Patent ID: 6632651
Filing Date: 2003-10-14
Classification: A61F,A61K,A61L,C12M,C12N

Abstract:
A system for the maintenance of viable tissue comprising:(i) a chamber for holding the tissue, the chamber having in it an atmosphere, the composition of which is suitable for maintenance of viable biological tissue; (ii) means for maintaining the atmosphere at a substantially constant gas composition and for maintaining temperature at a substantially constant temperature; (iii) a reservoir for holding tissue culture medium, said reservoir being in flow communication with the chamber; (iv) a pump means for circulating the medium between the chamber and the reservoir in a controlled manner; and (v) control means for controlling the pump means to circulate the medium such that it produces rhythmic pulses of pressure on tissue in the chamber, said pressure being between 0.5 to 30 atm, and said rhythmic pulses having a frequency of 5-300 per minute.