Patent ID: 6861221
Filing Date: 2005-03-01
Classification: B01J,B82B,B82Y,C07B,C07H,C12Q,C40B,Y02A,Y10S

Abstract:
1. A method of nanofabrication comprising providing at least one type of linking oligonucleotide having a selected sequence, the sequence of each type of linking oligonucleotide having at least two portions; providing one or more types of nanoparticles having oligonucleotides attached thereto, the oligonucleotides on each of the types of nanoparticles having a sequence complementary to the sequence of a portion of a linking oligonucleotide and having a functional group that binds to the nanoparticles, wherein the oligonucleotides are attached to the nanoparticles in an aging process comprising contacting the oligonucleotides with the nanoparticles in aqueous solution for a period of time sufficient to allow some of the oligonucleotides to bind to the nanoparticles; and contacting the oligonucleotides and nanoparticles in an aqueous salt solution for an additional period of time sufficient to enable additional oligonucleotides to bind to the nanoparticles; and contacting the linking oligonucleotides and nanoparticles under conditions effective to allow hybridization of the oligonucleotides on the nanoparticles to the linking oligonucleotides so that a desired nanomaterial or nanostructure is formed wherein the nanoparticles are held together by the linking oligonucleotides.