Patent ID: 7247637
Filing Date: 2007-07-24
Classification: A61K,A61P,C07D

Abstract:
1. A compound represented by formula (I): wherein X is hydrogen, halogen, trifluoromethyl, lower alkyl, unsubstituted or substituted phenyl, lower alkyl-thio, phenyl-lower alkyl-thio, lower alkyl-sulfonyl, or phenyl-lower alkyl-sulfonyl; Y is hydrogen, hydroxyl, mercapto, lower alkoxy, lower alkyl-thio, halogen, lower alkyl, unsubstituted or substituted mononuclear aryl, or —N(R R each R R wherein each R each o is, independently, an integer from 0 to 10; each p is an integer from 0 to 10; with the proviso that the sum of o and p in each contiguous chain is from 1 to 10; each x is, independently, O, NR wherein each R each Link is, independently, —O—, —(CH each CAP is, independently, —CR each Ar is, independently, phenyl, substituted phenyl, wherein the substituents of the substituted phenyl are 1–3 substituents independently selected from the group consisting of OH, OCH each R wherein when two R each R each R each R each R each Z is, independently, CHOH, C(═O), CHNR each R each R each R each Het is independently, —NR each g is, independently, an integer from 1 to 6; each m is, independently, an integer from 1 to 7; each n is, independently, an integer from 0 to 7; each Q is, independently, C—R each V is, independently, —(CH with the proviso that, when any two —CH or a pharmaceutically acceptable salt thereof; and inclusive of all enantiomers, diastereomers, and racemic mixtures thereof.