Patent ID: 8277816
Filing Date: 2012-10-02
Classification: A61K,A61P,C07K,C12N,C12Y

Abstract:
1. An isolated antigen comprising a component of Bacillus anthracis virulence factor fused to a LicKM protein; wherein the virulence factor component comprises at least one domain having an amino acid sequence with at least 95% identity to a sequence selected from the group consisting of SEQ ID NO.: 4, SEQ ID NO: 6, SEQ ID NO: 15, amino acid residues 1-137 of SEQ ID NO.: 2, amino acid residues 251-263 of SEQ ID NO.: 2, amino acid residues 138-250 of SEQ ID NO.: 2, amino acid residues 264-283 of SEQ ID NO.: 2, amino acid residues 429-551 of SEQ ID NO.: 2, amino acid residues 306-385 of SEQ ID NO.: 2, amino acid residues 552-776 of SEQ ID NO.: 2, amino acid residues 1-250 of SEQ ID NO.: 1, amino acid residues 251-456 of SEQ ID NO.: 1, amino acid residues 477-595 of SEQ ID NO.: 1, and amino acid residues 608-735 of SEQ ID NO.: 1; and wherein the LicKM protein comprises an amino acid sequence with at least 95% identity to SEQ ID NO.: 8 or SEQ ID NO.: 10.