Patent ID: 6184016
Filing Date: 2001-02-06
Classification: C07K,C12N,Y10T

Abstract:
An isolated polypeptide, comprising:a) the amino acid sequence of SEQ ID NO:5;b) an amino acid sequence having at least 70% identity to a) and having prenylcysteine carboxyl methyltransferase (pcCT) activity either when isolated or when membrane bound;c) a fragment of a) or b) which has pcCMT activity either when isolated or when membrane bound; ord) a protein encoded by a nucleotide sequence which hybridizes to the complement of nucleotides 44 to 895 of SEQ ID NO:4 in 50% formamide and 5.times.SSC at 40.degree. C., followed by nonstringent washing, said protein having pcCMT activity either when isolated or when membrane bound.