Patent ID: 8271206
Filing Date: 2012-09-18
Classification: G16B

Abstract:
1. A method for automated assembly of DNA sequence data comprising of DNA fragment reads into contiguous DNA segments using a computer system with processing and information storage capabilities, the method comprising the steps of: entering into the computer system a plurality of DNA fragment reads; identifying a plurality of n-mers within each DNA fragment read of a plurality of the DNA fragment reads and compiling an index of the of n-mers; identifying one or more anchor sequences common to a plurality of the reads among the indexed n-mers; and generating a consolidated sequence using a plurality of reads comprising the same indexed anchor sequence, wherein the consolidated sequence is generated by sub-grouping the plurality of reads comprising the same indexed anchor sequence according to two or more different shoulder sequences thereby producing two or more subgroups of reads and generating one or more consolidated sequences, wherein each of the one or more consolidated sequences is generated using reads of one of the two or more subgroups.