Patent ID: 6303118
Filing Date: 2001-10-16
Classification: A61K,A61P,C12N,C12Y,Y02A

Abstract:
A method of therapeutic or prophylactic treatment of a human individual against infection by a chitin-containing pathogen, comprising administering to said human individual a pharmaceutical composition comprising a substantially isolated or purified chitinase and a pharmaceutically acceptable carrier or diluent, said chitinase being a human chitinase having the amino acid sequence of SID NO:4 or SID NO:6 or a human chitinase having chitinase activity, which is encoded by a nucleic acid which hybridizes to SID NO:3 or SID NO:5 at 65.degree. C., in 1 mM EDTA, 0.5 M sodium hydrogen phosphate (pH 7.2) containing 7% (w/v) SDS.