Patent ID: 6716989
Filing Date: 2004-04-06
Classification: C07D

Abstract:
A process for preparing a thioether of the formula X which comprises the steps ofe) reacting an oxime of the formula VI with an alkene of the formula VII in the presence of a hypochlorite, to give the 4,5-dihydroisoxazol of the formula VIII andf) reacting compounds of the formula VIII with a metal thiolate of the formula IX R7â€”Sâˆ’M+â€ƒâ€ƒIX in the presence of a solvent to give the thioether of the formula X, wherein, in the above formulae,R1, R2 are C1-C6-alkyl; R3, R4, R5 are hydrogen or C1-C6-alkyl, or R4 and R5 together form a bond; R6 is Cl or Br.