Patent ID: 7582771
Filing Date: 2009-09-01
Classification: C07D

Abstract:
1. A process for preparing a compound of formula (IV): in purified form, the process comprising converting a compound of formula (III): to the compound of formula (IV) by: using an alkali solution to remove the Y from the ester group in the compound of formula (III), thereby forming a carboxylic acid intermediate; purifying the carboxylic acid intermediate by slurrying the carboxylic acid intermediate in an organic solvent; using an alkali solution to hydrolyze the N-acetyl amide bond in the purified carboxylic acid intermediate, thereby forming an amino acid intermediate; and then, reacting the amino acid intermediate with R-A-(CH wherein: n represents an integer from 0 to 4; A is a chemical bond, —S—, —O—, —S(O)—, —S(O) R is a moiety selected from the group consisting of C X represents O or CH Y represents C Z is selected from the group consisting of H, halogen, —CN, —CHO, —CF