Patent ID: 8975449
Filing Date: 2015-03-10
Classification: C07C,C07D

Abstract:
1. A method of preparing chlorohydrins by reacting polyhydroxy aliphatic hydrocarbon with a chlorination agent in the presence of a catalyst, the method comprising at least one combination of a series of unit operations comprising a plurality of reaction steps and a water removal step in the following stated order: a first reaction step of reacting the polyhydroxy aliphatic hydrocarbon with the chlorination agent; a water removal step of removing water as a by-product from a reaction mixture discharged from the first reaction step; and a second reaction step of reacting at least one constituent of the dehydrated reaction mixture with at least one of the chlorination agent and an additional chlorination agent, wherein at least a portion of a reaction mixture discharged from at least one reaction steps from among the plurality of reaction steps is mixed with an additional chlorination agent, and the resulting mixture is then recirculated to the reaction step from which the reaction mixture was discharged, wherein the catalyst comprises at least one selected from the group consisting of an organic acid catalyst, a carboxylic acid-based catalyst, a nitrile-based catalyst, and a solid catalyst, wherein the effluent of the first reactor introduced into the water removal step comprises the chlorination agent and water at a ratio of 10 to 25.0 parts by weight of the total of the chlorination agent and the additional chlorination agent and 75 to 90 parts by weight of water so that the effluent of the first reactor introduced into the water removal step forms an azeotropic mixture.