Patent ID: 7282494
Filing Date: 2007-10-16
Classification: A61P,C07D

Abstract:
1. A diazacycloalkane compound selected from the group consisting of: 5-(1-heptynyl)-3-pyridyl-homopiperazine; 5-(1-hexynyl)-3-pyridyl-homopiperazine; 5-(1-pentynyl)-3-pyridyl-homopiperazine; 5-(1-butynyl)-3-pyridyl-homopiperazine; 5-(1-propynyl)-3-pyridyl-homopiperazine; 5,6-dichloro-3-pyridyl-homopiperazine; 6-fluoro-3-pyridyl-homopiperazine; 6-iodo-3-pyridyl-homopiperazine; 5-chloro-6-fluoro-3-pyridyl-homopiperazine; 5-chloro-6-iodo-3-pyridyl-homopiperazine; 5-bromo-6-fluoro-3-pyridyl-homopiperazine; 5-bromo-6-iodo-3-pyridyl-homopiperazine; 6-fluoro-pyridazine-homopiperazine; 6-iodopyridazine-homopiperazine; 5-(trans-hex-2-en-1-yl-oxy)-3-pyridyl-homopiperazine; 5-ethoxy-3-pyridyl-4-(prop-2-en-1-yl)-homopiperazine; 1-(5-(cyclobutylmethoxy)-3-pyridyl)-homopiperazine; 1-(5-(hex-2-en-oxy)-3-pyridyl)-homopiperazine; 1-(5-(2-methyl-1-prop-1-en-oxy)-3-pyridyl)-homopiperazine; 1,4-Bis-[5-ethoxy-3-pyridyl]-homopiperazine; 1,4-Bis-[5-(1-propyl-1-en-oxy)-3-pyridyl]-homopiperazine; 1-(5-Iodo-3-pyridyl)-homopiperazine; 1,4-Bis-[5-(vinyl-oxy)-3-pyridyl]-homopiperazine; 1-[5-Phenyl-2-eth-1-yl-3-pyridyl]-homopiperazine; 1-[5-Ethyl-3-pyridyl]-homopiperazine; 1-[3-(4-Chloro-1,2,5-thiadiazolyl)]-homopiperazine; 1-(5-Bromo-3-pyridyl)-homopiperazine; 1-(6-Amino-3-pyridyl)-homopiperazine; 1-(6-Nitro-3-pyridyl)-homopiperazine; 1-[3-(1,2,5-thiadiazolyl)]-homopiperazine; 1-(6-Fluoro-5-ethynyl-3-pyridyl)-homopiperazine; 1-(6-Chloro-5-ethynyl-3-pyridyl)-homopiperazine; 1-(6-Bromo-5-ethynyl-3-pyridyl)-homopiperazine; 1-(6-Iodo-5-ethynyl-3-pyridyl)-homopiperazine; 1-(6-Fluoro-5-propyn-1-yl-3-pyridyl)-homopiperazine; 1-(6-Chloro-5-propyn-1-yl-3-pyridyl)-homopiperazine; 1-(6-Bromo-5-propyn-1-yl-3-pyridyl)-homopiperazine; 1-(6-Iodo-5-propyn-1-yl-3-pyridyl)-homopiperazine; 1-(6-Fluoro-5-butyn-1-yl-3-pyridyl)-homopiperazine; 1-(6-Chloro-5-butyn-1-yl-3-pyridyl)-homopiperazine; 1-(6-Bromo-5-butyn-1-yl-3-pyridyl)-homopiperazine; 1-(6-Iodo-5-butyn-1-yl-3-pyridyl)-homopiperazine; 1-(6-Fluoro-5-pentyn-1-yl-3-pyridyl)-homopiperazine; 1-(6-Chloro-5-pentyn-1-yl-3-pyridyl)-homopiperazine; 1-(6-Bromo-5-pentyn-1-yl-3-pyridyl)-homopiperazine; 1-(6-Iodo-5-pentyn-1-yl-3-pyridyl)-homopiperazine; 1-(6-Fluoro-5-ethenyl-3-pyridyl)-homopiperazine; 1-(6-Chloro-5-ethenyl-3-pyridyl)-homopiperazine; 1-(6-Bromo-5-ethenyl-3-pyridyl)-homopiperazine; 1-(6-Iodo-5-ethenyl-3-pyridyl)-homopiperazine; 1-(6-Fluoro-5-propen-1-yl-3-pyridyl)-homopiperazine; 1-(6-Chloro-5-propen-1-yl-3-pyridyl)-homopiperazine; 1-(6-Bromo-5-propen-1-yl-3-pyridyl)-homopiperazine; 1-(6-Iodo-5-propen-1-yl-3-pyridyl)-homopiperazine; 1-(6-Fluoro-5-buten-1-yl-3-pyridyl)-homopiperazine; 1-(6-Chloro-5-buten-1-yl-3-pyridyl)-homopiperazine; 1-(6-Iodo-5-buten-1-yl-3-pyridyl)-homopiperazine; 1-(6-Fluoro-5-penten-1-yl-3-pyridyl-homopiperazine; 1-(6-Chloro-5-penten-1-yl-3-pyridyl)-homopiperazine; 1-(6-Bromo-5-penten-1-yl-3-pyridyl)-homopiperazine; 1-(6-Iodo-5-penten-1-yl-3-pyridyl)-homopiperazine; 1-(6-Fluoro-5-ethyl-3-pyridyl)-homopiperazine; 1-(6-Chloro-5-ethyl-3-pyridyl)-homopiperazine; 1-(6-Bromo-5-ethyl-3-pyridyl)-homopiperazine; 1-(6-Iodo-5-ethyl-3-pyridyl)-homopiperazine; 1-(6-Fluoro-5-prop-1-yl-3-pyridyl)-homopiperazine; 1-(6-Chloro-5-prop-1-yl-3-pyridyl)-homopiperazine; 1-(6-Bromo-5-prop-1-yl-3-pyridyl)-homopiperazine; 1-(6-Iodo-5-prop-1-yl-3-pyridyl)-homopiperazine; 1-(6-Fluoro-5-but-1-yl-3-pyridyl)-homopiperazine; 1-(6-Chloro-5-but-1-yl-3-pyridyl)-homopiperazine; 1-(6-Bromo-5-but-1-yl-3-pyridyl)-homopiperazine; 1-(6-Iodo-5-but-1-yl-3-pyridyl)-homopiperazine; 1-(6-Fluoro-5-pent-1-yl-3-pyridyl)-homopiperazine; 1-(6-Chloro-5-pent-1-yl-3-pyridyl)-homopiperazine; 1-(6-Bromo-5-pent-1-yl-3-pyridyl)-homopiperazine; 1-(6-Iodo-5-pent-1-yl-3-pyridyl)-homopiperazine; 1-(6-Bromo-5-methoxy-3-pyridyl)-homopiperazine; 1-(6-Chloro-5-methoxy-3-pyridyl)-homopiperazine; 1-(6-Fluoro-5-methoxy-3-pyridyl)-homopiperazine; 1-(6-Iodo-5-methoxy-3-pyridyl)-homopiperazine; 1-(6-Chloro-5-ethoxy-3-pyridyl)-homopiperazine; 1-(6-Fluoro-5-ethoxy-3-pyridyl)-homopiperazine; 1-(6-Iodo-5-ethoxy-3-pyridyl)-homopiperazine; 1-(6-Bromo-5-propyloxy-3-pyridyl)-homopiperazine; 1-(6-Chloro-5-propyloxy-3-pyridyl)-homopiperazine; 1-(6-Fluoro-5-propyloxy-3-pyridyl)-homopiperazine; 1-(6-Iodo-5-propyloxy-3-pyridyl)-homopiperazine; 1-(6-Bromo-5-vinyloxy-3-pyridyl)-homopiperazine; 1-(6-Chloro-5-vinyloxy-3-pyridyl)-homopiperazine; 1-(6-Fluoro-5-vinyloxy-3-pyridyl)-homopiperazine; 1-(6-Iodo-5-vinyloxy-3-pyridyl)-homopiperazine; 1-(5-Ethenyl-3-pyridyl)-homopiperazine; 1-(5-Propen-1-yl-3-pyridyl)-homopiperazine; 1-(5-buten-1-yl-3-pyridyl)-homopiperazine; 1-(5-Penten-1-yl-3-pyridyl)-homopiperazine; 1-(5-Prop-1-yl-3-pyridyl)-homopiperazine; 1-(5-But-1-yl-3-pyridyl)-homopiperazine; and 1-(5-Pent-1-yl-3-pyridyl)-homopiperazine; or an enantiomer or any mixture of its enantiomers or a pharmaceutically acceptable salt thereof.