Patent ID: 6589553
Filing Date: 2003-07-08
Classification: A61K

Abstract:
A controlled release bupropion formulation comprising:(a) a first component comprising immediate release bupropion and its salts, isomers or a pharmaceutically acceptable aminoketone antidepressant; (b) a second component comprising pellets comprising: (i) a core comprising (1) an inert carrier, (2) bupropion and its salts, isomers, or a pharmaceutically acceptable aminoketone antidepressant agent; and (3) a binder; and (ii) a coating comprising a pH dependent coating agent; and (c) a third component comprising pellets comprising: (i) a core comprising (1) an inert carrier, (2) bupropion and its salts, isomers, or a pharmaceutically acceptable aminoketone antidepressant agent; and (3) a binder; and (ii) a coating comprising (I) a water insoluble methyl acrylic acid copolymer and (II) a water soluble polymer.