Patent ID: 7205318
Filing Date: 2007-04-17
Classification: A61P,C07D

Abstract:
1. A compound selected from: or a stereoisomer or pharmaceutically acceptable salt thereof, wherein: one of P G is a group of formula IIa or IIb: ring D, including the two atoms of Ring E to which it is attached, is a 5–6 membered ring consisting of carbon atoms; ring D is substituted with 0–2R and there are 0–3ring double bonds; E is selected from phenyl and pyridyl, and is substituted with 1–3 R; alternatively, ring D is absent and ring E is selected from phenyl, pyrrolyl, and thienyl, and ring E is substituted with 1–3 R; R is selected from H, C A is selected from: C B is  provided that Z and B are attached to different atoms on A and that the A-X-N moiety forms other than a N-N-N group; Q ring Q is a 6 membered monocyclic ring consisting of, in addition to the N-Q X is absent; G Z is selected from (CR R R R R R R R R R R R R R R R R R R R R R R R R R n, at each occurrence, is selected from 0, 1, 2, and 3; p, at each occurrence, is selected from 0, 1, and 2; r, at each occurrence, is selected from 0, 1, 2, 3, 4, 5, and 6; r1, at each occurrence, is selected from 1, 2, 3, 4, 5, and 6; and t, at each occurrence, is selected from 0, 1, 2, and 3.