Patent ID: 6020492
Filing Date: 2000-02-01
Classification: A61P,C07D

Abstract:
A compound of the formula: ##STR41## or the pharmaceutically acceptable salts thereof wherein Ar is phenyl which is mono-, di-, or trisubstituted with halogen, hydroxy, lower alkyl, or lower alkoxy, with the proviso that at least one of the ortho positions of the Ar substituent is substituted;R.sub.3 and R.sub.4 are the same or different and representhydrogen or lower alkyl;cycloalkyl having 3-8 carbon atoms or cycloalkyl lower alkyl where the cycloalkyl portion has 3-8 carbon atoms; or2-hydroxyethyl or 3-hydroxypropyl optionally mono or disubstituted with lower alkyl with the proviso that not both R.sub.3 and R.sub.4 are hydrogen; andR.sub.5 is hydrogen or lower alkyl.