Patent ID: 8597717
Filing Date: 2013-12-03
Classification: A61L,B05D,C08J,C08L

Abstract:
1. A method of making an oriented collagen gel, comprising the step of depositing with a depositing device a concentration of collagen onto a substrate to induce fibrillogenesis, wherein said depositing device having a depositing speed during said deposition and wherein said concentration of collagen having a travelling speed while being deposited, wherein said depositing speed and travelling speed are both larger than zero, but moving in opposite direction from each other and together defining a draw ratio of said depositing speed and said travelling speed for said deposition of said concentration of collagen, wherein said depositing step applies both a shear and an extensional force component to said concentration of collagen during said fibrillogenosis, and while said deposition occurs in a pH buffer of at least 5.