Patent ID: 6617344
Filing Date: 2003-09-09
Classification: A61P,C07D

Abstract:
A heterocyclically substituted benzoylguanidine of formula I in which:R(1) is â€”(CF2)câ€”CF3; c is zero, 1, 2 or 3; R(2) is benzimidazolyl, linked via C or N, which is unsubstituted or substituted by 1-3 substituents selected from the group consisting of F, Cl, CF3, CH3, methoxy, hydroxyl, amino, methylamino and dimethylamino; R(3) is H, F, Cl, Br, I, CN, NO2 or (C1-C8)-alkyl; R(4) is (C1-C4)-alkyl, (C1-C4)-alkoxy, F, Cl, Br, I, CN or â€”(CF2)oâ€”CF3; o is zero, 1 or 2; or a pharmaceutically tolerable salt thereof.