Patent ID: 8986700
Filing Date: 2015-03-24
Classification: A61K,A61P,C07K,C12N

Abstract:
1. A lipopeptide comprising a polypeptide conjugated to one or more lipid moieties wherein: (i) said polypeptide comprises an amino acid sequence wherein the linkages between the amino acids making up the amino acid sequence consist of alpha-amino acid linkages and the amino acid sequence comprises: (ii) each of said one or more lipid moieties is covalently attached to an epsilon-amino group of said one or more internal lysine residues or to a terminal side-chain group of said one or more internal lysine analog residues, wherein an internal lysine residue or internal lysine analog residue to which a lipid moiety is attached is positioned in the polypeptide amino acid sequence between the Th epitope and the CTL epitope.