Patent ID: 6372508
Filing Date: 2002-04-16
Classification: G01N,Y10T

Abstract:
A method of measuring lipid peroxidation in a biological sample, in which the sample is heated to induce therein thermochemical luminescence (TCL) and in which said TCL is measured, said method comprising the steps of:a) providing a receptacle having a substantially flat bottom for receiving said sample; b) introducing said the sample into said receptacle; c) bringing said receptacle into contact with a heat sink member, said heat sink member is made of material having high thermal conductivity; d) imparting motion to said receptacle to distribute said sample over the bottom of said receptacle in a substantially homogeneous manner; e) drying said sample without causing freezing thereof by subjecting said sample to a reduced pressure and without adding heat for a period of time sufficient to remove the liquid from the sample and form a continuous layer of dry solid; f) heating said dry solid layer to a temperature sufficient for inducing TCL therein; and g) sensing said TCL and measuring thereof for a period of time sufficient for establishing a stable correlation between TCL intensity and time.