Patent ID: 6677315
Filing Date: 2004-01-13
Classification: C07H

Abstract:
A method of imaging an organism, comprising the steps of: contacting the organism to be imaged with a compound of the formula: wherein:A=N, C; B=H, hydroxy, halogen, acyl(C1-C6), alkyl alkoxy(C1-C6) D=O, S, NH2; E=H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkoxy, substituted alkoxy, halogen, or any substituent which is readily cleaved in the body to generate H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkoxy, substituted alkoxy, or halogen; at least one of W, X, Y, Z is a label or a label containing moiety having sufficient isotopic activity for imaging and the remainder of W, X, Y, Z=H, hydroxy, halogen, alkyl(C1-C6) substituted alkyl(C1-C6), alkoxy(C1-C6), substituted alkoxy(C1-C6); J=C, S; and K=O, C; and imaging the organism.