Patent ID: 6329524
Filing Date: 2001-12-11
Classification: A61P,C07D

Abstract:
A compound represented by the formula (II): ##STR73##or a pharmaceutically acceptable salt, prodrug or ester thereofwhereint represents 0,1 and 2;Y' represents O, S and NR.sup.15 wherein R.sup.15 represents hydrogen, alkyl, haloalkyl, alkenyl, alkynyl, hydroxyalkyl, alkoxyalkyl, cycloalkyl, cycloalkylalkyl, heterocycloalkyl, heteroaryl, heterocycloalkylalkyl, aryl, aralkyl, heteroaralkyl, aminoalkyl and mono- and disubstituted aminoalkyl radicals, wherein said substituents are selected from alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl, heteroaryl, heteroaralkyl, heterocycloalkyl, and heterocycloalkylalkyl radicals, or in the case of a disubstituted aminoalkyl radical, said substituents along with the nitrogen atom to which they are attached form a heterocycloalkyl or a heteroaryl radical, thioalkyll, alkylthioalkyl, and arylthioalkyl radicals and the sulfone or sulfoxide derivatives thereof;R.sup.2 represents alkyl, aryl, cycloalkyl, cycloalkylalkyl, and aralkyl radicals, which radicals are optionally substituted with a substituent selected from the group consisting of alkyl radicals, --NO.sub.2, CN, CF.sub.3, --OR.sup.9, --SR.sup.9, and halogen radicals, wherein R.sup.9 represents hydrogen and alkyl radicals;R.sup.6 represents hydrogen and alkyl radicals; andwherein ##STR74##