Patent ID: 8735173
Filing Date: 2014-05-27
Classification: A61K,G01N

Abstract:
1. A composition used for diagnosing a lysosomal storage disorder (“LSD”) comprising: a set of capture antibodies conjugated to microspheres, each microsphere having a different specific capture antibody and having at least a first fluorophore and a second fluorophore wherein the first fluorophore and the second fluorophore are spectrally distinct, wherein the set of capture antibodies comprises antibodies capable of binding to α-iduronidase, α-glucosidase, LAMP-1, and saposin C; and wherein each microsphere conjugated to a specific capture antibody has a specific ratio of the first fluorophore to the second fluorophore; and wherein each microsphere conjugated to a specific capture antibody is spectrally distinct from a microsphere conjugated to a different capture antibody.