Patent ID: 8803106
Filing Date: 2014-08-12
Classification: G01N,G02B

Abstract:
1. An optical analysis device which detects and analyzes light from a light-emitting particle dispersed and moving at random in a sample solution using an optical system of a confocal microscope or a multiphoton microscope, comprising: a light detection region moving portion which moves a position of a light detection region of the optical system in the sample solution by changing an optical path of the optical system; a light irradiating portion which irradiates the light detection region with excitation light including a predetermined polarized light component; a light detecting portion which detects an intensity of at least one polarized light component of light from the light detection region; and a signal processing portion which generates a time series light intensity data of the at least one polarized light component of the light from the light detection region detected by the light detecting portion while moving the position of the light detection region in the sample solution, detects individually a signal from each light-emitting particle in the intensity of the at least one polarized light component of the light detected with the light detection portion with moving the position of the light detection region in the sample solution by detecting individually in the time series light intensity data, as the signal of one light-emitting particle, a variation in time of a light intensity having a profile expected in the light from one light-emitting particle which moves relatively in an inside of the light detection region, and computes, based on the intensity of the at least one polarized light component of the signal of the light of the detected light-emitting particle, a polarization characteristic value of the light-emitting particle.