Patent ID: 8503833
Filing Date: 2013-08-06
Classification: G01N,G02B,Y10S

Abstract:
1. A sensor for studying cell behaviour, the sensor comprising: a substrate; a waveguide grating structure on the substrate with the waveguide grating structure comprising a plurality of waveguide grating structure units or sensor locations; wherein at least one of said waveguide grating structure units or sensor locations comprises at least one sensing pad with a modified surface of the waveguide grating structure; the sensor further comprising: a chemofunctional layer in physical contact with said modified surface, the chemofunctional layer comprising at least one living cell, the chemofunctional layer covering at least partially said at least one waveguide grating structure unit or sensor location; wherein the at least one living cell is a living human cell or a living animal cell or a living plant cell; and a liquid sample in physical contact with the chemofunctional layer, the chemofunctional layer being thereby in physical contact with the modified surface and with the sample; wherein the waveguide grating structure has waveguiding properties and comprises at least one grating, and the waveguide grating structure emits at least one light field when an incident light field at least partially illuminates the waveguide grating structure, thereby being capable of producing a signal indicative of a reaction or a behaviour of the at least one living cell due to a contact with the sample.