Patent ID: 6426421
Filing Date: 2002-07-30
Classification: C07H,Y02P

Abstract:
A method of protecting a functional group as depicted in Scheme 51: whereinX represents Cl, Br, I, OTf, OTs, ONf, or OMs; Z represents Cl, Br, or I; Ar represents an optionally substituted monocyclic or polycyclic aryl or heteroaryl group, wherein CH2X and Z are bonded to the same aromatic ring of Ar; M represents O, S, or NR; R represents independently for each occurrence H, alkyl, aryl or heteroaryl; D represents alkyl, aryl, heteroaryl, furanosyl, acyl, or (RO)2P(O)â€”; and base is absent or represents a carbonate, bicarbonate or hydride.