Patent ID: 6201005
Filing Date: 2001-03-13
Classification: A61P,C07D,C07H,C12N,C12P,C12R,Y02P,Y10S

Abstract:
A method for inhibiting lymphokines production comprising administering to a subject in need thereof an amount of a compound of formula (I) effective to inhibit the production of lymphokines: ##STR16##whereinR.sup.1 is hydroxy or pharmaceutically acceptable protected hydroxy selected from the group consisting of 1-(lower alkylthio)(lower)alkyloxy, tri(lower)alkylsilyloxy, lower alkyl-diphenyl-silyloxy, pharmaceutically acceptable organic sulfonic acyloxy, and pharmaceutically acceptable organic carbamic acyloxy,R.sup.2 is hydrogen or the same meanings as R.sup.1,R.sup.3 is methyl, ethyl, propyl or allyl, n is an integer of 1 or 2, andthe symbol of a line and dotted line is a single bond or a double bond, or pharmaceutically acceptable basic salts thereof.