Patent ID: 6369089
Filing Date: 2002-04-09
Classification: A61P,C07D

Abstract:
A compound represented by the general formula I. whereinm is an integer of from 1 to 3; n is 0 or an integer of from 1 to 4; R is selected from the group consisting of CO2H, CO2 R6, CH2OH, CH2O R6 P(O)(OH)2, â€ƒand CONR3R4; R1 and R2 are independently selected from the group consisting of H, R6, C2-C6 alkenyl, C1-C6 alkynyl, C3-C7 cycloalkyl, C4-C12 alkylcycloalkyl, C6-C10 aryl and C7-C12 alkyl aryl radicals, wherein one or more of the hydrogen or carbon atoms in said radicals is replaced with a halogen; R3 and R4 are selected from the group consisting of H and R6; and X is selected from the group consisting of H, R6, hydroxy, N(R6)2, CON(R6)2, SR6, halogen, COOR6, NO2, CN and OR6, wherein R6 is C1-C6 alkyl; Y is O or S; Z is N or CH or a pharmaceutically acceptable salt thereof.