Patent ID: 6989393
Filing Date: 2006-01-24
Classification: A61P,C07D

Abstract:
1. A compound of formula (Ih): wherein R 1 is CR 80 R 81 CR 82 R 83 R 84 ; R 84 is CR 88 R 89 R 90 ; R 80 , R 81 , R 82 , R 83 and R 88 are, independently, hydrogen or C 1-4 alkyl; R 89 is phenyl or heteroaryl; R 90 is C 1-4 alkyl, phenyl, or heteroaryl; R 2a , R 2b , R 2c and R 2d are, independently, hydrogen, halogen, cyano, or S(O) 2 (C 1-4 alkyl); and R 5 is hydrogen or C 1-4 alkyl; wherein the foregoing phenyl and heteroaryl groups and moieties are optionally substituted by halogen or CF 3 ; or pharmaceutically acceptable salt thereof.