Patent ID: 8202690
Filing Date: 2012-06-19
Classification: A61K,A61P,C12Q,G01N

Abstract:
1. A method for detecting cancer in a specimen suspected of cancer, comprising: measuring a level of BCH motif-containing molecule at the carboxyl terminal region 1 gene expression in the specimen suspected of cancer; comparing the level of BCH motif-containing molecule at the carboxyl terminal region 1 gene expression in the specimen suspected of cancer with a level of BCH motif-containing molecule at the carboxyl terminal region 1 gene expression in a normal specimen and a level of BCH motif-containing molecule at the carboxyl terminal region 1 gene expression in a cancer specimen; comparing the level of Differential Display Code 3 gene expression in the specimen suspected of cancer with a level of Differential Display Code 3 gene expression in a normal specimen and a level of Differential Display Code 3 gene expression in a cancer specimen; and determining the specimen suspected of cancer is cancerous when: the level of BCH motif-containing molecule at the carboxyl terminal region 1 gene expression in the specimen suspected of cancer is either (i) lower than the level of BCH motif-containing molecule at the carboxyl terminal region 1 gene expression in the normal specimen, (ii) the same level as the level of BCH motif-containing molecule at the carboxyl terminal region 1 gene expression in the cancer specimen, or, both (i) and (ii); and the level of Differential Display Code 3 gene expression in the specimen suspected of cancer is either (i) higher than the level of Differential Display Code 3 gene expression in the normal specimen, (ii) the same level as the level of Differential Display Code 3 gene expression in the cancer specimen, or, both (i) and (ii); wherein the cancer is prostate cancer.