Patent ID: 7468419
Filing Date: 2008-12-23
Classification: A61K,A61P,C07K

Abstract:
1. A compound of formula I or a pro-drug, or an ester or a pharmaceutically acceptable salt thereof: and A is of the formula: wherein: Q is  where i) X is selected from hydrogen, halogen, C ii) one of Y and Z is selected from: hydrogen, deuterium, halogen, or methyl and the other is independently selected from: iii) G is independently selected from halogen, TMS, R B is selected from: i) -αAbu-; ii) -Val-; iii) -Thr-; or iv) -Nva-; U is selected from: i) -(D)Ala-; ii) -(D)Ser-; iii) -[O-(2-hydroxyethyl)(D)Ser]-; iv) -[O-(acyl)(D)Ser]-; or v) -[O-(2-acyloxyethyl)(D)Ser]-; and W is selected from hydrogen or a hydroxy protecting group.