Patent ID: 6380185
Filing Date: 2002-04-30
Classification: C07D

Abstract:
A compound of the formula: whereinR1, R2 and R3 are independently selected from hydrogen, C1-C6 alkyl, C1-C6 alkoxy, â€”CF3, â€”NO2, cyano, C1-C6 alkyl (straight chain or branched), trifluoromethyl, â€”OH or the C1-C12 esters (straight chain or branched) or C1-C12 alkyl ethers (straight chain or branched or cyclic) thereof, halogen, or C1-C6 halogenated ethers; R4 and R5 are independently selected from H or benzyl, the benzyl group being optionally substituted by C1-C6 alkyl, C1-C6 alkoxy, â€”CF3, or halogen; X is H, C1-C6 alkyl, or CF3; Z is O or S; n is 2 or 3; Y is selected from: a) a moiety of the formula: â€ƒwherein Râ€² is C1-C6 lower alkyl; or b) a moiety selected from the group of: or a pharmaceutically acceptable salt thereof.