Patent ID: 7951548
Filing Date: 2011-05-31
Classification: A61K,A61P,C12Q,G01N

Abstract:
1. A method for screening an IL-13 production inhibitor, which comprises (A) contacting a receptor protein represented by the amino acid of SEQ ID NO: 1 and having a ligand binding activity, or a salt thereof; with a ligand compound which is lysophosphatidyl-L-serine, or a salt thereof; (B) contacting the receptor protein or a salt thereof with the ligand compound and a test compound; (C) measuring the binding amounts of the ligand compound to the receptor protein in (A) and (B); and (D) comparing the binding amounts in (A) and (B), wherein greater binding in (A) compared to (B) is indicative of an IL-13 production inhibitor, thereby screening an IL-13 production inhibitor.