Patent ID: 7601706
Filing Date: 2009-10-13
Classification: A61K,C07C,C07D,C07K

Abstract:
1. A compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein: R X is Q G is —O—, —C(O)O— or —NH—; Q wherein I is —[NR J is —[NR K is —[NR T is —[C(O)—(CR U is —[C(O)—(CR V is —[C(O)—(CR R R R a, b, c, d, e, f, g, h, m, n, o and p are independently 0 or 1, wherein at least one of a and b is 1; at least one of c and d is 1; at least one of e and f is 1; at least one of g and h is 1; at least one of m and n is 1; at least one of o and p is 1; i, j, k, t, u and v are independently 0 or 1; R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R D is a GABA analog moiety having the following formula: wherein R R R R R R R R Z is a substituted alkyl group containing a moiety which is negatively charged at physiological pH, which moiety is selected from the group consisting of —COOH, —SO