Patent ID: 6204253
Filing Date: 2001-03-20
Classification: A61K,G01N

Abstract:
A method for modulating cell division regulation comprising the introduction to a cell in vitro at least one agent for binding with mdm2 in the cell, wherein the agent is a polypeptide encoded by a nucleic acid selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, and SEQ ID NO: 14, or a fragment of the polypeptide thereof that binds mdm2.