Patent ID: 6506911
Filing Date: 2003-01-14
Classification: A61P,C07D

Abstract:
An 8-oxo-4,8-dihydro-2-phenyl-4H[3,2-d]-m-dioxin of formula (IIb), whereinR3 is selected from the group consisting of hydrogen and C1-6 alkyl; R4 is selected from the group consisting of hydrogen, C1-6 alkyl, â€”CR6R6OR7, â€”CONHâ€”R5, â€”CONHCOR5 and â€”CON(CnH2n+1)2; R5 is selected from the group consisting of hydrogen and optionally hydroxy, alkoxy, aryloxy substituted C1-13 alkyl, aralkoxy substituted C1-13 alkyl, aryl and C7-13 aralkyl; R6 is independently selected at each occurrence from the group consisting of hydrogen, C1-13 alkyl, aryl and C7-13 aralkyl; R7 is selected from the group consisting of hydrogen, C1-13 alkyl, aryl and C7-13 aralkyl; (CnH2n+1)2 is selected from the group consisting of C1-6 alkyl; and R10 is selected from the group consisting of hydrogen and C1-13 alkyl; and excluding 6-hydroxy methyl-2-phenyl-pyrano[3,2-d]-1,3-dioxin-8(4H)-one.