Patent ID: 6214795
Filing Date: 2001-04-10
Classification: A61K,A61P,C07K

Abstract:
A peptide compound comprising an amino acid sequence:Y.sub.1 -Xaa1-Xaa2-Xaa3-Xaa4-Xaa5-Xaa6-Xaa7-Xaa8-Xaa9-Y.sub.2 (SEQ ID NO: 1)wherein:Y.sub.1 is hydrogen, an amino-derivative group or a peptidic structure having a formula (Xaa).sub.a wherein Xaa is any amino acid structure and a is an integer from 1-15 inclusive;Y.sub.2 is hydrogen, a carboxy-derivative group or a peptidic structure having a formula (Xaa).sub.b wherein Xaa is any amino acid structure and b is an integer from 1-15 inclusive;Xaa1 is a tyrosine residue, a phenylalanine residue, a pyridylalanine residue, or a homophenylalanine residue;Xaa2 is a leucine residue, a norleucine residue, a phenylalanine residue, a pyridylalanine residue, a homophenylalanine residue, or an isoleucine residue;Xaa3 is an arginine residue, an aspartic acid residue, a glutamic acid residue, a serine residue, a tyrosine residue, or a glutamine residue;Xaa4 is a glutamine residue, a leucine residue, a norleucine residue, or a tyrosine residue;Xaa5 is a tyrosine residue;Xaa6 is a methionine residue, a leucine residue, a norleucine residue, a lysine residue, or an arginine residue;Xaa7 is a leucine residue, a norleucine residue, a methionine residue, an aspartic acid residue, a glutamic acid residue, an asparagine residue, or a serine residue;Xaa8 is an arginine residue, a leucine residue, a norleucine residue, a serine residue, or a threonine residue; andXaa9 is a leucine residue, a norleucine residue, a phenylalanine residue, a pyridylalanine residue, a homophenylalanine residue, a methionine residue, or a valine residue;or an inverso or retro-inverso isomer thereof.