Patent ID: 6034088
Filing Date: 2000-03-07
Classification: A61L,C08G,Y10S

Abstract:
A method of inhibiting the formation/reformation of internal adhesions comprising applying to one or more tissues of a mammal in need thereof an aqueous composition comprising:(1) an effective amount of pentoxifylline(2) about 60% to about 90% by weight of water, and;(3) about 5% to about 35% by weight of a polyoxyalkylene block copolymer of the formula(Y[(A).sub.n --E--H).sub.x (I)wherein A is a polyoxyalkylene moiety having an oxygen/carbon atom ratio of less than 0.5, x is at least 1, Y is derived from water or an organic compound containing x reactive hydrogen atoms, E is a polyoxyethylene moiety, n has a value such that the minimum molecular weight of A is between about 500 and about 900, as determined by the hydroxyl number of an intermediate of the formulaY((A)--H).sub.x (II)and the total average molecular weight of the polyoxyalkylene block copolymer is at least about 5000.