Patent ID: 8642729
Filing Date: 2014-02-04
Classification: A61K,A61P,C07K

Abstract:
1. A peptide derivative of formula (I): wherein: ζ is hydrogen atom, tyrosine, Y-[linker]- or a Zn chelating group selected from the group consisting of cysteine, C-[linker]-, N-acetyl-cysteine, N-mercaptoacetyl (HS—CH AA AA AA AA AA C-[linker]- meaning Cys-[NH—(CH Y-[linker]- meaning Tyr-[NH—(CH F(X) meaning a phenylalanine, the phenyl group of which is substituted by one or more halogen atoms, S(OAlk) meaning a serine, the hydroxyl group of which is substituted by a linear or branched alkyl group having from 1 to 20 carbon atoms, said AA wherein if the peptide derivative comprises a cysteine, said peptide derivative is optionally a dimer, with the proviso that the peptide is not QRFSR (SEQ ID NO: 1), QRGPR (SEQ ID NO: 9), YQRFSR (SEQ ID NO: 3) or GlpRFSR (SEQ ID NO: 17).