Patent ID: 6667325
Filing Date: 2003-12-23
Classification: A61K,A61P,C07D,Y02A

Abstract:
A substituted pyrazole compound represented by the following formula, or a salt thereof wherein:R1 represents a group of any one of the following formulae i) to vii): i) â€”CH(OH)â€”CH(R4)â€”(A)nâ€”Y ii) â€”CH&boxH;C(R4)â€”(A)nâ€”Y iii) â€”CH2â€”CH(R4)â€”(A)nâ€”Y iv) â€”COâ€”B1â€”Aâ€”Y v) â€”Aâ€”B2â€”CH(R4)â€”Y vi) â€”Aâ€”CH(R4)â€”B2â€”Y vii) â€”CH(OH)â€”CH&boxH;C(R4)â€”Y in which A is â€”CH2â€” or â€”CH(CH3)â€”, Y is an aryl group which may optionally be substituted by halogen, lower alkyl, lower alkoxy, amino or nitro, or a cycloalkyl group, R4 is a hydrogen atom or a lower alkyl group, B1 is â€”CH(R4)â€”, B2 is â€”CH(OH)â€”, â€”COâ€” or â€”Oâ€”, and n is 1; R2 represents a hydrogen atom, a lower alkyl group which may optionally be substituted by hydroxyl, amino, or mono- or di-(lower alkyl)amino or an aralkyl group; R3 represents a phenyl group which may optionally be substituted by halogen, trifluoromethyl or lower alkylenedioxy, or a pyridyl group; and Q represents a pyridyl group.