Patent ID: 7629167
Filing Date: 2009-12-08
Classification: B01F,C12M

Abstract:
1. A bioreactor system comprising: a disposable container for housing biomaterials for processing, the disposable container comprising a single chamber including at least one input port; a fitting comprising a porous surface associated with the input port and configured for allowing the passage of an inlet gas stream and controlling gas bubble size and distribution prior to addition of the inlet gas stream to the interior of the single chamber, wherein the pore size of the porous surface is chosen from macro, micron, submicron, nano, and combinations thereof; a disposable mixing system comprising an impeller positioned above the porous surface and within the single chamber at a lower portion of the single chamber, the impeller configured to be driven by a motor magnetically coupled to the impeller and external to the lower portion of the single chamber such that biomaterials contained within the single chamber are mixed and gas bubble circulation is increased; at least one exhaust port; at least one harvest port; a structure for supporting the disposable container; one or more sensors for sensing one or more parameters of the biomaterials in the container; and a heater for heating the contents of the disposable container, the heater having a thermostat.