Patent ID: 6587732
Filing Date: 2003-07-01
Classification: A61M,G01N,H05B

Abstract:
A heat treatment method for achieving viral inactivation in a blood product, said method comprising the steps offlowing a blood product at a selected flow rate along a length of small diameter tubing formed into a series of coils including a first coil, a second coil and a third coil; applying electromagnetic energy to said first coil to heat the blood product flowing therein from an initial temperature to a selected elevated temperature sufficient for viral inactivation; cooling the second coil to rapidly cool the blood product flowing therein; radiometrically monitoring the temperature of the blood product in said first and second coils to produce first and second temperature signals; controlling the flowing, applying and/or cooling steps in response to said first and second temperature signals to impart a selected time/temperature profile to the blood product flowing in the tubing and to deliver the blood product to the third coil at a selected temperature somewhat below body temperature; applying electromagnetic energy to the third coil and the blood product flowing therein; radiometrically monitoring the temperature of the blood product in the third coil and producing a third temperature signal in response thereto, and controlling the energy applied to the third coil in response to the third temperature signal so that the blood product flowing in the third coil is reheated to body temperature whereby the body temperature is approached from below.