Hypopigmentation kan jedhamu kuni dhabamu qalamu goggaat. Kuni immo kan ta'uu dhumachuu melanocyte irra kan ka'uu yoo ta'u, kunis amino acidiin tyrosine jedhamu yoo diqqattu, melanocytiin waan amino acidii kana fayyadame melanin midhasuuf, melanocytileen diqachuu jalqaba.

Muudanatti aanee kan baalii fudhate Gadaa kiilolee ti. Bara Gadaa Kiilolee keessa Habashoonni gargaarsa warra Poorchugaalin, Imaam Ahimadiin bara 1543 waan ajjeesaniif qalbii tokkoon Oromorratti xiyyeefatanii meeshaa ammayyaa fi human waraanaa Awuroopparraa argataniin gargaaramuudhan Oromoo irratti duulani. Mootichi Habashaa Galaawudoos Imaam Ahimadiin erga ajjeese booda, waraana guddaa nama Adaal Mabiiraq jedhanuun hoogganamu gara Oromootti bobbaase. Gadaan Kiilolee waraana Habashaa fi Faranjii meeshaa hammayyaa akka madfii hidhate kana bara 1545 ofirraa rukutee, ajajaa waraanaa ari'ee laga Awwash ceesise. Waraani habashaa hedduun harka Gadaa Kiiloleetti baqee dhume jedhe Abbaan Baahire. Humnoota Habashaa fi Faranjii meeshaa hammayyaatti gargaaramanu waan mo’eef, Gadaa dhugaa lole, kan Lole jedhamee seenaa keessati yaadatama. Jechi ""kan lole"" jedhu kun bara dheerina keesa ""Kiilolee"" jedhamuun beekkama.

Kuttalle nucleus bekkamo ta’an nuclear envelope fi nuclear lamina dha. Nuclear envelopen membrane daballata (membrane lama) kan organelleotta hunda ofii kessatti marsee, wantotta nucleus kessatti argaman kan cytoplasm irra gargar bassu dha. Nuclear laminan immo waan walitti xaxame yoo ta’u jabbena akkumma cytoskeleton celli kennu innillen nucleus kenna. Nuclear membranen moleculotta bayye waan hin dabarsineef (impermeable membrane waan ta’ef) demma moleculotta nucleus fi cytoplasma jiddu akka jirrattu urran nucleus (nuclear pore)n jirrachun barbachisaa. Urrotni kuni membreni lachu kessa waan dabranif akka dandii moleculotta diddiqo fi ionotta ta’e tajajilla gudda kenna. Demma moleculotta guggudo akka protein jirran geggesuf egganoon kan godhamu yoo ta’u, active transportiin carrier proteiniin geggefamu jirrachu qaba. Nuclear transportiin hojja cellif bayye barbachisaa dha, kunis sababa demman urra kessani godhamu “gene expression” fi “chromosomal maintenance”ii waan qarqaruf.