Patent ID: 9144563
Filing Date: 2015-09-29
Classification: A61K,A61P

Abstract:
1. A method of treating breast cancer comprising administering a therapeutically effective amount of a combination of formulations to a human patient, wherein the formulations include (a) a formulation comprising a cationic liposomal preparation comprising at least one cationic lipid from about 30 mole % to about 99.9 mole %, a taxane in an amount of at least about 0.1 mole %, and at least one neutral lipid from about 30 mole % to about 70 mole %, wherein the liposomal preparation has a zeta potential in the range of about 0 mV to about 100 mV in about 0.05 mM KCl solution at about pH 7.5; and (b) a formulation comprising a non-liposomal preparation comprising a taxane; and wherein the formulation comprising the cationic liposomal preparation is administered in a single dose of between about 1 mg/m