Patent ID: 9095602
Filing Date: 2015-08-04
Classification: A61K,A61P,C07K

Abstract:
1. A method for treating an individual suffering from ovarian cancer comprising administering to said individual a therapeutically effective amount of an antisence oligonucleotide and chemotherapy comprising a taxane, wherein the antisence oligonucleotide has nucleotides in the sequence set forth in Seq. ID No. 4 and which antisense oliglnucleotide comprises a phosphorothioate modification to increase the stability thereof in vivo, and wherein the antisense oligonucleotide is administered to said individual before and after the chemotherapy such that the expression of testosterone-repressed prostate message-2 (TRPM-2) is reduced during at least a portion of the time that the taxane is active, thereby treating said individual.