Patent ID: 8558048
Filing Date: 2013-10-15
Classification: A61K,A61P,C07K,C12N,C12Y,Y10S

Abstract:
1. A formulation, said formulation comprising: (a) a protein crystal, and (b) at least one excipient selected from the group consisting of sucrose, trehalose, lactitol, gelatin, hydroxypropyl-β-cyclodextrin, and methoxypolyethylene glycol, wherein the amount of methoxypolyethylene glycol in the formulation does not exceed 30% W/W, and wherein said formulation is characterized by at least a 60 fold greater shelf life when stored at 40° C. to 55° C. than the soluble form of said protein in solution 40° C. to 55° C., as measured by T