Patent ID: 6071917
Filing Date: 2000-06-06
Classification: A61P,C07D

Abstract:
A compound derived from N-benzenesulfonyl-(L)-proline, wherein said compound is selected from the group consisting of:(i) a compound of formula I ##STR78## in which: X.sub.1 and X.sub.2 are each independently a halogen atom or a C.sub.1 -C.sub.3 -alkoxy group,R.sub.1 is a hydrogen atom, a C.sub.1 -C.sub.3 -trifluoroalkyl group or a C.sub.1 -C.sub.3 -alkyl group with a linear or branched hydrocarbon chain,R.sub.2 is a hydrogen atom or an OH group,A is a group ##STR79## B is a single bond, --CO--, --CO--CH.sub.2 --, --CO--CH.sub.2 --O--, CO--CH.dbd.CH-- or --SO.sub.2 --,m is 2 or 3,n is 0, 1, 2 or 3,R.sub.3 is a hydrogen atom or a methyl group, andW is CH or N,the amidine group C(.dbd.NR.sub.2)NH.sub.2 being in the 2-, 3- or 4-position on the aromatic ring; and(ii) its addition salts.