Patent ID: 8299087
Filing Date: 2012-10-30
Classification: A61K,A61P,C07D

Abstract:
1. A method of inhibiting an activity of a JAK kinase, comprising contacting the JAK kinase with an amount of a compound according to formula I effective to inhibit an activity of the JAK kinase or therapeutically acceptable salt thereof, wherein: ring A is phenyl; ring B is benzofuranyl; q is 0, 1, 2 or 3; p is 0; R is hydrogen or lower alkyl; X is selected from the group consisting of hydrogen, alkyl, substituted alkyl, hydroxy, alkoxy, substituted alkoxy, amino, substituted amino, carboxyl, carboxyl ester, cyano, halo, nitro, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkynyl, substituted cycloalkynyl; Y is a covalent bond; alk is a covalent bond; R each R R