Patent ID: 8404264
Filing Date: 2013-03-26
Classification: A61L,A61P,C12N,Y10T

Abstract:
1. A method of preparing a small diameter blood vessel from expanded poly-tetrafluoroethylene (ePTFE) comprising modifying a lumen of said small diameter blood vessel by coating the small diameter blood vessel through a spin-shearing method wherein said method comprises: a. coating a glass-rod with a polyester comprising a linear aliphatic diol monomer and an acid monomer selected from the group consisting of citric acid, malic acid, and combinations thereof by use of a mechanical stirrer; b. rotating said coated glass rod at a speed of about 300 rpm; c. contacting said rotating glass rod with ePTFE to form the coating; d. shearing the lumen of the graft by rotating the graft in a direction counter to the direction in which it is spinning in step (a); and e. optionally, repeating steps a to d.