Patent ID: 8304395
Filing Date: 2012-11-06
Classification: A61K,A61P

Abstract:
1. A method of reducing the severity of neoplasia, or treating neoplasia in a subject suffering from a sarcoma comprising the step of administering to said subject suffering from a sarcoma a compound represented by the structure of the general formula (I): wherein R R Y is either nothing or a spacer group ranging in length from 2 to 30 atoms, wherein said spacer comprises —CO-alkylene-NH—, —CO-alkylene-CO—or a combination thereof; wherein if Y is nothing the phospholipid moiety is directly linked to X via an amide bond and if Y is a spacer group, the spacer group is directly linked to X via an amide or an ester bond and to the phosphoethanolamine moiety via an amide bond; X is hyaluronic acid, wherein the sugar rings of the glycosaminoglycan are intact; and n is a number from 1 to 1000; and/or a pharmaceutically acceptable salt or a pharmaceutical product thereof.