Patent ID: 8771743
Filing Date: 2014-07-08
Classification: A61K,A61P,A61Q

Abstract:
1. A multi-layered lamellar granule comprising: a nucleating agent particle; and a ceramide-containing artificial stratum corneum lipid layer, said artificial stratum corneum lipid layer having a multi-layered lamellar structure that is spray-coated on the nucleating agent particle and embeds the nucleating agent particle in the multi-layered lamellar structure, wherein an outer surface of the multi-layered lamellar granule of the artificial stratum corneum lipid lamellar layer and the nucleating agent particle is spray-coated with a polymer layer; and wherein the nucleating agent particle is a particle made of the substance selected from the group consisting of sugar, a salt, hyaluronic acid, alginic acid, chondroitin sulfate, chitosan, chitin, polylysine, collagen, gelatin, stearic acid, cetyl alcohol, stearyl alcohol, and a mixture thereof.