Patent ID: 8652788
Filing Date: 2014-02-18
Classification: C07D,G01N

Abstract:
1. An immunoassay for detecting cardiac myocyte damage in a subject from a test sample, the immunoassay comprising the steps of: a) contacting a test sample from a subject suspected of having cardiac myocyte damage with n antibodies (A b) contacting said mixture comprising n′ (n-antibody:antigen) immuno-complexes with n″ antibodies (B c) measuring an optical, electrical, or change-of-state signal of at least two antibody:antigen measurable assemblies of the n′ ((n+n′) antibody:antigen) measurable assemblies ((A d) detecting cardiac myocyte damage by determining whether the measurement in step (c) exceeds a predetermined level, wherein each antibody A a n binds to at least one epitope on a cardiac myocyte antigen a n′ that is different than any of the epitopes to which the antibodies B a n″ bind.