Patent ID: 8575197
Filing Date: 2013-11-05
Classification: A61P,C07D

Abstract:
1. A compound represented by the formula (I′): wherein Z Z t′ is an integer of 0; R m′ and n′ are each independently an integer of 0 to 2; Ring A′ is cycloalkane, cycloalkene, an aromatic carbocyclic ring or a heterocyclic ring; B′ is cycloalkane-diyl, cycloalkene-diyl, aromatic carbocyclic ring-diyl or heterocyclic ring-diyl, or; when n′ is 0, B′ may be methylthio, is methylthio, trifluoromethylthio, or —C(R R R R R wherein Y′ is —O—, —S—, or —NR R Z′ is hydroxy, substituted or unsubstituted lower alkoxy, substituted or unsubstituted lower alkylthio, substituted or unsubstituted acyl, carboxy, substituted or unsubstituted lower alkoxycarbonyl, substituted or unsubstituted carbamoyl, substituted or unsubstituted amino, substituted or unsubstituted lower alkylsulfinyl, substituted or unsubstituted alkylsulfamoyl or cyano; R s′ is an integer of 1 to 4, or its pharmaceutically acceptable salt thereof.