Patent ID: 8163693
Filing Date: 2012-04-24
Classification: A61K,A61P,C07K

Abstract:
1. A compound of the formula: or a pharmaceutically acceptable salt thereof, where m is 1 or 2; n is 0, 1, or 2; t is 0, 1, or 2; wherein the group contains 0, 1, or 2 double bonds; R is hydrogen, C R, when t is 1, is optionally joined with T to form a 5- to 7-membered heterocycloalkyl ring containing 0, 1, or 2 additional heteroatoms or heteroatom groups independently chosen from N, O, S, SO, and SO R R R R R R R R R where p is 1 or 2; R R U is a single bond, CH T is hydrogen, R T, when t is 1, is optionally joined with R to form a 5- to 7-membered heterocycloalkyl ring; or T, when t is 0, is optionally joined with R T is a group of the formula: A is hydrogen, R A is joined with B to form a 5- to 7-membered heterocycloalkyl ring containing 0, 1, or 2 additional heteroatoms or heteroatom groups independently chosen from N, O, S, SO, and SO B is hydrogen or C B is joined in a heterocycloalkyl ring with A; J is CR L is CR M is hydrogen, halogen, hydroxy, C Only one of J, L, and M is taken together with Y to form a ring; Y is absent, CR Y is taken together with one of J, L, or M to form a ring; Z, when present, is C R R R R R R R R R