Patent ID: 6323319
Filing Date: 2001-11-27
Classification: A61K,C07K

Abstract:
A method for preparing chicken sternal cartilage-derived material comprising hydrolyzed collagen type II powder, comprising the following steps:(a) cutting fresh chicken sternal cartilage to within not less than about 2 mm of the bone;(b) suspending said cartilage in an aqueous solution;(c) treating said cartilage with a proteolytic enzyme to form a hydrolysate, said proteolytic enzyme being capable of hydrolyzing collagen type II to fragments having an average molecular weight of between 1,500 and 2,500 daltons;(d) sterilizing said hydrolysate;(e) filtering said hydrolysate;(f) concentrating said hydrolysate;(g) drying said hydrolysate to form a powder enriched in collagen type II; and(h) isolating said powder enriched in collagen type II.