Patent ID: 6440971
Filing Date: 2002-08-27
Classification: A61P,C07F,H01L

Abstract:
A binuclear DNA-threading transition metal complex with the general formula(L1)-M1-(D1-B-D2)-M2-(L2) wherein:D1-B-D2 is a bridging ligand; D1 and/or D2 are a substituent having an optionally substituted cyclopentadipyrido[b:3,2-h: 2â€²,3â€²-j]phenazine-12-carboxylic acid; B, covalently linking the ring system D1 to D2, is any appropriately substituted chain of at least two atoms; M1 is a transition metal ion with octahedral co-ordination sphere that is capable of forming substitution-inert co-ordination bonds to the D1 moiety of the bridging ligand as well as to at least one of the bi- or polydentate ligands of set L1; M2 is any transition metal ion; and L1 and/or L2 are a substituent having pyridyl groups, said pyridyl groups selected from the group consisting of 2,2â€²-bipyridine, 4,4â€²-dimethyl-2,2â€²-bipyridine and 2,2â€²,6â€²2â€³-terpyridine.