Patent ID: 8816093
Filing Date: 2014-08-26
Classification: C07D

Abstract:
1. A process for preparing a compound of formula 1: comprising the step of: wherein, R is H, C R R o is an integer from 0 to 3 inclusive; and p is an integer from 0 to 5 inclusive; with a compound of formula 7a: wherein, A is a fused cycloalkyl, or heterocycloalkyl ring; R R m is an integer from 0 to 3 inclusive; n is an integer from 1 to 4 inclusive; and X is a halo or OH; in an organic solvent in the presence of a second base, wherein compound 7a is prepared by the following steps wherein, A is a fused cycloalkyl or heterocycloalkyl ring; R R R m is an integer from 0 to 3 inclusive, with a reducing agent to produce Compound 11a: wherein, ring A, R wherein, ring A, R wherein, ring A, R wherein, Hal is a halide; and q is an integer from 0 to 3 inclusive; to produce a compound of formula 14a: wherein, r is an integer from 1 to 4 inclusive; and ring A, R wherein, r, ring A, R wherein, Hal is halide; and r, ring A, R