Patent ID: 6153645
Filing Date: 2000-11-28
Classification: C07D

Abstract:
A compound of the Formula: ##STR35## (a) wherein each of R.sup.1 and R.sup.2 is independently selected from the group consisting of aryl and heteroaryl;(b) wherein A is selected from the group consisting of ##STR36## wherein R.sup.3 is selected from the group consisting of hydrido, alkyl, carboalkoxy, and carboxyamido;(c) wherein each of X and Y is independently selected from the group consisting of CH and N;(d) wherein Z is selected from the group consisting of ##STR37## (e) wherein M is selected from the group consisting of hydrido, alkyl, aryl, carboxy and carboalkoxy;(f) wherein D is selected from the group consisting of hydrido, aryl, heteroaryl, and alkyl; alternatively, M and D together are selected from the group consisting of ##STR38## wherein each of R.sup.9, R.sup.10, R.sup.11, and R.sup.12 is independently selected from the group consisting of hydrido, halo, aLkoxy and alkyl; wherein E is selected from the group consisting of hydrido, hydroxy, alkoxy, aryloxy, halo and amino; wherein V and W are independently selected fom the group consisting of ##STR39## wherein B is selected from the group consisting of ##STR40## wherein each of R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.13, and R.sup.14 is independently selected from the group consisting of alkyl and hydrido; and pharmaceutically-acceptable salts thereof.