Patent ID: 7402577
Filing Date: 2008-07-22
Classification: A61K,A61P,C07J

Abstract:
1. A compound selected from the group consisting of: (17β)-3-oxo-N-(2-trifluoromethylphenyl)-androst-4-ene-17-carboxamide; (17β)-3-oxo-N-(3-trifluoromethylphenyl)-androst-4-ene-17-carboxamide; (17β)-3-oxo-N-(4-trifluoromethylphenyl)-androst-4-ene-17-carboxamide; (17β)-N-(2-methoxyphenyl)-3-oxoandrost-4-ene-17-carboxamide; (17β)-N-(3-methoxyphenyl)-3-oxoandrost-4-ene-17-carboxamide; (17β)-N-(4-methoxyphenyl)-3-oxoandrost-4-ene-17-carboxamide; (17β)-N-(2-chlorophenyl)-3-oxoandrost-4-ene-17-carboxamide; (17β)-N-(3-chlorophenyl)-3-oxoandrost-4-ene-17-carboxamide; (17β)-N-(4-chlorophenyl)-3-oxoandrost-4-ene-17-carboxamide; (17β)-N-(2-methylphenyl)-3-oxoandrost-4-ene-17-carboxamide; (17β)-N-(3-methylphenyl)-3-oxoandrost-4-ene-17-carboxamide; (17β)-N-(4-methylphenyl)-3-oxoandrost-4-ene-17-carboxamide; (17β)-N-(2-fluorophenyl)-3-oxoandrost-4-ene-17-carboxamide; (17β)-N-(3-fluorophenyl)-3-oxoandrost-4-ene-17-carboxamide; (17β)-N-(4-fluorophenyl)-3-oxoandrost-4-ene-17-carboxamide; (17β)-N-(2-bromophenyl)-3-oxoandrost-4-ene-17-carboxamide; (17β)-N-(2-iodophenyl)-3-oxoandrost-4-ene-17-carboxamide; (17β)-N-(3-methoxy-5-trifluoromethylphenyl)-3-oxoandrost-4-ene-17-carboxamide; (17β)-N-methyl-3-oxo-4-(2-trifluoromethylphenyl)-androst-4-ene-17-carboxamide; (17β)-4-methyl-3-oxo-N-(2-trifluoromethylphenyl)-androst-4-ene-17-carboxamide; (17β)-7-methyl-3-oxo-N-(2-trifluoromethylphenyl)-androst-4-ene-17-carboxamide; (17β)-6-methylene-3-oxo-N-(4-trifluoromethylphenyl)-androst-4-ene-17-carboxamide; (17β)-N-(4-fluorophenyl)-6-methylene-3-oxo-androst-4-ene-17-carboxamide; (17β)-6α-ethyl-3-oxo-N-(4-trifluoromethylphenyl)-androst-4-ene-17-carboxamide; (17β)-6β-ethyl-3-oxo-N-(4-trifluoromethylphenyl)-androst-4-ene-17-carboxamide; (17β)-6,6-ethyleno-3-oxo-N-(4-trifluoromethylphenyl)-androst-4-ene-17-carboxamide; (1aR,5aR,7aS,8S,10cR)-5a,7a-dimethyl-3-oxo-N-phenyl-1,1a, 3,4,5,5a,5b,6,7,7a,8,9,10,10a,10b,10c-hexadecahydro- cyclopenta[a]cyclopropa[1]phenanthrene-8-carboxamide; and (1aS,5aR,7aS,8S,10cS)-5a,7a-dimethyl-3-oxo-N-phenyl-1,1a, 3,4,5,5a,5b,6,7,7a,8,9,10,10a, 10b, 10c-hexadecahydro-cyclopenta[a]cyclopropa[1]phenanthrene-8-carboxamide; or a pharmaceutically acceptable salt thereof.