Patent ID: 6210932
Filing Date: 2001-04-03
Classification: C12Q,Y10T

Abstract:
A process for detecting at least one target nucleic acid sequence, comprising contacting said target sequence with at least one detection probe which consists of a nucleic acid molecule which consists of:an attachment domain A, which consists of a single-stranded polynucleotide;an intermediate domain B, which consists of at least one stop synthon; anda visualization domain C, which consists of a completely double-stranded polynucleotide having a size of from about 0.1 to about 50 kb and comprising at least 1/50 of labeled nucleotides based on the total nucleotides of said double-stranded polynucleotide,under conditions which enable the A domain of said detection probe to hybridize with the target sequence to form a hybrid, whereby the is detected by way of the C domain of the detection probe.