Patent ID: 6462022
Filing Date: 2002-10-08
Classification: A61K,A61P

Abstract:
A solid composition comprising between 1% (w/w) and 50% (w/w) lisinopril (1-(N2-[(S)-1-carboxy-3-phenylpropyl]-L-lysyl)-L-proline) or lisinopril dihydrate in combination with an excipient in an amount sufficient to make a total composition of 100%, which excipient comprises dibasic calcium phosphate dihydrate (DCPD) in an amount that is at least 30% (w/w) of the total composition, said DCPD having a specific surface area prior to any tabletting of the composition of less than 0.9 m2gâˆ’1, and one or more additional ingredients that are fillers, binders, disintegrants, or lubricants or glidants.