Patent ID: 8038999
Filing Date: 2011-10-18
Classification: A61K,A61P,C07K,G01N

Abstract:
1. A method to aid in deterring the occurrence, growth or progression of breast cancer in a population of susceptible individuals, the method comprising: identifying individuals having a localized tumor or mastectomy or lumpectomy site including ER+ breast cancer cells, administering locally to said localized tumor or mastectomy or lumpectomy site in said identified individuals a pharmaceutically acceptable form of a source of iron in a suitable carrier, wherein said source of iron comprises Fe(II), Fe(III), radioactive Fe(II) or Fe(III), or Fe(III)-bound transferrin or apotransferrin molecules that are also bound to another radioactive metal, wherein the iron in said source of iron is present at a concentration sufficient to kill at least a portion of the ER+ breast cancer cells in said tumor or at said mastectomy or at said lumpectomy site.