Patent ID: 6610286
Filing Date: 2003-08-26
Classification: A61K,A61P,C07K,Y10S

Abstract:
A method for inhibiting Interleukin 20 (IL-20)â€”induced inflammation, comprising bringing into contact with IL-20 a soluble receptor (IL-20R) that binds to IL-20, wherein the IL-20 is comprised of the amino acid sequence of SEQ ID NO: 2, and wherein the soluble receptor is comprised of an extracellular domain of an IL-20RA subunit and an extracellular domain of an IL-20RB subunit, wherein the extracellular domain of the IL-20RA subunit is comprised of the amino acid sequence of SEQ ID NO: 63 and the extracellular domain of the IL-20RB subunit is comprised of the amino acid sequence of SEQ ID NO:59.