Patent ID: 7217705
Filing Date: 2007-05-15
Classification: A61K,A61P

Abstract:
1. A composition comprising a dopaminergic agonist and of one or more CB1 antagonist azetidine derivatives of formula I: wherein either A: R is CR  R  R R R R R R R R R R R R R R R R R R —NR R R R R R R R R R R R Ar Het or B: wherein R is CHR R Y is CO or SO R R R R R R R R R Ar Het R R R R or C: wherein R is CHR R R R R R R R R R R R R Ar Het R R R R alk is an alkyl or alkylene radical; and wherein  the alkyl, alkylene and alkoxy radicals have straight or branched chains and comprise 1 to 6 carbon atoms, the cycloalkyl radicals comprise 3 to 10 carbon atoms and the heterocycloalkyl and heterocyclenyl radicals comprise 3 to 10 carbon atoms; or  an optical isomer thereof or a pharmaceutically acceptable salt thereof.