Patent ID: 6806090
Filing Date: 2004-10-19
Classification: G01N,G01R,Y10T

Abstract:
A process of establishing a standard specification for a medicinal plant material, the process comprising:(i) selecting a sample of the medicinal plant material, which sample is known to possess a particular desired property, as a standard sample; (ii) preparing a test solution or test extract of said standard sample; (iii) submitting said solution or extract to two or more analytical methods including (a) a combination of NMR spectroscopy and computer-based pattern recognition, said combination comprising submitting the solution or extract to NMR spectroscopy, recording one or more NMR spectra and submitting data obtained from the or each NMR spectrum to a multivariate analysis, and (b) one or more biological profiling techniques which provide a quantifiable measure of the biological effect of the plant and which include proteomics; (iv) obtaining results from the analytical methods used in step (iii); and (v) defining a standard specification for the said plant material on the basis of the results obtained in step (iv); the process being conducted such that the NMR data submitted to the multivariate analysis reflect the totality of the compounds in the plant material which respond to the NMR technique being used.