Patent ID: 6030940
Filing Date: 2000-02-29
Classification: A61K,C12N,C12Y

Abstract:
A linear 9 to 11 mer peptide selected from the group consisting of:LNFGQYLWYT (SEQ ID NO: 1),LCFGCYLWYT (SEQ ID NO: 2),LNFGCYLWCT (SEQ ID NO: 3),LNFGQYLnAYT (SEQ ID NO: 4),LNFdSQYLWYT (SEQ ID NO: 5),LCFGCYLWY (SEQ ID NO: 6),LNFdSQYLnAYT (SEQ ID NO: 7),LNFGdCYLWCT (SEQ ID NO: 8),LCFdSCYLWYT (SEQ ID NO: 9),LCFdSCYLnAYT (SEQ ID NO: 10),LNFdSCYLWCT (SEQ ID NO: 11),or an active 9 to 11 mer analog thereof, wherein the sequence of said active analog differs from the sequence of said peptide by 1 to 3 amino acid residues, and wherein said active analog exhibits a K.sub.d .ltoreq.250 nM with huPAR.