LiteFold/PDB huggingface dataset:
PDB entry 7laz: Crystal structure of the first bromodomain (BD1) of human BRD3 bound to ERK5-IN-1
Classification: GENE REGULATION/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.302 Å
Deposited: 2021-01-07
Authors: Karim, M.R., Bikowitz, M.J., Schonbrunn, E.
PDB entry 7lb0: Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-295
Classification: GENE REGULATION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.33 Å
Deposited: 2021-01-07
Authors: Karim, M.R., Schonbrunn, E.
PDB entry 7lb1: Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-585
Classification: GENE REGULATION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.35 Å
Deposited: 2021-01-07
Authors: Karim, M.R., Schonbrunn, E.
PDB entry 7lb2: Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-589
Classification: GENE REGULATION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2021-01-07
Authors: Karim, M.R., Schonbrunn, E.
PDB entry 7lb3: Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ZS1-580
Classification: GENE REGULATION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2021-01-07
Authors: Karim, M.R., Schonbrunn, E.
PDB entry 7lb4: Crystal structure of the second bromodomain (BD2) of human BRD3 bound to bromosporine
Classification: GENE REGULATION/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.004 Å
Deposited: 2021-01-07
Authors: Karim, M.R., Bikowitz, M.J., Schonbrunn, E.
PDB entry 7lb5: Pyridoxal 5'-phosphate synthase-like subunit PDX1.2 (Arabidopsis thaliana)
Classification: PLANT PROTEIN
Source organism: Arabidopsis thaliana
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.16 Å
Deposited: 2021-01-07
Authors: Novikova, I.V., Evans, J.E.
PDB entry 7lb6: PDX1.2/PDX1.3 co-expression complex
Classification: PLANT PROTEIN
Source organism: Arabidopsis thaliana
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.16 Å
Deposited: 2021-01-07
Authors: Novikova, I.V., Evans, J.E.
PDB entry 7lb7: Joint X-ray/neutron structure of SARS-CoV-2 main protease (3CL Mpro) in complex with Telaprevir
Classification: HYDROLASE/HYDROLASE inhibitor
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION, NEUTRON DIFFRACTION
Deposited: 2021-01-07
Authors: Kovalevsky, A.Y., Kneller, D.W., Coates, L.
PDB entry 7lb8: Structure of a ferrichrome importer FhuCDB from E. coli
Classification: TRANSPORT PROTEIN
Source organism: Escherichia coli (strain K12)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.4 Å
Deposited: 2021-01-07
Authors: Hu, W., Zheng, H.
PDB entry 7lb9: Pseudomonas fluorescens G150T isocyanide hydratase (G150T-3) at 274K, Refmac5-refined
Classification: LYASE
Source organism: Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.101 Å
Deposited: 2021-01-07
Authors: Su, Z., Dasgupta, M., Poitevin, F., Mathews, I.I., van den Bedem, H., Wall, M.E., Yoon, C.H., Wilson, M.A.
PDB entry 7lba: E. coli Agmatinase
Classification: HYDROLASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2021-01-07
Authors: Chitrakar, I., Ahmed, S.F., Torelli, A.T., French, J.B.
PDB entry 7lbc: Structure of human GGT1 in complex with Lnt2-65 compound
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.28 Å
Deposited: 2021-01-07
Authors: Terzyan, S.S., Hanigan, M.
PDB entry 7lbd: Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59K mutant with pyruvate bound in the active site in C2221 space group
Classification: LYASE
Source organism: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.99 Å
Deposited: 2021-01-07
Authors: Saran, S., Yazdi, M.M., Sanders, D.A.R.
PDB entry 7lbe: CryoEM structure of the HCMV Trimer gHgLgO in complex with neutralizing fabs 13H11 and MSL-109
Classification: VIRAL PROTEIN/Immune System
Source organism: Homo sapiens; Human cytomegalovirus; Human cytomegalovirus (strain Merlin)
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.9 Å
Deposited: 2021-01-07
Authors: Kschonsak, M., Rouge, L., Arthur, C.P., Hoangdung, H., Patel, N., Kim, I., Johnson, M., Kraft, E., Rohou, A.L., Gill, A., Martinez-Martin, N., Payandeh, J., Ciferri, C.
PDB entry 7lbf: CryoEM structure of the HCMV Trimer gHgLgO in complex with human Platelet-derived growth factor receptor alpha and neutralizing fabs 13H11 and MSL-109
Classification: VIRAL PROTEIN/Immune System
Source organism: Homo sapiens; Human cytomegalovirus; Human cytomegalovirus (strain Merlin)
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.8 Å
Deposited: 2021-01-07
Authors: Kschonsak, M., Rouge, L., Arthur, C.P., Hoangdung, H., Patel, N., Kim, I., Johnson, M., Kraft, E., Rohou, A.L., Gill, A., Martinez-Martin, N., Payandeh, J., Ciferri, C.
PDB entry 7lbg: CryoEM structure of the HCMV Trimer gHgLgO in complex with human Transforming growth factor beta receptor type 3 and neutralizing fabs 13H11 and MSL-109
Classification: VIRAL PROTEIN/Immune System
Source organism: Homo sapiens; Human cytomegalovirus; Human cytomegalovirus (strain Merlin)
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.6 Å
Deposited: 2021-01-07
Authors: Kschonsak, M., Rouge, L., Arthur, C.P., Hoangdung, H., Patel, N., Kim, I., Johnson, M., Kraft, E., Rohou, A.L., Gill, A., Martinez-Martin, N., Payandeh, J., Ciferri, C.
PDB entry 7lbh: Wild-type Pseudomonas fluorescens isocyanide hydratase (WT-1) at 274K, PHENIX-refined
Classification: LYASE
Source organism: Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.15 Å
Deposited: 2021-01-08
Authors: Su, Z., Dasgupta, M., Poitevin, F., Mathews, I.I., van den Bedem, H., Wall, M.E., Yoon, C.H., Wilson, M.A.
PDB entry 7lbi: Wild-type Pseudomonas fluorescens isocyanide hydratase (WT-2) at 274K, PHENIX-refined
Classification: LYASE
Source organism: Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.2 Å
Deposited: 2021-01-08
Authors: Su, Z., Dasgupta, M., Poitevin, F., Mathews, I.I., van den Bedem, H., Wall, M.E., Yoon, C.H., Wilson, M.A.
PDB entry 7lbj: Crystal structure of octaprenyl diphosphate synthase from Stenotrophomonas maltophilia
Classification: TRANSFERASE
Source organism: Stenotrophomonas maltophilia (strain K279a)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2021-01-08
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 7lbk: Crystal structure of human Survivin bound to histone H3 T3phK4me3 peptide
Classification: CELL CYCLE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2021-01-08
Authors: Niedzialkowska, E., Minor, W., Stukenberg, P.T.
PDB entry 7lbl: Structure of Human IgG1 Fc
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.13 Å
Deposited: 2021-01-08
Authors: Fields, J.K., Sundberg, E.J.
PDB entry 7lbm: Structure of the human Mediator-bound transcription pre-initiation complex
Classification: TRANSCRIPTION/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.8 Å
Deposited: 2021-01-08
Authors: Abdella, R., Talyzina, A., He, Y.
PDB entry 7lbn: X-ray crystal structure of the SARS-CoV-2 main protease with Calpain I Inhibitor
Classification: VIRAL PROTEIN
Source organism: Severe acute respiratory syndrome coronavirus 2; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.76 Å
Deposited: 2021-01-08
Authors: Narwal, M., Murakami, K.S.
PDB entry 7lbo: Crystal structure of human Survivin bound to histone H3 T3phK4me1 peptide
Classification: CELL CYCLE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2021-01-08
Authors: Niedzialkowska, E., Minor, W., Stukenberg, P.T.
PDB entry 7lbp: Crystal structure of human Survivin bound to histone H3T3phK4ac peptide
Classification: CELL CYCLE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2021-01-08
Authors: Niedzialkowska, E., Minor, W., Stukenberg, P.T.
PDB entry 7lbq: Crystal structure of human Survivin bound to histone H3 T3phK4me2 peptide
Classification: CELL CYCLE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.69 Å
Deposited: 2021-01-08
Authors: Niedzialkowska, E., Minor, W., Stukenberg, P.T.
PDB entry 7lbr: SARS-CoV-2 papain-like protease (PLpro) bound to inhibitor XR8-89
Classification: VIRAL PROTEIN/INHIBITOR
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2021-01-08
Authors: Ratia, K.M., Xiong, R., Thatcher, G.R.
PDB entry 7lbs: SARS-CoV-2 papain-like protease (PLpro) bound to inhibitor XR8-24
Classification: VIRAL PROTEIN/INHIBITOR
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2021-01-08
Authors: Ratia, K.M., Xiong, R., Thatcher, G.R.
PDB entry 7lbt: Crystal structure of the second bromodomain (BD2) of human BRD3 bound to ERK5-IN-1
Classification: GENE REGULATION/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2021-01-08
Authors: Karim, M.R., Bikowitz, M.J., Schonbrunn, E.
PDB entry 7lbu: Crystal structure of the Propionibacterium acnes surface sialidase
Classification: HYDROLASE
Source organism: Cutibacterium acnes
Experimental method: X-RAY DIFFRACTION
Resolution: 2.11 Å
Deposited: 2021-01-08
Authors: Yu, A.C.Y., Volkers, G., Strynadka, N.C.J.
PDB entry 7lbv: Crystal structure of the Propionibacterium acnes surface sialidase in complex with Neu5Ac2en
Classification: HYDROLASE
Source organism: Cutibacterium acnes
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2021-01-09
Authors: Yu, A.C.Y., Volkers, G., Strynadka, N.C.J.
PDB entry 7lbw: Crystal structure of TFAM (mitochondrial transcription factor A) bridging two non-sequence specific DNA substrates
Classification: TRANSCRIPTION/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.84 Å
Deposited: 2021-01-09
Authors: Choi, W.S., Garcia-Diaz, M.
PDB entry 7lbx: Crystal structure of TFAM (mitochondrial transcription factor A) in complex with LSP
Classification: TRANSCRIPTION/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2021-01-09
Authors: Choi, W.S., Garcia-Diaz, M.
PDB entry 7lby: Bacterial cellulose synthase BcsB with polyalanine BcsA model
Classification: TRANSFERASE
Source organism: Escherichia coli (strain K12)
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.2 Å
Deposited: 2021-01-09
Authors: Acheson, J.F., Zimmer, J.
PDB entry 7lbz: Zoogloea ramigera biosynthetic thiolase Y218E mutant
Classification: TRANSFERASE
Source organism: Zoogloea ramigera
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2021-01-09
Authors: Marshall, A.C., Bruning, J.B.
PDB entry 7lc0: Structure of D-Glucosaminate-6-phosphate Ammonia-lyase
Classification: LYASE
Source organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2021-01-09
Authors: Phillips, R.S.
PDB entry 7lc1: Crystal Structure of KRAS4b (GMPPNP-bound) in complex with the RBD-PH domains of SIN1
Classification: ONCOPROTEIN, Hydrolase
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2021-01-09
Authors: Dharmaiah, S., Simanshu, D.K.
PDB entry 7lc2: Crystal Structure of KRAS4b-Q61R (GMPPNP-bound) in complex with the RAS-binding domain (RBD) of SIN1
Classification: ONCOPROTEIN, Hydrolase
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2021-01-09
Authors: Dharmaiah, S., Simanshu, D.K.
PDB entry 7lc3: CryoEM Structure of KdpFABC in E1-ATP state
Classification: MEMBRANE PROTEIN
Source organism: Escherichia coli (strain K12)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.23 Å
Deposited: 2021-01-09
Authors: Sweet, M.E., Larsen, C., Pedersen, B.P., Stokes, D.L.
PDB entry 7lc4: Crystal structure of Pseudomonas aeruginosa PBP3 in complex with gamma-lactam YU253911
Classification: HYDROLASE/HYDROLASE Inhibitor
Source organism: Pseudomonas aeruginosa
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2021-01-09
Authors: van den Akker, F., Kumar, V.
PDB entry 7lc5: Crystal structure of epoxyqueuosine reductase QueH from Thermotoga maritima
Classification: OXIDOREDUCTASE
Source organism: Thermotoga maritima MSB8
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2021-01-09
Authors: Li, Q., Bruner, S.D.
PDB entry 7lc6: Cryo-EM Structure of KdpFABC in E2-P state with BeF3
Classification: MEMBRANE PROTEIN
Source organism: Escherichia coli (strain K12)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.7 Å
Deposited: 2021-01-09
Authors: Sweet, M.E., Larsen, C., Pedersen, B.P., Stokes, D.L.
PDB entry 7lc7: Crystal structure of epoxyqueuosine reductase QueH in complex with GMP from Thermotoga maritima
Classification: OXIDOREDUCTASE
Source organism: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.58 Å
Deposited: 2021-01-09
Authors: Li, Q., Bruner, S.D.
PDB entry 7lc8: SARS-CoV-2 spike Protein TM domain
Classification: VIRAL PROTEIN
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: SOLUTION NMR
Deposited: 2021-01-10
Authors: Fu, Q., Chou, J.J.
PDB entry 7lc9: Cryo-EM structure of the N-terminal alpha-synuclein truncation 41-140
Classification: PROTEIN FIBRIL
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.2 Å
Deposited: 2021-01-10
Authors: Xiaodan, N., Ryan, P.M., Jiansen, J., Jennifer, C.L.
PDB entry 7lca: Zoogloea ramigera biosynthetic thiolase Y218E/delH221 mutant
Classification: TRANSFERASE
Source organism: Zoogloea ramigera
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2021-01-10
Authors: Marshall, A.C., Bruning, J.B.
PDB entry 7lcb: C1B domain of Protein kinase C in complex with prostratin and phosphatidylcholine
Classification: LIPID BINDING PROTEIN
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2021-01-10
Authors: Katti, S.S., Krieger, I.V.
PDB entry 7lcc: Helitron transposase bound to LTS
Classification: RECOMBINATION
Source organism: synthetic construct; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.66 Å
Deposited: 2021-01-10
Authors: Kosek, D., Dyda, F.
PDB entry 7lcd: Crystal structure of human polymerase eta complexed with syn N7-acetophenoneguanine
Classification: DNA BINDING PROTEIN/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2021-01-10
Authors: Jung, H., Lee, S.
PDB entry 7lce: Structure of D-Glucosaminate-6-phosphate Ammonia-lyase
Classification: LYASE
Source organism: Salmonella typhimurium
Experimental method: X-RAY DIFFRACTION
Resolution: 2.58 Å
Deposited: 2021-01-10
Authors: Phillips, R.S.
PDB entry 7lcf: Dihydrodipicolinate synthase (DHDPS) from C.jejuni, with pyruvate bound in the active site and L-lysine bound at the allosteric site in C121 space group
Classification: LYASE
Source organism: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.69 Å
Deposited: 2021-01-10
Authors: Saran, S., Sanders, D.A.R.
PDB entry 7lcg: The mature Usutu SAAR-1776, Model A
Classification: VIRUS
Source organism: Usutu virus
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.42 Å
Deposited: 2021-01-11
Authors: Khare, B., Klose, T., Fang, Q., Kuhn, R.
PDB entry 7lch: The mature Usutu SAAR-1776, Model B
Classification: VIRUS
Source organism: Usutu virus
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.35 Å
Deposited: 2021-01-11
Authors: Khare, B., Klose, T., Fang, Q., Kuhn, R.
PDB entry 7lci: PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R):Gs complex
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.9 Å
Deposited: 2021-01-11
Authors: Belousoff, M.J., Johnson, R.M., Drulyte, I., Yu, L., Kotecha, A., Danev, R., Wootten, D., Zhang, X., Sexton, P.M.
PDB entry 7lcj: PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R):Gs complex
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.82 Å
Deposited: 2021-01-11
Authors: Belousoff, M.J., Johnson, R.M., Drulyte, I., Yu, L., Kotecha, A., Danev, R., Wootten, D., Zhang, X., Sexton, P.M.
PDB entry 7lck: PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R)
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.24 Å
Deposited: 2021-01-11
Authors: Belousoff, M.J., Johnson, R.M., Drulyte, I., Yu, L., Kotecha, A., Danev, R., Wootten, D., Zhang, X., Sexton, P.M.
PDB entry 7lcl: Zoogloea ramigera biosynthetic thiolase Q183Y mutant
Classification: TRANSFERASE
Source organism: Zoogloea ramigera
Experimental method: X-RAY DIFFRACTION
Resolution: 2.295 Å
Deposited: 2021-01-11
Authors: Marshall, A.C., Bruning, J.B.
PDB entry 7lcm: Receiver Domain of RssB bound to beryllofluoride
Classification: SIGNALING PROTEIN
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.91 Å
Deposited: 2021-01-11
Authors: Deaconescu, A.M., Schwartz, J., Son, J.
PDB entry 7lcn: Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1050.1
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.35 Å
Deposited: 2021-01-11
Authors: Manne, K., Acharya, P.
PDB entry 7lco: Improved Feline Drugs as SARS-CoV-2 Mpro Inhibitors: Structure-Activity Studies & Micellar Solubilization for Enhanced Bioavailability
Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2021-01-11
Authors: Khan, M.B., Lu, J., Arutyunova, E., Young, H.S., Lemieux, M.J.
PDB entry 7lcp: N-terminal finger stabilizes feline drug GC376 in coronavirus 3CL protease
Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR
Source organism: Severe acute respiratory syndrome coronavirus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2021-01-11
Authors: Khan, M.B., Arutyunova, E., Young, H.S., Lemieux, M.J.
PDB entry 7lcq: N-terminal finger stabilizes feline drug GC376 in coronavirus 3CL protease
Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR
Source organism: Severe acute respiratory syndrome coronavirus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2021-01-11
Authors: Khan, M.B., Arutyunova, E., Young, H.S., Lemieux, M.J.
PDB entry 7lcr: Improved Feline Drugs as SARS-CoV-2 Mpro Inhibitors: Structure-Activity Studies & Micellar Solubilization for Enhanced Bioavailability
Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2021-01-11
Authors: Khan, M.B., Arutyunova, E., Young, H.S., Lemieux, M.J.
PDB entry 7lcs: Improved Feline Drugs as SARS-CoV-2 Mpro Inhibitors: Structure-Activity Studies & Micellar Solubilization for Enhanced Bioavailability
Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2021-01-11
Authors: Khan, M.B., Arutyunova, E., Young, H.S., Lemieux, M.J.
PDB entry 7lct: Improved Feline Drugs as SARS-CoV-2 Mpro Inhibitors: Structure-Activity Studies & Micellar Solubilization for Enhanced Bioavailability
Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 1.93 Å
Deposited: 2021-01-11
Authors: Khan, M.B., Arutyunova, E., Young, H.S., Lemieux, M.J.
PDB entry 7lcu: X-ray structure of Furin bound to BOS-318, a small molecule inhibitor
Classification: HYDROLASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.24 Å
Deposited: 2021-01-11
Authors: Campobasso, N., Reid, R.
PDB entry 7lcv: Factor H enhancing human antibody fragment (Fab) to meningococcal Factor H binding protein
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Neisseria meningitidis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2021-01-11
Authors: Beernink, P.T., Sands, N.
PDB entry 7lcw: Aspartimidylated Lasso Peptide Lihuanodin
Classification: UNKNOWN FUNCTION
Source organism: Lihuaxuella thermophila
Experimental method: SOLUTION NMR
Deposited: 2021-01-11
Authors: Link, A.J., Cao, L.
PDB entry 7lcx: Wild-type Pseudomonas fluorescens isocyanide hydratase (WT-3) at 274K, Phenix-refined
Classification: LYASE
Source organism: Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.2 Å
Deposited: 2021-01-12
Authors: Su, Z., Dasgupta, M., Yoon, C.H., Wilson, M.A.
PDB entry 7lcy: Crystal structure of the ligand-free ARM domain from Drosophila SARM1
Classification: HYDROLASE
Source organism: Drosophila melanogaster
Experimental method: X-RAY DIFFRACTION
Resolution: 3.35 Å
Deposited: 2021-01-12
Authors: Gu, W., Nanson, J.D., Luo, Z., McGuinness, H.Y., Manik, M.K., Jia, X., Ve, T., Kobe, B.
PDB entry 7lcz: Crystal structure of the ARM domain from Drosophila SARM1 in complex with NMN
Classification: HYDROLASE
Source organism: Drosophila melanogaster
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2021-01-12
Authors: Gu, W., Nanson, J.D., Luo, Z., Jia, X., Manik, M.K., Ve, T., Kobe, B.
PDB entry 7ld0: Cryo-EM structure of ligand-free Human SARM1
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.1 Å
Deposited: 2021-01-12
Authors: Nanson, J.D., Gu, W., Luo, Z., Jia, X., Landsberg, M.J., Kobe, B., Ve, T.
PDB entry 7ld1: Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1047
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.4 Å
Deposited: 2021-01-12
Authors: Manne, K., Acharya, P.
PDB entry 7ld2: Zoogloea ramigera biosynthetic thiolase Q183Y mutant, RbCl soak
Classification: TRANSFERASE
Source organism: Zoogloea ramigera
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2021-01-12
Authors: Marshall, A.C., Bruning, J.B.
PDB entry 7ld3: Cryo-EM structure of the human adenosine A1 receptor-Gi2-protein complex bound to its endogenous agonist and an allosteric ligand
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.2 Å
Deposited: 2021-01-12
Authors: Draper-Joyce, C.J., Danev, R., Thal, D.M., Christopoulos, A., Glukhova, A.
PDB entry 7ld4: Cryo-EM structure of the human adenosine A1 receptor-Gi2-protein complex bound to its endogenous agonist
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.3 Å
Deposited: 2021-01-12
Authors: Draper-Joyce, C.J., Danev, R., Thal, D.M., Christopoulos, A., Glukhova, A.
PDB entry 7ld5: polynucleotide phosphorylase
Classification: TRANSFERASE/RNA
Source organism: Mycolicibacterium smegmatis; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.07 Å
Deposited: 2021-01-12
Authors: Goldgur, Y., Shuman, S., De La Cruz, M.J., Ghosh, S., Unciuleac, M.-C.
PDB entry 7ld6: G150A Pseudomonas fluorescens isocyanide hydratase (G150A-1) at 274K, Phenix-refined
Classification: LYASE
Source organism: Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.3 Å
Deposited: 2021-01-12
Authors: Su, Z., Dasgupta, M., Yoon, C.H., Wilson, M.A.
PDB entry 7ld7: G150A Pseudomonas fluorescens isocyanide hydratase (G150A-2) at 274K, Phenix-refined
Classification: LYASE
Source organism: Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.25 Å
Deposited: 2021-01-12
Authors: Su, Z., Dasgupta, M., Yoon, C.H., Wilson, M.A.
PDB entry 7ld8: Crystal Structure of Putative non-heme bromoperoxidase BpoC from Mycobacterium tuberculosis H37Rv
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2021-01-12
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 7ld9: Structure of human GGT1 in complex with ABBA
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.42 Å
Deposited: 2021-01-12
Authors: Terzyan, S.S., Hanigan, M.
PDB entry 7lda: Crystal structure of a ribose-5-phosphate isomerase from Stenotrophomonas maltophilia K279a
Classification: ISOMERASE
Source organism: Stenotrophomonas maltophilia (strain K279a)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2021-01-13
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 7ldb: G150A Pseudomonas fluorescens isocyanide hydratase (G150A-3) at 274K, Phenix-refined
Classification: LYASE
Source organism: Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.35 Å
Deposited: 2021-01-13
Authors: Su, Z., Dasgupta, M., Yoon, C.H., Wilson, M.A.
PDB entry 7ldc: Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E mutant
Classification: TRANSFERASE
Source organism: Zoogloea ramigera
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2021-01-13
Authors: Marshall, A.C., Bruning, J.B.
PDB entry 7ldd: native AMPA receptor
Classification: MEMBRANE PROTEIN/IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.4 Å
Deposited: 2021-01-13
Authors: Yu, J., Rao, P., Gouaux, E.
PDB entry 7lde: native AMPA receptor
Classification: MEMBRANE PROTEIN
Source organism: Mus musculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.9 Å
Deposited: 2021-01-13
Authors: Yu, J., Rao, P., Gouaux, E.
PDB entry 7ldf: High resolution NMR solution structure of a de novo designed minimal thioredoxin fold protein
Classification: DE NOVO PROTEIN
Source organism: synthetic construct
Experimental method: SOLUTION NMR
Deposited: 2021-01-13
Authors: Urbauer, J.L., Strauch, E.M.
PDB entry 7ldg: Crystal structure of the MEILB2-BRCA2 complex
Classification: RECOMBINATION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.56 Å
Deposited: 2021-01-13
Authors: Nandakumar, J., Pendlebury, D.F.
PDB entry 7ldi: G150T Pseudomonas fluorescens isocyanide hydratase (G150T-2) at 274K, Phenix-refined
Classification: LYASE
Source organism: Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.2 Å
Deposited: 2021-01-13
Authors: Su, Z., Dasgupta, M., Yoon, C.H., Wilson, M.A.
PDB entry 7ldj: SARS-CoV-2 receptor binding domain in complex with WNb-2
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Severe acute respiratory syndrome coronavirus 2; Vicugna pacos
Experimental method: X-RAY DIFFRACTION
Resolution: 2.36 Å
Deposited: 2021-01-13
Authors: Pymm, P., Dietrich, M.H., Tan, L.L., Adair, A., Tham, W.H.
PDB entry 7ldk: Structure of human respiratory syncytial virus nonstructural protein 2 (NS2)
Classification: VIRAL PROTEIN
Source organism: Human respiratory syncytial virus A
Experimental method: X-RAY DIFFRACTION
Resolution: 2.82 Å
Deposited: 2021-01-13
Authors: Chatterjee, S., Borek, D., Otwinowski, Z., Amarasinghe, G.K., Leung, D.W.
PDB entry 7ldl: Improved Feline Drugs as SARS-CoV-2 Mpro Inhibitors: Structure-Activity Studies & Micellar Solubilization for Enhanced Bioavailability
Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2021-01-13
Authors: Khan, M.B., Lu, J., Arutyunova, E., Young, H.S., Lemieux, M.J.
PDB entry 7ldm: G150T Pseudomonas fluorescens isocyanide hydratase (G150T-1) at 274K, Phenix-refined
Classification: LYASE
Source organism: Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.15 Å
Deposited: 2021-01-13
Authors: Su, Z., Dasgupta, M., Yoon, C.H., Wilson, M.A.
PDB entry 7ldo: G150T Pseudomonas fluorescens isocyanide hydratase (G150T-3) at 274K, Phenix-refined
Classification: LYASE
Source organism: Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.1 Å
Deposited: 2021-01-13
Authors: Su, Z., Dasgupta, M., Yoon, C.H., Wilson, M.A.
PDB entry 7ldq: Crystal structure of putative NAD(P)H-flavin oxidoreductase from Haemophilus influenzae R2846
Classification: OXIDOREDUCTASE
Source organism: Haemophilus influenzae R2846
Experimental method: X-RAY DIFFRACTION
Resolution: 1.15 Å
Deposited: 2021-01-13
Authors: Maltseva, N., Kim, Y., Endres, M., Crofts, T., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 7ldt: Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E mutant, RbCl soak
Classification: TRANSFERASE
Source organism: Zoogloea ramigera
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2021-01-14
Authors: Marshall, A.C., Bruning, J.B.
PDB entry 7ldu: Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E/delH221 mutant
Classification: TRANSFERASE
Source organism: Zoogloea ramigera
Experimental method: X-RAY DIFFRACTION
Resolution: 2.85 Å
Deposited: 2021-01-14
Authors: Marshall, A.C., Bruning, J.B.
PDB entry 7ldv: Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E/delH221/S227K mutant
Classification: TRANSFERASE
Source organism: Zoogloea ramigera
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2021-01-14
Authors: Marshall, A.C., Bruning, J.B.
PDB entry 7ldw: Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E/delH221/S227K/G248T mutant
Classification: TRANSFERASE
Source organism: Zoogloea ramigera
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2021-01-14
Authors: Marshall, A.C., Bruning, J.B.
PDB entry 7ldx: SARS-CoV-2 Main protease immature form - F2X Entry Library E06 fragment
Classification: HYDROLASE
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 2.23 Å
Deposited: 2021-01-14
Authors: Noske, G.D., Nakamura, A.M., Gawriljuk, V.O., Lima, G.M.A., Zeri, A.C.M., Nascimento, A.F.Z., Oliva, G., Godoy, A.S.
PDB entry 7ldy: HIV-1 Protease WT (NL4-3) in Complex with TMC-126
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.984 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7ldz: HIV-1 Protease WT (NL4-3) in Complex with GRL-98065
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.861 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7le0: HIV-1 Protease WT (NL4-3) in Complex with a Darunavir Derivative
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.952 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7le1: HIV-1 Protease WT (NL4-3) in Complex with UMass2
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.001 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7le2: HIV-1 Protease WT (NL4-3) in Complex with UMass4
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.971 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7le3: HIV-1 Protease WT (NL4-3) in Complex with UMass5
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.87 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7le4: HIV-1 Protease WT (NL4-3) in Complex with UMass7
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.993 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7le5: HIV-1 Protease WT (NL4-3) in Complex with UMass9
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.863 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7le6: HIV-1 Protease WT (NL4-3) in Complex with UMass10
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.962 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7le7: HIV-1 Protease WT (NL4-3) in Complex with GS-8374
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.978 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7le8: HIV-1 Protease WT (NL4-3) in Complex with PD4 (LR4-23)
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.644 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7le9: HIV-1 Protease WT (NL4-3) in Complex with PD5 (LR4-22)
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.797 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7lea: HIV-1 Protease WT (NL4-3) in Complex with PU1 (LR3-46)
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7leb: HIV-1 Protease WT (NL4-3) in Complex with PU2 (LR2-79)
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.89 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7lec: HIV-1 Protease WT (NL4-3) in Complex with PU3 (LR3-69)
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.94 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7led: HIV-1 Protease WT (NL4-3) in Complex with PU4 (LR2-78)
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.996 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7lee: HIV-1 Protease WT (NL4-3) in Complex with PU5 (LR4-47)
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.795 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7lef: HIV-1 Protease WT (NL4-3) in Complex with PU7 (LR3-67)
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.93 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7leg: HIV-1 Protease WT (NL4-3) in Complex with PU8 (LR4-06)
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.96 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7leh: HIV-1 Protease WT (NL4-3) in Complex with PU9 (LR2-80)
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7lei: HIV-1 Protease WT (NL4-3) in Complex with PU10 (LR4-07)
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.943 Å
Deposited: 2021-01-14
Authors: Lockbaum, G.J., Rusere, L.N., Henes, M., Kosovrasti, K., Lee, S.K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
PDB entry 7lej: Crystal structure of the second bromodomain (BD2) of human BRDT bound to Volasertib
Classification: GENE REGULATION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.73 Å
Deposited: 2021-01-14
Authors: Chan, A., Karim, M.R., Schonbrunn, E.
PDB entry 7lek: Crystal structure of the second bromodomain (BD2) of human BRDT bound to ERK5-IN-1
Classification: GENE REGULATION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.75 Å
Deposited: 2021-01-14
Authors: Chan, A., Karim, M.R., Schonbrunn, E.
PDB entry 7lel: Crystal structure of the second bromodomain (BD2) of human BRDT bound to Bromosporine
Classification: GENE REGULATION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2021-01-14
Authors: Chan, A., Karim, M.R., Schonbrunn, E.
PDB entry 7lem: Crystal structure of the first bromodomain (BD1) of human BRDT bound to LRRK2-IN-1
Classification: GENE REGULATION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.89 Å
Deposited: 2021-01-14
Authors: Chan, A., Karim, M.R., Schonbrunn, E.
PDB entry 7len: Crystal structure of the epidermal growth factor receptor extracellular region with R84K mutation in complex with epiregulin crystallized with trehalose
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2021-01-14
Authors: Hu, C., Leche II, C.A., Stayrook, S.E., Ferguson, K.M., Lemmon, M.A.
PDB entry 7leo: C1B domain of Protein kinase C in complex with diacylglycerol-lactone (AJH-836) and 1,2-diheptanoyl-sn-glycero-3-phosphocholine
Classification: LIPID BINDING PROTEIN
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2021-01-14
Authors: Katti, S.S., Krieger, I.
PDB entry 7lep: The composite LBD-TMD structure combined from all hippocampal AMPAR subtypes at 3.25 Angstrom resolution
Classification: MEMBRANE PROTEIN
Source organism: Mus musculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.25 Å
Deposited: 2021-01-14
Authors: Yu, J., Rao, P., Gouaux, E.
PDB entry 7leq: Structure of importin a2 bound to p50 NLS
Classification: PROTEIN TRANSPORT
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.24 Å
Deposited: 2021-01-14
Authors: Florio, T.J., Lokareddy, R.K., Cingolani, G.
PDB entry 7ler: Netrin-1 filament assembly
Classification: SIGNALING PROTEIN
Source organism: Gallus gallus
Experimental method: X-RAY DIFFRACTION
Resolution: 5.99 Å
Deposited: 2021-01-14
Authors: McDougall, M., Gupta, M., Stetefeld, J.
PDB entry 7les: Acanthamoeba castellanii CYP51 (AcCYP51)-Imidazole complex
Classification: OXIDOREDUCTASE
Source organism: Acanthamoeba castellanii str. Neff
Experimental method: X-RAY DIFFRACTION
Resolution: 2.65 Å
Deposited: 2021-01-15
Authors: Sharma, V., Podust, L.M.
PDB entry 7let: Structure of importin a2 bound to the p50- and p65-NLSs
Classification: PROTEIN TRANSPORT
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2021-01-15
Authors: Florio, T.J., Lokareddy, R.K., Cingolani, G.
PDB entry 7leu: Structure of importin a2 bound to p65-NLS
Classification: PROTEIN TRANSPORT
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.82 Å
Deposited: 2021-01-15
Authors: Florio, T.J., Lokareddy, R.K., Cingolani, G.
PDB entry 7lev: The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with ammonium ion at the metal coordination site at 1.70 Angstrom resolution
Classification: LYASE
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2021-01-15
Authors: Hilario, E., Dunn, M.F., Mueller, L.J.
PDB entry 7lew: Crystal structure of UBE2G2 in complex with the UBE2G2-binding region of AUP1
Classification: LIGASE/Transferase
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.736 Å
Deposited: 2021-01-15
Authors: Liang, Y.-H., Smith, C.E., Tsai, Y.C., Weissman, A.M., Ji, X.
PDB entry 7lex: Trimeric human Arginase 1 in complex with mAb1 - 2 hArg:3 mAb1 complex
Classification: HYDROLASE/IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.6 Å
Deposited: 2021-01-15
Authors: Gomez-Llorente, Y., Scapin, G., Palte, R.L.
PDB entry 7ley: Trimeric human Arginase 1 in complex with mAb5
Classification: HYDROLASE/IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.05 Å
Deposited: 2021-01-15
Authors: Gomez-Llorente, Y., Scapin, G., Palte, R.L.
PDB entry 7lez: Trimeric human Arginase 1 in complex with mAb1 - 2 hArg:2 mAb1 complex
Classification: HYDROLASE/IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.15 Å
Deposited: 2021-01-15
Authors: Gomez-Llorente, Y., Scapin, G., Palte, R.L.
PDB entry 7lf0: Trimeric human Arginase 1 in complex with mAb2
Classification: HYDROLASE/IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.68 Å
Deposited: 2021-01-15
Authors: Gomez-Llorente, Y., Scapin, G., Palte, R.L.
PDB entry 7lf1: Trimeric human Arginase 1 in complex with mAb3
Classification: HYDROLASE/IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.04 Å
Deposited: 2021-01-15
Authors: Gomez-Llorente, Y., Scapin, G., Palte, R.L.
PDB entry 7lf2: Trimeric human Arginase 1 in complex with mAb4
Classification: HYDROLASE/IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.72 Å
Deposited: 2021-01-15
Authors: Gomez-Llorente, Y., Scapin, G., Palte, R.L.
PDB entry 7lf3: C1B domain of Protein kinase C in complex with diacylglycerol-lactone AJH-836
Classification: LIPID BINDING PROTEIN
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.13 Å
Deposited: 2021-01-15
Authors: Katti, S.S., Krieger, I.V.
PDB entry 7lf4: Structure of importin a3 bound to the p50- and p65-NLSs
Classification: PROTEIN TRANSPORT
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.85 Å
Deposited: 2021-01-15
Authors: Florio, T.J., Lokareddy, R.K., Cingolani, G.
PDB entry 7lf5: Structure of Hyperglycosylated Human IgG1 Fc (Fc267)
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2021-01-15
Authors: Fields, J.K., Sundberg, E.J.
PDB entry 7lf6: Structure of lysosomal membrane protein
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.5 Å
Deposited: 2021-01-15
Authors: Shen, C., Fu, T.M., Wang, L.F., Rawson, S., Wu, H.
PDB entry 7lf7: Fab 6D12 bound to ApoL1 NTD
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.026 Å
Deposited: 2021-01-15
Authors: Ultsch, M., Kirchhofer, D.
PDB entry 7lf8: Fab 6D12 bound to ApoL2 NTD
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2021-01-15
Authors: Ultsch, M., Kirchhofer, D.
PDB entry 7lf9: Structure of Hyperglycosylated Human IgG1 Fc (Fc329)
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2021-01-15
Authors: Fields, J.K., Sundberg, E.J.
PDB entry 7lfa: Fab 3B6 bound to ApoL1 NTD
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.857 Å
Deposited: 2021-01-15
Authors: Ultsch, M., Kirchhofer, D.
PDB entry 7lfb: Fab 7D6 bound to ApoL1 NTD
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.913 Å
Deposited: 2021-01-16
Authors: Ultsch, M., Kirchhofer, D.
PDB entry 7lfc: Structure of importin a3 bound to p50 NLS
Classification: PROTEIN TRANSPORT
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2021-01-16
Authors: Florio, T.J., Lokareddy, R.K., Cingolani, G.