Patent ID: 7034055
Filing Date: 2006-04-25
Classification: A61P,C07C,C07D

Abstract:
1. A compound having structural formula (I): stereoisomers thereof, or pharmaceutically acceptable salts or hydrates thereof, wherein: R1 and R2 are each separately selected from the group consisting of: X is an acidic group selected from the group consisting of carboxy, phosphono, phosphino, sulfono, sulfino, borono, tetrazol and isoxazol; Y is a basic group selected from the group consisting of 1° amino, 2° amino, 3° amino, quaternary ammonium salts, aliphatic 1° amino, aliphatic 2° amino, aliphatic 3° amino, aliphatic quatemary ammonium salts, aromatic 1° amino, aromatic 2° amino, aromatic 3° amino, aromatic quaternary ammonium salts, imidazol, guanidino, boronoamino, allyl, urea and thiourea; m is 0, 1; R3, R4, R5, R6 are independently H, nitro, amino, halogen, tritium, trifluoromethyl, trifluoroacetyl, sulfo, carboxy, carbamoyl, sulfamoyl, or an acceptable ester thereof; with the proviso that at least one of R1 and R2 is other than H.