Patent ID: 7291744
Filing Date: 2007-11-06
Classification: A61K,C07C,C07D

Abstract:
1. A compound of formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, wherein: Z is selected from O and S; E is —(CH R R R R R R R R R R R R ring B is 1,2,3,4-tetrahydronaphthylenyl substituted with 0-3 R alternatively, ring B is selected from a C R R R R R R R R R R R alternatively, R R R R R R R R R R′, at each occurrence, is independently selected from H, C R alternatively, two R R R R R R R R R R R R R R R R alternatively, R R t is selected from 0, 1, 2, 3, 4, and 5, with the proviso that when s is 1, then t can not be 0; s is selected from 1, 2, 3, 4, and 5; r is selected from 0, 1, 2, 3, 4, and 5; q is selected from 1, 2, 3, 4, and 5; and p is selected from 0, 1, and 2.