Patent ID: 9012182
Filing Date: 2015-04-21
Classification: C07K,C12P

Abstract:
1. A method for producing a purine nucleotide comprising: (a) cultivating a bacterium belonging to the genus (b) phosphorylating the purine nucleoside to generate a purine nucleotide, and (c) collecting said purine nucleotide, wherein said bacterium has a purine nucleoside-producing ability and has been modified to have enhanced activity of a YdhL protein by a method selected from the group consisting of: (A) transforming the bacterium with a multi-copy vector containing a ydhL gene and/or introducing multiple copies of the ydhL gene into chromosome of the bacterium, (B) placing the ydhL gene under the control of a promoter capable of enhancing the expression of the ydhL gene, and (C) combinations thereof.