Patent ID: 6300333
Filing Date: 2001-10-09
Classification: A01N,C07D

Abstract:
A compound of the formula (I) ##STR20##in whichR.sup.1 is hydrogen, halogen, (C.sub.1 -C.sub.8)-alkyl, (C.sub.1 -C.sub.8)-haloalkyl, (C.sub.1 -C.sub.8)-alkoxy or (C.sub.3 -C.sub.6)-cycloalkyl;R.sup.2 and R.sup.3 are identical or different and in each case are hydrogen, (C.sub.1 -C.sub.8)-alkyl, (C.sub.2 -C.sub.8)-alkenyl, (C.sub.2 -C.sub.8)-alkynyl, (C.sub.1 -C.sub.8)-alkoxy, halogen, hydroxyl, cyano, nitro, thiocyano, (C.sub.1 -C.sub.8)-alkanoyl, (C.sub.1 -C.sub.8)-alkoxycarbonyl, (C.sub.1 -C.sub.8)-alkylthio, (C.sub.1 -C.sub.8)-alkysulfinyl, (C.sub.1 -C.sub.8)-alkylsulfonyl, amino, (C.sub.1 -C.sub.8)-alkylamino, (C.sub.1 -C.sub.8)-dialkylamino or (C.sub.3 -C.sub.6)-cycloalkyl, it being possible for a saturated carbon unit in the alkyl, cycloalkyl, alkenyl and alkynyl radicals or the groups derived from these to be replaced by a hetero atom unit or dimethylsilyl, and it furthermore being possible for up to three hydrogen atoms in these radicals or in the groups derived from these to be replaced by halogen, in the case of fluorine it also being possible for all hydrogen atoms to be replaced by fluorine; orR.sup.2 and R.sup.3 together with the carbon atoms to which they are bonded form an unsaturated 5- or 6-membered isocyclic ring which, if it is a 5-membered ring, optionally contains an oxygen or sulfur atom in place of CH.sub.2 or which, if it is a 6membered ring, optionally contains one or two nitrogen atoms in place of one or two CH units and which is optionally substituted by 1, 2 or 3 identical or different radicals and these radicals are ((C.sub.1 -C.sub.4)-alkyl, (C.sub.1 -C.sub.4)-haloalkyl, halogen,(C.sub.1 -C.sub.4)-alkoxy or (C.sub.1 -C.sub.4)-haloalkoyl; or R.sup.2 and R.sup.3 together with the carbon atoms to which they are bonded form a saturated 5-, 6- or 7-membered isocyclic ring which optionally contains oxygen and/or sulfur in place of one or two CH.sub.2 groups and which is optionally substituted by 1, 2 or 3 (C.sub.1 -C.sub.4)-alkyl groups;A is N;X is NH, oxygen or S(O).sub.q where q=0, 1 or 2;Y is oxygen, sulfur or a group NR.sup.5' or NR.sup.5"" where R.sup.5' and R.sup.5"" are identical or different and in each case have the meanings given hereinbelow for R.sup.5, or, in the event that Y is a group NR.sup.5', R.sup.5"" is additionally nitro, cyano, hydroxyl, alkoxy or a group NR.sup.5'"" R.sup.5'"" where R.sup.5'"" and R.sup.5'"" are identical or different and in each case may have the meanings given hereinbelow for R.sup.5,Z is oxygenm and n are both the number 2;R.sup.4 and R.sup.4' are hydrogen;R.sup.5 is alkyl, alkenyl, alkynyl, aryl, heterocyclyl, it being possible for the aryl or heterocyclyl radicals mentioned to be unsubstituted or to have attached to them up to three, in the case of fluorine also up to the maximum number of, identical or different radicals, and it being possible, in the alkyl, alkenyl or alkynyl radicals mentioned, for one or more non-adjacent saturated carbon units to be replaced by a carbonyl group or by hetero atom units;and in which, in addition, 3 to 12 atoms of these hydrocarbon radicals which are optionally modified as above optionally form a cycle;and it being possible for these hydrocarbon radicals, with or without the abovementioned variations, optionally to be substituted by one or more in the case of fluorine up to the maximum number of, identical or different radicals selected from the group consisting of halogen, aryl, aryloxy, arylthio, cycloalkyl, cycloalkoxy, cycloalkylthio, heterocyclyl, heterocyclyloxy, heterocyclthio, alkanoyl, cycloalkanoyl, haloalkanoyl, aroyl, arylalkanoyl, cycloalkylalkanoyl, heterocyclylalkanoyl, alkoxycarbonyl, haloalkoxycarbonyl, cycloalkoxycarbonyl, cycloalkylalkoxycarbonyl, arylalkoxycarbonyl, heterocyclylalkoxycarbonyl, aryloxycarbonyl, heterocyclyoxycarbonyl, alkanoyloxy, halogenalkanoyloxy, cycloalkanoyloxy, cycloalkylalkanoyloxy, aroyloxy, arylalkanoyloxy, heterocycloylalkanoyloxy, alkylsulfonyloxy, arylsulfonyloxy, hydroxyl, cyano, thiocyano or nitro, it being possible for the cycloaliphatic, aromatic or heterocyclic ring systems amongst the substituents which have just been mentioned to be unsubstituted or to have attached to them up to three, in the case of fluorine also up to the maximum number of identical or different substituents,and it furthermore being possible, in the event that Y is a group NR.sup.5', R.sup.5' of group Y and R.sup.5 of group Z to be linked to form a 5-8-membered heteroaliphatic ring system;or a tautomer or salt thereof.