Patent ID: 8771719
Filing Date: 2014-07-08
Classification: A61L,C08L

Abstract:
1. A composition, comprising: a plurality of bone particles having a surface modified with a silane coupling agent; wherein the bone particles are about 51% to about 75% by weight of the composition, or the bone particles are about 76% to about 99% by weight of the composition; and a polymer precursor selected from a monomer, and a prepolymer, wherein: when the polymer precursor is polymerized, at least a portion of the bone particles are covalently attached to the polymerized polymer precursor, at least a portion of the interstitial and vascular structure of the bone particles is infiltrated by the polymerized polymer precursor, or both and the composition comprises a polymer matrix having at least about 60% of the bone particles being elongated and randomly orientated in the polymer matrix and the polymer matrix comprises a biodegradable polyurethane.