Patent ID: 6063810
Filing Date: 2000-05-16
Classification: A61P,C07D

Abstract:
A compound of formula (I) in which:A represents either a hydrogen atom or a hydroxyl group,B represents either a hydrogen atom or a C.sub.1-8 alkyl, C.sub.1-8 alkenyl, C.sub.1-8 fluoroalkyl or C.sub.1-8 perfluoroalkyl group,R.sub.1, R.sub.2 and R.sub.5, which are identical or different, each represent a hydrogen atom, a halogen atom, or a C.sub.1-8 alkyl, C.sub.1-8 alkenyl, C.sub.3-8 cycloalkyl, C.sub.3-8 cycloalkenyl, C.sub.6, C.sub.10 or C.sub.14 aryl, C.sub.1-6 alkoxycarbonyl, C.sub.1-6 hydroxyalkyl, C.sub.1-6 alkoxyalkyl, C.sub.1-6 alkoxy, C.sub.1-8 fluoroalkyl or C.sub.1-8 perfluoroalkyl group,or R.sub.1 and R.sub.2 together form a C.sub.3-8 cycloalkyl, C.sub.3-8 cycloalkenyl or C.sub.6, C.sub.10 or C.sub.14 aryl ring, with the exclusion of the compounds in which R.sub.1 and R.sub.2 are simultaneously hydrogens and of 1-(dibenzofuran-2-yl)-2-isopropylaminoethanol,R.sub.3 and R.sub.4, which are identical or different, represent either a hydrogen atom or a C.sub.1-8 alkyl, C.sub.1-8 alkenyl, C.sub.3-8 cycloalkyl or C.sub.3-8 cycloalkenyl group,or R.sub.3 and R.sub.4 together form a C.sub.3-6 cycloalkyl or C.sub.3-6 cycloalkenyl ring, with the proviso that when R.sub.1 and R.sub.2 are each a methyl group, R.sub.3, R.sub.4, A and B are each a hydrogen atom and R.sub.5 is not a methoxy group,in the form of enantiomers or diastereoisomers or of mixtures of these forms, or of their addition salts with pharmaceutically acceptable acids.