Patent ID: 7795221
Filing Date: 2010-09-14
Classification: A61K,A61P,C07D,C07K

Abstract:
1. A linear peptide construct of formula III: wherein: Aaa  wherein the broken line indicates a peptide bond; R and R′ are independently H, a linear or branched C Aaa  where R and R′ are independently H or an amino acid side chain moiety of Ala, Nle, Leu, Val, Ile, Ser, Thr, Lys, Orn, Dap, or Dab or a derivative of an amino acid side chain moiety of Ala, Nle, Leu, Val, Ile, Ser, Thr, Lys, Orn, Dap, or Dab; x is 1 or 2; Y is CH Aaa Aaa Aaa Aaa Aaa Aaa Aaa Aaa Aaa Aaa Aaa Aaa Aaa  wherein the broken line indicates a peptide bond; at least one of R and R′ is (CH  x is 1 or 2; Y is CH with the proviso that at least one of Aaa