been different it turns out that what they actually used in those studies did correspond to the claims but that's not what the references disclose and quite frankly nor do they inherently disclose that under our law of inher how you want to mess up a lot of anticipation and inherently it's a straight forward it's never been articulated any differently than the document necessarily includes that and in this case you can't say this document necessarily includes it it turns out that study did in fact include it but the testimony of record was that any number of leaders five different coast solvents would have worked and different ratios would have worked and all the experts agreed on that so i don't understand how we would mess up the law of inherent see which is what you're asking us to do by concluding that even though the document doesn't necessarily result in someone understanding that this is what was used it should nonetheless be deemed to be inherently disclose most custom farms expert conceded a poster would not know that the prior art necessarily used a formula of forty percent castro and sixty percent then told them to wait and that is pointing to the expert testimony and a four zero four so in addition two strains of inherent see that we're discussing right now one is the one that i understand that judge moore is questioning you about which is when someone is reading those articles a person of ordinary skill in the art even though the articles don't express they say bends will bend so eight and a ratio of forty to sixty between castor oil and so bends away nevertheless a person of skill would necessarily understand while reading that reference in context aha there definitely pencil benzoate in here and it's at a forty to sixty ratio and that strain of inherent see you agree is not what you're advancing that fair to say it's a different strain which is that the actual formulation that was being used by those authors in those articles was necessarily the very formulation that's being reside in these claims and so even  but i guess that the concern i have about your argument is that what was disclosed in those articles was an incomplete disclosure of what that formulation was it gave you some of the ingredients but it didn't give you all the ingredients it's almost like the article had said we have this interesting new formulation for ministering to starstruck and we we've come up with this really special vehicle for administering it but i'm not going to tell you what my secret vehicle is and now i'm just going to report out the favorable results that i have from my secret vehicle do you think that would that would put the the invented vehicle in the possession of the public wants an article like that was occur during the primary i guess some is worried that if if there is some kind of formulation with five ingredients but let's say the author only chooses to identify one of the five ingredients and says i'm not going to tell you the other four and no one reading that article would be able to figure out what those other four are i don't know if we can say that that five ingredient formulation was actually disclosed and talked in that pr does get known it's obvious based on this article even though it wasn't disclosed and it's obvious as of that date earlier even though people didn't know it that's your problem your problem isn't that you want to use the information once it became known as of the data became known you want to use the information and give it the date of the articles from us it's for us as well what we want to say is that a publication is dedication to the public about its contained area and as a publicly later something new about that disclosure that information is not is not taken away but it wasn't contained therein that's your problem the information wasn't contained there  it wasn't the public didn't become in possession of that information until later in time look rather and it doesn't necessarily get contained therein so the kinds of cases you're talking about what you where it's even if the public doesn't know about it is aware there is a natural physiological response that will always happen to a particular drug that maybe people didn't know about it at the time but it always happens so once we learn that it always happens that disclosure necessarily included it because nothing else could've resulted in that but here any number of different code solvents could have resulted in what the article reported we just found out later what they actually use but any number of them could have it's not  are the public and titles but i guess you would agree that at the time those articles was published there was not enough information in those articles for someone else a person of skill in the art to go out and make and use that formulation is that fair to say no i wouldn't agree that it would then have to make a new formulation they would not however have known it was the i'm sorry did you did you agree or disagree with me i thought that time of those articles powerful absolutely and i think actually there are a good chance hypothetical that he posed to my friend is fitting in was one that was similarly used at the trial court level and i'd like to elaborate and give an example if the prior art included a letter or hypothetically from dean kamen that said i am about to come out with and invented it as a handlebar and goes really fast and then subsequently claimed in a subsequent patent segue that pr would not inherently anticipate the segway because it allows for both a bicycle to be described and a segway and the same issue is here where the prior art describes the formulation as and i would just quoth two hundred fifty other close off and at various different ratios so do the segway example where the prior describes a situation that allows for many different possibilities this court case is specific lee state and i would quote from was being discussed by the authors of those articles it was in fact it did have been doing it in the forty sixty ratio is not fair to say yes so in that sense we could say that an inherent characteristic of the composition being discussed in those articles were those particular features and so what i'm wondering is there are cases of our court like in ray krrish where there's in the prior art that disclosed genes and then later on someone else goes through all the effort and work of discovering an inherent characteristic of that gene the promoter  and then we said well nobody knew the details of that promoted region never less of an inherent characteristic of that prior art structure so then therefore  it's just there's no patentability here and so that's the struggle here and trying to understand how this fits within that kind of case law absolutely your honor and if you allow me i think both be in great chris and the atlas powder cases are sort of pressure on this point as you noted in krrish it was the promoter region of the human involvement team and then after this powder the inherent characteristic as you put it was itself such as here if the claim in the patent was to castor oil that contains let's say a one percent water content and the evidence at trial was that castor oil necessarily one hundred percent of the time at one percent water content that would be inherent but that's not what the claims in these patents say we're talking about mental bend wait a second ingredient in the formulation and the testimony at trial was a person of skill  among career going to get to the facts of crucial producer dorothy christie aling with the promoter region in the human development that promoter region is present the d n a sequence of that region is present one hundred percent of the time in the prior art the gene itself was in the prior art the record demonstrated the size of the promoter region and the plasmid of origin and this court in that case said even understanding that other practitioners other skilled artists and had tried to sequence that and come up with a different of that we know that the promoter region encrypt and one hundred percent of the time has that particular d n a sequence here it is not true that practicing the prior part one hundred percent of the time deal to a forty percent  i think another way to consider this problem is the idea of whether or not the use of this particular formulation in the prior art was invalidating is tantamount to a public use argument that argument was not made at the trial court level for sale you don't have to disclose all the little details of that product and it will still be an invalidating hack whereas for prior art references we don't seem to  have that kind of a flexible standard we require every d d biddy claim element to actually be disclosed or necessarily disclose in some way to your dancing the idea that even if the product is being discussed and disclosed you still need to actually describe of claim elements for it to be an invalid reference unlike the public use or that those claim elements would be necessarily present one hundred percent of the time i think if you look at the inherently cases of this court there is this idea of if practicing the prior art was necessarily practicing the subsequent claimed invention and that's where i think you get some of the marriage between the doctor and the but in this case the actual testimony of the record evidence upon which the district court made its factual findings is that there were possibilities to practice the prior practice that two hundred fifty milligrams to you in castor oil that could be practiced a number of different ways with a number of different poses often had a number of different ratios and it is that nature of the practice of the priority including many different formulation other than those claimed that is why the inherently doctrine has no place in this case apart from the inherently doctrine i don't understand the fact finding that it would not have been obvious or their witness been a motivation to lower the testosterone from one thousand milligrams to seven hundred fifty milligrams in light of the evidence of record that studies done with a thousand milligram showed that not cause a concern to a clinician more over we look at the conclusions of the prior articles themselves which do not address any sort of safety concerns and do suggested the overdose in fact they suggest to the contrary and sta expert admitted in a book that was edited and published contemporary as the critic dave here that of all the guideline ranges in the normal ranges at the time the ten to thirty five animal perth leader range was the you could extrapolate that there might be but there is no evidence in the prior art itself other than for that one patient other vigils who are actually outside of the prior vehicle and probably times one and your honor we don't dispute that proved on may have been one of the sort of things on the tool said of the inventor but the point here is that whether or not the district court and those articles show that the amount of castor oil was greater than sixty percent in order to achieve the potential long acting objective that was put forward in these patents and those can be found at appendix eleven fifty four sixteen twenty two and sixteen thirty seven that's the full the seven nine one tab reference and european patent seven ninety four those are the examples of formulations with castor oil and other testosterone testers