Patent ID: 7226794
Filing Date: 2007-06-05
Classification: G01N

Abstract:
1. A method for determining the presence of biomolecules using a surface-enhanced Raman spectroscopy (SERS) system, comprising: providing a first target biomolecule, a first target nanoparticle, and a first detector nanoparticle; forming a first detector complex electrochemically on a conductive substrate, wherein the first detector complex includes the first target biomolecule, the first target nanoparticle, and the first detector nanoparticle, wherein the first detector nanoparticle is disposed on the first target nanoparticle, wherein the first target nanoparticle is disposed on the first target biomolecule, and wherein the first target biomolecule is disposed on the conductive substrate; directing a laser at the first detector complex, wherein the interaction of the laser with the first detector complex produces a SERS signal specific for the first target biomolecule; and detecting the SERS signal, wherein the presence of the SERS signal indicates the presence of the biomolecule.