LiteFold/PDB huggingface dataset:
PDB entry 5tlf: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the Constrained WAY Derivative, 4-(2-(3-methylbut-2-en-1-yl)-7-(trifluoromethyl)-2H-indazol-3-yl)benzene-1,3-diol
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.204 Å
Deposited: 2016-10-11
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tlg: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with (E)-4,4''-dihydroxy-3'-((hydroxyiminio)methyl)-[1,1':2',1''-terphenyl]-4'-olate
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.228 Å
Deposited: 2016-10-11
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tlh: Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 2-naphthol 6-bisphosphonate
Classification: LYASE/INHIBITOR
Source organism: Oryctolagus cuniculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.204 Å
Deposited: 2016-10-11
Authors: Heron, P.W., Sygusch, J.
PDB entry 5tli: THERMOLYSIN (60% ISOPROPANOL SOAKED CRYSTALS)
Classification: HYDROLASE
Source organism: Bacillus thermoproteolyticus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 1998-10-29
Authors: English, A.C., Done, S.H., Groom, C.R., Hubbard, R.E.
PDB entry 5tlj: COMPLEX BETWEEN HUMAN CD27 AND FAB FRAGMENTS OF ANTIBODIES M2177 AND M2191
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Mus musculus, Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.5 Å
Deposited: 2016-10-11
Authors: Teplyakov, A., Obmolova, G., Malia, T., Gilliland, G.L.
PDB entry 5tlk: COMPLEX BETWEEN HUMAN CD27 AND FAB FRAGMENTS OF ANTIBODIES M2177 AND H2191
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Mus musculus, Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2016-10-11
Authors: Teplyakov, A., Obmolova, G., Malia, T., Gilliland, G.L.
PDB entry 5tll: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with (E)-2-chloro-4'-hydroxy-4-((hydroxyiminio)methyl)-[1,1'-biphenyl]-3-olate
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.423 Å
Deposited: 2016-10-11
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tlm: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 4,4',4''-(thiophene-2,3,5-triyl)triphenol
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.497 Å
Deposited: 2016-10-11
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tln: BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
Classification: HYDROLASE (METALLOPROTEINASE)
Source organism: Bacillus thermoproteolyticus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 1982-02-08
Authors: Matthews, B.W., Holmes, M.A.
PDB entry 5tlo: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with a Squaric Acid-linked Dimeric Estrogen
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.28 Å
Deposited: 2016-10-11
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tlp: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS-BSC Analog, 3-fluorophenyl (1R,2R,4S)-5-(4-hydroxyphenyl)-6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate and 3-methyl-6-phenyl-3H-imidazo[4,5-b]pyridin-2-amine
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.08 Å
Deposited: 2016-10-11
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tlq: Model structure of the oxidized PaDsbA1 and 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine complex
Classification: OXIDOREDUCTASE
Source organism: Pseudomonas aeruginosa
Experimental method: SOLUTION NMR
Deposited: 2016-10-11
Authors: Mohanty, B., Rimmer, K.A., McMahon, R.M., Headey, S.J., Vazirani, M., Shouldice, S.R., Coincon, M., Tay, S., Morton, C.J., Simpson, J.S., Martin, J.L., Scanlon, M.S.
PDB entry 5tlr: Solution NMR structure of gHwTx-IV
Classification: TOXIN
Experimental method: SOLUTION NMR
Deposited: 2016-10-11
Authors: Agwa, A.J., Schroeder, C.I.
PDB entry 5tls: 2.4 Angstrom Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with DZ2002 and NAD
Classification: HYDROLASE
Source organism: Cryptosporidium parvum (strain Iowa II)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2016-10-11
Authors: Minasov, G., Shuvalova, L., Kiryukhina, O., Dubrovska, I., Bishop, B., Kwon, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5tlt: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with octane-1,8-diyl bis(2,3-bis(4-hydroxyphenyl)pentanoate)
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.903 Å
Deposited: 2016-10-12
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tlu: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the PEG-linked Dimeric Estrogen, EE2-(eg)6-EE2-amine
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.223 Å
Deposited: 2016-10-12
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tlv: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 4,4'-(thiophene-2,3-diyl)bis(3-fluorophenol)
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.323 Å
Deposited: 2016-10-12
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tlw: Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 1-phosphate-benzene 4-bisphosphonate
Classification: LYASE/INHIBITOR
Source organism: Oryctolagus cuniculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.29 Å
Deposited: 2016-10-12
Authors: Heron, P.W., Sygusch, J.
PDB entry 5tlx: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 3,4-bis(4-hydroxyphenyl)thiophene 1,1-dioxide
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.103 Å
Deposited: 2016-10-12
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tly: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 3,4-bis(2-fluoro-4-hydroxyphenyl)thiophene 1,1-dioxide
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.143 Å
Deposited: 2016-10-12
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tlz: Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor naphthalene 2,6-bisphosphate
Classification: LYASE/INHIBITOR
Source organism: Oryctolagus cuniculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.97 Å
Deposited: 2016-10-12
Authors: Heron, P.W., Sygusch, J.
PDB entry 5tm0: Solution NMR structures of two alternative conformations of E. coli tryptophan repressor in dynamic equilibrium
Classification: TRANSCRIPTION
Source organism: Escherichia coli O157:H7
Experimental method: SOLUTION NMR
Deposited: 2016-10-12
Authors: Harish, B., Swapna, G.V.T., Kornhaber, G.J., Montelione, G.T., Carey, J., Northeast Structural Genomics Consortium (NESG)
PDB entry 5tm1: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 2,5-bis(2-fluoro-4-hydroxyphenyl)thiophene 1-oxide
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.231 Å
Deposited: 2016-10-12
Authors: Nwachukwu, J.C., Wright, N.J., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tm2: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 2,5-bis(2-chloro-4-hydroxyphenyl)thiophene 1-oxide
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.603 Å
Deposited: 2016-10-12
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tm3: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 2,3-bis(2-chloro-4-hydroxyphenyl)thiophene 1-oxide
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.194 Å
Deposited: 2016-10-12
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tm4: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS-ASC Analog, 5-(4-((1R,4S,6R)-6-((3-chlorophenoxy)sulfonyl)-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl)phenoxy)pentanoic acid
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2016-10-12
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tm5: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS-ASC compound, 5-(4-((1R,4S,6R)-6-((4-bromophenoxy)sulfonyl)-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl)phenoxy)pentanoic acid
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.24 Å
Deposited: 2016-10-12
Authors: Nwachukwu, J.C., Wright, N.J., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tm6: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS-ASC compound, 6-(4-((1R,4S,6R)-6-((4-bromophenoxy)sulfonyl)-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl)phenoxy)hexanoic acid
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.542 Å
Deposited: 2016-10-12
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tm7: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS-ASC compound, 7-(4-((1R,4S,6R)-6-((3-chlorophenoxy)sulfonyl)-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl)phenoxy)heptanoic acid
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2016-10-12
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tm8: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS-ASC compound, 7-(4-((1R,4S,6R)-6-((4-bromophenoxy)sulfonyl)-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl)phenoxy)heptanoic acid
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.99 Å
Deposited: 2016-10-12
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tm9: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS-ASC Analog, (E)-3-(4-((1R,4S,6R)-6-((3-chlorophenoxy)sulfonyl)-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl)phenyl)acrylic acid
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2016-10-12
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tma: Zymomonas mobilis pyruvate decarboxylase mutant PDC-2.3
Classification: CELL ADHESION
Source organism: Zymomonas mobilis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.67 Å
Deposited: 2016-10-12
Authors: Alahuhta, P.M., Lunin, V.V.
PDB entry 5tmb: Crystal structure of Os79 from O. sativa in complex with UDP.
Classification: TRANSFERASE
Source organism: Oryza sativa subsp. japonica
Experimental method: X-RAY DIFFRACTION
Resolution: 2.34 Å
Deposited: 2016-10-12
Authors: Wetterhorn, K.M., Newmister, S.A., Caniza, R.K., Busman, M., McCormick, S.P., Berthiller, F., Adam, G., Rayment, I.
PDB entry 5tmc: Re-refinement of Thermus thermopiles DNA-directed RNA polymerase structure
Classification: TRANSFERASE
Source organism: Thermus thermophilus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.71 Å
Deposited: 2016-10-12
Authors: Wang, J.
PDB entry 5tmd: Crystal structure of Os79 from O. sativa in complex with U2F and trichothecene.
Classification: TRANSFERASE
Source organism: Oryza sativa subsp. japonica
Experimental method: X-RAY DIFFRACTION
Resolution: 2.19 Å
Deposited: 2016-10-12
Authors: Wetterhorn, K., Newmister, S.A., Caniza, R.K., Busman, M., McCormick, S.P., Berthiller, F., Adam, G., Rayment, I.
PDB entry 5tme: Crystal structure of Os79 from O. sativa in complex with UDP.
Classification: TRANSFERASE
Source organism: Oryza sativa subsp. japonica
Experimental method: X-RAY DIFFRACTION
Resolution: 1.78 Å
Deposited: 2016-10-12
Authors: Wetterhorn, K.M., Newmister, S.A., Caniza, R.K., Busman, M., McCormick, S.P., Berthiller, F., Adam, G., Rayment, I.
PDB entry 5tmf: Re-refinement of thermus thermophilus RNA polymerase
Classification: TRANSFERASE
Source organism: Thermus thermophilus
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2016-10-12
Authors: Wang, J.
PDB entry 5tmg: Optimization of 3,5-Disubstitued Piperidine: Discovery of Non-Peptide mimetics as an Orally Active Renin Inhibitor
Classification: HYDROLASE/HYDROLASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2016-10-12
Authors: Snell, G.P., Behnke, C.A., Okada, K., Hideyuki, O., Sang, B.C., Lane, W.
PDB entry 5tmh: Structure of Zika virus NS5
Classification: VIRAL PROTEIN
Source organism: Zika virus (strain Mr 766)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.278 Å
Deposited: 2016-10-12
Authors: Wang, B., Tan, X., Song, J.
PDB entry 5tmk: Optimization of 3,5-Disubstitued Piperidine: Discovery of Non-Peptide mimetics as an Orally Active Renin Inhibitor
Classification: HYDROLASE/HYDROLASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.65 Å
Deposited: 2016-10-13
Authors: Snell, G.P., Behnke, C.A., Okada, K., Hideyuki, O., Sang, B.C., Lane, W.
PDB entry 5tml: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS-ASC compound, (E)-6-(4-((1R,4S,6R)-6-((3-chlorophenoxy)sulfonyl)-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl)phenyl)hex-5-enoic acid
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tmm: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS-ASC analog, (E)-6-(4-((1R,4S,6R)-6-((4-bromophenoxy)sulfonyl)-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl)phenyl)hex-5-enoic acid
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tmn: Slow-and fast-binding inhibitors of thermolysin display different modes of binding. crystallographic analysis of extended phosphonamidate transition-state analogues
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Bacillus thermoproteolyticus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 1987-06-29
Authors: Holden, H.M., Tronrud, D.E., Monzingo, A.F., Weaver, L.H., Matthews, B.W.
PDB entry 5tmo: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the Arene Core OBHS derivative, phenyl 4,4''-dihydroxy-[1,1':2',1''-terphenyl]-4'-sulfonate
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.172 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tmp: COMPLEX OF E. COLI THYMIDYLATE KINASE WITH THE BISUBSTRATE INHIBITOR AZTP5A
Classification: TRANSFERASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 1998-09-01
Authors: Lavie, A., Ostermann, N., Schlichting, I.
PDB entry 5tmq: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the Arene Core OBHS derivative, 4-bromophenyl 4,4''-dihydroxy-[1,1':2',1''-terphenyl]-4'-sulfonate
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.24 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tmr: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the Cyclofenil-ASC derivative, ethyl (E)-3-(4-(cyclohexylidene(4-hydroxyphenyl)methyl)phenyl)acrylate
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.296 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tms: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the Cyclofenil-ASC derivative, ethyl (E)-3-(4-(bicyclo[3.3.1]nonan-9-ylidene(4-hydroxyphenyl)methyl)phenyl)acrylate
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.24 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tmt: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 4,4'-((1,3-dihydro-2H-inden-2-ylidene)methylene)diphenol
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.051 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tmu: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 4,4'-(cycloheptylidenemethylene)diphenol
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.429 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tmv: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS analog, 4-iodophenyl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.38 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tmw: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS derivative, 4-acetamidophenyl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.286 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tmx: Solution Structure of SinI, antagonist to the master biofilm-regulator SinR in Bacillus subtilis
Classification: TRANSCRIPTION REGULATOR
Source organism: Bacillus subtilis (strain 168)
Experimental method: SOLUTION NMR
Deposited: 2016-10-13
Authors: Draughn, G.L., Bobay, B.G., Stowe, S.D., Thompson, R.J., Cavanagh, J.
PDB entry 5tmz: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the estradiol derivative, (8S,9S,13S,14S,17S)-16-(3-methoxybenzyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.207 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tn0: Solution Structure of the N-terminal DNA-binding domain of the master biofilm-regulator SinR from Bacillus subtilis
Classification: TRANSCRIPTION
Source organism: Bacillus subtilis (strain 168)
Experimental method: SOLUTION NMR
Deposited: 2016-10-13
Authors: Draughn, G.L., Bobay, B.G., Stowe, S.D., Thompson, R.J., Cavanagh, J.
PDB entry 5tn1: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the estradiol derivative, (8S,9S,13S,14S,E)-17-((4-isopropylphenyl)imino)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-ol
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.055 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tn2: Solution Structure of the C-terminal multimerization domain of the master biofilm-regulator SinR from Bacillus subtilis
Classification: TRANSCRIPTION
Source organism: Bacillus subtilis (strain 168)
Experimental method: SOLUTION NMR
Deposited: 2016-10-13
Authors: Draughn, G.L., Bobay, B.G., Stowe, S.D., Thompson, R.J., Cavanagh, J.
PDB entry 5tn3: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the estradiol derivative, (8S,9S,13S,14S)-17-((4-isopropylphenyl)amino)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-ol
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.543 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tn4: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the ACD-ring estrogen, (S)-5-(4-hydroxy-3,5-dimethylphenyl)-2,3-dihydro-1H-inden-1-ol
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.857 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Erumbi, R., Srinivasan, S., Bruno, N.E., Nowak, J., Izard, T., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tn5: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the AC-ring estrogen, (1S,3aS,5S,7aS)-5-(4-hydroxyphenyl)-7a-methyloctahydro-1H-inden-1-ol
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.892 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tn6: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the Spiro BC-estradiol, (1S,1'S,3a'S,7a'S)-7a'-methyl-1',2,2',3,3',3a',4',6',7',7a'-decahydro-1,5'-spirobi[indene]-1',5-diol
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.091 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tn7: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with (E)-3'-fluoro-4'-hydroxy-3-((hydroxyiminio)methyl)-[1,1'-biphenyl]-4-olate
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.238 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Minutolo, F., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tn8: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with (E)-4'-hydroxy-3-((hydroxyiminio)methyl)-[1,1'-biphenyl]-4-olate
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.652 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Minutolo, F., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tn9: Crystal Structure of the ER-alpha Ligand-binding Domain (L372S,L536S) in Complex with the OBHS-BSC, 4-bromophenyl (1R,2R,4S)-5-(4-hydroxyphenyl)-6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.253 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Sharma, N., Carlson, K.E., Srinivasan, S., Sharma, A., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tnb: Crystal Structure of the ER-alpha Ligand-binding Domain (L372S,L536S) in Complex with the OBHS-BSC, 4-bromophenyl (1R,2R,4S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.08 Å
Deposited: 2016-10-13
Authors: Nwachukwu, J.C., Sharma, N., Carlson, K.E., Srinivasan, S., Sharma, A., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5tnc: REFINED CRYSTAL STRUCTURE OF TROPONIN C FROM TURKEY SKELETAL MUSCLE AT 2.0 ANGSTROMS RESOLUTION
Classification: CONTRACTILE SYSTEM PROTEINS
Source organism: Meleagris gallopavo
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 1988-05-27
Authors: Herzberg, O., James, M.N.G.
PDB entry 5tnd: Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 1,2-Epoxycyclohexane hydrolysis intermediate
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2016-10-14
Authors: Hvorecny, K.L., Madden, D.R.
PDB entry 5tne: Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted cis-Stilbene Oxide hydrolysis intermediate
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2016-10-14
Authors: Hvorecny, K.L., Madden, D.R.
PDB entry 5tnf: Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 19,20-EpDPE hydrolysis intermediate
Classification: hydrolase/hydrolase inhibitor
Source organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2016-10-14
Authors: Hvorecny, K.L., Madden, D.R.
PDB entry 5tng: Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 14,15-EpETE hydrolysis intermediate
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2016-10-14
Authors: Hvorecny, K.L., Madden, D.R.
PDB entry 5tnh: Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 17,18-EpETE hydrolysis intermediate
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2016-10-14
Authors: Hvorecny, K.L., Madden, D.R.
PDB entry 5tni: Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted S-Styrene oxide hydrolysis intermediate
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2016-10-14
Authors: Hvorecny, K.L., Madden, D.R.
PDB entry 5tnj: Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 4-Vinyl-1-cyclohexene 1,2-epoxide hydrolysis intermediate
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2016-10-14
Authors: Hvorecny, K.L., Madden, D.R.
PDB entry 5tnk: Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 1,2-Epoxyoctane hydrolysis intermediate
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2016-10-14
Authors: Hvorecny, K.L., Madden, D.R.
PDB entry 5tnl: Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted (S)-1,2-Epoxyhexane hydrolysis intermediate
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2016-10-14
Authors: Hvorecny, K.L., Madden, D.R.
PDB entry 5tnm: Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted (R)-1,2-Epoxyoctane hydrolysis intermediate
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2016-10-14
Authors: Hvorecny, K.L., Madden, D.R.
PDB entry 5tnn: Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted (S)-1,2-Epoxyoctane hydrolysis intermediate
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2016-10-14
Authors: Hvorecny, K.L., Madden, D.R.
PDB entry 5tno: Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors
Classification: HYDROLASE/HYDROLASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.54 Å
Deposited: 2016-10-14
Authors: Sakurada, I., Endo, T., Hikita, K., Hirabayashi, T., Hosaka, Y., Kato, Y., Maeda, Y., Matsumoto, S., Mizuno, T., Nagasue, H., Nishimura, T., Shimada, S., Shinozaki, M., Taguchi, K., Takeuchi, K., Yokoyama, T., Hruza, A., Reichert, P., Zhang, T., Wood, H.B., Nakao, K., Furusako, S.
PDB entry 5tnp: Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted Styrene oxide hydrolysis intermediate
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2016-10-14
Authors: Hvorecny, K.L., Madden, D.R.
PDB entry 5tnq: Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted (R)-Styrene oxide hydrolysis intermediate
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2016-10-14
Authors: Hvorecny, K.L., Madden, D.R.
PDB entry 5tnr: Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 16,17-EpDPE hydrolysis intermediate
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2016-10-14
Authors: Hvorecny, K.L., Madden, D.R.
PDB entry 5tns: Crystal structure of the D129S mutant of the CFTR inhibitory factor Cif containing 1,2-Epoxycyclohexane
Classification: hydrolase/hydrolase inhibitor
Source organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2016-10-14
Authors: Hvorecny, K.L., Madden, D.R.
PDB entry 5tnt: Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors
Classification: HYDROLASE/HYDROLASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2016-10-14
Authors: Sakurada, I., Endo, T., Hikita, K., Hirabayashi, T., Hosaka, Y., Kato, Y., Maeda, Y., Matsumoto, S., Mizuno, T., Nagasue, A., Nishimura, T., Shimada, S., Shinozaki, M., Taguchi, K., Takeuchi, K., Yokoyama, T., Hruza, A., Reichert, P., Zhang, T., Wood, H.B., Nakao, K., Furusako, S.
PDB entry 5tnu: S. tokodaii XPB II crystal structure at 3.0 Angstrom resolution
Classification: TRANSCRIPTION
Source organism: Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.05 Å
Deposited: 2016-10-14
Authors: DuPrez, K.T., Hilario, E., Wang, I., Fan, L.
PDB entry 5tnv: Crystal Structure of a Xylose isomerase-like TIM barrel Protein from Mycobacterium smegmatis in Complex with Magnesium
Classification: ISOMERASE
Source organism: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.04 Å
Deposited: 2016-10-14
Authors: Cook, W.J., Fedorov, A.A., Fedorov, E.V., Huang, H., Bonanno, J.B., Gerlt, J.A., Almo, S.C.
PDB entry 5tnw: Phospholipase C gamma-1 C-terminal SH2 domain
Classification: HYDROLASE
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2016-10-14
Authors: Wuttke, D.S., McKercher, M.A.
PDB entry 5tnx: Crystal structure of Alcohol dehydrogenase zinc-binding domain protein from Burkholderia ambifaria
Classification: OXIDOREDUCTASE
Source organism: Burkholderia ambifaria (strain MC40-6)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2016-10-15
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5tny: HTRA2 G399S mutant
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2016-10-15
Authors: Merski, M., Barbosa Pereira, P.J., Macedo-Ribeiro, S.
PDB entry 5tnz: HtrA2 S142D mutant
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2016-10-15
Authors: Macedo-Ribeiro, S., Merski, M., Pereira, P.J.B.
PDB entry 5to0: HTRA2 S276C mutant
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2016-10-15
Authors: Merski, M., Barbosa Pereira, P.J., Macedo-Ribeiro, S.
PDB entry 5to1: HtrA2 exposed (L266R, F303A) mutant
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.69 Å
Deposited: 2016-10-15
Authors: Merski, M., Barbosa Pereira, P.J., Macedo-Ribeiro, S.
PDB entry 5to2: Crystal structure of streptavidin with one wild type subunit and three mutated subunits (N23A/S27D/S45A)
Classification: BIOTIN-BINDING PROTEIN
Source organism: Streptomyces avidinii
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2016-10-16
Authors: Zhang, M., Biswas, S., Deng, W., Yu, H.
PDB entry 5to3: Crystal structure of thrombin mutant W215A/E217A fused to EGF456 of thrombomodulin via a 31-residue linker and bound to PPACK
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.34 Å
Deposited: 2016-10-16
Authors: Barranco-Medina, S., Murphy, M., Pelc, L., Chen, Z., Di Cera, E., Pozzi, N.
PDB entry 5to4: Phospholipase C gamma-1 C-terminal SH2 domain, spacegroup P212121
Classification: HYDROLASE
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2016-10-16
Authors: Wuttke, D.S., McKercher, M.A.
PDB entry 5to5: Structure of the TPR oligomerization domain
Classification: CELL CYCLE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2016-10-16
Authors: Pal, K., Xu, Q., Zhou, X.E., Melcher, K., Xu, H.E.
PDB entry 5to6: Structure of the TPR oligomerization domain
Classification: CELL CYCLE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2016-10-16
Authors: Pal, K., Bandyopadhyay, A., Xu, Q., Zhou, X.E., Melcher, K., Xu, H.E.
PDB entry 5to7: Structure of the TPR oligomerization domain
Classification: CELL CYCLE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2016-10-16
Authors: Pal, K., Xu, Q., Zhou, X.E., Melcher, K., Xu, H.E.
PDB entry 5to8: Selectivity switch between FAK and Pyk2: Macrocyclization of FAK inhibitors improves Pyk2 potency
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9849 Å
Deposited: 2016-10-17
Authors: Newby, Z.E.
PDB entry 5toa: Crystal Structure of ER beta bound to Estradiol
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2016-10-17
Authors: Textor, L., Nascimento, A.S., Polikarpov, I.
PDB entry 5tob: Selectivity switch between FAK and Pyk2: Macrocyclization of FAK inhibitors improves Pyk2 potency
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.117 Å
Deposited: 2016-10-17
Authors: Newby, Z.E.
PDB entry 5tod: Transmembrane protein 24 SMP domain
Classification: LIPID TRANSPORT
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.96 Å
Deposited: 2016-10-17
Authors: Lees, J.A., Reinisch, K.M.
PDB entry 5toe: Pim-1 kinase in complex with a 7-azaindole
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.301 Å
Deposited: 2016-10-17
Authors: Mclean, L., Mechin, I., Zhang, Y., Wang, R., Batchelor, J.D.
PDB entry 5tof: Room temperature structure of ubiquitin variant u7ub25
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.12 Å
Deposited: 2016-10-17
Authors: Biel, J.T., Thompson, M.C., Cunningham, C.N., Corn, J.E., Fraser, J.S.
PDB entry 5tog: Room temperature structure of ubiquitin variant u7ub25.2540
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.08 Å
Deposited: 2016-10-17
Authors: Biel, J.T., Thompson, M.C., Cunningham, C.N., Corn, J.E., Fraser, J.S.
PDB entry 5toh: Crystal Structure of the Marburg Virus VP35 Oligomerization Domain I2
Classification: VIRAL PROTEIN
Source organism: Lake Victoria marburgvirus (strain Musoke-80)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.01 Å
Deposited: 2016-10-17
Authors: Bruhn, J.F., Kirchdoerfer, R.N., Tickle, I.J., Bricogne, G., Saphire, E.O.
PDB entry 5toi: Crystal Structure of the Marburg Virus VP35 Oligomerization Domain P4222
Classification: VIRAL PROTEIN
Source organism: Lake Victoria marburgvirus (strain Musoke-80)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.19 Å
Deposited: 2016-10-17
Authors: Bruhn, J.F., Tickle, I.J., Bricogne, G., Saphire, E.O.
PDB entry 5toj: Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-4
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Human respiratory syncytial virus; Lama glama
Experimental method: X-RAY DIFFRACTION
Resolution: 3.3 Å
Deposited: 2016-10-17
Authors: Gilman, M.S.A., Kabeche, S.C., McLellan, J.S.
PDB entry 5tok: Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-L66
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Human respiratory syncytial virus; Lama glama
Experimental method: X-RAY DIFFRACTION
Resolution: 3.8 Å
Deposited: 2016-10-17
Authors: Gilman, M.S.A., Kabeche, S.C., McLellan, J.S.
PDB entry 5tol: CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 COMPLEXED WITH N-(3-((4AS,7AS)-2-AMINO-4,4A,5,6-TETRAHYDRO-7AH-FURO[2,3-D][1,3]THIAZIN-7A-YL)-4-FLUOROPHENYL)-5-BROMO-2-PYRIDINECARBOXAMIDE
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.51 Å
Deposited: 2016-10-18
Authors: Muckelbauer, J.K.
PDB entry 5ton: Crystal structure of AAT H143L mutant
Classification: TRANSFERASE
Source organism: Sus scrofa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2016-10-18
Authors: Mueser, T.C., Dajnowicz, S., Kovalevsky, A.
PDB entry 5too: Crystal structure of alkaline phosphatase PafA T79S, N100A, K162A, R164A mutant
Classification: HYDROLASE
Source organism: Elizabethkingia meningoseptica
Experimental method: X-RAY DIFFRACTION
Resolution: 2.031 Å
Deposited: 2016-10-18
Authors: Lyubimov, A.Y., Sunden, F., AlSadhan, I., Herschlag, D.
PDB entry 5top: Atomic Resolution X-Ray Crystal Structure of a Ruthenocene Conjugated Beta-Lactam Antibiotic in Complex with CTX-M-14 S70G Beta-Lactamase
Classification: HYDROLASE/ANTIBIOTIC
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.18 Å
Deposited: 2016-10-18
Authors: Lewandowski, E.M., Chen, Y.
PDB entry 5toq: High resolution crystal structure of AAT
Classification: TRANSFERASE
Source organism: Sus scrofa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.2 Å
Deposited: 2016-10-18
Authors: Mueser, T.C., Dajnowicz, S., Kovalevsky, A.
PDB entry 5tor: Crystal structure of AAT D222T mutant
Classification: TRANSFERASE
Source organism: Sus scrofa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.35 Å
Deposited: 2016-10-18
Authors: Mueser, T.C., Dajnowicz, S., Kovalevsky, A.
PDB entry 5tos: Botrytis-induced kinase 1 (BIK1) from Arabidopsis thaliana
Classification: TRANSFERASE
Source organism: Arabidopsis thaliana
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2016-10-18
Authors: Hurlburt, N.K., Lal, N.K., Fisher, A.J.
PDB entry 5tot: Crystal structure of AAT H143L:H189L double mutant
Classification: TRANSFERASE
Source organism: Sus scrofa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2016-10-18
Authors: Mueser, T.C., Dajnowicz, S., Kovalevsky, A.
PDB entry 5tou: STRUCTURE OF C-PHYCOCYANIN FROM ARCTIC PSEUDANABAENA SP. LW0831
Classification: PHOTOSYNTHESIS
Source organism: Pseudanabaena sp. lw0831
Experimental method: X-RAY DIFFRACTION
Resolution: 2.04 Å
Deposited: 2016-10-18
Authors: Wang, Q.M., Li, C.Y., Su, H.N., Zhang, Y.Z., Xie, B.B.
PDB entry 5tov: Crystal structure of the inactive form of S-adenosyl-L-homocysteine hydrolase from Thermotoga maritima in binary complex with NADH
Classification: HYDROLASE
Source organism: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2016-10-19
Authors: Czyrko, J., Brzezinski, K.
PDB entry 5tow: Crystal structure of the inactive form of S-adenosyl-L-homocysteine hydrolase from Thermotoga maritima in ternary complex with NADH and Adenosine
Classification: HYDROLASE
Source organism: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2016-10-19
Authors: Czyrko, J., Brzezinski, K.
PDB entry 5toy: X-Ray Crystal Structure of Ruthenocene Conjugated Penicilloate and Penilloate Products in Complex with CTX-M-14 E166A Beta-Lactamase
Classification: HYDROLASE/ANTIBIOTIC
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.3 Å
Deposited: 2016-10-19
Authors: Lewandowski, E.M., Chen, Y.
PDB entry 5toz: JAK3 with covalent inhibitor PF-06651600
Classification: TRANSFERASE/TRANSFERASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2016-10-19
Authors: Vajdos, F.F.
PDB entry 5tp0: Human mesotrypsin in complex with diminazene
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.25 Å
Deposited: 2016-10-19
Authors: Kayode, O., Soares, A., Radisky, E.S.
PDB entry 5tp1: The structure of the C-terminus of virulence protein IncE from Chlamydia trachomatis bound to Mus musculus SNX5-PX domain
Classification: PROTEIN TRANSPORT
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.31 Å
Deposited: 2016-10-19
Authors: Rosenberg, O., Czudnochowski, N.
PDB entry 5tp3: Crystal structure of the RSV-neutralizing single-domain antibody F-VHH-4
Classification: IMMUNE SYSTEM
Source organism: Lama glama
Experimental method: X-RAY DIFFRACTION
Resolution: 1.874 Å
Deposited: 2016-10-19
Authors: Wrapp, D., Gilman, M.S.A., McLellan, J.S.
PDB entry 5tp4: Crystal structure of a hydantoinase/carbamoylase family amidase from Burkholderia ambifaria
Classification: HYDROLASE
Source organism: Burkholderia ambifaria (strain MC40-6)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2016-10-19
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5tp5: Solution structure of the calcium deficient mutant calmodulin CaM1234
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: SOLUTION NMR
Deposited: 2016-10-19
Authors: Piazza, M., Dieckmann, T., Guillemette, J.G.
PDB entry 5tp6: Solution structure of the CaM34 with the iNOS CaM binding domain peptide
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: SOLUTION NMR
Deposited: 2016-10-19
Authors: Piazza, M., Dieckmann, T., Guillemette, J.G.
PDB entry 5tp9: Structure of the human GluN1/GluN2A LBD in complex with compound 2 (GNE9178)
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2016-10-20
Authors: Wallweber, H.J.A., Lupardus, P.J.
PDB entry 5tpa: Structure of the human GluN1/GluN2A LBD in complex with compound 9 (GNE3500)
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.48 Å
Deposited: 2016-10-20
Authors: Wallweber, H.J.A., Lupardus, P.J.
PDB entry 5tpb: Binding domain of BoNT/A complexed with ganglioside variant
Classification: HYDROLASE
Source organism: Clostridium botulinum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2016-10-20
Authors: Berntsson, R.P.-A., Svensson, L.M., Stenmark, P.