Patent ID: 7230022
Filing Date: 2007-06-12
Classification: C07D

Abstract:
1. A compound of formula (Ia): or stereoisomers or pharmaceutically acceptable salts thereof, wherein: Z is selected from O or S; R R R R R R R R Y is selected from O, N(R ring B is a 5-7 membered cycloalkyl ring optionally containing a C═O, and being substituted with 0-2 R alternatively, ring B is a 5-7 membered saturated heterocyclic ring containing 0-1 O, N(R provided that if ring B is a heterocyclic ring, then the number of carbon atoms separating the heteroatom of ring B and the nitrogen atom of formula (Ia) bonded to R R R with the proviso that if R 6 is attached to a carbon atom which also is attached to a nitrogen atom, or if two occurrences of R 6 are attached to the same carbon atom, then r contained within the definition of such R 6 must be greater than 0; R R R R R with the proviso that if s is 1, then r contained within the definition of such R R R R′, at each occurrence, is in dependently selected from H, C R R R R R R R R R R R R R alternatively, R R R a is selected from 0 and 1; b is selected from 0, 1, 2 and 3; with the proviso that a+b is selected from 1, 2 and 3; c is 1; d is 1; m is selected from 0, 1, and 2; s is selected from 0 and 1; with the proviso: m+s is selected from 0, 1, and 2; v is selected from 0, 1, 2, and 3; with the proviso: that the number of atoms in the shortest path linking the nitrogen to which R r is selected from 0, 1, 2, 3, 4, and 5; t is selected from 0, 1, 2, 3, 4, and 5; q is selected from 1, 2, 3, 4, and 5; and u is selected from 0, 1 and, 2.