Patent ID: 8163776
Filing Date: 2012-04-24
Classification: A61K,A61P

Abstract:
1. A method for modulating an immune response comprising: identifying an individual suffering from an ailment selected from the group consisting of: renal failure in systemic lupus erythmatosus, bacterial endocarditis, mycosis and fungal infection; and administering to the individual an effective amount of a thione-forming disulfide having the general formula R-S-S-R, wherein the R group comprises an unsubstituted or substituted pyridinyl group thereby modulating the immune response and treating the ailment; wherein the thione-forming disulfide is selected from the group consisting of: 6,6′-dithiodinicotinic acid (CPDS), 6,6′-dithiodinicotinic acid diethyl ester, and 2,2′-dithiobis-isonicotinic acid.