Patent ID: 6833365
Filing Date: 2004-12-21
Classification: A61K,A61P,C07C,Y02A

Abstract:
A method for controlling Cryptosporidium parvum in a mammal, comprising administering to said mammal an effective amount of a tetracycline compound, such that Cryptosporidium parvum is controlled in said mammal, wherein said tetracycline compound is formula I: wherein:X is CHR6; R2, R4 and R4â€² are each hydrogen, alkyl, alkenyl, alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl, arylalkyl, heterocyclic, or heteroaromatic; R2â€², R3, R10, R11, and R12, are each hydrogen; R5 is hydroxy, hydrogen, thio, alkanoyl, aroyl, alkyl, heteroaromatic, alkyl, alkenyl, alkynyl, alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylamino, or an arylalkyl; R6, R7, and R8, are each independently hydrogen, hydroxyl, halogen, thio, alkyl, alkenyl, alkynyl, aryl, alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylamino, or an arylalkyl; R9 is alkyl or alkenyl, and pharmaceutically acceptable salts thereof.