Patent ID: 6303797
Filing Date: 2001-10-16
Classification: C07D

Abstract:
A compound represented by the formula [I] ##STR13##whereinY.sup.1 represents an oxygen atom, or a group represented by NH, O--CO, O--SO.sub.2, O--CO--NH, O--CS--NH, NH--CO, NH--SO.sub.2, NH--CO--NH or NH--CS--NH,R.sup.1 represents, each unsubstituted, a C.sub.1 -C.sub.16 alkyl group, a C.sub.2 -C.sub.10 alkenyl group, a C.sub.3 -C.sub.6 alkynyl group, a C.sub.6 -C.sub.12 aryl group, a C.sub.7 -C.sub.15 aralkyl group, a C.sub.9 -C.sub.15 arylalkenyl group, a C.sub.9 -C.sub.15 arylalkynyl group, a C.sub.3 -C.sub.6 cycloalkyl group, a C.sub.3 -C.sub.6 cycloalkyl C.sub.1 -C.sub.16 alkyl group, a C.sub.1 -C.sub.16 alkylcarbonyl group, a C.sub.1 -C.sub.16 alkoxycarbonyl group, a C.sub.6 -C.sub.12 arylcarbonyl group or a heterocyclic group; or a C.sub.1 -C.sub.16 alkyl group, a C.sub.2 -C.sub.10 alkenyl group, a C.sub.3 -C.sub.6 alkynyl group, a C.sub.6 -C.sub.12 aryl group, a C.sub.7 -C.sub.15 aralkyl group, a C.sub.9 -C.sub.15 arylalkenyl group, a C.sub.9 -C.sub.15 arylalkynyl group, a C.sub.3 -C.sub.6 cycloalkyl group, a C.sub.3 -C.sub.6 cycloalkyl C.sub.1 -C.sub.16 alkyl group, a C.sub.1 -C.sub.16 alkylcarbonyl group, a C.sub.1 -C.sub.16 alkoxycarbonyl group, a C.sub.6 -C.sub.12 arylcarbonyl group or a heterocyclic group, each having 1 to 5 substituents selected from the group consisting of a halogen atom, a cyano group, a hydroxy group, a C.sub.1 -C.sub.16 alkyl group (excluding the case where R.sup.1 is a C.sub.1 -C.sub.16 alkyl group), a C.sub.1 -C.sub.16 alkoxy group, a C.sub.1 -C.sub.16 alkylcarbonyloxy group, an amino group, a mono-C.sub.1 -C.sub.16 alkylamino group, a di-C.sub.1 -C.sub.16 alkylamino group, a carboxyl group, a C.sub.1 -C.sub.16 alkoxycarbonyl group, an aminocarbonyl group, a sulfo group, a C.sub.6 -C.sub.12 aryloxy group, a C.sub.7 -C.sub.15 aralkyloxy group and a heterocyclic group;with the proviso that when Y.sup.1 represents O--CO, R.sup.1 does not represent a 2,4-dimethylhexyl group, a 2-hydroxy-2,4-dimethylhexyl group, a 1,2-dihydroxy-2,4-dimethylhexyl group, a 1hydroxy-3,5-dimethylheptyl group, a 1,2-dihydroxy-5-methylheptyl group, a 1,2-dihydroxy-3,5-dimethylheptyl group or a 1hydroxy-1-phenylmethyl group, or a pharmacologically acceptable salt or ester thereof;in the above, the heterocyclic group being an aromatic heterocyclic group or a nonaromatic heterocyclic group, and meaning a 5- to 7-membered monocyclic heterocyclic group containing 1 to 4 hetero atoms selected from the group consisting of a nitrogen atom, an oxygen atom and a sulfur atom, or a condensed ring-type heterocyclic group wherein the above monocyclic heterocyclic group is condensed with the above-mentioned C.sub.3 -C.sub.6 cycloalkyl group, the above-mentioned C.sub.6 -C.sub.12 aryl group or another monocyclic heterocyclic group which is the same or different and defined as above.