Patent ID: 6017510
Filing Date: 2000-01-25
Classification: A61K,Y10S

Abstract:
A peptide reagent comprising:a) a chemically synthesized chernotactic peptide selected from the group consisting of a peptide derived from platelet factor 4, a peptide derived from a bacterially-derived chemotactic peptide, a peptide derived from elastin, a peptide derived from tuftsin, a peptide derived from fibrinopeptide B and a peptide derived from fibrinogen B.beta.-chain; andb) a technetium-99m chelating moiety covalently linked to said peptide said moiety being capable of forming a neutral complex with technetium-99m; wherein the reagent when radiolabeled with technetium-99m provides an imaging agent capable of accumulating at a site of inflammation in a mammalian body in an amount sufficient to allow detection of said site by gamma scintigraphy.