Patent ID: 6727263
Filing Date: 2004-04-27
Classification: A61P,C07D

Abstract:
An indole or 2,3-dihydro-indole derivative of the formula: any of its enantiomers or any mixture thereof, or an acid addition salt thereof, whereinX is â€”Oâ€” or â€”Sâ€”, or â€”CR4R5â€”; and Y is â€”CR6R7â€”,â€”CR6R7â€”CR8R9â€”, or â€”CR6&boxH;CR7â€”; or X and Y together form a group â€”CR4&boxH;CR5â€”, or â€”CR4&boxH;CR5â€”CR6R7â€”; Z is â€”Oâ€” or â€”Sâ€”; A is selected from a group of formula (II) and (IV) wherein the dotted lines mean an optional bond; R1, R2, R3, R12, R13, R14, R15, R16 and R17 are each independently selected from hydrogen, halogen, trifluoromethyl, alkyl, alkenyl, alkynyl, cycloalkyl, alkoxy, hydroxy, formyl, acyl, amino, alkylamino, dialkylamino, acylamino, alkoxycarbonylamino, aminocarbonylamino, alkylaminocarbonylamino, dialkylaminocarbonylamino, nitro and cyano; R4, R5, R6, R7, R8 and R9 are each independently selected from hydrogen and alkyl; and R11 is selected from hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, phenyl, naphthyl, phenylalkyl, acyl and formyl.