Patent ID: 6599930
Filing Date: 2003-07-29
Classification: A61P,C07D

Abstract:
A compound of the formula I: wherein:R is: A. H, or B. C1-C6-alkyl, C2-C6-alkenyl or C2-C6-alkynyl, wherein alkyl, alkenyl and alkynyl are straight-chain or branched and are optionally substituted once or twice by: B.1 â€”OH, B.2 &boxH;O, B.3 â€”Oâ€”C1-C6-alkyl, in which alkyl is straight-chain or branched, B.4 â€”Oâ€”C2-C6-alkenyl, in which alkenyl is straight-chain or branched, B.5 â€”aryl, B.6 â€”NHâ€”C1-C6-alkyl, in which alkyl is straight-chain or branched, B.7 â€”NHâ€”C2-C6-alkenyl, in which alkenyl is straight-chain or branched, B.8 â€”NH2 or B.9 halogen, in which substituents B.1 to B.9 may be further substituted by â€”CN, amide or oxime functions, R2X2 is OH, R3 is H, R4 is penta-1,3-dienyl, R5 is methyl, X, X3 and X4 are, independently of one another, O, NH, Nâ€”C1-C6-alkyl, Nâ€”C2-C6-alkenyl, Nâ€”C2-C6-alkynyl, wherein alkyl, alkenyl and alkynyl are straight-chain or branched, N-acyl, N-aryl, Nâ€”Oâ€”R or S, or a stereoisomeric form of the compound of formula I, or a physiologically tolerated salt of any of the foregoing.