Patent ID: 6136823
Filing Date: 2000-10-24
Classification: A61P,C07D,Y02P

Abstract:
A pyridonecarboxylic acid derivative or a salt thereof represented by the general formula (1): ##STR5## wherein R.sup.1 is a group --OR.sup.9 (wherein R.sup.9 is a hydrogen atom or carboxy-protecting group), amino group or lower alkyl-amino group; R.sup.2 is a hydrogen atom, nitro group, amino or hydroxyl group which may protected, lower alkyl group, or lower alkoxy group; R.sup.3 is a halogen atom, hydrogen atom, nitro group, lower alkyl group, lower alkoxy group or amino group; R.sup.4 is a nitro group, azido group, hydrazino group which may be substituted, group --NR.sup.10 R.sup.11 (wherein R.sup.10 and R.sup.11 may be the same or different from each other and are independently a hydrogen atom, lower alkyl group which may be substituted, lower alkenyl group, lower cycloalkyl group, saturated heterocyclic group or amino-protecting group), lower alkoxyl group or hydroxyl group; R.sup.5, R.sup.6 and R.sup.7 may be the same or different from one another and are independently a hydrogen atom, nitro group, halogen atom or lower alkyl group; R.sup.8 is a nitro group, amino group which may be substituted, hydroxyl group or lower alkoxyl group; A is a nitrogen atom or a group C--R.sup.12 (wherein R.sup.12 is a hydrogen atom, halogen atom, lower alkyl group which may be substituted, lower alkenyl group, lower alkynyl group, lower alkoxy group, lower alkylthio group or nitro group); and B is a nitrogen atom or group C--R.sup.13 (wherein R.sup.13 is a hydrogen atom or halogen atom).