Patent ID: 8372647
Filing Date: 2013-02-12
Classification: G01N,Y10T

Abstract:
1. A method for determining if a subject has pancreatic cancer, sequentially comprising the following steps (1) to (4): (1) a step of releasing N-linked sugar chains from glycoprotein in blood collected from a test subject; (2) a step of purifying the released sugar chains; (3) a step of performing mass spectrometry on the purified sugar chains; and (4) a step of determining if the subject has the pancreatic cancer using as an index a significant decrease of detected intensity of sugar chains having a peak mass/charge ratio (m/z) of 3031 and 2362 in mass spectrometry using a MALDI-TOF-MS analyzer, compared to that of a patient with pancreaticobiliary-duct benign disorder; wherein the peak mass/charge ratio (m/z) in the mass spectrometry is a level obtained when capturing and labeling the released sugar chains using beads for capturing sugar chains.