Patent ID: 6638954
Filing Date: 2003-10-28
Classification: A61K,C07D

Abstract:
A non-neurotoxic antiischemic composition for the treatment of stroke in mammals, comprising as the active ingredient, an effective amount comprising from about 0.01 to about 99 wt. % of an antiischemic &Dgr;2-1,2,3-triazoline compound, selected from the compounds of the formulae, wherein R2 is 4-pyridyl, 3-pyridyl, or 2-pyridyl and R1 is 3,4- or 3,5-dichloro, p- or m-chloro, p- or m-bromo, p- or m-fluoro, p- or m-trifluoromethyl, p- or m-lower alkyl, p- or m-lower alkoxy or hydrogen, and a pharmaceutical carrier.