Patent ID: 8178077
Filing Date: 2012-05-15
Classification: A61K,A61P,C07C,C07H,C07J,C07K,G01N

Abstract:
1. A method for screening a drug, which comprises evaluating whether or not a test substance regulates the expression or function of an NCS protein gene by performing the following steps (a) to (c): (a) a step for bringing the test substance into contact with the NCS protein or mutant protein thereof; (b) a step for measuring the functional level of the NCS protein or mutant protein thereof in the presence of the test substance, and comparing said functional level with the functional level of the NCS protein or mutant protein thereof in the absence of the test substance; (c) a step for selecting a test substance that alters the functional level of the NCS protein or mutant protein thereof on the basis of the result of the comparison in (b) above.