Patent ID: 7795267
Filing Date: 2010-09-14
Classification: A61P,C07D

Abstract:
1. A compound represented by the formula: wherein R R R R R R (i) a hydrogen atom, (ii) a C (iii) a C (iv) a phenyl group which may have substituent(s) selected from a halogen atom and a C (v) a benzyl group, R (i) a C (ii) a C (iii) a phenyl group which may have substituent(s) selected from a halogen atom and a C (iv) a benzyl group, R n is an integer from 0 to 4 (when n is an integer from 2 to 4, R X is an oxygen atom, Group A: a halogen atom, a C a nitro group, a cyano group, a C a C a carboxy-C a C a C a C a C a C a hydroxy group, a C a C a mercapto group, a C a C a C an amino group, a mono-C a di-C a mono- or di-C a sulfonyl-amino group which may be substituted with a benzene ring which may be substituted with a nitro group, a C a C a C a C a C C an azidocarbonyl-amino group, an aminocarbonylamino group, a C a formyl group, a carboxy group, a C a C a C a 5- to 7-membered cyclic amino-carbonyl group, a C a C a C a C a 5- to 6-membered heterocyclic carbonyl group, a carbamoyl group, a mono-C a di-C a C a 5- to 6-membered heterocyclic carbamoyl group, a C a C a formylamino group, a C a C a C a C a C a C a C a C a mono-C a di-C a C a 5- to 6-membered heterocyclic carbonyloxy group, a 5- to 10-membered cyclic amino group which may have substitutent(s) selected from the following Group C and may be condensed with a benzene ring, a 5- or 7-membered non-aromatic heterocyclic group which may have substitutent(s) selected from the following Group D, a 5- to 10-membered aromatic heterocyclic group which may have substitutent(s) selected from the following Group D, a sulfo group, and an oxo group; Group B: (i) a halogen atom, (ii) an amino group which may have one or two substituents selected from a halogen atom, a C (iii) a 5- to 10-membered aromatic heterocyclic group which may be oxidized and may have a cyano group, (iv) a 5- to 7-membered cyclic amino group which may be have one to five C (v) a C (vi) a carboxy group, (vii) a 5- to 7-membered saturated cyclic amino-carbonyl group, (viii) a C (ix) a C (x) a hydroxy group, (xi) a C (xii) a C (xiii) a carbamoyl group; Group C: a C a hydroxy group, a C a C a C a 5- to 10-membered aromatic heterocyclic group, and an oxo group; Group D: a C a hydroxy group, a cyano group, a C a C a 5- to 10-membered aromatic heterocyclic group, and an oxo group; or a pharmaceutically acceptable salt thereof.