Patent ID: 6177464
Filing Date: 2001-01-23
Classification: A61P,C07C,C07D

Abstract:
A compound represented by the formula (Formula I): ##STR26##in whichX is CR'.sub.1 R'.sub.2 ;Y is CR.sub.1 R.sub.2 ;R.sub.1 and R.sub.2 are each independently for each occurrence hydrogen, halogen, or substituted or unsubstituted alkyl, alkenyl, alkynyl, aryl, heterocyclyl, amino, acylamino, hydroxy, alkoxy, aryloxy, carboxy, alkylcarbonyl, arylcarbonyl, alkoxycarbonyl, aryloxycarbonyl, aminocarbonyl, alkylcarbonyloxy, arylcarbonyloxy, aminocarbonyloxy, or alkylthio; or R.sub.1 and R.sub.2 taken together are O or S;R'.sub.1 and R'.sub.2 are each independently for each occurrence hydrogen, halogen, or substituted or unsubstituted alkyl, alkenyl, alkynyl, aryl, heterocyclyl, amino, acylamino, hydroxy, alkoxy, aryloxy, carboxy, alkylcarbonyl, arylcarbonyl, alkoxycarbonyl, aryloxycarbonyl, aminocarbonyl, alkylcarbonyloxy, arylcarbonyloxy, aminocarbonyloxy, or alkylthio; or R'.sub.1 and R'.sub.2 taken together are O or S;R.sub.3 and R.sub.4 are each independently hydrogen, halogen, cyano, nitro, boronato, stannyl, silyl, or substituted or unsubstituted alkyl, alkenyl, alkynyl, aryl, cycloalkyl, heterocyclyl, carboxy, alkylcarbonyl, arylcarbonyl, alkoxycarbonyl, aryloxycarbonyl, aminocarbonyl, alkylcarbonyloxy, arylcarbonyloxy, or aminocarbonyloxy, provided that either R.sub.3 or R.sub.4 is hydrogen;or a first occurrence of R.sub.1 or R.sub.2, taken together with a second occurrence of R.sub.1 or R.sub.2, and the carbon atoms to which they are attached, form a carbocyclic or heterocyclic ring;or at least one of R.sub.1, R.sub.2, R'.sub.1, R'.sub.2, or R.sub.5, is a linker group to a solid support;or a salt thereof.