Patent ID: 8399402
Filing Date: 2013-03-19
Classification: C07K,G01N

Abstract:
1. A polypeptide as standard for peptide analysis by mass spectrometry comprising at least 16 peptide sequences, at least 18 peptide sequences, at least 20 peptide sequences, or at least 22 peptide sequences selected from the group consisting of the peptide sequences VFDEFKPLVEEPQNLIR (SEQ ID NO: 1), VFDEFKPLVKPEEPQNLIR (SEQ ID NO: 2), VFDEFKPLVKPEEKPQNLIR (SEQ ID NO: 3), FDEFKPLVKPEEKPQNKPLIR (SEQ ID NO: 4), VFKPDEFKPLVKPEEKPQNKPLIR (SEQ ID NO: 5), VFKPDEFKPLVKPEEKPQNKPLIKPR (SEQ ID NO: 6), VFDEFQPLVEEPQNLIR (SEQ ID NO: 7), GVNDNEEGFFSAR (SEQ ID NO: 8), GGVNDNEEGFFSAR (SEQ ID NO: 9), GGGVNDNEEGFFSAR (SEQ ID NO: 10), GVNDNEEGFFSAK (SEQ ID NO: 11), AVMDDFAAFVEK (SEQ ID NO: 12), AVMMDDFAAFVEK (SEQ ID NO: 13), AVMMMDDFAAFVEK (SEQ ID NO: 14), GLVK (SEQ ID NO: 15), FVVPR (SEQ ID NO: 16), ALELFR (SEQ ID NO: 17), IGDYAGIK (SEQ ID NO: 18), EALDFFAR (SEQ ID NO: 19), YLGYLEQLLR (SEQ ID NO: 20), VLYPNDNFFEGK (SEQ ID NO: 21), LFTFHADICTLPDTEK (SEQ ID NO: 22), and/or functional variants thereof having conservative amino acid substitutions and/or substitution of aromatic amino acids with another aromatic amino acid.