Patent ID: 6495594
Filing Date: 2002-12-17
Classification: A61K,A61P,C07B,C07C,C07D

Abstract:
A method for inhibiting the growth of cancer cells, said method comprising administering to said cells an effective amount of a discodermolide analog selected from the group consisting of 2-desmethyldiscodermolide (II); 19-desaminocarbonyldiscodermolide (III); methyldiscodermolate (V); 3-deoxy-2&Dgr;-discodermolide (VI); 8,21,23-hexahydrodiscodermolide (XII); 7-deoxy-8,21,23-hexahydrodisco-dermolide (XIII); and derivatives of these compounds wherein said derivatives are not modified at the C-11 or C-17 positions.