Patent ID: 8741903
Filing Date: 2014-06-03
Classification: A61K,A61P

Abstract:
1. A method of treating humans suffering from hepatocellular carcinoma (HCC) which comprises administering to said human in need of such treatment a dose of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one or a tautomer thereof, or a pharmaceutically acceptable salt or a hydrate or a solvate thereof wherein 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one or a tautomer thereof or a pharmaceutically acceptable salt or a hydrate or a solvate thereof is used as the sole active ingredient, wherein the weekly dose consists of a daily dose administration of 500 mg for 5 days and no administration for two days.