Patent ID: 6096930
Filing Date: 2000-08-01
Classification: A01N,C07C

Abstract:
A process for the preparation of 2-methyl-2-alkylindanaldehyde of formula (7), which consists ofpreparing the 2-methyl-2-alkylindan-1,3-dione of formula (9) by reacting the benzene derivative of formula (8) with a malonyl halide of the formula ##STR13## in the presence of Lewis acid; preparing the 2-methyl-2-alkylindane of formula (10) by reduction of the above compound (9) in the presence of hydrochloric acid and zinc-mercury alloy (Zn/Hg); andreacting the compound (10) with .alpha.,.alpha.-dichloromethyl methyl ether in the presence of Lewis acid as catalyst, ##STR14## wherein X is selected from the group consisting of hydrogen, halogen, C.sub.1 .about.C.sub.8 alkyl, C.sub.2 .about.C.sub.6 alkoxy, C.sub.1 .about.C.sub.6 haloalkyl, nitro, C.sub.1 .about.C.sub.6 alkylthio, C.sub.1 .about.C.sub.6 alkylsulfinyl, C.sub.1 .about.C.sub.6 alkylsulfonyl, C.sub.1 .about.C.sub.6 sulfamoyl, and N,N-di(C.sub.1 .about.C.sub.6 alkyl) sulfamoyl;(X)n represents the number of X substituents which may be substituted on the benzene ring, wherein n is 1, 2, or 3; andR.sup.1 is selected from the group consisting of hydrogen and C.sub.1 .about.C.sub.6 alkyl.