Patent ID: 6248359
Filing Date: 2001-06-19
Classification: A61K,A61P

Abstract:
A two-tablet system for treating urinary incontinence in a mammal, the system comprising:a first tablet comprising a first oxybutynin charge which is released after at least about one second up to less than about twelve hours after administration of the first tablet; anda second tablet comprising a second oxybutnin charge which is released after at least about three hours up to less than about thirty hours after administration of the second tablet, wherein the first and second tablet together provide a sustained delivery of oxybutynin for a total period of about 18-30 hours, the system maintains therapeutic levels of oxybutynin for a period of about 18 to 24 hours, and the first and second tablets are administered on a once daily basis;wherein each tablet exhibits a different profile and the system provides reduced side effects as compared to a conventional system providing the same therapeutic dose.