Patent ID: 7749991
Filing Date: 2010-07-06
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A therapeutic method for the treatment of fungal or bacterial pathological conditions, which comprises administering to a subject in a need of such a treatment a therapeutically effective amount of a pharmaceutical composition containing as active ingredient a compound of general formula (I) or a conjugate of a compound of general formula (I) with a macromolecule selected from the group consisting of aminoacids, polypeptides, proteins and polysaccharides, optionally in combination with pharmaceutically acceptable excipients, in which general formula (I): M is selected from the group consisting of Zn, Si(OR R is H or a group selected from alkyl, alkenyl and alkyloxy group, linear or branched, having from 1 to 10 carbon atoms provided that, when R is different from H, the positions 8, 11, 15, 18, 22, 25 or 9, 10, 16, 17, 23, 24 are substituted; and R where: Y is selected from the group consisting of C1-C10 alkyl and phenyl, optionally substituted, or it forms with the Z group, to which it is bound, a saturated or unsaturated heterocycle, optionally substituted, which may contain up to two heteroatoms selected from the group consisting of N, O and S; Z is selected from the group consisting of —N, —CH R R m, n, p, w, t and u, independently from one another, are 0 or 1; and v is an integer between 1 and 3, provided that when R R