LiteFold/PDB huggingface dataset:
PDB entry 4iao: Crystal structure of Sir2 C543S mutant in complex with SID domain of Sir4
Classification: HYDROLASE/TRANSCRIPTION
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.901 Å
Deposited: 2012-12-07
Authors: Hsu, H.C., Wang, C.L., Wang, M., Yang, N., Chen, Z., Sternglanz, R., Xu, R.M.
PDB entry 4iap: Crystal structure of PH domain of Osh3 from Saccharomyces cerevisiae
Classification: LIPID BINDING PROTEIN/ HYDRORASE
Source organism: Enterobacteria phage T4; Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2012-12-07
Authors: Tong, J., Im, Y.J.
PDB entry 4iaq: Crystal structure of the chimeric protein of 5-HT1B-BRIL in complex with dihydroergotamine (PSI Community Target)
Classification: Signaling Protein, Electron Transport
Source organism: Escherichia coli; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2012-12-07
Authors: Wang, C., Jiang, Y., Ma, J., Wu, H., Wacker, D., Katritch, V., Han, G.W., Liu, W., Huang, X., Vardy, E., McCorvy, J.D., Gao, X., Zhou, E.X., Melcher, K., Zhang, C., Bai, F., Yang, H., Yang, L., Jiang, H., Roth, B.L., Cherezov, V., Stevens, R.C., Xu, H.E., GPCR Network (GPCR)
PDB entry 4iar: Crystal structure of the chimeric protein of 5-HT1B-BRIL in complex with ergotamine (PSI Community Target)
Classification: SIGNALING PROTEIN, ELECTRON TRANSPORT
Source organism: Escherichia coli; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2012-12-07
Authors: Wang, C., Jiang, Y., Ma, J., Wu, H., Wacker, D., Katritch, V., Han, G.W., Liu, W., Huang, X., Vardy, E., McCorvy, J.D., Gao, X., Zhou, E.X., Melcher, K., Zhang, C., Bai, F., Yang, H., Yang, L., Jiang, H., Roth, B.L., Cherezov, V., Stevens, R.C., Xu, H.E., GPCR Network (GPCR)
PDB entry 4ias: HEW Lysozyme by langmuir- blodgett modified vapour diffusion
Classification: HYDROLASE
Source organism: Gallus gallus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2012-12-07
Authors: Belmonte, L., Pechkova, E., Riekel, C., Scudieri, D., Nicolini, C.
PDB entry 4iat: HEW Lysozyme by langmuir- blodgett modified vapour diffusion
Classification: HYDROLASE
Source organism: Gallus gallus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2012-12-07
Authors: Belmonte, L., Pechkova, E., Riekel, C., Scudieri, D., Nicolini, C.
PDB entry 4iau: Atomic resolution structure of Geodin, a beta-gamma crystallin from Geodia cydonium
Classification: UNKNOWN FUNCTION
Source organism: Geodia cydonium
Experimental method: X-RAY DIFFRACTION
Resolution: 0.99 Å
Deposited: 2012-12-07
Authors: Vergara, A., Grassi, M., Sica, F., Mazzarella, L., Merlino, A.
PDB entry 4iav: G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from Thermoactinomyces vulgaris with N-Sulfamoyl-L-phenylalanine
Classification: HYDROLASE
Source organism: Thermoactinomyces vulgaris
Experimental method: X-RAY DIFFRACTION
Resolution: 1.35 Å
Deposited: 2012-12-07
Authors: Timofeev, V.I., Kuznetsov, S.A., Akparov, V.K., Kuranova, I.P.
PDB entry 4iaw: Engineered human lipocalin 2 (C26) in complex with Y-DTPA
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2012-12-07
Authors: Eichinger, A., Skerra, A.
PDB entry 4iax: Engineered human lipocalin 2 (CL31) in complex with Y-DTPA
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2012-12-07
Authors: Eichinger, A., Skerra, A.
PDB entry 4iay: Room temperature X-ray Structure of cAMP dependent protein kinase A in complex with high Sr2+ concentration, ADP and phosphorylated peptide pSP20
Classification: Transferase/Peptide
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2012-12-07
Authors: Gerlits, O., Kovalevsky, A.
PDB entry 4iaz: Structure of cAMP dependent protein kinase A in complex with high Ba2+ concentration, ADP and phosphorylated peptide pSP20
Classification: Transferase/Peptide
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2012-12-07
Authors: Gerlits, O., Kovalevsky, A.
PDB entry 4ib0: X-ray Structure of cAMP dependent protein kinase A in complex with high Na+ concentration, ADP and phosphorylated peptide pSP20
Classification: Transferase/Peptide
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.87 Å
Deposited: 2012-12-07
Authors: Gerlits, O., Kovalevsky, A.
PDB entry 4ib1: Structure of cAMP dependent protein kinase A in complex with high K+ concentration, ADP and phosphorylated peptide pSP20
Classification: Transferase/Peptide
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.63 Å
Deposited: 2012-12-07
Authors: Gerlits, O., Kovalevsky, A.
PDB entry 4ib2: Crystal structure of a putative lipoprotein (RUMGNA_00858) from Ruminococcus gnavus ATCC 29149 at 1.76 A resolution
Classification: TRANSPORT PROTEIN
Source organism: Ruminococcus gnavus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.76 Å
Deposited: 2012-12-07
Authors: Joint Center for Structural Genomics (JCSG)
PDB entry 4ib3: Structure of cAMP dependent protein kinase A in complex with ADP, phosphorylated peptide pSP20, and no metal
Classification: Transferase/Peptide
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2012-12-07
Authors: Gerlits, O., Kovalevsky, A.
PDB entry 4ib4: Crystal structure of the chimeric protein of 5-HT2B-BRIL in complex with ergotamine
Classification: SIGNALING PROTEIN, ELECTRON TRANSPORT
Source organism: Escherichia coli; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2012-12-07
Authors: Wacker, D., Wang, C., Katritch, V., Han, G.W., Huang, X., Vardy, E., McCorvy, J.D., Jiang, Y., Chu, M., Siu, F.Y., Liu, W., Xu, H.E., Cherezov, V., Roth, B.L., Stevens, R.C., GPCR Network (GPCR)
PDB entry 4ib5: Structure of human protein kinase CK2 catalytic subunit in complex with a CK2beta-competitive cyclic peptide
Classification: TRANSFERASE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2012-12-08
Authors: Raaf, J., Guerra, B., Neundorf, I., Bopp, B., Issinger, O.-G., Jose, J., Pietsch, M., Niefind, K.
PDB entry 4ib6: Bovine beta-lactoglobulin (isoform A) in complex with lauric acid (C12)
Classification: TRANSPORT PROTEIN
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2012-12-08
Authors: Loch, J.I., Bonarek, P., Polit, A., Swiatek, S., Dziedzicka-Wasylewska, M., Lewinski, K.
PDB entry 4ib7: Bovine beta-lactoglobulin (isoform A) in complex with dodecyltrimethylammonium (DTAC)
Classification: TRANSPORT PROTEIN
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2012-12-08
Authors: Loch, J.I., Bonarek, P., Polit, A., Swiatek, S., Dziedzicka-Wasylewska, M., Lewinski, K.
PDB entry 4ib8: Bovine beta-lactoglobulin (isoform A) in complex with dodecyl sulphate (SDS)
Classification: TRANSPORT PROTEIN
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2012-12-08
Authors: Loch, J.I., Bonarek, P., Polit, A., Swiatek, S., Dziedzicka-Wasylewska, M., Lewinski, K.
PDB entry 4ib9: Bovine beta-lactoglobulin (isoform B) in complex with dodecyltrimethylammonium (DTAC)
Classification: TRANSPORT PROTEIN
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2012-12-08
Authors: Loch, J.I., Bonarek, P., Polit, A., Swiatek, S., Dziedzicka-Wasylewska, M., Lewinski, K.
PDB entry 4iba: Bovine beta-lactoglobulin (isoform B) in complex with dodecyl sulphate (SDS)
Classification: TRANSPORT PROTEIN
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2012-12-08
Authors: Loch, J.I., Bonarek, P., Polit, A., Swiatek, S., Dziedzicka-Wasylewska, M., Lewinski, K.
PDB entry 4ibb: Ebola virus VP35 bound to small molecule
Classification: TRANSCRIPTION/TRANSCRIPTION inhibitor
Source organism: Ebola virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.752 Å
Deposited: 2012-12-08
Authors: Brown, C.S., Leung, D.W., Xu, W., Borek, D.M., Otwinowski, Z., Ramanan, P., Stubbs, A.J., Peterson, D.S., Binning, J.M., Amarasinghe, G.K., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4ibc: Ebola virus VP35 bound to small molecule
Classification: TRANSCRIPTION/TRANSCRIPTION inhibitor
Source organism: Ebola virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.745 Å
Deposited: 2012-12-08
Authors: Brown, C.S., Leung, D.W., Xu, W., Borek, D.M., Otwinowski, Z., Ramanan, P., Stubbs, A.J., Peterson, D.S., Binning, J.M., Amarasinghe, G.K.
PDB entry 4ibd: Ebola virus VP35 bound to small molecule
Classification: TRANSCRIPTION/TRANSCRIPTION inhibitor
Source organism: Ebola virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.84 Å
Deposited: 2012-12-08
Authors: Brown, C.S., Leung, D.W., Xu, W., Borek, D.M., Otwinowski, Z., Ramanan, P., Stubbs, A.J., Peterson, D.S., Binning, J.M., Amarasinghe, G.K.
PDB entry 4ibe: Ebola virus VP35 bound to small molecule
Classification: TRANSCRIPTION/TRANSCRIPTION inhibitor
Source organism: Ebola virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2012-12-08
Authors: Brown, C.S., Leung, D.W., Xu, W., Borek, D.M., Otwinowski, Z., Ramanan, P., Stubbs, A.J., Peterson, D.S., Binning, J.M., Amarasinghe, G.K., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4ibf: Ebola virus VP35 bound to small molecule
Classification: TRANSCRIPTION/TRANSCRIPTION inhibitor
Source organism: Ebola virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.291 Å
Deposited: 2012-12-08
Authors: Brown, C.S., Leung, D.W., Xu, W., Borek, D.M., Otwinowski, Z., Ramanan, P., Stubbs, A.J., Peterson, D.S., Binning, J.M., Amarasinghe, G.K., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4ibg: Ebola virus VP35 bound to small molecule
Classification: TRANSCRIPTION/TRANSCRIPTION inhibitor
Source organism: Ebola virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.413 Å
Deposited: 2012-12-08
Authors: Brown, C.S., Leung, D.W., Xu, W., Borek, D.M., Otwinowski, Z., Ramanan, P., Stubbs, A.J., Peterson, D.S., Binning, J.M., Amarasinghe, G.K.
PDB entry 4ibi: Ebola virus VP35 bound to small molecule
Classification: TRANSCRIPTION/TRANSCRIPTION inhibitor
Source organism: Ebola virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.473 Å
Deposited: 2012-12-08
Authors: Brown, C.S., Leung, D.W., Xu, W., Borek, D.M., Otwinowski, Z., Ramanan, P., Stubbs, A.J., Peterson, D.S., Binning, J.M., Amarasinghe, G.K.
PDB entry 4ibj: Ebola virus VP35 bound to small molecule
Classification: TRANSCRIPTION/TRANSCRIPTION inhibitor
Source organism: Ebola virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.54 Å
Deposited: 2012-12-08
Authors: Brown, C.S., Leung, D.W., Xu, W., Borek, D.M., Otwinowski, Z., Ramanan, P., Stubbs, A.J., Peterson, D.S., Binning, J.M., Amarasinghe, G.K.
PDB entry 4ibk: Ebola virus VP35 bound to small molecule
Classification: TRANSCRIPTION/TRANSCRIPTION inhibitor
Source organism: Ebola virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2012-12-08
Authors: Brown, C.S., Leung, D.W., Xu, W., Borek, D.M., Otwinowski, Z., Ramanan, P., Stubbs, A.J., Peterson, D.S., Binning, J.M., Amarasinghe, G.K.
PDB entry 4ibl: Rubidium Sites in Blood Coagulation Factor VIIa
Classification: HYDROLASE
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2012-12-08
Authors: Vadivel, K., Schmidt, A., Cascio, D., Padmanabhan, K., Bajaj, S.P.
PDB entry 4ibm: Crystal structure of insulin receptor kinase domain in complex with an inhibitor Irfin-1
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2012-12-08
Authors: Wu, J., Anastassiadis, T., Duong-Ly, K.C., Peterson, J.R.
PDB entry 4ibn: Crystal structure of LC9-RNase H1, a type 1 RNase H with the type 2 active-site motif
Classification: HYDROLASE
Source organism: uncultured organism
Experimental method: X-RAY DIFFRACTION
Resolution: 1.62 Å
Deposited: 2012-12-09
Authors: Nguyen, T.-N., You, D.-J., Kanaya, E., Koga, Y., Kanaya, S.
PDB entry 4ibo: Crystal structure of a putative gluconate dehydrogenase from agrobacterium tumefaciens (target EFI-506446)
Classification: OXIDOREDUCTASE
Source organism: Agrobacterium fabrum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2012-12-09
Authors: Vetting, M.W., Bouvier, J.T., Groninger-Poe, F., Morisco, L.L., Wasserman, S.R., Sojitra, S., Imker, H.J., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4ibp: Crystal structure of a glutathione transferase family member from Pseudomonas fluorescens Pf-5, target EFI-900011, with bound glutathione
Classification: TRANSFERASE
Source organism: Pseudomonas fluorescens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2012-12-09
Authors: Vetting, M.W., Sauder, J.M., Morisco, L.L., Wasserman, S.R., Sojitra, S., Imker, H.J., Burley, S.K., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4ibq: Human p53 core domain with hot spot mutation R273C
Classification: DNA BINDING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2012-12-09
Authors: Rozenberg, H., Eldar, A., Diskin-Posner, Y., Shakked, Z.
PDB entry 4ibr: Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying G238S/E104K mutations
Classification: HYDROLASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2012-12-09
Authors: Dellus-Gur, E., Toth-Petroczy, A., Elias, M., Tawfik, D.S.
PDB entry 4ibs: Human p53 core domain with hot spot mutation R273H (form I)
Classification: DNA BINDING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.78 Å
Deposited: 2012-12-09
Authors: Rozenberg, H., Eldar, A., Diskin-Posner, Y., Shakked, Z.
PDB entry 4ibt: Human p53 core domain with hot spot mutation R273H and second-site suppressor mutation T284R
Classification: DNA BINDING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2012-12-09
Authors: Diskin-Posner, Y., Eldar, A., Rozenberg, H., Shakked, Z.
PDB entry 4ibu: Human p53 core domain with hot spot mutation R273C and second-site suppressor mutation T284R in sequence-specific complex with DNA
Classification: DNA BINDING PROTEIN/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2012-12-09
Authors: Eldar, A., Rozenberg, H., Diskin-Posner, Y., Shakked, Z.
PDB entry 4ibv: Human p53 core domain with hot spot mutation R273C and second-site suppressor mutation S240R in sequence-specific complex with DNA
Classification: DNA BINDING PROTEIN/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2012-12-09
Authors: Eldar, A., Rozenberg, H., Diskin-Posner, Y., Shakked, Z.
PDB entry 4ibw: Human p53 core domain with hot spot mutation R273H and second-site suppressor mutation T284R in sequence-specific complex with DNA
Classification: DNA BINDING PROTEIN/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.791 Å
Deposited: 2012-12-09
Authors: Eldar, A., Rozenberg, H., Diskin-Posner, Y., Shakked, Z.
PDB entry 4ibx: Crystal structure of stabilized TEM-1 beta-lactamase variant v.13
Classification: HYDROLASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.68 Å
Deposited: 2012-12-09
Authors: Dellus-Gur, E., Toth-Petroczy, A., Elias, M., Tawfik, D.S.
PDB entry 4iby: Human p53 core domain with hot spot mutation R273H and second-site suppressor mutation S240R
Classification: DNA BINDING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2012-12-09
Authors: Eldar, A., Rozenberg, H., Diskin-Posner, Y., Shakked, Z.
PDB entry 4ibz: Human p53 core domain with hot spot mutation R273C and second-site suppressor mutation T284R
Classification: DNA BINDING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.92 Å
Deposited: 2012-12-09
Authors: Eldar, A., Rozenberg, H., Diskin-Posner, Y., Shakked, Z.
PDB entry 4ic0: Crystal Structure of PAI-1 in Complex with Gallate
Classification: HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.32 Å
Deposited: 2012-12-09
Authors: Hong, Z.B., Lin, Z.H., Gong, L.H., Huang, M.D.
PDB entry 4ic1: Crystal structure of SSO0001
Classification: STRUCTURAL GENOMICS, UNKNOWN FUNCTION
Source organism: Sulfolobus solfataricus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2012-12-09
Authors: Nocek, B., Skarina, T., Lemak, S., Beloglazova, N., Flick, R., Brown, G., Savchenko, A., Joachimiak, A., Yakunin, A.F., Midwest Center for Structural Genomics (MCSG)
PDB entry 4ic2: Crystal structure of the XIAP RING domain
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2012-12-09
Authors: Linke, K., Nakatani, Y., Day, C.L.
PDB entry 4ic3: Crystal structure of the F495L mutant XIAP RING domain
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.783 Å
Deposited: 2012-12-09
Authors: Nakatani, Y., Day, C.L.
PDB entry 4ic4: Crystal structure of Osh3 ORD from Saccharomyces cerevisiae
Classification: LIPID BINDING PROTEIN
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2012-12-09
Authors: Tong, J., Im, Y.J.
PDB entry 4ic5: Crystal structure of Deg5
Classification: HYDROLASE
Source organism: Arabidopsis thaliana
Experimental method: X-RAY DIFFRACTION
Resolution: 2.607 Å
Deposited: 2012-12-10
Authors: Gong, W., Sun, W., Fan, H., Gao, F., Liu, L.
PDB entry 4ic6: Crystal structure of Deg8
Classification: HYDROLASE
Source organism: Arabidopsis thaliana
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2012-12-10
Authors: Gong, W., Sun, W., Fan, H., Gao, F., Liu, L.
PDB entry 4ic7: Crystal structure of the ERK5 kinase domain in complex with an MKK5 binding fragment
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2012-12-10
Authors: Gogl, G., Remenyi, A.
PDB entry 4ic8: Crystal structure of the apo ERK5 kinase domain
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2012-12-10
Authors: Gogl, G., Remenyi, A.
PDB entry 4ic9: Crystal structure of the full-length matrix subunit (p15) of the Feline Immunodeficiency Virus (FIV) Gag polyprotein
Classification: VIRAL PROTEIN
Source organism: Feline immunodeficiency virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2012-12-10
Authors: Serriere, J., Robert, X., Perez, M., Gouet, P., Guillon, C.
PDB entry 4ica: Crystal structure of a C-terminal truncated form of the matrix subunit (p15) of Feline Immunodeficiency Virus (FIV)
Classification: VIRAL PROTEIN
Source organism: Feline immunodeficiency virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2012-12-10
Authors: Serriere, J., Robert, X., Perez, M., Gouet, P., Guillon, C.
PDB entry 4icb: PROLINE CIS-TRANS ISOMERS IN CALBINDIN D9K OBSERVED BY X-RAY CRYSTALLOGRAPHY
Classification: CALCIUM-BINDING PROTEIN
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 1991-08-27
Authors: Svensson, L.A.
PDB entry 4icc: Crystal structure of human AKR1B10 complexed with NADP+ and JF0064
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.752 Å
Deposited: 2012-12-10
Authors: Cousido-Siah, A., Ruiz, F.X., Mitschler, A., Porte, S., de Lera, A.R., Martin, M.J., de la Fuente, J.A., Klebe, G., Farres, J., Pares, X., Podjarny, A.
PDB entry 4icd: REGULATION OF ISOCITRATE DEHYDROGENASE BY PHOSPHORYLATION INVOLVES NO LONG-RANGE CONFORMATIONAL CHANGE IN THE FREE ENZYME
Classification: OXIDOREDUCTASE (NAD(A)-CHOH(D))
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 1989-12-28
Authors: Hurley, J.H., Dean, A.M., Thorsness, P.E., Koshlandjunior, D.E., Stroud, R.M.
PDB entry 4icg: N-terminal dimerization domain of H-NS in complex with Hha (Salmonella Typhimurium)
Classification: DNA BINDING PROTEIN
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9217 Å
Deposited: 2012-12-10
Authors: Ali, S.S., Whitney, J.C., Stevenson, J., Robinson, H., Howell, P.L., Navarre, W.W.
PDB entry 4ich: Crystal structure of a putative TetR family transcriptional regulator from Saccharomonospora viridis DSM 43017
Classification: Transcription Regulator
Source organism: Saccharomonospora viridis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2012-12-10
Authors: Filippova, E.V., Minasov, G., Shuvalova, L., Kiryukhina, O., Jedrzejczak, R., Joachimiak, A., Anderson, W.F., Midwest Center for Structural Genomics (MCSG)
PDB entry 4ici: Crystal structure of a putative flavoprotein (BACEGG_01620) from Bacteroides eggerthii DSM 20697 at 1.40 A resolution
Classification: FLAVOPROTEIN
Source organism: Bacteroides eggerthii
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2012-12-10
Authors: Joint Center for Structural Genomics (JCSG)
PDB entry 4ick: Crystal structure of human AP4A hydrolase E58A mutant
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2012-12-10
Authors: Ge, H., Chen, X.
PDB entry 4icl: HIV-1 reverse transcriptase with bound fragment at the incoming dNTP binding site
Classification: transferase/transferase inhibitor
Source organism: Human immunodeficiency virus type 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2012-12-10
Authors: Bauman, J.D., Patel, D., Arnold, E.
PDB entry 4icm: Crystal structure of 5-carboxyvanillate decarboxylase LigW from Sphingomonas paucimobilis
Classification: LYASE
Source organism: Sphingobium sp. SYK-6
Experimental method: X-RAY DIFFRACTION
Resolution: 1.825 Å
Deposited: 2012-12-10
Authors: Fedorov, A.A., Fedorov, E.V., Vladimirova, A., Raushel, F.M., Almo, S.C.
PDB entry 4icn: Dihydrodipicolinate synthase from shewanella benthica
Classification: LYASE
Source organism: SHEWANELLA BENTHICA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2012-12-10
Authors: Wubben, J.M., Paxman, J.J., Dogovski, C., Parker, M.W., Perugini, M.A.
PDB entry 4icq: Structural basis for substrate recognition and reaction mechanism of bacterial aminopeptidase peps
Classification: HYDROLASE
Source organism: Streptococcus pneumoniae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2012-12-11
Authors: Ta, M.H., Kim, K.K., Lee, S.
PDB entry 4icr: Structural basis for substrate recognition and reaction mechanism of bacterial aminopeptidase peps
Classification: HYDROLASE
Source organism: Streptococcus pneumoniae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.17 Å
Deposited: 2012-12-11
Authors: Lee, S., Kim, K.K., Ta, M.H.
PDB entry 4ics: Crystal structure of PepS from Streptococcus pneumoniae in complex with a substrate
Classification: HYDROLASE
Source organism: Streptococcus pneumoniae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.97 Å
Deposited: 2012-12-11
Authors: Lee, S., Kim, K.K., Ta, M.H.
PDB entry 4ict: Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2012-12-11
Authors: Fonvielle, M., Le Du, M.-H., Lequin, O., Lecoq, A., Jacquet, M., Thai, R., Dubois, S., Grach, G., Gondry, M., Belin, P.
PDB entry 4icu: Ubiquitin-like domain of human tubulin folding cofactor E - crystal from A
Classification: CHAPERONE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2012-12-11
Authors: Janowski, R., Boutin, M., Zabala, J.C., Coll, M.
PDB entry 4icv: Ubiquitin-like domain of human tubulin folding cofactor E - crystal form B
Classification: CHAPERONE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2012-12-11
Authors: Janowski, R., Boutin, M., Zabala, J.C., Coll, M.
PDB entry 4icw: N-terminal C2 domain of human CEP120
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2012-12-11
Authors: Janowski, R., Guarin, N., Coll, M.
PDB entry 4icx: N-terminal C2 domain of human CEP120
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2012-12-11
Authors: Janowski, R., Guarin, N., Coll, M.
PDB entry 4icy: Tracing the Evolution of Angucyclinone Monooxygenases: Structural Determinants for C-12b Hydroxylation and Substrate Inhibition in PgaE
Classification: OXIDOREDUCTASE
Source organism: Streptomyces sp. PGA64
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2012-12-11
Authors: Kallio, P., Patrikainen, P., Belogurov, G., Mantsala, P., Yang, K., Niemi, J., Metsa-Ketela, M.
PDB entry 4icz: HER2 1221/1222 phosphorylation regulated by PTPN9
Classification: HYDROLASE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2012-12-11
Authors: Xu, Y.F., Wang, H.M., Liu, C.H., Yu, X., Sun, J.P.
PDB entry 4id0: Crystal structure of a glutathione transferase family member from Pseudomonas fluorescens Pf-5, target EFI-900011, with bound glutathione sulfinic acid (gso2h) and acetate
Classification: TRANSFERASE
Source organism: Pseudomonas fluorescens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.1 Å
Deposited: 2012-12-11
Authors: Vetting, M.W., Sauder, J.M., Morisco, L.L., Wasserman, S.R., Sojitra, S., Imker, H.J., Burley, S.K., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4id1: HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus type 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.87 Å
Deposited: 2012-12-11
Authors: Feng, L., Kvaratskhelia, M.
PDB entry 4id2: Crystal structure of a DUF4738 family protein (BACOVA_05496) from Bacteroides ovatus ATCC 8483 at 2.15 A resolution
Classification: STRUCTURAL GENOMICS, UNKNOWN FUNCTION
Source organism: Bacteroides ovatus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2012-12-11
Authors: Joint Center for Structural Genomics (JCSG)
PDB entry 4id3: Crystal Structure of the BRCT domain of S. Cerevisiae Rev1
Classification: PROTEIN BINDING
Source organism: Saccharomyces cerevisiae S288c
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9669 Å
Deposited: 2012-12-11
Authors: Pryor, J.M., Gakhar, L., Washington, M.T.
PDB entry 4id4: Crystal structure of chimeric beta-lactamase cTEM-17m
Classification: HYDROLASE
Source organism: Escherichia coli; Pseudomonas aeruginosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.05 Å
Deposited: 2012-12-11
Authors: Park, J., Gobeil, S., Pelletier, J.N., Berghuis, A.M.
PDB entry 4id5: HIV-1 reverse transcriptase with bound fragment at the RNase H primer grip site
Classification: transferase/transferase inhibitor
Source organism: Human immunodeficiency virus type 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2012-12-11
Authors: Bauman, J.D., Patel, D., Arnold, E.
PDB entry 4id6: Crystal Structure of Staphylococcal nuclease mutant V23I/I72L
Classification: HYDROLASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.898 Å
Deposited: 2012-12-11
Authors: Hansen, S.W., Janowska, K., Stites, W.E., Sakon, J.
PDB entry 4id7: ACK1 kinase in complex with the inhibitor cis-3-[8-amino-1-(4-phenoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclobutanol
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2012-12-11
Authors: Jin, M., Wang, J., Kleinberg, A., Kadalbajoo, M., Siu, K., Cooke, A., Bittner, M., Yao, Y., Thelemann, A., Ji, Q., Bhagwat, S., Crew, A.P., Pachter, J., Epstein, D., Mulvihill, M.J.
PDB entry 4id8: The crystal structure of a [3Fe-4S] ferredoxin associated with CYP194A4 from R. palustris HaA2
Classification: ELECTRON TRANSPORT
Source organism: Rhodopseudomonas palustris
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2012-12-11
Authors: Zhou, W.H., Zhang, T., Zhang, A.L., Bell, S.G., Wong, L.-L.
PDB entry 4id9: Crystal structure of a short-chain dehydrogenase/reductase superfamily protein from agrobacterium tumefaciens (TARGET EFI-506441) with bound nad, monoclinic form 1
Classification: OXIDOREDUCTASE
Source organism: Agrobacterium fabrum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2012-12-12
Authors: Vetting, M.W., Groninger-Poe, F., Morisco, L.L., Wasserman, S.R., Sojitra, S., Imker, H.J., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4ida: Structure of the Fragaria x ananassa enone oxidoreductase in its apo form
Classification: OXIDOREDUCTASE
Source organism: Fragaria vesca
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2012-12-12
Authors: Schiefner, A., Skerra, A.
PDB entry 4idb: Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADP+
Classification: OXIDOREDUCTASE
Source organism: Fragaria vesca
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2012-12-12
Authors: Schiefner, A., Skerra, A.
PDB entry 4idc: Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADPH and HDMF
Classification: OXIDOREDUCTASE
Source organism: Fragaria vesca
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2012-12-12
Authors: Schiefner, A., Skerra, A.
PDB entry 4idd: Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADPH and EHMF
Classification: OXIDOREDUCTASE
Source organism: Fragaria vesca
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2012-12-12
Authors: Schiefner, A., Skerra, A.
PDB entry 4ide: Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADP+ and EDHMF
Classification: OXIDOREDUCTASE
Source organism: Fragaria vesca
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2012-12-12
Authors: Schiefner, A., Skerra, A.
PDB entry 4idf: Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADPH and HMF
Classification: OXIDOREDUCTASE
Source organism: Fragaria vesca
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2012-12-12
Authors: Schiefner, A., Skerra, A.
PDB entry 4idg: Crystal structure of a short-chain dehydrogenase/reductase superfamily protein from agrobacterium tumefaciens (TARGET EFI-506441) with bound NAD, monoclinic form 2
Classification: OXIDOREDUCTASE
Source organism: Agrobacterium fabrum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2012-12-12
Authors: Vetting, M.W., Groninger-Poe, F., Morisco, L.L., Wasserman, S.R., Sojitra, S., Imker, H.J., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4idh: Crystal Structure of the large terminase subunit gp2 of bacterial virus Sf6
Classification: VIRAL PROTEIN
Source organism: Shigella phage Sf6
Experimental method: X-RAY DIFFRACTION
Resolution: 1.69 Å
Deposited: 2012-12-12
Authors: Zhao, H., Christensen, T., Kamau, Y., Tang, L.
PDB entry 4idi: Crystal Structure of Rurm1-related protein from Plasmodium Yoelii, PY06420
Classification: PROTEIN BINDING
Source organism: Plasmodium yoelii yoelii
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2012-12-12
Authors: Wernimont, A.K., Tempel, W., Lew, J., Walker, J., Arrowsmith, C.H., Edwards, A.M., Schapira, M., Bountra, C., Hui, R., Artz, J.D., Structural Genomics Consortium (SGC)
PDB entry 4idj: S.Aureus a-hemolysin monomer in complex with Fab
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.36 Å
Deposited: 2012-12-12
Authors: Strop, P.
PDB entry 4idk: HIV-1 reverse transcriptase with bound fragment at the 428 site
Classification: transferase/transferase inhibitor
Source organism: Human immunodeficiency virus type 1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2012-12-12
Authors: Bauman, J.D., Patel, D., Arnold, E.
PDB entry 4idl: Low melting temperature Anti-Cholera Toxin Llama VHH domain
Classification: IMMUNE SYSTEM
Source organism: Lama glama
Experimental method: X-RAY DIFFRACTION
Resolution: 2.09 Å
Deposited: 2012-12-12
Authors: Legler, P.M., Lam, A., Hol, W.G.J.
PDB entry 4idm: Crystal structure of the Delta-pyrroline-5-carboxylate dehydrogenase from Mycobacterium tuberculosis
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2012-12-12
Authors: Lagautriere, T., Bashiri, G., Baker, E.N.
PDB entry 4idn: Human atlastin-1 1-446, C-his6, GppNHp
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.252 Å
Deposited: 2012-12-12
Authors: Byrnes, L.J., Singh, A., Szeto, K., Benvin, N.M., O'Donnell, J.P., Zipfel, W.R., Sondermann, H.
PDB entry 4ido: human atlastin-1 1-446, C-his6, GDPAlF4-
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.091 Å
Deposited: 2012-12-12
Authors: Byrnes, L.J., Singh, A., Szeto, K., Benvin, N.M., O'Donnell, J.P., Zipfel, W.R., Sondermann, H.
PDB entry 4idp: human atlastin-1 1-446, N440T, GppNHp
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.587 Å
Deposited: 2012-12-12
Authors: Byrnes, L.J., Singh, A., Szeto, K., Benvin, N.M., O'Donnell, J.P., Zipfel, W.R., Sondermann, H.
PDB entry 4idq: human atlastin-1 1-446, N440T, GDPAlF4-
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.295 Å
Deposited: 2012-12-12
Authors: Byrnes, L.J., Singh, A., Szeto, K., Benvin, N.M., O'Donnell, J.P., Zipfel, W.R., Sondermann, H.
PDB entry 4idr: Human Carbonic Anhydrase II Proton Transfer Double Mutant
Classification: LYASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2012-12-13
Authors: Mikulski, R.M., West, D.M.
PDB entry 4ids: Crystal structure of the Delta-pyrroline-5-carboxylate dehydrogenase from Mycobacterium tuberculosis
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.04 Å
Deposited: 2012-12-13
Authors: Lagautriere, T., Bashiri, G., Baker, E.N.
PDB entry 4idt: Crystal Structure of NIK with 11-bromo-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-2-amine (T28)
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2012-12-13
Authors: Liu, J., Sudom, A., Wang, Z.
PDB entry 4idu: crystal structure of Schmallenberg virus nucleoprotein
Classification: DNA BINDING PROTEIN
Source organism: Schmallenberg virus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.08 Å
Deposited: 2012-12-13
Authors: Dong, H., Li, P., Elliott, R.M., Dong, C.
PDB entry 4idv: Crystal Structure of NIK with compound 4-{3-[2-amino-5-(2-methoxyethoxy)pyrimidin-4-yl]-1H-indol-5-yl}-2-methylbut-3-yn-2-ol (13V)
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2012-12-13
Authors: Liu, J., Sudom, A., Wang, Z.
PDB entry 4idw: Polycrystalline T6 Bovine Insulin: Anisotropic Lattice Evolution and Novel Structure Refinement Strategy
Classification: HORMONE
Source organism: Bos taurus
Experimental method: POWDER DIFFRACTION
Deposited: 2012-12-13
Authors: Margiolaki, I., Giannopoulou, A.E., Wright, J.P., Knight, L., Norrman, M., Schluckebier, G., Fitch, A., Von Dreele, R.B.
PDB entry 4idx: hexameric crystal structure of Schmallenberg virus nucleoprotein
Classification: DNA BINDING PROTEIN
Source organism: Schmallenberg virus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.21 Å
Deposited: 2012-12-13
Authors: Dong, H., Dong, C.
PDB entry 4idy: Mycobacterium Tuberculosis Methionine aminopeptidase Type 1c in complex with 2-hydroxyethyl disulfide
Classification: HYDROLASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2012-12-13
Authors: Reddi, R., Gumpena, R., Kishor, C., Addlagatta, A.
PDB entry 4idz: Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with N-oxalylglycine (NOG)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.46 Å
Deposited: 2012-12-13
Authors: Aik, W.S., McDonough, M.A., Schofield, C.J.
PDB entry 4ie0: Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with pyridine-2,4-dicarboxylate (2,4-PDCA)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.53 Å
Deposited: 2012-12-13
Authors: Aik, W.S., McDonough, M.A., Schofield, C.J.
PDB entry 4ie1: Crystal structure of human Arginase-1 complexed with inhibitor 1h
Classification: Hydrolase/Hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.0006 Å
Deposited: 2012-12-13
Authors: Cousido-Siah, A., Mitschler, A., Ruiz, F.X., Beckett, P., Van Zandt, M.C., Ji, M.K., Whitehouse, D., Ryder, T., Jagdmann, E., Andreoli, M., Mazur, A., Padmanilayam, M., Schroeter, H., Golebiowski, A., Podjarny, A.
PDB entry 4ie2: Crystal structure of human Arginase-2 complexed with inhibitor 1h
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2082 Å
Deposited: 2012-12-13
Authors: Cousido-Siah, A., Mitschler, A., Ruiz, F.X., Beckett, P., Van Zandt, M.C., Ji, M.K., Whitehouse, D., Ryder, T., Jagdmann, E., Andreoli, M., Mazur, A., Padmanilayam, M., Schroeter, H., Golebiowski, A., Podjarny, A.
PDB entry 4ie3: Crystal structure of human Arginase-2 complexed with inhbitor 1o
Classification: Hydrolase/Hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3522 Å
Deposited: 2012-12-13
Authors: Cousido-Siah, A., Mitschler, A., Ruiz, F.X., Beckett, P., Van Zandt, M.C., Ji, M.K., Whitehouse, D., Ryder, T., Jagdmann, E., Andreoli, M., Mazur, A., Padmanilayam, M., Schroeter, H., Golebiowski, A., Podjarny, A.
PDB entry 4ie4: Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with 5-carboxy-8-hydroxyquinoline (IOX1)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5048 Å
Deposited: 2012-12-13
Authors: Aik, W.S., McDonough, M.A., Schofield, C.J.
PDB entry 4ie5: Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with N-[(3-hydroxypyridin-2-yl)carbonyl]glycine (MD6)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2012-12-13
Authors: Aik, W.S., McDonough, M.A., Schofield, C.J.
PDB entry 4ie6: Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/UN9)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5036 Å
Deposited: 2012-12-13
Authors: Aik, W.S., McDonough, M.A., Schofield, C.J.
PDB entry 4ie7: Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with citrate and rhein (RHN)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6004 Å
Deposited: 2012-12-13
Authors: Aik, W.S., McDonough, M.A., Schofield, C.J.
PDB entry 4ie9: Bovine PKA C-alpha in complex with 3-pyridylmethyl-5-methyl-1H-pyrazole-3-carboxylate
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Bos taurus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.92 Å
Deposited: 2012-12-13
Authors: Dreyer, M.K., Schiffer, A., Lodge, J.
PDB entry 4iea: 14-3-3 isoform sigma in complex with a phosphorylated C-RAF peptide
Classification: PEPTIDE BINDING PROTEIN
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2012-12-13
Authors: Molzan, M., Ottmann, C.
PDB entry 4ieb: Crystal Structure of a Gly128Met mutant of the toxoplasma CDPK, TGME49_101440
Classification: TRANSFERASE
Source organism: Toxoplasma gondii
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2012-12-13
Authors: Wernimont, A.K., Artz, J.D., El Bakkouri, M., Schapira, M., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
PDB entry 4iec: Cys105 covalent modification by 2-hydroxyethyl disulfide in Mycobacterium tuberculosis methionine aminopeptidase Type 1c
Classification: HYDROLASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2012-12-13
Authors: Reddi, R., Gumpena, R., Kishor, C., Addlagatta, A.
PDB entry 4ied: Crystal Structure of FUS-1 (OXA-85), a Class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum
Classification: HYDROLASE
Source organism: Fusobacterium nucleatum subsp. polymorphum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2012-12-13
Authors: Mangani, S., Benvenuti, M., Docquier, J.D.
PDB entry 4iee: Crystal Structure of the large terminase subunit gp2 of bacterial virus Sf6 complexed with ATP-r-S
Classification: VIRAL PROTEIN
Source organism: Shigella phage Sf6
Experimental method: X-RAY DIFFRACTION
Resolution: 1.89 Å
Deposited: 2012-12-13
Authors: Zhao, H., Christensen, T., Kamau, Y., Tang, L.
PDB entry 4ief: Complex of Porphyromonas gingivalis RgpB pro- and mature domains
Classification: HYDROLASE
Source organism: Porphyromonas gingivalis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2012-12-13
Authors: de Diego, I., Veillard, F.T., Guevara, T., Potempa, B., Sztukowska, M., Potempa, J., Gomis-Ruth, F.X.
PDB entry 4ieg: Structure and interactions of the RNA-dependent RNA polymerase from bacteriophage phi12 (P1 crystal form)
Classification: TRANSFERASE
Source organism: Pseudomonas phage phi12
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2012-12-13
Authors: Ren, Z., Franklin, M.C., Ghose, R.
PDB entry 4ieh: Crystal Structure of human Bcl-2 in complex with a small molecule inhibitor targeting Bcl-2 BH3 domain interactions
Classification: APOPTOSIS/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2012-12-13
Authors: Xie, X., Kulathila, R.
PDB entry 4iei: Crystal Structure of the large terminase subunit gp2 of bacterial virus Sf6 complexed with ADP
Classification: VIRAL PROTEIN
Source organism: Shigella phage Sf6
Experimental method: X-RAY DIFFRACTION
Resolution: 2.09 Å
Deposited: 2012-12-13
Authors: Zhao, H., Christensen, T., Kamau, Y., Tang, L.
PDB entry 4iej: Crystal structure of a DNA methyltransferase 1 associated protein 1 (DMAP1) from Homo sapiens at 1.45 A resolution
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2012-12-13
Authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
PDB entry 4iel: Crystal structure of a glutathione s-transferase family protein from burkholderia ambifaria, target efi-507141, with bound glutathione
Classification: TRANSFERASE
Source organism: Burkholderia ambifaria
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2012-12-13
Authors: Vetting, M.W., Toro, R., Bhosle, R., Al Obaidi, N.F., Morisco, L.L., Wasserman, S.R., Sojitra, S., Stead, M., Washington, E., Scott Glenn, A., Chowdhury, S., Evans, B., Hammonds, J., Hillerich, B., Love, J., Seidel, R.D., Imker, H.J., Armstrong, R.N., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4iem: Human apurinic/apyrimidinic endonuclease (APE1) with product DNA and Mg2+
Classification: HYDROLASE, LYASE/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3936 Å
Deposited: 2012-12-13
Authors: Tsutakawa, S.E., Mol, C.D., Arvai, A.S., Tainer, J.A.
PDB entry 4ien: Crystal Structure of Acyl-CoA Hydrolase from Neisseria meningitidis FAM18
Classification: HYDROLASE
Source organism: Neisseria meningitidis
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2012-12-13
Authors: Khandokar, Y.B., Forwood, J.K.
PDB entry 4ieo: unliganded Cysteine Dioxygenase at pH 4.0 in the presence of Cys
Classification: OXIDOREDUCTASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2012-12-13
Authors: Driggers, C.M., Cooley, R.B., Karplus, P.A.
PDB entry 4iep: unliganded Cysteine Dioxygenase at pH 4.5 in the presence of Cys
Classification: OXIDOREDUCTASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2012-12-13
Authors: Driggers, C.M., Cooley, R.B., Karplus, P.A.
PDB entry 4ieq: unliganded Cysteine Dioxygenase at pH 5.0 in the presence of Cys
Classification: OXIDOREDUCTASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.396 Å
Deposited: 2012-12-13
Authors: Driggers, C.M., Cooley, R.B., Karplus, P.A.
PDB entry 4ier: Cys-persulfenate bound Cysteine Dioxygenase at pH 5.5 in the presence of Cys
Classification: OXIDOREDUCTASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2012-12-13
Authors: Driggers, C.M., Cooley, R.B., Karplus, P.A.
PDB entry 4ies: Cys-persulfenate bound Cysteine Dioxygenase at pH 6.2 in the presence of Cys
Classification: OXIDOREDUCTASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2012-12-13
Authors: Driggers, C.M., Cooley, R.B., Sankaran, B., Karplus, P.A.
PDB entry 4iet: Cys-persulfenate bound Cysteine Dioxygenase at pH 6.8 in the presence of Cys
Classification: OXIDOREDUCTASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2012-12-13
Authors: Driggers, C.M., Cooley, R.B., Karplus, P.A.
PDB entry 4ieu: Cys-persulfenate bound Cysteine Dioxygenase at pH 7.0 in the presence of Cys
Classification: OXIDOREDUCTASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.25 Å
Deposited: 2012-12-13
Authors: Driggers, C.M., Cooley, R.B., Karplus, P.A.
PDB entry 4iev: Cys-only bound Cysteine Dioxygenase at pH 8.0 in the presence of Cys
Classification: OXIDOREDUCTASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2012-12-13
Authors: Driggers, C.M., Cooley, R.B., Karplus, P.A.
PDB entry 4iew: Cys-only bound Cysteine Dioxygenase at pH 9.0 in the presence of Cys
Classification: OXIDOREDUCTASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2012-12-13
Authors: Driggers, C.M., Cooley, R.B., Karplus, P.A.
PDB entry 4iex: unliganded room-temp Cysteine Dioxygenase at pH 6.2
Classification: OXIDOREDUCTASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2012-12-13
Authors: Driggers, C.M., Cooley, R.B., Karplus, P.A.