Patent ID: 7300767
Filing Date: 2007-11-27
Classification: C12N,C12Q,G01N

Abstract:
1. A method for identifying herbicidally active inhibitors of carbamoyltransferase comprising: functionally expressing carbamoyltransferase in an expression system; measuring carbamoyltransferase activity from the expression system in the presence and absence of a test compound wherein, the carbamoyltransferase is encoded by a gene consisting essentially of SEQ ID NO: 1 or a derivative thereof comprising the coding region of a plant aspartate carbamoyltransferase and having at least 80% homology with SEQ ID NO:1 determining herbicidal activity of the test compound from the carbamoyltransferase activity by correlation of enzymatic activity of carbamoyltransferase with plant growth retardation; and identifying the test compound that is an herbicidally active inhibitor of carbamoyltransferase.