Patent ID: 6565885
Filing Date: 2003-05-20
Classification: A61K,A61P,Y02A,Y10S

Abstract:
A method for forming a powder comprising perforated microstructures for pharmaceutical applications by spray drying comprising the steps of:providing a feed stock comprising a bioactive agent, surfactant, and a blowing agent wherein said blowing agent is selected from the group consisting of fluorinated compounds, nonfluorinated oils, ammonium salts, alcohols, chloroform, ethyl acetate, acetone, nitrogen, carbon dioxide, camphor, and latex wherein the ratio of blowing agent/surfactant is between 1.0-60 w/w; atomizing said feed stock to produce dispersed droplets; drying said droplets to form perforated microstructures comprising said bioactive agent and surfactant; and collecting said perforated microstructures.