Patent ID: 7598052
Filing Date: 2009-10-06
Classification: C12Q,G01N

Abstract:
1. A method for diagnosing papillary thyroid cancer in a subject, comprising: a) providing a thyroid tissue sample from a subject suspected of having papillary thyroid cancer; b)detecting an increased the level of expression of claudin 1 mRNA or polypeptide in said sample; c) comparing said level of expression of said claudin 1 mRNA or polypeptide in said sample with a level of expression of claudin 1 mRNA or polypeptide in a non-cancerous thyroid sample; and d) diagnosing papillary carcinoma thyroid cancer in said subject when an increased level of expression of said claudin 1 relative to the level of expression in non-cancerous thyroid samples is present in said sample.