Patent ID: 8841080
Filing Date: 2014-09-23
Classification: C07K,G01N

Abstract:
1. A method for determining an amount of partially processed and/or unprocessed Clostridium botulinum neurotoxin A (BoNT/A) in a solution comprising processed and partially processed and/or unprocessed BoNT/A, wherein the partially processed and unprocessed BoNT/A exhibit a linker peptide, comprising the steps of: i) contacting a sample of the solution with a capture antibody which specifically binds to the partially processed and unprocessed BoNT/A under conditions which allow for binding for the antibody to the partially processed and unprocessed BoNT/A, whereby a complex is formed, and ii) determining the amount of the complex formed in step i), whereby the amount of the complex is indicative for the amount of the partially processed and/or unprocessed BoNT/A in the solution;