Patent ID: 6291447
Filing Date: 2001-09-18
Classification: C07D,C07H

Abstract:
A compound having the structure: ##STR47##wherein:in combination F and F' is Ar.sub.1 as defined below;Ar.sub.1 is a monocyclic, bicyclic or tricyclic, fully or partially aromatic system containing five or six membered carbocyclic or, oxygen, nitrogen or sulphur containing heterocyclic rings, optionally substituted with R or Z;W is selected from the group consisting of formula (i) and (ii), wherein the structures are as follows: ##STR48##in which K, E and T are independently selected from the group consisting of: N, CR and CZ, and wherein R and Z are as defined below; and ##STR49##in which K and E are independently selected from the group consisting of: N, CR and CZ, and wherein R, Z and Q are as defined below;R.sub.1, is selected from the group consisting of: R; RCO--; Ar.sub.2 CO--; and, Ar.sub.2 CH.sub.2 --, wherein Ar.sub.2 is an aromatic substituent selected from the group consisting of: phenyl, naphthyl, anthracyl, phenanthryl, furan, pyrrole, thiophene, benzofuran, benzothiophene, quinoline, isoquinoline, imidazole, thiazole, oxazole, and pyridine, and Ar.sub.2 may be optionally substituted with R or Z, wherein R and Z are as defined below;R is selected from the group consisting of H; and a structural fragment having a saturated or unsaturated linear, branched, or cyclic, skeleton containing one to ten carbon atoms in which the carbon atoms may be optionally substituted with a substituent selected from the group consisting of: --OH; --OR.sub.3 ; --O.sub.2 CR.sub.3, --SH; --SR.sub.3 ; --SOCR.sub.3 ; --NH.sub.2 ; --NHR.sub.3 ; --NH(R.sub.3).sub.2 ; --NHCOR.sub.3 ; NRCOR.sub.3 ; --I; --Br, --Cl; --F; --CN; --CO.sub.2 H; --CO.sub.2 R.sub.3 ; --CHO; --COR.sub.3 ; --CONH.sub.2 ; --CONHR.sub.3 ; --CON(R.sub.3).sub.2 ; --COSH; --COSR.sub.3 ; --NO.sub.2 ; --SO.sub.3 H; --SOR.sub.3 ; and --SO.sub.2 R.sub.3, wherein R.sub.3 is a linear, branched or cyclic, one to ten carbon saturated or unsaturated alkyl group;Z is an optional substituent selected from the group consisting of: H; --OH; --OR; --O.sub.2 CR; --SH; --SR; --SOCR; --NH.sub.2 ; --NHR; --NH(R).sub.2 ; --NHCOR; NRCOR; --I; --Br; --Cl; --F; --CN; --CO.sub.2 H; --CO.sub.2 R; --CHO; --COR; --CONH.sub.2 ; --CONHR; --CON(R).sub.2 ; --COSH; --COSR; --NO.sub.2 ; --SO.sub.3 H; --SOR; and, --SO.sub.2 R;Q is selected from the group consisting of: NR.sub.1 ; O; S, and C(R).sub.2 ; andX and Y are independently selected from the group consisting of: O; H, OH; and H.sub.2.