Patent ID: 8399010
Filing Date: 2013-03-19
Classification: A61K,A61L,A61P

Abstract:
1. A method for inducing bone growth in a primate, comprising: (a) providing an osteogenic sponge composition comprising: a resorbable sponge matrix material comprising collagen; an osteogenic factor that stimulates osteoblasts and osteoclasts, said osteogenic factor incorporated in said sponge matrix material in an amount that causes an increased rate of resorption of said sponge matrix material in the primate; and a particulate mineral having an average particle diameter of at least about 0.5 mm embedded in said resorbable sponge matrix material, the sponge matrix being three-dimensionally stable but flexible and comprising 95% to 99% by weight of said particulate mineral so as to provide a scaffold for bone ingrowth in the presence of said ostegenic factor; and (b) implanting said osteogenic sponge composition in an area in which bone growth is desired in the primate, said osteogenic sponge composition providing a scaffold for a duration sufficient for osteoid ingrowth through an area in which said osteogenic sponge composition is implanted.