Patent ID: 6881545
Filing Date: 2005-04-19
Classification: C07K

Abstract:
1. A screening method for a compound capable of changing the binding activity of a ligand polypeptide comprising the amino acid sequence of SEQ ID NO: 73, or its amide or ester, or a salt thereof, or a partial peptide of said ligand polypeptide, or its amide or ester, or a salt thereof, with a receptor protein comprising the amino acid sequence of SEQ ID NO:21; SEQ ID NO:22, or a salt thereof, or a partial peptide of said receptor protein, or a salt thereof, the method comprising making a comparison of said binding activity between: (i) at least one case where said ligand polypeptide, or its amide or ester, or a salt thereof, or a partial peptide of said ligand polypeptide, or its amide or ester, or a salt thereof is contacted with said receptor protein or a salt thereof or a partial peptide of said receptor protein, or a salt thereof, and (ii) at least one case where said ligand polypeptide or its amide or ester, or a salt thereof, or a partial peptide of said ligand polypeptide, or its amide or ester, or a salt thereof together with a sample containing the compound to be tested is contacted with the receptor protein or a salt thereof or a partial peptide of said receptor protein or a salt thereof.