Patent ID: 8055643
Filing Date: 2011-11-08
Classification: G06F,G06N,G06Q,G09B,G16B,G16H,H04L

Abstract:
1. A computer based method for determining a set of modifiable non-pangenetic attributes for altering a predisposition of an individual to a condition comprising: a) receiving a condition query describing the condition which identifies, within a computer memory, a set of query-attribute-positive attribute profiles associated with query-attribute-positive individuals having the condition and a set of query-attribute-negative attribute profiles associated with query-attribute-negative individuals not having the condition, wherein the query-attribute-positive attribute profiles and query-attribute-negative attribute profiles contain pangenetic and non-pangenetic attributes; b) accessing the pangenetic and non-pangenetic attributes of the individual; c) selecting a subset of query-attribute-positive attribute profiles from the set of query-attribute-positive attribute profiles wherein the subset of query-attribute-positive profiles has a statistically significant overlap with the pangenetic and non-pangenetic attributes of the individual, wherein the statistically significant overlap is determined with respect to a first threshold; d) selecting a subset of query-attribute-negative attribute profiles from the set of query-attribute-negative attribute profiles, wherein the subset of query-attribute negative profiles has statistically significant overlap with the pangenetic attributes of the individual, wherein the statistically significant overlap is determined with respect to a second threshold; e) determining a set of candidate attributes comprising non-pangenetic attributes from the query-attribute-positive attribute profiles that do not occur in statistically significant portion of the subset of query-attribute-negative attribute profiles, but which occur in a statistically significant portion of the subset of query-attribute-positive profiles, wherein the statistically significant portion is determined with respect to a third threshold; f) determining a set of modifiable non-pangenetic attributes derived from the set of candidate attributes, wherein removal of at least one those attributes from the query-attribute-positive profiles results in a statistically significant altered probability of the individual having the condition, wherein the statistically significant altered probability is determined with respect to a forth threshold; and g) transmitting the set of modifiable non-pangenetic attributes as a recommendation for predisposition modification in the individual.