Patent ID: 6977248
Filing Date: 2005-12-20
Classification: A61K,C12Q

Abstract:
1. A pharmaceutical preparation for inhibiting herpes simplex virus type-1 (HSV-1) infection in a mammal comprising a substantially pure heparan sulfate polysaccharide preparation enriched to comprise at least 5% for 3-O-sulfated glucosamine residues, wherein said substantially pure heparan sulfate polysaccharide preparation enriched for 3-O-sulfated glucosamine residues is obtained by the process comprising the step of contacting a heparan sulfate polysaccharide with a 3-OST-3 enzyme and a sulfate donor so as to produce a substantially pure heparan sulfate polysaccharide preparation enriched for 3-O-sulfated glucosamine residues.