Patent ID: 6455585
Filing Date: 2002-09-24
Classification: A61P,C07B,C07C,C07D

Abstract:
A Compound of formula (I): R2 is: OH; R3 is: H; or R2 and R3 together form a double bond; R4 is: H or C1-C2 alkyl; R5 is: H, NH2, NHâ€”R11 or Oâ€”R11; R6 is: H, COâ€”R11, Oâ€”R11 or halogen; R7 is: H, C1-C5 alkyl, C2-C5 O-alkenyl, phenyl, or R6 and R7 are â€”CH&boxH;CR12â€”CR13&boxH;CHâ€”, forming an unsubstituted or substituted with R12 or R13 condensed aromatic ring; R8 is: OH, â€”Oâ€”COâ€”N(CH3)2 or NHâ€”R11; R11 is: phenyl; phenyl unsubstituted or substituted by 1 or more of the following substituents: halogen (Cl, Br, I), NO2, C1-C6 alkyl, C2-C6 alkenyl, OH, or NH2; R12 and R13 are: H, or C1-C3 O-alkyl, whether equal or different; its salts and optical isomers.