Patent ID: 6034096
Filing Date: 2000-03-07
Classification: A61P,C07C,C07D

Abstract:
A compound of formula (I) ##STR7## wherein R' is hydrogen; A is adamantyl or a mono-, bi-, or tricyclic residue optionally partially or totally unsaturated, which can contain one or more heteroatoms selected from the group consisting of N, S, or O and optionally substituted by hydroxy, alkanoyloxy, primary, secondary, or tertiary amino, amino(C.sub.1-4)alkyl, mono- or di(C.sub.1-4)alkyl-amino(C1-4)alkyl, halogen, (C.sub.1-4)alkyl, and tri(C.sub.1-4)alkylammonium(C.sub.1-4)alkyl;is a chain of 1 to 5 carbon atoms optionally containing a double bond or a NR' group wherein R' is hydrogen or (C.sub.1-4) alkyl;R is hydrogen or phenyl;X is an oxygen atom or a NR' group wherein R' is hydrogen or (C.sub.1-4)alkyl or is absent;r and m are independently 0, 1, or 2;B is a phenylene or cyclohexylene ring;Y is hydroxy;with the proviso that a tricyclic group as defined for A is fluorenyl only when said fluorenyl is substituted by a tri(C.sub.1-4)alkylammonium(C.sub.1-4)alkyl group.