Patent ID: 6608174
Filing Date: 2003-08-19
Classification: A61K,A61P,C07K

Abstract:
A radiolabeled peptide analog of vasoactive intestinal peptide comprising a receptor-binding peptide analog of vasoactive intestinal peptide (VIP) radiolabeled with a radionuclide wherein said receptor-binding peptide analog of vasoactive intestinal peptide is of the sequence:His-Ser-Asp-Xxx-Val-4-Cl-D-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Leu-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2 (SEQ ID NO:13) where Xxx is Aib (&agr;-amino isobutyric acid), Deg (&agr;,&agr;-di-ethylglycine) or Ac5c (1-aminocyclopentane carboxylic acid) or a salt thereof.