Patent ID: 9096579
Filing Date: 2015-08-04
Classification: A61K,A61P,C07D

Abstract:
1. A compound of formula 1 wherein R R R with A being a group selected from the group consisting of —CO—N(C wherein A may optionally be further substituted by one, two or three groups each independently selected from —C R or wherein R with Y being a group selected from the group consisting of —NH or with Y being a group selected from the group consisting of a four-, five-, six- or seven-membered monocyclic fully saturated or partially unsaturated heterocycle comprising 1, 2 or 3 heteroatoms each independently selected from N, S or O, a five- or six-membered monocyclic heteroaromatic group comprising 1, 2 or 3 heteroatoms each independently selected from N, S or O, —C or with Y being a 8- to 11-membered bicyclic annellated fully saturated, partially unsaturated or aromatic heterocycle comprising 1, 2, 3 or 4 heteroatoms each independently from each other selected from N, S or O, or with Y being an 8- to 11-membered bicyclic fully saturated spiro-heterocycle comprising 1, 2 or 3 heteroatoms each independently selected from N, S or O, with the proviso that this spiro-heterocycle comprises at least one N-atom and that this heterocycle is directly attached to the molecule via this N-atom, or with Y being a six- or seven-membered fully saturated heterocycle comprising 1, 2 or 3 heteroatoms each independently selected from N, S or O, which is bridged by an additional C whereby each Y may optionally be substituted by one, two or three groups Z each independently from each other selected from the group consisting of halogen, -oxo, OH, —CN, —C whereby each group Z may optionally be further substituted by one, two or three groups T each independently selected from the group consisting of -oxo, OH, halogen, —C wherein each group T may also optionally be substituted by a group selected from the group consisting of C whereby L denotes a 5- or 6-membered fully saturated or partially unsaturated heterocycle comprising 1 or 2 heteroatoms each independently selected from N, O or S, where the heterocycle may optionally be substituted by one, two or three groups independently selected from methyl, halogen, OH or -oxo; R or a pharmaceutically acceptable salt thereof.