Patent ID: 6472411
Filing Date: 2002-10-29
Classification: A61K,A61P,C07C,C07D,C07K,G01N

Abstract:
A method for treating or preventing proteinuria comprising administering to a mammal having an elevated blood sugar level an amount effective to prevent proteinuria of a compound of the general formula: wherein R1 is CH2NH2, CH2SH, COOH, CH2CH2NH2, CH2CH2SH, or CH2COOH; R2 and R6 are H, OH, SH, NH2, C 1-6 alkyl, alkoxy, alkene;R4 and R5 are H, C 1-6 alkoxy, or alkene; Y is N or C, such that when Y is N R3 is nothing, and when Y is C, R3 is NO2 or another electron withdrawing group, or salts thereof.