LiteFold/PDB huggingface dataset:
PDB entry 6c5n: Crystal structure of Staphylococcus aureus ketol-acid reductoisomerase with hydroxyoxamate inhibitor 1
Classification: OXIDOREDUCTASE
Source organism: Staphylococcus aureus (strain bovine RF122 / ET3-1)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.673 Å
Deposited: 2018-01-16
Authors: Kandale, A., Patel, K.M., Zheng, S., You, L., Guddat, L.W., Schenk, G., Schembri, M.A., McGeary, R.P.
PDB entry 6c5q: PPARg LBD bound to SR10171
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.404 Å
Deposited: 2018-01-16
Authors: Bruning, J.B., Frkic, R.L.
PDB entry 6c5r: Crystal structure of the soluble domain of the mitochondrial calcium uniporter
Classification: CYTOSOLIC PROTEIN
Source organism: Metarhizium acridum (strain CQMa 102)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.09608 Å
Deposited: 2018-01-16
Authors: Fan, C., Fan, M., Fastman, N., Zhang, J., Feng, L.
PDB entry 6c5t: PPARg LBD bound to SR11023
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.75 Å
Deposited: 2018-01-16
Authors: Bruning, J.B., Frkic, R.L., Griffin, P.R.
PDB entry 6c5u: Aminoglycoside Phosphotransferase (2'')-Ia in complex with GMPPNP, Magnesium, and Ribostamycin, Alternate form
Classification: TRANSFERASE/Antibiotic
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.41 Å
Deposited: 2018-01-16
Authors: Caldwell, S.J., Berghuis, A.M.
PDB entry 6c5v: An anti-gH/gL antibody that neutralizes dual-tropic infection defines a site of vulnerability on Epstein-Barr virus
Classification: VIRAL PROTEIN
Source organism: Homo sapiens; Human herpesvirus 4
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.8 Å
Deposited: 2018-01-16
Authors: Snijder, J., Ortego, M.S., Weidle, C., Stuart, A.B., Gray, M.A., McElrath, M.J., Pancera, M., Veesler, D., McGuire, A.T., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 6c5w: Crystal structure of the mitochondrial calcium uniporter
Classification: MEMBRANE PROTEIN
Source organism: Metarhizium acridum (strain CQMa 102); unknown
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1001 Å
Deposited: 2018-01-17
Authors: Fan, C., Fan, M., Fastman, N., Zhang, J., Feng, L.
PDB entry 6c5x: Crystal Structure of SOCS1 in complex with ElonginB and ElonginC
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens; Xenopus laevis; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.105 Å
Deposited: 2018-01-17
Authors: Kershaw, N.J., Laktyushin, A., Babon, J.J.
PDB entry 6c5y: Crystal structure of thaumatin from microcrystals
Classification: PLANT PROTEIN
Source organism: Thaumatococcus daniellii
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2018-01-17
Authors: Guo, G., Fuchs, M., Shi, W., Skinner, J., Berman, E., Ogata, C.M., Hendrickson, W.A., McSweeney, S., Liu, Q.
PDB entry 6c5z: Human UDP-Glucose Dehydrogenase A225L substitutuion with UDP-glucose and NADH bound
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.95 Å
Deposited: 2018-01-17
Authors: Gross, P.G., Sidlo, A.M., Walsh, R.M., Peeples, W.B., Wood, Z.A.
PDB entry 6c61: MHC-independent T-cell receptor B12A
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.43 Å
Deposited: 2018-01-17
Authors: Lu, J., Sun, P.
PDB entry 6c62: An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme.
Classification: HYDROLASE
Source organism: Pseudomonas sp. (strain ADP)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2018-01-17
Authors: Peat, T.S., Esquirol, L., Wilding, M., Liu, J.W., French, N.G., Hartley, C.J., Hideki, O., Easton, C.J., Newman, J., Scott, C.
PDB entry 6c63: Crystal Structure of the Mango-II Fluorescent Aptamer Bound to TO1-Biotin
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.90003 Å
Deposited: 2018-01-17
Authors: Trachman, R.J., Ferre-D'Amare, A.R.
PDB entry 6c64: Crystal Structure of the Mango-II Fluorescent Aptamer Bound to TO3-Biotin
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 3.00015 Å
Deposited: 2018-01-17
Authors: Trachman, R.J., Ferre-D'Amare, A.R.
PDB entry 6c65: Crystal Structure of the Mango-II-A22U Fluorescent Aptamer Bound to TO1-Biotin
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.80005 Å
Deposited: 2018-01-17
Authors: Trachman, R.J., Ferre-D'Amare, A.R.
PDB entry 6c66: CRISPR RNA-guided surveillance complex, pre-nicking
Classification: DNA BINDING PROTEIN/DNA/RNA
Source organism: Thermobifida fusca; Thermobifida fusca (strain YX); SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.66 Å
Deposited: 2018-01-17
Authors: Xiao, Y., Luo, M., Liao, M., Ke, A.
PDB entry 6c67: Mycobacterium tuberculosis adenosine kinase bound to iodotubercidin
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.11 Å
Deposited: 2018-01-17
Authors: Crespo, R.A., TB Structural Genomics Consortium (TBSGC)
PDB entry 6c68: MHC-independent t cell receptor A11
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.59 Å
Deposited: 2018-01-18
Authors: Lu, J., Van Laethem, F., Saba, I., Chu, J., Bhattacharya, A., Love, N.C., Tikhonova, A., Radaev, S., Sun, X., Ko, A., Arnon, T., Shifrut, E., Friedman, N., Weng, N., Singer, A., Sun, P.D.
PDB entry 6c69: Structure of glycolipid aGSA[12,6P] in complex with mouse CD1d
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.937 Å
Deposited: 2018-01-18
Authors: Zajonc, D.M., Wang, J.
PDB entry 6c6a: Structure of glycolipid aGSA[16,6P] in complex with mouse CD1d
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.45 Å
Deposited: 2018-01-18
Authors: Zajonc, D.M., Wang, J.
PDB entry 6c6b: Co-crystal structure of adenylyl-sulfate kinase from Cryptococcus neoformans bound to ADP
Classification: TRANSFERASE
Source organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2018-01-18
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 6c6c: Structure of glycolipid aGSA[20,6P] in complex with mouse CD1d
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.08 Å
Deposited: 2018-01-18
Authors: Zajonc, D.M., Wang, J.
PDB entry 6c6d: 20mer crystal structure of CC chemokine 5 (CCL5)
Classification: CYTOKINE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 5.5 Å
Deposited: 2018-01-18
Authors: Liang, W.G., Tang, W.J.
PDB entry 6c6e: Structure of glycolipid aGSA[26,6P] in complex with mouse CD1d
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.18 Å
Deposited: 2018-01-18
Authors: Zajonc, D.M., Wang, J.
PDB entry 6c6f: Structure of glycolipid aGSA[26,P5p] in complex with mouse CD1d
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.67 Å
Deposited: 2018-01-18
Authors: Zajonc, D.M., Wang, J.
PDB entry 6c6g: An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme. Inhibitor bound complex.
Classification: HYDROLASE
Source organism: Pseudomonas sp. ADP
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2018-01-18
Authors: Peat, T.S., Esquirol, L., Wilding, M., Liu, J.W., French, N.G., Hartley, C.J., Hideki, O., Easton, C.J., Newman, J., Scott, C.
PDB entry 6c6h: Structure of glycolipid aGSA[8,P5m] in complex with mouse CD1d
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2018-01-18
Authors: Zajonc, D.M., Wang, J.
PDB entry 6c6i: Crystal structure of a chimeric NDM-1 metallo-beta-lactamase harboring the IMP-1 L3 loop
Classification: HYDROLASE
Source organism: Klebsiella pneumoniae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2018-01-18
Authors: Otero, L., Giannini, E., Klinke, S., Palacios, A., Mojica, M., Bonomo, R., Llarrull, L., Vila, A.
PDB entry 6c6j: Structure of glycolipid aGSA[8,P5p] in complex with mouse CD1d
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.79 Å
Deposited: 2018-01-18
Authors: Zajonc, D.M., Wang, J.
PDB entry 6c6k: Structural basis for preferential recognition of cap 0 RNA by a human IFIT1-IFIT3 protein complex
Classification: RNA BINDING PROTEIN/RNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.54 Å
Deposited: 2018-01-18
Authors: Amarasinghe, G.K., Leung, D.W., Johnson, B., Xu, W.
PDB entry 6c6l: Yeast Vacuolar ATPase Vo in lipid nanodisc
Classification: MEMBRANE PROTEIN
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.5 Å
Deposited: 2018-01-19
Authors: Roh, S., Stam, N.J., Hryc, C., Couoh-Cardel, S., Pintilie, G., Chiu, W., Wilkens, S.
PDB entry 6c6m: IgCam3 of human MLCK1
Classification: CELL ADHESION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2018-01-19
Authors: Zuccola, H.J., Turner, J.
PDB entry 6c6n: Human squalene epoxidase (SQLE, squalene monooxygenase) structure with FAD and Cmpd-4"
Classification: FLAVOPROTEIN/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2018-01-19
Authors: Padyana, A.K., Jin, L.
PDB entry 6c6o: Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 2-Br-4-OH-phenyldiketoacid
Classification: TRANSFERASE/TRANSFERASE inhibitor
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2018-01-19
Authors: Krieger, I.V., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
PDB entry 6c6p: Human squalene epoxidase (SQLE, squalene monooxygenase) structure with FAD and NB-598
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2018-01-19
Authors: Padyana, A.K., Jin, L.
PDB entry 6c6q: Crystal Structure of the Murine Norovirus VP1 P Domain in complex with the CD300lf Receptor
Classification: VIRAL PROTEIN/LIPID BINDING PROTEIN
Source organism: Murine norovirus 1; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2018-01-19
Authors: Nelson, C.A., Fremont, D.H.
PDB entry 6c6r: Human Squalene Epoxidase (SQLE, Squalene Monooxygenase) structure with FAD
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2018-01-19
Authors: Padyana, A.K., Jin, L.
PDB entry 6c6s: CryoEM structure of E.coli RNA polymerase elongation complex bound with RfaH
Classification: transcription/dna/rna
Source organism: Escherichia coli; Escherichia coli (strain K12); SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.7 Å
Deposited: 2018-01-19
Authors: Kang, J.Y., Artsimovitch, I., Landick, R., Darst, S.A.
PDB entry 6c6t: CryoEM structure of E.coli RNA polymerase elongation complex bound with RfaH
Classification: transcription/dna/rna
Source organism: Escherichia coli (strain K12); SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.5 Å
Deposited: 2018-01-19
Authors: Kang, J.Y., Artsimovitch, I., Landick, R., Darst, S.A.
PDB entry 6c6u: CryoEM structure of E.coli RNA polymerase elongation complex bound with NusG
Classification: transcription/dna/rna
Source organism: Escherichia coli (strain K12); SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.7 Å
Deposited: 2018-01-19
Authors: Kang, J.Y., Artsimovitch, I., Landick, R., Darst, S.A.
PDB entry 6c6w: Structure of a Complex Between Thaumatin and Thioflavin T
Classification: PROTEIN BINDING
Source organism: Thaumatococcus daniellii
Experimental method: X-RAY DIFFRACTION
Resolution: 2.23 Å
Deposited: 2018-01-19
Authors: McPherson, A.
PDB entry 6c6x: Crystal structure of Middle-East Respiratory Syndrome (MERS) coronavirus neutralizing antibody JC57-14 isolated from a vaccinated rhesus macaque.
Classification: IMMUNE SYSTEM
Source organism: Macaca mulatta
Experimental method: X-RAY DIFFRACTION
Resolution: 1.99 Å
Deposited: 2018-01-19
Authors: Joyce, M.G., Mascola, J.R., Graham, B.S., Kwong, P.D.
PDB entry 6c6y: Crystal structure of Middle-East Respiratory Syndrome (MERS) coronavirus neutralizing antibody JC57-14 isolated from a vaccinated rhesus macaque in complex with MERS Receptor Binding Domain
Classification: IMMUNE SYSTEM
Source organism: Betacoronavirus England 1; Macaca mulatta
Experimental method: X-RAY DIFFRACTION
Resolution: 3.32 Å
Deposited: 2018-01-19
Authors: Joyce, M.G., Mascola, J.R., Graham, B.S., Kwong, P.D.
PDB entry 6c6z: Crystal structure of potent neutralizing antibody CDC2-C2 in complex with MERS-CoV S1 RBD
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Middle East respiratory syndrome-related coronavirus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2018-01-19
Authors: Wang, N., McLellan, J.S.
PDB entry 6c70: Cryo-EM structure of Orco
Classification: MEMBRANE PROTEIN
Source organism: Apocrypta bakeri
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.5 Å
Deposited: 2018-01-19
Authors: Butterwick, J.A., Kim, K.H., Walz, T., Ruta, V.
PDB entry 6c71: Nicotine Oxidoreductase in Complex with S-nicotine
Classification: FLAVOPROTEIN
Source organism: Pseudomonas putida (strain S16)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.649 Å
Deposited: 2018-01-19
Authors: Tararina, M.A., Allen, K.N.
PDB entry 6c72: Crystal structure of a tailspike protein gp49 from Acinetobacter baumannii bacteriophage Fri1, a capsular polysaccharide depolymerase
Classification: HYDROLASE
Source organism: Acinetobacter phage Fri1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.396 Å
Deposited: 2018-01-19
Authors: Buth, S.A., Garcon, A., Popova, A.V., Shneider, M.M., Leiman, P.G.
PDB entry 6c73: Tryptophan synthase Q114A mutant (internal aldimine state) in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) with cesium ion bound in the metal coordination site
Classification: LYASE
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2018-01-19
Authors: Hilario, E., Dunn, M.F., Mueller, L.J., Fan, L.
PDB entry 6c74: Crystal Structure of Murine CD300lf in complex with phosphocholine
Classification: LIPID BINDING PROTEIN
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.358 Å
Deposited: 2018-01-19
Authors: Nelson, C.A., Fremont, D.H.
PDB entry 6c75: Structure of Iron containing alcohol dehydrogenase from Thermococcus thioreducens in a monoclinic crystal form
Classification: OXIDOREDUCTASE
Source organism: Thermococcus thioreducens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2018-01-19
Authors: Larson, S.B., McPherson, A.
PDB entry 6c76: Structure of Iron containing alcohol dehydrogenase from Thermococcus thioreducens in an orthorhombic crystal form
Classification: OXIDOREDUCTASE
Source organism: Thermococcus thioreducens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2018-01-20
Authors: Larson, S.B., McPherson, A.
PDB entry 6c78: Substrate Binding Induces Conformational Changes In A Class A Beta Lactamase That Primes It For Catalysis
Classification: HYDROLASE
Source organism: Escherichia coli
Experimental method: NEUTRON DIFFRACTION
Resolution: 1.75 Å
Deposited: 2018-01-22
Authors: Langan, P.S., Vandavasi, V.G., Cooper, S.J., Weiss, K.L., Ginell, S.L., Parks, J.M., Coates, L.
PDB entry 6c79: Conformational Changes in a Class A Beta lactamase that Prime it for Catalysis
Classification: HYDROLASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.1 Å
Deposited: 2018-01-22
Authors: Coates, L., Langan, P.S., Vandavasi, V.G., Cooper, S.J., Weiss, K.L., Ginell, S.L., Parks, J.M.
PDB entry 6c7a: Conformational Changes in a Class A Beta lactamase that Prime it for Catalysis
Classification: HYDROLASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.05 Å
Deposited: 2018-01-22
Authors: Coates, L., Langan, P.S., Vandavasi, V.G., Cooper, S.J., Weiss, K.L., Ginell, S.L., Parks, J.M.
PDB entry 6c7b: Crystal structure of Mycobacterium tuberculosis malate synthase in complex with Methoxynaphthyldiketoacid
Classification: TRANSFERASE/TRANSFERASE inhibitor
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.133 Å
Deposited: 2018-01-22
Authors: Krieger, I.V., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
PDB entry 6c7c: Crystal structure of Enoyl-CoA hydratase, EchA3, from Mycobacterium ulcerans Agy99
Classification: LYASE
Source organism: Mycobacterium ulcerans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2018-01-22
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 6c7d: Crystal structure of human phosphodiesterase 2A with N-(1-adamantyl)-1-(2-chlorophenyl)-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.79 Å
Deposited: 2018-01-22
Authors: Xu, R., Aertgeerts, K.
PDB entry 6c7e: Crystal structure of human phosphodiesterase 2A with 1-(2-chlorophenyl)-N,4-dimethyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.43 Å
Deposited: 2018-01-22
Authors: Xu, R., Aertgeerts, K.
PDB entry 6c7f: Crystal structure of human phosphodiesterase 2A with 1-(2-chloro-5-isobutoxy-phenyl)-N,4-dimethyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.82 Å
Deposited: 2018-01-22
Authors: Xu, R., Aertgeerts, K.
PDB entry 6c7g: Crystal structure of human phosphodiesterase 2A with N-(1-adamantyl)-1-(2-chloro-5-isobutoxy-phenyl)-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.68 Å
Deposited: 2018-01-22
Authors: Xu, R., Aertgeerts, K.
PDB entry 6c7h: Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 18 Design Trp50Ala mutant
Classification: LYASE
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 2.43 Å
Deposited: 2018-01-22
Authors: Jackson, C.J., Hong, N.-S., Carr, P.D.
PDB entry 6c7i: Crystal structure of human phosphodiesterase 2A with 1-(2-chloro-5-methoxy-phenyl)-N-isobutyl-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.713 Å
Deposited: 2018-01-22
Authors: Xu, R., Aertgeerts, K.
PDB entry 6c7j: Crystal structure of human phosphodiesterase 2A with 1-(5-tert-butoxy-2-chloro-phenyl)-N-isobutyl-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2018-01-22
Authors: Xu, R., Aertgeerts, K.
PDB entry 6c7k: Crystal structure of an ACO/RPE65 chimera
Classification: OXIDOREDUCTASE
Source organism: Synechocystis sp. (strain PCC 6803 / Kazusa)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2018-01-22
Authors: Kiser, P.D., Shi, W.
PDB entry 6c7l: Structure of Iron containing alcohol dehydrogenase from Thermococcus thioreducens in a tetragonal crystal form
Classification: OXIDOREDUCTASE
Source organism: Thermococcus thioreducens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.91 Å
Deposited: 2018-01-22
Authors: Jones, J.A., Larson, S.B., McPherson, A.
PDB entry 6c7m: Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 19 round 5
Classification: LYASE
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2018-01-22
Authors: Jackson, C.J., Hong, N.-S., Carr, P.D.
PDB entry 6c7n: Monoclinic form of malic enzyme from sorghum at 2 angstroms resolution
Classification: OXIDOREDUCTASE
Source organism: Sorghum bicolor
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2018-01-23
Authors: Trajtenberg, F., Alvarez, C., Buschiazzo, A.
PDB entry 6c7o: Crystal structure of D477G ACO/RPE65 chimera, trigonal crystal form
Classification: OXIDOREDUCTASE
Source organism: Synechocystis sp. (strain PCC 6803 / Kazusa)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.15 Å
Deposited: 2018-01-23
Authors: Kiser, P.D., Shi, W.
PDB entry 6c7p: Crystal structure of D477G ACO/RPE65 chimera, monoclinic crystal form
Classification: OXIDOREDUCTASE
Source organism: Synechocystis sp. (strain PCC 6803 / Kazusa)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2018-01-23
Authors: Kiser, P.D., Shi, W.
PDB entry 6c7q: BRD4 BD2 in complex with compound CE277
Classification: transcription/transcription inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.51 Å
Deposited: 2018-01-23
Authors: Meagher, J.L., Stuckey, J.A.
PDB entry 6c7r: BRD4 BD1 in complex with compound CF53
Classification: transcription/transcription inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2018-01-23
Authors: Meagher, J.L., Stuckey, J.A.
PDB entry 6c7s: Structure of Rifampicin Monooxygenase with Product Bound
Classification: OXIDOREDUCTASE
Source organism: Nocardia farcinica (strain IFM 10152)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2018-01-23
Authors: Liu, L.-K., Tanner, J.J.
PDB entry 6c7t: Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 20 round 5
Classification: LYASE
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 1.83 Å
Deposited: 2018-01-23
Authors: Jackson, C.J., Hong, N.-S., Carr, P.D.
PDB entry 6c7v: Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 22 round 5
Classification: LYASE
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 1.64 Å
Deposited: 2018-01-23
Authors: Jackson, C.J., Hong, N.-S., Carr, P.D.
PDB entry 6c7w: Carbonic anhydrase 2 in complex with [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDRO-2-FURANYL]METHYL SULFAMATE inhibitor
Classification: LYASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.28 Å
Deposited: 2018-01-23
Authors: Peat, T.S., Mujumdar, P., Poulsen, S.A.
PDB entry 6c7x: Carbonic anhydrase 2 in complex with 2-chloro-5'-O-sulfamoyladenosine
Classification: LYASE/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2018-01-23
Authors: Peat, T.S., Mujumdar, P., Poulsen, S.A.
PDB entry 6c7y: Crystal structure of inhibitory protein SOCS1 in complex with JAK1 kinase domain
Classification: SIGNALING PROTEIN, TRANSFERASE/INHIBITOR
Source organism: Gallus gallus; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.499 Å
Deposited: 2018-01-23
Authors: Liau, N.P.D., Laktyushin, A., Lucet, I.S., Murphy, J.M., Yao, S., Callaghan, K., Nicola, N.A., Kershaw, N.J., Babon, J.J.
PDB entry 6c7z: Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with synthetic Ligand Julolidine
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.42 Å
Deposited: 2018-01-23
Authors: Nosrati, M., Geiger, J.H.
PDB entry 6c80: Crystal structure of a flax cytokinin oxidase
Classification: IMMUNE SYSTEM
Source organism: Linum usitatissimum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.78 Å
Deposited: 2018-01-23
Authors: Wan, L., Williams, S., Kobe, B.
PDB entry 6c83: Structure of Aurora A (122-403) bound to inhibitory Monobody Mb2 and AMPPCP
Classification: transferase/inhibitor
Source organism: Homo sapiens; synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 2.55 Å
Deposited: 2018-01-24
Authors: Hoemberger, M., Kutter, S., Zorba, A., Nguyen, V., Shohei, A., Shohei, K., Kern, D.
PDB entry 6c84: Crystal structure of PBP5 from Enterococcus faecium
Classification: MEMBRANE PROTEIN
Source organism: Enterococcus faecium
Experimental method: X-RAY DIFFRACTION
Resolution: 2.511 Å
Deposited: 2018-01-24
Authors: Shamoo, Y., Davlieva, M.
PDB entry 6c85: Crystal structure of aspartate semialdehyde dehydrogenase from Blastomyces dermatitidis with p-benzoquinone
Classification: OXIDOREDUCTASE
Source organism: Blastomyces gilchristii
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2018-01-24
Authors: Dahal, G.P., Viola, R.E.
PDB entry 6c86: Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-Lysylsulfamoyl Adenosine
Classification: LIGASE
Source organism: Cryptosporidium parvum (strain Iowa II)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2018-01-24
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 6c87: Crystal structure of rab gdp dissociation inhibitor alpha from Naegleria fowleri
Classification: PROTEIN TRANSPORT
Source organism: Naegleria fowleri
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2018-01-24
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 6c88: STRUCTURE OF THE AMYLOID FORMING PEPTIDE VAVHVF FROM TRANSTHYRETIN
Classification: PROTEIN FIBRIL
Experimental method: X-RAY DIFFRACTION
Resolution: 1.851 Å
Deposited: 2018-01-24
Authors: Saelices, L., Sawaya, M.R., Eisenberg, D.S.
PDB entry 6c89: NDM-1 Beta-Lactamase Exhibits Differential Active Site Sequence Requirements for the Hydrolysis of Penicillin versus Carbapenem Antibiotics
Classification: ANTIMICROBIAL PROTEIN
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75006 Å
Deposited: 2018-01-24
Authors: Palzkill, T., Sun, Z., Sankaran, B.
PDB entry 6c8b: Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 23 round 6
Classification: LYASE
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 1.61 Å
Deposited: 2018-01-24
Authors: Jackson, C.J., Hong, N.-S., Carr, P.D.
PDB entry 6c8c: Chimeric Pol kappa RIR Rev1 C-terminal domain in complex with JHRE06
Classification: REPLICATION
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2018-01-24
Authors: Najeeb, J., Zhou, P.
PDB entry 6c8d: RNA-dGMP complex with Mg ion
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.92 Å
Deposited: 2018-01-24
Authors: Zhang, W., Szostak, J.W.
PDB entry 6c8e: RNA-imidazolium-bridged intermediate complex, 4h soaking
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2018-01-24
Authors: Zhang, W., Szostak, J.W.
PDB entry 6c8f: Crystal structure of Transient Receptor Potential (TRP) channel TRPV4 in the presence of cesium
Classification: TRANSPORT PROTEIN
Source organism: Xenopus tropicalis
Experimental method: X-RAY DIFFRACTION
Resolution: 6.5 Å
Deposited: 2018-01-24
Authors: Deng, Z., Paknejad, N., Maksaev, G., Sala-Rabanal, M., Nichols, C.G., Hite, R.K., Yuan, P.
PDB entry 6c8g: Crystal structure of Transient Receptor Potential (TRP) channel TRPV4 in the presence of barium
Classification: TRANSPORT PROTEIN
Source organism: Xenopus tropicalis
Experimental method: X-RAY DIFFRACTION
Resolution: 6.31 Å
Deposited: 2018-01-24
Authors: Deng, Z., Paknejad, N., Maksaev, G., Sala-Rabanal, M., Nichols, C.G., Hite, R.K., Yuan, P.
PDB entry 6c8h: Crystal structure of Transient Receptor Potential (TRP) channel TRPV4 in the presence of gadolinium
Classification: TRANSPORT PROTEIN
Source organism: Xenopus tropicalis
Experimental method: X-RAY DIFFRACTION
Resolution: 6.5 Å
Deposited: 2018-01-24
Authors: Deng, Z., Paknejad, N., Maksaev, G., Sala-Rabanal, M., Nichols, C.G., Hite, R.K., Yuan, P.
PDB entry 6c8i: RNA-activated 2-AIpG monomer complex, 5 min soaking
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.77 Å
Deposited: 2018-01-24
Authors: Zhang, W., Szostak, J.W.
PDB entry 6c8j: RNA-activated 2-AIpG monomer complex, 15 min soaking
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2018-01-24
Authors: Zhang, W., Szostak, J.W.
PDB entry 6c8k: RNA-activated 2-AIpG monomer complex, 30 min soaking
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.259 Å
Deposited: 2018-01-24
Authors: Zhang, W., Szostak, J.W.
PDB entry 6c8l: RNA-activated 2-AIpG monomer complex, 1h soaking
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2018-01-25
Authors: Zhang, W., Szostak, J.W.
PDB entry 6c8m: RNA-activated 2-AIpG monomer, 1.5h soaking
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2018-01-25
Authors: Zhang, W., Szostak, J.W.
PDB entry 6c8n: RNA-activated 2-AIpG monomer complex, 2h soaking
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2018-01-25
Authors: Zhang, W., Szostak, J.W.
PDB entry 6c8o: RNA-activated 2-AIpG monomer, 3h soaking
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2018-01-25
Authors: Zhang, W., Szostak, J.W.
PDB entry 6c8p: Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 2-F-phenyldiketoacid
Classification: TRANSFERASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.635 Å
Deposited: 2018-01-25
Authors: Krieger, I.V., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
PDB entry 6c8q: Crystal structure of NAD synthetase (NadE) from Enterococcus faecalis in complex with NAD+
Classification: TRANSFERASE
Source organism: Enterococcus faecalis V583
Experimental method: X-RAY DIFFRACTION
Resolution: 2.583 Å
Deposited: 2018-01-25
Authors: Stogios, P.J., Skarina, T., McChesney, C., Grimshaw, S., Kwon, K., Anderson, W.F., Satchell, K.J.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 6c8r: Loganic acid O-methyltransferase complexed with SAH and loganic acid
Classification: TRANSFERASE
Source organism: Catharanthus roseus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.951 Å
Deposited: 2018-01-25
Authors: Petronikolou, N., Nair, S.K.
PDB entry 6c8s: Loganic acid methyltransferase with SAH
Classification: TRANSFERASE
Source organism: Catharanthus roseus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2018-01-25
Authors: Petronikolou, N., Nair, S.K.
PDB entry 6c8t: The structure of MppP soaked with the substrate L-Arg
Classification: OXIDOREDUCTASE
Source organism: Streptomyces wadayamensis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2018-01-25
Authors: Han, L., Silvaggi, N.R.
PDB entry 6c8u: Solution structure of Musashi2 RRM1
Classification: RNA BINDING PROTEIN
Source organism: Homo sapiens
Experimental method: SOLUTION NMR
Deposited: 2018-01-25
Authors: Xing, M., Lan, L., Douglas, J.T., Gao, P., Hanzlik, R.P., Xu, L.
PDB entry 6c8v: X-ray structure of PqqE from Methylobacterium extorquens
Classification: OXIDOREDUCTASE
Source organism: Methylobacterium extorquens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2 Å
Deposited: 2018-01-25
Authors: Gizzi, A.S., Grove, T.L., Bonanno, J.B., Almo, S.C.
PDB entry 6c8w: Crystal structure of Aspartate Semialdehyde Dehydrogenase with NADP from Blastomyces dermatitidis
Classification: OXIDOREDUCTASE
Source organism: Blastomyces gilchristii
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2018-01-25
Authors: Dahal, G.P., Viola, R.E.
PDB entry 6c8x: Wild-type HIV-1 protease in complex with a phenylboronic acid (P2') analog of darunavir
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.613 Å
Deposited: 2018-01-25
Authors: Windsor, I.W., Raines, R.T., Forest, K.T.
PDB entry 6c8y: D30N HIV-1 protease in complex with a phenylboronic acid (P2') analog of darunavir
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.942 Å
Deposited: 2018-01-25
Authors: Windsor, I.W., Raines, R.T., Forest, K.T.
PDB entry 6c8z: Last common ancestor of ADP-dependent phosphofructokinases from Methanosarcinales
Classification: TRANSFERASE
Source organism: Methanosarcinales
Experimental method: X-RAY DIFFRACTION
Resolution: 2.86 Å
Deposited: 2018-01-25
Authors: Castro-Fernandez, V., Gonzalez-Ordenes, F., Munoz, S., Fuentes, N., Leonardo, D., Fuentealba, M., Herrera-Morande, A., Maturana, P., Villalobos, P., Garratt, R.
PDB entry 6c90: Human Mtr4 helicase in complex with ZCCHC8-CTD
Classification: HYDROLASE/RNA binding protein
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2018-01-25
Authors: Puno, M.R., Lima, C.D.
PDB entry 6c91: Structure of GRP94 with a resorcinylic inhibitor.
Classification: chaperone/inhibitor
Source organism: Canis lupus familiaris
Experimental method: X-RAY DIFFRACTION
Resolution: 2.895 Å
Deposited: 2018-01-25
Authors: Que, N.L.S., Gewirth, D.T.
PDB entry 6c92: The structure of MppP soaked with the product 2-ketoarginine
Classification: OXIDOREDUCTASE
Source organism: Streptomyces wadayamensis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.834 Å
Deposited: 2018-01-25
Authors: Han, L., Silvaggi, N.R.
PDB entry 6c93: Effects of the E310A Mutation of Cytochrome P450 4B1 (CYP4B1) on n-Octane binding and Heme Ruffling
Classification: OXIDOREDUCTASE
Source organism: Oryctolagus cuniculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.674 Å
Deposited: 2018-01-25
Authors: Hsu, M.-H., Johnson, E.F.
PDB entry 6c94: Structure Of Cytochrome P450 4B1 (CYP4B1) Complexed with the Inhibitor HET0016
Classification: OXIDOREDUCTASE/INHIBITOR
Source organism: Oryctolagus cuniculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.72 Å
Deposited: 2018-01-25
Authors: Hsu, M.-H., Johnson, E.F.
PDB entry 6c95: The Human NatA (Naa10/Naa15) amino-terminal acetyltransferase complex bound to HYPK
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.15 Å
Deposited: 2018-01-25
Authors: Gottlieb, L., Marmorstein, R.
PDB entry 6c96: Cryo-EM structure of mouse TPC1 channel in the apo state
Classification: MEMBRANE PROTEIN
Source organism: Mus musculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.4 Å
Deposited: 2018-01-25
Authors: She, J., Guo, J., Chen, Q., Bai, X., Jiang, Y.
PDB entry 6c97: Crystal structure of FcRn at pH3
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2018-01-25
Authors: Fox III, D., Fairman, J.W.
PDB entry 6c98: Crystal structure of FcRn bound to UCB-84
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2018-01-25
Authors: Fox III, D., Lukacs, C.M.
PDB entry 6c99: Crystal structure of FcRn bound to UCB-303
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2018-01-25
Authors: Fox III, D., Abendroth, J., Porter, J., Deboves, H.
PDB entry 6c9a: Cryo-EM structure of mouse TPC1 channel in the PtdIns(3,5)P2-bound state
Classification: MEMBRANE PROTEIN
Source organism: Mus musculus
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.2 Å
Deposited: 2018-01-25
Authors: She, J., Guo, J., Chen, Q., Bai, X., Jiang, Y.
PDB entry 6c9b: The structure of MppP soaked with the products 4HKA and 2KA
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Streptomyces wadayamensis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.689 Å
Deposited: 2018-01-26
Authors: Han, L., Silvaggi, N.R.
PDB entry 6c9c: Crystal structure of LpxC from Pseudomonas aeruginosa in complex with racemic ligand PT803
Classification: hydrolase/hydrolase inhibitor
Source organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2018-01-26
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 6c9d: Crystal structure of KA1-autoinhibited MARK1 kinase
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.499 Å
Deposited: 2018-01-26
Authors: Emptage, R.P., Marmorstein, R.
PDB entry 6c9e: Crystal structure of Cysteine desulfurase from Legionella pneumophila Philadelphia 1
Classification: TRANSFERASE
Source organism: Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2018-01-26
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 6c9f: AMP-activated protein kinase bound to pharmacological activator R734
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.924 Å
Deposited: 2018-01-26
Authors: Yan, Y., Zhou, X.E., Novick, S., Shaw, S.J., Li, Y., Hitoshi, Y., Brunzelle, J.S., Griffin, P.R., Xu, H.E., Melcher, K.
PDB entry 6c9g: AMP-activated protein kinase bound to pharmacological activator R739
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2018-01-26
Authors: Yan, Y., Zhou, X.E., Novick, S., Shaw, S.J., Li, Y., Hitoshi, Y., Brunzelle, J.S., Griffin, P.R., Xu, H.E., Melcher, K.
PDB entry 6c9h: non-phosphorylated AMP-activated protein kinase bound to pharmacological activator R734
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.65 Å
Deposited: 2018-01-26
Authors: Yan, Y., Zhou, X.E., Novick, S., Shaw, S.J., Li, Y., Hitoshi, Y., Brunzelle, J.S., Griffin, P.R., Xu, H.E., Melcher, K.
PDB entry 6c9i: Single-Particle reconstruction of DARP14 - A designed protein scaffold displaying ~17kDa DARPin proteins - Scaffold
Classification: DE NOVO PROTEIN
Source organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.09 Å
Deposited: 2018-01-26
Authors: Gonen, S., Liu, Y., Yeates, T.O., Gonen, T.
PDB entry 6c9j: AMP-activated protein kinase bound to pharmacological activator R734
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.05 Å
Deposited: 2018-01-26
Authors: Yan, Y., Zhou, X.E., Novick, S., Shaw, S.J., Li, Y., Brunzelle, J.S., Hitoshi, Y., Griffin, P.R., Xu, H.E., Melcher, K.
PDB entry 6c9k: Single-Particle reconstruction of DARP14 - A designed protein scaffold displaying ~17kDa DARPin proteins
Classification: DE NOVO PROTEIN
Source organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); synthetic
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.49 Å
Deposited: 2018-01-26
Authors: Gonen, S., Liu, Y., Yeates, T.O., Gonen, T.
PDB entry 6c9l: MEF2B Apo Protein Structure
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2018-01-26
Authors: Lei, X., Chen, L.
PDB entry 6c9m: The Human NatA (Naa10/Naa15) amino-terminal acetyltransferase complex
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2018-01-26
Authors: Gottlieb, L., Marmorstein, R.
PDB entry 6c9n: Mycobacterium tuberculosis adenosine kinase bound to sangivamycin
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2018-01-28
Authors: Crespo, R.A., TB Structural Genomics Consortium (TBSGC)
PDB entry 6c9o: Selenomethionine mutant (V29Sem) of protein GB1 examined by X-ray diffraction
Classification: IMMUNE SYSTEM
Source organism: Streptococcus sp. group G
Experimental method: X-RAY DIFFRACTION
Resolution: 1.2 Å
Deposited: 2018-01-28
Authors: Chen, Q.
PDB entry 6c9p: Mycobacterium tuberculosis adenosine kinase bound to 6-methylmercaptopurine riboside
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2018-01-28
Authors: Crespo, R.A., TB Structural Genomics Consortium (TBSGC)
PDB entry 6c9q: Mycobacterium tuberculosis adenosine kinase bound to 5'-aminoadenosine
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2018-01-28
Authors: Crespo, R.A., TB Structural Genomics Consortium (TBSGC)
PDB entry 6c9r: Mycobacterium tuberculosis adenosine kinase bound to (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(thiophen-3-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2018-01-28
Authors: Crespo, R.A., TB Structural Genomics Consortium (TBSGC)
PDB entry 6c9s: Mycobacterium tuberculosis adenosine kinase bound to (2R,3R,4S,5R)-2-(6-([1,1'-biphenyl]-4-ylethynyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.23 Å
Deposited: 2018-01-28
Authors: Crespo, R.A., TB Structural Genomics Consortium (TBSGC)
PDB entry 6c9t: Transcriptional repressor, CouR
Classification: DNA BINDING PROTEIN
Source organism: Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.07 Å
Deposited: 2018-01-28
Authors: Cogan, D.P., Nair, S.K.
PDB entry 6c9u: Crystal structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase in complex with antibody fragment (Fab)
Classification: TRANSFERASE/immune system
Source organism: Homo sapiens; Saccharopolyspora erythraea
Experimental method: X-RAY DIFFRACTION
Resolution: 2.09 Å
Deposited: 2018-01-28
Authors: Deis, L.N., Li, X., Mathews, I.I., Khosla, C.
PDB entry 6c9v: Mycobacterium tuberculosis adenosine kinase bound to (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(4-phenylpiperazin-1-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2018-01-28
Authors: Crespo, R.A., TB Structural Genomics Consortium (TBSGC)
PDB entry 6c9w: Crystal Structure of a ligand bound LacY/Nanobody Complex
Classification: MEMBRANE PROTEIN
Source organism: Escherichia coli (strain K12); Lama glama
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2018-01-29
Authors: Kumar, H., Finer-Moore, J.S., Jiang, X., Smirnova, I., Kasho, V., Pardon, E., Steyaert, J., Kaback, H.R., Stroud, R.M.
PDB entry 6c9x: THE CRYSTAL STRUCTURE OF THE alpha-Glucosidase (GH 31) FROM RUMINOCOCCUS OBEUM ATCC 29174 in complex with voglibose
Classification: HYDROLASE
Source organism: Blautia obeum ATCC 29174
Experimental method: X-RAY DIFFRACTION
Resolution: 1.457 Å
Deposited: 2018-01-29
Authors: Tan, K., Tesar, C., Jedrzejczak, R., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 6c9y: Cryo-EM structure of E. coli RNAP sigma70 holoenzyme
Classification: TRANSCRIPTION
Source organism: Escherichia coli (strain K12)
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.25 Å
Deposited: 2018-01-29
Authors: Narayanan, A., Vago, F., Li, K., Qayyum, M.Z., Yenool, D., Jiang, W., Murakami, K.S.
PDB entry 6c9z: THE CRYSTAL STRUCTURE OF THE alpha-Glucosidase (GH 31) W169Y mutant FROM RUMINOCOCCUS OBEUM ATCC 29174 in complex with voglibose
Classification: HYDROLASE
Source organism: Blautia obeum ATCC 29174
Experimental method: X-RAY DIFFRACTION
Resolution: 2.101 Å
Deposited: 2018-01-29
Authors: Tan, K., Tesar, C., Jedrzejczak, R., Joachimiak, A., Midwest Center for Macromolecular Research (MCMR)
PDB entry 6ca0: Cryo-EM structure of E. coli RNAP sigma70 open complex
Classification: transcription/dna
Source organism: Escherichia coli (strain K12); SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 5.75 Å
Deposited: 2018-01-29
Authors: Narayanan, A., Vago, F., Li, K., Qayyum, M.Z., Yernool, D., Jiang, W., Murakami, K.S.
PDB entry 6ca1: THE CRYSTAL STRUCTURE OF THE W169Y MUTANT OF ALPHA-GLUCOSIDASE (GH 31) FROM RUMINOCOCCUS OBEUM ATCC 29174 in complex with miglitol
Classification: HYDROLASE
Source organism: Blautia obeum ATCC 29174
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2018-01-29
Authors: Tan, K., Tesar, C., Jedrzejczak, R., Joachimiak, A., Midwest Center for Macromolecular Research (MCMR)
PDB entry 6ca2: ENGINEERING THE HYDROPHOBIC POCKET OF CARBONIC ANHYDRASE II
Classification: LYASE(OXO-ACID)
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 1991-07-09
Authors: Alexander, R.S., Christianson, D.W.
PDB entry 6ca3: THE CRYSTAL STRUCTURE OF THE W169Y MUTANT OF ALPHA-GLUCOSIDASE (GH 31) FROM RUMINOCOCCUS OBEUM ATCC 29174 in complex with miglitol
Classification: HYDROLASE
Source organism: Blautia obeum ATCC 29174
Experimental method: X-RAY DIFFRACTION
Resolution: 1.743 Å
Deposited: 2018-01-29
Authors: Tan, K., Tesar, C., Jedrzejczak, R., Joachimiak, A., Midwest Center for Macromolecular Research (MCMR)
PDB entry 6ca4: Crystal structure of humanized D. rerio TDP2 by 14 mutations
Classification: HYDROLASE
Source organism: Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 1.623 Å
Deposited: 2018-01-29
Authors: Shi, K., Aihrara, H.
PDB entry 6ca6: Crystal structure of PCT64_35S, a broadly neutralizing anti-HIV antibody.
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.43 Å
Deposited: 2018-01-29
Authors: Murrell, S., Wilson, I.A.
PDB entry 6ca7: Crystal structure of PCT64_13C, a strain specific anti-HIV antibody
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.643 Å
Deposited: 2018-01-29
Authors: Murrell, S., Wilson, I.A.
PDB entry 6ca8: Crystal structure of Plasmodium falciparum topoisomerase II DNA-binding, cleavage and re-ligation domain
Classification: ISOMERASE
Source organism: Plasmodium falciparum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.331 Å
Deposited: 2018-01-29
Authors: Kumar, S., Kandavelu, P., Rathod, P.K.
PDB entry 6ca9: Crystal structure of Fab PCT64_LMCA (SAR), the least mutated common ancestor of the HIV-1 broadly neutralizing antibody lineage PCT64
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.702 Å
Deposited: 2018-01-29
Authors: Omorodion, O., Wilson, I.A.
PDB entry 6caa: CryoEM structure of human SLC4A4 sodium-coupled acid-base transporter NBCe1
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.9 Å
Deposited: 2018-01-29
Authors: Huynh, K.W., Jiang, J., Abuladze, N., Tsirulnikov, K., Kao, L., Shao, X., Newman, D., Azimov, R., Pushkin, A., Zhou, Z.H., Kurtz, I.
PDB entry 6cab: RNA-dGMP complex with Sr ion
Classification: RNA
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2018-01-29
Authors: Zhang, W., Szostak, J.W.