Patent ID: 8889723
Filing Date: 2014-11-18
Classification: A61P,C07D

Abstract:
1. A method of treating inner ear hardness of hearing and restoring hearing of humans and animals after damage and loss of sensory hair cells in an organ of Corti based on regeneration biology, comprising administering a therapeutically effective amount of a compound comprising aminoalkyloxazole and aminoalkylthiazole carboxylic acid amides of formula (1) wherein X represents oxygen (O) or sulfur (S), R R R or a pharmaceutically acceptable salt, a stereoisomer, a stereoisomer mixture, a tautomer or a prodrug compound thereof, directly or indirectly to damaged tissue structures in a cochlea, optionally, by transtympanal injection into a middle ear, by application to a round or oval window of an inner ear or by injection into the inner ear.