Patent ID: 7405267
Filing Date: 2008-07-29
Classification: C07K

Abstract:
1. A method for purifying teicoplanin A 2 comprising: (i) purifying a filtrate of a fermentation broth comprising teicoplanin A (ii) purifying the primary purification solution on a cation exchange resin having a cross-linkage of over 8% resin; a chelate resin; or a resin selected from the group consisting of acidic porous resins comprising a styrene polymer matrix, acidic cation exchange resins comprising a porous styrene polymer matrix, and gel-type acidic polymer resins, to create a secondary purification solution; (iii) purifying the secondary purification solution on a reversed phase resin, to create a tertiary teicoplanin A (iv) drying the tertiary teicoplanin A