Patent ID: 6248309
Filing Date: 2001-06-19
Classification: A23G,A61K,A61Q,Y10S

Abstract:
A gum composition comprising:antimicrobial agent A and antimicrobial agent B in an amount effective to inhibit the growth of oral pathogenic bacteria selected from the group consisting of Actinomyces viscosus, Fusobacterium nucleatum, Porphyromonas gingivalis, Streptococcus mutans, and Streptococcus sanguis, antimicrobial agent A and antimicrobial agent B being selected from the group consisting of berberine, cedarwood oil, chloramphenicol, Glycyrrhiza glabra extract, juicy fruit basil oil, juniper berries oil, and lemon basil oil, wherein when antimicrobial agent A and antimicrobial agent B are combined at least one of antimicrobial agent A and antimicrobial agent B exhibit a minimum inhibitory concentration relative to at least one of the bacteria that is synergistically less than the minimum inhibitory concentration of the at least one antimicrobial agent alone.