Patent ID: 6706744
Filing Date: 2004-03-16
Classification: C07C,C07D,G06Q

Abstract:
A compound which is selected from3-{4-[1-(4-cyclohexylphenyl)-3-(3-trifluoromethoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-trifluoromethoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-trifluoromethoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-trifluoromethoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-trifluoromethoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-bromophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-bromophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-trifluoromethyl-5-fluorophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-bromophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl-3-(3-trifluoromethyl-5-fluorophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-trifluoromethyl-5-cyanophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-chlorophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-trifluoromethyl-5-cyanophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-chlorophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex1-enylphenyl)-3-(3-chlorophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-methylsulfonyl-4-trifluoromethoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-methylsulfonyl-4-trifluoromethoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-methylsulfonylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-methylsulfonyl-4-trifluoromethoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-methylsulfonylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-tert-butylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-tert-butylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-tert-butylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3hydroxymethyl-4-trifluoromethoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-hydroxymethyl-4-trifluoromethoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-hydroxymethyl-4-trifluoromethoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-methylthiophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-methylthiophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-methylthiophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-iodophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-iodophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-iodophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-methylsulfonyl-4-butoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-methylsulfonyl-4-butoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-methylsulfonyl-4-butoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(2-butyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(2-butyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-isopropyl-[1,2,4]oxadiazol-5-ylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-isopropyl-[1,2,4]-oxadiazol-5-ylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[3-[1(S)-(4-chlorophenyl)ethyl]-1-(4-cyclohexylphenyl)ureidomethylbenzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-isopropyl-[1,2,4]oxadiazol-5-ylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[3-[1(S)-(4-chlorophenyl)ethyl]-1-(4-cyclohexylcyclohexyl)ureidomethylbenzoylamino}propionic acid, 3-{4-[3-[1(S)-(4-chlorophenyl)ethyl]-1-(4-cyclohex-1-enylphenyl)ureidomethylbenzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-methylphenylsulfamoylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-methylphenylsulfamoylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-methylphenylsulfamoylphenyl)ureidomethyl]benzoylamino]propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-ethylphenylsulfamoylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-ethylphenylsulfamoylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-methylphenylsulfamoyl-4-methylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-methylphenylsulfamoyl-4-methylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(2-isopropyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-methylphenylsulfamoyl-4-methylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(2-isopropyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-ethylphenylsulfamoyl-4-methylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-ethylphenylsulfamoyl-4-methylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(2-[2,2,2-trifluoroethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(2-[2,2,2-trifluoroethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(2-[2,2,2-trifluoroethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(5-methylsulfonylthiophen-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(5-methylsulfonylthiophen-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylcyclohexyl)-3-(5-methylsulfonylthiophen-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[3-biphenyl-2-ylmethyl-1-(4-cyclohexylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[3-biphenyl-2-ylmethyl-1-(4-cyclohex-1-enylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-trifluoromethyl-4-chlorophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(2,2,4,4-tetrafluorobenzo[1,3]dioxin-6-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl-3-(3-trifluoromethyl-4-chlorophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(2,2,4,4-tetrafluorobenzo[1,3dioxin-6-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(2,2,4,4-tetrafluorobenzo[1,3]dioxin-6-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3,3,4,4-tetrafluorobenzo[1,4]dioxin-6-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3,3,4,4-tetrafluorobenzo[1,4]dioxin-6-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-benzothiazol-2-yl-4-trifluoromethoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3,3,4,4-tetrafluorobenzo[1,4]dioxin-6-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-fluorophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-fluorophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-fluorophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-methylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-methylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-methylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-ethylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-ethylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-ethylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-nitrophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-nitro-4-methylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-nitrophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-nitro-4-methylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-nitro-4-methylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-cyanophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-cyanophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-phenoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-cyanophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3-phenoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-phenoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3,5-difluorophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3,5-difluorophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylcyclohexyl)-3-(3,5-difluorophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-trifluoromethoxybenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexy-1-enylphenyl)-3-(6-trifluoromethoxybenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(5-trifluoromethoxybenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(5-trifluoromethoxybenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(5,7-dichlorobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(5,7-dichlorobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(4,6-dichlorobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexenylphenyl)-3-(5-fluoro-7-trifluoromethylbenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(4,6-dichlorobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(5-trifluoromethyl-7-methoxybenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(5-fluoro-7-trifluoromethylbenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexenylphenyl)-3-(4-trifluoromethoxybenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(4-trifluoromethoxybenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(7-trifluoromethoxybenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(7-trifluoromethoxybenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(4-fluoro-6-trifluoromethylbenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(4-fluoro-6-trifluoromethylbenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(5,6-dichlorobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(5-bromobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(5-bromo-7-fluorobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(5-bromo-7-fluorobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(5-bromobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(5-trifluoromethylbenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(5,7-bis(trifluoromethyl)benzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(5-trifluoromethylbenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(5,7-bis(trifluoromethyl)benzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(6,6,8,8-tetrafluoro-6H-dioxino[5,4-f]benzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(6,6,8,8-tetrafluoro-6H-dioxino[5,4-f]benzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(5,6,-(tetrafluoroethylenedioxo)benzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(5-fluoro-6-trifluoroethylbenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(5-fluoro-6-trifluoromethylbenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(6,7-(tetrafluoroethylenedioxo)benzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(6,7-(tetrafluoroethylenedioxo)benzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(6-trifluoromethylthiobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(6-trifluoromethylthiobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(6,7-dichlorobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(6,7-dichlorobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(5-trifluoromethylthiobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(5-trifluoromethyl-6-cyanobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(5-trifluoromethyl-6-cyanobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(5-trifluoromethyl-7-methylbenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(5-trifluoromethyl-7-methylbenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(5-trifluoromethyl-7-cyanobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(5-trifluoromethyl-7-cyanobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexenylphenyl)-3-(5-trifluoromethyl-6-bromobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(5-trifluoromethyl-6-bromobenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(5-tert-butylbenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(5-tert-butylbenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(5-trifluoromethyl-7-methoxybenzothiazol-2-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-methylsulfonyl-4-methylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-methylsulfonyl-4-methylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-ethylthiophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-ethylthiophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-acetylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-acetylphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-chloro-4-cyanophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-chloro-4-cyanophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-chloro-4-bromophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-chloro-4-bromophenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-benzooxazol-2-yl-4-trifluoromethoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-benzooxazol-2-yl-4-trifluoromethoxyphenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohexylphenyl)-3-(3-(2-methyl-2H-tetrazol-5-yl)phenyl)ureidomethyl]benzoylamino}propionic acid, 3-{4-[1-(4-cyclohex-1-enylphenyl)-3-(3-(2-methyl-2H-tetrazol-5-yl)phenyl)ureidomethyl]benzoylamino}propionic acid, and 3-{4-[3-(3-cyano-5-trifluoromethylphenyl)-1-(4-cyclohex-1-enylphenyl)ureidomethyl]benzoylamino}propionic acid or any optical or geometric isomer or tautomeric form thereof including mixtures of these or a pharmaceutically acceptable salt thereof.