Patent ID: 8097653
Filing Date: 2012-01-17
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A method for relieving constipation in a human patient in need of relief of constipation that comprises administering to the patient a dosage unit comprising (i) 24 μg+/−10% of a PG analog represented by Formula (I) and/or its tautomer and (ii) a pharmaceutically suitable excipient: where A 1 and A 2 are fluorine atoms and B is —COOH, including its pharmaceutically acceptable salts, esters or amides, to thereby relieve constipation in the patient, wherein said dosage unit is administered enough times per day so that the total daily dose of the PG analog is in the range of about 48-72 μg.