Patent ID: 7811993
Filing Date: 2010-10-12
Classification: A61K,A61P,C07K

Abstract:
1. A compound of the formula R1-Leu-AA2-AA3-Glu-AA5-AA6-AA7-Trp-AA 9-AA10-R2 (SEQ ID NO: 4), or a pharmaceutically acceptable salt thereof, wherein AA2 is an amino acid selected from the group consisting of a substituted or unsubstituted Ala, Leu, Met, Val, Pro and Gly; wherein AA3 is an amino acid selected from the group consisting of a substituted or unsubstituted Thr and Ser; wherein AA5 is an amino acid selected from the group consisting of a substituted or unsubstituted Lys, Arg and His; wherein AA6 is an amino acid selected from the group consisting of a substituted or unsubstituted Ser and Thr; wherein AA7 is an amino acid selected from the group consisting of a substituted or unsubstituted Arg, Lys, and His; wherein AA9 is an amino acid selected from the group consisting of a substituted or unsubstituted Thr, Val, Leu and Ser; wherein AA10 is absent or is a substituted or unsubstituted Gly, Pro or Leu; wherein R1 is absent or a Cys for coupling to a second peptide or protein; and wherein R2 is absent or a Cys for coupling to a second peptide or protein.