Patent ID: 7029677
Filing Date: 2006-04-18
Classification: A61K,A61P,C07K,C12N,C12Y,G01N

Abstract:
1. An in vitro method of killing or inhibiting the growth of CD84Hy1-expressing cells that cause a disease selected from the group consisting of acute myelogenous leukemia, acute myelomonocytic leukemia, acute lymphoblastic leukemia, chronic lymphocytic leukemia, B cell large cell lymphoma, malignant lymphoma, lymphosarcoma cell leukemia, B-cell lymphoma, T-cell lymphoma, acute myeloid leukemia, Hodgkin's disease, autoimmune disorders, and rejection of transplanted tissues or organs, comprising the step of administering a composition to said cells in an amount effective to kill or inhibit the growth of said cells, wherein said composition is an anti-CD84Hy1 antibody that binds to a polypeptide consisting of the amino acid sequence of SEQ ID NO: 2 or amino acid 22 to amino acid 214 of SEQ ID NO: 2.