LiteFold/PDB huggingface dataset:
PDB entry 4zpe: BACE1 in complex with 4-(cyclohexylamino)-1-(3-fluorophenyl)-8-(3-isopropoxybenzyl)-1,3,8-triazaspiro[4.5]dec-3-en-2-one
Classification: Hydrolase/hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2015-05-07
Authors: Orth, P.
PDB entry 4zpf: BACE1 in complex with 8-(3-((1-aminopropan-2-yl)oxy)benzyl)-4-(cyclohexylamino)-1-(3-fluorophenyl)-1,3,8-triazaspiro[4.5]dec-3-en-2-one
Classification: Hydrolase/Hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2015-05-07
Authors: Orth, P.
PDB entry 4zpg: BACE1 in complex with 8-benzyl-4-(cyclohexylamino)-1-(3-fluorophenyl)-7-methyl-1,3,8-triazaspiro[4.5]dec-3-en-2-one
Classification: Hydrolase/hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-05-07
Authors: Orth, P.
PDB entry 4zph: Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with Proflavine
Classification: PROTEIN TRANSPORT/TRANSCRIPTION
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2015-05-07
Authors: Wu, D., Potluri, N., Lu, J., Kim, Y., Rastinejad, F.
PDB entry 4zpi: Crystal Structure of HygX from Streptomyces hygroscopicus with iron bound
Classification: OXIDOREDUCTASE
Source organism: Streptomyces hygroscopicus subsp. hygroscopicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.504 Å
Deposited: 2015-05-07
Authors: McCulloch, K.M., McCranie, E.K., Sarwar, M., Mathieu, J.L., Gitschlag, B.L., Du, Y., Bachmann, B.O., Iverson, T.M.
PDB entry 4zpj: ABC transporter substrate-binding protein from Sphaerobacter thermophilus
Classification: TRANSPORT PROTEIN
Source organism: Sphaerobacter thermophilus (strain DSM 20745 / S 6022)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.24 Å
Deposited: 2015-05-07
Authors: OSIPIUK, J., Holowicki, J., Clancy, S., JOACHIMIAK, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 4zpk: Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with HRE DNA
Classification: PROTEIN TRANSPORT/TRANSCRIPTION/DNA
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.6 Å
Deposited: 2015-05-08
Authors: Wu, D., Potluri, N., Lu, J., Kim, Y., Rastinejad, F.
PDB entry 4zpl: Crystal Structure of Protocadherin Beta 1 EC1-3
Classification: CELL ADHESION
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.3 Å
Deposited: 2015-05-08
Authors: Goodman, K.M., Bahna, F., Shapiro, L.
PDB entry 4zpm: Crystal Structure of Protocadherin Alpha C2 EC1-3
Classification: CELL ADHESION
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2015-05-08
Authors: Goodman, K.M., Mannepalli, S., Shapiro, L.
PDB entry 4zpn: Crystal Structure of Protocadherin Gamma C5 EC1-3 with extended N-terminus
Classification: CELL ADHESION
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.3 Å
Deposited: 2015-05-08
Authors: Goodman, K.M., Wolcott, H.N., Bahna, F., Shapiro, L.
PDB entry 4zpo: Crystal Structure of Protocadherin Gamma C5 EC1-3
Classification: CELL ADHESION
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2015-05-08
Authors: Wolcott, H.N., Goodman, K.M., Bahna, F., Mannepalli, S., Rubinstein, R., Honig, B., Shapiro, L.
PDB entry 4zpp: Crystal Structure of Protocadherin Gamma C5 EC1-3
Classification: CELL ADHESION
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.002 Å
Deposited: 2015-05-08
Authors: Wolcott, H.N., Goodman, K.M., Bahna, F., Mannepalli, S., Shapiro, L.
PDB entry 4zpq: Crystal Structure of Protocadherin Gamma C5 EC1-3
Classification: CELL ADHESION
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.099 Å
Deposited: 2015-05-08
Authors: Wolcott, H.N., Goodman, K.M., Bahna, F., Mannepalli, S., Shapiro, L.
PDB entry 4zpr: Crystal Structure of the Heterodimeric HIF-1a:ARNT Complex with HRE DNA
Classification: PROTEIN TRANSPORT/TRANSCRIPTION/DNA
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.902 Å
Deposited: 2015-05-08
Authors: Wu, D., Potluri, N., Lu, J., Kim, Y., Rastinejad, F.
PDB entry 4zps: Crystal Structure of Protocadherin Gamma A8 EC1-3
Classification: CELL ADHESION
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2015-05-08
Authors: Goodman, K.M., Mannepalli, S., Shapiro, L.
PDB entry 4zpt: Structure of MERS-Coronavirus Spike Receptor-binding Domain (England1 Strain) in Complex with Vaccine-Elicited Murine Neutralizing Antibody D12 (Crystal Form 1)
Classification: Viral protein/Immune system
Source organism: Human coronavirus EMC (isolate United Kingdom/H123990006/2012); Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.591 Å
Deposited: 2015-05-08
Authors: Joyce, M.G., Mascola, J.R., Graham, B.S., Kwong, P.D.
PDB entry 4zpu: The structure of DLP12 endolysin exhibits likely active and inactive conformations.
Classification: HYDROLASE
Source organism: Escherichia coli (strain K12)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2015-05-08
Authors: Kesavan, B., Arockiasamy, A., Krishnaswamy, S.
PDB entry 4zpv: Structure of MERS-Coronavirus Spike Receptor-binding Domain (England1 Strain) in Complex with Vaccine-Elicited Murine Neutralizing Antibody D12 (Crystal Form 2)
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Human coronavirus EMC (isolate United Kingdom/H123990006/2012); Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2 Å
Deposited: 2015-05-08
Authors: Joyce, M.G., Mascola, J.R., Graham, B.S., Kwong, P.D.
PDB entry 4zpw: Structure of unbound MERS-CoV spike receptor-binding domain (England1 strain).
Classification: VIRAL PROTEIN
Source organism: Human coronavirus EMC (isolate United Kingdom/H123990006/2012)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.023 Å
Deposited: 2015-05-08
Authors: Joyce, M.G., Mascola, J.R., Graham, B.S., Kwong, P.D.
PDB entry 4zpx: Crystal structure of Lon ATPase domain from Thermococcus onnurineus NA1
Classification: HYDROLASE
Source organism: Thermococcus onnurineus (strain NA1)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.03 Å
Deposited: 2015-05-08
Authors: An, Y.J., Kim, M.I., Na, J.H., Cha, S.S.
PDB entry 4zpy: Structure of N170A MVM mutant empty capsid
Classification: VIRUS
Source organism: Murine minute virus strain MVM prototype
Experimental method: X-RAY DIFFRACTION
Resolution: 3.8 Å
Deposited: 2015-05-08
Authors: Guerra, P., Querol-Audi, J., Silva, C., Mateu, M.G., Verdaguer, N.
PDB entry 4zpz: Crystal Structure of Semi-synthetic Ubiquitin with Phospho-Ser65 and Ala46Cys
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.54 Å
Deposited: 2015-05-08
Authors: Han, C., Virdee, S.
PDB entry 4zq0: crystal structure of Giardia 14-3-3 in complex with the phosphopeptide A8Ap
Classification: SIGNALING PROTEIN
Source organism: Giardia lamblia P15; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1 Å
Deposited: 2015-05-08
Authors: Fiorillo, A., Ilari, A.
PDB entry 4zq3: Crystal structure of Staphylococcal nuclease variant Delta+PHS I92T at cryogenic temperature
Classification: HYDROLASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2015-05-08
Authors: Sorenson, J.L., Schlessman, J.L., Garcia-Moreno E., B.
PDB entry 4zq8: Crystal structure of a terpene synthase from Streptomyces lydicus, target EFI-540129
Classification: TRANSFERASE
Source organism: Streptomyces lydicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-05-08
Authors: Toro, R., Bhosle, R., Vetting, M.W., Al Obaidi, N.F., Morisco, L.L., Wasserman, S.R., Sojitra, S., Stead, M., Washington, E., Scott Glenn, A., Chowdhury, S., Evans, B., Hillerich, B., Love, J., Seidel, R.D., Whalen, K.L., Gerlt, J.A., Poulter, C.D., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4zq9: X-ray structure of AAV-2 OBD bound to AAVS1 site 3:1
Classification: DNA BINDING PROTEIN/DNA
Source organism: Adeno-associated virus 2 (isolate Srivastava/1982); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-05-08
Authors: Musayev, F.N., Zarate-Perez, F., Escalante, C.R.
PDB entry 4zqa: Crystal Structure of the Sds3 Dimerization Domain
Classification: TRANSCRIPTION REPRESSOR
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2015-05-08
Authors: Chan, C.W., Mondragon, A., Clark, M., Radhakrishnan, I.
PDB entry 4zqb: Crystal structure of NADP-dependent dehydrogenase from Rhodobactersphaeroides in complex with NADP and sulfate
Classification: OXIDOREDUCTASE
Source organism: Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2015-05-08
Authors: Kowiel, M., Gasiorowska, O.A., Shabalin, I.G., Handing, K.B., Porebski, P.J., Bonanno, J., Almo, S.C., Minor, W., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4zqc: Tryptophan Synthase from Salmonella typhimurium in complex with two molecules of N-(4'-trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6F) inhibitor in the alpha-site and a single F6F molecule in the beta-site at 1.54 Angstrom resolution.
Classification: LYASE/LYASE INHIBITOR
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Experimental method: X-RAY DIFFRACTION
Resolution: 1.54 Å
Deposited: 2015-05-08
Authors: Hilario, E., Caulkins, B.G., Young, R.P., Dunn, M.F., Mueller, L.J., Fan, L.
PDB entry 4zqd: Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with the Benzoxadiazole Antagonist 0X3
Classification: PROTEIN TRANSPORT/TRANSCRIPTION
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.87 Å
Deposited: 2015-05-09
Authors: Wu, D., Potluri, N., Lu, J., Kim, Y., Rastinejad, F.
PDB entry 4zqe: Crystal structure of DOX-P Reductoisomerase in complex with magnesium
Classification: OXIDOREDUCTASE
Source organism: Moraxella catarrhalis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2015-05-10
Authors: Birkinshaw, R.W., Brady, R.L.
PDB entry 4zqf: Crystal structure of DOX-P Reductoisomerase fosmidomycin and magnesium
Classification: OXIDOREDUCTASE
Source organism: Moraxella catarrhalis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2015-05-10
Authors: Birkinshaw, R.W., Brady, R.L.
PDB entry 4zqg: Crystal structure of the Moraxella catarrhalis DOX-P Reductoisomerase in complex with NADH, fosmidomycin and magnesium
Classification: OXIDOREDUCTASE
Source organism: Moraxella catarrhalis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2015-05-10
Authors: Birkinshaw, R.W., Brady, R.L.
PDB entry 4zqh: Crystal structure of DOX-P Reductoisomerase in complex with NADPH, fosmidomycin and magnesium
Classification: OXIDOREDUCTASE
Source organism: Moraxella catarrhalis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2015-05-10
Authors: Birkinshaw, R.W., Brady, R.L.
PDB entry 4zqi: Crystal structure of Apo D-alanine-D-alanine ligase(DDL) from Yersinia pestis
Classification: LIGASE
Source organism: Yersinia pestis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2015-05-10
Authors: Tran, H.-T., Kang, L.-W., Hong, M.-K., Ngo, H.P.T., Huynh, K.H., Ahn, Y.J.
PDB entry 4zqk: Structure of the complex of human programmed death-1 (PD-1) and its ligand PD-L1.
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.45 Å
Deposited: 2015-05-10
Authors: Zak, K.M., Dubin, G., Holak, T.A.
PDB entry 4zql: Crystal structure of TRIM24 with 3,4-dimethoxy-N-(6-(4-methoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)benzenesulfonamide inhibitor
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.79 Å
Deposited: 2015-05-10
Authors: Tallant, C., Structural Genomics Consortium (SGC), Clark, P.G.K., Vieira, L.C.C., Krojer, T., Nunez-Alonso, G., Picaud, S., Fedorov, O., Dixon, D.J., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Brennan, P.E., Knapp, S.
PDB entry 4zqm: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with XMP and NAD
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.602 Å
Deposited: 2015-05-10
Authors: Kim, Y., Maltseva, N., Makowska-Grzyska, M., Gu, M., Kavitha, M., Hedstrom, L., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4zqn: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with IMP and the inhibitor P41
Classification: Oxidoreductase/Oxidoreductase inhibitor
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-05-10
Authors: Kim, Y., Makowska-Grzyska, M., Gu, M., Kavitha, M., Hedstrom, L., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4zqo: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with IMP and the inhibitor Q67
Classification: Oxidoreductase/Oxidoreductase inhibitor
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.76 Å
Deposited: 2015-05-10
Authors: Kim, Y., Makowska-Grzyska, M., Gu, M., Kavitha, M., Hedstrom, L., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4zqp: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with IMP and the inhibitor MAD1
Classification: Oxidoreductase/Oxidoreductase inhibitor
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2015-05-10
Authors: Kim, Y., Makowska-Grzyska, M., Gu, M., Kavitha, M., Hedstrom, L., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4zqq: Apo form of influenza strain H1N1 polymerase acidic subunit N-terminal region
Classification: HYDROLASE
Source organism: Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2015-05-11
Authors: Fudo, S., Yamamoto, N., Nukaga, M., Odagiri, T., Tashiro, M., Neya, S., Hoshino, T.
PDB entry 4zqr: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.692 Å
Deposited: 2015-05-11
Authors: Kim, Y., Makowska-Grzyska, M., Gu, M., Kavitha, M., Hedstrom, L., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4zqs: New compact conformation of linear Ub2 structure
Classification: PROTEIN BINDING
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.804 Å
Deposited: 2015-05-11
Authors: Thach, T.T., Shin, D., Han, S., Lee, S.
PDB entry 4zqt: Crystal structure of PfA-M1 with virtual ligand inhibitor
Classification: HYDROLASE/HYDROLASE inhibitor
Source organism: Plasmodium falciparum 3D7
Experimental method: X-RAY DIFFRACTION
Resolution: 1.981 Å
Deposited: 2015-05-11
Authors: Ruggeri, C., Drinkwater, N., McGowan, S.
PDB entry 4zqu: CdiA-CT/CdiI toxin and immunity complex from Yersinia pseudotuberculosis
Classification: TOXIN
Source organism: Salmonella enterica subsp. enterica serovar Rubislaw str. ATCC 10717; Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.09 Å
Deposited: 2015-05-11
Authors: Morse, R.P., Johnson, P.M., Credali, A., Goulding, C.W.
PDB entry 4zqv: CdiI Immunity protein from Yersinia kristensenii
Classification: IMMUNE SYSTEM
Source organism: Yersinia kristensenii ATCC 33638
Experimental method: X-RAY DIFFRACTION
Resolution: 1.803 Å
Deposited: 2015-05-11
Authors: Morse, R.P., Goulding, C.W.
PDB entry 4zqw: CdiI from Escherichia coli EC869 in complex with a macrocyclic peptide
Classification: toxin/inhibitor
Source organism: Escherichia coli O157:H7 (strain EC869); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.001 Å
Deposited: 2015-05-11
Authors: Morse, R.P., Goulding, C.W.
PDB entry 4zqx: A revised partiality model and post-refinement algorithm for X-ray free-electron laser data
Classification: VIRAL PROTEIN
Source organism: Uranotaenia sapphirina cypovirus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.46 Å
Deposited: 2015-05-11
Authors: Ginn, H.M., Brewster, A.S., Hattne, J., Evans, G., Wagner, A., Grimes, J., Sauter, N.K., Sutton, G., Stuart, D.I.
PDB entry 4zqy: Ringhalexin from hemachatus haemachatus: A novel inhibitor of extrinsic tenase complex
Classification: TOXIN
Source organism: Hemachatus haemachatus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9515 Å
Deposited: 2015-05-11
Authors: Jobichen, C., Sivaraman, J.
PDB entry 4zr0: Full length scs7p (only hydroxylase domain visible)
Classification: OXIDOREDUCTASE
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.8 Å
Deposited: 2015-05-11
Authors: Zhu, G., Koszelak-Rosenblum, M., Malkowski, M.G., Membrane Protein Structural Biology Consortium (MPSBC)
PDB entry 4zr1: Hydroxylase domain of scs7p
Classification: OXIDOREDUCTASE
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6008 Å
Deposited: 2015-05-11
Authors: Zhu, G., Koszelak-Rosenblum, M., Malkowski, M.G., Membrane Protein Structural Biology Consortium (MPSBC)
PDB entry 4zr2: Crystal Structure of the Domain-Swapped Dimer K40L:Q108K:Y60W mutant of Human Cellular Retinol Binding Protein II
Classification: LIPID BINDING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8024 Å
Deposited: 2015-05-11
Authors: Assar, Z., Nossoni, Z., Geiger, J.H.
PDB entry 4zr5: Soluble rabbit neprilysin in complex with phosphoramidon
Classification: HYDROLASE
Source organism: Oryctolagus cuniculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8016 Å
Deposited: 2015-05-11
Authors: Labiuk, S.L., Grochulski, P., Sygusch, J.
PDB entry 4zr6: Lymnaea Stagnalis Acetylcholine Binding Protein in Complex with 3-[(4E)-4-[(3-methylimidazol-4-yl)methylene]-2,3-dihydropyrrol-5-yl]pyridine
Classification: ACETYLCHOLINE BINDING PROTEIN
Source organism: Lymnaea stagnalis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-05-11
Authors: Bobango, J., Bryant, D., Denton, T.T., Talley, T.T.
PDB entry 4zr7: The structure of a domain of a functionally unknown protein from Bacillus subtilis subsp. subtilis str. 168
Classification: TRANSFERASE
Source organism: Bacillus subtilis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.86 Å
Deposited: 2015-05-11
Authors: Tan, K., Li, H., Jedrzejczak, R., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 4zr8: Structure of uroporphyrinogen decarboxylase from Acinetobacter baumannii
Classification: LYASE
Source organism: Acinetobacter baumannii AB5075
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2015-05-11
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 4zra: CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS LPRG BINDING TO TRIACYLGLYCERIDE
Classification: LIPID BINDING PROTEIN
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.83 Å
Deposited: 2015-05-12
Authors: Martinot, A.J., Farrow, M., Bai, L., Layre, E., Cheng, T.Y., Tsai, J.H.C., Iqbal, J., Annand, J., Sullivan, Z., Hussain, M., Sacchettini, J., Moody, D.B., Seeliger, J., Rubin, E.J., TB Structural Genomics Consortium (TBSGC)
PDB entry 4zrb: Crystal Structure of Hypothetical Thioesterase Protein SP_1851 with Coenzyme A from Streptococcus pneumoniae TIGR4
Classification: HYDROLASE
Source organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2015-05-12
Authors: Khandokar, Y.B., Srivastava, P., Forwood, J.K.
PDB entry 4zrc: Crystal structure of MSM-13, a putative T1-like thiolase from Mycobacterium smegmatis
Classification: TRANSFERASE
Source organism: Mycobacterium smegmatis str. MC2 155
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2015-05-12
Authors: Janardan, N., Harijan, R.K., Keima, T.R., Wierenga, R., Murthy, M.R.N.
PDB entry 4zrd: Crystal structure of SMG1 F278N mutant
Classification: HYDROLASE
Source organism: Malassezia globosa (strain ATCC MYA-4612 / CBS 7966)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2015-05-12
Authors: Xu, J., Xu, H., Hou, S., Liu, J.
PDB entry 4zre: Crystal structure of SMG1 F278D mutant
Classification: HYDROLASE
Source organism: Malassezia globosa
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-05-12
Authors: Xu, J., Xu, H., Hou, S., Liu, J.
PDB entry 4zrf: Crystal Structure of Hypothetical Thioesterase Protein SP_1851 from Streptococcus pneumoniae TIGR4
Classification: HYDROLASE
Source organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.86 Å
Deposited: 2015-05-12
Authors: Khandokar, Y.B., Srivastava, P., Forwood, J.K.
PDB entry 4zrg: Visual arrestin mutant - R175E
Classification: SIGNALING PROTEIN
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2015-05-12
Authors: Granzin, J., Stadler, A., Cousin, A., Schlesinger, R., Batra-Safferling, R.
PDB entry 4zri: Crystal structure of Merlin-FERM and Lats2
Classification: SIGNALING PROTEIN/TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2015-05-12
Authors: Li, F., Zhou, H., Long, J., Shen, Y.
PDB entry 4zrj: Structure of Merlin-FERM and CTD
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2015-05-12
Authors: Lin, Z., Li, F., Long, J., Shen, Y.
PDB entry 4zrk: Merlin-FERM and Lats1 complex
Classification: SIGNALING PROTEIN/TRANSFERASE
Source organism: Homo sapiens; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.316 Å
Deposited: 2015-05-12
Authors: Lin, Z., Li, Y., Wei, Z., Zhang, M.
PDB entry 4zrl: Structure of the non canonical Poly(A) polymerase complex GLD-2 - GLD-3
Classification: TRANSFERASE
Source organism: Caenorhabditis elegans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.28 Å
Deposited: 2015-05-12
Authors: Nakel, K., Bonneau, F., Eckmann, C.R., Conti, E.
PDB entry 4zrm: Crystal Structure of UDP-Glucose 4-Epimerase (TM0509) from Hyperthermophilic Eubacterium Thermotoga maritima
Classification: ISOMERASE
Source organism: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2015-05-12
Authors: Choi, J.M., Lee, D.W., Lee, S.H.
PDB entry 4zrn: Crystal Structure of UDP-Glucose 4-Epimerase (TM0509) with UDP-glucose from Hyperthermophilic Eubacterium Thermotoga Maritima
Classification: ISOMERASE
Source organism: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-05-12
Authors: Choi, J.M., Lee, D.W., Lee, S.H.
PDB entry 4zro: 2.1 A X-Ray Structure of FIPV-3CLpro bound to covalent inhibitor
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Feline coronavirus (strain FIPV WSU-79/1146); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.0566 Å
Deposited: 2015-05-12
Authors: St John, S.E., Mesecar, A.D.
PDB entry 4zrp: TC:CD320
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2015-05-12
Authors: Alam, A., Locher, K.P.
PDB entry 4zrq: E88 deletion mutant of CD320 in complex with TC2
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-05-12
Authors: Alam, A., Locher, K.P.
PDB entry 4zrr: Crystal Structure of Monomeric Bacteriophytochrome mutant D207L Y263F at 1.5 A resolution Using a home source.
Classification: TRANSFERASE
Source organism: Deinococcus radiodurans
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2015-05-12
Authors: Bhattacharya, S., Satyshur, K.A., Lehtivuori, H., Forest, K.T.
PDB entry 4zrs: Crystal structure of a cloned feruloyl esterase from a soil metagenomic library
Classification: HYDROLASE
Source organism: uncultured bacterium
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-05-12
Authors: Xie, W., Chen, R., Cao, L., Liu, Y.
PDB entry 4zrt: PTP1BC215S bound to Nephrin peptide substrate
Classification: HYDROLASE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.74 Å
Deposited: 2015-05-12
Authors: Selner, N.G., Bell, C.E., Pei, D.
PDB entry 4zru: X-ray crystal structure of Lymnaea stagnalis acetylcholine binding protein (Ls-AChBP) in complex with 3-[2-[(2S)-pyrrolidin-2-yl]ethynyl]pyridine (TI-5180)
Classification: ACETYLCHOLINE BINDING PROTEIN
Source organism: Lymnaea stagnalis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2015-05-12
Authors: Bobango, J., Sankaran, B., Park, J.F., Wu, J., Talley, T.T.
PDB entry 4zrv: Structure of cow mincle CRD complexed with trehalose mono butyrate
Classification: SUGAR BINDING PROTEIN
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.095 Å
Deposited: 2015-05-12
Authors: Feinberg, H., Rambaruth, N.D.S., Taylor, M.E., Drickamer, K., Weis, W.I.
PDB entry 4zrw: Structure of cow mincle complexed with trehalose
Classification: SUGAR BINDING PROTEIN
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-05-12
Authors: Feinberg, H., Rambaruth, N.D.S., Taylor, M.E., Drickamer, K., Weis, W.I.
PDB entry 4zrx: Crystal structure of a putative alpha-L-fucosidase (BACOVA_04357) from Bacteroides ovatus ATCC 8483 at 1.59 A resolution
Classification: HYDROLASE
Source organism: Bacteroides ovatus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.59 Å
Deposited: 2015-05-12
Authors: Joint Center for Structural Genomics (JCSG)
PDB entry 4zry: Crystal structure of the heterocomplex between coil 2B domains of human intermediate filament proteins keratin 1 (KRT1) and keratin 10 (KRT10)
Classification: PROTEIN FIBRIL
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.30013 Å
Deposited: 2015-05-12
Authors: Bunick, C.G., Steitz, T.A.
PDB entry 4zrz: PlyCB mutant R66E
Classification: Antimicrobial protein, Viral protein
Source organism: Streptococcus phage C1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.72 Å
Deposited: 2015-05-12
Authors: Gallagher, D.T., Nelson, D.C., Shen, Y.
PDB entry 4zs0: Human Aurora A catalytic domain bound to SB-6-OH
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2015-05-12
Authors: Marcaida, M.J., Kilchmann, F., Schick, T., Reymond, J.L.
PDB entry 4zs2: Structural complex of FTO/fluorescein
Classification: FLUORESCENT PROTEIN/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.16 Å
Deposited: 2015-05-13
Authors: Wang, T., Hong, T., Huang, Y., Yang, C.G., Zhou, X.
PDB entry 4zs3: Structural complex of 5-aminofluorescein bound to the FTO protein
Classification: FLUORESCENT PROTEIN/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.45 Å
Deposited: 2015-05-13
Authors: Wang, T., Hong, T., Huang, Y., Yang, C.G., Zhou, X.
PDB entry 4zs4: Crystal Structure of the Inactive Alpha-kinase Domain of Myosin-II Heavy Chain Kinase A (D756A) Complexed with ATP
Classification: TRANSFERASE
Source organism: Dictyostelium discoideum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2015-05-13
Authors: Ye, Q., Jia, Z.
PDB entry 4zs6: Receptor binding domain and Fab complex
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Middle East respiratory syndrome coronavirus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.166 Å
Deposited: 2015-05-13
Authors: Yu, X., Wang, X.
PDB entry 4zs7: Structural mimicry of receptor interaction by antagonistic IL-6 antibodies
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Lama glama
Experimental method: X-RAY DIFFRACTION
Resolution: 2.93 Å
Deposited: 2015-05-13
Authors: Blanchetot, C., De Jonge, N., Desmyter, A., Ongenae, N., Hofman, E., Klarenbeek, A., Sadi, A., Hultberg, A., Kretz-Rommel, A., Spinelli, S., Loris, R., Cambillau, C., de Haard, H.
PDB entry 4zs8: Crystal structure of ligand-free, full length DasR
Classification: TRANSCRIPTION
Source organism: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-05-13
Authors: Fillenberg, S.B., Muller, Y.A.
PDB entry 4zs9: Raffinose and panose binding protein from Bifidobacterium animalis subsp. lactis Bl-04, bound with raffinose
Classification: TRANSPORT PROTEIN
Source organism: Bifidobacterium animalis subsp. lactis Bl-04
Experimental method: X-RAY DIFFRACTION
Resolution: 1.37 Å
Deposited: 2015-05-13
Authors: Fredslund, F., Ejby, M., Andersen, J.M., Slotboom, D.J., Abou Hachem, M.
PDB entry 4zsa: Crystal structure of FGFR1 kinase domain in complex with 7n
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-05-13
Authors: Liu, Q.F., Xu, Y.C.
PDB entry 4zsb: Crystal structure of the ligand-free effector-binding domain of DasR (DasR-EBD)
Classification: TRANSCRIPTION
Source organism: Streptomyces coelicolor A3(2)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.004 Å
Deposited: 2015-05-13
Authors: Fillenberg, S.B., Grau, F.C., Muller, Y.A.
PDB entry 4zsc: Human Cyclophilin D Complexed with an Inhibitor at room temperature
Classification: ISOMERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2015-05-13
Authors: Gelin, M., Delfosse, V., Allemand, F., Hoh, F., Sallaz-Damaz, Y., Pirocchi, M., Bourguet, W., Ferrer, J.-L., Labesse, G., Guichou, J.-F.
PDB entry 4zsd: Human Cyclophilin D Complexed with an Inhibitor at room temperature
Classification: ISOMERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2015-05-13
Authors: Gelin, M., Delfosse, V., Allemand, F., Hoh, F., Sallaz-Damaz, Y., Pirocchi, M., Bourguet, W., Ferrer, J.-L., Labesse, G., Guichou, J.-F.
PDB entry 4zse: Crystal structure of EGFR 696-1022 T790M/V948R, crystal form II
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.97 Å
Deposited: 2015-05-13
Authors: Yan, X.E., Yun, C.H.
PDB entry 4zsf: Crystal structure of pre-specific restriction endonuclease BsaWI-DNA complex
Classification: PROTEIN/DNA
Source organism: Geobacillus stearothermophilus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2015-05-13
Authors: Tamulaitiene, G., Rutkauskas, M., Grazulis, S., Siksnys, V.
PDB entry 4zsg: MITOGEN ACTIVATED PROTEIN KINASE 7 IN COMPLEX WITH INHIBITOR
Classification: KINASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.79 Å
Deposited: 2015-05-13
Authors: Tucker, J., Ogg, D.J.
PDB entry 4zsh: RXR LBD in complex with 9-cis-13,14-dihydroretinoic acid
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2015-05-13
Authors: Rochel, N., Krezel, W., Ruhl, R.
PDB entry 4zsi: Crystal structure of the effector-binding domain of DasR (DasR-EBD) in complex with glucosamine-6-phosphate
Classification: TRANSCRIPTION
Source organism: Streptomyces coelicolor A3(2)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.652 Å
Deposited: 2015-05-13
Authors: Fillenberg, S.B., Koerner, S., Muller, Y.A.
PDB entry 4zsj: MITOGEN ACTIVATED PROTEIN KINASE 7 IN COMPLEX WITH INHIBITOR
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.48 Å
Deposited: 2015-05-13
Authors: Tucker, J., Ogg, D.J.
PDB entry 4zsk: Crystal structure of the effector-binding domain of DasR (DasR-EBD) in complex with N-acetylglucosamine-6-phosphate
Classification: TRANSCRIPTION
Source organism: Streptomyces coelicolor A3(2)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2015-05-13
Authors: Fillenberg, S.B., Muller, Y.A.
PDB entry 4zsl: MITOGEN ACTIVATED PROTEIN KINASE 7 IN COMPLEX WITH INHIBITOR
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2015-05-13
Authors: Ogg, D.J., Tucker, J.
PDB entry 4zsm: BACE crystal structure with bicyclic aminothiazine fragment
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.96 Å
Deposited: 2015-05-13
Authors: Timm, D.E.
PDB entry 4zsn: 70S-wild-type HigB toxin complex bound to a AAA lysine codon
Classification: RIBOSOME
Source organism: Escherichia coli; Proteus vulgaris; Thermus thermophilus  HB8; Thermus thermophilus HB8; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.6 Å
Deposited: 2015-05-13
Authors: Schureck, M.A., Dunham, C.M.
PDB entry 4zso: Crystal structure of a complex between B7-H6, a tumor cell ligand for natural cytotoxicity receptor NKp30, and an inhibitory antibody
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2015-05-13
Authors: Xu, X., Li, Y., Mariuzza, R.A.
PDB entry 4zsp: BACE crystal structure with bicyclic aminothiazine inhibitor
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.91 Å
Deposited: 2015-05-13
Authors: Timm, D.E.
PDB entry 4zsq: BACE crystal structure with tricyclic aminothiazine inhibitor
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2015-05-13
Authors: Timm, D.E.
PDB entry 4zsr: BACE crystal structure with tricyclic aminothiazine inhibitor
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2015-05-13
Authors: Timm, D.E.
PDB entry 4zst: Crystal structure of Brevundimonas diminuta phosphotriesterase mutant L7eP-3a
Classification: HYDROLASE
Source organism: Brevundimonas diminuta
Experimental method: X-RAY DIFFRACTION
Resolution: 2.011 Å
Deposited: 2015-05-13
Authors: Mabanglo, M.F., Raushel, F.M.
PDB entry 4zsu: Crystal structure of Brevundimonas diminuta phosphotriesterase mutant L7eP-3aG
Classification: HYDROLASE
Source organism: Brevundimonas diminuta
Experimental method: X-RAY DIFFRACTION
Resolution: 2.011 Å
Deposited: 2015-05-14
Authors: Mabanglo, M.F., Raushel, F.M.
PDB entry 4zsv: Structure of a fusion protein with a helix linker, 2ARH-3-3KAW-1.0
Classification: UNKNOWN FUNCTION
Source organism: Aquifex aeolicus; Pseudomonas aeruginosa
Experimental method: X-RAY DIFFRACTION
Resolution: 4.2 Å
Deposited: 2015-05-14
Authors: Lai, Y.-T., Yeates, T.O.
PDB entry 4zsw: Pig Brain GABA-AT inactivated by (E)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic acid
Classification: transferase/transferase inhibitor
Source organism: Sus scrofa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2015-05-14
Authors: Wu, R., Lee, H., Le, H.V., Doud, E., Sanishvili, R., Compton, P., Kelleher, N.L., Silverman, R.B., Liu, D.
PDB entry 4zsx: Structure of a fusion protein with a helix linker, 2ARH-3-3KAW-2.0
Classification: UNKNOWN FUNCTION
Source organism: Aquifex aeolicus; Pseudomonas aeruginosa
Experimental method: X-RAY DIFFRACTION
Resolution: 2.19 Å
Deposited: 2015-05-14
Authors: Lai, Y.-T., Yeates, T.O.
PDB entry 4zsy: Pig Brain GABA-AT inactivated by (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic acid.
Classification: Transferase/Transferase inhibitor
Source organism: Sus scrofa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2015-05-14
Authors: Wu, R., Lee, H., Le, H.V., Doud, E., Sanishvili, R., Compton, P., Kelleher, N.L., Silverman, R.B., Liu, D.
PDB entry 4zsz: Structure of a fusion protein with a helix linker, 2ARH-3-3KAW-3.0
Classification: UNKNOWN FUNCTION
Source organism: Aquifex aeolicus (strain VF5); Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Experimental method: X-RAY DIFFRACTION
Resolution: 4.251 Å
Deposited: 2015-05-14
Authors: Lai, Y.-T., Yeates, T.O.
PDB entry 4zt0: Crystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolution
Classification: HYDROLASE/RNA
Source organism: Streptococcus pyogenes
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2015-05-14
Authors: Jiang, F., Doudna, J.A.
PDB entry 4zt1: Crystal structure of human E-Cadherin (residues 3-213) in x-dimer conformation
Classification: CELL ADHESION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.92 Å
Deposited: 2015-05-14
Authors: Nardone, V., Lucarelli, A.P., Dalle Vedove, A., Parisini, E.
PDB entry 4zt2: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-(3,5-dichlorobenzyl)-N'-(1H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1575)
Classification: Ligase/Ligase Inhibitor
Source organism: Trypanosoma brucei brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2015-05-14
Authors: Koh, C.-Y., Hol, W.G.J.
PDB entry 4zt3: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-(3,5-dichlorobenzyl)-N'-(5-fluoro-1H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1614)
Classification: Ligase/Ligase Inhibitor
Source organism: Trypanosoma brucei brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2015-05-14
Authors: Koh, C.-Y., Hol, W.G.J.
PDB entry 4zt4: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitorN-(3,5-dichlorobenzyl)-2,2-difluoro-N'-(1H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1708)
Classification: Ligase/Ligase Inhibitor
Source organism: Trypanosoma brucei brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2015-05-14
Authors: Koh, C.-Y., Hol, W.G.J.
PDB entry 4zt5: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (2S)-N-(3,5-dichlorobenzyl)-N'-(1H-imidazo[4,5-b]pyridin-2-yl)-2-methylpropane-1,3-diamine (Chem 1655)
Classification: Ligase/Ligase Inhibitor
Source organism: Trypanosoma brucei brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2015-05-14
Authors: Koh, C.-Y., Hol, W.G.J.
PDB entry 4zt6: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-[(4R)-6,8-dichloro-3,4-dihydro-2H-chromen-4-yl]-N'-(5-fluoro-1H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1709)
Classification: Ligase/Ligase Inhibitor
Source organism: Trypanosoma brucei brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2015-05-14
Authors: Koh, C.-Y., Hol, W.G.J.
PDB entry 4zt7: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-[(4R)-6,8-dichloro-1,2,3,4-tetrahydroquinolin-4-yl]-N'-(5-fluoro-3H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1717)
Classification: Ligase/Ligase Inhibitor
Source organism: Trypanosoma brucei brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2015-05-14
Authors: Koh, C.-Y., Hol, W.G.J.
PDB entry 4zt8: Structure of the complex of type 1 ribosome inactivating protein from Momordica balsamina with a pyrimidine base, cytosine at 1.98 A resolution
Classification: HYDROLASE
Source organism: Momordica balsamina
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2015-05-14
Authors: Yamini, S., Pandey, S., Kaur, P., Sharma, S., Singh, T.P.
PDB entry 4zt9: Nuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolution
Classification: HYDROLASE/RNA
Source organism: Streptococcus pyogenes
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1 Å
Deposited: 2015-05-14
Authors: Jiang, F., Doudna, J.A.
PDB entry 4zta: Ebola virus nucleoprotein bound to VP35 chaperoning peptide I212121
Classification: VIRAL PROTEIN
Source organism: Zaire ebolavirus (strain Mayinga-76)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2015-05-14
Authors: Kirchdoerfer, R.N., Abelson, D.M., Saphire, E.O.
PDB entry 4ztb: Crystal structure of nsP2 protease from Chikungunya virus in P212121 space group at 2.59 A (4molecules/ASU).
Classification: HYDROLASE
Source organism: Chikungunya virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.59 Å
Deposited: 2015-05-14
Authors: Narwal, M., Pratap, S., Singh, H., Kumar, P., Tomar, S.
PDB entry 4ztc: PglE Aminotransferase in complex with External Aldimine, Mutant K184A
Classification: TRANSFERASE
Source organism: Campylobacter jejuni
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-05-14
Authors: Riegert, A.S., Thoden, J.B., Young, N.M., Watson, D.C., Holden, H.M.
PDB entry 4ztd: Crystal Structure of Human PCNA in complex with a TRAIP peptide
Classification: REPLICATION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.199 Å
Deposited: 2015-05-14
Authors: Montoya, G., Mortuza, G.B., Blanco, F.J., Ibanez de Opakua, A.
PDB entry 4zte: Crystal structure of human E-Cadherin (residues 3-213) in complex with a peptidomimetic inhibitor
Classification: CELL ADHESION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.13 Å
Deposited: 2015-05-14
Authors: Nardone, V., Lucarelli, A.P., Dalle Vedove, A., Parisini, E.
PDB entry 4ztf: Crystal Structure of the Prototype Foamy Virus Intasome with a 2-Pyridinone Aminal Inhibitor
Classification: Transferase/DNA/Inhibitor
Source organism: Human spumaretrovirus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2015-05-14
Authors: Klein, D.J., Patel, S.
PDB entry 4ztg: Ebola virus nucleoprotein bound to VP35 chaperoning peptide P22121
Classification: VIRAL PROTEIN
Source organism: Zaire ebolavirus (strain Mayinga-76)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2015-05-14
Authors: Kirchdoerfer, R.N., Abelson, D.M., Saphire, E.O.
PDB entry 4zth: Structure of human p38aMAPK-arylpyridazinylpyridine fragment complex used in inhibitor discovery
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2015-05-14
Authors: Grum-Tokars, V.L., Roy, S.M., Watterson, D.M.
PDB entry 4zti: Ebola virus nucleoprotein bound to VP35 chaperoning peptide P212121
Classification: VIRAL PROTEIN
Source organism: Zaire ebolavirus (strain Mayinga-76)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2015-05-14
Authors: Kirchdoerfer, R.N., Abelson, D.M., Saphire, E.O.
PDB entry 4ztj: Crystal Structure of the Prototype Foamy Virus Intasome with a 2-Pyridinone Aminal Inhibitor
Classification: transferase/DNA/inhibitor
Source organism: Human spumaretrovirus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.67 Å
Deposited: 2015-05-14
Authors: Klein, D.J., Patel, S.
PDB entry 4ztk: Transpeptidase domain of FtsI4 D,D-transpeptidase from Legionella pneumophila.
Classification: Transferase, Cell Cycle
Source organism: Legionella pneumophila subsp. pneumophila ATCC 43290
Experimental method: X-RAY DIFFRACTION
Resolution: 2.104 Å
Deposited: 2015-05-14
Authors: CUFF, M., OSIPIUK, J., WU, R., ENDRES, M., JOACHIMIAK, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 4ztl: Irak4-inhibitor co-structure
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.39 Å
Deposited: 2015-05-14
Authors: Fischmann, T.O.
PDB entry 4ztm: Irak4-inhibitor co-structure
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.66 Å
Deposited: 2015-05-14
Authors: Fischmann, T.O.
PDB entry 4ztn: Irak4-inhibitor co-structure
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.23 Å
Deposited: 2015-05-14
Authors: Fischmann, T.O.
PDB entry 4zto: Fab/epitope complex structure of rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region
Classification: IMMUNE SYSTEM
Source organism: Oryctolagus cuniculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2015-05-14
Authors: Pan, R., Kong, X.-P.
PDB entry 4ztp: Fab structure of rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region
Classification: IMMUNE SYSTEM
Source organism: Oryctolagus cuniculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.63 Å
Deposited: 2015-05-14
Authors: Pan, R., Kong, X.-P.
PDB entry 4ztq: Human Aurora A catalytic domain bound to FK932
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2015-05-14
Authors: Marcaida, M.J., Kilchmann, F., Schick, T., Reymond, J.L.
PDB entry 4ztr: Human Aurora A catalytic domain bound to FK1141
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.85 Å
Deposited: 2015-05-15
Authors: Marcaida, M.J., Kilchmann, F., Schick, T., Reymond, J.L.
PDB entry 4zts: Human Aurora A catalytic domain bound to FK1142
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2015-05-15
Authors: Marcaida, M.J., Kilchmann, F., Schick, T., Reymond, J.L.
PDB entry 4ztt: Crystal structures of ferritin mutants reveal diferric-peroxo intermediates
Classification: OXIDOREDUCTASE
Source organism: Escherichia coli DH1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.83 Å
Deposited: 2015-05-15
Authors: Kim, S., Park, Y.H., Jung, S.W., Seok, J.H., Chung, Y.B., Lee, D.B., Gowda, G., Lee, J.H., Han, H.R., Cho, A.E., Lee, C., Chung, M.S., Kim, K.H.
PDB entry 4ztu: Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase
Classification: DNA Binding Protein/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.299 Å
Deposited: 2015-05-15
Authors: Szymanski, M.R., Kuznestov, V.B., Shumate, C.K., Meng, Q., Lee, Y.-S., Patel, G., Patel, S.S., Yin, Y.W.
PDB entry 4ztv: Non-anthranilate-like inhibitor (TAMU-A7) complexed with anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis in absence of PRPP
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.01 Å
Deposited: 2015-05-15
Authors: Evans, G.L., Eom, J., Baker, E.N., Lott, J.S., TB Structural Genomics Consortium (TBSGC)
PDB entry 4ztx: Neurospora crassa cobalamin-independent methionine synthase complexed with Zn2+
Classification: TRANSFERASE
Source organism: Neurospora crassa
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2015-05-15
Authors: Wheatley, R.W., Ng, K.K., Kapoor, M.
PDB entry 4zty: Neurospora crassa cobalamin-independent methionine synthase complexed with Cd2+
Classification: TRANSFERASE
Source organism: Neurospora crassa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.88 Å
Deposited: 2015-05-15
Authors: Wheatley, R.W., Ng, K.K., Kapoor, M.