Patent ID: 8956566
Filing Date: 2015-02-17
Classification: A61L

Abstract:
1. A method for virus inactivation in the production, processing, storage or shipping of a biological or other sensitive substance comprising the steps of: dissolving carbon dioxide into a composition containing the biological or other sensitive substance, or otherwise exposing the biological or other sensitive substance to carbon dioxide, wherein the step of dissolving carbon dioxide into the composition further comprises sparginq carbon dioxide gas into the composition until the composition is substantially saturated with carbon dioxide; and treating the composition containing the biological or other sensitive substance with said carbon dioxide at a temperature and pressure substantially less than critical pressure and temperature for a prescribed treatment time to inactivate at least 80% of a target virus or viruses contained within the composition containing the biological or other sensitive substance; wherein the composition is maintained at temperatures of less than or equal to 30° C. during the carbon dioxide treatment.