Patent ID: 8442808
Filing Date: 2013-05-14
Classification: A61B,G01N

Abstract:
1. A method of guiding a human subject's physical training activity, comprising: a) measuring the concentration of each of two peptides, GGHPPPP (SEQ ID NO:1) and ESPSLIA (SEQ ID NO:2), in a saliva sample taken from the subject when the subject is in a rested state, wherein the subject is an adult athlete or an amateur athlete; b) identifying the subject's level of physical fatigue by calculating the ratio of the concentration of GGHPPPP (SEQ ID NO:1) to the concentration of ESPSLIA (SEQ ID NO:2) measured in (a) according to the equation: c) having the subject initiate or resume a physical training program comprising activities of different intensity; d) measuring the concentration of each of two peptides, GGHPPPP (SEQ ID NO:1) and ESPSLIA (SEQ ID NO:2), in a saliva sample taken from the subject at one or more time points after (c); e) identifying the subject's level of physical fatigue by calculating the ratio of the concentration of GGHPPPP (SEQ ID NO:1) to the concentration of ESPSLIA (SEQ ID NO:2) for each sample measured in (d) according to the equation: f) guiding the subject's physical training program by modifying the intensity of subsequent activities using the last of the subject's ratio(s), as calculated in (e), such that a decrease in the ratio relative to the previous ratio leads to a subsequent decrease in the subject's training intensity, an increase in the ratio relative to the previous ratio leads to a subsequent increase in the subject's training intensity, and a constant ratio relative to the previous ratio leads to a subsequent constant level in the subject's training intensity.