Patent ID: 6743917
Filing Date: 2004-06-01
Classification: C07D,C07F

Abstract:
A compound having the formula: wherein R1 and R2 are independently the same or different and are hydrogen, an alkyl group, a hydroxyalkyl group, a haloalkyl group, an aminoalkyl group, an alkylaminoalkyl group, a dialkylaminoalkyl group, an alkenyl group, an alkynyl group, an alkoxy group, an aryloxy group, an acyloxy group, â€”OC(O)ORd, wherein Rd is an alkyl group, a carbamoyloxy group, a halogen, a hydroxy group, a nitro group, a cyano group, an azido group, a formyl group, a hydrazino group, â€”C(O)Rf wherein Rf is an alkyl group, an alkoxy group, an amino group or a hydroxy group, an amino group, an alkylamino group, a dialkylamino group, â€”SRc, wherein Rc is hydrogen, â€”C(O)Rf, an alkyl group, or an aryl group; or R1 and R2 together form a group of the formula â€”O(CH2)nOâ€” wherein n represents the integer 1 or 2R3 is H, a halogen atom, a nitro group, an amino group, a hydroxy group, or a cyano group; or R2 and R3 together form a group of the formula â€”O(CH2)nOâ€” wherein n represents the integer 1 or 2; R4 is H, F, a C1-3 alkyl group, a C2-3 alkenyl group, a C2-3 alkynyl group, a trialkylsilyl group, or a C1-3 alkoxy group; wherein at least one of R1, R2, R3, and R4 is not H, a halogen, an alkyl group, an amino group or a nitro group; R5 is a C1-10 alkyl group, an allyl group, a benzyl group or a propargyl group; R6, R7 and R8 are independently a C1-10 alkyl group, a C2-10 alkenyl group, a C2-10 alkynyl group, an aryl group or a â€”(CH2)NR9 group, wherein N is an integer within the range of 1 through 10 and R9 is a hydroxy group, alkoxy group, an amino group, an alkylamino group, a dialkylamino group, a halogen atom, a cyano group or a nitro group; and R11 is an alkylene group or an alkenylene group; and pharmaceutically acceptable salts thereof.