Patent ID: 6140049
Filing Date: 2000-10-31
Classification: C12Q

Abstract:
A method for detecting a predisposition or susceptibility to prostate cancer in an individual, said method comprising detecting, in a biological sample from the said individual, alleles of the markers linked to the occurrence of prostate cancer in his family as indicative of the presence of a predisposition or susceptibility to prostate cancer, these markers being selected from the microsatellite markers included in one of the groups of markers consisting of: D1S235, D1S2678, D1S2785, D1S321, D1S2842 of chromosome 1, D1S252, D1S498, D1S305, D1S484, D1S196of chromosome 1, D2S155, D2S325, D2S2242, D2S2321, D2S317, D2S2319, D2S2382, D2S2249, D2S163, D2S339 of chromosome 2, D4S405, D4S2974, D4S2996, D4S428, D4S2978, D4S3019, D4S1592, D4S398, D4S2987, D4S3004, D4S3018, D4S392, D4S1543 of chromosome 4, D5S2002, D5S2117, D5S393, D5S414, D5S2011, D5S2017, D5S436, D5S2090, D5S2013 of chromosome 5, D11S898, D11S927, D11S908, D11S1345, D11S934, D11S1320 of chromosome 11, D13S1290, D13S1283, D13S1230, D13S1234, D13S265, D13S1300, D13S281 of chromosome 13 and all polymorphic markers localized in the regions situated between the above markers and determining whether said detected alleles are indicative of a predisposition or susceptibility to prostate cancer.