Patent ID: 6306845
Filing Date: 2001-10-23
Classification: A61K,Y10S

Abstract:
A method for treating a demyelinating disease in a subject which comprises administering to the subject a therapeutically effective amount of a cardiac genin so as to treat the demyelinating disease, wherein the cardiac genin is a compound having the structure: ##STR9##whereinthe compound is (+) or (-);R.sub.1 is 2-pyrone or 2-furanone;R.sub.2 and R.sub.7 are each independently H, OH or OCOCH.sub.3 ;R.sub.3 is H;R.sub.4 is OH;R.sub.5 is H, or OH;R.sub.6 is H, or OH;R.sub.8, R.sub.9 and R.sub.11 are each independently H or OH;R.sub.10 is HCO.sub.3, CH.sub.3, CHO, or CH.sub.2 OH;R.sub.12 is H, OH or .dbd.O;or a pharmaceutically acceptable salt or ester thereof.