Patent ID: 6331629
Filing Date: 2001-12-18
Classification: C07D

Abstract:
A compound of the formula: ##STR35##or a pharmaceutically acceptable addition salt thereof, wherein:R.sub.c represents hydrogen, halogen or C.sub.1 -C.sub.6 alkyl;R.sub.1 and R.sub.2 independently represent hydrogen, halogen, hydroxy, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.4 alkoxy, trifluoromethyl, trifluoromethoxy or SO.sub.2 NH.sub.2,provided that, when R.sub.3 and R.sub.4 are both hydrogen,R.sub.1 and R.sub.2 are not hydrogen simultaneously; andprovided that, R.sub.1 and R.sub.2 cannot both be hydrogen simultaneously, and provided that when R.sub.1 is C.sub.1 -C.sub.4 alkyl or halogen, R.sub.2 is halogen, hydroxy, C.sub.2 -C.sub.6 alkyl, trifluoromethyl, trifluoromethoxy or SO.sub.2 NH.sub.2 ; orR.sub.1 and R.sub.2 together represent a C.sub.1 -C.sub.2 alkylene dioxy group or a C.sub.1 -C.sub.3 alkylene oxy group; and provided that when R.sub.1 and R.sub.2 together represent a C.sub.1 -C.sub.2 alkylene dioxy group or a C.sub.1 -C.sub.3 alkylene oxy group, at least one of R.sub.3 and R.sub.4 is halogen or C.sub.2 -C.sub.6 alkyl;R.sub.3 and R.sub.4 are the same or different and represent hydrogen, halogen, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.4 alkoxy, alkylthio, hydroxy, amino, mono or dialkyl amino where each alkyl is C.sub.1 -C.sub.6 alkyl, cyano or trifluoromethyl; with the proviso that when either R.sub.3 or R.sub.4 is methyl, then the other is halogen, C.sub.2 -C.sub.6 alkyl, C.sub.1 -C.sub.4 alkoxy, alkylthio, hydroxy, amino, mono or dialkyl amino where each alkyl is C.sub.1 -C.sub.6 alkyl, cyano or trifluoromethyl; andR.sub.6 and R.sub.7 independently represent hydrogen or C.sub.1 -C.sub.6 alkyl.