Patent ID: 8133726
Filing Date: 2012-03-13
Classification: A61K,A61P,C12N

Abstract:
1. A non-naturally occurring antigen-presenting cell derived from Drosophila melanogaster comprising cell surface MHC class I and at least one antigenic peptide from human CD40L wherein the antigen presenting cell is capable of activating CD8+ cells and wherein at least one human CD40L peptide is selected from the group consisting of: FELQPGASV (SEQ ID NO: 40˜), QLTVKRQRL (SEQ ID NO: 41), QMIGSALFA (SEQ ID NO: 42), SQAPFIASL (SEQ ID NO: 43), ISMKIFMYL (SEQ ID NO: 44), VTLENGKQLL (SEQ ID NO: 45), VISEASSKT (SEQ ID NO: 46), GVFELQPGA (SEQ ID NO: 47), SMKIFMYLL (SEQ ID NO: 48), and RQGLYYIYA (SEQ ID NO: 49).