Patent ID: 6107330
Filing Date: 2000-08-22
Classification: A61K,A61P,C07D

Abstract:
A method of at least one of inhibiting development of dependency induced by a narcotic analgesic agent and inhibiting development of tolerance to analgesic action induced by a narcotic analgesic agent, comprising:administering a narcotic analgesic agent;administering at least one of a therapeutically effective amount and a preventively effective amount of a medicament to at least one of inhibit development of dependency induced by the narcotic analgesic agent and inhibit development of tolerance to analgesic action induced by the narcotic analgesic agent; andwherein the medicament comprises an active ingredient represented by the following formula: R.sup.2 -CH.sub.2 CONH-R.sup.1 wherein R.sup.1 represents a pyridyl group, a substituted pyridyl group, phenyl group, or a substituted phenyl group; and R.sup.2 represents 2-oxo-1-pyrrolidinyl group which may optionally be substituted.