Patent ID: 7465743
Filing Date: 2008-12-16
Classification: A61P,C07D

Abstract:
1. A compound of formula (I) or a salt thereof: wherein: R R NHR  wherein, in sub-formula (nhr3), the —NH— connection point of the NHR R R R R R provided that: (a) R and provided that: (c) when R and wherein: R or R or R or R or R  wherein in sub-formula (x), n=0, 1 or 2; in sub-formula (y) and (y1), m=1 or 2; and in sub-formula (z), r=0, 1 or 2; wherein sub-formula (y) and (y1), independently, are optionally substituted by oxo at a ring carbon adjacent the 6-membered aromatic ring; and wherein, in sub-formula (xa) and (za): R R or R or R or R or R or R or R provided that at least one of R and wherein, in sub-formula (x) and in sub-formula (xa): A is C—R B is C—R D is C—R E is C—R F is C—R wherein, R and two adjacent groups are selected from the group consisting of R provided that: at least two of A, B, D, E and F are independently C—H, C—F, nitrogen, or nitrogen-oxide; and no more than two of A, B, D, E and F are independently nitrogen or nitrogen-oxide, and no more than one of A, B, D, E and F is nitrogen-oxide; and wherein, in sub-formula (z) and in sub-formula (za): G is O or S or NR J is C—R L is C—R M is C—R Q is C—R wherein, R provided that: at least two of J, L, M and Q are independently C—H, C—F, C—C and no more than three of J, L, M and Q are nitrogen; and wherein: R or R R R R or R R R R R R R R Ar Het