Patent ID: 6309723
Filing Date: 2001-10-30
Classification: A61J,A61L,C08L,G02B,Y10T

Abstract:
A protein-compatible film product made from a polymer blend, said product being made by the extrusion shearing of said polymer blend, said polymer blend comprising:a. a water-soluble polymer selected from the group consisting of poly(ethylene oxide), poly(vinyl alcohol), poly(ethyl oxazoline), poly(acryl amide), and poly(vinyl pyrrolidone); and,b. a matrix polymer selected from the group consisting of ethylene vinyl acetate copolymers, polyolefins, polyvinylchloride, polystyrene polymers and copolymers of polystyrenes, polycarbonate, polyacrylates, polyamide polymers and copolymers of polyamides, and polyester polymers and copolymers of polyesters;wherein the glass transition temperature of at least one of said water-soluble polymer or matrix polymer is greater than the application temperature, which is the highest temperature at which the product will be exposed during distribution, storage, or usage, and while in contact with a protein-containing solution; andwherein protein adsorption of the film product is reduced in an amount within the range of from about 16% to about 92% as compared to a protein adsorption of a corresponding second product comprising 100% by weight of the same matrix polymer.