Patent ID: 8906923
Filing Date: 2014-12-09
Classification: A61P,C07D

Abstract:
1. A compound of formula (I) wherein A represents —C≡C— or the X represents carbon or nitrogen, and when X represents nitrogen then the Z R R R R C aryl is phenyl; phenyl substituted with one, two or three substituents each individually selected from halo, hydroxy, C heteroaryl is furanyl, thiophenyl, pyrrolyl, pyrazolyl, imidazolyl, isoxazolyl, thiazolyl, triazolyl, tetrazolyl, isothiazolyl, thiadiazolyl, oxadiazolyl, pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl, benzo[1,3]dioxolyl, benzofuranyl, benzothiazolyl, indolyl, 2,3-dihydro-1H-indolyl, tetrahydrothiophenyl, or quinolinyl, wherein each heteroaryl may be substituted with one or two substituents each independently selected from halo, cyano, C or a pharmaceutically acceptable acid addition salt thereof.