Patent ID: 6548242
Filing Date: 2003-04-15
Classification: A61K,A61L,C12N

Abstract:
A process for inactivating an extracellular or intracellular virus which may be present in a biological composition, said biological composition comprising at least one of a cell-containing biological composition and a biological fluid composition, said process comprising subjecting said biological composition to a virucidally effective amount of artificial irradiation, in the presence of (a) a mixture of at least one quencher compound that quenches type I photodynamic reactions and at least one quencher compound that quenches type II photodynamic reactions, or (b) a quencher compound that quenches both type I and type II reactions, or (c) a mixture of a quencher compound that quenches both type 1 and type II reactions and an additional quencher compound, whereby said quencher compound(s) are present at a concentration effective to substantially maintain, in the case of said cell-containing biological composition, at least 70% of structural integrity of cells in said cell-containing biological composition and in the case of said biological fluid composition, at least 75% of activity of said biological fluid composition.