Patent ID: 8114389
Filing Date: 2012-02-14
Classification: A61K,A61P,A61Q,B82Y

Abstract:
1. An oil-in-water nanoemulsion comprising: a network of oil globules with an average size of less than 150 nm comprising at least one oil, at least one amphiphilic lipid, and at least one nonionic polymer, wherein said at least one nonionic polymer is chosen from polyether-polyurethanes comprising in their chain at least one polyoxyethylenated hydrophilic block and at least one hydrophobic block chosen from aliphatic chains, cycloaliphatic chains, and aromatic chains, and at least one ionic amphiphilic lipid chosen from cationic amphiphilic lipids and anionic amphiphilic lipids chosen from: in which R, which may be identical or different in embodiments wherein more than one of said alkylsulfonic derivative is used, is chosen from C wherein the at least one cationic amphiphilic lipid chosen from: A) quaternary ammonium salts of formula (IV): in which: R X B) quaternary ammonium salts of imidazolinium of formula (V): in which: R R R R X C) diquaternary ammonium salts of formula (VI): in which: R R X D) quaternary ammonium salts comprising at least one ester function chosen from said quaternary ammonium salts of formula (VII): in which: wherein said network is formed by the interaction of said at least one hydrophobic block of the at least one nonionic polymer and said at least one oil, and wherein said nanoemulsion is more viscous than an oil-in-water nanoemulsion lacking such network, with the proviso that the oil-in-water nanoemulsion does not comprise aminosilicone.