Patent ID: 6693112
Filing Date: 2004-02-17
Classification: A61P,C07D

Abstract:
A compound of the formula: or a pharmaceutically acceptable salt thereof, whereinR1 is H, alkyl (C1-C6), cycloalkyl, phenyl, or benzyl, wherein the alkyl and ring portion of each of the above is optionally substituted with 1, 2, or 3 groups that are independently alkyl (C1-C16), halogen, CF3, â€”OCF3, â€”OH, alkoxy (C1-C6), â€”CN, or â€”NO2, R3 is H, alkyl (C1-C4), halogen, alkoxy (C1-C4), â€”CF3, or â€”OCF3; R4 is H, alkyl (C1-C6), haloalkyl, â€”OH, alkoxy, hydroxyalkyl, â€”SH, â€”S-alkyl, â€”NO2, â€”NH2, mono- or dialkylamino, aminoalkyl, mono- or dialkylamino, phenyl, or benzyl; wherein the alkyl and ring portion of each of the above is optionally substituted with up to 4 groups that are independently alkyl (C1-C6), halogen, haloalkyl, â€”OH, alkoxy, hydroxyalkyl, â€”NO2, or â€”NRâ€²,Râ€³, wherein Râ€² and Râ€³ are independently H or alkyl (C1-C6); R7 is H, alkyl (C1-C6), alkoxy, or benzyl, wherein the alkyl and ring portion of each is optionally substituted with up to three groups that are independently alkyl, alkoxy, â€”NO2, â€”OH, halogen, â€”CN, â€”CF3, or â€”OCF3.