Patent ID: 6268185
Filing Date: 2001-07-31
Classification: C12N,C12P,Y10S

Abstract:
A process of converting an .alpha.-amino amide to an .alpha.-amino acid comprising conducting a conversion reaction catalyzed by an amidase enzyme, in which the .alpha.-amino amide starting material comprises amide enantiomers (A) and (B) and in the conversion reaction enantiomer (A) is converted preferentially over enantiomer (B),characterized in that the amidase enzyme is produced by Rhodococcus NCIMB 40795 or Rhodococcus wratslaviensis NCIMB 13082, and in which the amidase enzyme is capable of converting enantiomer (A) such that it gives an enantiomeric excess of at least 90% independently of the conversion time.