Patent ID: 8124620
Filing Date: 2012-02-28
Classification: A61K,A61P,C07D

Abstract:
1. A compound of formula (I): wherein: m is 2; n is 1; p is 1, 2, 3 or 4; X is oxygen or NR′; Y is oxygen or sulfur; Z is NR′, a covalent bond, or a linker species, A; A is selected from the group —CR′R″—, —CR′R″—CR′R″—, —CR′═CR′—, and —C wherein when Z is a covalent bond or A, X must be nitrogen; Ar is an unsubstituted or substituted furanyl, pyrrolyl, thienyl, oxazolyl, isoxazolyl, pyrazolyl, imidazolyl, thiazolyl, or isothiazolyl; Cy is an unsubstituted or substituted pyridinyl, and the substituents are selected from the group consisting of alkyl, alkenyl, heterocyclyl, cycloalkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, halo (e.g., F, Cl, Br, or I), —OR′, —NR′R″, —CF r is an integer from 1 to 6 or a pharmaceutically acceptable salt thereof.