Patent ID: 6861524
Filing Date: 2005-03-01
Classification: A61P,C07D

Abstract:
1. A compound according to the formula (I) wherein Z is selected from the group consisting of —S(O) wherein R or R wherein R1 is selected from the group consisting of: —C —C —(CH —(CH wherein each carbon of —(CH Q is O, S, or NR3, n is independently an integer 0-6, p is independently an integer 0 or 1, and W is independently selected from the group consisting of hydrogen, C where B is —O—, —S—, —NR6—, where each CH of the aromatic or heteroaromatic ring may be independently replaced by a nitrogen atom, and each carbon of the aromatic ring may be independently substituted with an X substituent; where each X substituent is independently selected from the group consisting of hydrogen, halogen, methylenedioxy, —C where each Y is independently selected from the group consisting of hydrogen and halogen; wherein each R3 is independently selected from the group consisting of hydrogen, and C where each R4 and R5 is independently selected from the group consisting of hydrogen, and C where —NR6— is selected from the group consisting of an unsubstituted N, an N substituted with -hydrogen, —(C where phenyl is substituted with one to five substituents independently selected from the group consisting of hydrogen, halogen, methylenedioxy, —C R2 is selected from the group consisting of cyclopentyl, cyclopentenyl, and isopropyl, or a pharmaceutically acceptable salt, optical isomer, solvate or hydrate thereof, and wherein the compound is selected from the group consisting of: a pharmaceutically acceptable salt, optical isomer, solvate or hydrate thereof.