Patent ID: 6228373
Filing Date: 2001-05-08
Classification: A61K,A61P,C07K

Abstract:
A peptide dimer comprising a first and a second peptide monomer, each monomer conforming to Formula (I):(A).sub.n --X--Cys--Cys--Y--(B).sub.m (I)whereineach A is independently selected from the group consisting of an H, a protecting group, and a glycine, proline, or cysteine amino acid residue, wherein an amino acid residue at position ""A"" is in either an L- or a D-form;n is the integer one or the integer two;X is NH or a glycine or proline amino acid residue;Y is NH or a glycine or proline amino acid residue;each B is independently selected from the group consisting of an H, an OH, an NH.sub.2, a protecting group, and a glycine, proline, or cysteine amino acid residue; andm is the integer one or the integer two;with the provisos that when A is not at least one amino acid residue, n is 1; when B is not at least one amino acid residue, m is 1; each peptide monomer contains no more than 6 amino acid residues; and the peptide dimer stimulates or inhibits an immune response in a mammal.