Patent ID: 6245350
Filing Date: 2001-06-12
Classification: A61J,A61K

Abstract:
A process for the encapsulation of caplets in a capsule, comprising the following steps:a. providing empty first and second capsule shell parts,b. filling at least one of said capsule parts with one or more caplets, wherein the clearance between the capsule part and the caplet is in the range of from -0.5-0.5 mm.,c. putting said capsule parts together,d. treating the combined capsule parts by cold shrinking,wherein the empty capsule parts are either kept after production at humid conditions in the range of from about 40 to about 90% relative humidity to retain a moisture content in the range of from about 14 to about 19% by weight of the capsule shell or are re-humidified to said moisture content before feeding into a capsule filling machine and wherein the first capsule part is kept under humid conditions within the filling machine at said moisture content during rectifying and assembling with a caplet having a moisture content in the range of from about 0 to about 12% by weight the second capsule part is processed in the same manner, and the encapsulated dosage form is dried at a relative humidity in the range of from about 20 to about 40% and a temperature in the range of from about 15 to about 60 C.