Patent ID: 6413960
Filing Date: 2002-07-02
Classification: A61P,C07D

Abstract:
A method of treating asthma in a subject in need of such treatment, wherein the method comprises administering to the subject an asthma treating-effective amount of a compound having the structure of Formula I: or a pharmaceutically acceptable salt thereof, wherein: R1 is sulfamyl; R2 is haloalkyl; R3 is selected from the group consisting of H and alkyl; and R4 is selected from the group consisting of aryl, cycloalkyl, and cycloalkenyl; wherein R4 is optionally substituted with one or more radicals selected from the group consisting of halo, alkylthio, alkylsulfinyl, alkyl, alkylsulfonyl, cyano, carboxyl, alkoxycarbonyl, amido, N-monoalkylamido, N-monoarylamido, N,N-dialkylamido, N-alkyl-N-arylamido, haloalkyl, hydroxyl, alkoxy, hydroxyalkyl, haloalkoxy, sulfamyl, N-alkylsulfamyl, amino, N-alkylamino, N,N-dialkylamino, heterocyclic, nitro, and acylamino.