Patent ID: 6994990
Filing Date: 2006-02-07
Classification: A61K,A61P,C07K,C12N

Abstract:
1. A method for producing a hedgehog protein esterified with a fatty acid having from 14 to 20 carbon atoms comprising: a) providing an insect cell in a medium, said medium and said insect cell being capable upon fermentation of producing a fatty acid having from 14 to 20 carbon atoms, said insect cell containing a baculovirus vector having a gene inserted therein capable of expressing a hedgehog protein; b) fermenting said insect cell in said medium for a period of 30 hours or less to produce the fatty acid and express the hedgehog protein esterified with said fatty acid; and c) isolating said esterified hedgehog protein from the protein produced during said fermentation.