Patent ID: 6911444
Filing Date: 2005-06-28
Classification: A61K,A61P,C07D

Abstract:
1. A compound having the formula: the N-oxide, the pharmaceutically acceptable addition salt and the stereochemically isomeric form thereof, wherein: p represents an integer being 0, 1, 2, 3 or 4; X represents O, S, NR Y represents O, S, NR each R R R R R R each R each R R each R R hydrogen, C or R each R  wherein m is 1 to 4, n is 0 to 5, q is 0 to 2, r is 0 to 2 and s is 0 to 4; R R R R R R R W represents O or S; each Z independently represents O, S, NH, —CH —Z—R R R aryl represents phenyl optionally substituted with one, two or three substituents each independently selected from the group consisting of: nitro, azido, cyano, halo, hydroxy, mercapto, C Het wherein said heterocycle may optionally be substituted with one, or where possible, two or three substituents each independently selected from the group consist of: Het Het wherein said heterocycle may optionally be substituted with one, or where possible, two or three substituents each independently selected from the group consist of: Het Het Het Het wherein said heterocycle each independently may be substituted with, where possible, one, two, three or four substituents each independently selected from the group consisting of: hydroxy, mercapto, carbonyl, C Het wherein said heterocycle may optionally be substituted with one, or where possible, two or three substituents each independently selected from Het provided however that the compound of formula (I) contains at least one —C(═O)—Z—R 14 moiety.