Patent ID: 6758961
Filing Date: 2004-07-06
Classification: G01N

Abstract:
A method for analyzing membranous samples, comprising:selecting a measuring arrangement, comprising: (i) a carrier having at least one aperture, (ii) at least two fluid compartments, separated by the carrier, each fluid compartment connected to at least one of the other fluid compartments via at least one of the apertures, and (iii) at least two electrodes, each electrode being in electrical contact with at least one of the fluid compartments; introducing a sample into one of the fluid compartments; applying a voltage between at least two of the electrodes to generate an electric field in the compartment containing the sample; moving the sample onto the aperture, under the influence of the electric field; sealing the sample across the aperture; adding a pore former to at least one fluid compartment to increase the electrical conductivity or permeability of at least a portion of the sample toward certain ions; and measuring at least one of an electrical potential and a current across at least a portion of the sample, after the sample is moved to and sealed across the aperture.