Patent ID: 6017915
Filing Date: 2000-01-25
Classification: A61P,C07D

Abstract:
A compound of formula I ##STR14## wherein R.sup.1 and R.sup.2 independently are hydrogen, halogen, trifluoromethyl, hydroxy, C.sub.1-6 -alkyl or C.sub.1-6 -alkoxy; andR.sup.3 is hydrogen or C.sub.1-3 -alkyl; andA is C.sub.1-3 -alkylene; andY is CH--CH2--, C.dbd.CH--, CH--O-- or C.dbd.N--, CH--CH.sub.2 --, C.dbd.CH--, CH--O-- or C.dbd.N--, wherein only the underscored atom participates in the ring system; andZ is ##STR15## wherein n is 1 or 2; R.sup.11 is hydrogen or C.sub.1-6 -alkyl; R.sup.14 is --(CH.sub.2).sub.m OH or --(CH.sub.2).sub.t COR.sup.15wherein m is 0, 1, 2, 3, 4, 5 or 6, t is 0 or 1, and R.sup.15 is --OH, NH.sub.2, --NHOH or C.sub.1-6 -alkoxy; or a pharmaceutically acceptable salt thereof.