Patent ID: 8889115
Filing Date: 2014-11-18
Classification: A61K,A61P,C08F,Y10S

Abstract:
1. A method for removing potassium from a patient in need thereof comprising administering a potassium-binding polymer in an oral dosage form to a patient having renal insufficiency, the patient being treated for the renal insufficiency with a potassium-sparing diuretic, an angiotensin-converting enzyme inhibitor, an angiotensin receptor blocker, a non-steroidal anti-inflammatory drug, heparin, or trimethoprim and the potassium-binding polymer comprising a crosslinked cation exchange polymer in a bead form, wherein the potassium-binding polymer comprises a crosslinked cation exchange polymer comprising acid groups in their acid or salt form, the acid groups having an electron-withdrawing substituent attached to a carbon atom alpha or beta to the acid group.