Patent ID: 8067379
Filing Date: 2011-11-29
Classification: A61K,A61P,C07D,C07K

Abstract:
1. A compound, or stereoisomer, rotamer, tautomer, or racemate of said compound, or a pharmaceutically acceptable salt of said compound or said stereoisomer, rotamer, tautomer, or racemate of said compound, or an ester of said compound or tautomer of said ester, said compound having the general structure shown in Formula I: wherein: R the moiety: R and Y is selected from the following moieties: wherein G is NH or O; and R 15 , R 16 , R 17 and R 18 can be the same or different, each being independently selected from the group consisting of H, alkyl, heteroalkyl, alkenyl, heteroalkenyl, alkynyl, heteroalkynyl, cycloalkyl, heterocyclyl, aryl, and heteroaryl, or alternately, (i) R 15 and R 16 are connected to each other to form a four to eight-membered cyclic structure, and (ii) likewise, independently R 17 and R 18 are connected to each other to form a three to eight-membered cycloalkyl or heterocyclyl; wherein each of said alkyl, aryl, heteroaryl, cycloalkyl or heterocyclyl can be unsubstituted or optionally independently substituted with one or more moieties selected from the group consisting of: hydroxy, alkoxy, aryloxy, thio, alkylthio, arylthio, amino, amido, alkylamino, arylamino, alkylsulfonyl, arylsulfonyl, sulfonamido, alkylsulfonamido, arylsulfonamido, alkyl, aryl, heteroaryl, keto, carboxy, carbalkoxy, carboxamido, alkoxycarbonylamino, alkoxycarbonyloxy, alkylureido, arylureido, halo, cyano, and nitro.