Patent ID: 6472406
Filing Date: 2002-10-29
Classification: A61P,C07F

Abstract:
A compound of Formula (I): or a pro-drug or pharmaceutically acceptable salt thereof, whereinR1 is aryl or heteroaryl, wherein the aryl or heteroaryl group may be optionally substituted; n is 0, 1, or 2; R2 is selected from the group consisting of hydrogen, alkyl, cycloalkyl, aralkyl, and aryl, wherein the aryl portion of any such group may be optionally substituted; R3 is selected from the group consisting of hydrogen, alkyl, cycloalkyl, aralkyl, aryl, heteroaryl, and (heteroaryl) alkyl, any of which groups may be optionally substituted; R4 is OH; R5 is OR6; R6 is selected from the group consisting of aryl, pyridyl, quinolyl, or isoquinolyl, any of which may be optionally substituted; provided that R6 is not unsubstituted phenyl; and further provided that R1 is not 5-dimethylamino-1-naphthyl when R2 and R3 are both H, and R5 is 4-nitrophenoxy.