Patent ID: 8238993
Filing Date: 2012-08-07
Classification: A61B,G01N

Abstract:
1. An apparatus for the determination of a tissue state in an individual, where “tissue state” is any of (i) a disease state based on long-term changes (greater than one month duration) in tissue, (ii) a measure of chemical change based on long-term (greater than one month duration) glycemic control, (iii) a measure of glycation end-products in tissue, and (iv) a combination of the above, comprising: (a) an illumination subsystem; (b) a detection subsystem; and (c) an input system, configured to accept biologic information comprising one or more of: gender of the individual, weight of the individual, waist circumference of the individual, history of disease of the individual's family, ethnicity, skin melanin content, smoking history of the individual, or a combination thereof; (d) an analysis subsystem, comprising a model relating fluorescence lifetime of the skin of an individual and the biologic information to tissue state.