Patent ID: 8193485
Filing Date: 2012-06-05
Classification: G01N,G16B,H01J

Abstract:
1. A method for identifying proteins in a mixture comprising: receiving a first set of mass and retention time information associated with precursors and a second set of mass and retention time information associated with fragments of the precursors, wherein said first set of mass and retention time information and said second set of mass and retention time information are obtained from an LC/MS experiment using the mixture; selecting a target peptide; determining, for the target peptide, a target precursor and corresponding Y and B fragment ions of the target precursor, wherein the target precursor and said corresponding Y and B fragment ions of the target precursor have associated masses; determining mass matches for a substantially same retention time in said first set of mass and retention time information and said second set of mass and retention time information in accordance with the masses of said target precursor and said corresponding Y and B fragment ions of the target precursor; and identifying, in accordance with said mass matches for a substantially same retention time, whether the target peptide is present in the mixture.