Patent ID: 8038943
Filing Date: 2011-10-18
Classification: G01N

Abstract:
1. A method of detecting a presence of target bio-molecules or a concentration of the target bio-molecules using a field effect transistor, the method comprising: allowing a first sample including a first target bio-molecule to contact a sensing surface of the field effect transistor; flowing the first sample including the first target bio-molecule across the sensing surface of the field effect transistor without binding the first target bio-molecule to a fixed position; measuring a change in an electric signal of the field effect transistor, the field effect transistor comprising: determining a presence of the first target bio-molecule using the measured change in the electric signal of the field effect transistor, wherein changes in the electrical signal resulting from a change in pH due to the flowing of the first sample are disregarded in the determining of the presence of the first target bio-molecule.