Patent ID: 6586179
Filing Date: 2003-07-01
Classification: A61P,C07K

Abstract:
An isolated nucleic acid encoding a polypeptide comprising an alpha subunit of a potassium channel, wherein the subunit:(i) forms, with at least one additional Eag family alpha subunit, a potassium channel having the characteristic of voltage sensitivity; and wherein said nucleic acid specifically hybridizes under stringent conditions to SEQ ID NO:1, wherein the hybridization reaction is incubated at 42Â° C. in a solution comprising 50% formamide, 5Ã—SSC, and 1% SDS or at 65Â° C. in a solution comprising 5Ã—SSC and 1% SDS, with a wash in 0.2Ã—SSC and 0.1% SDS at 65Â° C.