Patent ID: 6696469
Filing Date: 2004-02-24
Classification: A61P,C07D

Abstract:
A compound selected from those of formula (I): wherein:X represents: a monocyclic or bicyclic, saturated, partially unsaturated or aromatic heterocycle, having from 5 to 12 ring members, containing from 1 to 3 hetero atoms selected from oxygen, nitrogen and sulphur but containing at least one nitrogen, the heterocycle being bonded to the remainder of the molecule by the nitrogen, and the heterocycle being optionally substituted, or a group of formula â€”NR2R3 wherein R2 represents hydrogen or linear or branched (C1-C6)alkyl, and R3 represents optionally substituted aryl, 1,3-dihydro-2H-benzimidazolyl-2-one, or linear or branched (C1-C6)alkyl substituted by a monocyclic or bicyclic, saturated, partially unsaturated or aromatic heterocycle, having from 5 to 12 ring members, containing from 1 to 3 hetero atoms selected from oxygen, nitrogen and sulphur but containing at least one nitrogen, the heterocycle being optionally substituted, n represents zero or 1, R1 represents hydrogen or linear or branched (C1-C6) alkyl, Ra represents a single bond or a linear or branched (C1-C6)alkylene chain, A represents nitrogen or CH, it being understood that A represents only CH when Ra â€œoptical isomersâ€  are understood to mean the enantiomers and diastereoisomers.