Patent ID: 6511966
Filing Date: 2003-01-28
Classification: A61K,A61P,C07C,C07D

Abstract:
A method for treating Alzheimer's Disease, Parkinson's Disease, diabetes mellitus, or stroke by administering to a warm-blooded animal in need thereof an effective amount of a compound having the following structure (III): or a steroisomer, prodrug or pharmaceutically acceptable salt thereof, whereinthe dotted line represents a single or double bond; A1 is selected from â€”H and C1-3alkyl; Y3 is â€”CORd; Z3 is selected from â€”H, C1-3alkyl and â€”(CH2)mX3Rd; X3 is selected at each occurrence from â€”Sâ€”, â€”Oâ€” and â€”NHâ€”; R3 is selected from â€”H, â€”CH3, â€”CH2CH3 and â€”Rd; Rd is selected from a guanidino moiety, a cylcoguanidino moiety, and a non-steroidal anti-inflammatory drug; and m is 1-4.