Patent ID: 9079901
Filing Date: 2015-07-14
Classification: A61P,C07D

Abstract:
1. A method of treating a disease in a human selected from the group consisting of diabetes, diabetic peripheral neuropathy, migraine, atrial arrhythmias, ventricular arrhythmias, heart failure, diastolic heart failure, systolic heart failure, acute heart failure, stable angina, unstable angina, exercise induced angina, congestive heart disease, ischemia, recurrent ischemia, reperfusion injury, myocardial infarction, acute coronary syndrome, peripheral arterial disease, pulmonary hypertension and intermittent claudication, comprising administering to a human in need thereof a therapeutically effective dose of a compound of Formula I: wherein: R R R R R R R R or a pharmaceutically acceptable salt, ester, or stereoisomer thereof, with the proviso that the compound is not 1-(3,4-difluorobenzyl)-2-oxo-N-(3-(3-oxo-2,3-dihydro-[1,2,4]triazolo[4,3-a]pyridin-6-yl)benzyl)-1,2-dihydropyridine-3-carboxamide.