Patent ID: 6635680
Filing Date: 2003-10-21
Classification: A61K,A61P,Y10S

Abstract:
A composition comprising a core element containing a therapeutically effective amount of a solid medicament and a coating composition on said core element which coating composition comprises a mixture comprising:(a) at least 75% by weight of a water insoluble polymer in a latex dispersion in water, said water insoluble polymer being insoluble in both acidic as well as basic pH; and (b) 1 to 25% by weight of an enteric polymer which is substantially insoluble in water at a pH below 4.5 and which is substantially soluble in water at a pH above about 6.0, said enteric polymer and said water insoluble polymer being present in an amount effective to control the release of said medicament from the pharmaceutical composition when placed in an aqueous media, said mixture being heterogeneous, wherein the sum of the percentages of said water insoluble polymer and said enteric polymer is equal to or less than 100%.