Patent ID: 6242187
Filing Date: 2001-06-05
Classification: C12N,C12Q,G01N

Abstract:
A method for determining susceptibility for an anti-HBV drug comprising:(a) introducing a resistance test vector comprising a patient-derived segment and an indicator gene into a host cell;(b) culturing the host cell from (a);(c) measuring expression of the indicator gene in a target host cell, wherein the expression of the indicator gene is dependent upon the patient- derived seqment; and(d) comparing the expression of the indicator gene from (c) with the expression of the indicator gene measured when steps (a)-(c) are carried out in the absence of the anti-HBV drug, wherein a test concentration of the anti-HBV drug is present at steps (a)-(c); at steps (b)-(c); or at step (c).