Patent ID: 6441184
Filing Date: 2002-08-27
Classification: A61P,C07D

Abstract:
A compound selected from the group consisting of an amide of formula: and a pharmaceutically acceptable salt thereof;whereinR1 is an alkyl having from 1 to 3 carbon atoms; R2 is hydrogen, halo, nitro, cyano, or perfluoro-methyl; R3 is a cycloalkyl having from 4 to 7 carbon atoms or 2-propyl; Z is â€”CH2â€”CH2â€”CH2â€”CH2â€” or â€”CH&boxH;CR4â€”CH&boxH;CHâ€”, wherein R4 is hydrogen, halo, or an alkyl sulfone having from 1 to 3 carbon atoms; W is O, S or NH; and * denotes an asymmetric carbon.