Patent ID: 8642267
Filing Date: 2014-02-04
Classification: C12Q

Abstract:
1. A method for diagnosis of canine cancer, comprising the steps of: (1) obtaining a tumor sample from a canine subject, wherein the tumor is a canine transmissible venereal tumor or canine mammary gland tumor; (2) measuring the gene expression level of kynurenine 3-monooxygenase (KMO) gene in the tumor sample of step (1); (3) measuring the gene expression level of beta-actin in the tumor sample of step (1); (4) establishing a ratio of the expression level of KMO in the tumor sample compared to the expression level of beta-actin in the same tumor sample; and (5) determining the tumor sample of step (1) is a malignant tumor when the ratio of step (4) is larger than 0.00085, or the tumor sample is a malignant tumor with metastasis when the ratio of step (4) is larger than 0.004.