Patent ID: 6458948
Filing Date: 2002-10-01
Classification: C07C,C07D,C07K

Abstract:
A method of preparing a carboxylic acid derivative comprising mixing a quaternary ammonium salt represented by the following general formula (I), a carboxylic acid compound and a compound having a nucleophilic functional group, to condense the carboxylic acid with the compound having the nucleophilic function group, wherein the condensation is carried out in water, in a protonic organic solvent or in an organic solvent containing water, whereinE is a monovalent or divalent organic group having one or two tertiary amino groups, said organic group being appended to the triazine ring through the nitrogen atom of said tertiary amino group; n is 1 when E has one tertiary amino group, and is 2 when E has two tertiary amino groups, R1 and R2 are, independently from each other, alkyl groups having 1 to 4 carbon atoms or aryl groups having 6 to 8 carbon atoms; a is 1 or 2, and is 1 when n is 1; and Zâˆ’(n/a) is a counter anion having a valency of (n/a).