Patent ID: 9017965
Filing Date: 2015-04-28
Classification: C12N

Abstract:
1. A recombinant nucleic acid comprising a hybrid 3′ untranslated region (3′UTR) that comprises a first and a second nucleic acid region, wherein (a) said first region is a 3′ untranslated region (3′UTR) of a stable eukaryotic mRNA of eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) or is part of the 3′UTR of EEF1A1 mRNA, (b) said first region does not contain a polyadenylation signal, (c) said second region is derived from the downstream end of an 3′ untranslated region of another or the same stable eukaryotic mRNA as in (a), and (d) said second region contains a polyadenylation signal, wherein said recombinant nucleic acid has the sequence of SEQ ID NO:3.