Patent ID: 6365612
Filing Date: 2002-04-02
Classification: A61P,C07D

Abstract:
A compound of formula I or a pharmaceutically acceptable salt thereof wherein:R1 is a) H, b) NH2, c) NHC1-6 alkyl, d) C1-6 alkenyl, e) OC1-6 alkyl, SC1-6 alkyl, f) (CH2)iâ€”C3-6 cycloalkyl, or g) C1-6 alkyl, optionally substituted with one to three halo; R2 is a) H, b) C1-12 alkyl, optionally substituted with phenyl or CN, or c) C2-12 alkyl substituted with OH, SH, NH2, â€”OC1-6 alkyl, â€”NHC1-6 alkyl, â€”NHCOC1-6 alkyl, â€”NHSO2C1-6 alkyl, â€”S(O)iC1-6 alkyl, or one to three halo; Y is O or S; M is â€”(CH2)nâ€”, wherein n is 1 or 2; and i is 0, 1, or 2.