Patent ID: 9072758
Filing Date: 2015-07-07
Classification: A61K,A61P,C07D,C07F

Abstract:
1. A compound selected from the following compound group: 5-[4-[[3-(2,6-dimethylphenyl)phenyl]methoxy]phenyl]-1,1-dioxo-1,2-thiazinan-3-one; 5-[4-[[3-(2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]phenyl]-1,1-dioxo-1,2-thiazinan-3-one; 4-(((1R)-1-(4-(1,1-dioxo-3-oxo-1,2-thiazinan-5-yl)phenoxy)-2,3-dihydro-1H-inden-4-yl)oxy)benzonitrile; 5-(4-(((R)-4-bromo-2,3-dihydro-1H-inden-1-yl)oxy)phenyl)-1,1-dioxo-1,2-thiazinan-3-one; 5-(4-(((R)-4-(4-(3-hydroxy-3-methylbutoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yl)oxy)phenyl)-1,1-dioxo-1,2-thiazinan-3-one; 5-[4-[[3-[6-(3-hydroxy-3-methylbutoxy)-2,4-dimethylpyridin-3-yl]phenyl]methoxy]phenyl]-1,1-dioxo-1,2-thiazinan-3-one 5-(4-(((R)-4-(6-(3-hydroxy-3-methylbutoxy)-2-methylpyridin-3-yl)-2,3-dihydro-1H-inden-1-yl)oxy)phenyl)-1,2-thiazinan-3-one 1,1-dioxide; 5-(4-(((R)-4-(2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yl)oxy)phenyl)-1,2-thiazinan-3-one 1,1-dioxide; 5-(4-(((R)-4-(2-(trifluoromethyl)phenyl)-2,3-dihydro-1H-inden-1-yl)oxy)phenyl)-1,2-thiazinan-3-one 1,1-dioxide; 5-(4-(((R)-4-(4-(2-ethoxyethoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yl)oxy)phenyl)-1,2-thiazinan-3-one 1,1-dioxide; 5-(4-(((R)-4-(4-(3-hydroxy-3-methylbutoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yl)oxy)phenyl)-1,2-thiazinan-3-one 1,1-dioxide; 5-(4-(((R)-4-(2,6-dimethyl-4-(3-(methylsulfonyl)propoxy)phenyl)-2,3-dihydro1H-inden-1-yl)oxy)phenyl)-1,2-thiazinan-3-one 1,1-dioxide; 5-(4-(((R)-4-(4-methoxy-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yl)oxy)phenyl)-1,2-thiazinan-3-one 1,1-dioxide; 5-(4-(((R)-4-(4-(3-hydroxy-3-methylbutoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yl)oxy)-2-methylphenyl)-1,2-thiazinan-3-one 1,1-dioxide; 5-(4-(((R)-4-phenoxy-2,3-dihydro-1H-inden-1-yl)oxy)phenyl)-1,2-thiazinan-3-one 1,1-dioxide; or a pharmaceutically acceptable salt of the compound, an optical isomer of the compound, or a pharmaceutically acceptable salt of the isomer.