Patent ID: 7847104
Filing Date: 2010-12-07
Classification: A61P,C07D

Abstract:
1. A process for preparing a compound having structural formula (I), wherein, R R R R Z comprising the steps of: (a) heating a mixture of a compound of formula (III), a base selected from the group consisting of sodium hydroxide, potassium phosphate and cesium carbonate, and a composition consisting of a compound of formula (IIa), a compound of formula (IIb) or a mixture thereof, wherein P is selected from the group consisting of alkoxyalkyl, alkylcarbonyl, alkoxycarbonyl, arylalkyl, arylcarbonyl and aryloxycarbonyl, R to provide a composition consisting of a compound of formula (IVa), a compound of formula (IVb) or a mixture thereof, wherein R followed by (b) treating the composition consisting of the compound of formula (IVa), the compound of formula (IVb) or the mixture thereof, to conditions that will provide the compound of formula (I).