Patent ID: 6087530
Filing Date: 2000-07-11
Classification: C07C,C07D,Y02P

Abstract:
A method for crystallizing preferentially an erythro-isomer of .alpha.-hydroxy-.beta.-amino compound presented by formula (2): ##STR17## wherein R.sup.1 represents a substituted or unsubstituted alkyl group containing 1 to 20 carbon atoms, a substituted or unsubstituted aralkyl group containing 7 to 30 carbon atoms, or a substituted or unsubstituted aryl group containing 6 to 30 carbon atoms; Q.sup.1 and Q.sup.2 each independently represents a hydrogen atom or an amino-protecting group or Q.sup.1 and Q.sup.2 combinedly represent a phthaloyl group with the proviso that Q.sup.1 and Q.sup.2 may not both be hydrogen,by using acetonitrile as solvent for the crystallization to eliminate the other stereoisomers.