Patent ID: 6846625
Filing Date: 2005-01-25
Classification: A01K,C07K,C12N,C12Q,G01N

Abstract:
1. A method for determining whether a biomolecule inhibits growth of cells in vivo, comprising: a) introducing a cell having an exogenous regulable gene encoding a biomolecule into one or more test animals and into one or more control animals, wherein the biomolecule binds a protein target component of the cells; b) regulating expression of the exogenous gene in the test animals to allow production of the biomolecule; and c) monitoring the test animals for growth of the cells wherein observing fewer of the cells or a slower growth rate of the cells in the test animals compared to the number of the cells or growth rate of the cells in the control animals indicates that the biomolecule inhibits growth of cells in vivo.