Patent ID: 7833798
Filing Date: 2010-11-16
Classification: G01N

Abstract:
1. A method of analyzing albumin in a sample solution taken from a test subject, the method comprising the following steps: A) forming the sample solution by diluting a sample comprising albumin 50- to 100000-fold with a buffer, B) adjusting the pH of the sample solution to pH 4-9 with a buffer, C) incubating the sample solution of step B) at an incubation temperature of between 4-60° C. for at least 2 hours, D) after step C), subjecting the sample solution to either mass spectrometry, liquid chromatography, or both, and E) determining the amount of reduced albumin and oxidized albumin, and/or the ratio of reduced albumin to oxidized albumin in the sample solution; wherein said sample solution is selected from the group consisting of blood and plasma.