Patent ID: 7883722
Filing Date: 2011-02-08
Classification: A61K

Abstract:
1. A composition for controlled delivery of at least one drug into an aqueous medium by erosion at a preprogrammed rate of at least one surface of the composition, the composition comprising (A) a matrix which is erodible in the aqueous medium in which the composition is to be used and which allows substantially no diffusion of water into the composition beyond any exposed surface layers of the matrix, wherein the matrix comprises, substantially homogeneously distributed in the matrix, (B) a coating on the matrix having at least one opening exposing at least one surface of the matrix, the coating being one which crumbles and/or erodes upon exposure to the aqueous medium at a rate which is equal to or slower than the rate at which the matrix erodes in the aqueous medium, allowing exposure of said surface of the matrix to the aqueous medium to be controlled.