Patent ID: 6111052
Filing Date: 2000-08-29
Classification: A61L,A61N,C08G

Abstract:
An implantable medical device comprising a biomaterial formed from a polymer substantially free of ester or ether linkages, the polymer comprising alternating soft and hard segments linked by urethane groups, urea groups, or combinations thereof, wherein:(a) the soft segments are of the formula:(--O or --OCNH)--(R.sup.a --U--R.sup.b --U).sub.y --R.sup.a --(O-- or NHCO--)wherein:(i) each R.sup.a and R.sup.b is independently a hydrocarbon moiety that can include linear, branched, cyclic structures, or combinations thereof, having a molecular weight of less than about 4000, wherein at least one R.sup.a or R.sup.b is noncrystallizing at ambient temperature;(ii) each U is independently a urethane group or a urea group; and(iii) y is the average number of repeating units, which is about 1-1000;(b) the hard segments are of the formula:(--O or --OCNH)--(R.sup.c --U--R.sup.d --U).sub.z --R.sup.c --(O-- or NHCO--)wherein:(i) each R.sup.c and R.sup.d is independently a hydrocarbon moiety that can include linear, branched, cyclic structures, or combinations thereof, having a molecular weight of less than about 1000, wherein at least one R.sup.c or R.sup.d is crystallizing at ambient temperature;(ii) each U is independently a urethane group or a urea group; and(iii) z is the average number of repeating units, which is about 1-1000; and(c) at least one of the soft segments or the hard segments includes a sulfur-containing or a phosphorus-containing moiety.