Patent ID: 7553665
Filing Date: 2009-06-30
Classification: A61P,C07K,C12N

Abstract:
1. A process for the cultivation of cells producing interleukin-18 binding protein (IL-18BP) or the production of IL-18BP comprising cultivating a cell expressing IL-18BP in a cell culture medium that is free of components derived from animal serum, wherein the cell culture medium comprises: Asparagine at a concentration ranging from about 800 to about 900 mg/L; Natrium Chloride at a concentration ranging from about 3000 to about 4500 mg/L; Selenite at a concentration ranging from about 0.005 to about 0.015 mg/L; Wheat hydrolysate at a concentration ranging from about 5000 to about 15000 mg/L; and Insulin at a concentration ranging from about 2.5 to about 6 mg/L.