Patent ID: 8129179
Filing Date: 2012-03-06
Classification: B01L,C12M,Y10S

Abstract:
1. A bioreactor comprising: (a) a substrate having a first surface and an opposite second surface, defining a channel therein; (b) a plurality of chambers formed in the substrate, wherein each of the plurality of chambers is adapted for receiving and culturing at least one predetermined type of cells in a liquid medium and formed with an open end, an opposite closed end and side walls, the open end and the closed end defining a depth, d, therebetween for the corresponding chamber, the sidewalls defining a width, w, therebetween for the corresponding chamber, and the chamber being in fluid communication with the channel through the open end; (c) means adapted for electrochemical measurements of the cells responsive to the liquid medium in at least one of the chambers; and (d) a barrier for at least one of the chambers, wherein the barrier: