Patent ID: 6133305
Filing Date: 2000-10-17
Classification: C07D

Abstract:
A compound having the chemical structure: ##STR251## wherein: R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are independently selected from the group consisting of hydrogen, alkyl, halo and S-sulfonamido;""A"" is a ring selected from the group consisting of tetrahydrobenzene, tetrahydrofuran, pyrrolidine, isatin, chromone, fluorene, benzo[b]furan and thieno[b]thiophene;said ""A"" ring is substituted with one or more groups independently selected from the group consisting of hydrogen, alkyl, trihalomethyl, cycloalkyl, alkenyl, alkynyl, aryl, heteroaryl, heteroalicyclic, hydroxy, alkoxy, aryloxy, thiohydroxy, thioalkoxy, thioaryloxy, sulfinyl, sulfonyl, S-sulfonamido, N-sulfonamido, N-trihalomethanesulfonamido, carbonyl, C-carboxy, O-carboxy, cyano, azido, nitro, halo, cyanato, isocyanato, thiocyanato, isothiocyanato, O-carbamyl, N-carbamyl, O-thiocarbamyl, N-thiocarbamyl, C-amido, N-amido, amino and --NR.sup.5 R.sup.6 ;R.sup.1 and R.sup.2 or R.sup.2 and R.sup.3 or R.sup.3 and R.sup.4 may combine to form a methylenedioxy or an ethylenedioxy group; and,R.sup.5 and R.sup.6 are independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, aryl, carbonyl, acetyl, sulfonyl, trihalomethanesulfonyl and, combined, a five-member or a six-member heteroalicyclic ring.