Patent ID: 7524842
Filing Date: 2009-04-28
Classification: A61P,C07D

Abstract:
1. A compound represented by Formula (I): or a pharmaceutically acceptable salt, solvate, ester or isomer thereof, wherein: ring A is selected from the group consisting of aryl and heteroaryl, each of which is substituted with —Y—R X is selected from the group consisting of —S—, —O—, —S(O) T is alkynyl; V is selected from the group consisting H, alkyl, cycloalkyl, cycloalkenyl, aryl, heteroaryl, heterocyclyl, and N-oxides of said heteroaryl and heterocyclyl, wherein when each of said cycloalkyl, cycloalkenyl, aryl, heteroaryl, heterocyclyl, and N oxides of said heteroaryl and heterocyclyl contains two radicals on same or adjacent carbon atoms, said radicals may optionally be taken together with the carbon atom(s) to which they are attached to form a five- to eight-membered cycloalkyl, cycloalkenyl, aryl, heterocyclyl or heteroaryl ring, wherein each of the aforementioned cycloalkyl, cycloalkenyl, aryl, heteroaryl, and heterocyclyl, optionally with said five- to eight-membered cycloalkyl, cycloalkenyl, aryl, heterocyclyl, or heteroaryl is independently unsubstituted or substituted with one to four R Y is selected from the group consisting of a covalent bond, —(C(R Z is selected from the group consisting of a covalent bond, —(C(R m is 1 to 3; n is 1 to 3; R R each R each R R or wherein two R R or when two R R or when two R