Patent ID: 6461587
Filing Date: 2002-10-08
Classification: A61K

Abstract:
A metal complex of the formula I in whichK is a complexing agent or a metal complex of the formula II whereR1 is a hydrogen atom or a metal ion equivalent of atomic numbers 21-29, 31, 32, 37-39, 42-44, 49 or 57-83, R2 and R3 are independently a hydrogen atom, a C1-C7 alkyl group, a benzyl group, a phenyl group, â€”CH2OH or â€”CH2â€”OCH3, U has the same meaning as L, where L and U, independently of one another, can be the same or different, A is a â€”Lâ€”RF group, a hydrogen atom, or a straight-chain or branched C1-C30 alkyl group, which optionally is interrupted by 1-15 oxygen atoms and/or optionally is substituted with 1-10 hydroxy groups, 1-2 COOH groups, a phenyl group, a benzyl group and/or 1-5 â€”OR4 groups, where R4 is a hydrogen atom or a C1-C7 alkyl radical, L is a straight-chain or branched C1-C30 alkylene group, which optionally is interrupted by: 1-10 oxygen atoms; 1-5 â€”NH-â€”COâ€”groups; 1-5â€”COâ€”NHâ€” groups; a phenylene group that is optionally substituted by a COOH group; 1-3 sulfur atoms; 1-2â€”N(B1)â€”SO2â€” groups; and/or 1-2â€”SO2â€”N(B1)â€” groups; where B1 independently is as defined for A; and/or the alkylene group optionally is substituted with a RF group; and RF is a straight-chain or branched perfluorinated alkyl radical of the formula CnF2nX, where 4&lE;n&lE;20 and X is a terminal fluorine atom, chlorine atom, iodine atom or hydrogen atom, and any â€”COOH acid groups in the complex optionally are in the form of a salt of an organic and/or inorganic base or amino acid or amino acid amide.