Patent ID: 6277401
Filing Date: 2001-08-21
Classification: A61K

Abstract:
A drug delivery device which comprises:a) a moisture vapor permeable, liquid impermeable flexible thermoplastic backing layer possessing upper and lower surfaces;b) a moisture vapor permeable, flexible, oleophilic thermoplastic foam layer possessing upper and lower surfaces, the upper surface of the foam layer being nonadhesively bonded to, and substantially coextensive with, the lower surface of the backing layer;c) a pressure sensitive adhesive layer possessing a lower surface presenting a skin-contacting region and an upper surface adherent to, and substantially coextensive with, the lower surface of the foam layer; and,d) a drug reservoir possessing a lower drug-releasing surface and an upper drug barrier surface, the reservoir containing a medicinally effective amount of at least one hydrophilic drug composition, the drug reservoir further possessing a moisture vapor permeable, but hydrophilic drug composition impermeable, barrier layer having an upper and lower surface, its lower surface in adherent contact with the drug barrier surface of the drug reservoir and its upper surface contacting a portion of the lower surface of the pressure sensitive adhesive layer, wherein the barrier layer prevents any significant migration of the drug composition from the drug reservoir into the skin-contacting region of the lower surface of the pressure sensitive adhesive layer wherein the drug delivery device remains adhered to, and the drug-releasing surface of the drug reservoir remains in contact with, skin upon application of the drug delivery device thereto.