Patent ID: 6835739
Filing Date: 2004-12-28
Classification: A61K,A61P,C07C,C07D

Abstract:
A compound having the formula:â€ƒwherein:A-Q is a member selected from the group consisting of: â€ƒR1a is a member selected from the group of H, F, Cl and Br; R1e is a member selected from the group consisting of â€”H, â€”F, â€”Cl, â€”Br, â€”OMe, â€”OH, â€”Me, â€”CF3 and â€”CH2NH2; R1d1, R1d2 and R1d4 are each H; R1d3 is selected from the group consisting of: H, â€”Me, â€”F, â€”Cl, â€”Br, aryl, heteroaryl, â€”NH2, â€”NMe2, â€”NHMe, â€”NHSO2NMe, â€”NHCOMe, â€”CF3, â€”OH, â€”OCH3, â€”SCH3, â€”OCF3, â€”OCH2F, â€”OCHF2,â€”OCH2CF3, â€”OCF2CF3, â€”NO2, â€”CN, â€”CO2H, â€”CO2Me, â€”CO2Et, â€”CONH2, â€”CONHMe, â€”CONMe2, â€”SO2NH2, â€”SO2CH3, â€”SO2NMe2, â€”CH2OH, â€”CH2NH2, â€”CH2NHMe, â€”CH2NMe2, â€”OCH2CO2H, â€”OCH2CO2Me, â€”OCH2CO2Et, â€”OCH2CONH2, â€”OCH2CONMe2, â€”OCH2CONHMe, â€”OCH2CH2OMe, â€”OCH2CH2OEt, â€”OCH2CH2NH2, â€”OCH2CH2NHMe, â€”OCH2CH2NMe2, â€”NHCH2CH2OMe, â€”SCH2CH2OMe, â€”SO2CH2CH2OMe, â€”OCH2CH2SO2Me, â€”NHCH2CH2NHMe, â€”NHCH2CH2NMe2, â€”N(CH2CH2OH)2, â€”N(CH2CH2OMe)2, â€”NHCH2CO2H, â€”NHCH2CO2Et, â€”NHCH2CO2Et, â€”NHCH2CONH2, â€”NHCH2CONMe2, â€”NHCH2CONHMe, â€”N(CH3)CH2CO2H, â€”N(CH3)CH2CO2Et, â€”(NMe)CH2COOH, â€”N(Me)CH2CONH2, â€”N(Me)CH2CH2NMe2, â€”N(Me)CH2CH2OMe, â€”NHCH2CH2OMe, â€ƒand all pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives thereof.