Patent ID: 6180360
Filing Date: 2001-01-30
Classification: C12N,C12P

Abstract:
An isolated acyl-coenzyme A synthetase obtained from a filamentous fungus selected from the group consisting of Penicillium chrysogenum, Aspergillus nidulans, and Cephalosporium acremonium which, in the synthesis of the corresponding acyl-coenzyme A esters, is at least 10 times more active towards phenoxyacetic acid than towards acetic acid, and is at least 10 times more active toward phenylacetic acid than towards acetic acid,wherein said synthetase comprises a property selected from the group consisting of (a) an apparent molecular weight of between 40,000 and 60,000 Daltons as determined by gel filtration, (b) an apparent activity optimum in the range of pH 7.0-9.0, and (c) an apparent activity optimum in the temperature range of 35-45.degree. C.