Patent ID: 8361441
Filing Date: 2013-01-29
Classification: A61K,C07K,G01N

Abstract:
1. A method for the treatment of bacterial infection caused by Escherichia coli, Shigella sonnei, Shigella flexneri, Salmonella typhi, Salmonella group A, Salmonella group B, Salmonella group D, Citrobacter freundii, Citrobacter koseri, Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter aerogenes, Enterobacter cloacae or Serratia marcescens in central nervous system and/or peripheral blood circulation in a mammal, which comprises administering to said mammal an effective amount of an outer membrane protein A (OmpA) from Escherichia coli, Shigella sonnei, Shigella flexneri, Salmonella typhi, Salmonella group A, Salmonella group B, Salmonella group D, Citrobacter freundii, Citrobacter koseri, Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter aerogenes, Enterobacter cloacae or Serratia marcescens.