Patent ID: 8999331
Filing Date: 2015-04-07
Classification: A61K,A61P,C07K

Abstract:
1. A binding protein comprising an antigen binding domain capable of binding human sclerostin, the antigen binding domain comprising three CDRs in a heavy chain and three CDRs in a light chain, wherein the heavy chain comprises a CDR-H1, a CDR-H2 and a CDR-H3; wherein the CDR-H1 comprises the amino acid sequence of X wherein the CDR-H2 comprises the amino acid sequence of G-X the CDR-H3 comprises the amino acid sequence of X wherein the light chain comprises a CDR-L1, a CDR-L2 and a CDR-L3; wherein the CDR-L1 comprises an amino acid sequence of G-S-S-T-G-X wherein the CDR-L2 comprises the amino acid sequence of D-T-X wherein the CDR-L3 comprises the amino acid sequence of L-L-X