Patent ID: 6794534
Filing Date: 2004-09-21
Classification: C07B,C07C,C07D

Abstract:
A method for preparing trisubstituted olefins comprising:contacting a geminal disubstituted olefin with a terminal olefin in the presence of a metal carbene metathesis catalyst of the formula XX1LL1M=CRR1 to generate a tri-substituted olefin in an intermolecular olefin cross-metathesis reaction, wherein: M is ruthenium or osmium; L and L1 are each, independently, any neutral electron donor; X and X1 are each, independently, any anionic ligand; and R and R1 are each independently selected from hydrogen or a substituent selected from the group consisting of C1-C20 alkyl, C2-C20 alkenyl, C2-C20 alkenyl, aryl, C1-C20 carboxylate, C1-C20 alkoxy, C2-C20, alkenyloxy, aryloxy, C2-C20 alkoxycarbonyl, C1-C20 alkylthiol, aryl thiol, C1-C20 alkylsulfonyl and C1-C20 alkylsulfinyl, the substituent optionally substituted with one or more moieties selected from the group consisting of C1-C20 alkyl, C1-C20 alkoxy, aryl, and a functional group selected from the group consisting of hydroxyl, thiol, thioether, ketone, aldehyde, ester, ether, amine, imine, amide, nitro, carboxylic acid, disulfide, carbonate, isocyanate, carbodiimide, carboalkoxy, carbamate, and halogen.