Patent ID: 8696760
Filing Date: 2014-04-15
Classification: A61F,A61L,A61P,C12N

Abstract:
1. An implantable construct comprising: (a) a first hemispherical matrix and a second hemispherical matrix each having a first surface, a closed end, and an open equatorial border comprising a flanged region, wherein the first matrix and the second matrix are adapted to mate and are shaped to conform to at least a part of a luminal organ when mated, wherein the first matrix, the second matrix, or both, are each adapted to receive a native vessel, and wherein the flanged region of the first matrix is adapted to mate with the flanged region of the second matrix; and (b) a first cell population deposited on or in said first surface of the first matrix and on or in said first surface of the second matrix to form an implantable construct, wherein said first cell population comprises a muscle cell population, said matrices and said cell population forming an implantable construct.