Patent ID: 8198331
Filing Date: 2012-06-12
Classification: A61K,A61P,C07C,C07D

Abstract:
1. A method for treating a patient suffering from a disorder selected from the group consisting of non insulin dependent type 2 diabetes, insulin resistance, obesity, metabolic syndrome, hypertension, anxiety, major depressive disorder, psychotic depression, treatment resistant depression, panic disorder, post traumatic stress disorder, depression in Cushing's syndrome, cognitive deficits associated with diabetes and cognitive deficits associated with aging, and combinations thereof, comprising administering to the patient an effective amount of a selective inhibitor of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme activity, wherein said inhibitor is a compound of formula (I), or a pharmaceutically acceptable salt, prodrug, salt of a prodrug, or a combination thereof, wherein one of A n is 0 or 1; p is 0 or 1; D is selected from the group consisting of a bond, —C(R E is selected from the group consisting of a cycloalkyl, alkyl, and aryl, or R X is selected from the group consisting of a bond, —N(R R R R R R R R R R R R R R R R R R R R R R R R