Patent ID: 7638493
Filing Date: 2009-12-29
Classification: A61K,A61P

Abstract:
1. An artificial pulmonary surfactant composition comprising a lipid mixture composed of a phospholipid selected from the group consisting of dipalmitoyl-L-α-phosphatidylcholine (DPPC), egg yolk lecithin and soy lecithin, a higher alcohol selected from the group consisting of a saturated or unsaturated aliphatic, alcohol having from 14 to 20 carbon atoms or a saturated or unsaturated aliphatic, higher aliphatic amine having from 14 to 20 carbon atoms, and a higher aliphatic acid selected from the group consisting of a saturated or unsaturated aliphatic acid having from 14 to 20 carbon atoms, wherein said composition further comprises a peptide selected from the group consisting of: NH2-KLLKLLLKLWLKLLKLLL-COOH (SEQ. ID. NO: 1), NH2-KLLKLLLKLWKKLLKLLK-COOH (SEQ. ID. NO: 2) and NH2-KKLKKLLKKWKKLLKKLK-OH (SEQ. ID. NO: 3).