Patent ID: 6197806
Filing Date: 2001-03-06
Classification: A61K,A61P

Abstract:
A method for reducing free radicals or active oxygen in a patient in need of such reduction comprising administering to said patient a pharmaceutically effective amount of at least one hydantoin derivative or a pharmaceutically acceptable salt or complex of said derivative, said hydantoin derivative being represented by the formula (I): ##STR4##wherein each of R.sub.1 and R.sub.2, which may be the same or different, is hydrogen, an alkyl group or a cycloalkyl group; and each of X and Y, which may be the same or different, is hydrogen, a hydroxyl group, an alkyl group or an alkoxy group, or X and Y together is an oxo group, and wherein said patient is in need of treatment for a disease or a condition selected from the group consisting of myocardial infarction, reperfusion disturbance, autoimmune diseases, fibrosis, pulmonary diseases, dermatological diseases, arthropathy, side effects of anticancer agents, radiation diseases, septic shock and inflammatory diseases.