Patent ID: 6638750
Filing Date: 2003-10-28
Classification: A61K,C12N,C12Y

Abstract:
A purified nucleic acid encoding a protein having a methionine aminopeptidase (MetAP) type 3 (MetAP-3) activity selected from the group consisting of:(A) a nucleic acid comprising SEQ ID NO: 7, or its full complement, or a fragment thereof having a length of 300 to 1200 nucleotides; (B) a nucleic acid that specifically hybridizes under high stringency conditions to a nucleic acid of (A); (C) a nucleic acid encoding a protein having a sequence of SEQ ID NO: 8, or an enzymatically-active fragment of SEQ ID NO: 8 having a length greater than 100 contiguous amino acids; (D) a nucleic acid that specifically hybridizes under high stringency conditions to a nucleic of (C); and (E) A nucleic acid fragment of SEQ ID NO: 7, wherein said fragment is 300 to 1200 contiguous nucleotides in length and encodes a protein having MetAP3 activity.