Patent ID: 9198645
Filing Date: 2015-12-01
Classification: A61B,A61K

Abstract:
1. A method for producing a liposome-containing composition, which comprises: providing a solvent stream of a composition of lipids or lipid-forming materials dissolved in a water-miscible solvent through a central microchannel having a hydrodynamic diameter of 100 μm or less, and impinging on said solvent stream through at least one side microchannel at least one aqueous stream of an aqueous composition which hydrodynamically focuses the solvent stream and forms, under laminar flow conditions, a solvent stream and an aqueous stream within the central microchannel having an interfacial region between them where the solvent stream and the at least one aqueous stream diffuse into each other providing conditions where liposomes self-assemble from the lipids or lipid-forming materials to form a lipsome-containing composition with liposomes having a mean diameter of from 100 nm to 300 nm and a size distribution of 20% or less.