Patent ID: 6251099
Filing Date: 2001-06-26
Classification: A61B,A61M,A61N

Abstract:
A method of delivering a compound through an epithelial tissue layer that normally serves as a barrier to molecular transport, the method comprising:(a) mixing the compound with a coupling medium to form a compound-coupling medium mixture;(b) contacting a surface of the epithelial tissue layer with the compound-coupling medium mixture;(c) placing a first side of a target material in contact with the coupling medium; and(d) exposing a second side of the target material to a pulsed laser beam to propagate one or more impulse transients from the first side of the target material into and through the compound-coupling medium mixture to contact and enter the epithelial tissue layer, whereby the epithelial tissue layer is made temporarily permeable enabling the compound to pass through the epithelial tissue layer.