Patent ID: 6080869
Filing Date: 2000-06-27
Classification: A61P,C07C,C07D

Abstract:
A process for preparing a compound of formula I, including optical isomers thereof, ##STR10## wherein X represents --SO.sub.2 NH-- or --NHSO.sub.2 --,p, q and r independently represent 2 or 3,Y represents thienyl optionally substituted by C.sub.1 -C.sub.6 alkyl or halogen, or phenylthio- or phenyl optionally substituted by C.sub.1 -C.sub.6 alkyl or halogen, andeach R independently represents H or C.sub.1 -C.sub.6 alkyl,and pharmaceutically acceptable salts thereof, the process comprising selectively reducing a compound of formula IV ##STR11## in which p, q, r, R, X and Y are as defined in formula (I) above.