Patent ID: 7141072
Filing Date: 2006-11-28
Classification: A61B,A61F,A61L,Y10S

Abstract:
1. A method of promoting regeneration of surface cartilage of a joint, comprising: covering an area of damaged cartilage of a joint to be treated with a patch consisting essentially of a multi layer sheet of collagen membrane material, wherein said multi layer sheet of collagen membrane material is comprised of at least one barrier layer which acts as a barrier to inhibit passage of cells therethrough, wherein said at least one barrier layer has a thickness of about 0.2–2 mm and has a structure consisting essentially of collagen I, collagen III or mixtures thereof, wherein said sheet of collagen membrane material further comprises a matrix layer having a thickness of about 0.2–12 mm and having a matrix structure which consists essentially of collagen II having an open sponge like texture; wherein said barrier layer has at least one smooth face so as to inhibit cell adhesion thereon, said barrier layer further having a fibrous face opposite said smooth face, wherein said matrix layer is adhered to said fibrous face; fixing the patch over said area with the at least one said barrier layer oriented away from the damaged area, and said matrix layer with a matrix structure consisting essentially of collagen II oriented toward the damaged area wherein said patch is fixed over the damaged area without application of a separate hemostatic barrier layer in said area; and allowing said area to regenerate cartilage.