Patent ID: 8969345
Filing Date: 2015-03-03
Classification: A61K,A61P,C07D

Abstract:
1. A compound of formula (I) [wherein Y is a hydrogen atom, lower alkyl optionally having substituent(s), lower alkoxy optionally having substituent(s), cycloalkyl optionally having substituent(s) or halogen, R X is any one of the formula (b1)-(b16) (wherein R A is any one of the formula (a1)-(a29) (wherein R wherein the substituents of the lower alkyl optionally having substituent(s), the lower alkylsulfonyl optionally having substituent(s), the lower alkenyl optionally having substituent(s), the lower alkynyl optionally having substituent(s), the lower alkoxy optionally having substituent(s), the lower alkylsulfanyl optionally having substituent(s), the lower alkanoyloxy optionally having substituent(s), the lower alkanoyl optionally having substituent(s), the lower alkoxycarbonyl optionally having substituent(s), the lower alkylcarbamoyl optionally having substituent(s), and the di-lower alkylcarbamoyl optionally having substituent(s) are the same or different and are 1 to 3 substituents selected from the group consisting of halogen, hydroxy, sulfanyl, nitro, cyano, carboxy, carbamoyl, C wherein the substituents of the aryl optionally having substituent(s), the aryloxy optionally having substituent(s), the aralkyl optionally having substituent(s), the aralkyloxy optionally having substituent(s) and the aromatic heterocyclic group optionally having substituent(s) are the same or different and are 1 to 3 substituents selected from the group consisting of halogen, hydroxy, sulfanyl, nitro, cyano, carbamoyl, C wherein the substituents of the cycloalkyl optionally having substituent(s), the aliphatic heterocyclic group optionally having substituent(s), the aliphatic heterocyclylcarbonyl optionally having substituent(s) and the nitrogen-containing heterocyclic group optionally having substituent(s) are the same or different and are 1 to 3 substituents selected from the group consisting of oxo, halogen, hydroxy, sulfanyl, nitro, cyano, carbamoyl, C wherein the nitrogen-containing heterocyclic group is a 5-membered or 6-membered monocyclic heterocyclic group with 3- to 8-membered rings fused together, containing at least one nitrogen atom (said monocyclic heterocyclic group may contain other nitrogen atom(s), oxygen atom(s) or sulfur atom(s)); or a bicyclic or tricyclic fused heterocyclic group containing at least one nitrogen atom (said fused heterocyclic group may contain other nitrogen atom(s), oxygen atom(s) or sulfur atom(s)), wherein the aliphatic heterocyclic group and the aliphatic heterocyclic group moiety of aliphatic heterocyclylcarbonyl are respectively, a 5-membered or 6-membered monocyclic aliphatic heterocyclic group comprising at least one atom selected from a nitrogen atom, an oxygen atom and a sulfur atom; or a bicyclic or tricyclic condensed aliphatic heterocyclic group with 3- to 8-membered rings fused together containing at least one atom selected from a nitrogen atom, an oxygen atom and a sulfur atom, and wherein the aromatic heterocyclic group is a 5-membered or 6-membered monocyclic aromatic heterocyclic group containing at least one atom selected from a nitrogen atom, an oxygen atom and a sulfur atom; or a bicyclic or tricyclic condensed aromatic heterocyclic group with 3- to 8-membered rings fused together, containing at least one atom selected from a nitrogen atom, an oxygen atom and a sulfur atom], or a pharmaceutically acceptable salt thereof.