Patent ID: 7173113
Filing Date: 2007-02-06
Classification: A61K,A61P

Abstract:
1. A composition of matter comprising (a) at least one subunit of a hormone or growth factor selected from the group consisting of VEGF, GH, TGFα, TGFβ1, EGF, FGF, SCF, IGF-I, IGF-II, GDF-9, KGF, BMP-15, GM-CSF, LIF, follistatin, activin-β, a neurotropin, angiopoiten I or II, MCP-1 and MIP-2 and (b) a serum half-life-increasing moiety, wherein the hormone or growth factor subunit and serum half-life-increasing moiety are covalently bound, and wherein the serum half-life-increasing moiety is a polypeptide comprising the amino acid sequence ser-gly-ser-asn-ala-thr-gly-ser-gly-ser-asn-ala-thr-ser-gly-ser (SEQ ID NO:9).