Patent ID: 6639107
Filing Date: 2003-10-28
Classification: C07C

Abstract:
A compound of the formula: whereinR1, R2, and R3 each independently represent hydrogen, halogen, CF3, OCF3, CN, NO2, NH2, (1-6C)alkyl, (1-6C)alkoxy, â€”(CH2)nNHSO2R5, â€”(CH2)nNHC(&boxH;O)R5, â€”SO2R5, â€”C(&boxH;O)R6, â€”CH&boxH;CHCO2R7, heterocycle, or phenyl which is unsubstituted or substituted by one, two, or three substituents selected from the group consisting of halogen, CF3, OCF3, CN, NO2, NH2, (1-6C)alkyl, (1-6C)alkoxy, â€”(CH2)nNHSO2R5, â€”(CH2)nNHC(&boxH;O) R5, â€”SO2R5, â€”C(&boxH;O)R6, â€”C(&boxH;O)NR10R11, â€”SO2NR10R11, or â€”CH&boxH;CHCO2R7; R4 represents (1-6C)alkyl, (2-6C)alkenyl, or NR8R9; R5 represents (1-6C)alkyl, CF3, or phenyl which is unsubstituted or substituted by one, two, or three substituents selected from the group consisting of halogen, CF3, CN, NO2, NH2, (1-6C)alkyl, or (1-6C)alkoxy; R6 represents (1-4C)alkyl or phenyl; R7 represents hydrogen or (1-4C)alkyl; R8 and R9 each independently represent hydrogen or (1-4C)alkyl; R10 and R11 each independently represent hydrogen or (1-4C)alkyl; and n is 0, 1, 2, 3, or 4; or a pharmaceutically acceptable salt thereof.