Patent ID: 6767719
Filing Date: 2004-07-27
Classification: A01K,C12N

Abstract:
An isolated, purified or recombinant polynucleotide encoding a telomerase reverse transcriptase protein, wherein said protein:(i) has at least 90% sequence identity to SEQ. ID NO:2; (ii) has telomerase catalytic activity when associated with telomerase RNA component; and (iii) contains at least one of the following amino acid motifs; Motif T: W-X12-FFY-X1-TE-X11-R-X3-W; Motif 1: LR-X1-IPK; Motif 2: R-X1-I-X15-K; Motif A: P-X3-F-X3-D-X4-YD; Motif B: Y-X4-G-X2-QG-X3-S; Motif C: DD-X1-L; or Motif D: A-X2-F-X18-K; wherein Xn is a sequence of unspecified amino acids of length â€œnâ€ .