Patent ID: 9057722
Filing Date: 2015-06-16
Classification: A61M,G01N,Y10T

Abstract:
1. A method, comprising: a) obtaining at least two urine samples from a patient exhibiting at least one symptom of an acute kidney injury, said patient being asymptomatic for a chronic kidney disease, wherein said at least two urine samples comprise a first sample and a subsequent sample, wherein said first sample is collected within one day of initiation of a renal replacement therapy; b) contacting each of said at least two urine samples with a solid support comprising a hyaluronic acid marker system; c) detecting hyaluronic acid in each of said at least two urine samples with a signal generated by said hyaluronic acid marker system; and d) predicting said patient to require long-term dialysis wherein said hyaluronic acid detected in said subsequent sample is elevated as compared to said hyaluronic acid detected in said first sample within sixty days of said first sample.