Patent ID: 6200986
Filing Date: 2001-03-13
Classification: A61P,C07D

Abstract:
A compound of Formula (I) ##STR3##A.sup.1 and A.sup.2 are independently Z--(CH.sub.2).sub.k --(NR.sup.2).sub.y --;Z is independently a 4-10 membered mono- or bicyclic heterocyclic ring system containing up to four heteroatoms N, O, S in the ring in which at least one heteroatom is N, and wherein the ring is substituted or unsubstituted by one or two C.sub.1-4 alkyl, F, Cl, Br, I, C.sub.1-4 alkoxy, (CH.sub.2).sub.m R.sub.4, oxo, oxime, O-C.sub.1-4 alkyloxime, hydroxy, N(R.sub.3).sub.2, acylamino or aminoacyl groups, 8, 9, 10 membered monocyclic ring systems being excluded;R.sup.2 is independently hydrogen, C.sub.1-4 alkylC(O)R.sub.4, C.sub.1-4 alkyl or R.sub.2 is benzyl which is optionally substituted by one or two C.sub.1-4 alkyl, C.sub.1-4 alkoxy, F, Cl, I, Br, OH, or N(R.sub.3).sub.2 ;R.sub.3 is independently hydrogen, C.sub.1-4 alkyl, or benzyl;R.sub.4 is independently OR.sub.3, N(R.sub.3).sub.2 or SR.sub.3 ; andk is an integer from 0 to 4;m is 0;n is 1r is 1;s is 0;t is 2;y is zero or one;or a pharmaceutically acceptable salt thereof.