Patent ID: 7915002
Filing Date: 2011-03-29
Classification: A61P,G01N

Abstract:
1. A method for guiding non-surgical therapeutic treatment of a patient suffering from chronic cardiac insufficiency, said method comprising determining the concentration of at least two inactive peptides each of which is derived from the same propeptide precursor as a vasoactive peptides selected from the group consisting of adrenomedullin (ADM), endothelin-1 (ET-1) and vasopressin (AVP) in the blood of the patient before and after beginning therapy and comparing said before- and after-concentrations for each of said at least two inactive peptides wherein the at least two inactive peptides determined are selected from the group consisting of MR-proADM, CT-proET-1 and CT-proAVP, wherein no reduction of said concentrations indicates that the therapeutic measures are unsatisfactory and the therapeutic measures are changed, and wherein a reduction in said concentration indicates successful therapy.