Patent ID: 6207693
Filing Date: 2001-03-27
Classification: A61P,C07C,C07D,C07F

Abstract:
A compound of the formula: ##STR43##whereinR.sup.1 is aryl, substituted aryl, cyclo (lower) alkyl or substituted cyclo (lower) alkyl;R.sup.2 is hydrogen; lower alkyl optionally substituted with hydroxy, aryl or acyl; or cyclo (lower) alkyl;R.sup.3 is hydrogen; halogen; hydroxyl; acyloxy; substituted acyloxy; lower alkyl optionally substituted with hydroxy or lower alkoxy; lower alkoxy optionally substituted with aryl, amino, protected amino, acyl, hydroxy, cyano or lower alkylthio; nitro; amino; acyl; substituted acyl; or cyclo (lower) alkyloxy;A is a single bond or 0;E is lower alkylene or ##STR44##X is --CH.dbd.CH; --CH.dbd.N-- or S andY is benzimidazole or a substituted benzimidazole;or a pharmaceutically acceptable salt thereof.