Patent ID: 7335378
Filing Date: 2008-02-26
Classification: A61K,A61L,B32B

Abstract:
1. A method for reducing cold flow in a therapeutically active substance-containing therapeutic system which is in the form of an adhesive patch, said method comprising the steps of laminating a first layer comprising a polymer having a glass transition temperature (T g 1 ) onto a second layer comprising a polymer having a glass transition temperature (T g 2 ), and subsequently laminating a third layer on said second layer, said third layer comprising a polymer having a glass transition temperature (T g 3 ), wherein T g 2 is greater than T g 1 and T g 3 , and the glass transition temperature T g 1 of the polymer of said first layer and the glass transition temperature T g 3 of the polymer of said third layer are identical or different, and adding at least one therapeutically active substance to at least one of said layers, said second layer reducing cold flow in said system.