Patent ID: 6576638
Filing Date: 2003-06-10
Classification: A61K,A61P

Abstract:
A method for treating adenocarcinomas comprising the steps of administering to a subject in need of treatment a pharmaceutically effective amount of an antagonists of NK-1 receptors, such antagonists being one or more compounds and corresponding mixtures selected among the compounds having the following characteristics:pA2>6.0 in human and murine tissue; non peptidic heterocyclic structure; antiangiogenetic effects experimentally demonstrated in urogenital tumors, induced by orthotopic implantation of human tumoral cells in immunodeficient rat and mice urogenital tissues, said orthotopic implantation being made by inoculating the rat and mice urogenital tissues with said human tumoral cells and said angiogenetig effects being measured by the reduction of tumoral mass in the urogenital tumors induced by the orthotopic implantation.