Patent ID: 6362276
Filing Date: 2002-03-26
Classification: A61K,C08G,C08L,Y10S

Abstract:
A hydrogel comprising a co-polymerization product of a multiacrylate and at least one compound selected from the group consisting of compounds represented by the formula:CH2&boxH;CZâ€”CO2â€”POLYâ€”Wâ€”POLYâ€²â€”Q1, (CH2&boxH;CZâ€”CO2â€”POLYâ€”Wâ€”POLYâ€²â€”L)xâ€”T, CH2&boxH;CZCO2â€”POLYâ€”Wâ€”Q, and(CH2&boxH;CZCO2â€”POLYâ€”Wâ€”L)xâ€”T, whereZ is H or an alkyl group; POLY and POLYâ€² are poly(alkylene oxides) that may be the same or different and are represented by the formula â€”(CH2CHRO)nâ€”CH2CHRâ€” in which R is H or alkyl, and n ranges from about 10 to about 4000; W represents a hydrolytically unstable linkage; Q represents a moiety reactive with a target molecule T; L is hydrolytically stable linkage; x is an integer of 1-10; and T is a target molecule.