Patent ID: 6664260
Filing Date: 2003-12-16
Classification: A61P,C07D

Abstract:
A compound of the formula (I): wherein:X is â€”CHR3â€”, â€”CHR3-alkyl-, or â€”CHR3-alkenyl-; R1 is selected from the group consisting of: -heteroaryl; -heterocyclyl; â€”R4-heteroaryl; and â€”R4-heterocyclyl; R2 is selected from the group consisting of: -hydrogen; -alkyl; -alkenyl; -aryl; -heteroaryl; -heterocyclyl; -alkyl-Y-alkyl; -alkyl-Y-alkenyl; -alkyl-Y-aryl; and -alkyl or alkenyl substituted by one or more substituents selected from the group consisting of: â€”OH; -halogen; â€”N(R3)2; â€”COâ€”N(R3)2; â€”COâ€”C1-10 alkyl; â€”COâ€”Oâ€”C1-10 alkyl; â€”N3; -aryl; -heteroaryl; -heterocyclyl; â€”CO-aryl; and â€”CO-heteroaryl; R4 is alkyl or alkenyl, which may be interrupted by one or more â€”Oâ€” groups; each R3 is independently H or C1-10 alkyl; each Y is independently â€”Oâ€” or â€”S(O)0-2â€”; n is 0 to 4; and each R present is independently selected from the group consisting of C1-10 alkyl, C1-10 alkoxy, hydroxy, halogen and trifluoromethyl; or a pharmaceutically acceptable salt thereof.