Patent ID: 8394630
Filing Date: 2013-03-12
Classification: A61K,A61P,C12N,G01N

Abstract:
1. A method of making a mammalian pluripotent cell population comprising obtaining a plurality of mammalian blastomere-like stem cells (BLSCs); culturing the BLSCs in a medium containing retinoic acid (RA) or transforming growth factor beta (TGF-I3) for a sufficient period of time to produce a pluripotent cell population that is 1-15 micrometers in size and expresses mRNA encoding GAPDH or beta-actin, and identifying and isolating the mammalian pluripotent cell population, wherein the pluripotent cell population differentiates into cells derived from ectoderm, mesoderm and endoderm germ layers.