Patent ID: 9120830
Filing Date: 2015-09-01
Classification: A61K,A61P,C07D,C07F

Abstract:
1. A method of treating a condition selected from the group consisting of prostate carcinoma, benign prostatic hyperplasia (BPH), hirsutism, alopecia, anorexia nervosa, breast cancer, acne, cachexia, diminished libido, male contraception, and male performance, comprising administering to subject in need thereof a therapeutically effective amount of a compound of formula (I) wherein R R wherein each R A and R B is independently selected from hydrogen or lower alkyl; R wherein the alkenyl or alkynyl is optionally substituted with one or more substituents independently selected from the group consisting of halogen, hydroxy, carboxy, cyano, nitro, NR wherein the aryl or heteroaryl, whether alone or as part of a substituent group is optionally substituted with one or more substituents independently selected from the group consisting of halogen, hydroxy, carboxy, lower alkyl, lower alkoxy, fluorinated lower alkyl, fluorinated lower alkoxy, phenoxy, cyano, nitro, NR R alternatively, R wherein the ring structure is optionally substituted with one or more substituents independently selected from the group consisting of lower alkyl, -(lower alkyl)-OH and -(lower alkyl)-(halogen); and pharmaceutically acceptable salts thereof.