Patent ID: 6956042
Filing Date: 2005-10-18
Classification: A61P,C07D

Abstract:
1. A diazaspiro nonane compound having the following formula: and pharmaceutically acceptable salts thereof, wherein Q u, v, w and x are individually 0, 1, 2, 3 or 4, preferably 0, 1, 2 or 3, and the values of u, v, w and x are selected such that the ring is a diazaspiro nonane, R is hydrogen, lower alkyl, acyl, alkoxycarbonyl or aryloxycarbonyl, Z is, individually, selected from the group consisting of hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, alkylaryl, substituted alkylaryl, arylalkyl and substituted arylalkyl; Cy is a six membered ring of the formula: where one of X, X′, X″, X′″ and X″″ is nitrogen, and the others are carbon bonded to a substituent species, wherein “substituent species” are, individually, selected from the group consisting of hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, alkylaryl, substituted alkylaryl, arylalkyl, substituted arylalkyl, halo, —OR′, —NR′R″, —CF where R′ and R″ are individually hydrogen, C wherein the term “substituted” as applied to alkyl, aryl, cycloalkyl and the like refers to the substituents described above, starting with halo and ending with —NR′SO