Patent ID: 6231608
Filing Date: 2001-05-15
Classification: A61F,A61L

Abstract:
A method of preparing a xenograft formed of a soft or bone tissue for implantation into a human, which comprisesa. removing at least a portion of the soft or bone tissue from a non-human animal to provide a xenograft;b. washing the xenograft in water and alcohol;c. subjecting the xenograft to a cellular disruption treatment;d. exposing the xenograft to an aldehyde in an amount ranging from about 0.01% to about 0.10%; ande. digesting the xenograft with a glycosidase to remove substantially a plurality of first surface carbohydrate moieties from the xenograft whereby the xenograft is substantially non-immunogenic and has substantially the same mechanical properties as the native soft or bone tissue.