Patent ID: 6362880
Filing Date: 2002-03-26
Classification: G01N

Abstract:
A method for quickly converting from a single-flow configuration to a split-flow configuration of evaporative light scattering detection thereby providing increased ability to detect different sample types in different mobile phases, the method comprising:providing an evaporative light scattering detection device in the single-flow configuration comprising a nebulizer in fluid communication with one end of a drift tube, a light source and a detector; and converting to a split-flow configuration by removing the nebulizer and connecting a low temperature adaptor such that the low temperature adaptor is in fluid communication with the drift tube, the low temperature adapter comprising a low temperature adapter nebulizer, a nebulization chamber in fluid communication with the low temperature adapter nebulizer and the drift tube, wherein in the nebulization chamber at least a portion of a mobile phase carrying sample components is evaporated and a portion of the mobile phase is not evaporated, the nebulization chamber further comprising a sink trap in fluid communication with the nebulization chamber for removing mobile phase that is not evaporated in the nebulization chamber.