Patent ID: 6251625
Filing Date: 2001-06-26
Classification: C07K,C12P,Y02P

Abstract:
Process for the preparation of peptides of the structure I, ##STR7##whereinR.sup.1 and R.sup.2 independently of one another denote hydrogen, (C.sub.1 -C.sub.6 Q.sub.n) alkyl, where n=0-5 and wherein Q isa mono or poly substitutuent on a carbon and a member of the group consisting of heteroatoms of the group consisting of N, O and S, said heteroatoms being unsubstituted or mono or poly substituted wherein the substituent is a member of the group consisting of hydrogen, (C1-C4) alkyl and benzyl, or being bonded to said (C.sub.1 C.sub.6) alkyl group via a double bond,unsubstituted or mono or Poly substituted phenyl or benzyl, wherein the substituent is a member of the group consisting of halogen or hydroxyl and heteroaralkyl,R.sup.3 denotes (C.sub.1 -C.sub.4) alkoxy, NH.sub.2, hydroxyl, NR.sup.1 R.sup.2, unsubstituted or mono or Poly substituted benzyloxy, wherein the substituent is a member of the group-consisting of halogen, nitro, NH.sub.2 (C.sub.1 -C.sub.4),alkyl, (C.sub.1 -C.sub.4) and one or more units of the formula II ##STR8##whereincompounds of formula III or a salt form thereof, ##STR9##whereinR.sup.1, R.sup.2 and R.sup.3 have the above-mentioned meaning andR.sup.4 denotes hydrogen are reacted with a carbamoylase to remove the carbamoyl protective group.