Patent ID: 6649759
Filing Date: 2003-11-18
Classification: C07D

Abstract:
A compound of the formula: wherein X is R1 is phenyl, thienyl or pyridyl each optionally substituted with one to three substituents selected from halogen, â€”OCF3, NO2, CN, hydroxy, alkylalkoxy, COOH, C1-C6alkyl, C1-C6hydroxyalkyl, C1-C6 aminoalkyl, aryl, heteroaryl, alkoxy, acyloxy, â€ƒNR7R8, C1-C4alkylthio, mono-, di-, or trihaloalkyl, or wherein R is phenyl, C1-C6alkyl, hydrogen, OH, or alkoxy; R2 is hydrogen or C1-C6alkyl; R3 and R4 are independently hydrogen, hydroxyl, â€”N(C1-C3alkyl)2, C1-C6alkyl, nitro, cyano, or alkylalkoxy, or aryloxy; Y is hydrogen, C1-C6alkyl, or pyridyl; n is 1 to 3; m is 1 to 3; and R7 and R8 are C1-C6 alkyl; with the proviso that when n is 2. Y is hydrogen or C1-C6alkyl; and R3 and R4 are both hydrogen, then R1 is not phenyl.