LiteFold/PDB huggingface dataset:
PDB entry 7kww: X-ray Crystal Structure of PlyCB Mutant K59H
Classification: ANTIMICROBIAL PROTEIN
Source organism: Streptococcus virus C1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2020-12-02
Authors: Williams, D.E., Broendum, S.S., Hayes, B.K., Drinkwater, N., McGowan, S.
PDB entry 7kwx: Spermidine N-acetyltransferase SpeG N152L mutant from Vibrio cholerae
Classification: TRANSFERASE
Source organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.42 Å
Deposited: 2020-12-02
Authors: Le, V.T.B., Tsimbalyuk, S., Lim, E.Q., Solis, A., Gawat, D., Boeck, P., Renolo, R., Forwood, J.K., Kuhn, M.L.
PDB entry 7kwy: X-ray Crystal Structure of PlyCB Mutant R66K
Classification: ANTIMICROBIAL PROTEIN
Source organism: Streptococcus virus C1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2020-12-02
Authors: Williams, D.E., Broendum, S.S., Hayes, B.K., Drinkwater, N., McGowan, S.
PDB entry 7kwz: TDP-43 LCD amyloid fibrils
Classification: PROTEIN FIBRIL
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.2 Å
Deposited: 2020-12-02
Authors: Li, Q., Babinchak, W.M., Surewicz, W.K.
PDB entry 7kx0: Crystal structure of the CD27:CD70 co-stimulatory complex
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.69 Å
Deposited: 2020-12-02
Authors: Maben, Z., Liu, W., Mosyak, L., Chaparro-Riggers, J.
PDB entry 7kx1: Dihydrodipicolinate synthase (DHDPS) from C.jejuni, Y110F mutant with pyruvate bound in the active in C2221 space group
Classification: LYASE
Source organism: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.04 Å
Deposited: 2020-12-02
Authors: Saran, S., Sanders, D.A.R.
PDB entry 7kx2: Spermidine N-acetyltransferase SpeG F149A mutant from Vibrio cholerae
Classification: TRANSFERASE
Source organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2020-12-03
Authors: Le, V.T.B., Tsimbalyuk, S., Lim, E.Q., Solis, A., Gawat, D., Boeck, P., Renolo, R., Forwood, J.K., Kuhn, M.L.
PDB entry 7kx3: SpeG Spermidine N-acetyltransferase F149G mutant from Vibrio cholerae
Classification: TRANSFERASE
Source organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.67 Å
Deposited: 2020-12-03
Authors: Le, V.T.B., Tsimbalyuk, S., Lim, E.Q., Solis, A., Gawat, D., Boeck, P., Renolo, R., Forwood, J.K., Kuhn, M.L.
PDB entry 7kx4: Anti-CCHFV ADI-36121 Fab
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2020-12-03
Authors: Mishra, A.K., McLellan, J.S.
PDB entry 7kx5: Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with noncovalent inhibitor Jun8-76-3A
Classification: VIRAL PROTEIN
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2020-12-03
Authors: Sacco, M., Wang, J., Chen, Y.
PDB entry 7kx6: Crystal structure of DCLK1-KD in complex with XMD8-85
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2020-12-03
Authors: Patel, O., Lucet, I.
PDB entry 7kx7: Cryo-EM structure of Ephydatia fluviatilis PiwiA-piRNA complex
Classification: HYDROLASE,RNA BINDING PROTEIN/RNA
Source organism: Ephydatia fluviatilis; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.8 Å
Deposited: 2020-12-03
Authors: Anzelon, T.A., Chowdhury, S., Lander, G.C., MacRae, I.J.
PDB entry 7kx8: Crystal structure of DCLK1-Cter in complex with FMF-03-055-1
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1 Å
Deposited: 2020-12-03
Authors: Patel, O., Lucet, I.
PDB entry 7kx9: Cryo-EM structure of Ephydatia fluviatilis PiwiA-piRNA-target complex
Classification: HYDROLASE,RNA BINDING PROTEIN/RNA
Source organism: Ephydatia fluviatilis; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.5 Å
Deposited: 2020-12-03
Authors: Anzelon, T.A., Chowdhury, S., Lander, G.C., MacRae, I.J.
PDB entry 7kxa: Crystal structure of Enoyl-[acyl-carrier-protein] reductase [NADH] (InhA) from Mycobacterium kansasii in complex with NAD
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium kansasii
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2020-12-03
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 7kxb: Crystal structure of SARS-CoV-2 Nsp3 Macrodomain complex with PARG329
Classification: HYDROLASE
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2020-12-03
Authors: Arvai, A., Brosey, C.A., Bommagani, S., Link, T., Jones, D.E., Ahmed, Z., Tainer, J.A.
PDB entry 7kxc: The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, sodium ion at the metal coordination site and benzimidazole (BZI) at the enzyme beta-site at 1.30 Angstrom resolution. One of the beta-Q114 rotamer conformations allows a hydrogen bond to form with the PLP oxygen at the position 3 in the ring
Classification: LYASE/LYASE INHIBITOR
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Experimental method: X-RAY DIFFRACTION
Resolution: 1.51 Å
Deposited: 2020-12-03
Authors: Hilario, E., Dunn, M.F., Mueller, L.J.
PDB entry 7kxd: CRYSTAL STRUCTURE OF RAR-RELATED ORPHAN RECEPTOR C (NHIS-RORGT(244-487)-L6-SRC1(678-692)) IN COMPLEX WITH {3,5-DICHLORO-4-[4-METHOXY-3-(PROPAN-2-YL)PHENOXY]PHENYL}METHANOL
Classification: TRANSFERASE/Agonist
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.624 Å
Deposited: 2020-12-03
Authors: Sack, J.
PDB entry 7kxe: CRYSTAL STRUCTURE OF RAR-RELATED ORPHAN RECEPTOR C (NHIS-RORGT(244-487)-L6-SRC1(678-692)) IN COMPLEX WITH {3,5-DICHLORO-4-[4-METHOXY-3-(PROPAN-2-YL)PHENOXY]PHENYL}METHANOL
Classification: TRANSFERASE/Agonist
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.42 Å
Deposited: 2020-12-03
Authors: Sack, J.
PDB entry 7kxf: CRYSTAL STRUCTURE OF RAR-RELATED ORPHAN RECEPTOR C (NHIS-RORGT(244-487)-L6-SRC1(678-692)) IN COMPLEX WITH {3,5-DICHLORO-4-[4-METHOXY-3-(PROPAN-2-YL)PHENOXY]PHENYL}METHANOL
Classification: TRANSFERASE/Agonist
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.141 Å
Deposited: 2020-12-03
Authors: Sack, J.
PDB entry 7kxg: Dihydrodipicolinate synthase (DHDPS) from C.jejuni with pyruvate bound in the active site and L-histidine bound at the allosteric site
Classification: LYASE
Source organism: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.28 Å
Deposited: 2020-12-03
Authors: Saran, S., Sanders, D.A.R.
PDB entry 7kxh: Dihydrodipicolinate synthase (DHDPS) from C.jejuni with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site in C2221 space group
Classification: LYASE
Source organism: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.94 Å
Deposited: 2020-12-03
Authors: Saran, S., Sanders, D.A.R.
PDB entry 7kxi: Structure of XL5-ligated hRpn13 Pru domain
Classification: PROTEIN BINDING
Source organism: Homo sapiens
Experimental method: SOLUTION NMR
Deposited: 2020-12-03
Authors: Lu, X., Walters, K.J.
PDB entry 7kxj: SARS-CoV-2 spike protein in complex with Fab 15033-7, 3-""up"", asymmetric
Classification: VIRAL PROTEIN/Immune System
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 6.4 Å
Deposited: 2020-12-04
Authors: Li, Z., Rini, J.
PDB entry 7kxk: SARS-CoV-2 spike protein in complex with Fab 15033-7, 2-""up""-1-""down"" conformation
Classification: VIRAL PROTEIN/Immune System
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 5 Å
Deposited: 2020-12-04
Authors: Li, Z., Rini, J.
PDB entry 7kxl: BTK1 SOAKED WITH COMPOUND 5, Y551 IS SEQUESTERED
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.84 Å
Deposited: 2020-12-04
Authors: Gardberg, A.
PDB entry 7kxm: BTK1 SOAKED WITH COMPOUND 5, Y551 IS SEQUESTERED
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.33 Å
Deposited: 2020-12-04
Authors: Gardberg, A.
PDB entry 7kxn: BTK1 SOAKED WITH COMPOUND 26
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.34 Å
Deposited: 2020-12-04
Authors: Viacava Follis, A.
PDB entry 7kxo: BTK1 SOAKED WITH COMPOUND 24
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.94 Å
Deposited: 2020-12-04
Authors: Viacava Follis, A.
PDB entry 7kxp: BTK1 SOAKED WITH COMPOUND 25
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.83 Å
Deposited: 2020-12-04
Authors: Viacava Follis, A.
PDB entry 7kxq: BTK1 SOAKED WITH COMPOUND 30
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.38 Å
Deposited: 2020-12-04
Authors: Viacava Follis, A.
PDB entry 7kxr: Protective antigen pore translocating lethal factor N-terminal domain
Classification: TOXIN
Source organism: Bacillus anthracis
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.3 Å
Deposited: 2020-12-04
Authors: Machen, A.J., Freudenthal, B.D.
PDB entry 7kxs: Computational design of constitutively active cGAS
Classification: DE NOVO PROTEIN
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2020-12-04
Authors: Dowling, Q., Volkman, H.E., Gray, E.E., Ovchinnikov, S., Cambier, S., Bera, A.K., Bick, M., Kang, A., Stetson, D.B., King, N.P.
PDB entry 7kxt: Crystal structure of human EED
Classification: GENE REGULATION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2020-12-04
Authors: Zhu, L., Dong, A., Du, D., Liu, Y., Luo, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
PDB entry 7kxw: Crystal structure of DCLK1-KD in complex with DCLK1-IN-1
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.002 Å
Deposited: 2020-12-05
Authors: Patel, O., Lucet, I.
PDB entry 7kxy: Cryo-EM structure of human Factor Va at 4.4 Angstrom resolution
Classification: BLOOD CLOTTING
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.4 Å
Deposited: 2020-12-05
Authors: Ruben, E.A., Di Cera, E.
PDB entry 7kxz: Active conformation of EGFR kinase in complex with BI-4020
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2020-12-06
Authors: Beyett, T.S., Eck, M.J.
PDB entry 7ky0: Inactive conformation of EGFR (T790M/V948R) kinase in complex with BI-4020
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1 Å
Deposited: 2020-12-06
Authors: Beyett, T.S., Eck, M.J.
PDB entry 7ky1: Molecular basis for control of antibiotic production by a bacterial hormones
Classification: ANTIBIOTIC
Source organism: Streptomyces coelicolor
Experimental method: X-RAY DIFFRACTION
Resolution: 1.50003 Å
Deposited: 2020-12-06
Authors: Bhukya, H., Fulop, V.
PDB entry 7ky2: Botulism Neurooxin Light Chain A app form
Classification: TOXIN
Source organism: Clostridium botulinum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.78 Å
Deposited: 2020-12-07
Authors: Ortega, M.E., Salazameda, N.T.
PDB entry 7ky5: Structure of the S. cerevisiae phosphatidylcholine flippase Dnf2-Lem3 complex in the E2P transition state
Classification: TRANSLOCASE
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.98 Å
Deposited: 2020-12-07
Authors: Bai, L., You, Q., Jain, B.K., Duan, H.D., Kovach, A., Graham, T.R., Li, H.
PDB entry 7ky6: Structure of the S. cerevisiae phosphatidylcholine flippase Dnf1-Lem3 complex in the apo E1 state
Classification: TRANSLOCASE
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.1 Å
Deposited: 2020-12-07
Authors: Bai, L., You, Q., Jain, B.K., Duan, H.D., Kovach, A., Graham, T.R., Li, H.
PDB entry 7ky7: Structure of the S. cerevisiae phosphatidylcholine flippase Dnf2-Lem3 complex in the apo E1 state
Classification: TRANSLOCASE
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.08 Å
Deposited: 2020-12-07
Authors: Bai, L., You, Q., Jain, B.K., Duan, H.D., Kovach, A., Graham, T.R., Li, H.
PDB entry 7ky8: Structure of the S. cerevisiae phosphatidylcholine flippase Dnf2-Lem3 complex in the E1-ATP state
Classification: TRANSLOCASE
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.85 Å
Deposited: 2020-12-07
Authors: Bai, L., You, Q., Jain, B.K., Duan, H.D., Kovach, A., Graham, T.R., Li, H.
PDB entry 7ky9: Structure of the S. cerevisiae phosphatidylcholine flippase Dnf2-Lem3 complex in the E1-ADP state
Classification: TRANSLOCASE
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.05 Å
Deposited: 2020-12-07
Authors: Bai, L., You, Q., Jain, B.K., Duan, H.D., Kovach, A., Graham, T.R., Li, H.
PDB entry 7kya: Structure of the S. cerevisiae phosphatidylcholine flippase Dnf2-Lem3 complex in the E2P state
Classification: TRANSLOCASE
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.5 Å
Deposited: 2020-12-07
Authors: Bai, L., You, Q., Jain, B.K., Duan, H.D., Kovach, A., Graham, T.R., Li, H.
PDB entry 7kyb: Structure of the S. cerevisiae phosphatidylcholine flippase Dnf1-Lem3 complex in the E1-ADP state
Classification: TRANSLOCASE
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.2 Å
Deposited: 2020-12-07
Authors: Bai, L., You, Q., Jain, B.K., Duan, H.D., Kovach, A., Graham, T.R., Li, H.
PDB entry 7kyc: Structure of the S. cerevisiae phosphatidylcholine flippase Dnf1-Lem3 complex in the E2P state
Classification: TRANSLOCASE
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.8 Å
Deposited: 2020-12-07
Authors: Bai, L., You, Q., Jain, B.K., Duan, H.D., Kovach, A., Graham, T.R., Li, H.
PDB entry 7kyd: Drosophila melanogaster long-chain fatty-acyl-CoA synthetase CG6178
Classification: LIGASE
Source organism: Drosophila melanogaster
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2020-12-07
Authors: Adams, S.T., Zephyr, J., Bohn, M.F., Schiffer, C.A., Miller, S.C.
PDB entry 7kye: Structure of a GNAT superfamily PA3944 acetyltransferase in complex with CHES
Classification: TRANSFERASE
Source organism: Pseudomonas aeruginosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.93 Å
Deposited: 2020-12-07
Authors: Czub, M.P., Porebski, P.J., Cymborowski, M., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 7kyf: Botulism Neurooxin Light Chain A app form
Classification: TOXIN
Source organism: Clostridium botulinum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.33 Å
Deposited: 2020-12-07
Authors: Ortega, M.E., Salzameda, N.T.
PDB entry 7kyh: Botulism Neurooxin Light Chain A app form
Classification: TOXIN
Source organism: Clostridium botulinum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.91 Å
Deposited: 2020-12-07
Authors: Ortega, M.E., Salzameda, N.T.
PDB entry 7kyj: Structure of a GNAT superfamily PA3944 acetyltransferase in complex with zinc
Classification: TRANSFERASE
Source organism: Pseudomonas aeruginosa
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2020-12-07
Authors: Czub, M.P., Porebski, P.J., Cymborowski, M., Shabalin, I.G., Reidl, C.T., Becker, D.P., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 7kyk: Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM589 (ethyl 3-methyl-4-((4-(trifluoromethyl)benzo[d]oxazol-7-yl)methyl)-1H-pyrrole-2-carboxylate)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Plasmodium falciparum (isolate 3D7)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2020-12-08
Authors: Deng, X., Phillips, M., Tomchick, D.
PDB entry 7kyl: Powassan virus Envelope protein DIII in complex with neutralizing Fab POWV-80
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Mus musculus; Powassan virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2020-12-08
Authors: Errico, J.M., Nelson, C.A., Fremont, D.H., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 7kym: Crystal structure of the MarR family transcriptional regulator from Bradyrhizobium japonicum
Classification: DNA BINDING PROTEIN
Source organism: Bradyrhizobium japonicum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2020-12-08
Authors: Walton, W.G., Redinbo, M.R., Dangl, J.L.
PDB entry 7kyo: PsaBC from Streptococcus pneumoniae in complex with Fab
Classification: TRANSPORT PROTEIN/IMMUNE SYSTEM
Source organism: Mus musculus; Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.85 Å
Deposited: 2020-12-08
Authors: Maher, M.J., Sjohamn, J.
PDB entry 7kyp: PsaBC from Streptococcus pneumoniae in complex with Fab
Classification: TRANSPORT PROTEIN
Source organism: Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2020-12-08
Authors: Maher, M.J., Sjohamn, J.
PDB entry 7kyq: Crystal structure of human BCCIP beta (Native1)
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.06 Å
Deposited: 2020-12-08
Authors: Choi, W.S., Liu, B., Shen, Z., Yang, W.
PDB entry 7kyr: Crystal structure of I107E CuB myoglobin (I107E L29H F43H sperm whale myoglobin)
Classification: OXYGEN TRANSPORT
Source organism: Physeter catodon
Experimental method: X-RAY DIFFRACTION
Resolution: 1.71 Å
Deposited: 2020-12-08
Authors: Petrik, I., Lu, Y.
PDB entry 7kys: Crystal structure of human BCCIP beta (Native2)
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2020-12-08
Authors: Choi, W.S., Liu, B., Shen, Z., Yang, W.
PDB entry 7kyt: The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site and benzimidazole (BZI) at the enzyme beta-site at 1.35 Angstrom resolution
Classification: LYASE/LYASE INHIBITOR
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Experimental method: X-RAY DIFFRACTION
Resolution: 1.35 Å
Deposited: 2020-12-08
Authors: Hilario, E., Dunn, M.F., Mueller, L.J.
PDB entry 7kyu: The crystal structure of SARS-CoV-2 Main Protease with the formation of Cys145-1H-indole-5-carboxylate
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 1.48 Å
Deposited: 2020-12-08
Authors: Tan, K., Maltseva, N.I., Jedrzejczak, R.P., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 7kyv: Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM634 (3-methyl-N-(1-(5-methylisoxazol-3-yl)ethyl)-4-(4-(trifluoromethyl)benzyl)-1H-pyrrole-2-carboxamide)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Plasmodium falciparum (isolate 3D7)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2020-12-08
Authors: Deng, X., Phillips, M., Tomchick, D.
PDB entry 7kyw: Crystal structure of timothy grass allergen Phl p 12.0101 reveals an unusual profilin dimer
Classification: ALLERGEN
Source organism: Phleum pratense
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2020-12-09
Authors: O'Malley, A., Kapingidza, A.B., Hyduke, N., Dolamore, C., Chruszcz, M.
PDB entry 7kyx: Crystal structure of human CORO6
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.63 Å
Deposited: 2020-12-09
Authors: Zeng, H., Dong, A., Loppnau, P., Hutchinson, A., Seitova, A., Arrowsmith, C.H., Edwards, A.M., Halabelian, L., Structural Genomics Consortium (SGC)
PDB entry 7kyy: Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM697 (3-methyl-N-(1-(5-methylisoxazol-3-yl)ethyl)-4-(6-(trifluoromethyl)-1H-indol-3-yl)-1H-pyrrole-2-carboxamide)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Plasmodium falciparum (isolate 3D7)
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2020-12-09
Authors: Deng, X., Phillips, M., Tomchick, D.
PDB entry 7kyz: Solution structures of full-length K-RAS bound to GDP
Classification: CELL CYCLE
Source organism: Homo sapiens
Experimental method: SOLUTION NMR
Deposited: 2020-12-09
Authors: Sharma, A.K., Maciag, A.E.
PDB entry 7kz0: Human MBD4 glycosylase domain bound to DNA containing substrate analog 2'-deoxy-pseudouridine
Classification: HYDROLASE/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.57 Å
Deposited: 2020-12-09
Authors: Pidugu, L.S., Pozharski, E., Drohat, A.C.
PDB entry 7kz1: Human MBD4 glycosylase domain bound to DNA containing an abasic site
Classification: HYDROLASE/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.62 Å
Deposited: 2020-12-09
Authors: Pidugu, L.S., Bright, H., Pozharski, E., Drohat, A.C.
PDB entry 7kz2: Dihydrodipicolinate synthase (DHDPS) from C.jejuni, Y110F mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site in C2221 space group
Classification: LYASE
Source organism: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2020-12-09
Authors: Saran, S., Sanders, D.A.R.
PDB entry 7kz3: Crystal structure of KabA from Bacillus cereus UW85 in complex with the internal aldimine
Classification: BIOSYNTHETIC PROTEIN, TRANSFERASE
Source organism: Bacillus cereus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2020-12-09
Authors: Prasertanan, T., Palmer, D.R.J., Sanders, D.A.R.
PDB entry 7kz4: Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM705 (N-(1-(1H-1,2,4-triazol-3-yl)ethyl)-3-methyl-4-(1-(6-(trifluoromethyl)pyridin-3-yl)cyclopropyl)-1H-pyrrole-2-carboxamide)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Plasmodium falciparum (isolate 3D7)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2020-12-09
Authors: Deng, X., Phillips, M., Tomchick, D.
PDB entry 7kz5: Crystal structure of KabA from Bacillus cereus UW85 in complex with the plp external aldimine adduct with kanosamine-6-phosphate
Classification: BIOSYNTHETIC PROTEIN, TRANSFERASE
Source organism: Bacillus cereus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2020-12-10
Authors: Prasertanan, T., Palmer, D.R.J., Sanders, D.A.R.
PDB entry 7kz6: Crystal structure of KabA from Bacillus cereus UW85 with bound cofactor PMP
Classification: BIOSYNTHETIC PROTEIN, TRANSFERASE
Source organism: Bacillus cereus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2020-12-10
Authors: Prasertanan, T., Palmer, D.R.J., Sanders, D.A.R.
PDB entry 7kz7: Crystals Structure of the Mutated Protease Domain of Botulinum Neurotoxin X (X4130B1).
Classification: TOXIN
Source organism: Clostridium botulinum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2020-12-10
Authors: Blum, T.R., Liu, H., Packer, M.S., Xiong, X., Lee, P.G., Zhang, S., Richter, M., Minasov, G., Satchell, K.J.F., Dong, M., Liu, D.R., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 7kz8: Crystal structure of substrate-binding protein Aapf from Pseudomonas sp. PDC86
Classification: TRANSPORT PROTEIN
Source organism: Pseudomonas sp. PDC86
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2020-12-10
Authors: Luo, S., Dadhwal, P., Tong, L.
PDB entry 7kz9: Crystal structure of Pseudomonas sp. PDC86 substrate-binding protein Aapf in complex with a signaling molecule HEHEAA
Classification: TRANSPORT PROTEIN
Source organism: Pseudomonas sp. PDC86
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2020-12-10
Authors: Luo, S., Dadhwal, P., Tong, L.
PDB entry 7kza: Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1antibodies
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.69 Å
Deposited: 2020-12-10
Authors: Langley, D.B., Christ, D.
PDB entry 7kzb: Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1antibodies
Classification: VIRAL PROTEIN/Immune System
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 2.83 Å
Deposited: 2020-12-10
Authors: Langley, D.B., Christ, D.
PDB entry 7kzc: Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1antibodies
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2020-12-10
Authors: Langley, D.B., Christ, D.
PDB entry 7kzd: Crystal structure of KabA from Bacillus cereus UW85 in complex with the reduced internal aldimine and with bound Glutarate
Classification: BIOSYNTHETIC PROTEIN, TRANSFERASE
Source organism: Bacillus cereus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2020-12-10
Authors: Prasertanan, T., Palmer, D.R.J., Sanders, D.A.R.
PDB entry 7kze: Substrate-dependent divergence of leukotriene A4 hydrolase aminopeptidase activity
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2020-12-10
Authors: Lee, K.H., Shim, Y., Paige, M., Noble, S.M.
PDB entry 7kzf: High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility
Classification: VIRUS
Source organism: Human papillomavirus type 16
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.1 Å
Deposited: 2020-12-10
Authors: Hartmann, S.R., Goetschius, D.J., Hafenstein, S.
PDB entry 7kzg: Human MBD4 glycosylase domain bound to DNA containing oxacarbenium-ion analog 1-aza-2'-deoxyribose
Classification: HYDROLASE/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.68 Å
Deposited: 2020-12-10
Authors: Pidugu, L.S., Pozharski, E., Drohat, A.C.
PDB entry 7kzh: Zinc finger antiviral protein (ZAP) central domain
Classification: ANTIVIRAL PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.49 Å
Deposited: 2020-12-10
Authors: Pornillos, O.P.
PDB entry 7kzi: Intermediate state (QQQ) of near full-length DnaK alternatively fused with a substrate peptide
Classification: CHAPERONE
Source organism: Escherichia coli (strain K12); Escherichia coli K-12
Experimental method: X-RAY DIFFRACTION
Resolution: 2.82 Å
Deposited: 2020-12-10
Authors: Wang, W., Hendrickson, W.A.
PDB entry 7kzl: Cyclopentane peptide nucleic acid in complex with DNA
Classification: PEPTIDE NUCLEIC ACID/DNA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.3 Å
Deposited: 2020-12-10
Authors: Botos, I., Appella, D.H.
PDB entry 7kzm: Outer dynein arm bound to doublet microtubules from C. reinhardtii
Classification: MOTOR PROTEIN
Source organism: Chlamydomonas reinhardtii
Experimental method: ELECTRON MICROSCOPY
Resolution: 7.5 Å
Deposited: 2020-12-10
Authors: Walton, T., Wu, H., Brown, A.B.
PDB entry 7kzn: Outer dynein arm core subcomplex from C. reinhardtii
Classification: MOTOR PROTEIN
Source organism: Chlamydomonas reinhardtii
Experimental method: ELECTRON MICROSCOPY
Resolution: 4 Å
Deposited: 2020-12-10
Authors: Walton, T., Wu, H., Brown, A.B.
PDB entry 7kzo: Outer dynein arm docking complex bound to doublet microtubules from C. reinhardtii
Classification: MOTOR PROTEIN
Source organism: Chlamydomonas reinhardtii
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.3 Å
Deposited: 2020-12-10
Authors: Walton, T., Wu, H., Brown, A.B.
PDB entry 7kzp: Structure of the human Fanconi anaemia Core complex
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.1 Å
Deposited: 2020-12-10
Authors: Wang, S.L., Pavletich, N.P.
PDB entry 7kzq: Structure of the human Fanconi anaemia Core-ID complex
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.3 Å
Deposited: 2020-12-10
Authors: Wang, S.L., Pavletich, N.P.
PDB entry 7kzr: Structure of the human Fanconi Anaemia Core-UBE2T-ID complex
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.4 Å
Deposited: 2020-12-10
Authors: Wang, S.L., Pavletich, N.P.
PDB entry 7kzs: Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in open state
Classification: LIGASE/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.2 Å
Deposited: 2020-12-10
Authors: Wang, S.L., Pavletich, N.P.
PDB entry 7kzt: Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in intermediate state
Classification: LIGASE/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.2 Å
Deposited: 2020-12-10
Authors: Wang, S.L., Pavletich, N.P.
PDB entry 7kzu: Quasi-intermediate state (Q) of a truncated Hsp70 DnaK fused with a substrate peptide
Classification: CHAPERONE
Source organism: Escherichia coli (strain K12); Escherichia coli K-12
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2020-12-10
Authors: Wang, W., Hendrickson, W.A.
PDB entry 7kzv: Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in closed state
Classification: LIGASE/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.2 Å
Deposited: 2020-12-10
Authors: Wang, S.L., Pavletich, N.P.
PDB entry 7kzw: Crystal structure of FTT_1639c from Francisella tularensis str. tularensis SCHU S4
Classification: UNKNOWN FUNCTION
Source organism: Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.34 Å
Deposited: 2020-12-10
Authors: Stogios, P.J., Skarina, T., Osipiuk, J., Di Leo, R., Savchenko, A., Joachimiak, A., Satchell, K.J.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 7kzx: Cryo-EM structure of YiiP-Fab complex in Apo state
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens; Shewanella oneidensis
Experimental method: ELECTRON MICROSCOPY
Resolution: 4 Å
Deposited: 2020-12-10
Authors: Lopez-Redondo, M.L., Fan, S., Koide, A., Koide, S., Beckstein, O., Stokes, D.L.
PDB entry 7kzy: Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM778 (3-methyl-N-(1-(5-methyl-1H-pyrazol-3-yl)ethyl)-4-(1-(6-(trifluoromethyl)pyridin-3-yl)cyclopropyl)-1H-pyrrole-2-carboxamide)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Plasmodium falciparum (isolate 3D7)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2020-12-10
Authors: Deng, X., Phillips, M., Tomchick, D.
PDB entry 7kzz: Cryo-EM structure of YiiP-Fab complex in Holo state
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens; Shewanella oneidensis
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.42 Å
Deposited: 2020-12-10
Authors: Lopez-Redondo, M.L., Fan, S., Koide, A., Koide, S., Beckstein, O., Stokes, D.L.
PDB entry 7l00: Crystal Structure of C. difficile Enoyl-Acyl Carrier Protein Reductase (FabK) in Complex with an Inhibitor
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Clostridioides difficile
Experimental method: X-RAY DIFFRACTION
Resolution: 1.72 Å
Deposited: 2020-12-10
Authors: Akhtar, A., Santarsiero, B.D., Hevener, K.E.
PDB entry 7l01: Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM782 (N-(1-(5-cyano-1H-pyrazol-3-yl)ethyl)-3-methyl-4-(1-(6-(trifluoromethyl)pyridin-3-yl)cyclopropyl)-1H-pyrrole-2-carboxamide)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Plasmodium falciparum (isolate 3D7)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2020-12-10
Authors: Deng, X., Phillips, M., Tomchick, D.
PDB entry 7l02: Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound to one copy of domain-swapped antibody 2G12
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.2 Å
Deposited: 2020-12-10
Authors: Manne, K., Henderson, R., Acharya, P.
PDB entry 7l03: The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and sodium ion at the metal coordination site at 1.60 Angstrom resolution. Three water molecules are close to the amynoacrylate at the enzyme beta-site
Classification: LYASE/LYASE INHIBITOR
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2020-12-11
Authors: Hilario, E., Dunn, M.F., Mueller, L.J.
PDB entry 7l04: Crystal Structure of Adeno-Associated Virus Porcine Origin capsid protein in complex with Importin-alpha 2
Classification: TRANSPORT PROTEIN
Source organism: Adeno-associated virus - Po1; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.26 Å
Deposited: 2020-12-11
Authors: Hoad, M., Forwood, J.
PDB entry 7l05: Complex of novel maytansinoid M24 bound to T2R-TTL (two tubulin alpha/beta heterodimers, RB3 stathmin-like domain, and tubulin tyrosine ligase)
Classification: STRUCTURAL PROTEIN
Source organism: Gallus gallus; Rattus norvegicus; Sus scrofa
Experimental method: X-RAY DIFFRACTION
Resolution: 2.21 Å
Deposited: 2020-12-11
Authors: Franklin, M.C.
PDB entry 7l06: Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound to two copies of domain-swapped antibody 2G12
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.3 Å
Deposited: 2020-12-11
Authors: Manne, K., Henderson, R., Acharya, P.
PDB entry 7l07: Last common ancestor of HMPPK and PLK/HMPPK vitamin kinases
Classification: TRANSFERASE
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2020-12-11
Authors: Gonzalez-Ordenes, F., Maturana, P., Herrera-Morande, A., Araya, G., Arizabalos, S., Castro-Fernandez, V.
PDB entry 7l08: Cryo-EM structure of the human 55S mitoribosome-RRFmt complex.
Classification: RIBOSOME
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.49 Å
Deposited: 2020-12-11
Authors: Koripella, R., Agrawal, E.K., Deep, A., Agrawal, R.K.
PDB entry 7l09: Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound domain-swapped antibody 2G12 from masked 3D refinement
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.1 Å
Deposited: 2020-12-11
Authors: Manne, K., Henderson, R., Acharya, P.
PDB entry 7l0a: Crystal structure of s-formylglutathione hydrolase (FrmB) from Staphylococcus aureus, apoenzyme
Classification: HYDROLASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2020-12-11
Authors: Miller, J.J., Jez, J.M., Odom John, A.R.
PDB entry 7l0b: Crystal structure of hydroxyacyl glutathione hydrolase (GloB) from Staphylococcus aureus, apoenzyme
Classification: HYDROLASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2020-12-11
Authors: Miller, J.J., Jez, J.M., Odom John, A.R.
PDB entry 7l0c: Ligand-free PTP1B T177G
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2020-12-11
Authors: Shen, R.D., Hengge, A.C., Johnson, S.J.
PDB entry 7l0d: SARS-CoV-2 Main Protease (Mpro) in Complex with ML188
Classification: HYDROLASE/INHIBITOR
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 2.39 Å
Deposited: 2020-12-11
Authors: Lockbaum, G.J., Lee, J.M., Reyes, A.C., Nalivaika, E.A., Ali, A., Yilmaz, N.K., Thompson, P.R., Schiffer, C.A.
PDB entry 7l0e: Crystal structure of bovine RPE65 in complex with gem-difluoro emixustat and palmitate
Classification: HYDROLASE/INHIBITOR
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2020-12-11
Authors: Kiser, P.D.
PDB entry 7l0f: Monobody 12VC3 Bound to HRAS(WT)
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2020-12-11
Authors: Teng, K.W., Hattori, T., Tsai, S., Koide, S.
PDB entry 7l0g: Monobody 12VC1 Bound to HRAS(G12C)
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.54 Å
Deposited: 2020-12-11
Authors: Teng, K.W., Hattori, T., Tsai, S., Koide, S.
PDB entry 7l0h: Vanadate-bound PTP1B T177G
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2020-12-11
Authors: Shen, R.D., Hengge, A.C., Johnson, S.J.
PDB entry 7l0i: Ligand-free YopH G352T
Classification: HYDROLASE
Source organism: Yersinia pestis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.02 Å
Deposited: 2020-12-11
Authors: Shen, R.D., Hengge, A.C., Johnson, S.J.
PDB entry 7l0j: Structure of AMH bound to AMHR2-ECD
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2020-12-11
Authors: Hart, K.N., Thompson, T.B.
PDB entry 7l0k: Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM784 (3-(1-(3-methyl-4-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1H-pyrrole-2-carboxamido)ethyl)-1H-pyrazole-5-carboxamide)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Plasmodium falciparum (isolate 3D7)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.96 Å
Deposited: 2020-12-11
Authors: Deng, X., Phillips, M., Tomchick, D.
PDB entry 7l0l: Cryo-EM structure of the VRC316 clinical trial, vaccine-elicited, human antibody 316-310-1B11 in complex with an H2 CAN05 HA trimer
Classification: IMMUNE SYSTEM/Viral protein
Source organism: Homo sapiens; Influenza A virus (A/Canada/720/2005(H2N2))
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.85 Å
Deposited: 2020-12-11
Authors: Gorman, J., Kwong, P.D.
PDB entry 7l0m: Vanadate-bound YopH G352T
Classification: HYDROLASE
Source organism: Yersinia pestis
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2020-12-11
Authors: Shen, R.D., Hengge, A.C., Johnson, S.J.
PDB entry 7l0n: Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity
Classification: VIRAL PROTEIN/HYDROLASE
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 2.78 Å
Deposited: 2020-12-11
Authors: Snell, G., Czudnochowski, N., Dillen, J., Nix, J.C., Croll, T.I., Corti, D.
PDB entry 7l0o: Streptococcus gordonii C123 Domain(s)-Structural and Functional Analysis
Classification: CELL ADHESION
Source organism: Streptococcus gordonii
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2020-12-11
Authors: Schormann, N., Deivanayagam, C.
PDB entry 7l0p: Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, without AHD
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens; Rattus norvegicus
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.1 Å
Deposited: 2020-12-12
Authors: Zhang, M., Gui, M., Wang, Z., Gorgulla, C., Yu, J.J., Wu, H., Sun, Z., Klenk, C., Merklinger, L., Morstein, L., Hagn, F., Pluckthun, A., Brown, A., Nasr, M.L., Wagner, G.
PDB entry 7l0q: Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, with AHD
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens; Rattus norvegicus
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.3 Å
Deposited: 2020-12-12
Authors: Zhang, M., Gui, M., Wang, Z., Gorgulla, C., Yu, J.J., Wu, H., Sun, Z., Klenk, C., Merklinger, L., Morstein, L., Hagn, F., Pluckthun, A., Brown, A., Nasr, M.L., Wagner, G.
PDB entry 7l0r: Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, without AHD
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens; Rattus norvegicus
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.2 Å
Deposited: 2020-12-12
Authors: Zhang, M., Gui, M., Wang, Z., Gorgulla, C., Yu, J.J., Wu, H., Sun, Z., Klenk, C., Merklinger, L., Morstein, L., Hagn, F., Pluckthun, A., Brown, A., Nasr, M.L., Wagner, G.
PDB entry 7l0s: Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, with AHD
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens; Rattus norvegicus
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.5 Å
Deposited: 2020-12-12
Authors: Zhang, M., Gui, M., Wang, Z., Gorgulla, C., Yu, J.J., Wu, H., Sun, Z., Klenk, C., Merklinger, L., Morstein, L., Hagn, F., Pluckthun, A., Brown, A., Nasr, M.L., Wagner, G.
PDB entry 7l0u: Human Bocavirus 2 (pH 5.5)
Classification: VIRUS
Source organism: Human bocavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.74 Å
Deposited: 2020-12-13
Authors: Luo, M., Mietzsch, M., Agbandje-McKenna, M.
PDB entry 7l0v: Human Bocavirus 2 (pH 7.4)
Classification: VIRUS
Source organism: Human bocavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.71 Å
Deposited: 2020-12-13
Authors: Luo, M., Mietzsch, M., Agbandje-McKenna, M.
PDB entry 7l0w: Human Bocavirus 1 (pH 5.5)
Classification: VIRUS
Source organism: Primate bocaparvovirus 1 (strain Human bocavirus 1 type 1)
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.74 Å
Deposited: 2020-12-13
Authors: Luo, M., Mietzsch, M., Agbandje-McKenna, M.
PDB entry 7l0x: Human Bocavirus 2 (pH 2.6)
Classification: VIRUS
Source organism: Human bocavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.51 Å
Deposited: 2020-12-13
Authors: Luo, M., Mietzsch, M., Agbandje-McKenna, M.
PDB entry 7l0y: Human Bocavirus 1 (pH 2.6)
Classification: VIRUS
Source organism: Primate bocaparvovirus 1 (strain Human bocavirus 1 type 1)
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.54 Å
Deposited: 2020-12-13
Authors: Luo, M., Mietzsch, M., Agbandje-McKenna, M.
PDB entry 7l0z: Spinach variant bound to DFHBI-1T
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2020-12-13
Authors: Truong, L., Trachman, R.J., Ferre-D'Amare, A.R.
PDB entry 7l10: CRYSTAL STRUCTURE OF THE SARS-COV-2 (2019-NCOV) MAIN PROTEASE IN COMPLEX WITH COMPOUND 4
Classification: VIRAL PROTEIN, Hydrolase
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 1.63 Å
Deposited: 2020-12-13
Authors: Deshmukh, M.G., Ippolito, J.A., Stone, E.A., Jorgensen, W.L., Anderson, K.S.
PDB entry 7l11: CRYSTAL STRUCTURE OF THE SARS-COV-2(2019-NCOV) MAIN PROTEASE IN COMPLEX WITH COMPOUND 5
Classification: VIRAL PROTEIN, Hydrolase
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2020-12-14
Authors: Deshmukh, M.G., Ippolito, J.A., Stone, E.A., Jorgensen, W.L., Anderson, K.S.
PDB entry 7l12: CRYSTAL STRUCTURE OF THE SARS-COV-2(2019-NCOV) MAIN PROTEASE IN COMPLEX WITH COMPOUND 14
Classification: VIRAL PROTEIN, Hydrolase
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2020-12-14
Authors: Deshmukh, M.G., Ippolito, J.A., Zhang, C.H., Jorgensen, W.L., Anderson, K.S.
PDB entry 7l13: CRYSTAL STRUCTURE OF THE SARS-COV-2(2019-NCOV) MAIN PROTEASE IN COMPLEX WITH COMPOUND 21
Classification: VIRAL PROTEIN, Hydrolase
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 2.17 Å
Deposited: 2020-12-14
Authors: Deshmukh, M.G., Ippolito, J.A., Zhang, C.H., Jorgensen, W.L., Anderson, K.S.
PDB entry 7l14: CRYSTAL STRUCTURE OF THE SARS-COV-2(2019-NCOV) MAIN PROTEASE IN COMPLEX WITH COMPOUND 26
Classification: VIRAL PROTEIN, Hydrolase
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2020-12-14
Authors: Deshmukh, M.G., Ippolito, J.A., Stone, E.A., Jorgensen, W.L., Anderson, K.S.
PDB entry 7l15: Marsupial T cell receptor Spl_118
Classification: IMMUNE SYSTEM
Source organism: Monodelphis domestica
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2020-12-14
Authors: Wegrecki, M., Kannan Sivaraman, K., Praveena, T., Le Nours, J., Rossjohn, J.
PDB entry 7l16: Crystal structure of sugar-bound melibiose permease MelB
Classification: TRANSPORT PROTEIN
Source organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.15 Å
Deposited: 2020-12-14
Authors: Guan, L.
PDB entry 7l17: Crystal structure of sugar-bound melibiose permease MelB
Classification: TRANSPORT PROTEIN
Source organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.05 Å
Deposited: 2020-12-14
Authors: Guan, L.
PDB entry 7l18: Crystal structure of a tandem deletion mutant of rat NADPH-cytochrome P450 reductase
Classification: FLAVOPROTEIN, OXIDOREDUCTASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.542 Å
Deposited: 2020-12-14
Authors: Hubbard, P.A., Xia, C., Shen, A.L., Kim, J.J.K.
PDB entry 7l19: Crystal structure of the MarR family transcriptional regulator from Enterobacter soli strain LF7 bound to Indole 3 acetic acid
Classification: DNA BINDING PROTEIN
Source organism: Enterobacter soli ATCC BAA-2102
Experimental method: X-RAY DIFFRACTION
Resolution: 2.77 Å
Deposited: 2020-12-14
Authors: Lietzan, A.D., Walton, W.G., Redinbo, M.R., Dangl, J.L.
PDB entry 7l1a: Human Methionine Adenosyltransferase 2A bound to Methylthioadenosine and inhibitor, di-imido triphosphate (PNPNP)
Classification: TRANSFERASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.25 Å
Deposited: 2020-12-14
Authors: Niland, C.N., Fedorov, E., Schramm, V.L., Ghosh, A.
PDB entry 7l1b: Crystal structure of HLA-A*03:01 in complex with a wild-type PIK3CA peptide
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.04 Å
Deposited: 2020-12-14
Authors: Ma, J., Baker, B.M.
PDB entry 7l1c: Crystal structure of HLA-A*03:01 in complex with a mutant PIK3CA peptide
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.96 Å
Deposited: 2020-12-14
Authors: Ma, J., Baker, B.M.