Patent ID: 6517859
Filing Date: 2003-02-11
Classification: A61K,A61P,Y10S

Abstract:
A drug delivery vehicle for administering an effective amount of a neuro-active agent to the central nervous system of an animal in need thereof which comprises a neuro-active agent, other than dopamine, within a microsphere comprising a polymer selected from the group consisting of poly(lactide-co-caprolactone) copolymer, polycaprolactone, and polyhydroxybutyrate-polyhydroxyvalerate copolymer, said polymer (1) being permeable to the neuro-active agent, (2) being biocompatible with the tissues of the central nervous system, and (3) having kinetic characteristics that may be manipulated to allow for the permeation of the neuro-active agent through the polymer at a controlled rate and a predetermined period of time.