Patent ID: 6133047
Filing Date: 2000-10-17
Classification: B03C,G01N,H01F,Y10S,Y10T

Abstract:
Monodisperse superparamagnetic particles having a predetermined size of between 0.1 and 10 .mu.m, comprising:a core based on a first polymer,an internal layer, called the magnetic layer, covering the core, based on a second polymer, wherein in said internal layer a magnetic material is distributed, andan external layer, called the encapsulation layer, optionally functionalized, covering the magnetic layer, based on a third polymer and having an ability to interact with at least one biological molecule to fix the at least one biological molecule to the particles, either directly or indirectly,wherein at least the second polymer is heat-sensitive and has a predetermined lower critical solubility temperature (LCST) of between 15 and 65.degree. C.