Patent ID: 8557163
Filing Date: 2013-10-15
Classification: A61L,B33Y

Abstract:
1. A method of fabricating a three dimensional scaffold suitable for tissue-engineering having a controlled microporous structure and a controlled macroporous structure using cryogenic prototyping comprising: a) dispensing a first polymer solution in one direction into a reaction chamber to form a first lane; b) dispensing a second polymer solution into said reaction chamber to form a second lane; c) dispensing further polymer solutions into said reaction chamber by repeating steps a) and b) to form further lanes in a first plane; d) repeating steps a) to c) to form further lanes in a next plane, e) repeating step d) to form a three-dimensional scaffold comprising different planes of lanes formed by said polymer solutions; f) removing said solvents from said three-dimensional scaffold so obtained, wherein said method further comprises using different time intervals between dispensing of said different planes into said reaction chamber, and further comprises dispensing lanes, threads or drops forming a subsequent plane into said reaction chamber only after the lanes, threads or drops forming the previous plane are frozen.