Patent ID: 8580308
Filing Date: 2013-11-12
Classification: A61K,A61P

Abstract:
1. A method of formulating a composition of modafinil comprising the steps of: a) providing a batch of modafinil, wherein the particles in the batch have a distribution of particle diameters; b) separating the particles in the batch of modafinil into at least two discrete lots of modafinil particles, thereby forming at least a first discrete lot and a second discrete lot, wherein the particle size distribution of the modafinil particles in the second discrete lot is different than the particle size distribution of the modafinil particles in the first discrete lot such that at least about 95% of the particles in the first lot and at least about 95% of the particles in the second lot do not overlap in size; c) blending a portion of the first lot with a portion of the second lot; and d) forming a composition of modafinil from the blend of the first lot and the second lot; wherein the proportions of the first discrete lot and the second discrete lot are adjusted so that between about 10% to about 30% by weight of the modafinil particles in the composition have diameters greater than 220 microns.