Patent ID: 7399772
Filing Date: 2008-07-15
Classification: A61K,A61P

Abstract:
1. A method for treating an acid-caused gastrointestinal disorder comprising the step of administering to a subject suffering from said disorder a solid pharmaceutical composition comprising: (a) about 10 mg to about 40 mg of non-enteric coated omeprazole; and (b) sodium bicarbonate in an amount of 0.2 mEq to 5 mEq per 2 mg omeprazole; wherein the composition contains no sucralfate, the acid-caused gastrointestinal disorder is selected from the group consisting of duodenal ulcer, gastric ulcer, gastroesophageal reflux disease, and erosive esophagitis, and the sodium bicarbonate is present in the composition in an amount sufficient to substantially prevent or inhibit acid degradation of at least some of the omeprazole by gastric acid upon administration to the subject.