Patent ID: 6248531
Filing Date: 2001-06-19
Classification: A61K,C07F,C07H,G01N

Abstract:
A method for labeling a bio-organic molecule, comprising the steps of(i) providing a trans-platinum compound, having the formula: ##STR4##wherein A and D represent reactive moieties that are the same or different, and X.sub.1 and X.sub.2 are the same or different and are selected from the group consisting of NH.sub.3, NH.sub.2 R, NHRR' and NRR'R"" groups wherein R, R' and R"" each represent an alkyl group having from 1 to 6 carbon atoms;(ii) replacing one reactive moiety of said trans-platinum based compound with a label; and(iii) replacing the other reactive moiety of said trans-platinum based compound with the bio-organic molecule.