Patent ID: 8971489
Filing Date: 2015-03-03
Classification: A61N,G21K

Abstract:
1. A method of multileaf collimator (MLC) leaf positioning in tracking-based adaptive radiotherapy, comprising: a. determining a radiotherapy beam pattern in real-time during a radiotherapy treatment beam delivery, wherein said radiotherapy beam pattern comprises transforming a treatment beam plan into radiotherapy beam coordinates; b. determining a dose discrepancy between said radiotherapy beam pattern and a deliverable MLC aperture in said real-time during said radiotherapy treatment beam delivery, wherein said dose discrepancy comprises a sum of an overdose cost and an underdose cost to a treatment volume; c minimizing said dose discrepancy in said real-time during said radiotherapy treatment beam delivery according to instantaneous target motion, wherein said dose discrepancy minimization provides a determined deliverable MLC aperture for said radiotherapy beam that configures said multileaf aperture to shape a radiotherapy beam that optimally accounts for changes in a patient's anatomy measured during said radiotherapy treatment beam delivery; and d. collapsing a plan aperture f and an estimated anatomical motion T onto a beam-eye-view plane, wherein an ideal motion-compensated aperture is determined by composing said plane aperture f with said collapsed beam-eye-motion plane according to g=f°T, wherein said map is represented with a binary function over a region of interest (ROI), wherein said ROI: Ω→{0,1} so that  wherein x=(x, y) denotes a beam element location in said BEV.