Patent ID: 8809367
Filing Date: 2014-08-19
Classification: A61P,C07D

Abstract:
1. A method of treating a disorder associated with N-formyl peptide receptor like-1 (FPRL-1) receptor modulation, selected from: ocular inflammatory diseases, wet and dry age-related macular degeneration (ARMD), uveitis, dry eye, Keratitis, allergic eye disease, conditions affecting the posterior part of the eye, maculopathies, retinal degeneration, non-exudative age related macular degeneration, exudative age related macular degeneration, choroidal neovascularization, diabetic retinopathy, retinopathy of prematurity (ROP), acute macular neuroretinopathy, central serous chorioretinopathy, cystoid macular edema, diabetic macular edema, infectious keratitis, herpetic keratitis, corneal angiogenesis, lymphangiogenesis, retinitis and post-surgical corneal wound healing, which comprises administering to a mammal in need thereof, a pharmaceutical composition comprising a therapeutically effective amount of at least one compound of Formula I wherein: A is C R B is C R R R R R R R R R R R R R X is O or S; Y is O or S; R R R R R R n is 1-4; and m is 1-4.