Patent ID: 7557114
Filing Date: 2009-07-07
Classification: A61P,C07D

Abstract:
1. A compound of formula I wherein R R R is an aromatic or partially aromatic bicyclic amine, having one or two additional N-atoms selected from the group consisting of and wherein one additional N-ring atom of the aromatic or partially aromatic bicyclic amine can be available in form of its oxide R R and R′, are each independently hydrogen or lower alkyl; wherein heteroaryl is selected from the group consisting of furanyl, thienyl, pyrrolyl, imidazolyl, pyrazolyl, triazolyl, thiazolyl, isothiazolyl, isoxazolyl, pyridinyl, pyrazinyl, and pyrimidinyl; and heterocycloalkyl is selected from the group consisting of tetrahydropyran-2, 3 or 4-yl, tetrahydrofuran-2 or 3-yl, oxetan-3-yl, and [1,4]dioxin-2-yl; and wherein all aryl-, morpholin, heterocycloalkyl- or 5 or 6 membered heteroaryl groups as defined for R n, m, o, p, q, r, s and t are each independently 1 or 2; x is 0, 1 or 2; and y is 1 or 2; or a pharmaceutically acceptable acid addition salt thereof.