Patent ID: 8202845
Filing Date: 2012-06-19
Classification: A01K,A61K,A61P,C12N,G01N

Abstract:
1. A method for the treatment of autosomal recessive retinitis pigmentosa or congenital stationary night blindness comprising: administering to a subject a therapeutically effective amount of a composition comprising a dsRNA between 21 and 23 nucleotides in length and a carrier, said dsRNA having a nucleotide sequence corresponding to mRNA of a target gene expressed in the eye; said administering of the composition occurring outside the blood-retina barrier, said composition inhibiting the target gene by RNA interference inside the eye, thereby treating autosomal recessive retinitis pigmentosa or congenital stationary night blindness, and wherein said target gene is SEQ ID NO:1 or SEQ ID NO:3.