Patent ID: 8703102
Filing Date: 2014-04-22
Classification: A61K,G01R

Abstract:
1. A process for manufacturing a hyperpolarized material, comprising: a) providing a first material to be polarized, the first material including a methyl rotor group; b) increasing the polarization of at least one hydrogen nuclei in the methyl group of the first material by exposing the first material to a polarizing environment inside of a cryostat by (i) decreasing the temperature of the first material, and (ii) subjecting the first material to an increased magnetic field, wherein the first material is exposed to the polarizing environment for a time sufficient to polarize at least one hydrogen nuclei contained in the first material to thermodynamic equilibrium; and c) transferring at least some of the increased polarization of the at least one hydrogen nuclei to at least one other nuclei in the first material by directing the first material out of the cryostat, through a region of decreased magnetic field on the order of the Earth's background magnetic field to a second location.