Patent ID: 8039511
Filing Date: 2011-10-18
Classification: A61K,A61P

Abstract:
1. A method for the treatment of benign prostatic hyperplasia in a subject, comprising: administrating, to the subject, a composition comprising an effective amount of at least one compound of isothiocyanates, their derivatives, or metabolites, wherein the isothiocyanates are selected from the group consisting of benzyl isothiocyanate (BITC), phenethyl isothiocyanate (PEITC), and allyl isothiocyanate (AITC),which have the following formulas (1), (2), and (3), respectively, or the combination thereof: and wherein the derivatives, or metabolites of isothiocyanates are selected from the group consisting of N-acetylcysteine conjugate of benzyl isothiocyanate (BITC-NAC), N-acetylcysteine conjugate of phenethyl isothiocyanate (PEITC-NAC), and N-acetylcysteine conjugate of allyl isothiocyanate (AITC-NAC), which have the following formulas (5), (6), and (7), respectively, or the combination thereof: