Patent ID: 9044478
Filing Date: 2015-06-02
Classification: A61K,A61P,C07D

Abstract:
1. A method of treating neurodegenerative diseases in which a dysfunction of the Amyloid Protein Precursor (APP) metabolism occurs, comprising: administering at least a compound of formula (I) in which n and m are identical or different and independently represent an integer of greater than or equal to 2, the resulting hydrocarbon chain optionally comprising one or more heteroatoms selected from the group consisting of oxygen, nitrogen and sulphur, and, in which R 1 , R 2 , R 3 and R 4 , independently of each other, are selected from the group consisting of: a hydrogen atom, a (C an aryl group, an aralkyl group, where the aryl group is attached to a (C a heteroaryl group, where (R where each (C where the aryl group is selected from the group consisting of benzyl, phenyl, biphenyl, anthryl, phenylbenzyl, fluorenyl, naphthyl, dihydronaphthyl, tetrahydronaphthyl, indenyl and indanyl, where the heteroaryl group is selected from the group consisting of an aromatic monocycle, an aromatic bicycle, an aromatic tricycle and a bicycle or a tricycle of which one or two of the cycles is aromatic and the other cycle(s) is or are partially hydrogenated, from C where (R provided that at most two of the radicals chosen among R or their salts with pharmaceutically acceptable acids.