Patent ID: 8697378
Filing Date: 2014-04-15
Classification: C12Q,G01N

Abstract:
1. A method for quantitatively determining small, dense LDL cholesterol, comprising: adding enzymes for cholesterol measurement to a test sample in the presence of a polyoxyethylene-polyoxypropylene copolymer represented by formula (II): wherein a is an integer between 1 and 200, b is an integer between 1 and 200, c is an integer between 1 and 200, d is an integer between 1 and 60, e is an integer between 20 and 100, and f is an integer between 1 and 60, wherein R denotes a hydrogen atom or linear or branched alkyl having a carbon number ranging from C1 to C30; (ii) causing the polyoxyethylene-polyoxypropylene copolymer to selectively act on small, dense LDLs among lipoproteins, and then (iii) measuring the amount of cholesterol generated.