Patent ID: 8329469
Filing Date: 2012-12-11
Classification: C12N

Abstract:
1. A cell culture article comprising: a swellable (meth)acrylate layer, wherein the swellable (meth)acrylate layer is formed from a composition comprising 2-carboxyethylacrylate, tetra(ethylene glycol) dimethacrylate, and one of hydroxyethyl methacrylate, hydroxypropyl methacrylate, 2-hydroxyethyl acrylate, 1-vinyl-2-pyrrolidone, di(ethylene glycol) ethyl ether methacrylate, acrylamide, ethylene glycol methyl ether methacrylate or 3-sulfopropyldimethyl-3-methacrylamidopropyl-ammonium; and a peptide comprising an amino acid sequence of XaanProGlnValThrArgGlyAspValPheThrMetPro (SEQ ID NO:1), wherein Xaa is any amino acid and n is an integer from 0 to 3; wherein the peptide is conjugated to the swellable (meth)acrylate layer; and, wherein the cell culture article has been sterilized by gamma irradiation.