Patent ID: 8029730
Filing Date: 2011-10-04
Classification: G01N

Abstract:
1. A flow cell for use with flow-based chemiluminescence measurements, the flow cell comprising: (a) a flat thin plate having first and second faces, and having a groove in the first face of the plate, the groove having first and second ends; (b) a flat window having first and second faces, the plate and the window forming a flow channel in the groove in the first face of the plate when the first face of the plate is pressed against the first face of the window, the flow channel having first and second end walls, the first wall being the first face of the plate, the second wall being the first face of the window; (c) an inlet for the groove at the first end of the groove in the first face of the plate, the inlet port penetrating through the plate, the groove having a plurality of loops formed between the first and second ends, each loop comprising a pair of oppositely-directed horseshoe-shaped curves connected to one another by a segment lateral to the pair of oppositely-directed horseshoe-shaped curves, to enhance mixing of a sample and a reagent, and thereby increase generating and emission of chemiluminescence; (d) an outlet for the groove at the second end of the groove in the first face of the plate, the outlet penetrating through the plate; and (e) a light detector disposed in a path of the chemiluminescence generated in and emitted from the groove of the flow cell.