Patent ID: 8663638
Filing Date: 2014-03-04
Classification: A61K,A61P,C07K

Abstract:
1. A method for destroying tumor cells, the method comprising: Administering directly and locally into a human patient's abdominal cavity, during surgical removal of a tumor located in the patient's abdominal cavity, a pharmaceutical composition comprising a trifunctional, bispecific and/or trispecific antibody, wherein the trifunctional, bispecific and/or trispecific antibody binds to a T cell via CD3; binds to at least one tumor-associated antigen which is expressed on the tumor cells; and binds by its Fc part (in the case of bispecific antibodies) or by a third specificity (in the case of trispecific antibodies) to Fc receptor-positive cells, wherein the antibody is administered in an amount of about 1 to about 400 μg.