Patent ID: 8481280
Filing Date: 2013-07-09
Classification: A01N,A61K,C12Q

Abstract:
1. A method for determining a presence or absence of combined antibiotic activity of a first antibiotic and a hops composition against a target microorganism, comprising: providing the target microorganism in a carrier, said carrier being in the form of a solution, suspension or gel, contacting said target microorganism carrier with a discrete quantity of said first antibiotic for a period of time sufficient to create at the area of contact, a first zone of sensitivity of said target microorganism carrier sensitive to said first antibiotic, observing said first zone of sensitivity, dispersing a hops composition in said target microorganism carrier in an amount in which said microorganism will not exhibit sensitivity to create a hops-modified target microorganism carrier, contacting said hops-modified target microorganism carrier with said discrete quantity of said first antibiotic for a period of time sufficient to create at said area of contact, a second zone of sensitivity of said hops-modified target microorganism carrier sensitive to said first antibiotic, observing said second zone of sensitivity and comparing said first and second zones of sensitivity to determine whether said second zone is larger than said first zone and, therefore, whether the combined antibiotic activity of said first antibiotic and said hops composition against said target microorganism is greater than the antibiotic activity of said first antibiotic alone.