Patent ID: 6287875
Filing Date: 2001-09-11
Classification: G01N

Abstract:
A device for the detection of at least one analyte in a sample solution, comprising a solid support having:(a) a particle zone that contains particles containing a first member of an inverse ligand-receptor pair, a first member of a direct ligand-receptor pair, and a signal reagent; and(b) a first and a second signal zone wherein the first signal zone contains a second member of the inverse ligand-receptor pair and the second signal zone contains a second member of the direct ligand-receptor pairwherein:the analyte is a member of the inverse ligand-receptor pair or an analog thereof and is not a member of the direct ligand-receptor pair or analog thereof; andthe above elements are arranged in fluid communication, whereby the sample solution suspected of containing the analyte is introduced into the particle zone and then flows through the first and subsequently the second signal zone of each signal area whereby one or more predetermined concentrations of analyte can be discerned from a ratio of signals in the first and second signal zones.