Patent ID: 6495675
Filing Date: 2002-12-17
Classification: A61K,A61P,C07H,C12N

Abstract:
A capped oligonucleotide of the formula (I):m7GpppXpYâ€ƒâ€ƒ(I) wherein ppp is a triphopshate bridge, p is a monophosphate bridge, m7G is a 7-methylguanosine group binding at the 5â€² end thereof to said ppp, X is a 2â€²-O-methyl guanosine group or guanosine group, said 2â€²-O-methyl guanosine group or said guanosine group binds at the 5â€² end thereof to said ppp, and at the 3â€² end thereof to said p, and Y is an oligoribonucleotide moiety consisting of the base sequence of SEQ ID NO: 4.