Patent ID: 9107871
Filing Date: 2015-08-18
Classification: A61K,A61P,C12M

Abstract:
1. A method for obtaining the production of a fertilizable oocyte within a program of assisted reproduction techniques in a female human selected for controlled ovarian stimulation, consisting of: (a) allowing normal follicular growth and development to proceed in the absence of stimulation by an exogenous gonadotropin; (b) administering an amount of LHRH antagonist Cetrorelix in a dosage regimen that prevents a premature LH surge, beginning on menstruation cycle day 1 to 10; wherein follicular growth and development proceeds in the absence of a LH surge and a fertilizable oocyte is produced, ovulation occurs between day 9 and 20 of the menstruation cycle, wherein said amount of Cetrorelix is administered by a dosage regimen of from 0.25 to 0.5 mg/day for 3 to 10 days, wherein said amount of said Cetrorelix does not suppress endogenous FSH secretion, which is maintained at a natural level and individual estrogen development is not affected.