Patent ID: 6825234
Filing Date: 2004-11-30
Classification: A61K,A61P,Y10S

Abstract:
A method for ameliorating female sexual arousal disorder, comprising the step of administering a composition to the genitalia of a human female in need of treatment, the composition comprising:an amount of a vasoactive prostaglandin effective to produce an increase in sexual arousal; a shear-thinning polysaccharide gum; a lipophilic component chosen from the group consisting of an aliphatic C1 to C8 alcohol, an aliphatic C8 to C30 ester, and mixtures thereof; a penetration enhancer chosen from the group consisting of alkyl-2-(N-substituted amino) alkanoates, (N-substituted amino) alkanol alkanoates, pharmaceutically acceptable salts thereof and mixtures thereof; water; and an acidic buffer system that provides a buffered pH of about 3.0 to about 7.4, wherein treatment increases subjective sexual arousal thereby alleviating symptoms of female sexual arousal disorder, wherein female sexual arousal disorder is the persistent or recurrent inability to attain, or to maintain, sufficient sexual excitement, which causes personal distress.