Patent ID: 6174873
Filing Date: 2001-01-16
Classification: A61K,A61P,Y10S

Abstract:
A method for treating a patient having a disease, comprising:orally administering to the patient a pharmacoutically-effective amount of a composition which is adapted for oral administration and comprisesan acid-labile 2'-deoxyadenosine analog which chemically decomposes In an acidic environment of the stomach, andone or more components of the composition which inhibit the 2'-deoxy adenosine analog from decomposing in the acidic environment of the stomach by isolating the adenosine analog from the acidic environment of the stomach,whereinthe disease is selected from the group consisting of hematological malignanies and solid tumors; andthe one or more components of the composition are selected from the group consisting of erodible matrix, enteric coating, solid dispersion, and ion exchange resin.