Patent ID: 9161967
Filing Date: 2015-10-20
Classification: A61K,A61L,A61P

Abstract:
1. A method for increasing bone density in a vertebral body in an individual comprising: applying a composition to the vertebral body, wherein the composition consists of a biocompatible matrix having incorporated therein a solution consisting of platelet derived growth factor (PDGF) at a concentration in a range of about 0.1 mg/ml to about 1.0 mg/ml in a buffer, wherein the biocompatible matrix consists of (i) particles of a porous calcium phosphate in a range of about 100 μm to about 5 mm in size or (ii) (a) particles of a porous calcium phosphate in a range of about 100 μm to about 5 mm in size and (b) collagen, and wherein the calcium phosphate comprises interconnected pores.