Patent ID: 8198041
Filing Date: 2012-06-12
Classification: A61P,C07J,C12N,C12P

Abstract:
1. A microbial method of producing Δ 1,4 -Tibolone (C 21 H 26 O 2 ), 10β-Hydroxy-Δ 4 -tibolone (C 21 H 28 O 3 ), 11α,15β-Dihydroxytibolone (C 21 H 28 O 4 ) and 11α,15β-Dihydroxy-Δ 5 -tibolone (C 21 H 28 O 4 ) by growing Cunninghamella elegans (ATCC 10028b) in a nutrient media containing tibolone.