Definition: Translate the given Spanish text to English

Positive Example 1 -
Input: A method for converting a series of m-bit information words to a modulated signal is described.
Output: Se describe un método para convertir una serie de palabras de informacion de bits m a una señal modulada.

Positive Example 2 -
Input: A last plastic cover is applied as a final protection.
Output: La presente invencion comprende un nuevo mezclador termocinetico.

Negative Example 1 -
Input: Luminescent optical sensor.
Output: SENSOR OPTICO LUMINISCENTE.

Negative Example 2 -
Input: The urinal is similar to a common toilet.
Output: El común es similar a un inodoro orinal.

Now complete the following example -
Input: Methods of making the compounds, and their use as therapeutic agents, for example, in treating cancer and other diseases characterized by defects in DNA replication, chromosome segregation, or cell division also are disclosed.
Output: Tambien se describen metodos para elaborar los compuestos, y su uso como agentes terapeuticos, por ejemplo, en el tratamiento de cancer y otras enfermedades caracterizadas por defectos en la replicacion del ADN, segregacion cromosomica, o division celular.