Patent ID: 8133688
Filing Date: 2012-03-13
Classification: A61P,C07K,G01N

Abstract:
1. A method of indicating the presence of a factor in a biological sample of a rheumatoid arthritis patient that inhibits the binding of an antibody or fragment thereof, which is specific for denatured human serum albumin comprising: providing a biological sample from a patient; contacting said biological sample with an antibody or fragment thereof, which is specific for denatured human serum albumin; contacting said biological sample and said antibody or fragment thereof with denatured human serum albumin; and detecting the amount of binding of said antibody or fragment thereof to said denatured human serum albumin, wherein an inhibition in binding of said antibody or fragment thereof to said denatured human serum albumin indicates the presence of said factor in said biological sample.