Patent ID: 6436915
Filing Date: 2002-08-20
Classification: A61K,A61P,C07D

Abstract:
A composition comprising a compound of formula (1)or a stereoisomer, polymorph, solvate, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, diluent or excipient, where R1 is selected from alkyl, aryl and heteroaryl, wherein each of alkyl, aryl and heteroaryl may be substituted with one or more groups selected from C1-C20alkyl, C6-C10aryl, heteroalkyl and heteroaryl; R2 is selected from H and direct bond; R3 and R4 are selected from â€”NH2 and NHC(&boxH;O)R5; R5 is selected from R6, R7, and R8, where R6 is selected from alkyl, heteroalkyl, aryl and heteroaryl; R7 is selected from (R6)k-alkylene, (R6)k-heteroalkylene, (R6)k-arylene and (R6)k-heteroarylene; R8 is selected from (R7)k-alkylene, (R7)k-heteroalkylene, (R7)k-arylene, and (R7)k-heteroarylene; and k is selected from 0, 1, 2, 3, 4 and 5; and n is selected from 0, 1, 2, 3, 4 or 5.