LiteFold/PDB huggingface dataset:
PDB entry 6bcs: LilrB2 D1D2 domains complexed with benzamidine
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2017-10-20
Authors: Cao, Q., Sawaya, M.R., Eisenberg, D.S.
PDB entry 6bct: I-LtrI E184D bound to non-cognate C4 substrate (pre-cleavage complex)
Classification: HYDROLASE/DNA
Source organism: Leptographium truncatum; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.73 Å
Deposited: 2017-10-20
Authors: Brown, C., Zhang, K., McMurrough, T.A., Gloor, G.B., Edgell, D.R., Junop, M.
PDB entry 6bcu: Cryo-EM structure of the activated RHEB-mTORC1 refined to 3.4 angstrom
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.8 Å
Deposited: 2017-10-20
Authors: Pavletich, N.P., Yang, H.
PDB entry 6bcx: mTORC1 structure refined to 3.0 angstroms
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.23 Å
Deposited: 2017-10-20
Authors: Pavletich, N.P., Yang, H.
PDB entry 6bcy: Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at T360
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2017-10-20
Authors: Kast, D.J., Dominguez, R.
PDB entry 6bcz: Crystal structure of human CYP3A4 bound to an inhibitor
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.23 Å
Deposited: 2017-10-20
Authors: Sevrioukova, I.
PDB entry 6bd0: I-OnuI K227Y, D236A bound to cognate substrate (pre-cleavage complex)
Classification: HYDROLASE/DNA
Source organism: Ophiostoma novo-ulmi subsp. americana; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2017-10-20
Authors: Brown, C., Zhang, K., Laforet, M., McMurrough, T.A., Gloor, G.B., Edgell, D.R., Junop, M.
PDB entry 6bd1: Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at S366
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2017-10-20
Authors: Kast, D.J., Dominguez, R.
PDB entry 6bd2: Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and S366
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2017-10-20
Authors: Kast, D.J., Dominguez, R.
PDB entry 6bd3: Saccharomyces cerevisiae acetohydroxyacid synthase
Classification: TRANSFERASE
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.28 Å
Deposited: 2017-10-21
Authors: Guddat, L.W., Lonhienne, T.
PDB entry 6bd4: Crystal structure of human apo-Frizzled4 receptor
Classification: MEMBRANE PROTEIN
Source organism: Clostridium pasteurianum; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2017-10-21
Authors: Yang, S., Wu, Y., Pu, M., Chen, Y., Dong, S., Guo, Y., Han, G.Y., Stevens, R.C., Zhao, S., Xu, F.
PDB entry 6bd5: Crystal structure of human CYP3A4 bound to an inhibitor
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2017-10-21
Authors: Sevrioukova, I.
PDB entry 6bd6: Crystal structure of human CYP3A4 bound to an inhibitor
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2017-10-21
Authors: Sevrioukova, I.
PDB entry 6bd7: Crystal structure of human CYP3A4 bound to an inhibitor
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.42 Å
Deposited: 2017-10-21
Authors: Sevrioukova, I.
PDB entry 6bd8: Crystal structure of human CYP3A4 bound to an inhibitor
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.38 Å
Deposited: 2017-10-21
Authors: Sevrioukova, I.
PDB entry 6bd9: Saccharomyces cerevisiae acetohydroxyacid synthase
Classification: TRANSFERASE
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.982 Å
Deposited: 2017-10-22
Authors: Guddat, L.W., Lonhienne, T.
PDB entry 6bda: Wild-type I-OnuI bound to A3G substrate (post-cleavage complex)
Classification: HYDROLASE/DNA
Source organism: Ophiostoma novo-ulmi subsp. americana; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.88 Å
Deposited: 2017-10-22
Authors: Brown, C., Zhang, K., Laforet, M., McMurrough, T., Gloor, G.B., Edgell, D.R., Junop, M.
PDB entry 6bdb: I-OnuI K227Y, D236A bound to A3G substrate (pre-cleavage complex)
Classification: HYDROLASE
Source organism: Ophiostoma novo-ulmi subsp. americana; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2017-10-22
Authors: Brown, C., Zhang, K., McMurrough, T.A., Laforet, M., Gloor, G.B., Edgell, D.R., Junop, M.
PDB entry 6bdc: Structure of Hcp1 from Flavobacterium johnsoniae
Classification: PROTEIN TRANSPORT
Source organism: Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.496 Å
Deposited: 2017-10-22
Authors: Bohn, A.J., Russell, A.B., Robinson, H., Mougous, J.D., Whitney, J.C.
PDB entry 6bdd: Crystal structure of Fe(II) unliganded H-NOX protein from K. algicida
Classification: SIGNALING PROTEIN
Source organism: Kordia algicida OT-1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.901 Å
Deposited: 2017-10-22
Authors: Bruegger, J.J., Hespen, C.W., Marletta, M.A.
PDB entry 6bde: Crystal structure of Fe(II) unliganded H-NOX protein mutant A71G from K. algicida
Classification: SIGNALING PROTEIN
Source organism: Kordia algicida OT-1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.641 Å
Deposited: 2017-10-22
Authors: Bruegger, J.J., Hespen, C.W., Marletta, M.A.
PDB entry 6bdf: 2.8 A resolution reconstruction of the Thermoplasma acidophilum 20S proteasome using cryo-electron microscopy
Classification: HYDROLASE
Source organism: Thermoplasma acidophilum
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.8 Å
Deposited: 2017-10-23
Authors: Campbell, M.G., Veesler, D., Cheng, A., Potter, C.S., Carragher, B.
PDB entry 6bdg: HFQ monomer in spacegroup p6 at 1.93 angstrom resolution
Classification: CHAPERONE
Source organism: Escherichia coli O45:K1 (strain S88 / ExPEC)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.964 Å
Deposited: 2017-10-23
Authors: Brown, C., Zhang, K., Seo, C., Ellis, M.J., Hanniford, D.B., Junop, M.
PDB entry 6bdh: Crystal structure of human CYP3A4 bound to an inhibitor
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2017-10-23
Authors: Sevrioukova, I.
PDB entry 6bdi: Crystal structure of human CYP3A4 bound to an inhibitor
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.57 Å
Deposited: 2017-10-23
Authors: Sevrioukova, I.
PDB entry 6bdj: Crystal structure of dioxygenase Tetur07g02040
Classification: METAL BINDING PROTEIN
Source organism: Tetranychus urticae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2017-10-23
Authors: Daneshian, L., Schlachter, C.R., Chruszcz, M.
PDB entry 6bdk: Crystal structure of human CYP3A4 bound to an inhibitor
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.67 Å
Deposited: 2017-10-23
Authors: Sevrioukova, I.
PDB entry 6bdl: Crystal structure of cGMP-dependent protein kinase Ialpha (PKG Ialpha) catalytic domain in apo state
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.96 Å
Deposited: 2017-10-23
Authors: Qin, L., Sankaran, B., Kim, C.
PDB entry 6bdm: Crystal structure of human CYP3A4 bound to an inhibitor
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2017-10-23
Authors: Sevrioukova, I.
PDB entry 6bdn: Crystal structure of human TAO3 kinase binding ADP
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2017-10-23
Authors: Aleshin, A.E., Bankton, L.A., Pinkerton, A., Courtneidge, S.A., Liddington, R.C.
PDB entry 6bdo: Structure of bacterial type II NADH dehydrogenase from Caldalkalibacillus thermarum complexed with a quinone inhibitor HQNO at 2.8A resolution
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Caldalkalibacillus thermarum TA2.A1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2017-10-23
Authors: Cook, G.M., Aragao, D., Nakatani, Y.
PDB entry 6bdp: Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0000071 (Compound 9c) Complex
Classification: TRANSFERASE
Source organism: Schistosoma mansoni
Experimental method: X-RAY DIFFRACTION
Resolution: 1.43 Å
Deposited: 2017-10-24
Authors: Taylor, A.B.
PDB entry 6bdq: Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0000074 (Compound 10a) Complex
Classification: TRANSFERASE
Source organism: Schistosoma mansoni
Experimental method: X-RAY DIFFRACTION
Resolution: 1.83 Å
Deposited: 2017-10-24
Authors: Taylor, A.B.
PDB entry 6bdr: Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0000206 (Compound 9f) Complex
Classification: TRANSFERASE
Source organism: Schistosoma mansoni
Experimental method: X-RAY DIFFRACTION
Resolution: 1.66 Å
Deposited: 2017-10-24
Authors: Taylor, A.B.
PDB entry 6bds: Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0000204 (Compound 11f) Complex
Classification: TRANSFERASE
Source organism: Schistosoma mansoni
Experimental method: X-RAY DIFFRACTION
Resolution: 1.53 Å
Deposited: 2017-10-24
Authors: Taylor, A.B.
PDB entry 6bdt: Crystal Structure of Human Calpain-3 Protease Core Mutant-C129S
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2017-10-24
Authors: Ye, Q., Campbell, R.L., Davies, P.L.
PDB entry 6bdu: Crystal structure of PprA from Deinococcus radiodurans
Classification: DNA BINDING PROTEIN
Source organism: Deinococcus radiodurans
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2017-10-24
Authors: Szabla, R., Czerwinski, M., Junop, M.S.
PDB entry 6bdv: Crystal structure of Caspase 3 S150A
Classification: APOPTOSIS
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.938 Å
Deposited: 2017-10-24
Authors: Thomas, M.E., Grinshpon, R., Swartz, P.D., Clark, A.C.
PDB entry 6bdx: 4-hydroxy tetrahydrodipicolinate reductase from Neisseria gonorrhoeae
Classification: OXIDOREDUCTASE
Source organism: Neisseria gonorrhoeae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2017-10-24
Authors: Pote, S.S., Pye, S.E., Sheahan, T.E., Chruszcz, M.
PDB entry 6bdy: Crystal Structure of the MetH Reactivation Domain bound to Sinefungin
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.512 Å
Deposited: 2017-10-24
Authors: Fick, R.J., Vander Lee, L.P., Trievel, R.C.
PDB entry 6bdz: ADAM10 Extracellular Domain Bound by the 11G2 Fab
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1 Å
Deposited: 2017-10-24
Authors: Seegar, T.C.M.
PDB entry 6be0: AvrA delL154 with IP6, CoA
Classification: TRANSFERASE
Source organism: Salmonella typhimurium (strain 4/74)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.438 Å
Deposited: 2017-10-24
Authors: Labriola, J.M., Nagar, B.
PDB entry 6be1: Cryo-EM structure of serotonin receptor
Classification: MEMBRANE PROTEIN
Source organism: Mus musculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.31 Å
Deposited: 2017-10-24
Authors: Basak, S., Chakrapani, S.
PDB entry 6be2: Crystal structure of a polysaccharide-binding human Fab (F598)
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2017-10-24
Authors: Soliman, C., Ramsland, P.A.
PDB entry 6be3: Crystal structure of a polysaccharide-binding human Fab (F598) in complex with N-acetyl-D-glucosamine (GlcNAc)
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2017-10-24
Authors: Soliman, C., Ramsland, P.A.
PDB entry 6be4: Crystal structure of a polysaccharide-binding human Fab (F598) in complex with nona-N-acetyl-D-glucosamine (9NAc)
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2017-10-24
Authors: Soliman, C., Ramsland, P.A.
PDB entry 6be6: ADAM10 Extracellular Domain
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2017-10-24
Authors: Seegar, T.C.M.
PDB entry 6be7: Solution structure of de novo macrocycle Design8.1
Classification: DE NOVO PROTEIN
Experimental method: SOLUTION NMR
Deposited: 2017-10-24
Authors: Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
PDB entry 6be9: Solution structure of de novo macrocycle design7.1
Classification: DE NOVO PROTEIN
Experimental method: SOLUTION NMR
Deposited: 2017-10-24
Authors: Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, B.
PDB entry 6bea: Crystal structure of the autotransporter UpaB from E. coli strain CFT073
Classification: PROTEIN BINDING
Source organism: Escherichia coli O6:H1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.97 Å
Deposited: 2017-10-25
Authors: Paxman, J.J., Heras, B.
PDB entry 6beb: Crystal structure of VACV D13 in complex with Rifamycin SV
Classification: VIRAL PROTEIN
Source organism: Vaccinia virus WR
Experimental method: X-RAY DIFFRACTION
Resolution: 2.55 Å
Deposited: 2017-10-25
Authors: Garriga, D., Accurso, C., Coulibaly, F.
PDB entry 6bec: Crystal structure of VACV D13 in complex with Rifabutin
Classification: VIRAL PROTEIN
Source organism: Vaccinia virus WR
Experimental method: X-RAY DIFFRACTION
Resolution: 2.91 Å
Deposited: 2017-10-25
Authors: Garriga, D., Accurso, C., Coulibaly, F.
PDB entry 6bed: Crystal structure of VACV D13 in complex with Rifampicin
Classification: VIRAL PROTEIN
Source organism: Vaccinia virus WR
Experimental method: X-RAY DIFFRACTION
Resolution: 2.75 Å
Deposited: 2017-10-25
Authors: Garriga, D., Accurso, C., Coulibaly, F.
PDB entry 6bee: Crystal structure of VACV D13 in complex with Rifaximin
Classification: VIRAL PROTEIN
Source organism: Vaccinia virus WR
Experimental method: X-RAY DIFFRACTION
Resolution: 3.11 Å
Deposited: 2017-10-25
Authors: Garriga, D., Accurso, C., Coulibaly, F.
PDB entry 6bef: Crystal structure of VACV D13 in complex with 3-formyl rifamycin SV
Classification: VIRAL PROTEIN
Source organism: Vaccinia virus WR
Experimental method: X-RAY DIFFRACTION
Resolution: 3.21 Å
Deposited: 2017-10-25
Authors: Garriga, D., Accurso, C., Coulibaly, F.
PDB entry 6beg: Crystal structure of VACV D13 F486A mutant
Classification: VIRAL PROTEIN
Source organism: Vaccinia virus WR
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1 Å
Deposited: 2017-10-25
Authors: Garriga, D., Accurso, C., Coulibaly, F.
PDB entry 6beh: Crystal structure of VACV D13 in complex with Rifapentine
Classification: VIRAL PROTEIN
Source organism: Vaccinia virus (strain Western Reserve)
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2017-10-25
Authors: Garriga, D., Accurso, C., Coulibaly, F.
PDB entry 6bei: Crystal structure of VACV D13 in its apo (unbound) form
Classification: VIRAL PROTEIN
Source organism: Vaccinia virus WR
Experimental method: X-RAY DIFFRACTION
Resolution: 2.81 Å
Deposited: 2017-10-25
Authors: Garriga, D., Accurso, C., Coulibaly, F.
PDB entry 6bej: Crystal structure of manganese superoxide dismutase from Xanthomonas citri
Classification: OXIDOREDUCTASE
Source organism: Xanthomonas citri
Experimental method: X-RAY DIFFRACTION
Resolution: 1.894 Å
Deposited: 2017-10-25
Authors: Goto, L.S., Alexandrino, A.V., Pereira, C.M., Mendoca, D.C., Leonardo, D.A., Pereira, H.M., Garratt, R.C., Novo-Mansur, M.T.M.
PDB entry 6bek: Structure of sIHF bound to an 8bp palindromic DNA
Classification: DNA BINDING PROTEIN/DNA
Source organism: Streptomyces coelicolor; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2017-10-25
Authors: Guarne, A., Nanji, T.N., Shen, Y.
PDB entry 6bel: Ternary complex crystal structure of DNA polymerase Beta with R-isomer of beta-gamma-CHF-dCTP
Classification: TRANSFERASE/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.898 Å
Deposited: 2017-10-25
Authors: Batra, V.K., Wilson, S.H.
PDB entry 6bem: Ternary complex crystal structure of DNA polymerase Beta with S-isomer of beta-gamma-CHCL-dCTP
Classification: TRANSFERASE/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.88 Å
Deposited: 2017-10-25
Authors: Batra, V.K., Wilson, S.H.
PDB entry 6ben: Solution structure of de novo macrocycle design8.2
Classification: DE NOVO PROTEIN
Experimental method: SOLUTION NMR
Deposited: 2017-10-25
Authors: Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, B.
PDB entry 6beo: Solution structure of de novo macrocycle design9.1
Classification: DE NOVO PROTEIN
Experimental method: SOLUTION NMR
Deposited: 2017-10-25
Authors: Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
PDB entry 6beq: Solution structure of de novo macrocycle design10.1
Classification: DE NOVO PROTEIN
Experimental method: SOLUTION NMR
Deposited: 2017-10-25
Authors: Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
PDB entry 6ber: Solution structure of de novo macrocycle design10.2
Classification: DE NOVO PROTEIN
Experimental method: SOLUTION NMR
Deposited: 2017-10-25
Authors: Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
PDB entry 6bes: Solution structure of de novo macrocycle design11_ss
Classification: DE NOVO PROTEIN
Experimental method: SOLUTION NMR
Deposited: 2017-10-25
Authors: Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
PDB entry 6bet: Solution structure of de novo macrocycle design12_ss
Classification: DE NOVO PROTEIN
Experimental method: SOLUTION NMR
Deposited: 2017-10-25
Authors: Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
PDB entry 6beu: Solution structure of de novo macrocycle design14_ss
Classification: DE NOVO PROTEIN
Experimental method: SOLUTION NMR
Deposited: 2017-10-25
Authors: Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
PDB entry 6bev: Human Single Domain Sulfurtranferase TSTD1
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.043 Å
Deposited: 2017-10-25
Authors: Motl, N., Akey, D.L., Smith, J.L., Banerjee, R.
PDB entry 6bew: Solution structure of de novo macrocycle design7.2
Classification: DE NOVO PROTEIN
Experimental method: SOLUTION NMR
Deposited: 2017-10-25
Authors: Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
PDB entry 6bf2: Solution structure of a Bcl-xL S62E mutant
Classification: APOPTOSIS
Source organism: Homo sapiens
Experimental method: SOLUTION NMR
Deposited: 2017-10-25
Authors: Viacava Follis, A., Phillips, A., Kriwacki, R.W.
PDB entry 6bf3: Solution structure of de novo macrocycle design7.3a
Classification: DE NOVO PROTEIN
Experimental method: SOLUTION NMR
Deposited: 2017-10-25
Authors: Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
PDB entry 6bf4: Crystal Structure of HIV-1 Clade AE Strain CNE55 gp120 Core in Complex with Neutralizing Antibody VRC-PG05 that Targets the Center of the Silent Face on the Outer Domain of gp120
Classification: viral protein/immune system
Source organism: Homo sapiens; Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.382 Å
Deposited: 2017-10-25
Authors: Zhou, T., Kwong, P.D.
PDB entry 6bf5: Solution structure of de novo macrocycle design7.3a
Classification: DE NOVO PROTEIN
Experimental method: SOLUTION NMR
Deposited: 2017-10-25
Authors: Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
PDB entry 6bf6: Cryo-EM structure of human insulin degrading enzyme
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 6.5 Å
Deposited: 2017-10-26
Authors: Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J.
PDB entry 6bf7: Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain
Classification: HYDROLASE/IMMUNE SYSTEM
Source organism: Homo sapiens; Mus musculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 6.5 Å
Deposited: 2017-10-26
Authors: Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J.
PDB entry 6bf8: Cryo-EM structure of human insulin degrading enzyme in complex with insulin
Classification: BIOSYNTHETIC PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.2 Å
Deposited: 2017-10-26
Authors: Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J.
PDB entry 6bf9: Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain
Classification: HYDROLASE/IMMUNE SYSTEM
Source organism: Homo sapiens; Mus musculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 7.2 Å
Deposited: 2017-10-26
Authors: Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J.
PDB entry 6bfa: Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1553
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Toxoplasma gondii
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2017-10-26
Authors: Merritt, E.A.
PDB entry 6bfb: Crystal structure of a F. nucleatum FMN riboswitch bound to WG-3
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.82 Å
Deposited: 2017-10-26
Authors: Rizvi, N.F., Fischmann, T.O.
PDB entry 6bfc: Cryo-EM structure of human insulin degrading enzyme in complex with insulin
Classification: HYDROLASE/HORMONE
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.7 Å
Deposited: 2017-10-26
Authors: Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J.
PDB entry 6bfd: BACE crystal structure with hydroxy pyrrolidine inhibitor
Classification: HYDROLASE/HYDROLASE Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.62 Å
Deposited: 2017-10-26
Authors: Timm, D.E.
PDB entry 6bfe: BACE crystal structure with hydroxy pyrrolidine inhibitor
Classification: HYDROLASE/HYDROLASE Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.51 Å
Deposited: 2017-10-26
Authors: Timm, D.E.
PDB entry 6bff: Structure of the aminoglycoside acetyltransferase AAC(6')-Im
Classification: TRANSFERASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2017-10-26
Authors: Smith, C.A., Vakulenko, S.B.
PDB entry 6bfg: Crystal structure of monotopic membrane protein (S)-mandelate dehydrogenase
Classification: OXIDOREDUCTASE
Source organism: Pseudomonas putida
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2017-10-26
Authors: Sukumar, N.
PDB entry 6bfh: Structure of the kanamycin complex of aminoglycoside acetyltransferase AAC(6')-Im
Classification: TRANSFERASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2017-10-26
Authors: Smith, C.A., Vakulenko, S.B.
PDB entry 6bfi: Vinculin homolog in a sponge (phylum Porifera) reveals vertebrate-like cell adhesions involved in early multicellular evolution
Classification: CELL ADHESION
Source organism: Oscarella pearsei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2017-10-26
Authors: Weis, W.I., Chodaparambil, J.V.
PDB entry 6bfj: Caspase-3 Mutant - T245D,S249D
Classification: apoptosis/inhibitor
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.543 Å
Deposited: 2017-10-26
Authors: Thomas, M.E., Grinshpon, R., Swartz, P.D., Clark, A.C.
PDB entry 6bfk: Caspase-3 Mutant- T245A
Classification: apoptosis/inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.753 Å
Deposited: 2017-10-26
Authors: Thomas, M.E., Grinshpon, R., Swartz, P.D., Clark, A.C.
PDB entry 6bfl: Caspase-3 Mutant- D9A,D28A,T245D
Classification: apoptosis/inhibitor
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.87 Å
Deposited: 2017-10-26
Authors: Thomas, M.E., Grinshpon, R., Swartz, P.D., Clark, A.C.
PDB entry 6bfn: Crystal structure of human IRAK1
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.26 Å
Deposited: 2017-10-26
Authors: Wang, L., Qiao, Q., Wu, H.
PDB entry 6bfo: Caspase-3 Mutant- T245D
Classification: apoptosis/inhibitor
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.54 Å
Deposited: 2017-10-26
Authors: Thomas, M.E., Grinshpon, R., Swartz, P.D., Clark, A.C.
PDB entry 6bfp: Bovine trypsin bound to potent inhibitor
Classification: HYDROLASE/HYDROLASE inhibitor
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.292 Å
Deposited: 2017-10-26
Authors: Partridge, J.R., Choy, R.M.
PDB entry 6bfq: The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2017-10-26
Authors: Dhagat, U., Hercus, T.R., Broughton, S.E., Nero, T.L., Lopez, A.F., Parker, M.W.
PDB entry 6bfs: The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2017-10-26
Authors: Dhagat, U., Hercus, T.R., Broughton, S.E., Nero, T.L., Lopez, A.F., Parker, M.W.
PDB entry 6bft: Structure of Bevacizumab Fab mutant in complex with VEGF
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.55 Å
Deposited: 2017-10-27
Authors: Christie, M., Christ, D.
PDB entry 6bfu: Glycan shield and fusion activation of a deltacoronavirus spike glycoprotein fine-tuned for enteric infections
Classification: VIRAL PROTEIN
Source organism: Porcine deltacoronavirus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.5 Å
Deposited: 2017-10-27
Authors: Xiong, X., Tortorici, M.A., Snijder, S., Yoshioka, C., Walls, A.C., Li, W., Seattle Structural Genomics Center for Infectious Disease (SSGCID), McGuire, A.T., Rey, F.A., Bosch, B.J., Veesler, D.
PDB entry 6bfv: Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 5-fluoro-1,2-dihydropyrimidin-2-one
Classification: TRANSFERASE
Source organism: Schistosoma mansoni
Experimental method: X-RAY DIFFRACTION
Resolution: 1.921 Å
Deposited: 2017-10-27
Authors: Faheem, M., Neto, J.B., Collins, P., Pearce, N.M., Valadares, N.F., Bird, L., Pereira, H.M., Delft, F.V., Barbosa, J.A.R.G.
PDB entry 6bfw: BACE crystal structure with hydroxy morpholine inhibitor
Classification: HYDROLASE/HYDROLASE Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.84 Å
Deposited: 2017-10-27
Authors: Timm, D.E.
PDB entry 6bfx: BACE crystal structure with hydroxy pyrrolidine inhibitor
Classification: HYDROLASE/HYDROLASE Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.99 Å
Deposited: 2017-10-27
Authors: Timm, D.E.
PDB entry 6bfy: Crystal structure of enolase from Escherichia coli with bound 2-phosphoglycerate substrate
Classification: LYASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.81 Å
Deposited: 2017-10-27
Authors: Erlandsen, H., Wright, D., Krucinska, J.
PDB entry 6bfz: Crystal structure of enolase from E. coli with a mixture of apo form, substrate, and product form
Classification: LYASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.21 Å
Deposited: 2017-10-27
Authors: Erlandsen, H., Wright, D., Krucinska, J.
PDB entry 6bg0: Caspase-3 Mutant - D9A,D28A,S150D
Classification: apoptosis/inhibitor
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.125 Å
Deposited: 2017-10-27
Authors: Thomas, M.E., Grinshpon, R., Swartz, P.D., Clark, A.C.
PDB entry 6bg1: Caspase-3 Mutant - D9A,D28A,S150E
Classification: apoptosis/inhibitor
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.88 Å
Deposited: 2017-10-27
Authors: Thomas, M.E., Grinshpon, R., Swartz, P.D., Clark, A.C.
PDB entry 6bg2: Crystal structure of cGMP-dependent protein kinase Ialpha (PKG Ialpha) catalytic domain in AMP-PNP bound state
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.83 Å
Deposited: 2017-10-27
Authors: Qin, L., Sankaran, B., Kim, C.
PDB entry 6bg3: Structure of (3S,4S)-1-benzyl-4-(3-(3-(trifluoromethyl)phenyl)ureido)piperidin-3-yl acetate bound to DCN1
Classification: HYDROLASE, LIGASE/INHIBITOR
Source organism: Enterobacteria phage T4; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.05 Å
Deposited: 2017-10-27
Authors: Guy, R.K., Schulman, B.A., Scott, D.C., Hammill, J.T.
PDB entry 6bg4: Caspase-3 Mutant- T152D
Classification: apoptosis/inhibitor
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.87 Å
Deposited: 2017-10-27
Authors: Thomas, M.E., Grinshpon, R., Swartz, P.D., Clark, A.C.
PDB entry 6bg5: Structure of 1-(benzo[d][1,3]dioxol-5-ylmethyl)-1-(1-propylpiperidin-4-yl)-3-(3-(trifluoromethyl)phenyl)urea bound to DCN1
Classification: HYDROLASE, LIGASE/INHIBITOR
Source organism: Enterobacteria phage T4; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.1 Å
Deposited: 2017-10-27
Authors: Guy, R.K., Schulman, B.A., Scott, D.C., Hammill, J.T.
PDB entry 6bg6: Crystal structure of S111A mutant of human macrophage migration inhibitory factor
Classification: ISOMERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.52 Å
Deposited: 2017-10-27
Authors: Pantouris, G., Lolis, E.
PDB entry 6bg7: Crystal structure of G107A mutant of human macrophage migration inhibitory factor
Classification: ISOMERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.54 Å
Deposited: 2017-10-27
Authors: Pantouris, G., Lolis, E.
PDB entry 6bg8: Shewanella frigidimarina ice-binding protein_1 DUF3494 Domain
Classification: ANTIFREEZE PROTEIN
Source organism: Shewanella frigidimarina (strain NCIMB 400)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.59713 Å
Deposited: 2017-10-27
Authors: Vance, T.D.R., Davies, P.L.
PDB entry 6bg9: HYBRID NMR/CRYO-EM STRUCTURE OF THE HIV-1 RNA DIMERIZATION SIGNAL
Classification: RNA
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY, SOLUTION NMR
Resolution: 9 Å
Deposited: 2017-10-27
Authors: Summers, M.F.
PDB entry 6bga: 2B4 I-Ek TCR-MHC complex with affinity-enhancing Velcro peptide
Classification: IMMUNE SYSTEM
Source organism: Mus musculus; synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 2.307 Å
Deposited: 2017-10-27
Authors: Gee, M.H., Sibener, L.V., Birnbaum, M.E., Jude, K.M., Garcia, K.C.
PDB entry 6bgb: Crystal Structure of the 16mer GCAGNCUUAAGUCUGC containing BrPh 7-triazolyl-8-aza-7-deazaadenosine
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2017-10-27
Authors: Fisher, A.J., Beal, P.A., Mumbleau, M.M.
PDB entry 6bgc: The crystal structure of the W145A variant of TpMglB-2 (Tp0684) with bound glucose
Classification: SUGAR BINDING PROTEIN
Source organism: Treponema pallidum (strain Nichols)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.082 Å
Deposited: 2017-10-27
Authors: Brautigam, C.A., Norgard, M.V., Deka, R.K.
PDB entry 6bgd: The crystal structure of the W145A variant of TpMglB-2 (Tp0684) with bound ligand
Classification: SUGAR BINDING PROTEIN
Source organism: Treponema pallidum (strain Nichols)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.47 Å
Deposited: 2017-10-27
Authors: Brautigam, C.A., Norgard, M.V., Deka, R.K.
PDB entry 6bge: HELICOBACTER PYLORI ATPASE, HP0525, IN COMPLEX WITH 1G2 COMPOUND
Classification: ATP binding Protein
Source organism: Helicobacter pylori
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2017-10-27
Authors: Arya, T., Casu, B., Baron, C.
PDB entry 6bgf: Crystal structure of cysteine-bound ferrous form of the crosslinked human cysteine dioxygenase
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.251 Å
Deposited: 2017-10-28
Authors: Liu, A., Li, J., Shin, I.
PDB entry 6bgg: Solution NMR structures of the BRD3 ET domain in complex with a CHD4 peptide
Classification: PROTEIN BINDING
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: SOLUTION NMR
Deposited: 2017-10-28
Authors: Wai, D.C.C., Szyszka, T.N., Campbell, A.E., Kwong, C., Wilkinson-White, L., Silva, A.P.G., Low, J.K.K., Kwan, A.H., Gamsjaeger, R., Lu, B., Vakoc, C.R., Blobel, G.A., Mackay, J.P.
PDB entry 6bgh: Solution NMR structure of Brd3 ET domain bound to Brg1 peptide
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: SOLUTION NMR
Deposited: 2017-10-28
Authors: Szyszka, T.N., Wai, D.C., Mackay, J.P.
PDB entry 6bgi: Cryo-EM structure of the TMEM16A calcium-activated chloride channel in nanodisc
Classification: MEMBRANE PROTEIN
Source organism: Mus musculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.8 Å
Deposited: 2017-10-28
Authors: Dang, S., Feng, S., Tien, J., Peters, C.J., Bulkley, D., Lolicato, M., Zhao, J., Zuberbuhler, K., Ye, W., Qi, J., Chen, T., Craik, C.S., Jan, Y.N., Minor Jr., D.L., Cheng, Y., Jan, L.Y.
PDB entry 6bgj: Cryo-EM structure of the TMEM16A calcium-activated chloride channel in LMNG
Classification: MEMBRANE PROTEIN
Source organism: Mus musculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.8 Å
Deposited: 2017-10-28
Authors: Dang, S., Feng, S., Tien, J., Peters, C.J., Bulkley, D., Lolicato, M., Zhao, J., Zuberbuhler, K., Ye, W., Qi, L., Chen, T., Craik, C.S., Jan, Y.N., Minor Jr., D.L., Cheng, Y., Jan, L.Y.
PDB entry 6bgk: Caspase-3 Mutant- D9A,D28A,T152D
Classification: APOPTOSIS
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.87 Å
Deposited: 2017-10-28
Authors: Thomas, M.E., Grinshpon, R., Swartz, P.D., Clark, A.C.
PDB entry 6bgl: Doubly PafE-capped 20S core particle in Mycobacterium tuberculosis
Classification: HYDROLASE
Source organism: Mycobacterium tuberculosis
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.4 Å
Deposited: 2017-10-28
Authors: Li, H., Hu, K.
PDB entry 6bgm: Crystal structure of ferrous form of the crosslinked human cysteine dioxygenase
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.206 Å
Deposited: 2017-10-28
Authors: Liu, A., Li, J., Shin, I.
PDB entry 6bgn: Crystal Structure of 4-Oxalocrotonate Tautomerase After Incubation with 5-Fluoro-2-hydroxy-2,4-pentadienoate
Classification: ISOMERASE
Source organism: Pseudomonas putida
Experimental method: X-RAY DIFFRACTION
Resolution: 1.51 Å
Deposited: 2017-10-29
Authors: Zhang, Y., Li, W., Stack, T.
PDB entry 6bgo: Singly PafE-capped 20S CP in Mycobacterium tuberculosis
Classification: HYDROLASE
Source organism: Mycobacterium tuberculosis
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.2 Å
Deposited: 2017-10-29
Authors: Li, H., Hu, K.
PDB entry 6bgp: Crystal Structure of Human Calpain-3 Protease Core Mutant-C129A
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.75 Å
Deposited: 2017-10-29
Authors: Ye, Q., Campbell, R.L., Davies, P.L.
PDB entry 6bgq: Caspase-3 Mutant - S150D
Classification: apoptosis/inhibitor
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.97 Å
Deposited: 2017-10-29
Authors: Thomas, M.E., Grinshpon, R., Swartz, P.D., Clark, A.C.
PDB entry 6bgr: Caspase-3 Mutant - S150E
Classification: apoptosis/inhibitor
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.16 Å
Deposited: 2017-10-29
Authors: Thomas, M.E., Grinshpon, R., Swartz, P.D., Clark, A.C.
PDB entry 6bgs: Caspase-3 Mutant - S150Y
Classification: apoptosis/inhibitor
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2017-10-29
Authors: Thomas, M.E., Grinshpon, R., Swartz, P.D., Clark, A.C.
PDB entry 6bgt: Structure of Trastuzumab Fab mutant in complex with Her2 extracellular domain
Classification: TRANSFERASE/IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2017-10-29
Authors: Christie, M., Christ, D.
PDB entry 6bgu: LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)(propoxy)methyl)-1H-pyrrolo[3,2-b]pyridine (Compound N9)
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.684 Å
Deposited: 2017-10-29
Authors: Horton, J.R., Cheng, X.
PDB entry 6bgv: LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)(2-(piperidin-1-yl)ethoxy)methyl)-1l2-pyrrolo[3,2-b]pyridine-7-carboxylic acid (Compound N40)
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.592 Å
Deposited: 2017-10-29
Authors: Horton, J.R., Cheng, X.
PDB entry 6bgw: LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)(2-(4,4-difluoropiperidin-1-yl)ethoxy)methyl)-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid(Compound N41)
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.644 Å
Deposited: 2017-10-29
Authors: Horton, J.R., Cheng, X.
PDB entry 6bgx: LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)((4,4-difluorocyclohexyl)methoxy)methyl)-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid(Compound N42)
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.882 Å
Deposited: 2017-10-29
Authors: Horton, J.R., Cheng, X.
PDB entry 6bgy: LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)(2-(1-methylpyrrolidin-2-yl)ethoxy)methyl)-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid(Compound 46)
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.22 Å
Deposited: 2017-10-29
Authors: Horton, J.R., Cheng, X.
PDB entry 6bgz: LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)(2-(1-methyl-1H-imidazol-2-yl)ethoxy)methyl)-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid (Compound N47)
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.688 Å
Deposited: 2017-10-29
Authors: Horton, J.R., Cheng, X.
PDB entry 6bh0: LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR (R)-2-((2-chlorophenyl)(2-(piperidin-1-yl)ethoxy)methyl)-1l2-pyrrolo[3,2-b]pyridine-7-carboxylic acid (Compound N51)
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.985 Å
Deposited: 2017-10-29
Authors: Horton, J.R., Cheng, X.
PDB entry 6bh1: LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR (S)-2-((2-chlorophenyl)(2-(piperidin-1-yl)ethoxy)methyl)-1l2-pyrrolo[3,2-b]pyridine-7-carboxylic acid (Compound N52)
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.932 Å
Deposited: 2017-10-29
Authors: Horton, J.R., Cheng, X.
PDB entry 6bh2: LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR (R)-N-(1-(3-isopropyl-1H-pyrazole-5-carbonyl)pyrrolidin-3-yl)cyclopropanecarboxamide (Compound N54)
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.447 Å
Deposited: 2017-10-29
Authors: Horton, J.R., Cheng, X.
PDB entry 6bh3: LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR (S)-N-(1-(3-isopropyl-1H-pyrazole-5-carbonyl)pyrrolidin-3-yl)cyclopropanecarboxamide (Compound N55)
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.701 Å
Deposited: 2017-10-29
Authors: Horton, J.R., Cheng, X.
PDB entry 6bh4: LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 5-(1-(tert-butyl)-1H-pyrazol-4-yl)-6-isopropyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile (Compound N75/CPI-48)
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.047 Å
Deposited: 2017-10-29
Authors: Horton, J.R., Cheng, X.
PDB entry 6bh5: LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)(3-(piperidin-1-yl)propoxy)methyl)-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid (Compound N48)
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.651 Å
Deposited: 2017-10-29
Authors: Horton, J.R., Cheng, X.
PDB entry 6bh7: Phosphotriesterase variant R18+254S
Classification: HYDROLASE
Source organism: Brevundimonas diminuta
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2017-10-30
Authors: Miton, C.M., Campbell, E.C., Jackson, C.J., Tokuriki, N.
PDB entry 6bh8: Crystal structure of ZMPSTE24 in complex with phosphoramidon
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.85 Å
Deposited: 2017-10-30
Authors: Goblirsch, B.R., Arachea, B.T., Wiener, M.C.
PDB entry 6bh9: Caspase-3 Mutant - T152A
Classification: apoptosis/inhibitor
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.94 Å
Deposited: 2017-10-30
Authors: Thomas, M.E., Grinshpon, R., Swartz, P.D., Clark, A.C.
PDB entry 6bha: Caspase-3 Mutant - T152V
Classification: apoptosis/inhibitor
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.603 Å
Deposited: 2017-10-30
Authors: Thomas, M.E., Grinshpon, R., Swartz, P.D., Clark, A.C.
PDB entry 6bhb: Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 2-aminopyrimidin-5-ol
Classification: TRANSFERASE
Source organism: Schistosoma mansoni
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2017-10-30
Authors: Faheem, M., Neto, J.B., Collins, P., Pearce, N.M., Valadares, N.F., Bird, L., Pereira, H.M., Delft, F.V., Barbosa, J.A.R.G.
PDB entry 6bhc: Crystal structure of pseduokinase PEAK1 (Sugen Kinase 269)
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2017-10-30
Authors: Ha, B.H., Boggon, T.J.
PDB entry 6bhd: Crystal structure of SETDB1 with a modified H3 peptide
Classification: TRANSFERASE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.25 Å
Deposited: 2017-10-30
Authors: Qin, S., Tempel, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
PDB entry 6bhe: Crystal structure of SETDB1 with a modified H3 peptide
Classification: TRANSFERASE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.35 Å
Deposited: 2017-10-30
Authors: Qin, S., Tempel, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
PDB entry 6bhf: Crystal structure of the petidylprolyl cis,trans-isomerase from Helicobacter pylori
Classification: ISOMERASE
Source organism: Helicobacter pylori (strain ATCC 700392 / 26695)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.09 Å
Deposited: 2017-10-30
Authors: Yaseen, A., Audette, G.F.
PDB entry 6bhg: Crystal structure of SETDB1 with a modified H3 peptide
Classification: TRANSFERASE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2017-10-30
Authors: Qin, S., Tempel, W., Dong, A., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
PDB entry 6bhh: Crystal structure of SETDB1 with a modified H3 peptide
Classification: TRANSFERASE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2017-10-30
Authors: Qin, S., Tempel, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
PDB entry 6bhi: Crystal structure of SETDB1 with a modified H3 peptide
Classification: TRANSFERASE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2017-10-30
Authors: Qin, S., Tempel, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
PDB entry 6bhj: Structure of HIV-1 Reverse Transcriptase Bound to a 38-mer Hairpin Template-Primer RNA-DNA Aptamer
Classification: TRANSFERASE/DNA
Source organism: Human immunodeficiency virus 1; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.81 Å
Deposited: 2017-10-30
Authors: Ruiz, F.X., Miller, M.T., Tuske, S., Das, K., Arnold, E.
PDB entry 6bhk: Phosphotriesterase variant R18deltaL7
Classification: HYDROLASE
Source organism: Brevundimonas diminuta
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2017-10-30
Authors: Miton, C.M., Campbell, E.C., Jackson, C.J., Tokuriki, N.
PDB entry 6bhl: Phosphotriesterase variant S5deltaL7
Classification: HYDROLASE
Source organism: Brevundimonas diminuta
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2017-10-30
Authors: Miton, C.M., Campbell, E.C., Jackson, C.J., Tokuriki, N.
PDB entry 6bhn: Red Light-Absorbing State of NpR6012g4, a Red/Green Cyanobacteriochrome
Classification: SIGNALING PROTEIN
Source organism: Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
Experimental method: SOLUTION NMR
Deposited: 2017-10-31
Authors: Yu, Q., Lim, S., Rockwell, N.C., Martin, S.S., Lagarias, J.C., Ames, J.B.
PDB entry 6bho: Green Light-Absorbing State of NpR6012g4, a Red/Green Cyanobacteriochrome
Classification: SIGNALING PROTEIN
Source organism: Nostoc punctiforme PCC 73102
Experimental method: SOLUTION NMR
Deposited: 2017-10-31
Authors: Lim, S., Yu, Q., Rockwell, N.C., Martin, S.S., Lagarias, J.C., Ames, J.B.
PDB entry 6bhp: Crystal structure of the Chlamydomonas reinhardtii LCI1 channel
Classification: MEMBRANE PROTEIN
Source organism: Chlamydomonas reinhardtii
Experimental method: X-RAY DIFFRACTION
Resolution: 3.209 Å
Deposited: 2017-10-31
Authors: Chou, T.-H., Radhakrishnan, A.
PDB entry 6bhq: Mouse Immunoglobulin G 2c Fc fragment with complex-type glycan
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2017-10-31
Authors: Falconer, D., Barb, A.
PDB entry 6bhr: HIV-1 immature CTD-SP1 hexamer in complex with IP6
Classification: VIRAL PROTEIN
Source organism: Human immunodeficiency virus type 1 group M subtype B (isolate BH10)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.908 Å
Deposited: 2017-10-31
Authors: Zadrozny, K., Wagner, J.M., Ganser-Pornillos, B.K., Pornillos, O.