Patent ID: 6468667
Filing Date: 2002-10-22
Classification: A61L,G02B,Y10T

Abstract:
An ophthalmic molding comprising(a) a bulk material carrying covalently linked photoinitiator molecules for radical polymerization on its surface; and (b) a surface coating obtained by co-graft polymerizing onto the bulk material surface: (i) one or more different acceptor saccharides comprising an ethylenically unsaturated double bond; and (ii) one or more hydrophilic macromonomers of formula â€ƒwherein R4* is hydrogen or methyl, A1 is â€”Oâ€”(CH2)2-4â€”, â€”Oâ€”CH2â€”CH(OH)â€”CH2â€” or a radical â€”Oâ€”(CH2)2-4â€”NHâ€”C(O)â€”, X is â€”Oâ€” or â€”NHâ€”, (alk) is C2-C4-alkylene, Q is a monovalent group that is suitable to act as a polymerization chain-reaction terminator, p is an integer from 5 to 50, R3â€² is hydrogen or methyl, and â€ƒis the 1,2-ethylene radical derived from acrylamide, N,N-dimethyl acrylamide or N-vinylpyrrolidone, wherein, before or after said graft polymerization, a further carbohydrate selected from the group consisting of a galactose, mannose, fucose, galactosamine, N-acetylgalactosamine, N-acetylglucosamine, sialic acid and an oligosaccharide, is enzymatically attached to the acceptor saccharide.