Patent ID: 7291614
Filing Date: 2007-11-06
Classification: A61K,A61P,C07D

Abstract:
1. A process for preparation of S—N-(4-morpholinyl-3-fluorophenyl)-2-oxo-5-oxazolidinyl-methyl amine (II) from R—N-(4-morpholinyl-3-fluorophenyl)-2-oxo-5-oxazolidinyl-methyl azide (III) by catalytic hydrogenation comprising: (a) combining R—N-(4-morpholinyl-3-fluorophenyl)-2-oxo-5-oxazolidinyl-methyl azide (III) with an organic solvent other than ethyl acetate selected from the group consisting of: (b) inducing catalytic hydrogenation of the said azide (III) mixture to obtain S—N-(4-morpholinyl-3-fluorophenyl)-2-oxo-5-oxazolidinyl-methyl amine (II).