Patent ID: 6818750
Filing Date: 2004-11-16
Classification: A01K,A61K,A61P,C07K

Abstract:
An isolated nucleic acid molecule encoding a NB-ARC and CARD containing protein (NAC), comprising a nucleotide sequence encoding a polypeptide having at least 80% identity to SEQ ID NO:4 or SEQ ID NO:6, or the complement of said nucleotide sequence,wherein said polypeptide forms a CARD domain fold, wherein said polypeptide comprises an NB-ARC domain capable of associating with the NB-ARC domain of SEQ ID NO:2, wherein said polypeptide does not comprise amino acids 957-987 of SEQ ID NO:2, and wherein said polypeptide associates with SEQ ID NO:2 or with Apaf-1.