Patent ID: 7074411
Filing Date: 2006-07-11
Classification: A61K,A61P,C07K,Y10S

Abstract:
1. A recombinant multimeric protein, comprising a) a polypeptide fusion monomer A, which consists of a C-terminal fragment of the α chain of C4BP containing one or two cysteine residues, wherein the C-terminal fragment is contained within the amino acid sequence represented by SEQ ID NO:7, and a polypeptide fragment which is heterologous in relation to said α chain, and b) a polypeptide fusion monomer B, which consists of a C-terminal fragment of the β chain of C4BP containing one or two cysteine residues, wherein the C-terminal fragment is contained within the amino acid sequence represented by SEQ ID NO:8, and a polypeptide fragment which is heterologous in relation to the β chain, monomer A and monomer B being linked to each other by a disulfide bridge between a cysteine of the α chain C terminal fragment and a cysteine of the β chain C-terminal fragment to form said multimeric protein.