Patent ID: 7848557
Filing Date: 2010-12-07
Classification: A61B,G01T

Abstract:
1. A method of recovering individual tracer signals from multi-tracer PET data comprising: introducing a plurality of tracers into a subject, wherein the plurality of tracers comprise a first tracer and at least a second tracer; obtaining multi-tracer PET data of the subject by performing a PET scan of the subject substantially concurrently or subsequent to introducing the first tracer and continuing at least a portion of the time after the introduction of the at least second tracer into the subject; providing a multi-tracer kinetic model, wherein said multi-tracer kinetic model estimates parameters or a time-dependent activity timecourse for each of said first and at least second tracer; applying said multi-tracer PET data to said multi-tracer kinetic model and estimating individual tracer signals for each of said first tracer and said at least second tracer at one or more timepoints based upon a fit of the multi-tracer PET data to the multi-tracer kinetic model; and applying said multi-tracer kinetic model to individual voxels or groups of voxels to recover static images for each of said first tracer and said at least second tracer, wherein said static images comprise rest or stress cardiac images.