Patent ID: 7696364
Filing Date: 2010-04-13
Classification: A61P,C07D,Y02P

Abstract:
1. An alkenylation process comprising carrying out an alkenylation, in the presence of an indium (III) salt catalyst, of an aromatic compound containing at least one hydroxy group with a compound of formula III and/or a compound of formula IV in an organic solvent wherein the aromatic compound containing at least one hydroxy group has at least one unsubstituted position, as well as 0-to-4 linear C R n is an integer of from 0-to-3, and the organic solvent is an aprotic non-polar organic solvent, an aprotic polar solvent or a two-phase solvent system comprising one or more aprotic non-polar organic solvents and one or more aprotic polar solvents, where the aprotic non-polar organic solvent(s) is/are selected from the group consisting of aliphatic hydrocarbons, aromatic hydrocarbons, halogenated aliphatic hydrocarbons, halogenated aromatic hydrocarbons, and mixtures of two or more thereof, and the aprotic polar solvent(s) is/are selected from the group consisting of aliphatic carbonates, cyclic carbonates, aliphatic esters, cyclic esters, aliphatic ketones, cyclic ketones and mixtures of two or more thereof.