Patent ID: 7758872
Filing Date: 2010-07-20
Classification: A61K,A61P,C12Y

Abstract:
1. A method for treating major depression or dysthymia in a subject, the method comprising selecting a subject diagnosed with a disorder consisting of major depression or dysthymia using specific clinical criteria for major depression or dysthymia; and administering to the subject 30 to 50 unit equivalents of a Botulinum toxin to one or both of a corrugator supercilii muscle and a procerus muscle, to cause paralysis of one or both of the corrugator supercilii muscle and the procerus muscle; and wherein the subject is also treated with a therapeutically effective amount of a selective serotonin reuptake inhibitor (SSRI); thereby decreasing the ability of the subject to frown and treating the disorder consisting of major depression or dysthymia in the subject.