Patent ID: 8435731
Filing Date: 2013-05-07
Classification: C12Q

Abstract:
1. A method for diagnosing BVDV in a persistently infected ruminant test animal comprising: a) obtaining a biological sample from a test animal and from a control animal seronegative for BVDV; b) contacting said sample with an agent having affinity for a differentially expressed CXCR4 marker comprising SEQ ID NO: 58; and c) diagnosing the presence of BVDV via detection of said differentially expressed BVDV marker, wherein an alteration in the expression level of said BVDV marker obtained from said test animal relative to that obtained from said seronegative control animal indicates said test animal is persistently infected with BVDV, and wherein said alteration is CXCR4 down-regulation.