Patent ID: 6034116
Filing Date: 2000-03-07
Classification: A61K,A61P

Abstract:
A mixture of a substituted benzimidazole of the formula ##STR23## in which R.sub.1, R.sub.2, R.sub.3 and R.sub.4 each, independently of one another, represent hydrogen, halogen, represent in each case optionally substituted alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, represent optionally substituted fused-on dioxyalkylene, but where at least one of the substituents R.sub.1, R.sub.2, R.sub.3 and R.sub.4 is neither hydrogen nor halogen,R.sub.5 represents hydrogen, represents alkyl which is substituted one or more times, identically or differently, by OH, CN, NH.sub.2, alkyl, cycloalkyl, alkenyl, alkinyl, alkoxy, halogenoalkoxy, alkylthio, halogenoalkylthio, alkenoxy, alkinoxy, aminocarbonyl, optionally substituted alkylcarbonyl, optionally substituted hetero-arylcarbonyl, optionally substituted alkoxycarbonyl (AlkO--CO--), optionally substituted alkoxycarbonyloxy (AlkOCOO--), aminosulphonyl (SO.sub.2 NH.sub.2), optionally substituted mono- or dialkylaminosulphonyl, alkylsulphonyl, alkenylsulphonyl, hetero-arylsulphonyl, or --SO.sub.2 NR.sub.8 R.sub.9, --CONR.sub.8 R.sub.9 or --P(O)(NR.sub.8 R.sub.9).sub.2, where R.sub.8 and R.sub.9 represent H or alkyl which is optionally substituted by one or more radicals, acylated amino (AlkCON(R.sub.7)-- or AlkOCON(R.sub.7)--), where R.sub.7 hydrogen, alkyl or cycloalkyl, or optionally substituted alkylsulphonylamino (AlkylSO.sub.2 NH--), or alkylsulphonyl-N-alkylamino (ArylSO.sub.2 NAlkyl--), optionally substituted arylsulphonylamino (ArylSO.sub.2,NH--) or arylsulphonyl-N-alkylamino (ArylSO.sub.2 NAlk--), optionally substituted dialkylamino,R.sub.6 represents fluoroalkyl, with a polyether antibiotic selected from the group consisting of maduramycin, lasalocid, monensin, narasin, and salinomycin or one or more synthetic coccidiostat selected from the group consisting of1(-(4-Amino-2-n-propyl-5-pyrimidinylmethyl)-2-picolinium chloride,1(-(4-Amino-2-n-propyl-5-pyrimidinylmethyl)-2-picolinium chloride+sulfaquinoxaline,1(-(4-Amino-2-n-propyl-5-pyrimidinylmethyl)-2-picolinium chloride+sulfaquinoxaline+ethopabate,4,4-Dinitrocarbanilide+2-hydroxy-4,6-dimethylpyrimidine,3,5-Dichloro-2,6-dimethyl-4-pyridinol,3,5-Dichloro-2,6-dimethyl-4-pyridinol+methyl 7-benzyloxy-6-butyl-1,4-dihydro-4-oxylquinoline-3-carboxylate,Ethyl 6-n-decyloxy-7-ethoxy-4-hydroxyquinoline-3-Carboxylate,9-(2-Chloro-6-fluorophenylmethyl)-9H-purin-6-amine,(.+-.)-2,6-Dichloro-alpha-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-t riazin-2(3H)-yl)-benzeneacetonitrile,1-[3-Methyl-4-(4'-trifluoromethylthiophenoxy)-phenyl]-3-methyl-1,3,5-triazi ne-2,4,6(1H,3H,5H)-trione,4,4-Dinitrocarbanilide+2-hydroxy-4,6-dimethylpyrimidine,7-Bromo-6-chloro-febrifugin, and3,5-Dinitro-o-toluamideas a composition for controlling parasitic protozoa.