Patent ID: 6166200
Filing Date: 2000-12-26
Classification: A61K,C07C,C07D,C07K

Abstract:
A compound of general formula I'A ##STR24## wherein R.sup.1', independently of one another, stand for a hydrogen atom, a metal ion equivalent of atomic numbers 20-29, 39, 42-44 or 57-83 or an acid protective group,R.sup.2 stands for a hydrogen atom, or a methyl or an ethyl radical, which optionally is substituted with 1-2 hydroxy or 1 carboxy group(s),R.sup.3' stands for a ##STR25## R.sup.4 stands for a straight-chain, branched, saturated or unsaturated C.sub.1 -C.sub.30 alkyl chain, which optionally is interrupted by 1-10 oxygen atoms, 1 phenylene group, or 1 phenylenoxy group and/or optionally is substituted by 1-5 hydroxy, 1-3 carboxy, or 1-phenyl group(s),U.sup.6 stands for a straight chain, branched, saturated or unsaturated C.sub.1 -C.sub.20 alkylene group optionally containing 1-5 imino, 1-3 phenylene, 1-3 phenylenoxy, 1-3 phenylenimino, 1-5 amide, 1-2 hydrazide, 1-5 carbonyl, 1-5 ethylenoxy, 1 urea, 1 thiourea, 1-2 carboxyalkylimino, 1-2 ester groups and/or 1-10 oxygen, 1-5 sulfur and/or 1-5 nitrogen atom(s) and/or optionally substituted by 1-5 hydroxy, 1-2 mercapto, 1-5 oxo, 1-5 thioxo, 1-3 carboxy, 1-5 carboxyalkyl, 1-5 ester and/or 1-3 amino group(s), wherein the phenylene groups that are optionally contained can be substituted by 1-2 carboxy, 1-2 sulfo or 1-2 hydroxy groups,T' stands for a --C*O, --COOH, --N.dbd.C.dbd.O or --N.dbd.C.dbd.S group, andC*O stands for an activated carboxyl group.