Patent ID: 6649172
Filing Date: 2003-11-18
Classification: A61P,C07C

Abstract:
A compound, having the formula: wherein, R is hydrogen or â€”C(O)H; R1 is a member selected from the group consisting of hydrogen, a substituted C1-20 saturated, unsaturated or cyclic alkyl, saturated or unsaturated heteroalkyl or saturated or unsaturated heterocycloalkyl group, an unsubstituted C1-20 saturated, unsaturated or cyclic alkyl, saturated or unsaturated heteroalkyl or saturated or unsaturated heterocycloalkyl group, a saccharyl group, and a group represented by the formula â€”C(O)â€”[C(R3)(R4)]nâ€”COOH,wherein each R3 and R4 independently is a member selected from the group consisting of hydrogen and a substituted C1-10 saturated, unsaturated or cyclic alkyl, saturated or unsaturated heteroalkyl or saturated or unsaturated heterocycloalkyl group, and an unsubstituted C1-10 saturated, unsaturated or cyclic alkyl, saturated or unsaturated heteroalkyl or saturated or unsaturated heterocycloalkyl group; and n is a number from 1 to 5; R2 is a member selected from the group consisting of hydrogen, a substituted C1-20 saturated unsaturated or cyclic alkyl, saturated or unsaturated heteroalkyl or saturated or unsaturated heterocycloalkyl group, an unsubstituted C1-20 saturated unsaturated or cyclic alkyl, saturated or unsaturated heteroalkyl or saturated or unsaturated heterocycloalkyl group, and a group represented by the formula â€”(CH2)mCH(OH)(CH2)pOR5, wherein m and p are independently 1 or 2, and R5 is a substituted C2-20 saturated, unsaturated or cyclic alkyl, saturated or unsaturated heteroalkyl or saturated or unsaturated heterocycloalkyl group, or an unsubstituted C2-20 saturated, unsaturated or cyclic alkyl, saturated or unsaturated heteroalkyl or saturated or unsaturated heterocycloalkyl group, or a group represented by the formula â€ƒwherein j is 1-5, and R6 and R7 are independently selected from the group consisting of hydrogen, a substituted C1-20 saturated, unsaturated or cyclic alkyl, saturated or unsaturated heteroalkyl or saturated or unsaturated heterocycloalkyl group, and an unsubstituted C1-20 saturated, unsaturated or cyclic alkyl, saturated or unsaturated heteroalkyl or saturated or unsaturated heterocycloalkyl group; or a pharmacologically acceptable salt thereof.