Patent ID: 7355063
Filing Date: 2008-04-08
Classification: A61P,C07C,C07D,Y02P

Abstract:
1. A compound represented by the following formula (1): (wherein R 1 is a hydrogen atom, a lower alkyl group, or a protective group of a phenolic hydroxyl group, R 2 is a hydrogen atom or a protective group of a phenolic hydroxyl group, A is an alkylene group having 1 to 4 carbon atoms, B is an alkylene group having 1 to 12 carbon atoms, R 3 is —COOR 4 (wherein R 4 is a protective group of a carboxyl group), a carboxyl group, or —CH 2 OH, and Z is —CO—CH═CH—, —CHOH—CH═CH—, —CHOH—1,2-epoxy-, —CHOH—CH 2 CH 2 —, —CHOH—CH 2 CHOH—, —CO—CH 2 CHOR 5 —, —CHOH—CH 2 CHOR 5 —, a ketal derivative of —CO—CH═CH—, or a ketal derivative of —CO—CH 2 CH 2 — and R 5 is a lower alkyl group when R 3 is a —COOR 4 group, Z is —CO—CH═CH—, —CHOH—CH═CH—, —CHOH—1,2-epoxy-, —CHOH—CH 2 CH 2 —, —CHOH—CH 2 CHOH—, —CO—CH 2 CHOR 5 —, —CHOH—CH 2 CHOR 5 —, a ketal derivative of —CO—CH═CH—, or a ketal derivative of —CO—CH 2 CH 2 — and R 5 is a lower alkyl group when R 3 is a carboxyl group, or Z is —CHOH—CH═CH—, —CHOH—1,2-epoxy-, —CHOH—CH 2 CHOH—,—CO—CH 2 CHOR 5 —, —CHOH—CH 2 CHOR 5 —, a ketal derivative of —CO—CH═CH—, or a ketal derivative of —CO—CH 2 CH 2 — and R 5 is a lower alkyl group when R 3 is a —CH 2 OH).