Patent ID: 7964386
Filing Date: 2011-06-21
Classification: B82Y,G01N

Abstract:
1. A process of immobilizing biomolecules on porous silicon supports comprising: A) providing a porous silicon layer on a support by anodization of silicon doped in hydrofluoric acid; B) drying the silicon layer support produced in step A by nitrogen flow; C) inserting the silicon layer support produced in step B into a scanning electron microscope (SEM) and irradiating areas of the silicon layer having a minimum size lower than one μm and any spacing by an electronic beam with an electronic surface dose between 1 mC/cm D) extracting the silicon layer support produced in step C from the SEM and incubating the silicon layer support in a biomolecule solution having a concentration between 0.01 mg/ml and 100 mg/ml for an incubation time between 1 second and 2 hours at a temperature between 10° C. and 40° C.; E) rinsing repeatedly the silicon layer support produced in step D by deionised water and drying by nitrogen flow.