Patent ID: 8071100
Filing Date: 2011-12-06
Classification: A61K,A61P,C07K,G01N

Abstract:
1. A substantially pure polypeptide comprising a fully human or humanized chimpanzee monoclonal antibody that binds or neutralizes anthrax lethal factor (LF), wherein said monoclonal antibody comprises a heavy chain CDR1 region having an amino acid sequence of SEQ ID NO:3, a heavy chain CDR2 region having an amino acid sequence of SEQ ID NO:5, a heavy chain CDR3 region having an amino acid sequence of SEQ ID NO:7, a light chain CDR1 region having an amino acid sequence of SEQ ID NO:11, a light chain CDR2 region having an amino acid sequence of SEQ ID NO: 13, and a light chain CDR3 region having an amino acid sequence of SEQ ID NO:15.