Patent ID: 8945832
Filing Date: 2015-02-03
Classification: A61P,C12Q,G01N

Abstract:
1. Method of treatment of a mammalian subject in need thereof, wherein said subject has a breast cancer, comprising the steps of: a) providing a sample earlier obtained from said subject; b) evaluating the amount of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) protein or HMGCR mRNA present in at least part of said sample, and determining a sample value corresponding to said amount; c) comparing the sample value obtained in step b) with a reference value; and, if said sample value is higher than said reference value, d) treating said subject with an endocrine treatment regimen, wherein said endocrine treatment is a selective estrogen receptor modulator (SERM) treatment.