Patent ID: 8524913
Filing Date: 2013-09-03
Classification: C07B,C07C,C07D

Abstract:
1. A process of producing a α-trifluoromethyl-β-substituted-β-amino acid represented by formula [4] comprising: allowing a α-trifluoromethyl-β-substituted-α,β-unsaturated ester represented by formula [1] to react with a hydroxylamine represented by formula [2] to convert the α-trifluoromethyl-β-substituted-α,β-unsaturated ester into a dehydrogenated closed-ring body of the α-trifluoromethyl-β-substituted-β-amino acid represented by formula [3] to react with a hydroxylamine represented by formula [2] to convert the α-trifluoromethyl-β-substituted-α,β-unsaturated ester into a dehydrogenated closed-ring body of the α-trifluoromethyl-β-substituted-β-amino acid represented by formula [6] and hydrogenolyzing the dehydrogenated closed-ring body, wherein, in the formulae, and hydrogenolyzing the dehydrogenated closed-ring body, wherein, in the formulae,