Patent ID: 9216959
Filing Date: 2015-12-22
Classification: A61K,A61P,C07D,Y10S

Abstract:
1. A pharmaceutical composition comprising a compound of formula: or a pharmaceutically acceptable salt thereof, wherein: R X is a halogen; Y is O, S, or NH; Z is O or S; and n is an integer from 0 to 5 and m is 0 or 1, wherein m+n is less than or equal to 5; and a cardiovascular drug chosen from a peripheral anti-adrenergic drug, a centrally acting antihypertensive drug, an antihypertensive direct vasodilator, a drug affecting renin-angiotensin system, a peripheral vasodilator, an antianginal drug, a cardiac glycoside, an inodilator, an antidysrhythmic drug, a calcium entry blocker, ranitine, bosentan, rezulin, and phentolamine.