Patent ID: 7528175
Filing Date: 2009-05-05
Classification: A61K,A61P,Y10S

Abstract:
1. A method for the treatment of a disease or condition treatable by chronic administration of a β-adrenergic inverse agonist, the disease or condition being a respiratory disease or condition, wherein the respiratory disease or condition is asthma, comprising the steps of: (a) selecting an initial low dose of nadolol; (b) administering the dose of the nadolol to a patient with the respiratory disease or condition; (c) monitoring the response of the patient to the initial dose according to one or more preset criteria that indicates the response of the patient to the dose; (d) if the response to the dose is favorable, subsequently administering a higher dose of the nadolol; (e) repeating steps (b)-(d) with the higher dose until the maximum tolerated dose is attained; and (f) maintaining the patient on the maximum tolerated dose.