Patent ID: 8846698
Filing Date: 2014-09-30
Classification: A61K,A61P,C07D

Abstract:
1. A compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein R R R R X is a bond, O, (CH—R R R n is 1 or 2; R R R R wherein the bicyclic ring system can be 2 rings (carbocyclic-carbocyclic, carbocyclic-heterocyclic, heterocyclic-carbocyclic or heterocyclic-heterocyclic) fused or linked by a single bond, which ring system is optionally substituted by up to 3 substituents independently selected from, where possible -halo, CN, NR 5 R 6 , SO 2 R 7 , SR 7 , C 1-4 alkyl optionally substituted by up to 3 OH and/or C 1-3 alkoxy groups, C 3-6 cycloalkyl optionally substituted by up to 3 OH and/or C 1-3 alkoxy groups, C 1-3 alkyl substituted by 1 to 3 halogen, OH, O(C 1-3 alkyl), O(C 3-6 cycloalkyl optionally substituted by up to 3 OH and/or C 1-3 alkoxy groups, O(C 1-3 alkyl substituted by up to 3 halogen, O(C 1-3 alkyl substituted by up to 3 OH and/or C 1-3 alkoxy, NR 5 SO 2 R 7 , ═O, NO 2 , NR 7 COR 7 ,NR 5 CO 2 R 7 , and S(O)R 7 ; R wherein each CH moiety can be replaced by a CF moiety.