Patent ID: 8735388
Filing Date: 2014-05-27
Classification: A61K,A61P,C07D,C07F

Abstract:
1. A heterocyclic compound of the formula (I) or a pharmaceutically acceptable salt thereof, wherein the heterocycle comprises two double bonds, which may be present at varying positions, and which are represented by the dashed lines (---);  if Y is O, X1 is CH and X2 is CZ—R2 or C—R3, wherein Z is NH, O, or S; and  if Y is CH or NH, one of X1 and X2 is CH or N, wherein if X1 is CH or N, X2 is C—Z—R2 or C—R3, and if X2 is CH or N, X1 is C—Z—R2 or C—R3, wherein Z is NH or S; R1 is structure (c): R2 is chosen from (C R3 is chosen from (C and optionally, when R2 is an unbranched (C or a pharmaceutically acceptable salt thereof, through the X 1 a or X 2 a of formula (Ia), wherein if X 1 is CH or N, X 1 a is CH or N and X 2 a is C—Za-, or if X1 is C—Z—R2, X 1 a is C—Za- and X 2 a is CH or N, wherein X 1 a or X 2 a having Za links to R2; wherein Wa is N or NH; Ya is CH, O or NH; Za is NH, O, or S; and R