Patent ID: 7858375
Filing Date: 2010-12-28
Classification: C07B,C40B,G01N,Y10T

Abstract:
1. A method of producing a supported lipid bilayer membrane via the following steps (i) providing a solid substrate surface; (ii) covalent attachment of a density between 1×10 12 /cm 2 and 1×10 14 /cm 2 of sterol groups to the solid substrate surface; (iii) and contacting the sterol functionalized solid substrate surface with a lipid solution to form a supported lipid bilayer membrane, wherein the resulting supported lipid bilayer membrane possesses air-stability and the said air-stability means that the supported lipid bilayer membrane remains intact on the substrate surface after the substrate has been removed from an aqueous solution, exposed to the ambient air at room temperature, and re-immersed in the aqueous solution.