Patent ID: 9155698
Filing Date: 2015-10-13
Classification: A61K

Abstract:
1. A method of delivering a medicant in the oral cavity of a mammal, comprising disposing within the oral cavity of the mammal a thin film composition comprising the medicant, the thin film composition being prepared by a method comprising the steps of: providing a film layer comprising a water-soluble polymer selected from the group consisting of pullulan, modified starch, pectin, carrageenan, a maltrodextrin, and an alginate; or any combination thereof; applying a coating to said film layer without use of a solvent, wherein said coating comprises a powder matrix; wherein the powder matrix, prior to application to the film layer, is admixed in a fluidized bed that minimizes the generation of shear and heat; wherein the powder matrix comprises a medicant; the powder matrix further comprising a composition that, when placed in the oral cavity in contact with the mucosa therein, cases the thin film composition to adhere to the mucosa.