Patent ID: 8932637
Filing Date: 2015-01-13
Classification: A61K,A61L

Abstract:
1. A method of treating urinary incontinence or urinary reflux disease, comprising: injecting a composition comprising substantially spherical microspheres in a biocompatible carrier to a bladder sphincter muscle or urethra muscle of a mammal, wherein the microspheres are non-biodegradable, non-aggregating, and do not clump together, and wherein the microspheres are swellable up to about 4 times their non-swollen diameter or up to about 15 times their non-swollen volume; and reducing an internal lumen of the bladder sphincter muscle or urethra muscle with the composition as a tissue bulking agent, wherein the microspheres comprise at least one of a sodium acrylate polymer, sodium acrylate and vinyl alcohol copolymer, acrylamide polymer, acrylamide derivative polymer, acrylamide derivative copolymer, or mixtures thereof.