Patent ID: 8790591
Filing Date: 2014-07-29
Classification: G01N

Abstract:
1. An in vitro sensor for point-of-care (POC) detection of at least one analyte or reaction product, said sensor comprising: an inert, impermeable substrate including a first transparent surface oppositely disposed from a second surface and first and second cavities, each of said first and second cavities defining an opening at said second surface; a sensing system disposed in at least a portion of said first cavity, said sensing system comprising an analyte-detection optode membrane, an analyte-permeable membrane, and a plurality of non-transparent microbeads associated with at least one of said analyte-detection optode membrane and said analyte-permeable membrane, said analyte-permeable membrane being layered upon said analyte-detection optode membrane and covering said opening of said first cavity; and a reference system disposed in at least a portion of said second cavity.