Patent ID: 6268358
Filing Date: 2001-07-31
Classification: A61K,C07D

Abstract:
A method for treating patients suffering from Alzheimer's disease or a related dementia characterized by a cholinergic deficiency or dementias accompanied by plaques and tangles in the brain which comprises administering to a patient suffering from such a disease a therapeutically effective amount of a compound other than galanthamine of the formula: ##STR55##wherein R.sub.1 and R.sub.2 are each independently selected from the group consisting of hydrogen, hydroxyl alkoxy of 1-6 carbon atoms, aryloxy, alkyl carbamate, aryl carbamate and alkanoyloxy groups, wherein said aryl groups may optionally be substituted by an R.sup.5 group selected from the group consisting of alkyl, alkoxy, fluoro, chloro, bromo and trifluoromethyl groups and R.sub.3 is selected from the group consisting of hydrogen and straight or branched chain alkyl groups of from one to six carbon atoms and alkyl phenyl groups.