Patent ID: 6541606
Filing Date: 2003-04-01
Classification: A61K,A61P,C07K,C12N,C12Y,Y10S

Abstract:
A formulation comprising:a) a batch-processed protein crystal, wherein said protein is selected from the group consisting of hydrolases, lipases, bacterial proteins and human growth hormone; and b) an excipient, wherein said excipierit and said protein crystal are in a ratio between 0.01:99.99 and 30:70 (W/W); wherein said formulation has at least a 59 fold greater shelf life when stored at 40Â° C. and 75% humidity than a nonformulated form of said protein crystal when stored at 40Â° C. and 75% humidity, as measured by the time required for the specific activity of the protein to decrease by 50% (TÂ½).