Patent ID: 8367097
Filing Date: 2013-02-05
Classification: A61K,A61P

Abstract:
1. A method for treating uveitis in a human subject, the method comprising administering to the human subject by intravitreal injection a volume of a liquid formulation comprising an effective amount of a therapeutic agent to treat uveitis in the human subject for at least two months, wherein the liquid formulation comprises the therapeutic agent, polyethylene glycol and ethanol, wherein the therapeutic agent is selected from the group consisting of rapamycin, and pharmaceutically acceptable salts thereof, wherein the liquid formulation is a liquid solution that forms a non-dispersed mass when injected into the vitreous, and wherein the therapeutic agent comprises between 0.5% to 6.0% of the total weight of the liquid formulation, and the polyethylene glycol comprises between 80% to 99% of the total weight of the liquid formulation.