bodies produced five mice to be as human as possible and mouse genes were manipulated accordingly where general had a counterintuitive approach to realize that when mice were two human the anti bodies of the mice would produce would be fewer and weaker so instead of pursuing the trend of the more human the better it sought to produce a mouse that would produce anti bodies that were part human and part mouse and specifically that had a human variable region and a mouse constant one those antibodies of course would be directly put claims a four fifty six similar a four fifty seven and so on so that's the prosecution and then i now understand maris has also made the argument that we said something different claim construction or apply brief to page ten quotes the mark in brief and if you look at pages two to nine of the mark in brief it's very clear a general had a whole section called quote brief summary of her generous pioneering technology and not once does it refer to lift back or any other method here's the important point judge wallach about this the district court found that the patent was about a method not a mouse we think that was wrong and claim construction but we also think if you agree with that which is what the district court found it page eighty one eighteen of the broadest reasonable construction that mandates clear reversal of what the district court did because if the broadest result construction is this live back method which is what the district court says that that page none of these four asserted references had anything to do with the we think the district court got absolutely wrong here that is she cancel the trial all together on this key element of what is an equitable conduct which is one of the most grave things for patent prosecutors and for the p t o and indeed for a company as there are since recognized and here we weren't even allowed to have a trial and all the district courts reasoning on this was well there was some abuses of attorney client the scope of the waiver for attorney client privilege and i'm not here to disagree with that at this point that's janitors and we want to know why would what you're a so you agree that there were some problems in the conduct you spent covering disclose where it's too hard for us to argue we do disagree with them but it's too hard on the standard or view for us to raise those but we do think still if we accept everything she set the record regard to that then your argument is that therefore i mean what she described as at this juncture of the trial she would have to have a special master but we're looking all of the disclosures and going through all of the disclosures and that within her discretion that was not the appropriate way to proceed why is that an error because under controlling second circuit precedent in the relevant cases or sh deliberate intent to deceive the p t o indeed i think you know but even if not talk about money pages and i'll talk about that in a moment just walk but even at most all that would get is the exception to but for materiality when deal with chief judge proust point about specific intent because these are two separate elements there are since it's very clear you can't kind of mix and match from one to the other now here's the problem with what she had to find an affirmative religious materiality which is a narrow exception has to be sho convincing evidence the only thing maris's defending here is these slides in two thousand and thirteen and i think it's very important to drill down and see what happened with those slides those slides were introduced in the context of a p t o proceeding  we're attaching these slides which is to show unexpected results to defeat any form of payment about obviousness so there was no risk when the slides were introduced that there was going to be some sort of misleading of the p t o particularly not a to dismiss but you've got to show that and the no bad faith minding here that's the problem there were you know we did we don't as i was saying to chief judge press we don't disagree for purposes of this appeal that there were problems that were made but to go so it does require and it is our brief explains shane kong when it's dealing with cancelling an element or something like that you do have to show what you call willfulness but is translated in the second circuit as to bat day and that was a finding she didn't make and so she could have more than an inference she cancelled the trial all together on one of the two elements this court of their essence has said this is the atomic bomb the patent has such grave consequences not just to this company and not just to patent prosecutors who would th to kind of flood the p t o with all sorts of person you know possibly immaterial evidence possible or virtually relevant evidence but it also has consequences for the system as a whole and so that's really i think the problem that's why this court you know in direct misrepresentation about what had been done in relation of these so again judge well i don't feel that that is accurate so i think that those slides and most even under the smoke so called smoking gun document that they have says that the slides were quote correct but perhaps could be a little misleading and to the extent they were misleading they were in misleading on an element enablement which was just not issue in two thousand and one or two thousand and thirteen i don't think speed or anything like that was deliberate you know deception of the p t o and so i don't think that can get you into the specific intent that is required if i could spend a minute on the but for materiality and his for references there  three different ways of understanding the broadest reasonable construction here one is the district courts which i was saying to chief judge prost of page eighty one eighteen which is that it includes mice produced by the limp back method none of the four references have anything whatsoever to do with that if you take her b r c you've got to reverse the decision the second is our version of the b r c which is a reversed camero mouse that is that is a human variable in mouse constant constant genes there is no reference of these four that discloses anything like that the only way maris can win is by persuading you that the district court's b or c is wrong and that their b or c is right which is the claim claim one is only about the targeted insertion of human variable d n a and when you drill down and look at the references there's only one possible reference that goes to that the discloses the term it insertion of human d n a and that is one sentence i which is speculative and if you look at that one sentence and you can see our brief pages thirty eight lays out that sentence and compares it to what we did disclose creature left body in the opening brief page thirty nine there are almost exactly the same sentence the party do disclose everything and when miss carson comes up i think a key question will have to be what did these references disclose that weren't in our party or the hunger and i don't think the district court ever made that fundamental key thing we think that's the most important point for purposes of this appeal that specific intent is lacking and under any version of the broadest reasonable construction we when we do think that the judge made some other errors and claim construction ind efiniteness and claim construction the most important error we think the judge made was that she found it as a method and again if you do view it as a method then i think that kicks out the united will conduct finding because there's no nothing in these four references about that but i think it's just wrong and claim construction we have said all through this the text of the claim is very clear in the text of the claim disclose a patent on in my house it's not a pat on the mat there's no word method in there  that really the that then and that really that that that text settles the question and then the last issue set of issues is about indefiniteness and their merits his own expert i think gave up the store because the nurses expert good morning your honor it please the court i think it's important for the court to recognize that the judgment of non infringement in this case rests on three separate individual claim constructions affirming any one of construction you're out of the district court specifically found that even under that the references were but for material that was a finding of fact that the court made after hearing testimony crediting our dr davis our witness finding d construction the references were but form serial and i would direct the court's attention to the wood reference which absolutely under the fact findings of the district court does disclose what they want to call reverse  certainly weren't validating and how do we know that the claims of the patent would not have issued had regeneration disclose them well they were submitted in a level other applications now re generally makes this statement in their grief that those eleven other applications had different specifications but that's absolutely false they did not have the different specifications he can use we're looking at christmas because the claims the district court found were very very similar the district court walked through those and in every single one of those cases those references that  resolved by the terminal disclaimer and that would in the problem would i think that your honour's putting two concepts together what i'm trying to understand what are the points that you're because it's very hard to find any new specification in the prosecution where you can retrospective really find something to complain about and that's not the case here here we had fo murphy new of the references to how you do finally with your the materiality the way the court looked at it was that she knew that those references taught the very element that regeneration told the patent office was missing and that's insertion at the end dodginess mouse locus that's what they told the patent office was missing and that was what they told the patent office was missing for claims one through five locus and that's what every single one of those with help references taught so they were but for material because if you read how what the examiner said when she allowed the application that was what she had a trial and materiality at the same time we had to demonstrate that dr smee one murphy knew of the references that they made the affirmative decision to withhold the reference references so the adverse an unusual case the district court similar to the way it's done in the i t c she took the direct testimony in a written form so it was a written trial declaration that was given and doctors murphy and dr smeal and offered their direct testimony sworn testimony so at the same time though they wa extensively and so this was just the latest in a litany of misconduct this was the second time that they had waived privilege there were multiple motions to compel that involved the first waiver privilege and they never produce the documents and that's in the record but now the court is faced on the eve of trial with all the witnesses there my clients flown in from the netherlands and she's faced with extensive category were documents to directly contradicted what dr smeal and dr murphy said this is in the record so yes they offered their testimony and yes she found out that what they were saying was directly contradicted by the documents she couldn't have allowed them to testify under the circumstances so were not because she had been allowing them to perjure themselves basically why or i mean i suppose that amendment one might be appropriate but i don't know why a district court where you allow someone first party in order to as opposed to protection she engaged in sanctioning because at that point and with all due respect to mr cottle he was not there i was there and the court has broad discretion in determining what's an appropriate sanction this was not the broadest sanction that mr carroll says it was but it was certainly merited under the circumstances we started with the very beginning of the case re general refusing to obey the patten local rules and saying rather than bringing their claims down into elements for literal infringement they said it's all one element then for duck claim construction they decided to wait and see rather than coming out in the firm and typically saying with the claim terms meant they said it's plain meaning they waive privilege on the eve of the jones deposition they're ordered to produce documents they fail to produce those documents they withhold a critical conception reduction to practice document and refuse and claim it's privileged when it's not we get through to the eve of trial and again they waive privilege and it turns out that not only have they withheld a series of on their on their privilege log they've also withheld a series of documents that were within the scope of the court's earlier waiver order because they've withheld all sorts of documents that contradict testimony testimony of their choosing yes and under those circumstances the court didn't know was stuck she was in a place where what to do with this type of information and it was well within her discretion to drop this adverse confront because she concluded what was her only alternative if she decided to go in the alternative she decided to go forward what would that have come i think that to have gone forward as she states in her opinion would have required her to reopen discovery to allow documents to then be produced to order the production of all the wave documents and under the circumstances in her discretion she  rejection and a cope ending application the old one a patent was the issue fee had not yet been paid this is in the record that he was aware of the rejection and he may be affirmative decision not to references were mere draw the line is something to criticize that's why i asked for your definition of materiality if it's but for materiality that's really a different being alleged by what he was alleging it to the patent office because he was the prosecutor so he knows that they're saying that what's missing in the prior art is insertion at the end dodging th that's exactly what is taught in all four of these references so these aren't just a litany of references that may or may not be relevant these are but four are relevant and this is where there is mislead not invalidating references because these claims beyond the loss of the neuron anything else and we have been looking at this court for standards almost from the beginning because of the extraordinary potential for abuse so you put the lawyers on the defensive and it's two diversion and again i don't think anyone can ever find it can see which the issues can be raised and try to understand the strength of the argument here so in in this situation the district court found after hearing testimony from d davis which she found credible that these references had they've been disclosed to the patent office but they were known to the panel nervously even sudden related concerns they weren't necessarily known to the six am in there and since this was not a case where we were asserting we we invalidated the patent based on indefiniteness and the patent is certainly invalid for indefiniteness since it had there is absolutely no code pending applications after they filed their appeal brief that they received a noticeable ounce obviously that's not in the record but it's telling that they did not submit the claims that were issued in those cases because if the court and we would be happy to submit the claims because what the court's going to say is they don't look anything like claims one through five which they were but of which those references were but for material two they have all sorts of material that the district court's already decided that they're just that there but for material after the singing to six days of testimony curiam but not invalidated she determined that they would be invalidating because there but for material really was just to make those findings of fact the courts district courts already made the findings of fact that the references are but form material and her findings of fact are deference by this cour well conduct in there have a high standard for reasons that judge newman was explaining the consequences are grave to prosecutors to the p t o and to the company itself and that's wrong about specific intent this is not an adverse imprudence there's no finding of bad faith by by the lawyers here in this counsel the trial all together on one of the key elements on but for materiality four points the first is the most important i said this in my opening i said was that would talk about reverse comerica anti bodies so did longer and we were very clear on this that's in fact in the patent itself in the specification and then all through the p t o we have disclosed on burgundy the whole debate was in the already talking about antibiotic reversed comerica antibodies what's new about your invention or other point what she said these other references four of them i guess taken together say teach insertion into the locus but there are several problems with that citations to this we gave vent to the p t o there is nothing that is in these references that we hadn't already disclosed the p t o it's cumulative there could be a debate about whether or not our pattern was obvious we understand that but this is an equitable conduct that grave thing not the kind of you know more in my modest thing the second thing i don't think miss carson explains why these four references just taken on their own terms matter are brief explains lots of errors a dish it makes with respect to these thirteen makes very clear that that when we talked about reverse comerica mice we're talking about plain one and the citations are there thank you you think both sides of the case