Patent ID: 9125938
Filing Date: 2015-09-08
Classification: A61B,A61K,A61L,A61N,A61P,A61Q,C08B

Abstract:
1. A method of repairing a tissue or blood vessel defect, comprising: applying a 4-amino-1,8-naphthalimide compound to a tissue or blood vessel defect in need of repair; and activating the 4-amino-1,8-naphthalimide compound with a sufficient amount of an activating agent to repair the tissue or blood vessel defect; wherein the 4-amino-1,8-naphthalimide compound has a structure selected from the group consisting of: wherein R, R′, and Q are each independently selected from the group consisting of straight-chain and branched chain alkyl groups having from 2 to 200 carbons; and wherein X is selected from the group consisting of hydrogen, a halogen, a sulfonate ester, and a quaternary ammonium salt; and wherein the tissue or blood vessel defect is selected from the group consisting of a stretched artery, exposed subendothelium, puncture wounds, intimal wall flaps, and incised blood vessel.