Patent ID: 6492330
Filing Date: 2002-12-10
Classification: A61K,A61P,C07K

Abstract:
An isolated peptide selected from the group consisting of:Aib-Met-Tyr-Pro-Thr-Tyr-Aib-Lys-OH(SEQ ID NO: 8)D-Leu-Met-Tyr-Pro-Thr-Tyr-Aib-Lys-OH(SEQ ID NO: 9)Leu-Met-Tyr-Pro-Thr-D-Tyr-Leu-Lys-OH(SEQ ID NO: 10)Leu-Met-Tyr-Pro-Thr-Tyr-D-Leu-Lys-OH(SEQ ID NO: 11)Leu-Met-D-Tyr-Pro-Thr-Tyr-D-Leu-Lys-OH(SEQ ID NO: 12)D-Leu-Met-Tyr-Pro-Thr-Tyr-D-Leu-Lys-OH(SEQ ID NO: 13)Aib-Met-Tyr-Pro-Thr-Tyr-Deg-Lys-OH(SEQ ID NO: 14)D-Leu-Met-Tyr-Pro-Thr-Tyr-Deg-Lys-OH(SEQ ID NO: 15)D-Phe-Gln-Trp-Aib-Val-Gly-His-Leu-NH2(SEQ ID NO: 16)D-Phe-Gln-Trp-Ala-Val-Aib-His-Leu-NH2(SEQ ID NO: 17)D-Phe-Gln-Trp-Aib-Val-Gly-His-Ile-NH2(SEQ ID NO: 18)D-Phe-Gln-Trp-Ala-Val-Aib-His-Ile-NH2(SEQ ID NO: 19)Aib-Met-Gln-Trp-Phe-Aib-NH2(SEQ ID NO: 20)D-Leu-Met-Gln-Trp-Phe-Aib-NH2(SEQ ID NO: 21)D-Arg-Pro-Lys-Pro-Aib-Gln-D-Trp-Phe-D-Trp-Aib-(SEQ ID NO: 22)Leu-NH2Ala-Aib-Cys-Lys-Asn-Phe-Phe-D-Trp-Lys-Thr-Phe-(SEQ ID NO: 23)Thr-Ser-Cys (3-14 Disulphide bond)Ala-Aib-Cys-Lys-Asn-Phe-Phe-D-Trp-Lys-Thr-Phe-(SEQ ID NO: 24)Thr-Ser-Cys andD-Phe-Cys-Tyr-D-Trp-Lys-Thr-Aib-Thr-NH2(SEQ ID NO: 25)wherein Aib=&agr;-Aminoisobutyric acid, Deg=&agr;, Diethyl glycine.