Patent ID: 7303924
Filing Date: 2007-12-04
Classification: B01J,C07B,C40B,G01N,Y02P,Y10S

Abstract:
1. A method of functionalising a solid support comprising, at the surface, hydroxyl or hydride functions comprising the following steps: a) grafting by covalent attachment at least one bifunctional molecule comprising a protected carboxylic acid function of formula (I) below: b) deprotecting the carboxylic acid functions which were not deprotected during the grafting step a); and, c) passivation of the residual hydroxyl or hydride functions of the support which have not reacted with said molecule(s) of formula (I); wherein step a) is carried out at a temperature of between 50 and 200° C. with a compound of formula (I) in which A is a monofunctional group.