Patent ID: 7122540
Filing Date: 2006-10-17
Classification: A61P,C07D,C07F

Abstract:
1. A method for the treatment of hypertension, comprising administering to a mammal an effective amount of a compound of the formula (I) in which R R R or R or R R R and/or R R and/or R or represents cycloalkyl having 3 to 8 carbon atoms, aryl having 6 to 10 carbon atoms or represents a 5- to 7-membered partially unsaturated, saturatad or unsaturated, optionally beuzo-fused heterocycle which may contain up to 4 heteroatoms from the group consisting of S, N and O, or a radical of the formula —NR in which R in which e represents a number 0 or 1, R R R and/or cycloalkyl, aryl and/or the heterocycle are optionally substituted by straight-chain or branched alkyl having up to 6 carbon atoms which is optionally substituted by hydroxyl, carboxyl, by a 5- to 7-membered heterocycle having up to 3 heteroatoms from the group consisting of S, N and O, or by groups of the formula —SO in which R R R R or R or R or E represents radicals of the formulae and the heterocycle listed under R ═NR 48 or —(CO) i NR 49 R 60 in which R R j represents a number 0 or 1, and R or R R or their salts, hydrates, N-oxides, and structural isomers.