Patent ID: 6426365
Filing Date: 2002-07-30
Classification: A61K,A61P,C07C,C07D,Y02P

Abstract:
A compound represented by the formula (I-2): whereinRâ€² represents a substituted or unsubstituted C3-10 cycloalkyl group or a substituted or unsubstituted C5-8 cycloalkenyl group; each of X1, X2, X3, and X4 may be the same or different and represents a hydrogen atom; a halogen atom; a C1-4 alkyl group; a halo-C1-4 alkyl group; a C1-4 alkoxy group; a cyano group; a nitro group; an acyl group; or an aryl group; and Z1â€² represents a hydrogen atom; â€”Y1R1, wherein Y1 represents â€”COâ€” or â€”CSâ€”, and R1 represents a substituted or unsubstituted straight chain or branched C1-10 alkyl group; a C1-4 alkoxy group; a C1-4 alkylthio group; a substituted or unsubstituted amino group; a substituted or unsubstituted ureido group; a substituted or unsubstituted C3-10 cycloalkyl group; a substituted or unsubstituted C3-10 cycloalkyl C1-10 alkyl group; a substituted or unsubstituted aryl group; a substituted or unsubstituted aralkyl group; a substituted or unsubstituted arylalkenyl group; a substituted or unsubstituted arylthio group; a substituted or unsubstituted 5- or 6-membered heterocyclic group having 1-3 nitrogen, oxygen, or sulfur atoms; or a substituted or unsubstituted 5- or 6-membered heteroarylalkyl group, or â€”Sâ€”R2, wherein R2 represents a substituted or unsubstituted C1-4 alkyl group or a substituted or unsubstituted aryl group, or a prodrug compound, a pharmaceutically acceptable salt, a hydrate, or a solvate thereof.