Patent ID: 7638081
Filing Date: 2009-12-29
Classification: A61K,B29C,B29K

Abstract:
1. A process for the preparation of a device comprising a core which includes a pharmaceutically active agent covered by an outer coating which includes at least one opening communicating from the exterior of the device to the core, in which the outer coating is applied by injection molding said coating around said core, the process comprising: locating said core within a mold cavity surrounding the core, said mold cavity defining the required dimensions of the outer coating and also defining the required position, shape and dimensions of each said opening; injecting a fluid moldable thermoplastic material into said mold cavity; allowing the fluid moldable thermoplastic material to set, thereby forming the outer coating; and separating the device, comprising the core, the outer coating, and said at least one opening, from the mold cavity, in which the mold cavity has an interior surface, in which a space is provided between said interior surface of the mold cavity and the core, said space defining the required shape and dimensions of the coating, in which an internal member extends from the interior of the mold cavity, through each said opening during injection and setting of the fluid moldable thermoplastic material, to abut the said core and to define the shape and position of the opening through which the internal member extends, and in which part of said at least one said internal member is located outside the mold, and said at least one said internal member extends from the exterior of the mold into the mold cavity and is mounted for inward and outward movement relative to the mold cavity and resiliently biased against said core during injection and setting of the fluid moldable thermoplastic material.