Patent ID: 7273928
Filing Date: 2007-09-25
Classification: A61K,A61P,C07K,C12N,C12Y,G01N,Y02A,Y10S

Abstract:
1. An isolated nucleic acid molecule comprising a nucleic acid sequence that codes for a Keyhole Limpit Hemocyanin 2 (KLH2) polypeptide and comprises at least one intron sequence, wherein said nucleic acid sequence is selected from the group consisting of, (a) a DNA sequence or the corresponding RNA sequence selected from the group consisting of: SEQ ID NO:20 (KLH2 domain b), SEQ ID NO:21 (KLH2 domain c), SEQ ID NO:22 (partial KLH2 domain d), SEQ ID NO:23 (KLH2 domain g), SEQ ID NO:24 (partial KLH2 domain h), SEQ ID NO:57 (KLH2 domain b′), SEQ ID NO:58 (KLH2 domain c′), SEQ ID NO:59 (KLH2 domain d′), SEQ ID NO:60 (KLH2 domain e), SEQ ID NO:61 (KLH2 domain f), SEQ ID NO:62 (KLH2 domain g′), SEQ ID NO:102 (KLH2 domain b″), SEQ ID NO:103 (KLH2 domain c″), SEQ ID NO:104 (KLH2 domain d″), SEQ ID NO:105 (KLH2 domain e″), SEQ ID NO:106 (KLH2 domain f″), SEQ ID NO:107 (KLH2 domain g″); and, SEQ ID NO:108 (partial KLH2 domain h″), (b) a nucleic acid sequence that hybridizes under stringent hybridization conditions of 0.55×SSC; 1% blocking reagent; 0.1% sodium dodecyl sulfate (SDS) at about 68° C. overnight, to a counter-strand of a nucleic acid sequence according to (a); and (c) a nucleic-acid sequence that has at least 90% sequence identity to one of the nucleic acid sequences described under (a).