Patent ID: 8987273
Filing Date: 2015-03-24
Classification: A61P,C07D

Abstract:
1. A compound of formula (I) wherein R1 is hydrogen, halogen, 2-6C-alkenylen-C(O)NH2, 2-6C-alkenylen-C(O)OR10, or a group selected from 1-6C-alkyl, 2-6C-alkenyl, 3-7C-cycloalkyl, aryl, heteroaryl, wherein said group being optionally substituted, one or more times, identically or differently, with a substituent selected from: R2 is hydrogen, halogen, cyano, or a group selected from 1-6C-alkyl, 3-7C-cycloalkyl, R3 is hydrogen, 1-6C-alkyl, 3-7C-cycloalkyl, R4 is phenyl optionally substituted, one or more times, identically or differently, with a substituent selected from: 1-6C-alkyl, halogen, cyano, R5 is hydrogen, halogen, R6 is hydrogen, 1-6C-alkyl, R8, R9 which can be the same or different, is hydrogen, 1-4C-alkyl or 3-7C-cycloalkyl, wherein said 1-4C-alkyl and 3-7C-cycloalkyl is optionally substituted in the same way of differently one or more times with halogen, hydroxy, mono- or di-1-4C-alkylamino, 1-4C-alkoxy, R10 is hydrogen, 1-6C-alkyl, R11 is 1-4C-alkyl (optionally substituted in the same way of differently one or more times with halogen, hydroxy) or 3-7C-cycloalkyl, X is —(CH n is 0, 1, 2, or 3, Y is —CH or an N-oxide, a salt, a tautomer or a stereoisomer of said compound, or a salt of said N-oxide, tautomer or stereoisomer.