Patent ID: 8933230
Filing Date: 2015-01-13
Classification: A61K,A61P,C07F

Abstract:
1. A compound comprising a phosphorus-containing group-substituted quinoline, wherein the compound is represented by formula (I) below: in formula (I), Z represents V 1 and V 2 are each independently selected from hydrogen, halogen, —OCF 3 , —CF 3 , —NO 2 , —CN, —OH, —NH 2 , —NMe 2 , C 1-6 alkyl, C 3-6 cycloalkyl, C 3-6 heterocycloalkyl, C 1-6 alkoxy, C 3-6 cycloalkoxy, or C 3-6 heterocycloalkoxy; either of R and R′ represents phosphorus-containing substituent Q, the other is selected from hydrogen, methoxyl, methoxyethoxyl, or phosphorus-containing substituent Q; wherein, the phosphorus-containing substituent Q represents, A is absent or represents O, NH, S(═O) L is absent or represents C J is absent or represents O, NH, S(═O) X is absent or represents —C(═O)—, —S(O) Y is absent or represents C R R wherein, G R m=0-2; or a racemate or enantiomer thereof.