Patent ID: 8404434
Filing Date: 2013-03-26
Classification: G01N,Y10T

Abstract:
1. A method for determining if environmental and metabolic conditions of macrophages within the living body of a patient are either in hypoxic conditions or under conditions in which glucose is depleted, and therefore angiogenesis is promoted and cancer is recurring, or infiltration or activation of cancer cells has occurred, comprising: measuring the level of diacetylpolyamine contained in a macrophage sample collected from the patient to obtain a sample diacetylpolyamine level, measuring the levels of diacetylpolyamine contained in macrophage samples from healthy subjects to obtain a mean value and reference diacetylpolyamine level, comparing the sample diacetylpolyamine level with the reference diacetylpolyamine level, and when the sample diacetylpolyamine level is higher than the reference diacetylpolyamine level the environmental and metabolic conditions of macrophages within the living body of the patient are either in hypoxic conditions or under conditions in which glucose is depleted, and angiogenesis is promoted and cancer is recurring, or infiltration or activation of cancer cells has occurred.