Patent ID: 8211659
Filing Date: 2012-07-03
Classification: G01N

Abstract:
1. A method of detecting metastasis of cancer in a body fluid from a mammal, the method comprising the steps of: (a) providing the body fluid from the mammal; and (b) measuring secreted cellular apoptosis susceptibility (CAS/CSE1L) protein level or secreted CAS/CSE1L polypeptide level using an immunological binding assay in the body fluid to screen or diagnose the metastatic cancer, wherein the metastatic cancer is detected when the secreted CAS/CSE1L protein level or secreted CAS/CSE1L polypeptide level in the body fluid is increased relative to the secreted CAS/CSE1L protein level or secreted CAS/CSE1L polypeptide level in the body fluid of an individual without cancer or in the body fluid of a patient with non-metastatic cancer.