Patent ID: 6126909
Filing Date: 2000-10-03
Classification: A61K,A61P,G21G

Abstract:
A process for producing substantially radio-impurity-free Bi-212 comprising the steps of:(a) contacting an acidic Pb-212 feed solution with an extraction medium having a plurality of binding sites thereon adapted to bind said Pb-212 thereto, to form a Pb-212-laden extraction medium and less strongly bound contaminants;(b) rinsing said Pb-212-laden extraction medium with a second acid solution to remove the less strongly bond contaminants therefrom and to form a substantially impurity-free Pb-212-laden extraction medium;(c) maintaining said substantially radio-impurity-free Pb-212-laden extraction medium for a predetermined period of time so as to form Bi-212 from said Pb-212 by radioactive decay;(d) introducing a third acid solution to said substantially impurity-free Pb-212-laden extraction medium to release said Bi-212 therefrom and form a Bi-212 acid solution; and(e) eluting said Bi-212 acid solution from said substantially impurity free Pb-212-laden extraction medium to form a substantially radio-impurity free Bi-212 acid solution.