Patent ID: 6211234
Filing Date: 2001-04-03
Classification: A61P,C07C,C07D,C07F

Abstract:
A compound of formula I ##STR22##whereinR.sup.1 is --CN;R.sup.2 is aryl lower alkoxy or aryl lower alkylthio;R.sup.3 is hydroxy, alkoxy, aryloxy, cycloalkyl(lower alkyl)oxy, cycloalkenyl(lower alkyl)oxy, aryl lower alkoxy, aryl lower alkylthio, or aralkynyl;R.sup.4 is --Y--CH(R.sup.15)(alkyl or alkenyl)R.sup.16 ;R.sup.5 is alkyl, alkenyl or halo;R.sup.15 is aryl;R.sup.16 is carboxy;Y is oxygen or carbonyl; andm, n and p are independently zero or 1, and o is 1;with the proviso that at least one of m and n is 1,or a pharmaceutically acceptable salt, or prodrug thereof.