LiteFold/PDB huggingface dataset:
PDB entry 5ul1: The co-structure of 3-amino-6-(4-((1-(dimethylamino)propan-2-yl)sulfonyl)phenyl)-N-phenylpyrazine-2-carboxamide and a rationally designed PI3K-alpha mutant that mimics ATR
Classification: TRANSFERASE/SIGNALING PROTEIN/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2017-01-23
Authors: Knapp, M.S., Elling, R.A., Mamo, M.
PDB entry 5ul2: Structure of Apo, SeMet-labeled Cobalamin-dependent S-adenosylmethionine radical enzyme OxsB
Classification: METAL BINDING PROTEIN
Source organism: Bacillus megaterium
Experimental method: X-RAY DIFFRACTION
Resolution: 2.552 Å
Deposited: 2017-01-24
Authors: Bridwell-Rabb, J., Drennan, C.L.
PDB entry 5ul3: Structure of Cobalamin-dependent S-adenosylmethionine radical enzyme OxsB with aqua-cobalamin bound
Classification: METAL BINDING PROTEIN
Source organism: Bacillus megaterium
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2017-01-24
Authors: Bridwell-Rabb, J., Drennan, C.L.
PDB entry 5ul4: Structure of Cobalamin-dependent S-adenosylmethionine radical enzyme OxsB with aqua-cobalamin and S-adenosylmethionine bound
Classification: METAL BINDING PROTEIN
Source organism: Bacillus megaterium
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2017-01-24
Authors: Bridwell-Rabb, J., Drennan, C.L.
PDB entry 5ul5: Crystal structure of RPE65 in complex with MB-004 and palmitate
Classification: ISOMERASE/ISOMERASE INHIBITOR
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2017-01-24
Authors: Kiser, P.D., Palczewski, K.
PDB entry 5ul6: The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions
Classification: VIRAL PROTEIN
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2017-01-24
Authors: Shen, Q., Zeng, D., Zhao, B., Li, P., Cho, J.H.
PDB entry 5ul7: Structure and function of the divalent anion/Na+ symporter from Vibrio cholerae and a humanized variant
Classification: TRANSPORT PROTEIN
Source organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2017-01-24
Authors: Lu, M.
PDB entry 5ul8: Apo KPC-2 beta-lactamase crystal structure at 1.15 Angstrom resolution
Classification: HYDROLASE
Source organism: Klebsiella pneumoniae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.15 Å
Deposited: 2017-01-24
Authors: Pemberton, O.A., Chen, Y.
PDB entry 5ul9: Structure and function of the divalent anion/Na+ symporter from Vibrio cholerae and a humanized variant
Classification: TRANSPORT PROTEIN
Source organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.78 Å
Deposited: 2017-01-24
Authors: Lu, M.
PDB entry 5ula: Crystal Structure of the First Bromodomain of Human BRD4 in Complex With Cyclic Vinylogous Amide Inhibitor MS402
Classification: transcription/inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2017-01-24
Authors: Plotnikov, A.N., Joshua, j., Zhou, M.-M.
PDB entry 5ulb: Crystal structure of sugar ABC transporter from Yersinia enterocolitica subsp. enterocolitica 8081
Classification: SUGAR BINDING PROTEIN
Source organism: Yersinia enterocolitica subsp. enterocolitica 8081
Experimental method: X-RAY DIFFRACTION
Resolution: 1.28 Å
Deposited: 2017-01-24
Authors: Nocek, B., Bigelow, L., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5ulc: PLASMODIUM FALCIPARUM BROMODOMAIN-CONTAINING PROTEIN PF10_0328
Classification: SIGNALING PROTEIN
Source organism: Plasmodium falciparum (isolate 3D7)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2017-01-24
Authors: Wernimont, A.K., Amaya, M.F., Lam, A., Ali, A., Zhang, A.Z., Kenzina, L., Lin, Y.H., MacKenzie, F., Kozieradzki, I., Cossar, D., Schapira, M., Bochkarev, A., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Weigelt, J., Hui, R., Walker, J.R., Qiu, W., Brand, V., Structural Genomics Consortium (SGC)
PDB entry 5uld: Structure and function of the divalent anion/Na+ symporter from Vibrio cholerae and a humanized variant
Classification: TRANSPORT PROTEIN
Source organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.78 Å
Deposited: 2017-01-24
Authors: Lu, M.
PDB entry 5ule: Structure and function of the divalent anion/Na+ symporter from Vibrio cholerae and a humanized variant
Classification: TRANSPORT PROTEIN
Source organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2017-01-24
Authors: Lu, M.
PDB entry 5ulf: Crystal Structure of a UbcH5b~Ub conjugate
Classification: TRANSFERASE/SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2017-01-24
Authors: Middleton, A.J., Day, C.L., Wright, J.D.
PDB entry 5ulg: Crystal structure of RPE65 in complex with MB-008 and palmitate
Classification: ISOMERASE/ISOMERASE INHIBITOR
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2017-01-24
Authors: Kiser, P.D., Palczewski, K.
PDB entry 5ulh: Structure of RNF165 in complex with a UbcH5b~Ub conjugate
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2017-01-24
Authors: Middleton, A.J., Day, C.L., Wright, J.D.
PDB entry 5uli: Crystal Structure of mouse DXO in complex with (3'-NADP)+ and calcium ion
Classification: HYDROLASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2017-01-24
Authors: Doamekpor, S.K., Tong, L.
PDB entry 5ulj: Crystal structure of Scheffersomyces stipitis Rai1 in complex with (3'-NADP)+ and calcium ion
Classification: HYDROLASE
Source organism: Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.911 Å
Deposited: 2017-01-24
Authors: Doamekpor, S.K., Tong, L.
PDB entry 5ulk: Crystal Structure of RNF165 in complex with a UbcH5b~Ub conjugate
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.38 Å
Deposited: 2017-01-24
Authors: Middleton, A.J., Day, C.L., Wright, J.D.
PDB entry 5ull: CLOSTRIDIUM BEIJERINCKII FLAVODOXIN: REDUCED
Classification: ELECTRON TRANSPORT
Source organism: Clostridium beijerinckii
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 1997-01-09
Authors: Ludwig, M.L., Pattridge, K.A., Metzger, A.L., Dixon, M.M., Eren, M., Feng, Y., Swenson, R.
PDB entry 5ulm: Structure of the ASK1 central regulatory region
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2017-01-24
Authors: Mace, P.D., Kumar, A., Caradoc-Davies, T.T.
PDB entry 5uln: Synthesis of novel seleno ureido containing compounds as SLC-0111 analogs. Investigations on carbonic anhydrases activity, glutathione peroxidase and X-ray crystallography
Classification: LYASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.35 Å
Deposited: 2017-01-25
Authors: Peat, T.S., Angeli, A., Tanini, D., Bartolucci, G., Capperucci, A., Supuran, C.T., Carta, F.
PDB entry 5ulo: Crystal Structure of 14-3-3 zeta in Complex with a Serine 124-phosphorylated TBC1D7 peptide
Classification: SIGNALING PROTEIN/peptide
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.14 Å
Deposited: 2017-01-25
Authors: DONG, A., HU, J., MADIGAN, J., WALKER, J.R., Bountra, C., Arrowsmith, C.H., Edwards, A.M., TONG, Y., Structural Genomics Consortium (SGC)
PDB entry 5ulp: Structure of the NS5 methyltransferase from Zika bound to MS2042
Classification: HYDROLASE
Source organism: Zika virus (strain Mr 766)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2017-01-25
Authors: Jain, R., Aggarwal, A.K.
PDB entry 5uls: Structure of GRP94 in the active conformation
Classification: CHAPERONE
Source organism: Canis lupus familiaris
Experimental method: X-RAY DIFFRACTION
Resolution: 2.622 Å
Deposited: 2017-01-25
Authors: Huck, J.D., Que, N.L.S., Gewirth, D.T.
PDB entry 5ult: HIV-1 wild Type protease with GRL-100-13A (a Crown-like Oxotricyclic Core as the P2-Ligand with the sulfonamide isostere as the P2' group)
Classification: hydrolase/hydrolase inhibitor
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.53 Å
Deposited: 2017-01-25
Authors: Wang, Y.-F., Agniswamy, J., Weber, I.T.
PDB entry 5ulu: Crystal Structure of Mouse Cadherin-23 EC19-21 (S2087P) with non-syndromic deafness (DFNB12) associated mutation D2148N
Classification: CELL ADHESION
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.85 Å
Deposited: 2017-01-25
Authors: Jaiganesh, A., Sotomayor, M.
PDB entry 5ulv: Malate dehydrogenase from Methylobacterium extorquens
Classification: OXIDOREDUCTASE
Source organism: Methylobacterium extorquens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.66 Å
Deposited: 2017-01-25
Authors: Gonzalez, J.M.
PDB entry 5ulw: Structure of human DNA polymerase iota bound to template 1-methyl-deoxyadenosine
Classification: Thansferase/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.617 Å
Deposited: 2017-01-25
Authors: Jain, R., Aggarwal, A.K.
PDB entry 5ulx: Structure of human DNA polymerase iota bound to template 1-methyl-deoxyadenosine crystallized in the presence of dCTP
Classification: Thansferase/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.96 Å
Deposited: 2017-01-25
Authors: Jain, R., Aggarwal, A.K.
PDB entry 5uly: Crystal Structure of Human Protocadherin-15 EC2-3
Classification: Calcium-binding protein
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.64 Å
Deposited: 2017-01-25
Authors: Wimalasena, L.N., Sotomayor, M.
PDB entry 5um0: Crystal structure of 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase from Neisseria gonorrhoeae
Classification: ISOMERASE
Source organism: Neisseria gonorrhoeae (strain NCCP11945)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2017-01-25
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5um1: XFEL structure of influenza A M2 wild type TM domain at intermediate pH in the lipidic cubic phase at room temperature
Classification: PROTON TRANSPORT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.451 Å
Deposited: 2017-01-25
Authors: Thomaston, J.L., Woldeyes, R.A., Fraser, J.S., DeGrado, W.F.
PDB entry 5um2: Functional and structural characterization of a Sulfate-binding protein (Sbp) from Xanthomonas citri
Classification: TRANSPORT PROTEIN
Source organism: Xanthomonas axonopodis pv. citri
Experimental method: X-RAY DIFFRACTION
Resolution: 1.14 Å
Deposited: 2017-01-26
Authors: Pereira, C.T., Hyvonen, M., Balan, A.
PDB entry 5um3: Crystal structure of the V122L mutant of human UBR-box domain from UBR2
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.198 Å
Deposited: 2017-01-26
Authors: Munoz Escobar, J., Kozlov, G., Gehring, K.
PDB entry 5um4: Crystal structure of the F255A mutant Kir3.1 cytoplasmic pore domain
Classification: TRANSPORT PROTEIN
Source organism: Anolis carolinensis; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2017-01-26
Authors: Meinke, G., Bohm, A., Noujaim, S.
PDB entry 5um6: Crystal Structure of S. pombe Uba1 in a closed conformation
Classification: ligase/ligase inhibitor
Source organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.794 Å
Deposited: 2017-01-26
Authors: Lv, Z., Yuan, L., Aldana-Masangkay, G., Atkison, J.H., Chen, Y., Olsen, S.K.
PDB entry 5um7: Crystal structure of the reduced state of the thiol-disulfide reductase SdbA from Streptococcus gordonii
Classification: OXIDOREDUCTASE
Source organism: Streptococcus gordonii (strain Challis / ATCC 35105 / BCRC 15272 / CH1 / DL1 / V288)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.62 Å
Deposited: 2017-01-26
Authors: Stogios, P.J., Evdokimova, E., Wawrzak, Z., Yim, V., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5um8: Crystal structure of HIV-1 envelope trimer 16055 NFL TD CC (T569G) in complex with Fabs 35022 and PGT124
Classification: Viral Protein/Immune System
Source organism: Homo sapiens; Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 3.935 Å
Deposited: 2017-01-26
Authors: Garces, F., Stanfield, R.L., Wilson, I.A.
PDB entry 5um9: Flap endonuclease 1 (FEN1) D86N with 5'-flap substrate DNA and Sm3+
Classification: Hydrolase/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.805 Å
Deposited: 2017-01-26
Authors: Tsutakawa, S.E., Arvai, A.S., Tainer, J.A.
PDB entry 5umb: Crystal structure of ATPase domain of Malaria GRP78 with ADP bound
Classification: CHAPERONE
Source organism: Plasmodium falciparum NF54
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2017-01-26
Authors: Chen, Y., Antoshchenko, T., Pizarro, J.C., Song, J.H., Park, H.
PDB entry 5umc: Synthesis of novel seleno ureido containing compounds as SLC-0111 analogs. Investigations on carbonic anhydrases activity, glutathione peroxidase and X-ray crystallography
Classification: LYASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2017-01-26
Authors: Peat, T.S., Angeli, A., Tanini, D., Bartolucci, G., Capperucci, A., Supuran, C.T., Carta, F.
PDB entry 5umd: Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine
Classification: RIBOSOME
Source organism: Plasmodium falciparum 3D7
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.2 Å
Deposited: 2017-01-27
Authors: Wong, W., Bai, X.-C., Brown, A., Scheres, S., Baum, J.
PDB entry 5ume: Crystal Structure of 5,10-Methylenetetrahydrofolate Reductase MetF from Haemophilus influenzae
Classification: OXIDOREDUCTASE
Source organism: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2017-01-27
Authors: Kim, Y., Mulligan, R., Maltseva, N., Grimshaw, S., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5umf: Crystal Structure of a Ribulose-phosphate 3-epimerase from Neisseria gonorrhoeae with bound phosphate
Classification: ISOMERASE
Source organism: Neisseria gonorrhoeae (strain NCCP11945)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2017-01-27
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5umg: Crystal structure of dihydropteroate synthase from Klebsiella pneumoniae subsp.
Classification: TRANSFERASE
Source organism: Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.601 Å
Deposited: 2017-01-27
Authors: Chang, C., Zhou, M., Grimshaw, S., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5umh: Crystal Structure of Catechol 1,2-dioxygenase protein from Burkholderia multivorans
Classification: OXIDOREDUCTASE
Source organism: Burkholderia multivorans (strain ATCC 17616 / 249)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.35 Å
Deposited: 2017-01-27
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5umi: Clostridium difficile TcdA-CROPs bound to PA50 Fab
Classification: TOXIN/IMMUNE SYSTEM
Source organism: Clostridioides difficile; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.23 Å
Deposited: 2017-01-27
Authors: Kroh, H.K., Chandrasekaran, R., Rosenthal, K., Woods, R., Jin, X., Ohi, M.D., Nyborg, A.C., Rainey, G.J., Warrener, P., Spiller, B.W., Lacy, D.B.
PDB entry 5umj: Crystal structure of H62A mutant of human macrophage migration inhibitory factor
Classification: ISOMERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.61 Å
Deposited: 2017-01-27
Authors: Pantouris, G., Lolis, E.
PDB entry 5umk: Crystal structure of H62Y mutant of human macrophage migration inhibitory factor
Classification: ISOMERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.73 Å
Deposited: 2017-01-27
Authors: Pantouris, G., Lolis, E.
PDB entry 5uml: CRYSTAL STRUCTURE OF HUMAN MDMX IN COMPLEX WITH 12-MER PEPTIDE INHIBITOR M3
Classification: Cell Cycle,Antitumor Protein/Inhibitor
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2017-01-27
Authors: Pazgier, M., Gohain, N., Tolbert, W.D.
PDB entry 5umm: CRYSTAL STRUCTURE OF HUMAN MDM2 IN COMPLEX WITH 12-MER PEPTIDE INHIBITOR M3
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2017-01-27
Authors: Pazgier, M., Gohain, N., Tolbert, W.D.
PDB entry 5umn: Crystal structure of C05 VPGSGW mutant bound to H3 influenza hemagglutinin, HA1 subunit
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.97 Å
Deposited: 2017-01-27
Authors: Wu, N.C., Wilson, I.A.
PDB entry 5umo: STRUCTURE OF EXTRACELLULAR SIGNAL-REGULATED KINASE
Classification: TRANSFERASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.26 Å
Deposited: 2017-01-27
Authors: CHLEBOWICZ, J., ZHANG, F., GOLDSMITH, E.J.
PDB entry 5ump: Crystal structure of TnmS3, an antibiotic binding protein from Streptomyces sp. CB03234
Classification: Tiancimycin-binding protein
Source organism: Streptomyces sp. CB03234
Experimental method: X-RAY DIFFRACTION
Resolution: 1.08 Å
Deposited: 2017-01-29
Authors: Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips Jr., G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
PDB entry 5umq: Crystal structure of TnmS1, an antibiotic binding protein from Streptomyces sp. CB03234
Classification: Tiancimycin-binding protein
Source organism: Streptomyces sp. CB03234
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2017-01-29
Authors: Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips Jr., G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
PDB entry 5umr: Crystal structure of N-terminal domain of human FACT complex subunit SSRP1
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.501 Å
Deposited: 2017-01-29
Authors: Su, D., Hu, Q., Thompson, J.R., Heroux, A., Botuyan, M.V., Mer, G.
PDB entry 5ums: Crystal structure of middle double PH domain of human FACT complex subunit SSRP1
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.569 Å
Deposited: 2017-01-29
Authors: Su, D., Hu, Q., Thompson, J.R., Botuyan, M.V., Mer, G.
PDB entry 5umt: Crystal structure of N-terminal domain of human FACT complex subunit SPT16
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.092 Å
Deposited: 2017-01-29
Authors: Su, D., Hu, Q., Thompson, J.R., Botuyan, M.V., Mer, G.
PDB entry 5umu: Crystal structure of the middle double PH domain of human FACT complex subunit SPT16
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.903 Å
Deposited: 2017-01-29
Authors: Hu, Q., Thompson, J.R., Heroux, A., Su, D., Botuyan, M.V., Mer, G.
PDB entry 5umv: Crystal structure of the BRCT domain of S. cerevisiae Rev1
Classification: TRANSCRIPTION
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2017-01-29
Authors: Lee, J., Xu, C., Thompson, J.R., Botuyan, M.V., Mer, G.
PDB entry 5umw: Crystal structure of TnmS2, an antibiotic binding protein from Streptomyces sp. CB03234
Classification: Tiancimycin-binding protein
Source organism: Streptomyces sp. CB03234
Experimental method: X-RAY DIFFRACTION
Resolution: 2.27 Å
Deposited: 2017-01-29
Authors: Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips Jr., G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
PDB entry 5umx: Crystal structure of TnmS3 in complex with riboflavin
Classification: Tiancimycin-binding protein
Source organism: Streptomyces sp. CB03234
Experimental method: X-RAY DIFFRACTION
Resolution: 1.59 Å
Deposited: 2017-01-29
Authors: Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips Jr., G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
PDB entry 5umy: Crystal structure of TnmS3 in complex with tiancimycin
Classification: Tiancimycin-binding protein
Source organism: Streptomyces sp. CB03234
Experimental method: X-RAY DIFFRACTION
Resolution: 1.78 Å
Deposited: 2017-01-29
Authors: Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips Jr., G.N., SHen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
PDB entry 5umz: Structure of TNRC6A NLS in complex with importin-alpha
Classification: PROTEIN TRANSPORT
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2017-01-30
Authors: Chaston, J., Stewart, A.G., Christie, M.
PDB entry 5un0: Crystal Structure of Mycobacterium Tuberculosis Proteasome-assembly chaperone homologue Rv2125
Classification: APOPTOSIS
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2017-01-30
Authors: Bai, L., Jastrab, J.B., Hu, K., Yu, H., Darwin, K.H., Li, H.
PDB entry 5un1: Crystal structure of GluN1/GluN2B delta-ATD NMDA receptor
Classification: MEMBRANE PROTEINS/INHIBITOR
Source organism: Xenopus laevis
Experimental method: X-RAY DIFFRACTION
Resolution: 3.6 Å
Deposited: 2017-01-30
Authors: Song, X., Gouaux, E.
PDB entry 5un2: Crystal Structure of Mouse Cadherin-23 EC19-21 with non-syndromic deafness (DFNB12) associated mutation R2029W
Classification: CELL ADHESION
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.96 Å
Deposited: 2017-01-30
Authors: Jaiganesh, A., Sotomayor, M.
PDB entry 5un3: Tetragonal thermolysin (295 K) in the presence of 50% xylose
Classification: HYDROLASE
Source organism: Bacillus thermoproteolyticus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.60004 Å
Deposited: 2017-01-30
Authors: Juers, D.
PDB entry 5un5: Frizzled-8 complex with designed surrogate Wnt agonist, crystal form 1
Classification: SIGNALING PROTEIN/De Novo Protein
Source organism: Homo sapiens; synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 2.994 Å
Deposited: 2017-01-30
Authors: Janda, C.Y., Garcia, K.C.
PDB entry 5un6: Frizzled-8 complex with designed surrogate Wnt agonist, A1 dataset
Classification: SIGNALING PROTEIN/DE NOVO PROTEIN
Source organism: Homo sapiens; synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2 Å
Deposited: 2017-01-30
Authors: Janda, C.Y., Garcia, K.C., Jude, K.M.
PDB entry 5un7: Structure of the human POT1-TPP1 telomeric complex
Classification: PROTEIN BINDING
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2017-01-30
Authors: Rice, C., Doukov, T., Skordalakes, E.
PDB entry 5un8: Crystal Structure of human O-GlcNAcase in complex with glycopeptide p53
Classification: HYDROLASE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.13 Å
Deposited: 2017-01-30
Authors: Li, B., Jiang, J.
PDB entry 5un9: The crystal structure of human O-GlcNAcase in complex with Thiamet-G
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2017-01-30
Authors: Li, B., Jiang, J.
PDB entry 5una: Fragment of 7SK snRNA methylphosphate capping enzyme
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.55 Å
Deposited: 2017-01-30
Authors: Wu, H., Tempel, W., Dombrovski, L., McCarthy, A.A., Loppnau, P., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Park, H., Structural Genomics Consortium (SGC)
PDB entry 5unb: Crystal structure of putative Putative deoxyribonuclease-2 from Burkholderia thailandensis in complex with copper
Classification: HYDROLASE
Source organism: Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2017-01-30
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5unc: The crystal structure of PHOSPHOENOLPYRUVATE PHOSPHOMUTASE from Streptomyces platensis subsp. rosaceus
Classification: ISOMERASE
Source organism: Streptomyces platensis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.71 Å
Deposited: 2017-01-30
Authors: Tan, K., Hatzos-Skintges, C., Endres, M., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
PDB entry 5und: Crystal Structure of CTCF(ZnF 4-10) With 28-mer DNA
Classification: transcription/dna
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.549 Å
Deposited: 2017-01-30
Authors: Horton, J.R., Cheng, X.
PDB entry 5une: Dimerized Structure Gives Further Insight Into the Function of the Novel RNA Gene: HAR1
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9001 Å
Deposited: 2017-01-30
Authors: Lares, M., Scott, W.G.
PDB entry 5unf: XFEL structure of human angiotensin II type 2 receptor (Monoclinic form) in complex with compound 1 (N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl])
Classification: SIGNALING PROTEIN
Source organism: Escherichia coli; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2017-01-30
Authors: Zhang, H., Han, G.W., Batyuk, A., Ishchenko, A., White, K.L., Patel, N., Sadybekov, A., Zamlynny, B., Rudd, M.T., Hollenstein, K., Tolstikova, A., White, T.A., Hunter, M.S., Weierstall, U., Liu, W., Babaoglu, K., Moore, E.L., Katz, R.D., Shipman, J.M., Garcia-Calvo, M., Sharma, S., Sheth, P., Soisson, S.M., Stevens, R.C., Katritch, V., Cherezov, V.
PDB entry 5ung: XFEL structure of human angiotensin II type 2 receptor (Orthorhombic form) in complex with compound 1 (N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl] methyl}-3,4-dihydroquinazolin-6-yl)thiophene-2-carboxamide)
Classification: SIGNALING PROTEIN
Source organism: Escherichia coli; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2017-01-30
Authors: Zhang, H., Han, G.W., Batyuk, A., Ishchenko, A., White, K.L., Patel, N., Sadybekov, A., Zamlynny, B., Rudd, M.T., Hollenstein, K., Tolstikova, A., White, T.A., Hunter, M.S., Weierstall, U., Liu, W., Babaoglu, K., Moore, E.L., Katz, R.D., Shipman, J.M., Garcia-Calvo, M., Sharma, S., Sheth, P., Soisson, S.M., Stevens, R.C., Katritch, V., Cherezov, V.
PDB entry 5unh: Synchrotron structure of human angiotensin II type 2 receptor in complex with compound 2 (N-[(furan-2-yl)methyl]-N-(4-oxo-2-propyl-3-{[2'-(2H-tetrazol-5-yl)[1,1'- biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)benzamide)
Classification: SIGNALING PROTEIN
Source organism: Escherichia coli; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2017-01-30
Authors: Zhang, H., Han, G.W., Batyuk, A., Ishchenko, A., White, K.L., Patel, N., Sadybekov, A., Zamlynny, B., Rudd, M.T., Hollenstein, K., Tolstikova, A., White, T.A., Hunter, M.S., Weierstall, U., Liu, W., Babaoglu, K., Moore, E.L., Katz, R.D., Shipman, J.M., Garcia-Calvo, M., Sharma, S., Sheth, P., Soisson, S.M., Stevens, R.C., Katritch, V., Cherezov, V.
PDB entry 5uni: Critical role of water molecules for proton translocation of the membrane-bound transhydrogenase
Classification: OXIDOREDUCTASE
Source organism: Thermus thermophilus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2017-01-30
Authors: Padayatti, P.S., Leung, J.H.
PDB entry 5unj: Structure of Human Liver Receptor Homolog 1 in complex with PGC1a and RJW100
Classification: NUCLEAR PROTEIN
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.959 Å
Deposited: 2017-01-31
Authors: Mays, S.G., Ortlund, E.A.
PDB entry 5unk: NMR structure of the RED subdomain of the Sleeping Beauty transposase
Classification: DNA BINDING PROTEIN
Source organism: Oncorhynchus mykiss
Experimental method: SOLUTION NMR
Deposited: 2017-01-31
Authors: Konnova, T.A., Singer, C.M., Nesmelova, I.V.
PDB entry 5unl: Crystal structure of a D-beta-hydroxybutyrate dehydrogenase from Burkholderia multivorans
Classification: OXIDOREDUCTASE
Source organism: Burkholderia multivorans
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2017-01-31
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5unm: LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase, substrate free form with flexible loop
Classification: TRANSFERASE
Source organism: Lactobacillus plantarum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.58 Å
Deposited: 2017-01-31
Authors: Fellner, M., Desguin, B., Hausinger, R.P., Hu, J.
PDB entry 5unn: Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase SMc02828 (SmGhrA) from Sinorhizobium meliloti in apo form
Classification: OXIDOREDUCTASE
Source organism: Rhizobium meliloti (strain 1021)
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2017-01-31
Authors: Shabalin, I.G., LaRowe, C., Kutner, J., Gasiorowska, O.A., Handing, K.B., Bonanno, J., Almo, S.C., Minor, W., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 5uno: Crystal Structure of Hip1 (Rv2224c)
Classification: HYDROLASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.603 Å
Deposited: 2017-01-31
Authors: Naffin-Olivos, J.L., Daab, A., White, A., Goldfarb, N., Milne, A.C., Liu, D., Dunn, B.M., Rengarajan, J., Petsko, G.A., Ringe, D.
PDB entry 5unp: Structure of CDC2-Like Kinase 2 (CLK2) in Complex with Compound T-025 [N2-methyl-N4-(pyrimidin-2-ylmethyl)-5-(quinolin-6-yl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine]
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.92 Å
Deposited: 2017-01-31
Authors: Klein, M.G., Tjhen, R.
PDB entry 5unq: Crystal Structure of Pt0534 Inactivated by 2-Oxo-3-pentynoate
Classification: HYDROLASE
Source organism: Pusillimonas sp. (strain T7-7)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.976 Å
Deposited: 2017-01-31
Authors: LeVieux, J., Baas, B.J., Zhang, Y.J., Whitman, C.P.
PDB entry 5unr: Structure of rat neuronal nitric oxide synthase heme domain in complex with 3-[(2-aminoquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5uns: Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-[(3-Ethyl-5-((methylamino)methyl)phenoxy)methyl]quinolin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5unt: Structure of rat neuronal nitric oxide synthase heme domain in complex with 4-Methyl-7-[(3-((methylamino)methyl)phenoxy)methyl]quinolin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5unu: Structure of rat neuronal nitric oxide synthase heme domain in complex with 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5unv: Structure of rat neuronal nitric oxide synthase heme domain in complex with 4-Methyl-7-[3-((methylamino)methyl)phenethyl]quinolin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5unw: Structure of rat neuronal nitric oxide synthase heme domain in complex with 3-[2-(2-amino-4-methylquinolin-7-yl)ethyl]-5-((methylamino)methyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.044 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5unx: Structure of rat neuronal nitric oxide synthase heme domain in complex with 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)ethyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.03 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5uny: Structure of rat neuronal nitric oxide synthase heme domain in complex with (RS)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.82 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5unz: Structure of rat neuronal nitric oxide synthase heme domain in complex with (R)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5uo0: Structure of rat neuronal nitric oxide synthase heme domain in complex with (S)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.97 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5uo1: Structure of human neuronal nitric oxide synthase heme domain in complex with 3-[(2-aminoquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5uo2: Structure of human neuronal nitric oxide synthase heme domain in complex with 7-[(3-Ethyl-5-((methylamino)methyl)phenoxy)methyl]quinolin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.947 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5uo3: Structure of human neuronal nitric oxide synthase heme domain in complex with 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5uo4: Structure of human neuronal nitric oxide synthase heme domain in complex with 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)ethyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5uo5: Structure of human neuronal nitric oxide synthase heme domain in complex with (RS)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5uo6: Structure of human neuronal nitric oxide synthase heme domain in complex with (R)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.96 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5uo7: Structure of human neuronal nitric oxide synthase heme domain in complex with (S)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.06 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5uo8: Structure of human endothelial nitric oxide synthase heme domain in complex with 3-[(2-aminoquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.18 Å
Deposited: 2017-01-31
Authors: Chreifi, G., Li, H., Poulos, T.L.
PDB entry 5uo9: Structure of human endothelial nitric oxide synthase heme domain in complex with 7-[(3-Ethyl-5-((methylamino)methyl)phenoxy)methyl]quinolin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.19 Å
Deposited: 2017-01-31
Authors: Chreifi, G., Li, H., Poulos, T.L.
PDB entry 5uoa: Structure of human endothelial nitric oxide synthase heme domain in complex with 3-[(2-Amino-4-methylquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2017-01-31
Authors: Chreifi, G., Li, H., Poulos, T.L.
PDB entry 5uob: Structure of human endothelial nitric oxide synthase heme domain in complex with (R)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.292 Å
Deposited: 2017-01-31
Authors: Chreifi, G., Li, H., Poulos, T.L.
PDB entry 5uoc: Structure of human endothelial nitric oxide synthase heme domain in complex with (S)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2017-01-31
Authors: Chreifi, G., Li, H., Poulos, T.L.
PDB entry 5uod: Structure of bovine endothelial nitric oxide synthase heme domain in complex with 3-[(2-Amino-4-methylquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.01 Å
Deposited: 2017-01-31
Authors: Li, H., Poulos, T.L.
PDB entry 5uoe: Crystal Structure Analysis of Elbow-Engineered-Fab-Bound Human Insulin Degrading Enzyme (IDE)
Classification: Hydrolase/Immune System
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.8 Å
Deposited: 2017-01-31
Authors: Liang, W.G., Bailey, L., Kossiakoff, T., Tang, W.J.
PDB entry 5uof: Crystal structure of alpha,alpha-trehalose 6-phosphate sythase from Burkholderia multivorans
Classification: TRANSFERASE
Source organism: Burkholderia multivorans (strain ATCC 17616 / 249)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2017-01-31
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5uog: Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase SMc04462 (SmGhrB) from Sinorhizobium meliloti in apo form
Classification: OXIDOREDUCTASE
Source organism: Rhizobium meliloti (strain 1021)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2017-01-31
Authors: Shabalin, I.G., Handing, K.B., Gasiorowska, O.A., Cooper, D.R., Bonanno, J., Almo, S.C., Minor, W., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 5uoh: Crystal Structure of Hip1 (Rv2224c) T466A mutant
Classification: HYDROLASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.609 Å
Deposited: 2017-01-31
Authors: Naffin-Olivos, J.L., Daab, A., White, A., Goldfarb, N., Milne, A.C., Liu, D., Baikovitz, J., Dunn, B.M., Rengarajan, J., Petsko, G.A., Ringe, D.
PDB entry 5uoi: Solution structure of the de novo mini protein HHH_rd1_0142
Classification: DE NOVO PROTEIN
Source organism: Escherichia coli
Experimental method: SOLUTION NMR
Deposited: 2017-01-31
Authors: Houliston, S., Rocklin, G.J., Lemak, A., Carter, L., Chidyausiku, T.M., Baker, D., Arrowsmith, C.H.
PDB entry 5uoj: THE STRUCTURE OF THE MAP KINASE P38 AT 2.1 ANGSTROMS RESOLUTION
Classification: TRANSFERASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2017-01-31
Authors: CHLEBOWICZ, J., WANG, Z., GOLDSMITH, E.J.
PDB entry 5uoo: BRD4 bromodomain 2 in complex with CD161
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.69 Å
Deposited: 2017-02-01
Authors: Meagher, J.L., Stuckey, J.A.
PDB entry 5uop: CRYSTAL STRUCTURE OF THE PROTOTYPE FOAMY VIRUS INTASOME WITH A 2- PYRIDINONE AMINAL INHIBITOR (COMPOUND 18)
Classification: TRANSFERASE/DNA/INHIBITOR
Source organism: Human spumaretrovirus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.85 Å
Deposited: 2017-02-01
Authors: Klein, D.J.
PDB entry 5uoq: CRYSTAL STRUCTURE OF THE PROTOTYPE FOAMY VIRUS INTASOME WITH A 2- PYRIDINONE AMINAL INHIBITOR (COMPOUND 31)
Classification: TRANSFERASE/DNA/INHIBITOR
Source organism: Human spumaretrovirus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.61 Å
Deposited: 2017-02-01
Authors: Klein, D.J.
PDB entry 5uor: Structure-Based Design of ASK1 Inhibitors as Potential First-in-Class Agents for Heart Failure
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.75 Å
Deposited: 2017-02-01
Authors: Dougan, D.R.
PDB entry 5uos: Crystal Structure of CblC (MMACHC) (1-238), a human B12 processing enzyme, complexed with an Antivitamin B12
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.51 Å
Deposited: 2017-02-01
Authors: Shanmuganathan, A., Karasik, A., Ruetz, M., Banerjee, R., Krautler, B., Koutmos, M.
PDB entry 5uot: CryoEM structure of the helical assembly of full length MxB
Classification: ANTIVIRAL PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.6 Å
Deposited: 2017-02-01
Authors: Perilla, J.R., Alvarez, F.J.D., Zhang, P., Schulten, K.
PDB entry 5uou: High resolution structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase from Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Classification: LYASE
Source organism: Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2017-02-01
Authors: Chang, C., Li, H., Bearden, J., Joachimiak, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5uov: HIV-1 wild Type protease with GRL-1118A , an isophthalamide-derived P2-P3 ligand with the sulfonamide isostere as the P2' group
Classification: hydrolase/hydrolase inhibitor
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.33 Å
Deposited: 2017-02-01
Authors: Wang, Y.-F., Agniswamy, J., Weber, I.T.
PDB entry 5uow: Triheteromeric NMDA receptor GluN1/GluN2A/GluN2B in complex with glycine, glutamate, MK-801 and a GluN2B-specific Fab, at pH 6.5
Classification: MEMBRANE PROTEIN
Source organism: Mus musculus; Xenopus laevis
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.5 Å
Deposited: 2017-02-01
Authors: Lu, W., Du, J., Goehring, A., Gouaux, E.
PDB entry 5uox: Structure-Based Design of ASK1 Inhibitors as Potential First-in-Class Agents for Heart Failure
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2017-02-01
Authors: Dougan, D.R.
PDB entry 5uoy: Crystal structure of human PDE1B catalytic domain in complex with inhibitor 16j (6-(4-Methoxybenzyl)-9-((tetrahydro-2H-pyran-4-yl)methyl)-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one)
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.82 Å
Deposited: 2017-02-01
Authors: Cedervall, E.P., Allerston, C.K., Xu, R., Sridhar, V., Barker, R., Aertgeerts, K.
PDB entry 5uoz: Insulin with proline analog FyP at position B28 in the T2 state
Classification: HORMONE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.17464 Å
Deposited: 2017-02-01
Authors: Lieblich, S.A., Fang, K.Y., Tirrell, D.A.
PDB entry 5up0: Crystal structure of human PDE1B catalytic domain in complex with inhibitor 3 (6-(4-chlorobenzyl)-8,9,10,11-tetrahydrobenzo[4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one)
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.04 Å
Deposited: 2017-02-01
Authors: Cedervall, E.P., Allerston, C.K., Xu, R., Sridhar, V., Barker, R., Aertgeerts, K.
PDB entry 5up1: Solution structure of the de novo mini protein EEHEE_rd3_1049
Classification: DE NOVO PROTEIN
Source organism: Escherichia coli
Experimental method: SOLUTION NMR
Deposited: 2017-02-01
Authors: Houliston, S., Rocklin, G.J., Lemak, A., Carter, L., Chidyausiku, T.M., Baker, D., Arrowsmith, C.H.
PDB entry 5up2: Triheteromeric NMDA receptor GluN1/GluN2A/GluN2B in complex with glycine, glutamate, Ro 25-6981, MK-801 and a GluN2B-specific Fab, at pH 6.5
Classification: MEMBRANE PROTEIN
Source organism: Mus musculus; Xenopus laevis
Experimental method: ELECTRON MICROSCOPY
Resolution: 6 Å
Deposited: 2017-02-01
Authors: Lu, W., Du, J., Goehring, A., Gouaux, E.
PDB entry 5up3: Structure-Based Design of ASK1 Inhibitors as Potential First-in-Class Agents for Heart Failure
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.95 Å
Deposited: 2017-02-01
Authors: Dougan, D.R.
PDB entry 5up4: Structure of the HIV-1 Capsid Protein and spacer peptide 1 by Cryo-EM
Classification: VIRUS
Source organism: Human immunodeficiency virus 1
Experimental method: ELECTRON MICROSCOPY
Resolution: 9 Å
Deposited: 2017-02-01
Authors: Perilla, J.R., Schirra, R., Zhang, P., Schulten, K.
PDB entry 5up5: Solution structure of the de novo mini protein EHEE_rd1_0284
Classification: DE NOVO PROTEIN
Source organism: Escherichia coli
Experimental method: SOLUTION NMR
Deposited: 2017-02-01
Authors: Houliston, S., Rocklin, G.J., Lemak, A., Carter, L., Chidyausiku, T.M., Baker, D., Arrowsmith, C.H.
PDB entry 5up7: Crystal Structure of the Ni-bound Human Heavy-Chain Ferritin 122H-delta C-star variant
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.79 Å
Deposited: 2017-02-01
Authors: Bailey, J.B., Zhang, L., Chiong, J.A., Ahn, S., Tezcan, F.A.