Patent ID: 6251868
Filing Date: 2001-06-26
Classification: A61K,A61P

Abstract:
A method for killing human immunodeficiency virus (HIV)-infected T-lymphocytes or inactivating infectious HIV particles consisting of administering to a mammal infected with HIV a therapeutically effective amount of .gamma.-L-glutamyl-L-cysteine ester of formula I ##STR4##for a time and under conditions effective to kill HIV-infected T-Iymphocytes or inactivate infectious HIV particles; wherein R is a straight chain, branched or cyclic hydrocarbon group having 1-10 carbon atoms, or a straight chain or branched hydrocarbon group having 1-5 carbon atoms substituted with an aromatic group; or the oxidized dimer obtained by dehydrogenation between two .gamma.-L-glutamyl-L-cysteine esters having formula (I).