Patent ID: 6214996
Filing Date: 2001-04-10
Classification: A61P,C07D,C07F

Abstract:
A naphthalene derivative of the formula (I): ##STR172##wherein R.sup.1 and R.sup.2 are the same or different and are each a hydrogen atom or a protected or unprotected hydroxy group; either one of R.sup.3 and R.sup.4 is a protected or unprotected hydroxy-substituted methyl group, and another is a hydrogen atom, a lower alkyl group, or a protected or unprotected hydroxy-substituted methyl group; R.sup.5 and R.sup.6 are both bond at their termini and combine with the adjacent nitrogen atom to form a substituted or unsubstituted isoquinolyl group that may be partially or wholly hydrogenated or, a five membered heterocyclicring, or a pharmaceutically acceptable salt thereof, with the proviso that R.sup.5 and R.sup.6 do not combine with the adjacent nitrogen atom to form phtharazinyl or quinolyl.