Patent ID: 6221894
Filing Date: 2001-04-24
Classification: A01N,A61K,A61P,C07D

Abstract:
A compound having the formula I: ##STR8##or a pharmaceutically acceptable salt thereof, wherein R.sup.X is selected from the group consisting of: C(CH.sub.2 F).sub.3, and C(CH.sub.2 F).sub.2 CH.sub.3 ; or R.sup.X is a 1,1-dimethylpropyl, 1,1-dimethylprop-2-enyl, 3,4,4-trichlorobut-3-enyl, 1,1,2-trimethylprop-2-enyl, 1,1-dimethyl-2-trifluoromethylprop-2-enyl, 3-methyoxypropyl, 1,1-dimethylbutyl, 4,4,4-trifluorobutyl, 2,2,3,3,3-pentafluoropropyl, 3,3,4,4,4-pentafluorobutyl, 5,5,5-trifluoropentyl, 1-fluoromethyl-2-fluoroethyl, 1-methyl-2,2,2-trifluoroethyl, 2-fluoromethyl-3-fluoropropyl, 1,1-dimethyl-2,2,2-trifluoroethyl, 2,2-difluoropropyl, 3,3,3-difluorobutyl, 2,2-difluorobutyl, 2-methyl-3,3,3-trifluoropropyl, 2,2,3,3,4,4,4-heptofluorobutyl, 2,2-difluoro-3-methylbutyl, 2-methyl-3,3,3-trifluoropropyl, 3-methylbutyl, 1,1-dimethyl-2-oxo-4,4,4-trifluorobutyl, 1,1-dimethyl-2-oxo-5,5,5-trifluoropentyl, 3,1,1,3-trimethyl-2-oxobutyl, 1,1,3,3-tetramethyl-2-oxobutyl, (propyl 2-methylpropanoate)-2yl, (isopropyl 2-methylpropanoate)-2-yl, (phenyl 2-methylpropanoate)-2-yl, 1,1 -bis(fluoromethyl)-2-oxo-4,4,4-trifluorobutyl, 1,1-bis(fluoromethyl)-2-oxo-3,3-dimethylbutyl, 2,2-bis(fluoromethyl)-(N-methyl-N-ethyl)acetamide)-2-yl, ethyl 2,2-bis(fluoromethyl)acetate)-2yl, propyl 2,2-bis(fluoromethyl)acetate)-2-yl, isopropyl 2,2-bis(fluoromethyl)acetate, phenyl 2,2-bis(fluoromethyl)acetate)-2-yl, 1,1-dimethyl-2-oxopropyl, 1,1-dimethyl-2-oxobutyl, 1,1,3-trimethyl-2-oxobutyl, .alpha.,.alpha.-dimethyl-.beta.-oxophenethyl, or 2,3-dimethyl-3-hydroxy-2-butyl group.