Patent ID: 6228350
Filing Date: 2001-05-08
Classification: A61K,A61P,A61Q

Abstract:
A method of depigmenting or bleaching human skin, body hair or head hair or a combination thereof, comprising applying to human skin, body hair or head hair or a combination thereof at least one compound having the formula (I): ##STR2##wherein:R is a group selected from the group consisting ofhydrogen;linear, branched or cyclic, saturated or unsaturated C.sub.1 -C.sub.24 alkyl, which is optionally hydroxylated with one or more hydroxyl groups;aryl, which is optionally substituted with one or more groups selected from the group consisting of --OH, NH.sub.2, --COOH, --NO.sub.2, --OR.sub.5, wherein R.sub.5 is C.sub.1 -C.sub.24 alkyl, --COOR.sub.6, wherein R.sub.6 is C.sub.1 -C.sub.24 alkyl, and --NR.sub.7 R.sub.8, wherein R.sub.7 is H or C.sub.1 -C.sub.24 alkyl, and R.sub.8 is H or C.sub.1 -C.sub.24 alkyl; and--COR.sub.9, wherein R.sub.9 is a linear, branched or cyclic, saturated or unsaturated C.sub.1 -C.sub.24 alkyl, which is optionally hydroxylated with one or more hydroxyl groups; or aryl, which is optionally substituted with one or more groups selected from the group consisting of --OH, --NH.sub.2, --COOH, --NO.sub.2, --OR.sub.5, --COOR.sub.6, and --NR.sub.7 R.sub.8, wherein R.sub.5, R.sub.6, R.sub.7 and R.sub.8 are as defined above;R.sub.1 and R.sub.2, which are identical or different, each individually represent a group selected from the group consisting ofhydrogen;linear, branched or cyclic, saturated or unsaturated C.sub.1 -C.sub.24 alkyl, which is optionally hydroxylated with one or more hydroxyl groups;aryl, which is optionally substituted with one or more groups selected from the group consisting of --OH, --NH.sub.2, --COOH, --NO.sub.2, --OR.sub.5, --COOR.sub.6, and --NR.sub.7 R.sub.8, wherein R.sub.5, R.sub.6, R.sub.7 and R.sub.8 are as defined above;a group selected from the group consisting of --OH, --OQ.sub.1, --COQ.sub.2, --COOQ.sub.3, --NQ.sub.4 Q.sub.5, --CONQ.sub.6 Q.sub.7, --SQ.sub.8, --CH.sub.2 OQ.sub.9, wherein Q.sub.1, Q.sub.2, Q.sub.3, Q.sub.4, Q.sub.5, Q.sub.6, Q.sub.7, Q.sub.8 and Q.sub.9, which are identical or different, are selected from the group consisting of hydrogen, linear, branched cyclic, saturated, and unsaturated C.sub.1 -C.sub.24 alkyl groups, optionally substituted with one or more hydroxyl groups, aryl groups which are optionally substituted with one or more groups selected from the group consisting of --OH, --NH.sub.2, --COOH, --NO.sub.2, --OR.sub.5, --COOR.sub.6, and --NR.sub.7 R.sub.8, wherein R.sub.5, R.sub.6, R.sub.7 and R.sub.8 are as defined above; andamino acid residues and cyclic or non-cyclic carbohydrate residues; andR.sub.3 is a group selected from the group consisting ofhydrogen,linear, branched or cyclic, saturated or unsaturated C.sub.1 -C.sub.24 alkyl, which is optionally hydroxylated with one or more hydroxyl groups, andaryl, which is optionally substituted with one or more groups selected from the group consisting of --OH, --NH.sub.2, --COOH, --NO.sub.2, --OR.sub.5, --COOR.sub.6, and --NR.sub.7 R.sub.8, wherein R.sub.5, R.sub.6, R.sub.7 and R.sub.8 are as defined above.