Patent ID: 7101714
Filing Date: 2006-09-05
Classification: C07K,C12Q

Abstract:
1. A method for identifying a compound that modulates the activity of a polypeptide comprising the CARD domain of CARD-4, the method comprising: (a) providing a sample comprising a cell expressing a recombinant polypeptide comprising an amino acid sequence selected from the group consisting of: (b) exposing the sample to a test compound; (c) measuring the activity of the recombinant polypeptide or a CARD4 mediated cellular response in the test sample exposed to the test compound; and (d) determining that the test compound is a candidate compound for the modulation of the activity of the recombinant polypeptide if the level of activity of the recombinant polypeptide or the cellular response in the sample exposed to the test compound differs from a predetermined value.