Patent ID: 7041702
Filing Date: 2006-05-09
Classification: C07D

Abstract:
1. A compound that is: N-(4-methylbenzoyl)-N′-methyl-N′-(3-methylthiophenyl)guanidine; N-(4-methylbenzoyl)-N′-methyl-N′-(3-iodophenyl)guanidine; N-(4-methylbenzoyl)-N′-(1-naphthyl)guanidine; N-(4-methylbenzoyl)-N′-(4-benzyloxyphenyl)guanidine; N-(4-methylbenzoyl)-N′-(4-tertbutylphenyl)guanidine; N-(4-methylbenzoyl)-1-indolinylcarboximidamide; N-(4-methylbenzoyl)-N′-(4-isopropylphenyl)guanidine; N-(4-methylbenzoyl)-1-[7-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline] carboximidamide; N-(4-methylbenzoyl)-1-(1,2,3,4-tetrahydroquinoline)carboximidamide; N-(4-methylbenzoyl)-N′-(2,5-dibromophenyl)guanidine; N-(4-methylbenzoyl)-N′-(4-isopropoxyphenyl)guanidine; N-(4-methylbenzoyl)-N′-(3,4,5-trimethoxyphenyl)guanidine; N-(4-methylbenzoyl)-N′-(2-isopropylphenyl)guanidine; N-(2,5-dichlorobenzoyl)-N′-methyl-N′-(3-iodophenyl)guanidine; N-(2,5-dichlorobenzoyl)-N′-methyl-N′-(3-methylthiophenyl)guanidine; N-(2,5-dichlorobenzoyl)-N′-(1-naphthyl)guanidine; N-(2,5-chlorobenzoyl)-N′-(4-benzyloxyphenyl)guanidine; N-(2,5-dichlorobenzoyl)-N′-(4-isopropylphenyl)guanidine; N-(2,5-dichlorobenzoyl)-N′-(4-tertbutylphenyl)guanidine; N-(2,5-dichlorobenzoyl)-1-indolinylcarboximidamide; N-(2,5-dichlorobenzoyl)-N′-methyl-N′-(4-isopropylphenyl)guanidine; N-(phenylacetyl)-N′-(4-benzyloxyphenyl)guanidine; N-(phenylacetyl)-N′-(4-isopropylphenyl)guanidine; N-(phenylacetyl)-N′-(4-tert-butylphenyl)guanidine; N-(phenylacetyl)-1-indolinylcarboximidamide; N-(phenylacetyl)-1-(1,2,3,4-tetrahydroquinoline)carboximidamide; N-(phenylacetyl)-N′-(4-isopropoxyphenyl)guanidine; N-(phenylacetyl)-N′-(4-isopropylphenyl)-N′-methylguanidine; N-(adamantan-1-carbonyl)-N ‘-methyl-N’-(3-iodophenyl)guanidine; N-(adamantan-1-carbonyl)-N′-(1-naphthyl)guanidine; N-(adamantan-1-carbonyl)-N′-(4-benzyloxyphenyl)guanidine; N-(adamantan-1-carbonyl)-N′-(4-isopropylphenyl)guanidine; N-(adamantan-1-carbonyl)-N′-(4-tert-butylphenyl)guanidine; N-(adamantan-1-carbonyl)-1-(indolinyl)carboximidamide; N-(adamantan-1-carbonyl)-1-(1,2,3,4-tetrahydroquinolinyl)carboximidamide; N-(adamantan-1-carbonyl)-N′-(2,5-dibromophenyl)guanidine; N-(adamantan-1-carbonyl)-N′-(4-isopropylphenyl)-N′-methyl)guanidine; N-(4-chlorobenzoyl)-N′-methyl-N′-(3-iodophenyl)guanidine; N-(4-chlorobenzoyl)-N′-methyl-N′-(3-methylthiophenyl)guanidine; N-(4-chlorobenzoyl)-N′-(1-naphthyl)guanidine; N-(4-chlorobenzoyl)-N′-(4-benzyloxyphenyl)guanidine; N-(4-chlorobenzoyl)-N′-(4-isopropylphenyl)guanidine; N-(4-chlorobenzoyl)-N′-(4-tert-butylphenyl)guanidine; N-(4-chlorobenzoyl)-1-(indolinyl)carboximidamide; N-(4-chlorobenzoyl)-1-(1,2,3,4-tetrahydroquinolinyl)carboximidamide; N-(4-chlorobenzoyl)-N′-(2,5-dibromophenyl)guanidine; N-(3,4-dichlorobenzoyl)-N′-methyl-N′-(3-iodophenyl)guanidine; N-(3,4-dichlorobenzoyl)-N′-(1-naphthyl)guanidine; N-(3,4-dichlorobenzoyl)-N′-(4-benzyloxyphenyl)guanidine; N-(3,4-dichlorobenzoyl)-N′-(4-isopropylphenyl)guanidine; N-(3,4-dichlorobenzoyl)-N′-(4-tert-butylphenyl)guanidine; N-(3,4-dichlorobenzoyl)-1-(indolinyl)carboximidamide; N-3,4-dichlorobenzoyl)-1-(1,2,3,4-tetrahydroquinolinyl)carboximidamide; N-(3,4-dichlorobenzoyl)-N′-methyl-N′-(4-isopropylphenyl)guanidine; N-(thiophen-2-carbonyl)-N′-methyl-N′-(3-iodophenyl)guanidine; N-(thiophen-2-carbonyl)-N′-methyl-N′-(3-methylthiophenyl)guanidine; N-(thiophen-2-carbonyl)-N′-(1-naphthyl)guanidine; N-(thiophen-2-carbonyl)-N′-(4-benzyloxyphenyl)guanidine; N-(thiophen-2-carbonyl)-N′-(4-isopropylphenyl)guanidine; N-(thiophen-2-carbonyl)-N′-(4-tert-butylphenyl)guanidine; N-(thiophen-2-carbonyl)-1-(indolinyl)carboximidamide; N-(thiophen-2-carbonyl)-1-(1,2,3,4-tetrahydroquinolinyl)carboximidamide; N-(thiophen-2-carbonyl)-N′-methyl-N′-(4-isopropylphenyl)guanidine; N-(furan-2-carbonyl)-N′-methyl-N′-(3-iodophenyl)guanidine; N-(furan-2-carbonyl)-N′-methyl-N′-(3-methylthiophenyl)guanidine; N-(furan-2-carbonyl)-N′-(1-naphthyl)guanidine; N-(furan-2-carbonyl)-N′-(4-benzyloxyphenyl)guanidine; N-(furan-2-carbonyl)-N′-(4-isopropylphenyl)guanidine; N-(furan-2-carbonyl)-N′-(4-tert-butylphenyl)guanidine; N-(furan-2-carbonyl)-1-(indolinyl)carboximidamide; N-(furan-2-carbonyl)-1-(1,2,3,4-tetrahydroquinolinyl)carboximidamide; N-(furan-2-carbonyl)-N′-(4-isopropylphenyl)-N′-methylguanidine; N-(pyridin-3-carbonyl)-N′-(1-naphthyl)guanidine; N-(pyridin-3-carbonyl)-N′-(4-benzyloxyphenyl)guanidine; N-(pyridin-3-carbonyl)-N′-(4-isopropylphenyl)guanidine; N-(pyridin-3-carbonyl)-N′-(4-tert-butylphenyl)guanidine; N-(pyridin-3-carbonyl)-1-(indolinyl)carboximidamide; N-(pyridin-3-carbonyl)-1-(1,2,3,4-tetrahydroquinolinyl)carboximidamide; N-(4-methoxybenzoyl)-N′-(4-benzyloxyphenyl)guanidine; N-(4-methoxybenzoyl)-N′-(4-isopropylphenyl)guanidine; N-(4-methoxybenzoyl)-N′-(4-isopropoxyphenyl)guanidine; N-(4-methoxybenzoyl)-N′-(3,4,5-trimethoxyphenyl)guanidine; N-(1-naphthoyl)-N′-(4-benzyloxyphenyl)guanidine; N-(1-naphthoyl)-N′-(4-isopropylphenyl)guanidine; N-(1-naphthoyl)-N′-(4-isopropoxyphenyl)guanidine; N-(3,4,5-trimethoxybenzoyl)-N′-(2-isopropylphenyl)guanidine; N-(3,4,5-trimethoxybenzoyl)-N′-(4-isopropoxyphenyl)guanidine; N-(4-butoxybenzoyl)-N′-(2-isopropylphenyl)guanidine; N-(4-butoxybenzoyl)-N′-(4-isopropoxyphenyl)guanidine; N-(4-butoxybenzoyl)-N′-(3,4,5-trimethoxyphenyl)guanidine; N-(4-ethoxybenzoyl)-N′-(2-isopropylphenyl)guanidine; N-(4-ethoxybenzoyl)-N′-(4-isopropoxyphenyl)guanidine; N-(4-methylbenzoyl)-N′-(benzyl)guanidine; N-(4-methylbenzoyl)-N′-(2-phenethyl)guanidine; N-(4-methylbenzoyl)-N′-(3-dimethylaminopropyl)guanidine; N-(4-methylbenzoyl)-N′-(4-phenylbutyl)guanidine; N-(4-methylbenzoyl)-N′-(3-phenylpropyl)guanidine; N-(4-methylbenzoyl)-N′-(1-naphthylmethyl)guanidine; N-(4-methylbenzoyl)-N′-(2-(4-chlorophenyl)ethyl)guanidine; N-(4-methylbenzoyl)-N′-(5-phenylpentyl)guanidine; N-(4-methylbenzoyl)-N′-(3-phenoxypropyl)guanidine; N-(3,4-dichlorobenzoyl)-N′-(3-phenylpropyl)guanidine; N-(4-chlorobenzoyl)-N′-(4-phenylbutyl)guanidine; N-(4-methoxybenzoyl)-N′-(3-dimethylaminopropyl)guanidine; N-(4-methoxybenzoyl)-N′-(4-phenylbutyl)guanidine; N-(4-methoxybenzoyl)-N′-(2-(4-chlorophenylethyl)guanidine; N-(4-methoxybenzoyl)-N′-(1-naphthylmethyl)guanidine; N-(4-methoxybenzoyl)-N′-(3,4,5-trimethoxybenzyl)guanidine; N-(4-ethoxybenzoyl)-N′-(4-phenylbutyl)guanidine; N-(4-ethoxybenzoyl)-N′-(2-phenethyl)guanidine; N-(4-ethoxybenzoyl)-N′-(2-(4-chlorophenyl)guanidine; N-(4-ethoxybenzoyl)-N′-(3-phenylpropyl)guanidine; N-(4-ethoxybenzoyl)-N′-(1-naphthylmethyl)guanidine; N-(4-butoxybenzoyl)-N′-(4-phenylbutyl)guanidine; N-(4-butoxybenzoyl)-N′-(2-phenethyl)guanidine; N-(4-butoxybenzoyl)-N′-(2-(4-chlorophenyl)ethyl)guanidine; N-(4-butoxybenzoyl)-N′-(3-phenylpropyl)guanidine; N-(4-butoxybenzoyl)-N′-(2-(3-indole)ethyl)guanidine; N-(3,4,5-trimethoxybenzoyl)-N′-(4-phenylbutyl)guanidine; N-(3,4,5-trimethoxybenzoyl)-N′-(2-(3-indole)ethyl)guanidine; N-(1-naphthoyl)-N′-(benzyl)guanidine; N-(1-naphthoyl)-N′-(3-dimethylaminopropyl)guanidine; N-(1-naphthoyl)-N′-(2-phenylethyl)guanidine; N-(1-naphthoyl)-N′-(4-phenylbutyl)guanidine; N-(thiophen-2-carbonyl)-N′-(benzyl)guanidine; N-(thiophen-2-carbonyl)-N′-(3-dimethylaminopropyl)guanidine; N-(thiophen-2-carbonyl)-N′-(2-phenylethyl)guanidine; N-(thiophen-2-carbonyl)-N′-(4-phenylbutyl)guanidine; N-(4-methylbenzoyl)-N′-(cyclohexyl)-N″-methylguanidine; N-(4-methylbenzoyl)-N′-(4-phenylbutyl)-N″-methylguanidine; N-(4-methoxybenzoyl)-N′-(5-phenylpentyl)guanidine; N-(2-methylbenzoyl)-N′-(4-phenylbutyl)guanidine; N-(2-methylbenzoyl)-N′-(2-isopropylphenyl)guanidine; N-(2-methylbenzoyl)-N′-(4-isopropylphenyl)guanidine; N-(2-methylbenzoyl)-N′-(3-phenylpropyl)guanidine; N-(4-methoxybenzoyl)-N′-(2-phenoxypropyl)guanidine; N-(4-butoxybenzoyl)-N′-(5-phenylpentyl)guanidine; N-(4-methylbenzoyl)-N′-(2-phenoxyethyl)guanidine; N-(4-methoxybenzoyl)-N′-(2-phenoxyethyl)guanidine; N-(4-ethoxybenzoyl)-N′-[(2-benzylthio)ethyl]guanidine; N-(4-ethoxybenzoyl)-N′-(3,4,5-trimethoxyphenyl)guanidine; or a pharmaceutically acceptable salt of any of said compounds.