Patent ID: 6610828
Filing Date: 2003-08-26
Classification: C07K,C12N

Abstract:
An isolated polypeptide comprising a polypeptide selected from the group consisting of:(a) the Heliothis virescens ecdysone steroid receptor shown in SEQ ID NO:5; (b) the transactivation domain of the Heliothis virescens ecdysone steroid receptor shown in amino acids 1-162 of SEQ ID NO:5; (c) the DNA binding domain of the Heliothis virescens ecdysone steroid receptor shown in amino acids 163-228 of SEQ ID NO:5; (d) the, hinge domain of the Heliothis virescens ecdysone steroid receptor shown in amino acids 229-326 of SEQ ID NO:5; (e) the ligand binding domain of the Heliothis virescens ecdysone receptor shown in amino acids 327-545 of SEQ ID NO:5; and (f) a derivative of the polypeptide of (a), (b), (d) or (e), wherein the derivative comprises one or more conservatively substituted amino acids and the derivative retains the function of the polypeptide, wherein the function is selected from the group consisting of ecdysone steroid receptor activity, ecdysone steroid receptor transactivation activity, ecdysone steroid receptor hinge domain activity, and ecdysone receptor ligand binding activity.