Patent ID: 8124746
Filing Date: 2012-02-28
Classification: C07D,C07H,C09B,C12Q,Y10S,Y10T

Abstract:
1. A kit for fragment analysis comprising one or more nucleoside or nucleotide, a chain-terminating nucleotide analog and a primer, wherein one or more of the nucleoside or nucleotide is a labeled nucleic acid compound comprising the structure: wherein B is a nucleobase; W L is a linkage; wherein if B comprises a purine base, the linkage is attached to the 8-position of the purine, if B comprises a 7-deazapurine base, the linkage is attached to the 7-position of the 7-deazapurine, and if B comprises a pyrimidine base, the linkage is attached to the 5-position of the pyrimidine; and D is an extended rhodamine dye comprising a structure selected from the group consisting of: wherein R R R R R R R R R Y Y Y Y Y Z