Patent ID: 6316483
Filing Date: 2001-11-13
Classification: A61K,Y10S

Abstract:
An aqueous nasal spray composition comprising:a medicament selected from the group consisting of 0.001-2% by weight/volume of chlorpheniramine maleate, 0.001-0.2% by weight/volume of oxymetazoline hydrochloride, or mixtures thereof;0.50 to 15.00% by weight/volume of a water soluble polymer selected from the group consisting of polyvinylpyrrolidone having an average molecular weight of about 10,000 to 360,000 and mixtures thereof;0.00 to 15.00% by weight/volume of polyethylene glycol;0.00 to 10.00% by weight/volume of moisturizing agent other than polyethylene glycol;0.00 to 10.00% by weight/volume of an antioxidant;0.001 to 0.3% by weight/volume of an antimicrobial preservative;0.00 to 5.00% by weight/volume of an aromatic alcohol;a sufficient amount of a pharmaceutically acceptable buffer to maintain the pH of the composition within the range of about 4.0 to 8.0; andQS water.