Patent ID: 6337074
Filing Date: 2002-01-08
Classification: A61K,C07K,C12N

Abstract:
An antiviral agent which prevents or hinders replication of a herpesvirus in vitro by specifically binding to POL or UL8, thus inhibiting the association between UL8 and POL, wherein â€œUL8â€  is defined as UL8 of HSV-1 or the homologues thereof in other herpesviruses and â€œPOLâ€  is defined as POL of HSV-1 or homologues thereof in other herpesviruses, wherein said agent is a peptide selected from the group of peptides:a) VFTGVLAGVWGEGGKFVYPFDDKMSFLFA (SEQ ID NO: 5); b) IELVFTGVLAGVWGEGGKFV (SEQ ID NO: 7); c) DEWVRSLAVDAQHASKRVASEGLRFFRLNA (SEQ ID NO: 11) and; TWLEERDEWVRSLAVDAQHAARRVAS (SEQ ID NO: 12).