Patent ID: 6740673
Filing Date: 2004-05-25
Classification: A61P,C07C,C07D

Abstract:
A compound of the following formula (I), or a solvate or pharmaceutically acceptable salt thereof: wherein Y and E are independently selected from a group represented by the following formula (II): wherein R, R1, R2 and R3 are independently selected from hydrogen, C1-C8 alkyl and C3-C8 alkoxyalkyl; m is 1; A is the ring system of formula (IX): where R12 is selected from bromine, chlorine, fluorine, carboxy, hydrogen, hydroxy, hydroxymethyl, trifluoromethyl, C2-C7 alkanoyloxy, C1-C6 alkyl, C1-C6 alkoxy, and C2-C7 alkoxycarbonyl, Z is N and X is a direct bond to Z; An is the acid addition salt of a pharmaceutically acceptable acid or the anion from a pharmaceutically acceptable salt, and isolated enantiomeric, diastereomeric and geometric isomers thereof, and mixtures thereof.