Patent ID: 7135502
Filing Date: 2006-11-14
Classification: A61K,A61P

Abstract:
1. A compound of the formula IIa: wherein X is —CH(R 7 )— wherein R 7 is hydrogen, hydroxy, C 1-7 alkoxy, —OR 8 or —NR 8 R 9 , wherein R 8 is a group —Y 1 R 10 , wherein Y R R R 1 , R 2 and R 3 are each independently hydrogen, PO 3 H 2 , sulphate, C 3-7 cycloalkyl, C 2-7 alkenyl, C 2-7 alkynyl, C 1-7 alkanoyl, a group R 20 C 1-7 alkyl (wherein R 20 is phenyl which may bear one or more substituents selected from C 1-4 alkyl, C 1-4 alkoxy, C 1-4 aminoalkyl and C 1-4 hydroxyalkoxy), C 1-7 alkyl or C 1-7 alkylsulphonyl, which alkyl or alkylsulphonyl group may bear one or more substituents selected from: halogeno, amino, C with the proviso that at least two of R R 4 is hydrogen, cyano, halogeno, nitro, amino, hydroxy, C 1-7 alkoxy, C 1-7 thioalkoxy, C 1-7 alkanoyl or C 1-7 alkyl, which alkyl group may bear one or more substituents selected from: halogeno, amino, C R 5 and R 6 are each independently selected from hydrogen, —OPO 3 H 2 , phosphonate, cyano, halogeno, nitro, amino, carboxy, carbamoyl, hydroxy, C 1-7 alkoxy, C 1-7 alkanoyl, C 1-7 thioalkoxy, C 1-7 alkyl, which alkyl group may bear one or more substituents selected from: halogeno, amino, C a group —Y with the proviso that R with the further proviso that at least one of R that when R that when R or a salt thereof.