Patent ID: 7947307
Filing Date: 2011-05-24
Classification: A61K,B82Y,Y10S

Abstract:
1. A synthetic nanoparticle, said synthetic nanoparticle comprising: at least one apolipoprotein that is not an apoB lipoprotein, at least one amphipathic lipid, and at least one metallic or non-metallic contrast agent conjugated to a component of said nanoparticle, said at least one metallic or non-metallic contrast agent being present in an amount between 5% to about 50% (w/w) of said nanoparticle, and said synthetic nanoparticle having a diameter from about 5 nm to about 50 nm, and wherein said nanoparticle further comprises a C—C chemokine receptor type 7 (CCR7) targeting moiety for monitoring atherosclerosis.