Patent ID: 6864267
Filing Date: 2005-03-08
Classification: A61K,C07D

Abstract:
1. A compound selected from the group consisting of: N-[(2R)-Hydroxy-3-[[2-cyano-5-[[5-ethylcarboxyl]-3-pyridyl]phenoxy]propyl]]-1,1-dimethyl-2-(5-chlorothienyl)ethylamine; N-[(2R)-Hydroxy-3-[[2-cyano-5-[[5-carboxyl]-3-pyridyl]phenoxy]propyl]]-1,1-dimethyl-2-(5-chlorothienyl)ethylamine; N-[(2R)-Hydroxy-3-[[2-cyano-5-[[5-ethylcarboxyl]-3-pyridyl]phenoxy]propyl]]-1,1-dimethyl-2-(indan-2-yl)ethylamine; N-[(2R)-Hydroxy-3-[[2-cyano-5-[[5-carboxyl]-3-pyridyl]phenoxy]propyl]]-1,1-dimethyl-2-(indan-2-yl)ethylamine; N-[(2R)-Hydroxy-3-[[2-cyano-5-[[5-ethylcarboxyl]-3-pyridyl]phenoxy]propyl]]-1,1-dimethyl-4-(methoxyphenyl)ethylamine; N-[(2R)-Hydroxy-3-[[2-cyano-5-[[5-carboxyl]-3-pyridyl]phenoxy]propyl]]-1,1-dimethyl-4-(methoxyphenyl)ethylamine; N-[(2R)-Hydroxy-3-[[2-cyano-5-[[3-ethylcarboxyl]-2-pyridyl]phenoxy]propyl]]-1,1- dimethyl-2-(5-chlorothienyl)ethylamine; N-[(2R)-Hydroxy-3-[[2-cyano-5-[[3-carboxyl]-2-pyridyl]phenoxy]propyl]]-1,1-dimethyl-2-(5-chlorothienyl)ethylamine; N-[(2R)-Hydroxy-3-[[2-cyano-5-[[3-ethylcarboxyl]-2-pyridyl]phenoxy]propyl]]-1,1-dimethyl-2-(indan-2-yl)ethylamine; N-[(2R)-Hydroxy-3-[[2-cyano-5-[[3-carboxyl]-2-pyridyl]phenoxy]propyl]]-1,1-dimethyl-2-(indan-2-yl)ethylamine; N-[(2R)-Hydroxy-3-[[2-cyano-5-[[3-ethylcarboxyl]-2-pyridyl]phenoxy]propyl]]-1,1-dimethyl-4-(methoxyphenyl)ethylamine; N-[(2R)-Hydroxy-3-[[2-cyano-5-[[3-carboxyl]-2-pyridyl]phenoxy]propyl]]-1,1-dimethyl-4-(methoxyphenyl)ethylamine; N-[(2R)-Hydroxy-3- [[2-cyano-4-[[4-ethylcarboxyl]phenyl]-3-pyridyloxy]propyl]]-1,1-dimethyl-2-(5-chlorothienyl)ethylamine; N-[(2R)-Hydroxy-3-[[2-cyano-4-[[4-carboxy]phenyl]-3-pyridyloxy]propyl]]-1,1-dimethyl-2-(5-chlorothienyl)ethylamine; N-[(2R)-Hydroxy-3-[[2-cyano-4-[[4-ethylcarboxyl]phenyl]-3-pyridyloxy]propyl]]-1,1-dimethyl-2-(indan-2-yl)ethylamine; N-[(2R)-Hydroxy-3-[[2-cyano-4-[[4-carboxyl]phenyl]-3-pyridyloxy]]-1,1-dimethyl-2-(indan-2-yl)ethylamine; N-[(2R)-Hydroxy-3-[[2-cyano-4-[[4-ethylcarboxyl]phenyl]-3-pyridyloxy]propyl]]-1,1-dimethyl-4-(methoxyphenyl)ethylamine; N-[(2R)-Hydroxy-3-[[2-cyano-4-[[4-carboxyl]phenyl]-3-pyridyloxy]propyl]]-1,1-dimethyl-4-(methoxyphenyl)ethylamine.