Patent ID: 7057067
Filing Date: 2006-06-06
Classification: B01J,C07B,C07C,C07D

Abstract:
1. A process for producing a 2-halobenzoic acid represented by the following formula (I): {wherein X represents a chlorine atom, a bromine atom or an iodine atom; A represents —OH, —OM (in this formula, M represents an alkali metal atom) or —N(R (in this formula, R 1 , R 2 , R 3 and R 4 which may be the same or different represent a hydrogen atom or a C 1 –C 6 alkyl group, R 5 represents a C 1 –C 6 alkyl group, m represents an integer of 0 or 1, and k represents an integer of 1 or 2); a group represented by the following formula: (in this formula, R 8 , R 9 and R 10 which may be the same or different represent a hydrogen atom or a C 1 –C 6 alkyl group); or a group represented by the following formula: (in this formula, R 11 , R 12 , R 13 , R 14 , R 15 and R 16 which may be the same or different represent a hydrogen atom or a C 1 –C 6 alkyl group and I represents an integer of 1 or 2)); R which may be the same or different represents a hydrogen atom; a halogen atom; a cyano group; a nitro group; a C n represents an integer of 0 to 4; or alternatively (R)n may be linked to an adjacent carbon atom on the benzene ring to form a fused ring being a C characterized by reacting a benzoic acid represented by the following formula (II): (wherein A, R and n are as defined above), with a halogenating agent in the presence of a palladium catalyst.