LiteFold/PDB huggingface dataset:
PDB entry 4is4: The glutamine synthetase from the dicotyledonous plant M. truncatula is a decamer
Classification: LIGASE
Source organism: Medicago truncatula
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2013-01-16
Authors: Seabra, A.R., Carvalho, H., Pereira, P.J.B.
PDB entry 4is5: Crystal Structure of the ligand-free inactive Matriptase
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.48 Å
Deposited: 2013-01-16
Authors: Huang, M.D., Zhao, B.Y., Yuan, C., Li, R.
PDB entry 4is6: Crystal structure of HLA-DR4 bound to GP100 peptide
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2013-01-16
Authors: Li, Y.
PDB entry 4is7: Crystal Structure of the CASKIN2 SAM Domain Tandem
Classification: PROTEIN BINDING
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.751 Å
Deposited: 2013-01-16
Authors: Donaldson, L.W., Kwan, J.J.
PDB entry 4is8: Divergent sequence tunes ligand sensitivity in phospholipid-regulated hormone receptors
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.78 Å
Deposited: 2013-01-16
Authors: Musille, P.M., Pathak, M.C., Ortlund, E.A.
PDB entry 4is9: Crystal Structure of the Escherichia coli LpxC/L-161,240 complex
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.13 Å
Deposited: 2013-01-16
Authors: Lee, C.-J., Zhou, P.
PDB entry 4isa: Crystal Structure of the Escherichia coli LpxC/BB-78485 complex
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-01-16
Authors: Lee, C.-J., Zhou, P.
PDB entry 4isb: Crystal Structure of Apo Mtb FadD10
Classification: TRANSFERASE, LIGASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2013-01-16
Authors: Liu, Z., Wang, F., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
PDB entry 4isc: Crystal structure of a putative Methyltransferase from Pseudomonas syringae
Classification: TRANSFERASE
Source organism: Pseudomonas syringae pv. tomato
Experimental method: X-RAY DIFFRACTION
Resolution: 2.78 Å
Deposited: 2013-01-16
Authors: Filippova, E.V., Wawrzak, Z., Minasov, G., Shuvalova, L., Kiryukhina, O., Clancy, S., Joachimiak, A., Anderson, W.F., Midwest Center for Structural Genomics (MCSG)
PDB entry 4isd: Crystal structure of GLUTATHIONE TRANSFERASE homolog from BURKHOLDERIA GL BGR1, TARGET EFI-501803, with bound glutathione
Classification: TRANSFERASE
Source organism: Burkholderia glumae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.65 Å
Deposited: 2013-01-16
Authors: Vetting, M.W., Toro, R., Bhosle, R., Al Obaidi, N.F., Morisco, L.L., Wasserman, S.R., Sojitra, S., Washington, E., Scott Glenn, A., Chowdhury, S., Evans, B., Hammonds, J., Hillerich, B., Love, J., Seidel, R.D., Imker, H.J., Armstrong, R.N., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4ise: Human glucokinase in complex with novel activator (2S)-3-cyclohexyl-2-(6-fluoro-4-oxoquinazolin-3(4H)-yl)-N-(1,3-thiazol-2-yl)propanamide
Classification: TRANSFERASE/TRANSFERASE ACTIVATOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.78 Å
Deposited: 2013-01-16
Authors: Hosfield, D., Skene, R.J.
PDB entry 4isf: Human glucokinase in complex with novel activator (2S)-3-cyclohexyl-2-(6-fluoro-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)-N-(1,3-thiazol-2-yl)propanamide
Classification: TRANSFERASE/TRANSFERASE ACTIVATOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.09 Å
Deposited: 2013-01-16
Authors: Hosfield, D., Skene, R.J.
PDB entry 4isg: Human glucokinase in complex with novel activator (2S)-3-cyclohexyl-2-[4-(methylsulfonyl)-2-oxopiperazin-1-yl]-N-(1,3-thiazol-2-yl)propanamide
Classification: TRANSFERASE/TRANSFERASE ACTIVATOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.645 Å
Deposited: 2013-01-16
Authors: Hosfield, D., Skene, R.J.
PDB entry 4ish: Structure of FACTOR VIIA in complex with the inhibitor BMS-593214 also known as 2'-[(6R,6AR,11BR)-2-CARBAMIMIDOYL-6,6A,7,11B-TETRAHYDRO-5H-INDENO[2,1-C]QUINOLIN-6-YL]-5'-HYDROXY-4'-METHOXYBIPHENYL-4-CARBOXYLIC ACID
Classification: HYDROLASE/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.82 Å
Deposited: 2013-01-16
Authors: Wei, A.
PDB entry 4isi: Structure of FACTOR VIIA in complex with the inhibitor (6S)-N-(4-CARBAMIMIDOYLBENZYL)-1-CHLORO-3-(CYCLOBUTYLAMINO)-8,8-DIETHYL-4-OXO-4,6,7,8-TETRAHYDROPYRROLO[1,2-A]PYRAZINE-6-CARBOXAMIDE
Classification: HYDROLASE/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.94 Å
Deposited: 2013-01-16
Authors: Wei, A.
PDB entry 4isj: RNA Ligase RtcB in complex with Mn(II)
Classification: LIGASE
Source organism: Pyrococcus horikoshii
Experimental method: X-RAY DIFFRACTION
Resolution: 2.344 Å
Deposited: 2013-01-16
Authors: Desai, K.K., Bingman, C.A., Phillips Jr., G.N., Raines, R.T.
PDB entry 4isk: Crystal structure of E.coli thymidylate synthase with dUMP and the BGC 945 inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.752 Å
Deposited: 2013-01-16
Authors: Tochowicz, A., Finer-Moore, J., Stroud, R.M.
PDB entry 4isl: Crystal Structure of the inactive Matriptase in complex with its inhibitor HAI-1
Classification: hydrolase/hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.29 Å
Deposited: 2013-01-16
Authors: Huang, M.D., Zhao, B.Y., Yuan, C., Li, R.
PDB entry 4ism: Crystal structure of ferritin from Pseudo-nitzschia multiseries soaked with zinc
Classification: TRANSPORT PROTEIN
Source organism: Pseudo-nitzschia multiseries
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2013-01-16
Authors: Pfaffen, S., Murphy, M.E.P.
PDB entry 4isn: Crystal Structure of Matriptase in complex with its inhibitor HAI-1
Classification: hydrolase/hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.45 Å
Deposited: 2013-01-16
Authors: Huang, M.D., Zhao, B.Y., Yuan, C., Li, R.
PDB entry 4iso: Crystal Structure of Matriptase in complex with its inhibitor HAI-1
Classification: hydrolase/hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.01 Å
Deposited: 2013-01-16
Authors: Huang, M.D., Zhao, B.Y., Yuan, C., Li, R.
PDB entry 4isp: Crystal structure of iron soaked (4h) ferritin from Pseudo-nitzschia multiseries
Classification: TRANSPORT PROTEIN
Source organism: Pseudo-nitzschia multiseries
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2013-01-17
Authors: Pfaffen, S., Murphy, M.E.P.
PDB entry 4isq: Binding domain of Botulinum neurotoxin DC in complex with human synaptotagmin I
Classification: TOXIN
Source organism: Clostridium botulinum; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.65 Å
Deposited: 2013-01-17
Authors: Berntsson, R.P.-A., Peng, L., Svensson, L.M., Dong, M., Stenmark, P.
PDB entry 4isr: Binding domain of Botulinum neurotoxin DC in complex with rat synaptotagmin II
Classification: TOXIN
Source organism: Clostridium botulinum; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.59 Å
Deposited: 2013-01-17
Authors: Berntsson, R.P.-A., Peng, L., Svensson, L.M., Dong, M., Stenmark, P.
PDB entry 4iss: SeMet-substituted Kluyveromyces lactis Allophanate Hydrolase
Classification: HYDROLASE
Source organism: Kluyveromyces lactis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2013-01-17
Authors: Fan, C., Xiang, S.
PDB entry 4ist: S177A Kluyveromyces lactis Allophanate Hydrolase
Classification: HYDROLASE
Source organism: Kluyveromyces lactis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2013-01-17
Authors: Fan, C., Xiang, S.
PDB entry 4isu: Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the antagonist (2R)-IKM-159 at 2.3A resolution.
Classification: membrane protein/antagonist
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2013-01-17
Authors: Juknaite, L., Frydenvang, K., Kastrup, J.S.
PDB entry 4isv: Crystal structure of the Fab FRAGMENT OF 1C2, A MONOCLONAL ANTIBODY SPECIFIC FOR POLY-GLUTAMINE
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.497 Å
Deposited: 2013-01-17
Authors: Klein, F.A.C., Zeder-Lutz, G., Cousido-Siah, A., Mitschler, A., Katz, A., Eberling, P., Mandel, J.L., Podjarny, A., Trottier, Y.
PDB entry 4isw: Crystal Structure of Phosphorylated C.elegans Thymidylate Synthase in Complex with dUMP
Classification: TRANSFERASE
Source organism: Caenorhabditis elegans
Experimental method: X-RAY DIFFRACTION
Resolution: 3.14 Å
Deposited: 2013-01-17
Authors: Wilk, P., Dowiercial, A., Banaszak, K., Jarmula, A., Rypniewski, W., Rode, W.
PDB entry 4isx: The crystal structure of maltose o-acetyltransferase from clostridium difficile 630 in complex with acetyl-coa
Classification: TRANSFERASE
Source organism: Clostridium difficile
Experimental method: X-RAY DIFFRACTION
Resolution: 2.702 Å
Deposited: 2013-01-17
Authors: Tan, K., Gu, G., Peterson, S., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4isy: Crystal structure of IscS from Mycobacterium tuberculosis
Classification: TRANSFERASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.59 Å
Deposited: 2013-01-17
Authors: Rybniker, J., Pojer, F., Cole, S.T.
PDB entry 4isz: RNA ligase RtcB in complex with GTP alphaS and Mn(II)
Classification: LIGASE
Source organism: Pyrococcus horikoshii
Experimental method: X-RAY DIFFRACTION
Resolution: 2.303 Å
Deposited: 2013-01-17
Authors: Desai, K.K., Bingman, C.A., Phillips Jr., G.N., Raines, R.T.
PDB entry 4it0: Structure of the RNA ligase RtcB-GMP/Mn(II) complex
Classification: LIGASE
Source organism: Pyrococcus horikoshii
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2013-01-17
Authors: Desai, K.K., Bingman, C.A., Phillips Jr., G.N., Raines, R.T.
PDB entry 4it1: Crystal structure of enolase pfl01_3283 (target efi-502286) from pseudomonas fluorescens pf0-1 with bound magnesium, potassium and tartrate
Classification: ISOMERASE
Source organism: Pseudomonas fluorescens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2013-01-17
Authors: Patskovsky, Y., Toro, R., Bhosle, R., Hillerich, B., Seidel, R.D., Washington, E., Scott Glenn, A., Chowdhury, S., Evans, B., Hammonds, J., Zencheck, W.D., Imker, H.J., Al Obaidi, N., Stead, M., Love, J., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4it2: Mn(III)-PPIX bound Tt H-NOX
Classification: OXYGEN BINDING
Source organism: Caldanaerobacter subterraneus subsp. tengcongensis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.097 Å
Deposited: 2013-01-17
Authors: Winter, M.B., Klemm, P.J., Phillips-Piro, C.M., Raymond, K.M., Marletta, M.A.
PDB entry 4it3: Crystal Structure of Iml3 from S. cerevisiae
Classification: CELL CYCLE
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.495 Å
Deposited: 2013-01-17
Authors: Hinshaw, S.M., Harrison, S.C.
PDB entry 4it4: Crystal structure of residues 1-211 of CG17282
Classification: UNKNOWN FUNCTION
Source organism: Drosophila melanogaster
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2013-01-17
Authors: Agyekum, B., Bouyain, S.
PDB entry 4it5: Chaperone HscB from Vibrio cholerae
Classification: CHAPERONE
Source organism: Vibrio cholerae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.152 Å
Deposited: 2013-01-17
Authors: Osipiuk, J., Gu, M., Papazisi, L., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4it6: Crystal structure of amino acid residues 1-120 of CG17282
Classification: UNKNOWN FUNCTION
Source organism: Drosophila melanogaster
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2013-01-17
Authors: Bouyain, S., Agyekum, B., Hall, D.R.
PDB entry 4it7: Crystal structure of Al-CPI
Classification: HYDROLASE INHIBITOR
Source organism: Ascaris lumbricoides
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2013-01-17
Authors: Mei, G.Q., Liu, S.L., Sun, M.Z., Liu, J.
PDB entry 4it8: A sperm whale myoglobin mutant L29H Mb with two distal histidines
Classification: OXYGEN STORAGE
Source organism: Physeter catodon
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2013-01-18
Authors: Lin, Y.-W., Tan, X.-S., Li, W., Sun, M.-H., Wen, G.-B., Liu, J.-H.
PDB entry 4it9: Structure of Bacterial Enzyme
Classification: OXIDOREDUCTASE
Source organism: Synechococcus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2013-01-18
Authors: Rhee, S., Park, J.
PDB entry 4ita: Structure of bacterial enzyme in complex with cofactor
Classification: OXIDOREDUCTASE
Source organism: Synechococcus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2013-01-18
Authors: Rhee, S., Park, J.
PDB entry 4itb: Structure of bacterial enzyme in complex with cofactor and substrate
Classification: oxidoreductase/substrate
Source organism: Synechococcus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2013-01-18
Authors: Rhee, S., Park, J.
PDB entry 4itc: Crystal Structure Analysis of the K1 Cleaved Adhesin domain of Lys-gingipain (Kgp) from Porphyromonas gingivalis W83
Classification: HYDROLASE
Source organism: Porphyromonas gingivalis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2013-01-18
Authors: Ganuelas, L.A., Li, N., Hunter, N., Collyer, C.A.
PDB entry 4itd: Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing transition mutation
Classification: DNA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.94 Å
Deposited: 2013-01-18
Authors: Zhang, F., Suzuki, K., Tsunoda, M., Wilkinson, O., Millington, C.L., Williams, D.M., Morishita, E.C., Takenaka, A.
PDB entry 4ite: Crystal structure of the human vitamin D receptor ligand binding domain complexed with 1alpha,25-Dihydroxy-2alpha-[2-(2H-tetrazol-2-yl)ethyl]vitamin D3
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.49 Å
Deposited: 2013-01-18
Authors: Kakuda, S., Takimoto-Kamimura, M.
PDB entry 4itf: Crystal structure of the human vitamin D receptor ligand binding domain complexed with 1alpha,25-Dihydroxy-2alpha-[2-(1H-tetrazole-1-yl)ethyl]vitamin D3
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.84 Å
Deposited: 2013-01-18
Authors: Kakuda, S., Takimoto-Kamimura, M.
PDB entry 4itg: P113S mutant of E. coli Cystathionine beta-lyase MetC
Classification: LYASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.74 Å
Deposited: 2013-01-18
Authors: Squire, C.J., Yosaatmadja, Y., Soo, V.W.C., Patrick, W.M.
PDB entry 4ith: Crystal structure of RIP1 kinase in complex with necrostatin-1 analog
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2013-01-18
Authors: Xie, T., Peng, W., Liu, Y., Yan, C., Shi, Y.
PDB entry 4iti: Crystal structure of RIP1 kinase in complex with necrostatin-3 analog
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.86 Å
Deposited: 2013-01-18
Authors: Xie, T., Peng, W., Liu, Y., Yan, C., Shi, Y.
PDB entry 4itj: Crystal structure of RIP1 kinase in complex with necrostatin-4
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-01-18
Authors: Xie, T., Peng, W., Liu, Y., Yan, C., Shi, Y.
PDB entry 4itk: The structure of C.reinhardtii Ferredoxin 2
Classification: ELECTRON TRANSPORT
Source organism: Chlamydomonas reinhardtii
Experimental method: X-RAY DIFFRACTION
Resolution: 1.18 Å
Deposited: 2013-01-18
Authors: Alahuhta, P.M., Lunin, V.V.
PDB entry 4itl: Crystal structure of LpxK from Aquifex aeolicus in complex with AMP-PCP at 2.1 angstrom resolution
Classification: TRANSFERASE
Source organism: Aquifex aeolicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.09 Å
Deposited: 2013-01-18
Authors: Emptage, R.P., Pemble IV, C.W., York, J.D., Raetz, C.R.H., Zhou, P.
PDB entry 4itm: Crystal structure of "apo" form LpxK from Aquifex aeolicus in complex with ATP at 2.2 angstrom resolution
Classification: TRANSFERASE
Source organism: Aquifex aeolicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1994 Å
Deposited: 2013-01-18
Authors: Emptage, R.P., Pemble IV, C.W., York, J.D., Raetz, C.R.H., Zhou, P.
PDB entry 4itn: Crystal structure of "compact P-loop" LpxK from Aquifex aeolicus in complex with chloride at 2.2 angstrom resolution
Classification: TRANSFERASE
Source organism: Aquifex aeolicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1912 Å
Deposited: 2013-01-18
Authors: Emptage, R.P., Pemble IV, C.W., York, J.D., Raetz, C.R.H., Zhou, P.
PDB entry 4ito: Human CA II inhibition by novel sulfonamide
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.162 Å
Deposited: 2013-01-18
Authors: Aggarwal, M., McKenna, R.
PDB entry 4itp: Structure of human carbonic anhydrase II bound to a benzene sulfonamide
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.697 Å
Deposited: 2013-01-18
Authors: Biswas, S., McKenna, R.
PDB entry 4itq: Crystal structure of hypothetical protein SCO1480 bound to DNA
Classification: GENE REGULATION, STRUCTURAL PROTEIN/DNA
Source organism: Streptomyces coelicolor; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2013-01-18
Authors: Guarne, A., Nanji, T., Gloyd, M., Swiercz, J.P., Elliot, M.A.
PDB entry 4itr: Crystal Structure of IbpAFic2-H3717A in complex with adenylylated Cdc42
Classification: TRANSFERASE
Source organism: Haemophilus somnus; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2013-01-18
Authors: Xiao, J., Dixon, J.E.
PDB entry 4its: Crystal structure of the catalytic domain of human Pus1 with MES in the active site
Classification: RNA BINDING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2013-01-18
Authors: Czudnochowski, N., Finer-Moore, J.S., Stroud, R.M.
PDB entry 4itt: Crystal structure of iron soaked (5 min) ferritin from Pseudo-nitzschia multiseries
Classification: TRANSPORT PROTEIN
Source organism: Pseudo-nitzschia multiseries
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2013-01-18
Authors: Pfaffen, S., Murphy, M.E.P.
PDB entry 4itu: Crystal structure of S-2-HYDROXYPROPYL COENZYME M DEHYDROGENASE (S-HPCDH) bound to S-HPC AND NADH
Classification: OXIDOREDUCTASE
Source organism: Xanthobacter autotrophicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2013-01-18
Authors: Bakelar, J.W., Johnson, S.J.
PDB entry 4itv: Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, P212121 form
Classification: OXIDOREDUCTASE
Source organism: Influenza A virus; Streptomyces aureofaciens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.598 Å
Deposited: 2013-01-18
Authors: Lai, Y.-T., Sawaya, M.R., Yeates, T.O.
PDB entry 4itw: Anaerobic crystal structure of iron soaked (75 min) ferritin from Pseudo-nitzschia multiseries
Classification: TRANSPORT PROTEIN
Source organism: Pseudo-nitzschia multiseries
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2013-01-18
Authors: Pfaffen, S., Murphy, M.E.P.
PDB entry 4itx: P113S mutant of E. coli Cystathionine beta-lyase MetC inhibited by reaction with L-Ala-P
Classification: LYASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.61 Å
Deposited: 2013-01-19
Authors: Squire, C.J., Yosaatmadja, Y., Soo, V.W.C., Patrick, W.M.
PDB entry 4ity: Crystal structure of Leishmania mexicana arginase
Classification: HYDROLASE
Source organism: Leishmania mexicana
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-01-19
Authors: D'Antonio, E.L., Ullman, B., Roberts, S.C., Gaur Dixit, U., Wilson, M.E., Hai, Y., Christianson, D.W.
PDB entry 4itz: Crystal structure of the FK506 binding domain of Plasmodium vivax FKBP35 in complex with a tetrapeptide substrate
Classification: ISOMERASE/SUBSTRATE
Source organism: Plasmodium vivax; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2013-01-19
Authors: Sreekanth, R., Yoon, H.S.
PDB entry 4iu0: Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABH
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Leishmania mexicana
Experimental method: X-RAY DIFFRACTION
Resolution: 1.77 Å
Deposited: 2013-01-19
Authors: D'Antonio, E.L., Ullman, B., Roberts, S.C., Gaur Dixit, U., Wilson, M.E., Hai, Y., Christianson, D.W.
PDB entry 4iu1: Crystal structure of Leishmania mexicana arginase in complex with inhibitor nor-NOHA
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Leishmania mexicana
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2013-01-19
Authors: D'Antonio, E.L., Ullman, B., Roberts, S.C., Gaur Dixit, U., Wilson, M.E., Hai, Y., Christianson, D.W.
PDB entry 4iu2: Cohesin-dockerin -X domain complex from Ruminococcus flavefacience
Classification: STRUCTURAL PROTEIN
Source organism: Ruminococcus flavefaciens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.001 Å
Deposited: 2013-01-19
Authors: Salama-Alber, O., Bayer, E., Frolow, F.
PDB entry 4iu3: Cohesin-dockerin -X domain complex from Ruminococcus flavefacience
Classification: STRUCTURAL PROTEIN
Source organism: Ruminococcus flavefaciens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.97 Å
Deposited: 2013-01-19
Authors: Salama-Alber, O., Bayer, E., Frolow, F.
PDB entry 4iu4: Crystal structure of Leishmania mexicana arginase in complex with inhibitor BEC
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Leishmania mexicana
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-01-19
Authors: D'Antonio, E.L., Ullman, B., Roberts, S.C., Gaur Dixit, U., Wilson, M.E., Hai, Y., Christianson, D.W.
PDB entry 4iu5: Crystal structure of Leishmania mexicana arginase in complex with catalytic product L-ornithine
Classification: HYDROLASE
Source organism: Leishmania mexicana
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2013-01-19
Authors: D'Antonio, E.L., Ullman, B., Roberts, S.C., Gaur Dixit, U., Wilson, M.E., Hai, Y., Christianson, D.W.
PDB entry 4iu6: Human Methionine Aminopeptidase in complex with FZ1: Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1
Classification: hydrolase/hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2013-01-19
Authors: Gabelli, S.B., Zhang, F., Miller, M., Liu, J., Amzel, L.M.
PDB entry 4iu7: Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with Constrained WAY-derivative, 2b
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.29 Å
Deposited: 2013-01-20
Authors: Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 4iu8: Crystal structure of a membrane transporter (selenomethionine derivative)
Classification: TRANSPORT PROTEIN
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 3.11 Å
Deposited: 2013-01-20
Authors: Yan, H., Huang, W., Yan, C., Gong, X., Jiang, S., Zhao, Y., Wang, J., Shi, Y.
PDB entry 4iu9: Crystal structure of a membrane transporter
Classification: TRANSPORT PROTEIN
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 3.005 Å
Deposited: 2013-01-20
Authors: Yan, H., Huang, W., Yan, C., Gong, X., Jiang, S., Zhao, Y., Wang, J., Shi, Y.
PDB entry 4iua: Crystal Structure of the NK2 Fragment (31-290) of the mouse Hepatocyte Growth Factor/Scatter Factor
Classification: HORMONE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.05 Å
Deposited: 2013-01-20
Authors: Tolbert, W.D., Zhou, E., Kovach, A., Melcher, K., Xu, H.E.
PDB entry 4iub: Crystal structure of an O2-tolerant [NiFe]-hydrogenase from Ralstonia eutropha in its as-isolated form - oxidized state 1
Classification: OXIDOREDUCTASE
Source organism: Ralstonia eutropha
Experimental method: X-RAY DIFFRACTION
Resolution: 1.61 Å
Deposited: 2013-01-20
Authors: Frielingsdorf, S., Schmidt, A., Fritsch, J., Lenz, O., Scheerer, P.
PDB entry 4iuc: Crystal structure of an O2-tolerant [NiFe]-hydrogenase from Ralstonia eutropha in its as-isolated form - oxidized state 2
Classification: OXIDOREDUCTASE
Source organism: Ralstonia eutropha
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2013-01-20
Authors: Frielingsdorf, S., Schmidt, A., Fritsch, J., Lenz, O., Scheerer, P.
PDB entry 4iud: Crystal structure of an O2-tolerant [NiFe]-hydrogenase from Ralstonia eutropha in its as-isolated form with ascorbate - partly reduced state
Classification: OXIDOREDUCTASE
Source organism: Ralstonia eutropha
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2013-01-20
Authors: Hammer, M., Schmidt, A., Frielingsdorf, S., Fritsch, J., Lenz, O., Scheerer, P.
PDB entry 4iue: Tankyrase in complex with 7-(2-fluorophenyl)-4-methyl-1,2-dihydroquinolin-2-one
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.38 Å
Deposited: 2013-01-21
Authors: Jansson, A.E., Larsson, E.A., Nordlund, P.L.
PDB entry 4iuf: Crystal Structure of Human TDP-43 RRM1 Domain in Complex with a Single-stranded DNA
Classification: TRANSCRIPTION REGULATOR/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.752 Å
Deposited: 2013-01-21
Authors: Kuo, P.H., Doudeva, L.G., Wang, Y.T., Yang, W.Z., Yuan, H.S.
PDB entry 4iug: Crystal structure of beta-galactosidase from Aspergillus oryzae in complex with galactose
Classification: HYDROLASE
Source organism: Aspergillus oryzae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2013-01-21
Authors: Maksimainen, M., Rouvinen, J.
PDB entry 4iuh: Crystal structure of NreA of Staphylococcus carnosus with bound iodide
Classification: Nitrate-binding protein
Source organism: Staphylococcus carnosus subsp. carnosus TM300
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1971 Å
Deposited: 2013-01-21
Authors: Stehle, T., Niemann, V.
PDB entry 4iui: Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with Dynamic WAY derivative, 4a
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2013-01-21
Authors: Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 4iuj: Structure of Polymerase acid protein (PA) from Influenzavirus A Influenza A virus A, WILSON-SMITH/1933 (H1N1)
Classification: TRANSCRIPTION
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2013-01-21
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 4iuk: Crystal structure of NreA of Staphylococcus carnosus with bound nitrate
Classification: Nitrate-binding protein
Source organism: Staphylococcus carnosus subsp. carnosus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2013-01-21
Authors: Stehle, T., Niemann, V.
PDB entry 4iul: MIF4G domain of DAP5
Classification: TRANSLATION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2013-01-21
Authors: Frank, F., Virgili, G., Feoktistova, K., Sawicki, M., Sonenberg, N., Fraser, C., Nagar, B.
PDB entry 4ium: Equine arteritis virus papain-like protease 2 (PLP2) covalently bound to ubiquitin
Classification: HYDROLASE/PROTEIN BINDING
Source organism: Equine arteritis virus; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2013-01-21
Authors: Bailey-Elkin, B.A., James, T.W., Mark, B.L.
PDB entry 4iun: Crystal structure of Staphylococcal nuclease variant Delta+PHS R126E at cryogenic temperature
Classification: HYDROLASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2013-01-21
Authors: Bell-Upp, P.C., Schlessman, J.L., Garcia-Moreno E., B.
PDB entry 4iuo: 1.8 Angstrom Crystal Structure of the Salmonella enterica 3-Dehydroquinate Dehydratase (aroD) K170M Mutant in Complex with Quinate
Classification: LYASE
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-01-21
Authors: Light, S.H., Minasov, G., Duban, M.-E., Shuvalova, L., Kwon, K., Lavie, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4iup: crystal structure of Se-substituted arabidopsis thaliana SHH1 SAWADEE domain L200M/L218M mutant
Classification: GENE REGULATION
Source organism: Arabidopsis thaliana
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2013-01-21
Authors: Du, J., Patel, D.J.
PDB entry 4iuq: crystal structure of SHH1 SAWADEE domain
Classification: GENE REGULATION
Source organism: Arabidopsis thaliana
Experimental method: X-RAY DIFFRACTION
Resolution: 2.809 Å
Deposited: 2013-01-21
Authors: Du, J., Patel, D.J.
PDB entry 4iur: crystal structure of SHH1 SAWADEE domain in complex with H3K9me3 peptide
Classification: GENE REGULATION
Source organism: Arabidopsis thaliana; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.501 Å
Deposited: 2013-01-21
Authors: Patel, D.J., Du, J.
PDB entry 4ius: GCN5-related N-acetyltransferase from Kribbella flavida.
Classification: TRANSFERASE
Source organism: Kribbella flavida
Experimental method: X-RAY DIFFRACTION
Resolution: 1.3 Å
Deposited: 2013-01-21
Authors: Osipiuk, J., Chhor, G., Endres, M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 4iut: crystal structure of SHH1 SAWADEE domain in complex with H3K9me2 peptide
Classification: GENE REGULATION
Source organism: Arabidopsis thaliana; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2013-01-21
Authors: Du, J., Patel, D.J.
PDB entry 4iuu: Crystal structure of SHH1 SAWADEE domain in complex with H3K9me1 peptide
Classification: GENE REGULATION
Source organism: Arabidopsis thaliana; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2013-01-21
Authors: Du, J., Patel, D.J.
PDB entry 4iuv: crystal structure of SHH1 SAWADEE domain in complex with H3K4me1K9me1 peptide
Classification: GENE REGULATION
Source organism: Arabidopsis thaliana; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2013-01-21
Authors: Du, J., Patel, D.J.
PDB entry 4iuw: Crystal structure of PEPO from Lactobacillus rhamnosis HN001 (DR20)
Classification: HYDROLASE
Source organism: Lactobacillus rhamnosus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2013-01-21
Authors: Anderson, B.F., Knapp, K.M., Holland, R., Norris, G.E., Christensson, C., Bratt, H., Collins, L.J., Coolbear, T., Lubbers, M.W., Toole, P.W.O., Reid, J.R., Jameson, G.B.
PDB entry 4iuy: Crystal structure of short-chain dehydrogenase/reductase (apo-form) from A. baumannii clinical strain WM99C
Classification: OXIDOREDUCTASE
Source organism: Acinetobacter baumannii
Experimental method: X-RAY DIFFRACTION
Resolution: 2.385 Å
Deposited: 2013-01-21
Authors: Shah, B.S., Tetu, S.G., Harrop, S.J., Paulsen, I.T., Mabbutt, B.C.
PDB entry 4iuz: High resolution crystal structure of racemic ester insulin
Classification: HORMONE PRECURSOR
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2013-01-22
Authors: Avital-Shmilovici, M., Mandal, K., Gates, Z.P., Phillips, N., Weiss, M.A., Kent, S.B.H.
PDB entry 4iv0: Crystal structure of N-methyl transferase from Plasmodium vivax complexed with S-adenosyl methionine and phosphate
Classification: TRANSFERASE
Source organism: Plasmodium vivax
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2013-01-22
Authors: Lukk, T., Nair, S.K.
PDB entry 4iv1: Crystal structure of recombinant foot-and-mouth-disease virus A22 empty capsid
Classification: VIRUS
Source organism: Foot-and-mouth disease virus - type A
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2013-01-22
Authors: Porta, C., Kotecha, A., Burman, A., Jackson, T., Ren, J., Loureiro, S., Jones, I.M., Fry, E.E., Stuart, D.I., Charleston, B.
PDB entry 4iv2: Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with Dynamic WAY-derivative, 5a
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.14 Å
Deposited: 2013-01-22
Authors: Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 4iv3: Crystal structure of recombinant foot-and-mouth-disease virus A22-H2093C empty capsid
Classification: VIRUS
Source organism: Foot-and-mouth disease virus - type A
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2013-01-22
Authors: Porta, C., Kotecha, A., Burman, A., Jackson, T., Ren, J., Loureiro, S., Jones, I.M., Fry, E.E., Stuart, D.I., Charleston, B.
PDB entry 4iv4: Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with Constrained WAY-derivative, 5b
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2013-01-22
Authors: Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 4iv5: X-ray crystal structure of a putative aspartate carbamoyltransferase from Trypanosoma cruzi
Classification: TRANSFERASE
Source organism: Trypanosoma cruzi
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2013-01-22
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 4iv6: X-ray crystal structure of an isovaleryl-CoA dehydrogenase from Mycobacterium smegmatis
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium smegmatis
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2013-01-22
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 4iv8: Crystal structure of N-methyl transferase from Plasmodium knowlesi complexed with S-adenosyl methionine
Classification: TRANSFERASE
Source organism: Plasmodium knowlesi
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2013-01-22
Authors: Lukk, T., Nair, S.K.
PDB entry 4iv9: Structure of the Flavoprotein Tryptophan-2-Monooxygenase
Classification: OXIDOREDUCTASE
Source organism: Pseudomonas savastanoi
Experimental method: X-RAY DIFFRACTION
Resolution: 1.951 Å
Deposited: 2013-01-22
Authors: Gaweska, H.M., Taylor, A.B., Hart, P.J., Fitzpatrick, P.F.
PDB entry 4iva: JAK2 kinase (JH1 domain) in complex with the inhibitor TRANS-4-[(8AS)-2-[(1R)-1-HYDROXYETHYL]IMIDAZO[4,5-D]PYRROLO[2,3-B]PYRIDIN-1(8AH)-YL]CYCLOHEXANECARBONITRILE
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2013-01-22
Authors: Eigenbrot, C., Shia, S.
PDB entry 4ivb: JAK1 kinase (JH1 domain) in complex with the inhibitor TRANS-4-{2-[(1R)-1-HYDROXYETHYL]IMIDAZO[4,5-D]PYRROLO[2,3-B]PYRIDIN-1(6H)-YL}CYCLOHEXANECARBONITRILE
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2013-01-22
Authors: Eigenbrot, C., Steffek, M.
PDB entry 4ivc: JAK1 kinase (JH1 domain) in complex with the inhibitor (TRANS-4-{2-[(1R)-1-HYDROXYETHYL]IMIDAZO[4,5-D]PYRROLO[2,3-B]PYRIDIN-1(6H)-YL}CYCLOHEXYL)ACETONITRILE
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2013-01-22
Authors: Eigenbrot, C., Shia, S.
PDB entry 4ivd: JAK1 kinase (JH1 domain) in complex with compound 34
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.93 Å
Deposited: 2013-01-22
Authors: Eigenbrot, C., Steffek, M.
PDB entry 4ive: Crystal structure of a polyadenylate-binding protein 3 (PABPC3) from Homo sapiens at 2.30 A resolution
Classification: RNA BINDING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2013-01-22
Authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
PDB entry 4ivf: Crystal structure of glutathione transferase homolog from Lodderomyces elongisporus, target EFI-501753, with two GSH per subunit
Classification: TRANSFERASE
Source organism: Lodderomyces elongisporus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2013-01-22
Authors: Vetting, M.W., Toro, R., Bhosle, R., Al Obaidi, N.F., Morisco, L.L., Wasserman, S.R., Sojitra, S., Washington, E., Scott Glenn, A., Chowdhury, S., Evans, B., Hammonds, J., Hillerich, B., Love, J., Seidel, R.D., Imker, H.J., Armstrong, R.N., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4ivg: Crystal structure of mitochondrial Hsp90 (TRAP1) NTD-Middle domain dimer with AMPPNP
Classification: CHAPERONE
Source organism: Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 1.749 Å
Deposited: 2013-01-22
Authors: Partridge, J.R., Lavery, L.A., Agard, D.A.
PDB entry 4ivh: Crystal structure of QKLVFFAED nonapeptide segment from amyloid beta incorporated into a macrocyclic beta-sheet template
Classification: DE NOVO PROTEIN
Experimental method: X-RAY DIFFRACTION
Resolution: 1.77 Å
Deposited: 2013-01-22
Authors: Pham, J.D., Chim, N., Goulding, C.W., Nowick, J.S.
PDB entry 4ivi: Crystal structure of a family VIII carboxylesterase.
Classification: HYDROLASE
Source organism: uncultured bacterium
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2013-01-23
Authors: An, Y.J., Kim, M.-K., Jeong, C.-S., Cha, S.-S.
PDB entry 4ivj: Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, I222 form
Classification: OXIDOREDUCTASE
Source organism: Influenza A virus; Streptomyces aureofaciens
Experimental method: X-RAY DIFFRACTION
Resolution: 7.351 Å
Deposited: 2013-01-23
Authors: Lai, Y.-T., Sawaya, M.R., Yeates, T.O.
PDB entry 4ivk: Crystal structure of a fammily VIII carboxylesterase in a complex with cephalothin.
Classification: HYDROLASE
Source organism: uncultured bacterium
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-01-23
Authors: An, Y.J., Kim, M.-K., Jeong, C.-S., Cha, S.-S.
PDB entry 4ivm: Structure of human protoporphyrinogen IX oxidase(R59G)
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.769 Å
Deposited: 2013-01-23
Authors: Xiaohong, Q., Baifan, W.
PDB entry 4ivn: The Vibrio vulnificus NanR protein complexed with ManNAc-6P
Classification: TRANSCRIPTION REGULATOR
Source organism: Vibrio vulnificus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2013-01-23
Authors: Hwang, J., Kim, M.H.
PDB entry 4ivo: Structure of human protoporphyrinogen IX oxidase(R59Q)
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.597 Å
Deposited: 2013-01-23
Authors: Xiaohong, Q., Baifan, W.
PDB entry 4ivp: Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with IN51/20
Classification: TRANSFERASE
Source organism: Human herpesvirus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2013-01-23
Authors: Pernot, L., Novakovic, I., Westermaier, Y., Perozzo, R., Raic-Malic, S., Scapozza, L.
PDB entry 4ivq: Crystal structure of thymidine kinase from Herpes simplex virus type 1 in complex with IN43/5
Classification: TRANSFERASE
Source organism: Human herpesvirus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2013-01-23
Authors: Pernot, L., Novakovic, I., Westermaier, Y., Perozzo, R., Raic-Malic, S., Scapozza, L.
PDB entry 4ivr: Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with IN52/10
Classification: TRANSFERASE
Source organism: Human herpesvirus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2013-01-23
Authors: Pernot, L., Novakovic, I., Westermaier, Y., Perozzo, R., Raic-Malic, S., Scapozza, L.
PDB entry 4ivs: Crystal structure of BACE1 with its inhibitor
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.636 Å
Deposited: 2013-01-23
Authors: Chen, T.T., Li, L., Chen, W.Y., Xu, Y.C.
PDB entry 4ivt: Crystal structure of BACE1 with its inhibitor
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2013-01-23
Authors: Chen, T.T., Li, L., Chen, W.Y., Xu, Y.C.
PDB entry 4ivv: Catalytic amidase domain of the major autolysin LytA from Streptococcus pneumaniae
Classification: HYDROLASE
Source organism: Streptococcus pneumoniae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.05 Å
Deposited: 2013-01-23
Authors: Sandalova, T., Achour, A.
PDB entry 4ivw: Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with Constrained WAY-derivative, 6b
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.06 Å
Deposited: 2013-01-23
Authors: Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 4ivy: Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with Dynamic WAY-derivative, 7a
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2013-01-23
Authors: Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 4ivz: A Y37F mutant of C.Esp1396I bound to its highest affinity operator site OM
Classification: TRANSCRIPTION/DNA
Source organism: Enterobacter sp.; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1 Å
Deposited: 2013-01-23
Authors: Martin, R.N.A., McGeehan, J.E., Kneale, G.G.
PDB entry 4iw0: Crystal structure and mechanism of activation of TBK1
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 4 Å
Deposited: 2013-01-23
Authors: Larabi, A., Devos, J.M., Ng, S.-L., Nanao, M.H., Round, A., Maniatis, T., Panne, D.
PDB entry 4iw1: HSA-fructose complex
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.56 Å
Deposited: 2013-01-23
Authors: Wang, Y., Yu, H., Shi, X., Huang, M.
PDB entry 4iw2: HSA-glucose complex
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.41 Å
Deposited: 2013-01-23
Authors: Wang, Y., Yu, H., Shi, X., Luo, Z., Huang, M.
PDB entry 4iw3: Crystal structure of a Pseudomonas putida prolyl-4-hydroxylase (P4H) in complex with elongation factor Tu (EF-Tu)
Classification: METAL BINDING PROTEIN/TRANSLATION
Source organism: Pseudomonas putida
Experimental method: X-RAY DIFFRACTION
Resolution: 2.697 Å
Deposited: 2013-01-23
Authors: Scotti, J.S., McDonough, M.A., Schofield, C.J.
PDB entry 4iw4: Crystal structure of the serine protease domain of MASP-3 in complex with ecotin
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Escherichia coli; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2 Å
Deposited: 2013-01-23
Authors: Gaboriaud, C.
PDB entry 4iw6: Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with Constrained WAY-derivative, 7b
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2013-01-23
Authors: Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 4iw7: Crystal structure of 8-amino-7-oxononanoate synthase (bioF) from Francisella tularensis.
Classification: TRANSFERASE
Source organism: Francisella tularensis subsp. tularensis SCHU S4
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2013-01-23
Authors: Newcomb, W., Niedzialkowska, E., Porebski, P.J., Grimshaw, S., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4iw8: Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with Dynamic WAY-derivative, 9a
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.0375 Å
Deposited: 2013-01-23
Authors: Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 4iw9: Crystal structure of glutathione s-transferase mha_0454 (target efi-507015) from mannheimia haemolytica, gsh complex
Classification: TRANSFERASE
Source organism: Mannheimia haemolytica PHL213
Experimental method: X-RAY DIFFRACTION
Resolution: 1.76 Å
Deposited: 2013-01-23
Authors: Patskovsky, Y., Toro, R., Bhosle, R., Hillerich, B., Seidel, R.D., Washington, E., Scott Glenn, A., Chowdhury, S., Evans, B., Hammonds, J., Zencheck, W.D., Imker, H.J., Al Obaidi, N., Stead, M., Love, J., Gerlt, J.A., Armstrong, R.N., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4iwb: Novel Fold of FliC/FliS Fusion Protein
Classification: MOTOR PROTEIN
Source organism: Aquifex aeolicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2013-01-23
Authors: Faham, S.
PDB entry 4iwc: Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with a Dynamic Thiophene-derivative
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.24 Å
Deposited: 2013-01-23
Authors: Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 4iwd: Structure of dually phosphorylated c-MET receptor kinase in complex with an MK-8033 analog
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.99 Å
Deposited: 2013-01-23
Authors: Soisson, S.M., Northrup, A., Rickert, K., Patel, S., Allison, T.
PDB entry 4iwf: Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with a Dynamic Oxime-derivative
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.932 Å
Deposited: 2013-01-23
Authors: Nwachukwu, J.C., Srinivasan, S., Parent, A.A., Cavett, V., Nowak, J., Hughes, T.S., Kojetin, D.J., Katzenellenbogen, J.A., Nettles, K.W.