Patent ID: 8669227
Filing Date: 2014-03-11
Classification: A61K,A61P

Abstract:
1. A water soluble non-covalent complex between an insulin and a polysaccharide comprising carboxyl functional groups, wherein said polysaccharide is a polysaccharide functionalized with at least one phenylalanine (abbreviated Phe), said phenylalanine being grafted or bonded onto the polysaccharide by coupling with an acid group, said acid group being borne by a linker arm R bonded to the polysaccharide via a group F, said group F resulting from coupling between the linker arm R and an —OH group of the polysaccharide and/or borne by the polysaccharide comprising carboxyl functional groups, wherein: F is either an ester, thioester, carbonate, carbamate or ether group; R is