Patent ID: 8907111
Filing Date: 2014-12-09
Classification: A61K,A61P,C07D,C07H

Abstract:
1. A compound of formula I: wherein T is C(O)NH wherein R wherein the optional substituent is selected from one or more of the group consisting of: oxo, OH, F, Cl, Br, I, NH wherein zero to ten backbone carbons of the optionally substituted alkyl group are optionally and independently substituted with O, N or S; Z is F, Cl, Br, or OSO wherein R wherein the optional substituent is selected from one or more of the group consisting of: oxo, OH, F, Cl, Br, I, NH wherein zero to ten backbone carbons of the optionally substituted alkyl group are optionally and independently substituted with O, N or S; A is selected from the group consisting of: H, F, Cl, Br, OH, CN, OR wherein R wherein the optional substituent is selected from one or more of the group consisting of: oxo, OH, F, Cl, Br, I, NH wherein zero to ten backbone carbons of the optionally substituted alkyl group are optionally and independently substituted with O, N or S; D is selected from the group consisting of: H, F, Cl, Br, OH, CN, OR wherein R wherein the optional substituent is selected from one or more of the group consisting of: oxo, OH, F, Cl, Br, I, NH wherein zero to ten backbone carbons of the optionally substituted alkyl group are optionally and independently substituted with O, N or S; collectively, A and D, optionally form an oxo group; X is selected from the group consisting of: NH wherein R E is selected from the group consisting of: NH wherein R wherein the optional substituent is selected from one or more of the group consisting of: oxo, OH, F, Cl, Br, I, NH wherein zero to ten backbone carbons of the optionally substituted alkyl group are optionally and independently substituted with O, N or S; Q is selected from the group consisting of: CH wherein R each of J and G is independently selected from the group: H, OH, OAc, OC(O)CH wherein R M is H, OH, OAc, OC(O)CH L is H, OH, OAc, OC(O)R wherein R wherein the optional substituent is selected from one or more of the group: oxo, OH, F, Cl, Br, I, NH wherein zero to ten backbone carbons of the optionally substituted alkyl group are optionally and independently substituted with O, N or S.