Patent ID: 6313125
Filing Date: 2001-11-06
Classification: A61P,C07D

Abstract:
A compound represented by Formula I': ##STR10##wherein:R.sup.1' is hydrogen or fluorine;X' is pyridyl, pyrazinyl, pyridazinyl or pyrimidinyl which is unsubstituted or substituted by methyl, CF.sub.3, methoxy, bromine, chlorine, isopropoxy, dimethylamino or X' is substituted by a 5-membered heterocyclic ring having 1, 2 or 3 nitrogen heteroatoms, and X' is optionally fused to a benzene ring, or X' is pyrazolyl, isothiazolyl, isoxazolyl, 1,2,4-triazolyl, thiazolyl, 1,2,3-triazolyl or imidazolyl which is unsubstituted or substituted by one, two or three groups independently chosen from methyl, CF.sub.3 and chlorine or is substituted by a phenyl, benzyl or pyridyl ring which ring is unsubstituted or substituted by chlorine or CF.sub.3, or X' is phenyl which is unsubstituted or substituted by chlorine;Y' is CH.sub.2 ; andZ' is furanyl;or a pharmaceutically acceptable salt thereof.