Patent ID: 6491953
Filing Date: 2002-12-10
Classification: A61K,Y10S

Abstract:
A composition comprising:(a) microparticles of an adsorbent polymer, said microparticles free of a monounsaturated monomer, and having a mean unit particle size of about 0.5 to about 80 microns and a bulk density of about 0.008 to about 0.1 gm/cc, and wherein the microparticles are prepared by a suspension polymerization process and are in the form of open spheres and sections of spheres; (b) an oil-soluble topically active compound, said active compound adsorbed onto said adsorbent polymer microparticles, wherein the active compound is present in a weight amount at least equal to and up to twenty times greater than the weight amount of the adsorbent polymer; and (c) a water-soluble release retardant, said release retardant coated and adsorbed onto said adsorbent polymer microparticles and said active compound.