Patent ID: 9028821
Filing Date: 2015-05-12
Classification: A61K,A61P,C07K

Abstract:
1. A method for treating an inflammatory disease, the method comprising: administering an antibody that binds a novel cytokine receptor 10 (NR 10) and has an NR 10-neutralizing activity to a patient with an inflammatory disease; and assessing whether the patient's inflammatory disease is suppressed, wherein the antibody binds to and neutralizes human NR 10 and cynomolgus monkey NR 10, and wherein the inflammatory disease is atopic dermatitis, chronic dermatitis, rheumatism, osteoarthritis, or rheumatoid arthritis, provided that, when the inflammatory disease is atopic dermatitis, the assessment comprises assessing at least one of the following symptoms of atopic dermatitis: (a) pruritus, (b) redness, (c) bleeding, (d) edema, (e) tissue damage, (f) incrustation, and (g) dryness.