Patent ID: 6294349
Filing Date: 2001-09-25
Classification: G01N

Abstract:
A method of using a salivary soluble biomarker to diagnose carcinoma of the breast in a human test subject, said method comprising:providing a salivary secretion specimen from a human subject to provide an individual salivary protein biomarker diagnostic for carcinoma of the breast, said biomarker soluble in said salivary secretion and selected from the group consisting of cancer antigen 15-3, tumor suppressor oncogene protein 53, oncogene c-erbB-2, and combinations thereof;using the salivary secretion concentration of said individual biomarker to compare with a protein biomarker reference panel, said reference panel including mean concentration values for protein biomarker constituents of said panel; andidentifying the diagnosis for said subject indicated by said comparison.