Patent ID: 6545173
Filing Date: 2003-04-08
Classification: C07C

Abstract:
A process for the preparation of compounds of formula I in which R1 and R2, which may be the same or different, are H, halo, trifluoromethyl, an alkyl group containing 1 to 3 carbon atoms, an alkoxy or alkylthio group containing 1 to 3 carbon atoms, phenyl, or R1 and R2, together with the carbon atoms to which they are attached, form a second benzene ring which may be substituted by one or more substituents selected from halo, an alkyl group containing 1 to 4 carbon atoms, an alkoxy group containing 1 to 4 carbon atoms, or the substituents of the second benzene ring together with the two carbon atoms to which they are attached may form a further benzene ring;said process comprising the reaction of a 1,3-dihalopropane, a compound of formula II â€ƒand a suspension of a base in a substantially dimethyl sulphoxide-free solvent at a temperature of at least 35Â° C.