Patent ID: 8492345
Filing Date: 2013-07-23
Classification: A61K,A61P,C07K

Abstract:
1. A method of inhibiting cancer cell proliferation, said method comprising: providing a compound of formula wherein each of R 1 -R 5 is independently selected from H and alkyl moieties; X 1 is selected from O and NR 4 ; R 1 ′ is X 2 ArCH 2 —, wherein X 2 is selected from Br, Cl and alkyl, and Ar is selected from aryl and heteroaromatic moieties; and each of R 2 ′-R 5 ′ is independently selected from R 1 ′, CH 3 —, (CH 3 ) 2 CH—, (CH 3 ) 2 CHCH 2 —, CH 3 CH 2 (CH 3 )CH— and CH 3 S CH 2 CH 2 — moieties; and contacting cancer cells with said compound, said cells selected from prostate, breast, pancreatic, and melanoma cancer cells.