Patent ID: 6352976
Filing Date: 2002-03-05
Classification: A61K,C07K

Abstract:
A compound of the formula wherein R1, R2 and R3 together are defined as follows:R1 is hydrogen; and R2 is selected from the group consisting of C1-C6 alkyl, â€”(CH2)4NH2, â€”(CH2)2â€”S(O)fâ€”CH3, and â€”(CH2)gâ€”Ar1â€²;wherein f is 0, 1, or 2; g is an integer from 1 to 2; Ar1â€² is a radical of â€ƒand R3 is selected from the group consisting of C1-C4 alkyl and â€”(CH2)pâ€”Ar3,wherein p is an integer from 1-2; Ar3 is â€ƒor wherein R1, R2 and R3 together are defined as follows:R1 is selected from the group consisting of hydrogen, C3-C6 alkyl, and â€”(CH2)dâ€”Ar1;wherein d is an integer from 1 to 2; Ar1 is a radical of â€ƒand R2 is selected from the group consisting of â€”(CH2)4NH2 and â€”(CH2)2â€”S(O)fâ€”CH3;wherein f is 0, 1, or 2; and R3 is selected from the group consisting of C1-C4 alkyl and â€”(CH2)pâ€”Ar3,wherein p is an integer from 1-2; Ar3 is and stereoisomers, pharmaceutically acceptable salts, and hydrates thereof.