Patent ID: 8080395
Filing Date: 2011-12-20
Classification: A23K,C12N,C12P

Abstract:
1. A process for producing an L-amino acid, comprising: a) fermenting an isolated coryneform bacterium in a suitable medium, wherein the bacterium comprises at least one copy of a gene which encodes for a polypeptide having 2-methylcitrate dehydratase activity, wherein the polypeptide comprises the amino acid sequence of SEQ ID NO: 2 except that one of the proteinogenic amino acids other than L-proline is present at position 272 or at a corresponding or comparable position; or wherein said polypeptide comprises an amino acid sequence at least 90% identical to SEQ ID NO: 6 or SEQ ID NO: 8 except that one of the proteinogenic amino acids other than L-proline is present at position 272 or at a corresponding or comparable position, and b) accumulating the L-amino acid in the fermentation medium or inside the bacterial cells.