Patent ID: 6447920
Filing Date: 2002-09-10
Classification: C08F,C08J,G02B,Y10T

Abstract:
A composite material comprising(a) an inorganic or organic bulk material having covalently bonded to its surface initiator moieties for radical polymerization; and (b) a hydrophilic surface coating obtainable by applying one or more different ethylenically unsaturated hydrophilic macromonomers to the bulk material surface provided with the initiator radicals and polymerizing said macromonomers, wherein the macromonomers according to (b) are each of formula whereinR1 is hydrogen, C1-C6-alkyl or a radical â€”COORâ€²; R, Râ€² and R1â€² are each independently of the other hydrogen or C1-C6-alkyl; A is a direct bond or is a radical of formula â€”C(O)â€”(A1)nâ€”Xâ€”â€ƒâ€ƒ(2a) orâ€”(A2)mâ€”NHâ€”C(O)â€”Xâ€”â€ƒâ€ƒ(2b) orâ€”(A2)mâ€”Xâ€”C(O)â€”â€ƒâ€ƒ(2c) orâ€”C(O)â€”NHâ€”C(O)â€”Xâ€”â€ƒâ€ƒ(2d) orâ€ƒâ€”C(O)â€”X1â€”(alk*)â€”Xâ€”C(O)â€”â€ƒâ€ƒ(2e),wherein A1 is â€”Oâ€”C2-C12-alkylene which is unsubstituted or substituted by hydroxy, or is â€”Oâ€”C2-C12-alkylene-NHâ€”C(O)â€” or â€”Oâ€”C2-C12-alkylene-Oâ€”C(O)â€”NHâ€”R11â€”NHâ€”C(O)â€”, wherein R11 is linear or branched C1-C18-alkylene or unsubstituted or C1-C4-alkyl- or C1-C4-alkoxy-substituted C6-C10-arylene, C7-C18-aralkylene, C6-C10-arylene-C1-C2-alkylene-C6-C10-arylene, C3-C8-cycloalkylene, C3-C8-cycloalkylene-C1-C6-alkylene, C3-C8-cycloalkylene-C1-C2-alkylene-C3-C8-cycloalkylene or C1-C6-alkylene-C3-C8-cycloalkylene-C1-C6-alkylene,A2 is C1-C8-alkylene; phenylene or benzylene, m and n are each independently of the other the number 0 or 1, X, X1 and Xâ€² are each independently of the other a bivalent group â€”Oâ€” or â€”NRâ€³, whereinRâ€³ is hydrogen or C1-C6-alkyl, (alk*) is C2-C12-alkylene; and (oligomer) denotes (i) the radical of a telomer of formula wherein (alk) is C2-C12-alkylene, Q is a monovalent group that is suitable to act as a polymerization chain-reaction terminator, p is an integer from 2 to 250 and q is an integer from 0 to 100, wherein the total of (p+q) is an integer from 2 to 250, and B and Bâ€² are each independently of the other a 1,2-ethylene radical derivable from a copolymerizable vinyl monomer by replacing the vinylic double bond by a single bond, at least one of the radicals B and Bâ€² being substituted by a hydrophilic substituent; or (ii) the radical of an oligomer of the formula wherein R28 is hydrogen or unsubstituted or hydroxy-substituted C1-C12-alkyl, u is an integer from 2 to 250 and Qâ€² is a radical of a polymerization initiator; or (iii) the radical of formula wherein R28, X and u are as defined above, or (iv) the radical of an oligomer of formula wherein R2 and R2â€² are each independently C1-C4-alkyl, Anâˆ’ is an anion, v is an integer from 2 to 250, and Qâ€³ is a monovalent group that is suitable to act as a polymerization chain-reaction terminator; or (v) the radical of an oligopeptide of formula â€”(CHR4â€”C(O)â€”NH)tâ€”CHR4â€”COOHâ€ƒâ€ƒ(3d) orâ€”CHR4â€”(NHâ€”C(O)â€”CHR4)tâ€”NH2â€ƒâ€ƒ(3dâ€²), wherein R4 is hydrogen or C1-C4-alkyl which is unsubstituted or substituted by hydroxy, carboxy, carbamoyl, amino, phenyl, o-, m- or phydroxyphenyl, imidazolyl, indolyl or a radical â€”NHâ€”C(&boxH;NH)â€”NH2 and t is an integer from 2 to 250, or the radical of an oligopeptide based on proline or hydroxyproline; subject to the provisos that in case of (oligomer) being a radical of formula (3a), A is not a direct bond; in case of (oligomer) being a radical of formula (3b), (3c) or (3d), A is a radical of formula (2a), (2b), or (2d) or the macromer is of formula (1â€²); in case of (oligomer) being a radical of formula (3bâ€²), A is a direct bond; in case of (oligomer) being a radical of formula (3dâ€²), A is a radical of formula (2c) or (2e).