Patent ID: 7622499
Filing Date: 2009-11-24
Classification: A61P,C07C,C07D

Abstract:
1. A compound having a substituted coumarylmethyl group connected to the nitrogen atom of the α-amino group of an L-threo-β-benzyloxylasparate or its benzene ring-substituted analog through a carbamate bond, represented by the following formula (2): wherein R 1 represents hydrogen atom, amino group, straight or branched lower aliphatic acylamino group optionally substituted at the acyl group portion, alicyclic acylamino group or aromatic acylamino group optionally having a substituent on the aromatic ring, and R 4 and R 5 each represent hydrogen atom, hydroxyl group, straight or branched lower alkyloxy group optionally substituted at the alkyl portion, amino group, straight or branched lower alkyl-substituted amino group, or a halogen atom.