Patent ID: 6429207
Filing Date: 2002-08-06
Classification: C07D

Abstract:
A compound represented by the formula I,R&Brketopenst;Linker&Brketclosest;Ar wherein R is an optionally substituted straight or branched chain alkyl, aralkyl, cycloalkyl, or alkylcycloalkyl group containing 5-12 carbon atoms, wherein Ar is a quinoxaline moiety with 0-2 substituents, wherein the quinoxaline substituents are selected from the group consisting of F, Cl, Br, or I at the 3 position, and C1-C3 alkyl and F, Cl, Br, or I at the 5, 6, 7, and 8 positions, and wherein [linker] is â€”(CH2)nâ€”, where n is 2-6, and wherein up to 4 CH2 groups may independently be replaced with groups selected from the group consisting of C1-C3 alkyl, CHOH, CO, O, S, SO, SO2, N, NH, and NO, provided that two heteroatoms may not be adjacent except when those atoms are both N or are both NH, and wherein any two adjacent CH2 groups may be replaced by a substituted or unsubstituted alkene or alkyne group, or a pharmaceutically acceptable salt thereof.