Patent ID: 6770652
Filing Date: 2004-08-03
Classification: A61P,C07D

Abstract:
A compound, and pharmaceutically acceptable salts, solvates and prodrugs thereof, having the formula (3): where X is NIIâ€” and R1 is present;X2 is from one to three atoms, and if R3 is not present, is independently selected from the group consisting of hydrogen, an alkyl group, an alkenyl group, a heteroalkyl group and a heteroalkenyl group, and if R3 is present, X2 is selected from the group consisting of an alkenyl group, a heteroalkylene group, an alkenylene group, and a heteroalkenylene group; and any carbons or nitrogens of said alkyl group, alkylene group, alkenyl group, alkenylene group, heteroalkylene group, hetroalkylene group, heteroalkenylene group or heteroalkenyl group can optionally be substituted with a straight or branched lower alkyl group or alicyclic group of from 1 to 6 carbons; R3 is optionally present; R1 is selected from the group consisting of an alicyclic group, a heterocyclic group, an aryl group, a heteroaryl group, an alkylaryl group, a alkylheteroaryl group, a substituted aryl group, a substituted heteroaryl group, a substituted alkylaryl group and a substituted alkylheteroaryl group; if present, R3 is selected from group consisting of hydrogen, an alicyclic group, a heterocyclic group, an aryl group, a heteroaryl group, an alkylaryl group, a alkylheteroaryl group, a substituted aryl group, a substituted heteroaryl group, a substituted alkylaryl group, a substituted alkylheteroaryl group, and a 4-(1,3-dicarboxyl propyl amino carbonyl) aryl group; and each substituent of any substituted group is the same or different and is selected from the group consisting of a straight or branched lower alkyl, alkenyl, alkynl or alicyclic group of from one to 6 carbons, an alkoxy group, an alkoxyaryloxy group, and a halogen.