Patent ID: 6046215
Filing Date: 2000-04-04
Classification: A61P,C07D

Abstract:
A compound of Formula II: ##STR13## A--B is --C.dbd.CH--; R.sup.1 is H, halo, formyl, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, 4,5-dihydrothiazol-2-yl, cyano, nitro, carboxamido, trifluoromethyl or hydroxy;R.sup.2 is H or halo;R.sup.3 is H, C.sub.1 -C.sub.4 alkyl, (C.sub.1 -C.sub.4 alkylene)-aryl, or --CH.sub.2 --Y--NR.sup.7 R.sup.8 ;R.sup.6 is H or methyl;Y is --CH.sub.2 -- or --C(O)--;R.sup.7 is pyridinyl; andR.sup.8 is H or --C(O)--(C.sub.3 -C.sub.6 cycloalkyl), provided that R.sup.1 and R.sup.2 may not both be H, and R.sup.1 may not be C.sub.1 -C.sub.4 alkyl when R.sup.2 is H, or pharmaceutically acceptable salts or hydrates thereof.