LiteFold/PDB huggingface dataset:
PDB entry 7k6c: Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium abscessus ATCC 19977 / DSM 44196 with NADP and inhibitor P218
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2020-09-19
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID), Abendroth, J., Santhakumar, V., Walpole, C., Lorimer, D.D., Horanyi, P.S., Edwards, T.E.
PDB entry 7k6d: SARS-CoV-2 Main Protease Co-Crystal Structure with Telaprevir Determined from Crystals Grown with 40 nL Acoustically Ejected Mpro Droplets at 1.48 A Resolution (Cryo-protected)
Classification: VIRAL PROTEIN, HYDROLASE/INHIBITOR
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 1.48 Å
Deposited: 2020-09-19
Authors: Kreitler, D.F., Andi, B., Kumaran, D., Soares, A.S., Shi, W., Jakoncic, J., Fuchs, M.R., Keereetaweep, J., Shanklin, J., McSweeney, S.
PDB entry 7k6e: SARS-CoV-2 Main Protease Co-Crystal Structure with Telaprevir Determined from Crystals Grown with 40 nL Acoustically Ejected Mpro Droplets at 1.63 A Resolution (Direct Vitrification)
Classification: VIRAL PROTEIN, HYDROLASE/INHIBITOR
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 1.63 Å
Deposited: 2020-09-19
Authors: Kreitler, D.F., Andi, B., Kumaran, D., Soares, A.S., Shi, W., Jakoncic, J., Fuchs, M.R., Keereetaweep, J., Shanklin, J., McSweeney, S.
PDB entry 7k6f: Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 in complex with MES (2-(N-morpholino)ethanesulfonic acid)
Classification: GENE REGULATION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.86 Å
Deposited: 2020-09-20
Authors: Karim, M.R., Bikowitz, M.J., Schonbrunn, E.
PDB entry 7k6g: Crystal structure of the first bromodomain (BD1) of human BRD4 bound to ERK5-IN-1
Classification: GENE REGULATION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2020-09-20
Authors: Karim, M.R., Zhu, J.Y., Schonbrunn, E.
PDB entry 7k6h: Crystal structure of the first bromodomain (BD1) of human BRD4 bound to XMD8-92
Classification: GENE REGULATION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2020-09-20
Authors: Karim, M.R., Zhu, J.Y., Schonbrunn, E.
PDB entry 7k6i: Carbonic Anhydrase II complexed with 4-(2-(3-phenylureido)ethylsulfonamido)benzenesulfonamide
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.406 Å
Deposited: 2020-09-20
Authors: Andring, J.T., Singh, S., McKenna, R.
PDB entry 7k6j: Carbonic Anhydrase II complexed with 4-(2-(3-(4-methylphenyl)ureido)ethylsulfonamido)benzenesulfonamide
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.755 Å
Deposited: 2020-09-20
Authors: Andring, J.T., Singh, S., McKenna, R.
PDB entry 7k6k: Carbonic Anhydrase II complexed with 4-(2-(3-(3,5-dimethylphenyl)ureido)ethylsulfonamido)benzenesulfonamide
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.306 Å
Deposited: 2020-09-20
Authors: Andring, J.T., Singh, S., McKenna, R.
PDB entry 7k6l: Carbonic Anhydrase II complexed with 4-(2-(3-(4-fluorophenyl)ureido)ethylsulfonamido)benzenesulfonamide
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.655 Å
Deposited: 2020-09-21
Authors: Andring, J.T., Singh, S., McKenna, R.
PDB entry 7k6m: Crystal structure of PI3Kalpha selective Inhibitor PF-06843195
Classification: SIGNALING PROTEIN, Transferase
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.413 Å
Deposited: 2020-09-21
Authors: Chen, P., Brooun, A., Deng, Y.L., Grodsky, N., Kaiser, S.E.
PDB entry 7k6n: Crystal structure of PI3Kalpha selective Inhibitor 11-1575
Classification: SIGNALING PROTEIN, Transferase
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.77 Å
Deposited: 2020-09-21
Authors: Chen, P., Brooun, A., Deng, Y.L., Grodsky, N., Kaiser, S.E.
PDB entry 7k6o: Crystal structure of PI3Kalpha inhibitor 10-5429
Classification: SIGNALING PROTEIN, Transferase
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.738 Å
Deposited: 2020-09-21
Authors: Chen, P., Brooun, A., Deng, Y.L., Grodsky, N., Kaiser, S.E.
PDB entry 7k6p: Active state Dot1 bound to the unacetylated H4 nucleosome
Classification: Structural Protein/DNA/Transferase
Source organism: Homo sapiens; Saccharomyces cerevisiae; Xenopus laevis; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.2 Å
Deposited: 2020-09-21
Authors: Valencia-Sanchez, M.I., De Ioannes, P.E., Miao, W., Truong, D.M., Lee, R., Armache, J.-P., Boeke, J.D., Armache, K.-J.
PDB entry 7k6q: Active state Dot1 bound to the H4K16ac nucleosome
Classification: Structural Protein/DNA/Transferase
Source organism: Homo sapiens; Saccharomyces cerevisiae; Xenopus laevis; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.1 Å
Deposited: 2020-09-21
Authors: Valencia-Sanchez, M.I., De Ioannes, P.E., Miao, W., Truong, D.M., Lee, R., Armache, J.-P., Boeke, J.D., Armache, K.-J.
PDB entry 7k6r: Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to GSK4027
Classification: GENE REGULATION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2020-09-21
Authors: Chan, A., Schonbrunn, E.
PDB entry 7k6s: Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to Compound 4 (SKT1174)
Classification: GENE REGULATION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.23 Å
Deposited: 2020-09-21
Authors: Chan, A., Schonbrunn, E.
PDB entry 7k6t: Carbonic Anhydrase IX mimic complexed with 4-(2-(3-phenylureido)ethylsulfonamido)benzenesulfonamide
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.759 Å
Deposited: 2020-09-21
Authors: Andring, J.T., Singh, S., McKenna, R.
PDB entry 7k6u: Carbonic Anhydrase IX mimic complexed with 4-(2-(3-(4-methylphenyl)ureido)ethylsulfonamido)benzenesulfonamide
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.605 Å
Deposited: 2020-09-21
Authors: Andring, J.T., Singh, S., McKenna, R.
PDB entry 7k6v: Crystal Structure of Virus-like Particles of GII.4 Norovirus Houston virus (HOV)
Classification: VIRUS LIKE PARTICLE
Source organism: Norovirus Hu/Houston/TCH186/2002/US
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2020-09-21
Authors: Hu, L., Prasad, B.V.V.
PDB entry 7k6x: Carbonic Anhydrase IX mimic complexed with 4-(2-(3-(3,5-dimethylphenyl)ureido)ethylsulfonamido)benzenesulfonamide
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.76 Å
Deposited: 2020-09-21
Authors: Andring, J.T., Singh, S., McKenna, R.
PDB entry 7k6y: Structure of the PTP-like myo-inositol phosphatase from Desulfovibrio magneticus (high salt)
Classification: HYDROLASE
Source organism: Desulfovibrio magneticus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2020-09-21
Authors: Van Herk, P.H., Cleland, C.P., Mosimann, S.C.
PDB entry 7k6z: Carbonic Anhydrase IX mimic complexed with 4-(2-(3-(4-fluorophenyl)ureido)ethylsulfonamido)benzenesulfonamide
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.657 Å
Deposited: 2020-09-21
Authors: Andring, J.T., Singh, S., McKenna, R.
PDB entry 7k71: Crystal structure of PI3Kalpha inhibitor 4-0686
Classification: SIGNALING PROTEIN, Transferase
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2020-09-21
Authors: Chen, P., Brooun, A., Deng, Y.L., Grodsky, N., Kaiser, S.E.
PDB entry 7k72: Structure of DNA ligase A from Mycobacterium tuberculosis bound to NAD
Classification: LIGASE
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2020-09-22
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 7k73: Structure of Enoyl-[acyl-carrier-protein] reductase [NADH] from Mycobacterium fortuitum bound to NAD
Classification: OXIDOREDUCTASE
Source organism: Mycolicibacterium fortuitum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2020-09-22
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 7k74: Crystal Structure of Fructose-1,6-bisphosphatase, type I, from Stenotrophomonas maltophilia K279a
Classification: HYDROLASE
Source organism: Stenotrophomonas maltophilia (strain K279a)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2020-09-22
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 7k75: Crystal structure of MAD2-6 IgA Fab in complex with PfCSP N-terminal peptide.
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2020-09-22
Authors: Pholcharee, T., Wilson, I.A.
PDB entry 7k76: Crystal structure of MAD2-6 IgG Fab in complex with PfCSP N-terminal peptide.
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.14 Å
Deposited: 2020-09-22
Authors: Pholcharee, T., Wilson, I.A.
PDB entry 7k77: The crystal structure of the 2009 H1N1 PA endonuclease mutant I38T in complex with SJ001008025
Classification: VIRAL PROTEIN
Source organism: Influenza A virus; Influenza A virus (A/Luxembourg/43/2009(H1N1))
Experimental method: X-RAY DIFFRACTION
Resolution: 2.78 Å
Deposited: 2020-09-22
Authors: Cuypers, M.G., Slavish, P.J., Rankovic, Z., White, S.W.
PDB entry 7k78: antibody and nucleosome complex
Classification: DNA BINDING PROTEIN/DNA
Source organism: Mus musculus; Saccharomyces cerevisiae; Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.1 Å
Deposited: 2020-09-22
Authors: Ruifang, G., Yawen, B.
PDB entry 7k79: CBF3
Classification: DNA BINDING PROTEIN
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: ELECTRON MICROSCOPY
Resolution: 4 Å
Deposited: 2020-09-22
Authors: Ruifang, G., Yawen, B.
PDB entry 7k7a: Transmembrane structure of TNFR1
Classification: APOPTOSIS
Source organism: Homo sapiens
Experimental method: SOLUTION NMR
Deposited: 2020-09-22
Authors: Zhao, L., Chou, J.
PDB entry 7k7b: Crystal structure of diphtheria toxin from crystals obtained at pH 5.0
Classification: TOXIN
Source organism: Corynebacterium diphtheriae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2020-09-22
Authors: Lovell, S., Kashipathy, M.M., Battaile, K.P., Rodnin, M.V., Ladokhin, A.S.
PDB entry 7k7c: Crystal structure of diphtheria toxin from crystals obtained at pH 5.5
Classification: TOXIN
Source organism: Corynebacterium diphtheriae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2020-09-22
Authors: Lovell, S., Kashipathy, M.M., Battaile, K.P., Rodnin, M.V., Ladokhin, A.S.
PDB entry 7k7d: Crystal structure of diphtheria toxin from crystals obtained at pH 6.0
Classification: TOXIN
Source organism: Corynebacterium diphtheriae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2020-09-22
Authors: Lovell, S., Kashipathy, M.M., Battaile, K.P., Rodnin, M.V., Ladokhin, A.S.
PDB entry 7k7e: Crystal structure of diphtheria toxin from crystals obtained at pH 7.0
Classification: TOXIN
Source organism: Corynebacterium diphtheriae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2020-09-22
Authors: Lovell, S., Kashipathy, M.M., Battaile, K.P., Rodnin, M.V., Ladokhin, A.S.
PDB entry 7k7f: Solution Structure of the Corynebacterium diphtheriae SpaA Pilin-Signal Peptide Complex
Classification: CELL ADHESION
Source organism: Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis); SYNTHETIC CONSTRUCT
Experimental method: SOLUTION NMR
Deposited: 2020-09-22
Authors: McConnell, S.A., Clubb, R.T.
PDB entry 7k7g: nucleosome and Gal4 complex
Classification: DNA BINDING PROTEIN/DNA
Source organism: Saccharomyces cerevisiae; Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.2 Å
Deposited: 2020-09-22
Authors: Ruifang, G., Yawen, B.
PDB entry 7k7h: Density-fitted Model Structure of Antibody Variable Domains of TyTx1 in Complex with PltB pentamer of Typhoid Toxin
Classification: TOXIN
Source organism: Mus musculus; Salmonella enterica subsp. enterica serovar Typhi str. CT18
Experimental method: ELECTRON MICROSCOPY
Resolution: 3 Å
Deposited: 2020-09-22
Authors: Nguyen, T., Feathers, J.R., Fromme, J.C., Song, J.
PDB entry 7k7i: Density-fitted Model Structure of Antibody Variable Domains of TyTx4 in Complex with PltB pentamer of Typhoid Toxin
Classification: TOXIN
Source organism: Mus musculus; Salmonella typhi
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.13 Å
Deposited: 2020-09-22
Authors: Nguyen, T., Feathers, J.R., Fromme, J.C., Song, J.
PDB entry 7k7j: EphB6 receptor ectodomain
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.004 Å
Deposited: 2020-09-22
Authors: Goldgur, Y., Himanen, J.
PDB entry 7k7k: Structure of the EPEC type III secretion injectisome EspA filament
Classification: PROTEIN TRANSPORT
Source organism: Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.56 Å
Deposited: 2020-09-23
Authors: Lyons, B.J.E., Atkinson, C.E., Strynadka, N.C.J.
PDB entry 7k7l: Structure of a hit for G Protein Coupled Receptor Kinase 2 (GRK2) Inhibitor for the Potential Treatment of Heart Failure
Classification: SIGNALING PROTEIN,TRANSFERASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.539 Å
Deposited: 2020-09-23
Authors: Spurlino, J.C., Milligan, C.
PDB entry 7k7m: Crystal Structure of a membrane protein
Classification: MEMBRANE PROTEIN
Source organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.33 Å
Deposited: 2020-09-23
Authors: Su, C.-C.
PDB entry 7k7o: CRYSTAL STRUCTURE OF TYROSINE KINASE 2 JH2 (PSEUDO KINASE DOMAIN) COMPLEXED WITH COMPOUND-12 AKA:6-[(cyclopropanecarbonyl)amino]-4-{[2-methoxy-3-(pyrimidin-2-yl)phenyl]amino}-N-methylpyridazine-3-carboxamide
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.82 Å
Deposited: 2020-09-23
Authors: Khan, J.A.
PDB entry 7k7p: Structure of SARS-CoV-2 nonstuctural protein 1
Classification: VIRAL PROTEIN
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 1.77 Å
Deposited: 2020-09-23
Authors: Green, T.J., Petit, C.M., Clark, L.K.
PDB entry 7k7q: CRYSTAL STRUCTURE OF TYROSINE KINASE 2 JH2 (PSEUDO KINASE DOMAIN) COMPLEXED WITH COMPOUND-12 AKA:6-[(cyclopropanecarbonyl)amino]-4-({3-[6-(dimethylcarbamoyl)pyridazin-3-yl]-2-methoxyphenyl}amino)-N-methylpyridazine-3-carboxamide
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.27 Å
Deposited: 2020-09-23
Authors: Khan, J.A.
PDB entry 7k7r: EBNA1 peptide AA386-405 with Fab MS39p2w174
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2020-09-23
Authors: Lanz, T.V., Robinson, W.H., Jude, K.M.
PDB entry 7k7t: Crystal structure of human MORC4 ATPase-CW in complex with AMPPNP
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.94 Å
Deposited: 2020-09-24
Authors: Klein, B.J., Tencer, A.H., Kutateladze, T.G.
PDB entry 7k7u: BetaB2-crystallin
Classification: STRUCTURAL PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.03 Å
Deposited: 2020-09-24
Authors: Tan, L.L., Jackson, C.J.
PDB entry 7k7v: The X-ray crystal structure of SSR4, an S. pombe chromatin remodelling protein: iodide derivative
Classification: GENE REGULATION
Source organism: Schizosaccharomyces pombe
Experimental method: X-RAY DIFFRACTION
Resolution: 1.882 Å
Deposited: 2020-09-24
Authors: Peat, T.S., Newman, J.
PDB entry 7k7w: The X-ray crystal structure of SSR4, an S. pombe chromatin remodelling protein: native
Classification: GENE REGULATION
Source organism: Schizosaccharomyces pombe
Experimental method: X-RAY DIFFRACTION
Resolution: 1.77 Å
Deposited: 2020-09-24
Authors: Peat, T.S., Newman, J.
PDB entry 7k7x: Solution structure of the cyclotide pase A
Classification: IMMUNOSUPPRESSANT
Source organism: Psychotria vellosiana
Experimental method: SOLUTION NMR
Deposited: 2020-09-24
Authors: Chan, L.Y., Pinto, M.E.F., Craik, D.J.
PDB entry 7k7y: Crystal structure of BoNT/E LC-HN domain in complex with VHH JLE-E9
Classification: ANTITOXIN
Source organism: Clostridium botulinum; Vicugna pacos
Experimental method: X-RAY DIFFRACTION
Resolution: 3.6 Å
Deposited: 2020-09-24
Authors: Lam, K., Jin, R.
PDB entry 7k7z: Structure of a hit for G Protein Coupled Receptor Kinase 2 (GRK2) Inhibitor for the Potential Treatment of Heart Failure
Classification: SIGNALING PROTEIN,TRANSFERASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.60609 Å
Deposited: 2020-09-24
Authors: Spurlino, J.C., Milligan, C.
PDB entry 7k80: KIR3DL1*001 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2020-09-24
Authors: MacLachlan, B.J., Rossjohn, J., Vivian, J.P.
PDB entry 7k81: KIR3DL1*005 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2020-09-24
Authors: MacLachlan, B.J., Rossjohn, J., Vivian, J.P.
PDB entry 7k82: The X-ray crystal structure of SSR4, an S. pombe chromatin remodelling protein: sulfur SAD
Classification: GENE REGULATION
Source organism: Schizosaccharomyces pombe
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2020-09-24
Authors: Peat, T.S., Newman, J.
PDB entry 7k84: Crystal structure of BoNT/E LC-HN domain in complex with VHH JLE-E5
Classification: ANTITOXIN
Source organism: Clostridium botulinum; Vicugna pacos
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2020-09-25
Authors: Lam, K., Jin, R.
PDB entry 7k86: Crystal Structure of Glutamyl-tRNA synthetase (gltX) from Stenotrophomonas maltophilia
Classification: LIGASE
Source organism: Stenotrophomonas maltophilia (strain K279a)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2020-09-25
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 7k87: The crystal structure of the 2009 H1N1 PA endonuclease in complex with SJ000986436
Classification: VIRAL PROTEIN
Source organism: Influenza A virus; Influenza A virus (A/Luxembourg/43/2009(H1N1))
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2020-09-25
Authors: Cuypers, M.G., Slavish, P.J., Jayaraman, S., Rankovic, Z., White, S.W.
PDB entry 7k88: Crystal structure of bovine RPE65 in complex with hexaethylene glycol monooctyl ether
Classification: ISOMERASE,HYDROLASE/INHIBITOR
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2020-09-26
Authors: Kiser, P.D.
PDB entry 7k89: Crystal structure of bovine RPE65 in complex with 4-fluoro-emixustat and palmitate
Classification: ISOMERASE,HYDROLASE/INHIBITOR
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2020-09-26
Authors: Kiser, P.D.
PDB entry 7k8a: CryoEM structure of a trehalose monomycolate transporter in lipid nanodiscs
Classification: TRANSLOCASE
Source organism: Mycolicibacterium smegmatis
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.65 Å
Deposited: 2020-09-26
Authors: Su, C.-C.
PDB entry 7k8b: CryoEM structure of a trehalose monomycolate transporter in lipid nanodiscs
Classification: TRANSLOCASE
Source organism: Mycolicibacterium smegmatis
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.94 Å
Deposited: 2020-09-26
Authors: Su, C.-C.
PDB entry 7k8c: CryoEM structure of a trehalose monomycolate transporter in lipid nanodiscs
Classification: TRANSLOCASE
Source organism: Mycolicibacterium smegmatis
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.27 Å
Deposited: 2020-09-26
Authors: Su, C.-C.
PDB entry 7k8d: CryoEM structure of a trehalose monomycolate transporter in TMM lipid nanodiscs (form II)
Classification: TRANSLOCASE
Source organism: Mycolicibacterium smegmatis
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.33 Å
Deposited: 2020-09-26
Authors: Su, C.-C.
PDB entry 7k8e: Beta-lactamase mixed with Ceftriaxone, 5ms
Classification: STRUCTURAL PROTEIN
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.40006 Å
Deposited: 2020-09-26
Authors: Pandey, S., Schmidt, M.
PDB entry 7k8f: Beta-lactamase mixed with Ceftriaxone, 10ms
Classification: STRUCTURAL PROTEIN
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.60003 Å
Deposited: 2020-09-26
Authors: Pandey, S., Schmidt, M.
PDB entry 7k8g: Crystal structure of bovine RPE65 in complex with 4-fluoro-MB-004 and palmitate
Classification: ISOMERASE,HYDROLASE/INHIBITOR
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2020-09-27
Authors: Kiser, P.D.
PDB entry 7k8h: Beta-lactamase mixed with Ceftriaxone, 50ms
Classification: STRUCTURAL PROTEIN
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.60006 Å
Deposited: 2020-09-27
Authors: Pandey, S., Schmidt, M.
PDB entry 7k8k: Beta-lactamase mixed with Sulbactam, 60ms
Classification: STRUCTURAL PROTEIN
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2020-09-27
Authors: Pandey, S., Schmidt, M.
PDB entry 7k8l: Beta-lactamase, Unmixed
Classification: STRUCTURAL PROTEIN
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.80001 Å
Deposited: 2020-09-27
Authors: Pandey, S., Schmidt, M.
PDB entry 7k8m: Structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment, C102
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2 Å
Deposited: 2020-09-27
Authors: Jette, C.A., Barnes, C.O., Bjorkman, P.J.
PDB entry 7k8n: Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C102
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2020-09-27
Authors: Jette, C.A., Barnes, C.O., Bjorkman, P.J.
PDB entry 7k8o: Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C002
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2020-09-27
Authors: Jette, C.A., Barnes, C.O., Bjorkman, P.J.
PDB entry 7k8p: Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C110
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2020-09-27
Authors: Dam, K.A., Barnes, C.O., Bjorkman, P.J.
PDB entry 7k8q: Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C121
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2020-09-27
Authors: Abernathy, M.E., Barnes, C.O., Bjorkman, P.J.
PDB entry 7k8r: Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C135
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2020-09-27
Authors: Jette, C.A., Barnes, C.O., Bjorkman, P.J.
PDB entry 7k8s: Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C002 (state 1)
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.4 Å
Deposited: 2020-09-27
Authors: Barnes, C.O., Malyutin, A.G., Bjorkman, P.J.
PDB entry 7k8t: Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C002 (State 2)
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.4 Å
Deposited: 2020-09-27
Authors: Malyutin, A.G., Barnes, C.O., Bjorkman, P.J.
PDB entry 7k8u: Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C104
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.8 Å
Deposited: 2020-09-27
Authors: Barnes, C.O., Malyutin, A.G., Bjorkman, P.J.
PDB entry 7k8v: Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C110
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.8 Å
Deposited: 2020-09-27
Authors: Dam, K.A., Barnes, C.O., Bjorkman, P.J.
PDB entry 7k8w: Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C119
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.6 Å
Deposited: 2020-09-27
Authors: Sharaf, N.G., Barnes, C.O., Bjorkman, P.J.
PDB entry 7k8x: Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 1)
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.9 Å
Deposited: 2020-09-27
Authors: Abernathy, M.E., Barnes, C.O., Bjorkman, P.J.
PDB entry 7k8y: Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 2)
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.4 Å
Deposited: 2020-09-27
Authors: Abernathy, M.E., Barnes, C.O., Bjorkman, P.J.
PDB entry 7k8z: Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C135
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.5 Å
Deposited: 2020-09-27
Authors: Barnes, C.O., Bjorkman, P.J.
PDB entry 7k90: Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C144
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.24 Å
Deposited: 2020-09-27
Authors: Barnes, C.O., Esswein, S.R., Bjorkman, P.J.
PDB entry 7k93: DENV2 NS1 in complex with neutralizing 2B7 single chain Fab variable region (scFv)
Classification: VIRAL PROTEIN
Source organism: Dengue virus 2; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.89 Å
Deposited: 2020-09-28
Authors: Akey, D.L., Smith, J.L.
PDB entry 7k95: Crystal structure of human CPSF30 in complex with hFip1
Classification: NUCLEAR PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2020-09-28
Authors: Hamilton, K., Tong, L.
PDB entry 7k96: Human DNA polymerase beta ternary complex with templating cytosine and incoming deoxyguanosine diphosphate
Classification: TRANSFERASE/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2020-09-28
Authors: Varela, F.A., Freudenthal, B.D.
PDB entry 7k97: Human DNA polymerase beta dGDP product complex with Mn2+
Classification: TRANSFERASE/DNA
Source organism: Homo sapiens; synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2020-09-28
Authors: Varela, F.A., Freudenthal, B.D.
PDB entry 7k98: Preaminoacylation complex of M. tuberculosis PheRS with cognate precursor tRNA and 5'-O-(N-phenylalanyl)sulfamoyl-adenosine (F-AMS)
Classification: LIGASE/RNA
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.19 Å
Deposited: 2020-09-28
Authors: Michalska, K., Chang, C., Jedrzejczak, R., Wower, J., Baragana, B., Forte, B., Gilbert, I.H., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 7k99: Crystal Structure of P. aeruginosa LpxC with N-Hydroxyformamide inhibitor 19
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2020-09-28
Authors: Sacco, M., Chen, Y.
PDB entry 7k9a: Crystal Structure of P. aeruginosa LpxC with N-Hydroxyformamide inhibitor
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2020-09-29
Authors: Sacco, M., Chen, Y.
PDB entry 7k9b: Crystal structure of Bacillus halodurans OapB (native) at 1.2 A
Classification: RNA BINDING PROTEIN
Source organism: Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.202 Å
Deposited: 2020-09-29
Authors: Yang, Y., Breaker, R.R.
PDB entry 7k9c: Crystal structure of Bacillus halodurans OapB (iodine-derivative) at 1.0 A
Classification: RNA
Source organism: Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Experimental method: X-RAY DIFFRACTION
Resolution: 1 Å
Deposited: 2020-09-29
Authors: Yang, Y., Breaker, R.R.
PDB entry 7k9d: Crystal structure of Bacillus halodurans OapB in complex with its OLE RNA target (crystal form I)
Classification: RNA-BINDING PROTEIN/RNA
Source organism: Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.098 Å
Deposited: 2020-09-29
Authors: Yang, Y., Breaker, R.R.
PDB entry 7k9e: Crystal structure of Bacillus halodurans OapB in complex with its OLE RNA target (crystal form II)
Classification: RNA-BINDING PROTEIN/RNA
Source organism: Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2020-09-29
Authors: Yang, Y., Breaker, R.R.
PDB entry 7k9h: SARS-CoV-2 Spike in complex with neutralizing Fab 2B04 (one up, two down conformation)
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Mus musculus; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.2 Å
Deposited: 2020-09-29
Authors: Errico, J.M., Fremont, D.H., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 7k9i: SARS-CoV-2 Spike RBD in complex with neutralizing Fab 2B04 (local refinement)
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Mus musculus; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.3 Å
Deposited: 2020-09-29
Authors: Errico, J.M., Fremont, D.H., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 7k9j: SARS-CoV-2 Spike in complex with neutralizing Fab 2H04 (three down conformation)
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Mus musculus; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3 Å
Deposited: 2020-09-29
Authors: Errico, J.M., Fremont, D.H., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 7k9k: SARS-CoV-2 Spike RBD in complex with neutralizing Fab 2H04 (local refinement)
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Mus musculus; Severe acute respiratory syndrome coronavirus 2
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.14 Å
Deposited: 2020-09-29
Authors: Errico, J.M., Fremont, D.H., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 7k9l: Aldolase, rabbit muscle (no beam-tilt refinement)
Classification: LYASE
Source organism: Oryctolagus cuniculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.9 Å
Deposited: 2020-09-29
Authors: Cianfrocco, M.A., Kearns, S.E., Cash, J.N., Li, Y.
PDB entry 7k9m: Crystal structure of the complex of M. tuberculosis PheRS with cognate precursor tRNA and 5'-O-(N-phenylalanyl)sulfamoyl-adenosine
Classification: LIGASE/RNA
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2020-09-29
Authors: Michalska, K., Chang, C., Jedrzejczak, R., Wower, J., Baragana, B., Forte, B., Gilbert, I.H., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 7k9n: Co-crystal structure of alpha glucosidase with compound 2
Classification: HYDROLASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.07 Å
Deposited: 2020-09-29
Authors: Karade, S.S., Mariuzza, R.A.
PDB entry 7k9o: Co-crystal structure of alpha glucosidase with compound 3
Classification: HYDROLASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.302 Å
Deposited: 2020-09-29
Authors: Karade, S.S., Mariuzza, R.A.
PDB entry 7k9p: Room temperature structure of NSP15 Endoribonuclease from SARS CoV-2 solved using SFX.
Classification: VIRAL PROTEIN
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2020-09-29
Authors: Botha, S., Jernigan, R., Chen, J., Coleman, M.A., Frank, M., Grant, T.D., Hansen, D.T., Ketawala, G., Logeswaran, D., Martin-Garcia, J., Nagaratnam, N., Raj, A.L.L.X., Shelby, M., Yang, J.-H., Yung, M.C., Fromme, P.
PDB entry 7k9q: Co-crystal structure of alpha glucosidase with compound 4
Classification: HYDROLASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2020-09-29
Authors: Karade, S.S., Mariuzza, R.A.
PDB entry 7k9r: Cryptococcus neoformans Hsp90 nucleotide binding domain
Classification: CHAPERONE
Source organism: Cryptococcus neoformans
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2020-09-29
Authors: Kuntz, D.A., Kenney, T., Prive, G.G.
PDB entry 7k9s: Cryptococcus neoformans Hsp90 nucleotide binding domain in complex with NVP-AUY922
Classification: CHAPERONE
Source organism: Cryptococcus neoformans
Experimental method: X-RAY DIFFRACTION
Resolution: 3.21 Å
Deposited: 2020-09-29
Authors: Kuntz, D.A., Prive, G.G.
PDB entry 7k9t: Co-crystal structure of alpha glucosidase with compound 5
Classification: HYDROLASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2020-09-29
Authors: Karade, S.S., Mariuzza, R.A.
PDB entry 7k9u: Cryptococcus neoformans Hsp90 nucleotide binding domain in complex with BUCMD00429
Classification: CHAPERONE
Source organism: Cryptococcus neoformans
Experimental method: X-RAY DIFFRACTION
Resolution: 1.92 Å
Deposited: 2020-09-29
Authors: Kuntz, D.A., Prive, G.G.
PDB entry 7k9v: Cryptococcus neoformans Hsp90 nucleotide binding domain in complex with BUCMD00452
Classification: CHAPERONE
Source organism: Cryptococcus neoformans
Experimental method: X-RAY DIFFRACTION
Resolution: 1.91 Å
Deposited: 2020-09-29
Authors: Kuntz, D.A., Prive, G.G.
PDB entry 7k9w: Cryptococcus neoformans Hsp90 nucleotide binding domain in complex with BUCMD00461
Classification: CHAPERONE
Source organism: Cryptococcus neoformans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.13 Å
Deposited: 2020-09-29
Authors: Kuntz, D.A., Prive, G.G.
PDB entry 7k9x: Aldolase, rabbit muscle (beam-tilt refinement x1)
Classification: LYASE
Source organism: Oryctolagus cuniculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.8 Å
Deposited: 2020-09-29
Authors: Kearns, S.K., Cash, J.N., Cianfrocco, M.A.
PDB entry 7k9y: GsI-IIC RT Template-Switching Complex (twinned)
Classification: RNA BINDING PROTEIN/RNA/DNA
Source organism: Geobacillus stearothermophilus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2 Å
Deposited: 2020-09-29
Authors: Stamos, J.L., Lentzsch, A.M.
PDB entry 7k9z: Crystal structure of SARS-CoV-2 receptor binding domain in complex with the Fab fragments of neutralizing antibodies 298 and 52
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 2.95 Å
Deposited: 2020-09-29
Authors: Newton, J.C., Kucharska, I., Rujas, E., Cui, H., Julien, J.P.
PDB entry 7ka0: Crystal structure of the complex of M. tuberculosis PheRS with cognate precursor tRNA and phenylalanine
Classification: LIGASE/RNA
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2020-09-29
Authors: Chang, C., Michalska, K., Jedrzejczak, R., Wower, J., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 7ka1: 1.60 Angstrom resolution crystal structure of the beta-Q114A mutant Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the alpha-site, aminoacrylate at the beta site, and cesium ion at the metal coordination site
Classification: LYASE/LYASE INHIBITOR
Source organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2020-09-29
Authors: Hilario, E., Dunn, M.F., Mueller, L.J.
PDB entry 7ka2: Aldolase, rabbit muscle (beam-tilt refinement x2)
Classification: LYASE
Source organism: Oryctolagus cuniculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.6 Å
Deposited: 2020-09-29
Authors: Kearns, S.K., Cash, J.N., Cianfrocco, M.A., Li, Y.
PDB entry 7ka3: Aldolase, rabbit muscle (beam-tilt refinement x3)
Classification: LYASE
Source organism: Oryctolagus cuniculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.3 Å
Deposited: 2020-09-29
Authors: Kearns, S.K., Cash, J.N., Cianfrocco, M.A., Li, Y.
PDB entry 7ka4: Aldolase, rabbit muscle (beam-tilt refinement x4)
Classification: LYASE
Source organism: Oryctolagus cuniculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.8 Å
Deposited: 2020-09-29
Authors: Kearns, S.K., Cash, J.N., Cianfrocco, M.A., Li, Y.
PDB entry 7kaa: NMR solution structures of tirasemtiv drug bound to a fast skeletal troponin C-troponin I complex
Classification: CONTRACTILE PROTEIN
Source organism: Homo sapiens
Experimental method: SOLUTION NMR
Deposited: 2020-09-30
Authors: Mercier, P., Li, M.X., Hartman, J.J., Sykes, B.D.
PDB entry 7kab: M. tuberculosis PheRS complex with cognate precursor tRNA and phenylalanine
Classification: LIGASE/RNA
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2020-09-30
Authors: Chang, C., Michalska, K., Jedrzejczak, R., Wower, J., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 7kac: Crystal structure of HPK1 (MAP4K1) kinase in complex with 5-{[4-{[(1S)-2-HYDROXY-1-PHENYLETHYL]AMINO}-5-(1,3,4-OXADIAZOL-2-YL)PYRIMIDIN-2-YL]AMINO}-3,3-DIMETHYL-2-BENZOFURAN-1(3H)-ONE
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2020-09-30
Authors: Sheriff, S.
PDB entry 7kad: Co-crystal structure of alpha glucosidase with compound 6
Classification: HYDROLASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.506 Å
Deposited: 2020-09-30
Authors: Karade, S.S., Mariuzza, R.A.
PDB entry 7kae: Rop protein variant with a buried tryptophan
Classification: RNA BINDING PROTEIN
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2020-09-30
Authors: Gallagher, D.T., Hoopes, J.T., Karageorgos, I.
PDB entry 7kaf: The crystal structure of the 2009/H1N1/California PA endonuclease I38T (construct with truncated loop 51-72) in complex with baloxavir acid
Classification: VIRAL PROTEIN
Source organism: Influenza A virus; Influenza A virus (A/Luxembourg/43/2009(H1N1))
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2020-09-30
Authors: Cuypers, M.G., Kumar, G., Slavish, J., White, S.W.
PDB entry 7kag: Crystal structure of the ubiquitin-like domain 1 (Ubl1) of Nsp3 from SARS-CoV-2
Classification: VIRAL PROTEIN
Source organism: Severe acute respiratory syndrome coronavirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 3.21 Å
Deposited: 2020-09-30
Authors: Stogios, P.J., Skarina, T., Chang, C., Kim, Y., Di Leo, R., Savchenko, A., Joachimiak, A., Satchell, K.J.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 7kah: Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class without Sec62
Classification: PROTEIN TRANSPORT
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.1 Å
Deposited: 2020-10-01
Authors: Itskanov, S., Park, E.
PDB entry 7kai: Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class with Sec62, conformation 1 (C1)
Classification: PROTEIN TRANSPORT
Source organism: Saccharomyces cerevisiae BY4741
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.2 Å
Deposited: 2020-10-01
Authors: Itskanov, S., Park, E.
PDB entry 7kaj: Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class with Sec62, conformation 2 (C2)
Classification: PROTEIN TRANSPORT
Source organism: Saccharomyces cerevisiae BY4741
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.1 Å
Deposited: 2020-10-01
Authors: Itskanov, S., Park, E.
PDB entry 7kak: Cryo-EM structure of the Sec complex from T. lanuginosus, wild-type, class without Sec62
Classification: PROTEIN TRANSPORT
Source organism: Thermomyces lanuginosus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.9 Å
Deposited: 2020-10-01
Authors: Itskanov, S., Park, E.
PDB entry 7kal: Cryo-EM structure of the Sec complex from T. lanuginosus, wild-type, class with Sec62, plug-open conformation
Classification: PROTEIN TRANSPORT
Source organism: Thermomyces lanuginosus
Experimental method: ELECTRON MICROSCOPY
Resolution: 4 Å
Deposited: 2020-10-01
Authors: Itskanov, S., Park, E.
PDB entry 7kam: Cryo-EM structure of the Sec complex from T. lanuginosus, wild-type, class with Sec62, plug-closed conformation
Classification: PROTEIN TRANSPORT
Source organism: Thermomyces lanuginosus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.8 Å
Deposited: 2020-10-01
Authors: Itskanov, S., Park, E.
PDB entry 7kan: Cryo-EM structure of the Sec complex from T. lanuginosus, Sec62-lacking mutant (Delta Sec62)
Classification: PROTEIN TRANSPORT
Source organism: Thermomyces lanuginosus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.7 Å
Deposited: 2020-10-01
Authors: Itskanov, S., Park, E.
PDB entry 7kao: Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class without Sec62
Classification: PROTEIN TRANSPORT
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: ELECTRON MICROSCOPY
Resolution: 4 Å
Deposited: 2020-10-01
Authors: Itskanov, S., Park, E.
PDB entry 7kap: Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class with Sec62, conformation 1 (C1)
Classification: PROTEIN TRANSPORT
Source organism: Saccharomyces cerevisiae BY4741
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.1 Å
Deposited: 2020-10-01
Authors: Itskanov, S., Park, E.
PDB entry 7kaq: Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class with Sec62, conformation 2 (C2)
Classification: PROTEIN TRANSPORT
Source organism: Saccharomyces cerevisiae BY4741
Experimental method: ELECTRON MICROSCOPY
Resolution: 4 Å
Deposited: 2020-10-01
Authors: Itskanov, S., Park, E.
PDB entry 7kar: Cryo-EM structure of the Sec complex from S. cerevisiae, Sec63 FN3 mutant, class without Sec62
Classification: PROTEIN TRANSPORT
Source organism: Saccharomyces cerevisiae BY4741
Experimental method: ELECTRON MICROSCOPY
Resolution: 4 Å
Deposited: 2020-10-01
Authors: Itskanov, S., Park, E.
PDB entry 7kas: Cryo-EM structure of the Sec complex from S. cerevisiae, Sec63 FN3 mutant, class with Sec62
Classification: PROTEIN TRANSPORT
Source organism: Saccharomyces cerevisiae BY4741
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.9 Å
Deposited: 2020-10-01
Authors: Itskanov, S., Park, E.
PDB entry 7kat: Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore ring and Sec63 FN3 double mutant, class without Sec62
Classification: PROTEIN TRANSPORT
Source organism: Saccharomyces cerevisiae BY4741
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.4 Å
Deposited: 2020-10-01
Authors: Itskanov, S., Park, E.
PDB entry 7kau: Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore ring and Sec63 FN3 double mutant, class with Sec62
Classification: PROTEIN TRANSPORT
Source organism: Saccharomyces cerevisiae BY4741
Experimental method: ELECTRON MICROSCOPY
Resolution: 4 Å
Deposited: 2020-10-01
Authors: Itskanov, S., Park, E.
PDB entry 7kav: Crystal structure of OhyA-PEG400 complex from Staphylococcus aureus
Classification: OXIDOREDUCTASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.843 Å
Deposited: 2020-10-01
Authors: Radka, C.D., Rock, C.O.
PDB entry 7kaw: Crystal structure of OhyA-PEG400-FAD complex from Staphylococcus aureus
Classification: OXIDOREDUCTASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.105 Å
Deposited: 2020-10-01
Authors: Radka, C.D., Rock, C.O.
PDB entry 7kax: Crystal structure of OhyA(E82A) from Staphylococcus aureus
Classification: OXIDOREDUCTASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.514 Å
Deposited: 2020-10-01
Authors: Radka, C.D., Rock, C.O.
PDB entry 7kay: Crystal structure of OhyA(E82A)-18:1 complex from Staphylococcus aureus
Classification: OXIDOREDUCTASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2020-10-01
Authors: Radka, C.D., Rock, C.O.
PDB entry 7kaz: Crystal structure of OhyA(E82A)-18:1/h18:0-FAD complex from Staphylococcus aureus
Classification: OXIDOREDUCTASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.854 Å
Deposited: 2020-10-01
Authors: Radka, C.D., Rock, C.O.
PDB entry 7kb0: O-acety-L-homoserine aminocarboxypropyltransferase (MetY) from Thermotoga maritima with pyridoxal-5-phosphate (PLP) bound in the internal aldimine state
Classification: TRANSFERASE
Source organism: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2020-10-01
Authors: Brewster, J.L., Pachl, P., Squire, C., Selmer, M., Patrick, W.M.