Patent ID: 8969400
Filing Date: 2015-03-03
Classification: A61K,A61P

Abstract:
1. A method of treatment or alleviation of a CNS disorder of a living animal body, including a human, which method comprises the step of administering to such a living animal body in need thereof, a therapeutically effective amount of a combination of (i) a slow-release formulation of 5-hydroxytryptophan or a pharmaceutically acceptable salt thereof wherein the 5-hydroxytryptophan or salt thereof is administered at a dosage of from 10 to 100 mg/kg/day, wherein the slow-release formulation of 5-hydroxytryptophan has a half-life of from 8 to 24 hours; and (ii) a selective serotonin reuptake inhibitor (SSRI) or a pharmaceutically acceptable salt thereof, wherein the CNS disorder is a disorder or condition selected from the group consisting of depressive disorders, bipolar disorders, anxiety disorders, obesity and pain.