Patent ID: 8715648
Filing Date: 2014-05-06
Classification: A61K,A61P

Abstract:
1. A pharmaceutical formulation for treatment or prophylaxis of risk factors for cardiovascular disease (CVD), protection against sudden death in patients with cardiovascular disease, treating an obesity related disorder, preventing weight regain or for weight maintenance, by providing a sustained vasodilatory effect, comprising: a mixture containing omega-3 fatty acids including eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and docosapentaenoic acid (DPA) wherein the weight ratio of EPA:DHA is in the range of 5.7:1-6.3:1, the formulation contains about 90% or more by weight omega-3 fatty acids, and the formulation comprises about 82% by weight EPA, DHA, and DPA; and at least one anti-obesity agent which affects at least one mechanism of action selected from the group consisting of energy expenditure, glycolysis, gluconeogensis, glucogenolysis, lipolysis, fat absorption, fat storage, fat excretion, hunger, satiety, craving mechanisms, appetite, food intake, gastrointestinal motility, and combinations thereof; wherein said pharmaceutical formulation is provided in an effective unit dosage of 3-4 one gram dosage forms per day.