Patent ID: 7410947
Filing Date: 2008-08-12
Classification: A61F,A61L,A61P,Y10S

Abstract:
1. A method for inducing local bone or cartilage formation, comprising the step of providing to a defect site a device comprising: (a) a bone morphogenetic protein selected from the group consisting of OP1, OP2, OP3, BMP2, BMP3, BMP4, BMP5, BMP6, BMP9, BMP10, BMP11, BMP12, BMP15, BMP16, DPP, Vgl, 60A protein, GDF-1, GDF3, GDF5, GDF6, GDF7, GDF8, GDF9, GDF10 and GDF11; (b) a matrix selected from the group consisting of collagen, apatites, hydroxyapatites, tricalcium phosphate, and admixtures thereof; and (c) a binding agent selected from the group consisting of cellulosic agents and salts thereof wherein said binding agent has a degree of substitution of 0.65-0.90 and a viscosity of about 10-200 cP at a 4% (w/v) concentration of said binding agent.