Patent ID: 6673816
Filing Date: 2004-01-06
Classification: A61P,C07D

Abstract:
A method of treating a metabolic bone disorder in a subject in need of such treatment comprising administering to said subject an effective amount of a compound of general formula (I) in whichm signifies a number between 0-8, and q signifies a number between 0-8, wherein m and q are not both 0, a signifies a number between 0-4, A signifies a single or double bond, R1,R2 signify hydrogen or lower alkyl, whereby R1,R2 are the same or different and, when m signifies 2-8, R1 and R2 in the group CR1&boxH;CR2 optionally have various significances within the following sequence, R3 signifies hydrogen or lower alkyl, X signifies hydrogen or â€”(CH2)bâ€”COR4 with b=0-4, Y signifies hydrogen, â€”COR4, phenyl or indolyl residue R4 signifies hydroxyl, lower alkoxy or the NR1R2 residue, whereby R1 and R2 are the same or different, and W signifies an optionally mono- or polysubstituted saturated or unsaturated mono-, bi- or tricycle which optionally contain one or more hetero atoms, wherein W is not phenyl or indolyl, if m and a are both O, R3 is hydrogen and A is a double bond, or a physiologically compatible salt, ester, optically active form, racemate, tautomer or prodrug thereof.