Patent ID: 8022065
Filing Date: 2011-09-20
Classification: A61P,C07D

Abstract:
1. A compound selected from: 3-(6-((morpholin-4-yl)carbonyl)-6,7-dihydro-6H-[1,4]diazepino[6,7,1-hi]indol-1-yl)-4-(imidazo[1,2-a]-pyridin-3-yl)-2,5-dioxopyrrole; 3-(6-(N,N-[dimethyl]aminocarbonyl)-6,7-dihydro-6H-[1,4]diazepino[6,7,1-hi]indol-1-yl)-4-(imidazo[1,2-a]pyridin-3-yl)-2,5-dioxopyrrole; 3-(6-(isopropoxycarbonyl)-6,7-dihydro-6H-[1,4]di-azepino[6,7,1-hi]indol-1-yl)-4-(imidazo[1,2-a]pyridin-3-yl)-2,5-dioxopyrrole; 3-((6-(piperidin-1-yl)carbonyl)-6,7-dihydro-6H-[1,4]diazepino[6,7,1-hi]indol-1-yl)-4-(imidazo[1,2-a]pyridin-3-yl)-2,5-dioxopyrrole; 3-((6-(piperidin-1-yl)carbonyl)-6,7-dihydro-6H-[1,4]diazepino[6,7,1-hi]indol-1-yl)-4-(imidazo[1,2-b]pyridazin-3-yl)-2,5-dioxopyrrole; 3-(6-((morpholin-4-yl)carbonyl)-6,7-dihydro-6H-[1,4]-diazepino[6,7,1-hi]indol-1-yl)-4-(4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridin-3-yl)-2,5-dioxopyrrole; 3-(6-((pyridin-3-yl)carbonyl)-6,7-dihydro-6H-[1,4]diazepino[6,7,1-hi]indol-1-yl)-4-(imidazo[1,2-a]pyridin-3-yl)-2,5-dioxopyrrole; 3-(6-(pyrimidin-2-yl)-6,7-dihydro-6H-[1,4]diazepino[6,7,1-hi]indol-1-yl)-4-(imidazo[1,2-a]pyridin-3-yl)pyrrole-2,5-dione; or a pharmaceutically acceptable salt thereof.