Patent ID: 6962712
Filing Date: 2005-11-08
Classification: A61K,A61P,A61Q

Abstract:
1. A cosmetic or dermatological composition comprising: (i) an N-acylaminoamide inhibitor of elastase, and (ii) at least one compound selected from the group consisting of antifungal agents and antibacterial agents, wherein the inhibitor of elastase is a compound of formula (I):  in which: optionally substituted by 1 to 5 groups, identical or different, selected from —OH; —OR; —O—COR; —SH; —SR, —S—COR; —NH with R and R′ each representing independently a hydrocarbon radical, linear, branched or cyclic, saturated or unsaturated; containing 1 to 6 carbon atoms, optionally halogenated, the R and R′ radicals capable of forming together with N a 5- or 6-membered carbon ring that may include in addition at least one heteroatom selected from O, N and/or S in the ring, and/or may be substituted by 1 to 5 groups, identical or different, selected from —OH; —OR″; —O—COR″; —SH; —SR″; —S—COR″; —NH with R″ representing independently a hydrocarbon radical, linear, branched or cyclic, saturated or unsaturated, containing 1 to 6 carbon atoms, optionally halogenated,; or with R and R′ each representing independently a hydrocarbon radical, linear, branched or cyclic, saturated or unsaturated, containing 1 to 6 carbon atoms, optionally halogenated, the R and R′ radicals capable of forming together with N a 5- or 6-membered carbon ring that may include in addition at least one heteroatom selected from O, N and/or S in the ring, and/or may be substituted by 1 to 5 groups, identical or different, selected from —OH; —OR″; —O—COR″; —SH; —SR′; —S—COR″; —NH optionally substituted by 1 to 5 groups, identical or different, selected from —OH; —OR; —O—COR; —SH; —SR; —S—COR; —NH with R and R′ each representing independently a hydrocarbon radical, linear, branched or cyclic, saturated or unsaturated, containing 1 to 6 carbon atoms, optionally halogenated, the R and R′ radicals capable of forming together with N a 5- or 6-membered carbon ring that may include in addition at least one heteroatom selected from O, N and/or S in the ring, and/or may be substituted by 1 to 5 groups, identical or different, selected from —OH; —OR″; —O—COR″; —SH; —S″; —S—COR″; —NH optionally substituted by 1 to 5 groups, identical or different, selected from —OH; —OR; —O—COR; —SH; —SR; —S—COR; —NH with R and R′ each representing independently a hydrocarbon radical, linear, branched or cyclic, saturated or unsaturated, containing 1 to 6 carbon atoms, optionally halogenated, the R and R′ radicals capable of forming together with N a 5- or 6-membered carbon ring that may include in addition at least one heteroatom selected from O, N and/or S in the ring, and/or may be substituted by 1 to 5 groups, identical or different, selected from —OH; —OR″; —O—COR″; —SH; —SR″; —S—COR″; —NH optionally substituted by 1 to 5 groups, identical or different, selected from —OH; —OR; —O—COR; —SH; —SR; —S—COR; —NH with R and R′ each representing independently a hydrocarbon radical, linear, branched or cyclic, saturated or unsaturated, containing 1 to 6 carbon atoms, optionally halogenated, the R and R′ radicals capable of forming together with N a 5- or 6-membered carbon ring that may include in addition at least one heteroatom selected from O, N and/or S in the ring, and/or may be substituted by 1 to 5 groups, identical or different, selected from —OH; —OR″; —O—COR″; —SH; —SR″; —S—COR″; —NH with R optionally substituted by 1 to 5 groups, identical or different, selected from —OH; —OR; —O—COR; —SH; —SR; —S—COR; —NH with R and R′ each representing independently a hydrocarbon radical, linear, branched or cyclic, saturated or unsaturated, containing 1 to 6 carbon atoms, optionally halogenated, the R and R′ radicals capable of forming together with N a 5- or 6-membered carbon ring that may include in addition at least one heteroatom selected from O, N and/or S in the ring, and/or may be substituted by 1 to 5 groups, identical or different, selected from —OH; —OR″; —O—COR″; —SH; —SR″; —S—COR″; —NH —OH; —OR″; —O—COR″; —SH; —SR″; —S—COR″; —NH