Patent ID: 6399700
Filing Date: 2002-06-04
Classification: A61K,C08G,C08J

Abstract:
A cell-regulating, polymeric composition comprising a blend of a cell-regulating, comb-type copolymer and one or more hydrophobic or non-cell regulating polymers, wherein the cell-regulating, comb-type copolymer comprises:a) a hydrophobic polymer backbone; b) non-cell hydrophilic polymeric side chains grafted to the polymer backbone, wherein the side chains have a molecular weight between 200 and 2000 Daltons; wherein between zero and 100% of the non-cell binding, hydrophilic side chains are end-capped with cell-binding or cell-signaling ligands to form short cell-binding copolymer side chains; and wherein the side chains comprise less than 60% of the total copolymer weight, and wherein the blend contains between 1 and 99% by weight of the comb-type copolymer.