Patent ID: 6620621
Filing Date: 2003-09-16
Classification: G01J,G01N

Abstract:
A method for identifying a patient at high risk for dysplasia utilizing single cell infrared microspectroscopy, said method comprising;(a) creating a reference set of absorption spectra from cervical cell samples taken from women having no history of dysplasia, each of said samples having a first cell exhibiting a first spectrum pattern and a second cell exhibiting a second spectrum pattern; (b) producing absorption data for a cervical cell sample acquired from said patient by directing a beam of infrared light at single cells in said cervical cell sample to produce absorption data for each of said single cells; (c) comparing said absorption data for said cervical cell sample acquired from said patient with said reference spectra, thereby generating comparison data; (d) generating scores for said absorption data using said comparison data; (e) creating frequency distribution profiles from said scores; and (f) detecting said high risk for dysplasia using said frequency distribution profiles.