Patent ID: 8445517
Filing Date: 2013-05-21
Classification: A61K,A61P,C12Q,G01N

Abstract:
1. A method for inhibiting Stat3 activity in a cell, comprising contacting said cell with an effective dose of a compound selected from the group consisting of pyrimethamine, pimozide, guanabenz acetate, alprenolol hydrochloride, nifuroxazide, solanine alpha, fluoxetine hydrochloride, ifosfamide, pyrvinium pamoate, moricizine hydrochloride, 3-(1,3-benzodioxol-5-yl)-1,6-dimethyl-pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)- dione and 3-(2-hydroxyphenyl)-3-phenyl-N,N-dipropylpropanamide or a salt or ester thereof and detecting Stat3 activity in said cell.