Patent ID: 7071195
Filing Date: 2006-07-04
Classification: A61P,C07C,C07D

Abstract:
1. A compound of the formula wherein R R B B Y is methylene or carbonyl; L is selected from the group consisting of R R R R n is 1–2; m is 0–3; p is 1–3; and q is 1–3; provided that when L is (N-methylene)piperazin-4-yl, then Z is phenyl or naphthyl; when L is (N-methylene)piperidin-4-yl, then Z is N-sulfonamido, N(aryl)sulfonamido, 2,3-dihydro-2-oxo-1H-benzimidazol-1-yl, benzamido, phenylureido, phenylacetamido or (phenoxy)carbonylamino; when L is (N-methylene)-4-acetyl-piperidin-4-yl, then Z is phenyl or naphthyl and Y is carbonyl; and when L is (N-methylene)piperidin-4,4-diyl, then Z is 1-aryl-2,3-dihydro-4-oxo-imidazol-5,5-diyl and Y is carbonyl; and enantiomers, diastereomers and pharamaceutically acceptable salts thereof.