Patent ID: 6380209
Filing Date: 2002-04-30
Classification: A61P,C07D

Abstract:
A pharmaceutical composition comprising a pharmaceutically acceptable carrier and a compound of the formula: or a pharmaceutically acceptable non-toxic salt thereof wherein:the C ring represents a thiophene or a pyridine, ring each of which is optionally substituted with one or two groups independently selected from a group consisting of C1-C6 alkyl, C1-C6 alkoxy, halogen, hydroxy, amino, mono- or di-(C1-C6)alkylamino, and trifluoromethyl; W is aryl or heteroaryl, each of which is optionally mono or disubstituted independently with halogen, hydroxyl, lower alkyl, lower alkoxy, amino, or mono- or dialkylamino where each alkyl portion is lower alkyl, or CONR4R5 wherein R4 and R5 are the same or different and represent lower alkyl; and R represents hydrogen, (C1-C6) alkyl, hydroxy(C1-C6)alkyl, amino (C1-C6) alkyl, mono- or di (C1-C6) alkyl, amino(C1-C6)alkyl, alkoxy(C1-C6)alkyl, (C1-C6)alkoxy, aryl(C1-C6)alkyl; or R represents CONR1R2 wherein R1 and R2 are the same or different and represent hydrogen or lower alkyl.