Patent ID: 6643544
Filing Date: 2003-11-04
Classification: A61N

Abstract:
An iontophoresis device which transdermally or transmucosally administers a prostaglandin, comprising:(a) a first electrode structure containing a prostaglandin; (b) a second electrode structure containing a prostaglandin; and (c) a power supply electrically connected between the first and second electrode structures and equipped with constant-current supplying means and polarity inverting means, wherein the first and the second electrode structures include stabilizing means for inhibiting hydrolysis of the prostaglandin during storage, the stabilizing means being a drug retainer which retains a prostaglandin in a dry condition, and wherein a stabilizing agent for chemically stabilizing a prostaglandin or a dissolution promoter is added to the stabilizing means, and wherein the power supply conducts energization with a polarity inverting period of 1 minute to 2 hours.