Patent ID: 8945907
Filing Date: 2015-02-03
Classification: C12N,C12P

Abstract:
1. A recombinant E. coli strain having L-tryptophan productivity derived from a mutant E. coli (KFCC 10066) having L-phenylalanine productivity, wherein tryptophan biosynthetic genes trpA-E are overexpressed at an expression level greater than or equal to a minimum expression level necessary for growth in a tryptophan free medium, and pheA, trpR, mtr and tnaAB genes are inactivated and aroG and trpE genes are mutated on the chromosome of said mutant E. coli such that the 449 th nucleotide of the aroG gene is substituted with thymine and the 61 st nucleotide of the trpE gene is substituted with thymine.