Patent ID: 7241584
Filing Date: 2007-07-10
Classification: C07K,C12N,Y10S

Abstract:
1. An isolated and purified nucleic acid molecule encoding a thermostable luciferase variant that retains at least 50% activity in aqueous solution for at least 2 hours at a temperature of about 50° C., wherein the nucleic acid molecule comprises a nucleic acid segment comprising SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO:6, SEQ ID NO:7, SEQ ID NO:8, SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:13, SEQ ID NO:42, SEQ ID NO:46, or SEQ ID NO:43, or a portion thereof encoding a protein with the luminescent activity of a protein having SEQ ID NO:14, SEQ ID NO:15, SEQ ID NO:16, SEQ ID NO:17, SEQ ID NO:18, SEQ ID NO:19, SEQ ID NO:20, SEQ ID NO:21, SEQ ID NO:22, SEQ ID NO:23, SEQ ID NO:24, SEQ ID NO:26, SEQ ID NO:44, SEQ ID NO:47, or SEQ ID NO:45.