Patent ID: 8633197
Filing Date: 2014-01-21
Classification: A61P,C07D

Abstract:
1. A compound having the following formula including any stereochemically isomeric form thereof, wherein A represents N; X represents O or NR the dotted line represents an optional bond in case A represents a carbon atom; Y represents a direct bond; —NR Z represents a bivalent radical selected from C R R R R R R R R R R R aryl represents phenyl or phenyl substituted with at least one substituent, each substituent independently being selected from the group consisting of hydroxyl; carboxyl; halo; C aryl Het represents a monocyclic non-aromatic or aromatic heterocycle containing at least one heteroatom each independently selected from the group consisting of O, S, S(═O) Het p represents 1 or 2; a N-oxide thereof, a pharmaceutically acceptable salt thereof or a solvate thereof.