Patent ID: 7803411
Filing Date: 2010-09-28
Classification: A61K,A61P,C07G,C12N,C12R

Abstract:
1. A physiologically active substance NK13650P3 having the following physicochemical properties or a pharmacologically acceptable salt thereof: 1) colour and shape: pale yellow powder; 2) molecular formula: C 3) molecular weight: 723; 4) hydrogen nuclear magnetic resonance spectrum: a spectrum measured at 600 MHz in heavy water is as follows: chemical shift value δppm: 7.05 (1H, s), 7.00 (1H, d), 6.96 (1H, d), 6.83 (1H, s), 4.43-4.48 (2H, m), 4.28 (1H, m), 4.15 (2H, m), 3.21 (2H, m), 2.58-2.78 (6H, m), 2.34 (1H, m), 2.18 (1H, m), 1.99 (1H, m), 1.88 (1H, m), 1.71 (1H, m), 1.63 (1H, m) 5) carbon nuclear magnetic resonance spectrum: a spectrum measured at 150 MHz in heavy water is as follows: chemical shift value δppm: 181.5(s), 181.4(s), 179.9(s), 179.2(s), 174.5(s), 174.3(s), 171.5(s), 165.4(s), 159.7(s), 149.5(s), 149.2(s), 127.8(s), 126.2(d), 126.1(s), 122.0(d), 119.0(d), 117.1(d), 77.7(s), 68.8(t), 57.8(d), 55.1(d), 54.2(d), 47.4(t), 47.0(t), 43.4(t), 40.7(t), 34.2(t), 33.9(t), 25.9(t) 6) ultraviolet radiation spectrum: a spectrum measured in an aqueous solution is as follows: λ 7) solubility: easily soluble to water and insoluble to methanol, acetone, ethyl acetate, chloroform, and dimethyl sulfoxide; and 8) color reaction: positive for phosphomolybdic acid-sulfuric acid and Rydon-Smith reagent.