Patent ID: 7700364
Filing Date: 2010-04-20
Classification: G01N

Abstract:
1. A method for identifying the presence of one or more free amino acids in a body fluid of an individual, comprising: (a) derivatizing free amino acids in the body fluid; (b) separating the derivatized free amino acids by liquid chromatography (LC); (c) subjecting the separated derivatized free amino acids from step (b) to mass spectroscopic (MS) analysis using a mass spectrometer to identify derivatized free amino acids from the body fluid by comparison to structurally similar amino acids from a set of free amino acid standards, wherein the identified derivatized free amino acids include one or more free amino acids selected from the group consisting of phosphoserine, sulfocysteine, phosphoethanolamine, carnosine, anserine, 1,3-methyl-histidine, L-allo-cystathionine-A, and DL-allo-hydroxylysine, wherein said MS is other than tandem MS.