Patent ID: 8221446
Filing Date: 2012-07-17
Classification: A61F,A61M

Abstract:
1. An embolic protection device for filtering emboli in a body vessel in which blood flows in a first direction along a blood flow path, the body vessel defining a central longitudinal axis, the device comprising: a filtering body having a lip including a perimeter, the filtering body extending therefrom to a tail having an end face, the filtering body being configured to be folded into a closed state for delivery or retrieval and expanded into an open state for filtering emboli, the filtering body having a first plurality of openings formed therethrough and positioned generally spaced apart from each other and a second plurality of openings formed therethrough and positioned generally spaced apart from each other, the first plurality of openings being located adjacent to the lip, the second plurality of openings being located along the end face of the tail of the filtering body, the end face having a substantially perpendicular orientation that is substantially perpendicular to the first direction of the blood flow, the filtering body providing a flow resistance when the tail is folded, the substantially perpendicular orientation of the end face causing the filtering body to fully open into the open state when placed in the body vessel in the blood flow path, the first plurality of openings each having a first area for maintaining fluid flowpaths through the device and the second plurality of openings each having a second area for filtering emboli in the body vessel, wherein the first area is greater than the second area in both the closed state and the open state, and wherein the first plurality of openings is generally more spaced apart from each other than the second plurality of openings; and a frame connected to the lip for supporting the filtering body, wherein the frame includes a wire formed into a loop that extends around the perimeter of the lip, wherein the frame perpendicularly opens in a radial direction along a plane perpendicular to the central longitudinal axis defining an opened state of the frame; wherein the device further comprises a material promoting biofixation between the filtering body and the body vessel; and wherein the material promoting biofixation includes extracellular matrix material that functions as a remodeling bioscaffold between an outer surface of the filtering body and an inner surface of the body vessel.