Patent ID: 6358965
Filing Date: 2002-03-19
Classification: A61K,A61P,C07D

Abstract:
A method for the treatment and/or prophylaxis of diseases which involve neuronal degeneration which comprises administering to a patient in need of such treatment an effective amount of a compound of formula (I) in whichR1 is halogen, a CF3, (C1-C4) alkyl or (C1-C4) alkoxy group; n is 0 or 1 R2 is hydrogen or a (C1-C4) alkyl group; R3 is hydrogen, (C1-C6) alkyl, (C1-C6) alkoxy; halogen, a CF3 group, hydroxy, a group selected from (C3-C7) cycloalkyl, phenyl, phenoxy, phenylmethyl or phenylethyl, said group being optionally mono- or polysubstituted on the phenyl group by halogen, CF3, (C1-C4) alkyl or (C1-C4) alkoxy; R4 and R5 is each independently hydrogen, (C1-C6) alkyl, (C1-C6) alkoxy, halogen, a CF3 group or hydroxy; as well as their salts and solvates and their quaternary ammonium salts.