Patent ID: 8722659
Filing Date: 2014-05-13
Classification: A61P,C07D

Abstract:
1. A compound of formula (I): in which A represents either an oxygen or sulfur atom, or a sulfoxide function (SO function) or a sulfone function (SO 2 function); n represents the value 1; R a hydrogen atom, a halogen atom, a cyano group, a nitro group, an aryl, arylalkyl or heteroaryl group, a group (C a group —ORa, Ra being defined below, a group NRbRc, Rb and Rc being defined below, a group C(O)(C an alkenyl group or an alkynyl group, the said groups being optionally substituted with at least one hydroxyl or with at least one halogen atom; a group alkyl-S—, alkyl-S(O)—, and alkyl-S(O) given that R 3 represents: a hydrogen atom, a halogen atom, a hydroxyl group, a cyano group, a group —SCF a nitro group, a group —S(O) an alkyl-amino-alkyl group or a -cycloalkyl-amino-alkyl group, the said groups being optionally substituted on the terminal alkyl, an optionally substituted sulfonamide group, an aryl, arylalkyl or heteroaryl group, the said group being monocyclic or polycyclic and moreover being optionally substituted with a group (C a heterocycloalkyl group optionally substituted with a group (C a group (C a heterocycloalkyl group optionally substituted with a group CO(O)Ra, or with a group (C a group —C(O)NRbRc, Rb and Rc being defined below, a group —C(O)ORc, or a group —O—C(O)ORc, Rc being defined below, a group (C a group —O-cycloalkyl, —O-aryl or —O-arylalkyl, or a group —O-heterocycloalkyl, the said groups being optionally substituted with: a group —NH—CO—NH-aryl, a group —NH—CO—NH-arylalkyl, a group —NH—CO—NH-heteroaryl, or a group —NH—CO—NH—(C a group —N—(C a group —NH—C(O)-aryl, a group —NH—C(O)-aralkyl or a group —NH—C(O)-heteroaryl, the said groups being optionally substituted with at least one halogen atom; Rb represents: in the form of the base or of an acid-addition salt.