Patent ID: 6607658
Filing Date: 2003-08-19
Classification: A61B,C12Q,G01N

Abstract:
A device for determining the concentration of glucose in blood from a patient, comprising:a piercing member adapted to pierce and retract from a site on the patient to cause blood to flow therefrom; a sensor positioned adjacent to the site on the patient and adapted to receive the blood flowing from the site to generate an electrical signal indicative of the concentration of glucose in the blood, the sensor comprising a working electrode comprising a glucose-responsive enzyme and a redox mediator, and a counter electrode, wherein the working and counter electrodes are each positioned to contact a sample in a measurement zone having a volume of less than about 1 &mgr;l; and a glucose monitor operatively connected to the sensor and adapted to measure the signal generated by the sensor, wherein the sensor is adapted so that a signal generated by electrolysis of a buffer solution with 10 mM glucose is at least about nine times greater than a signal generated by electrolysis of a buffer solution with no glucose by the sensor.