Patent ID: 7910318
Filing Date: 2011-03-22
Classification: C12Q,G01N

Abstract:
1. A method of diagnosing ovarian cancer in a sample from a subject comprising: (a) detecting the expression level of each of the markers FGF-2 and CA125 in the sample from the subject, wherein the subject is an adult woman; and (b) comparing the expression level of each of the markers in the sample from the subject to (i) the corresponding pre-determined threshold expression level for each of the markers; (ii) the expression level of each of the markers in a control sample; (iii) the expression level of each of the markers in a sample from the subject at an earlier time; or (iv) the expression level of each of the markers in a non-cancerous sample from the subject, and (c) determining whether the results indicate or not that the subject has ovarian cancer, wherein an expression level of each of the markers in the sample from the subject that is higher than (i) the pre-determined threshold expression levels for each of the markers; (ii) the expression level of each of the markers in the control sample; (iii) the expression level of each of the markers in a sample from the subject at an earlier time; or (iv) the expression level of each of the markers in a non-cancerous sample from the subject, is an indication that the subject has ovarian cancer.