Patent ID: 7303758
Filing Date: 2007-12-04
Classification: A61L,A61P

Abstract:
1. A medical device comprising: an implantable structure; a basecoat matrix, including a combination of rapamycin and mycophenolic acid, in therapeutic dosages, incorporated in a first polymeric material, the basecoat matrix being affixed to the surface of the implantable medical device; and a topcoat, including a second polymeric material, affixed to the basecoat matrix for controlling the elution rate of the rapamycin and mycophenolic acid, the first and second polymeric materials comprising immiscible polymers forming a chemical and physical barrier to the elution of the rapamycin and the mycophenolic acid, one of the immiscible polymers comprising a fluoropolymer and one of the immiscible polymers comprising an acrylic.