Patent ID: 6663833
Filing Date: 2003-12-16
Classification: G01N,Y10T

Abstract:
An assay device for detecting an analyte in a sample, consisting of:a continuous liquid flow channel having a proximal end and a distal end, wherein liquid flow between the proximal end and distal end is independent of gravity, wherein the continuous liquid flow channel includes an internal cross-sectional shape comprising an acute angle for: promoting capillary flow within the liquid flow channel, regulating the flow rate through the liquid flow channel to permit a reaction in the liquid flow channel; a detection membrane, wherein the distal end of the liquid flow channel is in liquid flow communication with the detection membrane, wherein the detection membrane captures a product of the reaction from the liquid flow channel; and a sample delivery means comprising a sample well in which the sample is collected; and a capillary channel, wherein the sample well is in liquid flow communication with the capillary channel for delivering a predetermined volume of sample from the sample well to the liquid flow channel when the sample delivery means is manipulated to place the capillary channel in liquid flow communication with the liquid flow channel, wherein liquid flow of the sample is induced by a resultant capillary flow, and a reaction within the liquid flow channel is initiated by the resultant capillary flow from the sample delivery means; and an end of test indicator for indicating that the liquid has traveled to the distal end of the continuous liquid flow channel and the resulting reaction and detection membrane are ready for analysis.