Patent ID: 8114888
Filing Date: 2012-02-14
Classification: A61P,C07D

Abstract:
1. A compound or pharmaceutically acceptable salt thereof, wherein the compound is: 9-cyclopropyl-8-methoxy-7-(4-(piperidin-1-ylmethyl)phenyl)isothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione; 9-cyclopropyl-8-methoxy-7-(1,2,3,4-tetrahydroisoquinolin-6-yl)isothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione; 9-cyclopropyl-6-fluoro-7-(isoindolin-5-yl)-8-methoxyisothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione; 9-cyclopropyl-6-fluoro-8-methoxy-7-(1,2,3,4-tetrahydroisoquinolin-6-yl)isothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione; 9-cyclopropyl-8-methoxy-7-(2-methyl-1,2,3,4-tetrahydroisoquinolin-6-yl)isothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione; 9-cyclopropyl-6-fluoro-8-methoxy-7-(2-methyl-1,2,3,4-tetrahydroisoquinolin-6-yl)isothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione.