Patent ID: 6037359
Filing Date: 2000-03-14
Classification: C07D

Abstract:
A method for the treatment or prevention of arteriosclerosis human, comprising administering to the human an effective amount of an isoxazolidinedione compound of the formula (I) ##STR391## wherein R is a pyridyl, which is optionally substituted by 1 to 3 substituents; or a pyridyl which is condensed with a phenyl, which is optionally substituted by 1 to 3 substituents; or a group of the formula ##STR392## wherein R.sub.1 is a pyridyl, which is optionally substituted by 1 to 3 substituents; or a pyridyl, which is condensed with a phenyl, which is optionally substituted by 1 to 3 substituents; R.sub.2 and R.sub.3 are the same or different and each is a hydrogen atom or a C.sub.1-4 alkyl, and X is an oxygen atom, a sulfur atom or a secondary amino;R.sub.4 is a hydrogen atom or a C.sub.1-4 alkyl;R.sub.5 is a C.sub.1-4 alkyl; andT and Q are each a hydrogen atom or T and Q together form a bond, said substituents being a group selected from hydroxyl, a C.sub.1-4 alkyl and a C.sub.1-4 alkoxyl; ora C.sub.1-4 alkyl and a C.sub.1-4 alkoxyl; ora pharmaceutically acceptable salt thereof.