Patent ID: 6462043
Filing Date: 2002-10-08
Classification: C07D

Abstract:
A compound of formulaQâ€”Aâ€”Qâ€ƒâ€ƒ(IIa), whereinA is a direct bond, C2-C12-alkylene, C2-C12-alkylene interrupted by one or two phenylene, cyclohexylene or piperazinylene radicals; cyclohexylene or phenylene; or the group â€”D1â€”D2â€”D3â€”, wherein D1 and D3 are phenylene or dicyclohexylene and D2 is 0 or C2-C4-alkylene; â€ƒwherein R1 is hydrogen or C1-C4-alkyl; R2 is hydrogen, C1-C6-alkyl, C3-C6-cycloalkyl; and Het is 2-chloropyrid-5-yl, tetrahydrofuran-3-yl, 5-methyl-tetrahydrofuran-3-yl or 2-chloro-thiazol-5-yl; and optionally the E/Z isomer, E/Z isomeric mixtures and/or tautomers thereof, each in free base form or in salt form.