Patent ID: 7645592
Filing Date: 2010-01-12
Classification: A61K,A61P,C07K,G01N

Abstract:
1. A method for detecting a soluble glycoprotein VI (GPVI) polypeptide or peptide in a sample, comprising the steps of: a. contacting the sample with a first monoclonal antibody specific for the GPVI polypeptide or peptide, b. capturing the GPVI polypeptide or peptide in the sample with the first monoclonal antibody, c. contacting the sample with a second monoclonal antibody specific for the GPVI polypeptide or peptide, and d. detecting the captured GPVI polypeptide or peptide with the second monoclonal antibody, wherein the first and second monoclonal antibodies inhibit collagen-induced platelet aggregation at an IC