Patent ID: 6451296
Filing Date: 2002-09-17
Classification: A61K,A61Q

Abstract:
A method of preparing a stable polyhydric alcohol solution of an aluminum-zirconium antiperspirant solution having enhanced efficacy by having a high proportion of lower molecular weight aluminum complex species comprisingheating an aqueous solution of an aluminum salt with a zirconium compound having the formula ZrO(OH)2âˆ’ab(X)b wherein b can vary from 0.5 to 2; a is the valence of X; (2âˆ’ab) is greater than or equal to zero; and X is a member selected from the group consisting of halide, nitrate, perchlorate, carbonate or sulfate ion in the presence of from 20 to 70 percent by weight of a polyhydroxy alcohol having at least two carbon atoms to which at least two hydroxy groups are attached, and mixtures thereof, and aluminum metal at a temperature of about 100-140Â° C. to obtain an aluminum-zirconium complex in the polyhydric alcohol to a concentration of about 20 to 45% by weight on an anhydrous basis.