Patent ID: 7217714
Filing Date: 2007-05-15
Classification: A61P,C07D

Abstract:
1. A compound of the formula or a pharmaceutically acceptable salt thereof, wherein [Region α] is a moiety of the formula wherein the symbol ‘*’ indicates the point of attachment of [Region α] to [Region β]; R R A is phenyl optionally substituted by up, to 4 substituents independently selected from fluoro, chloro, —CO p is 0, 1 or 2; R R R R R R [Region β] is an alkyl bridging element of partial formula wherein the symbol ‘*’ indicates the point of attachment of [Region β] to [Region α] and the symbol ‘→’ indicates the point of attachment of [Region β] to [Region γ]; R [Region γ] is piperidine being linked to [Region δ] through the ring nitrogen atom and each being linked to [Region δ] through any ring carbon atom, wherein said, piperidine is optionally substituted on a ring carbon atom by one substituent selected from C R [R egion δ] is a (substituted)-heterocyclyl moiety selected from the group consisting of: (i) a heterocyclyl moiety of partial Formula (5.3.0): wherein the symbol ‘*’ indicates the point of attachment of partial Formula (5.3.0) to [R egion γ] and wherein Q is N, O or S; and wherein partial Formula (5.3.0) is: is a member of the group consisting of triazoyl and oxadiazolyl, R j is 0, 1 or 2; HET R R wherein Q is N, O or S.