Patent ID: 6673534
Filing Date: 2004-01-06
Classification: A01K,A61K,C07K,C12N,C12Q

Abstract:
A method for detecting the presence of a target myostatin nucleic acid sequence in a nucleic acid-containing specimen from a subject having increased muscle mass or being screened for having a predisposition for increased muscle mass as compared to a subject having a wild-type nucleic acid sequence, said method comprising amplifying a target nucleotide sequence in the specimen with an oligonucleotide pair wherein one oligonucleotide hybridizes to SEQ ID NO:1 and one oligonucleotide hybridizes to SEQ ID NO:2, thereby amplifying the target nucleotide sequence; andanalyzing the amplified target myostatin nucleotide sequence for a mutation that is indicative of having increased muscle mass or having a predisposition for increased muscle mass as compared to a subject having a wild-type nucleic acid sequence.