Patent ID: 6352555
Filing Date: 2002-03-05
Classification: A61F,A61K,A61L,A61P,C12N,Y10S

Abstract:
A method for implanting cells onto a prosthesis comprising the steps of:(a) providing a prosthesis comprising a porous tube, wherein at least 25% of the pores on the inner surface of said tube have diameters of more than about 40 &mgr;m and at least 25% of the pores on the outer surface of said tube have diameters of less than about 30 &mgr;m, wherein said tube comprises a substantially continuous layer of a biocompatible material, and wherein said pores on said inner surface and said pores on said outer surface are connected by gradually tapered openings; (b) contacting said prosthesis with a suspension of cells; and (c) providing a pressure differential between said inner surface and said outer surface, whereby said cells are retained in said pores of said inner surface.