Patent ID: 6410247
Filing Date: 2002-06-25
Classification: C07K,G01N,Y10S

Abstract:
A method for detecting the presence of a cancer in an individual, the method comprising the steps of:(a) contacting a body fluid sample from the individual with a first binding partner and a second binding partner that bind specifically to a body fluid-soluble interior nuclear matrix protein, wherein the first binding partner is labeled with a detectable label and the second binding partner is immobilized on a solid support, such that the body fluid-soluble interior nuclear matrix protein, if present in the fluid sample, produces an amount of labeled complex immobilized on the solid support comprising the first binding partner, the body fluid-soluble interior nuclear matrix protein, and the second binding partner; and (b) determining whether the amount of the labeled complex immobilized on the solid support is greater than a known standard, wherein an amount of labeled complex greater than the known standard is indicative of the presence of the cancer in the individual.