Patent ID: 7507550
Filing Date: 2009-03-24
Classification: C07K,G01N,Y10S

Abstract:
1. An immunological test device for determining N-terminal pro-brain natriuretic peptide (NT-proBNP) comprising: a sample application zone for receiving a liquid sample; a monoclonal antibody directed against an epitope of NT-proBNP comprising amino acids 27 to 31, produced by hybridoma cell line 18.4.34 deposited with DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH under accession number DSM ACC2592, or a monoclonal antibody directed against an epitope of NT-proBNP comprising amino acids 13 to 16, produced by hybridoma cell line 17.3.1 deposited with DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH under accession number DSM ACC2591, a polyclonal antibody selected from polyclonal antibodies directed against epitopes of NT-proBNP comprising amino acids 39 to 50 or amino acids 38 to 42; and a detection zone in fluid communication with the sample application zone for binding a complex comprising NT-proBNP, the monoclonal antibody and the polyclonal antibody.