Patent ID: 7381730
Filing Date: 2008-06-03
Classification: C07D

Abstract:
1. A compound of the formula I wherein X is O; A and B are each independently CR′″ or N, wherein A and B are each CR′″, or one of A and B is CR′″ and the of A and B is N; R is H; R′ is H; R R″ is selected from the group consisting of hydrogen, alkyl, benzyl, p-methoxybenzyl, allyl and Si(R R′″ is selected from the group consisting of hydrogen, halogen, CF R R R n is an integer from 0 to 2, and prodrug esters and pharmaceutically acceptable salts thereof; wherein the term “prodrug esters” refers to esters and carbonates formed by reacting one or more free hydroxyls, that is, where any of R, R′ and/or R″ is H, of the compound of formula I with alkyl, alkoxy, or aryl substituted acylating agents.