Patent ID: 8101274
Filing Date: 2012-01-24
Classification: A61L,A61P,C08L,G01N,Y10T

Abstract:
1. A method of extracting target molecules from a sample comprising the step of: (a) providing a dryable solid state film having at least one functionally active surface with binding affinity for a target molecule, said film comprising a non-polar solid substrate having upper and lower surfaces, said substrate having directly affixed thereto a plurality of glycosylated amphiphilic molecules in a stable amphiphilic alignment, each of which comprise a hydrophobic tail end and a hydrophilic head end provided with one or more functional groups, wherein the hydrophobic tail ends are embedded in or chemically linked to the upper surface of said non-polar solid substrate and the functional groups of the hydrophilic tail ends have binding affinity for a target molecule and project from said upper surface so as to provide at least one surface of said film with binding activity; (b) exposing said sample to the solid state film of part (a), wherein the functional groups present at the hydrophilic tail end of the glycosylated amphiphilic molecules have a binding affinity for a target molecule; (c) allowing sufficient time for said functional groups to bind target molecules present in said sample; and (d) removing or separating said film, to which said target molecules are bound, from said sample.