Patent ID: 7732190
Filing Date: 2010-06-08
Classification: A61K,A61L,A61P

Abstract:
1. A kit for a post-myocardial infarct bioscaffolding gel, the kit separately comprising the following components: (a) a first mixture comprising a first functionalized polymer in a first buffer, the first buffer having a physiological osmolality; (b) a second buffer having a concentration of 140 mM to 150 mM and a pH between 7.5 and 9; (c) a second functionalized polymer different from the first functionalized polymer, the second functionalized polymer capable of being combined with the first mixture or the second buffer; and (d) a proteinaceous or peptide substance having at least one cell-adhesion site, the substance capable of being combined with the first mixture, wherein the first functionalized polymer is a functionalized polyethylene glycol selected from the group consisting of an activated ester-terminated polyethylene glycol or a vinyl-terminated polyethylene glycol; wherein the second functionalized polymer is selected from the group consisting of a thiol-terminated polyethylene glycol or an amino-terminated polyethylene glycol; and wherein the components, when combined, form a gel having a pH of 7.2.