Patent ID: 6391316
Filing Date: 2002-05-21
Classification: A61K,C07K

Abstract:
A vaccine composition comprising a pharmaceutically acceptable vehicle and an isolated immunogenic H. somnus transferrin-binding protein selected from the group consisting of (a) an H. somnus transferrin-binding protein 1 having at least about 90% sequence identity to the contiguous sequence of amino acids shown at amino acid positions 1-971, inclusive, of FIG. 3 (SEQ ID NO:2), (b) an H. somnus transferrin-binding protein 1 having at least about 90% sequence identity to the contiguous sequence of amino acids shown at amino acid positions 29-971, inclusive, of FIG. 3 (SEQ ID NO:2), (c) an H. somnus transferrin-binding protein 2 having at least about 90% sequence identity to the contiguous sequence of amino acids shown at amino acid positions 1-662, inclusive, of FIG. 4 (SEQ ID NO:3), and (d) an H. somnus transferrin-binding protein 2 having at least about 90% sequence identity to the contiguous sequence of amino acids shown at amino acid positions 20-662, inclusive, of FIG. 4 (SEQ ID NO:3).