Patent ID: 7446229
Filing Date: 2008-11-04
Classification: C07C,C07D

Abstract:
1. A compound of formula Ia below, including physiologically acceptable salts, diastereomers, enantiomers, double bond isomers, or mixtures thereof; wherein: Y is selected from >C═O, >CH—(CH R R wherein each Z is independently selected from S, O, NH, N(CH W is selected from O, S or CR D is selected from a cycloalkyl ring, a heterocyclic ring, an adamantyl ring, an heteroadamantyl ring or any above ring optionally substituted by R L is selected from a cycloalkyl ring, a heterocyclic ring, an aromatic ring, a heteroaromatic ring, an adamantyl ring, an heteroadamantyl ring or any above ring optionally substituted by R R R R Q is selected from O, S, NH or N(R R with the following provisos: if Y is C═O, and R (where n is an integer between 1-3), and R 2 is selected from H, OH or OCH 3 , then R 3 cannot be selected from (CH 2 ) n C≡CH where n is an integer from 3-5 or where each X is independently selected from CH 2 , O, S and NH and n is an integer from 3-5; if Y is C═O, and R (where n is an integer between 1-3), and R 2 is selected from H, OH or OCH 3 , then R 3 cannot be selected from structure Ia 3 where D is an adamantyl ring and R 4 is selected from H, (CH 2 ) n CH 3 (where n is an integer from 4-6) or C(CH 3 ) 2 (CH 2 ) n CH 3 (where n is an integer from 3-5); if Y is C═O, and R if Y is C═O, and R if Y is C═O, and R