Patent ID: 8951980
Filing Date: 2015-02-10
Classification: A61K,A61P,C12N

Abstract:
1. A method of treating or preventing non-alcoholic fatty liver disease in an individual, said method comprising administering to the patient a therapeutically effective amount of Adenovirus-36 E4orf1 protein, wherein said protein is SEQ ID NO: 2, SEQ ID NO:4 or functional variant thereof, wherein said functional variant has at least 85% sequence identity to SEQ ID NO:2 or SEQ ID NO:4, or a nucleic acid encoding Adenovirus-36 E4orf1, wherein said nucleic acid is SEQ ID NO:1 or SEQ ID NO:3 or functional variant thereof, wherein said functional variant has at least 85% sequence identity to SEQ ID NO:1 or SEQ ID NO:4, or an analog of Adenovirus-36 E4orf1, wherein the patient's symptoms improve following said administration.