Patent ID: 9101857
Filing Date: 2015-08-11
Classification: A01N,B01D,C07K,C12M,C12N

Abstract:
1. A gas-scrubbed filtration device to remove a liquid from a suspension comprising: (a) at least one perfusion filter, wherein the perfusion filter is a tube or cylinder, and wherein at least one surface and connected to a source of vacuum through a harvest tube and disposed in the suspension; (b) at least one sparging filter, wherein the sparging filter is a tube or a cylinder, connected to a source of compressed gas and capable of blowing gas bubbles of 10-1000 micron diameter in size and disposed in the suspension; (c) fixing the perfusion filter and the sparging filter in such configuration as to allow optimal contact of gas bubbles from sparging filter with the surface of the perfusion filter, wherein the perfusion filters and the sparging filter are set apart at least 10 μm to no more than 50 mm along the entire surface of the perfusion filter and sparging filter; (d) a vacuum source to maintain a level of vacuum needed to draw a pre-determined volume of the liquid out of the suspension; (e) and wherein the source of compressed gas comprises an adjustable flow rate valve to adjust the flow rate of gas thereby increasing or decreasing scrubbing at the surface of the perfusion filter.