Patent ID: 7264947
Filing Date: 2007-09-04
Classification: A61K,A61P,C07K

Abstract:
1. An isolated nucleic acid that encodes an ADNF III polypeptide, wherein said isolated nucleic acid specifically hybridizes, under stringent conditions, to an ADNF III nucleic acid comprising a nucleic acid sequence complementary to SEQ ID NO:2, SEQ ID NO:56, or SEQ ID NO:58, wherein the stringent hybridization is carried out at 65° C. in a buffer comprising 5×SSC and 1% SDS or at 42° C. in a buffer comprising 50% formamide, 5×SSC, and 1% SDS; followed by a wash at 65° C. in a buffer comprising 0.2×SSC and 0.1% SDS, and wherein the encoded ADNF III polypeptide exhibits neuroprotective action on a neuron.