Patent ID: 8101712
Filing Date: 2012-01-24
Classification: A61P,C07K

Abstract:
1. A process for purifying an echinocandin-type compound comprising: (a) extracting an echinocandin-type compound from a fermentation broth or from a filtered mycelium obtained from a fermentation broth, with a water-immiscible organic solvent to obtain a two-phase system comprising an aqueous phase and an organic phase or to obtain a water containing organic phase; (b) recovering the echinocandin-type compound; (c) combining the recovered echinocandin-type compound with at least one anti-solvent and a solid carrier to obtain a mixture comprising the anti-solvent and the solid carrier to which a purified echinocandin-type compound is absorbed; (d) separating the mixture to obtain the solid carrier to which a purified echinocandin-type compound is absorbed; and (e) recovering the purified echinocandin-type compound from the separated solid carrier.