Patent ID: 6214318
Filing Date: 2001-04-10
Classification: A61K,A61P,Y10S

Abstract:
A therapeutic aerosol composition for topical use consisting of:(a) from about 10 to about 60 percent by weight of the following ingredients:oils selected from the group consisting of mineral oils, vegetable oils, silicone oils and synthetic oils;thickening agents for the oils in an amount sufficient to thicken the oils to a non-flowable state below about 35.degree. C., said thickening agents being selected from the group consisting of mineral waxes, animal and vegetable waxes, synthetic waxes, polymers and metallic soaps; andoptionally ingredients selected from the group consisting of an aqueous solution, adjuvants, topical therapeutic agents and emulsifiers, and(b) from about 40 to about 90 percent by weight of liquefied propellant, where at least about 80 percent by weight of the liquefied propellant is a non-polar propellant or mixture of non-polar propellants selected from the group consisting of hydrocarbon and fluorocarbon propellants, and the sum of (a) and (b) equals 100 percent by weight of the composition, the composition when expelled from an aerosol device depositing as an ointment having a solid or semi-solid consistency containing a substantial proportion of said propellant, whose evaporation is restrained by the solid or semi-solid nature of the deposit, thereby upon topical application producing a sustained cooling effect at a temperature between about -5.degree. C. and +5.degree. C.