Patent ID: 8834879
Filing Date: 2014-09-16
Classification: A61K,A61P,C04B,C07K,C12N

Abstract:
1. A method of treating a fibroproliferative disorder of kidney and/or reducing kidney fibrosis in a mammal in need thereof comprising administering to the mammal a composition comprising a therapeutically effective amount of a zvegf4 antagonist in combination with a pharmaceutically acceptable delivery vehicle, wherein the zvegf4 antagonist is a monoclonal anti-zvegf4 antibody that binds to an epitope of a protein as shown in SEQ ID NO: 2 from amino acid residue 264 to amino acid residue 269, amino acid residue 333 to amino acid residue 355, or amino acid residue 339 to amino acid residue 344.