Patent ID: 7109208
Filing Date: 2006-09-19
Classification: A61K,A61P,C07D

Abstract:
1. A method of promoting extension of axon of a retinal ganglion cell, which comprises administering an effective amount of a compound having Rho kinase inhibitory activity to a patient wherein the compound having Rho kinase inhibitory activity is an amide compound represented by the formula (I) wherein Ra is a group of the formula  in the formula (b), R is hydrogen, alkyl, or cycloalkyl, cycloalkylalkyl, phenyl or aralkyl, which optionally has a substituent on the ring, or a group of the formula  wherein R R R and R R A is a group of the formula  wherein R Rb is a hydrogen, an alkyl, an aralkyl, an aminoalkyl or a mono- or dialkylaminoalkyl; and Rc is an optionally substituted 6-membered ring containing one nitrogen atom,