Patent ID: 6753011
Filing Date: 2004-06-22
Classification: A61K

Abstract:
A device for the controlled delivery of at least one active agent to an environment of use, wherein the device comprises:a core expandable in a fluid from the environment of use, the core being approximately centrally located in the device; a layer comprising at least one first active agent, wherein the layer is in contact with and surrounds the core; and a membrane in contact with and surrounding the layer and comprising at least one preformed passageway for delivery of the at least one active agent by osmotic pumping and plural micropores for delivery of the at least one active agent by diffusion, and the membrane further comprising one or more cellulose esters, one or more poly(methacrylate) copolymer salts and one or more plasticizers, wherein the membrane permits delivery of the at least one active substance through a combination of diffusion and osmotic pumping.