Patent ID: 7078465
Filing Date: 2006-07-18
Classification: C07B,C07C,C07F

Abstract:
1. A process for bromomethylation of organic compounds, wherein said process is a two stage process comprising of the following steps: (a) reacting paraformaldehyde with hydrogen bromide under aqueous conditions for 0.5 to 1.5 hours at a temperature between −0° C. and 20° C., and separating bis-bromomethyl ether (BBME) from the reaction mixture, and, (b) reacting BBME obtained in stage (a) with an organic compound selected from the group consisting of substituted or non-substituted phenyl, biphenyl, styryl, naphthyl, pyridyl, thiophene, 5 and 6 member heterocycles, polystyrenes and divinylbenzene-styrene copolymers, in the presence of a Lewis acid selected from the group consisting of zinc bromide, SnBr