Patent ID: 6534524
Filing Date: 2003-03-18
Classification: C07D

Abstract:
A compound of the Formula I: wherein:R1 is an unsubstituted aryl or substituted or unsubstituted heteroaryl, or a group of the formula CH&boxH;CHâ€”R3 or CH&boxH;Nâ€”R3 where R3 is a substituted or unsubstituted alkyl, alkenyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl; and R2 is a substituted or unsubstituted aryl, heteroaryl, or Yâ€”X, where Y is O, S, C&boxH;CH2, C&boxH;O, S&boxH;O, SO2, alkylidene, or Nâ€”(C1-C8 alkyl), and X is substituted or unsubstituted Ar, heteroaryl, NHâ€”(alkyl), NHâ€”(cycloalkyl), NHâ€”(heterocycloalkyl), NH(aryl), NH(heteroaryl), NHâ€”(alkoxyl), or NHâ€”(dialkylamide), where Ar is aryl; or a pharmaceutically acceptable prodrug, pharmaceutically active metabolite, or pharmaceutically acceptable salt thereof.