Patent ID: 6583157
Filing Date: 2003-06-24
Classification: C07C,C07D

Abstract:
A compound having the formula (I): whereinAr1 is a member selected from the group consisting of substituted or unsubstituted 2-benzothiazolyl; X is selected from the group consisting of â€”Oâ€”, â€”C(O)â€”, â€”CH(R10)â€” and â€”N(R11)â€”; wherein R10 is a member selected from the group consisting of hydrogen, cyano and (C1-C4)alkyl; and R11 is a member selected from the group consisting of hydrogen and (C1-C8)alkyl; Y is â€”N(R12)â€”S(O)2â€”, wherein R12 is a member selected from the group consisting of hydrogen and (C1-C8)alkyl; R1 is a member selected from the group consisting of hydrogen, cyano, (C2-C8)heteroalkyl, halogen, (C1-C8)alkyl, (C1-C8)alkoxy, â€”C(O)R14, â€”CO2R14, â€”C(O)NR15R16, â€”S(O)pâ€”R14, â€”S(O)qâ€”NR15R16, â€”Oâ€”C(O)â€”R17 and â€”N(R14)â€”C(O)â€”R17; wherein R14 is a member selected from the group consisting of hydrogen, (C1-C8)alkyl, (C2-C8)heteroalkyl, aryl and aryl(C1-C4)alkyl; R15 and R16 are members independently selected from the group consisting of hydrogen, (C1-C8)alkyl, (C2-C8)heteroalkyl, aryl, and aryl(C1-C4)alkyl, or taken together with the nitrogen to which each is attached form a 5-, 6- or 7-membered ring; R17 is a member selected from the group consisting of (C1-C8)alkyl, (C2-C8)heteroalkyl, aryl and aryl(C1-C4)alkyl; the subscript p is an integer of from 0 to 3; and the subscript q is an integer of from 1 to 2; R2 is substituted or unsubstituted aryl; and R3 is a member selected from the group consisting of halogen and (C1-C8)alkoxy.