Patent ID: 6022477
Filing Date: 2000-02-08
Classification: B01D,C07K

Abstract:
A method of recovering bioproducts from a feed solution, the method comprising:providing a membrane module comprising a housing, at least one hollow fiber membrane disposed within the housing and having a feed side and a permeate side, a permeate outlet which extends outside of said housing, and a continuous packed bed of adsorbent particles in contact with the permeate side of said membrane, said particles being disposed within the housing and extending outside of said housing into said permeate outlet;passing the feed solution into the membrane module to contact the feed side of the membrane;separating bioproducts from the feed solution by permeation through to the permeate side of the membrane and allowing the permeated bioproducts to contact the adsorbent particles, wherein the bioproducts are retained by the adsorbent particles, whereby the bioproducts are isolated from the feed solution; andfractionating and purifying the retained bioproducts from the bed by chromatographic elution.