Patent ID: 8846105
Filing Date: 2014-09-30
Classification: A61K,A61L,A61P

Abstract:
1. A pharmaceutical dry powder composition comprising a mixture of spray-dried first microparticles that comprise human fibrinogen, and spray-dried second microparticles that comprise human thrombin, for use as a haemostat in the topical treatment of a mild or moderate bleeding wound with a time to hemostasis of less than 5 minutes, wherein the mixture has an X50 value between 5 and 50 microns, and wherein the wound is selected from minor abrasions, cuts, scrapes, scratches, burns, sunburns, ulcers, internal venous bleeding, external venous bleeding, and surgical interventions selected from those involving gastrointestinal system, on parenchymal organs; surgical interventions in the ear, nose and throat area (ENT) cardiovascular surgery, aesthetic surgery, spinal surgery, neurological surgery; lymphatic biliary, and cerebrospinal (CSF) fistulae air leakages during thoracic and pulmonary surgery, thoracic surgery, orthopaedic surgery; gynaecological surgical procedures; vascular surgery and emergency surgery.