Patent ID: 7767224
Filing Date: 2010-08-03
Classification: A61K,A61L,C09J

Abstract:
1. A process for a solvent-free and mastication-free production of a self-adhesive SBC-based composition which comprises at least one pharmaceutically active substance, in a continuously operating apparatus which comprises a feeding section and a compounding section, said process comprising (a) feeding an initial batch which comprises SBC, at least a part of the at least one pharmaceutically active substance and, optionally, at least a part of any further components of the composition into the feeding section of the apparatus; (b) transferring the initial batch from the feeding section to the compounding section of the apparatus; (c) optionally, adding any remaining part of the at least one pharmaceutically active substance and any remaining part of the further components of the composition which have not been added to the feeding section, to the compounding section; (d) treating the composition in the compounding section to prepare a homogeneous self-adhesive composition; and (e) discharging the homogeneous self-adhesive composition from the apparatus; a temperature inside the apparatus being not higher than 110° C.