Patent ID: 7235637
Filing Date: 2007-06-26
Classification: A61P,C07K

Abstract:
1. An isolated polypeptide selected from the group consisting of: (a) a polypeptide comprising the polypeptide of SEQ ID NO:2; (b) a polypeptide comprising a polypeptide that is at least 98% identical to the polypeptide of SEQ ID NO:2; and (c) a fragment of a polypeptide of (a) or (b), wherein said fragment has an amino terminus selected from the group consisting of amino acids 1 through 5, and a carboxy terminus selected from the group consisting of amino acids 153 through 157, of SEQ ID NO:2; wherein the polypeptide or a fragment thereof activates a signaling molecule selected from the group consisting of p38 MAP kinase and Stress-Activated Protein Kinase (SAPK/JNK).