Patent ID: 6193985
Filing Date: 2001-02-27
Classification: A61K

Abstract:
A composition for the non-topical delivery of an active agent in the form of a non-liposomal emulsion comprising two phases:a) a first tocopherol-based phase comprising an active agent which is no more than sparingly soluble in water and which is not a tocopherol; andan amount of 20% to 95% w/w based on the total weight of the composition of at least one tocopherol or acetate, linoleate, nicotinate or hemi-succinate derivative thereof sufficient to dissolve the active agent in the tocopherol-based phase;b) a second phase comprising an emulsifying agent wherein the emulsifying agent is vitamin E TPGS; wherein said active agent is selected from the group consisting of antibiotics; antivirals; antimycotics; anti-amoebics; non-steroidal anti-inflammatory drugs; anti-allergics; immunosurpressive agents; coronary drugs; analgesics, local anaesthetics; anxiolytics, sedatives and hypnotics; migraine relieving agents; drugs against motion sickness; anti-emetics; disulfiram and vitamin K.