Patent ID: 7550559
Filing Date: 2009-06-23
Classification: A61K,A61P,C07K

Abstract:
1. A compound, or enantiomers, stereoisomers, rotamers, tautomers, and racemates of said compound, said compound having the general structure shown in Formula I: or a pharmaceutically acceptable salt, solvate or ester thereof, wherein: R R A and M can be the same or different, each being independently selected from R, OR, N(H)R, N(RR′), SR, S(O R 2 and R 3 can be the same or different, each being independently selected from the group consisting of H, alkyl, heteroalkyl, alkenyl, heteroalkenyl, alkynyl, heteroalkynyl, cycloalkyl, spiro-linked cycloalkyl, heterocyclyl, aryl, arylalkyl, heteroaryl, and heteroarylalkyl; Y is selected from the following moieties: wherein G is NH; and R wherein each of said alkyl, aryl, heteroaryl, cycloalkyl, spiro-linked cycloalkyl, and heterocyclyl can be unsubstituted or optionally independently substituted with one or more moieties independently selected from the group consisting of hydroxy, alkoxy, aryloxy, thio, alkylthio, arylthio, amino, amido, alkylamino, arylamino, alkylsulfonyl, arylsulfonyl, sulfonamido, alkyl, alkenyl, aryl, heteroaryl, alkylsulfonamido, arylsulfonamido, keto, carboxy, carbalkoxy, carboxamido, alkoxycarbonylamino, alkoxycarbonyloxy, alkylureido, arylureido, halo, cyano, and nitro.