Patent ID: 6680177
Filing Date: 2004-01-20
Classification: C12Q,G01N,Y10S

Abstract:
A method for measuring low molecular weight heparin concentration on a whole blood sample, comprising:(i) combining a first, whole blood, component of the assay with a second component of the assay to form a resulting mixture, wherein said second component comprises a dry coagulation assay reagent arranged in a substantially flattened configuration and containing magnetic particles distributed substantially homogeneously therethrough and comprising a factor Xa activator, and wherein said resulting mixture is subjected to (ia) an oscillating magnetic field or (ib) a moving permanent magnetic field or (ic) a combination of an oscillating magnetic field and a stationary permanent magnetic field or (id) a rotating magnetic field, whereby said combining of said first component with said second component substantially simultaneously initiates movement of said magnetic particles and a coagulation assay measurement; and (ii) monitoring movement induced in said magnetic particles by (ia) or (ib) or (ic) or (id) to obtain said coagulation assay measurement, wherein said coagulation assay measurement correlates to a concentration of low molecular weight heparin in the whole blood sample.