Patent ID: 8685437
Filing Date: 2014-04-01
Classification: A61K,A61P,C08J

Abstract:
1. A process for forming a self-supporting, edible film having a substantially uniform distribution of components comprising at least one anti-emetic compound, said film being dissolvable or disintegrable, comprising the steps of: (a) providing a wet matrix having a uniform distribution of edible components, said components comprising a water-soluble polymer component, an active component comprising at least one anti-emetic compound in the form of particles and water to form an edible matrix with a compositionally uniform distribution of said components; (b) deaerating said matrix by mixing to prevent cavitation of the matrix in a manner which pulls air into the matrix; (c) forming a wet film from said deaerated wet matrix by coating or casting the film; (d) drying said film within about 10 minutes or fewer, wherein said drying step further comprises: (e) dividing said self-supporting film into dosage forms of substantially equal dimensions, wherein each of said dosage forms is compositionally equal, and wherein said dosage forms are each dissolvable or disintegrable in liquid.