Patent ID: 8138359
Filing Date: 2012-03-20
Classification: C07D

Abstract:
1. A composition comprising: an isolated 3-hydroxyflavan adduct in which a reducing agent, selected from the group consisting of a N-substituted cysteine, glutathione, dithiothreitol, dithioerythrol, mercaptoethanol, and Tris(2-carboxyethyl)phosphine, is covalently bound to a B-ring of the 3-hydroxyflavan, with the proviso that (a) where the 3-hydroxyflavan is catechin, then the reducing agent is not glutathione or glutamine-cysteine dipeptide; (b) where the 3-hydroxyflavan is epicatechin, then the reducing agent is not dithiothreitol or glutamine-cysteine dipeptide.