Patent ID: 8658686
Filing Date: 2014-02-25
Classification: A61P,C07D

Abstract:
1. A pyrazole compound of formula (1), a tautomer of the compound, or a pharmaceutically acceptable salt or solvate thereof: wherein R when there are two neighboring R R when there are two neighboring R R X is a single bond or —(CR R R R when there are two neighboring R D1 to D23 are aromatic heterocyclic rings of structural formulae, respectively, E1 to E8 are saturated heterocyclic rings of structural formulae, respectively, M1 to M9 are partially unsaturated aromatic heterocyclic rings of formulae, respectively, F1 and F2 are rings of formulae, respectively, R R R when there are two neighboring R R R when there are two neighboring R R R R R R when there are two neighboring R R R R R R R R R Z is a halogen atom, cyano, nitro, C a, b, d, e, f, g, k and m are each independently an integer of from 1 to 5, c is an integer of from 0 to 2, q1 is an integer of from 0 to 3, q2 is an integer of from 0 to 5, q3 is an integer of from 0 to 7, q4 is an integer of from 0 to 6, q5 is an integer of from 0 to 4, r is an integer of from 0 to 2, s1 is an integer of from 0 to 4, s2 is an integer of from 0 to 3, s3 is an integer of from 0 to 2, s4 is an integer of 0 or 1, n is an integer of 1, t is an integer of 0 or 1, and u is an integer of 0 or 1.