Patent ID: 7632821
Filing Date: 2009-12-15
Classification: A61P,C07H

Abstract:
1. A compound of structural formula I having the indicated stereochemical configuration: or a pharmaceutically acceptable salt thereof; wherein B is Y is N or CR R R R or a residue of structural formula: wherein alkylcarbonyl, alkyloxycarbonyl, cycloalkylcarbonyl, and cycloalkyloxycarbonyl are unsubstituted or substituted with one to three substituents independently selected from the group consisting of halogen, hydroxy, carboxy, C 1-4 alkoxy, amino, C 1-4 alkylamino, and di(C 1-4 alkyl)amino and wherein arylcarbonyl, aryloxycarbonyl, heteroarylcarbonyl, and heteroaryloxycarbonyl are unsubstituted or substituted with one to five substituents independently selected from R 9 ; Ar is phenyl unsubstituted or substituted with one to three substituents independently selected from the group consisting of halogen, C R R R each R R R R R R each R