Patent ID: 8623311
Filing Date: 2014-01-07
Classification: A61K,A61L,C01B,C04B

Abstract:
1. A process in solution for the manufacture of a gallium-doped phosphocalcic compound of formula (I): Ca (10.5-1.5x) Ga x (PO 4 ) 7 having a structure close to β-tricalcium phosphate (β-TCP), wherein 0<x<1 and the salts, hydrates and mixtures thereof, comprising the following steps: (a) preparing an aqueous solution containing a calcium compounds and an appropriate quantity of a gallium compound; (b) adjusting the pH of the solution obtained in step (a) to a value of 8.5 to 12; (c) adding to said solution an appropriate quantity of a phosphate compound; (d) precipitating the gallium doped phosphocalcic compound by adjusting the pH of the obtained solution to a value of 7.0 to 12; (e) separating the precipitated gallium doped phosphocalcic compound from the solution; and (f) calcining the gallium doped phosphocalcic compound obtained.