Patent ID: 8318169
Filing Date: 2012-11-27
Classification: A61K,A61P,C07K

Abstract:
1. An extruded biodegradable intraocular implant consisting of: a) about 70-85% by weight of a biodegradable polymeric carrier, wherein the biodegradable polymeric carrier is a poly-lactide-co-glycolide (PLGA); b) about 10-20% by weight of a water soluble therapeutic agent; and c) about 5-10% by weight of a saturated straight chain alcohol 16 to 26 carbon atoms in length; wherein the therapeutic agent is selected from the group consisting of peptides, proteins, antibodies, and antibody fragments; and wherein a therapeutically effective amount of the therapeutic agent is released from the biodegradable intraocular implant for at least one week after the intraocular implant is placed in the eye.