Patent ID: 7799534
Filing Date: 2010-09-21
Classification: C12Q,G01N

Abstract:
1. A material comprising a solid support having immobilized thereon a chemiluminescent compound comprising a chemiluminescent moiety and a linking moiety and wherein the chemiluminescent moiety is selected from acridan esters, acridan thioesters, acridan sulfonamides, acridan ketenedithioacetal compounds, acridan compounds of the formula: wherein R 1 is selected from alkyl, alkenyl, alkynyl, aryl, and aralkyl groups of 1-20 carbon atoms any of which can be substituted with 1-3 groups selected from carbonyl groups, carboxyl groups, tri(C 1 -C 8 alkyl)silyl groups, a SO 3 − group, a OSO 3 − [ 2 ] group, glycosyl groups, a PO 3 − group, a OPO 3 −2 group, halogen atoms, a hydroxyl group, a thiol group, amino groups, quaternary ammonium groups, or quaternary phosphonium groups, wherein X is selected from C 1 -C 8 alkyl, aryl, aralkyl groups, alkyl or aryl carboxyl groups having from 1-20 carbon atoms, tri(C 1 -C 8 alkyl)silyl groups, a SO 3 − group, glycosyl groups and phosphoryl groups of the formula PO(OR′)(OR″) wherein R′ and R″ are independently selected from C 1 -C 8 alkyl, cyanoalkyl, aryl and aralkyl groups, trialkylsilyl groups, alkali metal cations, alkaline earth cations, ammonium and trialkylphosphonium cations, wherein Z 1 is selected from O and S atoms, wherein R 6 is selected from substituted or unsubstituted C 1 -C 4 alkyl, phenyl, benzyl, alkoxyalkyl and carboxyalkyl groups, wherein 0 or 1 or 2 of the substituents R 7-14 are selected from alkyl, alkoxy, hydroxy, and halogen and the remaining of R 7-14 are hydrogen.