Patent ID: 6368634
Filing Date: 2002-04-09
Classification: A61K

Abstract:
Solid pharmaceutical preparation for oral administration for a substantially immediate release of an active agent with a low solubility, said preparation containing:(a) the active agent, said active agent dissolving in a liquid pharmaceutically acceptable solubilizer selected from the group consisting of (1) polyethyleneglycol, (2) polyethyleneglycol hydrogenated castor oil, (3) a mixture of polyethyleneglycol and polyethelenglycol hydrogenated castor oil and a (4) a mixture of water with (1), (2), or (3); (b) said pharmaceutically acceptable solubilizer as the only solubilizer present for forming a solution in which the active agent is dissolved, and (c) solid polymeric or inorganic particles on which said solution is fixed, said particles containing said solution being agglomerated in an agglomerate which is not a matrix or gel containing matrix or gel forming components which can cause the solid preparation to gel in water or in gastric medium.