Patent ID: 8076372
Filing Date: 2011-12-13
Classification: A61P,C07C,C07D

Abstract:
1. A method of treating a retroviral infection in an infected mammal, the method comprising administering a compound of formula (I) or a pharmaceutical formulation comprising a compound of formula (I): wherein K is selected from the group consisting of K wherein A, B, D, and E are each independently selected from the group consisting of CH, CR J′ and Q′ designate the attachment points for groups J and Q respectively; R J is a member selected from the group consisting of (CH where m is an integer from 0 to 2; Z is a member selected from the group consisting of O, S, and NR Y is a member selected from the group consisting of a bond, O, S, and NR T is an optionally substituted alkylene of up to about 4 carbons; R R R Q is a member selected from the group consisting of a bond, optionally substituted alkylene, optionally substituted alkylene-C(O), optionally substituted phenylene, optionally substituted cycloalkylene, optionally substituted alkylcycloalkylene, optionally substituted cycloalkylenealkyl, wherein L R R R wherein the retroviral infection is due to a retrovirus selected from the group consisting of an HIV-1, an HIV-2, an SIV, a BIV, an EIAV, a Visna, a CaEV, an HTLV-1, a BLV, an MPMV, an MMTV, an RSV, an MuLV, a FeLV, a BaEV and an SSV retrovirus.