Patent ID: 7884075
Filing Date: 2011-02-08
Classification: A61K,A61P,C07K

Abstract:
1. A proteinaceous molecule comprising, (a) a VWF molecule selected from the group consisting of plasmatic von Willebrand factor (VWF), recombinant VWF, and dimers and multimers thereof; and (b) at least one physiologically acceptable polymer molecule bound to said VWF molecule; said proteinaceous molecule having the capability of binding at least one factor VIII (FVIII) molecule, wherein the in vivo half-life of said proteinaceous molecule is increased as compared to the in vivo half-life of a VWF molecule and the in vivo half-life of said FVIII molecule bound to said proteinaceous molecule is increased as compared to the in vivo half-life of a FVIII molecule not bound to said proteinaceous molecule.