Patent ID: 9156811
Filing Date: 2015-10-13
Classification: A61K,A61P,C07D

Abstract:
1. A method of treating an N-myristoyl transferase (NMT) related disease or disorder in a subject, wherein the disease or disorder is cancer selected from the group consisting of cancers of the lung, breast, esophagus, blood, glioma, bladder, fibrosarcoma and colon, or a parasitic infection resulting from T. brucei brucei , the method comprising administering to said subject a therapeutically effective amount of a compound of formula (IV)(ii) or a pharmaceutically acceptable salt or pro-drug thereof: wherein n is 0; W and X, one of which may be absent, are independently selected from a hydrocarbyl group optionally substituted with R a —(CH R R q is 0, 1, 2, 3 or 4, wherein the values of R