Patent ID: 8415113
Filing Date: 2013-04-09
Classification: C07K,C12N

Abstract:
1. A diagnostic method for determining pancreatic function in a human patient, the method comprising the steps of: providing two or more different purified polyclonal antibodies each elicited against an immunogenic composition comprising a conjugate consisting of a non-elastase carrier protein and one or more synthetic peptides selected from the group consisting of wherein said different antibodies are each specific for human pancreatic elastase 1; obtaining a sample of a bodily fluid or stool from the patient; mixing the sample with the two or more different purified antibodies to form specific immune complexes among the antibodies and human pancreatic elastase 1 present in the sample; and detecting an amount of the immune complexes to determine an amount of human pancreatic elastase 1 in the sample, wherein the amount of human pancreatic elastase 1 in the sample is indicative of pancreatic function in the patient.