Patent ID: 7459473
Filing Date: 2008-12-02
Classification: A61K,A61P,A61Q,C07D

Abstract:
1. A method of stimulating neuronal regeneration and growth in a mammal having peripheral neuropathies caused by physical injury or disease state, physical damage to the brain, physical damage to the spinal cord, stroke associated with brain damage, or neurological disorders relating to neurodegeneration, comprising: administering to the animal an effective amount of a compound to stimulate growth of damaged peripheral nerves or to promote neuronal regeneration, where the compound has the formula (I): where n is 1; R D is selected from the group consisting of a bond, C R wherein said alkyl, alkenyl, alkylene, alkenylene, alkynylene, aryl, heteroaryl, carbocycle, heterocycle, or R 2 is optionally substituted with one or more substituents selected from R 3 , where R or a pharmaceutically acceptable salt thereof.