Patent ID: 6660891
Filing Date: 2003-12-09
Classification: A61K,A61P,C07B,C07C

Abstract:
A method to produce D-chiro-inositol comprising:(a) preparing a reaction solution comprising a crude plant extract comprising a D-chiro-inositol precursor containing a D-chiro-inositol moiety selected from the group consisting of D-chiro-inositol, D-pinitol, ciceritol, 1D-2-O-alpha-D-galactopyranose-chiro-inositol, and fagopyritols in a solution of about 9 N to 12 N HCl; and (b) reacting the solution of step (a) at a temperature in the range of about 65Â° C. to about 110Â° C. for a period of time sufficient to convert the D-chiro-inositol precursor to D-chiro-inositol.