Patent ID: 8846054
Filing Date: 2014-09-30
Classification: A61K,A61P,C12N

Abstract:
1. A method of preventing abortion in a pregnant cow, comprising administering a vaccine to the pregnant cow, wherein the vaccine comprises a modified live Infectious Bovine Rhinotracheitis (IBR) virus that has been passaged at least 4 times in bovine embryo kidney cells, 22 times in ovine cells and once in MDBK cells, modified live Bovine Viral Diarrhea Virus (BVDV) Type 1 of a Singer strain that has been passaged at least twice in bovine turbinate cells, modified live BVDV Type 2 of Strain 296 that has been passaged in bovine testicular cells at least six times, or in embryonic swine kidney cells at least 23 times, or in MDBK cells at least 23 times, and Haemophilus somnus bacterin wherein the pregnant cow was vaccinated with a therapeutically effective amount of a vaccine comprising IBR, BVDV Type I and BVDV Type 2 prior to pregnancy.