ID: 6221879
Filing Date: 2001-04-24
Classification: A61K,A61P,C07D

Abstract:
A compound in the form of a pure geometrical isomer or a mixture of such isomers, corresponding to the general formula (I) ##STR17##in whichU representsA) either a 2,3-dihydro-1H-inden-2-yl group of general formula (A) ##STR18##B) or a heterocyclic group of general formula (B) ##STR19##in whichV represents a hydrogen or halogen atom, a (C.sub.1 -C.sub.3) alkyl group or one or two (C.sub.1 -C.sub.3) alkoxy groups,W and X each represent, respectively, either two oxygen atoms, or an oxygen atom and a CH.sub.2 group, or a CH.sub.2 group and an oxygen atom, or an oxygen atom and a CO group, n represents the number 0 or 1,R represents either a propyl group when U represents a 2,3-dihydro-1H-inden-2-yl group of general formula (A), or a hydrogen atom or a (C.sub.1 -C.sub.3) alkyl group when U represents a heterocyclic group of general formula (B),Y represents one or more atoms or groups chosen from the following: hydrogen, halogen, (C.sub.1 -C.sub.3) alkyl and (C.sub.1 -C.sub.3) alkoxy, andZ represents two hydrogen atoms or an oxygen atom;or a pharmaceutically acceptable acid-addition salt thereof.