Patent ID: 8450356
Filing Date: 2013-05-28
Classification: A61K,A61P

Abstract:
1. A method of producing a radiation sensitizer composition having enhanced storage stability consisting essentially of a radiation sensitizer compound and a compound having chelating ability, wherein the method comprises: combining a 1-(1-hydroxymethyl-2,3-dihydroxypropyloxymethyl)-2-nitroimidazole radiation sensitizer compound represented by formula (1): and a compound having chelating ability selected from the group consisting of a saccharic acid, a salt of a saccharic acid, an aminopolycarboxylic acid, a salt of an aminopolycarboxylic acid, an oxycarboxylic acid, a salt of an oxycarboxylic acid, an amine compound, a polyoxyethylene castor oil, and mixtures thereof.