Patent ID: 6867310
Filing Date: 2005-03-15
Classification: C07C,C07D,C07F

Abstract:
1. A method represented by Scheme 1: wherein G represents, independently for each occurrence, an electron withdrawing group selected from the group consisting of formyl, acyl, —C(O)OR, —C(O)NR R represents, independently for each occurrence, hydrogen, alkyl, aryl, heteroalkyl, heteroaryl, halogen, alkylamino, arylamino, alkylthio, arylthio, alkoxy, aryloxy, or —(CH Ar represents an aromatic or heteroaromatic moiety, X represents halogen, —OTf, —ONf, —OTs, —OMs, (alkyl)S(O) the transition metal catalyst consists essentially of palladium and one to four inclusive monodentate ligands selected from the group consisting of OAc, Cl, CH base represents a Bronsted base; R m, independently for each occurrence, is an integer selected from the range 0 to 8 inclusive; q is an integer selected from the range 1 to 3 inclusive; and p is an integer equal to (3-q).