Patent ID: 7316910
Filing Date: 2008-01-08
Classification: C12Q,G01N

Abstract:
1. A process for detecting streptokinase produced by a beta-hemolytic streptococcus bacterium in a host consisting of: collecting a biological fluid sample from the host, said biological fluid sample containing host plasminogen and the streptokinase; contacting said biological fluid sample with a first reagent comprising a proteinaceous substrate for an active enzyme, said active enzyme being selected from the group consisting of streptokinase-plasminogen complex, streptokinase-plasmin, and plasmin; discerning a color change after the contacting step, to indicate the streptokinase is present in the host, the color change being due to said proteinaceous substrate being cleaved by the active enzyme to yield a colored dye; and optionally introducing plasminogen to said fluid in a reagent formula.