Patent ID: 6617348
Filing Date: 2003-09-09
Classification: A61P,C07D

Abstract:
A composition comprising a compound of formula: wherein E is selected from the group consisting of: X&boxH;O, S, NR2; Y&boxH;CH2, O, S, NR2; Q&boxH;O, NH; F=ortho, meta, para substituents including halogen, CN, OR2, OC(O)R3, NO2, OSO2R3, NR2R2, NR2C(O)R3, NR2SO2R3, R3; R1&boxH;H, Me; R2&boxH;R1, straight chain saturated alkyl, straight chain unsaturated alkyl, branched chain alkyl, branched chain unsaturated alkyl, cycloalkyl, aryl, heteroaryl, heterocycle, CH2aryl, CH2 heteroaryl, CH2 heterocycle, CHR1CHR1, CHR1CHR1heteroaryl, CHR1CHR1heterocycle; R3&boxH;R2 or CR1&boxH;CR1aryl, CR1&boxH;CR1heteroaryl, CR1&boxH;CR1heterocycle, Câ‰¡Caryl, Câ‰¡Cheteroaryl, Câ‰¡Cheterocycle; and Z is a contiguous linker whose presence completes an 11 to 15 membered ring.