Patent ID: 7754678
Filing Date: 2010-07-13
Classification: A61P,C07K,C12N

Abstract:
1. A fusion protein for delivery of an organic molecule into a cell comprising a membrane penetrating peptide attached to said organic molecule, wherein the membrane penetrating peptide is not full length human Period 1 protein or full length human Period 3 protein, said membrane penetrating peptide comprising a peptide selected from the group consisting of the peptides: RRHHCRSKAKRSRHH (SEQ ID NO:56), SRRHHCRSKAKRSRHH (SEQ ID NO: 16), SARHHCRSKAKRSRHH (SEQ ID NO:40), SRAHHCRSKAKRSRHH (SEQ ID NO:41), SRRAHCRSKAKRSRHH (SEQ ID NO:42), SRRHACRSKAKRSRHH (SEQ ID NO:43), SRRHHARSKAKRSRHH (SEQ ID NO:44), SRRHHCRAKAKRSRHH (SEQ ID NO:46), SRRHHCRSAAKRSRHH (SEQ ID NO:47), SRRHHCRSKAARSRHH (SEQ ID NO:48), SRRHHCRSKAKASRHH (SEQ ID NO:49), SRRHHCRSKAKRARHH (SEQ ID NO:50), SRRHHCRSKAKRSAHH (SEQ ID NO:51) and RRHHCRSKAKRSR (SEQ ID NO:52) and RKGKHKRKKLP (SEQ ID NO:55).