Patent ID: 7232903
Filing Date: 2007-06-19
Classification: C07C,C07D

Abstract:
1. A process for preparing quinazolin-4-one or a derivative thereof having the formula (2): in which each of R 1 , R 2 , R 3 and R 4 independently represents a hydrogen atom, a halogen atom, or a group selected from the group consisting of alkyl, cycloalkyl, aralkyl, aryl, hydroxyl, alkoxy, alkylthio, nitro, and cyano, wherein a compound having the formula (1): in which each of R 1 , R 2 , R 3 and R 4 has the same meaning as above, is reacted with a formic acid ester or an orthoformic acid ester at a temperature in the range of 50 to 150° C. in the presence of ammonia.