Patent ID: 6696461
Filing Date: 2004-02-24
Classification: A61P,C07D

Abstract:
A compound of formula 1in whichR1 is methyl or hydroxymethyl, one of the substituents R2a and R2b is hydrogen and the other is hydroxyl, methoxy, ethoxy, propoxy, isopropoxy, butoxy, methoxyethoxy or methoxypropoxy, one of the substituents R3a and R3b is hydrogen and the other is hydrogen, hydroxyl, methoxy, ethoxy, propoxy, isopropoxy, butoxy, methoxyethoxy or methoxypropoxy, R4 is carboxyl, â€”CO-1-4C-alkoxy, hydroxy-1-4C-alkyl, 1-4C-alkoxy-1-4C-alkyl, 1-4C-alkoxy-1-4C-alkoxy-1-4C-alkyl, fluoro-1-4C-alkoxy-1-4C-alkyl or the radical â€”COâ€”NR5R6, whereR5 is hydrogen, 1-7C-alkyl, hydroxy-1-4C-alkyl or 1-4C-alkoxy-1-4C-alkyl and R6 is hydrogen, 1-7C-alkyl, hydroxy-1-4C-alkyl or 1-4C-alkoxy-1-4C-alkyl, or where R5 and R6 together with the nitrogen atom to which both are attached are a pyrrolidino, piperidino or morpholino radical, X is O (oxygen) or NH, or a salt thereof.