Patent ID: 8088931
Filing Date: 2012-01-03
Classification: A61P,C07D

Abstract:
1. A method of preparing a compound of Formula X, comprising: a) condensing a compound of Formula 1 with a compound of Formula 2, to form a compound of Formula 3; b) condensing the compound of Formula 3 with a compound of Formula 4 and a compound of Formula 5 to form a compound, and reacting that compound with an amine having Formula HNR c) treating the compound of Formula 6 with an oxidizing agent to form a compound of Formula X; wherein: R R R R R n, m, and p are each independently 1-6; and each R′, R″ and R′″ is independently H or optionally substituted alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, aryl, or heterocyclic; or R′ and R″, or R″ and R′″, form a ring.