Patent ID: 8993527
Filing Date: 2015-03-31
Classification: A61K,A61P

Abstract:
1. A method of reducing the incidence of mortality in a patient comprising administering to a patient in need thereof an effective amount of 5-amino-1-β-D-(5-benzylamino-5-deoxy-1-β-D-ribofuranosyl)imidazole-4-carboxamide, 5-amino-1-(5-amino-5-deoxy-β-D-ribofuranosyl) imidazole-4-N-[(4-chlorophenyl)methyl]carboxamide, or a salt thereof, wherein, prior to initial administration, said patient has decreased left ventricular function as measured by an ejection fraction that is less than 30%, and wherein, following the administration, the patient has improved left ventricular function.