Patent ID: 6380180
Filing Date: 2002-04-30
Classification: C07C,C07D

Abstract:
A pharmaceutical composition comprising an effective amount of a compound represented by Formula VIII, whereinA and B, which may be identical or different, represent decamethylene; octamethylene; hexamethylene; pentamethylene; tetramethylene; trimethylene; dimethylene; N,Nâ€²-dimethyl-diamino-methylene; N,Nâ€²-dimethyl-diamino-dimethylene; N,Nâ€²-dimethyl-diamino-trimethylene; (cis and/or trans)-1,5-cyclooctylene; (cis and/or trans)-1,3-dimethylcyclohexane-&agr;,&agr;â€²-diyl; para-xylene-&agr;,&agr;â€²-diyl; meta-xylene-&agr;,&agr;â€²-diyl; 1,3-phenylene; biphenyl-3,3â€²-diyl; 4,4â€²-dimethyl-bibenzyl-&agr;,&agr;â€²-diyl; 4,4â€²-dimethyl-diphenylmethane-&agr;,&agr;â€²-diyl; 4,4â€²-dimethyl-cis/trans-stilbene-&agr;,&agr;â€²-diyl; 2,6-bis(4â€²-methyl-phenyl)pyridine-&agr;,&agr;â€²-diyl; 3,3â€²dimethyl-biphenyl-&agr;,&agr;â€²-diyl; or 2,7-dimethyl-9H-fluorene-&agr;,&agr;1-diyl; X represents hydrogen, halogen, trifluoromethyl, cyano, alkoxy, alkyl, phenyl or benzyl, which phenyl or benzyl may optionally be substituted one or more times with substituents selected among halogen, trifluoromethyl, and alkyl; and Y represents a halide or a pharmaceutically-acceptable addition salt thereof, together with at least one pharmaceutically-acceptable carrier or diluent.