Patent ID: 6584349
Filing Date: 2003-06-24
Classification: A61N

Abstract:
An anode electrode for an iontophoretic device useful for delivering a medicament comprising:an electrode compartment, said electrode compartment including an electrolyte comprising a medicament and an anode electrode in electrical communication with said electrolyte, said anode electrode including: at least two electrochemically active, dissimilar metals such that a first chemically inert metal provides a coating having a thickness of about 0.1 mil over a second metal, said chemically inert first metal substantially preventing a chemical reaction of said second metal with said electrolyte containing said medicament during shelf storage and a skin contacting compartment which is in ionic communication with said electrode compartment; and an ion exchange material selected to capture positive ions of said second metal liberated by an electrochemical reaction during a use of said iontophoretic device to deliver said medicament, wherein said chemically inert first metal is substantially removed during said electrochemical reaction during an initial use of said device, said second metal thereby serving as the active electrode during subsequent delivery of said medicament.