Patent ID: 7659277
Filing Date: 2010-02-09
Classification: A61K,A61P

Abstract:
1. A pharmaceutical composition, comprising a small molecule inhibitor of a POSH (Plenty of SH3 domains) polypeptide and at least one physiologically acceptable carrier or excipient, wherein the POSH polypeptide small molecule inhibitor is a compound having a structure of formula X and Y are independently selected from O, S, and NR R R R R represents, independently for each occurrence, H, alkyl, alkenyl, alkynyl, aralkyl, aryl, cycloalkyl, heterocyclyl, cycloalkylalkyl, heterocyclylalkyl, heteroaryl, or heteroaralkyl; and R provided that the POSH polypeptide small molecule inhibitor is not a compound having the structure