Patent ID: 8980897
Filing Date: 2015-03-17
Classification: A61K,A61P,C07D,Y02A

Abstract:
1. A method of treating a disease, disorder, or condition involving TNFα production, wherein the method comprises administering a pharmaceutical composition to a subject, to inhibit the production of TNFα in the subject, wherein the pharmaceutical composition comprises a compound having the structure of formula (I), a salt thereof, or an enantiomer thereof, and a pharmaceutically acceptable carrier, in which: R R R R n can take the values of 0, 1, 2 or 3; and wherein the disease, disorder, or condition is selected from the group consisting of an inflammatory bowel disease (IBD), an inflammatory bone disease, transplant rejection, an autoimmune disease, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, juvenile chronic arthritis, multiple sclerosis, non-insulin-dependent diabetes mellitus, an allergic disease, asthma, chronic obstructive pulmonary disease (COPD), inflammatory skin disease, and ocular inflammation.