Patent ID: 7691575
Filing Date: 2010-04-06
Classification: A61K,G01N

Abstract:
1. A method of identifying a composition for increasing an immune response, comprising: providing a recombinant T-cell comprising an expression vector comprising a promoter operably linked to a heterologous reporter sequence encoding a heterologous reporter polypeptide, wherein the promoter of said expression vector consists of SEQ ID NO: 1 and wherein the T-cell expresses the reporter polypeptide; contacting the T-cell with a test composition; and assaying an expression level or an activity of the expressed reporter polypeptide, wherein an increase in the expression level or activity of the reporter polypeptide after the T-cell is contacted with the test composition, versus in the absence of the test composition, indicates that the test composition increases an immune response, wherein the test composition is a plant extract.