Patent ID: 7666393
Filing Date: 2010-02-23
Classification: A61K,G01N

Abstract:
1. A method of assessing a therapeutic effect of an antiangiogenic agent in a patient having a disease associated with increased angiogenesis being treated with the agent comprising: a. measuring the level of endothelial progenitor cells in the blood of the patient at time point A; b. administering the antiangiogenic agent to the patient; c. measuring the level of endothelial progenitor cells in the blood of the patient at time point B; and d. determining whether there is a change in the level of endothelial progenitor cells in the blood of the patient from the measurement at point A to the measurement at point B, wherein a decrease in the level of endothelial progenitor cells in the blood of the patient indicates that the antiangiogenic agent is producing the desired therapeutic effect.