Patent ID: 8552057
Filing Date: 2013-10-08
Classification: A61K,A61P

Abstract:
1. A method for alleviating or preventing hot flashes in a patient comprising administering to the patient an effective amount of a formulation consisting of two or more phytoestrogen compounds or analogues thereof that selectively bind to estrogen receptor beta and cross the blood brain barrier, in a pharmaceutically acceptable excipient, wherein the patient is a menopausal or post-menopausal woman; the two or more phytoestrogen compounds are selected from the group consisting of genistein, daidzein, equol, IBSO03569, and combinations thereof, and are administered in an effective amount from about 1 mg/kg/day to about 10 mg/kg/day; and the phytoestrogen compounds are more effective in combination than the same amount of the individual phytoestrogen compounds.