Patent ID: 9061001
Filing Date: 2015-06-23
Classification: A61K,A61P,C07K,C12N

Abstract:
1. An adjuvant composition comprising a host defense peptide, an immunostimulatory sequence and a polyanionic polymer, wherein the polyanionic polymer is poly[di(sodium carboxylatophenoxy)phosphazene] (PCPP), poly(di-4-oxyphenylproprionate)phosphazene (PCEP), or a PCPP polymer comprising 90% PCPP copolymer with 10% hydroxyl groups (90:10 PCPP), wherein said adjuvant composition is capable of enhancing a protective immune response to a selected antigen from a pathogen as compared to the immune response elicited by an equivalent amount of the antigen when delivered without an adjuvant composition.