Patent ID: 8030320
Filing Date: 2011-10-04
Classification: A61P,C07D

Abstract:
1. A compound of formula (I): wherein: R1 is hydrogen, (C R2 is one or more groups chosen from hydrogen, halogen, (C R3 is trifluoromethyl; R4 and R5 are hydrogen, or R4 and R5 taken together with the carbon atom to which they are attached form a saturated ring containing from 3 to 6 carbon atoms and optionally containing from 0 to 1 heteroatom chosen from O, N and S; R6 is hydrogen, halogen, (C R, R7 and R8 are, independently of one another, hydrogen, (C R7 and R8 taken together with the nitrogen atom to which they are attached may form a saturated, partially unsaturated or unsaturated ring containing from 5 to 7 carbon atoms and optionally containing, in addition, a heteroatom chosen from O, N and S(O) X is a nitrogen atom; Z is O, N and S(O) m is 0, 1 or 2; and n is 1, 2, 3, 4, 5 or 6; or a pharmaceutically acceptable acid addition salt thereof.