Patent ID: 8597684
Filing Date: 2013-12-03
Classification: A61K,A61P

Abstract:
1. An orally ingestible aqueous liquid suspension composition comprising: (A) barrier coated particulates which provide about a twelve hour release profile which comprise: (B) at least one additional component selected from the group consisting of at least one of (iiia) an uncoated particulate dextro-amphetamine—cation exchange resin complex of a size capable of passing through a number 40 mesh screen, wherein said uncoated dextro-amphetamine—cation exchange resin complex is a dextro-amphetamine bound to a pharmaceutically acceptable water insoluble cation exchange resin, and (iiib) an uncoated particulate amphetamine—cation exchange resin complex of a size capable of passing through a number 40 mesh screen, wherein said uncoated amphetamine—cation exchange resin complex is amphetamine bound to a pharmaceutically acceptable water insoluble cation exchange resin, (iiic) amphetamine or a pharmaceutically acceptable salt thereof which is not complexed with an ion exchange resin, or (iiid) dextroamphetamine or a pharmaceutically acceptable thereof which is not complexed with an ion exchange resin; and (C) a pharmaceutically acceptable aqueous suspension base, wherein said barrier coated particulate amphetamine—cation exchange resin complex—(water insoluble polymer or copolymer or said hydrophilic polymer) matrix defined in (A) and said at least one additional component defined in (B) are suspended in said base.