Patent ID: 7629350
Filing Date: 2009-12-08
Classification: A61P,C07D

Abstract:
1. The compound which is: 8-(2,4,6-trifluorophenyl)-4-(2,4-difluorophenyl)-2-(2-hydroxy-1-hydroxymethylethylamino)-8H-pyrido[2,3-d]pyrimidin-7-one; 4,8-Bis-(2,4-difluoro-phenyl)-2-(2-hydroxy-1-hydroxymethylethylamino)-8H-pyrido-[2,3-d]-pyrimidin-7-one; 8-(2,4,6-trifluorophenyl)-4-(2-fluorophenyl)-2-(2-hydroxy-1-hydroxymethylethylamino) -8H-pyrido[2,3-d]pyrimidin-7-one; 8-(2,4,6-trifluorophenyl)-4-(4-fluorophenyl)-2-(2-hydroxy-1-hydroxymethylethylamino) -8H-pyrido[2,3-d]pyrimidin-7-one; 4-(2-fluoro-phenyl)-8-(2,4-difluoro-phenyl)-2-((S)-2-hydroxy-1-methyl-ethylamino)-8H-pyrido-[2,3-d]-pyrimidin-7-one; 4-(2,4-Difluoro-phenyl)-8-(4-fluoro-phenyl)-2-((S)-2-hydroxy-1-methyl-ethylamino)-8H-pyrido-[2,3-d]-pyrimidin-7-one; 4,8-Bis-(2,4-difluoro-phenyl)-2-(2-hydroxy-1-methyl-ethylamino)-8H-pyrido-[2,3-d]-pyrimidin-7-one; 8-(2,4-Difluorophenyl)-4-(2-chloro-4-fluorophenyl)-2-(2-hydroxy-1-hydroxymethylethylamino)-8H-pyrido[2,3-d]pyrimidin-7-one; or 8-(2,3-difluorophenyl)-4-(2,4-difluorophenyl)-2-(2-hydroxy-1-hydroxymethyl-ethylamino)-8H-pyrido[2,3-d]pyrimidin-7- one; or a pharmaceutically acceptable salt thereof.