Patent ID: 7045525
Filing Date: 2006-05-16
Classification: A61K,A61P

Abstract:
1. A method of treatment of i) HIV-1 infections in mammals, including humans; or ii) HBV infections in mammals, including humans; which method comprises the administration to the human in need of such treatment, an effective amount of the (R)-enantiomer of the triphosphate of a compound of formula (A): ((R)-PCT-TP), or a pharmaceutically acceptable salt thereof: wherein the (R)-PCV-TP is in the form of a bioprecursor which is a PL-ASOR derivative, phospholipids derivative, (R)-MP Bis(POM) derivative, (R)-MPT diphenyl ester derivative, or dimyristoylglycerol diphosphate derivative of (R)-PCV-MP which liberates intracellularly (R)-PCV-MP which is in turn converted to (R)-PCV-TP.