Patent ID: 6511371
Filing Date: 2003-01-28
Classification: C11D,C12N

Abstract:
An isolated nucleic acid sequence encoding a polypeptide having proteolytic activity, selected from the group consisting of:(a) a nucleic acid sequence encoding a polypeptide having an amino acid sequence which has at least 75% identity with amino acids 1 to 311 of SEQ ID NO: 2; (b) a nucleic acid sequence having at least 70% identity with nucleotides 371 to 1303 of SEQ ID NO: 1; (c) a nucleic acid sequence, which hybridizes under low stringency conditions, wherein low stringency conditions are defined as prehybridization and hybridization at 42Â° C. in 5Ã—SSPE, 0.3% SDS, 200 micrograms/ml sheared and denatured salmon sperm DNA, and 25% formamide, following standard Southern blotting procedures, with the nucleic acid sequence of SEQ ID NO: 1 or its complementary strand; and (d) a subsequence of (a), (b), or (c), wherein the subsequence encodes a polypeptide fragment which has proteolytic activity.