Patent ID: 6602991
Filing Date: 2003-08-05
Classification: A61K,A61P,C07H,Y02A

Abstract:
Process for preparing a charcoal-GM1 complex, characterized by comprising the stages of:(A) preparing a diluente solution (A) composed of 0 to 0.900% of sodium chloride, from 0 to 0.030% of monobasic sodium phosphate-2H2O, and 0 to 0.400% of dibasic sodium phosphate-12H2O, dissolved in distilled water; (b) dissolving, in part of the solution (A) from 0.200 to 4.000% of GM1, then obtaining a new solution (B); (c) suspending activated charcoal in the other part of the solution (A) in the proportion of 1:3 to 1:7 w/v, starting and maintaining moderated agitation for a period of 5 to 15 minutes; (d) slowly adding under agitation, adequate quantities of the solution (B) in such way as to obtain proportions varying from 1:100 and 1:10 (GM1:charcoal), and the agitation is maintained by a period of 10 to 20 minutes; (e) filtering the suspension, washing the complex with the solution (A) and submitting it to drying; and, (f) passing the dry complex through a 40 â€œmeshâ€  sieve and storing the product in a hermetically sealed recipient.