Patent ID: 6420557
Filing Date: 2002-07-16
Classification: A61K,C07D

Abstract:
A polymorph of 1-{6-ethoxy-5-[3-ethyl-6,7-dihydro-2-(2-methoxyethyl)-7-oxo-2H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-pyridylsulfonyl}-4-ethylpiperazine having a simulated powder X-ray diffraction pattern with main peaks substantially as defined below:d-spacingIntensity(Ã¥)(%)12.24681.249.73011008.559636.317.392315.027.38568.357.32841.695.822214.495.76171.965.746143.255.11667.175.107832.714.880717.474.867410.854.86510.984.842513.194.80183.324.763210.574.74914.164.6411.964.62919.734.33149.534.33013.654.306626.664.290951.917.279824.754.232319.044.15951.194.04211.353.91867.813.895110.263.84915.343.84852.463.842743.143.73573.13.69613.993.68054.513.60425.283.59886.093.58196.83.57218.553.53552.473.4071.23.34614.913.33187.543.31544.363.28271.73.27741.223.243419.953.2242.113.06631.383.0619.183.04832.223.04281.942.99291.592.98042.12.94033.462.90731.742.87191.682.85324.72.812211.192.80972.822.77762.172.77741.462.71621.762.70413.632.68751.422.64432.192.60843.752.60251.62.58091.312.54481.212.54383.262.43252.472.42121.242.41634.392.40412.242.34241.222.2991.132.2641.232.26051.292.20792.652.18551.92.16791.922.14681.352.11194.522.07691.152.04711.122.0281.631.99351.031.98832.961.91811.271.90581.031.8841.231.87972.491.87492.811.79391.571.76171.241.73791.821.71941.03wherein said PXRD pattern is generated using copper K-alpha1 X-rays having a wavelength of 1.54178 Angstroms.