Patent ID: 6608099
Filing Date: 2003-08-19
Classification: A61P,C07D

Abstract:
An indole compound represented by the formula (I), or a pharmaceutically acceptable salt, or solvate derivative thereof; wherein;R1 is the group â€”(L1)â€”R11, where, â€”(L1)â€” is â€”(CH2)â€” and R11 is C7-C20 alkyl, C7-C20 haloalkyl, C7-C20 alkenyl, C7-C20 alkynyl, or a carbocyclic radical; R2 is â€”CH3 or C2H5; R3 is â€”C(O)â€”C(O)â€”NH2; R4 is the group â€”(La)-(acylsulfonamide group) where â€”(La)â€” is â€”Oâ€”CH2â€” and the acylsulfonamide group is â€”C(O)â€”CHâ€”S(O)(O)â€”R81 and R81 is â€”CF3, CH3 or C2H5; R5 is hydrogen; and R6 and R7 are hydrogen, or a carbocyclic radical.