Patent ID: 8007785
Filing Date: 2011-08-30
Classification: A61K,A61P

Abstract:
1. A method for treating a patient suffering from colon cancer, the method comprising: i) identifying in a patient one or more sentinel or metinel lymph nodes draining a tumour in the colon or a metastasis from a tumour in the colon; ii) resecting the one or more lymph nodes and, optionally all or part of the tumour or metastasis; iii) isolating tumour-reactive T-lymphocytes from said lymph nodes; iv) in vitro expanding said tumour-reactive T-lymphocytes, wherein the in vitro expansion comprises v) administering tumour-reactive T-lymphocytes obtained in step (iv) to the patient; wherein the T-lymphocytes are CD4+ helper or CD8+ T-lymphocytes and are not CD4+ CD25+