Patent ID: 7041856
Filing Date: 2006-05-09
Classification: B01J,C07B,C07D

Abstract:
1. A process for producing a coupling compound of formula (1): wherein R a substituted or unsubstituted aryl group, a substituted or unsubstituted heteroaryl group, or a substituted or unsubstituted linear, branched or cyclic alkenyl group, n and n′ independently represent an integer of 1 or 2, provided that n and n′ do not simultaneously represent 2, and when n=2, Y represents R which process comprises reacting an unsaturated organic compound of formula (2): wherein n, n′, and R X a leaving group and is bonded with a sp2 carbon atom of R with a boron compound of formula (3); wherein R X m represents an integer of 1 or 2, provided that the boron atom is bonded with a sp2 carbon atom of R m≦n, wherein n is the same as defined in connection with formula (1) above, or a cyclic anhydride trimer thereof of formula: (—O—B (R in the presence of a catalyst comprising (A) a nickel compound, and (B) a nitrogen-containing cyclic compound selected from the group consisting of: (a) a nitrogen-containing cyclic compound of formula (I): wherein Q represents a substituted or unsubstituted alkylene group, a substituted or unsubstituted alkenylene group, a substituted or unsubstituted 1,2-phenylene group, a substituted or unsubstituted 1,8-naphthylene group, or —N═N— group, R a substituted or unsubstituted hydrocarbon group, and R a hydrogen atom, a substituted or unsubstituted hydrocarbon group, alternatively, R (b) a substituted or unsubstituted pyridine or fused ring compound thereof of which conjugated acid has pKa of 5 or more, (c) a substituted pyrimidine or substituted or unsubstituted fused pyrimidine compound of which conjugate acid has pKa of 3 or more, (d) an enamine compound obtainable from a cyclic ketone compound and a cyclic secondary amine compound, (e) a substituted or unsubstituted 2H-pyrrole, 3,4-dihydro-2H-pyrrole or 3H-pyrrole or fused ring compound thereof, or (f) a substituted or unsubstituted N-hydrocarbyl 1,2,3-triazole, or a fused ring compound thereof.