Patent ID: 7407969
Filing Date: 2008-08-05
Classification: A61P,C07D,Y02P

Abstract:
1. A compound of formula N-oxide, addition salt, quatemary amine, metal complex or stereochemically isomeric form thereof wherein -a wherein each hydrogen atom in the radicals (a-2), (a-3), (a-4) and (a-5) may optionally be replaced by halo, C wherein =Z is ═O, =CH—C(═O)—NR Q is a radical of formula wherein Alk is C Y X X t is 2, 3, 4 or 5; u is 1,2, 3,4 or 5; v is 2 or 3; and whereby each hydrogen atom in Alk and the carbocycles and the heterocycles defined in radicals (b-3), (b-4), (b-5), (b-6), (b-7) and (b-8) may optionally be replaced by R G is a direct bond or C R and said bicyclic heterocycles may optionally be substituted in either of the two cycles with 1 or where possible more substituents selected from halo, hydroxy, amino, cyano, carboxy, C each n independently is 1, 2, 3 or 4; each m independently is 1 or 2; each p independently is 1 or 2; each R R R R R R aryl is phenyl or phenyl substituted with 1 or more substituents selected from halo, hydroxy, C Het is pyridyl, pyrimidinyl, pyrazinyl, or pyridazinyl.