Patent ID: 7811568
Filing Date: 2010-10-12
Classification: A61K,A61P,C07K

Abstract:
1. A humanized monoclonal antibody comprising an antigen-binding domain directed against a B5R antigen comprising the amino acid sequence of SEQ ID NO: 7, wherein said antibody binds to the B5R antigen and wherein said antigen-binding domain comprises a heavy chain variable region comprising a first heavy chain CDR sequence identical to SEQ ID NO:1, a second heavy chain CDR sequence identical to SEQ ID NO:2, and a third heavy chain CDR sequence identical to SEQ ID NO:3 and a light chain variable region comprising a first light chain CDR sequence identical to SEQ ID NO:4, a second light chain CDR sequence identical to SEQ ID NO:5, and a third light chain CDR sequence identical to SEQ ID NO:6.