Patent ID: 7510734
Filing Date: 2009-03-31
Classification: A61K,A61P,A61Q

Abstract:
1. A method of stimulating beta-defensins in skin cells which comprises applying to the skin cells an effective amount of a Lactobacillus plantarum extract or active fraction thereof selected from the group consisting of: (a) a heat exchange-treated Lactobacillus plantarum ferment comprising broken up cells of Lactobacillus plantarum ; (b) a filtrate fraction of a heat exchange-treated Lactobacillus plantarum ferment, wherein said filtrate fraction comprises water soluble cellular debris of Lactobacillus plantarum ; (c) a retentate fraction of a heat exchange-treated Lactobacillus plantarum ferment, wherein said retentate fraction comprises water-insoluble cellular debris of Lactobacillus plantarum ; and (d) one or more combinations of said extracts or fractions.