Patent ID: 6841553
Filing Date: 2005-01-11
Classification: A61P,C07D

Abstract:
1. A bicyclic heteroaromatic compound of formula II, or a pharmaceutically acceptable salt thereof, wherein R R R B is N(H), O, or a bond and Y═CH or N, with the proviso that the compound is not ethyl 5-amino-2-ethoxycarbonylmethylthio-4-(pyridine-4-yl)-thieno[2,3-d]pyrimidine-6-carboxylate, 5-amino-6-(4-methylbenzoyl)-4-phenyl-2-[(4-methylphenyl)carbonylmethylthio]-thieno[2,3-d]pyrimidine, ethyl 5-amino-4-phenyl-2-ethoxycarbonylmethylthio-thieno[2,3-d]pyrimidine-6-carboxylate, methyl 5-amino-4-phenyl-2-methylthio-thieno[2,3-d]pyrimidine-6-carboxylate, ethyl 5-amino-4-phenyl-2-methylthio-thieno[2,3-d]pyrimidine-6-carboxylate, 6-acetyl-5-amino-4-phenyl-2-(2-oxopropylthio)-thieno[2,3-d]pyrimidine, 5-amino-6-benzoyl-4-phenyl-2-phenylcarbonylmethylthio-thieno[2,3-d]pyrimidine, 5-amino-6-(4-chlorobenzoyl)-4-phenyl-2-[(4-chlorophenyl)carbonylmethylthio]-thieno[2,3-d]pyrimidine, methyl 5-amino-4-(4-methoxyphenyl)-2-methylthio-thieno[2,3-d]pyrimidine-6-carboxylate, ethyl 5-amino-4-(4-methoxyphenyl)-2-methylthio-thieno[2,3-d]pyrimidine-6-carboxylate, methyl 5-amino-4-(4-chlorophenyl)-2-methylthio-thieno[2,3-d]pyrimidine-6-carboxylate, or ethyl 5-amino-4-(4-chlorophenyl)-2-methylthio-thieno[2,3-d]pyrimidine-6-carboxylate.