Patent ID: 6403860
Filing Date: 2002-06-11
Classification: C07K,C12N

Abstract:
An isolated polynucleotide comprising a polynucleotide selected from the group consisting of:(a) a polynucleotide having at least 80% sequence identity, as determined by the GAP algorithm under default parameters, over the entire coding region, to the polynucleotide of SEQ ID NO: 1, wherein the polynucleotide encodes a polypeptide with Ku80 activity; (b) a polynucleotide encoding the polypeptide of SEQ ID NO: 2; (c) a polynucleotide which selectively hybridizes, under stringent hybridization conditions and a wash in 0.1Ã—SSC at 60Â° C., to the entire length of polynucleotide of SEQ ID NO: 1, wherein the complementary sequence of said polynucleotide encodes a polypeptide with Ku80 activity; (d) a polynucleotide of SEQ ID NO: 1; and (e) a polynucleotide which is fully complementary to the polynucleotide of (a), (b), (c), or (d).