Patent ID: 6124490
Filing Date: 2000-09-26
Classification: A61K,A61Q,C08G,C08L

Abstract:
A method of preparing an ionically cross-linked composition of a thickened gel-like consistency comprising reacting(A) a diamino containing polysiloxane of the general formula: ##STR17## wherein: R, which can be the same or different, is selected from R.sub.2 or --OR.sub.9, wherein R.sub.9 is hydrogen or alkyl;R.sub.1 can be the same or different and is selected from R, R.sub.2 and a diamino containing radical of the formula --F.sub.1 --NR.sub.5 --F--NH.sub.2 ; with the proviso that at least one R.sub.1 group is a diamino containing radical wherein; F.sub.1 is linear or branched alkylene of 1-12 carbon atoms; F is linear or branched alkylene of 1-10 carbon atoms; and R.sub.5 is hydrogen or lower alkyl;R.sub.2 can be the same or different and is selected from R or substituted or unsubstituted alkyl, aryl and olefinic (vinyl);R.sub.3 and R.sub.4, which can be the same or different, are selected from substituted or unsubstituted alkyl, aryl, capped or uncapped polyoxyalkylene, alkarylene, aralkylene or alkenyl;a is an integer from 0 to 10,000; andb is an integer from 10 to 1000; with the proviso that when a pendant R.sub.1 group is a diamino containing radical, a can be 0 or a and b are present in the ratio of a:b of at least 1:1 to about 200:1;with (B), an acid containing reactant selected from itaconic acid and/or the trialkylsilyl ester derivatives thereof; substituted or unsubstituted cyclic acid anhydride; substituted or unsubstituted conjugated olefinic acid and mixtures of the same at an elevated temperature in the presence of (C) a low molecular weight silicone oil or other solvent for a time sufficient to form an ionically cross-linked zwitterionic siloxane polymer of a gel-like consistency containing both carboxylic acid and secondary and/or tertiary amino radicals.