Patent ID: 8877814
Filing Date: 2014-11-04
Classification: A61K,A61P

Abstract:
1. A method of treating tinnitus, in a subject in need thereof, comprising administration of a therapeutically effective amount of a 1-amino-alkylcyclohexane derivative selected from neramexane and pharmaceutically acceptable salts thereof, wherein the 1-amino-alkylcyclohexane derivative is administered in a titration scheme comprising up titration of the 1-amino-alkylcyclohexane derivative in increasing dosages of 25 mg or 12.5 mg steps at weekly intervals over a period of four weeks to achieve a body weight-adjusted target dose of 50 mg/day for patients with a body weight of up to 90 kg, or over a period of five weeks to achieve a body weight-adjusted target dose of 75 mg/day for patients with a body weight of equal to or greater than 90 kg.