Patent ID: 6265374
Filing Date: 2001-07-24
Classification: A61K,C07K,C12N

Abstract:
A method for treating or preventing inflammation in a subject by administering an effective amount of the peptide:I-A-B-C-D-E-F-G-H-II (General Formula I)whereasA is Ala, Gly, Val, Ser, Thr or absent,B is Ala, Gly, Val, Ser, Thr or absent,C is Ser, Thr or absent,D is Ser, Thr Asn, Glu, SArg, Ile, Leu or absent,E is Ser, Thr, Asp or absent,F is Thr, Ser, Asn, Arg, Gln, Lys, Trp or absent,G is Tyr or absent,H is Thr, Arg, Gly, Met, Met(O), Gys, Thr, Gly or absent,I is Cys or absent,II is Cys, an amide group, an ester group or absent,at least one of the amino acids optionally being substituted by a monomeric or polymeric carbohydrate or an alkyl ester or alkyl ether derivative thereof, such substitute being accomplished through hydroxyl and/or amino groups of the amino acids, and wherein the peptide comprises at least 4 amino acid residues, or a pharmaceutically acceptable salt thereof.