Patent ID: 8513028
Filing Date: 2013-08-20
Classification: A61P,C12Q

Abstract:
1. A method for screening a candidate substance as a candidate for treating rheumatoid arthritis, which comprises the steps of: (a) contacting a cell containing an MLN 51 (metastatic lymph node 51) gene or protein with a candidate substance to be analyzed, wherein the cell is a rheumatoid arthritis fibroblast-like synoviocyte; and (b) measuring the expression level of the MLN 51 gene, an amount of the MLN 51 protein, or an activity of the MLN 51 protein, wherein detection of a decrease in the expression level of the MLN 51 gene, the amount of the MLN 51 protein, or the activity of the MLN 51 protein compared to a control indicates that the candidate substance is a candidate for treating rheumatoid arthritis.