Patent ID: 6581441
Filing Date: 2003-06-24
Classification: B01J,G01N

Abstract:
A microfluidic circuit for separating components of a fluid sample comprising:a first capillary of first etched depth formed in a first region of the circuit adapted to receive the fluid sample; a second capillary of second etched depth larger than that of the first capillary formed in a second region of the circuit in fluid communication with the first capillary; a third capillary of third etched depth smaller than that of the second capillary formed in a third region of the circuit in fluid communication with the second capillary; a solid composition contained within the second capillary capable of effecting separation of the components of the sample; wherein the solid composition comprises solid particles and the etched depths of the first and third capillary are smaller than the size of the solid particles to retain the particles within a desired containment volume of the second capillary and being sufficiently large to permit passage of the fluid sample therethrough.