Patent ID: 6783939
Filing Date: 2004-08-31
Classification: A61K,C07K,C12N

Abstract:
A composition comprising two or more isolated nucleic acids selected from the group consisting of an isolated nucleic acid encoding an env gene product or a fragment containing an epitope thereof of a human immunodeficiency virus, an isolated nucleic acid encoding a g&agr;g gene product or a fragment containing an epitope thereof of a human immunodeficiency virus, wherein the g&agr;g gene product or said fragment thereof is modified to inhibit formation of virus-like particles containing the g&agr;g gene product or said fragment thereof and their release from a cell, and an isolated nucleic acid encoding a pol gene product or a fragment containing an epitope thereof of a human immunodeficiency virus, wherein the pol gene product or said fragment thereof is modified to inhibit reverse transcriptase activity.