Patent ID: 6153642
Filing Date: 2000-11-28
Classification: A61P,C07D

Abstract:
A compound which is a benzoheterocyclic distamycin derivative of formula: ##STR19## wherein: n is 2, 3 or 4;A is NR, wherein R is hydrogen or C.sub.1 -C.sub.4 alkyl;B is CH;R.sub.1 is hydrogen or C.sub.1 -C.sub.4 alkyl;T is selected from: ##STR20## wherein: p is zero or 1; R.sub.2 and R.sub.3 are selected, each independently, from: hydrogen, C.sub.1 -C.sub.4 alkyl optionally substituted by one or more fluorine atoms, and C.sub.1 -C.sub.4 alkoxy; R.sub.4 is C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.3 haloalkyl; X.sub.1 is a halogen atom; and ##STR21## wherein X.sub.2 is a halogen atom; or a pharmaceutically acceptable salt thereof.