Patent ID: 8729254
Filing Date: 2014-05-20
Classification: A61K,A61Q,C07H,Y10S

Abstract:
1. A process for preparing at least one 0-acyl derivative mainly in position 6 of glucose chosen from derivatives of formula (Ia) below: R is chosen from linear and branched, saturated and unsaturated hydrocarbon-based chains comprising from 7 to 21 carbon atoms, comprising: (1) preparing a mixed anhydride of formula (II): by reacting a carboxylic acid of formula R—COOH with a trimethylacetic acid halide of formula X—C(O)—C(CH (2) reacting said mixed anhydride formed with glucose; wherein in the compounds of formula (Ia), the ratio of the number of ester functional groups in position 6 to the total number of ester functional groups, per glucose molecule, ranges from 55% to 95%.