Patent ID: 9132089
Filing Date: 2015-09-15
Classification: A61K,A61P

Abstract:
1. A method of treating hypogonadism in a human male, the method comprising the steps of: applying, once per day, a therapeutically effective dose of a pharmaceutical composition to an area of skin of the human male, the pharmaceutical composition consisting of: (i) 0.1% to 10% (w/w) testosterone; (ii) 0.10% to 5.0% (w/w) isopropyl myristate; (iii) 30.0% to 98.0% (w/w) of ethanol, isopropanol or combinations thereof; (iv) 0.1% to 5.0% of a polyacrylic acid, wherein the polyacrylic acid is neutralized with sodium hydroxide; and (v) water; wherein the administration of the pharmaceutical composition is as a gel and not as part of a patch, and further wherein the administration once per day is sufficient for the testosterone to reach the bloodstream of the human male to achieve a steady state profile in which there is an increase in serum testosterone levels of the human male for a period of time of 4 hours or less before returning to an approximately constant level.