Patent ID: 6548684
Filing Date: 2003-04-15
Classification: B01J,C07B,C07C,C07D,C07F

Abstract:
Process for the coupling ofa) nucleophiles selected from the group of alcohols, thioles, amines, metallised hydrocarbons, CH-acidic compounds and metal cyanides, or of b) carbon monoxide mixed with water, alcohols, ammonia, primary or secondary amines, to organic compounds selected from the group of leaving-group-containing aromatics, hetero-aromatics with a C-bonded leaving group, aromatic or hetero-aromatic methyl compounds with a leaving group bonded to the methyl group, ethylenically unsaturated organic compounds with a C-bonded leaving group, or organic allyl compounds with a leaving group in allyl position, or c) vinyl compounds to organic compounds selected from the group of leaving-group-containing aromatics, while cleaving the leaving group m the presence of Pd complexes with monophosphine ligands as the catalyst, whereby variants b) and c) are carried out in the presence of an inorganic base or organic nitrogen base, and wherein the Pd complex contains secondary monophosphines with aliphatic, branched or cic substituents as ligands.