Patent ID: 8263387
Filing Date: 2012-09-11
Classification: B01L,B03C,G01N

Abstract:
1. A sheath flow device comprising: (a) a first laminar flow establishing surface upstream of a sheath flow plane area configured to establish a sheath laminar flow in the sheath flow plane area; (b) a second laminar flow establishing surface parallel to the sheath flow plane area and upstream of a sample sheath flow plane area, wherein the second laminar flow establishing surface is configured to establish a sample laminar flow in the sheath flow plane area; and (c) a particle movement station configured to deflect a target species from the sample laminar flow and into the sheath laminar flow, wherein the particle movement station has a substantially rectangular interior space for bounding the sample laminar flow and the sheath laminar flow, wherein the interior space has first and second lateral dimensions transverse to the sample laminar flow, wherein the second lateral dimension is at least about 2 times larger than the first lateral dimension such that nonspecific binding is reduced along the larger of the first and second lateral dimensions.