Patent ID: 8017324
Filing Date: 2011-09-13
Classification: A01K,C12N,C12Q,G01N

Abstract:
1. Method for determining if a human subject is at increased risk to develop obesity or type 2 diabetes, said method comprising the steps of: a) obtaining a biological sample from said human subject, wherein said biological sample contains genomic DNA or RNA; b) performing a nucleic acid detection assay to detect in the biological sample the presence or absence of a three allele risk haplotype on at least one gene allele or RNA sequence encoding the protein ENPP1, wherein said three allele risk haplotype comprises the three following SNPs: c) determining whether or not the human subject is at increased risk to develop obesity or type 2 diabetes by observing if said DNA or RNA, or fragments thereof, contains said three allele risk haplotype, wherein the presence of said three allele risk haplotype indicates that said human subject is at increased risk to develop obesity or type 2 diabetes.