Patent ID: 6271379
Filing Date: 2001-08-07
Classification: C07D

Abstract:
A compound represented by the formula: ##STR25##wherein:R.sup.1 is lower alkyl, benzyl, or substituted benzyl;Y is selected from the group consisting of --NO.sub.2, --NHR.sup.2, --NR.sup.3 R.sup.4, --CH.dbd.NOR.sup.5, --COR.sup.6, --COCl, --C(O)NR.sup.6 R.sup.7, --CN, --C(S)NR.sup.6 R.sup.7, --N.sub.3, --SR.sup.6, and --N.dbd.CR.sup.8 R.sup.9 ;R.sup.2 is an amino protecting group;R.sup.3 and R.sup.4 are independently selected from the group consisting of --C(O)OR.sup.10, --C(O)R.sup.10, allyl, benzyl, substituted benzyl, phenacyl, and 3-acetoxypropyl or R.sup.3 and R.sup.4 may be taken together to form a cyclic imide;R.sup.5 is selected from the group consisting of hydrogen, lower alkyl, and aryl;R.sup.6 and R.sup.7 are independently selected from the group consisting of hydrogen, lower alkyl, substituted lower alkyl, aryl, and substituted aryl or R.sup.6 and R.sup.7 may be taken together to form a heterocyclic ring;R.sup.8 and R.sup.9 are independently selected from the group consisting of hydrogen, lower alkyl, substituted lower alkyl, aryl, and substituted aryl or R.sup.8 and R.sup.9 may be taken together to form a ring;R.sup.10 is selected from the group consisting of lower alkyl, substituted lower alkyl, aryl, substituted aryl, adamantyl, cinnamyl, 2-trimethylsilylethyl, 2-phenylethyl, vinyl, allyl, benzyl, and substituted benzyl; andone broken line is present as a carbon--carbon bond and the other broken line is absent, where the broken line completes an unconjugated carbon--carbon double bond, which double bond is endocyclic whereby n is 3 or the double bond is exocyclic whereby n is 2.