Patent ID: 6326378
Filing Date: 2001-12-04
Classification: A61K,A61P

Abstract:
A method of treating leukemia comprising:administering to a recipient diagnosed with leukemia a therapeutically effective amount of a compound of formula I ##STR4##in whichX.sup.1 and X.sup.2, individually are hydrogen, a C.sub.1 - to C.sub.6 -alkyl radical or a halogen atom or, if they are in adjacent positions, form a fused phenyl ring together with the carbon atoms carrying them, andR is a carbocyclic or heterocyclic saturated or unsaturated radical, optionally mono- or polysubstituted by halogen, cyano, nitro, C.sub.1 - to C.sub.6 -alkyl, C.sub.1 - to C.sub.6 -haloalkyl, hydroxyl, C.sub.1 - to C.sub.6 -alkoxy, methylenedioxy, C.sub.1 - to C.sub.6 -alkylthio, C.sub.1 - to C.sub.6 -haloalkylthio, amino, C.sub.1 - to C.sub.6 -alkylamino, C.sub.2 - to C.sub.12 -dialkylamino, pyrrolyl, carboxyl, carbamoyl, benzyl, C.sub.1 - to C.sub.6 -hydroxyalkyl, C.sub.2 - to C.sub.7 -carboxyalkyl, C.sub.2 - to C.sub.7 -alkoxycarbonyl-C.sub.1 - to C.sub.6 -alkyl, carbamoyl-C.sub.1 - to C.sub.6 -alkyl, N-hydroxy-N--C.sub.1 - to C.sub.6 -alkylcarbamoyl-C.sub.1 - to C.sub.6 -alkyl or C.sub.2 - to C.sub.6 -alkenyl,or a physiologically tolerable salt of a compound of formula I.