Patent ID: 6558903
Filing Date: 2003-05-06
Classification: A61K,C07K,C12N,C12Q

Abstract:
An isolated nucleic acid molecule selected from the group consisting of:a) a nucleic acid molecule comprising a nucleotide sequence that encodes a polypeptide having a kinase protein activity and which is at least 85% identical to the nucleotide sequence of SEQ ID NO:1, to nucleotides 191-1156 of SEQ ID NO:1, or a complement thereof; b) a nucleic acid molecule comprising a fragment of at least 325 nucleotides of the nucleotide sequence of SEQ ID NO:1 or a complement thereof, wherein said fragment encodes a polypeptide having a kinase protein activity; c) a nucleic acid molecule which encodes a polypeptide comprising the amino acid sequence of SEQ ID NO:2; d) a nucleic acid molecule which encodes a fragment of a polypeptide comprising the amino acid sequence of SEQ ID NO:2; wherein the fragment has a kinase protein activity and comprises at least 75 contiguous amino acids of SEQ ID NO:2; and e) a nucleic acid molecule which encodes a variant of the polypeptide comprising the amino acid sequence of SEQ ID NO:2, said variant having a kinase protein activity, wherein the nucleic acid molecule hybridizes to a nucleic acid molecule comprising SEQ ID NO:1, nucleotides 191-1156 of SEQ ID NO:1, or a complement thereof under stringent conditions, said stringent conditions comprising hybridization in 6Ã—SSC at 42Â° C., followed by washing with 1Ã—SSC at 55Â° C.