Patent ID: 6210423
Filing Date: 2001-04-03
Classification: A61B,A61F

Abstract:
A method for bone marrow-shielded chemotherapeutic treatment of a patient in need thereof, said method comprising:applying pressure to at least one body part of the patient to temporarily occlude arterial flow to the bone marrow within the proximal humerus and/or proximal femur while blood circulation through the remainder of the body is maintained,administering to the blood circulation in the remainder of the body an effective amount of at least one myelosuppresive chemotherapeutic agent while the arterial flow through the at least one body part is occluded and so that the myelosuppresive effect of the agent is substantially dissipated within the maximum safe period for the occlusion of the arterial flow, andremoving the pressure to restore blood circulation to the bone marrow when the effect has substantially dissipated and within the maximum safe period,wherein a tumor located in the remainder of the body is treated by the at least one chemotherapeutic agent without destruction of a substantial portion of the bone marrow in the at least one body part, and without general anesthesia.