Patent ID: 7008765
Filing Date: 2006-03-07
Classification: A01K,A61K,A61P,C07K,C12Q

Abstract:
1. An isolated nucleic acid molecule comprising a polynucleotide sequence selected from the group consisting of: (a) a nucleotide sequence comprising the polynucleotide clone contained in the deposit at the Centraal voor Schimmelcultures as accession number CBS 682.97; (b) a nucleotide sequence comprising the polynucleotide clone contained in the deposit at the Centraal voor Schimmelcultures as accession number CBS 100521; (c) a nucleotide sequence comprising the nucleotide sequence set forth in SEQ ID NO:1, 3, 4 or 6, wherein said nucleotide sequence is over-expressed in prostate cancer tissue as compared to normal human tissues; (d) a nucleotide sequence fully complementary to any of the nucleotide sequences in (a), (b) or (c); and (e) a probe or primer that hybridizes under high stringency conditions to any of the nucleotide sequences in (a), (b), (c) or (d), said high stringency conditions comprising a hybridization at 68° C. in 5×SSC, 5× Denhardt's solution, 1% SDS, and 100 μg/ml denatured salmon sperm DNA, wherein said probe or primer does not hybridize to nucleotides 511–985 of SEQ ID NO:1, nucleotides 346–820 of SEQ ID NO:3, nucleotides 346–820 of SEQ ID NO:4, or nucleotides 533–1007 of SEQ ID NO:6, and wherein said probe or primer selectively hybridizes to polynucleotides over-expressed in prostate cancer tissue as compared to normal human tissues selected from the group consisting of: artery, brain, breast, duodenum, heart, liver, ovary, placenta, seminal vesicles, skeletal muscle, skin, spinal cord, spleen and testis.