Patent ID: 6730266
Filing Date: 2004-05-04
Classification: A61M

Abstract:
A method for treating inflammatory mediator related diseases including sepsis, septic shock, systemic inflammatory response syndrome, multiple organ system dysfunction syndrome, and multiple organ system failure in a mammal comprising:pumping blood from the mammal using a blood pump; transferring the blood from the blood pump to a hemofilter; removing an ultrafiltrate from the blood using the hemofilter to create a filtered blood stream and an ultrafiltrate stream; transferring the ultrafiltrate stream from the hemofilter to an adsorptive device containing at least one fixed adsorbent material; selectively removing at least one inflammatory mediator which causes an inflammatory mediator related disease from the ultrafiltrate stream using the adsorbent material to create a post adsorption ultrafiltrate stream; combining at least a portion of the post adsorption ultrafiltrate stream with the filtered blood stream and returning the combined post adsorption ultrafiltrate stream and the filtered blood stream to the mammal; and transferring a portion of the post adsorption ultrafiltrate stream which is not returned to the mammal to a waste reservoir.