Patent ID: 7060446
Filing Date: 2006-06-13
Classification: B01F,B01J,B01L,G01N

Abstract:
1. A microfabricated binding assay device comprising: (1) an internal surface defining a microfabricated conduit, (2) the microfabricated conduit having at least one inlet for introducing liquid and a mixture comprising a test compound and a receptor or a test compound, a receptor and a ligand, (3) means for forming a diffusion region within the microfabricated conduit which extends across the entire cross-section of the conduit, wherein the diffusion region contains the mixture; (4) an outlet for exiting liquid from the microfabricated conduit, such that in use the ability of the test compound to prevent the binding of the ligand, if present, to the receptor, or the ability of the test compound to bind the receptor, is determined by reference to the diffusion of the test compound, the receptor or the ligand out of the diffusion region.