Patent ID: 7731685
Filing Date: 2010-06-08
Classification: A61F,A61L,A61M,A61P

Abstract:
1. An implantable medical device for delivering a bioactive material to a vessel wall of a patient comprising: a balloon catheter having an expandable balloon attached to a catheter shaft, the balloon having an expandable outer surface formed from a base material; a hydrophilic layer including a hydrophilic material posited on the outer surface; and a bioactive layer including a total of about 5 micrograms to about 500 micrograms of a lipophilic bioactive material disposed on the hydrophilic layer over the outer surface and about 0.2 micrograms to about 20 micrograms of the lipophilic bioactive material per square mm of the expanded outer surface of the balloon; the expandable balloon being free of any additional coating or layer atop the bioactive layer and the hydrophilic layer being positioned between the expandable outer surface and the bioactive material, wherein the hydrophilic layer is chosen such that the adhesion of the bioactive material to the hydrophilic layer is less than the adhesion of the bioactive material to the base material and wherein the hydrophilic layer enhances delivery of the bioactive material to the vessel wall.