Patent ID: 7741457
Filing Date: 2010-06-22
Classification: A61P,C07H,Y02P

Abstract:
1. An oligomeric compound having at least one monomer of formula: or of formula: or of formula: wherein independently for each of said at least one monomer of formula I, II or III: Bx is a heterocyclic base moiety; T Z is C each substituted group is, independently, mono or poly substituted with optionally protected substituent groups independently selected from halogen, oxo, hydroxyl, OJ wherein said oligomeric compound further comprises at least one monomeric subunit selected from a β-D-2′-deoxyribonucleoside, a β-D-ribonucleoside and a nucleoside having a modified sugar moiety wherein each of said modified sugar moieties is, independently, selected from a modified sugar moiety that is substituted with a substituent group, substituted at the 4′-O with a 4′-S, 4′-amino or C wherein said oligomeric compound comprises from 8 to 40 nucleosides and/or modified nucleosides or mimetics in length.