biogen it should be able to proceed in district court under section one forty six and secondly on the merits and they will not which presents the sport with a question of law asks the ultimate legal question of whether the patent disclosure the disclosure allows a person of ordinary skill to practice the invention here the arguments that were offered by mr clarke and the board's decision fail to engage the patent disclosure of identities let me start very briefly with two points on the jurisdictional issue we are aware of the by the decision and the limits of that places on a pad in deciding that the case was wrongly decided we're not asking the panel to do that there supreme court precedent does not control if the court determines that the prior panel would have reached a different conclusion if it considered control of precedent and we think that the rule that repeals of jurisdictional provisions must be express  was not briefed by the parties we looked at the briefs that were presented to the panel in the biotin case and that that is an issue that is open to this panel to decide in a footnote to it later through plasters that construction if the rosen line of cases follow will then allow the court to appoint a constitutional issue that we present also under the equal protection clause those are the two issues with regard to jurisdiction in which the court has questions on that i will turn to the can a person of ordinary skill make or use the invention from the disclosures in the patent without undue experimentation clerks or friends that it's a do experimentation was completely untether to the identical well i what i would tell you is that it look if you follow the left can't call and i confess that i'm not a chemist but i think i know enough to be dangerous here if you follow the left hand column and follow each of the steps that are listed including the underlined materials twenty three to be within well within that the ordinary skill one of the art and that brings us back to the failure of the board's decision it wouldn't leave clark's arguments one would expect in a case like this where those are the differences between the supposedly enabling junior party and the supposedly none of the of when senior party the focus of the board's decision will be on those differences but that couldn't be the difference th kill your people and that's really we're talking about dr griffon and usually one research assistant to the time what he was doing was completely into other to the specification it was there still he was sent out into the woods without a map he never a specification there's no evidence that he did and the evidence that he didn't is profound because he's trying to synthesize this as if it yes but he was trying to do it without the aid of specification so my questions h with entirely different starting materials he started with a two to primate hydro to i had a metal derivative that's nowhere set forth here when he goes on in the next few months a four one two seven eight s there was their expert testimony that he would have learned something specifications that he didn't learn from hawking and here was their testimony i mean you can talk all the chemistry we want with our job knowledge not brought up by our friends on the other side suggesting that the inventors gave him this path and in fact if the inventors gave him this path then there's no rational explanation for him to have started in an entirely different direction and take it entirely hopkins one of the questions at issue was whether the summary judgment just report case of that one of enablement was proper and there was a claim made on appeal that an expert's testing program had shown qaim for example says that that's not a requirement that there be a teaching that you have to select the specific offense in fact all concepts that it's irrelevant whether you even know that you have that in the original application that you've actually invented the target but here again i bring the court back to this this vertically oriented visual aid which is the comparison between our disclosure and the court discourse there's only one  what you see in our disclosure in the first instance which is on the other side of our cards handout excuse me that demonstrates that the inventions was unable but the judge newman go back to the board's decision here the board's decision contains a healthy discussion of the undue experimentation requirement of the wants factors and when used the most of it is rehearsal of the parties various arguments clark says store response that sort of thing and that wasn't tied to the specification and when you look at the conclusion of the court it's all based on the graph and work it's not time quite true because of the twenty three days thing in the application  this is under the amount of direction of guidance presented and we have met there is a gap there is the gap between what is shown the end product and the the precursor that hasn't been fluorinated but look at what else the court said of what the undo experimentation ruling that made it if there's any doubt about the board's failure to focus on the specification you can look at compare pages eight in pages thirty five of the board's decision page eight the board states the rule correctly it states the rule that we're looking to the specification we have to page a thirty five the board's ultimate conclusion is we therefore find that once factors one two three five and seven strongly indicate that a person skilled in the art would not undue experimentation there's no reference there whatsoever to the specification and if you'll know it's factors one two three five and seven they're called out by the court as being particularly relevant and one two and seven were all infected by i don't think that's right because we were designated as the senior party in the first instance so i think that the burden was on my friends on the other stuff you know ultimately our point with regard to remedy here is that it's not just that the board failed to do enough work like in  want to talk about because i know judge newman you had some questions about it this this does not reflect the three fifty specification really even close closely to what the specification actually shows and in particular i'd like to talk about spent a lot of time on what he called the vertically oriented sheet and what they have done here is what they did in front of the board of the board saw through it they have hunted through this two thousand page patent specification is that's what we're talking about here you have the the appendix up there too with four volumes are are this gigantic specification that has something for everybody in there and what they have done is they have picked one compound from column a one sixty one which describes this scheme three and they have judged the post it in their visual aid with a formula that is a thousand pages later in the specification that yes yes you can find it there but really the question on this appeal is is not just can you can you see it drawn out a sheet of paper can you make it is there any teaching in the specified cation of how someone of skill in the art could actually synthesize tha to make that specific precisely in here correct and here you had a group that you know with all due respect council says there's no link between dr fine and his failures in this specification dr fine was working with two of i've tried every way we can think of we've talked consult the experts they made suggestions that didn't work either nothing has worked and dr stuart does he says he thinks for a moment to say to dr graphology all you've got to do is go to my specification it's all laid out there board found he trying seven different routes ok ultimately he did try the route which identical his expert says would have been apparent to somebody of skill me art from this scheme later in the specification so the board said i see the argument you're trying to make i see the argument your expert is trying to make but the specification shows no synthesis roup at all for  indeed the board found there is no there's no synthesis root suggested for for anything any kind of nuclear side at all period in the specification so you don't have a starting compound you don't have a real agents you don't have a reaction conditions you don't have a root that's disclosed then do so the spec doesn't have and any of that then you look at the prior art well gee you know and there are simple cases of this court that say in a situation where the specification doesn't have it but if the prior art shows it and everybody knew it was in the prior art maybe you have enablement here it's undisputed the prior art and have either the board made specific findings of that there discount how had never before the well i think the reason for that was practically rahner and that was you don't even really have to get to the question of how the compound could have been used or might have been used because no one had been able to even make the compound or test the compound for activity so i me on this record it's undisputed that clarke my client was the first person to make it in in two thousand and three two thousand and two two thousand and three and ultimately his with his work was published but apparently a lot of these exploring i agree with you you know in the sense that there are many many many thousands of compounds disclosed a scientist could have looked at that and thought maybe that's one that i could try or should try and then the scientist says y reduction purpose right actually i'm talking from talking about both because i believe in this field in the chemical art it's not enough for conception to be able to drop out on a piece of paper you have to either disclose a viable synthetic route to make that compound or again to go back to my other exception that's recognized by the case well if the prior art already told you how to make it well then drawing it could be conception but but they don't have either thing here in the board made multiple findings on both of those issues so the person of skill looks at all these many many thousands of compounds could see that one of them is a two prime method of floral down yes specification doesn't tell me how aspect of the of the of the argument of council which was the teachings of the specification so so the board as i already said found that the spec doesn't disclose any foreign nation of any kind there's a lot of focus on this one compound in scheme three the so called two prime fee tone compound and identical says well if you if you take that as a starting point and you make a bunch of subsequent choices refines failures are not relevant because he's not tied closely enough to the three fifty specification and to the rather in the specification i already addressed that i just want to point out that we cited in our brief a couple of this court's cases leave that's correct your honor good morning joe abuse on behalf of the government united states intervened solely to address one issue that is the issue of the constitutionality of several acts of congress as available for a newly declared interferences and that you know full court having tonight on concrete hearings and the supreme court having denied search on this question that it's a binding decision that applies to this panel you're saying s apologize your honor i am here only to defend the constitutionality of the statutes as interpreted in biogen and if there are no further questions on that simple issue we believe that our preferred lays out the relevant facts and the law and so we're happy to rest on that brief i would only emphasize the simple question that is before this court and that is to decide the question of whether any conceivable set of facts could support a rational basis for the classification strong under beach communications a supreme court case it is irrelevant whether congress actually had that rational basis in mind when it enacted the statute there only must be a conceivable set of facts that would make it rational for congress to have drawn the lines that it did here we provide at least four reasons why congress could have rationally devised the lines that story now complains of and unless there are further questions we are happy to rest in the breeze thank you robert one point on jurisdiction and i think five points with regard to the merits on jurisdiction simply point out that the rosenkrantz rule regarding an express repeal of a jurisdictional provision was never addressed by the united states in this brief and never addressed by our friends that you lead in their brief either with regard to the merits also greeting that the two points this fifteen minute argument of twenty minutes probably by the time were all done here is the only hearing we're purposes of this case between the three fifty and the six hundred the provisional and the actual patent we include the entire patent in in the record that's the first two volumes but only excerpts of the provisional third the issue here dr marquez at thirty nine five twenty three and twenty four said big you will get this particular compound if you apply the before nation agents to it the car patent of course for it shows the same thing maybe strategically they found the o t m rule of one too many questions because they didn't want to know the answer because the part of the burden that's chargeable to them and their strategic choices should not deprive them of the opportunity should not which is reacting the mets to that compound seventeen with dest yes he did do that and he got six products and he analyzed one of them and you can't square that with their to their expert so testimony that if you react t