Patent ID: 7799560
Filing Date: 2010-09-21
Classification: C12M

Abstract:
1. A compartmentalized roller bottle device comprising: a device housing having a longitudinal axis, at least a portion of said device housing including structural means to roll on a roller rack; a basal medium compartment having a longitudinal axis residing within said device housing, said basal medium compartment having a sidewall of which at least a portion is comprised of a semi-permeable, non-microporous membrane; said basal medium compartment including a rigid structure for maintaining the longitudinal axis of said basal medium compartment in the same direction as said longitudinal axis of said device housing when liquid resides within said basal medium compartment; the space within said device housing that is not occupied by said basal medium compartment forming a cell culture compartment; a first access port providing fluid access to said basal medium compartment; a second access port providing fluid access to said cell culture compartment, and a means of providing gas exchange between said cell culture compartment and ambient gas other than by requiring gas to only enter said cell culture compartment by traversing said semi-permeable membrane of said basal medium compartment.