Patent ID: 9107575
Filing Date: 2015-08-18
Classification: A61B,G02B

Abstract:
1. A device for imaging the brain of a freely moving animal, comprising: a first part of the device that is configured to be fixed on the skull of the freely moving animal over an orifice drilled in the skull, wherein the first part is an intracranial implant comprising a base support and a first locking member; and a second part of the device configured to be operatively connected to the first part, wherein the second part is removable and comprises a fiber bundle for transporting light and a second locking member, wherein the fiber bundle comprises a proximal tip and a distal tip, and wherein the second locking member comprises two halves forming an arch into which the first locking member fits, the proximal tip of the fiber bundle being operatively connected to a system for confocal fluorescence microscopy imaging, and the distal tip of the fiber bundle being configured to be inserted in the brain of the freely moving animal to image a tissue sample of the brain of the freely moving animal, wherein the intracranial implant further comprises a hollow conduit arranged through the base support to guide the fiber bundle to the brain of the freely moving animal through the drilled orifice, and wherein the first and second locking members block the fiber bundle on a determined region of the brain to image when the fiber bundle is inserted into the hollow conduit.