Patent ID: 8510082
Filing Date: 2013-08-13
Classification: G01J,G01N

Abstract:
1. An optical interrogation system for interrogating a label-independent biosensor, the optical interrogation system comprising: a launch system that is arranged to emit an optical beam towards a biosensor; a receive system that is arranged to collect an optical beam from the biosensor and then to output a signal which is representative of the collected optical beam; a processor that is arranged to reduce pixelation oscillations in an optical resonance of the signal by oversampling at least a portion of the optical resonance, smoothing the optical resonance and calculating a resonance location or centroid that is based on the smoothed-oversampled optical resonance; and the processor is further arranged to monitor a biological event or a biochemical event on a top surface of the biosensor by sensing a shift between one calculated resonance location or centroid based on one smoothed-oversampled optical resonance and another calculated resonance location or centroid based on another smoothed-oversampled optical resonance.