Patent ID: 6630191
Filing Date: 2003-10-07
Classification: A23L,C07K

Abstract:
A aspartyl dipeptide ester derivative and salts thereof represented by formula (1) wherein;R1, R2, R3, R4 and R5, independently from each other, each represents a substituent selected from the group consisting of a hydrogen atom, a hydroxyl group, an alkoxy group having from 1 to 3 carbon atoms, an alkyl group having from 1 to 3 carbon atoms and a hydroxyalkyloxy group having 2 or 3 carbon atoms; wherein, optionally, R1 and R2, or R2 and R3 together form a methylenedioxy group (OCH2O) wherein R4, R5, and R1 or R3 which does not form the methylenedioxy group, independently from each other, are defined as above; R6 is selected from the group consisting of a hydrogen atom, a benzyl group (CH2C6H5), a p-hydroxybenzyl group (CH2C6H4-p-OH), a cyclohexylmethyl group (CH2C6H11), a phenyl group (C6H5), a cyclohexyl group (C6H11), a phenylethyl group (CH2CH2C6H5) and a cyclohexylethyl group (CH2CH2C6H11); R7 is selected from a hydrogen atom, a methyl group (CH3), an ethyl group (CH2CH3) and an isopropyl group (CH (CH3)2); R8 represents a substituent selected from a methyl group, an ethyl group, an isopropyl group, a n-propyl group (CH2CH2CH3) and a t-butyl group (C(CH3)3); provided the derivatives in which R6 represents a benzyl group and R7 represents a hydrogen atom at the same time, and the derivatives in which R6 represents a p-hydroxybenzyl group and R7 represents a hydrogen atom at the same time are excluded.