Patent ID: 8093363
Filing Date: 2012-01-10
Classification: A61K,A61P,C07K,Y02A,Y10S

Abstract:
1. An isolated antibody or fragment thereof that specifically binds to a protein selected from the group consisting of: (a) a protein whose amino acid sequence consists of amino acid residues −27 to 147 of SEQ ID NO:2; (b) a protein whose amino acid sequence consists of amino acid residues −26 to 147 of SEQ ID NO:2; (c) a protein whose amino acid sequence consists of amino acid residues 1 to 147 of SEQ ID NO:2; (d) a protein whose amino acid sequence consists of amino acid residues 25 to 147 of SEQ ID NO:2; (e) a protein whose amino acid sequence consists of a portion of SEQ ID NO:2, wherein said portion is at least 30 contiguous amino acid residues in length; (f) a protein whose amino acid sequence consists of a portion of SEQ ID NO:2, wherein said portion is at least 50 contiguous amino acid residues in length; (g) a protein whose sequence consists of the amino acid sequence of the full-length polypeptide encoded by the cDNA contained in ATCC™ Deposit Number 75927; (h) a protein whose sequence consists of the amino acid sequence of the full-length polypeptide, excluding the N-terminal methionine residue, encoded by the cDNA contained in ATCC™ Deposit Number 75927; and (i) a protein whose sequence consists of the amino acid sequence of the extracellular domain of the polypeptide encoded by the cDNA contained in ATCC™ Deposit Number 75927.