Patent ID: 6319933
Filing Date: 2001-11-20
Classification: A61P,C07D

Abstract:
A compound of the formula, ##STR17##whereinQ is a phenyl ring which is unsubstituted or substituted by 1 to 3 halogen atom(s);R is hydrogen, hydroxy, carboxy, carbamoyl, cyano, lower-alkyl, lower-alkoxycarbonyl or lower-alkoxy, wherein said lower-alkyl, lower-alkoxycarbonyl and lower-alkoxy is unsubstitued or substituted by one or more halogen, lower-alkyl, di-lower-alkylamino or lower-alkoxy;X is a 5 or 6 membered hetero-aromatic ring;Y is phenyl or pyridyl, each of which is unsubstitued or substituted by one or more halogen, cyano, lower-alkyl, di-lower-alkylamino, lower-alkyloxy, acyl, lower-alkoxycarbonyl; andZ is a sulfur and nitrogen containing 5 membered hetero-aromatic ring; or pharmaceutically acceptable salts thereof.