Patent ID: 6660300
Filing Date: 2003-12-09
Classification: A61K,A61P,Y10S

Abstract:
A method for treating diabetes comprising administering once daily to a mammalian patient in need of treatment a therapeutically effective amount of a pharmaceutical formulation comprising (1) an inner solid particulate phase, and (2) an outer solid continuous phase in which particles of said inner solid particulate phase are dispersed and embedded, the particles of said inner solid particulate phase comprising (a) a pharmaceutical having a high water solubility selected from metformin or a pharmaceutically acceptable salt thereof; and (b) an extended release material, and said outer solid continuous phase comprising an extended release material, wherein the total extended release material content in both said inner solid particulate phase and said outer continuous phase is within the range from about 25 to about 75% by weight of the pharmaceutical formulation.