User: Do you think depression ran in Wittgenstein's family?
Assistant: Depression is a mental health issue which can sometimes lead to suicide. It is known to run in families. Ludwig Wittgenstein personally experienced at least one period of severe depression and three of his four older brothers died by separate acts of suicide. Based on the fact that so many of Wittgenstein's immediate family members experienced depression or died by suicide, I think it is fair to say depression ran in Wittgenstein's family.