Patent ID: 8652516
Filing Date: 2014-02-18
Classification: A61K

Abstract:
1. A pharmaceutical composition in unit dose form for orally delivering doxycycline to a human, the pharmaceutical composition comprising: a capsule, wherein the capsule is coated with a delayed release layer; wherein the capsule does not contain an active ingredient; wherein the delayed release layer comprises about 4 to 6 mg of doxycycline, or a pharmaceutically acceptable salt thereof, and a binding agent, and wherein the delayed release layer is coated with an enteric coating; wherein the enteric coating dissolves at pH of about 5 to 6, and wherein the enteric coating is coated with an immediate release layer; wherein the immediate release layer comprises about 32 mg of doxycycline, or a pharmaceutically acceptable salt thereof, and a binding agent, wherein the relative mean C