Patent ID: 9138417
Filing Date: 2015-09-22
Classification: A01N,A61K

Abstract:
1. A controlled release particle comprising a core containing an antibiotic compound and a shell covering the core, wherein the controlled release particle is obtained by a production method including a first step in which a first component containing the antibiotic compound and a polymerizable vinyl monomer is subjected to suspension polymerization to form the core containing the antibiotic compound and a polymer of the polymerizable vinyl monomer, and a second step in which a second component containing a shell-forming component is subjected to interfacial polymerization to form the shell, wherein in the second step, the interfacial polymerization is started simultaneously with the start of the suspension polymerization of the first step, or started after the start of the suspension polymerization of the first step, and wherein the antibiotic compound has a polar term δ the polymer has a polar term δ