Patent ID: 8765784
Filing Date: 2014-07-01
Classification: A61P,C07D,C07F

Abstract:
1. A compound according to Formula I wherein: Y is H, C R wherein groups (1) to (7) above are optionally substituted with 1 to 3 R each R ring A is selected from aryl, heteroaryl and heterocycle, wherein said heterocycle is fused to an aryl group or a heteroaryl group, and wherein said aryl, heteroaryl and heterocycle are optionally substituted with one or more R each R each X is independently selected from the group consisting of: H, C each k is independently 0, 1 or 2; each R is independently selected from the group consisting of: H and C each R each R aryl at each occurrence is independently selected from the group consisting of: phenyl, naphthyl, anthryl and phenanthryl; heteroaryl at each occurrence independently means a 5-membered monocyclic aromatic selected from the group consisting of isoxazolyl, isothiazolyl, pyrazolyl, oxazolyl, oxadiazolyl, thiadiazolyl, thiazolyl, imidazolyl, triazolyl, tetrazolyl, furanyl, triazinyl and thienyl, a 6-membered monocyclic aromatic or 9- or 10-membered bicyclic aromatic, wherein at least one atom in the aromatic is selected from N(R), O and S, the sulfur optionally oxidized to sulfone or sulfoxide, and the remaining atoms are selected from C, N(R), O and S, the sulfur optionally oxidized to sulfone or sulfoxide; heterocycle at each occurrence independently means a 4- to 7-membered monocyclic non-aromatic ring, an 8- to 11-membered bi-cyclic non-aromatic ring or a 12- to 20-membered tri-cyclic, non-aromatic ring, each optionally substituted with 1 to 2 oxo groups, wherein at least one atom is selected from N(R), O and S, the sulfur optionally oxidized to sulfone or sulfoxide, and the remaining atoms are selected from C, N(R), O and S, the sulfur optionally oxidized to sulfone or sulfoxide; or a pharmaceutically acceptable salt thereof.