Patent ID: 7429564
Filing Date: 2008-09-30
Classification: A61K,A61P

Abstract:
1. A method of treating a human patient with diabetes mellitus, comprising orally administering to a human diabetic patient an oral dosage form comprising a dose of unmodified insulin, and an effective amount of a delivery agent of the formula or a pharmaceutically acceptable salt thereof: wherein i. X is hydrogen or halogen; and ii. R is substituted or unsubstituted C1-C3 alkylene, substituted or unsubstituted C1-C3 alkenylene, substituted or unsubstituted C1-C3 alkyl (arylene), substituted or unsubstituted C1-C3 aryl (alkylene), wherein said dosage form achieves a therapeutically effective reduction in blood glucose after oral administration to a human diabetic patient as compared to an untreated diabetic patient.