Patent ID: 9000033
Filing Date: 2015-04-07
Classification: A61K,A61P,A61Q

Abstract:
1. A method for regulating skin condition comprising topically applying to skin a composition comprising Maclura pomifera (Osage orange) fruit extract encapsulated in a delivery vehicle, wherein said delivery vehicle is selected from the group consisting of a liposome, a maltodextrin, a polymeric matrix, a niasome and a nanoparticle, wherein said fruit extract is present in an amount of from about 0.0000001% to about 10% based on the total weight of the composition, wherein said application improves the appearance and condition of the skin by upregulating collagen 1A1 and elastin gene expression in normal human dermal fibroblasts, wherein said fruit extract comprises prenylated isoflavonoids.