Patent ID: 8211424
Filing Date: 2012-07-03
Classification: A61K,C12N,G01N

Abstract:
1. A method for treating a patient suffering from malignant melanoma, the method comprising: i) identifying in a patient one or more sentinel or metinel lymph nodes draining a malignant melanoma tumour or a metastasis from a malignant melanoma tumour; ii) resecting the one or more lymph nodes and, optionally all or part of the tumour or metastasis; iii) isolating tumour-reactive T-lymphocytes from said lymph nodes; iv) in vitro expanding said tumour-reactive T-lymphocytes, wherein the in vitro expansion comprises v) administering the thus obtained tumour-reactive T-lymphocytes to the patient; wherein the T-lymphocytes are CD4+ helper or CD8+ T-lymphocytes.