Patent ID: 6962713
Filing Date: 2005-11-08
Classification: A01N,A61K

Abstract:
1. A spot-on formulation for combating parasites of an animal that consists of a parasitically effective amount of at least one ectoparasiticidal compound (A), a parasitically effective amount of at least one endectocidal parasiticide compound (B); a vehicle for localized cutaneous application to the animal, with absorption and a resultant plasma concentration of the endectocidal parasiticide; a crystallization inhibitor, and optionally at least one antioxidant, wherein: compound (A) is an ectoparasiticide of the formula; compound (B) is a macrocycic lactoun endectocidal parasiticide selected from the group consisting of an avezmectin, ivermectin, abamectin and doramectin; the vehicle contains diethylene glycol monoethyl other and ethanol; or mixture of C the crystallization inhibitor is polyvinylpyrrolidone or a crystallization inhibitor pair consisting of polysorbate 80 and polyvinylpyrrolidone.