Patent ID: 7273710
Filing Date: 2007-09-25
Classification: A61K,A61P,G01N

Abstract:
1. A method for screening a compound or a salt thereof that alters the binding property of Melanin Concentrating Hormone (MCH) or a salt thereof to a protein having the amino acid sequence of SEQ ID NO: 3, an amide, an ester or a salt thereof, said method comprising: combining a MCH derivative or a salt thereof, a protein having the amino acid sequence of SEQ ID NO: 3, an amide, an ester or a salt thereof, and a test compound in an assay; determining the amount of MCH derivative or a salt thereof that binds to a protein having the amino acid sequence of SEQ ID NO: 3 in the presence of said compound or in the absence of said compound; and comparing the amount of binding in the presence of said compound with the amount of binding in the absence of said compound; wherein said MCH derivative is a peptide comprising an amino acid sequence selected from the group consisting of: the 2 with the proviso that said MCH derivative is not a peptide comprising the 1