Patent ID: 6752834
Filing Date: 2004-06-22
Classification: A61B,A61F,A61L,Y10S

Abstract:
A membrane comprising a resorbable multi-layer membrane for use in vivo in the reconstruction of bone or cartilage tissue at a site of a defect in said tissue, said resorbable multi-layer membrane comprising a matrix layer for facing toward said defect, the matrix layer having a matrix consisting essentially of collagen II and having an open sponge-like texture, and at least one barrier layer for facing away from said defect so as to prevent ingrowth of undesirable tissue types into said defect, the barrier layer having a close, relatively impermeable texture, the at least one barrier layer consisting essentially of a barrier layer material selected from the group consisting of collagen I, collagen III and a mixture thereof, wherein said multi-layer membrane is formed by application of said matrix layer to said at least one barrier layer as a slurry, so that said matrix layer is adhered firmly to and in direct contact with said at least one barrier layer, wherein firm adherence of the matrix layer to said at least one barrier layer results essentially solely from application of said slurry to said at least one barrier layer.