Patent ID: 7005417
Filing Date: 2006-02-28
Classification: A61K,A61P,C07K

Abstract:
1. A compound selected from the group consisting of all possible steroisomeric forms and their mixtures of a compound of the formula wherein either R 1 and R 2 are individually selected from the group consisting of hydrogen, hydroxyl, alkyl and cycloalkyl of up to 8 carbon atoms optionally interrupted by oxygen and optionally substituted by a member selected from the group consisting of are individually hydrogen or alkyl of 1 to 8 carbon atoms or R 1 forms with the endocyclic carbon atom carrying a double bond and R2 is —XRa, X is selected from the group consisting of oxygen, —NH— or —N-alkyl of 1 to 8 carbon atoms and Ra is selected from the group consisting of hydrogen, alkyl or cycloalkyl of up to 8 carbon atoms substituted by at least one member of the group consisting of halogen, —OH, —CO 2 H, —CO 2 alk, a′ and b′ are hydrogen or alkyl of 1 to 8 carbon atoms or R 2 is in which d, e, f and g are hydrogen or alkyl of 1 to 8 carbon atoms, f and g can also be acyl of up-to 8 carbon atoms, R R R is selected from the group consisting of T is selected from the group consisting of hydrogen, methyl, —CH Y is selected from the group consisting of hydrogen, hydroxyl, halogen and OSO W is hydrogen or —OH, Z is hydrogen or methyl and a non-toxic, pharmaceutically acceptable acid addition salt thereof.