bibtext: @InProceedings{ Zha_Whole_MICCAI2024,
                   author = { Zhang, Yundi and Chen, Chen and Shit, Suprosanna and Starck, Sophie and Rueckert, Daniel and Pan, Jiazhen },
                   title = { { Whole Heart 3D+T Representation Learning Through Sparse 2D Cardiac MR Images } },
                   booktitle = {Medical Image Computing and Computer Assisted Intervention -- MICCAI 2024},
                   year = {2024},
                   publisher = {Springer Nature Switzerland},
                   volume = { LNCS 15001 },
                   month = {October},
                   pages = { pending },
                }
abstract: Cardiac Magnetic Resonance (CMR) imaging serves as the gold-standard for evaluating cardiac morphology and function. Typically, a multi-view CMR stack, covering short-axis (SA) and 2/3/4-chamber long-axis (LA) views, is acquired for a thorough cardiac assessment. However, efficiently streamlining the complex, high-dimensional 3D+T CMR data and distilling compact, coherent representation remains a challenge. In this work, we introduce a whole-heart self-supervised learning framework that utilizes masked imaging modeling to automatically uncover the correlations between spatial and temporal patches throughout the cardiac stacks. This process facilitates the generation of meaningful and well-clustered heart representations without relying on the traditionally required, and often costly, labeled data. The learned heart representation can be directly used for various downstream tasks. Furthermore, our method demonstrates remarkable robustness, ensuring consistent representations even when certain CMR planes are missing/flawed. We train our model on 14,000 unlabeled CMR data from UK BioBank and evaluate it on 1,000 annotated data. The proposed method demonstrates superior performance to baselines in tasks that demand comprehensive 3D+T cardiac information, e.g. cardiac phenotype (ejection fraction and ventricle volume) prediction and multi-plane/multi-frame CMR segmentation, highlighting its effectiveness in extracting comprehensive cardiac features that are both anatomically and pathologically relevant. The code is available at https://github.com/Yundi-Zhang/WholeHeartRL.git.
title: Whole Heart 3D+T Representation Learning Through Sparse 2D Cardiac MR Images
authors: Zhang, Yundi Chen, Chen Shit, Suprosanna Starck, Sophie Rueckert, Daniel Pan, Jiazhen