bibtext: @InProceedings{ Hua_Memoryefficient_MICCAI2024,
                   author = { Huang, Kun and Ma, Xiao and Zhang, Yuhan and Su, Na and Yuan, Songtao and Liu, Yong and Chen, Qiang and Fu, Huazhu },
                   title = { { Memory-efficient High-resolution OCT Volume Synthesis with Cascaded Amortized Latent Diffusion Models } },
                   booktitle = {Medical Image Computing and Computer Assisted Intervention -- MICCAI 2024},
                   year = {2024},
                   publisher = {Springer Nature Switzerland},
                   volume = { LNCS 15007 },
                   month = {October},
                   pages = { pending },
                }
abstract: Optical coherence tomography (OCT) image analysis plays an important role in the field of ophthalmology. Current successful analysis models rely on available large datasets, which can be challenging to be obtained for certain tasks. The use of deep generative models to create realistic data emerges as a promising approach. However, due to limitations in hardware resources, it is still difficulty to synthesize high-resolution OCT volumes. In this paper, we introduce a cascaded amortized latent diffusion model (CA-LDM) that can synthesis high-resolution OCT volumes in a memory-efficient way. First, we propose non-holistic autoencoders to efficiently build a bidirectional mapping between high-resolution volume space and low-resolution latent space. In tandem with autoencoders, we propose cascaded diffusion processes to synthesize high-resolution OCT volumes with a global-to-local refinement process, amortizing the memory and computational demands. Experiments on a public high-resolution OCT dataset show that our synthetic data have realistic high-resolution and global features, surpassing the capabilities of existing methods. Moreover, performance gains on two down-stream fine-grained segmentation tasks demonstrate the benefit of the proposed method in training deep learning models for medical imaging tasks. The code is public available.
title: Memory-efficient High-resolution OCT Volume Synthesis with Cascaded Amortized Latent Diffusion Models
authors: Huang, Kun Ma, Xiao Zhang, Yuhan Su, Na Yuan, Songtao Liu, Yong Chen, Qiang Fu, Huazhu