Patent ID: 7049271
Filing Date: 2006-05-23
Classification: C07C,C07D

Abstract:
1. A process for preparing a compound of formula (I), wherein K represents oxygen or sulphur, Ar represents Ar X represents —CN, —CO—NH Y represents hydrogen, in each case optionally mono- or poly-hydroxy-substituted C Z represents hydrogen, methyl, ethyl, represents phenyl or benzyl, each of which is optionally mono- or disubstituted by fluorine, chlorine, bromine, methyl, methoxy, trifluoromethyl, trifluoromethoxy, cyano or nitro, wherein the process comprises: (A) if K represents oxygen, optionally in the presence of a diluent and optionally in the presence of a base or a metal compound of the formula (IVa)  in which (B) if K represents oxygen, optionally in the presence of a diluent to give a compound of the formula (VII)  in which which is reacted further, optionally in the presence of a base and optionally in the presence of a trivalent phosphorus compound, with elimination of sulphur and hydrogen halide, to give a compound of the formula (I) or that (C) a compound of the formula (II)  is initially condensed with a compound of the formula (VIII)  in which (D) if K represents sulphur, (E) if Ar represents Ar in the presence of a solvent, optionally in the presence of a base and/or a palladium metal complex.