Patent ID: 7037938
Filing Date: 2006-05-02
Classification: A61P,C07C,C07D,Y02P

Abstract:
1. A compound selected from the group consisting of (1) 4′-[(2R)-2-[[(2R)-2-Phenyl-2-hydroxyethyl]amino]propyl]-3-methoxy-1,1′-biphenyl-4-carboxylic acid, (2) 4′-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-3-isopropyloxy-1,1′-biphenyl-4-carboxylic acid, (3) 4′-[2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]-amino]ethyl]-3-methoxy-1,1′-biphenyl-4-carboxylic acid, (4) 4′-[2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]ethyl]-2,3-dimethyl-1,1′-biphenyl-4-carboxylic acid, (5) 4′-[2-[[(2R)-2-(3-Fluorophenyl)-2-hydroxyethyl]amino]ethyl]-3-propoxy-1,1′-biphenyl-4-carboxylic acid, (6) 4′-[(2R)-2-[[(2R)-2-(3-Fluorophenyl)-2-hydroxyethyl]amino]propyl]-3-propoxy-1,1′-biphenyl-4-carboxylic acid, (7) 4′-[2-[[(1S,2R)-2-Hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-3-isopropoxy-1,1′-biphenyl-4-carboxylic acid, and (8) 4′-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethyl]-3-isobutyl-1,1′-biphenyl-4-carboxylic acid, or a pharmaceutically acceptable salt thereof.