Patent ID: 6573242
Filing Date: 2003-06-03
Classification: A61K,C07K

Abstract:
A composition for activating macrophages comprising S-(2,3-Dihydroxypropyl)-cysteine (Dhc)-peptide having two fatty acids, which fatty acids may be identical or different, bonded in the form of esters to the dihydroxypropyl group, the peptide having the following amino acid sequence (SEQ ID No 1):DhcGN NDE SNI SFK EK (SEQ ID No 1)â€ƒâ€ƒâ€ƒ2â€ƒâ€ƒâ€ƒâ€ƒ5â€ƒâ€ƒâ€ƒâ€ƒâ€ƒ10or an amino acid sequence that is identical to sequence (SEQ ID No 1) with an exception selected from the following group:(i) that the N-terminal amino acids in positions 2 (G=glycine) and, optionally 3, (N=asparagine) are absent, (ii) that the N-terminal amino acids in position 2 (G=glycine) and, optionally 3 (N=asparagine), are absent and one or two C-terminal amino acids are absent, and (iii) that one or two C-terminal amino acids are absent.