LiteFold/PDB huggingface dataset:
PDB entry 4tw7: The Fk1 domain of FKBP51 in complex with iFit4
Classification: ISOMERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.25 Å
Deposited: 2014-06-30
Authors: Gaali, S., Kirschner, A., Cuboni, S., Hartmann, J., Kozany, C., Balsevich, G., Namendorf, C., Fernandez-Vizarra, P., Almeida, O.F.X., Ruehter, G., Uhr, M., Schmidt, M.V., Touma, C., Bracher, A., Hausch, F.
PDB entry 4tw8: The Fk1-Fk2 domains of FKBP52 in complex with iFit-FL
Classification: ISOMERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.003 Å
Deposited: 2014-06-30
Authors: Gaali, S., Kirschner, A., Cuboni, S., Hartmann, J., Kozany, C., Balsevich, G., Namendorf, C., Fernandez-Vizarra, P., Almeida, O.F.X., Ruehter, G., Uhr, M., Schmidt, M.V., Touma, C., Bracher, A., Hausch, F.
PDB entry 4tw9: Difluoro-dioxolo-benzoimidazol-benzamides as potent inhibitors of CK1delta and epsilon with nanomolar inhibitory activity on cancer cell proliferation
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2014-06-30
Authors: Richter, J., Bischof, J., Zaja, M., Kohlhof, H., Othersen, O., Vitt, D., Alscher, V., Pospiech, I., Garcia-Reyes, B., Berg, S., Leban, J., Knippschild, U.
PDB entry 4twa: Crystal Structure of Prolyl-tRNA Synthetase (PRS) from Plasmodium falciparum
Classification: LIGASE
Source organism: Plasmodium falciparum
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2014-06-30
Authors: Jain, V., Yogavel, M., Sharma, A.
PDB entry 4twb: Sulfolobus solfataricus ribose-phosphate pyrophosphokinase
Classification: TRANSFERASE
Source organism: Sulfolobus solfataricus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.802 Å
Deposited: 2014-06-30
Authors: Kadziola, A.
PDB entry 4twc: 2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4- carboxamide derivatives as potent inhibitors of CK1d/e
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2014-06-30
Authors: Bischof, J., Leban, L., Zaja, M., Grothey, A., Radunsky, B., Othersen, O., Strobl, S., Vitt, D., Knippschild, U.
PDB entry 4twd: X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with memantine
Classification: TRANSPORT PROTEIN
Source organism: Dickeya chrysanthemi
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2 Å
Deposited: 2014-06-30
Authors: Ulens, C., Spurny, R., Thompson, A.J., Alqazzaz, M., Debaveye, S., Lu, H., Price, K., Villalgordo, J.M., Tresadern, G., Lynch, J.W., Lummis, S.C.R.
PDB entry 4twe: Structure of ligand-free N-acetylated-alpha-linked-acidic-dipeptidase like protein (NAALADaseL)
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2014-06-30
Authors: Tykvart, J., Barinka, C., Lubkowski, J., Sacha, P., Konvalinka, J.
PDB entry 4twf: X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromomemantine
Classification: TRANSPORT PROTEIN
Source organism: Dickeya chrysanthemi
Experimental method: X-RAY DIFFRACTION
Resolution: 3.901 Å
Deposited: 2014-06-30
Authors: Ulens, C., Spurny, R., Thompson, A.J., Alqazzaz, M., Debaveye, S., Lu, H., Price, K., Villalgordo, J.M., Tresadern, G., Lynch, J.W., Lummis, S.C.R.
PDB entry 4twg: The structure of the Molybdopterin biosynthesis Mog protein from Mycobacterium ulcerans
Classification: BIOSYNTHETIC PROTEIN
Source organism: Mycobacterium ulcerans
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2014-06-30
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 4twh: X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) mutant F16'S
Classification: TRANSPORT PROTEIN
Source organism: Dickeya chrysanthemi
Experimental method: X-RAY DIFFRACTION
Resolution: 3.6 Å
Deposited: 2014-06-30
Authors: Ulens, C., Spurny, R., Thompson, A.J., Alqazzaz, M., Debaveye, S., Lu, H., Price, K., Villalgordo, J.M., Tresadern, G., Lynch, J.W., Lummis, S.C.R.
PDB entry 4twi: The structure of Sir2Af1 bound to a succinylated histone peptide
Classification: HYDROLASE
Source organism: Archaeoglobus fulgidus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.79 Å
Deposited: 2014-06-30
Authors: Ringel, A.E., Roman, C., Wolberger, C.
PDB entry 4twj: The structure of Sir2Af2 bound to a myristoylated histone peptide
Classification: HYDROLASE
Source organism: Archaeoglobus fulgidus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2014-06-30
Authors: Ringel, A.E., Roman, C., Wolberger, C.
PDB entry 4twk: Crystal structure of human two pore domain potassium ion channel TREK1 (K2P2.1)
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2014-06-30
Authors: Pike, A.C.W., Dong, Y.Y., Tessitore, A., Goubin, S., Strain-Damerell, C., Mukhopadhyay, S., Kupinska, K., Wang, D., Chalk, R., Berridge, G., Grieben, M., Shrestha, L., Ang, J.H., Mackenzie, A., Quigley, A., Bushell, S.R., Shintre, C.A., Faust, B., Chu, A., Dong, L., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Carpenter, E.P.
PDB entry 4twl: Crystal structure of dioscorin complexed with ascorbate
Classification: PLANT PROTEIN
Source organism: Dioscorea japonica
Experimental method: X-RAY DIFFRACTION
Resolution: 2.11 Å
Deposited: 2014-07-01
Authors: Xue, Y.L., Miyakawa, T., Nakamura, A., Tanokura, M.
PDB entry 4twm: Crystal structure of dioscorin from Dioscorea japonica
Classification: PLANT PROTEIN
Source organism: Dioscorea japonica
Experimental method: X-RAY DIFFRACTION
Resolution: 2.11 Å
Deposited: 2014-07-01
Authors: Xue, Y.L., Miyakawa, T., Nakamura, A., Tanokura, M.
PDB entry 4twn: Human EphA3 Kinase domain in complex with Birb796
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.706 Å
Deposited: 2014-07-01
Authors: Dong, J., Caflisch, A.
PDB entry 4two: Human EphA3 Kinase domain in complex with compound 164
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.047 Å
Deposited: 2014-07-01
Authors: Dong, J., Caflisch, A.
PDB entry 4twp: The crystal structure of human abl1 T315I gatekeeper mutant kinase domain in complex with axitinib
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2014-07-01
Authors: Johnson, E., McTigue, M., Cronin, C.N.
PDB entry 4twr: Structure of UDP-glucose 4-epimerase from Brucella abortus
Classification: ISOMERASE
Source organism: Brucella abortus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2014-07-01
Authors: Horanyi, P.S., Abendroth, J., Lorimer, D., Edwards, T., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 4tws: Gadolinium Derivative of Tetragonal Hen Egg-White Lysozyme at 1.45 A Resolution
Classification: HYDROLASE
Source organism: Gallus gallus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2014-07-01
Authors: Holton, J.M., Classen, S., Frankel, K.A., Tainer, J.A.
PDB entry 4twt: Human TNFa dimer in complex with the semi-synthetic bicyclic peptide M21
Classification: Cytokine/inhibitor
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.85 Å
Deposited: 2014-07-01
Authors: Luzi, S., Kondo, Y., Bernard, E., Stadler, L., Winter, G., Holliger, P.
PDB entry 4twu: Horse heart myoglobin mutant (D44K/D60K/E85K) with Zn-deuteroporphyrin IX
Classification: OXYGEN TRANSPORT
Source organism: Equus caballus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.08 Å
Deposited: 2014-07-02
Authors: Span, I., Rosenzweig, A.C.
PDB entry 4twv: Horse heart myoglobin mutant (K45E/K63E/K96E) with Zn-deuteroporphyrin IX
Classification: OXYGEN TRANSPORT
Source organism: Equus caballus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.06 Å
Deposited: 2014-07-02
Authors: Span, I., Rosenzweig, A.C.
PDB entry 4tww: Structure of SARS-3CL protease complex with a Bromobenzoyl (S,R)-N-decalin type inhibitor
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human SARS coronavirus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.42 Å
Deposited: 2014-07-02
Authors: Akaji, K., Teruya, K., Shimamoto, Y., Sanjho, A., Yamashita, E., Nakagawa, A.
PDB entry 4twy: Structure of SARS-3CL protease complex with a phenylbenzoyl (S,R)-N-decalin type inhibitor
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human SARS coronavirus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2014-07-02
Authors: Akaji, K., Teruya, K., Shimamoto, Y., Sanjho, A., Yamashita, E., Nakagawa, A.
PDB entry 4twz: Crystal Structure Analysis of E Coli. RecA Protein
Classification: RECOMBINATION
Source organism: Escherichia coli K12
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2014-07-02
Authors: Hikima, T., Hiraki, T., Furuse, M., Ikawa, S., Iwasaki, W., Shibata, T., Kamiya, N.
PDB entry 4tx0: The Fk1 domain of FKBP51 in complex with (1S,5S,6R)-10-[(3,5-dichlorophenyl)sulfonyl]-5-(2-methoxyethoxy)-3-(2-methoxyethyl)-3,10-diazabicyclo[4.3.1]decan-2-one
Classification: ISOMERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.03 Å
Deposited: 2014-07-02
Authors: Bischoff, M., Sippel, C., Bracher, A., Hausch, F.
PDB entry 4tx1: The crystal structure of carbohydrate acetylesterase family member from Sinorhizobium meliloti
Classification: HYDROLASE
Source organism: Sinorhizobium meliloti 1021
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2014-07-02
Authors: Kim, K., Kim, S.S., Pandian, R., Ngo, T.D.
PDB entry 4tx2: Crystal structure of the X-domain from teicoplanin biosynthesis
Classification: PROTEIN BINDING
Source organism: Actinoplanes teichomyceticus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2014-07-02
Authors: Peschke, M., Haslinger, K., Cryle, M.J.
PDB entry 4tx3: Complex of the X-domain and OxyB from Teicoplanin Biosynthesis
Classification: OXIDOREDUCTASE
Source organism: Actinoplanes teichomyceticus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2014-07-02
Authors: Peschke, M., Haslinger, K., Cryle, M.J.
PDB entry 4tx4: Crystal Structure of a Single-Domain Cysteine Protease Inhibitor from Cowpea (Vigna unguiculata)
Classification: HYDROLASE INHIBITOR
Source organism: Vigna unguiculata
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2014-07-02
Authors: Pereira, H.M., Valadares, N., Monteiro-Junior, J.E., Carvalho, C.P.S., Grangeiro, T.B.
PDB entry 4tx5: Crystal structure of Smac-DIABLO (in space group P65)
Classification: APOPTOSIS
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2014-07-02
Authors: Milani, M., Mastangelo, E., Cossu, F.
PDB entry 4tx6: AfChiA1 in complex with compound 1
Classification: HYDROLASE
Source organism: Aspergillus fumigatus A1163
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2014-07-02
Authors: van Aalten, D.M.F.
PDB entry 4tx7: Crystal structure of chitinase (GH19) from Vigna unguiculata
Classification: HYDROLASE
Source organism: Vigna unguiculata subsp. sesquipedalis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2014-07-02
Authors: Pereira, H.M., Castro-Landin, P.G., Brandao-Neto, J., Grangeiro, T.B.
PDB entry 4tx8: Crystal Structure of a Family GH18 Chitinase from Chromobacterium violaceum
Classification: HYDROLASE
Source organism: Chromobacterium violaceum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.17 Å
Deposited: 2014-07-02
Authors: Pereira, H.M., Lobo, M.D.P., Brandao-Neto, J., Grangeiro, T.B.
PDB entry 4tx9: Crystal structure of HisAp from Streptomyces sviceus with degraded ProFAR
Classification: ISOMERASE
Source organism: Streptomyces sviceus ATCC 29083
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2014-07-02
Authors: Michalska, K., Verduzco-Castro, E.A., Endres, M., Barona-Gomez, F., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 4txa: Crystal structure of N-terminus of Roquin
Classification: RNA BINDING PROTEIN
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.75 Å
Deposited: 2014-07-03
Authors: Kershaw, N.J., Vinuesa, C.G., Babon, J.J.
PDB entry 4txc: Crystal Structure of DAPK1 kinase domain in complex with a small molecule inhibitor
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.951 Å
Deposited: 2014-07-03
Authors: Sorrell, F.J., Krojer, T., Wilbek, T.S., Skovgaard, T., Berthelsen, J., Dixon-Clarke, S., Chalk, R., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Stromgaard, K., Knapp, S.
PDB entry 4txd: Crystal structure of Thermofilum pendens Csc2
Classification: RNA BINDING PROTEIN
Source organism: Thermofilum pendens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.818 Å
Deposited: 2014-07-03
Authors: Hrle, A., Conti, E.
PDB entry 4txe: ScCTS1 in complex with compound 5
Classification: HYDROLASE
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2014-07-03
Authors: Schuettelkopf, A.W., van Aalten, D.M.F.
PDB entry 4txg: Crystal Structure of a Family GH18 Chitinase from Chromobacterium violaceum
Classification: HYDROLASE
Source organism: Chromobacterium violaceum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2014-07-03
Authors: Pereira, H.M., Teixeira, C.S., Grangeiro, T.B.
PDB entry 4txh: Crystal structure of uridine phosphorylase from Schistosoma mansoni in APO form
Classification: TRANSFERASE
Source organism: Schistosoma mansoni
Experimental method: X-RAY DIFFRACTION
Resolution: 1.892 Å
Deposited: 2014-07-03
Authors: Torini, J., Romanello, L., Marinho, A., Brandao-Neto, J., Cassago, A., DeMarco, R., Pereira, H.M.
PDB entry 4txi: Construct of MICAL-1 containing the monooxygenase and calponin homology domains
Classification: OXIDOREDUCTASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.309 Å
Deposited: 2014-07-03
Authors: Alqassim, S.S., Amzel, L.M., Bianchet, M.A.
PDB entry 4txj: Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with thymidine
Classification: TRANSFERASE
Source organism: Schistosoma mansoni
Experimental method: X-RAY DIFFRACTION
Resolution: 1.662 Å
Deposited: 2014-07-03
Authors: Torini, J., Marinho, A., Romanello, L., Cassago, A., DeMarco, R., Brandao-Neto, J., Pereira, H.M.
PDB entry 4txk: Construct of MICAL-1 containing the monooxygenase and calponin homology domains
Classification: OXIDOREDUCTASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.878 Å
Deposited: 2014-07-03
Authors: Alqassim, S.S., Amzel, L.M., Bianchet, M.A.
PDB entry 4txl: Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with uracil
Classification: TRANSFERASE
Source organism: Schistosoma mansoni
Experimental method: X-RAY DIFFRACTION
Resolution: 1.92 Å
Deposited: 2014-07-03
Authors: Marinho, A., Torini, J., Romanello, L., Cassago, A., DeMarco, R., Brandao-Neto, J., Pereira, H.M.
PDB entry 4txm: Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with thymine
Classification: TRANSFERASE
Source organism: Schistosoma mansoni
Experimental method: X-RAY DIFFRACTION
Resolution: 1.93 Å
Deposited: 2014-07-03
Authors: Marinho, A., Torini, J., Romanello, L., Cassago, A., DeMarco, R., Brandao-Neto, J., Pereira, H.M.
PDB entry 4txn: Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with 5-fluorouracil
Classification: TRANSFERASE
Source organism: Schistosoma mansoni
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2014-07-03
Authors: Marinho, A., Torini, J., Romanello, L., Cassago, A., DeMarco, R., Brandao-Neto, J., Pereira, H.M.
PDB entry 4txo: Crystal structure of the mixed disulfide complex of thioredoxin-like TlpAs(C110S) and copper chaperone ScoIs(C74S)
Classification: OXIDODREDUCTASE/COPPER BINDING PROTEIN
Source organism: Bradyrhizobium diazoefficiens USDA 110
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2014-07-04
Authors: Scharer, M.A., Abicht, H.K., Glockshuber, R., Hennecke, H.
PDB entry 4txp: Crystal structure of LIP5 N-terminal domain
Classification: PROTEIN TRANSPORT
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.01 Å
Deposited: 2014-07-04
Authors: Vild, C.J., Xu, Z.
PDB entry 4txq: Crystal structure of LIP5 N-terminal domain complexed with CHMP1B MIM
Classification: PROTEIN TRANSPORT
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.21 Å
Deposited: 2014-07-04
Authors: Vild, C.J., Xu, Z.
PDB entry 4txr: Crystal structure of LIP5 N-terminal domain complexed with CHMP1B MIM and CHMP5 MIM
Classification: PROTEIN TRANSPORT
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1 Å
Deposited: 2014-07-04
Authors: Vild, C.J., Xu, Z.
PDB entry 4txs: An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Hepatitis C virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.78 Å
Deposited: 2014-07-07
Authors: Shui, W., Yang, C., Lin, J., Chen, X., Qin, S., Chen, S.
PDB entry 4txt: Crystal Structure of a GH48 cellobiohydrolase from Caldicellulosiruptor bescii
Classification: HYDROLASE
Source organism: Caldicellulosiruptor bescii DSM 6725
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2014-07-07
Authors: An, J., Feng, Y.
PDB entry 4txv: Crystal structure of the mixed disulfide intermediate between thioredoxin-like TlpAs(C110S) and subunit II of cytochrome c oxidase CoxBPD (C233S)
Classification: PROTEIN BINDING
Source organism: Bradyrhizobium diazoefficiens; Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2014-07-07
Authors: Quade, N., Abicht, H.K., Hennecke, H., Glockshuber, R.
PDB entry 4txw: Crystal structure of CBM32-4 from the Clostridium perfringens NagH
Classification: carbohydrate-binding module
Source organism: Clostridium perfringens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2014-07-07
Authors: Grondin, J.M., Ficko-Blean, E., Boraston, A.B., Smith, S.P.
PDB entry 4txy: Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase, a prokaryotic cGAS homolog
Classification: TRANSFERASE
Source organism: Vibrio cholerae O1 biovar El Tor str. N16961
Experimental method: X-RAY DIFFRACTION
Resolution: 3.0001 Å
Deposited: 2014-07-07
Authors: Kranzusch, P.J., Lee, A.S.Y., Wilson, S.C., Solovykh, M.S., Vance, R.E., Berger, J.M., Doudna, J.A.
PDB entry 4txz: Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with nonhydrolyzable GTP
Classification: TRANSFERASE
Source organism: Vibrio cholerae O1 biovar El Tor str. N16961
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2014-07-07
Authors: Kranzusch, P.J., Lee, A.S.Y., Wilson, S.C., Solovykh, M.S., Vance, R.E., Berger, J.M., Doudna, J.A.
PDB entry 4ty0: Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with linear intermediate 5' pppA(3',5')pG
Classification: TRANSFERASE
Source organism: Vibrio cholerae O1 biovar El Tor str. N16961
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2014-07-07
Authors: Kranzusch, P.J., Lee, A.S.Y., Wilson, S.C., Solovykh, M.S., Vance, R.E., Berger, J.M., Doudna, J.A.
PDB entry 4ty1: Crystal structure of human Pim-1 kinase in complex with an aminooxadiazole-indole inhibitor.
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2014-07-07
Authors: Mohr, C.
PDB entry 4ty6: Factor XIa in complex with the inhibitor 4-{2-[(1S)-1-({[trans-4-(aminomethyl)cyclohexyl]carbonyl}amino)-2-phenylethyl]-1H-imidazol-4-yl}benzamide
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2014-07-07
Authors: Wei, A.
PDB entry 4ty7: Factor XIa in complex with the inhibitor (2S)-6-amino-N-{(1S)-1-[4-(3-amino-2H-indazol-6-yl)-5-chloro-1H-imidazol-2-yl]-2-phenylethyl}-2-ethylhexanamide
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.09 Å
Deposited: 2014-07-08
Authors: Wei, A.
PDB entry 4ty8: An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Hepatitis C virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.78 Å
Deposited: 2014-07-08
Authors: Shui, W., Yang, C., Lin, J., Chen, X., Qin, S., Chen, S.
PDB entry 4ty9: An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline
Classification: TRANAFERASE/TRANSFERASE INHIBITOR
Source organism: Hepatitis C virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.78 Å
Deposited: 2014-07-08
Authors: Shui, W., Yang, C., Lin, J., Chen, X., Qin, S., Chen, S.
PDB entry 4tya: An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Hepatitis C virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.94 Å
Deposited: 2014-07-08
Authors: Shui, W., Yang, C., Lin, J., Chen, X., Qin, S., Chen, S.
PDB entry 4tyb: An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Hepatitis C virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.93 Å
Deposited: 2014-07-08
Authors: Shui, W., Yang, C., Lin, J., Chen, X., Qin, S., Chen, S.
PDB entry 4tyd: Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease
Classification: HYDROLASE
Source organism: Hepatitis C virus (isolate 1)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.84 Å
Deposited: 2014-07-08
Authors: Parsy, C.
PDB entry 4tye: Structural analysis of the human Fibroblast Growth Factor Receptor 4 Kinase
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2014-07-08
Authors: Lesca, E., Lammens, A., Huber, R., Augustin, M.
PDB entry 4tyf: Structure of a Metallo-beta-lactamase
Classification: HYDROLASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.1 Å
Deposited: 2014-07-08
Authors: Ferguson, J.A., Makena, A., Brem, J., McDonough, M.A., Schofield, C.J.
PDB entry 4tyg: Structural analysis of the human Fibroblast Growth Factor Receptor 4 Kinase
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2014-07-08
Authors: Lesca, E., Lammens, A., Huber, R., Augustin, M.
PDB entry 4tyh: Ternary complex of P38 and MK2 with a P38 inhibitor
Classification: Transferase/Transferase inhibitor
Source organism: Homo sapiens; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2014-07-08
Authors: Cumming, J.G., Debreczeni, J.E., Edfeldt, F., Evertsson, F., Harrison, M., Holdgate, G., James, M., Lamont, S., Oldham, K., Sullivan, J.E., Wells, S.
PDB entry 4tyi: Structural analysis of the human Fibroblast Growth Factor Receptor 4
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.4 Å
Deposited: 2014-07-08
Authors: Lesca, E., Lammens, A., Huber, R., Augustin, M.
PDB entry 4tyj: Structural analysis of the human Fibroblast Growth Factor Receptor 4 Kinase
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.45 Å
Deposited: 2014-07-08
Authors: Lesca, E., Lammens, A., Huber, R., Augustin, M.
PDB entry 4tyl: Fragment-Based Screening of the Bromodomain of ATAD2
Classification: Hydrolase/Hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2014-07-08
Authors: Harner, M.J., Chauder, B.A., Phan, J., Fesik, S.W.
PDB entry 4tym: Crystal structure of purine nucleoside phosphorylase from Streptococcus agalactiae 2603V/R, NYSGRC Target 030935
Classification: TRANSFERASE
Source organism: Streptococcus agalactiae LMG 15084
Experimental method: X-RAY DIFFRACTION
Resolution: 2.399 Å
Deposited: 2014-07-08
Authors: Malashkevich, V.N., Bhosle, R., Toro, R., Hillerich, B., Gizzi, A., Garforth, S., Kar, A., Chan, M.K., Lafluer, J., Patel, H., Matikainen, B., Chamala, S., Lim, S., Celikgil, A., Villegas, G., Evans, B., Love, J., Fiser, A., Seidel, R., Bonanno, J.B., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4tyn: DEAD-box helicase Mss116 bound to ssDNA and ADP-BeF
Classification: HYDROLASE/DNA
Source organism: Saccharomyces cerevisiae; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.959 Å
Deposited: 2014-07-08
Authors: Mallam, A.L., Sidote, D.J., Lambowitz, A.M.
PDB entry 4tyo: PPIase in complex with a non-phosphate small molecule inhibitor.
Classification: ISOMERASE/ISOMERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2014-07-08
Authors: Greasley, S.E., Ferre, R.A.
PDB entry 4typ: Crystal structure of an adenylate kinase mutant--AKm1
Classification: TRANSFERASE
Source organism: Bacillus subtilis 168
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2014-07-09
Authors: Moon, S., Bae, E.
PDB entry 4tyq: Crystal structure of an adenylate kinase mutant--AKm2
Classification: TRANSFERASE
Source organism: Bacillus subtilis 168
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2014-07-09
Authors: Moon, S., Bae, E.
PDB entry 4tys: Crystal structure of Canavalia maritima lectin (ConM) complexed with a dinucleotide
Classification: Carbohydrate binding protein
Source organism: Canavalia lineata
Experimental method: X-RAY DIFFRACTION
Resolution: 3.25 Å
Deposited: 2014-07-09
Authors: Vieira, D.B.H.A., Delatorre, P., Silva-Filho, J.C., Nobrega, R.B., Cavada, B.S., Rocha, B.A.M., Lima, E.M., Teixeira, C.S.
PDB entry 4tyt: Crystal Structure of BcII metallo-beta-lactamase in complex with ML302F
Classification: HYDROLASE
Source organism: Bacillus cereus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.799 Å
Deposited: 2014-07-09
Authors: Brem, J., van Berkel, S.S., McDonough, M.A., Schofield, C.J.
PDB entry 4tyu: Homodimeric Single Domain Antibody (sdAb) against Staphylococcal enterotoxin B (SEB)
Classification: IMMUNE SYSTEM
Source organism: Lama glama
Experimental method: X-RAY DIFFRACTION
Resolution: 2.13 Å
Deposited: 2014-07-09
Authors: Legler, P.M.
PDB entry 4tyv: Ensemble refinement of the E502A variant of sacteLam55A from Streptomyces sp. SirexAA-E in complex with glucose
Classification: HYDROLASE
Source organism: Streptomyces sp. SirexAA-E
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2014-07-09
Authors: Bianchetti, C.M., Takasuka, T.E., Yik, E.J., Bergeman, L.F., Fox, B.G.
PDB entry 4tyw: DEAD-box helicase Mss116 bound to ssRNA and ADP-BeF
Classification: RNA BINDING PROTEIN/RNA
Source organism: Saccharomyces cerevisiae; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.197 Å
Deposited: 2014-07-09
Authors: Mallam, A.L., Sidote, D.J., Lambowitz, A.M.
PDB entry 4tyx: Structure of aquoferric sperm whale myoglobin L29H/F33Y/F43H/S92A mutant
Classification: OXYGEN TRANSPORT,OXIDOREDUCTASE
Source organism: Physeter catodon
Experimental method: X-RAY DIFFRACTION
Resolution: 1.64 Å
Deposited: 2014-07-09
Authors: Bhagi-Damodaran, A., Petrik, I.D., Robinson, H., Lu, Y.
PDB entry 4tyy: DEAD-box helicase Mss116 bound to ssRNA and CDP-BeF
Classification: RNA BINDING PROTEIN/RNA
Source organism: Saccharomyces cerevisiae; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.74 Å
Deposited: 2014-07-09
Authors: Mallam, A.L., Sidote, D.J., Lambowitz, A.M.
PDB entry 4tyz: Crystal structure of the C-terminal domain of an unknown protein from Leishmania infantum
Classification: UNKNOWN FUNCTION
Source organism: Leishmania infantum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2014-07-09
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 4tz0: DEAD-box helicase Mss116 bound to ssRNA and GDP-BeF
Classification: RNA BINDING PROTEIN/RNA
Source organism: Saccharomyces cerevisiae; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2014-07-09
Authors: Mallam, A.L., Sidote, D.J., Lambowitz, A.M.
PDB entry 4tz1: Ensemble refinement of the E502A variant of sacteLam55A from Streptomyces sp. SirexAA-E in complex with laminaritriose
Classification: HYDROLASE
Source organism: Streptomyces sp. SirexAA-E
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2014-07-09
Authors: Bianchetti, C.M., Takasuka, T.E., Yik, E.J., Bergeman, L.F., Fox, B.G.
PDB entry 4tz2: Fragment-Based Screening of the Bromodomain of ATAD2
Classification: Hydrolase/Hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2014-07-09
Authors: Harner, M.J., Chauder, B.A., Phan, J., Fesik, S.W.
PDB entry 4tz3: Ensemble refinement of the E502A variant of sacteLam55A from Streptomyces sp. SirexAA-E in complex with laminaritetraose
Classification: HYDROLASE
Source organism: Streptomyces sp. SirexAA-E
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2014-07-09
Authors: Bianchetti, C.M., Takasuka, T.E., Yik, E.J., Bergeman, L.F., Fox, B.G.
PDB entry 4tz4: Crystal Structure of Human Cereblon in Complex with DDB1 and Lenalidomide
Classification: DNA Binding Protein/Ligase
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.01 Å
Deposited: 2014-07-09
Authors: Chamberlain, P.P., Pagarigan, B., Delker, S., Leon, B., Riley, M.
PDB entry 4tz5: Ensemble refinement of the E502A variant of sacteLam55A from Streptomyces sp. SirexAA-E in complex with laminarihexaose
Classification: HYDROLASE
Source organism: Streptomyces sp. SirexAA-E
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2014-07-09
Authors: Bianchetti, C.M., Takasuka, T.E., Yik, E.J., Bergeman, L.F., Fox, B.G.
PDB entry 4tz6: DEAD-box helicase Mss116 bound to ssRNA and UDP-BeF
Classification: RNA BINDING PROTEIN/RNA
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.209 Å
Deposited: 2014-07-09
Authors: Mallam, A.L., Sidote, D.J., Lambowitz, A.M.
PDB entry 4tz7: Crystal structure of type I phosphatidylinositol 4-phosphate 5-kinase alpha from Zebrafish
Classification: TRANSFERASE
Source organism: Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 3.31 Å
Deposited: 2014-07-09
Authors: Hu, J., Qin, Y., Wang, J., Li, L., Wu, D., Ha, Y.
PDB entry 4tz8: Structure of human ATAD2 bromodomain bound to fragment inhibitor
Classification: Hydrolase/Hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2014-07-09
Authors: Harner, M.J., Chauder, B.A., Phan, J., Fesik, S.W.
PDB entry 4tz9: Structure of Metallo-beta-lactamase
Classification: HYDROLASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1269 Å
Deposited: 2014-07-09
Authors: Ferguson, J.A., Brem, J., Makena, A., McDonough, A.M., Schofield, C.J.
PDB entry 4tza: TGP, an extremely thermostable green fluorescent protein created by structure-guided surface engineering
Classification: FLUORESCENT PROTEIN
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2014-07-09
Authors: Close, D.W., Bradbury, A.R.M.
PDB entry 4tzb: Structure of NDM-Metallo-beta-lactamase
Classification: HYDROLASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.029 Å
Deposited: 2014-07-09
Authors: Ferguson, J.A., Makena, A., Brem, J., McDonough, M.A., Schofield, C.J.
PDB entry 4tzc: Crystal Structure of Murine Cereblon in Complex with Thalidomide
Classification: LIGASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.88 Å
Deposited: 2014-07-10
Authors: Chamberlain, P.P., Pagarigan, B., Delker, S., Leon, B.
PDB entry 4tzd: Crystal structure of Canavalia maritima lectin (ConM) complexed with interleukin - 1 beta primer
Classification: Carbohydrate binding protein/DNA
Source organism: Canavalia lineata; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2 Å
Deposited: 2014-07-10
Authors: Vieira, D.B.H.A., Delatorre, P., Rocha, B.A.M., Teixeira, C.S., Silva-Filho, J.C., Lima, E.M., Nobrega, R.B., Cavada, B.S.
PDB entry 4tze: Structure of metallo-beta-lactamase
Classification: HYDROLASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.574 Å
Deposited: 2014-07-10
Authors: Ferguson, J.A., Makena, A., Brem, J., McDonough, M.A., Schofield, C.J.
PDB entry 4tzf: Structure of metallo-beta lactamase
Classification: HYDROLASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.22 Å
Deposited: 2014-07-10
Authors: Ferguson, J.A., Makena, A., Brem, J., McDonough, M.A., Schofield, C.J.
PDB entry 4tzg: Crystal structure of eCGP123, an extremely thermostable green fluorescent protein
Classification: FLUORESCENT PROTEIN
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2014-07-10
Authors: Close, D.W., Don Paul, C., Traore, D.A.K., Wilce, M.C.J., Prescott, M., Bradbury, A.R.M.
PDB entry 4tzh: Structure of Leptospira interrogans LRR protein LIC12234
Classification: UNKNOWN FUNCTION
Source organism: Leptospira interrogans
Experimental method: X-RAY DIFFRACTION
Resolution: 1.39 Å
Deposited: 2014-07-10
Authors: Shepard, W., Saul, F.A., Haouz, A., Picardeau, M.
PDB entry 4tzi: Structure of unliganded Lyn SH2 domain
Classification: TRANSFERASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2014-07-10
Authors: Wybenga-Groot, L.E.
PDB entry 4tzj: Structure of C. elegans HIM-3 bound to HTP-3 closure motif-4
Classification: PEPTIDE BINDING PROTEIN
Source organism: Caenorhabditis elegans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.851 Å
Deposited: 2014-07-10
Authors: Rosenberg, S.C., Corbett, K.D.
PDB entry 4tzk: Crystal structure of Mycobacterium tuberculosis enoyl reductase (INHA) complexed WITH 1-CYCLOHEXYL-N-(3,5-DICHLOROPHENYL)-5-OXOPYRROLIDINE-3-CARBOXAMIDE
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.62 Å
Deposited: 2014-07-10
Authors: He, X., Alian, A., Stroud, R.M., Ortiz de Montellano, P.R.
PDB entry 4tzl: Structure of C. elegans HTP-2 bound to HIM-3 closure motif, P21 form
Classification: PEPTIDE BINDING PROTEIN
Source organism: Caenorhabditis elegans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.537 Å
Deposited: 2014-07-10
Authors: Rosenberg, S.C., Corbett, K.D.
PDB entry 4tzm: C. elegans HTP-2 bound to HTP-3 closure motif 1
Classification: PEPTIDE BINDING PROTEIN
Source organism: Caenorhabditis elegans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2014-07-10
Authors: Rosenberg, S.C., Corbett, K.D.
PDB entry 4tzn: Structure of HTP-2 bound to HTP-3 motif-6
Classification: PEPTIDE BINDING PROTEIN
Source organism: Caenorhabditis elegans
Experimental method: X-RAY DIFFRACTION
Resolution: 3.115 Å
Deposited: 2014-07-10
Authors: Rosenberg, S.C., Corbett, K.D.
PDB entry 4tzo: Structure of C. elegans HTP-1 bound to HIM-3 closure motif
Classification: PEPTIDE BINDING PROTEIN
Source organism: Caenorhabditis elegans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2014-07-10
Authors: Rosenberg, S.C., Corbett, K.D.
PDB entry 4tzp: As Grown, Untreated Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its cognate tRNAGly, and B. subtilis YbxF protein
Classification: Ribosomal Protein/RNA
Source organism: Bacillus subtilis; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 8.503 Å
Deposited: 2014-07-10
Authors: Zhang, J., Ferre-D'Amare, A.R.
PDB entry 4tzq: Structure of C. elegans HTP-1 bound to HTP-3 motif-1
Classification: PEPTIDE BINDING PROTEIN
Source organism: Caenorhabditis elegans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2014-07-10
Authors: Rosenberg, S.C., Corbett, K.D.
PDB entry 4tzr: Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1561
Classification: TRANSFERASE
Source organism: Toxoplasma gondii
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2014-07-10
Authors: Merritt, E.A.
PDB entry 4tzs: Structure of C. elegans HTP-2 bound to HIM-3 closure motif, P212121 form
Classification: PEPTIDE BINDING PROTEIN
Source organism: Caenorhabditis elegans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.55 Å
Deposited: 2014-07-10
Authors: Rosenberg, S.C., Corbett, K.D.
PDB entry 4tzt: CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ENOYL REDUCTASE (INHA) COMPLEXED WITH N-(3-CHLORO-2-METHYLPHENYL)-1-CYCLOHEXYL- 5-OXOPYRROLIDINE-3-CARBOXAMIDE
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.86 Å
Deposited: 2014-07-10
Authors: He, X., Alian, A., Stroud, R.M., Ortiz de Montellano, P.R.
PDB entry 4tzu: Crystal Structure of Murine Cereblon in Complex with Pomalidomide
Classification: LIGASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2014-07-10
Authors: Chamberlain, P.P., Pagarigan, B., Delker, S., Leon, B.
PDB entry 4tzv: Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its Cognate tRNAGly, and B. subtilis YbxF protein, treated by removing lithium sulfate post crystallization
Classification: RIBOSOMAL PROTEIN/RNA
Source organism: Bacillus subtilis; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 5.03 Å
Deposited: 2014-07-11
Authors: Zhang, J., Ferre-D'Amare, A.R.
PDB entry 4tzw: Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its Cognate tRNAGly, and B. subtilis YbxF protein, treated by removing lithium sulfate and replacing Mg2+ with Sr2+ post crystallization
Classification: RIBOSOMAL PROTEIN/RNA
Source organism: Bacillus subtilis; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 4.671 Å
Deposited: 2014-07-11
Authors: Zhang, J., Ferre-D'Amare, A.R.
PDB entry 4tzx: Vibrio Vulnificus Adenine Riboswitch variant, grown in Mg2+
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.01 Å
Deposited: 2014-07-11
Authors: Zhang, J., Ferre-D'Amare, A.R.
PDB entry 4tzy: Vibrio vulnificus Adenine Riboswitch Variant, grown in both Sr2+ and Mg2+
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.57 Å
Deposited: 2014-07-11
Authors: Zhang, J., Ferre-D'Amare, A.R.
PDB entry 4tzz: Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its Cognate tRNAGly, and B. subtilis YbxF protein, treated by removing lithium sulfate and increasing PEG3350 concentration from 20% to 45% post crystallization
Classification: RIBOSOMAL PROTEIN/RNA
Source organism: Bacillus subtilis; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.64 Å
Deposited: 2014-07-11
Authors: Zhang, J., Ferre-D'Amare, A.R.
PDB entry 4u00: Crystal structure of TTHA1159 in complex with ADP
Classification: TRANSPORT PROTEIN
Source organism: Thermus thermophilus HB8
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2014-07-11
Authors: Karthiga Devi, S., Chichili, V.P.R., Velmurugan, D., Sivaraman, J.
PDB entry 4u01: HCV NS3/4A serine protease in complex with 6570
Classification: HYDROLASE
Source organism: Hepatitis C virus; Hepatitis C virus (isolate Con1)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2014-07-11
Authors: Parsy, C.C., Alexandre, F.-R., Brandt, G., Caillet, C., Chaves, D., Derock, M., Gloux, D., Griffon, Y., Lallos, L.B., Leroy, F., Liuzzi, M., Loi, A.-G., Mayes, B., Moulat, L., Moussa, A., Chiara, M., Roques, V., Rosinovsky, E., Seifer, M., Stewart, A., Wang, J., Standring, D., Surleraux, D.
PDB entry 4u02: Crystal structure of apo-TTHA1159
Classification: TRANSPORT PROTEIN
Source organism: Thermus thermophilus HB8
Experimental method: X-RAY DIFFRACTION
Resolution: 2.399 Å
Deposited: 2014-07-11
Authors: Karthiga Devi, S., Chichili, V.P.R., Velmurugan, D., Sivaraman, J.
PDB entry 4u03: Structure of the vibrio cholerae di-nucleotide cyclase (DncV) in complex with GTP and 5MTHFGLU2
Classification: TRANSFERASE
Source organism: Vibrio cholerae El Tor N16961
Experimental method: X-RAY DIFFRACTION
Resolution: 2.041 Å
Deposited: 2014-07-11
Authors: Zhu, D.Y., Xiang, Y.
PDB entry 4u04: Structure of a eukaryotic fic domain containing protein
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.48 Å
Deposited: 2014-07-11
Authors: Cole, A.R., Bunney, T.D., Katan, M.
PDB entry 4u05: Homodimeric Single Domain Antibody (sdAb) against Staphylococcal enterotoxin B (SEB) S74A Variant
Classification: IMMUNE SYSTEM
Source organism: Lama glama
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2014-07-11
Authors: Legler, P.M.
PDB entry 4u06: Structure of Leptospira interrogans LRR protein LIC10831
Classification: UNKNOWN FUNCTION
Source organism: Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2014-07-11
Authors: Shepard, W., Saul, F.A., Haouz, A., Picardeau, M.
PDB entry 4u07: ATP bound to eukaryotic FIC domain containing protein
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.64 Å
Deposited: 2014-07-11
Authors: Cole, A.R., Bunney, T.D., Katan, M.
PDB entry 4u08: Structure of Leptospira interrogans LRR protein LIC11098
Classification: UNKNOWN FUNCTION
Source organism: Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2014-07-11
Authors: Shepard, W., Saul, F.A., Haouz, A., Picardeau, M.
PDB entry 4u09: Structure of Leptospira interrogans LRR protein LIC12759
Classification: UNKNOWN FUNCTION
Source organism: Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2014-07-11
Authors: Shepard, W., Saul, F.A., Haouz, A., Picardeau, M.
PDB entry 4u0a: Hexameric HIV-1 CA in complex with CPSF6 peptide, P6 crystal form
Classification: VIRAL PROTEIN
Source organism: Human immunodeficiency virus type 1 group M subtype B; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2014-07-11
Authors: Price, A.J., Jacques, D.A., James, L.C.
PDB entry 4u0b: Hexamer HIV-1 CA in complex with CPSF6 peptide, P212121 crystal form
Classification: VIRAL PROTEIN
Source organism: Human immunodeficiency virus type 1 group M subtype B; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2014-07-11
Authors: Price, A.J., Jacques, D.A., James, L.C.
PDB entry 4u0c: Hexameric HIV-1 CA in complex with Nup153 peptide, P6 crystal form
Classification: VIRAL PROTEIN
Source organism: Human immunodeficiency virus type 1 group M subtype B; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.77 Å
Deposited: 2014-07-11
Authors: Price, A.J., Jacques, D.A., James, L.C.
PDB entry 4u0d: Hexameric HIV-1 CA in complex with Nup153 peptide, P212121 crystal form
Classification: VIRAL PROTEIN
Source organism: Human immunodeficiency virus type 1 group M subtype B; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2014-07-11
Authors: Price, A.J., Jacques, D.A., James, L.C.
PDB entry 4u0e: Hexameric HIV-1 CA in complex with PF3450074
Classification: VIRAL PROTEIN
Source organism: Human immunodeficiency virus type 1 group M subtype B
Experimental method: X-RAY DIFFRACTION
Resolution: 2.043 Å
Deposited: 2014-07-11
Authors: Price, A.J., Jacques, D.A., James, L.C.
PDB entry 4u0f: Hexameric HIV-1 CA in Complex with BI-2
Classification: VIRAL PROTEIN
Source organism: Human immunodeficiency virus type 1 group M subtype B
Experimental method: X-RAY DIFFRACTION
Resolution: 2.22 Å
Deposited: 2014-07-11
Authors: Price, A.J., Jacques, D.A., James, L.C.
PDB entry 4u0g: Crystal Structure of M. tuberculosis ClpP1P2 bound to ADEP and agonist
Classification: hydrolase/antibiotic
Source organism: Mycobacterium tuberculosis H37Rv; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1978 Å
Deposited: 2014-07-11
Authors: Schmitz, K.R., Carney, D.W., Sello, J.K., Sauer, R.T.
PDB entry 4u0h: Crystal Structure of M. tuberculosis ClpP1P1
Classification: HYDROLASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2479 Å
Deposited: 2014-07-11
Authors: Schmitz, K.R., Carney, D.W., Sello, J.K., Sauer, R.T.
PDB entry 4u0i: Crystal structure of KIT in complex with ponatinib
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2014-07-11
Authors: Zhou, T., Zhu, X., Dalgarno, D.C.
PDB entry 4u0j: Crystal structure of Mycobacterium tuberculosis enoyl reductase (INHA) complexed with 1-CYCLOHEXYL-5-OXO-N-PHENYLPYRROLIDINE-3-CARBOXAMIDE, refined with new ligand restraints
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.62 Å
Deposited: 2014-07-11
Authors: He, X., Alian, A., Stroud, R.M., Ortiz de Montellano, P.R.
PDB entry 4u0k: Crystal structure of Mycobacterium tuberculosis enoyl reductase complexed with N-(5-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2014-07-11
Authors: He, X., Alian, A., Stroud, R.M., Ortiz de Montellano, P.R.
PDB entry 4u0l: Structure of the Vibrio cholerae di-nucleotide cyclase (DncV) mutant D131A-D133A
Classification: TRANSFERASE
Source organism: Vibrio cholerae El Tor N16961
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2014-07-12
Authors: Xiang, Y., Zhu, D.Y.
PDB entry 4u0m: Structure of the Vibrio cholerae di-nucleotide cyclase (DncV) mutant D193N in complex with ATP, GTP and 5MTHFGLU2
Classification: TRANSFERASE
Source organism: Vibrio cholerae El Tor N16961
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2014-07-12
Authors: Zhu, D., Xiang, Y.
PDB entry 4u0n: Structure of the Vibrio cholerae di-nucleotide cyclase (DncV) deletion mutant D-loop
Classification: TRANSFERASE
Source organism: Vibrio cholerae El Tor N16961
Experimental method: X-RAY DIFFRACTION
Resolution: 2.102 Å
Deposited: 2014-07-12
Authors: Xiang, Y., Zhu, D.Y.
PDB entry 4u0o: Crystal structure of Thermosynechococcus elongatus Lipoyl Synthase 2 complexed with MTA and DTT
Classification: TRANSFERASE
Source organism: Thermosynechococcus elongatus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2014-07-13
Authors: Harmer, J.E., Hiscox, M.J., Dinis, P.C., Sandy, J., Roach, P.L.
PDB entry 4u0p: The Crystal Structure of Lipoyl Synthase in Complex with S-Adenosyl Homocysteine
Classification: TRANSFERASE
Source organism: Thermosynechococcus elongatus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.623 Å
Deposited: 2014-07-13
Authors: Harmer, J.E., Hiscox, M.J., Sandy, J., Dinis, P.C., Roach, P.L.