Patent ID: 9095591
Filing Date: 2015-08-04
Classification: A61K,A61P

Abstract:
1. A method for treating glaucoma in a subject in need thereof, comprising administering to eye tissue of said subject a therapeutically effective amount of a compound which is an antagonist of CXCR3 or an inhibitor of CXCR3 receptor expression, wherein said compound is the sole active agent for treating glaucoma in said subject, and wherein said compound is (N-[1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(pyridin-3-ylmethyl)acetamide); (N-[(1R)-1[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyridin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethoxy) phenyl]acetamide); or