Patent ID: 9023317
Filing Date: 2015-05-05
Classification: A61K,C07B,C07C,C07D,C07K,C08F

Abstract:
1. A method of synthesizing a radiolabeled benzamide on a solid support comprising: a) selecting a solid support comprising at least one compound attached to said solid support, wherein the compound is selected from the group consisting of: b) reacting said compound with at least one acid to afford a benzoic acid moiety or a carboxylic acid moiety; c) reacting said moiety of said compound attached to said solid support with at least one amine to afford a benzamide bound to a solid support; and d) reacting said benzamide bound to said solid support with a radioisotope; and an oxidant selected from the group consisting of chloramine-T,N-chlorosuccinimide, tert-butylhydroperoxide, iodogen, iodobeads and meta-chloroperbenzoic acid; to yield said radiolabeled benzamide.