Patent ID: 6733745
Filing Date: 2004-05-11
Classification: A61K,A61P,A61Q,Y10T

Abstract:
A device for delivering chlorhexidine gluconate to the oral environment, said device comprising a coating comprising:a) chlorhexidine gluconate b) Solubilizing Glycol, and c) a surfactant that contains both (a) hydrophilic group(s) capable of dispersing chlorhexidine gluconate and a glycol, and (b) an alkyl group(s), said coating comprising no more than about 2% water by weight and having less than 0.5 molar equivalents of deleterious quantities of salts, acids, and bases that would react with chlorhexidine gluconate based an the amount of chlorhexidine gluconate in the coating, and said coating containing no more than 200 ppm of PCA after four weeks at 45Â° c.