Patent ID: 8709767
Filing Date: 2014-04-29
Classification: C12N,C12P,C12Y

Abstract:
1. A process for the enzymatic reduction of a compound (1), wherein the C═C bond of the compound (1) according to formula (1) is stereoselectively hydrogenated in the presence of an enoate-reductase and an oxidizable co-substrate which is a compound having a chemical structure according to formula (1) in a system which is free of NAD(P)H, in which A is a ketone radical (—CRO), an aldehyde radical (—CHO), a carboxyl radical (—COOR), with R =H or optionally substituted C (i) an enoate reductase comprising at least one of the polypeptide sequences SEQ ID NO: 3 or 4; or (ii) an enoate reductase comprising a polypeptide sequence which has at least 95% sequence identity with SEQ ID NO: 3.