Patent ID: 8492373
Filing Date: 2013-07-23
Classification: A61K,A61P,C07D

Abstract:
1. A method of treating a disease or condition alleviated by a decrease in Axl activity in a mammal, wherein the method comprises administering to the mammal an effective amount of a compound of formula (I): wherein: R R or R or R each R each R each R each R each R each R as an isolated stereoisomer or a mixture thereof, or a pharmaceutically acceptable salt thereof, wherein the disease or condition is selected from breast carcinoma, renal carcinoma, endometrial carcinoma, ovarian carcinoma, thyroid carcinoma, non-small cell lung carcinoma, melanoma, prostate carcinoma, sarcoma, gastric cancer, uveal melanoma, myeloid leukemia and lymphoma.