Patent ID: 7855207
Filing Date: 2010-12-21
Classification: A61P,C07D

Abstract:
1. A compound of formula (I), the N-oxide forms, the pharmaceutically acceptable salts and the stereo-chemically isomeric forms thereof, wherein n is 0, 1 or 2; X is N or CR R R R wherein s is 0, 1, 2 or 3; R R or R 3 is a group of formula wherein t is 0, 1, 2 or 3; —Z is a heterocyclic ring system selected from wherein R C R R when R 5 and R 6 are on adjacent positions they may taken together form a bivalent radical of formula wherein R and aryl is phenyl, phenyl substituted with halo, C 1-6 alkyl or C 1-6 alkyloxy.