Patent ID: 6258829
Filing Date: 2001-07-10
Classification: A61P,C07D,C07F

Abstract:
A cycloalka[b]pyridine-3-carbonylguanidine derivative represented by the following formula (1): ##STR11##(wherein R.sup.1 represents a halogen atom, a lower alkyl group, a lower alkoxylalkyl group; A represents a single bond; B represents a vinylene group or ##STR12##(wherein R.sup.3 represents a hydrogen atom, a halogen atom, a hydroxy group, a lower alkyl group, a lower alkylidene group, a lower alkoxyl group, a hydroxyower alkyl group, an aralkyl group, an aralkylidene group, a phenoxy lower alkyl group, a hydroxyimino group, a lower alkoxyimino group, an oxo group or a (CH.sub.2).sub.n ONO.sub.2 group (n is 0 or an integer of 1), and P* represents a tertiary carbon group or a carbon atom); D represents a single bond, a methylene group or an ethylene group; and E represents ##STR13##(wherein R.sup.4 represents a hydrogen atom, a halogen atom, which may be protected or an oxo group, R.sup.5 represents unsubstitution, a hydrogen atom or a lower alkyl group, P* represents a tertiary carbon group or a carbon atom, and Q represents a methine group or an oxygen atom)) or a salt thereof.