Patent ID: 6124317
Filing Date: 2000-09-26
Classification: A61K,C07D

Abstract:
A compound represented by the formula: ##STR54## or a pharmaceutically acceptable salt thereof wherein Ar.sup.1 is a monocyclic heteroaryl group, which may be independently substituted by hydrogen, hydroxy, alkyl, a halogenated alkyl group, halogen, nitro, aryl, aralkyl, amino, a lower alkyl amino group or a lower alkoxy group;Ar.sup.2 is independently aryl or a heteroaryl group, which may be independently substituted by hydrogen, hydroxy, alkyl, a halogenated alkyl group, halogen, nitro, aryl, aralkyl, or a lower alkoxy group;each R.sup.1 is independently hydrogen, alkyl or hydroxy;each R.sup.2 is independently hydrogen, alkyl or hydroxy;Z is --CH.sub.2 --, O, S or NR.sup.3 ;m is 0, 1 or 2; andn is 0, 1, 2, 3, 4 or 5;with the proviso that when Z is CH.sub.2, m is 0, n is 3, and R.sup.2 is hydroxy, Ar.sup.2 is not halogen substituted aryl.