Patent ID: 8945618
Filing Date: 2015-02-03
Classification: A61J,A61K

Abstract:
1. A method of producing an intrabuccally rapidly disintegrating tablet, said intrabuccally rapidly disintegrating tablet comprising: a sugar alcohol or saccharide in the form of primary particles having an average particle size of not more than 30 μm; an active ingredient; and one or more disintegrants selected from the group consisting of crosspovidone, crosscarmellose sodium, low substituted hydroxypropylcellulose, and a mixture thereof, said method comprising the steps of: (a) mixing a powder material comprising the sugar alcohol or saccharide, said active ingredient and said one or more disintegrants; (b) granulating the mixture of step (a), thereby producing granulated material having a predetermined particle size; and (c) compressing the granulated mixture into an intrabuccally rapidly disintegrating tablet.