Patent ID: 6589750
Filing Date: 2003-07-08
Classification: A61K,A61P,C07K,Y10S

Abstract:
A method for screening ligands that bind to a receptor of an XQHNPR peptide (SEQ ID NOS:1-7 and 12), comprising the steps of:a) preparing a cell culture, organ specimen or tissue sample expressing a receptor of an XQHNPR peptode (SEQ ID NOS:1-7 and 12); b) adding a candidate molecule in the presence of a half-saturating concentration of a labeled XQHNPR peptide (SEQ ID NOS:1-7 and 12) to said cell culture, organ specimen or tissue sample said culture, specimen or sample are cells involved in mineral ion balance; c) incubating said cell culture, organ specimen or tissue sample in the presence of said candidate molecule and said labeled XQHNPR peptide (SEQ ID NOS:1-7 and 12) for a time sufficient for specific binding to take place between said cell culture, organ specimen or tissue sample and said candidate molecule and said labeled XQHNPR peptide (SEQ ID NOS:1-7 and 12); and d) quantifying the label specifically bound to said cell culture, organ specimen or tissue sample.