Patent ID: 7659264
Filing Date: 2010-02-09
Classification: A61P,C07D

Abstract:
1. A compound of the Formula I: wherein: A is C(R B is (C(R R R R R W is O, NR X is C or S; Y is O, (R R J is a bond, C(R V is a bond, C(R Q is selected from: ═C(R T is selected from: ═C(R R R p is 0 to 2q+1, for a substituent with q carbons; m is 0, 1 or 2; s is 1, 2 or 3; “heteroaryl” represents a stable 5- to 7-membered monocyclic- or stable 9- to 10-membered fused bicyclic heterocyclic ring system which contains an aromatic ring, any ring of which may be saturated, partially saturated, or unsaturated, and which consists of carbon atoms and from one to four heteroatoms selected from the group consisting of N, O and S, and wherein the nitrogen and sulfur heteroatoms may optionally be oxidized, and the nitrogen heteroatom may optionally be quaternized, and including any bicyclic group in which any of the above-defined heterocyclic rings is fused to a benzene ring; “heterocycle” or “heterocyclic” represents a stable 5- to 7-membered monocyclic- or stable 8- to 11-membered bicyclic heterocyclic ring system which is either saturated or unsaturated, and which consists of carbon atoms and from one to four heteroatoms selected from the group consisting of N, O and S, and wherein the nitrogen and sulfur heteroatoms may optionally be oxidized, and the nitrogen heteroatom may optionally be quaternized, and including any bicyclic group in which any of the above-defined heterocyclic rings is fused to a benzene ring; or a pharmaceutically acceptable salt or individual diastereomers thereof.