Patent ID: 7678552
Filing Date: 2010-03-16
Classification: A61P,G01N

Abstract:
1. A method for determining the efficacy of a candidate chemotherapy for a patient prior to treatment, comprising the steps of: separating a cancer patient's tissue specimen into multicellular particulates, wherein the patient's tissue specimen comprises tumor tissue and the multicellular particulates are not dissociated cell suspensions, wherein the tumor tissue is an ovarian carcinoma tumor, a breast carcinoma tumor, a renal carcinoma tumor, or a mesothelioma; allowing said cohesive multicellular particulates to form one or more tissue culture monolayer(s) comprising growing malignant cells without overgrowth of fibroblasts; suspending cells of the monolayer(s) in a plurality of segregated sites; and screening the cells in the segregated sites for sensitivity to a plurality of candidate chemotherapies indicated for treatment of said cancer, thereby determining the efficacy of each candidate chemotherapy for the patient prior to treatment.