Patent ID: 7056933
Filing Date: 2006-06-06
Classification: A61P,C07D

Abstract:
1. A compound wherein said compound is selected from the group consisting of: 5-Azepan-1-yl-1-(5-methanesulfonyl-pyridin-2-yl)-3-trifluoromethyl-1H-pyrazole-4-carbonitrile; 1-(5-Methanesulfonyl-pyridin-2-yl)-3-trifluoromethyl-5-(1,3,3-trimethyl-6-aza-bicyclo[3.2.1]oct-6-yl)-1H-pyrazole-4-carbonitrile; 5-Azepan-1-yl-3-difluoromethyl-1-(5-methanesulfonyl-pyridin-2-yl)-1H-pyrazole-4-carbonitrile; 5-Azocan-1-yl-1-(5-methanesulfonyl-pyridin-2-yl)-3-trifluoromethyl-1H-pyrazole-4-carbonitrile; 5-Azocan-1-yl-3-difluoromethyl-1-(5-methanesulfonyl-pyridin-2-yl)-1H-pyrazole-4-carbonitrile; 5-[1,4]Diazepan-1-yl-1-(5-methanesulfonyl-pyridin-2-yl)-3-trifluoromethyl-1H-pyrazole-4-carbonitrile; 5-(4-Acetyl-[1,4]diazepan-1-yl)-1-(5-methanesulfonyl-pyridin-2-yl)-3-trifluoromethyl-1H-pyrazole-4-carbonitrile; 1-(5-Methanesulfonyl-pyridin-2-yl)-5-(4-methyl-[1,4]diazepan-1-yl)-3-trifluoromethyl-1H-pyrazole-4-carbonitrile; 3-Difluoromethyl-1-(5-methanesulfonyl-pyridin-2-yl)-5-(4-methyl-[1,4]diazepan-1-yl)-1H-pyrazole-4-carbonitrile; 1-(5-Methanesulfonyl-pyridin-2-yl)-3-trifluoromethyl-5-(3,3,5-trimethyl-azepan-1-yl)-1H-pyrazole-4-carbonitrile; and 3-Difluoromethyl-1-(5-methanesulfonyl-pyridin-2-yl)-5-(3,3,5-trimethyl-azepan-1-yl)-1H-pyrazole-4-carbonitrile; or a pharmaceutically acceptable salt thereof.