Patent ID: 8796184
Filing Date: 2014-08-05
Classification: G01N

Abstract:
1. A biomolecular detector, comprising: (a) a substrate having a surface portion; (b) a linking layer on said surface portion; (c) a polymer layer formed on said linking layer, said polymer comprising monomeric units, with each of said monomeric units comprising a monomer core group having at least one protein-resistant head group coupled thereto, to thereby form a brush molecule on said surface portion; said brush molecule comprising a stem formed from the polymerization of said monomer core groups, and a plurality of branches formed from said head group projecting from said stem; and (d) a first member of a specific binding pair directly non-covalently bound to said polymer layer; wherein said first member is bonded to said polymer layer at a density of from 1 milligram per meter