Patent ID: 8551511
Filing Date: 2013-10-08
Classification: A61L,C08G,C08L

Abstract:
1. A biocompatible polymer composition, comprising at least a first polymer phase and a second polymer phase; the first polymer phase having at least one first wet thermal transition temperature selected from a first wet glass transition temperature and a first wet melting point, the first wet thermal transition temperature being at least 38° C.; the first polymer phase comprising a number (n) of first recurring units of the formula (I): wherein: X q and r are each independently zero or one, where q+r=1 or 2; each A each R each R each R R  and optionally ring-halogenated  wherein q=0 when R each a is independently zero or an integer in the range of 1 to 8; each Z is independently an O or an S; and Q Q the second polymer phase having at least one second wet thermal transition temperature selected from a second wet glass transition temperature and a second wet melting point, the second wet thermal transition temperature being 36° C. or lower, the second polymer phase comprising a number (m) of second recurring units of the formula (IId): wherein D wherein the number (n) and the number (m) are selected to control the relative amounts of the first polymer phase and the second polymer phase so that (a) the polymer composition is phase-separated over at least the temperature range of about 25° C. to about 50° C., (b) the polymer composition has a water content of 4.5% or less as measured after soaking for 24 hours at 37° C. in 0.1 M phosphate buffered saline (PBS) at pH 7.4; and (c) the volume fraction of the second polymer phase in the polymer composition is in the range of about 6% to about 40%, based on total volume.