Patent ID: 6337314
Filing Date: 2002-01-08
Classification: A01N,A61K,A61L,A61P,C07K,Y02A,Y10S

Abstract:
A method for killing bacteria or fungi, wherein said bacteria or fungi are selected from the group consisting of gram-negative bacteria, gram-positive bacteria and yeast, comprising contacting the bacteria or fungi with a bacterial or fungal cell killing effective amount of a fragment of mammalian hemoglobin protein, selected from the group consisting of mammalian heme-free hemoglobin &agr; chain, a mammalian heme-free hemoglobin &bgr; chain, a mammalian hemoglobin &agr;-3 fragment, a mammalian hemoglobin &bgr;-2 fragment, a peptide which is SEQ ID NO:3, a peptide which is SEQ ID NO:2, a peptide which is SEQ ID NO:5, a peptide which is SEQ ID NO:6; said mammalian hemoglobin protein fragment retaining bacterial or fungal killing function, wherein said contacting is for a time and under conditions effective to kill bacteria or fungi.