Patent ID: 6825003
Filing Date: 2004-11-30
Classification: A61K,C07K,C12N,C12P

Abstract:
A process for producing a cyclic peptide compound of the following formula (II): or a salt thereof, which comprises contacting a cyclic lipopeptide compound of the following formula (I): or a salt thereof in an aqueous solvent with a crude or purified enzyme solution, which is prepared by culturing Oidiodendron echinulatum IFO 31963, Oidiodendron tenuissimum IFO 6798, Oidiodendron truncatum IFO 9951, or Oidiodendron truncatum IFO 31812 in the presence of a cyclic lipopeptide compound; wherein R1 is acyl; R2 is hydroxyl or acyloxy; R3 is hydrogen or hydroxyl; R4 is hydrogen or hydroxyl; R5 is hydrogen or hydroxysulfonyloxy; and R6 is hydrogen or carbamoyl.