Patent ID: 8647604
Filing Date: 2014-02-11
Classification: A61K,B82Y

Abstract:
1. An aqueous-soluble, lanthanide-rich nanoparticle composite, comprising: an inorganic, paramagnetic core consisting of at least one lanthanide ion selected from ions of Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, La, Lu, Y, and combinations thereof, and at least one anion selected from a halide, a phosphate, and a vanadate; at least one aqueous-soluble, organic ligand selected from citrate, biotin, amino acids, H at least one surface-modifying reagent that has been reacted with the at least one aqueous-soluble, organic ligand to form a surface-modifying reagent-aqueous soluble organic ligand reaction product.