Patent ID: 6080758
Filing Date: 2000-06-27
Classification: A61P,C07D

Abstract:
A compound selected from the group consisting of:the compounds of the formula ##STR17## wherein X is a halogen atom,Q is an N-heterocyclic radical of the structure, ##STR18## A is a group --CH.sub.2 --, --CH(OH)-- or --CH(NH--COCH.sub.3)-- or a sulfur atom,R is a hydrogen atom or a group CO.sub.2 H, CO.sub.2 --B--R.sub.1 or CO--N(R.sub.2)--B--R.sub.1 whereB is a linear, branched or cyclic C.sub.1 -C.sub.10 -alkylene group,R.sub.1 is a hydrogen atom, a group CH.sub.2 OH, CH.sub.2 --O--CH.sub.3 or CH.sub.2 --NR.sub.3 R.sub.4 or a phenyl group,R.sub.2 is a hydrogen atom or a C.sub.1 -C.sub.4 -alkyl group,R.sub.3 is a hydrogen atom or a linear, branched or cyclic C.sub.1 -C.sub.10 -alkyl group,R.sub.4 is a hydrogen atpm or a linear or branched C.sub.1 -C.sub.10 -alkyl group, or NR.sub.3 R.sub.4 is a saturated heterocyclic radical having from 5 to 8 ring members and containing at least one nitrogen atom, and the carbon carrying the substituent R, when the ring Q is saturated, is of indeterminate (R,S) configuration or of determinate (R) or (S) configuration; and their addition salts.