Patent ID: 7906150
Filing Date: 2011-03-15
Classification: A61K,A61P,C07K

Abstract:
1. A method for treating a hypertensive condition related to excessive parathyroid hypertensive factor comprising: administering to a mammalian patient in need of such treatment, an effective amount of a shark cartilage extract having anti-parathyroid hypertensive factor activity, said amount effective to decrease blood pressure in said patient, and wherein the shark cartilage extract is produced by the following steps: extracting cleaned, dried, ground shark cartilage with H centrifuging the cooled first suspension at between 5200 to 5700 rpm to separate the first suspension into a first supernatant and a pellet, holding the first supernatant in a cooling tank at 4-8° C., extracting said pellet with H2O at a temperature between 85-120° C. for 2-4 hours to provide a second suspension and cooling the second suspension to between 40-60° C., centrifuging the second suspension at between 5200-5700 rpm to separate the second suspension into a second supernatant and a pellet, pooling the first supernatant with the second supernatant to provide pooled supernatants, and spray drying the pooled supernatants to obtain the shark cartilage extract.