LiteFold/PDB huggingface dataset:
PDB entry 3nw2: Novel nanomolar Imidazopyridines as selective Nitric Oxide Synthase (iNOS) inhibitors: SAR and structural insights
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2010-07-09
Authors: Graedler, U., Fuchss, T., Ulrich, W.R., Boer, R., Strub, A., Hesslinger, C., Anezo, C., Diederichs, K., Zaliani, A.
PDB entry 3nw3: Crystal structure of the complex of peptidoglycan recognition protein (PGRP-S) with the PGN Fragment at 2.5 A resolution
Classification: IMMUNE SYSTEM
Source organism: Camelus dromedarius
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2010-07-09
Authors: Sharma, P., Dube, D., Sinha, M., Kaur, P., Sharma, S., Singh, T.P.
PDB entry 3nw4: Crystal Structure of Salicylate 1,2-dioxygenase G106A mutant from Pseudoaminobacter salicylatoxidans in complex with gentisate
Classification: OXIDOREDUCTASE
Source organism: Pseudaminobacter salicylatoxidans
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2010-07-09
Authors: Ferraroni, M., Briganti, F., Matera, I.
PDB entry 3nw5: Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with a carbon-linked proline isostere inhibitor (11B)
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.14 Å
Deposited: 2010-07-09
Authors: Sack, J.S.
PDB entry 3nw6: Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with a carbon-linked proline isostere inhibitor (11A)
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2010-07-09
Authors: Sack, J.S.
PDB entry 3nw7: Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with a carbon-linked proline isostere inhibitor (34)
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.11 Å
Deposited: 2010-07-09
Authors: Sack, J.S.
PDB entry 3nw8: Glycoprotein B from Herpes simplex virus type 1, Y179S mutant, high-pH
Classification: VIRAL PROTEIN
Source organism: Human herpesvirus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.75915 Å
Deposited: 2010-07-09
Authors: Stampfer, S.D., Lou, H., Cohen, G.H., Eisenberg, R.J., Heldwein, E.E.
PDB entry 3nw9: Rat COMT in complex with a methylpurin-containing bisubstrate inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2010-07-09
Authors: Ehler, A., Schlatter, D., Stihle, M., Benz, J., Rudolph, M.G.
PDB entry 3nwa: Glycoprotein B from Herpes simplex virus type 1, W174R mutant, low-pH
Classification: VIRAL PROTEIN
Source organism: Human herpesvirus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2629 Å
Deposited: 2010-07-09
Authors: Stampfer, S.D., Lou, H., Cohen, G.H., Eisenberg, R.J., Heldwein, E.E.
PDB entry 3nwb: Rat COMT in complex with a fluorinated desoxyribose-containing bisubstrate inhibitor avoids hydroxyl group
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.3 Å
Deposited: 2010-07-09
Authors: Ehler, A., Schlatter, D., Stihle, M., Benz, J., Rudolph, M.G.
PDB entry 3nwc: Crystal Structure of the Pyrococcus furiosus SMC Protein Hinge Domain
Classification: CELL CYCLE
Source organism: Pyrococcus furiosus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6961 Å
Deposited: 2010-07-09
Authors: Griese, J.J., Hopfner, K.P.
PDB entry 3nwd: Glycoprotein B from Herpes simplex virus type 1, Y179S mutant, low-pH
Classification: VIRAL PROTEIN
Source organism: Human herpesvirus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8803 Å
Deposited: 2010-07-09
Authors: Stampfer, S.D., Lou, H., Cohen, G.H., Eisenberg, R.J., Heldwein, E.E.
PDB entry 3nwe: Rat COMT in complex with a methylated desoxyribose bisubstrate-containing inhibitor avoids hydroxyl group
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2010-07-09
Authors: Ehler, A., Schlatter, D., Stihle, M., Benz, J., Rudolph, M.G.
PDB entry 3nwf: Glycoprotein B from Herpes simplex virus type 1, low-pH
Classification: VIRAL PROTEIN
Source organism: Human herpesvirus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2010-07-09
Authors: Stampfer, S.D., Lou, H., Cohen, G.H., Eisenberg, R.J., Heldwein, E.E.
PDB entry 3nwg: The crystal structure of a microcomparments protein from Desulfitobacterium hafniense DCB
Classification: STRUCTURAL PROTEIN
Source organism: Desulfitobacterium hafniense
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2010-07-09
Authors: Fan, Y., Volkart, L., Gu, M., Axen, S., Greenleaf, W.B., Kerfeld, C., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 3nwh: Crystal structure of BST2/Tetherin
Classification: ANTIVIRAL PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2010-07-09
Authors: Schubert, H.L., Zhai, Q., Hill, C.P.
PDB entry 3nwi: The Soluble Domain Structure of the ZntB Zn2+ Efflux System
Classification: TRANSPORT PROTEIN
Source organism: Salmonella enterica
Experimental method: X-RAY DIFFRACTION
Resolution: 3.13 Å
Deposited: 2010-07-09
Authors: Wan, Q., Dealwis, C.
PDB entry 3nwj: Crystal structure of shikimate kinase from Arabidopsis thaliana (AtSK2)
Classification: TRANSFERASE
Source organism: Arabidopsis thaliana
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2010-07-09
Authors: Fucile, G., Garcia, C., Petit, P., Christendat, D.
PDB entry 3nwk: A second C2221 form of concanavalin A (Canavalia ensiformis)
Classification: SUGAR BINDING PROTEIN
Source organism: Canavalia ensiformis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.09 Å
Deposited: 2010-07-09
Authors: Foroughi, L.M., Kang, Y.N., Matzger, A.J.
PDB entry 3nwl: The crystal structure of the P212121 form of bovine liver catalase previously characterized by electron microscopy
Classification: OXIDOREDUCTASE
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.69 Å
Deposited: 2010-07-09
Authors: Foroughi, L.M., Kang, Y.N., Matzger, A.J.
PDB entry 3nwm: Crystal structure of a single chain construct composed of MHC class I H-2Kd, beta-2microglobulin and a peptide which is an autoantigen for type 1 diabetes
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2010-07-09
Authors: Ramagopal, U.A., Samanta, D., Nathenson, S.G., Almo, S.C.
PDB entry 3nwn: Crystal structure of the human KIF9 motor domain in complex with ADP
Classification: CONTRACTILE PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2010-07-09
Authors: Zhu, H., Tempel, W., He, H., Shen, Y., Wang, J., Brothers, G., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
PDB entry 3nwo: Crystal structure of Proline iminopeptidase Mycobacterium smegmatis
Classification: HYDROLASE
Source organism: Mycobacterium smegmatis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2010-07-09
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 3nwp: Crystal structure of a 6-phosphogluconolactonase (Sbal_2240) from Shewanella baltica OS155 at 1.40 A resolution
Classification: HYDROLASE
Source organism: Shewanella baltica
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2010-07-09
Authors: Joint Center for Structural Genomics (JCSG)
PDB entry 3nwq: X-ray structure of ester chemical analogue [O-Ile50,O-Ile50']HIV-1 protease complexed with MVT-101
Classification: hydrolase/hydrolase inhibitor
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2010-07-10
Authors: Torbeev, V.Y., Kent, S.B.H.
PDB entry 3nwr: Crystal structure of a rubisco-like protein from Burkholderia fungorum
Classification: LYASE
Source organism: Burkholderia fungorum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.498 Å
Deposited: 2010-07-10
Authors: Fedorov, A.A., Fedorov, E.V., Imker, H.J., Gerlt, J.A., Almo, S.C.
PDB entry 3nws: Crystal structure of the N-terminal domain of the yeast telomere-binding and telomerase regulatory protein Cdc13
Classification: CELL CYCLE
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2010-07-10
Authors: Mitchell, M.T., Smith, J.S., Mason, M., Harper, S., Speicher, D.W., Johnson, F.B., Skordalakes, E.
PDB entry 3nwt: Crystal structure of the N-terminal domain of the yeast telomere-binding and telomerase regulatory protein Cdc13
Classification: CELL CYCLE
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2010-07-10
Authors: Mitchell, M.T., Smith, J.S., Mason, M., Harper, S., Speicher, D.W., Johnson, F.B., Skordalakes, E.
PDB entry 3nwu: Substrate induced remodeling of the active site regulates HtrA1 activity
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2 Å
Deposited: 2010-07-11
Authors: Truebestein, L., Tennstaedt, A., Hauske, P., Krojer, T., Kaiser, M., Clausen, T., Ehrmann, M.
PDB entry 3nwv: Human cytochrome c G41S
Classification: APOPTOSIS
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2010-07-11
Authors: Fagerlund, R.D., Wilbanks, S.M.
PDB entry 3nww: P38 Alpha kinase complexed with a 2-aminothiazol-5-yl-pyrimidine based inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.09 Å
Deposited: 2010-07-12
Authors: Sack, J.S.
PDB entry 3nwx: X-ray structure of ester chemical analogue [O-Ile50,O-Ile50']HIV-1 protease complexed with KVS-1 inhibitor
Classification: hydrolase/hydrolase inhibitor
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2010-07-12
Authors: Torbeev, V.Y., Kent, S.B.H.
PDB entry 3nwy: Structure and allosteric regulation of the uridine monophosphate kinase from Mycobacterium tuberculosis
Classification: TRANSFERASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.54 Å
Deposited: 2010-07-12
Authors: Labesse, G., Munier-Lehmann, H.
PDB entry 3nwz: Crystal Structure of BH2602 protein from Bacillus halodurans with CoA, Northeast Structural Genomics Consortium Target BhR199
Classification: Structural Genomics, Unknown function
Source organism: Bacillus halodurans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.566 Å
Deposited: 2010-07-12
Authors: Kuzin, A., Su, M., Seetharaman, J., Sahdev, S., Xiao, R., Ciccosanti, C., Lee, D., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
PDB entry 3nx0: Hinge-loop mutation can be used to control 3D domain swapping and amyloidogenesis of human cystatin C
Classification: HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.04 Å
Deposited: 2010-07-12
Authors: Orlikowska, M., Jankowska, E., Kolodziejczyk, R., Jaskolski, M., Szymanska, A.
PDB entry 3nx1: Crystal structure of Enterobacter sp. Px6-4 Ferulic Acid Decarboxylase
Classification: LYASE
Source organism: Enterobacter sp. Px6-4
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2010-07-12
Authors: Gu, W., Yang, J.K., Lou, Z.Y., Meng, Z.H., Zhang, K.-Q.
PDB entry 3nx2: Enterobacter sp. Px6-4 Ferulic Acid Decarboxylase in complex with substrate analogues
Classification: LYASE
Source organism: Enterobacter sp. Px6-4
Experimental method: X-RAY DIFFRACTION
Resolution: 2.01 Å
Deposited: 2010-07-12
Authors: Gu, W., Yang, J.K., Lou, Z.Y., Meng, Z.H., Zhang, K.-Q.
PDB entry 3nx3: Crystal structure of acetylornithine aminotransferase (argD) from Campylobacter jejuni
Classification: TRANSFERASE
Source organism: Campylobacter jejuni subsp. jejuni
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2010-07-12
Authors: Anderson, S.M., Wawrzak, Z., Onopriyenko, O., Skarina, T., Anderson, W.F., Savchenko, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 3nx4: Crystal structure of the yhdH oxidoreductase from Salmonella enterica in complex with NADP
Classification: OXIDOREDUCTASE
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2010-07-12
Authors: Anderson, S.M., Wawrzak, Z., Peterson, S., Onopriyenko, O., Skarina, T., Anderson, W.F., Savchenko, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 3nx5: The crystal structure of Sanguinarine bound to DNA d(CGTACG)
Classification: DNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.31 Å
Deposited: 2010-07-13
Authors: Ferraroni, M., Bazzicalupi, C., Gratteri, P., Bilia, A.R.
PDB entry 3nx6: Crystal Structure of co-chaperonin, GroES (Xoo4289) from Xanthomonas oryzae pv. oryzae KACC10331
Classification: CHAPERONE
Source organism: Xanthomonas oryzae pv. oryzae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.97 Å
Deposited: 2010-07-13
Authors: Natarajan, S., Doan, T.T.N., Kang, L.-W.
PDB entry 3nx7: Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-Hydroxy-2-(N-(2-hydroxyethyl)4-methoxyphenylsulfonamido)acetamide
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2010-07-13
Authors: Bertini, I., Calderone, V., Fragai, M., Giachetti, A., Loconte, M., Luchinat, C., Maletta, M., Nativi, C., Yeo, K.J.
PDB entry 3nx8: human cAMP dependent protein kinase in complex with phenol
Classification: TRANSFERASE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2010-07-13
Authors: Koester, H., Heine, A., Klebe, G.
PDB entry 3nx9: Crystal structure of type I ribosome inactivating protein in complex with maltose at 1.7A resolution
Classification: HYDROLASE
Source organism: Momordica balsamina
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2010-07-13
Authors: Pandey, N., Kushwaha, G.S., Sinha, M., Kaur, P., Sharma, S., Singh, T.P.
PDB entry 3nxa: X-ray structure of the apo form of human S100A16
Classification: METAL BINDING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2010-07-13
Authors: Calderone, V.
PDB entry 3nxb: Crystal Structure of the Bromodomain of human CECR2
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.83 Å
Deposited: 2010-07-13
Authors: Filippakopoulos, P., Picaud, S., Keates, T., Muniz, J., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
PDB entry 3nxc: Molecular mechanism by which the Escherichia coli nucleoid occlusion factor, SlmA, keeps cytokinesis in check
Classification: DNA BINDING PROTEIN
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2010-07-13
Authors: Tonthat, N.K., Schumacher, M.A.
PDB entry 3nxd: JC polyomavirus VP1 in complex with LSTc
Classification: VIRAL PROTEIN
Source organism: JC polyomavirus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2010-07-13
Authors: Neu, U., Stroeh, L.J., Stehle, T.
PDB entry 3nxe: X-ray structure of ester chemical analogue 'covalent dimer' [Ile50,O-Ile50']HIV-1 protease complexed with MVT-101 inhibitor
Classification: hydrolase/hydrolase inhibitor
Experimental method: X-RAY DIFFRACTION
Resolution: 1.61 Å
Deposited: 2010-07-13
Authors: Torbeev, V.Y., Kent, S.B.H.
PDB entry 3nxf: Robust computational design, optimization, and structural characterization of retroaldol enzymes
Classification: LYASE
Source organism: artificial gene
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2010-07-13
Authors: Althoff, E.A., Jiang, L., Wang, L., Lassila, J.K., Moody, J., Bolduc, J., Wang, Z.Z., Smith, M., Hari, S., Herschlag, D., Stoddard, B.L., Baker, D.
PDB entry 3nxg: JC polyomavirus VP1
Classification: VIRAL PROTEIN
Source organism: JC polyomavirus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2010-07-13
Authors: Neu, U., Stroeh, L.J., Stehle, T.
PDB entry 3nxh: Crystal Structure of the transcriptional regulator yvhJ from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR735.
Classification: transcription regulator
Source organism: Bacillus subtilis subsp. subtilis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.584 Å
Deposited: 2010-07-13
Authors: Vorobiev, S., Chen, Y., Seetharaman, J., Sahdev, S., Xiao, R., Ciccosanti, C., Lee, D., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
PDB entry 3nxj: Crystal Structure of Ketosteroid Isomerase D99N from Pseudomonas Testosteroni (tKSI)
Classification: ISOMERASE
Source organism: Comamonas testosteroni
Experimental method: X-RAY DIFFRACTION
Resolution: 1.966 Å
Deposited: 2010-07-13
Authors: Gonzalez, A., Tsai, Y., Schwans, J., Sunden, F., Herschlag, D.
PDB entry 3nxk: Crystal Structure of Probable Cytoplasmic L-asparaginase from Campylobacter jejuni
Classification: HYDROLASE
Source organism: Campylobacter jejuni subsp. jejuni
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2010-07-14
Authors: Kim, Y., Makowska-Grzyska, M., Maltseva, N., Papazisi, L., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 3nxl: Crystal structure of Glucarate dehydratase from Burkholderia cepacia complexed with magnesium
Classification: LYASE
Source organism: Burkholderia sp. 383
Experimental method: X-RAY DIFFRACTION
Resolution: 1.885 Å
Deposited: 2010-07-14
Authors: Fedorov, A.A., Fedorov, E.V., Gerlt, J.A., Burley, S.K., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC)
PDB entry 3nxn: X-ray structure of ester chemical analogue 'covalent dimer' [Ile50,O-Ile50']HIV-1 protease complexed with KVS-1 inhibitor
Classification: hydrolase/hydrolase inhibitor
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2010-07-14
Authors: Torbeev, V.Y., Kent, S.B.H.
PDB entry 3nxo: Perferential Selection of Isomer Binding from Chiral Mixtures: Alternate Binding Modes Observed for the E- and Z-isomers of a Series of 5-Substituted 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.35 Å
Deposited: 2010-07-14
Authors: Cody, V.
PDB entry 3nxp: Crystal structure of human prethrombin-1
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2010-07-14
Authors: Chen, Z., Bush-Pelc, L.A., Di Cera, E.
PDB entry 3nxq: Angiotensin Converting Enzyme N domain glycsoylation mutant (Ndom389) in complex with RXP407
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.99 Å
Deposited: 2010-07-14
Authors: Anthony, C.S., Corradi, H.R., Schwager, S.L.U., Redelinghuys, P., Georgiadis, D., Dive, V., Acharya, K.R., Sturrock, E.D.
PDB entry 3nxr: Perferential Selection of Isomer Binding from Chiral Mixtures: Alternate Binding Modes Observed for the E- and Z-isomers of a Series of 5-Substituted 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.35 Å
Deposited: 2010-07-14
Authors: Cody, V.
PDB entry 3nxs: Crystal structure of LAO/AO transport system from Mycobacterium smegmatis bound to GDP
Classification: TRANSPORT PROTEIN
Source organism: Mycobacterium smegmatis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2010-07-14
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 3nxt: Preferential Selection of Isomer Binding from Chiral Mixtures: Alternate Binding Modes Observed for the E-and Z-isomers of a Series of 5-substituted 2,4-diaminofuro[2m,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2010-07-14
Authors: Cody, V.
PDB entry 3nxu: Crystal structure of human cytochrome P4503A4 bound to an inhibitor ritonavir
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2010-07-14
Authors: Sevrioukova, I.F., Poulos, T.L.
PDB entry 3nxv: Preferential Selection of Isomer Binding from Chiral Mixtures: Alternate Binding Modes Observed for the E- and Z-isomers of a Series of 5-Substituted 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2010-07-14
Authors: Cody, V.
PDB entry 3nxw: Crystal structure of Staphylococcal nuclease variant Delta+PHS L125A at cryogenic temperature
Classification: HYDROLASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2010-07-14
Authors: Caro, J.A., Schlessman, J.L., Garcia-Moreno, E.B., Heroux, A.
PDB entry 3nxx: Preferential Selection of Isomer Binding from Chiral Mixtures: Alternate Binding Modes Observed for the E- and Z-isomers of a Series of 5-Substituted 2,4-Diaminofuro-2,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.35 Å
Deposited: 2010-07-14
Authors: Cody, V.
PDB entry 3nxy: Preferential Selection of Isomer Binding from Chiral Mixtures: Alernate Binding Modes Observed fro the E- and Z-isomers of a Series of 5-Substituted 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2010-07-14
Authors: Cody, V.
PDB entry 3nxz: Crystal Structure of UreE from Helicobacter pylori (Cu2+ bound form)
Classification: METAL BINDING PROTEIN
Source organism: Helicobacter pylori
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2010-07-14
Authors: Shi, R., Munger, C., Assinas, A., Matte, A., Cygler, M., Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
PDB entry 3ny0: Crystal Structure of UreE from Helicobacter pylori (Ni2+ bound form)
Classification: METAL BINDING PROTEIN
Source organism: Helicobacter pylori
Experimental method: X-RAY DIFFRACTION
Resolution: 3.09 Å
Deposited: 2010-07-14
Authors: Shi, R., Munger, C., Assinas, A., Matte, A., Cygler, M., Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
PDB entry 3ny1: Structure of the ubr-box of the UBR1 ubiquitin ligase
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.085 Å
Deposited: 2010-07-14
Authors: Matta-Camacho, E., Kozlov, G., Li, F., Gehring, K.
PDB entry 3ny2: Structure of the ubr-box of UBR2 ubiquitin ligase
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.61 Å
Deposited: 2010-07-14
Authors: Matta-Camacho, E., Kozlov, G., Li, F., Gehring, K.
PDB entry 3ny3: Structure of the ubr-box of UBR2 in complex with N-degron
Classification: LIGASE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2010-07-14
Authors: Matta-Camacho, E., Kozlov, G., Li, F., Gehring, K.
PDB entry 3ny4: Crystal Structure of BlaC-K73A bound with Cefamandole
Classification: HYDROLASE/ANTIBIOTIC
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.22 Å
Deposited: 2010-07-14
Authors: Tremblay, L.W., Blanchard, J.S.
PDB entry 3ny5: Crystal structure of the RBD domain of serine/threonine-protein kinase B-raf from Homo sapiens. Northeast Structural Genomics Consortium Target HR4694F
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.993 Å
Deposited: 2010-07-14
Authors: Vorobiev, S., Su, M., Seetharaman, J., Patel, P., Xiao, R., Ciccosanti, C., Shastry, R., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
PDB entry 3ny6: Catalytic fragment of cholix toxin from vibrio cholerae in complex with inhibitor V30
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Vibrio cholerae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.68 Å
Deposited: 2010-07-14
Authors: Merrill, A.R., Jorgensen, R.
PDB entry 3ny7: STAS domain of YchM bound to ACP
Classification: MEMBRANE PROTEIN
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.922 Å
Deposited: 2010-07-14
Authors: Moraes, T.F., Reithmeier, R., Strynadka, N.C.S.
PDB entry 3ny8: Crystal structure of the human beta2 adrenergic receptor in complex with the inverse agonist ICI 118,551
Classification: MEMBRANE PROTEIN
Source organism: Enterobacteria phage T4; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.84 Å
Deposited: 2010-07-14
Authors: Wacker, D., Fenalti, G., Brown, M.A., Katritch, V., Abagyan, R., Cherezov, V., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
PDB entry 3ny9: Crystal structure of the human beta2 adrenergic receptor in complex with a novel inverse agonist
Classification: MEMBRANE PROTEIN
Source organism: Enterobacteria phage T4; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.84 Å
Deposited: 2010-07-14
Authors: Fenalti, G., Wacker, D., Brown, M.A., Katritch, V., Abagyan, R., Cherezov, V., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
PDB entry 3nya: Crystal structure of the human beta2 adrenergic receptor in complex with the neutral antagonist alprenolol
Classification: MEMBRANE PROTEIN
Source organism: Enterobacteria phage T4; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.16 Å
Deposited: 2010-07-14
Authors: Brown, M.A., Wacker, D., Fenalti, G., Katritch, V., Abagyan, R., Cherezov, V., Stevens, R.C., GPCR Network (GPCR)
PDB entry 3nyb: Structure and function of the polymerase core of TRAMP, a RNA surveillance complex
Classification: TRANSFERASE/RNA BINDING PROTEIN
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7007 Å
Deposited: 2010-07-14
Authors: Reinisch, K.M., Hamill, S.
PDB entry 3nyc: Crystal Structure of Pseudomonas aeruginosa D-Arginine Dehydrogenase
Classification: OXIDOREDUCTASE
Source organism: Pseudomonas aeruginosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.06 Å
Deposited: 2010-07-14
Authors: Fu, G., Weber, I.T.
PDB entry 3nyd: Crystal Structure of Kemp Eliminase HG-2 Complexed with Transition State Analog 5-Nitro Benzotriazole
Classification: HYDROLASE
Source organism: Thermoascus aurantiacus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.23 Å
Deposited: 2010-07-14
Authors: Lee, T.M., Privett, H.K., Kaiser, J.T., Mayo, S.L.
PDB entry 3nye: Crystal Structure of Pseudomonas aeruginosa D-Arginine Dehydrogenase in Complex with Imino-Arginine
Classification: OXIDOREDUCTASE
Source organism: Pseudomonas aeruginosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.3 Å
Deposited: 2010-07-14
Authors: Fu, G., Weber, I.T.
PDB entry 3nyf: Crystal Structure of Pseudomonas aeruginosa D-Arginine Dehydrogenase in Complex with Imino-Histidine
Classification: OXIDOREDUCTASE
Source organism: Pseudomonas aeruginosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.3 Å
Deposited: 2010-07-15
Authors: Fu, G., Weber, I.T.
PDB entry 3nyg: X-ray structure of ester chemical analogue [O-Gly51,O-Gly51']HIV-1 protease complexed with MVT-101 inhibitor
Classification: hydrolase/hydrolase inhibitor
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2010-07-15
Authors: Torbeev, V.Y., Kent, S.B.H.
PDB entry 3nyi: The crystal structure of a fat acid (stearic acid)-binding protein from Eubacterium ventriosum ATCC 27560.
Classification: LIPID BINDING PROTEIN
Source organism: Eubacterium ventriosum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2010-07-15
Authors: Zhang, R., Tan, K., Li, H., Keigher, L., Babnigg, G., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 3nyj: Crystal Structure Analysis of APP E2 domain
Classification: PROTEIN FIBRIL
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2 Å
Deposited: 2010-07-15
Authors: Ha, Y., Hu, J., Lee, S., Liu, X.
PDB entry 3nyk: The structure of cobalt-substituted pseudoazurin from Alcaligenes faecalis
Classification: METAL BINDING PROTEIN
Source organism: Alcaligenes faecalis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.86 Å
Deposited: 2010-07-15
Authors: Gessmann, R., Petratos, K.
PDB entry 3nyl: The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain
Classification: CELL ADHESION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2010-07-15
Authors: Ha, Y., Hu, J., Lee, S., Liu, X., Wang, Y.
PDB entry 3nym: The crystal structure of functionally unknown protein from Neisseria meningitidis MC58
Classification: structural genomics, unknown function
Source organism: Neisseria meningitidis serogroup B
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2010-07-15
Authors: Zhang, R., Tan, K., Volkart, L., Bargassa, M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 3nyn: Crystal Structure of G Protein-Coupled Receptor Kinase 6 in Complex with Sangivamycin
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.72 Å
Deposited: 2010-07-15
Authors: Tesmer, J.J.G., Singh, P.
PDB entry 3nyo: Crystal Structure of G Protein-Coupled Receptor Kinase 6 in Complex with AMP
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.92 Å
Deposited: 2010-07-15
Authors: Tesmer, J.J.G., Singh, P.
PDB entry 3nyp: A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine ligand containing bis-3-fluoropyrrolidine end side chains
Classification: DNA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.179 Å
Deposited: 2010-07-15
Authors: Campbell, N.H., Neidle, S.
PDB entry 3nyq: Malonyl-CoA Ligase Ternary Product Complex with Methylmalonyl-CoA and AMP bound
Classification: LIGASE
Source organism: Streptomyces coelicolor
Experimental method: X-RAY DIFFRACTION
Resolution: 1.43 Å
Deposited: 2010-07-15
Authors: Hughes, A.J., Keatinge-Clay, A.T.
PDB entry 3nyr: Malonyl-CoA Ligase Ternary Product Complex with Malonyl-CoA and AMP bound
Classification: LIGASE
Source organism: Streptomyces coelicolor
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2010-07-15
Authors: Hughes, A.J., Keatinge-Clay, A.T.
PDB entry 3nys: X-ray structure of the K185A mutant of WbpE (WlbE) from pseudomonas aeruginosa in complex with PLP at 1.45 angstrom resolution
Classification: TRANSFERASE
Source organism: Pseudomonas aeruginosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2010-07-15
Authors: Holden, H.M., Thoden, J.B.
PDB entry 3nyt: X-ray crystal structure of the WlbE (WpbE) aminotransferase from pseudomonas aeruginosa, mutation K185A, in complex with the PLP external aldimine adduct with UDP-3-amino-2-N-acetyl-glucuronic acid, at 1.3 angstrom resolution
Classification: TRANSFERASE
Source organism: Pseudomonas aeruginosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.301 Å
Deposited: 2010-07-15
Authors: Holden, H.M., Thoden, J.B.
PDB entry 3nyu: X-ray crystal structure of the Wbpe (WlbE) aminotransferase from pseudomonas aeruginosa as the PLP internal aldimine adduct with lysine 185
Classification: TRANSFERASE
Source organism: Pseudomonas aeruginosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.501 Å
Deposited: 2010-07-15
Authors: Holden, H.M., Thoden, J.B.
PDB entry 3nyv: Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with non-specific inhibitor WHI-P180
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Toxoplasma gondii
Experimental method: X-RAY DIFFRACTION
Resolution: 1.88 Å
Deposited: 2010-07-15
Authors: Larson, E.T., Merritt, E.A., Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
PDB entry 3nyw: Crystal Structure of a betaketoacyl-[ACP] reductase (FabG) from Bacteroides thetaiotaomicron
Classification: OXIDOREDUCTASE
Source organism: Bacteroides thetaiotaomicron
Experimental method: X-RAY DIFFRACTION
Resolution: 2.16 Å
Deposited: 2010-07-15
Authors: Satyanarayana, L., Burley, S.K., Swaminathan, S., New York SGX Research Center for Structural Genomics (NYSGXRC)
PDB entry 3nyx: Non-phosphorylated TYK2 JH1 domain with Quinoline-Thiadiazole-Thiophene Inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2010-07-15
Authors: Eigenbrot, C., Ultsch, M.
PDB entry 3nyy: Crystal structure of a putative glycyl-glycine endopeptidase lytM (RUMGNA_02482) from Ruminococcus gnavus ATCC 29149 at 1.60 A resolution
Classification: HYDROLASE
Source organism: Ruminococcus gnavus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2010-07-15
Authors: Joint Center for Structural Genomics (JCSG)
PDB entry 3nyz: Crystal Structure of Kemp Elimination Catalyst 1A53-2
Classification: LYASE
Source organism: Sulfolobus solfataricus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.514 Å
Deposited: 2010-07-15
Authors: Lee, T.M., Privett, H.K., Kaiser, J.T., Mayo, S.L.
PDB entry 3nz0: Non-phosphorylated TYK2 kinase with CMP6
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2010-07-15
Authors: Eigenbrot, C., Ultsch, M.
PDB entry 3nz1: Crystal Structure of Kemp Elimination Catalyst 1A53-2 Complexed with Transition State Analog 5-Nitro Benzotriazole
Classification: LYASE
Source organism: Sulfolobus solfataricus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.56 Å
Deposited: 2010-07-15
Authors: Lee, T.M., Privett, H.K., Kaiser, J.T., Mayo, S.L.
PDB entry 3nz2: Crystal Structure of Hexapeptide-Repeat containing-Acetyltransferase VCA0836 Complexed with Acetyl Co Enzyme A from Vibrio cholerae O1 biovar eltor
Classification: TRANSFERASE
Source organism: Vibrio cholerae O1 biovar eltor
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2010-07-15
Authors: Kim, Y., Maltseva, N., Hasseman, J., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 3nz3: Crystal structure of the mucin-binding domain of Spr1345 from Streptococcus pneumoniae
Classification: CELL ADHESION
Source organism: Streptococcus pneumoniae
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2010-07-15
Authors: Du, Y., He, Y.-X., Zhang, Z.-Y., Yang, Y.-H., Shi, W.-W., Frolet, C., Guilmi, A.M., Vernet, T., Zhou, C.-Z., Chen, Y.
PDB entry 3nz4: Crystal Structure of a Taxus Phenylalanine Aminomutase
Classification: LYASE
Source organism: Taxus canadensis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.38 Å
Deposited: 2010-07-16
Authors: Feng, L., Geiger, J.H.
PDB entry 3nz6: Structural Analysis of Pneumocystis carinii and Human DHFR Complexes with NADPH and a Series of Five Potent 5-(omega-Carboxy(alkyloxy)Pyrido[2,3-d]pyrimidine Derivatives
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Pneumocystis carinii
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2010-07-16
Authors: Cody, V.
PDB entry 3nz7: A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine ligand containing bis-3-fluoropyrrolidine end side chains
Classification: DNA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.1 Å
Deposited: 2010-07-16
Authors: Campbell, N.H., Neidle, S.
PDB entry 3nz8: Crystal structure of the HIV-2 neutralizing Fab fragment 7C8
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2010-07-16
Authors: Uchtenhagen, H., Friemann, R., Raszewski, G., Spetz, A.-L., Nilsson, L., Achour, A.
PDB entry 3nz9: Structural Analysis of Pneumocystis carinii and Human DHFR Complexes with NADPH and a Series of Five Potent 5-(omega-Carboxy(alkyloxy)Pyrido[2,3-d]pyrimidine Derivatives
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Pneumocystis carinii
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2010-07-16
Authors: Cody, V.
PDB entry 3nza: Structural Analysis of Pneumocystis carinii and Human DHFR Complexes with NADPH and a Series of Five Potent 5-(omega-Carboxy(alkyloxy)pyrido[2,3-d]pyrimidine Derivatives
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Pneumocystis carinii
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2010-07-16
Authors: Cody, V.
PDB entry 3nzb: Structural Analysis of Pneumocystis carinii and Human DHFR Complexes with NADPH and a Series of Potent 5-(omega-carboxyl(alkyloxy)pyrido[2,-d]pyrimidine Derivatives
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Pneumocystis carinii
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2010-07-16
Authors: Cody, V.
PDB entry 3nzc: Structural Analysis of Pneumocystis carinii and Human DHFR Complexes with NADPH and a Series of Five Potent 5-(omega-carboxy(alkyloxy)pyrido[2,3-d]pyridine Derivativea
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Pneumocystis carinii
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2010-07-16
Authors: Cody, V.
PDB entry 3nzd: Structural Analysis of Pneumocystis carinii and Human DHFR Complexes with NADPH and a Series of Five 5-(omega-carboxy(alkyloxy(pyrido[2,3-d]pyrimidine Derivatives
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2010-07-16
Authors: Cody, V.
PDB entry 3nze: The crystal structure of a domain of a possible sugar-binding transcriptional regulator from Arthrobacter aurescens TC1.
Classification: Transcription regulator
Source organism: Arthrobacter aurescens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.697 Å
Deposited: 2010-07-16
Authors: Tan, K., Zhang, R., Bigelow, L., Buck, K., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 3nzg: Crystal structure of a putative racemase with Mg ion
Classification: ISOMERASE
Source organism: Pseudovibrio sp. JE062
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2010-07-16
Authors: Eswaramoorthy, S., Raparia, E., Burley, S.K., Swaminathan, S., New York SGX Research Center for Structural Genomics (NYSGXRC)
PDB entry 3nzh: Crystal structure of anti-emmprin antibody 5F6 FAB
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens, Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2010-07-16
Authors: Teplyakov, A., Obmolova, G., Malia, T., Gilliland, G.L.
PDB entry 3nzi: Substrate induced remodeling of the active site regulates HtrA1 activity
Classification: hydrolase/hydrolase substrate
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.75 Å
Deposited: 2010-07-16
Authors: Truebestein, L., Tennstaedt, A., Hauske, P., Krojer, T., Kaiser, M., Clausen, T., Ehrmann, M.
PDB entry 3nzj: Crystal structure of yeast 20S proteasome in complex with ligand 2a
Classification: hydrolase/hydrolase inhibitor
Source organism: Saccharomyces cerevisiae; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2010-07-16
Authors: Groll, M., Gallastegui, N., Marechal, X., Le Ravalec, V., Basse, N., Richy, N., Genin, E., Huber, R., Moroder, M., Vidal, V., Reboud-Ravaux, M.
PDB entry 3nzk: Structure of LpxC from Yersinia enterocolitica Complexed with CHIR090 Inhibitor
Classification: HYDROLASE
Source organism: Yersinia enterocolitica
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2010-07-16
Authors: Cole, K.E., Christianson, D.W.
PDB entry 3nzl: Crystal Structure of the N-terminal domain of DNA-binding protein SATB1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4435B
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.199 Å
Deposited: 2010-07-16
Authors: Forouhar, F., Abashidze, M., Seetharaman, J., Kuzin, A.P., Patel, P., Xiao, R., Ciccosanti, C., Shastry, R., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
PDB entry 3nzm: Crystal structure of DNAE intein with N-extein in redox trap
Classification: TRANSFERASE
Source organism: Synechocystis sp. PCC 6803
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2010-07-16
Authors: Van Roey, P., Belfort, M., Callahan, B.P.
PDB entry 3nzn: The crystal structure of the Glutaredoxin from Methanosarcina mazei Go1
Classification: OXIDOREDUCTASE
Source organism: Methanosarcina mazei
Experimental method: X-RAY DIFFRACTION
Resolution: 1.1 Å
Deposited: 2010-07-16
Authors: Zhang, R., Wu, R., Freeman, L., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 3nzp: Crystal Structure of the Biosynthetic Arginine decarboxylase SpeA from Campylobacter jejuni, Northeast Structural Genomics Consortium Target BR53
Classification: LYASE
Source organism: Campylobacter jejuni subsp. jejuni
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2010-07-16
Authors: Forouhar, F., Lew, S., Seetharaman, J., Sahdev, S., Xiao, R., Ciccosanti, C., Belote, R.L., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
PDB entry 3nzq: Crystal Structure of Biosynthetic arginine decarboxylase ADC (SpeA) from Escherichia coli, Northeast Structural Genomics Consortium Target ER600
Classification: LYASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1 Å
Deposited: 2010-07-16
Authors: Forouhar, F., Lew, S., Seetharaman, J., Sahdev, S., Xiao, R., Ciccosanti, C., Belote, R.L., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
PDB entry 3nzr: Crystal structure of 2-dehydro-3-deoxyphosphogluconate aldolase from Vibrio fischeri ES114
Classification: LYASE
Source organism: Vibrio fischeri
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2010-07-16
Authors: Nocek, B., Marshall, N., Feldmann, B., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 3nzs: Structure-based Optimization of Pyrazolo -Pyrimidine and -Pyridine Inhibitors of PI3-Kinase
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.75 Å
Deposited: 2010-07-16
Authors: Murray, J.M., Wiesmann, C.
PDB entry 3nzt: 2.0 Angstrom Crystal structure of Glutamate--Cysteine Ligase (gshA) ftom Francisella tularensis in Complex with AMP
Classification: LIGASE
Source organism: Francisella tularensis subsp. tularensis
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2010-07-16
Authors: Minasov, G., Halavaty, A., Shuvalova, L., Dubrovska, I., Winsor, J., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 3nzu: Structure-based Optimization of Pyrazolo -Pyrimidine and -Pyridine Inhibitors of PI3-Kinase
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2010-07-16
Authors: Murray, J.M., Wiesmann, C.
PDB entry 3nzw: Crystal structure of the yeast 20S proteasome in complex with 2b
Classification: hydrolase/hydrolase inhibitor
Source organism: Saccharomyces cerevisiae; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2010-07-17
Authors: Groll, M., Gallastegui, N., Marechal, X., Le Ravalec, V., Basse, N., Richy, N., Genin, E., Huber, R., Moroder, M., Vidal, V., Reboud-Ravaux, M.
PDB entry 3nzx: Crystal structure of the yeast 20S proteasome in complex with ligand 2c
Classification: hydrolase/hydrolase inhibitor
Source organism: Saccharomyces cerevisiae; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2010-07-17
Authors: Groll, M., Gallastegui, N., Marechal, X., Le Ravalec, V., Basse, N., Richy, N., Genin, E., Huber, R., Moroder, M., Vidal, V., Reboud-Ravaux, M.
PDB entry 3nzz: Crystal Structure of the Salmonella Type III Secretion System Tip Protein SipD
Classification: CELL INVASION
Source organism: Salmonella enterica
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2010-07-18
Authors: Chatterjee, S., Zhong, D., Nordhues, B.A., Battaile, K.P., Lovell, S., DeGuzman, R.N.
PDB entry 3o00: Crystal Structure of the Salmonella Type III Secretion System Tip Protein SipD-C244S
Classification: CELL INVASION
Source organism: Salmonella enterica
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2010-07-18
Authors: Chatterjee, S., Zhong, D., Nordhues, B.A., Battaile, K.P., Lovell, S., DeGuzman, R.N.
PDB entry 3o01: The Crystal Structure of the Salmonella Type III Secretion System Tip Protein SipD in Complex with Deoxycholate
Classification: CELL INVASION
Source organism: Salmonella enterica
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2010-07-18
Authors: Chatterjee, S., Zhong, D., Nordhues, B.A., Battaile, K.P., Lovell, S., DeGuzman, R.N.
PDB entry 3o02: The Crystal Structure of the Salmonella Type III Secretion System Tip Protein SipD in Complex with Chenodeoxycholate
Classification: CELL INVASION
Source organism: Salmonella enterica
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2010-07-18
Authors: Chatterjee, S., Zhong, D., Nordhues, B.A., Battaile, K.P., Lovell, S., DeGuzman, R.N.
PDB entry 3o03: Quaternary complex structure of gluconate 5-dehydrogenase from streptococcus suis type 2
Classification: OXIDOREDUCTASE
Source organism: Streptococcus suis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2010-07-18
Authors: Peng, H., Gao, F., Zhang, Q., Liu, Y., Gao, G.F.
PDB entry 3o04: Crystal structure of the beta-keto-acyl carrier protein synthase II (lmo2201) from Listeria monocytogenes
Classification: TRANSFERASE
Source organism: Listeria monocytogenes
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2010-07-19
Authors: Anderson, S.M., Wawrzak, Z., Onopriyenko, O., Anderson, W.F., Savchenko, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 3o05: Crystal Structure of Yeast Pyridoxal 5-Phosphate Synthase Snz1 Complxed with Substrate PLP
Classification: BIOSYNTHETIC PROTEIN
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2010-07-19
Authors: Teng, Y.B., Zhang, X., He, Y.X., Hu, H.X., Zhou, C.Z.
PDB entry 3o06: Crystal Structure of yeast pyridoxal 5-phosphate synthase Snz1
Classification: BIOSYNTHETIC PROTEIN
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2010-07-19
Authors: Teng, Y.B., Zhang, X., Zhou, C.Z., Hu, H.X.
PDB entry 3o07: Crystal structure of yeast pyridoxal 5-phosphate synthase Snz1 complexed with substrate G3P
Classification: BIOSYNTHETIC PROTEIN
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2010-07-19
Authors: Teng, Y.B., Zhang, X., Hu, H.X., Zhou, C.Z.