Patent ID: 8481058
Filing Date: 2013-07-09
Classification: A61K,A61P,A61Q,Y10S

Abstract:
1. A topical composition precursor comprising a result of melt processing at a temperature of at least 50° C.: (a) a hydrophobic polymer composition comprising poly(vinylpyrrolidone/alkylene) polymer, wherein the alkylene group contains at least 10 carbon atoms; (b) a hydrophilic polymer composition comprising poly(maleic acid/methylvinylether) copolymer having an average molecular weight of at least 50,000; and (c) the topical composition precursor contains less than 1 wt. % water; wherein a complex is provided between the poly(vinylpyrrolidone/alkylene) polymer and the poly(maleic acid/methylvinylether) copolymer as a result of the melt processing, and wherein the poly(vinylpyrrolidone/alkylene) polymer is provided at a concentration of about 72 wt. % to about 98 wt. % and the poly(maleic acid/methylvinylether) copolymer is provided at a concentration of about 2 wt. % to about 25 wt. %, based on the weight of the topical composition precursor.