Patent ID: 9011876
Filing Date: 2015-04-21
Classification: A61K,A61P,C07K,C12N

Abstract:
1. A live, attenuated respiratory syncytial virus (RSV) comprising a viral genome, wherein the viral genome encodes proteins that comprise a glutamic acid at position 204 of the protein encoded by the G gene; a glutamic acid at position 205 of the protein encoded by the G gene; an alanine at position 211 of the protein encoded by the G gene; a glutamic acid at position 213 of the protein encoded by the G gene; a glycine at position 221 of the protein encoded by the G gene; a glycine at position 223 of the protein encoded by the G gene; a glycine at position 232 of the protein encoded by the G gene; a glycine at position 486 of the protein encoded by the F gene; and an alanine at position 148 of the protein encoded by the L gene.