Patent ID: 6071530
Filing Date: 2000-06-06
Classification: A61K,A61L,B29C,B29K

Abstract:
A method of treating a bone tissue defect in an animal, the method comprising:dispensing a polymer solution onto a support substrate surrounded by an aqueous medium or body fluid;wherein the polymer solution comprises a pharmaceutically acceptable biodegradable, thermoplastic polymer that is insoluble in the aqueous medium or body fluid; in combination with a biocompatible organic solvent that solubilizes the polymer and is miscible to dispersible in the aqueous medium or body fluid; and a bone growth promoting substance, wherein the polymer solution is in a liquid form, wherein the support substrate is a tissue in the animal and the organic solvent diffuses into the aqueous medium or body fluid and the thermoplastic polymer coagulates to form a solid microporous implant in which the bone growth promoting substance is incorporated when the polymer solution is dispensed on the support substrate.