Patent ID: 7833762
Filing Date: 2010-11-16
Classification: C12N,C12P

Abstract:
1. A method of producing L-lysine comprising: A) culturing an B) collecting the L-lysine from the medium or the wherein the a) increasing the copy number of the acs gene which encodes the acetyl-CoA synthetase, b) modifying an expression regulatory sequence of said gene, and c) combinations thereof, and wherein the acs gene is selected from the group consisting of: (i) a DNA comprising the nucleotide sequence of SEQ ID NO: 3 and (ii) a DNA that hybridizes with a nucleotide sequence which is complementary to the nucleotide sequence of SEQ ID NO: 3 under stringent conditions of washing in 0.1×SSC, 0.1% SDS at 60° C., and wherein said DNA encodes a protein with acetyl-CoA synthetase activity.