Patent ID: 6110913
Filing Date: 2000-08-29
Classification: A61P,C07D

Abstract:
A compound of formula I ##STR31## wherein R.sup.1 an R.sup.2 independently are hydrogen, halogen, trifluoromethyl, NR.sup.6 R.sup.7, hydroxy, C.sub.1-6 -alkyl or C.sub.1-6 -alkoxy wherein R.sup.6 and R.sup.7 independently are hydrogen or C.sub.1-6 -alkyl;Y is >N--CH.sub.2 --, wherein only the underscored atom participates in the ring system;X is --O--;r is 1, 2 or 3; andZ is selected from ##STR32## wherein R.sup.3 is --(CH.sub.2).sub.m OH or --(CH.sub.2).sub.p COR.sup.4 wherein m is 0, 1, 2, 3, 4, 5 or 6, p is 0 or 1 and R.sup.4 is --OH, --NH.sub.2, --NHOH or C.sub.1-6 -alkoxy; ora pharmaceutically acceptable salt thereof.