Patent ID: 6114392
Filing Date: 2000-09-05
Classification: A61K,C07D

Abstract:
Compounds of general formula II: ##STR7## wherein: n is 1 or 2;R.sub.1, R.sub.2 and R.sub.3 are each independently hydrogen, hydroxy, substituted or unsubstituted C.sub.1-4 alkyl, substituted or unsubstituted C.sub.1-4 alkoxy halogeno, amino, phenyl or R.sub.4 NR.sub.5 ;R.sub.4 and R.sub.5 are each independently, (CH.sub.2).sub.a --[NH(CH.sub.2).sub.x ].sub.y --NHR.sub.6, (CH.sub.2).sub.a --[NH(CH.sub.2).sub.x ].sub.y --NH--NHR.sub.6, (CH.sub.2).sub.a --[NH(CH.sub.2).sub.x ].sub.y --(NR.sub.7 .dbd.)CNHR.sub.6, or (CH.sub.2).sub.a --[NH(CH.sub.2).sub.x ].sub.y --NH(NR.sub.7 .dbd.)CNHR.sub.6, wherein a is 0-5, y is 1-5 and x is 1-5;R.sub.6 and R.sub.7 are each independently hydrogen, hydroxy, substituted or unsubstituted C.sub.1-4 alkyl, substituted or unsubstituted C.sub.1-4 alkoxy, or halogeno;and pharmaceutically acceptable salts and optically active isomers thereof.