Patent ID: 6361790
Filing Date: 2002-03-26
Classification: A61F,A61K,Y10S

Abstract:
A method of forming a medication-containing adhesive patch that can be applied to the skin of a patient, the method comprising the steps of:(a) providing a backing layer having an upper portion and a lower portion, the backing layer comprising flexible, porous, and water insoluble material selected from: non-woven fabric, cellulose fiber, woven fabric, polymeric material, open-cell plastic foam, or a combination thereof; wherein the backing layer is non-occlusive, is in a sheet form, and serves as a support for the patch; (b) applying a hydrogel to the backing layer such that the hydrogel penetrates between about one-fourth to about nine-tenths the thickness of the backing layer, wherein the hydrogel comprises a polymer, a hydrophilic humectant, a medicament, and a hydrophilic adhesive substance; (c) limiting the penetration of the hydrogel within the backing layer to the lower portion of the backing layer; and (d) maintaining the upper portion of the backing layer essentially free of the hydrogel; thereby providing a medication-containing adhesive patch that can be applied to the skin of a patient.