Patent ID: 8153131
Filing Date: 2012-04-10
Classification: A61K,A61P,C07K,Y02A

Abstract:
1. An isolated antibody that specifically binds a human HMGB1 polypeptide, wherein the antibody comprises: a) a light chain variable region comprising SEQ ID NO:13, and a heavy chain variable region; or b) a heavy chain variable region comprising SEQ ID NO:15, and a light chain variable region; or c) a light chain variable region comprising the 3 CDRs of the light chain variable region of SEQ ID NO:13, and a heavy chain variable region comprising the 3 CDRs of the heavy chain variable region of SEQ ID NO:15; or d) a light chain variable region comprising SEQ ID NO:13 and a heavy chain variable region comprising SEQ ID NO:15.