Patent ID: 6407136
Filing Date: 2002-06-18
Classification: C07D

Abstract:
A compound of the formula whereinR1 is selected from the group consisting of substituted arC1-C8 alkyl where the substituent is NR3R4; R2 is selected from the group consisting of C1-C8 alkyl, unsubstituted or substituted aryl, and unsubstituted or substituted heteroaryl, where the substituents on the aryl or heteroaryl are independently selected from one or more of halogen, C1-C8 alkyl, C3-C8 cycloalkyl, C1-C8 alkoxy, fluorinated C1-C8 alkyl, fluorinated C1-C8 alkoxy, aryloxy, C1-C8 alkylamido, aryl, carboxy, C1-C8 alkoxycarbonyl, aryloxycarbonyl, arylsulfonyl, or arC1-C8 alkylamido; and R3 and R4 are independently selected from hydrogen, C1-C8 alkyl, benzoyl or substituted benzoyl where the substituent is C1-C8 alkoxy; provided that when R2 is poly-substituted phenyl, the substituents are independently selected from two or more of halogen, C1-C8 alkyl, C3-C8 cycloalkyl, C2-C8 alkoxy, fluorinated C1-C8 alkyl, fluorinated C1-C8 alkoxy, aryloxy, C1-C8 alkylamido, aryl, carboxy, C1-C8 alkoxycarbonyl, aryloxycarbonyl, arylsulfonyl, or arC1-C8 alkylamido; and pharmaceutically acceptable salts thereof.