Patent ID: 6660255
Filing Date: 2003-12-09
Classification: A61K,A61P

Abstract:
A method of inhibiting the replication of a pathogen by administering a transcription inhibiting amount of at least one polyamide compound having the formX1X2 . . . Xm-&ggr;-X(m+1) . . . X(2mâˆ’1)X2m-&bgr;-Dp wherein X1, X2, XmX(m+1), X(2mâˆ’1), and X2m are carboxamide residues forming carboxamide binding pairs Xt/X2m, X2/X(2mâˆ’1), Xm/X(m+1), and &ggr; is &ggr;-aminobutyric acid or 2,4-diaminobutyric acid, &bgr; is &bgr;-alanine, and Dp is dimethylaminopropylamide, where m is an integer having a value from 3 to 6.