Patent ID: 6025370
Filing Date: 2000-02-15
Classification: A61P,C07D,C07F

Abstract:
A quinolonecarboxylic acid derivative represented by the general formula, or its salt: ##STR8## wherein R.sup.1 represents a hydrogen atom or a carboxyl-protecting group; R.sup.2 represents a substituted or unsubstituted alkyl, alkenyl, cycloalkyl, aryl or heterocyclic group; R.sup.3 is selected from the group consisting of a hydrogen atom, halogen atom, a substituted or unsubstituted alkyl, alkenyl, cycloalkyl, aryl, alkoxy or alkylthio group, a nitro group, a cyano group, an acyl group, a protected or unprotected hydroxyl group, and a protected or unprotected, or substituted or unsubstituted amino group; R.sup.4 is selected from the group consisting of a hydrogen atom, a halogen atom, a substituted or unsubstituted alkyl, alkenyl, cycloalkyl, aralkyl, aryl, alkoxy or alkylthio group, a protected or unprotected hydroxyl or imino group, a protected or unprotected, or substituted or unsubstituted amino group, an alkylidene group, an oxo group and a group forming a cycloalkane ring together with the carbon atom to which R.sup.4 is bonded; R.sup.5 represents a hydrogen atom or a substituted or unsubstituted alkyl, cycloalkyl, alkylsulfonyl, arylsulfonyl, acyl or aryl group; R.sup.6 represents a hydrogen atom, a halogen atom, a substituted or unsubstituted alkyl, alkoxy or alkylthio group, a protected or unprotected hydroxyl or amino group, or a nitro group; and A represents CH or C-Y in which Y represents a halogen atom, a substituted or unsubstituted alkyl, alkoxy or alkylthio group, or a protected or unprotected hydroxyl group.