Patent ID: 6387951
Filing Date: 2002-05-14
Classification: C07C

Abstract:
A compound of the formula whereinA is phenyl or naphthyl said groups being optionally substituted with one or two R2 groups; X is O; Y is alkyl of 1 to 10 carbons, benzyl, lower alkyl or halogen substituted benzyl, fluoro-substituted alkyl of 1 to 10 carbons, cycloalkyl of 3 to 6 carbons, lower alkyl substituted cycloalkyl of 3 to 6 carbons, Cl, Br, or I; Z is â€”Câ‰¡Câ€”; R1 is independently H or alkyl of 1 to 6 carbons; R2 is independently H, alkyl of 1 to 6 carbons, F, Cl, Br, I, fluoro substituted alkyl of 1 to 6 carbons, alkoxy of 1 to 6 carbons, or alkylthio of 1 to 6 carbons; R3 is independently alkyl of 1 to 6 carbons, F, Cl, Br, I, fluoro substituted alkyl of 1 to 6 carbons, OH, SH, alkoxy of 1 to 6 carbons, alkylthio of 1 to 6 carbons or benzyl; m is an integer having the values 0 to 3; R7 is alkyl of 1 to 6 carbons, cycloalkyl of 3 to 6 carbons or lower alkyl substituted cycloalkyl of 1 to 6 carbons; n is an integer having the values of 1 to 4, and R8 is H, alkyl of 1 to 6 carbons, â€”CH2O(C1-6-alkyl), or a cation of a pharmaceutically acceptable base.