Patent ID: 8551136
Filing Date: 2013-10-08
Classification: A61L,C08J

Abstract:
1. A kit for preparing a high swell, long-lived sealant comprising: a) a first aqueous solution or dispersion comprising at least one highly oxidized polysaccharide containing aldehyde groups, said highly oxidized polysaccharide having a weight-average molecular weight of about 1,000 to about 1,000,000 Daltons and an equivalent weight per aldehyde group of about 65 to about 85 Daltons, wherein said first aqueous solution or dispersion contains said highly oxidized polysaccharide at a concentration of greater than or equal to about 3% but less than 6% by weight; and b) a second aqueous solution or dispersion comprising at least one water-dispersible, multi-arm amine wherein at least three of the arms are terminated by at least one primary amine group, said multi-arm amine having a number-average molecular weight of about 450 to about 200,000 Daltons, wherein said second aqueous solution or dispersion contains said multi-arm amine at a concentration of about 5% to about 70% by weight; wherein the high swell, long-lived sealant is formed when (i) the concentration of the highly oxidized polysaccharide in the first aqueous solution or dispersion is equal to or greater than 5 wt % but less than 6 wt %, the equivalent weight per aldehyde group of the highly oxidized polysaccharide is about 80 to about 85 Daltons; or (ii) the concentration of the highly oxidized polysaccharide in the first aqueous solution or dispersion is equal to or greater than 3 wt % but less than 5 wt %, the equivalent weight per aldehyde group of the highly oxidized polysaccharide is about 65 to about 85 Daltons.