Patent ID: 6127360
Filing Date: 2000-10-03
Classification: A61P,C07D

Abstract:
A compound represented by the following formula or a salt, solvate or isomer thereof: ##STR11## wherein R.sup.1 is selected from the group consisting of a hydrogen atom, a hydroxyl group, an aralkyloxy group and a halogen atom,R.sup.2 is selected from the group consisting of a hydrogen atom and a lower alkyl group,A is selected from the group consisting of --O--, --S--, --CH.dbd.CH--, --COH.dbd.CH--, --CH.dbd.N--, and --N--(R.sup.4), wherein R.sup.4 is a lower alkyl group or an alkoxyalkyl group,B is selected from the group consisting of a single bond, --CH.dbd.CH--, --S(O).sub.q CH.sub.2 --, --S(O).sub.q CHOH--, CHOH--, and --C(R.sup.5)(R.sup.6)--(CH.sub.2).sub.k --, wherein R.sup.5 and R.sup.6 are the same or different and are either a hydrogen atom or a lower alkyl group, q is a value of 0 to 2, and k is a value of 0 to 2,E is selected from the group consisting of a single bond and --(CH.sub.2).sub.3 --,W is selected from the group consisting of --CH.sub.2 -- and --CO--,Y is selected from the group consisting of --CH.sub.2 -- and --CO--,Z is selected from the group consisting of O and S, and(l) is a value of either 0 or 1, m is a value of either 2 or 3, and n is a value of 1 to 4;wherein when E is ""--(CH.sub.2).sub.3 --"" then B is a single bond, and when E is a single bond, then B is a group other than a single bond.