Patent ID: 9102734
Filing Date: 2015-08-11
Classification: A61K,A61P,C07K,Y02A

Abstract:
1. A fusion protein comprising the formula: wherein Ab is an antibody or antigen binding fragment thereof; PL is at least one peptide linker comprising at least one glycosylation site; Ag is at least one cancer antigen; and x is an integer from 1 to 20, wherein the Ag is selected from tumor associated antigens selected from human papilloma virus (HPV) E6 and E7 and the PL is selected from SSVSPTTSVHPTPTSVPPTPTKSSP (SEQ ID NO.: 11), PTSTPADSSTITPTATPTATPTIKG (SEQ ID NO.: 12), TVTPTATATPSAIVTTITPTATTKP (SEQ ID NO.: 13) and TNGSITVAATAPTVTPTVNATPSAA (SEQ ID NO.: 14).