Patent ID: 8389767
Filing Date: 2013-03-05
Classification: C07C

Abstract:
1. A method of using an intermediate in the production of a compound of formula (IV) wherein A R G each R Q wherein or an N-oxide or a salt thereof; wherein: a) the intermediate comprises a compound of formula (I) or an N-oxide or a salt thereof, and said method comprises (i) treating the compound of formula (I) with thionyl chloride in the presence of an aprotic solvent to form a compound of formula (II) or an N-oxide or a salt thereof, followed by (ii) treatment of the compound of formula (II) with an amine of formula HNR 2 Q 2 , under basic conditions, forming a compound of formula (III) or an N-oxide or a salt thereof, followed by (iii) treating the compound of formula (III) with water; or b) the intermediate comprises a compound of formula (II) or an N-oxide or a salt thereof, and said method comprises (i) treating the compound of formula (II) with an amine of formula HNR 2 Q 2 , under basic conditions, forming a compound of formula (III) or an N-oxide or a salt thereof, followed by (ii) treating the compound of formula (III) with water; or c) the intermediate comprises a compound of formula (III) or an N-oxide or a salt thereof, and said method comprises treating the compound of formula (III) with water.