Patent ID: 8569356
Filing Date: 2013-10-29
Classification: A61K,G16B,G16C

Abstract:
1. A method of treating a subject suffering from breast cancer or prostate cancer, the method comprising administering to subject in need thereof a therapeutically effective amount of a compound capable of stabilizing the interaction of a cyclin-dependent kinase and a cdk inhibitor, or a compound capable of stabilizing an inactive conformation of a cyclin-dependent kinase and/or a complex of a cyclin-dependent kinase and a cyclin, such that the subject is treated wherein the compound is selected from the group consisting of 1-(5-methyl-thiophen-2-yl)-3-phenyl-propenone, 4-t-butyl-2-nitro-aniline, 3-amino-1-sulfanylidene-5,6,7,8-tetrahydroisothiochromene-4-carbonitrile, and 4-p-tolylamino-[1,2]naphthoquinone”.