Patent ID: 8877923
Filing Date: 2014-11-04
Classification: A61P,C07D,C07F

Abstract:
1. A compound of formula II: wherein X is O; Y is O; the ring system represented by A in formula V, below, is a 6 membered aryl group, wherein said aryl group is: wherein the ring system represented by B in formula VI is a five membered unsaturated heterocyclic ring wherein said unsaturated heterocyclic ring is: wherein Z is [C(R 2 ) 2 ] c ; wherein the ring system represented by C in formula VII is a 6 membered heterocyclic aryl, wherein said heterocyclic aryl is: wherein; R each R wherein N(R R is selected from the group consisting of halogen, C R Ar is 5-7 membered carbocyclic aryl or 5-7 membered heterocyclic aryl, each of which is optionally substituted with one or more substituents selected from the group consisting of halogen, trihalomethyl, hydroxyl, SH, OH, NO each R R a in variable R a is 1; b in the variable —(C═X) b is 0; b in the variable R c in the variable [C(R 2 ) 2 ] c is an integer of from 1 to 2; d is 0 or an integer of from 1 to 5; e is an integer of from 1 to 4; f is 0 or an integer of from 1 to 2; g is an integer of from 2 to 5; and further provided said alkyl or aryl radicals may be substituted with one or two halo, hydroxy, lower alkyloxy, lower alkyl amino or cycloalkylamino radicals wherein the cycloalkyl ring can include an enchained oxygen, sulfur or additional nitrogen atom and may be substituted with one or two halo or lower alkyl radicals; or a pharmaceutically acceptable salt thereof.