Patent ID: 6946145
Filing Date: 2005-09-20
Classification: C08G,Y10S

Abstract:
1. A micellar pharmaceutical composition for the delivery of a hydrophobic or water-insoluble active agent, comprising the active agent physically entrapped within but not covalently bonded to a drug carrier comprising a block copolymer of formula X, formula Y, or formula Z: where: R R f and h are independently an integer from 2 to 1000; g and j are independently an integer from 2 to 200; POE is a poly(ortho ester) unit of formula IA or formula IIA: where R* is a C R is a bond, —(CH each A is independently selected from R R where: p is an integer of 1 to 20; R R where: s is an integer of 0 to 30; t is an integer of 2 to 200; and R R R where: x is an integer of 0 to 30; y is an integer of 2 to 200; R R R R in which at least 0.1 mol % of the A units are R