Patent ID: 8802712
Filing Date: 2014-08-12
Classification: A61K,A61P,C07D,C12N

Abstract:
1. A compound of formula (I) in which R1 denotes Y, -Alk-OY, -Alk-NYY or -Alk-Ar, R2 denotes Y, -Alk-OY, -Alk-NYY, —C(Y)(R6)(R7), —C(Hal)(R6)(R7), —SO R3 denotes H, Hal, CN, -Alk-CN, -Alk-NYY, Het R4 denotes Hal, Y, Cyc, CN, -Alk-CN, -Alk-COOY, -Alk-CO—NYY or Het R5 denotes Hal, Y, OY, NYY, —NY—COY, COOY, —CO—NYY, —CO—NY-Alk-OY, -Alk-CO—NYY, -Alk-OY, -Alk-NYY, Ar, Het or R3, R5 together denote -Alk-CO—NY—, R6 denotes Hal, Y, —COOY, —CO—NYY, —CO—NY—OY, —CO—NY—C(═NH)—NYY, —CO—NY-Alk-OY, —CO—NY-Alk-NYY, —CO—NY-Alk-SO R7 denotes Ar, Het X denotes CH Y denotes H or A, A denotes unbranched or branched alkyl having 1-10 C atoms, in which, independently of one another, 1-7 H atoms may be replaced by Hal, and/or in which, independently of one another, one or two adjacent CH Alk denotes alkylene having 1-6 C atoms, in which, independently of one another, 1-4 H atoms are optionally replaced by Hal and/or OY, Cyc denotes cyclic alkyl having 3-7 C atoms, in which, independently of one another, 1-4 H atoms are optionally replaced by Hal and/or OY, Ar denotes phenyl which is unsubstituted or monosubstituted by Hal, A, CN, OY, NYY, —NY—COY, COOY, Het Het Het Hal denotes F, Cl, Br or I, or a pharmaceutically acceptable salt or tautomer thereof.