LiteFold/PDB huggingface dataset:
PDB entry 5v7q: Cryo-EM structure of the large ribosomal subunit from Mycobacterium tuberculosis bound with a potent linezolid analog
Classification: RIBOSOME
Source organism: Mycobacterium tuberculosis
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.7 Å
Deposited: 2017-03-20
Authors: Yang, K., Chang, J.-Y., Cui, Z., Zhang, J.
PDB entry 5v7r: Cyrstal structure of anti-Tau antibody CBTAU-7.1 Fab
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2017-03-20
Authors: Zhu, X., Zhang, H., Wilson, I.A.
PDB entry 5v7s: Crystal structure of Influenza A virus matrix protein M1 (NLS-88E, pH 6.2)
Classification: VIRAL PROTEIN
Source organism: Influenza A virus (strain A/Wilson-Smith/1933 H1N1)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2017-03-20
Authors: Musayev, F.N., Safo, M.K., Althufairi, B., Desai, U.R., Xie, H., Mosier, P.D., Chiang, M.-J., Zhou, Q.
PDB entry 5v7t: crystal structure of PARP14 bound to N-{4-[4-(diphenylmethoxy)piperidin-1-yl]butyl}[1,2,4]triazolo[4,3-b]pyridazin-6-amine inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2017-03-20
Authors: saikatendu, k.s., Hirozane, M.
PDB entry 5v7u: Cyrstal structure of anti-Tau antibody CBTAU-22.1 Fab
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.64 Å
Deposited: 2017-03-20
Authors: Zhu, X., Zhang, H., Wilson, I.A.
PDB entry 5v7v: Cryo-EM structure of ERAD-associated E3 ubiquitin-protein ligase component HRD3
Classification: PROTEIN TRANSPORT
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.9 Å
Deposited: 2017-03-20
Authors: Mi, W., Schoebel, S., Stein, A., Rapoport, T.A., Liao, M.
PDB entry 5v7w: Crystal structure of human PARP14 bound to 2-{[(1-methylpiperidin-4-yl)methyl]amino}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.65 Å
Deposited: 2017-03-20
Authors: saikatendu, k.s., Hirozane, M.
PDB entry 5v7x: Crystal Structure of Myosin 1b residues 1-728 with bound sulfate and Calmodulin
Classification: MOTOR PROTEIN
Source organism: Homo sapiens; Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.141 Å
Deposited: 2017-03-20
Authors: Zwolak, A., Shuman, H., Dominguez, R., Ostap, E.M.
PDB entry 5v7y: Prolyl 4-Hydroxylase Interacts with and Modifies Elongation Factor Tu
Classification: OXIDOREDUCTASE
Source organism: Bacillus anthracis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2017-03-21
Authors: Schnicker, N.J., Dey, M.
PDB entry 5v7z: SSNMR Structure of the Human RIP1/RIP3 Necrosome
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: SOLID-STATE NMR
Deposited: 2017-03-21
Authors: Mompean, M., Li, W., Li, J., Laage, S., Siemer, A.B., Wu, H., McDermott, A.E.
PDB entry 5v80: PIM1 kinase in complex with Cpd1 (1-methyl-4-(3-(6-(piperazin-1-yl)pyridin-2-yl)-1H-pyrazolo[3,4-c]pyridin-5-yl)piperazin-2-one)
Classification: TRANSFERASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.252 Å
Deposited: 2017-03-21
Authors: Murray, J.M., Wallweber, H.
PDB entry 5v82: PIM1 kinase in complex with Cpd17 (1-(6-(4,4-difluoropiperidin-3-yl)pyridin-2-yl)-6-(6-methylpyrazin-2-yl)-1H-pyrazolo[4,3-c]pyridine)
Classification: TRANSFERASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.888 Å
Deposited: 2017-03-21
Authors: Murray, J.M., Wallweber, H.
PDB entry 5v83: Structure of DCN1 bound to NAcM-HIT
Classification: LIGASE
Source organism: Enterobacteria phage T4; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.002 Å
Deposited: 2017-03-21
Authors: Guy, R.K., Schulman, B.A., Scott, D.C., Hammill, J.T.
PDB entry 5v84: CECR2 in complex with Cpd6 (6-allyl-N,2-dimethyl-7-oxo-N-(1-(1-phenylethyl)piperidin-4-yl)-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-4-carboxamide)
Classification: Transcription/Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2017-03-21
Authors: Murray, J.M., Kiefer, J.R., Jayaran, H., Bellon, S., Boy, F.
PDB entry 5v85: The crystal structure of the protein of DegV family COG1307 from Ruminococcus gnavus ATCC 29149 (alternative refinement of PDB 3JR7 with Vaccenic acid)
Classification: TRANSPORT PROTEIN
Source organism: Ruminococcus gnavus ATCC 29149
Experimental method: X-RAY DIFFRACTION
Resolution: 2.003 Å
Deposited: 2017-03-21
Authors: Cuypers, M.G., Ericson, M., subramanian, C., White, S.W., Rock, C.O.
PDB entry 5v86: Structure of DCN1 bound to NAcM-OPT
Classification: HYDROLASE
Source organism: Enterobacteria phage T4; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.374 Å
Deposited: 2017-03-21
Authors: Guy, R.K., Schulman, B.A., Scott, D.C., Hammill, J.T.
PDB entry 5v87: Crystal structure of LARP1-unique domain DM15 bound to m7GpppC
Classification: RNA BINDING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.692 Å
Deposited: 2017-03-21
Authors: Berman, A.J., Lahr, R.M.
PDB entry 5v88: Structure of DCN1 bound to NAcM-COV
Classification: Ligase / protein binding
Source organism: Enterobacteria phage T4; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.601 Å
Deposited: 2017-03-21
Authors: Guy, R.K., Schulman, B.A., Scott, D.C., Hammill, J.T.
PDB entry 5v89: Structure of DCN4 PONY domain bound to CUL1 WHB
Classification: Ligase / protein binding
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2017-03-21
Authors: Guy, R.K., Schulman, B.A., Scott, D.C., Hammill, J.T.
PDB entry 5v8a: Crystal structure of Influenza A virus matrix protein M1 (NLS-88R, pH 7.3)
Classification: VIRAL PROTEIN
Source organism: Influenza A virus (strain A/Wilson-Smith/1933 H1N1)
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2017-03-21
Authors: Musayev, F.N., Safo, M.K., Desai, U.R., Xie, H., Mosier, P.D., Zhou, Q., Chiang, M.-J., Kosikova, M.
PDB entry 5v8c: LytR-Csp2A-Psr enzyme from Actinomyces oris
Classification: TRANSCRIPTION
Source organism: Actinomyces oris
Experimental method: X-RAY DIFFRACTION
Resolution: 2.51 Å
Deposited: 2017-03-21
Authors: Amer, B.R., Sawaya, M.R., Liauw, B., Fu, J.Y., Ton-That, H., Clubb, R.T.
PDB entry 5v8d: Structure of Bacillus cereus PatB1 with sulfonyl adduct
Classification: TRANSFERASE
Source organism: Bacillus cereus (strain ATCC 10987 / NRS 248)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.001 Å
Deposited: 2017-03-21
Authors: Sychantha, D., Little, D.J., Chapman, R.N., Boons, G.J., Robinson, H., Howell, P.L., Clarke, A.J.
PDB entry 5v8e: Structure of Bacillus cereus PatB1
Classification: UNKNOWN FUNCTION
Source organism: Bacillus cereus (strain ATCC 10987 / NRS 248)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2017-03-21
Authors: Sychantha, D., Little, D.J., Chapman, R.N., Boons, G.J., Robinson, H., Howell, P.L., Clarke, A.J.
PDB entry 5v8f: Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1
Classification: REPLICATION
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.9 Å
Deposited: 2017-03-21
Authors: Yuan, Z., Riera, A., Bai, L., Sun, J., Spanos, C., Chen, Z.A., Barbon, M., Rappsilber, J., Stillman, B., Speck, C., Li, H.
PDB entry 5v8g: Pekin duck lysozyme isoform I (DEL-I)
Classification: HYDROLASE
Source organism: Anas platyrhynchos
Experimental method: X-RAY DIFFRACTION
Resolution: 1.2 Å
Deposited: 2017-03-22
Authors: Langley, D.B., Christ, D.
PDB entry 5v8i: Thermus thermophilus 70S ribosome lacking ribosomal protein uS17
Classification: RIBOSOME
Source organism: Escherichia coli (strain K12); Thermus parvatiensis (strain HB27 / ATCC BAA-163 / DSM 7039); Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039); Thermus thermophilus (strain HB27/ATCC BAA-163 / DSM 7039); Thermus thermophilus HB27
Experimental method: X-RAY DIFFRACTION
Resolution: 3.25 Å
Deposited: 2017-03-22
Authors: Gregory, S.T., Jogl, G.
PDB entry 5v8k: Homodimeric reaction center of H. modesticaldum
Classification: PHOTOSYNTHESIS
Source organism: Heliobacterium modesticaldum; Heliobacterium modesticaldum (strain ATCC 51547 / Ice1)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2017-03-22
Authors: Gisriel, C., Sarrou, I., Ferlez, B., Golbeck, J., Redding, K.E., Fromme, R.
PDB entry 5v8l: BG505 SOSIP.664 trimer in complex with broadly neutralizing HIV antibodies 3BNC117 and PGT145
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Human immunodeficiency virus 1
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.3 Å
Deposited: 2017-03-22
Authors: Lee, J.H., Ward, A.B.
PDB entry 5v8m: BG505 SOSIP.664 trimer in complex with broadly neutralizing HIV antibody 3BNC117
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Human immunodeficiency virus 1
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.4 Å
Deposited: 2017-03-22
Authors: Lee, J.H., Cottrell, C.A., Ward, A.B.
PDB entry 5v8o: Discovery of a high affinity inhibitor of cGAS
Classification: transferase/transferase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1 Å
Deposited: 2017-03-22
Authors: Hall, J.
PDB entry 5v8p: Small Molecule Inhibitor ABS-143 Bound to the Botulinum Neurotoxin Serotype A Light Chain
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Clostridium botulinum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.501 Å
Deposited: 2017-03-22
Authors: Allen, K.N., Silvaggi, N.R.
PDB entry 5v8q: Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs): Part III
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.44 Å
Deposited: 2017-03-22
Authors: Wilson, K.P.
PDB entry 5v8r: Small Molecule Inhibitor ABS-143 Bound to the Botulinum Neurotoxin Serotype A Light Chain
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Clostridium botulinum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2017-03-22
Authors: Allen, K.N., Silvaggi, N.R.
PDB entry 5v8s: Flavo di-iron protein H90D mutant from Thermotoga maritima
Classification: ELECTRON TRANSPORT
Source organism: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.41 Å
Deposited: 2017-03-22
Authors: Taylor, A.B., Becker, A., Giri, N., Hart, P.J., Kurtz Jr., D.M.
PDB entry 5v8t: Crystal structure of SMT fusion Peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with SF354
Classification: ISOMERASE
Source organism: Burkholderia pseudomallei; Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2017-03-22
Authors: Lorimer, D.D., Dranow, D.M., Seufert, F., Abendroth, J., Holzgrabe, U.
PDB entry 5v8u: Small Molecule Inhibitor ABS-143 Bound to the Botulinum Neurotoxin Serotype A Light Chain
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Clostridium botulinum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2017-03-22
Authors: Allen, K.N., Silvaggi, N.R.
PDB entry 5v8v: Crystal Structure of Human Renin in Complex with a biphenylpipderidinylcarbinol
Classification: HYDROLASE/HYDROLASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2017-03-22
Authors: Concha, N., Zhao, B.
PDB entry 5v8w: Crystal structure of human Integrator IntS9-IntS11 CTD complex
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2017-03-22
Authors: Wu, Y., Tong, L.
PDB entry 5v8x: Mutant Structures of Streptococcus Agalactiae GBS Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)
Classification: OXIDOREDUCTASE
Source organism: Streptococcus agalactiae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.95 Å
Deposited: 2017-03-22
Authors: Schormann, N., Ulett, G.C., Chattopadhyay, D.
PDB entry 5v8y: Mutant Structures of Streptococcus Agalactiae GBS Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)
Classification: OXIDOREDUCTASE
Source organism: Streptococcus agalactiae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2017-03-22
Authors: Schormann, N., Ulett, G.C., Chattopadhyay, D.
PDB entry 5v8z: Crystal structure of ERp29 D-domain in complex with the P-domain of calmegin
Classification: CHAPERONE
Source organism: Canis lupus familiaris; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.105 Å
Deposited: 2017-03-22
Authors: Kozlov, G., Munoz-Escobar, J., Gehring, K.
PDB entry 5v90: Crystal structure of ERp29 D-domain in complex with the P-domain of calreticulin
Classification: CHAPERONE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.255 Å
Deposited: 2017-03-22
Authors: Kozlov, G., Munoz-Escobar, J., Gehring, K.
PDB entry 5v91: Crystal structure of fosfomycin resistance protein from Klebsiella pneumoniae
Classification: TRANSFERASE
Source organism: Klebsiella pneumoniae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.3 Å
Deposited: 2017-03-22
Authors: Klontz, E., Guenther, S., Silverstein, Z., Sundberg, E.
PDB entry 5v92: Pekin duck egg lysozyme isoform III (DEL-III), orthorhombic form
Classification: HYDROLASE
Source organism: Anas platyrhynchos
Experimental method: X-RAY DIFFRACTION
Resolution: 1.11 Å
Deposited: 2017-03-22
Authors: Langley, D.B., Christ, D.
PDB entry 5v93: Cryo-EM structure of the 70S ribosome from Mycobacterium tuberculosis bound with Capreomycin
Classification: RIBOSOME
Source organism: Mycobacterium tuberculosis; Streptomyces puniceus
Experimental method: ELECTRON MICROSCOPY
Resolution: 4 Å
Deposited: 2017-03-22
Authors: Yang, K., Chang, J.-Y., Cui, Z., Li, X., Meng, R., Duan, L., Thongchol, J., Jakana, J., Huwe, C., Sacchettini, J., Zhang, J.
PDB entry 5v94: Pekin duck egg lysozyme isoform III (DEL-III), cubic form
Classification: HYDROLASE
Source organism: Anas platyrhynchos
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2017-03-22
Authors: Langley, D.B., Christ, D.
PDB entry 5v95: Structure of the H477R variant of rat cytosolic PEPCK in complex with manganese.
Classification: LYASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2017-03-23
Authors: Holyoak, T., Cui, D.S.
PDB entry 5v96: Crystal Structure of S-adenosyl-l-homocysteine Hydrolase from Naegleria fowleri with bound NAD and Adenosine
Classification: HYDROLASE
Source organism: Naegleria fowleri
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2017-03-23
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5v97: Structure of the H477R variant of rat cytosolic PEPCK in complex with GTP.
Classification: LYASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2017-03-23
Authors: Holyoak, T., Cui, D.S.
PDB entry 5v9f: Structure of the H477R variant of rat cytosolic PEPCK in complex with beta sulfopyruvate and GTP.
Classification: LYASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2017-03-23
Authors: Holyoak, T., Cui, D.S.
PDB entry 5v9g: Structure of the H477R variant of rat cytosolic PEPCK in complex with oxalate and GTP.
Classification: LYASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2017-03-23
Authors: Holyoak, T., Cui, D.S.
PDB entry 5v9h: Structure of the H477R variant of rat cytosolic PEPCK in complex with phosphoglycolate and GDP.
Classification: LYASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2017-03-23
Authors: Holyoak, T., Cui, D.S.
PDB entry 5v9i: Crystal structure of catalytic domain of G9a with MS0105
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.74 Å
Deposited: 2017-03-23
Authors: Dong, A., Zeng, H., Liu, J., Xiong, Y., Babault, N., Jin, J., Walker, J.R., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Wu, H., Brown, P.J., Structural Genomics Consortium (SGC)
PDB entry 5v9j: Crystal structure of catalytic domain of GLP with MS0105
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.74 Å
Deposited: 2017-03-23
Authors: Dong, A., Zeng, H., Liu, J., Xiong, Y., Babault, N., Jin, J., Tempel, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Wu, H., Brown, P.J., Structural Genomics Consortium (SGC)
PDB entry 5v9l: KRAS G12C in bound to quinazoline based switch II pocket (SWIIP) binder
Classification: HYDROLASE/HYDROLASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.981 Å
Deposited: 2017-03-23
Authors: Westover, K., Lu, J.
PDB entry 5v9o: KRAS G12C inhibitor
Classification: HYDROLASE/HYDROLASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.56 Å
Deposited: 2017-03-23
Authors: Westover, K., Lu, J.
PDB entry 5v9p: Crystal structure of pyrrolidine amide inhibitor [(3S)-3-(4-bromo-1H-pyrazol-1-yl)pyrrolidin-1-yl][3-(propan-2-yl)-1H-pyrazol-5-yl]methanone (compound 35) in complex with KDM5A
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2017-03-23
Authors: Kiefer, J.R., Liang, J., Vinogradova, M.
PDB entry 5v9t: Crystal structure of selective pyrrolidine amide KDM5a inhibitor N-{(3R)-1-[3-(propan-2-yl)-1H-pyrazole-5-carbonyl]pyrrolidin-3-yl}cyclopropanecarboxamide (compound 48)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.05 Å
Deposited: 2017-03-23
Authors: Kiefer, J.R., Liang, J., Vinogradova, M.
PDB entry 5v9u: Crystal Structure of small molecule ARS-1620 covalently bound to K-Ras G12C
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.38 Å
Deposited: 2017-03-23
Authors: Janes, M.R., Zhang, J., Li, L.-S., Hansen, R., Peters, U., Guo, X., Chen, Y., Babbar, A., Firdaus, S.J., Feng, J., Chen, J.H., Li, S., Brehmer, D., Darjania, L., Li, S., Long, Y.O., Thach, C., Liu, Y., Zarieh, A., Ely, T., Kucharski, J.M., Kessler, L.V., Wu, T., Wang, Y., Yao, Y., Deng, X., Zarrinkar, P., Dashyant, D., Lorenzi, M.V., Hu-Lowe, D., Patricelli, M.P., Ren, P., Liu, Y.
PDB entry 5v9x: Structure of Mycobacterium smegmatis helicase Lhr bound to ssDNA and AMP-PNP
Classification: HYDROLASE/DNA
Source organism: Mycobacterium smegmatis; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.797 Å
Deposited: 2017-03-23
Authors: Ordonez, H., Jacewicz, A., Ferrao, R., Shuman, S.
PDB entry 5v9z: RNA hairpin structure containing 2-MeImpG analogue bound
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.51 Å
Deposited: 2017-03-24
Authors: Zhang, W., Szostak, J.W.
PDB entry 5va0: Glucocorticoid Receptor DNA Binding Domain in complex with AP-1 response element from VCAM-1 Promoter
Classification: transcription/dna
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.295 Å
Deposited: 2017-03-24
Authors: Weikum, E.R., Ortlund, E.A.
PDB entry 5va1: Cryo-EM structure of the human ether-a-go-go related K+ channel
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.7 Å
Deposited: 2017-03-24
Authors: Wang, W.W., MacKinnon, R.
PDB entry 5va2: Cryo-EM structure of the human ether-a-go-go related K+ channel
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.8 Å
Deposited: 2017-03-24
Authors: Wang, W.W., MacKinnon, R.
PDB entry 5va3: Cryo-EM structure of the human ether-a-go-go related K+ channel
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 4 Å
Deposited: 2017-03-24
Authors: Wang, W.W., MacKinnon, R.
PDB entry 5va4: TRIM-Cyclophilin A B-box 2 and coiled-coil chimera
Classification: LIGASE
Source organism: Aotus trivirgatus; Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.306 Å
Deposited: 2017-03-24
Authors: Wagner, J.M., Ganser-Pornillos, B.K., Pornillos, O.W.
PDB entry 5va6: CRYSTAL STRUCTURE OF ATXR5 IN COMPLEX WITH HISTONE H3.1 MONO-METHYLATED ON R26
Classification: TRANSFERASE/DNA BINDING PROTEIN
Source organism: Ricinus communis; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2017-03-24
Authors: Bergamin, E., Sarvan, S., Malette, J., Eram, M., Yeung, S., Mongeon, V., Joshi, M., Brunzelle, J.S., Michaels, S.D., Blais, A., Vedadi, M., Couture, J.-F.
PDB entry 5va7: Glucocorticoid Receptor DNA Binding Domain - IL11 AP-1 recognition element Complex
Classification: transcription/dna
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.153 Å
Deposited: 2017-03-24
Authors: Weikum, E.R., Ortlund, E.A.
PDB entry 5va8: Crystal Structure of Short-chain dehydrogenase/reductase SDR from Burkholderia phymatum in complex with NADP
Classification: OXIDOREDUCTASE
Source organism: Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2017-03-24
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5va9: Human pancreatic alpha amylase in complex with peptide inhibitor piHA-L5(d10Y)
Classification: hydrolase/hydrolase inhibitor
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.55 Å
Deposited: 2017-03-24
Authors: Caner, S., Brayer, G.D.
PDB entry 5vaa: Crystal structure of mouse IgG2a Fc T370K mutant
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2017-03-24
Authors: Armstrong, A.A., Gilliland, G.L.
PDB entry 5vab: Crystal structure of ATXR5 PHD domain in complex with histone H3
Classification: TRANSFERASE/DNA BINDING PROTEIN
Source organism: Glycine max; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.702 Å
Deposited: 2017-03-24
Authors: Bergamin, E., Sarvan, S., Malette, J., Eram, M., Yeung, S., Mongeon, V., Joshi, M., Brunzelle, J.S., Michaels, S.D., Blais, A., Vedadi, M., Couture, J.-F.
PDB entry 5vac: Crystal Structure of ATXR5 SET domain in complex with K36me3 histone H3 peptide
Classification: TRANSFERASE/DNA BINDING PROTEIN
Source organism: Ricinus communis; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.949 Å
Deposited: 2017-03-24
Authors: Bergamin, E., Sarvan, S., Malette, J., Eram, M., Yeung, S., Mongeon, V., Joshi, M., Brunzelle, J.S., Michaels, S.D., Blais, A., Vedadi, M., Couture, J.F.
PDB entry 5vad: Crystal structure of human Prolyl-tRNA synthetase (PRS) in complex with inhibitor
Classification: LIGASE/LIGASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.36 Å
Deposited: 2017-03-24
Authors: Okada, K., Skene, R.J.
PDB entry 5vae: Crystal structure of accessory secretion protein 1 and 3
Classification: CELL ADHESION
Source organism: Streptococcus gordonii
Experimental method: X-RAY DIFFRACTION
Resolution: 3.106 Å
Deposited: 2017-03-25
Authors: Chen, Y., Rapoport, T.A., Jeffrey, P.D.
PDB entry 5vaf: Crystal structure of accessory secretion protein 1
Classification: CELL ADHESION
Source organism: Streptococcus gordonii
Experimental method: X-RAY DIFFRACTION
Resolution: 2.771 Å
Deposited: 2017-03-25
Authors: Chen, Y., Rapoport, T.A., Jeffrey, P.D.
PDB entry 5vag: Crystal structure of H7-specific antibody m826 in complex with the HA1 domain of hemagglutinin from H7N9 influenza virus
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2017-03-26
Authors: Song, H., Ying, T., Ji, X.
PDB entry 5vah: Crystal structure of ATXR5 SET domain in complex with histone H3 di-methylated on R26
Classification: TRANSFERASE/DNA BINDING PROTEIN
Source organism: Ricinus communis; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2017-03-26
Authors: Bergamin, E., Sarvan, S., Malette, J., Eram, M., Yeung, S., Mongeon, V., Joshi, M., Brunzelle, J.S., Michaels, S.D., Blais, A., Vedadi, M., Couture, J.-F.
PDB entry 5vai: Cryo-EM structure of the activated Glucagon-like peptide-1 receptor in complex with G protein
Classification: Signaling Protein/Hormone
Source organism: Bos taurus; Homo sapiens; Lama glama; Oryctolagus cuniculus; Rattus norvegicus; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.1 Å
Deposited: 2017-03-27
Authors: Zhang, Y., Sun, B., Feng, D., Hu, H., Chu, M., Qu, Q., Tarrasch, J.T., Li, S., Kobilka, T.S., Kobilka, B.K., Skiniotis, G.
PDB entry 5vaj: BhRNase H - amide-RNA/DNA complex
Classification: hydrolase/rna/dna
Source organism: Bacillus halodurans; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2017-03-27
Authors: Pallan, P.S., Egli, M.
PDB entry 5vak: Crystal Structure of Beta-Klotho, Domain 1
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens; Lama glama
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2017-03-27
Authors: Lee, S., Schlessinger, J.
PDB entry 5val: BRAF in Complex with N-(3-(tert-butyl)phenyl)-4-methyl-3-(6-morpholinopyrimidin-4-yl)benzamide
Classification: TRANSFERASE/TRANSFERASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.26 Å
Deposited: 2017-03-27
Authors: Mamo, M., Appleton, B.A.
PDB entry 5vam: BRAF in Complex with RAF709
Classification: TRANSFERASE/TRANSFERASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2017-03-27
Authors: Mamo, M., Appleton, B.A.
PDB entry 5van: Crystal Structure of Beta-Klotho
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens; Lama glama
Experimental method: X-RAY DIFFRACTION
Resolution: 2.202 Å
Deposited: 2017-03-27
Authors: Lee, S., Schlessinger, J.
PDB entry 5vao: Crystal structure of eVP30 C-terminus and eNP peptide
Classification: VIRAL PROTEIN
Source organism: Ebola virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.56 Å
Deposited: 2017-03-27
Authors: XU, W., Leung, D.W., Amarasinghe, G.K.
PDB entry 5vap: Crystal structure of eVP30 C-terminus and eNP peptide
Classification: VIRAL PROTEIN
Source organism: Ebola virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2017-03-27
Authors: XU, W., WU, C., Leung, D.W., Amarasinghe, G.K.
PDB entry 5vaq: Crystal Structure of Beta-Klotho in Complex with FGF21CT
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens; Lama glama; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.606 Å
Deposited: 2017-03-27
Authors: Lee, S., Schlessinger, J.
PDB entry 5var: Crystal structure of KDM4A tandem TUDOR domain in complex with a tri-methyl lysine competitive inhibitor
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.83 Å
Deposited: 2017-03-27
Authors: Judge, R.A., Upadhyay, A.K.
PDB entry 5vas: Pekin duck egg lysozyme isoform III (DEL-III), orthorhombic form
Classification: HYDROLASE
Source organism: Anas platyrhynchos
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2017-03-27
Authors: Christie, M., Christ, D., Langley, D.B.
PDB entry 5vat: Haemophilus influenzae LpoA: Monoclinic form (Mon2) with 2 molecules per a.u.
Classification: BIOSYNTHETIC PROTEIN
Source organism: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2017-03-27
Authors: Saper, M.A., Sathiyamoorthy, K.
PDB entry 5vau: Bcl-2 complex with Beclin 1 BH3 domain
Classification: APOPTOSIS
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.754 Å
Deposited: 2017-03-28
Authors: Lee, E.F., Smith, B.J., Yao, S., Fairlie, W.D.
PDB entry 5vav: Design of a novel cyclic peptide that alleviates symptoms in a murine model of inflammatory bowel disease
Classification: DE NOVO PROTEIN
Experimental method: SOLUTION NMR
Deposited: 2017-03-28
Authors: Daly, N.L., Cobos Caceres, C.
PDB entry 5vaw: Fusion of Maltose-binding Protein and PilA from Acinetobacter baumannii AB5075
Classification: CELL ADHESION
Source organism: Acinetobacter baumannii; Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.69 Å
Deposited: 2017-03-28
Authors: Piepenbrink, K.H., Sundberg, E.J.
PDB entry 5vax: Bcl-2 complex with Beclin 1 BH3 domain
Classification: APOPTOSIS
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2017-03-28
Authors: Lee, E.F., Smith, B.J., Yao, S., Fairlie, W.D.
PDB entry 5vay: Bcl-2 complex with Beclin 1 T108D BH3 domain
Classification: APOPTOSIS
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.804 Å
Deposited: 2017-03-28
Authors: Lee, E.F., Smith, B.J., Yao, S., Fairlie, W.D.
PDB entry 5vaz: Crystal structure of a DNA primase domain from Pseudomonas aeruginosa
Classification: TRANSFERASE
Source organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2017-03-28
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5vb0: Crystal structure of fosfomycin resistance protein FosA3
Classification: TRANSFERASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.689 Å
Deposited: 2017-03-28
Authors: Klontz, E., Guenther, S., Silverstein, Z., Sundberg, E.
PDB entry 5vb2: Crystal structure of the NavAb voltage-gated sodium channel in a closed conformation
Classification: TRANSPORT PROTEIN
Source organism: Arcobacter butzleri
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2 Å
Deposited: 2017-03-28
Authors: Lenaeus, M.J., Catterall, W.A.
PDB entry 5vb3: X-ray structure of nuclear receptor ROR-gammat Ligand Binding Domain + SRC2 peptide
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2017-03-28
Authors: Li, X.
PDB entry 5vb5: X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with an inverse agonist and SRC2 peptide
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.226 Å
Deposited: 2017-03-28
Authors: Li, X.
PDB entry 5vb6: X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with an inverse agonist and SRC2 peptide
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.041 Å
Deposited: 2017-03-28
Authors: Li, X.
PDB entry 5vb7: X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with an agonist and SRC2 peptide
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.335 Å
Deposited: 2017-03-28
Authors: Li, X.
PDB entry 5vb8: Crystal structure of the NavAb voltage-gated sodium channel in an open state
Classification: TRANSPORT PROTEIN
Source organism: Arcobacter butzleri
Experimental method: X-RAY DIFFRACTION
Resolution: 2.85 Å
Deposited: 2017-03-28
Authors: Lenaeus, M.J., Catterall, W.A.
PDB entry 5vb9: IL-17A in complex with peptide
Classification: IMMUNE SYSTEM / INHIBITOR
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2017-03-28
Authors: Antonysamy, S., Russell, M., Zhang, A., Groshong, C., Manglicmot, D., Lu, F., Benach, J., Wasserman, S.R., Zhang, F., Afshar, S., Bina, H., Broughton, H., Chalmers, M., Dodge, J., Espada, A., Jones, S., Ting, J.P., Woodman, M.
PDB entry 5vba: Structure of EspG1 chaperone from the type VII (ESX-1) secretion system determined with the assistance of N-terminal T4 lysozyme fusion
Classification: CHAPERONE, HYDROLASE
Source organism: Enterobacteria phage T4; Mycobacterium kansasii ATCC 12478
Experimental method: X-RAY DIFFRACTION
Resolution: 2.27 Å
Deposited: 2017-03-29
Authors: Korotkov, K.V.
PDB entry 5vbb: Human RNA Pseudouridylate Synthase Domain Containing 1
Classification: RNA BINDING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.94 Å
Deposited: 2017-03-29
Authors: DONG, A., ZENG, H., WALKER, J.R., Bountra, C., Arrowsmith, C.H., Edwards, A.M., BROWN, P.J., WU, H., Structural Genomics Consortium (SGC)
PDB entry 5vbc: Crystal structure of ATXR5 in complex with histone H3.1
Classification: TRANSFERASE/DNA BINDING PROTEIN
Source organism: Ricinus communis; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2017-03-29
Authors: Couture, J.-F., Bergamin, E.
PDB entry 5vbd: Crystal structure of a putative UBL domain of USP9X
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2017-03-29
Authors: Dong, A., Chern, Y., Hou, F., Li, Y., Tempel, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Tong, Y., Structural Genomics Consortium (SGC)
PDB entry 5vbe: Crystal Structure of Small Molecule Disulfide 2C07 Bound to H-Ras M72C GDP
Classification: hydrolase/hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.57 Å
Deposited: 2017-03-29
Authors: Gentile, D.R., Jenkins, M.L., Moss, S.M., Burke, J.E., Shokat, K.M.
PDB entry 5vbf: Crystal structure of succinate semialdehyde dehydrogenase from Burkholderia vietnamiensis
Classification: OXIDOREDUCTASE
Source organism: Burkholderia vietnamiensis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2017-03-29
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5vbg: Crystal Structure of full-length LpoA, Monoclinic form 1, from Haemophilus influenzae
Classification: BIOSYNTHETIC PROTEIN
Source organism: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2017-03-29
Authors: Sathiyamoorthy, K., Saper, M.A.
PDB entry 5vbi: Crystal Structure of the R515W missense variant of human PGM1
Classification: ISOMERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2017-03-29
Authors: Stiers, K.M., Beamer, L.J.
PDB entry 5vbj: Sulfur as a bromine biomolecular halogen-bond acceptor
Classification: DNA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.944 Å
Deposited: 2017-03-29
Authors: Ford, M.C., Ho, P.S.
PDB entry 5vbk: Crystal structure of a galactose-binding Lectin from Mytilus californianus
Classification: SUGAR BINDING PROTEIN
Source organism: Mytilus californianus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.788 Å
Deposited: 2017-03-29
Authors: Hernandez-Santoyo, A., Garcia-Maldonado, E.
PDB entry 5vbl: Structure of apelin receptor in complex with agonist peptide
Classification: MEMBRANE PROTEIN
Source organism: Clostridium pasteurianum; Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2017-03-29
Authors: Ma, Y., Yue, Y., Ma, Y., Zhang, Q., Zhou, Q., Song, Y., Shen, Y., Li, X., Ma, X., Li, C., Hanson, M.A., Han, G.W., Sickmier, E.A., Swaminath, G., Zhao, S., Stevems, R.C., Hu, L.A., Zhong, W., Zhang, M., Xu, F.
PDB entry 5vbm: Crystal Structure of Small Molecule Disulfide 2C07 Bound to K-Ras Cys Light M72C GDP
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.49 Å
Deposited: 2017-03-29
Authors: Gentile, D.R., Jenkins, M.L., Moss, S.M., Burke, J.E., Shokat, K.M.
PDB entry 5vbn: Crystal Structure of human DNA polymerase epsilon B-subunit in complex with C-terminal domain of catalytic subunit
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2017-03-29
Authors: Baranovskiy, A.G., Gu, J., Suwa, Y., Babayeva, N.D., Tahirov, T.H.
PDB entry 5vbo: CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH LRRK2-IN-1
Classification: TRANSCRIPTION/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.3 Å
Deposited: 2017-03-30
Authors: ZHU, J.-Y., SCHONBRUNN, E.
PDB entry 5vbp: CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH RO3280
Classification: TRANSCRIPTION/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.83 Å
Deposited: 2017-03-30
Authors: EMBER, S.W., ZHU, J.-Y., SCHONBRUNN, E.
PDB entry 5vbq: CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRDT IN COMPLEX WITH BI2536
Classification: TRANSCRIPTION/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2017-03-30
Authors: EMBER, S.W., ZHU, J.-Y., SCHONBRUNN, E.
PDB entry 5vbr: CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRDT IN COMPLEX WITH Volasertib
Classification: TRANSCRIPTION/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2017-03-30
Authors: EMBER, S.W., ZHU, J.-Y., SCHONBRUNN, E.
PDB entry 5vbs: Structural basis for a six letter alphabet including GATCKX
Classification: transferase/dna
Source organism: Moloney murine leukemia virus (isolate Shinnick); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.749 Å
Deposited: 2017-03-30
Authors: Singh, I., Georgiadis, M.M.
PDB entry 5vbt: Crystal structure of a highly specific and potent USP7 ubiquitin variant inhibitor
Classification: DE NOVO PROTEIN
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 1.51 Å
Deposited: 2017-03-30
Authors: DONG, A., DONG, X., LIU, L., GUO, Y., LI, Y., ZHANG, W., WALKER, J.R., SIDHU, S., Bountra, C., Arrowsmith, C.H., Edwards, A.M., TONG, Y., Structural Genomics Consortium (SGC)
PDB entry 5vbu: Crystal Structure of Human Cytochrome P450 21A2 Hydroxyprogesterone Complex
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.31 Å
Deposited: 2017-03-30
Authors: Pallan, P.S., Egli, M.
PDB entry 5vbx: Crystal structure of holo-[acyl-carrier-protein] synthase (AcpS) from Escherichia coli
Classification: TRANSFERASE
Source organism: Escherichia coli (strain K12)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2017-03-30
Authors: Marcella, A.M., Barb, A.W.
PDB entry 5vbz: Crystal Structure of Small Molecule Disulfide 2C07 Bound to H-Ras M72C GppNHp
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2017-03-30
Authors: Gentile, D.R., Jenkins, M.L., Moss, S.M., Burke, J.E., Shokat, K.M.
PDB entry 5vc0: Crystal structure of human CYP3A4 bound to ritonavir
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2017-03-30
Authors: Sevrioukova, I.
PDB entry 5vc1: Crystal structure of L-selectin lectin/EGF domains
Classification: CELL ADHESION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.94 Å
Deposited: 2017-03-30
Authors: Wedepohl, S., Dernedde, J., Vahedi-Faridi, A., Tauber, R., Saenger, W., Bulut, H.
PDB entry 5vc2: Crystal structure of a serine hydroxymethyltransferase from Helicobacter pylori
Classification: TRANSFERASE
Source organism: Helicobacter pylori (strain G27)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2017-03-30
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5vc3: CRYSTAL STRUCTURE OF HUMAN WEE1 KINASE DOMAIN IN COMPLEX WITH BOSUTINIB
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.97 Å
Deposited: 2017-03-30
Authors: Zhu, J.-Y., Schonbrunn, E.
PDB entry 5vc4: Crystal structure of HUMAN WEE1 KINASE domain in complex with Bosutinib-isomer
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2017-03-30
Authors: Zhu, J.-Y., Schonbrunn, E.
PDB entry 5vc5: Crystal structure of human WEE1 kinase domain in complex with PD-166285
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.93 Å
Deposited: 2017-03-31
Authors: Zhu, J.-Y., Schonbrunn, E.
PDB entry 5vc6: crystal structure of human WEE1 kinase domain in complex with PHA-848125
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2017-03-31
Authors: Zhu, J.-Y., Schonbrunn, E.
PDB entry 5vc7: VCP like ATPase from T. acidophilum (VAT) - conformation 1
Classification: HYDROLASE
Source organism: Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.9 Å
Deposited: 2017-03-31
Authors: Ripstein, Z.A., Huang, R., Augustyniak, R., Kay, L.E., Rubinstein, J.L.
PDB entry 5vc8: Crystal structure of the WHSC1 PWWP1 domain
Classification: DNA BINDING PROTEIN
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2017-03-31
Authors: Qin, S., Tempel, W., Dong, A., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
PDB entry 5vc9: Zinc finger of human CXXC4 in complex with CpG DNA
Classification: DNA BINDING PROTEIN
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2017-03-31
Authors: Liu, K., Xu, C., Tempel, W., Walker, J.R., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
PDB entry 5vca: VCP like ATPase from T. acidophilum (VAT)-Substrate bound conformation
Classification: HYDROLASE
Source organism: Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.8 Å
Deposited: 2017-03-31
Authors: Ripstein, Z.A., Huang, R., Augustyniak, R., Kay, L.E., Rubinstein, J.L.
PDB entry 5vcb: Crystal structure of holo-(acyl-carrier-protein) synthase:holo(acyl-carrier-protein) complex from Escherichia Coli.
Classification: TRANSFERASE
Source organism: Escherichia coli (strain K12); Escherichia coli O45:K1 (strain S88 / ExPEC)
Experimental method: X-RAY DIFFRACTION
Resolution: 4.1 Å
Deposited: 2017-03-31
Authors: Marcella, A.M., Barb, A.W.
PDB entry 5vcc: Crystal structure of human CYP3A4 bound to glycerol
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2017-03-31
Authors: Sevrioukova, I.
PDB entry 5vcd: Crystal structure of the cysteine depleted CYP3A4 bound to glycerol
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2017-03-31
Authors: Sevrioukova, I.
PDB entry 5vce: Crystal structure of the cysteine depleted CYP3A4 bound to ritonavir
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2017-03-31
Authors: Sevrioukova, I.
PDB entry 5vcf: RNA hairpin structure containing tetraloop/receptor motif, complexed with 2-MeImpG analogue
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2017-03-31
Authors: Zhang, W., Szostak, J.W.
PDB entry 5vcg: Crystal structure of the cysteine depleted CYP3A4 bound to bromoergocryptine
Classification: OXIDOREDUCTASE/SUBSTRATE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2017-03-31
Authors: Sevrioukova, I.
PDB entry 5vch: Crystal structure of full-length Kluyveromyces lactis Kap123
Classification: PROTEIN TRANSPORT
Source organism: Kluyveromyces lactis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2017-03-31
Authors: An, S., Yoon, J., Song, J.-J., Cho, U.-S.
PDB entry 5vci: RNA hairpin structure containing tetraloop/receptor motif, complexed with 2-MeImpG analogue
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2017-03-31
Authors: Szostak, J.W., Zhang, W.
PDB entry 5vcj: Structure of alpha-galactosylphytosphingosine bound by CD1d and in complex with the Va14Vb8.2 TCR
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.16 Å
Deposited: 2017-03-31
Authors: Wang, J., Zajonc, D.M.
PDB entry 5vck: HIV Protease (PR) with TL-3 in the active site and (Z)-N-(thiazol-2-yl)-N'-tosylcarbamimidate in the exosite
Classification: HYDROLASE
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2017-03-31
Authors: Tiefenbrunn, T., Stout, C.D.
PDB entry 5vcl: Structure of the Qdm peptide bound to Qa-1a
Classification: IMMUNE SYSTEM
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2017-03-31
Authors: Ying, G., Zajonc, D.M.
PDB entry 5vcm: Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase with bound UDP and Manganese
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.599 Å
Deposited: 2017-03-31
Authors: Sanders, J.H., Kadirvelraj, R., Wood, Z.A.
PDB entry 5vcn: THE CRYSTAL STRUCTURE OF DER P 1 ALLERGEN COMPLEXED WITH FAB FRAGMENT OF MAB 5H8
Classification: IMMUNE SYSTEM
Source organism: Dermatophagoides pteronyssinus; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2017-03-31
Authors: Osinski, T., Majorek, K.A., Pomes, A., Offermann, L.R., Osinski, S., Glesner, J., Vailes, L.D., Chapman, M.D., Minor, W., Chruszcz, M.
PDB entry 5vco: THE CRYSTAL STRUCTURE OF DER P 1 ALLERGEN COMPLEXED WITH FAB FRAGMENT OF MAB 10B9
Classification: IMMUNE SYSTEM
Source organism: Dermatophagoides pteronyssinus; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.74 Å
Deposited: 2017-03-31
Authors: Osinski, T., Majorek, K.A., Pomes, A., Offermann, L.R., Osinski, S., Glesner, J., Vailes, L.D., Chapman, M.D., Minor, W., Chruszcz, M.
PDB entry 5vcp: Crystal structure of a peptide deformylase from Burkholderia xenovorans in complex with actinonin
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Paraburkholderia xenovorans (strain LB400)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2017-03-31
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5vcq: A Hyrdrogen Producing Hybrid Streptavidin-Diiron Catalyst
Classification: Biotin Binding Protein
Source organism: Streptomyces avidinii
Experimental method: X-RAY DIFFRACTION
Resolution: 2.051 Å
Deposited: 2017-03-31
Authors: Simmons, C.R., Roy, A., Vaughn, M.D., Allen, J.P., Ghirlanda, G.
PDB entry 5vcr: Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase with bound uranium dioxide
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.992 Å
Deposited: 2017-03-31
Authors: Sanders, J.H., Kadirvelraj, R., Wood, Z.A.
PDB entry 5vcs: Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase with Bound Acceptor
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.799 Å
Deposited: 2017-03-31
Authors: Sanders, J.H., Kadirvelraj, R., Wood, Z.A.