Patent ID: 6174546
Filing Date: 2001-01-16
Classification: A61K,C08F,C08L,C09J

Abstract:
A pressure sensitive adhesive drug delivery composition for use in the transdermal administration of a pharmacologically active agent comprised of a homogeneous admixture of a hydrophilic macromer reinforced copolymer and a pharmacologically active agent, said copolymer comprising the crosslinked reaction product of:(1) at least one A monomer consisting of a monomeric (meth)acrylic acid ester of a non-tertiary alcohol, said alcohol having from 1 to 30 carbon atoms, wherein at least about 30 percent by weight of said A monomer consists of a monomeric (meth)acrylic acid ester of a non-tertiary alcohol having at least 12 carbon atoms, and said at least one A monomer exhibiting an average number of carbon atoms in the alcohol portion of the total (meth)acrylic acid esters of at least 10,(2) optionally at least one B monomer,(3) optionally a polymeric graft moiety C having a T.sub.g greater than 20.degree. C., and(4) a graft macromer D containing hydrophilic repeat units.