Patent ID: 8535709
Filing Date: 2013-09-17
Classification: A61K,A61L

Abstract:
1. A therapeutic formulation adapted for positive-pressure application and effective for controlling biological fluid at a desired site in a subject, the formulation comprising: (i) about 25% to about 99% by weight liquid-crystal forming compound, which is a fatty acid ester selected from the group consisting of glyceryl monoarachidonate, glyceryl monolinoleate, glyceryl monolinolenate, glyceryl monopalmitoleate, glyceryl monooleate, glyceryl monoerucate, propylene glycyl monoarachidonate, propylene glycyl monolinoleate, propylene glycyl monolinolenate, propylene glycyl monopalmitoleate, propylene glycyl monooleate, and combinations thereof; (ii) solvent; and (iii) a fatty acid combination selected from the group consisting of caprylic acid, capric acid, lauric acid, myristic acid, myristoleic acid, palmitic acid, palmitoleic acid, oleic acid, and pharmaceutically acceptable salts thereof; wherein the formulation effectively controls biological fluid at the desired site in the subject by being in a liquid crystalline state or capable of forming a liquid crystalline state after application to the desired site.