Patent ID: 6147105
Filing Date: 2000-11-14
Classification: C07D

Abstract:
A 2-Phenylindole of formula I ##STR5## n which R.sup.1 is --(CH.sub.2).sub.n --S(O).sub.m --R.sup.4, --(CH.sub.2).sub.n --NR.sup.6 --SO.sub.2 --R.sup.4, or ##STR6## wherein n and n' are integers from 4 to 12 and m and m' are 0, 1 or 2, and X stands for a methylene group, an imino group .dbd.NR.sup.6, or an oxygen or sulfur atom,R.sup.2 and R.sup.3, independently of one another, mean a hydrogen atom, a C.sub.1 to C.sub.10 alkyl group, a benzyl, alkanoyl or alkanoyloxy or carbarnoyl radical of formula --C(O)R.sup.5 or --C(O)NR.sup.6 R.sup.7 or a tetrahydropyranyl group,R.sup.4 means a hydrogen atom, a C.sub.1 to C.sub.10 alkyl group, a completely or partially fluorinated alkyl group --(CH.sub.2).sub.o --(CF.sub.2).sub.p CF.sub.3, whereby o and p, independently of one another, are in each case an integer from 0 to 6, an (alkyl)amino or (alkyl)carbamoyl group of formula --(CH.sub.2).sub.q --Y--NR.sup.8 R.sup.9, whereby q is an integer from 0 to 6 and Y stands for a direct bond, a methylene or carbonyl group, or phenyl, naphthyl, benzyl, phenylethyl, naphthylmethyl, pyridinyl, imidazolyl optionally substituted by C1-4-alkyl, pyrazinyl, pyrimidinyl, or thienyl, but if Y means a carbonyl group and m is 2, q cannot be 0,R.sup.5 means a C.sub.1 to C.sub.10 alkyl or C.sub.1 to C.sub.10 alkyloxy group, or a phenyl or benzyl radical,R.sup.6, R.sup.7, R.sup.8 and R.sup.9, independently of one another, mean a hydrogen atom, or a C.sub.1 to C.sub.10 alkyl or benzyl group, andR.sup.10 and R.sup.11 together mean a di-, tri- or tetramethylene bridge, which also can have a C--C double bond anywhere in the bridge.