Patent ID: 8637498
Filing Date: 2014-01-28
Classification: A61P,C07D

Abstract:
1. A compound of Formula (Ia) wherein Y is i) a C ii) a heteroaryl selected from the group consisting of thiazolyl, oxazolyl, pyridinyl, and pyrimidinyl, wherein Y is unsubstituted or substituted with one or two substituents each of which is independently selected from the group consisting of fluoro, chloro, C Z is selected from the group consisting of i) a C ii) a heteroaryl selected from the group consisting of benzoxazolyl, benzothiazolyl, benzothienyl, indazolyl, and indolyl, or iii) phenylmethyl-phenyl; wherein the phenyl of phenylmethyl is unsubstituted or substituted with one or two substituents each of which is independently selected from the group consisting of bromo, chloro, fluoro, iodo, C wherein the C provided that no more than one substituent of Z is phenyl and said phenyl is unsubsituted or substituted with one or two subsituents each of which is independently selected from the group consisting of trifluoromethyl, chloro, cyano, and fluoro; n is 1 or 2; and enantiomers, diastereomers, and pharmaceutically acceptable salts thereof.