Patent ID: 7247440
Filing Date: 2007-07-24
Classification: C07K,G01N

Abstract:
1. A method of screening a compound or its salt that alters the binding property between (1) a receptor protein or its salt containing an amino acid sequences of SEQ ID NO: 129 and (2) a polypeptide which specifically binds to the receptor protein, or its amide or ester, or a salt thereof, which method comprises: (i) contacting the polypeptide or its amide or ester, or a salt thereof with the receptor protein or its salt, (ii) contacting the polypeptide or its amide or ester, or a salt thereof and a test compound with the receptor protein or its salt, and (iii) (a) a binding amount of the polypeptide, or its amide or ester, or a salt thereof to the receptor protein or its salt of the (i) and (ii), or (b) a cell-stimulating activity of the (i) and (ii) is assayed and compared.