Patent ID: 6794139
Filing Date: 2004-09-21
Classification: A61K,C07K

Abstract:
A process for detecting the presence or absence, in a mammary tumor, of the mRNA encoded by the nucleic acid sequence shown in ID NO: 1, comprising:(a) obtaining from a patient a cell containing mRNA from the mammary tumor; (b) contacting the mRNA with an oligonucleotide consisting of a nucleic acid sequence of SEQ ID NO: 1 or a nucleic acid sequence, though not identical to SEQ ID NO: 1, due to the degeneracy of the genetic code encodes a polypeptide having the amino acid sequence of the polypeptide encoded by SEQ ID NO:1; and (c) detecting the presence or absence of hybridization of the mRNA from the cell to the oligonucleotide of step(b) wherein the presence of hybridization indicates the presence of a PAP mRNA in the cell and that the cell has the tendency to form metastases.