Patent ID: 8901104
Filing Date: 2014-12-02
Classification: A61K,A61L,A61P

Abstract:
1. A method of inhibiting Instant Blood-Mediated Inflammatory Reaction (IBMIR) in a patient, comprising administering a therapeutically effective amount of dextran sulfate, or a pharmaceutically acceptable salt thereof, to a patient in need of such treatment, wherein said dextran sulfate, or said pharmaceutically acceptable salt thereof, has an average molecular weight of less than 20,000 Da and an average sulphur content in a range of 10 to 25%, and wherein inhibiting IBMIR comprises administering said therapeutically effective amount of said dextran sulfate, or said pharmaceutically acceptable salt thereof, resulting in a concentration of said dextran sulfate, or said pharmaceutically acceptable salt thereof, in the blood of said patient of less than 5 mg/ml.