Patent ID: 6423734
Filing Date: 2002-07-23
Classification: A61K,A61P

Abstract:
A method of preventing cancer or inhibiting metastasis of cancer susceptible to treatment in a subject at risk for developing cancer or metastasis of cancer comprising administering to said subject in need thereof a pharmaceutical composition comprising a therapeutically effective amount of a benzimidazole having the formula: wherein,X is hydrogen, halogen, alkyl of less than 7 carbon atoms, or alkoxy of less than 7 carbon atoms; n is a positive integer of less than 4; Y is hydrogen, chlorine, nitro, methyl, or ethyl; R is hydrogen or an alkyl group having from 1 to 8 carbon atoms; and R2 is 4-thiazolyl or NHCOOR1 wherein R1 is an aliphatic hydrocarbon of less than 7 carbon atoms.