Patent ID: 8669361
Filing Date: 2014-03-11
Classification: A61P,C07D

Abstract:
1. A method of treating cancer comprising administering a therapeutically effective amount of a compound to a patient wherein the compound is selected from Formula I: and stereoisomers, geometric isomers, tautomers, or pharmaceutically acceptable salts thereof, wherein: R R X is selected from the structures: where the wavy line indicates the site of attachment; R R R R where alkyl, alkenyl, alkynyl, alkylene, carbocyclyl, heterocyclyl, aryl, and heteroaryl are optionally substituted with one or more groups independently selected from F, Cl, Br, I, —CH wherein the cancer is selected from multiple myeloma, leukemia, lymphoma, prostate cancer, pancreatic cancer, and hepatocellular carcinoma.