Patent ID: 6162920
Filing Date: 2000-12-19
Classification: A61P,C07D

Abstract:
A taxane of the formula I: ##STR5## wherein Sk is ##STR6## R.sup.1 is hydrogen or C.sub.1 -C.sub.10 acyl, R.sup.2 is .alpha.-OH,R.sup.3 is C.sub.1 -C.sub.10 alkyl, X-substituted phenyl, or C.sub.1 -C.sub.10 alkoxy,X is hydrogen, halogen, --N.sub.3 or --CN,or a physiologically acceptable salt thereof, or phosphate or sulfate ester thereof,or ester or ether thereof with a physiologically acceptable water-soluble polymer,or a .alpha.-, .beta.- or .gamma.-cyclodextrin clathrate thereof.