Patent ID: 6890935
Filing Date: 2005-05-10
Classification: A61K,A61P,C07D

Abstract:
1. A compound of the formula: where X is carbon bonded to a substituent species selected from the group consisting of hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, heterocycyl, substituted heterocycly, cycloalkyl, substituted cycoalkyl, aryl, substituted aryl, alkylaryl, substituted alkylaryl; arylakyl, substituted arylaklyl, halo, —OR′, —NR′R″, —CF X′ is COR′ where R′ is selected from the group consisting of aryl, substituted aryl, heteroaryl, substituted heteroaryl, non-aromatic heterocyclyl, substituted non-aromatic heterocyclyl, non-aromatic heterocyclylalkyl and substituted non-aromatic heterocyclylalkyl; m is an integer and n is an integer such that the sum of m plus n is 0, 1, 2 or 3; E, E  where Z′ represents hydrogen or lower alkyl, acyl, alkoxycarbonyl, or aryloxycarbonyl; Z″ is hydrogen or lower alkyl; and Z′″ is a non-hydrogen substituent selected from the group consisting of alkyl, substituted alkyl, halo-substituted alkyl, cycloalkyl, substituted cycloalkyl, heterocyclyl, substituted heterocyclyl, aryl, substituted aryl, alkylaryl, substituted alkylaryl, arylalkyl and substituted arylalkyl; the dotted lines indicates a carbon-carbon single bond or a carbon-carbon double bond, p is 0, 1 or 2; q is 0, 1, 2, or 3; and j is an integer from 0 to 3, wherein Z′″j refers to j number of Z′″ substituents.