Patent ID: 8932867
Filing Date: 2015-01-13
Classification: A61K,A61P,C08B,G01N,Y10T

Abstract:
1. A method for detecting or measuring a nitrous acid degradation-resistant mucopolysaccharide or a nitrous acid degradable mucopolysaccharide contained in a mucopolysaccharide, which comprises: i) degrading the mucopolysaccharide with nitrous acid at pH of 1.0 to 7.0, a reaction temperature of −10 to 40° C., a reaction time of 0.5 to 60 minutes, and an amount of 10 to 1000 mg of nitrous acid used to 1 g of the mucopolysaccharide; and ii) analyzing the degraded product of the step (i) by HPLC.