Patent ID: 9066853
Filing Date: 2015-06-30
Classification: A61B,A61K,A61L

Abstract:
1. An implantable fiber for reducing or treating pain in a patient in need of such treatment, the implantable fiber comprising a memory shape fiber and having a first end and a second end, and at least a portion configured to be wrapped around or sutured to a target tissue site beneath the skin of the patient, wherein said implantable fiber comprises clonidine in an amount from about 0.1 wt. % to about 40 wt. % of the implantable fiber, and at least one biodegradable polymer, and wherein the implantable fiber comprises (i) a burst release surface configured to release at a site beneath the skin a bolus dose of the clonidine in an amount of from about 10% to about 50% of the clonidine during the first 24 hours after implantation and (ii) a sustain release layer configured to release an effective amount of the clonidine over an additional period of at least three days.