Patent ID: 6617320
Filing Date: 2003-09-09
Classification: A61P,C07D

Abstract:
A compound of formula I, whereinp represents 0, 1, 2, 3 or 4; q represents 0; R1 represents H, R2 represents H or C1-4 alkyl (which latter group is optionally substituted or terminated by one or more hydroxy group) R3 represents C3-8 cyclohexyl or phenyl (which latter two groups are optionally substituted by one or more of C1-4 alkyl, C1-4 alkoxy, halo, hydroxy, cyano, nitro, methylenedioxy, trifluoromethyl, N(H)R27 or C(O)OR28; R27 represents H, C1-4 alkyl or C(O)R29; R28 and R29 independently represent H or C1-4 alkyl; R4 represents H or C1-4 alkyl; Y represents CH2 n represents 1, 2, 3 or 4; and B represents a structural fragment of formula IVa whereinR5 represents H, halo or C1-4 alkyl; or a pharmaceutically acceptable salt thereof.