Patent ID: 6328962
Filing Date: 2001-12-11
Classification: A61K,A61P,C07K,C12N

Abstract:
A method of generating an immune response in a host, comprising:administering thereto an immuno-effective amount of an immunogenic composition comprising a recombinant conjugate antibody molecule, consisting of a bivalent monoclonal antibody moiety having the entire heavy and light chains and specific for a surface structure of antigen presenting cells, said monoclonal antibody moiety being genetically modified to contain at least one antigen moiety, each said antigen moiety being located exclusively at a preselected site on said monoclonal antibody moiety, whereby said conjugate antibody molecule is capable of delivering said antigen moiety to the antigen presenting cells of a host and capable of eliciting an immune response to said antigen moiety in the host.