Patent ID: 6437124
Filing Date: 2002-08-20
Classification: A61P,C07D

Abstract:
A compound selected from the group consisting of:(E)-4-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) cinnamic acid triethylene glycol methyl ether ester; (E)-4-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) cinnamic acid polyethylene glycol (n=7.2) methyl ether ester; (E)-4-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) cinnamic acid tetraethylene glycol methyl ether ester; (E)-4-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) cinnamic acid pentaethylene glycol methyl ether ester; (E)-4-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) cinnamic acid hexaethylene glycol methyl ether ester; (E)-4-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) cinnamic acid heptaethylene glycol methyl ether ester; (E)-4-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) cinnamic acid octaethylene glycol methyl ether ester; (E)-4-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) cinnamic acid polyethylene glycol (n=11.7) methyl ether ester; (E)-4-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) cinnamic acid hexaethylene glycol ester; (E)-4-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) cinnamic acid polyethylene glycol (n=23.9) methyl ether ester; (E)-4-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) cinnamic acid polyethylene glycol (n=41.5) methyl ether ester; (E)-4-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) cinnamic acid polyethylene glycol (n=15) methyl ether ester; (E)-4-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) cinnamic acid polyethylene glycol (n=32.2) ester; (E)-4-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) cinnamic acid polyethylene glycol (n=18.9) ester; (E)-4-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) cinnamic acid polyethylene glycol (n=13) ester; (E)-3-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) benzoic acid nonaethylene glycol methyl ether ester; (E)-2-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-2,6-dioxo-9H-purin-8-yl) benzoic acid nonaethylene glycol methyl ether ester; (E)-4-(1,3-Bis(cyclohexylmethyl)-1,2,3,6-tetrahydro-6-oxo-2-thioxo-9H-purin-8-yl) cinnamic acid nonaethylene glycol methyl ether ester; and pharmaceutically acceptable solvates thereof.