Patent ID: 8029982
Filing Date: 2011-10-04
Classification: G01N

Abstract:
1. A method of diagnosing sepsis in a human subject suspected of having sepsis, comprising: determining a concentration of at least one analyte in a fluid test sample from said human subject; comparing the concentration of each said analyte(s) to a corresponding reference concentration selected to indicate the presence or absence of sepsis, wherein said reference concentration is determined using one or more control samples obtained from one or more human subjects not suffering from sepsis, provided that at least one of said analyte(s) is myeloid progenitor inhibitory factor-1 (“MPIF-1”), wherein an elevation in concentration of said analyte(s) in the test sample of at least about two fold relative to the reference concentration is indicative of the presence of sepsis in the human; and diagnosing sepsis in the human subject using the result(s) of said comparing step.