Patent ID: 6727269
Filing Date: 2004-04-27
Classification: A61P,C07D,C40B

Abstract:
A compound of the formula (I) in racemic, enantiomeric form or any combination of these forms, in which:R1 is selected from the group consisting of an amino (C2-C7)alkyl, aminoalkylarylalkyll, aminoalkylcycloalkylalkyl, (C1-C-15)alkyl, (C3-C7)cycloalkyl, (C1-C6)alkyl(C3-C6)cycloalkyl, (C3-C6)cycalkylalkyl, R2 represents an optionally substituted carbocyclic aryl consisting of a system of rings at least one of which is aromatic or R2 represents one of the radicals represented below: R3 represents a linear or branched alkyl radical containing 1 to 6 carbon atoms or R3 represents an optionally substituted carbocyclic aryl radical, said carbocyclic aryl radical consisting of a system of rings at least one of which is aromatic, or R3 is R4 is H or alkyl of 1 to 6 carbon atoms, i)for R2, when the group is substituted, it is substituted 1 to 5 times (apart from the bond which connects it to the rest of the molecule) by at least one member of the group consisting of halogen, alkyl of 1 to 6 atoms, linear or branched alkoxy containing 1 to 6 carbon atoms, linear or branched alkythio of 1 to 6 carbon atoms, haloalkyl of 1 to 6 carbon atoms alkenyl, haloalkoxy of 1 to 6 carbon atoms, nitro, cyano, azido, So2N, mono- or di-alkylamino the alkyl of which have 1 to 6 carbon atoms, aminoalkyl alkyl of which has 1 to 6 carbon atoms, aralkoxy of which the araloxy has 1 to 6 carbon atoms, or aryl, which two substituents can, if appropriate, be connected together and form a ring, ii) for R3, when aryl group(s) (originating from an aryl or aralkyl) is the carbocyclic aryl or aralkyl radicals have 1 to 5 substituents selected from the group consisting of a halogen, alkyl of 1 to 6 carbon atoms, hydroxy, alkoxy of 1 to 6 carbon atoms, haloalkyl of 1 to 6 carbon atoms, haloalkyl of 1 to 6 atoms, haloalkoxy of 1 to 6 carbon atoms, nitro, cyano, azido, mono or di-alkylamino the alkyls have 1 to 6 carbon atoms, pyrrolidinyl, morpholinyl, aralkoxy the alkoxy has 1 to 6 carbon atoms, or aryl, which two substituents can, if appropriate, be connected together and form a ring, or salt of a compound of formula (I).