Patent ID: 8772326
Filing Date: 2014-07-08
Classification: A61K,A61P,C07D

Abstract:
1. A pharmaceutical composition comprising a compound having the structure of Formula (A): a tautomer thereof; or a pharmaceutically acceptable derivative thereof; wherein C=C is cis or trans; A represents an optionally substituted aromatic or non-aromatic 5-6 membered monocyclic ring, optionally containing 1-4 heteroatoms selected from N, O or S; or an optionally substituted aromatic or non-aromatic 8-12 membered bicyclic ring, optionally containing 1-6 heteroatoms selected from N, O or S; q is one or two; and each R is independently selected from the group consisting of hydrogen, halogen, hydroxyl, —NO R R R R in an aqueous buffered saline containing about 40% to about 60% (v/v) polyethylene glycol 300 and about 5% to about 15% polysorbate 80; wherein the compound of Formula A has HGF/SF activity.