Patent ID: 7767665
Filing Date: 2010-08-03
Classification: A61K,A61P,C07D

Abstract:
1. A compound represented by the formula: wherein R wherein: said substituent(s) which may be attached to the alkoxy are the same as the substituent(s) for the hydrocarbon group which may have a substituent(s) represented by R said acyl is represented by the formula: —(C═O)—R said substituent(s) for the hydrocarbon group which may have a substituent(s) represented by R said substituent(s) for the 5- to 7-membered saturated cyclic amino which may have a substituent(s) being C said substituent(s) for the heterocyclic group which may have a substituent(s) represented by R said substituent(s) for the amino optionally having a substituent(s) represented by R R (1) halogen atom, (2) C (3) C (4) C (5) C (6) C (7) C (8) C (9) C (10) C (11) C (12) C (13) C (14) carboxy, (15) C (16) C (17) C (18) C (19) amino which may have a substituent(s), (20) 5- to 7-membered (preferably 5- or 6-membered) saturated cyclic amino which may have a substituent(s), (21) carbamoyl which may have a substituent(s), (22) (5- to 7-membered cyclic amino)-carbonyl which may have a substituent(s), (23) 5- to 10-membered aromatic heterocyclic group which may have a substituent(s), (24) (5- to 10-membered aromatic heterocyclic group)-thio which may have a substituent(s), (25) C (26) oxo, or (27) cyano, wherein the substituent(s) of the above described (2)-(13) and (15)-(25) are (i) halogen atom, (ii) hydroxy, (iii) carboxy, (iv) cyano, (v) C (vi) optionally halogenated C (vii) C (viii) C (ix) C (x) C (xi) carboxy-C (xii) C (xiii) C (xiv) C (xv) C (xvi) C (xvii) C (xviii) mono- or di-C (xix) (5- or 6-membered aromatic heterocycle)-carbonyl, (xx) mono- or di-C (xxi) (5- or 6-membered saturated cyclic amino)-carbonyl which may have carboxy, C (xxii) C (xxiii) C (xxiv) C (xxv) C (xxvi) C (xxvii) C (xxviii) (5- or 6-membered aromatic heterocycle)-thio, (xxix) amino which may have 1 or 2 substituent(s) selected from the group consisting of (a) C (xxxi) phthalimido, (xxxii) carbamoyl which may have 1 or 2 substituent(s) selected from the group consisting of (a) C (xxxiii) di-C (xxxiv) 5- or 6-membered aromatic heterocyclic group, (xxxv) phosphono which may have C (xxxvi) oxo; and n is 1 or 2; or a salt thereof.