Patent ID: 6635636
Filing Date: 2003-10-21
Classification: C07D

Abstract:
A compound of the formula: wherein:a) X is â€”NK; b) R is â€”C1-4alkyl optionally substituted by one or more of heteroatoms selected from O, S, and N, â€”C3-6cycloalkyl optionally substituted by one or more of heteroatoms selected from O, S, and N, -aryl, arylalkyl, or heterocycle; c) Y is â€”H, â€”C1-4alkyl, or â€”C3-6cycloalkyl; d) Z is â€”C1-4alkyl, or â€”C3-6cycloalkyl; e) R1 is â€”H, â€”C1-4alkyl, halogen, â€”NO2, â€”OW, or â€”SW; f) R2 is â€”H, â€”C1-4alkyl, -halogen, â€”NO2, â€”OW, or â€”SW; g) R3 is â€”H, â€”C1-4alkyl, -halogen, â€”NO2, â€”OW, or â€”SW; h) R4 is â€”H, â€”C1-4alkyl, -halogen, â€”NO2, â€”OW, or â€”SW; i) R5 is â€”H, â€”C1-4alkyl, -halogen, â€”NO2, â€”OW, or â€”SW; j) K is â€”H, â€”C1-4alkyl, or â€”C3-6cycloalkyl; and k) W is â€”H, â€”CH3, or -aryl; or a pharmaceutically acceptable salt thereof.