Patent ID: 6777556
Filing Date: 2004-08-17
Classification: C07D

Abstract:
Process for preparing 2-haloalkylnicotinic acids and 2-haloalkylnicotinic acid derivatives, comprising reactinga) a compound of the formula (I) in which R1 is C1-C12-haloalkyl and R2 is C1-C12-alkyl with a compound of the formula (II) in which R3, R4 and R5 are each independently C1-C12-alkyl to give a compound of the formula (III) in which R1, R3, R4 and R5 are each as defined above, and b) reacting a compound of the formula (III) with ammonia or ammonium salts to give compounds of formula (IV) in which R1 and R5 are as defined above, c) optionally hydrolysing the compounds of formula (IV) to give compounds of formula (V) in which R1 is C1-C12-haloalkyl and R6 is M or hydrogen, where M is one equivalent of an alkali metal or half an equivalent of alkaline earth metal.