Patent ID: 8653102
Filing Date: 2014-02-18
Classification: A61P,C07D

Abstract:
1. A substituted compound of general formula (I) wherein X denotes O or S, R a C R R R in which an “aliphatic group” and “aliphatic residue” can in each case be branched or unbranched, saturated or unsaturated, in which a “cycloaliphatic residue” and a “heterocycloaliphatic residue” can in each case be saturated or unsaturated, in which “mono- or polysubstituted” with respect to an “aliphatic group” and an “aliphatic residue” relates, with respect to the corresponding residues or groups, to the substitution of one or more hydrogen atoms each independently of one another by at least one substituent selected from the group consisting of F, Cl, Br, I, NO in which “mono- or polysubstituted” with respect to a “cycloaliphatic residue” and a “heterocycloaliphatic residue” relates, with respect to the corresponding residues, to the substitution of one or more hydrogen atoms each independently of one another by at least one substituent selected from the group consisting of F, Cl, Br, I, NO in which “mono- or polysubstituted” with respect to “aryl” and a “heteroaryl” relates, with respect to the corresponding residues, to the substitution of one or more hydrogen atoms each independently of one another by at least one substituent selected from the group consisting of F, Cl, Br, I, NO an NH(C 1-4 aliphatic residue), an N(C 1-4 aliphatic residue) 2 , an NH—C(═O)—C 1-4 aliphatic residue, an NH—S(═O) 2 —C 1-4 aliphatic residue, OH, OCF 3 , a O—C 1-4 -aliphatic residue, a O—C(═O)—C 1-4 -aliphatic residue, SH, SCF 3 , a S—C 1-4 -aliphatic residue, S(═O) 2 OH, a S(═O) 2 —C 1-4 -aliphatic residue, a S(═O) 2 —O—C 1-4 -aliphatic residue, a S(═O) 2 —NH—C 1-4 -aliphatic residue, CN, CF 3 , C(═O)H, C(═O)OH, a C 1-4 -aliphatic residue, a C(═O)—C 1-4 -aliphatic residue, a C(═O)—O—C 1-4 -aliphatic residue, a C 3-6 -cycloaliphatic residue, a 3 to 6 membered heterocycloaliphatic residue, benzyl, aryl, heteroaryl, C(═O)—NH 2 , a C(═O)—NH(C 1-4 aliphatic residue), and a C(═O)—N(C 1-4 aliphatic residue) 2 ; with the exception of the following compound: 1-ethyl-N-(4-methoxybenzyl)-4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxamide, in the form of the free compounds, the racemate, the enantiomers, diastereomers, mixtures of the enantiomers or diastereomers in any mixing ratio, or of an individual enantiomer or diastereomer, or in the form of the salts of physiologically acceptable acids or bases.