Patent ID: 7935784
Filing Date: 2011-05-03
Classification: A61P,C07K,Y10T

Abstract:
1. An isolated polypeptide, comprising SEQ ID NO:1, or a fragment of SEQ ID NO:1 of 50 to 79 contiguous amino acid residues in length; wherein in reference to the contiguous amino acid positions of SEQ ID NO:1: Xaa at position 2 is Thr or Ser, Xaa at position 5 is Leu or Pro, Xaa at position 6 is Pro or Leu, Xaa at position 16 is Leu or Gln, Xaa at position 18 is Met or Leu, Xaa at position 21 is Gly, Asp, Ala, or Val, Xaa at position 36 is Leu or Ile, Xaa at position 54 is Pro or Arg, Xaa at position 64 is Pro or Leu, and Xaa at position 73 is Asp or Asn; and wherein the polypeptide additionally comprises a variant residue selected from among Cys at position 17 or Ile at position 31 of SEQ ID NO:1.