Patent ID: 8394832
Filing Date: 2013-03-12
Classification: A61K,A61P

Abstract:
1. A method of treating or managing an immunodeficiency disease or disorder, which comprises administering to a patient in need of such treatment or management a therapeutically effective amount of an immunomodulatory compound of formula (I), or a pharmaceutically acceptable salt, solvate, or stereoisomer thereof, wherein one of X and Y is C═O, the other of X and Y is C═O or CH2 , and R2 is hydrogen or lower alkyl; and wherein the immunodeficiency disease or disorder is adenosine deaminase deficiency, antibody deficiency with normal or elevated Igs, ataxia-telangiectasia, bare lymphocyte syndrome, common variable immunodeficiency, Ig deficiency with hyper-IgM, Ig heavy chain deletions, IgA deficiency, immunodeficiency with thymoma, reticular dysgenesis, Nezelof syndrome, selective IgG subclass deficiency, transient hypogammaglobulinemia of infancy, Wiskott-Aldrich syndrome, X-linked agammaglobulinemia, or X-linked severe combined immunodeficiency.