Patent ID: 6407244
Filing Date: 2002-06-18
Classification: A61P,C07D

Abstract:
A compound having the Formula (I): or a pharmaceutically acceptable salt thereof, wherein:each R1 is independently selected from the group consisting of â€”CH3, â€”CH2CH3, â€”CH2C6H5, â€”C(O)OC(CH3)3, â€”C(O)OCH2C6H5, and â€”C(O)CH3; R2 is selected from the group consisting of â€”H, C1-C12 straight chain alkyl, â€”CH2C6H5, â€”SiR10R11R12, â€”C(O)CH3, â€”C(O)C6H5, -2-tetrahydropyranyl, â€”OCH2OCH3, and â€”C(O)OCH2CCl3; R3 is selected from the group consisting of â€”H, C1-C12 straight chain alkyl, â€”CH(R14)(R15) wherein R14 and R15 are independently C1-C12 straight chain alkyl, â€”C(O)C1-C9 straight chain alkyl, â€”CH(OH)C1-C9 straight chain alkyl, â€”CH(Cl)C1-C9 straight chain alkyl, -(2-pyridyl)methyl, -(3-pyridyl)methyl, -(4-pyridyl)methyl, and â€”CH2C6H5, the â€”CH2C6H5 being unsubstituted or substituted on phenyl with one cyano or one or more halo, methoxyl, or trifluoromethyl groups; R10 is selected from the group consisting of C1-C4 straight or branched chain alkyl and â€”C6H5; R11 and R12 are independently C1-C3 straight or branched chain alkyl; R16 and R17 is â€”H; and m is an integer ranging from 1 to 5.