Patent ID: 6489490
Filing Date: 2002-12-03
Classification: C07C,C07D

Abstract:
A compound of the formula (I) whereinAr represents the radical whereinm represents 0, 1, 2, 3 or 4, R1 represents halogen, cyano, trialkylsilyl, â€”COâ€”NR4R5, tetrahydropyranyl or represents one of the following groupings (l) â€”Xâ€”A (m) â€”Bâ€”Zâ€”D (n) â€”Yâ€”E, R2 represents hydrogen, halogen, cyano, nitro, alkyl, alkoxy, halogenoalkyl, halogenoalkoxy, alkoxyalkoxy or â€”S(O)oR3, o represents 0, 1 or 2, R3 represents alkyl or halogenoalkyl, R4 and R5 independently represent hydrogen, alkyl, halogenoalkyl or represent phenyl or phenylalkyl, each of which is optionally mono- or polysubstituted by radicals from the definition of W1 given below, X represents a direct bond, oxygen, sulphur, carbonyl, carbonyloxy, oxycarbonyl, alkylene, alkenylene, alkynylene, alkyleneoxy, oxyalkylene, thioalkylene, alkylenedioxy or dialkylsilylene, A represents phenyl, naphthyl or tetrahydronaphthyl, each of which is optionally mono- or polysubstituted by radicals from the definition of W1 given below, or represents 5- to 10-membered heterocyclyl containing one or two aromatic rings and having one or more heteroatoms selected from the group consisting of nitrogen, oxygen and sulphur and optionally mono- or polysubstituted by radicals from the definition of W2 given below, B represents p-phenylene which is optionally mono- or disubstituted by radicals from the definition of W1 given below, Z represents oxygen or sulphur, D represents hydrogen, alkyl, alkenyl, alkynyl, halogenoalkyl, halogenoalkenyl, optionally halogen-, alkyl-, alkenyl-, halogenoalkenyl-, phenyl-, styryl-, halogenophenyl- or halogenostyryl-substituted cycloalkyl or cycloalkylalkyl, represents optionally halogen- or alkyl-substituted cycloalkenyl or cycloalkenylalkyl, represents optionally nitro-, halogen-, alkyl-, alkoxy-, halogenoalkyl- or halogenoalkoxy-substituted phenylalkyl, naphthylalkyl, tetrahydronaphthylalkyl or hetarylalkyl having 5 or 6 ring members and one or two heteroatoms selected from the group consisting of nitrogen, oxygen and sulphur, represents â€”COâ€”R6, â€”COâ€”NR7R8 or represents the grouping â€”(CH2)pâ€”(CR9R10)qâ€”(CH2)râ€”G orZ and D together represent optionally nitro-, halogen-, alkyl-, alkoxy-, halogenoalkyl- or halogenoalkoxy-substituted phenoxyalkyl, Y represents a direct bond, oxygen, sulphur, carbonyl, carbonyloxy, oxycarbonyl, alkylene, alkenylene, alkynylene, alkyleneoxy, oxyalkylene, thioalkylene, alkylenedioxy or represents p-phenylene which is optionally mono- or disubstituted by radicals from the definition of W1 given below, E represents hydrogen, alkyl, alkenyl, alkynyl, halogenoalkyl, halogenoalkenyl, optionally halogen-, alkyl-, alkenyl-, halogenoalkenyl-, phenyl-, styryl-, halogenophenyl- or halogenostyryl-substituted cycloalkyl, represents optionally halogen- or alkyl-substituted cycloalkenyl, represents phenyl which is optionally mono- to tetrasubstituted by radicals from the definition of W1 given below or represents 5- or 6-membered hetaryl having one or two heteroatoms selected from the group consisting of nitrogen, oxygen and sulphur and optionally mono- to tetrasubstituted by radicals from the definition of W2 given below or represents the grouping â€”(CH2)pâ€”(CR9R10)qâ€”(CH2)râ€”G, R6 represents alkyl, alkoxy, alkenyl, alkenyloxy, optionally halogen-, alkyl-, alkenyl-, halogenoalkyl- or halogenoalkenyl-substituted cycloalkyl, cycloalkyloxy or cycloalkylalkyloxy or represents optionally nitro-, halogen-, alkyl-, alkoxy-, halogenoalkyl- or halogenoalkoxy-substituted phenyl or naphthyl, R7 represents hydrogen or alkyl, R8 represents alkyl, halogenoalkyl, optionally halogen-, alkyl-, alkenyl-, halogenoalkyl- or halogenoalkenyl-substituted cycloalkyl or cycloalkylalkyl or represents optionally halogen-, alkyl-, alkoxy-, halogenoalkyl- or halogenoalkoxy-substituted phenyl or phenylalkyl, p, q and r independently represent 0, 1, 2 or 3, with the sum of p, q and r being less than 6, R9 and R10 independently represent hydrogen or alkyl, G represents cyano, represents an optionally halogen-, alkyl- or halogenoalkyl- and, at the point of linkage, optionally R11-substituted 5- or 6-membered heterocycle having 1 to 3 heteroatoms selected from the group consisting of nitrogen, oxygen and sulphur or one of the following groups R11 represents hydrogen, alkyl, alkenyl, halogenoalkyl, halogenoalkenyl, optionally halogen-, alkyl- or halogenoalkyl-substituted cycloalkyl or represents phenyl which is optionally mono- to pentasubstituted by alkylcarbonylamino, alkylcarbonylalkylamino and/or radicals from the definition of W3 given below, R12 represents hydrogen, alkyl, alkenyl, halogenoalkyl, halogenoalkenyl, optionally halogen-, alkyl- or halogenoalkyl-substituted cycloalkyl or cycloalkylalkyl or represents arylalkyl which is optionally mono- to pentasubstituted by radicals from the definition of W3 given below, R13 and R14 independently represent hydrogen, alkyl, alkenyl, halogenoalkyl, halogenoalkenyl, alkoxy, optionally halogen-, alkyl- or halogenoalkyl-substituted cycloalkyl or cycloalkylalkyl, represents aryl or arylalkyl, each of which is optionally mono- to pentasubstituted by radicals from the definition of W3 given below, represent â€”OR12 or â€”NR11R12 or together represent an alkylene chain having 2 to 6 members in which optionally one methylene group is replaced by oxygen, R15 represents â€”OR12, â€”NR11R12 or â€”N(R11)â€”COOR12, R16, R17 and R18 independently represent alkyl, W1 represents hydrogen, halogen, cyano, formyl, nitro, alkyl, trialkylsilyl, alkoxy, halogenoalkyl, halogenoalkoxy, halogenoalkenyloxy, alkylcarbonyl, alkoxycarbonyl, pentafluorothio or â€”S(O)oR3, W2 represents halogen, cyano, formyl, nitro, alkyl, trialkylsilyl, alkoxy, halogenoalkyl, halogenoalkoxy, alkylcarbonyl, alkoxycarbonyl, pentafluorothio, â€”S(O)oR3 or â€”C(R11)&boxH;Nâ€”R15, W3 represents halogen, cyano, nitro, alkyl, alkoxy, halogenoalkyl, halogenoalkoxy, dialkylamino, â€”S(O)oR3, â€”COOR19 or â€”CONR20R21, R19 represents hydrogen, alkyl, halogenoalkyl, optionally halogen-, alkyl- or halogenoalkyl-substituted cycloalkyl or represents phenyl which is optionally mono- to pentasubstituted by radicals from the definition of W4 given below, R20 and R21 independently represent hydrogen, alkyl, alkenyl, halogenoalkyl, halogenoalkenyl, alkoxy, optionally halogen-, alkyl- or halogenoalkyl-substituted cycloalkyl or cycloalkylalkyl or represent aryl or arylalkyl, each of which is optionally mono- to pentasubstituted by radicals from the definition of W4 given below, represent â€”OR16 or â€”NR17R18 or together represent an alkylene chain having 2 to 6 members in which optionally one methylene group is replaced by oxygen, and W4 represents halogen, cyano, nitro, alkyl, alkoxy, halogenoalkyl, halogenoalkoxy, dialkylamino, alkoxycarbonyl, dialkylaminocarbonyl or â€”S(O)oR3.