Definition: Translate the given Spanish text to English

Positive Example 1 -
Input: A method for converting a series of m-bit information words to a modulated signal is described.
Output: Se describe un método para convertir una serie de palabras de informacion de bits m a una señal modulada.

Positive Example 2 -
Input: A last plastic cover is applied as a final protection.
Output: La presente invencion comprende un nuevo mezclador termocinetico.

Negative Example 1 -
Input: Luminescent optical sensor.
Output: SENSOR OPTICO LUMINISCENTE.

Negative Example 2 -
Input: The urinal is similar to a common toilet.
Output: El común es similar a un inodoro orinal.

Now complete the following example -
Input: The present invention relates to an ICOS binding protein or antigen binding portion thereof that is an agonist to human ICOS and does not induce complement, ADCC, or CDC when placed in contact with a T cell in vivo and methods of treating cancer, infectious disease and/or sepsis with said ICOS binding protein or antigen binding portion thereof.
Output: La presente invención se refiere a una proteína de unión a ICOS o porción de unión al antígeno de la misma que es un agonista para ICOS humana y no induce complemento, ADCC o CDC cuando se pone en contacto con un linfocito T in vivo.