Patent ID: 6083922
Filing Date: 2000-07-04
Classification: A61K,A61P,Y10S

Abstract:
A method for treatment and containment of infectivity of pulmonary tuberculosis by providing a patient in need of such treatment an aerosol formulation comprising aerosolized tobramycin, said method comprising a step:(a) administering to the patient a nebulized aerosol formulation consisting essentially of from about 40 to about 800 mg tobramycin dissolved in full strength or diluted saline adjusted to pH between 5.5 and 7.0 using a nebulizer producing an aerosolized tobramycin of particles sizes of which a mass medium average diameter is predominantly between 1 and 5.mu. once or twice daily at least until a count of Mycobacterium tuberculosis decreases to less than 10.sup.3.