Patent ID: 6586193
Filing Date: 2003-07-01
Classification: C12Q,G01N,Y10S

Abstract:
A method for specific detection of one or more analytes in a sample, comprising the steps of:(a) providing a plurality of distinct populations of scattered-light detectable particles of a size between 1 and 500 nm inclusive, wherein each population specifically binds to a different predetermined analyte, and has a particle type configuration distinguishable from other populations by its predetermined scattered-light detectable property; (b) contacting the sample with said particles; (c) illuminating said particles using non-evanescent wave light under conditions which produce scattered light from said particle and in which light scattered from one or more said particles can be detected by a human eye with less than 500 times magnification and without electronic amplification; and (d) detecting light scattered by (i) said populations of particles bound with analyte under said conditions; or (ii) said populations of particles not bound with analyte under said conditions; or (iii) both (i) and (ii), as a measure of the presence of said bound analyte.