bibtext: @InProceedings{ Bar_MARVEL_MICCAI2024,
                   author = { Barrier, Antoine and Coudert, Thomas and Delphin, Aurélien and Lemasson, Benjamin and Christen, Thomas },
                   title = { { MARVEL: MR Fingerprinting with Additional micRoVascular Estimates using bidirectional LSTMs } },
                   booktitle = {Medical Image Computing and Computer Assisted Intervention -- MICCAI 2024},
                   year = {2024},
                   publisher = {Springer Nature Switzerland},
                   volume = { LNCS 15002 },
                   month = {October},
                   pages = { pending },
                }
abstract: The Magnetic Resonance Fingerprinting (MRF) approach aims to estimate multiple MR or physiological parameters simultaneously with a single fast acquisition sequence. Most of the MRF studies proposed so far have used simple MR sequence types to measure relaxation times (T1, T2). In that case, deep learning algorithms have been successfully used to speed up the reconstruction process. In theory, the MRF concept could be used with a variety of other MR sequence types and should be able to provide more information about the tissue microstructures. Yet, increasing the complexity of the numerical models often leads to prohibited simulation times, and estimating multiple parameters from one sequence implies new dictionary dimensions whose sizes become too large for standard computers and DL architectures.
  In this paper, we propose to analyze the MRF signal coming from a complex balanced Steady-State Free Precession (bSSFP) type sequence to simultaneously estimate relaxometry maps (T1, T2), Field maps (B1, B0) as well as microvascular properties such as the local Cerebral Blood Volume (CBV) or the averaged vessel Radius (R).
  To bypass the curse of dimensionality, we propose an efficient way to simulate the MR signal coming from numerical voxels containing realistic microvascular networks as well as a Bidirectional Long Short-Term Memory network that replaces the matching process.
  On top of standard MRF maps, our results on 3 human volunteers suggest that our approach can quickly produce high-quality quantitative maps of microvascular parameters that are otherwise obtained using longer dedicated sequences and intravenous injection of a contrast agent. This approach could be used for the management of multiple pathologies and could be tuned to provide other types of microstructural information.
title: MARVEL: MR Fingerprinting with Additional micRoVascular Estimates using bidirectional LSTMs
authors: Barrier, Antoine Coudert, Thomas Delphin, Aurélien Lemasson, Benjamin Christen, Thomas