Patent ID: 7067650
Filing Date: 2006-06-27
Classification: C12N

Abstract:
1. A set of ribozymes which comprises at least one ribozyme capable of binding and cleaving Bradeion α mRNA which corresponds to DNA comprising a nucleotide sequence shown in SEQ ID NO:1, and at least one ribozyme capable of binding to and cleaving Bradeion β mRNA which corresponds to DNA comprising a nucleotide sequence shown in SEQ ID NO:3, wherein said ribozyme capable of binding to and cleaving Bradeion α mRNA targets a sequence selected from the group consisting of RNA sequences corresponding to nucleotide numbers 569-583, 588-602, 595609 and 699-713 of SEQ ID NO:1, and said ribozyme capable of binding and cleaving Bradeion β mRNA targets a sequence selected from the group consisting of RNA sequences corresponding to nucleotide numbers 108-122, 157-171, 304-318 and 378-392 of SEQ ID NO:3.