Patent ID: 8088749
Filing Date: 2012-01-03
Classification: A61K,A61P

Abstract:
1. A method for treating a human subject with pancreatic cancer comprising: administering an agent that inhibits human ATDC expression or activity to a human subject that has pancreatic cancer, wherein said agent comprises an oligonucleotide that functions via RNA interference, wherein said oligonucleotide consists of a sequence selected from the group consisting of: SEQ ID NO:38 (miR-34a), SEQ ID NO:24 (miR-34c), SEQ ID NO:43 (miR-296-5p), SEQ ID NO:44 (miR-296-3p), SEQ ID NO:40 (miR-650), SEQ ID NO:16 (miR-299-5p), SEQ ID NO:18 (miR-185), SEQ ID NO:26 (miR-765), SEQ ID NO:20 (miR-522), and SEQ ID NO:30 (miR-362).