Patent ID: 9075067
Filing Date: 2015-07-07
Classification: A61K,A61P,C12Q,G01N

Abstract:
1. A method for diagnosing a peritoneal carcinosis formed from a cancer cell from a gastric tumor that has disseminated to the abdominal cavity in a subject, comprising steps of: (a) providing a peritoneal tumor sample from the subject; (b) determining the level of expression in the peritoneal tumor sample of the phosphoglycerate kinase 1 (PGK1) gene, wherein the determining comprises (c) comparing the level of expression of the PGK1 gene in the peritoneal tumor sample to a level of expression of the PGK1 gene in a corresponding, non-malignant biological sample; and (d) diagnosing the peritoneal carcinosis as being formed from a cancer cell from a gastric tumor that has disseminated to the abdominal cavity based on a statistically significant overexpression of the PGK1 gene in the provided peritoneal tumor sample compared to the non-malignant biological sample.