Patent ID: 8052996
Filing Date: 2011-11-08
Classification: A61K,Y10T

Abstract:
1. An implantable delivery system for an active agent formulation, comprising: a reservoir made of an impermeable material; a first chamber in the reservoir containing an osmotic engine; a second chamber in the reservoir containing an active agent formulation; a partition within the reservoir, the partition defining within the reservoir the first chamber containing the osmotic engine and the second chamber containing the active agent formulation; a semipermeable plug disposed at a first end of the reservoir adjacent the first chamber; and a flow modulator comprising (i) two pieces, an outer shell and an inner core, and (ii) an internal fluid channel, the flow modulator disposed at a second end of the reservoir adjacent the second chamber, the flow modulator comprising the outer shell positioned in an opening at the second end of the reservoir, the outer shell comprising an inner surface, the inner core inserted in the outer shell, the inner core comprising an outer surface, and the internal fluid channel having a spiral shape defined between the outer shell and the inner core.