Patent ID: 6699503
Filing Date: 2004-03-02
Classification: A61K

Abstract:
A hydrogel-forming sustained-release oral preparation having a gelation index of 70% or more, which comprises:(1) a drug, wherein the amount of said drug is not more than 85% by weight based on the total preparation, (2) a polyethylene glycol which has a solubility such that the volume of water required for dissolving 1 gram of said polyethylene glycol is not more than 5 ml, and wherein the amount of said polyethylene glycol is from 5 to 80% by weight based on the total preparation, and (3) a hydrogel-forming polymer having a viscosity of not less than 1000 cps as measured at 1% concentration in water at 25Â° C., wherein the amount of said hydrogel-forming polymer is from 10 to 95% by weight based on the total preparation and not less than 70 mg per one preparation.