Patent ID: 7439336
Filing Date: 2008-10-21
Classification: C07K

Abstract:
1. A process for purifying interleukin-18 binding protein (IL-18BP) from a fluid comprising at least one step using aqueous two-phase partitioning that comprises a polyethylene glycol (PEG) phase and a (Na 2 )SO 4 salt phase, wherein the concentrations of PEG and (Na) 2 SO 4 in the two phases are calculated according to the following formula: wherein y=PEG in % [w/w] and x=(Na 2 )SO 4 in % [w/w]; wherein y=PEG in % [w/w] and x=(Na 2 )SO 4 in % [w/w]; or wherein y =PEG in % [w/w] and x=(Na 2 )SO 4 in % [w/w].