Patent ID: 6743593
Filing Date: 2004-06-01
Classification: C07K,C12N,G01N

Abstract:
An immunoassay method for detecting infection in a human by human papillomavirus 16, said method comprising the steps of:reacting a sample of body fluid or tissue likely to contain serum antibodies raised against a polypeptide which includes amino acids 124 through 142 of the Eb2 early coding region of human papillomavirus 16 with a peptide according to SEQ ID NO.: 1, wherein carboxymethylcysteine is substituted for one or more cysteine residues in said peptide; forming a complex of said peptide and sample serum antibodies, wherein the formation of said antibody-peptide complex confirms the presence of serum antibodies to human papilloniavirus 16; and detecting said antibody-peptide complex.