Patent ID: 8980257
Filing Date: 2015-03-17
Classification: A61K,A61P,C07K

Abstract:
1. An antibody that specifically binds to human TGF-α, wherein the antibody comprises any one of the following characteristics (a) to (h): (a) a light chain variable region including the amino acid sequences of SEQ ID NOs: 19 to 21, and a heavy chain variable region including the amino acid sequences of SEQ ID NOs: 22 to 24; (b) a light chain variable region including the amino acid sequences of SEQ ID NOs: 25 to 27, and a heavy chain variable region including the amino acid sequences of SEQ ID NOs: 28 to 30; (c) a light chain variable region including the amino acid sequences of SEQ ID NOs: 31 to 33, and a heavy chain variable region including the amino acid sequences of SEQ ID NOs: 34 to 36; (d) a light chain variable region including the amino acid sequences of SEQ ID NOs: 37 to 39, and a heavy chain variable region including the amino acid sequences of SEQ ID NOs: 40 to 42; (e) a light chain variable region including the amino acid sequences of SEQ ID NOs: 43 to 45, and a heavy chain variable region including the amino acid sequences of SEQ ID NOs: 46 to 48; (f) a light chain variable region including the amino acid sequences of SEQ ID NOs: 49 to 51, and a heavy chain variable region including the amino acid sequences of SEQ ID NOs: 52 to 54; (g) a light chain variable region including the amino acid sequences of SEQ ID NOs: 55 to 57, and a heavy chain variable region including the amino acid sequences of SEQ ID NOs: 58 to 60; and (h) a light chain variable region including the amino acid sequences of SEQ ID NOs: 61 to 63, and a heavy chain variable region including the amino acid sequences of SEQ ID NOs: 64 to 66.