Patent ID: 7524880
Filing Date: 2009-04-28
Classification: A61P,C07D

Abstract:
1. A crystalline naphthalene-1,5-disulfonic acid salt of 2-[(S)-1-(8-methylaminooctyl)pyrrolidin-3-yl]-2,2-diphenylacetamide characterized by at least one of (i) a powder x-ray diffraction pattern having two or more diffraction peaks at 2θ values selected from 5.45±0.2, 8.17±0.2, 12.02±0.2, 13.46±0.2, 14.00±0.2, 14.46±0.2, 15.69±0.2, 16.31±0.2, 17.22±0.2, 18.45±0.2, 20.13±0.2, 21.11±0.2, and 21.62±0.2; (ii) a differential scanning calorimetry trace which shows an onset of endothermic heat flow at about 200° C.; and (iii) an infrared absorption spectrum with significant absorption bands at about 696, 704, 765, 800, 1028, 1154, 1172, 1191, 1217, 1230, 1245, and 1669 cm −1 .