Patent ID: 6184380
Filing Date: 2001-02-06
Classification: C07D

Abstract:
A process for preparing a compound of the formula ##STR13##whereinR.sup.1 is benzyl, wherein the phenyl of the benzyl may be substituted by one or more of C.sub.1 --C.sub.6 alkyl, C.sub.1 --C.sub.6 alkoxy, halo, nitro, amino or trifluoromethyl, andR.sup.2 is C.sub.1 --C.sub.6 alkyl, trifluoromethyl, or phenyl which may be substituted by one or more of C.sub.1 --C.sub.6 alkyl, C.sub.1 --C.sub.6 alkoxy, halo, nitro, amino or trifluoromethyl, which comprises(a) reducing a compound of the formula ##STR14##wherein R.sup.1 is as defined above, in the presence of iron and a organic solvent under acidic conditions, and(b) acylating the compound of formula III formed: ##STR15##with an acylating agent of the formula R.sup.2 C(O)X wherein R.sup.2 is as defined above, and X is a leaving group.