Patent ID: 7375075
Filing Date: 2008-05-20
Classification: C07K,C12N

Abstract:
1. An isolated polypeptide consisting of: (i) a (ii) a peptide fragment of (i), wherein said fragment has the amino acid sequence of SEQ ID NO:2 or SEQ ID NO:4 and inhibits tcf-driven luciferase activity in colon cancer cells, or (iii) a peptide fragment of (i) having at least 90% amino acid sequence identity to the amino acid sequence of SEQ ID NO:4 and inhibits tcf-driven luciferase activity in colon cancer cells, or (iv) a peptide having at least 90% amino acid sequence identity to the amino acid sequence of SEQ ID NO:5 and inhibits tcf-driven luciferase activity in colon cancer cells, or (v) a peptide fragment of (i) having at least 90% amino acid sequence identity to the amino acid sequence of SEQ ID NO:2 and inhibits tcf-driven luciferase activity in colon cancer cells, or (vi) a peptide fragment of (i) having at least 90% amino acid sequence identity to the amino acid sequence of SEQ ID NO:3 and inhibits tcf-driven luciferase activity in colon cancer cells.