Patent ID: 6423320
Filing Date: 2002-07-23
Classification: A61K,A61P,Y10S

Abstract:
A method for prophylaxis and/or treatment of a type I allergic disease which comprises administering to a type I allergic patient a composition comprising an effective amount of an isolated capsule component of a microorganism selected from the group consisting of Klebsiella oxytoca and Klebsiella pneumoniae, or a molecule retained by an ultrafiltration membrane having a cut off molecular weight of 1Ã—105 daltons, said molecule produced by the treatment of said capsule component with an acid, a base or a reducing agent and wherein said isolated capsule component is a polysaccharide having a repeating unit of the formula: wherein L-Rha is an L-rhamnose residue, D-Gal is a D-galactose residue, D-Glc is a D-glucose residue, and D-GlcUA is a D-glucuronic acid residue, and the numerals indicate the positions of the glycoside linkages, said repeating unit being composed of respective monosaccharide residues in molar proportions of 0.8 to 1.2 for