Patent ID: 7074405
Filing Date: 2006-07-11
Classification: A61K,A61P,B82Y,C07K

Abstract:
1. A method of treating diseased tissues in a patient, comprising: (A) administering to said patient a bi-specific antibody or antibody fragment having at least one arm that specifically binds a targeted tissue and at least one other arm that specifically binds a targetable conjugate; (B) optionally, administering to said patient a clearing composition, and allowing said composition to clear non-localized antibodies or antibody fragments from circulation; (C) administering to said patient a first targetable conjugate which comprises a carrier portion and one or more conjugated enzymes, wherein said carrier portion comprises or bears at least one epitope recognizable by said at least one other arm of said bi-specific antibody or antibody fragment; and (D) administering to said patient