Patent ID: 7264723
Filing Date: 2007-09-04
Classification: B01D,B01F,B01L,G01N,Y10T

Abstract:
1. A dialysis system, comprising: a fluid microchannel comprising a depth, a width, and one or more interior surfaces, said interior surfaces being treated with a mixture consisting of water, glacial acetic acid and 3-(trimethoxysilylpropyl) acrylate to produce a coating comprising exposed acrylate groups and silane covalently bonded to said interior surfaces; a semipermeable polymer membrane comprising a monomer/cross-linker/solvent solution comprising (i) a monomer selected from the group consisting of alkyl-acrylates, polyfunctional acrylates, and zwitterionic molecules, (ii) a cross-linker material selected from the group consisting of polyfunctional acrylates, polyfunctional methacrylates, and polyfunctional acrylamides, (iii) a solvent medium, and (iv) a photo-initiator, wherein the semipermeable polymer membrane is prepared by localized photo-initiated phase separation polymerization, wherein said semipermeable polymer membrane is covalently bonded to said exposed acrylate groups of said coating, wherein said semipermeable polymer membrane spans said fluid microchannel width and depth to divide said dialysis system into a first region and a second region.