Patent ID: 6596732
Filing Date: 2003-07-22
Classification: A61P,C07D

Abstract:
A compound of formula: in which:n is 0, 1 or 2 and p is 0, 1 or 2; the sum n+p being equal to 1 or 2; R1 represents a halogen atom; a (C1-C4)alkyl; a (C1-C4)alkoxy; a trifluoromethyl radical; or a trifluoromethoxy radical; R2 represents a hydrogen atom; a halogen atom; a (C1-C4)alkyl; a (C1-C4)alkoxy; or a trifluoromethyl radical; or else R2 is in the 6-position of the indol-2-one ring and R1 and R2 together represent the bivalent trimethylene radical; R3 represents a halogen atom; a hydroxyl; a (C1-C2)alkyl; a (C1-C2)alkoxy; or a trifluoromethoxy radical; R4 represents a hydrogen atom; a halogen atom; a (C1-C2)alkyl; or a (C1-C2)alkoxy; or else R4 is in the 3-position of the phenyl and R3 and R4 together represent the methylenedioxy radical; R5 represents an ethylamino group; a dimethylamino group; an azetidin-1-yl radical; or a (C1-C2)alkoxy; R6 represents a (C1-C4)alkoxy; R7 represents a (C1-C4)alkoxy; R8 represents a hydrogen atom; a halogen atom; a (C1-C4)alkyl; or a (C1-C4)alkoxy; and R9 represents a hydrogen atom; a halogen atom; a (C1-C4)alkyl; or a (C1-C4)alkoxy; or a solvate or hydrate thereof.