Patent ID: 7795298
Filing Date: 2010-09-14
Classification: A61K,A61P,C07D,C07K

Abstract:
1. A method for the treatment of cancer in a subject, the method comprising administering to the subject a therapeutically effective amount of a compound represented by Formula I: or a pharmaceutically acceptable salt thereof, wherein: n is 0 or 1; m is 0, 1, or 2; p is 1 or 2; Y is NH, O, or S; A and A B and B BG is X and X L is selected from: R Q and Q Q and Q wherein G is a 5, 6, or 7 membered ring which optionally incorporates one or more heteroatoms chosen from S, N, or O, the ring being optionally substituted with one or more R R wherein the alkyl, alkenyl, alkynyl, cycloalkyl, and cycloalkenyl are optionally substituted with one or more R R wherein the aryl, heteroaryl, heterocyclyl, and heterobicyclyl are optionally substituted with one or more R R wherein the alkyl, alkenyl, alkynyl, cycloalkyl, and cycloalkenyl are optionally substituted with one or more R R wherein the alkyl, alkenyl, alkynyl, cycloalkyl, and cycloalkenyl are optionally substituted with one or more R or R R wherein the alkyl, alkenyl, alkynyl, cycloalkyl, and cycloalkenyl are optionally substituted with one or more R R wherein the alkyl, alkenyl, alkynyl, cycloalkyl, and cycloalkenyl are optionally substituted with one or more R R wherein the alkyl, alkenyl, alkynyl, cycloalkyl, and cycloalkenyl are optionally substituted with one or more R R R so as to treat the cancer, wherein the cancer is adrenal gland cancer, bone cancer, cardiac cancer, gastrointestinal cancer, genitourinary cancer, gynecological cancer, hematologic cancer, lung cancer, nervous system cancer, skin cancer, or breast cancer.