Patent ID: 8283152
Filing Date: 2012-10-09
Classification: C12N,C12P

Abstract:
1. A strain of Escherichia coli , capable of producing O-acetyl homoserine in high yield, which overexpresses homoserine acetyl transferase, aspartokinase, homoserine dehydrogenase, phosphoenolpyruvate carboxylase, aspartate aminotransferase, and aspartate semi-aldehyde dehydrogenase, wherein aspartokinase and homoserine dehydrogenase, phosphoenolpyruvate carboxylase, aspartate aminotransferase, aspartate semi-aldehyde dehydrogenase, and homoserine acetyl transferase are encoded by respective genes thrA, ppc, aspC and asd from Escherichia coli and metX from Deinococcus radiodurans.