Patent ID: 8088925
Filing Date: 2012-01-03
Classification: A61P,C07D

Abstract:
1. A compound of formula Ia: wherein: R1 is bromine, methyl or chlorine, R2 is hydrogen atom, R3 is a hydrogen atom, —(C R6 is heterocyclyl, wherein heterocyclyl is selected from benzisoxazolyl, isoxazolyl, morholinyl, pyridyl, thiazolyl, thiadiazolyl and thienyl, and wherein heterocyclyl is independently of one another unsubstituted or mono-, di- or trisubstituted by R7, R7 is chlorine or ═O, R8 is —(C R10 is hydrogen atom, —(C R21 and R22 are independently of one another identical or different and are hydrogen atom or —(C R21 and R22 together with the nitrogen atom to which they are bonded can form a heterocyclic ring from the group N-methyl-piperazine and morpholine, G R13 is a hydrogen atom, —(C R13 and R3 together with the atoms to which they are bonded form a isothiazolidine 1,1-dioxide, [1,2]thiazinane 1,1-dioxide or [1,4,3]oxathiazinane 4,4-dioxide group and wherein said group is unsubstituted or substituted one time by ═O, G