Patent ID: 6488910
Filing Date: 2002-12-03
Classification: A61K,Y10T

Abstract:
A method of solubilizing gaseous hyperpolarized 129Xe, comprising the steps of:introducing a first quantity of microbubbles into a chamber; directing a second quantity of gaseous hyperpolarized 129Xe into the chamber such that at least a portion of the 129Xe contacts the microbubbles; introducing a third quantity of a liquid into the chamber such that at least a portion contacts the microbubbles; dissolving at least a portion of the 129Xe in the liquid; and separating substantially all of the microbubbles from the hyperpolarized 129Xe prior to delivery to a subject of the hyperpolarized 129Xe in the liquid thereby providing a formulation of dissolved hyperpolarized 129Xe.