Patent ID: 7531516
Filing Date: 2009-05-12
Classification: A61K,A61P,C07K

Abstract:
1. A peptide compound with affinity to human P-selectin of the sequence XA X A 3 A 1 A 2 A 1 Z, or a pharmaceutically acceptable acid or base addition salt thereof, wherein: each A A A A X marks the N-terminal side of said sequence and is a hydrogen or contains 1 to 6 D- or L-amino acid residues; and Z marks the C-terminal side of said sequence and is a hydroxyl or contains 1 to 11 D- or L-amino acid residues terminated by a hydroxyl, wherein X and Z together can form a cyclic system, provided that when the compound is cyclized by a Cys-Cys disulfide bond, each participating Cys residue is a member of X and Z respectively.