Patent ID: 8637657
Filing Date: 2014-01-28
Classification: A61K,A61P,C07K,C12P

Abstract:
1. A method of inhibiting S. aureus comprising the steps of inhibiting staphyloferrin A-mediated iron uptake in S. aureus by inhibiting the expression or activity of at least one of SbtA, SbtB, SbtC and SbtD or at least one of HtsA, HtsB and HtsC; and inhibiting staphyloferrin B-mediated iron uptake in S. aureus by inhibiting the expression or activity of at least one of SbnA, SbnB, SbnC, SbnD, SbnE, SbnF, SbnG, SbnH, and SbnI or at least one of SirA, SirB and SirC.