Patent ID: 6313131
Filing Date: 2001-11-06
Classification: A61K

Abstract:
A method of treating renal colic in a subject, comprising: administering to the subject in need thereof, a therapeutic effective amount of a compound of the formula: ##STR7##wherein R.sub.1 and R.sub.2, independently, are hydrogen or a C.sub.1 -C.sub.6 linear or branched alkyl optionally interrupted by a carbonyl;R.sub.3 is a C.sub.1 -C.sub.8 alkyl substituted by one or more moieties selected from the group consisting of hydroxyl, amino, mercapto, dioxolan, carbonyl and mixtures thereof; andR.sub.4 is hydrogen; a substituted or unsubstituted aromatic member selected from the group consisting of phenyl, biphenyl, benzyl, and furyl, wherein the substituent is selected from the group consisting of C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, halo and nitro; or a cycloalkyl selected from the group consisting of cyclohexyl and cyclopentyl; ora pharmaceutically acceptable acid addition salt thereof, in a unit dosage form.