Patent ID: 7901689
Filing Date: 2011-03-08
Classification: A61K,A61P,C07K,C12N,Y02A

Abstract:
1. A chimeric peptide represented by formula (I) or formula (II), or chimeric peptides which are mixtures of formula (I) peptides, mixtures of formula (II) peptides, or mixtures of formula (I) and formula (II) peptides, wherein: N is the first 2, 3, 4, or 5 amino acid residues from the free N-terminus of a naturally-occurring amyloid β peptide that is formed by proteolytic cleavage of β amyloid precursor protein (βAPP); C is the last 2, 3, 4, or 5 amino acid residues from the free C-terminus of a naturally-occurring amyloid β peptide that is formed by proteolytic cleavage of β amyloid precursor protein (βAPP); T S is a spacer amino acid residue; m is 0, 1, 2, 3, 4, or 5; and n is 1, 2, 3, or 4.