Patent ID: 8112150
Filing Date: 2012-02-07
Classification: A61B,A61N

Abstract:
1. A method of optimizing one or more programmer settings of a cardiac pacemaker comprising the steps of: attending to a patient with a cardiac pacemaker having one or more programmable settings; measuring the electrical activity of a heart of the patient in the form of an electrocardiogram which plots a sensed voltage difference between electrodes placed noninvasively on the patient's skin as a function of time, for each pulse of the heart, the electrocardiogram being characterized in part by a Q-wave; simultaneously using a sensor to measure a peripheral pressure waveform of the patient as a function of time; for each respective pulse, determining from the electrocardiogram a Q-wave and defining a corresponding time as an initial impulse time (T for each respective pulse, determining the realization of systolic onset in the detected peripheral pressure waveform and defining the corresponding time as a peripherally measured systolic onset time (T using T presenting information related to the calculated surrogate pre-ejection interval SPET; and adjusting one or more of the programmable settings for the cardiac pacemaker in an effort to optimize the value of the calculated surrogate pre-ejection time interval SPET for the patient.