Patent ID: 8454934
Filing Date: 2013-06-04
Classification: A61K,A61P,Y02A

Abstract:
1. A chelation structure, comprising: a backbone structured as R bonding structures (B) each covalently bonded to a corresponding monomeric backbone unit A in a form of A-B, wherein A-B is structured as at least one water-soluble polymer structure (P), wherein each polymer structure P is covalently coupled to the corresponding monomeric backbone unit A by a corresponding bonding structure (B at least one chelator (L), wherein each chelator L is covalently coupled to the corresponding monomeric backbone unit A by a corresponding bonding structure (B wherein R wherein for each monomeric unit, R wherein for each polymer side chain, P is independently selected from the group consisting of a poly(ethylene glycol) (PEG) structure, a poly(propylene glycol) group, a poly(acrylamide) group, a N-substituted polyacrylamides group, a carbohydrate polymer group, an oligosaccharide group, a polyvinyl alcohol group, a polyglycerol group, and a polyvinylpyrolidone group; and wherein the at least one polymer structure is a plurality of polymer structures; wherein for each chelator side chain, the chelator L has a log stability constant K wherein the plurality of polymer structures comprises the PEG structure having a form of R