Patent ID: 6242474
Filing Date: 2001-06-05
Classification: C07C,C07D

Abstract:
A pharmaceutical composition which comprises, as an active ingredient, a heterocyclic aromatic ring compound of formula (I): ##STR14##wherein X indicates the substituent represented by formula (II); ##STR15##wherein R.sub.2 represents a lower alkyl group, a lower alkenyl group, a lower alkynyl group, a cyclo-lower alkyl group, an aromatic group, a heterocyclic aromatic group, or a heterocyclic group, each of which may have one or more substituents; ch.sub.1 and ch.sub.2 represent a saturated or unsaturated cross-linking group, which may be branched; ch.sub.1 may have one or more substituents selected from a group consisting of a lower alkyl group, a lower cycloalkyl group, an aromatic group, a heterocyclic group, a lower alkyl-lower cycloalkyl group, an aromatic-lower alkyl group, and a heterocyclic lower alkyl group; Nu represents an imidazole ring; X and Nu may be bonded directly to each other; R.sub.1 represents a hydrogen atom, a halogen atom, a lower alkyl group, an amino group, an acylamino group, a lower alkenyl group, a lower alkynyl group, a halo-lower alkyl group, a lower cycloalkyl group, a nitro group, a lower alkylamino group, a carboxyl group, an esterified carboxyl group, an amidated carboxyl group, a lower alkanesulfonyl group, an aromatic-sulfonyl group, a heterocyclic-aromatic-sulfonyl group, a hydroxyl group, or a lower alkoxyl group; n means a natural number of 2 or less; and A is an aromatic ring that may have one or more substituents; or its pharmaceutically acceptable salt.