Patent ID: 8076312
Filing Date: 2011-12-13
Classification: A61K

Abstract:
1. A method of decreasing the number or frequency of relapse episodes or reducing the incidence of disease-related symptoms of asthma in a subject, comprising the step of administering to a subject a compound represented by the structure of the general formula I: wherein R R Y is either nothing or a spacer group ranging in length from 2 to 30 atoms; X is a glycosaminoglycan; and 2 to n is a number 2 to 200; wherein said spacer comprises —CO-alkylene-NH—, —CO-alkylene-CO— or a combination thereof and said spacer is linked to a hydroxyl or carboxylic acid of said glycosaminoglycan; and wherein if Y is nothing the phosphatidylethanolamine is directly linked to glycosaminoglycane via a carboxylic group.