Patent ID: 7414040
Filing Date: 2008-08-19
Classification: A61P,C07C,C07D,C07F

Abstract:
1. A compound represented by the following Formula (I): wherein: R, R and a substituent as represented by Formula (VII), where, p is 0-6, n is 0-2, W and Z are each independently selected from O, S and NR V and X are each independently selected from O, S and NR hydrogen, alkyl, cycloalkyl, C R R or R T is selected from O, S and NR P is selected from OR R R R m is 0-6; and Y is a cyclic or polycyclic, unsaturated or saturated, non-aromatic ring containing from 3 to 16 carbon atoms and optionally substituted with one or more substituents selected from the group consisting of: alkyl, substituted alkyl, aryl, substituted cycloalkyl, substituted aryl, aryloxy, oxo, hydroxy, alkoxy, cycloalkyl, acyloxy, amino, N-acylamino, nitro, cyano, halogen, —C(O)OR where n is 0-2, R R or R where R and pharmaceutically acceptable salts, and esters thereof; provided that at least one of R, R 1 , R 2 and R 3 is a substituted aryl group or a heterocyclic methylene substituent as represented in Formula (III) or a substituent as represented in Formula (VII).