Patent ID: 6248573
Filing Date: 2001-06-19
Classification: C07C,C12P,Y02P,Y10S

Abstract:
A process for producing an (S)-1-phenyl-2-substituted propane derivative which comprises:allowing a sulfonylating agent or a halogenating agent to react with an (S)-1-phenyl-2-propanol derivative shown by the following formula ##STR12##wherein R.sup.1 and R.sup.2 represent (a) the same or different, a hydrogen atom or a protective group for hydroxyl group, or (b) R.sup.1 and R.sup.2 may form an optionally substituted ring together with the adjacent oxygen atoms; and R.sup.3, R.sup.4 and R.sup.5 independently represent a hydrogen atom, a lower alkyl group, a lower haloalkyl group, a lower alkoxy group, a nitro group or a halogen atom,to produce an (S)-1-phenyl-2-substituted propane derivative shown by the following formula ##STR13##wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the same meanings as defined above; and Y represents an optionally substituted alkylsulfonyloxy group, an optionally substituted arylsulfonyloxy group or a halogen atom.