Patent ID: 6677350
Filing Date: 2004-01-13
Classification: A61K,A61P

Abstract:
A method for preventing or treating a mycobacterium infection in a mammal comprising administering to a mammal in need of anti-mycobacterium prevention or treatment an effective anti-mycobacterium amount of at least one compound of formula ii: wherein R1=4-fluorophenyl-, 3-hydroxyphenyl-, pyridin-3-yl-, furan-2-yl-, phenanthren-2-yl-, 3-fluorenyl-, pyridin-2-yl-, naphthalen-1-yl-, pyridin-2-yl-, 4-bromo-2-hydroxyphenyl-, pyridin-4-yl-, 2-hydroxy-4-methoxyphenyl-, 4-aminophenyl-, pyridin-4-yl-, 2-hydroxy-5-methoxyphenyl-, 4-methoxyphenyl-, 4-methoxyphenyl-, 2-hydroxy-5-chlorophenyl-, 4-aminophenyl-, 3-hydroxynaphthalen-2-yl-, furan-2-yl- or pyridin-2-yl-; andR2=pyridin-3-yl-, phenanthren-9-yl-, phenanthren-9-yl-, phenyl-, 2-aminopyridino-3-yl, 2-aminopyridino-3-yl-, pyridin-2-yl-, phenyl-, 4-dimethylaminophenyl-, furan-2-yl-, indol-2-yl-, furan-2-yl-, 2-aminopyridin-3-yl-, 4-dimethylaminophenyl-, furan-2-yl-, pyridin-4-yl-, pyridin-3-yl-, 2-amino-pyridin-3-yl-, 2-aminopyridin-3-yl-, 2-aminopyridin-3-yl-, pyridin-4-yl- or 4-methoxyphenyl-; or a pharmaceutically acceptable derivative or salt thereof and a pharmaceutically acceptable carrier therefor.