Patent ID: 9198873
Filing Date: 2015-12-01
Classification: A61K,A61L,A61P

Abstract:
1. A type of functionalized nanoparticles for drug delivery, comprising: a type of polymer nanoparticles, in which the polymer of said type of polymer nanoparticles is PLGA, collagen, gelatin, chitosan, chitin, hyaluronic acid, alginate, albumin, fibrin, agarose or cellulose; a single layer of polymer stabilizer coating, in which the polymer stabilizer is poly(ethylene)imine, polylysine or a polyamine material selected from the group of spermidine and putrescine; and a drug, which is a protein selected from a cytokine, a growth factor or a synthetic protein, wherein said polymer stabilizer coating is coated on the surface of said type of polymer nanoparticles, said drug is conjugated to said polymer stabilizer coating through an electrostatic interaction between the drug and the polymer stabilizer coating, and said nanoparticles have an average diameter of from 5 to 500 nm.