Patent ID: 6743818
Filing Date: 2004-06-01
Classification: A61P,C07D

Abstract:
A compound selected from those of formula (I): wherein:n represents 0, R1 represents a group selected from hydrogen, hydroxy, cyano, linear or branched (C1-C6)alkoxy, linear or branched (C1-C6)alkoxycarbonyl, carboxy, and NR4R5 wherein R4 and R5, which may be identical or different, represent linear or branched (C1-C6)alkyl, R2 represents a group selected from a group of formula: and â€”Uâ€”Vâ€”Wwherein:T represents cyclohexyl, U represents a bond, N represents a bond, oxygen, or S(O)q wherein q is integer 0 to 2 inclusive, and W represents a group selected from aryl, aryl-(C1-C6)alkyl in which alkyl may be linear or branched, cyclohexyl, and cyclohexyl-(C1-C6)alkyl in which alkyl may be linear or branched, and R3 represents heteroaryl, its isomers, and also addition salts thereof with a pharmaceutically-acceptable acid or base, wherein:aryl represents phenyl which may be, optionally substituted by one or more, identical or different, groups selected from halogen, linear or branched (C1-C6)alkyl, hydroxy, linear or branched (C1-C6)alkoxy, nitro, cyano, linear or branched (C1-C6)trihaloalkyl, amino, monoalkylamino, di-(C1-C6)alkylamino in which alkyl may be linear or branched, (C1-C6)trihaloalkoxy in which alkoxy may be linear or branched, amino-(C1-C6)alkylaminocarbonyl (nitrogen of each of amino moieties optionally being substituted by, identical or different, linear or branched (C1-C6)alkyl), pyridyl, pyridyloxy, and pyridyloxymethyl, the latter three groups optionally being substituted by linear or branched (C1-C6)alkyl, heteroaryl is pyridyl optionally substituted by one or more, identical or different, groups selected from the substituents described for aryl defined above.