Patent ID: 7097851
Filing Date: 2006-08-29
Classification: A61K,A61P

Abstract:
1. An oral formulation for gastrointestinal drug delivery which comprises an adhesion site-controlling layer for attaching the formulation to a selected site in the intestines, a drug-carrying layer containing a drug and an adhesive to attach the drug containing layer to the selected site in the intestines when the adhesion site-controlling layer dissolves at the selected site in the intestines, and a protecting layer structured and arranged for preventing digestive juice from permeating into the drug-carrying layer and the drug-carrying layer from releasing the drug through the protecting layer, the drug-carrying layer existing between the protecting layer and the adhesion site-controlling layer, the adhesion site-controlling layer is attached to the protecting layer and the adhesion site-controlling layer is a film made of an enteric polymer, and the adhesion site-controlling layer contains a plasticizer.