Patent ID: 7629472
Filing Date: 2009-12-08
Classification: C07D

Abstract:
1. A method for producing an optically active β-hydroxy ester compound represented by the general formula: wherein R R wherein the ring may be substituted, and may have one or more heteroatoms selected from the group consisting of an oxygen atom, a sulfur atom and a nitrogen atom in addition to the nitrogen atom in the formula, and may have one or more double bonds in addition to the double bond in the formula; or the general formula: wherein the ring may be substituted, and may have one or more heteroatoms selected from the group consisting of an oxygen atom, a sulfur atom and a nitrogen atom in addition to the nitrogen atom in the formula, and may have one or more double bonds in addition to the double bond in the formula, R R the symbol “*” represents an optically active center, or a salt thereof, which comprises reacting, in the presence of a cinchona alkaloid selected from the group consisting of cinchonine, cinchonidine, quinine and quinidine or a salt thereof, a compound represented by the general formula: wherein R 1 and R 2 are as defined above or a salt thereof with a compound represented by the general formula: wherein R 3 , R 4 and R 5 are as defined above, and X is a halogen atom, or a polymer thereof or a salt thereof.