LiteFold/PDB huggingface dataset:
PDB entry 5tpc: Binding domain of BoNT/A complexed with ganglioside
Classification: HYDROLASE
Source organism: Clostridium botulinum
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2016-10-20
Authors: Berntsson, R.P.-A., Svensson, L.M., Stenmark, P.
PDB entry 5tpg: Optimization of spirocyclic proline tryptophanhydroxylase-1 inhibitors
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2016-10-20
Authors: Stein, A.J., Goldberg, D.R., De Lombaert, S., Holt, M.C.
PDB entry 5tph: Crystal structure of a de novo designed protein homodimer with curved beta-sheet
Classification: DE NOVO PROTEIN
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 2.47 Å
Deposited: 2016-10-20
Authors: Basanta, B., Marcos, E., Oberdorfer, G., Chidyausiku, T.M., Sankaran, B., Baker, D.
PDB entry 5tpi: 1.47 Angstrom Crystal Structure of the C-terminal Substrate Binding Domain of LysR Family Transcriptional Regulator from Klebsiella pneumoniae.
Classification: HYDROLASE
Source organism: Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.47 Å
Deposited: 2016-10-20
Authors: Minasov, G., Wawrzak, Z., Sandoval, J., Evdokimova, E., Grimshaw, S., Kwon, K., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5tpj: Crystal structure of a de novo designed protein with curved beta-sheet
Classification: DE NOVO PROTEIN
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 3.101 Å
Deposited: 2016-10-20
Authors: Basanta, B., Oberdorfer, G., Marcos, E., Chidyausiku, T.M., Sankaran, B., Baker, D.
PDB entry 5tpk: Crystal Structure of Mouse Protocadherin-15 EC7-8 V875A
Classification: CELL ADHESION
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2016-10-20
Authors: Chen, C., Sotomayor, M.
PDB entry 5tpl: Crystal Structure of DH270.3 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2016-10-20
Authors: Fera, D., Harrison, S.C.
PDB entry 5tpm: 2.8 Angstrom Crystal Structure of the C-terminal Dimerization Domain of Transcriptional Regulator PdhR from Escherichia coli.
Classification: HYDROLASE
Source organism: Escherichia coli O6:H1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2016-10-20
Authors: Minasov, G., Wawrzak, Z., Sandoval, J., Skarina, T., Grimshaw, S., Kwon, K., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5tpn: Crystal structure of RSV F in complex with human antibody hRSV90
Classification: IMMUNE SYSTEM
Source organism: Enterobacteria phage Ox2; Homo sapiens; Human respiratory syncytial virus A
Experimental method: X-RAY DIFFRACTION
Resolution: 3.141 Å
Deposited: 2016-10-20
Authors: Mousa, J.J., Crowe, J.E.
PDB entry 5tpp: Crystal Structure of DH270.5 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2016-10-20
Authors: Fera, D., Harrison, S.C.
PDB entry 5tpq: E. coli alkaline phosphatase D101A, D153A, R166S, E322A, K328A mutant
Classification: HYDROLASE
Source organism: Escherichia coli (strain K12)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.45 Å
Deposited: 2016-10-20
Authors: Sunden, F., AlSadhan, I., Lyubimov, A.Y., Doukov, T., Swan, J., Herschlag, D.
PDB entry 5tpr: Desmethyl-4-deoxygadusol synthase from Anabaena variabilis (Ava_3858) with NAD+ and Zn2+ bound
Classification: LYASE
Source organism: Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2016-10-21
Authors: Kean, K.M., Karplus, P.A.
PDB entry 5tps: Structure of a Fc heterodimer
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2016-10-21
Authors: Zhou, A., Wei, H.
PDB entry 5tpt: The Crystal Structure of Amyloid Precursor-Like Protein 2 (APLP2) E2 Domain
Classification: PROTEIN FIBRIL
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.422 Å
Deposited: 2016-10-21
Authors: Roisman, L.C., Cappai, R.
PDB entry 5tpu: x-ray structure of the WlaRB TDP-quinovose 3,4-ketoisomerase from campylobacter jejuni
Classification: ISOMERASE
Source organism: Campylobacter jejuni
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2016-10-21
Authors: Holden, H.M., Thoden, J.B., Li, J.Z., Riegert, A.S., Goneau, M.-F., Cunningham, A.M., Vinogradov, E., Schoenhofen, I.C., Gilbert, M.
PDB entry 5tpv: X-ray structure of WlaRA (TDP-fucose-3,4-ketoisomerase) from Campylobacter jejuni
Classification: ISOMERASE
Source organism: Campylobacter jejuni subsp. jejuni 81116
Experimental method: X-RAY DIFFRACTION
Resolution: 2.14 Å
Deposited: 2016-10-21
Authors: Holden, H.M., Thoden, J.B., Li, Z.A., Riegert, A.S., Goneau, M.-F., Cunningham, A.M., Vinograd, E., Schoenhofen, I.C., Gilbert, M., Li, J.
PDB entry 5tpw: Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in complex with zinc at the GluN2A
Classification: TRANSPORT PROTEIN
Source organism: Mus musculus; Rattus norvegicus; Xenopus laevis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.909 Å
Deposited: 2016-10-21
Authors: Romero-Hernandez, A., Simorowski, N., Karakas, E., Furukawa, H.
PDB entry 5tpx: Bromodomain from Plasmodium Faciparum Gcn5, complexed with compound
Classification: TRANSFERASE
Source organism: Plasmodium falciparum (isolate 3D7)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2016-10-21
Authors: Lin, Y.H., Hou, C.F.D., MOUSTAKIM, M., DIXON, D.J., Loppnau, P., Tempel, W., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Hui, R., BRENNAN, P.E., Walker, J.R., Structural Genomics Consortium (SGC)
PDB entry 5tpy: Crystal structure of an exonuclease resistant RNA from Zika virus
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.805 Å
Deposited: 2016-10-21
Authors: Akiyama, B.M., Laurence, H.M., Massey, A.R., Costantino, D.A., Xie, X., Yang, Y., Shi, P.-Y., Nix, J.C., Beckham, J.D., Kieft, J.S.
PDB entry 5tpz: Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2B in apo closed state
Classification: TRANSPORT PROTEIN
Source organism: Rattus norvegicus; Xenopus laevis
Experimental method: X-RAY DIFFRACTION
Resolution: 3.095 Å
Deposited: 2016-10-21
Authors: Romero-Hernandez, A., Simorwski, N., Karakas, E., Furukawa, H.
PDB entry 5tq0: Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in the presence of EDTA
Classification: TRANSPORT PROTEIN
Source organism: Mus musculus; Rattus norvegicus; Xenopus laevis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2016-10-21
Authors: Romero-Hernandez, A., Simorowski, N., Karakas, E., Furukawa, H.
PDB entry 5tq1: Phospholipase C gamma-1 C-terminal SH2 domain bound to a phosphopeptide derived from the insulin receptor
Classification: HYDROLASE
Source organism: Bos taurus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.485 Å
Deposited: 2016-10-21
Authors: Wuttke, D.S., McKercher, M.A.
PDB entry 5tq2: Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in complex with zinc at GluN1 and GluN2A
Classification: TRANSPORT PROTEIN
Source organism: Mus musculus; Rattus norvegicus; Xenopus laevis
Experimental method: X-RAY DIFFRACTION
Resolution: 3.289 Å
Deposited: 2016-10-21
Authors: Romero-Hernandez, A., Simorowski, N., Karakas, E., Furukawa, H.
PDB entry 5tq3: Design and Synthesis of a pan-JAK kinase inhibitor clinical candidate (PF-06263276) suitable for the treatment of inflammatory diseases of the lungs and skin
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.69 Å
Deposited: 2016-10-23
Authors: Chrencik, J., Jones, P.
PDB entry 5tq4: Design and Synthesis of a pan-JAK Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2016-10-23
Authors: Chrencik, J., Jones, P.
PDB entry 5tq5: Design and Synthesis of a pan-JAK Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2016-10-23
Authors: Chrencik, J., Jones, P.
PDB entry 5tq6: Design and Synthesis of a pan-JAK Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.06 Å
Deposited: 2016-10-23
Authors: Chrencik, J., Jones, P.
PDB entry 5tq7: Design and Synthesis of a pan-JAK Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2016-10-23
Authors: Chrencik, J., Jones, P.
PDB entry 5tq8: Design and Synthesis of a pan-JAK Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.59 Å
Deposited: 2016-10-23
Authors: Chrencik, J., Jones, P.
PDB entry 5tqa: Crystal Structure of DH270.6 (unliganded) from the DH270 Broadly Neutralizing N332-Glycan Dependent Lineage
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.723 Å
Deposited: 2016-10-23
Authors: Fera, D., Harrison, S.C.
PDB entry 5tqb: Crystal structure of assembly chaperone of ribosomal protein L4 (Acl4) in complex with ribosomal protein L4 (RpL4)
Classification: RIBOSOMAL PROTEIN
Source organism: Chaetomium thermophilum; Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2016-10-23
Authors: Huber, F.M., Hoelz, A.
PDB entry 5tqc: Crystal structure of transport factor karyopherin-beta 2 in complex with the PY-NLS of ribosomal protein L4 (RpL4)
Classification: RIBOSOMAL PROTEIN
Source organism: Chaetomium thermophilum; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2016-10-23
Authors: Huber, F.M., Hoelz, A.
PDB entry 5tqe: Factor VIIa in complex with the inhibitor (5R)-5-[(1-aminoisoquinolin-6-yl)amino]-19-(cyclopropylsulfonyl)-3-methyl-13-oxa-3,15-diazatricyclo[14.3.1.1~6,10~]henicosa-1(20),6(21),7,9,16,18-hexaene-4,14-dione
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2016-10-24
Authors: Wei, A.
PDB entry 5tqf: Factor VIIa in complex with the inhibitor (11R)-11-[(1-aminoisoquinolin-6-yl)amino]-16-(cyclopropylsulfonyl)-13-methyl-2,13-diazatricyclo[13.3.1.1~6,10~]icosa-1(19),6(20),7,9,15,17-hexaene-3,12-dione
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2016-10-24
Authors: Wei, A.
PDB entry 5tqg: Factor VIIa in complex with the inhibitor (5R,11R)-11-[(1-amino-4-fluoroisoquinolin-6-yl)amino]-16-(cyclopropylsulfonyl)-7-(2,2-difluoroethoxy)-5,13-dimethyl-2,13-diazatricyclo[13.3.1.1~6,10~]icosa-1(19),6(20),7,9,15,17-hexaene-3,12-dione
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2016-10-24
Authors: Wei, A.
PDB entry 5tqh: IDH1 R132H mutant in complex with IDH889
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2016-10-24
Authors: Xie, X., Kulathila, R.
PDB entry 5tqi: Crystal structure of a pyridoxal kinase from Burkholderia multivorans
Classification: TRANSFERASE
Source organism: Burkholderia multivorans (strain ATCC 17616 / 249)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2016-10-24
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5tqj: Crystal structure of response regulator receiver protein from Burkholderia phymatum
Classification: SIGNALING PROTEIN
Source organism: Burkholderia phymatum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.3 Å
Deposited: 2016-10-24
Authors: Edwards, T.E., Dranow, D.M., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5tql: Crystal structure of TIM-Barrel protein HisF-C9S
Classification: LYASE
Source organism: Thermotoga maritima
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2016-10-24
Authors: Bender, B.J., Meiler, J.
PDB entry 5tqm: Cinnamoyl-CoA Reductase 1 from Sorghum bicolor in complex with NADP+
Classification: OXIDOREDUCTASE
Source organism: Sorghum bicolor
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2016-10-24
Authors: Sattler, S.A., Kang, C.H.
PDB entry 5tqn: Lipoxygenase-1 (soybean) L546A mutant at 293K
Classification: OXIDOREDUCTASE
Source organism: Glycine max
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2016-10-24
Authors: Poss, E.M., Fraser, J.S., Gee, C.
PDB entry 5tqo: Lipoxygenase-1 (soybean) L546A/L754A mutant at 300K
Classification: OXIDOREDUCTASE
Source organism: Glycine max
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2016-10-24
Authors: Poss, E.M., Fraser, J.S., Gee, C.
PDB entry 5tqp: LIPOXYGENASE-1 (SOYBEAN) I553G MUTANT AT 300K
Classification: OXIDOREDUCTASE
Source organism: Glycine max
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2016-10-24
Authors: Poss, E.M., Fraser, J.S.
PDB entry 5tqq: Cryo-electron microscopy structure of a bovine CLC-K chloride channel, main (class 1) conformation
Classification: TRANSPORT PROTEIN
Source organism: Bos taurus; Mus musculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.76 Å
Deposited: 2016-10-24
Authors: Park, E., MacKinnon, R.
PDB entry 5tqr: ctPRC2 in an autoinhibited conformation bound to S-adenosylmethionine
Classification: TRANSFERASE
Source organism: Chaetomium thermophilum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.571 Å
Deposited: 2016-10-24
Authors: Bratkowski, M.A., Liu, X.
PDB entry 5tqs: Phospholipase C gamma-1 C-terminal SH2 domain bound to a phosphopeptide derived from the receptor tyrosine kinase ErbB2
Classification: HYDROLASE
Source organism: Bos taurus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.876 Å
Deposited: 2016-10-24
Authors: Wuttke, D.S., McKercher, M.A.
PDB entry 5tqu: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor
Classification: Ligase/Ligase Inhibitor
Source organism: Trypanosoma brucei brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2016-10-24
Authors: Barros-Alvarez, X., Hol, W.G.J.
PDB entry 5tqv: Crystal structure of NADP-dependent carbonyl reductase from Burkholderia multivorans
Classification: OXIDOREDUCTASE
Source organism: Burkholderia multivorans (strain ATCC 17616 / 249)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2016-10-24
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5tqw: CryoEM reconstruction of human IKK1, open conformation 1
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 5.6 Å
Deposited: 2016-10-24
Authors: Lyumkis, D., Ghosh, G., Polley, S., Biswas, T., Huang, D., Passos, D.O.
PDB entry 5tqx: CryoEM reconstruction of human IKK1, intermediate conformation 2
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 5.4 Å
Deposited: 2016-10-24
Authors: Lyumkis, D., Ghosh, G., Polley, S., Biswas, T., Huang, D., Passos, D.O.
PDB entry 5tqy: CryoEM reconstruction of human IKK1, closed conformation 3
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 5.2 Å
Deposited: 2016-10-24
Authors: Lyumkis, D., Ghosh, G., Polley, S., Biswas, T., Huang, D., Passos, D.O.
PDB entry 5tqz: Frutapin complexed with alpha-D-glucose
Classification: Carbohydrate-binding protein
Source organism: Artocarpus altilis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2016-10-25
Authors: Sousa, F.D., Guo, J., Coker, A.R., Monteiro-Moreira, A.C.O., Moreira, R.A.
PDB entry 5tr0: Lipoxygenase-1 (soybean) L754A mutant at 293K
Classification: OXIDOREDUCTASE
Source organism: Glycine max
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2016-10-24
Authors: Poss, E.M., Fraser, J.S.
PDB entry 5tr1: Cryo-electron microscopy structure of a bovine CLC-K chloride channel, alternate (class 2) conformation
Classification: TRANSPORT PROTEIN
Source organism: Bos taurus; Mus musculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.95 Å
Deposited: 2016-10-25
Authors: Park, E., MacKinnon, R.
PDB entry 5tr2: Crystal structure of the D263G missense variant of human PGM1
Classification: ISOMERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2016-10-25
Authors: Beamer, L.J., Stiers, K.M.
PDB entry 5tr3: 2.5 Angstrom Resolution Crystal Structure of Dihydrolipoyl Dehydrogenase from Pseudomonas putida in Complex with FAD.
Classification: HYDROLASE
Source organism: Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2016-10-25
Authors: Minasov, G., Wawrzak, Z., Shuvalova, L., Kiryukhina, O., Dubrovska, I., Grimshaw, S., Kwon, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5tr4: Structure of Ubiquitin activating enzyme (Uba1) in complex with ubiquitin and TAK-243
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Bos taurus; Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2016-10-25
Authors: Sintchak, M.D.
PDB entry 5tr5: Solution structure of Serine 65 phosphorylated UBL domain from parkin
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: SOLUTION NMR
Deposited: 2016-10-25
Authors: Aguirre, J.D., Dunkerley, K.M., Mercier, P., Shaw, G.S.
PDB entry 5tr6: Discovery of TAK-659, an Orally Available Investigational Inhibitor of Spleen Tyrosine Kinase (SYK)
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.93 Å
Deposited: 2016-10-25
Authors: Yano, J., Jennings, A., Lam, B., Hoffman, I.D.
PDB entry 5tr7: Crystal structure of a putative D-alanyl-D-alanine carboxypeptidase from Vibrio cholerae O1 biovar eltor str. N16961
Classification: PENICILLIN-BINDING PROTEIN
Source organism: Vibrio cholerae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2016-10-25
Authors: Filippova, E.V., Minasov, G., Shuvalova, L., Kiryukhina, O., Dubrovska, I., Shatsman, S., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5tr8: Crystal structure of vaccine-elicited pan- influenza H1N1 neutralizing murine antibody 441D6.
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.01 Å
Deposited: 2016-10-25
Authors: Joyce, M.G., Kanekiyo, M., Mascola, J.R., Graham, B.S., Kwong, P.D.
PDB entry 5tr9: Crystal Structure of a ferredoxin NADP+ reductase from Neisseria gonorrhoeae with bound FAD
Classification: OXIDOREDUCTASE
Source organism: Neisseria gonorrhoeae MIA_2011_03-10
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2016-10-25
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5trb: Crystal structure of the RNF20 RING domain
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2016-10-25
Authors: Foglizzo, M., Middleton, A.J., Day, C.L.
PDB entry 5trc: Crystal structure of phosphorylated AC3-AC5 domains of yeast acetyl-CoA carboxylase
Classification: LIGASE
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2016-10-26
Authors: Wei, J., Tong, L.
PDB entry 5trd: Structure of RbkR (Riboflavin Kinase) from Thermoplasma acidophilum determined in complex with CTP and its cognate DNA operator
Classification: TRANSFERASE/DNA
Source organism: Thermoplasma acidophilum; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2016-10-26
Authors: Vetting, M.W., Rodionova, I.A., Li, X., Osterman, A.L., Rodionov, D.A., Almo, S.C.
PDB entry 5tre: Zinc and the Iron Donor Frataxin Regulate Oligomerization of the Scaffold Protein to Form New Fe-S Cluster Assembly Centers
Classification: OXIDOREDUCTASE
Source organism: Saccharomyces cerevisiae
Experimental method: ELECTRON MICROSCOPY
Resolution: 15.6 Å
Deposited: 2016-10-26
Authors: Ranatunga, W., Gakh, O., Galeano, B.K., Smith IV, D.Y., Thompson, J.R., Isaya, G.
PDB entry 5trf: MDM2 in complex with SAR405838
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2016-10-26
Authors: Meagher, J.L., Stuckey, J.A.
PDB entry 5trg: Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide DPLG-2
Classification: HYDROLASE/HYDROLASE inhibitor
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.804 Å
Deposited: 2016-10-26
Authors: Hsu, H.-C., Fan, H., Singh, R.K., Wang, R., Sukenick, G., Nathan, C., Lin, G., Li, H.
PDB entry 5trh: CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-[(benzenecarbonyl)amino]-3-[(4-chlorophenyl)methoxy]benzoic acid
Classification: TRANSFERASE/TRANSFERASE inhibitor
Source organism: Hepatitis C virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2016-10-26
Authors: Sheriff, S.
PDB entry 5tri: CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 3-[(4-chlorophenyl)methoxy]-2-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)benzoic acid
Classification: TRANSFERASE/TRANSFERASE inhibitor
Source organism: Hepatitis C virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2016-10-26
Authors: Sheriff, S.
PDB entry 5trj: CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-{[2-(carboxymethoxy)benzene-1-carbonyl]amino}-3-[(4-chlorophenyl)methoxy]benzoic acid
Classification: TRANSFERASE/TRANSFERASE inhibitor
Source organism: Hepatitis C virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.57 Å
Deposited: 2016-10-26
Authors: Sheriff, S.
PDB entry 5trk: CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA- DEPENDENT RNA POLYMERASE IN COMPLEX WITH N-{3-[(benzenecarbonyl)amino]-4-[(4-chlorophenyl)methoxy]benzene-1-carbonyl}glycine
Classification: TRANSFERASE/TRANSFERASE inhibitor
Source organism: Hepatitis C virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.06 Å
Deposited: 2016-10-26
Authors: Sheriff, S.
PDB entry 5trl: Crystal structure of human GCN5 histone acetyltransferase domain
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.299 Å
Deposited: 2016-10-26
Authors: Guo, Y.R., Tao, Y.J.
PDB entry 5trm: Crystal structure of human GCN5 histone acetyltransferase domain
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2016-10-26
Authors: Guo, Y.R., Tao, Y.J.
PDB entry 5trn: Solution Structure of a DNA Dodecamer with 8-oxoguanine at the 4th position and 5-methylcytosine at the 9th position
Classification: DNA
Experimental method: SOLUTION NMR
Deposited: 2016-10-26
Authors: Hoppins, J.J., Gruber, D.R., Miears, H.L., Endutkin, A.V., Zharkov, D.O., Smirnov, S.L.
PDB entry 5tro: 1.8 Angstrom Resolution Crystal Structure of Dimerization and Transpeptidase domains (residues 39-608) of Penicillin-Binding Protein 1 from Staphylococcus aureus.
Classification: HYDROLASE
Source organism: Staphylococcus aureus (strain COL)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2016-10-26
Authors: Minasov, G., Shuvalova, L., Kiryukhina, O., Dubrovska, I., Grimshaw, S., Kwon, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5trp: Crystal Structure of the Unliganded DH270 Cooperating Lineage Member DH272
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.692 Å
Deposited: 2016-10-27
Authors: Fera, D., Harrison, S.C.
PDB entry 5trq: WELO5 SMALL MOLECULE HALOGENASE WITH NI(II) AND SUCCINATE
Classification: OXIDOREDUCTASE
Source organism: Hapalosiphon welwitschii UTEX B 1830
Experimental method: X-RAY DIFFRACTION
Resolution: 1.3 Å
Deposited: 2016-10-27
Authors: McDonough, M.A., Gallimore, E., Clifton, I.J.
PDB entry 5trr: Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2169
Classification: HYDROLASE/HYDROLASE inhibitor
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 3.103 Å
Deposited: 2016-10-27
Authors: Hsu, H.-C., Fan, H., Singh, P.K., Wang, R., Sukenick, G., Nathan, C., Lin, G., Li, H.
PDB entry 5trs: Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2144
Classification: HYDROLASE/HYDROLASE inhibitor
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 3.08357 Å
Deposited: 2016-10-27
Authors: Hsu, H.-C., Fan, H., Singh, P.K., Wang, R., Sukenick, G., Nathan, C., Lin, G., Li, H.
PDB entry 5trt: Crystal Structure of enoyl-(acyl carrier protein) reductase from Burkholderia pseudomallei 1710b bound to NAD
Classification: OXIDOREDUCTASE
Source organism: Burkholderia pseudomallei (strain 1710b)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2016-10-27
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5tru: Structure of the first-in-class checkpoint inhibitor Ipilimumab bound to human CTLA-4
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2016-10-27
Authors: Ramagopal, U.A., Liu, W., Garrett-Thomson, S.C., Yan, Q., Srinivasan, M., Wong, S.C., Bell, A., Mankikar, S., Rangan, V.S., Deshpande, S., Bonanno, J.B., Korman, A.J., Almo, S.C.
PDB entry 5trv: Crystal structure of a de novo designed protein with curved beta-sheet
Classification: DE NOVO PROTEIN
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 2.91 Å
Deposited: 2016-10-27
Authors: Basanta, B., Oberdorfer, G., Marcos, E., Chidyausiku, T.M., Sankaran, B., Baker, D.
PDB entry 5trw: Crystal structure of Pyridoxamine kinase PDXY from Burkholderia xenovorans
Classification: TRANSFERASE
Source organism: Burkholderia xenovorans (strain LB400)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2016-10-27
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5trx: Room temperature structure of an extradiol ring-cleaving dioxygenase from B.fuscum determined using serial femtosecond crystallography
Classification: OXIDOREDUCTASE
Source organism: Brevibacterium fuscum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.38 Å
Deposited: 2016-10-27
Authors: Kovaleva, E.G., Oberthuer, D., Tolstikova, A., Mariani, V.
PDB entry 5try: Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2206
Classification: HYDROLASE/HYDROLASE inhibitor
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 3.00001 Å
Deposited: 2016-10-27
Authors: Hsu, H.-C., Fan, H., Singh, P.K., Wang, R., Sukenick, G., Nathan, C., Lin, G., Li, H.
PDB entry 5trz: Crystal structure of MHC-I H2-KD complexed with peptides of Mycobacterial tuberculosis (YQSGLSIVM)
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.247 Å
Deposited: 2016-10-27
Authors: Jiang, J., Natarajan, K., Margulies, D.
PDB entry 5ts0: Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2208
Classification: HYDRONLASE/HYDROLASE inhibitor
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8468 Å
Deposited: 2016-10-27
Authors: Hsu, H.-C., Fan, H., Singh, P.K., Wang, R., Sukenick, G., Nathan, C., Lin, G., Li, H.
PDB entry 5ts1: Crystal structure of MHC-I H2-KD complexed with peptides of Mycobacterial tuberculosis (YYQSGLSIV)
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2016-10-27
Authors: Jiang, J., Natarajan, K., Margulies, D.
PDB entry 5ts2: Crystal structure of a phosphopantetheine adenylyltransferase (CoaD, PPAT) from Pseudomonas aeruginosa bound to dephospho coenzyme A
Classification: TRANSFERASE
Source organism: Pseudomonas aeruginosa (strain LESB58)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2016-10-27
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5ts3: Crystal Structure of a 3-oxoacyl-[acyl-carrier protein] Reductase with bound NAD from Brucella melitensis
Classification: OXIDOREDUCTASE
Source organism: Brucella melitensis biotype 2 (strain ATCC 23457)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2016-10-27
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5ts4: Crystal structure of a de novo designed protein with curved beta-sheet
Classification: DE NOVO PROTEIN
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 3.005 Å
Deposited: 2016-10-27
Authors: Basanta, B., Oberdorfer, G., Chidyausiku, T.M., Marcos, E., Pereira, J.H., Sankaran, B., Zwart, P.H., Baker, D.
PDB entry 5ts5: Crystal structure of L-amino acid oxidase from Bothrops atrox
Classification: OXIDOREDUCTASE
Source organism: Bothrops atrox
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2016-10-27
Authors: Feliciano, P.R., Nonato, M.C.
PDB entry 5ts8: Z. MAYS CK2 KINASE ALPHA SUBUNIT IN COMPLEX WITH THE ATP-COMPETITIVE INHIBITOR 5,6-DIBROMOBENZOTRIAZOLE
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Zea mays
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2016-10-28
Authors: Winiewska, M., Kucinska, K., Czapinska, H., Piasecka, A., Bochtler, M., Poznanski, J.
PDB entry 5ts9: Crystal structure of Chorismate mutase from Burkholderia phymatum
Classification: ISOMERASE
Source organism: Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2016-10-28
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5tsa: Crystal structure of the Zrt-/Irt-like protein from Bordetella bronchiseptica with bound Zn2+
Classification: METAL BINDING PROTEIN
Source organism: Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2016-10-28
Authors: Zhang, T., Fellner, M., Sui, D., Liu, J., Hu, J.
PDB entry 5tsb: Crystal structure of the Zrt-/Irt-like protein from Bordetella bronchiseptica with bound Cd2+
Classification: METAL BINDING PROTEIN
Source organism: Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2016-10-28
Authors: Zhang, T., Fellner, M., Sui, D., Liu, J., Hu, J.
PDB entry 5tsc: The crystal structure of Lpg2147 from Legionella pneumophila
Classification: UNKNOWN FUNCTION
Source organism: Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.008 Å
Deposited: 2016-10-28
Authors: Valleau, D., Xu, X., Cui, H., Joachimiak, A., Savchenko, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 5tsd: Crystal structure of NADPH-dependent 2-hydroxyacid dehydrogenase from Rhizobium etli CFN 42 in complex with NADPH and oxalate
Classification: OXIDOREDUCTASE
Source organism: Rhizobium etli (strain CFN 42 / ATCC 51251)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2016-10-28
Authors: Matelska, D., Shabalin, I.G., Kutner, J., Handing, K.B., Gasiorowska, O.A., Cooper, D.R., Minor, W., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 5tse: 2.35 Angstrom Crystal Structure Minor Lipoprotein from Acinetobacter baumannii.
Classification: LIPID BINDING PROTEIN
Source organism: Acinetobacter baumannii
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2016-10-28
Authors: Minasov, G., Shuvalova, L., Kiryukhina, O., Dubrovska, I., Grimshaw, S., Kwon, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5tsf: Crystal structure of AChBP from Aplysia californica complex with 2-aminopyrimidine at pH 7.0 spacegroup P212121
Classification: METAL BINDING PROTEIN
Source organism: Aplysia californica
Experimental method: X-RAY DIFFRACTION
Resolution: 2.286 Å
Deposited: 2016-10-28
Authors: Camacho-Hernandez, G.A., Kaczanowska, K., Harel, M., Finn, M.G., Taylor, P.W.
PDB entry 5tsg: PilB from Geobacter metallireducens bound to ADP
Classification: ATP-BINDING PROTEIN
Source organism: Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.4011 Å
Deposited: 2016-10-28
Authors: McCallum, M., Tammam, S., Khan, A., Burrows, L., Howell, P.L.
PDB entry 5tsh: PilB from Geobacter metallireducens bound to AMP-PNP
Classification: ATP-BINDING PROTEIN
Source organism: Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2016-10-28
Authors: McCallum, M., Tammam, S., Khan, A., Burrows, L., Howell, P.L.
PDB entry 5tsj: Thermus thermophilus V/A-ATPase bound to VH dAbs
Classification: membrane protein, hydrolase
Source organism: Homo sapiens; Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Experimental method: ELECTRON MICROSCOPY
Resolution: 8.7 Å
Deposited: 2016-10-29
Authors: Davies, R.B., Smits, C., Wong, A.S.W., Stock, D., Sandin, S., Stewart, A.G.
PDB entry 5tsk: Molecular Dynamics Flexible Fitting Model of Coxsackievirus A16 empty Procapsid VP1 Subunit
Classification: VIRAL PROTEIN
Source organism: Coxsackievirus A16
Experimental method: ELECTRON MICROSCOPY
Resolution: 6.5 Å
Deposited: 2016-10-29
Authors: Fan, C., Cong, Y., Ye, X., Huang, Z.
PDB entry 5tsl: Molecular Dynamics Flexible Fitting Model of Coxsackievirus A16 empty Procapsid VP3 Subunit
Classification: VIRAL PROTEIN
Source organism: Coxsackievirus A16
Experimental method: ELECTRON MICROSCOPY
Resolution: 6.5 Å
Deposited: 2016-10-29
Authors: Fan, C., Cong, Y., Ye, X., Huang, Z.
PDB entry 5tsn: Crystal structures of Norwalk virus polymerase bound to an RNA primer-template duplex
Classification: TRANSFERASE/RNA
Source organism: Norwalk virus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2016-10-30
Authors: Shaik, M.M., Ng, K.K.
PDB entry 5tso: CRYSTAL STRUCTURE OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM PIG MUSCLE COMPLEXED WITH ORTHOPHENANTHROLINE AT 1.90 ANGSTROM RESOLUTION
Classification: OXIDOREDUCTASE
Source organism: Sus scrofa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2016-10-30
Authors: Dimova, M., Devedjiev, Y.D.
PDB entry 5tsp: Crystal structure of the catalytic domain of Clostridium perfringens neuraminidase (NanI) in complex with a CHES
Classification: HYDROLASE
Source organism: Clostridium perfringens ATCC 13124
Experimental method: X-RAY DIFFRACTION
Resolution: 1.24 Å
Deposited: 2016-10-31
Authors: Lee, Y., Youn, H.-S., Lee, J.-G., An, J.Y., Park, K.R., Kang, J.Y., Jin, M.S., Ryu, Y.B., Park, K.H., Eom, S.H.
PDB entry 5tsq: Crystal structure of IUnH from Leishmania braziliensis in complex with D-Ribose
Classification: HYDROLASE
Source organism: Leishmania braziliensis braziliensis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.53 Å
Deposited: 2016-10-31
Authors: Bachega, J.F.R., Timmers, L.F.S.M., Dalberto, P.F., Martinelli, L., Pinto, A.F.M., Basso, L.A., Norberto de Souza, O., Santos, D.S.
PDB entry 5tsr: Crystal structure of PRL-3 phosphatase in complex with the Bateman domain of CNNM3 magnesium transporter
Classification: METAL TRANSPORT
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.188 Å
Deposited: 2016-10-31
Authors: Kozlov, G., Zhang, H., Gehring, K.
PDB entry 5tss: TOXIC SHOCK SYNDROME TOXIN-1: ORTHORHOMBIC P222(1) CRYSTAL FORM
Classification: TOXIN
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 1996-12-11
Authors: Prasad, G.S., Radhakrishnan, R., Mitchell, D.T., Earhart, C.A., Dinges, M.M., Cook, W.J., Schlivert, P.M., Ohlendorf, D.H.
PDB entry 5tsu: Active conformation for Engineered human cystathionine gamma lyase (E59N, R119L, E339V) to depleting methionine
Classification: LYASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2016-10-31
Authors: Yan, W., Zhang, Y.
PDB entry 5tsv: HIV-1 CA hexamer with NUP153 peptide - R3 crystal form
Classification: VIRAL PROTEIN
Source organism: Human immunodeficiency virus type 1 group M subtype B (isolate NY5); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.502 Å
Deposited: 2016-10-31
Authors: Skorupka, K., Ganser-Pornillos, B.K., Pornillos, O.
PDB entry 5tsw: HIGH RESOLUTION CRYSTAL STRUCTURE OF A HUMAN TNF-ALPHA MUTANT
Classification: LYMPHOKINE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 1999-04-22
Authors: Cha, S.-S., Kim, J.-S., Cho, H.-S., Oh, B.-H.
PDB entry 5tsx: HIV-1 CA hexamer with NUP153 peptide - P1 crystal form
Classification: VIRAL PROTEIN
Source organism: Human immunodeficiency virus type 1 group M subtype B (isolate NY5); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.899 Å
Deposited: 2016-10-31
Authors: Skorupka, K., Ganser-Pornillos, B.K., Pornillos, O.
PDB entry 5tsy: Structure of the glycoside hydrolase domain of PelA variant E218A from Pseudomonas aeruginosa
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2016-10-31
Authors: Baker, P., Pfoh, R., Howell, P.L.
PDB entry 5tsz: Crystal structure of Plasmodium vivax CelTOS
Classification: CELL INVASION
Source organism: Plasmodium vivax
Experimental method: X-RAY DIFFRACTION
Resolution: 3.002 Å
Deposited: 2016-10-31
Authors: Tolia, N.H., Jimah, J.R.
PDB entry 5tt0: Crystal Structure of an Oxidoreductase (short chain dehydrogenase/reductase family) from Burkholderia thailandensis
Classification: OXIDOREDUCTASE
Source organism: Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2016-10-31
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5tt1: Crystal Structure of a Putative short-chain alcohol dehydrogenase from Burkholderia multivorans
Classification: OXIDOREDUCTASE
Source organism: Burkholderia multivorans (strain ATCC 17616 / 249)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2016-10-31
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5tt2: Inactive conformation of engineered human cystathionine gamma lyase (E59N, R119L, E339V) to depleting methionine
Classification: LYASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.949 Å
Deposited: 2016-10-31
Authors: Yan, W., Zhang, Y.
PDB entry 5tt3: Crystal structure of the complex of Helicobacter pylori alpha-carbonic anhydrase with ethoxzolamide
Classification: LYASE
Source organism: Helicobacter pylori (strain ATCC 700392 / 26695)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2016-11-01
Authors: Modak, J.K., Roujeinikova, A.
PDB entry 5tt4: Determining the Molecular Basis For Starter Unit Selection During Daunorubicin Biosynthesis
Classification: TRANSFERASE
Source organism: Streptomyces peucetius
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2016-11-01
Authors: Jackson, D.R., Valentic, T.R., Patel, A., Tsai, S.C., Mohammed, L., Vasilakis, K., Wattana-amorn, P., Long, P.F., Crump, M.P., Crosby, J.
PDB entry 5tt5: Escherichia coli LigA (K115M) in complex with NAD+
Classification: LIGASE
Source organism: Escherichia coli (strain K12)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.552 Å
Deposited: 2016-11-01
Authors: Goldgur, Y., Unciuleac, M.-C., Shuman, S.H.
PDB entry 5tt6: T4 RNA Ligase 1 (K99M)
Classification: LIGASE
Source organism: Enterobacteria phage T4
Experimental method: X-RAY DIFFRACTION
Resolution: 2.187 Å
Deposited: 2016-11-01
Authors: Goldgur, Y., Unciuleac, M.-C., Shuman, S.H.
PDB entry 5tt7: Discovery of TAK-659, an Orally Available Investigational Inhibitor of Spleen Tyrosine Kinase (SYK)
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.77 Å
Deposited: 2016-11-01
Authors: Yano, J., Jennings, A., Lam, B., Hoffman, I.D.
PDB entry 5tt8: Crystal structure of the complex of Helicobacter pylori alpha-carbonic anhydrase with benzolamide
Classification: LYASE
Source organism: Helicobacter pylori (strain ATCC 700392 / 26695)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2016-11-02
Authors: Modak, J.K., Roujeinikova, A.
PDB entry 5tta: A 1.85A X-Ray Structure from Peptoclostridium difficile 630 of a Hypothetical Protein
Classification: STRUCTURAL GENOMICS, UNKNOWN FUNCTION
Source organism: Peptoclostridium difficile
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2016-11-02
Authors: Brunzelle, J.S., Minasov, G., Shuvalova, L., Cordona-Correa, A., Dubrovska, I., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5ttb: Solution structure of apo ArCP from yersiniabactin synthetase
Classification: LIGASE
Source organism: Yersinia pestis
Experimental method: SOLUTION NMR
Deposited: 2016-11-02
Authors: Frueh, D.P., Goodrich, A.C.
PDB entry 5ttc: XFEL structure of influenza A M2 wild type TM domain at high pH in the lipidic cubic phase at room temperature
Classification: MEMBRANE PROTEIN
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2016-11-02
Authors: Thomaston, J.L., Woldeyes, R.A., Fraser, J.S., DeGrado, W.F.
PDB entry 5ttd: Minor pilin FctB from S. pyogenes with engineered intramolecular isopeptide bond
Classification: CELL ADHESION
Source organism: Escherichia coli; Streptococcus pyogenes
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2016-11-02
Authors: Young, P.G., Kwon, H., Squire, C.J., Baker, E.N.
PDB entry 5tte: Crystal Structure of an RBR E3 ubiquitin ligase in complex with an E2-Ub thioester intermediate mimic
Classification: LIGASE
Source organism: Homo sapiens; Triticum aestivum
Experimental method: X-RAY DIFFRACTION
Resolution: 3.501 Å
Deposited: 2016-11-03
Authors: Yuan, L., Lv, Z., Olsen, S.K.
PDB entry 5ttf: Crystal structure of catalytic domain of G9a with MS012
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.72 Å
Deposited: 2016-11-03
Authors: DONG, A., ZENG, H., LIU, J., XIONG, Y., BABAULT, N., JIN, J., TEMPEL, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., WU, H., BROWN, P.J., Structural Genomics Consortium (SGC)
PDB entry 5ttg: Crystal structure of catalytic domain of GLP with MS012
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.66 Å
Deposited: 2016-11-03
Authors: DONG, A., ZENG, H., LIU, J., XIONG, Y., BABAULT, N., JIN, J., TEMPEL, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., WU, H., BROWN, P.J., Structural Genomics Consortium (SGC)
PDB entry 5tth: Heterodimeric SpyCatcher/SpyTag-fused zebrafish TRAP1 in ATP/ADP-hybrid state
Classification: CHAPERONE
Source organism: Danio rerio; Streptococcus pyogenes
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2 Å
Deposited: 2016-11-03
Authors: Elnatan, D., Betegon, M., Liu, Y., Agard, D.A., Northeast Structural Genomics Consortium (NESG)
PDB entry 5ttj: Crystal Structure of Nicotine Oxidoreductase from Pseudomonas putida
Classification: OXIDOREDUCTASE
Source organism: Pseudomonas putida (strain S16)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2016-11-03
Authors: Tararina, M.A., Janda, K.D., Allen, K.N.
PDB entry 5ttk: Crystal Structure of Selenomethionine-incorporated Nicotine Oxidoreductase from Pseudomonas putida
Classification: OXIDOREDUCTASE
Source organism: Pseudomonas putida (strain S16)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.51 Å
Deposited: 2016-11-03
Authors: Tararina, M.A., Janda, K.D., Allen, K.N.
PDB entry 5tto: X-ray crystal structure of PPARgamma in complex with SR1643
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.246 Å
Deposited: 2016-11-04
Authors: Bruning, J.B., Frkic, R.L., Griffin, P., Kamenecka, T., Abell, A.
PDB entry 5ttp: Cryo-EM structure of MsbA-nanodisc with ADP-vanadate
Classification: HYDROLASE
Source organism: Escherichia coli O157:H7
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.8 Å
Deposited: 2016-11-04
Authors: Mi, W., Walz, T., Liao, M.
PDB entry 5ttr: LEU 55 PRO TRANSTHYRETIN CRYSTAL STRUCTURE
Classification: TRANSPORT
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 1998-04-30
Authors: Sebastiao, M.P., Saraiva, M.J., Damas, A.M.
PDB entry 5tts: Jak3 with covalent inhibitor 4
Classification: TRANSFERASE/TRANSFERASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.34 Å
Deposited: 2016-11-04
Authors: Vajdos, F.F.
PDB entry 5ttt: Sparse-restraint solution NMR structure of micelle-solubilized cytosolic amino terminal domain of C. elegans mechanosensory ion channel MEC-4 refined by restrained Rosetta
Classification: TRANSPORT PROTEIN
Source organism: Caenorhabditis elegans
Experimental method: SOLUTION NMR
Deposited: 2016-11-04
Authors: Everett, J.K., Liu, G., Mao, B., Driscoll, M.A., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
PDB entry 5ttu: Jak3 with covalent inhibitor 7
Classification: TRANSFERASE/TRANSFERASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.72 Å
Deposited: 2016-11-04
Authors: Vajdos, F.F.
PDB entry 5ttv: Jak3 with covalent inhibitor 6
Classification: TRANSFERASE/TRANSFERASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.93 Å
Deposited: 2016-11-04
Authors: Vajdos, F.F.
PDB entry 5ttw: Crystal Structure of EED in Complex with UNC4859
Classification: TRANSCRIPTION REGULATOR/INHIBITOR
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.74 Å
Deposited: 2016-11-04
Authors: The, J., Barnash, K.D., Brown, P.J., Edwards, A.M., Bountra, C., Frye, S.V., James, L.I., Arrowsmith, C.H.