Patent ID: 6274736
Filing Date: 2001-08-14
Classification: A61P,C07B,C07D,G01N

Abstract:
A process for the chromatographic separation of a mixture of enantiomers of a lactone ##STR5##into separate enantiomers thereof, said process comprising separating the separate enantiomers from a mobile phase comprising a mixture of the enantiomers by means of a chiral stationary phase comprising A) an optically active polymer selected from the group consisting of an optically active polymer of N-acryloyl-S-phenylalanine d-neomenthyl-amide and an optically active polymer of an enantiomer of N-acryloyl-S-phenylalanine d-neomenthyl-amide, B) a crosslinked form of said optically active polymer and/or C) a carrier-bonded form of said polymer.