Patent ID: 6410745
Filing Date: 2002-06-25
Classification: C07D

Abstract:
A process for preparing 1-guanylpyrazole acid adducts of the formula: wherein R1, R2 and R3 independently of one another are hydrogen, a branched or straight-chain C1-6-alkyl group, a C3-8-cycloalkyl group or a C6-12-aryl group which is unsubstituted of substituted by 1 to 6 alkyl groups; R4 is hydrogen or a straight-chain or branched C1-4-alkyl group; and X is Cl or Br, which comprises: conducting the reaction of pyrazole or a derivative thereof with cyanamide or a derivative thereof and gaseous hydrogen chloride or hydrogen bromide in an aprotic solvent, with the proviso that p-dioxane is excluded as an aprotic solvent.