Patent ID: 7605176
Filing Date: 2009-10-20
Classification: C07C,C07D

Abstract:
1. A compound of formula I wherein: R R X is a C Z is a single bond or —CR Y denotes indolyl, which may be mono- or polysubstituted at one or more C atoms by R A denotes phenyl, which may be mono- or polysubstituted by R B denotes phenyl, which may be mono- or polysubstituted by R b has the value 0 or 1, Cy is a saturated 3- to 7-membered carbocyclic group, an unsaturated 4- to 7-membered carbocyclic group, a phenyl group, a saturated 4- to 7-membered or unsaturated 5- to 7-membered heterocyclic group with an N, O, or S atom as heteroatom, a saturated or unsaturated 5- to 7-membered heterocyclic group with two or more N atoms or with one or two N atoms and one O or S atom as heteroatoms, an aromatic heterocyclic 5- or 6-membered group with one or more identical or different heteroatoms selected from N, O, and/or S, wherein the 4-, 5-, 6-, or 7-membered groups of Cy are optionally fused to a phenyl or pyridine ring via two common adjacent C atoms, and in the 5-, 6-, or 7-membered groups of Cy one or two non-adjacent —CH R R R R wherein if R 7a and R 7b are each alkyl, they are optionally joined together such that a C 3-7 -cycloalkyl group is formed together with the C atom to which R 7a and R 7b are linked, and/or if R 7c and R 7d are each alkyl, they are optionally joined together such that a C 3-7 -cycloalkyl group is formed together with the C atom to which R 7c and R 7d are linked, or R 7b and R 7d are each alkyl, they are optionally joined together such that a C 3-7 -cycloalkyl group is formed together with the two C atoms to which R 7b and R 7d are linked; R R R R R R R R R R R wherein in each of the abovementioned groups and radicals one or more C atoms are optionally additionally mono- or polysubstituted by F and/or in each case one or two C atoms are optionally independently additionally monosubstituted by Cl or Br and/or one or more phenyl rings optionally independently additionally comprise one, two, or three substituents selected from the group F, Cl, Br, I, C 1-4 -alkyl, C 1-4 -alkoxy, difluoromethyl, trifluoromethyl, hydroxy, amino, C 1-3 -alkylamino, di-(C 1-3 -alkyl)-amino, acetylamino, aminocarbonyl, cyano, difluoromethoxy, trifluoromethoxy, amino-C 1-3 -alkyl, C 1-3 -alkylamino-C 1-3 -alkyl, and di-(C 1-3 -alkyl)-amino-C 1-3 -alkyl and/or are optionally monosubstituted by nitro, and the H atom of a carboxy group or an H atom bound to an N atom are each optionally replaced by a group which can be cleaved in vivo, or a tautomer, enantiomer, salt, or mixture thereof.