Patent ID: 7414729
Filing Date: 2008-08-19
Classification: A61B,G01N

Abstract:
1. A coherent anti-Stokes Raman scattering endoscopy system for detecting an anti-Stokes signal from a sample volume, said system comprising: a source system for providing a pulsed pump field at a first frequency and a pulsed Stokes field at a second frequency that is different from the first frequency, both said pulsed pump field and said pulsed Stokes field being provided at the same pulse repetition rate and synchronous with one another; and an optical fiber system including at least one optical fiber, said optical fiber system for guiding said pulsed pump and Stokes fields to the sample volume such that pump pulses and Stokes pulses arrive at the same time in the sample volume to generate third order non-linear coherent radiation characteristic of molecular vibrations by non-linear interaction of the pulsed pump and Stokes fields with the sample volume, for receiving the anti-Stokes signal resulting from the coherent radiation, and for guiding the anti-Stokes signal to a detector, wherein said pulsed pump and Stokes fields are collinearly directed to said sample volume in a single beam that includes said pulsed pump and Stokes fields.