Patent ID: 6156750
Filing Date: 2000-12-05
Classification: A61P,C07C,Y10S

Abstract:
A bicyclic aromatic compound having the structural formula (I): ##STR6## in which R.sub.1 is a radical --CH.sub.2 OR.sub.6 or a radical --CO--R.sub.10, R.sub.3 is a hydrogen atom or a lower alkyl radical; R.sub.2 and R.sub.4 together form, with the benzene ring from which they depend, a naphthalene ring member; R.sub.5 is a hydrogen atom, a halogen atom, a lower alkyl radical, an NO.sub.2 radical, a hydroxyl radical, a radial --OR.sub.7, a radical --O--COR.sub.7, or a radical: ##STR7## X is --O--, --S(O).sub.t -- or --NR.sub.12 --; Y and Z, which may be identical or different, are each --CR.sub.13 R.sub.14 --, --O-- or --S(O).sub.t --, with the proviso that Y and Z cannot simultaneously be an oxygen atom and cannot simultaneously be a radical --S(O).sub.t --; R.sub.6 is a hydrogen atom, a lower alkyl radical, or a radical --COR.sub.7 ; R.sub.7 is a lower alkyl radical; R is (a) a hydrogen atom, (h) a lower alkyl radical, (c) a radical: ##STR8## or (d) a radical --O--R.sub.11, wherein R.sub.11 is a hydrogen atom, a linear or branched alkyl radical having from 1 to 20 carbon atoms, an alkenyl radical, a mono- or polyhydroxyalkyl radical, or an optionally substituted aryl or aralkyl radical; R.sub.12 is a hydrogen atom, or a lower alkyl radical; R.sub.13 and R.sub.14 are each a hydrogen atom, or a lower alkyl radical; t is 0, 1 or 2; and R' and R"" are each, independently, a hydrogen atom, a lower alkyl radical, a mono- or polyhydroxyalkyl radical, an optionally substituted aryl radical or an aminoacid residue or sugar radical, with the proviso that R' and R"" may together form a heterocycle; or a pharmaceutically/cosmetically acceptable salt or optical or geometric isomer thereof.