Patent ID: 8153381
Filing Date: 2012-04-10
Classification: C07K,G01N

Abstract:
1. A method, comprising a) contacting a sample comprising a pathogen with a first antibody specific for a variant-specific portion of the pathogen, wherein a pathogen-first antibody complex is formed if the variant-specific portion is present on the pathogen in the sample; b) removing the pathogen-first antibody complexes from said sample, if present; c) contacting the sample with a second antibody specific for a nonvariant-specific portion of the pathogen, wherein a pathogen-second antibody complex is formed if the pathogen is still present in the sample; and d) detecting the presence or absence of the second pathogen-antibody complexes; wherein the absence of said second pathogen-antibody complex indicates that the pathogen is of the variant for which the first antibody is specific.