Patent ID: 6479470
Filing Date: 2002-11-12
Classification: A61P,C07C,C07F

Abstract:
A compound represented by generalized structure 1: whereinX is selected from the group consisting of â€”C(O)â€”, â€”C(S)â€”, â€”P(O)(N(R)2)â€”, â€”P(NR)(OR)â€”, â€”P(NR)(N(R)2)â€”, O, S, â€”S(O)â€”, â€”S(O)2â€”, Se, â€”Se(O)â€”, â€”Se(O)2â€”, â€”C(R)(OR)â€”, â€”C(R)(SR)â€”, â€”C(NR)â€”, â€”NR(O)â€”, and â€”N(OR)â€”; Y is selected, independently for each occurrence, from the group consisting of (C(R)2)n, (NR)n, (PR)n, and a bond; Z is selected, independently for each occurrence, from the group consisting of C(R), C(N(R)2), C(NHacyl), N, and P; W is selected, independently for each occurrence, from the group consisting of (C(R)2)m, (NR)m, (PR)m, and a bond; G is selected, independently for each occurrence, from the group consisting of â€”COOH, â€”C(O)NHOH, â€”C(O)NH2, â€”C(S)SH, â€”SO3H, â€”SO2H, â€”SOH, â€”SeO3H, â€”SeO2H, â€”SeOH, â€”S(O)2NH2, â€”P(O)(OH)2, and â€”P(OH)2; R is selected, independently for each occurrence, from the group consisting of H, alkyl, heteroalkyl, aryl, heteroaryl, and aralkyl; or R is a negative charge for instances of R bonded to a heteroatom; and m and n are integers selected, independently for each occurrence, from the range 0 to 3 inclusive.