Patent ID: 7375112
Filing Date: 2008-05-20
Classification: A61K,A61P,C07D

Abstract:
1. A method of treating hypertriglyceridemia comprising administering a therapeutically effective amount for treating hypertriglyceridemia of a compound selected from the group consisting of pyridoxal, pyridoxal-5′-phosphate, pyridoxamine, a 3-acylated analogue of pyridoxal, a 3-acylated analogue of pyridoxal-4,5-aminal, a pharmaceutically acceptable salt thereof, and a mixture thereof to a patient in need thereof; a) wherein the 3-acylated analogue of pyridoxal comprises: wherein R b) wherein the 3-acylated analogue of pyridoxal-4,5-aminal comprises: wherein R R wherein R 3 and R 4 are each independently alkyl, alkenyl, cycloalkyl, aryl, or, when R 3 and R 4 are taken together to form a ring with the nitrogen atom, which may optionally be interrupted by a heteroatom, or a pharmaceutically acceptable acid addition salt thereof.