Patent ID: 7807713
Filing Date: 2010-10-05
Classification: A61P,C07C

Abstract:
1. A method for the treatment of a mammal suffering from an androgen-dependent disorder comprising administering to the mammal in need thereof a therapeutically effective amount of a compound of formula (I) wherein R 1 is hydrogen, fluorine, chlorine, bromine, cyano, hydroxy, methyl acrylate, or C 1 -C 6 alkyl optionally substituted with hydroxy; R R a compound of formula (II) wherein R 4 is plenyl optionally substituted with hydroxy; C 1 -C 6 phenylalkyl; or benzyl optionally substituted with hydroxy, C 1 -C 6 alkoxy optionally substituted with methoxy or cyano, C 1 -C 6 alkyl, C 1 -C 5 alkanoate, or C 1 -C 5 alkylamine; or a combination thereof wherein the androgen-dependent disorder I selected from the group consisting of prostate cancer, acne, seborrhea, hirsutism, alopecia and hidradenitis suppurativa.