Patent ID: 7144883
Filing Date: 2006-12-05
Classification: A61K,A61P,C07D

Abstract:
1. A compound of the formula I or a pharmaceutically acceptable salt thereof, wherein: ring B is  in which D is a five-membered heterocyclic or heteroaryl ring, said ring comprising one or two atoms selected from the group consisting of nitrogen, sulfur and oxygen, with the proviso that when D contains an oxygen atom, D is heteroaryl; W is —(CH); P is P and R R (a) C (b) C (c) straight or branched C (d) straight or branched C (e) a group Ar; Ar is (a) phenyl, (b) 1-naphthyl, (c) 2-naphthyl, (d) benzyl, (e) cinnamoyl, (f) a 5 to 7-membered, optionally aromatic, partially saturated or completely saturated, heterocyclic ring containing 1 to 4 heteroatoms, selected from oxygen, nitrogen and sulfur, or (g) a bicyclic ring system comprising at least one heterocyclic ring according to (f); R (a) H, (b) C (c) C (d) straight or branched C (e) straight or branched C or R one of R X and Y are independently (a) H, (b) halogen, (c) C (d) —CF (e) hydroxy, (f) C (g) C (h) phenyl, (i) phenoxy, (j) benzyloxy, (k) benzoyl, (l) —OCF (m) —CN, (n) straight or branched C (o) straight or branched C (p) —NH (q) —NHR (r) —NR (s) —NO (t) —CONR (u) —NHSO (v) —NR (x) —SO (z) —C(═O)R (aa) —CO (ab) —S(O) (ac) —S—(C (ad) —SCF R (a) H, (b) C (c) C (d) Ar, as defined above for R alternatively, R R (a) H, or (b) straight of branched C