Patent ID: 8592372
Filing Date: 2013-11-26
Classification: A61K,A61P

Abstract:
1. A method of improving liver function comprising: administering to a subject in need thereof prior to, during and after a liver surgery a high dose of insulin and a dose of dextrose sufficient to avoid hypoglycemia for a time sufficient for improving organ function, wherein a starting blood glucose level of said subject prior to said administering is from about 4 mmol/L to about 6 mmol/L, wherein said administering is for maintaining a target blood glucose level of said subject from about 3.5 mmol/L to less than about 8.5 mmol/L, wherein said method is for the treatment of a liver requiring surgical resection, a resected liver, a liver transplant, or a liver condition caused by a cancer, and wherein a rate of administration of said high dose of insulin is from about 1 mU/kg/min to about 5 mU/kg/min.