Patent ID: 6025467
Filing Date: 2000-02-15
Classification: A61K,C07K

Abstract:
A peptide having the following amino acid sequence or a salt thereof:Ser-Val-Ser-Glu-lle-Gln-Leu-Met-His-R.sub.1 -R.sub.2 -R.sub.3 -R.sub.4 -R.sub.5 -R.sub.6 -R.sub.7 -Met-R.sub.8 -Arg-R.sub.9 -Glu-Trp-Leu-Arg-R.sub.10 -R.sub.11 -Leu-Gln-R.sub.12 -Val-His-Asn-R.sub.13 (SEQ ID NO:2), wherein R.sub.1 represents Asp or Glu; R.sub.2 represents Phe, Lys, Leu or Ala (2-Naph); R.sub.3 represents Gly, D-Ala; R.sub.4 represents Orn or Lys; R.sub.5 represents His; R.sub.6 represents Leu; R.sub.7 represents Asn-Ser; Lys-Lys, Lys-Ser or Ser-Ser; R.sub.8 represents Glu; R.sub.9 represents Val; R.sub.10 represents Lys; R.sub.11 represents Lys or Gln; R.sub.12 represents Asp or 2-aminoisobutyric acid and R.sub.13 represents Phe.