LiteFold/PDB huggingface dataset:
PDB entry 8t5d: Cryo-EM studies of the interplay between uS2 ribosomal protein and leaderless mRNA during bacterial translation initiation
Classification: RIBOSOME
Source organism: Bacteriophage sp.; Escherichia coli
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.2 Å
Deposited: 2023-06-13
Authors: Bhattacharjee, S., Gottesman, M.E., Frank, J.
PDB entry 8t5e: De novo design of high-affinity protein binders to bioactive helical peptides
Classification: DE NOVO PROTEIN
Source organism: synthetic construct; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2023-06-13
Authors: Torres, S.V., Leung, P.J.Y., Bera, A.K., Baker, D., Kang, A.
PDB entry 8t5f: De novo design of high-affinity protein binders to bioactive helical peptides
Classification: DE NOVO PROTEIN
Experimental method: X-RAY DIFFRACTION
Resolution: 1.99 Å
Deposited: 2023-06-13
Authors: Torres, S.V., Leung, P.J.Y., Bera, A.K., Baker, D., Kang, A.
PDB entry 8t5g: SOS2 co-crystal structure with fragment bound (compound 12)
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.92 Å
Deposited: 2023-06-13
Authors: Gunn, R.J., Lawson, J.D., Ivetac, A., Ulaganathan, T., Coulombe, R., Fethiere, J.
PDB entry 8t5h: Cryo-EM studies of the interplay between uS2 ribosomal protein and leaderless mRNA during bacterial translation initiation
Classification: RIBOSOME
Source organism: Bacteriophage sp.; Escherichia coli
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.3 Å
Deposited: 2023-06-13
Authors: Bhattacharjee, S., Gottesman, M.E., Frank, J.
PDB entry 8t5i: Crystal structure of human WDR5 in complex with MR4397
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2023-06-13
Authors: Kimani, S., Dong, A., Li, F., Loppnau, P., Ackloo, S., Vedadi, M., Brown, P.J., Arrowsmith, C.H., Edwards, A.M., Halabelian, L., Structural Genomics Consortium (SGC)
PDB entry 8t5j: Crystal structure of outer membrane lipoprotein carrier protein (LolA) from Francisella philomiragia
Classification: LIPID TRANSPORT
Source organism: Francisella philomiragia
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2023-06-13
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 8t5k: Crystal structure of STING CTD in complex with BDW-OH
Classification: ANTIVIRAL PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2023-06-13
Authors: Li, Y., Li, P., Sun, D.
PDB entry 8t5l: Crystal structure of STING CTD in complex with 2'3'-cGAMP
Classification: ANTIVIRAL PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.01 Å
Deposited: 2023-06-13
Authors: Li, Y., Li, P., Sun, D.
PDB entry 8t5m: SOS2 crystal structure with fragment bound (compound 14)
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.79 Å
Deposited: 2023-06-14
Authors: Gunn, R.J., Lawson, J.D., Ivetac, A., Ulaganathan, T., Coulombe, R., Fethiere, J.
PDB entry 8t5n: Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (AMP-Mg bound)
Classification: LIGASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2023-06-14
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 8t5o: Cryo-EM structure of RNA device 43, holo state
Classification: RNA
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.98 Å
Deposited: 2023-06-14
Authors: Stagno, J.R., Deme, J.C., Lee, Y.-T., Wang, Y.-X., Lea, S.M.
PDB entry 8t5p: SARS-CoV-2 ORF3a peptide in complex with TRAF3 TRAF domain
Classification: SIGNALING PROTEIN/VIRAL PROTEIN
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2023-06-14
Authors: Busscher, B.M., Xiao, T.S.
PDB entry 8t5q: SARS-CoV-2 ORF3a peptide in complex with TRAF2 TRAF domain
Classification: SIGNALING PROTEIN/VIRAL PROTEIN
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2023-06-14
Authors: Busscher, B.M., Xiao, T.S.
PDB entry 8t5r: SOS2 crystal structure with fragment bound (compound 13)
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.12 Å
Deposited: 2023-06-14
Authors: Gunn, R.J., Lawson, J.D., Ivetac, A., Ulaganathan, T., Coulombe, R., Fethiere, J.
PDB entry 8t5s: Cryo-EM structure of DRH-1 helicase and C-terminal domain bound to dsRNA
Classification: ANTIVIRAL PROTEIN/RNA
Source organism: Caenorhabditis elegans; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.9 Å
Deposited: 2023-06-14
Authors: Consalvo, C.D., Donelick, H.M., Shen, P.S., Bass, B.L.
PDB entry 8t5t: Crystal structure of outer membrane lipoprotein carrier protein (LolA) from Borrelia burgdorferi (steric acid bound)
Classification: LIPID TRANSPORT
Source organism: Borreliella burgdorferi B31
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2023-06-14
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 8t5u: ATP-1 state of Bcs1 (C7 symmetrized)
Classification: TRANSLOCASE
Source organism: Mus musculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.13 Å
Deposited: 2023-06-14
Authors: Zhan, J., Xia, D.
PDB entry 8t5v: Influenza PA-N Endonuclease A36V mutant with Baloxavir
Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR
Source organism: Influenza A virus (A/California/04/2009(H1N1))
Experimental method: X-RAY DIFFRACTION
Resolution: 1.79 Å
Deposited: 2023-06-14
Authors: Kohlbrand, A.J., Cohen, S.M.
PDB entry 8t5w: Influenza PAN endonuclease I38T mutant with Baloxavir
Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR
Source organism: Influenza A virus (A/California/04/2009(H1N1))
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2023-06-14
Authors: Kohlbrand, A.J., Cohen, S.M.
PDB entry 8t5x: Probing the dissociation pathway of a kinetically labile transthyretin mutant (A25T)
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.63 Å
Deposited: 2023-06-14
Authors: Ferguson, J.A., Sun, X., Leach, B.I., Stanfield, R.L., Dyson, H.J., Wright, P.E.
PDB entry 8t5y: Structure of Rhodococcus sp. USK13 DarR(K44A)-cAMP complex
Classification: TRANSCRIPTION
Source organism: Rhodococcus sp. USK13
Experimental method: X-RAY DIFFRACTION
Resolution: 1.44 Å
Deposited: 2023-06-14
Authors: Schumacher, M.A.
PDB entry 8t5z: Influenza PA-N Endonuclease (amino acids 52-74 truncation)
Classification: VIRAL PROTEIN,HYDROLASE
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.03 Å
Deposited: 2023-06-14
Authors: Kohlbrand, A.J., Cohen, S.M.
PDB entry 8t60: CryoEM structure of an inward-facing MelBSt at a Na(+)-bound and sugar low-affinity conformation
Classification: TRANSPORT PROTEIN
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium; synthetic construct
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.29 Å
Deposited: 2023-06-14
Authors: Guan, L.
PDB entry 8t61: Solution NMR structure of designed peptide BH33 (RHYYKFNSTGRHYHYY)
Classification: DE NOVO PROTEIN
Experimental method: SOLUTION NMR
Deposited: 2023-06-15
Authors: McShan, A.C., Torres, M.P.
PDB entry 8t62: Solution NMR structure of designed peptide BH21 (TMIEDPEAGHFHTSSA)
Classification: DE NOVO PROTEIN
Experimental method: SOLUTION NMR
Deposited: 2023-06-15
Authors: McShan, A.C., Torres, M.P.
PDB entry 8t63: Solution NMR structure of designed peptide PH1 (WHMWNTVPNAKQVIAA)
Classification: DE NOVO PROTEIN
Experimental method: SOLUTION NMR
Deposited: 2023-06-15
Authors: McShan, A.C., Torres, M.P.
PDB entry 8t64: Apo Cam1(42-206)
Classification: IMMUNE SYSTEM
Source organism: Nitrosococcus halophilus Nc 4
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2023-06-15
Authors: Yu, Y., Patel, D.J.
PDB entry 8t65: cA4 bound Cam1
Classification: ANTIVIRAL PROTEIN/RNA
Source organism: Nitrosococcus halophilus Nc 4; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.09 Å
Deposited: 2023-06-15
Authors: Yu, Y., Patel, D.J.
PDB entry 8t66: cA6 bound Cam1
Classification: IMMUNE SYSTEM/RNA
Source organism: Nitrosococcus halophilus Nc 4; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2023-06-15
Authors: Yu, Y., Patel, D.J.
PDB entry 8t67: Influenza PA-N Endonuclease I38T Mutant (amino acids 52-74 truncation)
Classification: VIRAL PROTEIN,HYDROLASE
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.08 Å
Deposited: 2023-06-15
Authors: Kohlbrand, A.J., Cohen, S.M.
PDB entry 8t68: Crystal Structure of the SET Domain of Human Histone-Lysine N-Methyltransferase SUV420H1 in complex with RQ3-111
Classification: TRANSPORT PROTEIN,TRANSFERASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2023-06-15
Authors: Zeng, H., Dong, A., Brown, P.J., Arrowsmith, C.H., Edwards, A.M., Halabelian, L., Structural Genomics Consortium (SGC)
PDB entry 8t69: Human VMAT2 in complex with tetrabenazine
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.89 Å
Deposited: 2023-06-15
Authors: Pidathala, S., Dai, Y., Lee, C.H.
PDB entry 8t6a: Human VMAT2 in complex with reserpine
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.17 Å
Deposited: 2023-06-15
Authors: Pidathala, S., Dai, Y., Lee, C.H.
PDB entry 8t6b: Human VMAT2 in complex with serotonin
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.72 Å
Deposited: 2023-06-15
Authors: Pidathala, S., Dai, Y., Lee, C.H.
PDB entry 8t6c: Crystal structure of T33-18.2: Deep-learning sequence design of co-assembling tetrahedron protein nanoparticles
Classification: DE NOVO PROTEIN
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 1.92 Å
Deposited: 2023-06-15
Authors: Bera, A.K., de Haas, R.J., Kang, A., Sankaran, B., King, N.P.
PDB entry 8t6d: Identification of GDC-1971 (RLY-1971), a SHP2 inhibitor designed for the treatment of solid tumors
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2023-06-15
Authors: Tang, Y., Nguyen, V., Wilbur, J.D.
PDB entry 8t6e: Crystal structure of T33-28.3: Deep-learning sequence design of co-assembling tetrahedron protein nanoparticles
Classification: DE NOVO PROTEIN
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 2.48 Å
Deposited: 2023-06-15
Authors: Bera, A.K., de Haas, R.J., Kang, A., Sankaran, B., King, N.P.
PDB entry 8t6f: Crystal structure of human MBP-Myeloid cell leukemia 1 (Mcl-1) in complex with BRD810 inhibitor
Classification: APOPTOSIS
Source organism: Escherichia coli K-12; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.56 Å
Deposited: 2023-06-15
Authors: Poncet-Montange, G., Lemke, C.T.
PDB entry 8t6g: Identification of GDC-1971 (RLY-1971), a SHP2 inhibitor designed for the treatment of solid tumors
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.84 Å
Deposited: 2023-06-15
Authors: Tang, Y., Nugyen, V., Wilbur, J.D.
PDB entry 8t6h: X-ray crystal structure of PfA-M1(E319A)
Classification: HYDROLASE
Source organism: Plasmodium falciparum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.981 Å
Deposited: 2023-06-16
Authors: Webb, C.T., McGowan, S.
PDB entry 8t6i: Structure of VHH-Fab complex with engineered Crystal Kappa region
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.55 Å
Deposited: 2023-06-16
Authors: Filippova, E.V., Thompson, I., Kossiakoff, A.A.
PDB entry 8t6j: CDPPB-bound inactive mGlu5
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.5 Å
Deposited: 2023-06-16
Authors: Krishna Kumar, K., Wang, H., Kobilka, B.K.
PDB entry 8t6k: Cryo-EM structure of tetradecameric CaMKII beta holoenzyme T287A T306A T307A
Classification: SIGNALING PROTEIN
Source organism: Aequorea victoria; Rattus norvegicus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3 Å
Deposited: 2023-06-16
Authors: Chien, C.-T., Chiu, W., Khan, S.
PDB entry 8t6l: Cryo-EM structure of rat cardiac sodium channel NaV1.5 with batrachotoxin analog BTX-B
Classification: MEMBRANE PROTEIN
Source organism: Aequorea victoria; Rattus norvegicus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.3 Å
Deposited: 2023-06-16
Authors: Tonggu, L., Wisedchaisri, G., Gamal El-Din, T.M., Zheng, N., Catterall, W.A.
PDB entry 8t6m: Human leukocyte antigen bound by two alloreactive antibody Fabs
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.14 Å
Deposited: 2023-06-16
Authors: Kizziah, J.L., Killian, J.T., Diaz-Avalos, R., Qiu, S., Yang, G., Green, T., Lund, F.E.
PDB entry 8t6n: Crystal structure of T33-27.1: Deep-learning sequence design of co-assembling tetrahedron protein nanoparticles
Classification: DE NOVO PROTEIN
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 3.63 Å
Deposited: 2023-06-16
Authors: Bera, A.K., de Haas, R.J., Kang, A., Sankaran, B., King, N.P.
PDB entry 8t6o: SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 0 bp R-loop
Classification: IMMUNE SYSTEM
Source organism: Streptococcus pyogenes; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.1 Å
Deposited: 2023-06-16
Authors: Hibshman, G.N., Bravo, J.P.K., Taylor, D.W.
PDB entry 8t6p: SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 2 bp R-loop
Classification: IMMUNE SYSTEM
Source organism: Streptococcus pyogenes; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.15 Å
Deposited: 2023-06-16
Authors: Hibshman, G.N., Bravo, J.P.K., Taylor, D.W.
PDB entry 8t6q: Cryo-EM structure of dodecameric CaMKII beta holoenzyme T287A T306A T307A
Classification: SIGNALING PROTEIN
Source organism: Aequorea victoria; Rattus norvegicus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.5 Å
Deposited: 2023-06-16
Authors: Chien, C.-T., Chiu, W., Khan, S.
PDB entry 8t6r: Acinetobacter baumannii 118362 family 2A cargo-loaded encapsulin shell
Classification: VIRUS LIKE PARTICLE
Source organism: Acinetobacter baumannii 118362
Experimental method: ELECTRON MICROSCOPY
Resolution: 1.78 Å
Deposited: 2023-06-17
Authors: Andreas, M.P., Benisch, R., Giessen, T.W.
PDB entry 8t6s: SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 10 bp R-loop
Classification: IMMUNE SYSTEM
Source organism: Streptococcus pyogenes; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.28 Å
Deposited: 2023-06-18
Authors: Hibshman, G.N., Bravo, J.P.K., Taylor, D.W.
PDB entry 8t6t: SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 13 bp R-loop
Classification: IMMUNE SYSTEM
Source organism: Streptococcus pyogenes; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.04 Å
Deposited: 2023-06-18
Authors: Hibshman, G.N., Bravo, J.P.K., Taylor, D.W.
PDB entry 8t6u: Cryo-EM structure of human Anion Exchanger 1 bound to Dipyridamole
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.13 Å
Deposited: 2023-06-18
Authors: Capper, M.J., Zilberg, G., Mathiharan, Y.K., Yang, S., Stone, A.C., Wacker, D.
PDB entry 8t6v: Cryo-EM structure of human Anion Exchanger 1 bound to 4,4'-Diisothiocyanatostilbene-2,2'-Disulfonic Acid (DIDS)
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.95 Å
Deposited: 2023-06-18
Authors: Capper, M.J., Zilberg, G., Mathiharan, Y.K., Yang, S., Stone, A.C., Wacker, D.
PDB entry 8t6x: SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 18 bp R-loop
Classification: IMMUNE SYSTEM
Source organism: Streptococcus pyogenes; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.08 Å
Deposited: 2023-06-19
Authors: Hibshman, G.N., Bravo, J.P.K., Taylor, D.W.
PDB entry 8t6y: SpRY-Cas9:gRNA complex bound to non-target DNA with 1 bp R-loop
Classification: IMMUNE SYSTEM
Source organism: Streptococcus pyogenes; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.88 Å
Deposited: 2023-06-19
Authors: Hibshman, G.N., Bravo, J.P.K., Taylor, D.W.
PDB entry 8t6z: Influenza PAN endonuclease I38T mutant with 6-(4-(1H-tetrazol-5-yl)-2-(trifluoromethyl)phenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid
Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.91 Å
Deposited: 2023-06-19
Authors: Kohlbrand, A.J., Cohen, S.M.
PDB entry 8t70: Cryptococcus neoformans protein farnesyltransferase in complex with FPTII and TKCMIIM peptide
Classification: TRANSFERASE
Source organism: Cryptococcus neoformans; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.892 Å
Deposited: 2023-06-19
Authors: Wang, Y., Beese, L.S.
PDB entry 8t71: Crystal Structure of WT KRAS4a with bound GDP and Mg ion
Classification: ONCOPROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2023-06-19
Authors: Tran, T.H., Whitley, M.J., Dharmaiah, S., Simanshu, D.K.
PDB entry 8t72: Crystal structure of WT KRAS4a with bound GMPPNP and Mg ion
Classification: ONCOPROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2023-06-19
Authors: Tran, T.H., Whitley, M.J., Dharmaiah, S., Simanshu, D.K.
PDB entry 8t73: Crystal structure of KRAS4a-R151G with bound GDP and Mg ion
Classification: ONCOPROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2023-06-19
Authors: Tran, T.H., Whitley, M.J., Dharmaiah, S., Simanshu, D.K.
PDB entry 8t74: Crystal structure of KRAS4a (GMPPNP) in complex with RAF1 (RBD)
Classification: ONCOPROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2023-06-19
Authors: Whitley, M.J., Simanshu, D.K.
PDB entry 8t75: Crystal Structure of KRAS4a (GMPPNP) in complex with RAF1 (RBD-CRD)
Classification: ONCOPROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.65 Å
Deposited: 2023-06-19
Authors: Whitley, M.J., Simanshu, D.K.
PDB entry 8t76: SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 3 bp R-loop
Classification: IMMUNE SYSTEM
Source organism: Streptococcus pyogenes; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.42 Å
Deposited: 2023-06-19
Authors: Hibshman, G.N., Bravo, J.P.K., Taylor, D.W.
PDB entry 8t77: SpRY-Cas9:gRNA complex bound to non-target DNA with 6 bp R-loop
Classification: IMMUNE SYSTEM
Source organism: Streptococcus pyogenes; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.25 Å
Deposited: 2023-06-19
Authors: Hibshman, G.N., Bravo, J.P.K., Taylor, D.W.
PDB entry 8t78: SpRY-Cas9:gRNA complex bound to non-target DNA with 8 bp R-loop
Classification: IMMUNE SYSTEM
Source organism: Streptococcus pyogenes; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.02 Å
Deposited: 2023-06-19
Authors: Hibshman, G.N., Bravo, J.P.K., Taylor, D.W.
PDB entry 8t79: SpRY-Cas9:gRNA complex bound to non-target DNA with 10 bp R-loop
Classification: IMMUNE SYSTEM
Source organism: Streptococcus pyogenes; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.04 Å
Deposited: 2023-06-20
Authors: Hibshman, G.N., Bravo, J.P.K., Taylor, D.W.
PDB entry 8t7a: Cryo-EM structure of RSV preF in complex with Fab 2.4K
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Respiratory syncytial virus
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.8 Å
Deposited: 2023-06-20
Authors: McCool, R.S., McLellan, J.S.
PDB entry 8t7b: Sequence specific (AATT) orientation of netropsin molecules at a unique minor groove binding site (position2) within a self-assembled 3D DNA lattice (4x5)
Classification: DNA
Experimental method: X-RAY DIFFRACTION
Resolution: 3.05 Å
Deposited: 2023-06-20
Authors: Simmons, C.R., MacCulloch, T., Stephanopoulos, N., Yan, H.
PDB entry 8t7c: Crystal structure of human phospholipase C gamma 2
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.55 Å
Deposited: 2023-06-20
Authors: Chen, Y., Choi, H., Zhuang, N., Hu, L., Qian, D., Wang, J.
PDB entry 8t7d: Crystal structure of wild type IDH1 bound to compound 1
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.444 Å
Deposited: 2023-06-20
Authors: Lu, J., Abeywickrema, P., Heo, M.R., Parthasarathy, G., McCoy, M., Soisson, S.M.
PDB entry 8t7e: Cryo-EM structure of the Backtracking Initiation Complex (VII) of Human Mitochondrial DNA Polymerase Gamma
Classification: Transferase/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.08 Å
Deposited: 2023-06-20
Authors: Nayak, A.R., Buchel, G., Herbine, K.H., Sarfallah, A., Sokolova, V.O., Zamudio-Ochoa, A., Temiakov, D.
PDB entry 8t7f: Structure of the S1 variant of Fab F1
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.5 Å
Deposited: 2023-06-20
Authors: Singer, A.U., Bruce, H.A., Enderle, L., Blazer, L., Adams, J.J., Sicheri, F., Sidhu, S.S.
PDB entry 8t7g: Structure of the CK variant of Fab F1 (FabC-F1)
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2023-06-20
Authors: Singer, A.U., Bruce, H.A., Blazer, L., Adams, J.J., Sicheri, F., Sidhu, S.S.
PDB entry 8t7h: Quis-bound intermediate mGlu5
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens; Lama glama
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.3 Å
Deposited: 2023-06-20
Authors: Krishna Kumar, K., Wang, H., Kobilka, B.K.
PDB entry 8t7i: Structure of the S1CE variant of Fab F1 (FabS1CE-F1)
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2023-06-20
Authors: Singer, A.U., Bruce, H.A., Enderle, L., Blazer, L., Adams, J.J., Sicheri, F., Sidhu, S.S.
PDB entry 8t7j: Oxygen- and PLP-dependent Cap15 holoenzyme bound with phosphate anion
Classification: BIOSYNTHETIC PROTEIN
Source organism: Streptomyces sp. SANK 62799
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2023-06-20
Authors: Daniel-Ivad, P., Ryan, K.S.
PDB entry 8t7k: Apo HftA from Treponema denticola
Classification: METAL BINDING PROTEIN
Source organism: Treponema denticola ATCC 35405
Experimental method: X-RAY DIFFRACTION
Resolution: 1.78 Å
Deposited: 2023-06-20
Authors: Corbett, B.W., Suits, M.D.
PDB entry 8t7l: Copper bound HftA from Treponema denticola
Classification: METAL BINDING PROTEIN
Source organism: Treponema denticola ATCC 35405
Experimental method: X-RAY DIFFRACTION
Resolution: 1.89 Å
Deposited: 2023-06-20
Authors: Corbett, B.W., Suits, M.D.
PDB entry 8t7m: Iron and Copper bound HftA from Treponema denticola
Classification: METAL BINDING PROTEIN
Source organism: Treponema denticola ATCC 35405
Experimental method: X-RAY DIFFRACTION
Resolution: 1.82 Å
Deposited: 2023-06-20
Authors: Corbett, B.W., Suits, M.D.
PDB entry 8t7n: Crystal structure of the R132H mutant of IDH1 bound to compound 1
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.26 Å
Deposited: 2023-06-20
Authors: Lu, J., Abeywickrema, P., Heo, M.R., Parthasarathy, G., McCoy, M., Soisson, S.M.
PDB entry 8t7o: Crystal structure of the R132H mutant of IDH1 bound to AG-120
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.053 Å
Deposited: 2023-06-20
Authors: Lu, J., Abeywickrema, P., Heo, M.R., Parthasarathy, G., McCoy, M., Soisson, S.M.
PDB entry 8t7p: X-ray crystal structure of PfA-M1(M462S)
Classification: HYDROLASE
Source organism: Plasmodium falciparum
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2023-06-21
Authors: Yang, W., Drinkwater, N., Webb, C.T., McGowan, S.
PDB entry 8t7q: Identification of GDC-1971 (RLY-1971), a SHP2 inhibitor designed for the treatment of solid tumors
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2023-06-21
Authors: Tang, Y., Nguyen, V., Wilbur, J.D.
PDB entry 8t7r: Crystal structure of human leukocyte antigen A*0101 in complex with the Fab of alloreactive antibody E07
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.84 Å
Deposited: 2023-06-21
Authors: Green, T.J., Killian Jr, J.T., Qiu, S., Macon, K.J., Yang, G., King, R.G., Lund, F.E.
PDB entry 8t7s: SpRYmer bound to NAC PAM DNA
Classification: IMMUNE SYSTEM
Source organism: Streptococcus pyogenes; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.01 Å
Deposited: 2023-06-21
Authors: Hibshman, G.N., Bravo, J.P.K., Taylor, D.W.
PDB entry 8t7t: CryoEM structure of the HisRS-like domain of human GCN2
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.2 Å
Deposited: 2023-06-21
Authors: Yin, J.Z., Keszei, A.F.A., Mazhab-Jafari, M.T., Sicheri, F.
PDB entry 8t7u: ADP-bound Bcs1 (unsymmetrized)
Classification: TRANSLOCASE
Source organism: Mus musculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.74 Å
Deposited: 2023-06-21
Authors: Zhan, J., Xia, D.
PDB entry 8t7v: Co-crystal structure of KRIT1 with a 1-hydroxy 2-naphthaldehyde derivative (6-(furan-2-yl)-2-hydroxy-1-naphthaldehyde)
Classification: CELL ADHESION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2023-06-21
Authors: Bruystens, J.G.H.
PDB entry 8t7w: Crystal structure of Oxygen-dependent coproporphyrinogen-III oxidase (hemF) from Klebsiella aerogenes
Classification: OXIDOREDUCTASE
Source organism: Klebsiella aerogenes KCTC 2190
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2023-06-21
Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 8t7x: Sequence specific (AATT) orientation of DAPI molecules at two unique minor groove binding sites within a self-assembled 3D DNA lattice (4x5)
Classification: DNA
Experimental method: X-RAY DIFFRACTION
Resolution: 3.07 Å
Deposited: 2023-06-21
Authors: Simmons, C.R., MacCulloch, T., Stephanopoulos, N., Yan, H.
PDB entry 8t7y: Structure of SARS CoV-2 main protease in complex with Chymostatin.
Classification: CELL INVASION
Source organism: Severe acute respiratory syndrome coronavirus 2; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.78 Å
Deposited: 2023-06-21
Authors: Terzyan, S., Yarla, N., Rao, C.V., Mooers, B.
PDB entry 8t7z: Crystal structure of alpha-glucosidase (yicI) from Klebsiella aerogenes
Classification: HYDROLASE
Source organism: Klebsiella aerogenes KCTC 2190
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2023-06-21
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 8t80: Sequence specific (AATT) orientation of Hoechst molecules at two unique minor groove binding sites within a self-assembled 3D DNA lattice (4x5)
Classification: DNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.91 Å
Deposited: 2023-06-21
Authors: Simmons, C.R., MacCulloch, T., Stephanopoulos, N., Yan, H.
PDB entry 8t81: Influenza PAN endonuclease E23K mutant with 6-(4-(1H-tetrazol-5-yl)-2-(trifluoromethyl)phenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid
Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2023-06-21
Authors: Kohlbrand, A.J., Cohen, S.M.
PDB entry 8t82: Racemic mixture of amyloid beta segment 35-MVGGVV-40 forms heterochiral rippled beta-sheet, includes pentafluoropropionic acid
Classification: PROTEIN FIBRIL
Experimental method: X-RAY DIFFRACTION
Resolution: 1.1 Å
Deposited: 2023-06-21
Authors: Sawaya, M.R., Raskatov, J.A., Hazari, A.
PDB entry 8t83: X-ray crystal structure of PfA-M1(M462K)
Classification: HYDROLASE
Source organism: Plasmodium falciparum
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2023-06-21
Authors: Yang, W., Drinkwater, N., Webb, C.T., McGowan, S.
PDB entry 8t84: Racemic mixture of amyloid beta segment 35-MVGGVV-40 forms heterochiral rippled beta-sheet, includes hexafluoroisopropanol
Classification: PROTEIN FIBRIL
Experimental method: X-RAY DIFFRACTION
Resolution: 1.101 Å
Deposited: 2023-06-21
Authors: Sawaya, M.R., Raskatov, J.A., Hazari, A.
PDB entry 8t85: Structure of RssB bound to beryllofluoride
Classification: SIGNALING PROTEIN
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.38 Å
Deposited: 2023-06-21
Authors: Brugger, C., Schwartz, J., Deaconescu, A.M.
PDB entry 8t86: Racemic mixture of amylin segment 25-AILSS-29 forms heterochiral rippled beta-sheet
Classification: PROTEIN FIBRIL
Experimental method: X-RAY DIFFRACTION
Resolution: 1.102 Å
Deposited: 2023-06-21
Authors: Sawaya, M.R., Raskatov, J.A., Hazari, A., Sajimon, M.
PDB entry 8t87: FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, unbound dimer crystal form 1
Classification: HYDROLASE
Source organism: Staphylococcus aureus USA300-0114
Experimental method: X-RAY DIFFRACTION
Resolution: 1.62 Å
Deposited: 2023-06-22
Authors: Fellner, M.
PDB entry 8t88: FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, Oxadiazolone JJ004 bound
Classification: HYDROLASE
Source organism: Staphylococcus aureus USA300-0114
Experimental method: X-RAY DIFFRACTION
Resolution: 1.54 Å
Deposited: 2023-06-22
Authors: Fellner, M.
PDB entry 8t89: Racemic mixture of amyloid beta segment 16-KLVFFA-21 forms heterochiral rippled beta-sheet
Classification: PROTEIN FIBRIL
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2023-06-22
Authors: Sawaya, M.R., Raskatov, J.A., Hazari, A.
PDB entry 8t8a: Structure of arginine oxidase from Pseudomonas sp. TRU 7192
Classification: OXIDOREDUCTASE
Source organism: Pseudomonas sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 3.4 Å
Deposited: 2023-06-22
Authors: Takahashi, K., Yamaguchi, H., Tatsumi, M., Sugiki, M.
PDB entry 8t8b: Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site formyl-MAI-tripeptidyl-tRNA analog ACCA-IAMf at 2.65A resolution
Classification: RIBOSOME/RNA
Source organism: Escherichia coli K-12; Thermus thermophilus HB8; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.65 Å
Deposited: 2023-06-22
Authors: Thaler, J., Syroegin, E.A., Breuker, K., Polikanov, Y.S., Micura, R.
PDB entry 8t8c: Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site formyl-MFI-tripeptidyl-tRNA analog ACCA-IFMf at 2.60A resolution
Classification: RIBOSOME
Source organism: Escherichia coli K-12; Thermus thermophilus HB8; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2023-06-22
Authors: Thaler, J., Syroegin, E.A., Breuker, K., Polikanov, Y.S., Micura, R.
PDB entry 8t8d: Structure of Helicobacter pylori adhesin A, HpaA
Classification: CELL ADHESION
Source organism: Helicobacter pylori
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2023-06-22
Authors: Martini, C., Calmettes, C.
PDB entry 8t8e: cryoEM structure of Smc5/6 5mer
Classification: DNA BINDING PROTEIN
Source organism: Saccharomyces cerevisiae W303
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.3 Å
Deposited: 2023-06-22
Authors: Yu, Y., Patel, D.J.
PDB entry 8t8f: Smc5/6 8mer
Classification: DNA BINDING PROTEIN
Source organism: Saccharomyces cerevisiae W303
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.8 Å
Deposited: 2023-06-22
Authors: Yu, Y., Patel, D.J.
PDB entry 8t8g: C208A Streptococcus pyogenes Sortase A (spySrtA) bound to LPALA peptide
Classification: HYDROLASE
Source organism: Streptococcus pyogenes; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2023-06-22
Authors: Kodama, H.M., Amacher, J.F.
PDB entry 8t8i: Structure of VHH-Fab complex with engineered Elbow FNQIKG, Crystal Kappa and SER substitutions
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.52 Å
Deposited: 2023-06-22
Authors: Filippova, E.V., Thompson, I., Kossiakoff, A.A.
PDB entry 8t8k: Structure of Domain of Unknown Function 507 (DUF507) in Space Group C222(1)
Classification: UNKNOWN FUNCTION
Source organism: Aquifex aeolicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.88 Å
Deposited: 2023-06-22
Authors: Tanner, J.J., McKay, C.E.
PDB entry 8t8l: Structure of Domain of Unknown Function 507 (DUF507) in Space Group P3(2)21
Classification: UNKNOWN FUNCTION
Source organism: Aquifex aeolicus
Experimental method: X-RAY DIFFRACTION, SOLUTION SCATTERING
Resolution: 1.9 Å
Deposited: 2023-06-22
Authors: Tanner, J.J., McKay, C.E.
PDB entry 8t8m: Quis-bound intermediate mGlu5
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens; Lama glama
Experimental method: ELECTRON MICROSCOPY
Resolution: 3 Å
Deposited: 2023-06-22
Authors: Krishna Kumar, K., Wang, H., Kobilka, B.K.
PDB entry 8t8n: Venezuelan Equine Encephalitis Virus (VEEV) Nonstructural Protein 2 (nsP2) Cysteine Protease Inhibited with CA074
Classification: VIRAL PROTEIN
Source organism: Venezuelan equine encephalitis virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.32 Å
Deposited: 2023-06-22
Authors: Compton, J.R., Legler, P.M.
PDB entry 8t8p: 33-mer FliF MS-ring from Salmonella
Classification: MOTOR PROTEIN
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.4 Å
Deposited: 2023-06-23
Authors: Singh, P.K., Iverson, T.M.
PDB entry 8t8q: Identification of GDC-1971 (RLY-1971), a SHP2 inhibitor designed for the treatment of solid tumors
Classification: HYDROLASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.27 Å
Deposited: 2023-06-23
Authors: Tang, Y., Nguyen, V., Wilbur, J.D.
PDB entry 8t8r: Sortilin-PGRN peptide complex
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.87 Å
Deposited: 2023-06-23
Authors: Srivastava, D.B., Srivastava, A., Cherf, G.M., Low, L.Y., Kannan, G.
PDB entry 8t8s: Sortilin-PGRN peptide complex
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.99 Å
Deposited: 2023-06-23
Authors: Srivastava, D.B., Srivastava, A., Cherf, G.M., Low, L.Y., Kannan, G.
PDB entry 8t8t: Crystal structure of TET25 in complex with PyDH2 ligand in P212121 space group
Classification: DNA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.62 Å
Deposited: 2023-06-23
Authors: Lam, G., Yatsunyk, L.A.
PDB entry 8t8u: Crystal structure of Terrestrivirus full-length Inositol pyrophosphate kinase in complex with ADP
Classification: VIRAL PROTEIN
Source organism: Terrestrivirus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2.01 Å
Deposited: 2023-06-23
Authors: Zong, G., Wang, H., Shears, S.B.
PDB entry 8t8v: Crystal structure of Terrestrivirus inositol pyrophosphate kinase in complex with ADP
Classification: VIRAL PROTEIN
Source organism: Terrestrivirus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 1.96 Å
Deposited: 2023-06-23
Authors: Zong, G., Wang, H., Shears, S.B.
PDB entry 8t8w: Crystal structure of Terrestrivirus Inositol pyrophosphatase kinase in complex with ATP
Classification: VIRAL PROTEIN
Source organism: Terrestrivirus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2023-06-23
Authors: Zong, G., Wang, H., Shears, S.B.
PDB entry 8t8x: Crystal structure of Terrestrivirus inositol pyrophosphate kinase in complex with AMP-PNP
Classification: VIRAL PROTEIN
Source organism: Terrestrivirus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2.59 Å
Deposited: 2023-06-23
Authors: Zong, G., Wang, H., Shears, S.B.
PDB entry 8t8y: Crystal structure of Terrestrivirus inositol pyrophosphate kinase in complex with ADP and 1,4,5-InsP3
Classification: VIRAL PROTEIN
Source organism: Terrestrivirus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2023-06-23
Authors: Zong, G., Wang, H., Shears, S.B.
PDB entry 8t8z: Crystal structure of Terrestrivirus Inositol pyrophosphatase kinase in complex with ADP and myo-(1OH)IP5
Classification: VIRAL PROTEIN
Source organism: Terrestrivirus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2023-06-23
Authors: Zong, G., Wang, H., Shears, S.B.
PDB entry 8t90: Crystal structure of Terrestrivirus Inositol pyrophosphatase kinase in complex with ADP and myo-(3OH)IP5
Classification: VIRAL PROTEIN
Source organism: Terrestrivirus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2023-06-23
Authors: Zong, G., Wang, H., Shears, S.B.
PDB entry 8t91: Crystal structure of Terrestrivirus Inositol pyrophosphatase kinase in complex with ADP and myo-IP6
Classification: VIRAL PROTEIN
Source organism: Terrestrivirus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2.56 Å
Deposited: 2023-06-23
Authors: Zong, G., Wang, H., Shears, S.B.
PDB entry 8t92: Crystal structure of Terrestrivirus Inositol pyrophosphatase kinase in complex with ADP and scyllo-D-(1,2,3,4)-IP4
Classification: VIRAL PROTEIN
Source organism: Terrestrivirus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2023-06-23
Authors: Zong, G., Wang, H., Shears, S.B.
PDB entry 8t93: Crystal structure of Terrestrivirus Inositol pyrophosphatase kinase in complex with ADP and scyllo-L-(1,2,3,4)-IP4
Classification: VIRAL PROTEIN
Source organism: Terrestrivirus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2023-06-23
Authors: Zong, G., Wang, H., Shears, S.B.
PDB entry 8t94: Influenza PAN endonuclease with 6-(4-(1H-tetrazol-5-yl)-2-(trifluoromethyl)phenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid
Classification: VIRAL PROTEIN,HYDROLASE/INHIBITOR
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.11 Å
Deposited: 2023-06-23
Authors: Kohlbrand, A.J., Cohen, S.M.
PDB entry 8t95: Crystal structure of Terrestrivirus Inositol pyrophosphatase kinase in complex with ADP and scyllo-(1,2,4,5)-IP4
Classification: VIRAL PROTEIN
Source organism: Terrestrivirus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2.61 Å
Deposited: 2023-06-23
Authors: Zong, G., Wang, H., Shears, S.B.
PDB entry 8t96: Crystal structure of Terrestrivirus Inositol pyrophosphatase kinase in complex with ADP and scyllo-IP5
Classification: VIRAL PROTEIN
Source organism: Terrestrivirus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2.36 Å
Deposited: 2023-06-23
Authors: Zong, G., Wang, H., Shears, S.B.
PDB entry 8t97: Crystal structure of Terrestrivirus Inositol pyrophosphatase kinase in complex with ADP and scyllo-IP6
Classification: VIRAL PROTEIN
Source organism: Terrestrivirus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2.46 Å
Deposited: 2023-06-23
Authors: Zong, G., Wang, H., Shears, S.B.
PDB entry 8t98: Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with Scyllo-3-PP-(1,2,4,5)IP4, Mg, and Fluoride ion
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.3 Å
Deposited: 2023-06-23
Authors: Zong, G., Wang, H., Shears, S.B.
PDB entry 8t99: Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with Scyllo-L-1,4-[PP]2-(2,3)IP2, Mg, and Fluoride ion
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2023-06-23
Authors: Zong, G., Wang, H., Shears, S.B.
PDB entry 8t9a: CryoEM structure of human DDB1-DCAF12 in complex with MAGEA3
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.17 Å
Deposited: 2023-06-23
Authors: Duda, D., Righetto, G., Li, Y., Loppnau, P., Seitova, A., Santhakumar, V., Halabelian, L., Yin, Y.
PDB entry 8t9b: Structure of the CK variant of Fab F1 (FabC-F1) in complex with the C-terminal FN3 domain of EphA2
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 4.2 Å
Deposited: 2023-06-23
Authors: Singer, A.U., Bruce, H.A., Enderle, L., Blazer, L., Adams, J.J., Sicheri, F., Sidhu, S.S.
PDB entry 8t9c: Zophobas morio black wasting virus strain UT-morio virion structure
Classification: VIRUS/DNA
Source organism: Zophobas morio
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.7 Å
Deposited: 2023-06-23
Authors: Penzes, J.J., Kaelber, J.T.
PDB entry 8t9d: CryoEM structure of TR-TRAP
Classification: STRUCTURAL PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.66 Å
Deposited: 2023-06-23
Authors: Zhao, H., Asturias, F.
PDB entry 8t9e: Zophobas morio black wasting virus strain UT-morio empty capsid structure
Classification: VIRUS
Source organism: Zophobas morio
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.9 Å
Deposited: 2023-06-23
Authors: Penzes, J.J., Kaelber, J.T.
PDB entry 8t9f: Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1
Classification: GENE REGULATION
Source organism: Escherichia coli 'BL21-Gold(DE3)pLysS AG'; Homo sapiens; Xenopus laevis
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.6 Å
Deposited: 2023-06-23
Authors: Abini-Agbomson, S., Armache, K.-J.
PDB entry 8t9g: Automethylated PRC2 dimer bound to nucleosome
Classification: GENE REGULATION
Source organism: Homo sapiens; Xenopus laevis; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 6.2 Å
Deposited: 2023-06-23
Authors: Sauer, P.V., Pavlenko, E., Nogales, E., Poepsel, S.
PDB entry 8t9h: Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1
Classification: GENE REGULATION
Source organism: Escherichia coli 'BL21-Gold(DE3)pLysS AG'; Homo sapiens; Xenopus laevis
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.37 Å
Deposited: 2023-06-24
Authors: Abini-Agbomson, S., Armache, K.-J.
PDB entry 8t9l: Pom34-Pom152 membrane attachment site yeast NPC
Classification: TRANSPORT PROTEIN
Source organism: Saccharomyces cerevisiae
Experimental method: ELECTRON MICROSCOPY
Resolution: 7 Å
Deposited: 2023-06-24
Authors: Akey, C.W., Echeverria, I., Ouch, C., Fernandez-Martinez, J., Rout, M.P.
PDB entry 8t9n: Bacillus subtilis RsgI GGG mutant
Classification: MEMBRANE PROTEIN
Source organism: Bacillus subtilis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2023-06-24
Authors: Brogan, A.P., Habib, C., Hobbs, S.J., Kranzusch, P.J., Rudner, D.Z.
PDB entry 8t9o: Crystal structure of CF, a heterohexamer of the 4-oxalocrotonate tautomerase (4-OT) family
Classification: ISOMERASE
Source organism: Herbaspirillum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2023-06-24
Authors: Moreno, R.Y., Zhang, Y.J.
PDB entry 8t9p: Crystal Structure of YR, a heterohexamer of the 4-oxalocrotonate tautomerase (4-OT) family
Classification: ISOMERASE
Source organism: Herbaspirillum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.04 Å
Deposited: 2023-06-24
Authors: Moreno, R.Y., Zhang, Y.J.
PDB entry 8t9q: Crystal structure of fused YR, an asymmetric 4-OT trimer
Classification: ISOMERASE
Source organism: Herbaspirillum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.29 Å
Deposited: 2023-06-24
Authors: Moreno, R.Y., Zhang, Y.J.
PDB entry 8t9r: T4 highly immunogenic outer capsid protein C-terminal domain bound to a vertex-proximal gp23* capsomer of the prolate capsid in two preferred orientations.
Classification: VIRAL PROTEIN
Source organism: Escherichia phage T4
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.4 Å
Deposited: 2023-06-24
Authors: Fokine, A., Rao, V.B.
PDB entry 8t9s: Structure of gp82 from mycobacteriophage Phaedrus
Classification: VIRAL PROTEIN
Source organism: Mycobacterium phage Phaedrus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.21 Å
Deposited: 2023-06-24
Authors: Binsabaan, S.A., VanDemark, A.P.
PDB entry 8t9t: Apo Crystal Structure of a Substrate Binding Protein (IseP) from an Isethionate TRAP Transporter
Classification: TRANSPORT PROTEIN
Source organism: Oleidesulfovibrio alaskensis G20
Experimental method: X-RAY DIFFRACTION
Resolution: 1.48 Å
Deposited: 2023-06-25
Authors: Newton-Vesty, M.C., Dobson, R.C.J.
PDB entry 8t9u: Human PU.1 ETS-domain (165-270) in complex with d(AATAAGCGIAAGTGGG)
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.47 Å
Deposited: 2023-06-26
Authors: Terrell, J.R., Poon, G.M.K.
PDB entry 8t9v: RTA-RUNT-59 complex structure
Classification: TOXIN
Source organism: Ricinus communis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.945 Å
Deposited: 2023-06-26
Authors: Rudolph, M.J., Tumer, N.
PDB entry 8t9w: Crystal structure of a GH140 apiosidase derived from a lignocellulolytic enriched mangrove metagenome.
Classification: HYDROLASE
Source organism: metagenome
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2023-06-26
Authors: Liberato, M.V., Squina, F.
PDB entry 8t9x: Zophobas morio black wasting virus strain NJ2-molitor virion structure
Classification: VIRUS/DNA
Source organism: Zophobas morio black wasting virus
Experimental method: ELECTRON MICROSCOPY
Resolution: 2 Å
Deposited: 2023-06-26
Authors: Penzes, J.J., Kaelber, J.T.
PDB entry 8t9y: Structure of VHH-Fab complex with engineered Elbow FNQIKG and Crystal Kappa regions
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.52 Å
Deposited: 2023-06-26
Authors: Filippova, E.V., Thompson, I., Kossiakoff, A.A.
PDB entry 8t9z: Structural of M8C10 Fab in complex human metapneumovirus fusion protein
Classification: VIRAL PROTEIN/Immune System
Source organism: Homo sapiens; Human metapneumovirus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.995 Å
Deposited: 2023-06-26
Authors: Su, H.P., Eddins, M.J., Shipman, J.M., Kostas, J., Reid, J.C.
PDB entry 8ta0: Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM881
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Mycobacterium ulcerans
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2023-06-26
Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 8ta1: Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM907
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Mycobacterium ulcerans
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2023-06-26
Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 8ta2: Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with bound inhibitor AK-42
Classification: TRANSPORT PROTEIN/INHIBITOR
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.74 Å
Deposited: 2023-06-26
Authors: Xu, M., Neelands, T., Powers, A.S., Liu, Y., Miller, S., Pintilie, G., Du Bois, J., Dror, R.O., Chiu, W., Maduke, M.