Patent ID: 9127061
Filing Date: 2015-09-08
Classification: A61K,A61P,C07K,C12N,G01N

Abstract:
1. A recombinant antibody which specifically reacts with an epitope existing in the amino acids at positions 551 to 654 of the amino acid sequence shown in SEQ ID NO: 38 that is the extracellular region of human CDH3, and has cytotoxicity against CDH3-expressing cells, and which comprises the CDR1, CDR2 and CDR3 of a heavy chain variable region (HV), respectively, consisting of the amino acid sequences shown in SEQ ID NOS: 25-27, and the CDR1, CDR2 and CDR3 of a light chain variable region (LV), respectively, consisting of the amino acid sequences shown in SEQ ID NOS: 28-30.