Patent ID: 6653486
Filing Date: 2003-11-25
Classification: C07D,C08F,Y10S

Abstract:
A compound of the formula: whereinR1-R8 are independently selected from the group consisting of hydrogen; alkyl; aryl; substituted alkyl; substituted aryl; 6-oxabicyclo[3.1.0]hex-2-yl; 6-oxabicyclo[3.1.0]hex-3-yl; (6-oxabicyclo[3.1.0]hex-2-yl)methyl; (6-oxabicyclo[3.1.0]hex-3-yl)methyl; (6-oxabicyclo[3.1.0]hex-2-yl)methoxy; (6-oxabicyclo[3.1.0]hex-3-yl)methoxy; 7-oxabicyclo[4.1.0]hept-2-yl; 7-oxabicyclo[4.1.0]hept-3-yl; (7-oxabicyclo[4.1.0]hept-2-yl)methyl; (7-oxabicyclo[4.1.0]hept-3-yl)methyl; (7-oxabicyclo[4.1.0]hept-2-yl)methoxy; (7-oxabicyclo[4.1.0]hept-3-yl)methoxy; and â€”(CH2)nâ€”Oâ€”(O&boxH;C)â€”R9, where n=1 through 9 and R9=H, alkyl, aryl, substituted alkyl and substituted aryl, or R1â€¢R2, R2â€¢R3, R5â€¢R6, and R6â€¢R7 are independently selected from the group consisting of â€”CH2(CH2)nCH2â€” where n=3, 4, 5, and 6 and â€”CH2-epoxy-(CH2)nâ€”CH2â€” where n=0, 1, and 2, and â€”Oâ€” so as to form an alicyclic ring or an oxirane ring between R1 and R2, R2 and R3, R5 and R6, or R6 and R7; provided that the compound contains at least one epoxy or oxirane group and provided thatR1, R4, R5, and R8 are hydrogen when R2 is independently selected from the group consisting of 6-oxabicyclo[3.1.0]hex-2-yl, 6-oxabicyclo[3.1.0]hex-3-yl, (6-oxabicyclo[3.1.0]hex-2-yl)methyl, (6-oxabicyclo[3.1.0]hex-3-yl)methyl, (6-oxabicyclo[3.1.0]hex-2-yl)methoxy, (6-oxabicyclo[3.1.0]hex-3-yl)methoxy, 7-oxabicyclo[4.1.0]hept-2-yl, 7-oxabicyclo[4.1.0]hept-3-yl, (7-oxabicyclo[4.1.0]hept-2-yl)methyl, (7-oxabicyclo[4.1.0]hept-3-yl)methyl, (7-oxabicyclo[4.1.0]hept-2-yl)methoxy, (7-oxabicyclo[4.1.0]hept-3-yl)methoxy, and R3, R6, and R7 are independently selected from the group consisting of hydrogen, alkyl, aryl, substituted alkyl, and substituted aryl; R1, R4, R5, and R8 are hydrogen when R2 and R3 are independently selected from the group consisting of 6-oxabicyclo[3.1.0]hex-2-yl, 6-oxabicyclo[3.1.0]hex-3-yl, (6-oxabicyclo[3.1.0]hex-2-yl)methyl, (6-oxabicyclo[3.1.0]hex-3-yl)methyl, (6-oxabicyclo[3.1.0]hex-2-yl)methoxy, (6-oxabicyclo[3.1.0]hex-3-yl)methoxy, 7-oxabicyclo[4.1.0]hept-2-yl, 7-oxabicyclo[4.1.0]hept-3-yl, (7-oxabicyclo[4.1.0]hept-2-yl)methyl, (7-oxabicyclo[4.1.0]hept-3-yl)methyl, (7-oxabicyclo[4.1.0]hept-2-yl)methoxy, (7-oxabicyclo[4.1.0]hept-3-yl)methoxy, and R3 and R7 are independently selected from the group consisting of hydrogen, alkyl, aryl, substituted alkyl, and substituted aryl; R3, R4, R5, R6, R7, and R8 are independently selected from the group consisting of the group consisting of hydrogen, alkyl, aryl, substituted alkyl, and substituted aryl, when R1â€¢R2=â€”Oâ€” so as to form an oxirane ring between R1 and R2; R3, R4, R7, and R8 are independently selected from the group consisting of the group consisting of hydrogen, alkyl, aryl, substituted alkyl, and substituted aryl, when R1â€¢R2 and R5â€¢R6=â€”Oâ€” so as to form an oxirane ring between R1 and R2 and between R5 and R6; R1, R4, R5, and R8 are hydrogen when R2 and R3 are ethyl and R6 â€¢R7 are â€”CH2-epoxy-(CH2)nâ€”CH2â€” where n=1 and 2 so as to form an alicyclic ring between R6and R7; and R1, R4, R5, and R8 are hydrogen when R2â€¢R3 and R6â€¢R7 are â€”CH2-epoxy-(CH2)nâ€”CH2â€” where n=1 and 2 so as to form an alicyclic ring between R2 and R3 and R6 and R7.