Patent ID: 8303533
Filing Date: 2012-11-06
Classification: A61B,A61M

Abstract:
1. A device for delivery of a physiologically active substance depending on a measured physiological parameter, the device comprising: a container for a perfusion fluid containing the physiologically active substance, a unit for delivery of the perfusion fluid containing the physiologically active substance into the body, a sensor for measuring the physiological parameter of the body by an analysis of the perfusion fluid after an at least partial equilibration of the perfusion fluid with a body fluid, a unit, which is connected to the sensor by a signal line, for controlling the quantity of the physiologically active substance to be delivered depending on the measured physiological parameter, a unit for calibrating the measurement of the physiological parameter, wherein the sensor for measuring the physiological parameter is combined with the unit for delivery of the perfusion fluid containing the physiologically active substance in such a way that a location of the measurement of the body fluid for determining the physiological parameter in the body is in an area of influence of the delivered physiologically active substance, so that the measurement of the physiological parameter occurs essentially at the location of the delivery of the physiologically active substance, and wherein the unit for calibrating the measurement of the physiological parameter is formed by a unit for measuring the conductivity of the perfusion fluid after an at least partial equilibration of the perfusion fluid with the body fluid.