Patent ID: 6252075
Filing Date: 2001-06-26
Classification: C07D

Abstract:
A process for producing a compound represented by the formula (5): ##STR13##whereinR.sup.1 is a hydrogen atom, a hydroxyl group, a C.sub.1 -C.sub.8 saturated or unsaturated alkoxy group, a C.sub.1 -C.sub.8 saturated or unsaturated acyloxy group, a siloxy group, a fluorine atom, a chlorine atom, a bromine atom, an iodine atom, an amino group, an amino group protected with one or two C.sub.1 -C.sub.8 acyl groups, a C.sub.1 -C.sub.10 alkoxycarbonylamino group, an aryloxycarbonyl amino group, an unsubstituted benzyloxycarbonylamino group, a substituted benzyloxycarbonylamino group, or a C.sub.1 -C.sub.8 saturated or unsaturated alkyl group,R.sup.2 is a hydrogen atom, a hydroxyl group, a C.sub.1 -C.sub.8 saturated or unsaturated alkoxy group, a C.sub.1 -C.sub.8 saturated or unsaturated acyloxy group, a siloxy group, a fluorine atom, a chlorine atom, a bromine atom, an iodine atom, an amino group, an amino group protected with one or two C.sub.1 -C.sub.8 acyl groups, a C.sub.1 -C.sub.10 alkoxycarbonylamino group, an aryloxycarbonylamino group, an unsubstituted benzyloxycarbonylamino group, a substituted benzyloxycarbonylamino group or a C.sub.1 -C.sub.8 saturated or unsaturated alkyl group,R.sup.3 is a hydrogen atom, a C.sub.1 -C.sub.6 alkyl group, a C.sub.1 -C.sub.6 alkoxy group, a hydroxyl group, a nitro group, an amino group, a sulfonic acid group, a carboxyl group, a C.sub.1 -C.sub.6 alkoxycarbonyl group, a fluorine atom, a chlorine atom, a bromine atom, or an iodine atom, andR.sup.4 and R.sup.5 are each, independently, a hydrogen atom, a C.sub.1 -C.sub.20 linear or branched saturated or unsaturated alkyl group, a C.sub.1 -C.sub.20 alkoxy group, a C.sub.1 -C.sub.10 acyl group, a C.sub.1 -C.sub.10 acyloxy group, a carboxyl group, or a C.sub.1 -C.sub.10 alkoxycarbonyl group, orR.sup.4 and R.sup.5, together with the carbon atom they are bonded to, form a 3- to 8-membered ring, wherein the ring members are all carbon atoms, or alternatively said ring contains 1, 2 or 3 heteroatoms selected from the group consisting of N, O or S,wherein said acyl group is RC(O)--, wherein R is hydrocarbylcomprising reacting a 7-benzylpurine derivative represented by formula (2), or a salt thereof: ##STR14##wherein R.sup.1, R.sup.2 and R.sup.3 are as defined above,with a compound represented by formula (4): ##STR15##wherein R.sup.4 and R.sup.5 are as defined above.