Patent ID: 8968699
Filing Date: 2015-03-03
Classification: A61M,A61N,A61P

Abstract:
1. A nanosphere or nanodevice, comprising: (a) a layer, body or coating comprising an elastomeric material, wherein the layer, body or coating comprises a plurality of internal reservoirs or hollow depots each having a communication to the exterior; and (b) an outer polymer layer partially or completely covering the elastomeric material comprising a temperature-sensitive polymer, a temperature-responsive bio-compatible polymer or a bio-degradable temperature-responsive polymer comprising: wherein the outer polymer layer shrinks upon heating, resulting in partial or complete opening of the actuatable pores or nanopores, and cooling of the outer polymer layer partially or completely expands and closes or constricts the actuatable pores or nanopores, without destroying the integrity of the nanosphere or nanodevice.