Patent ID: 7829570
Filing Date: 2010-11-09
Classification: A61P,C07D

Abstract:
1. A compound of the formula I, the racemic-diastereomeric mixtures, optical isomers, or pharmaceutically-acceptable salts thereof, wherein the dotted line in the structure of formula (I) represents an optional double bond; X is CR R R where Z  or a group optionally substituted with R  thiazolyl, benzofuranyl, 2,3-dihydrobenzofuranyl, indolyl, isoxazolyl, tetrahydropyranyl, tetrahydrofuranyl, piperidinyl, pyrazolyl, pyrrolyl, oxazolyl, isothiazolyl, oxadiazolyl, thiadiazolyl, indolinyl, indazolyl, benzoisothiazolyl, pyrido-oxazolyl, pyrido-thiazolyl, pyrimido-oxazolyl, pyrimido-thiazolyl and benzimidazolyl; R R Z Z R A is a covalent bond, —O—; —S—; —S(O)