Patent ID: 8515524
Filing Date: 2013-08-20
Classification: A61B,A61N

Abstract:
1. A method of stimulating angiogenesis of a tissue in the vicinity of an implantable medical device by use of an ultrasonic medical apparatus including an ultrasonic irradiation means including a transducer, the method comprising the steps of: implanting, into a body, the implantable medical device whose surface has been covered with a titanium oxide material; and extracorporeally irradiating, by use of the ultrasonic irradiation means including the transducer, with ultrasonic waves, the titanium oxide material provided on the surface of the implantable medical device thus implanted, the titanium oxide material being a titanium oxide composite material produced by covering a surface of a polymer base material with titanium oxide, the titanium oxide composite material being composed of (a) a polymer base material having an active group and (b) titanium oxide having a reactive functional group capable of reacting with the active group, and the titanium oxide composite material being produced through chemical bonding between the active group and the reactive functional group.