Patent ID: 6844425
Filing Date: 2005-01-18
Classification: A61K,A61P

Abstract:
1. A compound comprising: (a) a biomolecule selected from somatostatin, neurotensin, bombesin-receptor binding molecules, antibodies, antennapedia peptide, and molecules binding to GPIIb/GPIIIa receptors; coupled to (b) an aromatic intercalating moiety with binding affinity for double-stranded DNA selected from acridine, porphyrin, ellipticine, phenantroline, carbazole, benzimidazole, and tetracycline compounds with cytostatic activity; which is complexed to (c) a γ-emitting radioactive metal selected from Tc-99m, Re-186, Re-188, and Mn, wherein said compound is associated with one or more pharmaceutically acceptable excipients.