Patent ID: 7642354
Filing Date: 2010-01-05
Classification: A61P,C07D

Abstract:
1. A compound having a structure according to Formula I: or a pharmaceutically acceptable salt thereof, wherein A is substituted or unsubstituted pyridinyl, substituted or unsubstituted benzopyridinyl; B is substituted or unsubstituted pyridinyl, substituted or unsubstituted benzopyridinyl; W W Z Z Y is —NR s and t are independently integers from 1 to 4; R R R wherein if s is greater than one, then each R wherein if t is greater than one, then each R wherein two R wherein two R wherein substituents for the alkyl, heteroalkyl, cycloalkyl, heterocycloalkyl, are selected from the group consisting of —OR′, ═O, ═NR′, ═N—OR′, —NR′R″, —SR′, -halogen, —SiR′R″R′″, —OC(O)R′, —C(O)R′, —CO wherein substituents for the aryl and heteroaryl groups are selected from the group consisting of halogen, —OR′, —NR′R″, —SR′, -halogen, —SiR′R″R′″, —OC(O)R′, —C(O)R′, —CO wherein the heteroaryl is selected from the group consisting of 1 -pyrrolyl, 2-pyrrolyl, 3-pyrrolyl, 3-pyrazolyl, 2-imidazolyl, 4-imidazolyl, pyrazinyl, 2-oxazolyl, 4-oxazolyl, 2-phenyl-4-oxazolyl, 5-oxazolyl, 3-isoxazolyl, 4-isoxazolyl, 5-isoxazolyl, 2-thiazolyl, 4-thiazolyl, 5-thiazolyl, 2-furyl, 3-furyl, 2-thienyl, 3 -thienyl, 2-pyridinyl, 3-pyridinyl, 4-pyridinyl, 2-pyrimidyl, 4-pyrimidyl, 5-benzothiazolyl, purinyl, 2-benzimidazolyl, 5-indolyl, 1-isoquinolyl, 5-isoquinolyl, 2-quinoxalinyl, 5-quinoxalinyl, 3-quinolyl, and 6-quinolyl; and wherein the heterocycloalkyl is selected from the group consisting of 1-(1,2,5,6-tetrahydropyridyl), 1 -piperidinyl, 2-piperidinyl, 3-piperidinyl, 4-morpholinyl, 3 -morpholinyl, tetrahvdrofuran-2-yl, tetrahydrofuran-3-yl, tetrahydrothien-2-yl tetrahydrothien-3-yl, 1-piperazinyl, 2-piperazinyl, 1 -pyrrolidinyl and pyrrolidin-1-yl-2-one.