Patent ID: 8986304
Filing Date: 2015-03-24
Classification: A61B,A61K,A61L,A61P

Abstract:
1. A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus, comprising: injecting a fibrin sealant into the disc, wherein neither the nucleus pulposus nor the annulus fibrosus has been heated, to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, wherein the fibrinogen, the activating compound or both has been reconstituted with a solution containing at least one additive, wherein a corticosteroid is absent from the fibrin sealant injected into the disc, and wherein the injecting occurs by inserting an introducer needle having a tip into an intra-discal space, inserting a second needle or a polymeric catheter through the introducer needle up to but not beyond the tip of the introducer needle, and injecting the fibrinogen through the introducer needle and injecting the activating compound through the second needle or polymeric catheter, or injecting the activating compound through the introducer needle and injecting the fibrinogen through the second needle or polymeric catheter.