Patent ID: 6509036
Filing Date: 2003-01-21
Classification: A61K,Y10S

Abstract:
A method for delivering a drug to a target area of the gastrointestinal tract of a mammal, said method comprising the steps of:(a) orally administering a dosage form comprising a therapeutically effective amount of a drug and at least one effervescent penetration enhancer in an amount sufficient to increase the penetration of said drug across said target area to permit absorption of said therapeutically effective amount of said drug, said amount of said effervescent penetration enhancer being greater than an amount necessary for rapid disintegration of said dosage form at said target area; (b) causing said drug and said effervescent penetration enhancer to release from said dosage form at said target area and to provide effervescent action at said target area thereby said effervescent action promotes said absorption of said therapeutically effective amount of said drug across said target area by said increased penetration of said drug across said target area.