Patent ID: 8242779
Filing Date: 2012-08-14
Classification: G01N,G01R

Abstract:
1. Nuclear magnetic resonance (NMR) method for detecting hydrogen peroxide, comprising the following steps: a) providing a liquid sample in a static magnetic field produced by a magnet arrangement; b) stimulating a spin signal in the sample by exciting the sample with a first electromagnetic pulse generated by electronic pulse generating circuitry, the first electromagnetic pulse having a frequency corresponding to the hydrogen NMR frequency in the static magnetic field; c) waiting for a first time period; d) refocusing the spin signal in the sample for a first number of times by a series of second electromagnetic pulses generated by the electronic pulse generating circuitry, each second electromagnetic pulse having a frequency corresponding to the hydrogen NMR frequency in the static magnetic field, said second electromagnetic pulses being separated by a first echo time, while sampling a first train of spin signals in between the second electromagnetic pulses; e) refocusing the spin signal in the sample for a second number of times by a series of third electromagnetic pulses generated by the electronic pulse generating circuitry, each third electromagnetic pulse having a frequency corresponding to the hydrogen frequency in the static magnetic field, said third electromagnetic pulses being separated by a second echo time while sampling a second train of spin signals in between the third electromagnetic pulses, wherein the second echo time is different from the first echo time, and wherein a first spin-spin relaxation time is derived from the first train of spin signals and a second spin-spin relaxation time is derived from the second train of spin signals, and wherein the presence of hydrogen peroxide is signaled if the quotient of the first spin-spin relaxation time to the second spin-spin relaxation time is different from one.