Patent ID: 6326014
Filing Date: 2001-12-04
Classification: A61K,A61Q

Abstract:
A skin and/or its exoskeleton, depigmenting or bleaching composition in a form suitable for topical application to the skin and/or its exoskeleton, comprising, in an amount of 0.001 to 10% of the total weight of the composition, of at least one oxamate of formula (I): ##STR2##whereinR represents a hydrogen atom or a radical selected from the group consisting of a hydroxyl radical, a radical --OR', a radical --COR', a radical --COOR', a radical --NR'R"", a radical --CONR'R"", a linear, cyclic or branched, saturated or unsaturated, optionally hydroxylated, C.sub.1 to C.sub.30 aliphatic hydrocarbon radical, and a substituted or unsubstituted aryl radical,R.sub.1 and R.sub.2, which may be identical or different, represent a hydrogen atom or a radical selected from the group consisting of a hydroxyl radical, a radical --OR', a radical --COR', a radical --COOR', a radical --NR'R"", a radical --CONR'R"", a radical --SR', --CH.sub.2 OR', a linear, cyclic or branched, saturated or unsaturated, optionally hydroxylated, C.sub.1 to C.sub.30 aliphatic hydrocarbon radical, and a substituted or unsubstituted aryl radical,wherein R' and R"", which may be identical or different, represent a hydrogen atom, a radical selected from the group consisting of a linear or branched, saturated or unsaturated, optionally hydroxylated, C.sub.1 to C.sub.30 aliphatic hydrocarbon radical, and a substituted or unsubstituted aryl radical, an amino acid residue or a sugar residue,R.sub.3 represents a hydrogen atom or a radical --COOR.sub.4,wherein R.sub.4 represents a linear, cyclic or branched, saturated or unsaturated C.sub.1 to C.sub.30 aliphatic hydrocarbon or alkoxyl radical,X represents a radical selected from the group consisting of a radical --OR.sub.5, a radical --SR.sub.5 and a radical --NR.sub.6 R.sub.7,wherein R.sub.5, R.sub.6 and R.sub.7, which may be identical or different, represent a hydrogen atom, a radical selected from the group consisting of a linear, cyclic or branched, saturated or unsaturated, optionally hydroxylated, C.sub.1 to C.sub.30 aliphatic hydrocarbon radical, and a substituted or unsubstituted aryl radical, an amino acid residue, a peptide residue or a sugar residue;at least one active agent selected from the group consisting of keratolytic agents, desquamating agents, anti-inflammatory agents, calmants, depigmenting agents and mixtures thereof; anda cosmetically or dermatologically acceptable medium.