Patent ID: 8715638
Filing Date: 2014-05-06
Classification: A61P,C07D

Abstract:
1. A compound, or a pharmaceutically acceptable salt thereof, said compound having the general structure shown in Formula (I.a.10.j): wherein: CB is a moiety selected from the group consisting of: wherein each R 10 is independently selected from the group consisting of methyl, ethyl, and cyclopropyl; X is N; Y is N; R Z is selected from the group consisting of H, methyl, and chloro; R is unsubstituted phenyl or phenyl substituted with from 1 to 4 substituents independently selected from the group consisting of alkyl, cycloalkyl, alkoxy, halo, —CN, —NH or, alternatively, R is unsubstituted heteroaryl or heteroaryl substituted with from 1 to 3 substituents independently selected from the group consisting of alkyl, alkoxy, cycloalkyl, halo, —CN, —NH R each R each R wherein each said alkyl, each said alkoxy, each said alkenyl, each said haloalkyl, each said heteroalkyl, each said heterohaloalkyl, each said alkylamino, each said alkylthio, each said heteroalkenyl, each said haloalkenyl, each said —S(O) each R wherein each said alkyl, each said alkoxy, each said alkenyl, each said haloalkyl, each said heteroalkyl, each said heterohaloalkyl, each said alkylamino, each said alkylthio, each said heteroalkenyl, each said haloalkenyl, each said —S(O) or, alternatively, R