Patent ID: 7241880
Filing Date: 2007-07-10
Classification: C07K,C12Q,G01N,G16B

Abstract:
1. An isolated nucleic acid sequence which encodes a human hT1R2 taste receptor that specifically responds to sweet taste stimuli wherein said hT1R2 nucleic acid sequence is selected from the following: (i) a nucleic acid sequence which encodes the human T1R2 polypeptide comprising SEQ ID NO: 21; (ii) a nucleic acid sequence which encodes a polypeptide having at least 95% sequence identity to the human T1R2 polypeptide contained in SEQ ID NO: 21; (iii) a nucleic acid sequence which hybridizes to the human T1R2 encoding nucleic acid sequence contained in SEQ ID NO: 20 under stringent hybridization conditions which consist of hybridization in 50% formamide, 5×SSC and 1% SDS, incubating at 42° C., with wash in 0.2×SSC and 0.1% SDS at 65° C., wherein the hybridization and wash steps are each carried out for at least 1 minute; and (iv) the nucleic sequence contained in SEQ ID NO: 20 encoding a human T1R2 polypeptide.