Patent ID: 9052326
Filing Date: 2015-06-09
Classification: A61K,G01N

Abstract:
1. A method of treating a cardiovascular disease in a subject having a low level of mitochondrial inhibitory factor 1 in blood, comprising: measuring the level of mitochondrial inhibitory factor 1 in a blood sample obtained from a subject, comparing the level of mitochondrial inhibitory factor 1 measured in the blood sample obtained from said subject to a reference value administering to a subject, which has been identified as having a low level of mitochondrial inhibitory factor 1 as compared to the reference value, an agent that raises a level of high-density lipoprotein (HDL) in said subject, wherein said agent is selected from the group consisting of lipid-poor apoA-I, apoA-I associated with a phospholipid mixture, apoA-I mimetics and cholesteryl ester transfer protein (CETP) inhibitors, wherein said reference value is determined