Patent ID: 6492152
Filing Date: 2002-12-10
Classification: A61K,C07H,C07K,C12N,C12P

Abstract:
An isolated polynucleotide which encodes a protein having core 1 &bgr;3-galactosyl transferase activity and which is selected from the group consisting of:(A) a polynucleotide selected from the group consisting of SEQ ID NO:2, SEQ ID NO:4, SEQ ID NO:6, SEQ ID NO:8, SEQ ID NO:10, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, SEQ ID NO:15 AND SEQ ID NO:18; (B) a polynucleotide which differs in nucleotide sequence from the isolated polynucleotides of (A) above due to degeneracy of the genetic code and which encodes a protein having core 1 &bgr;3-galactosyl transferase activity; and (C) a polynucleotide which differs in nucleotide sequence from the polynucleotides of (A) or (B) in that said polynucleotide lacks a nucleotide sequence which encodes a transmembrane domain wherein the core 1 &bgr;3-galactosyl transferase encoded is soluble.