Patent ID: 6858747
Filing Date: 2005-02-22
Classification: C07D

Abstract:
1. A process for the manufacture of a benzylidene intermediate of formula wherein R 1 is C 1 to C 12 alkyl which is optionally substituted by a C 1 -C 4 alkoxyl, a trifluroromethyl or (C 6 H 5 CH 2 )(CH 3 )N and X and Y are independently selected from the group consisting of H, C 1 to C 6 alkyl, C 1 to C 6 alkoxy, C 1 to C 6 alkylaryl, halo, aryl, substituted aryl, and nitro, comprising the condensation reaction of an aldehyde of formula with an acetoacetate of formula in the presence of catalytic amounts of a pyridyl carboxylic acid of formula and a secondary amine.