Patent ID: 8148389
Filing Date: 2012-04-03
Classification: A61K,A61P,C07D

Abstract:
1. A method of promoting proliferation of a corneal epithelial cell, comprising administering an effective amount of a PPARα or δ agonist to a subject in need of promotion of proliferation of a corneal epithelial cell, wherein the PPARα or δ agonist is a compound represented by the formula (I): wherein A is a hydrogen atom or an alkyl group having a carbon number of 1 to 6, B is a linker selected from the group consisting of —CO—, —NH—, —(CH X and Y are the same or different, and each is a carbon atom or a nitrogen atom, Z is an oxygen atom, a sulfur atom or —CH Ar R R or a pharmacologically acceptable salt thereof.