Patent ID: 7238701
Filing Date: 2007-07-03
Classification: A61P,C07D

Abstract:
1. A compound of formula wherein R is in each instance selected independently from H, (C  or R is (C R R R R R R R  NH(C R  NHC(O)NR R R R R Z is selected from CH Z or a pharmaceutically acceptable salt or ester thereof, excluding the following compounds: 5,6,7,8-tetrahydro-7-methyl-N-[4-(phenylmethoxy)phenyl]-[1]benzothieno-[2,3-d]pyrimidin-4-amine, monohydrochloride; 5,6,7,8-tetrahydro-N-(4-methoxyphenyl)-7-methyl-[1]benzothieno[2,3-]pyrimidin-4-amine, monohydrochloride; 5,6,7,8-tetrahydro-7-methyl-N-[3-(trifluoromethyl)phenyl]-[1]benzothieno-[2,3-d]pyrimidin-4-amine; N-(3,4-dimethylphenyl)-5,6,7,8-tetrahydro-7-methyl [1]benzothieno-[2,3-d]pyrimidin-4-amine.