Patent ID: 7906283
Filing Date: 2011-03-15
Classification: C12Q

Abstract:
1. A method of screening human patients to identify those patients more likely to exhibit an increased risk of treatment-emergent suicidal ideation after treatment with a selective serotonin reuptake inhibitor (SSRI) and detecting the presence of a genotype in the patients which is associated with an increased risk of treatment-emergent suicidal ideation (TESI) after treatment with a SSRI comprising: (a) obtaining a sample of genetic material from the patients, (b) assaying the sample for the presence of a genotype in the patients which is associated with an increased risk of treatment-emergent suicidal ideation after treatment with a SSRI by performing an assay suitable for detection of a polymorphism, and (c) identifying those patients more likely to exhibit an increased risk of treatment-emergent suicidal ideation after treatment with a SSRI based on the presence of the genotype associated with an increased risk of treatment-emergent suicidal ideation in (b),