Patent ID: 9068227
Filing Date: 2015-06-30
Classification: C12Q,G01N

Abstract:
1. A composition comprising: (i) a polymerase reaction buffer and/or hybridization solution; and (ii) at least one isolated single stranded nucleic acid comprising at least 17 contiguous nucleotides of SEQ ID NO: 4 including the thymidine at position 171, or at least one isolated single stranded nucleic acid consisting of the sequence selected from the group consisting of SEQ ID NOS: 19, 20, 23, 24, 43, and 44; wherein the isolated nucleic acid is labeled with a detectable label selected from the group consisting of a fluorescent compound, a chemiluminescent (chromophore) compound, and an enzyme; and wherein the composition is used to detect a ARVD/C associated mutant TMEM43.