Patent ID: 6294572
Filing Date: 2001-09-25
Classification: A61P,C07D

Abstract:
5-Acetamido-2,3,4,5-tetradeoxy-4-guanidino-D-glycero-D-galacto-non-2-enopy ranoasonic acid in crystalline hydrate form, wherein the crystals have a low aspect ratio and an X-ray diffraction trace having the line intensities at the indicated d-spacings essentially as shown:d(A) I(%) 10.06 30.25 6.77 69.81 6.63 89.61 6.35 12.69 6.05 54.56 5.38 25.11 5.05 98.58 4.61 12.58 4.42 100.00 4.31 8.28 4.17 11.67 3.98 75.00 3.90 52.61 3.77 20.33 3.69 36.17 3.48 26.53 3.41 53.25 3.37 17.61 3.16 18.39 3.02 31.08 2.98 9.25 2.92 6.28 2.87 13.58 2.82 10.78 2.78 6.78 2.74 18.03 2.69 15.33 2.65 6.25 2.63 6.44 2.59 11.44 2.49 14.31 2.45 18.81 2.41 8.64 2.35 11.36 2.19 5.42 2.13 12.25 2.11 6.56 2.02 8.33 1.98 5.47,or wherein the crystals have a high aspect ratio and an X-ray diffraction trace having the line intensities at the indicated d-spacings essentially as shown:d(A) I(%) 16.88 66.34 10.38 50.60 9.50 16.08 8.47 40.46 7.12 100.00 5.84 11.78 5.33 18.83 5.21 33.99 4.78 12.94 4.57 75.81 4.32 16.37 4.25 18.49 4.14 43.26 3.96 10.33 3.76 22.11 3.64 25.16 3.57 37.04 3.52 15.69 3.40 16.85 3.34 21.20 3.17 13.52 3.13 17.04 3.06 7.48 2.94 10.19 2.92 8.45 2.86 9.17 2.76 9.56 2.72 9.22 2.67 6.81 2.64 8.06 2.60 5.46 2.58 6.52 2.51 5.31 2.49 6.66 2.45 5.55 2.43 5.89 2.39 15.93 2.38 10.38 2.31 8.40 2.22 5.94 2.16 5.36 2.11 6.28 2.03 7.24 1.91 6.57.