Patent ID: 8435534
Filing Date: 2013-05-07
Classification: A61K,A61P,C07K

Abstract:
1. A method for stimulating an immune response against IL-13Rα2 in a subject having tumor cells expressing IL-13Rα2, the method comprising the steps of: (a) formulating an anti-cancer vaccine outside of the subject, the vaccine comprising an agent that can stimulate an immune response against IL-13Rα2 when administered to an animal, wherein the agent that can stimulate an immune response against IL-13Rα2 is a protein comprising the amino acid sequence of SEQ ID NO:1 or a protein fragment thereof; and (b) administering the vaccine to the subject in an amount sufficient to stimulate an immune response against IL-13Rα2 and inhibit growth of the tumor cells in the subject; and (c) measuring stimulation of the immune response against IL-13Rα2 in the subject having tumor cells expressing IL-13Rα2.