Patent ID: 7109189
Filing Date: 2006-09-19
Classification: A61K,A61P,C07D,C07F

Abstract:
1. A compound comprising a lipophilic cation moiety, wherein the lipophilic cation moiety is selected from the group consisting of: ammonium cations; phosphonium cations; arsonium cations; rhodamine 123; JC-1; N,N′-bis(2-ethyl-1,3-doxylene)kryptocyanine; pyronine Y; o-toluidine blue; chalcogenpyrilium; benzo(a)phenoxazinium and a tribenzyl or triphenyl substituted ammonium or phosphonium cation, covalently coupled to an antioxidant moiety which is a glutathione peroxidase mimetic, wherein the glutathione peroxidase mimetic moiety is selected from the group consisting of: benzisoselenazolones, diaryl diselenides and diaryl selenides.