Patent ID: 7205302
Filing Date: 2007-04-17
Classification: A61K,A61P,C07D

Abstract:
1. A pharmaceutical composition comprising a heterocyclic compound represented by the following general formula (1) or a salt thereof as an active ingredient: wherein R 1 and R 2 are the same or different and each represents an optionally substituted aryl, and the substituents are the same or different and 1 to 3 substituents are selected from the group consisting of halogen, alkyl, haloalkyl, arylalkyl, alkoxy, alkylthio, alkoxyalkyl, alkylsulfonyl, hydroxy, amino, monoalkylamino, dialkylamino, carboxy, cyano and nitro, Y represents N or N→O, Z represents CR A represents NR D represents alkylene or alkenylene which are optionally substituted with hydroxy, or A and D are combined with each other to form a divalent group represented by the following formula (2): r represents an integer of 0 to 2, q represents an integer of 2 to 3, and t represents an integer of 0 to 4, E represents phenylene or single bond, or D and E are combined with each other to form a divalent group represented by the following formula (3): u represents an integer of 0 to 2, and v represents 0 or 1, G represents O, S, SO, SO R Q represents carboxy, alkoxycarbonyl, tetrazolyl, carbamoyl, monoalkylcarbamoyl, dialkylcarbamoyl, or a group represented by the following formula (22): R and a pharmaceutically acceptable carrier.