Patent ID: 8778303
Filing Date: 2014-07-15
Classification: A61K

Abstract:
1. A radiopharmaceutical compound comprising: (a) a polypeptide sequence set forth in SEQ ID NO:1 or a sequence having at least 70% sequence similarity to SEQ ID NO:1, wherein the polypeptide comprises a covalent bond between amino acids located at positions 1 and 18, 4 and 14, and 5 and 11 and further comprises a covalent bond between amino acids located at positions 6 and 19; (b) a radioisotope consisting of (c) a chelation moiety wherein the chelation moiety is covalently or non-covalently bonded to the polypeptide and is chelated with the radioisotope, or a chemical intermediate wherein the radioisotope is part of the chemical intermediate, and wherein the chemical intermediate is covalently or non-covalently bonded to the polypeptide; or, a salt or hydrate thereof.