Patent ID: 7280922
Filing Date: 2007-10-09
Classification: G16B

Abstract:
1. A method for determining a change of genotype between two samples from an individual, comprising: receiving a plurality of probe intensity values; calculating a first genotyping data value and a second genotyping data value using one or more of the probe intensity values associated with a first strand and one or more of the probe intensity values associated with a second strand; calculating a difference value using the first genotyping data value and the second genotyping data value; normalizing the difference value using a normalization value for the first strand and a normalization value for the second strand; and determining a change of genotype call, wherein the change of genotype call is true when the first genotyping data value correlates with a heterozygous genotype call and the second genotyping data value correlates with a homozygous genotype call and the normalized difference value is greater than a threshold value.