Patent ID: 6749644
Filing Date: 2004-06-15
Classification: A61K,A61Q,C07C,C07D

Abstract:
A colorant for oxidative dyeing of keratin fibers, particularly human hair, based on a developer-coupler combination, said colorant containing, as developer, at least one 2-hydroxy-5-aminobiphenyl derivative compound of formula (I), or a physiologically tolerated, water-soluble salt thereof: wherein R1 denotes hydrogen, a halogen atom, a C1-C4-alkyl group, a C1-C4-hydroxyalkyl group, a C1-C4-alkoxy group or a C1-C4-hydroxyalkoxy group; wherein R2, R3, R4, R5, R6 can be equal or different and, independently of each other, denote hydrogen, a halogen atom, a cyano group, a hydroxy group, a C1-C4-alkoxy group, a C1-C4-hydroxyalkoxy group, a C1-C6-alkyl group, a C1-C4-alkyl thioether group, a mercapto group, a nitro group, an amino group, an alkylamino group, a dialkylamino group, a trifluoromethyl group, a â€”C(O)H group, a â€”C(O)CH3 group, a â€”C(O)CF3 group, an â€”SI(CH3)3 group, a C1-C4-hydroxyalkyl group, a C3-C4-dihydroxyalkyl group, a â€”CH&boxH;CHR7 group, a â€”(CH2)pâ€”CO2R8 group or a â€”(CH2)pâ€”R9 with p=1,2,3 or 4, a â€”C(R10)=NR11 or C(R12)Hâ€”NR13R14 group, or two adjacent R2 to R6 groups form an â€”Oâ€”CH2â€”Oâ€” bridge; R7 denotes hydrogen, a hydroxy group, a nitro group, an amine group, a â€”CO2R12 group or a â€”C(O)CH3 group; R8, R10 and R13 can be equal or different and, independently of each other, denote hydrogen or a C1-C4-alkyl group; R9 denotes an amino group or a nitrile group, R11, R14 and R15 can be equal or different and, independently of each other, denote hydrogen, a hydroxy group, a C1-C4-alkyl group, a C1-C4-hydroxyalkyl group, a C3-C4-dihydroxyalkyl group or a radical of formula R12 denotes hydrogen, an amino group or a hydroxy group, and provided that the at least one 2-hydroxy-5-aminobiphenyl derivative compound of the formula (I) does not have a center of symmetry and that, it one of R3 and R6 denotes an amino group, an alkylamino group or a dialkylamino group, another of R3 and R6 different from said one of R3 and R6 does not denote an amino group, an alkylamino group or a dialkylamino group.