Patent ID: 8105791
Filing Date: 2012-01-31
Classification: C07K,C12N,G01N

Abstract:
1. A method for producing an isolated population of mammalian cells enriched for mesenchymal stem cells relative to a reference population, the method comprising the steps of a) providing at least a portion of a population of cells, or a portion of a reference population, comprising at least one mesenchymal stem cell and at least one cell other than a mesenchymal stem cell, b) introducing into the population of cells in a) above an antibody or fragment thereof identifying an integrin alpha 10 chain expressed on the cell surface of mesenchymal stem cells, c) selecting and isolating from the population of cells in b) above the mesenchymal stem cell(s) expressing integrin alpha 10 chain, thereby producing a population of cells enriched for mesenchymal stem cells.