Patent ID: 9034854
Filing Date: 2015-05-19
Classification: A61K,A61P

Abstract:
1. A method of treating estrogen-sensitive tumours in a mammal in need thereof, said estrogen-sensitive tumours being selected from the group consisting of breast cancer, uterine cancer, ovarian cancer, endometriosis, and uterine fibroids, comprising orally administering to said mammal a therapeutically effective amount of an estrogenic component selected from the group consisting of: substances represented by the following formula in which formula R precursors capable of liberating a substance according to the aforementioned formula which precursors are derivatives of the present estrogen substances, wherein the hydrogen atom of at least one of the hydroxyl groups has been substituted by an acyl radical of a hydrocarbon carboxylic, sulfonic acid or sulfamic acid of 1-25 carbon atoms; tetrahydrofuranyl; tetrahydropyranyl; or a straight or branched chain glycosydic residue containing 1-20 glycosidic units per residue; and mixtures of one or more of the aforementioned substances and/or precursors; said method not comprising administration of a GnRH composition.