Patent ID: 7145007
Filing Date: 2006-12-05
Classification: C07D

Abstract:
1. A process for the preparation of a (pyrimidin-2-yl)methyl ketone of the formula: in which R 1 is in each case a C 1-10 -alkyl group, a C 3-8 -cycloalkyl group, an allyl group or an aryl-C 1-4 -alkyl group, and R 2 is a C 1-10 -alkyl group or an aryl group, comprising reacting a malondiimidate of the formula: in which R 1 has the meaning given above, with a β-keto ester of the formula: in which R 2 has the meaning given above, and R 3 is a C 1-10 -alkyl group.