Patent ID: 8778923
Filing Date: 2014-07-15
Classification: A61K,A61P,C07D,C07K

Abstract:
1. A compound having the structure of Formula I-R or I-S or a pharmaceutically acceptable isomer, enantiomer, racemate, salt, ester, prodrug, hydrate or solvate thereof: wherein A is a 5-, 6- or 7-membered heteroaryl having one, two or three heteroatoms where each such heteroatom is independently selected from O, N, and S, and where any ring atom of such heteroaryl may be optionally substituted with one or more of R B is heterocyclyl or heterocyclylalkyl; C is aryl or arylalkyl; Y Z is —C(O)—; each R R each R each R each R each R W each L each R R R R each R L each L each m is independently 0, 1, 2, 3, 4, 5 or 6; each n is independently 0 or 1 or 2; p is 0, 1, 2 or 3; q is 0, 1, 2 or 3; each r is independently 2, 3, or 4; and each s is independently 1, 2, 3, or 4.