Patent ID: 7442516
Filing Date: 2008-10-28
Classification: C07K,G01N,Y10S,Y10T

Abstract:
1. An isolated antibody specific to a central nervous system (CNS) tau protein, wherein the antibody specifically recognizes a CNS tau protein but not a peripheral tau protein, wherein the antibody is obtained by immunizing an animal with a polypeptide comprising an amino acid sequence specific to the CNS tau protein consisting of amino acid residues 124-125 of SEQ ID NO: 1 and wherein the antibody specifically recognizes the amino acid sequence specific to CNS tau protein as contained in a polypeptide consisting of amino acid residues selected from the group consisting of 121-128 of SEQ ID NO: 1, 118-131 of SEQ ID NO: 1, and 121-129 of SEQ ID NO: 1.