Patent ID: 8426401
Filing Date: 2013-04-23
Classification: A61P,C07D

Abstract:
1. A compound of Formula (I) wherein i) substituted C ii) trifluoromethyl, iii) C iv) heteroaryl selected from the group consisting of thienyl, furanyl, thiazolyl, isothiazolyl, oxazolyl, pyrrolyl, pyridinyl, isoxazolyl, imidazolyl, furazan-3-yl, benzothienyl, thieno[3,2-b]thiophen-2-yl, pyrazolyl, triazolyl, tetrazolyl, and [1,2,3]thiadiazolyl; i) benzofused C ii) C iii) C iv) phenyl(C v) C wherein the phenyl substituent is optionally independently substituted with one to two substituents selected from the group consisting of bromo, chloro, fluoro, iodo, trifluoromethyl, trifluoromethoxy, and trifluoromethylthio; vi) phenyl-(Q)-methyl wherein Q is O or S; wherein phenyl is optionally substituted with trifluoromethyl, one to three fluoro or chloro substituents, or trifluoromethoxy; vii) pentadecanyl; viii) septadeca-8,11-dienyl; ix) nonadeca-4,7,10,13-tetraene-yl; x) nonadecanyl; xi) heptadec-8-ene-yl; or xii) 1-(4-cyanophenyl)piperidin-4-yl; i) C ii) C iii) C iv) trifluoromethyl; v) trifluoromethoxy; vi) trifluoromethylthio; vii) C viii) C ix) C x) NR xi) phenyloxy optionally substituted with C xii) 3,4-dimethylpyrazol-1-yl xiii) cyano; xiv) fluoro; xv) chloro; xvi) bromo; and xvii) iodo; with the proviso that a compound of Formula (I) is other than