Patent ID: 6017759
Filing Date: 2000-01-25
Classification: A61K,A61P,C07K,C12N

Abstract:
A chimeric cDNA which, when operably inserted as a heterologous DNA in a DNA of an expression host, encodes a chimeric polypeptide immunogen comprising the VP2 amino acid sequence of a first infectious bursal disease virus (IBDV) strain except for at least one amino acid X, wherein X is an epitopic determinant from a second IBDV strain wherein said IBDV strains are selected from the group consisting of GLS, E/Del, D78, DS326, RS593, Cu-1, PBG98, 52/70, STC and 002-73, and wherein said immunogen comprises the amino acid sequence, in order, for IBDV structural proteins VP2-VP4-VP3.