Patent ID: 8394927
Filing Date: 2013-03-12
Classification: A61K,A61P,C07K,C12N,G01N

Abstract:
1. An isolated antibody that binds to the extracellular domain of FGFR4 or an antigen binding fragment thereof, wherein the antibody or antigen binding fragment comprises at least one heavy chain amino acid sequence comprising the following CDRs: a CDRH1 as shown in SEQ ID NO: 9, (b) a CDRH2 as shown in SEQ ID NO: 10, and (c) a CDRH3 as shown in SEQ ID NO: 11, and at least one light chain amino acid sequence comprising the following CDRs: a CDRL1 as shown in SEQ ID NO: 12, (e) a CDRL2 as shown in SEQ ID NO: 13, and a CDRL3 as shown in SEQ ID NO: 14.