Patent ID: 6607915
Filing Date: 2003-08-19
Classification: A61K,C12N,Y02P

Abstract:
An antisense compound 8 to 30 nucleobases in length targeted to nucleobases 1 through 20 of a 5â€² untranslated region, nucleobases 23 through 42 of a start codon region, nucleobases 176-195, or nucleobases 699 through 718 of a nucleic acid molecule encoding E2 A-Pbx1 of SEQ ID NO: 1, or nucleobases 376 through 395, nucleobases 1105 through 1124, or nucleobases 1594 through 1613 of a coding region, or nucleobases 1725 through 1744, nucleobases 1816 through 1835, or nucleobases 1955 through 1974 of a 3â€²-untranslated region of a nucleic acid encoding E2A-Pbx1 of SEQ ID NO: 2, wherein said antisense compound specifically hybridizes with one of said regions and inhibits the expression of E2A-Pbx1.