Patent ID: 6420570
Filing Date: 2002-07-16
Classification: A01N,A61K,A61L,C07D

Abstract:
A psoralen compound, comprising:a) a substituent R1 on the 5â€² carbon atom, selected from the group consisting of: â€”(CH2)uâ€”NH2 â€”(CH2)wâ€”R2â€”(CH2)zâ€”NH2, â€”(CH2)wâ€”R2â€”(CH2)xâ€”R3â€”(CH2)zâ€”NH2, and â€”(CH2)wâ€”R2â€”(CH2)xâ€”R3â€”(CH2)yâ€”R4â€”(CH2)zâ€”NH2; â€ƒwherein R2, R3, and R4 are independently selected from the group consisting of O and NH, and in which u is a whole number from 3 to 10, w is a whole number from 1 to 5, x is a whole number from 2 to 5, y is a whole number from 2 to 5, and z is a whole number from 2 to 6; and b) substituents R5, R6, and R7 on the 4, 4â€², and 8 carbon atoms respectively, independently selected from the group consisting of H and (CH2)vCH3, where v is a whole number from 0 to 5, and wherein when R1 is â€”(CH2)2â€”NH2, R6 is H; or salts thereof.