Patent ID: 6299900
Filing Date: 2001-10-09
Classification: A61K,A61M,A61P,A61Q,Y02A,Y10S

Abstract:
A transdermal drug delivery system which comprises:a therapeutically effective amount of at least one physiologically active agent; andat least one dermal penetration enhancer present in an amount of from 10 to 10,000 wt % based on the weight of the active agent; wherein the dermal penetration enhancer is at least one ofa safe skin-tolerant ester sunscreen of formula (I): ##STR2##whereinR.sup.3 is hydrogen, lower alkyl, lower alkoxy, halide, hydroxy or NR.sup.3 R.sup.4 ;R.sup.2 is a C.sub.8 to C.sub.18 alkyl,R.sup.3 and R.sup.4 are each independently hydrogen, lower alkyl or R.sup.3 and R.sup.4 together with the nitrogen atom to which they are attached form a 5- or 6-membered heterocyclic ring;n is 0 or 1, andq is 1 or 2,wherein when n is 0 and R.sup.1 is NR.sup.3 R.sup.4, then NR.sup.3 R.sup.4 is para-substituted.