Patent ID: 6265610
Filing Date: 2001-07-24
Classification: A61K,C07C,C07D

Abstract:
A compound of the formula: ##STR21##wherein:R1 is selected from the group consisting of alkyl and alkyl substituted with hydroxy or alkoxy;R2, R3 and R4 are each independently selected from the group consisting of hydrogen and alkyl;R5 and R6 are each independently selected from the group consisting of hydrogen, alkyl and hydroxyalky,n is from 1 to 3;Z is --A--NHCH3 or Z is hydroxy-C2-5-alkylamino;A is: ##STR22##whereinR7 is H or alkyl;R8 is H, alkyl, or alkyl substituted by hydroxy or alkoxy;or together R7 and R8 form a propylene or hydroxypropylene ring;m is 0 or 1;R9 and R10 are each independently H or alkyl; or R9 and R10 together form C4-C8 alkylene which is unsubstituted or substituted from one to three times with alkyl or hydroxy;R11 is amino or guanidino;o is from two to six;or a physiologically acceptable salt thereof.