Patent ID: 6696477
Filing Date: 2004-02-24
Classification: B60G,B64C,C07D

Abstract:
A compound of Formula I wherein A is pyrazolyl optionally substituted, it possible, with a radical selected from acyl, halo, alkyl, haloalkyl, cyano, nitro, carboxyl, alkoxy, aminocarbonyl, alkoxycarbonyl, carboxyalkyl, cyanoalkyl, and hydroxyalkyl; wherein y is one or more radicals selected from alkynyl, alkenyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl, heterocyclo and heterocycloalkyl; wherein R1 is a substituent selected from cycloalkyl, cycloalkenyl and aryl, wherein R1 is optionally substituted at a substitutable position with one or more radicals selected from alkyl, haloalkyl, cyano, carboxyl, alkoxycarbonyl, hydroxyl, hydroxyalkyl, haloalkoxy, amino, alkylamino, arylamino, nitro, alkoxyalkyl, alkylsulfinyl, halo, alkoxy and alkylthio; wherein R2 is amino; wherein R3 is a radical selected from wherein R4 is a radical selected from hydrido, hydroxyl, alkyl, aryl, heterocyclo and cycloalkyl; wherein R5 is a radical selected from hydrido, alkyl, aryl, heterocyclo and cycloalkyl; and wherein R6 is a radical selected from hydrido and hydroxyl; or a pharmaceutically-acceptable salt thereof; wherein said cycloalkyl is monocyclic or bicyclic, and contains 3-12 ring carbons, and wherein said heterocyclo is monocyclic or bicyclic, and contains 3-12 ring atoms selected from the group consisting of carbon, nitrogen, sulfur, and oxygen.