Patent ID: 7326803
Filing Date: 2008-02-05
Classification: A61K,A61P,A61Q,C07C

Abstract:
1. A bicyclic compound having the structural formula (I): in which R 1 is a radical of formulae (a) to (c) below: wherein R 7 and R 8 are as defined below; each of the radicals R 2 and R 3 , which may be identical or different, is a hydrogen atom or an alkyl radical having from 1 to 6 carbon atoms; X is an Se atom, —CHOH, —CH 2 or —C═O; Q is an oxygen atom, a sulfur atom, CH 2 , —NH or —NR 9 —, wherein R 9 is as defined below; R 4 and R 5 , which may be identical or different, are each a hydrogen atom, an alkyl radical having from 1 to 6 carbon atoms, or together form an oxo radical; R 6 is a phenyl radical or a naphthyl radical, R 6 being optionally substituted with one or more radicals selected from among an alkyl radical having from 1 to 6 carbon atoms, an —OR 10 radical, a halogen atom, —CF 3 , —NH 2 and a nitrogen atom mono- or disubstituted with an alkyl radical having from 1 to 6 carbon atoms, wherein R 10 is as defined below; R 7 is a radical —COR 11 , wherein R 11 is as defined below; R 8 is a radical: wherein R 12 , R 13 and R 14 are as defined below; R 9 is an alkyl radical having from 1 to 6 carbon atoms; R 10 is a hydrogen atom or an alkyl radical having from 1 to 6 carbon atoms; R 11 is a radical —OR 15 or a radical —NR 15 R 16 , wherein R 15 and R 16 are as defined below; R 12 and R 13 , which may be identical or different, are each a hydrogen atom, a halogen atom, an alkyl radical having from 1 to 6 carbon atoms or a radical —OR 17 , wherein R 17 is as defined below; R 14 is a radical —COR 18 , wherein R 18 is as defined below; R 15 , R 16 and R 17 , which may be identical or different, are each a hydrogen atom or an alkyl radical having from 1 to 6 carbon atoms; R 18 is a radical —OR 19 , or a radical —NR 19 R 20 , wherein R 19 and R 20 are as defined below; R 19 is a hydrogen atom or an alkyl radical having from 1 to 6 carbon atoms; R 20 is a hydrogen atom, an alkyl radical having from 1 to 6 carbon atoms, or —OH, or a salt, isomer or mixture thereof.