Patent ID: 7413660
Filing Date: 2008-08-19
Classification: B01D

Abstract:
1. A single pass method of continuously separating a target molecule from a solution mixture comprising steps of: providing a simulated moving bed apparatus comprising a plurality of filter cartridge modules, each filter cartridge module comprising a volume of stationary phase particulates adjacent a porous substrate layer and the volume of stationary phase particulates having a bed height of less than 1 centimeter, each filter cartridge module having a filter cartridge module inlet and a filter cartridge module outlet, the plurality of filter cartridge modules being in serial fluid connection; flowing a solution mixture comprising a target molecule continuously through the plurality of filter cartridge modules; binding the target molecule to the volume of stationary phase particulates to form a target molecule:stationary phase particulate product; removing a loaded filter cartridge module containing the target molecule:stationary phase particulate product from the solution mixture flow; separating the target molecule from the target molecule:stationary phase particulate product from the loaded filter cartridge to form an isolated target molecule product and a regenerated filter cartridge; and adding the regenerated filter cartridge module to the solution mixture flow.