Patent ID: 6117998
Filing Date: 2000-09-12
Classification: A61P,C07D

Abstract:
An assay-type probe of a compound of the formula: ##STR11## wherein R.sub.1 is selected from the group consisting of C.sub.1 -C.sub.8 alkyl;R.sub.2 is of the formula: ##STR12## wherein n is an integer ranging from 1 to 8; R.sub.5 is H or CH.sub.3 (CH.sub.2).sub.p, wherein p is an integer ranging from 1 to 7; and R.sub.6 is H or (CH.sub.2).sub.m OH, wherein m is an integer ranging from 1 to 8;R.sub.3 is of the formula:--(CH.sub.2).sub.q C.sub.6 H.sub.4 --R.sub.7andwherein q is an integer ranging from 1 to 8; and wherein R.sub.7 is selected from the group consisting of H, NH.sub.2, R.sub.9 COOH, wherein R.sub.9 is an alkylene or alkenylene group having 1 to 8 carbon atoms, and (CH.sub.2).sub.t OH, wherein t is an integer ranging from 1 to 8; andR.sub.4 is of the formula: ##STR13## wherein R.sub.8 is selected from the group consisting of H; NH.sub.2 ; (CH.sub.2).sub.s OH, wherein s is an integer ranging from 1 to 8; and R.sub.10 COOH, wherein R.sub.10 is an alkylene or alkenylene group having 1 to 8 carbon atoms; and r is an integer ranging from 1 to 8;wherein said assay-type probe is labeled with biotin.