Patent ID: 8182834
Filing Date: 2012-05-22
Classification: A61K

Abstract:
1. A particulate composition, said composition comprising; a) at least 50% of at least one structure forming amphiphile comprising at least one lipid component selected from phospholipids, glycolipids, and diglycerides, b) 2 to 40% of at least one structure swelling amphiphile comprising at least one swelling agent selected from polyoxyethylene alkylethers, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene fatty acid esters, polyoxyethylene castor oil derivatives or polyoxyethylene lipid derivatives, and c) 2 to 20% of at least one dispersion stabilising polymeric amphiphile comprising at least one polymeric agent selected from poloxamers, PEG-glyceroldioleate, PEG fatty acid esters or PEG-phospholipids, wherein all parts are by weight relative to the sum of the weights of a+b+c and wherein the composition comprises non-lamellar particles or forms non-lamellar particles when contacted with an aqueous fluid.