Patent ID: 8226844
Filing Date: 2012-07-24
Classification: A61K,B22F,B82Y,H01F

Abstract:
1. A powder of a biocompatible magnetic nanocrystal bearing a surface reactive N-hydroxysuccinimide ester moiety, wherein the surface of said biocompatible magnetic nanocrystal is bonded with a biocompatible macromolecule and an alkyl-containing molecule simultaneously, wherein said biocompatible macromolecule bonded on the surface of said magnetic nanocrystal has one or more carboxyl groups for further covalently conjugating the magnetic nanocrystal to a biomolecule, and wherein said surface reactive N-hydroxysuccinimide ester moiety is obtained by converting said surface carboxyl group on the biocompatible macromolecule to a N-hydroxysuccinimide ester moiety.