Patent ID: 7018637
Filing Date: 2006-03-28
Classification: A61K,A61P,G01N,Y02A,Y10S

Abstract:
1. A multivalent immunogenic molecule, comprising: a carrier molecule containing at least one T-cell epitope, said carrier molecule comprising a multiple antigen peptide having a plurality of carrier peptide segments linked to each other through lysine groups in a dendritic structure, and at least two different bacterial capsular oligosaccharide fragments each from a different serotype, each said different bacterial capsular oligosaccharide fragment being linked by site directed glycoconjugation to a different one of said plurality of carrier peptide segments and each said different bacterial capsular oligosaccharide fragment containing at least one functional B-cell epitope, wherein said carrier molecule imparts enhanced immunogenicity to said at least two oligosaccharide fragments.