Patent ID: 7402609
Filing Date: 2008-07-22
Classification: A61K,A61P,Y10S

Abstract:
1. A topically administrable solution composition for treating allergic or inflammatory disorders of the eye and nose, wherein the solution has a pH from 6.5-7.5 and a viscosity of 1-2 cps, and wherein the solution consists essentially of: a) 0.18-0.22% (w/v) olopatadine; b) 1.5-2% (w/v) polyvinylpyrrolidone having a weight average molecular weight of 50,000-60,000; c) a preservative selected from the group consisting of benzalkonium chloride; benzododecinum bromide; and polyquaternium-1; d) edetate disodium; e) a tonicity-adjusting agent selected from the group consisting of mannitol and sodium chloride; f) a buffering agent selected from the group consisting of phosphates and borates; g) optionally a pH-adjusting agent selected from the group consisting of NaOH and HCl; and h) water.