Patent ID: 9072663
Filing Date: 2015-07-07
Classification: A61K,A61P

Abstract:
1. A gastro-retentive agent delivery device for oral intake, the device configured for unfolding from a folded configuration for oral intake to an unfolded configuration for gastric retention, the device comprising: a first outer membrane and a second outer membrane sandwiching an internal layer therebetween; the first and second outer membranes being configured to provide sufficient mechanical force to unfold the device from the folded configuration to the unfolded configuration responsive to exposure to gastric medium, the internal layer being formulated to develop sufficient mechanical strength in the gastric medium to enable, upon unfolding of the device, the preservation of said unfolded configuration to provide gastric retention; the internal layer comprising a first active agent and at least one polymer substantially uniformly distributed throughout the internal layer, wherein in the folded configuration the device is sufficiently compact to be placed within a capsule.