Patent ID: 9107858
Filing Date: 2015-08-18
Classification: A61K,A61P,C07K

Abstract:
1. A vaccine delivery system comprising: a carbon nanoparticle that is preferentially endocytosed by dendritic cells as compared to macrophages; and an antigenic protein or peptide conjugated to the nanoparticle, wherein the carbon nanoparticle is spherical and has a diameter of about 30 nm to about 70 nm, and wherein the carbon nanoparticle comprises iron, wherein the iron concentration of the nanoparticle is from 0.5% to 2.0%; wherein the antigenic protein or peptide induces an immune response comprising the production of antibodies specific for the antigenic protein or peptide; and wherein the nanoparticle is conjugated to an antibody capable of binding specifically to molecules on the surface of dendritic cells.