Patent ID: 6214315
Filing Date: 2001-04-10
Classification: A61K,A61P

Abstract:
A composition suitable for treating a solid mass tumor in a mammal which composition comprises:(a) a non-crosslinked, biocompatible, non-biodegradable polymer which polymer is insoluble in blood;(b) a biocompatible solvent which is an organic material liquid at least at body temperature of the mammal and which solubilizes said polymer with the proviso that when said solvent comprises water, the amount of water employed is sufficiently small that the dissolved polymer precipitates upon contact with the blood;(c) from about 0.1 to about 25 weight percent of a water insoluble radioisotope having from a radioactive content of from about 0.5 microcurie to about 100 millicuries with the proviso that when the radioisotope is either water soluble or water reactable, said isotope is used as a water insoluble salt; and(d) a non-radioactive contrast agent wherein the total amount of (c) and (d) is from about 7 to about 40 weight percent based on the entire weight of the composition.