Patent ID: 6335205
Filing Date: 2002-01-01
Classification: G01N,Y10S

Abstract:
A chromatographic test strip for determining an analyte in an analyte solution, comprisingat least one absorbent matrix located on a carrier material and defining a plurality of zones each in liquid-transferring contact with the adjacent zone(s), the plurality of zones having an application zone at one end and a suction zone at the other end, a conjugate zone located in the application zone or adjoining the application zone and containing a visually detectable, particle-labelled analyte binding partner, a chromatographic zone adjoining the conjugate zone, a capture zone located between the chromatographic zone and the suction zone and containing solid phase-bound binding partners for the analyte or for an unlabelled analyte-specific binding partner, and a fluorescent dye located in the application zone or in a zone between the application zone and the capture zone and formed to migrate chromatographically in the analyte solution at least partly through the capture zone and to provide fluorescence contrast amplification of the particle label when the particle label is bound in the capture zone.