Patent ID: 7049348
Filing Date: 2006-05-23
Classification: A61L

Abstract:
1. A porous polymeric device, said device being implantable to treat tissue or defects therein; said device comprising a polymer matrix, pores, and at least one modeling agent; wherein said device comprises a plurality of internal surfaces that define a plurality of said pores, wherein at least said pores are arranged substantially homogeneously throughout said device, wherein said pores are of irregular shapes due to interactions with said at least one pore modeling agent during processing, and further wherein substantially each of said internal surfaces has expanded at least partially around an external surface of at least one modeling agent, thereby imparting an inward-directed textured or roughened face to said internal surfaces, and wherein said modeling agent is at least partially exposed to said pores, and further wherein said modeling agent comprises chitosan and sodium hyaluronate that can chemically react with each other upon exposure of said pores to a fluid.