Patent ID: 7038073
Filing Date: 2006-05-02
Classification: A61P,C07B,C07C,C07D

Abstract:
1. A method of preparing a compound represented by Structural Formula (I): or a salt thereof; wherein: R 1 is —H or a substituted or unsubstituted alkyl group; R 2 is a substituted or unsubstituted alkyl group; R 3 is —H, —(CH 2 ) x S(CH 2 ) y H, —(CH 2 ) x O(CH 2 ) y H, —(CH 2 ) x NH(CH 2 ) y H, —COOH, —CONH 2 , —NHC(NH)NH 2 , a substituted or unsubstituted alkyl group, a substituted or unsubstituted cycloaliphatic group, or a substituted or unsubstituted aromatic group, wherein R 3 optionally comprises a protecting group; x is an integer from 0–12; and y is an integer from 0–4; comprising the steps of: a.) reacting the compound represented by Structural Formula (III):  wherein:  with a nucleophile of the formula A-R b.) cleaving L-R