Patent ID: 6476076
Filing Date: 2002-11-05
Classification: A61P,C07C

Abstract:
A compound represented by the following formula (I): wherein,X is an oxygen or sulfur atom; A is â€”NHCH2â€” or â€”CH2â€”; R1 is a substituted or unsubstituted C1-4alkaryl group, or the group of the formula: R4COâ€” wherein R4 is an alkyl group having 1 to 18 carbon atoms, an alkenyl group having 2 to 18 carbon atoms, or a substituted or unsubstituted aryl group having 6 to 10 carbon atoms; R2 is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, an alkoxy group having 1 to 6 carbon atoms, a haloalkyl group having 1 to 6 carbon atoms or a halogen atom; R3 is a hydrogen atom, an alkyl grouip having 1 to 4 carbon atoms, an aminoalkyl, a diacid monoester, &agr;-alkyl acid; n is an integer of 1 to 2; and the asterisk mark * indicates a chiral carbon atom, and its pharmaceutically accepatable salts.