Patent ID: 6384236
Filing Date: 2002-05-07
Classification: A61K,A61P,C07C,C07D

Abstract:
A compound of formula or a pharmaceutically acceptable salt thereof, whereinR1 is selected from the group consisting of methyl, ethyl, difluoromethyl and trifluoromethyl; R2 is (C1-C6)alkyl, (C3-C7)alkoxy(C2-C4)alkyl, phenoxy(C2-C6)alkyl, (C3-C7)cycloalkyl, (C6-C9)polycycloalkyl, phenyl(C1-C8)alkyl or indanyl wherein the alkyl portion of said R2 groups is optionally substituted with one or more fluorine atoms and the aryl portion of said R2 groups is optionally substituted with one or more substituents independently selected from the group consisting of (C1-C4)alkyl, (C1-C4)alkoxy and halogen; AA is â€ƒwherein p ranges from 1 to 4; and Y is NHOH or OH, with the proviso that when R1 is methyl or ethyl and R2 is (C1-C6)alkyl or (C3-C7)cycloalkyl, then Y is NHOH.