Patent ID: 8940291
Filing Date: 2015-01-27
Classification: A61K,A61P,C07C,C07D,C12N

Abstract:
1. A method of enhancing the production of a virus in cells comprising: producing a composition comprising the virus and a viral sensitizing agent by administering the viral sensitizing agent to said cells prior to, after, or concurrently with the virus; and culturing the virus and cells to enhance the production of the virus in said cells; wherein the viral sensitizing agent is of the formula: or an N-oxide, pharmaceutically acceptable addition salt, quaternary amine, or stereochemically isomeric form thereof, wherein: A is a 5-membered heterocyclic ring comprising 1-4 heteroatoms selected from O, N, and S and 1 or 2 double bonds; R R R R