Patent ID: 8679546
Filing Date: 2014-03-25
Classification: A23K,A61K

Abstract:
1. A granule for animal feed for a ruminant with controlled release of a physiologically active substance, said granule comprising a core, a first layer surrounding the core, and a second layer surrounding the first layer, said core comprising a matrix along with one or more physiologically active substances selected from the group consisting of amino acids, vitamins, enzymes, proteins, carbohydrates, probiotic micro-organisms, prebiotic foods, mineral salts, choline, choline chloride, choline bi-tartrate, di-hydrogenated citrate of choline, bicarbonate of choline, choline sulphate, choline hydroxide, vitamin C acetate, and organic acids, said matrix comprising carnauba wax and/or microcrystalline wax, the layers together being effective to protect the physiologically active substance from ruminal activity while allowing effective release of the physiologically active substance into the post-rumen portion of the digestive tract of the ruminant, the first layer comprising a first hydrophobic substance selected from the group consisting of fats, fatty acids, hydrogenated oils, mono- and di-glycerides of fatty acids, esters of fatty acids, fatty alcohols, with chains from 12 to 22 atoms of carbon and a melting point of from 40 to 74° C., said first layer providing an effective water-repellent film that is stable under the conditions in the rumen for at least 8 hours, the second layer consisting of a second hydrophobic substance selected from the group consisting of microcrystalline waxes, paraffin waxes, vegetable waxes and synthetic waxes, the second layer having a melting point of from 80 to 100° C., said second layer being effective to protect the core and the first layer from degradation from pressure, impact and mechanical and thermal stress encountered during mixing and pelletization of said granules into an animal feed pellet.