Patent ID: 6358528
Filing Date: 2002-03-19
Classification: A61K

Abstract:
A tablet formulation for oral administration comprising amoxycillin and clavulanate in a ratio of 30:1 to 1:1 in which 25 to 75% of the total weight of amoxycillin and 25 to 75% of the total weight of clavulanate is in a central core which is surrounded by a release-retarding coating layer which is an enteric polymer coating, and a casing layer surrounding the core containing from 75 to 25% of amoxycillin and from 75 to 25% of clavulanate, such that there is an initial quick release of amoxycillin and clavulanate from the casing layer and a sustained release of amoxycillin and clavulanate from the core.