Patent ID: 7012074
Filing Date: 2006-03-14
Classification: A61K,A61P,C07D

Abstract:
1. A method for the treatment or prophylaxis of an atrial arrhythmia comprising administering to a patient in need thereof an effective amount of a compound of formula I: wherein one of R R R R R R R R R R D represents a direct bond or C R R R R R R R R E represents, at each occurrence when used herein, a direct bond or C p represents 1 or 2; A represents -G-, -J-N(R B represents -Z-, -Z-N(R G represents C J represents C Z represents a direct bond or C R R Het Het R R n represents, at each occurrence, 0, 1 or 2; and R wherein each aryl and aryloxy group, unless otherwise specified, is optionally substituted by one or more of substituents including —OH, cyano, halo, nitro, C or a quaternary ammonium salt, an N-oxide, a pharmaceutically acceptable salt, a diastereomer or a tautomer thereof.