Patent ID: 7163942
Filing Date: 2007-01-16
Classification: A61P,C07C,C07D

Abstract:
1. A compound of the Formula I wherein R 1 and R 2 are each independently selected from —H, —C 1 –C 8 alkyl, —C 2 –C 8 alkenyl, —C 1 –C 8 alkoxy, —C 2 –C 8 alkenoxy, —C 1 –C 8 hydroxyalkyl, —C 2 –C 8 hydroxyalkenyl, -halo, —CN, —NO 2 , —(CH 2 ) q NC(═O)R 6 , —(CH 2 ) q C(═O)OR 5 , —(CH 2 ) q C(═O)NR 6 R 7 , —(CH 2 )qNR 6 R 7 , C 3 –C 8 cycloalkyl and —C 5 –C 8 cycloalkenyl, wherein R 1 and R 2 are each optionally independently substituted with from one to three substituents independently selected from —C 1 –C 6 alkoxy, —C 1 –C 6 alkyl -halo and —OH; R wherein B is absent or is selected from C 1 –C 8 alkylene and C 2 –C 4 alkenylene; D is selected from —C X, Y and Z are each independently selected from —H, —C wherein said X, Y and Z are each optionally independently substituted with from one to three substituents independently selected from —C and wherein said alkoxy substituent of X, Y and Z is optionally independently substituted with from one to three substituents independently selected from halo; R wherein NR m is 0, 1, 2 or 3; n is 0, 1, 2 or 3; and q is 0, 1 or 2; or a pharmaceutically acceptable salt thereof.