Patent ID: 6664370
Filing Date: 2003-12-16
Classification: A61K,A61P,C07K,G01N,Y10S

Abstract:
A peptide consisting of the amino acid sequence:Val-Leu-Gly-Val-Val-Phe-Gly-Ile-Leu (Seq. ID No. 11), Leu-Ile-Lys-Arg-Arg-Gln-Gln-Lys-Ile (Seq. ID No. 12); Lys-Ile-Pro-Val-Ala-Ile-Lys-Val-Leu (Seq. ID No. 13); Ile-Leu-Asp-Glu-Ala-Tyr-Val-Met-Ala (Seq. ID No. 14); Gln-Ile-Ala-Lys-Gly-Met-Ser-Tyr-Leu (Seq. ID No. 16); Leu-Leu-Asn-Trp-Cys-Met-Gln-Ile-Ala (Seq. ID No. 17); Arg-Leu-Val-His-Arg-Asp-Leu-Ala-Ala (Seq. ID No. 18); Asp-Ile-Asp-Glu-Thr-Glu-Tyr-His-Ala (Seq. ID No. 19); Thr-Ile-Asp-Val-Tyr-Met-Leu-Met-Val (Seq. ID No. 21); Met-Ile-Met-Val-Lys-Cys-Trp-Met-Ile (Seq. ID No. 22); Gly-Leu-Glu-Pro-Ser-Glu-Glu-Glu-Ala (Seq. ID No. 24); Tyr-Leu-Thr-Pro-Gln-Gly-Gly-Ala-Ala (Seq. ID No. 25); or a peptide of an amino acid sequence of Seq. ID No. 11-14, 16-19, 21, 22, 24 or 25 and up to four amino acids, from the HER-2/neu polypeptide (Seq. ID No. 68) which amino acids are adjacent to the carboxyl terminus of the peptide, are added to the carboxyl terminus of the peptide with or without prior removal of the number of amino acids from the carboxyl terminus equal to the number added.