Patent ID: 6855709
Filing Date: 2005-02-15
Classification: A61K,A61P,C07D

Abstract:
1. A compound of formula I: wherein W A is a phenyl or naphthyl ring, a five or six-membered heteroaryl ring, a eight to ten-membered fused heteroaryl ring, the five or six membered monocyclic heteroaryl ring and the eight or ten membered fused heteroaryl ring system each optionally containing up to three heteroatoms (O, N, S); or a nine membered fused heteroaryl ring system containing one to three heteroatoms (O, N, S); each of the five- or six-membered monocyclic heteroaryl ring and the eight- to ten-membered ring systems being optionally substituted with 1-4 of R; Each R is independently selected from H, halo, alkyl, cycloalkyl, substituted alkyl, —OH, alkoxy, substituted alkoxy, —SH, —S-alkyl, —S-substituted alkyl, —CN, —NO G is Each R Each R Each R Each R Each R wherein cycloalkyl is a cyclic alkyl moiety have between 3 and 7 carbon atoms; substituted alkyl is an alkyl moiety including 1-4 substituents selected from halo, cycloalkyl, cycloalkenyl, heterocycloalkyl, het, aryl, —OQ substituted alkoxy is an alkoxy moiety including 1-3 substituents —OQ het is a C-linked five-(5) membered heteroaryl ring having 1-4 heteroatoms selected from the group consisting of oxygen, sulfur, and nitrogen; a C-linked six (6) membered heteroaryl ring having 1-3 nitrogen atoms; a eight (8) membered bicyclic heteroaryl ring system having 1-3 heteroatoms selected from the group consisting of oxygen, sulfur, and nitrogen; and a ten (10) membered bicyclic heteroaryl ring system having 1-3 heteroatoms selected from the group consisting of oxygen, sulfur, and nitrogen; substituted het is a het moiety having 1-3 substituents selected from —OQ wherein heterocycloalkyl is a cyclic alkyl moiety having between 5 and 7 ring atoms, including 1-4 heteroatoms in the ring selected from the group consisting of oxygen, sulfur and nitrogen; wherein Q n is 0-1; and any racemic, optically active, tautomeric, stereoisomeric form, mixtures or pharmaceutically acceptable salt thereof.