Patent ID: 6087122
Filing Date: 2000-07-11
Classification: A61K,A61P,C12N

Abstract:
A purified polynucleotide comprising a nucleic acid sequence which encodes a polypeptide comprising an amino acid sequence having at least about 80% homology to SEQ ID NO:3 and comprising at least one amino acid, relative to the position of SEQ ID NO:3, selected from the group consisting of V66, H70, A89, V108, G113, I122, I127, L134, S136, T145, A150, S151, S157, S159, K160, E162, D171, D175, G177, A178, R182, V184, S185, A225, T226, E228, N245, P271, T273, S380, T452, D650, and A752.