Patent ID: 6284474
Filing Date: 2001-09-04
Classification: C07K,G01N

Abstract:
A method for detecting lung injury in a human subject, the method comprising the steps of:contacting a specific anti-human type I alveolar cell monoclonal antibody with a test sample from a subject suspected of having acute lung injury, wherein the sample is suspected of comprising a human type I alveolar cell-specific polypeptide; anddetecting specific binding of the anti-human type I alveolar cell monoclonal antibody to the human type I alveolar cell-specific polypeptide in the sample;wherein detection of specific binding of the anti-human type I alveolar cell monoclonal antibody to human type I alveolar cell-specific polypeptide in the sample at a level substantially elevated relative to a level in a normal subject is indicative of acute lung injury in the subject.