Patent ID: 6740494
Filing Date: 2004-05-25
Classification: C07K,G01N,Y10S

Abstract:
A method for detecting the presence of a cancer in an individual, the method comprising the steps of:(a) contacting a body fluid sample from the individual with an antibody that binds specifically to a body fluid-soluble interior nuclear matrix protein that, when present at a concentration greater than a known standard, is indicative of the presence of a cancer in the individual, wherein the antibody is labeled with a detectable label such that the body fluid-soluble interior nuclear matrix protein, if present in the fluid sample, produces a labeled complex comprising the antibody and the body fluid-soluble interior nuclear matrix protein; and (b) assessing formation of the labeled complex, wherein the detectable label has a detection limit permitting detection of the labeled complex when the body fluid-soluble interior nuclear matrix protein is present at a concentration greater than the known standard.