Patent ID: 7056909
Filing Date: 2006-06-06
Classification: A61K,A61P,C07D

Abstract:
1. A compound of the Formula (I) or a pharmaceutically acceptable salt thereof, wherein: X is wherein each non-aromatic ring carbon atom is unsubstituted or independently substituted with one or two R 1 substituents and each aromatic ring carbon atom is unsubstituted or independently substituted with one R 1 substituent selected from the group consisting of C or two R R R R and mono, di, and tri-substituted aryl wherein aryl is as defined above and the substituents are independently hydroxy, hydroxy-C 1-6 alkyl, halogen, C 1-8 alkyl, C 3-8 cycloalkyl, aryl, aryl C 1-3 alkyl, amino, amino C 1-6 alkyl, C 1-3 acylamino, C 1-3 acylamino-C 1-6 alkyl, C 1-6 alkylamino, di(C 1-6 )alkylamino, C 1-6 alkylamino-C 1-6 alkyl, di(C 1-6 )alkylamino-C 1-6 alkyl, C 1-4 alkoxy, C 1-4 alkylthio, C 1-4 alkylsulfinyl, C 1-4 alkylsulfonyl, C 1-4 alkoxy-C 1-6 alkyl, hydroxycarbonyl, hydroxycarbonyl-C 1-6 alkyl, C 1-5 alkoxycarbonyl, C 1-3 alkoxycarbonyl-C 1-6 alkyl, C 1-5 alkylcarbonyloxy, cyano, tnifluoromethyl, 1,1,1-trifluoroethyl, trifluoromethoxy, trifluoroethoxy, or nitro; or two adjacent substituents together with the carbon atoms to which they are attached join to form a five- or six-membered saturated or unsaturated ring containing 1 or 2 heteroatoms selected from the group consisting of N, O, and S, whose ring carbon atoms may be substituted with oxo or C 1-3 alkyl; and R