Patent ID: 9097719
Filing Date: 2015-08-04
Classification: B01L,B82Y,C12Q,G01N,Y10S

Abstract:
1. A DNA sequencing system comprising: a moving part formed on a moving part substrate configured to operate at room temperature and having a hole or a channel, wherein the hole or channel has a size through which one strand of a predetermined DNA double helix can move and a conductive thin film in the substrate for reacting to the nearest nucleotide; a sensing part formed on a separate sensing part substrate configured to operate at low temperatures for improving charge sensitivity and operating characteristics of the sensing part and comprising a single-electron transistor capable of measuring a conductivity variation of the single-electron transistor based on the charge distribution of the conductive thin film, said charge distribution varying according to electrical reaction between the conductive thin film and the nearest nucleotide; wherein the single-electron transistor comprises: an extended gate comprising a metal wire to couple the conductive thin film in the moving part to the second gate in the sensing part, wherein the extended gate reduces thermal conductivity between the substrates and increases signal transfer characteristics between the substrates.