Patent ID: 8633208
Filing Date: 2014-01-21
Classification: A61K,A61P,C07D

Abstract:
1. A method for the treatment of depression, comprising administering a compound of formula (I), a pharmaceutically acceptable salt or solvate thereof, as the sole active agent to treat depression to a subject in need of treatment: wherein: X is independently selected from —CH group or a nitrogen atom (—N); W is independently selected from an aryl group, an heteroaryl or an heteroaryl group of Heteroaryl group of Formula II: wherein said aryl group is an unsubstituted or substituted phenyl, with one or more substituents independently selected from a halogen selected from the group consisting of fluorine (—F), chlorine (—Cl) and bromine (—Br), trifluoromethyl (—CF when W is an heteroaryl group it is independently selected from the following penta- or hexa-atomic heterocycles: 2-furyl, 3-furyl, 2-thienyl, 3-thienyl, pyrrole-2-yl, pyrrole-3-yl, pyridine-4-yl, pyridine-3-yl, pyrimidin-4-yl, wherein the heterocyclic ring may be substituted with one or two substituents independently selected from: R when W is an heteroaryl group of formula II, it is a benzocondensed-5 or -6 membered heterocycle, wherein: Z and Y are independently selected from: an oxygen atom (—O—), a sulphur atom (—S—), or the groups: —CHR Q is independently selected from the groups: —CHR R R R