Patent ID: 8750979
Filing Date: 2014-06-10
Classification: A61B,A61N

Abstract:
1. An implantable medical device comprising: at least two implantable electrodes configured to communicate electric signals with a tissue; a memory configured to store a predetermined value representative of a β-dispersion frequency associated with cell membranes in said tissue; a signal generator configured to generate a first signal at a frequency in a first frequency window as a function of the stored predetermined value representative of the β-dispersion frequency, the frequency window extending from the stored predetermine value representative of the β-dispersion frequency to a frequency corresponding to about 90% of the stored value representative of said β-dispersion frequency, said first signal being communicated to said tissue via said at least two implantable electrodes; a signal measurer configured to measure a first resulting signal collected by said at least two implantable electrodes; a parameter determiner configured to determine, based on said first signal and said first resulting signal, a first impedance parameter representative of an impedance of said tissue; and a status monitor configured to monitor a permeability status of said cell membranes in said tissue based on said first impedance parameter.