Patent ID: 8591875
Filing Date: 2013-11-26
Classification: A61L,C07F,C08G

Abstract:
1. A biocompatible composition comprising: a biodegradable phosphoester polyamine of the following formula: wherein R 1 is selected from the group consisting of polyethers, polyesters, poly(ether-ester) blocks and combinations thereof, R 2 is a hydrogen atom, a protecting group or an organic moiety having from about 1 to about 50 carbon atoms, and NH—R 3 —NH 2 is derived from a polyamine selected from the group consisting of ethylene diamine, hexamethylene diamine, lysine, N-(3-aminopropyl)-1,4-butanediamine, N,N′-bis(3-aminopropyl)-1,4-butanediamine, isomers of hexamethylene diamine, diethylene triamine, triethylene tetramine, tetraethylene pentamine, bishexamethylene triamine, N,N′-bis(3-aminopropyl)-1,2-ethane diamine, N-(3-Aminopropyl)-1,3-propane diamine, N-(2-aminoethyl)-1,3 propane diamine, cyclohexane diamine, isomers of cyclohexane diamine, 4,4′-methylene biscyclohexane amine, 4′4′-methylene bis(2-methylcyclohexanamine), toluene diamine, phenylene diamine, isophorone diamine, phenalkylene polyamines, amino-functionalized polyalkylene oxides, polypeptides, and combinations thereof.