Patent ID: 6737236
Filing Date: 2004-05-18
Classification: B01J,C07B,C07C,C07H,C07K,C12N,C40B

Abstract:
A method for bioconjugating macromolecules comprising the step of reacting a macromolecule derivatized with a moiety capable of undergoing a cycloaddition reaction, wherein said macromolecule is selected from the group consisting of nucleic acids, oligonucleotides, proteins, peptides, carbohydrates, polysaccharides, glycoproteins, lipids, hormones, drugs and prodrugs with a molecular entity derivatized with a moiety capable of reacting with said derivatized macromolecule via a cycloaddition reaction, wherein said derivatized macromolecule and said derivatized molecular entity are unassociated.