Patent ID: 6965041
Filing Date: 2005-11-15
Classification: C07H,Y02P

Abstract:
1. A compound of the formula: wherein: R R R R wherein p is an integer from 0-6 and a-d are the same or different and each is selected from the group consisting of H, an alkyl, a nitro, an amino, a hydroxy, a thio, a cyano and a halogen; R Q is a nucleoside, an oligonucleotide having a nucleoside, or an oligomer having a nucleoside, wherein the nucleoside is of the formula: wherein: B is a labeling group, an alkyl, an alkenyl, an alkynyl, a cycloalkyl, an aryl, a heteroaryl, a heterocycloalkyl, an aralkyl, an amino, an alkylamino, a dialkylamino, a purine, a pyrimidine, adenine, guanine, cytosine, uracil, or thymine, wherein B is unsubstituted or substituted with one or more substituents, which are the same or different, selected from the group consisting of a protecting group, R E is H, a halogen, OR X is O, S, or Se, wherein the labeling group is a carboxyl to which is appended, via an amide linker, biotin, cholesterol, fluorenylmethoxycarbonyl (Fmoc), or trifluoroacetyl.