Patent ID: 6197552
Filing Date: 2001-03-06
Classification: C12P

Abstract:
A process for preparing 2'-deoxyguanosine, comprising:contacting 2'-deoxyribose-1-phosphoric acid or a salt thereof and 2,6-diaminopurine with a microorganism which produces, 2,6-diaminopurine-2'-deoxyriboside from 2'-deoxyribose-1-phosphoric acid or a salt thereof and 2,6-diaminopurine, or with cells or cell lysate of said microorganism; andcontacting the 2,6-diaminopurine-2'-deoxyriboside with an adenosine deaminase in an aqueous medium to produce the 2'-deoxyguanosine;wherein said microorganism belongs to a genus selected from the group consisting of Achromobacter, Agrobacterium, Acinetobacter, Alcaligenes, Arthrobacter, Aeromonas, Escherichia, Enterobacter, Erwinia, Xanthomonas, Klebsiella, Kurthia, Kluyvera, Corynebacterium, Sartina, Salmonella, Citrobacter, Pseudomonas, Streptomyces, Sporosarcina, Staphyrococcus, Serratia, Cellulomonas, Nocardia, Hafnia, Vibrio, Flavobacterium, Planococcus, Brevibacterium, Protaminobacter, Proteus, Haemophilus, Micrococcus, Mycoplana, Microbacterium, Rhizobium and Rhodococcus.