Patent ID: 7452907
Filing Date: 2008-11-18
Classification: A61K,A61P,C07D

Abstract:
1. A compound which has the structure wherein X m is a bond, C 1-2 alkylene, C 2 alkenylene, allenyl or C 2 alkynylene; X Q is C or N; A is C wherein X X X X in each of X R R R R Y is CO Z is (CH including all stereoisomers thereof, and a pharmaceutically acceptable salt thereof, wherein the term prodrug ester refers to carboxylic acid esters, phosphorus acid esters, and esters where R wherein R a , R b and R c are H, alkyl, aryl or arylalkyl; provided that R a O cannot be HO, or R 4 is wherein R a is H, alkyl, arylalkyl or aryl; R d is H, alkyl, halogen or alkoxy, R e is alkyl, aryl, arylalkyl or alkoxyl, and n 1 is 0, 1 or 2.