Patent ID: 6685617
Filing Date: 2004-02-03
Classification: C07D,C07K

Abstract:
A compound of the formula: whereinR1 is hydrogen or C1-3 alkyl; R2 is hydrogen or C1-6 alkyl; in addition, R1 and R2 may be attached to the same carbon atom and may form a carbocyclic ring of 5-8 atoms together with the carbon atom to which they are attached or be attached to the same atom and form a ring of 5-8 atoms of the formula: together with the carbon atom to which they are attached;R3 and Y represent a) R3 is C7-17 arylalkyl, (C1-6 alkyl)-OH, (C1-6 alkyl)-CO2â€”R11, (C1-6 alkyl)-CN, adamantyl, phenyl, or one of the following: and Y is â€”C(&boxH;O)â€”, orb) R3 is C1-6 alkyl, C7-17 arylalkyl, (C1-6 alkyl)-OH, (C1-6 alkyl)-CO2â€”R11, (C1-6 alkyl)-CN, adamantyl, phenyl, or one of the following: and Y is â€”C(&boxH;O)â€”, â€”SO2â€”, or â€”C(&boxH;O)N(R10)â€”;R4 is â€”OH, NH21 NHOH, or is of the formula R5 is a formula of the following: wherein R7 is hydrogen or Cl;R6 is N or CH; R8 is â€”NHâ€”Y1â€”, or â€”CONHâ€”; R10 is C1-6 alkyl, or (C1-6 alkyl)-OH, or hydrogen; R11 is hydrogen or CH3; W is (C1-6 alkyl); X is S; Y1 is â€”COâ€”, â€”C(&boxH;O)Oâ€”, â€”SO2â€”, or â€”C(&boxH;O)N(R10)â€”; Z is O, CH2, or Nâ€”R11; l is 1 or 2; m is 2; n is 0; o is 0 or 1; p is 0; and q is 0 or 1.