Patent ID: 7638523
Filing Date: 2009-12-29
Classification: A61P,C07D

Abstract:
1. A method of treating a disease or condition in which c-kit receptor activity contributes to the pathology or symptomology of the disease or condition, the method comprising administering to a subject in need thereof a therapeutically effective amount of a compound having the structure of Formula (1) or Formula (46), or a pharmaceutically acceptable salt thereof, wherein the disease or condition is selected from asthma, allergic sinusitis, allergic rhinitis, atopic dermatitis, allergic contact dermatitis, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, psoriasis, pulmonary fibrosis, liver fibrosis, scleroderma, irritable bowel syndrome, idiopathic pulmonary arterial hypertension and primary pulmonary hypertension, and wherein: and wherein,