Patent ID: 6150135
Filing Date: 2000-11-21
Classification: A61K,C07K,C12N,Y02A

Abstract:
An isolated TPx-2 nucleic acid molecule selected from the group consisting of; (i) a Dirofilaria TPx-2 cDNA molecule: (ii) a Dirofilaria TPx-2 mRNA molecule; (iii) a Brugia TPx-2 cDNA molecule; and (iv) a Brugia TPx-2 mRNA molecule, wherein said cDNA or mRNA molecule of (i), (ii), (iii), and (iv) encodes a protein having thioredoxin peroxidase activity, said protein comprising an amino acid sequence that is at least 90% identical to an amino acid sequence selected from the group consisting of SEQ ID NO:2 and SEQ ID NO:9.