Patent ID: 6437165
Filing Date: 2002-08-20
Classification: A61P,C07F

Abstract:
A compound represented by formula 1: or a pharmaceutically acceptable salt or hydrate thereof, wherein:X is O, S, NR1 or (CH2)1-2, optionally substituted with 1-4 halo groups; R1 is H, C1-4 alkyl or haloC1-4 alkyl; R1a is H, OH, C1-4 alkyl, or OC1-4 alkyl, the alkyl and alkyl portions being optionally substituted with 1-3 halo groups; R1b represents H, OH, C1-4 alkyl or haloC1-4 alkyl; R2 is H, C1-4 alkyl or haloC1-4 alkyl, and R3 is H, OH, halo, OC1-4 alkyl or O-haloC1-4 alkyl.