Patent ID: 9179997
Filing Date: 2015-11-10
Classification: A61B,A61F,A61L

Abstract:
1. A method of creating a thermochromic artificial blood vessel, the method comprising: physically cross-linking a polyvinyl alcohol solution at a temperature below 0° C. in an arterial mold so as to form an artificial blood vessel, the polyvinyl alcohol solution including polyvinyl alcohol and water; chemically cross-linking the physically cross-linked blood vessel with a chemical cross-linking solution, the chemical cross-linking solution including a chemical cross-linking reagent and water; and applying a coagulation solution to the chemically cross-linked blood vessel to both inhibit the chemical cross-linking and promote physical cross-linking of the artificial blood vessel, thereby imparting to the artificial blood vessel the ability to change color and/or transparency at locations thereof where temperature increases, the coagulation solution including water, a base, and a cross-linking promoter.