Patent ID: 6593325
Filing Date: 2003-07-15
Classification: A61P,C07D

Abstract:
A compound of formula IIB, or a pharmaceutically acceptable salt thereof: whereinQ represents the residue of a cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl or phenyl ring; R1 represents C3-7 cycloalkyl, phenyl, furyl, thienyl or pyridinyl, any of which groups may be unsubstituted or substituted with one or more substituents selected from the group consisting of C1-6 alkyl, aryl(C1-6)alkyl, pyridyl(C1-6)alkyl, halogen, halo(C1-6)alkyl, cyano, cyano(C1-6)alkyl, hydroxy, hydroxymethyl, C1-6 alkoxy, C3-7 cycloalkyl(C1-6)alkoxy, C3-7 cycloalkoxy, anino(C1-6)alkyl, di(C1-6)alkylamino(C1-6)alkyl, di(Ci)alkylaminocarbonyl(C1-6)alkyl, N-(C1-6)alkylpiperidinyl, pyrrolidinyl(C1-6)alkyl, piperazinyl(C1-6)alkyl, morpholinyl(C1-6)alkyl, di(C1-6)alkylmorpholinyl(C1-6)alkyl and imidazolyl(C1-6)alkyl; R3 represents hydrogen, methyl or fluoro; and R4 represents methyl or ethyl.