Patent ID: 7241787
Filing Date: 2007-07-10
Classification: A61K

Abstract:
1. A compound of the formula I, in which the meanings are R1 H, (C R3, R4, R5, R6, R7, R8, R9, independently of one another H, (C K a group of the formula —(CR10R11) Z O, CO, N(R59), S, SO, SO R10, R11 independently of one another H, (C z 1, 2, 3, 4, 5, 6; R59H, (C E 3–14 membered bivalent carbo- or heterocyclic ring structure having 0–4 heteroatoms from the group of N, O and S, which may optionally have substituents from the group of H, F, Cl, Br, I, OH, CF R12, R13, R14, R15, R16, R18 independently of one another H, (C or R12 and R13, R14 and R15 independently of one another, optionally together with the nitrogen atom to which they are bonded, a 5–6 membered ring which, apart from the nitrogen atom, may also include 0–1 further heteroatoms from the group of N-(C R17, R19, R20 independently of one another H, (C X a bond, a group of the formula —(CR21R22) Y O, CO, N(R23), S, SO, SO R21, R22 independently of one another H, (C y 1, 2, 3, 4, 5, 6; R23H, (C D, G CH or N; R2 OH, O—(C n 0, 1, 2, 3, 4; Q N(R24)(R25), or a 3 to 8-membered ring which may include 0 to 3 heteroatoms selected from the group of oxygen, nitrogen and sulfur, where the ring system may additionally be substituted by (C R26, R27, R28, R29, R30 independently of one another H, (C A a group of the formula —(C(R31)(R32)) m 0, 1, 2, 3, 4, 5; R31, R32, R33 independently of one another H, (C R24, R25 independently of one another H, (C o, 1, 2, 3, 4, 5, 6; q, s independently of one another 0, 1, 2, 3, 4; R34, R35 independently of one another H, (C R37, R38, R39, R40, R41, R42, R43, R44, R45, R46, R47, R48, R49, R50 independently of one another H, (C R39 and R40, R45 and R46, R49 and R50 independently of one another, optionally together with the nitrogen atom to which they are bonded a 5–6 membered ring which, apart from the nitrogen atom, may also include 0–1 further heteroatoms from the group of N-(C R36 OH, O—(C u 0, 1, 2; R51, 52 independently of one another H, (C R53, R54 independently of one another H, (C R55, R56 independently of one another H, (C R57H, (C R58 (C and the physiologically tolerated salts thereof.