Patent ID: 7838697
Filing Date: 2010-11-23
Classification: C07F

Abstract:
1. A method of manufacturing an organoboron compound as shown by below-listed general formula (3) or general formula (4), the method comprising: coupling, in the presence of a catalyst having a chiral phosphine ligand, which chiral phosphine ligand is an optically active phosphine as shown by general formula (6) where R where R represents a hydrogen atom, an alkyl group, a substituted alkyl group, a cycloalkyl group, a substituted cycloalkyl group, an aralkyl group, a substituted aralkyl group, an aryl group, a substituted aryl group, an aliphatic heterocyclic group, a substituted aliphatic heterocyclic group, an aromatic heterocyclic group, a substituted aromatic heterocyclic group, an alkoxy group, a substituted alkoxy group, an aralkyloxy group, a substituted aralkyloxy group, an aryloxy group, a substituted aryloxy group, an alkyloxy carbonyl group, an aralkyloxy carbonyl group, or a substituted silyl group; E is an elimination group, and represents a carbonate ester, a carboxylate ester, a phosphate ester or a sulfonate ester; and the wavy line represents that either a trans- or a cis-isomer is possible; where X represents identical or different atoms selected from oxygen or nitrogen; the dotted lines connecting adjacent Xs represent that other atoms are bound to Xs; and adjacent Xs may form a ring via other atoms; where R represents an alkyl group, a substituted alkyl group, a cycloalkyl group, a substituted cycloalkyl group, an aralkyl group, a substituted aralkyl group, an aryl group, a substituted aryl group, an aliphatic heterocyclic group, a substituted aliphatic heterocyclic group, an aromatic heterocyclic group, a substituted aromatic heterocyclic group, an alkoxy group, a substituted alkoxy group, an aralkyloxy group, a substituted aralkyloxy group, an aryloxy group, a substituted aryloxy group, an alkyloxy carbonyl group, an aralkyloxy carbonyl group, or a substituted silyl group; X represents identical or different atoms selected from oxygen or nitrogen; the dotted lines connecting adjacent Xs represent that other atoms are bound to Xs; and adjacent Xs may form a ring via other atoms; and * represents a chiral carbon; where R represents an alkyl group, a substituted alkyl group, a cycloalkyl group, a substituted cycloalkyl group, an aralkyl group, a substituted aralkyl group, an aryl group, a substituted aryl group, an aliphatic heterocyclic group, a substituted aliphatic heterocyclic group, an aromatic heterocyclic group, a substituted aromatic heterocyclic group, an alkoxy group, a substituted alkoxy group, an aralkyloxy group, a substituted aralkyloxy group, an aryloxy group, a substituted aryloxy group, an alkyloxy carbonyl group, an aralkyloxy carbonyl group, or a substituted silyl group; X represents identical or different atoms selected from oxygen or nitrogen; the dotted lines connecting adjacent Xs represent that other atoms are bound to Xs; and adjacent Xs may form a ring via other atoms; * represents a chiral carbon; and the wavy line represents that either a trans- or a cis-isomer is possible.