Patent ID: 6603021
Filing Date: 2003-08-05
Classification: C07D

Abstract:
A method of making a compound having the formula (C) below: wherein R1, R2, R4, and R5 are, independently, H or a C1 to C6 alkyl or substituted alkyl; and wherein R3 is H or a C1 to C6 alkyl or substituted alkyl; the method comprising reacting an initial compound with an alcohol and hydrogen in the presence of water and a catalyst, the initial compound having the formula (B) below: wherein R1, R2, R4, and R5 are, independently, H or a C1 to C6 alkyl or substituted alkyl, or wherein R2 and R4 together are replaced by a double bond; R3 is H or a C1 to C6 alkyl or substituted alkyl; and X and Y are, independently, OH, Oâˆ’, or where X and Y together are a bridging oxo; andwherein the catalyst comprises carbon, metal oxide and at least one metal selected from the group consisting of Pd, Rh, Pt, Ru, Ni and Co.