Patent ID: 8969630
Filing Date: 2015-03-03
Classification: C07C,C07D

Abstract:
1. A method of preparing chlorohydrins by reacting polyhydroxy aliphatic hydrocarbon with a chlorination agent in the presence of a catalyst, the method comprising at least one combination of a series of unit operations comprising a plurality of reaction steps and a water removal step in the following stated order: a first reaction step of reacting the polyhydroxy aliphatic hydrocarbon with the chlorination agent; a water removal step of removing water as a by-product from a reaction mixture discharged from the first reaction step; and a second reaction step of reacting at least one constituent of the dehydrated reaction mixture with at least one of the chlorination agent and an additional chlorination agent, wherein the method further comprises purifying a reaction mixture discharged from a final reaction step of the plurality of reaction steps to obtain a concentrate of chlorohydrins, wherein the catalyst comprises at least one selected from the group consisting of an organic acid catalyst, a carboxylic acid-based catalyst, a nitrile-based catalyst, and a solid catalyst, wherein an effluent of the first reactor introduced into the water removal step comprises the chlorination agent and water at a ratio of 10 to 25 parts by weight of the total of the chlorination agent and the additional chlorination agent and 75 to 90 parts by weight of water so that the effluent of the first reactor introduced into the water removal step forms an azeotropic mixture.