Patent ID: 9073801
Filing Date: 2015-07-07
Classification: B01J,C07B,C07D,C07F

Abstract:
1. A method comprising reacting a suitable diene with a stereogenic-at-metal catalyst or metal complex to form a compound of formula I: wherein the double bond depicted therein is in the cis configuration, and wherein: Ring A is an optionally substituted 8-30 membered saturated or partially unsaturated ring wherein 0-6 methylene units of Ring A are optionally and independently replaced by —O—, —N(R)—, —S—, —C(O)—, —OC(O)—, —C(O)O—, —OC(O)O—, —S(O)—, or —S(O) n is 0-20; each R is independently hydrogen or an optionally substituted group selected from C each R each Q is independently an optionally substituted bivalent C each —Cy wherein the catalyst or metal complex is of formula II-a: wherein: M is molybdenum or tungsten; R each of R R Ar is of the following formula: wherein: R R each R′ is independently hydrogen or an optionally substituted group selected from C or wherein the catalyst or metal complex is of formula II-b: wherein: M is molybdenum or tungsten; R R R Ar is of the following formula: wherein: R R each R′ is independently hydrogen or an optionally substituted group selected from C