Patent ID: 9181182
Filing Date: 2015-11-10
Classification: A61P,C07C,C07D

Abstract:
1. A compound having the structure of any one of formulae (8) to (13), or a stereoisomer, isotopic form, or pharmaceutically acceptable salt thereof: wherein X is N; X R R A is hydrogen, deuterium or optionally substituted (C R wherein Ar is an optionally substituted 5-12 atom aromatic or heteroaromatic ring system; B, C, D, E and F are independently selected from C(R) G and H are independently hydrogen, deuterium or optionally substituted (C Q and Q m is 0-5; X′ is C(R) X′, Y and Z are independently C(R) R is hydrogen, deuterium, alkoxy, cyano, amino, hydroxyl, halogen, nitro, carbonyl, carboxy, amido, trifluoromethyl, trihaloalkyl, trifluoroalkoxy or a C R′ and R′ n is 0-2; and n″ is 0-1.