Patent ID: 6323220
Filing Date: 2001-11-27
Classification: A61P,C07D

Abstract:
A compound selected from those of formula (I): ##STR23##wherein:A represent pyridine, pyridinium, or piperidine,R.sub.2 represents hydrogen and R.sub.3 represents hydroxy, or R.sub.2 and R.sub.3 together form oxo,R.sub.4 represents substituted phenyl or substituted naphthyl,R.sub.1 represents hydrogen,R.sub.5 represents hydrogen,R.sub.6 represents hydrogen or linear or branched (C.sub.1 -C.sub.6)alkyl, the group R.sub.6 being present or absent depending on the nature of the ring A,5- to 10-membered group containing 1 to 3 hetero atoms selected from oxygen, nitrogen, and sulphur,wherein the substituents on the phenyl and the naphthyl may be the same or different, selected from linear or branched (C.sub.1 -C.sub.6)alkyl, linear or branched (C.sub.1 -C.sub.6)alkoxy, mercapto, linear or branched (C.sub.1 -C.sub.6)alkylthio, amino, linear or branched (C.sub.1 -C.sub.6)alkylamino, di-(C.sub.1 -C.sub.6)alkylamino, in which each alkyl moiety is linear or branched, linear or branched (C.sub.1 -C.sub.6)polyhaloalkyl, hydroxy, and halogen,provided that:when R.sub.2 and R.sub.3 together form oxo and R.sub.6 represents hydrogen or does not exist, then R.sub.4 is substituted naphthyl,when R.sub.2 represents hydrogen and R.sub.3 represents hydroxy and R.sub.6 represents hydrogen or does not exist, then R.sub.4 is substituted naphthyl,the compound of formula (I) may not represent 1-(1,3-benzodioxol-5-yl) 2-(2-pyridinyl)ethanol or 2-(2-pyridinyl)cyclohexanone,its enantiomers and diastereoisomers, and addition salts thereof with a pharmaceutically-acceptable acid or base.