Patent ID: 8759752
Filing Date: 2014-06-24
Classification: H01J

Abstract:
1. A method of determining a mass-to-charge ratio of an analyte in a sample, the method comprising: a) obtaining a mass spectrum, where the mass-to-charge ratio of the analyte was measured in a presence of a first adjacent ion, the first adjacent ion comprising an ion having a mass-to-charge ratio that is different than the mass-to-charge ratio of the analyte, the mass spectrum comprising: i) a measured analyte mass-to-charge ratio, ii) a measured first adjacent ion mass-to-charge ratio, iii) a measured analyte abundance, and iv) a measured first adjacent ion abundance, b) determining a first mass-to-charge ratio difference by subtracting the measured first adjacent ion mass-to-charge ratio from the measured analyte mass-to-charge ratio; and c) calculating a corrected analyte mass-to-charge ratio based on i) the measured analyte mass-to-charge ratio, ii) the measured analyte abundance, iii) the first mass-to-charge ratio difference, and iv) the measured first adjacent ion abundance, in accordance with the relationship: where M Δm=a mass correction offset.