Patent ID: 6953810
Filing Date: 2005-10-11
Classification: A61P,C07D

Abstract:
1. A compound of Formula (1.0.0): wherein g is 1; j is 1; k is 0 or 1 m is 0, 1, or 2; n is 1 or 2; W W Y is ═C(R R  where R  where  where  and R  or R  where r and s are independently 0 to 4 provided that the sum of r+s is at least 1 but not greater than 5;  and X  and said spiro moiety of partial Formula (1.2.0) is substituted as to any one or more carbon atoms thereof, other than that defining X R R R  the following (a) —H; —F; —Cl; —(C  where p is 0, 1, or 2; and R (b) —(C (c) moiety selected from the group consisting of phenyl or benzyl; wherein said phenyl or benzyl moieties are each independently substituted with 0 to 2 substituents R R R  where R (d) R  wherein R Q  wherein said phenyl is substituted by R Q Z is “*” indicates the point of attachment of each partial Formula (1.1.1) through (1.1.15) to the remaining portion of Formula (1.0.0); R  the following: (1) —H; (2) —(C (3) —(CH  and (4) phenyl or benzyl, where said phenyl or benzyl is independently substituted by 0 to 3 substituents R  or a pharmaceutically acceptable salt thereof.