Patent ID: 9028463
Filing Date: 2015-05-12
Classification: A61B,A61K,A61M,A61P,C12N

Abstract:
1. A method for enhancing the efficacy of an influenza vaccine using a microneedle device for increasing IgG antibody titer and IgA antibody titer in a patient in need thereof comprising applying an adjuvant containing lauryl alcohol to an administration site after administering the influenza vaccine, wherein the microneedle device comprises a plurality of microneedles, and the microneedles are made of polylactic acid, capable of puncturing skin, arranged two-dimensionally on a base, and coated with a coating comprising an influenza virus antigen comprising a type A strain and a type B strain and pullulan as a coating carrier, wherein the method comprises the step of increasing IgG antibody titer and IgA antibody titer in a patient in need thereof.