Patent ID: 8232430
Filing Date: 2012-07-31
Classification: B01J,C07B,C07C

Abstract:
1. A method for the production of cis-4-tertbutylcyclohexanol comprising contacting 4-tert-butylcyclohexanone with hydrogen gas, a catalyst comprising a ruthenium-aminophosphine complex and a base, wherein the complex is of the formula (I): wherein X is a suitable anionic ligand and may be the same or different; a is 1 or 2: b is 0 or 1, where a+b=2; (PNH (P 2 ) represents a diphosphine ligand of the formula III wherein R L is selected from C m is 1, 2 or 3; the optional substituents are selected from one or more of halo, OR R R wherein the cis-4-tertbutylcyclohexanol is prepared having a cis:trans ratio of 80:20 or more with respect to the cis isomer.