Patent ID: 8383584
Filing Date: 2013-02-26
Classification: A61P,C07D

Abstract:
1. A compound of the formula (I): wherein A is —C(═O)OR wherein; R R R R R R X is N, CH and when X bears a double bond it is C; E is NR R R n is 3, 4, 5 or 6; each dotted line - - - independently represents an optional double bond; R R R each R each R each aryl independently is phenyl optionally substituted with one, two or three substituents selected from halo, hydroxy, nitro, cyano, carboxyl, C each Het independently is a 5 or 6 membered saturated, partially unsaturated or completely unsaturated heterocyclic ring containing 1, 2, 3 or 4 heteroatoms each independently selected from nitrogen, oxygen and sulfur, said heterocyclic ring being optionally substituted with one, two or three substituents each independently selected from halo, hydroxy, nitro, cyano, carboxyl, C each Het or an N-oxide, a stereoisomer, a pharmaceutically acceptable addition salt, or pharmaceutically acceptable solvate thereof.