Patent ID: 6121468
Filing Date: 2000-09-19
Classification: C07C,C07D

Abstract:
A method for producing a substituted 1-butene oxide derivative of the formula [XII] ##STR33## wherein R.sup.4 is an amino-protecting group, and R.sup.5 is a hydrogen atom, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted aryl or an optionally substituted aralkyl, or an enantiomer thereof, comprising treating a 3-substituted aminobutane derivative of the formula [XI] ##STR34## wherein R.sup.4 and R.sup.5 are as defined above, R.sup.6 is a hydroxy-protecting group and Z is a substituent which functions as a leaving group with an oxygen atom, or an enantiomer thereof, in the presence of a base, and simultaneously conducting epoxidation and deprotection of primary hydroxy.