Patent ID: 6953797
Filing Date: 2005-10-11
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A method of treating, or reducing the risk of, inflammatory disease in a person suffering from, or at risk of, said disease, wherein the method comprises administering to the person a therapeutically effective amount of a compound of formula (I), wherein: X and Y independently represent C1 to 4 alkyl, C1 to 4 alkoxy, halogen, CF m and p independently represent an integer 0, 1 or 2; Z represents H or fluoro; V represents S(O) W represents phenyl or a five or six membered aromatic heterocyclic ring containing 1 to 3 heteroatoms independently selected from O, S and N; said phenyl or aromatic heterocyclic ring being optionally substituted by one or more substituents selected independently from halogen, C1 to 4 alkyl, C1 to 4 alkoxy, OH, CN, NO R or the group NR R R R R n represents an integer 0, 1 or 2; or a pharmaceutically acceptable salt, enantiomer or racemate thereof, wherein the inflammatory disease is selected from the group consisting of inilammatory bowel disease, rheumatoid arthritis, osteoarthritis, chronic obstructive pulmonary disease and pain.