Patent ID: 9044450
Filing Date: 2015-06-02
Classification: A61K,A61P

Abstract:
1. An injectable depot formulation, comprising: a biocompatible polymer comprising a copolymer of lactic acid and glycolic acid, wherein the biocompatible polymer has a number average molecular weight ranging from 1000 Daltons to 5000 Daltons; an organic solvent combined with the biocompatible polymer to form a viscous gel, the organic solvent being selected from benzyl alcohol, benzyl benzoate, ethyl benzoate, ethyl hydroxide, N-methyl-2-pyrrolidone, and mixtures thereof; and a drug selected from base and salt forms of risperidone in particle form incorporated in the viscous gel, wherein the particles have a particle size less than 38 μm, and wherein the salt forms of risperidone have less than 1 mg/mL solubility in water.