Patent ID: 8812085
Filing Date: 2014-08-19
Classification: A61B,G01N

Abstract:
1. A medical diagnostic system enabling the detection of a second-harmonic-generation-forward/backward (SHG F/B) ratio from a subject, comprising: a beam scanning component; a subject plane imaging component optically coupled to the beam scanning component, wherein the subject plane imaging component is an epi-imaging system; an imaging component disposed in an optical path of the system to provide a conjugate image of the subject plane in an image plane; an image discriminating component disposed in the image plane; a first detector disposed in a first optical path from the image discriminating component to detect at least one of the direct backward-propagating SHG and the backscattered forward-propagating SHG; a second detector disposed in a second optical path from the image discriminating component to detect at least one of the other respective backscattered forward-propagating SHG and the direct backward-propagating SHG; and a processor to calculate the second-harmonic-generation-forward/backward ratio, from the data received by the two detectors.