Patent ID: 8563543
Filing Date: 2013-10-22
Classification: A61P,C07D

Abstract:
1. A compound, or a tautomer or stereoisomer thereof, or a pharmaceutically acceptable salt of said compound, tautomer, or stereoisomer, said compound having the structural Formula (a): wherein: -L -L -L each -L m, n, p and q are each independently selected integers, wherein: m is 0 or more, n is 0 or more, p is 0 or more, q is 0 or more, wherein the maximum value of the sum of m and q is the maximum number of available substitutable hydrogen atoms on ring A, wherein the maximum value of n is the maximum number of available substitutable hydrogen atoms on ring B, and wherein the maximum value of p is the maximum number of available substitutable hydrogen atoms on ring C; R wherein each of said alkyl, haloalkyl, heteroalkyl, heterohaloalkyl, cycloalkyl, cycloalkylalkyl-, heterocycloalkyl, heterocycloalkylalkyl-, aryl, arylalkyl-, heteroaryl, and heteroarylalkyl- of R R wherein each of said alkyl, haloalkyl, aryl, arylalkyl-, heteroaryl, heteroarylalkyl-, cycloalkyl, cycloalkylalkyl-, cycloalkenyl, heterocycloalkyl, and heterocycloalkenyl of R R wherein each of said alkyl, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocycloalkyl, and heterocycloalkenyl of R ring A is selected from the group consisting of monocyclic aryl, monocyclic heteroaryl, monocyclic cycloalkyl, monocyclic cycloalkenyl, monocyclic heterocycloalkyl, monocyclic heterocycloalkenyl, and a multicyclic group; each R wherein each said alkyl, haloalkyl, haloalkoxy, heteroalkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl-, heterocycloalkyl, aryl, and heteroaryl of R ring B is selected from the group consisting of monocyclic aryl, monocycle heteroaryl, monocyclic cycloalkyl, monocyclic cycloalkenyl, monocyclic heterocycloalkyl, monocyclic heterocycloalkenyl, and a multicyclic group; each R wherein each said alkyl, haloalkyl, haloalkoxy, heteroalkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl of R each ring C (when present) is independently selected from the group consisting of monocyclic aryl, monocyclic heteroaryl, monocyclic cycloalkyl, monocyclic cycloalkenyl, monocyclic heterocycloalkyl, monocycle heterocycloalkenyl, and a multicyclic group; each R each R each R each R and each R wherein each said alkyl, haloalkyl, haloalkoxy, heteroalkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl of R