Patent ID: 7879886
Filing Date: 2011-02-01
Classification: A61K,A61P,C07D,Y02A

Abstract:
1. A pharmaceutical composition comprising an amount of a compound represented by formula (I) sufficient to reduce the population of Plasmodium in a human infested with Plasmodium protozoans and suffering from malaria, in combination with a pharmaceutically acceptable excipient, wherein formula (I) is where: R is OH, OR R R R R R R R R R R R A is N, CH or COH; B is S, O, N, CH a is 2 or 3; b is 0 or 1; m is an integer from 1 to 8; n is 0 or 1; p is 0, 1 or 2; r is 2 or 3; wherein each of the substituents shown is defined above, or a compound of formula (I) where the ring containing the B and N moieties is fully reduced and contains no double bonds, or a pharmaceutically acceptable salt of the compound represented by formula (I) or a stereoisomer of the compound or mixture of stereoisomers.