Patent ID: 6605611
Filing Date: 2003-08-12
Classification: A61P,C07H,G01N

Abstract:
A compound having the structure where X=O or NH or SY=N or CHR6 or CR6 or CO W=N or NR6 or CHR6 or CR6 or S or CO n=2 each R6 is independently H or alkyl or alkenyl or alkoxy or aryl or a reporter moiety, if Y or W=N or CR6, then a double bond is present between the Y and W or between the W and W, and Q is selected from the group consisting of H, a sugar, a sugar analogue, a nucleic acid backbone, and backbone analogue provided that (i) when X is NH and W is CHR6 or CR6, and Y is CO, then at least one R6 is a reporter moiety, (ii) when W is S, then Wn is â€”CHR6â€”Sâ€” or &boxH;CR6â€”Sâ€”, (iii) when X is NH and Y is CHR6 or CR6, then at least one R6 is a reporter moiety that is selected from the group consisting of a reactive group, signal moiety, and solid surface joined to the remainder of the molecule by a linker of at least 3 chain atoms, and (iv) when X is O and Y is CHR6 and W is CHR6 or S, then at least one R6 is a reporter moiety.