Patent ID: 8394974
Filing Date: 2013-03-12
Classification: C07B,C07D

Abstract:
1. A process for producing an optically active chromene oxide compound represented by formula (14), formula (15), formula (16) or formula (17): (wherein R asymmetrically epoxidizing a chromene compound represented by formula (10), formula (11), formula (12) or formula (13) with an oxidizing agent in a solvent; (wherein R R R partial ring structure A in the formula (11) and formula (12) represents a partial structure being represented by 5-, 6- or 7-membered ring forming a fused ring with benzene ring part (each of the 5-, 6- and 7-membered rings may be optionally substituted with h R X in the formula (13) represents NR Y in the formula (13) represents a bond, SO or SO Z in the formula (13) represents a C W in the formula (13) represents a hydrogen atom, hydroxy group, C R by using any of optically active titanium complexes represented by the formula (1), formula (1′), formula (2), formula (2′), formula (3), formula (3′), formula (4) and formula (4′) as a catalyst, wherein R R R R M represents TiJ (wherein, in partial structure of O-E-O, O represents an oxygen atom and O-E-O is represented by following formula (6) in formula (1); O-E-O is represented by following formula (6′) in formula (1′); O-E-O is represented by following formula (7) in formula (2); O-E-O is represented by following formula (7′) in formula (2′); O-E-O is represented by following formula (8) in formula (3); O-E-O is represented by following formula (8′) in formula (3′); O-E-O is represented by following formula (9) in formula (4); and O-E-O is represented by following formula (9′) in formula (4′); and b represents an integer of 1 to 10; and R