Patent ID: 7560286
Filing Date: 2009-07-14
Classification: C07C,Y10T

Abstract:
1. A method for structural analysis of at least one nitrogen-containing organic chain compound using a high-energy collision induced dissociation-mass/mass spectrometry (CID-MS/MS spectrometry), comprising the steps of: introducing a squaric acid residue into an N-terminal end of the at least one nitrogen-containing organic chain compound, where the squaric acid residue is represented by the chemical formula (I) inducing charge-remote fragmentation (CRF) using a high-energy collision induced dissociation-mass/mass spectrometry (CID-MS/MS spectrometry); and measuring one or more properties of the fragmented compound, and correlating the measurement to the structure of the at least one nitrogen-containing organic chain compound, wherein the nitrogen-containing organic chain compound is selected from the group consisting of peptides, peptide esters, polyamines, polyamine ethers, and organic chain compounds having amino groups on their ends.