Patent ID: 6312890
Filing Date: 2001-11-06
Classification: C07K,C12Q,G01N

Abstract:
A method for detecting a mutant allele of a wild-tvDe VHL gene in a subiect suspected of having VHL disease or a disease related to the presence of a mutation in the wildtype VHL gene, said method comprising analyzing a nucleic acid sequence of a subject for the presence of said mutant allele, wherein said analyzing step is performed using a nucleic acid probe, and wherein said probe has a sequence consisting of or said probe has a sequence which is fully complementary to a full length sequence selected from the group consisting of SEQ ID NO: 7 through SEQ ID NO: 11, SEQ ID NO: 16, SEQ ID NO: 23 through SEQ ID NO: 28 and SEQ ID NO: 52 through SEQ ID NO: 53.