Patent ID: 6350731
Filing Date: 2002-02-26
Classification: A61K,C07K

Abstract:
A platelet-derived growth factor peptide analogue consisting essentially of:(i) a first sequence selected from the group consisting of: 25I-S-R-R-L-I-D-R-T-N-A-N-F-L38(GP1) (SEQID NO:1)Ac-25I-S-R-R-L-I-D-R-T-N-A-N-F-L38(GP2) (SEQID NO:1)25I-S-R-R-L-I-D-R-T-N-A-N-F-L38-C(GP3) (SEQID NO:2)Ac-25I-S-R-R-L-I-D-R-T-N-A-N-F-L38-C(GP4) (SEQID NO:2)25I-S-R-R-L-I-D-R-T-N-A-N-F-L-V-W-P-P-C43(GP9) (SEQID NO:3)andAc-25I-S-R-R-L-I-D-R-T-N-A-N-F-L-V-W-P-P-C43(GP10) (SEQID NO:3);(ii) a second sequence linked to the first sequence and selected from the group consisting of: 73R-K-I-E-I-V-R-K-K81(GP5) (SEQ ID NO:4)Ac-73R-K-I-E-I-V-R-K-K81(GP6) (SEQ ID NO:4)73R-K-I-E-I-V-R-K-K81-C(GP7) (SEQ ID NO:5)Ac-73R-K-I-E-I-V-R-K-K81-C(GP8) (SEQ ID NO:5)73R-K-I-E-I-V-R-K-K-P-I-F-K-K-A-T-V89(GP21a) (SEQ IDNO:6)73R-K-I-E-I-V-R-K-K-P-I-F-K-K-A-T-V89-C(GP21) (SEQ IDNO:7)andAc-73R-K-I-E-I-V-R-K-K-P-I-F-K-K-A-T-V89-C(GP22) (SEQ IDNO:7).