Patent ID: 6335344
Filing Date: 2002-01-01
Classification: C07D

Abstract:
A compound of the formula or a pharmaceutically acceptable salt thereof, wherein:n is 0 to 2; R1 is hydrogen or C1-C8 alkyl optionally substituted by 1 to 3 substituents independently selected from the group consisting of halo, C1-C4 alkoxy, â€”NR6R7, and â€”SO2R5; each R2 is independently selected from the group consisting of halo, hydroxy, C1-C6 alkyl, â€”NR6R7, and C1-C4 alkoxy, wherein said alkyl group and the alkyl moieties of said R2 groups are optionally substituted by 1 to 3 substituents independently selected from the group consisting of halo, C1-C4 alkoxy â€”NR6R7 and â€”SO2R5; R3 is -(ethynyl)-R8, wherein R8 is hydrogen or C1-C6 alkyl optionally substituted by hydroxy, â€”OR6, or â€”NR6R7; each R5 is C1-C4 alkyl optionally substituted by 1 to 3 halogens; and R6 and R7 are independently selected from hydrogen and R5.