Patent ID: 6919336
Filing Date: 2005-07-19
Classification: A61P,C07C,C07D

Abstract:
1. A compound of formula I wherein X is N or CH; R1 is H, halogen, or optionally substituted (lower alkoxy, lower alkyl or halo-substituted lower alkyl); R2 is H, or optionally substituted (heterocyclyl, lower alkyl lower alkene, lower alkyne or lower alkoxy); R3 is H, or optionally substituted (heterocyclyl, lower alkyl lower alkene, lower alkyne or lower alkoxy); or R2 and R3 are linked together to form an optionally substituted 4- to 6-membered heterocyclic ring containing one or more hetero atoms selected from O, S, N, NR, where R is H or lower alkyl, and R4 represents two or three independent halogen substituents, or a pharmaceutically-acceptable and -cleavable ester or acid addition salt thereof.