LiteFold/PDB huggingface dataset:
PDB entry 4qol: Structure of Bacillus pumilus catalase
Classification: OXIDOREDUCTASE
Source organism: Bacillus pumilus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2014-06-20
Authors: Loewen, P.C.
PDB entry 4qom: Bacillus pumilus catalase with pyrogallol bound
Classification: OXIDOREDUCTASE
Source organism: Bacillus pumilus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2014-06-20
Authors: Loewen, P.C.
PDB entry 4qon: Structure of Bacillus pumilus catalase with catechol bound.
Classification: OXIDOREDUCTASE
Source organism: Bacillus pumilus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2014-06-20
Authors: Loewen, P.C.
PDB entry 4qoo: Structure of Bacillus pumilus catalase with resorcinol bound.
Classification: OXIDOREDUCTASE
Source organism: Bacillus pumilus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2014-06-20
Authors: Loewen, P.C.
PDB entry 4qop: Structure of Bacillus pumilus catalase with hydroquinone bound.
Classification: OXIDOREDUCTASE
Source organism: Bacillus pumilus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2014-06-20
Authors: Loewen, P.C.
PDB entry 4qoq: Structure of Bacillus pumilus catalase with guaiacol bound
Classification: OXIDOREDUCTASE
Source organism: Bacillus pumilus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2014-06-20
Authors: Loewen, P.C.
PDB entry 4qor: Structure of Bacillus pumilus catalase with chlorophenol bound.
Classification: OXIDOREDUCTASE
Source organism: Bacillus pumilus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2014-06-20
Authors: Loewen, P.C.
PDB entry 4qos: CRYSTAL STRUCTURE OF PSPF(1-265) E108Q MUTANT bound to ADP
Classification: TRANSCRIPTION
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.42 Å
Deposited: 2014-06-20
Authors: Darbari, V.C., Lawton, E., Lu, D., Burrows, P.C., Wiesler, S., Joly, N., Zhang, N., Zhang, X., Buck, M.
PDB entry 4qot: Crystal structure of human copper chaperone bound to the platinum ion
Classification: CHAPERONE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2014-06-20
Authors: Belviso, B.D., Galliani, A., Caliandro, R., Arnesano, F., Natile, G.
PDB entry 4qox: Crystal Structure of CDPK4 from Plasmodium Falciparum, PF3D7_0717500
Classification: TRANSFERASE
Source organism: Plasmodium falciparum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.748 Å
Deposited: 2014-06-20
Authors: Wernimont, A.K., Walker, J.R., Hutchinson, A., Seitova, A., He, H., Loppnau, P., Neculai, M., Amani, M., Lin, Y.H., Ravichandran, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Lovato, D.V., Structural Genomics Consortium (SGC)
PDB entry 4qoy: Novel binding motif and new flexibility revealed by structural analysis of a pyruvate dehydrogenase-dihydrolipoyl acetyltransferase sub-complex from the escherichia coli pyruvate dehydrogenase multi-enzyme complex
Classification: OXIDOREDUCTASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2014-06-20
Authors: Furey, W., Arjunan, P.
PDB entry 4qoz: Crystal structure of the histone mRNA stem-loop, stem-loop binding protein (phosphorylated), and 3'hExo ternary complex
Classification: RNA/HYDROLASE/RNA BINDING PROTEIN
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.304 Å
Deposited: 2014-06-21
Authors: Tan, D., Tong, L.
PDB entry 4qp0: Crystal Structure Analysis of the Endo-1,4-beta-mannanase from Rhizomucor miehei
Classification: HYDROLASE
Source organism: Rhizomucor miehei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2014-06-22
Authors: Zheng, Q.J., Peng, Z., Liu, Y., Yan, Q.J., Chen, Z.Z., Qin, Z.
PDB entry 4qp1: Crystal structure of ERK2 in complex with N-cyclohexyl-9H-purin-6-amine
Classification: transferase/transferase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2014-06-22
Authors: Yin, J., Wang, W.
PDB entry 4qp2: Crystal Structure of ERKs in complex with 5-chlorobenzo[d]oxazol-2-amine
Classification: transferase/transferase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.23 Å
Deposited: 2014-06-22
Authors: Yin, J., Wang, W.
PDB entry 4qp3: Crystal Structure of ERK2 in complex with (S)-2-((9H-purin-6-yl)amino)-3-phenylpropan-1-ol
Classification: transferase/transferase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.599 Å
Deposited: 2014-06-22
Authors: Yin, J., Wang, W.
PDB entry 4qp4: Crystal Structure of ERK2 in complex with N-cyclohexyl-9H-purin-6-amine
Classification: transferase/transferase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2014-06-22
Authors: Yin, J., Wang, W.
PDB entry 4qp5: Catalytic domain of the antimicrobial peptidase lysostaphin from Staphylococcus simulans crystallized in the presence of phosphate
Classification: HYDROLASE
Source organism: Staphylococcus simulans bv. staphylolyticus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.26 Å
Deposited: 2014-06-22
Authors: Sabala, I., Jagielska, E., Bardelang, P.T., Czapinska, H., Dahms, S.O., Sharpe, J.A., James, R., Than, M.E., Thomas, N.R., Bochtler, M.
PDB entry 4qp6: Crystal Structure of ERK2 in complex with 5H-pyrrolo[2,3-b]pyrazine
Classification: transferase/transferase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1 Å
Deposited: 2014-06-22
Authors: Yin, J., Wang, W.
PDB entry 4qp7: Crystal Structure of ERK2 in complex with 2-(1H-pyrazol-4-yl)-5H-pyrrolo[2,3-b]pyrazine
Classification: transferase/transferase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.249 Å
Deposited: 2014-06-22
Authors: Yin, J., Wang, W.
PDB entry 4qp8: Crystal Structure of ERK2 in complex with 2-(1H-pyrazol-4-yl)-7-(pyridin-3-yl)-5H-pyrrolo[2,3-b]pyrazine
Classification: transferase/transferase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.446 Å
Deposited: 2014-06-22
Authors: Yin, J., Wang, W.
PDB entry 4qp9: Crystal Structure of ERK2 in complex with 7-(1-propyl-1H-pyrazol-4-yl)-2-(pyridin-4-yl)-5H-pyrrolo[2,3-b]pyrazine
Classification: transferase/transferase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.001 Å
Deposited: 2014-06-22
Authors: Yin, J., Wang, W.
PDB entry 4qpa: Crystal Structure of ERK2 in complex with 7-(1-benzyl-1H-pyrazol-4-yl)-2-(pyridin-4-yl)-5H-pyrrolo[2,3-b]pyrazine
Classification: transferase/transferase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.85 Å
Deposited: 2014-06-22
Authors: Yin, J., Wang, W.
PDB entry 4qpb: Catalytic domain of the antimicrobial peptidase lysostaphin from Staphylococcus simulans crystallized in the absence of phosphate
Classification: HYDROLASE
Source organism: Staphylococcus simulans
Experimental method: X-RAY DIFFRACTION
Resolution: 1.78 Å
Deposited: 2014-06-22
Authors: Sabala, I., Jagielska, E., Bardelang, P.T., Czapinska, H., Dahms, S.O., Sharpe, J.A., James, R., Than, M.E., Thomas, N.R., Bochtler, M.
PDB entry 4qpc: Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (Y200A) from zebrafish
Classification: OXIDOREDUCTASE
Source organism: Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 1.902 Å
Deposited: 2014-06-23
Authors: Lin, C.C., Chen, C.J., Fu, T.F., Chuankhayan, P., Kao, T.T., Chang, W.N.
PDB entry 4qpd: Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with tetrahydrofolate
Classification: OXIDOREDUCTASE
Source organism: Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2014-06-23
Authors: Lin, C.C., Chen, C.J., Fu, T.F., Chuankhayan, P., Kao, T.T., Chang, W.N.
PDB entry 4qpe: Crystal structure of Aminopeptidase N in complex with N-cyclohexyl-1,2-diaminoethylphosphonic acid
Classification: HYDROLASE
Source organism: Neisseria meningitidis MC58
Experimental method: X-RAY DIFFRACTION
Resolution: 2.004 Å
Deposited: 2014-06-23
Authors: Nocek, B., Mulligan, R., Berlicki, L., Vassilious, S., Mucha, A., Joachimiak, A.
PDB entry 4qpf: New lower bone affinity bisphosphonate drug design for effective use in diseases characterized by abnormal bone resorption
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.59 Å
Deposited: 2014-06-23
Authors: Ebetino, F.H., Lundy, M., Kwaasi, A.A., Dunford, J.E., Duan, Z., Triffitt, J., Mazur, A., Jeans, G., Barnett, B.L., Russell, R.G.G.
PDB entry 4qpg: Crystal structure of empty hepatitis A virus
Classification: VIRUS
Source organism: Human hepatitis A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.5 Å
Deposited: 2014-06-23
Authors: Wang, X., Ren, J., Gao, Q., Hu, Z., Sun, Y., Li, X., Rowlands, D.J., Yin, W., Wang, J., Stuart, D.I., Rao, Z., Fry, E.E.
PDB entry 4qpi: Crystal structure of hepatitis A virus
Classification: VIRUS
Source organism: Human hepatitis A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.01 Å
Deposited: 2014-06-23
Authors: Wang, X., Ren, J., Gao, Q., Hu, Z., Sun, Y., Li, X., Rowlands, D.J., Yin, W., Wang, J., Stuart, D.I., Rao, Z., Fry, E.E.
PDB entry 4qpj: 2.7 Angstrom Structure of a Phosphotransferase in Complex with a Receiver Domain
Classification: SIGNALING PROTEIN/DNA BINDING PROTEIN
Source organism: Brucella abortus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.742 Å
Deposited: 2014-06-23
Authors: Willett, J.W., Herrou, J., Crosson, S.
PDB entry 4qpk: 1.7 Angstrom Structure of a Bacterial Phosphotransferase
Classification: SIGNALING PROTEIN
Source organism: Brucella abortus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.66 Å
Deposited: 2014-06-23
Authors: Willett, J.W., Crosson, S., Herrou, J.
PDB entry 4qpl: Crystal structure of RNF146(RING-WWE)/UbcH5a/iso-ADPr complex
Classification: LIGASE
Source organism: Homo sapiens; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2014-06-23
Authors: Wang, Z., DaRosa, P.A., Klevit, R.E., Xu, W.
PDB entry 4qpm: Structure of Bub1 kinase domain
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.202 Å
Deposited: 2014-06-24
Authors: Lin, Z.H., Jia, L.Y., Tomchick, D.R., Luo, X.L., Yu, H.T.
PDB entry 4qpn: Crystal Structure of Human Methyltransferase-Like Protein 21B
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.25 Å
Deposited: 2014-06-24
Authors: Tempel, W., Hong, B.S., Seitova, A., He, H., Li, Y., Graslund, S., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Structural Genomics Consortium (SGC)
PDB entry 4qpo: Mechanistic basis of plasmid-specific DNA binding of the F plasmid regulatory protein, TraM
Classification: TRANSCRIPTION
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.999 Å
Deposited: 2014-06-24
Authors: Peng, Y., Lu, J., Wong, J., Edwards, R.A., Frost, L.S., Glover, J.N.M.
PDB entry 4qpp: The Crystal Structure of Human HMT1 hnRNP methyltransferase-like protein 6 in complex with compound DS-421 (2-{4-[3-CHLORO-2-(2-METHOXYPHENYL)-1H-INDOL-5-YL]PIPERIDIN-1-YL}-N-METHYLETHANAMINE
Classification: Transferase/transferase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.52 Å
Deposited: 2014-06-24
Authors: Dong, A., Zeng, H., Smil, D., Walker, J.R., He, H., Eram, M., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Vedadi, M., Brown, P.J., Wu, H., Structural Genomics Consortium (SGC)
PDB entry 4qpq: Mechanistic basis of plasmid-specific DNA binding of the F plasmid regulatory protein, TraM
Classification: TRANSCRIPTION/DNA
Source organism: Escherichia coli; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.106 Å
Deposited: 2014-06-24
Authors: Peng, Y., Lu, J., Wong, J., Edwards, R.A., Frost, L.S., Glover, J.N.M.
PDB entry 4qpr: CRYSTAL STRUCTURE OF GAF DOMAIN of POTASSIUM SENSOR HISTIDINE KINASE KDPD FROM ESCHERICHIA COLI
Classification: TRANSFERASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2014-06-24
Authors: Kumar, S., Yernool, D.A.
PDB entry 4qps: Crystal structure of Jak3 complexed to N-[3-(6-Phenylamino-pyrazin-2-yl)-3H-benzoimidazol-5-yl]-acrylamide
Classification: Transferase/transferase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2014-06-24
Authors: Argiriadi, M.A., Goedken, E.R.
PDB entry 4qpt: Structural Investigation of hnRNP L
Classification: RNA BINDING PROTEIN
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.351 Å
Deposited: 2014-06-25
Authors: Blatter, M., Allain, F.H.-T.
PDB entry 4qpv: Crystal structure of a DUF1672 family protein (SAV1486) from Staphylococcus aureus subsp. aureus Mu50 at 1.80 A resolution
Classification: STRUCTURAL GENOMICS, UNKNOWN FUNCTION
Source organism: Staphylococcus aureus subsp. aureus Mu50
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2014-06-25
Authors: Joint Center for Structural Genomics (JCSG)
PDB entry 4qpw: BiXyn10A CBM1 with Xylohexaose Bound
Classification: HYDROLASE
Source organism: Bacteroides intestinalis DSM 17393
Experimental method: X-RAY DIFFRACTION
Resolution: 1.14 Å
Deposited: 2014-06-25
Authors: Chekan, J.R., Nair, S.K.
PDB entry 4qpx: NV polymerase post-incorporation-like complex
Classification: Hydrolase/RNA
Source organism: Norwalk virus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.86 Å
Deposited: 2014-06-25
Authors: Zamyatkin, D.F., Parra, F., Grochulski, P., Ng, K.K.S.
PDB entry 4qpy: Crystal structure of C1QL2
Classification: PROTEIN BINDING
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.384 Å
Deposited: 2014-06-25
Authors: Ressl, S., Brunger, A.T.
PDB entry 4qpz: Crystal structure of the formolase FLS_v2 in space group P 21
Classification: LYASE
Source organism: Pseudomonas fluorescens
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2014-06-25
Authors: Shen, B.W., Siegel, J.B., Stoddard, B.L., Baker, D.
PDB entry 4qq0: CdsD - The structural protein of the Type III secretion system of Chlamydia trachomatis: C-terminal domain
Classification: STRUCTURAL PROTEIN
Source organism: Chlamydia trachomatis
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2014-06-26
Authors: Merilainen, G., Wierenga, R.K.
PDB entry 4qq1: Crystal structure of the isotype 1 Transferrin binding protein B (TbpB) from serogroup B Neisseria meningitidis
Classification: PROTEIN BINDING
Source organism: Neisseria meningitidis serogroup B
Experimental method: X-RAY DIFFRACTION
Resolution: 3.33 Å
Deposited: 2014-06-26
Authors: Calmettes, C., Moraes, T.F.
PDB entry 4qq2: Crystal structure of C1QL1
Classification: PROTEIN BINDING
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.801 Å
Deposited: 2014-06-26
Authors: Ressl, S., Brunger, A.T.
PDB entry 4qq3: Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, in complex with XMP
Classification: OXIDOREDUCTASE
Source organism: Vibrio cholerae O1 biovar El Tor str. N16961
Experimental method: X-RAY DIFFRACTION
Resolution: 1.72 Å
Deposited: 2014-06-26
Authors: Osipiuk, J., Maltseva, N., Makowska-Grzyska, M., Gu, M., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4qq4: CW-type zinc finger of MORC3 in complex with the amino terminus of histone H3
Classification: METAL BINDING PROTEIN
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2014-06-26
Authors: Liu, Y., Tempel, W., Dong, A., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
PDB entry 4qq5: Crystal Structure of FGF Receptor (FGFR) 4 Kinase Harboring the V550L Gate-Keeper Mutation in Complex With FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper Mutations
Classification: Transferase/transferase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.203 Å
Deposited: 2014-06-26
Authors: Huang, Z., Mohammadi, M.
PDB entry 4qq6: Crystal Structure of tudor domain of SMN1 in complex with a small organic molecule
Classification: RNA BINDING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2014-06-26
Authors: Liu, Y., Tempel, W., Iqbal, A., Walker, J.R., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Min, J., Structural Genomics Consortium (SGC)
PDB entry 4qq7: Crystal Structure of Putative stringent starvation protein A from Burkholderia cenocepacia with bound glutathione
Classification: TRANSFERASE
Source organism: Burkholderia cenocepacia
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2014-06-26
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 4qq8: Crystal structure of the formolase FLS in space group P 43 21 2
Classification: LYASE
Source organism: Pseudomonas fluorescens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.88 Å
Deposited: 2014-06-26
Authors: Shen, B.W., Siegel, J.B., Stoddard, B.L.
PDB entry 4qqa: Crystal structure of pneumolysin from Streptococcus pneumoniae
Classification: TOXIN
Source organism: Streptococcus pneumoniae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.802 Å
Deposited: 2014-06-27
Authors: Park, S.A., Lee, K.S.
PDB entry 4qqb: Structural basis for the assembly of the SXL-UNR translation regulatory complex
Classification: TRANLATION/RNA
Source organism: Drosophila melanogaster; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2014-06-27
Authors: Hennig, J., Popowicz, G.M., Sattler, M.
PDB entry 4qqc: Crystal Structure of FGF Receptor (FGFR) 4 Kinase Domain in Complex with FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper Mutations
Classification: Transferase/transferase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2014-06-27
Authors: Huang, Z., Mohammadi, M.
PDB entry 4qqd: Crystal Structure of tandem tudor domains of UHRF1 in complex with a small organic molecule
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.28 Å
Deposited: 2014-06-27
Authors: Liu, Y., Tempel, W., Iqbal, A., Walker, J.R., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Min, J., Structural Genomics Consortium (SGC)
PDB entry 4qqe: Crystal structure of WDR5, WD repeat domain 5 in complex with compound SGC-DS-MT-0345
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2014-06-27
Authors: Dong, A., Dombrovski, L., Wernimont, A., Smil, D., Getlik, M., Senisterra, G., Poda, G., Al-Awar, R., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Schapira, M., Vedadi, M., Wu, H., Structural Genomics Consortium (SGC)
PDB entry 4qqf: Crystal structure of mitochondrial import inner membrane translocase subunit TIM50
Classification: TRANSPORT PROTEIN
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.672 Å
Deposited: 2014-06-27
Authors: Li, J.Z.
PDB entry 4qqg: Crystal structure of an N-terminal HTATIP fragment
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2014-06-27
Authors: Liu, Y., Tempel, W., Wernimont, A.K., Dobrovetsky, E., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
PDB entry 4qqh: Crystal structure of C1QL3 in space group H32
Classification: PROTEIN BINDING
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.2 Å
Deposited: 2014-06-27
Authors: Ressl, S., Brunger, A.T.
PDB entry 4qqi: Crystal structure of ANKRA2-RFX7 complex
Classification: STRUCTURAL PROTEIN
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.03 Å
Deposited: 2014-06-27
Authors: Xu, C., Tempel, W., Dong, A., Mackenzie, F., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
PDB entry 4qqj: Crystal Structure of FGF Receptor (FGFR) 4 Kinase Domain Harboring the V550L Gate-Keeper Mutation
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.682 Å
Deposited: 2014-06-27
Authors: Huang, Z., Mohammadi, M.
PDB entry 4qqk: Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae) with GMS
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.88 Å
Deposited: 2014-06-27
Authors: Dong, A., Zeng, H., He, H., Wernimont, A., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Min, J., Luo, M., Wu, H., Structural Genomics Consortium (SGC)
PDB entry 4qql: Crystal structure of C1QL3 in P1 space group
Classification: PROTEIN BINDING
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.39 Å
Deposited: 2014-06-27
Authors: Ressl, S., Brunger, A.T.
PDB entry 4qqn: Protein arginine methyltransferase 3 in complex with compound MTV044246
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.08 Å
Deposited: 2014-06-27
Authors: Dong, A., Dobrovetsky, E., Tempel, W., He, H., Zhao, K., Smil, D., Landon, M., Luo, X., Chen, Z., Dai, M., Yu, Z., Lin, Y., Zhang, H., Zhao, K., Schapira, M., Brown, P.J., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Vedadi, M., Structural Genomics Consortium (SGC)
PDB entry 4qqo: Crystal structure of C1QL3 mutant D205A
Classification: PROTEIN BINDING
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.031 Å
Deposited: 2014-06-27
Authors: Ressl, S., Brunger, A.T.
PDB entry 4qqp: Crystal structure of C1QL3 mutant D207A
Classification: PROTEIN BINDING
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.464 Å
Deposited: 2014-06-27
Authors: Ressl, S., Brunger, A.T.
PDB entry 4qqq: Crystal structure of pneumolysin from Streptococcus pneumoniae, in complex with mannose as a component of cell membrane
Classification: TOXIN
Source organism: Streptococcus pneumoniae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2014-06-27
Authors: Park, S.A., Lee, K.S.
PDB entry 4qqr: Structural insight into nucleotide rhamnose synthase/epimerase-reductase from Arabidopsis thaliana
Classification: OXIDOREDUCTASE
Source organism: Arabidopsis thaliana
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2014-06-28
Authors: Han, X., Liu, X.
PDB entry 4qqs: Crystal structure of a thermostable family-43 glycoside hydrolase
Classification: HYDROLASE
Source organism: Halothermothrix orenii
Experimental method: X-RAY DIFFRACTION
Resolution: 1.1 Å
Deposited: 2014-06-29
Authors: Hassan, N., Kori, L.D., Patel, B.K.C., Divne, C., Tan, T.C.
PDB entry 4qqt: Crystal Structure of FGF Receptor (FGFR) 4 Tyrosine Kinase Domain
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.501 Å
Deposited: 2014-06-29
Authors: Huang, Z., Mohammadi, M.
PDB entry 4qqu: Crystal structure of the cobalamin-independent methionine synthase enzyme in a closed conformation
Classification: TRANSFERASE
Source organism: Candida albicans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.98 Å
Deposited: 2014-06-29
Authors: Ubhi, D.K., Robertus, J.D.
PDB entry 4qqv: Extracellular domains of mouse IL-3 beta receptor
Classification: SIGNALING PROTEIN
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.45 Å
Deposited: 2014-06-30
Authors: Jackson, C.J., Young, I.G., Murphy, J.M., Carr, P.D., Ewens, C.L., Dai, J., Ollis, D.L.
PDB entry 4qqw: Crystal structure of T. fusca Cas3
Classification: Hydrolase/DNA
Source organism: Thermobifida fusca; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.664 Å
Deposited: 2014-06-30
Authors: Ke, A., Huo, Y., Nam, K.H.
PDB entry 4qqx: Crystal structure of T. fusca Cas3-ATP
Classification: Hydrolase/dna
Source organism: Thermobifida fusca; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.34 Å
Deposited: 2014-06-30
Authors: Ke, A., Huo, Y., Nam, K.H.
PDB entry 4qqy: Crystal structure of T. fusca Cas3-ADP
Classification: Hydrolase/DNA
Source organism: Thermobifida fusca; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.12 Å
Deposited: 2014-06-30
Authors: Ke, A., Huo, Y., Nam, K.H.
PDB entry 4qqz: Crystal structure of T. fusca Cas3-AMPPNP
Classification: Hydrolase/DNA
Source organism: Thermobifida fusca; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.93 Å
Deposited: 2014-06-30
Authors: Ke, A., Huo, Y., Nam, K.H.
PDB entry 4qr0: Crystal structure of Streptococcus pyogenes Cas2 at pH 5.6
Classification: HYDROLASE
Source organism: Streptococcus pyogenes serotype M1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2014-06-30
Authors: Bae, E., Ka, D., Kim, D.
PDB entry 4qr1: Crystal structure of Streptococcus pyogenes Cas2 at pH 6.5
Classification: HYDROLASE
Source organism: Streptococcus pyogenes serotype M1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.193 Å
Deposited: 2014-06-30
Authors: Bae, E., Ka, D., Kim, D.
PDB entry 4qr2: Crystal structure of Streptococcus pyogenes Cas2 at pH 7.5
Classification: HYDROLASE
Source organism: Streptococcus pyogenes serotype M1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2014-06-30
Authors: Bae, E., Ka, D., Kim, D.
PDB entry 4qr3: Brd4 Bromodomain 1 complex with its novel inhibitors
Classification: TRANSCRIPTION/TRANSCRIPTION INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.374 Å
Deposited: 2014-06-30
Authors: Xiong, B., Cao, D.Y., Chen, T.T., Xu, Y.C.
PDB entry 4qr4: Brd4 Bromodomain 1 complex with its novel inhibitors
Classification: TRANSCRIPTION/TRANSCRIPTION INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.28 Å
Deposited: 2014-06-30
Authors: Xiong, B., Cao, D.Y., Chen, T.T., Xu, Y.C.
PDB entry 4qr5: Brd4 Bromodomain 1 complex with its novel inhibitors
Classification: TRANSCRIPTION/TRANSCRIPTION INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.41 Å
Deposited: 2014-06-30
Authors: Xiong, B., Cao, D.Y., Chen, T.T., Xu, Y.C.
PDB entry 4qr6: Human Aldose Reductase complexed with a ligand with an IDD structure (2-[2-(1,3-benzothiazol-2-ylmethylcarbamoyl)-5-fluoro-phenoxy]acetic acid) at 1.05 A
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.05 Å
Deposited: 2014-06-30
Authors: Rechlin, C., Heine, A., Klebe, G.
PDB entry 4qr7: Structure and specificity of L-D-Transpeptidase from Mycobacterium tuberculosis and antibiotic resistance: Calcium binding promotes dimer formation
Classification: HYDROLASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.303 Å
Deposited: 2014-06-30
Authors: Gokulan, K., Varughese, K.I.
PDB entry 4qr8: Crystal Structure of E coli pepQ
Classification: HYDROLASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.999 Å
Deposited: 2014-06-30
Authors: Pingwei, L.
PDB entry 4qr9: Crystal structure of two HMGB1 Box A domains cooperating to underwind and kink a DNA
Classification: DNA BINDING PROTEIN
Source organism: Rattus norvegicus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2014-06-30
Authors: Sanchez-Giraldo, R., Acosta-Reyes, F.J., Malarkey, C.S., Saperas, N., Churchill, M.E.A., Campos, J.L.
PDB entry 4qra: Structure and specificity of L-D-Transpeptidase from Mycobacterium tuberculosis and antibiotic resistance: Calcium binding promotes dimer formation
Classification: HYDROLASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.29 Å
Deposited: 2014-06-30
Authors: Gokulan, K., Varughese, K.I.
PDB entry 4qrb: Structure and specificity of L-D-Transpeptidase from Mycobacterium tuberculosis and antibiotic resistance: Calcium binding promotes dimer formation
Classification: HYDROLASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.64 Å
Deposited: 2014-06-30
Authors: Gokulan, K., Varughese, K.I.
PDB entry 4qrc: Crystal Structure of the Tyrosine Kinase Domain of FGF Receptor 4 in Complex with Ponatinib
Classification: Transferase/transferase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.901 Å
Deposited: 2014-06-30
Authors: Huang, Z., Mohammadi, M.
PDB entry 4qrd: Structure of Methionyl-tRNA Synthetase in complex with N-(1H-benzimidazol-2-ylmethyl)-N'-(2,4-dichlorophenyl)-6-(morpholin-4-yl)-1,3,5-triazine-2,4-diamine
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.97 Å
Deposited: 2014-06-30
Authors: Li, X., Hilgers, M.T., Stidham, M., Brown-Driver, V., Shaw, K.J., Finn, J.
PDB entry 4qre: Structure of Methionyl-tRNA Synthetase in complex with 1-(4-{4-[(1H-benzimidazol-2-ylmethyl)amino]-6-(4,5-dimethoxy-2-methylphenoxy)pyrimidin-2-yl}piperazin-1-yl)ethanone
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2014-06-30
Authors: Hilgers, M.T.
PDB entry 4qrf: Crystal structure of V30M mutant human transthyretin complexed with caffeic acid phenethyl ester
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2014-06-30
Authors: Yokoyama, T., Kosaka, Y., Mizuguchi, M.
PDB entry 4qrg: Crystal structure of I86L mutant of papain
Classification: HYDROLASE
Source organism: Carica papaya
Experimental method: X-RAY DIFFRACTION
Resolution: 2.497 Å
Deposited: 2014-07-01
Authors: Dutta, S., Choudhury, D., Roy, S., Biswas, S.
PDB entry 4qrh: Molecular mechanism and evolution of guanylate kinase regulation by (p)ppGpp
Classification: TRANSFERASE
Source organism: Staphylococcus aureus USA300-ISMMS1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2014-07-01
Authors: Liu, K., Krasny, K., Myers, A.R., Satyshur, K.A., Keck, J.L., Wnag, J.D.
PDB entry 4qri: 2.35 Angstrom resolution crystal structure of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130
Classification: TRANSFERASE
Source organism: Leptospira interrogans serovar Copenhageni
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2014-07-01
Authors: Halavaty, A.S., Minasov, G., Dubrovska, I., Flores, K.J., Shuvalova, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4qrj: Crystal structure of a putative 6-phosphogluconolactonase (BACUNI_04672) from Bacteroides uniformis ATCC 8492 at 2.20 A resolution
Classification: HYDROLASE
Source organism: Bacteroides uniformis ATCC 8492
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2014-07-01
Authors: Joint Center for Structural Genomics (JCSG)
PDB entry 4qrk: Crystal structure of a putative cell adhesion protein (CLOSPO_03726) from Clostridium sporogenes ATCC 15579 at 1.95 A resolution
Classification: CELL ADHESION
Source organism: Clostridium sporogenes ATCC 15579
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2014-07-01
Authors: Joint Center for Structural Genomics (JCSG)
PDB entry 4qrl: Crystal structure of a lipocalin-like protein (BACUNI_01346) from Bacteroides uniformis ATCC 8492 at 1.79 A resolution
Classification: STRUCTURAL GENOMICS, UNKNOWN FUNCTION
Source organism: Bacteroides uniformis ATCC 8492
Experimental method: X-RAY DIFFRACTION
Resolution: 1.79 Å
Deposited: 2014-07-01
Authors: Joint Center for Structural Genomics (JCSG)
PDB entry 4qrm: crystal structure of a binary complex of FliM-FliG middle domains from T.maritima
Classification: PROTEIN BINDING
Source organism: Thermotoga maritima
Experimental method: X-RAY DIFFRACTION
Resolution: 4.315 Å
Deposited: 2014-07-01
Authors: Crane, B.R., Sircar, R.
PDB entry 4qrn: HIGH-RESOLUTION CRYSTAL STRUCTURE of 5-CARBOXYVANILLATE DECARBOXYLASE (TARGET EFI-505250) FROM NOVOSPHINGOBIUM AROMATICIVORANS DSM 12444 COMPLEXED WITH MANGANESE AND 4-HYDROXY-3-METHOXY-5-NITROBENZOIC ACID
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Novosphingobium aromaticivorans
Experimental method: X-RAY DIFFRACTION
Resolution: 1.07 Å
Deposited: 2014-07-01
Authors: Patskovsky, Y., Vladimirova, A., Toro, R., Bhosle, R., Gerlt, J.A., Raushel, F.M., Almo, S.C.
PDB entry 4qro: CRYSTAL STRUCTURE of DIHYDROXYBENZOIC ACID DECARBBOXYLASE BPRO_2061 (TARGET EFI-500288) FROM POLAROMONAS SP. JS666 WITH BOUND MANGANESE AND AN INHIBITOR, 2-NITRORESORCINOL
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Polaromonas
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2014-07-01
Authors: Patskovsky, Y., Vladimirova, A., Toro, R., Bhosle, R., Gerlt, J.A., Raushel, M., Almo, S.C.
PDB entry 4qrp: Crystal Structure of HLA B*0801 in complex with HSKKKCDEL and DD31 TCR
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2014-07-02
Authors: Gras, S., Berry, R., Lucet, I.S., Rossjohn, J.
PDB entry 4qrq: Crystal Structure of HLA B*0801 in complex with HSKKKCDEL
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2014-07-02
Authors: Gras, S., Berry, R., Lucet, I.S., Rossjohn, J.
PDB entry 4qrr: Crystal Structure of HLA B*3501-IPS in complex with a Delta-Beta TCR, clone 12 TCR
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2014-07-02
Authors: Gras, S., Chabrol, E., Rossjohn, J.
PDB entry 4qrs: Crystal Structure of HLA B*0801 in complex with ELK_IYM, ELKRKMIYM
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2014-07-02
Authors: Gras, S., Twist, K.-A., Rossjohn, J.
PDB entry 4qrt: Crystal Structure of HLA B*0801 in complex with ELN_YYM, ELNRKMIYM
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2014-07-02
Authors: Gras, S., Twist, K.-A., Rossjohn, J.
PDB entry 4qru: Crystal Structure of HLA B*0801 in complex with ELR_MYM, ELRRKMMYM
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2014-07-02
Authors: Gras, S., Twist, K.-A., Rossjohn, J.
PDB entry 4qrv: Crystal structure of I86F mutant of papain
Classification: HYDROLASE
Source organism: Carica papaya
Experimental method: X-RAY DIFFRACTION
Resolution: 1.978 Å
Deposited: 2014-07-02
Authors: Dutta, S., Choudhury, D., Roy, S.
PDB entry 4qrx: Crystal structure of pro-papain mutant at pH 4.0
Classification: HYDROLASE
Source organism: Carica papaya
Experimental method: X-RAY DIFFRACTION
Resolution: 3.138 Å
Deposited: 2014-07-02
Authors: Dutta, S., Choudhury, D., Roy, S., Biswas, S.
PDB entry 4qry: the ground state and the N intermediate of pharaonis halorhodopsin in complex with bromide ion
Classification: MEMBRANE PROTEIN
Source organism: Natronomonas pharaonis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2014-07-02
Authors: Kouyama, T., Kawaguchi, H.
PDB entry 4qrz: Crystal structure of sugar transporter atu4361 from agrobacterium fabrum c58, target efi-510558, with bound maltotriose
Classification: TRANSPORT PROTEIN
Source organism: AGROBACTERIUM FABRUM
Experimental method: X-RAY DIFFRACTION
Resolution: 1.34 Å
Deposited: 2014-07-02
Authors: Patskovsky, Y., Toro, R., Bhosle, R., Al Obaidi, N., Stead, M., Washington, E., Glenn, A.S., Chowdhury, S., Evans, B., Hammonds, J., Love, J., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4qs4: Crystal Structure of CofB from Enterotoxigenic Escherichia coli
Classification: CELL ADHESION
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2014-07-02
Authors: Kolappan, S., Craig, L.
PDB entry 4qs5: CRYSTAL STRUCTURE of 5-CARBOXYVANILLATE DECARBOXYLASE LIGW2 FROM NOVOSPHINGOBIUM AROMATICIVORANS DSM 12444 (TARGET EFI-505250) WITH BOUND MANGANESE AND 3-methoxy-4-hydroxy-5-nitrobenzoic acid, THE D314N MUTANT
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Novosphingobium aromaticivorans
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2014-07-02
Authors: Patskovsky, Y., Vladimirova, A., Toro, R., Bhosle, R., Hillerich, B., Seidel, R.D., Raushel, M., Almo, S.C.
PDB entry 4qs6: CRYSTAL STRUCTURE of 5-CARBOXYVANILLATE DECARBOXYLASE LIGW2 FROM NOVOSPHINGOBIUM AROMATICIVORANS DSM 12444 (TARGET EFI-505250) WITH BOUND 4-HYDROXY-3-METHOXY-5-NITROBENZOIC ACID, NO METAL, THE D314N MUTANT
Classification: HYDROLASE
Source organism: Novosphingobium aromaticivorans
Experimental method: X-RAY DIFFRACTION
Resolution: 1.76 Å
Deposited: 2014-07-03
Authors: Patskovsky, Y., Vladimirova, A., Toro, R., Bhosle, R., Gerlt, J.A., Raushel, F.M., Almo, S.C.
PDB entry 4qs7: Arabidopsis Hexokinase 1 (AtHXK1) structure in glucose-bound form
Classification: TRANSFERASE
Source organism: Arabidopsis thaliana
Experimental method: X-RAY DIFFRACTION
Resolution: 2.001 Å
Deposited: 2014-07-03
Authors: Feng, J., Zhao, S., Liu, L.
PDB entry 4qs8: Arabidopsis Hexokinase 1 (AtHXK1) structure in ligand-free form
Classification: TRANSFERASE
Source organism: Arabidopsis thaliana
Experimental method: X-RAY DIFFRACTION
Resolution: 1.798 Å
Deposited: 2014-07-03
Authors: Feng, J., Zhao, S., Liu, L.
PDB entry 4qs9: Arabidopsis Hexokinase 1 (AtHXK1) mutant S177A structure in glucose-bound form
Classification: TRANSFERASE
Source organism: Arabidopsis thaliana
Experimental method: X-RAY DIFFRACTION
Resolution: 2.103 Å
Deposited: 2014-07-03
Authors: Feng, J., Zhao, S., Liu, L.
PDB entry 4qsa: Crystal structure of human carbonic anhydrase isozyme II with 2-chloro-4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}benzenesulfonamide
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.501 Å
Deposited: 2014-07-03
Authors: Smirnov, A., Manakova, E., Grazulis, S.
PDB entry 4qsb: Crystal structure of human carbonic anhydrase isozyme II with 3-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}benzenesulfonamide
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2014-07-03
Authors: Smirnov, A., Manakova, E., Grazulis, S.
PDB entry 4qsc: Crystal structure of ATU4361 sugar transporter from Agrobacterium Fabrum C58, target efi-510558, with bound maltose
Classification: TRANSPORT PROTEIN
Source organism: AGROBACTERIUM FABRUM
Experimental method: X-RAY DIFFRACTION
Resolution: 1.3 Å
Deposited: 2014-07-03
Authors: Patskovsky, Y., Toro, R., Bhosle, R., Al Obaidi, N., Chamala, S., Attonito, J.D., Scott Glenn, A., Chowdhury, S., Lafleur, J., Siedel, R.D., Hillerich, B., Love, J., Whalen, K.L., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4qsd: Crystal structure of atu4361 sugar transporter from Agrobacterium Fabrum C58, target efi-510558, with bound sucrose
Classification: TRANSPORT PROTEIN
Source organism: AGROBACTERIUM FABRUM
Experimental method: X-RAY DIFFRACTION
Resolution: 1.34 Å
Deposited: 2014-07-03
Authors: Patskovsky, Y., Toro, R., Bhosle, R., Al Obaidi, N., Chamala, S., Attonito, J.D., Scott Glenn, A., Chowdhury, S., Lafleur, J., Siedel, R.D., Hillerich, B., Love, J., Whalen, K.L., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4qse: Crystal structure of ATU4361 sugar transporter from Agrobacterium Fabrum c58, target efi-510558, with bound glycerol
Classification: TRANSPORT PROTEIN
Source organism: AGROBACTERIUM FABRUM
Experimental method: X-RAY DIFFRACTION
Resolution: 1.37 Å
Deposited: 2014-07-03
Authors: Patskovsky, Y., Toro, R., Bhosle, R., Al Obaidi, N., Chamala, S., Attonito, K.L., Scott Glenn, A., Chowdhury, S., Lafleur, J., Siedel, R.D., Hillerich, B., Love, J., Whalen, K.L., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4qsf: CRYSTAL STRUCTURE of AMIDOHYDROLASE PMI1525 (TARGET EFI-500319) FROM PROTEUS MIRABILIS HI4320, A COMPLEX WITH BUTYRIC ACID AND MANGANESE
Classification: HYDROLASE
Source organism: Proteus mirabilis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2014-07-03
Authors: Patskovsky, Y., Toro, R., Xiang, D.F., Raushel, F.M., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4qsg: Crystal structure of gas vesicle protein GvpF from Microcystis aeruginosa
Classification: STRUCTURAL PROTEIN
Source organism: Microcystis aeruginosa PCC 7806
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2014-07-03
Authors: Xu, B.Y., Dai, Y.N., Zhou, K., Ren, Y.M., Liu, Y.T., Chen, Y., Zhou, C.Z.
PDB entry 4qsh: Crystal Structure of L. monocytogenes Pyruvate Carboxylase in complex with Cyclic-di-AMP
Classification: LIGASE
Source organism: Listeria monocytogenes
Experimental method: X-RAY DIFFRACTION
Resolution: 2.51 Å
Deposited: 2014-07-04
Authors: Choi, P.H., Tong, L.
PDB entry 4qsi: Crystal structure of human carbonic anhydrase isozyme II with 5-{[(4-tert-buthyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}-2-chlorobenzenesulfonamide
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2014-07-04
Authors: Manakova, E., Smirnov, A., Grazulis, S.
PDB entry 4qsj: Crystal structure of human carbonic anhydrase isozyme XIII with 2-chloro-4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}benzenesulfonamide
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2014-07-04
Authors: Smirnov, A., Manakova, E., Grazulis, S.
PDB entry 4qsk: Crystal Structure of L. monocytogenes Pyruvate Carboxylase in complex with Cyclic-di-AMP
Classification: LIGASE
Source organism: Listeria monocytogenes
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2014-07-04
Authors: Choi, P.H., Tong, L.
PDB entry 4qsl: Crystal Structure of Listeria Monocytogenes Pyruvate Carboxylase
Classification: LIGASE
Source organism: Listeria monocytogenes
Experimental method: X-RAY DIFFRACTION
Resolution: 3.28 Å
Deposited: 2014-07-04
Authors: Choi, P.H., Tong, L.
PDB entry 4qsm: Crystal structure of human muscle L-lactate dehydrogenase in complex with inhibitor 2, 3-{[7-(2,4-dimethoxypyrimidin-5-yl)-3-sulfamoylquinolin-4-yl]amino}benzoic acid
Classification: oxidoreductase/oxidoreductase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2014-07-06
Authors: Kolappan, S., Craig, L.
PDB entry 4qsp: Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with acetyl-lysine
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2014-07-06
Authors: Chaikuad, A., Felletar, I., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
PDB entry 4qsq: Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) with bound DMSO
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2014-07-06
Authors: Chaikuad, A., Felletar, I., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
PDB entry 4qsr: Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) with bound MPD
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2014-07-06
Authors: Chaikuad, A., Felletar, I., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
PDB entry 4qss: Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with N-Methyl-2-pyrrolidone (NMP)
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2014-07-06
Authors: Chaikuad, A., Felletar, I., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
PDB entry 4qst: Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with 1-methylquinolin 2-one
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2014-07-06
Authors: Chaikuad, A., Felletar, I., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
PDB entry 4qsu: Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with thymine
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2014-07-06
Authors: Chaikuad, A., Felletar, I., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
PDB entry 4qsv: Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with thymidine
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2014-07-06
Authors: Chaikuad, A., Felletar, I., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
PDB entry 4qsw: Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with 5-methyl uridine
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2014-07-06
Authors: Chaikuad, A., Felletar, I., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
PDB entry 4qsx: Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with 3'-deoxy thymidine
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.93 Å
Deposited: 2014-07-06
Authors: Chaikuad, A., Felletar, I., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
PDB entry 4qsy: SHP2 SH2 domain in complex with GAB1 peptide
Classification: HYDROLASE/PROTEIN BINDING
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2014-07-06
Authors: Gogl, G., Remenyi, A.
PDB entry 4qsz: Crystal structure of mouse JMJd7 fused with maltose-binding protein
Classification: TRANSCRIPTION
Source organism: Escherichia coli K-12; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.86 Å
Deposited: 2014-07-06
Authors: Liu, H., Wang, C., Zhang, G.Y.
PDB entry 4qt0: Crystal structure of human muscle L-lactate dehydrogenase in complex with inhibitor 1, 3-{[3-CARBAMOYL-7-(2,4-DIMETHOXYPYRIMIDIN-5-YL)QUINOLIN-4-YL]AMINO}BENZOIC ACID
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2 Å
Deposited: 2014-07-06
Authors: Kolappan, S., Craig, L.