Patent ID: 6506888
Filing Date: 2003-01-14
Classification: C07H,C07K,C12N,C12Q

Abstract:
A polynucleotide comprising, at one or more positions, a nucleoside or a nucleotide comprising a sugar portion, wherein the 2â€² position of said one or more sugars independently has the formula: 2â€²-Oâ€”NHR1, wherein R1 is selected from a group consisting of H, aminoacyl group, peptidyl group, biotinyl group, cholesteryl group, lipoic acid residue, retinoic acid residue, folic acid residue, ascorbic acid residue, nicotinic acid residue, 6-aminopenicillanic acid residue, 7-aminocephalosporanic acid residue, alkyl, alkenyl, alkynyl, aryl, alkylaryl, carbocyclic aryl, heterocyclic aryl, amide and ester.