Patent ID: 8343459
Filing Date: 2013-01-01
Classification: A61K,C07B,C07C

Abstract:
1. A method for producing a radioactive diagnostic imaging agent containing a radioactive 18 fluorine-labeled organic compound represented by the following formula (1): which comprises a first step of providing a solution containing the radioactive a second step of adding an acid to the solution obtained in the first step in an amount sufficient for the solution to be kept within a pH of 2.0-5.9 in the following third step, and a third step of diluting the solution obtained in the second step in order to adjust the solution to a desired radioactive concentration within a pH of 2.0-5.9, wherein the second step comprises not only adding an acid, but also adding a sugar or sugar alcohol in an amount that meets a concentration of not less than 0.5 mmol/L in the solution in the third step, and/or, the third step comprises not only adding a liquid for dilution, but also adding a sugar or sugar alcohol in an amount that meets a concentration of not less than 0.5 mmol/L in the solution in the third step.