Patent ID: 9121007
Filing Date: 2015-09-01
Classification: A61K,A61P,C12N

Abstract:
1. An in vitro method of suppressing the proliferation of cells of a bone-related cancer, comprising contacting said cells of a bone-related cancer with a plurality of placental stem cells for a time sufficient for said placental stem cells to suppress proliferation of said cells of a bone-related cancer, as compared to a plurality of said cells of a bone-related cancer not contacted with placental stem cells, wherein said placental stem cells are CD34 − , CD 10 + , CD 105 + and CD200 + as detectable by flow cytometry, and are not trophoblasts, cytotrophoblasts or bone marrow-derived mesenchymal stem cells, and wherein said cells of a bone-related cancer are multiple myeloma cells, chondrosarcoma cells, osteosarcoma cells, Ewing sarcoma cells, chordoma cells, cells of a malignant fibrous histiocytoma of bone, or cells of a fibrosarcoma of bone not prostate cancer cells.