Patent ID: 8877035
Filing Date: 2014-11-04
Classification: A61B,C12Q,G01N

Abstract:
1. A method of reducing bias attributable to mediator background in a determined concentration of an analyte in a sample comprising: generating a measurable species from a mediator, the concentration of the measurable species responsive to a concentration of an analyte in a sample; applying an input signal to the sample, the input signal comprising at least 3 duty cycles within 180 seconds and each duty cycle comprising an excitation and a relaxation, measuring an output signal from at least one amperometric excitation of the at least 3 duty cycles, determining the concentration of the analyte in the sample having reduced bias attributable to mediator background in response to the measured output signal, where the determined concentration is responsive to a rate at which the measurable species is oxidized or reduced by the input signal.