Patent ID: 6380154
Filing Date: 2002-04-30
Classification: A61K,A61L,C07K,C08J,C12N,D01F

Abstract:
A method for altering the physical dimensions of a body tissue in a mammal, said method comprising:introducing into or onto said body tissue a composition comprising a liquid solution of a protein polymer of at least 15 kD which comprises alternating blocks of at least 2 units each of (a) an amino acid sequence of from about 3 to 30 amino acids which promotes protein crystallization and (b) an amino acid sequence element selected from the group consisting of an elastin-like element, a collagen-like element or a keratin-like element; wherein after said introducing step said protein polymer acquires a non-liquid form under physiological conditions in less than about 500 minutes, and wherein said protein polymer solution is capable of acquiring a non-liquid form without chemical crosslinking.