Patent ID: 8629123
Filing Date: 2014-01-14
Classification: A61K,A61L,A61P

Abstract:
1. A method of inhibiting Instant Blood-Mediated Inflammatory Reaction (IBMIR) in a patient, comprising administering a therapeutically effective amount of dextran sulfate, or a pharmaceutically acceptable salt thereof, to a patient in need of such treatment, wherein the dextran sulfate, or the pharmaceutically acceptable salt thereof, is administered to the patient (i) prior to transplantation of a cell transplant to the patient, or (ii) together, in a solution, with the cell transplant, or (iii) both prior to transplantation of the cell transplant to the patient and together, in a solution, with the cell transplant, wherein the dextran sulfate, or the pharmaceutically acceptable salt thereof, has an average molecular weight of less than 20,000 Da.