LiteFold/PDB huggingface dataset:
PDB entry 6ndi: Crystal Structure of the Sugar Binding Domain of LacI Family Protein from Klebsiella pneumoniae
Classification: SUGAR BINDING PROTEIN
Source organism: Klebsiella pneumoniae subsp. pneumoniae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2018-12-13
Authors: Minasov, G., Shuvalova, L., Wawrzak, Z., Kiryukhina, O., Dubrovska, I., Anderson, W.F., Satchell, K.J.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 6ndj: Crystal structure of human NLRP6 PYD domain with MBP fusion
Classification: SIGNALING PROTEIN
Source organism: Escherichia coli; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.27 Å
Deposited: 2018-12-13
Authors: Shen, C., Fu, T.M., Wu, H.
PDB entry 6ndk: Structure of ASLSufA6 A37.5 bound to the 70S A site
Classification: RIBOSOME
Source organism: Escherichia coli; Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579); Thermus thermophilus HB8; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.64 Å
Deposited: 2018-12-13
Authors: Nguyen, H.T., Hoffer, E.D., Dunham, C.M.
PDB entry 6ndl: Crystal structure of Staphylococcus aureus biotin protein ligase in complex with a sulfonamide inhibitor
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2018-12-13
Authors: Marshall, A.C., Polyak, S.W., Bruning, J.B., Lee, K.
PDB entry 6ndn: Crystal Structure of Selenocysteine Lyase from Escherichia coli
Classification: LYASE
Source organism: Escherichia coli UMEA 3718-1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.768 Å
Deposited: 2018-12-14
Authors: Scortecci, J.F., Brandao-Neto, J., Pereira, H.M., Thiemann, O.H.
PDB entry 6ndo: Crystal structure of the dark-adapted full-length bacteriophytochrome XccBphP mutant L193N from Xanthomonas campestris
Classification: SIGNALING PROTEIN
Source organism: Xanthomonas campestris pv. campestris (strain 8004)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.58 Å
Deposited: 2018-12-14
Authors: Otero, L.H., Sirigu, S., Klinke, S., Rinaldi, J., Conforte, V., Malamud, F., Goldbaum, F.A., Chavas, L., Bonomi, H.R.
PDB entry 6ndp: Crystal structure of the dark-adapted full-length bacteriophytochrome XccBphP mutant L193Q from Xanthomonas campestris
Classification: SIGNALING PROTEIN
Source organism: Xanthomonas campestris pv. campestris (strain 8004)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.89 Å
Deposited: 2018-12-14
Authors: Otero, L.H., Sirigu, S., Klinke, S., Rinaldi, J., Conforte, V., Malamud, F., Goldbaum, F.A., Chavas, L., Bonomi, H.R.
PDB entry 6ndq: Crystal structure of a LPMO from Kitasatospora papulosa
Classification: OXIDOREDUCTASE
Source organism: [Kitasatospora] papulosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.601 Å
Deposited: 2018-12-14
Authors: Correa, T.L.C., Tomazini Jr., A., Murakami, M.T.
PDB entry 6ndr: Crystal structure of dTDP-6-deoxy-D-glucose-3,5-epimerase RmlC from Legionella pneumophila Philadelphia 1 in complex with dTDP-4-KETO-L-RHAMNOSE
Classification: SUGAR BINDING PROTEIN
Source organism: Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2018-12-14
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 6nds: Structure of an HMG-CoA lyase from Acenitobacter baumannii in complex with coenzyme A and 3-methylmalate
Classification: LYASE
Source organism: Acinetobacter baumannii
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2018-12-14
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 6ndt: Dehydroalanine intermediate of the FlgE D2 domain
Classification: MOTOR PROTEIN
Source organism: Treponema denticola
Experimental method: X-RAY DIFFRACTION
Resolution: 1.424 Å
Deposited: 2018-12-14
Authors: Lynch, M.J., Crane, B.R.
PDB entry 6ndu: Structure of human PACRG-MEIG1 complex
Classification: STRUCTURAL PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2018-12-14
Authors: Khan, N., Croteau, N., Pelletier, D., Veyron, S., Trempe, J.F.
PDB entry 6ndv: FlgE D2 domain K336A mutant
Classification: MOTOR PROTEIN
Source organism: Treponema denticola
Experimental method: X-RAY DIFFRACTION
Resolution: 1.502 Å
Deposited: 2018-12-14
Authors: Lynch, M.J., Crane, B.R.
PDB entry 6ndw: Crystal structure of the wild type D2 domain (A168-T344) of the flagellar hook protein FlgE from Treponema denticola
Classification: MOTOR PROTEIN
Source organism: Treponema denticola
Experimental method: X-RAY DIFFRACTION
Resolution: 1.725 Å
Deposited: 2018-12-14
Authors: Lynch, M.J., Crane, B.R.
PDB entry 6ndx: Lysinoalanine cross-linked FlgE dimer from Treponema denticola
Classification: MOTOR PROTEIN
Source organism: Treponema denticola
Experimental method: X-RAY DIFFRACTION
Resolution: 3.04 Å
Deposited: 2018-12-14
Authors: Lynch, M.J., Crane, B.R.
PDB entry 6ndy: Vps4 with Cyclic Peptide Bound in the Central Pore
Classification: TRANSPORT PROTEIN/PEPTIDE
Source organism: Saccharomyces cerevisiae; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.6 Å
Deposited: 2018-12-14
Authors: Han, H., Fulcher, J.M., Dandey, V.P., Sundquist, W.I., Kay, M.S., Shen, P., Hill, C.P.
PDB entry 6ndz: Designed repeat protein in complex with Fz8
Classification: BIOSYNTHETIC PROTEIN/SIGNALING PROTEIN
Source organism: Escherichia coli; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.264 Å
Deposited: 2018-12-14
Authors: Miao, Y., Jude, K.M., Garcia, K.C.
PDB entry 6ne0: Structure of double-stranded target DNA engaged Csy complex from Pseudomonas aeruginosa (PA-14)
Classification: IMMUNE SYSTEM/RNA
Source organism: Pseudomonas aeruginosa UCBPP-PA14; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.4 Å
Deposited: 2018-12-15
Authors: Chowdhury, S., Rollins, M.F., Carter, J., Golden, S.M., Miettinen, H.M., Santiago-Frangos, A., Faith, D., Lawrence, M.C., Wiedenheft, B., Lander, G.C.
PDB entry 6ne1: Designed repeat protein in complex with Fz4
Classification: BIOSYNTHETIC PROTEIN/SIGNALING PROTEIN
Source organism: Homo sapiens; Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.011 Å
Deposited: 2018-12-15
Authors: Miao, Y., Jude, K.M., Garcia, K.C.
PDB entry 6ne2: Designed repeat protein in complex with Fz7
Classification: BIOSYNTHETIC PROTEIN/SIGNALING PROTEIN
Source organism: Escherichia coli; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.299 Å
Deposited: 2018-12-15
Authors: Miao, Y., Jude, K.M., Garcia, K.C.
PDB entry 6ne3: Cryo-EM structure of singly-bound SNF2h-nucleosome complex with SNF2h bound at SHL-2
Classification: DNA BINDING PROTEIN/DNA
Source organism: Homo sapiens; Xenopus laevis
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.9 Å
Deposited: 2018-12-16
Authors: Armache, J.-P., Gamarra, N., Johnson, S.L., Leonard, J.D., Wu, S., Narlikar, G.N., Cheng, Y.
PDB entry 6ne4: Designed repeat protein specifically in complex with Fz7CRD
Classification: BIOSYNTHETIC PROTEIN/SIGNALING PROTEIN
Source organism: Escherichia coli; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.648 Å
Deposited: 2018-12-16
Authors: Miao, Y., Jude, K.M., Garcia, K.C.
PDB entry 6ne5: Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors that Demonstrate in vivo Activity in Mouse Xenograft Models of Human Cancer
Classification: APOPTOSIS
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2018-12-17
Authors: Zhao, B.
PDB entry 6ne6: Crystal Structure of heterotrimeric G-protein alpha subunit Galpha7 from Naegleria fowleri
Classification: CELL CYCLE
Source organism: Naegleria fowleri
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2018-12-17
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 6ne7: Structure of G810A mutant of RET protein tyrosine kinase domain.
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.99 Å
Deposited: 2018-12-17
Authors: Terzyan, S.S., Shen, T., Wu, J., Mooers, B.H.M.
PDB entry 6ne8: Solution Structure of the Thioredoxin-like Domain of Arabidopsis NCP (NUCLEAR CONTROL OF PEP ACTIVITY)
Classification: PLANT PROTEIN
Source organism: Arabidopsis thaliana
Experimental method: SOLUTION NMR
Deposited: 2018-12-17
Authors: Liu, J., Chen, M., Zhou, P.
PDB entry 6ne9: Bacteroides intestinalis acetyl xylan esterase (BACINT_01039)
Classification: HYDROLASE
Source organism: Bacteroides intestinalis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.738 Å
Deposited: 2018-12-17
Authors: Koropatkin, N.M., Pereira, G.V., Cann, I.
PDB entry 6nea: Human Acetylcholinesterase in complex with reactivator, HLo7
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.419 Å
Deposited: 2018-12-17
Authors: Bester, S.M., McGuire, J., Height, J.J., Pegan, S.D.
PDB entry 6neb: MYC Promoter G-Quadruplex with 1:6:1 loop length
Classification: DNA
Experimental method: SOLUTION NMR
Deposited: 2018-12-17
Authors: Dickerhoff, J., Onel, B., Chen, L., Chen, Y., Yang, D.
PDB entry 6nec: STRUCTURE OF RET PROTEIN TYROSINE KINASE DOMAIN IN COMPLEX WITH NINTEDANIB
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.87 Å
Deposited: 2018-12-17
Authors: Terzyan, S.S., Shen, T., Wu, J., Mooers, B.H.M.
PDB entry 6nee: Crystal structure of a reconstructed ancestor of Triosephosphate isomerase from eukaryotes
Classification: ISOMERASE
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2018-12-17
Authors: Rodriguez-Romero, A., Schulte-Sasse, M., Fernandez-Velasco, D.A.
PDB entry 6nef: Outer Membrane Cytochrome S Filament from Geobacter Sulfurreducens
Classification: PROTEIN FIBRIL
Source organism: Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.4 Å
Deposited: 2018-12-17
Authors: Filman, D.J., Marino, S.F., Ward, J.E., Yang, L., Mester, Z., Bullitt, E., Lovley, D.R., Strauss, M.
PDB entry 6neg: N191D, F205S mutant of scoulerine-9-O methyltransferase from Thalictrum flavum complexed with S-ADENOSYL-L-HOMOCYSTEINE
Classification: BIOSYNTHETIC PROTEIN
Source organism: Thalictrum flavum subsp. glaucum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2018-12-17
Authors: Valentic, T.R., Smolke, C.D., Payne, J.T.
PDB entry 6neh: N191D, F205S mutant of scoulerine 9-O-methyltransferase from Thalictrum flavum complexed with (13aS)-3,10-dimethoxy-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline-2,9-diol and S-ADENOSYL-L-HOMOCYSTEINE
Classification: BIOSYNTHETIC PROTEIN
Source organism: Thalictrum flavum subsp. glaucum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.52 Å
Deposited: 2018-12-17
Authors: Valentic, T.R., Smolke, C.D., Payne, J.T.
PDB entry 6nei: Scoulerine 9-O-methyltransferase from Thalictrum flavum
Classification: TRANSFERASE
Source organism: Thalictrum flavum subsp. glaucum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2018-12-17
Authors: Valentic, T.R., Smolke, C.D., Payne, J.T.
PDB entry 6nej: scoulerine 9-O-methyltransferase from Thalictrum flavum complexed (13aS)-3,10-dimethoxy-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline-2,9-diol and with S-ADENOSYL-L-HOMOCYSTEINE
Classification: BIOSYNTHETIC PROTEIN
Source organism: Thalictrum flavum subsp. glaucum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2018-12-17
Authors: Valentic, T.R., Smolke, C.D., Payne, J.T.
PDB entry 6nek: Crystal structure of a consensus PDZ domain
Classification: DE NOVO PROTEIN
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 1.63 Å
Deposited: 2018-12-17
Authors: Sun, Y.J., Gakhar, L., Fuentes, E.J.
PDB entry 6nel: 4-(2-(4-fluorophenyl)-5-hydroxy-6-oxo-1,6-dihydropyridin-3-yl)benzoic acid bound to influenza 2009 pH1N1 endonuclease
Classification: VIRAL PROTEIN/INHIBITOR
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2018-12-17
Authors: Bauman, J.D., Arnold, E.
PDB entry 6nem: 3-hydroxy-5-[(naphthalen-1-yl)methyl]-6-[4-(1H-tetrazol-5-yl)phenyl]pyridin-2(1H)-one bound to influenza 2009 pH1N1 endonuclease
Classification: VIRAL PROTEIN/INHIBITOR
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2018-12-17
Authors: Bauman, J.D., Arnold, E.
PDB entry 6nen: Catalytic domain of Proteus mirabilis ScsC
Classification: OXIDOREDUCTASE
Source organism: Proteus mirabilis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.151 Å
Deposited: 2018-12-17
Authors: Kurth, F., Furlong, E.J., Premkumar, L., Martin, J.L.
PDB entry 6neo: Crystal structure of PprA filament from Deinococcus radiodurans
Classification: DNA BINDING PROTEIN, PROTEIN FIBRIL
Source organism: Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Experimental method: X-RAY DIFFRACTION
Resolution: 5.94 Å
Deposited: 2018-12-18
Authors: Szabla, R., Junop, M.S., Rok, M.
PDB entry 6nep: Structure of human PACRG-MEIG1 complex
Classification: STRUCTURAL PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.09763 Å
Deposited: 2018-12-18
Authors: Khan, N., Croteau, N., Pelletier, D., Veyron, S., Trempe, J.F.
PDB entry 6neq: Structure of human mitochondrial translation initiation factor 3 bound to the small ribosomal subunit-Class-II
Classification: RIBOSOMAL PROTEIN
Source organism: Bos taurus; Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.32 Å
Deposited: 2018-12-18
Authors: Sharma, M., Koripella, R., Agrawal, R.
PDB entry 6ner: Synthetic Haliangium ochraceum BMC shell
Classification: STRUCTURAL PROTEIN
Source organism: Haliangium ochraceum
Experimental method: X-RAY DIFFRACTION
Resolution: 3.59 Å
Deposited: 2018-12-18
Authors: Sutter, M., McGuire, S., Aussignargues, C., Kerfeld, C.A.
PDB entry 6nes: FAD-dependent monooxygenase TropB from T. stipitatus
Classification: FLAVOPROTEIN
Source organism: Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2018-12-18
Authors: Rodriguez Benitez, A., Tweedy, S.E., Baker Dockrey, S.A., Lukowski, A.L., Wymore, T., Khare, D., Brooks, C.L., Palfey, B.A., Smith, J.L., Narayan, A.R.H.
PDB entry 6net: FAD-dependent monooxygenase TropB from T. stipitatus substrate complex
Classification: FLAVOPROTEIN
Source organism: Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2018-12-18
Authors: Rodriguez Benitez, A., Tweedy, S.E., Baker Dockrey, S.A., Lukowski, A.L., Wymore, T., Khare, D., Brooks, C.L., Palfey, B.A., Smith, J.L., Narayan, A.R.H.
PDB entry 6neu: FAD-dependent monooxygenase TropB from T. stipitatus R206Q variant
Classification: FLAVOPROTEIN
Source organism: Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2018-12-18
Authors: Rodriguez Benitez, A., Tweedy, S.E., Baker Dockrey, S.A., Lukowski, A.L., Wymore, T., Khare, D., Brooks, C.L., Palfey, B.A., Smith, J.L., Narayan, A.R.H.
PDB entry 6nev: FAD-dependent monooxygenase TropB from T. stipitatus Y239F Variant
Classification: FLAVOPROTEIN
Source organism: Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.303 Å
Deposited: 2018-12-18
Authors: Rodriguez Benitez, A., Tweedy, S.E., Baker Dockrey, S.A., Lukowski, A.L., Wymore, T., Khare, D., Palfey, B.A., Smith, J.L., Narayan, A.R.H.
PDB entry 6new: Apo structure of the activated truncation of Vav1
Classification: METAL BINDING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2018-12-18
Authors: Knapp, M.S., Elling, R.A., Ornelas, E.
PDB entry 6nex: Fab fragment of anti-cocaine antibody h2E2
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2018-12-18
Authors: Pokkuluri, P.R., Tan, K.
PDB entry 6ney: Crystal structure of TcBDF5, a bromodomain containing protein from Trypanosoma cruzi
Classification: TRANSCRIPTION
Source organism: Trypanosoma cruzi
Experimental method: X-RAY DIFFRACTION
Resolution: 1.68 Å
Deposited: 2018-12-18
Authors: Loppnau, P., Dong, A., Tempel, W., Lin, Y.H., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Hui, R., Vedadi, M., Harding, R.J., Structural Genomics Consortium (SGC)
PDB entry 6nez: Trypanosoma brucei - BDF5, Tb427tmp.01.5000 A, solved with PF-CBP1
Classification: TRANSCRIPTION
Source organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2018-12-18
Authors: Lin, Y.H., Dong, A., Tempel, W., McAuley, J., Loppnau, P., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Hui, R., Vedadi, M., Harding, R.J., Structural Genomics Consortium (SGC)
PDB entry 6nf0: Nocturnin with bound NADPH substrate
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2018-12-18
Authors: Estrella, M.A., Du, J., Korennykh, A.
PDB entry 6nf1: Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity
Classification: METAL BINDING PROTEIN/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2018-12-18
Authors: Knapp, M.S., Elling, R.A., Ornelas, E.
PDB entry 6nf2: Cryo-EM structure of vaccine-elicited antibody 0PV-c.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Human immunodeficiency virus 1
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.7 Å
Deposited: 2018-12-18
Authors: Gorman, J., Kwong, P.D.
PDB entry 6nf3: Structure of the Monoclinic-3 (Monocln-3) Crystal Form of Human Apolipoprotein C1
Classification: LIPID BINDING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.33 Å
Deposited: 2018-12-18
Authors: McPherson, A., Larson, S.B.
PDB entry 6nf4: Structure of zebrafish Otop1 in nanodiscs
Classification: MEMBRANE PROTEIN
Source organism: Danio rerio
Experimental method: ELECTRON MICROSCOPY
Resolution: 2.98 Å
Deposited: 2018-12-18
Authors: Saotome, K., Lee, W.H., Liman, E.R., Ward, A.B.
PDB entry 6nf5: BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP1 fragmentantigen binding and base-binding RM20A3 fragment antigen binding
Classification: VIRAL PROTEIN/immune system
Source organism: Homo sapiens; Human immunodeficiency virus 1; Macaca mulatta
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.71 Å
Deposited: 2018-12-18
Authors: Ozorowski, G., Torres, J.L., Steichen, J.M., Schief, W.R., Ward, A.B.
PDB entry 6nf6: Structure of chicken Otop3 in nanodiscs
Classification: MEMBRANE PROTEIN
Source organism: Gallus gallus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.32 Å
Deposited: 2018-12-18
Authors: Saotome, K., Lee, W.H., Liman, E.R., Ward, A.B.
PDB entry 6nf7: Crystal Structure of RT1.Aa-Bu31-10
Classification: IMMUNE SYSTEM
Source organism: Rattus norvegicus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2018-12-19
Authors: Gras, S.
PDB entry 6nf8: Structure of human mitochondrial translation initiation factor 3 bound to the small ribosomal subunit -Class I
Classification: RIBOSOMAL PROTEIN
Source organism: Bos taurus; Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.48 Å
Deposited: 2018-12-19
Authors: Sharma, M., Koripella, R., Agrawal, R.
PDB entry 6nf9: Structure of M. spretus Endogenous Virus Element (EVE) Virus-like particle (VLP)
Classification: VIRUS LIKE PARTICLE
Source organism: Mus spretus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.89 Å
Deposited: 2018-12-19
Authors: Callaway, H.M., Subramanian, S.
PDB entry 6nfa: Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity
Classification: SIGNALING PROTEIN/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2018-12-19
Authors: Knapp, M.S., Elling, R.A., Ornelas, E.
PDB entry 6nfc: BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP42 fragmentantigen binding and base-binding RM20A3 fragment antigen binding
Classification: VIRAL PROTEIN
Source organism: Homo sapiens; Human immunodeficiency virus 1; Macaca mulatta
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.43 Å
Deposited: 2018-12-19
Authors: Ozorowski, G., Torres, J.L., Ward, A.B.
PDB entry 6nfd: beta-lactamase SHV-11 from Klebsiella pneumoniae strain NTUH-K2044
Classification: LIGASE
Source organism: Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
Experimental method: X-RAY DIFFRACTION
Resolution: 1.17 Å
Deposited: 2018-12-19
Authors: Osipiuk, J., Welk, L., Endres, M., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 6nfe: Crystal Structure of Ribose-phosphate Pyrophosphokinase from Legionella pneumophila with bound AMP, ADP, and Ribose-5-Phosphate
Classification: LIGASE
Source organism: Legionella pneumophila
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2018-12-19
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 6nff: Structure of X-prolyl dipeptidyl aminopeptidase from Lactobacillus helveticus
Classification: HYDROLASE
Source organism: Lactobacillus helveticus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2018-12-20
Authors: Juers, D.H., Bratt, N.J., Ojennus, D.D.
PDB entry 6nfg: CYCLIC GMP-AMP SYNTHASE in complex with compound 16 inhibitor: 7-hydroxy-N-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.76 Å
Deposited: 2018-12-20
Authors: Hall, J.
PDB entry 6nfh: BTK in complex with inhibitor 8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[(2S)-3-(dimethylamino)-2-hydroxypropoxy]phenyl}amino)-5,8-dihydropteridine-6,7-dione
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2018-12-20
Authors: Mirzadegan, T., Damm-Ganamet, K.L.
PDB entry 6nfi: BTK in complex with inhibitor N-(3-{[(2,6-dimethylphenyl)methyl]amino}-7-methoxyindeno[1,2-c]pyrazol-6-yl)methanesulfonamide
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.41 Å
Deposited: 2018-12-20
Authors: Damm-Ganamet, K.L., Mirzadegan, T.
PDB entry 6nfj: Structure of Beta-Klotho in Complex with FGF19 C-terminal peptide
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens; Lama glama; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.19 Å
Deposited: 2018-12-20
Authors: Kuzina, E., Schlessinger, J., Lee, S.
PDB entry 6nfk: Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B with loop 7 from APOBEC3G bound to iodide
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.86 Å
Deposited: 2018-12-20
Authors: Shi, K., Orellana, K., Aihara, H.
PDB entry 6nfl: Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B with loop 7 from APOBEC3G complexed with 2-HP
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.731 Å
Deposited: 2018-12-20
Authors: Shi, K., Orellana, K., Aihara, H.
PDB entry 6nfm: Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B with loop 7 from APOBEC3G
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.53 Å
Deposited: 2018-12-20
Authors: Shi, K., Aihara, H.
PDB entry 6nfn: Fab fragment of anti-cocaine antibody h2E2 bound to benzoylecgonine
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.63 Å
Deposited: 2018-12-20
Authors: Pokkuluri, P.R., Tan, K.
PDB entry 6nfo: CYCLIC GMP-AMP SYNTHASE in complex with compound 20 inhibitor: 7-hydroxy-N-[(2S)-1-hydroxypropan-2-yl]-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.93 Å
Deposited: 2018-12-20
Authors: Hall, J.
PDB entry 6nfp: 1.7 Angstrom Resolution Crystal Structure of Arginase from Bacillus subtilis subsp. subtilis str. 168
Classification: HYDROLASE
Source organism: Bacillus subtilis (strain 168)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2018-12-20
Authors: Minasov, G., Wawrzak, Z., Evdokimova, E., Grimshaw, S., Kwon, K., Savchenko, A., Satchell, K.J.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 6nfq: CopC from Pseudomonas fluorescens
Classification: METAL BINDING PROTEIN
Source organism: Pseudomonas fluorescens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2018-12-20
Authors: Maher, M.J.
PDB entry 6nfr: CopC from Pseudomonas fluorescens
Classification: METAL BINDING PROTEIN
Source organism: Pseudomonas fluorescens
Experimental method: X-RAY DIFFRACTION
Resolution: 1 Å
Deposited: 2018-12-20
Authors: Maher, M.J.
PDB entry 6nfs: CopC from Pseudomonas fluorescens
Classification: METAL BINDING PROTEIN
Source organism: Pseudomonas fluorescens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2018-12-20
Authors: Maher, M.J.
PDB entry 6nft: Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with (4-oxoquinazolin-3(4H)-yl)acetic acid
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2018-12-20
Authors: Harding, R.J., Mann, M.K., Tempel, W., Bountra, C., Arrowmsmith, C.M., Edwards, A.M., Schapira, M., Structural Genomics Consortium (SGC)
PDB entry 6nfu: Structure of the KcsA-G77A mutant or the 2,4-ion bound configuration of a K+ channel selectivity filter.
Classification: membrane protein, metal transport
Source organism: Mus musculus; Streptomyces lividans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.09 Å
Deposited: 2018-12-20
Authors: Tilegenova, C., Cortes, D.M., Jahovic, N., Hardy, E., Parameswaran, H., Guan, L., Cuello, L.G.
PDB entry 6nfv: Structure of the KcsA-G77C mutant or the 2,4-ion bound configuration of a K+ channel selectivity filter.
Classification: membrane protein, metal transport
Source organism: Mus musculus; Streptomyces lividans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.13 Å
Deposited: 2018-12-20
Authors: Tilegenova, C., Cortes, D.M., Jahovic, N., Hardy, E., Parameswaran, H., Guan, L., Cuello, L.G.
PDB entry 6nfw: Potyvirus viral protein genome linked (VPg) emulates the m7G cap to recruit the eukaryotic translation initiation factor eIF4E
Classification: VIRAL PROTEIN
Source organism: Potato virus Y
Experimental method: SOLUTION NMR
Deposited: 2018-12-21
Authors: Borden, K., Volpon, L., Osborne, M.
PDB entry 6nfx: MBTD1 MBT repeats
Classification: PROTEIN BINDING
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2018-12-21
Authors: Zhang, H., Tempel, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
PDB entry 6nfy: Crystal structure of nonphosphorylated, HPK1 kinase domain in complex with sunitinib in the inactive state.
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.17 Å
Deposited: 2018-12-21
Authors: Johnson, E., McTigue, M., Cronin, C.N.
PDB entry 6nfz: Crystal structure of diphosphorylated HPK1 kinase domain in complex with sunitinib in the active state.
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.966 Å
Deposited: 2018-12-21
Authors: Johnson, E., McTigue, M., Cronin, C.N.
PDB entry 6ng0: Crystal structure of HPK1 kinase domain T165E,S171E phosphomimetic mutant in complex with sunitinib in the inactive state.
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2018-12-21
Authors: Johnson, E., McTigue, M., Cronin, C.N.
PDB entry 6ng1: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-fluoro-5-(3-(methylamino)prop-1-yn-1-yl)phenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ng2: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3-(dimethylamino)prop-1-yn-1-yl)-5-fluorophenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.93 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ng3: Crystal structure of human CD160 and HVEM complex
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.88 Å
Deposited: 2018-12-21
Authors: Liu, W., Bonanno, J., Almo, S.C.
PDB entry 6ng4: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (R)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.776 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ng5: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (R)-6-(3-fluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.96 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ng6: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (S)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.044 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ng7: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-fluoro-5-(2-((2R,4S)-4-fluoro-1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ng8: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ng9: Crystal structure of human CD160
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.954 Å
Deposited: 2018-12-21
Authors: Liu, W., Bonanno, J., Almo, S.C.
PDB entry 6nga: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,6-difluorophenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngb: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5-difluorophenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngc: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5,6-trifluorophenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.998 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngd: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3,4-trifluorophenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6nge: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(2,3-difluoro-5-(3-(methylamino)prop-1-yn-1-yl)phenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.102 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngf: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (R)-6-(2,3-difluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.993 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngg: Crystal structure of human CD160 V58M mutant
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2018-12-21
Authors: Liu, W., Bonanno, J., Almo, S.C.
PDB entry 6ngh: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngi: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(4-methylmorpholin-3-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngj: Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(3-(methylamino)prop-1-yn-1-yl)phenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.756 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngk: Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)prop-1-yn-1-yl)-5-fluorophenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.83 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngl: Structure of rat neuronal nitric oxide synthase heme domain in complex with (R)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.83 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngm: Structure of rat neuronal nitric oxide synthase heme domain in complex with (R)-6-(3-fluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.693 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngn: Structure of rat neuronal nitric oxide synthase heme domain in complex with (S)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngp: Structure of rat neuronal nitric oxide synthase heme domain in complex with (S)-6-(3-fluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.976 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngq: Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2R,4S)-4-fluoropyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngr: Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2R,4S)-4-fluoro-1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.819 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngs: Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngt: Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,6-difluorophenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.942 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngu: Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5-difluorophenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngv: Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5,6-trifluorophenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.829 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngw: Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3,4-trifluorophenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.858 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngx: Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(2,3-difluoro-5-(3-(methylamino)prop-1-yn-1-yl)phenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.773 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngy: Structure of rat neuronal nitric oxide synthase heme domain in complex with (R)-6-(2,3-difluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.928 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6ngz: Structure of rat neuronal nitric oxide synthase heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6nh0: Structure of rat neuronal nitric oxide synthase heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(4-methylmorpholin-3-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.898 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6nh1: Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(3-(methylamino)prop-1-yn-1-yl)phenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.216 Å
Deposited: 2018-12-21
Authors: Chreifi, G., Li, H., Poulos, T.L.
PDB entry 6nh2: Structure of human endothelial nitric oxide synthase heme domain in complex with (R)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.29 Å
Deposited: 2018-12-21
Authors: Chreifi, G., Li, H., Poulos, T.L.
PDB entry 6nh3: Structure of human endothelial nitric oxide synthase heme domain in complex with (S)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.01 Å
Deposited: 2018-12-21
Authors: Chreifi, G., Li, H., Poulos, T.L.
PDB entry 6nh4: Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2R,4S)-4-fluoropyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.27 Å
Deposited: 2018-12-21
Authors: Chreifi, G., Li, H., Poulos, T.L.
PDB entry 6nh5: Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2R,4S)-4-fluoro-1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.959 Å
Deposited: 2018-12-21
Authors: Chreifi, G., Li, H., Poulos, T.L.
PDB entry 6nh6: Structure of the human endothelial nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,6-difluorophenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.189 Å
Deposited: 2018-12-21
Authors: Chreifi, G., Li, H., Poulos, T.L.
PDB entry 6nh7: Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5,6-trifluorophenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2018-12-21
Authors: Chreifi, G., Li, H., Poulos, T.L.
PDB entry 6nh8: Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3,4-trifluorophenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2018-12-21
Authors: Chreifi, G., Li, H., Poulos, T.L.
PDB entry 6nh9: Crystal structure of a human calcium/calmodulin dependent serine protein kinase (CASK) PDZ domain
Classification: PROTEIN BINDING
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2018-12-21
Authors: Sun, Y.J., Gakhar, L., Fuentes, E.J.
PDB entry 6nha: Crystal structure of SYNT001, a human FcRn blocking monoclonal antibody
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.381 Å
Deposited: 2018-12-21
Authors: Blumberg, R.S., Cheung, J., Mahmood, A., Gandhi, A.K.
PDB entry 6nhb: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(5-(2-((2S,4R)-4-ethoxy-1-methylpyrrolidin-2-yl)ethyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.03 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6nhc: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylazetidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.16 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6nhd: Structure of rat neuronal nitric oxide synthase heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylazetidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6nhe: Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(5-(2-((2S,4R)-4-ethoxy-1-methylpyrrolidin-2-yl)ethyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.999 Å
Deposited: 2018-12-21
Authors: Li, H., Poulos, T.L.
PDB entry 6nhf: Structure of human endothelial nitric oxide synthase heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylazetidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.83 Å
Deposited: 2018-12-21
Authors: Chreifi, G., Li, H., Poulos, T.L.
PDB entry 6nhg: Rhodobacter sphaeroides Mitochondrial respiratory chain complex
Classification: OXIDOREDUCTASE
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2018-12-21
Authors: Xia, D., Zhou, F., Esser, L.
PDB entry 6nhh: Rhodobacter sphaeroides bc1 with azoxystrobin
Classification: OXIDOREDUCTASE
Source organism: Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2018-12-21
Authors: Xia, D., Zhou, F., Yu, C.A.
PDB entry 6nhi: Crystal structure of Histidine--tRNA ligase from Elizabethkingia sp. CCUG 26117
Classification: LIGASE
Source organism: Elizabethkingia meningoseptica
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2018-12-21
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 6nhj: Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development
Classification: VIRUS
Source organism: Murine cytomegalovirus (strain Smith)
Experimental method: ELECTRON MICROSCOPY
Resolution: 5 Å
Deposited: 2018-12-22
Authors: Liu, W., Dai, X.H., Jih, J., Chan, K., Trang, P., Yu, X.K., Balogun, R., Mei, Y., Liu, F.Y., Zhou, Z.H.