Patent ID: 6344476
Filing Date: 2002-02-05
Classification: A61K,A61P,Y02A

Abstract:
A method for the treatment of a disease, other than cancer, mediated by p38, comprising administering a compound of Formula I whereinA is optionally substituted C6-12-aryl or C5-12-heteroaryl; R1 is H or C1-4-alkyl; R2 and R3 are each independently halogen, â€”COOR1, â€”CN, â€”CONR7R8, or â€”CH2NHR9; R5 is C3-5-alkyl; R6 is C1-6-alkyl; R7 is hydrogen; R8 is methyl; R9 is hydrogen, methyl or â€”COâ€”R10; and R10 is hydrogen or methyl optionally substituted by NR62 or COOR6.