Patent ID: 8921121
Filing Date: 2014-12-30
Classification: B01L,G01N,Y10T

Abstract:
1. A portable system for counting particles in a sample fluid, comprising: a microfluidic chip including a flow chamber with a trapping mechanism configured to capture and isolate target particles flowing therethrough, the trapping mechanism including a plurality of microfluidic channels with surface augmentations or a plurality of micro-trap arrays, and employing a hydrodynamic effect and an immobilizer for an antibody to capture and isolate the target particles, wherein the hydrodynamic effect is generated by establishing sample fluid flow through the plurality of microfluidic channels or micro-trap arrays using a pump connected to the flow chamber; an activating mechanism configured to apply a chemical activator on the trapped target particles, which activator is selected to cause a material conjugated to the target particles to generate chemiluminescent light emission from the trapped target particles, whereby light is generated without the use of a light source; a detecting device positioned adjacent said trapping mechanism and configured to detect chemiluminescent light emitted by said trapped target particles, the detecting device generating a signal based on the detected light; and a processing device configured to convert said signal to a target particle count.