LiteFold/PDB huggingface dataset:
PDB entry 5edc: human FABP4 in complex with 6-Chloro-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acid at 1.29A
Classification: LIPID BINDING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.29 Å
Deposited: 2015-10-21
Authors: Rudolph, M.G., Ehler, A.
PDB entry 5edd: Crystal structure of Mycobacterium tuberculosis dUTPase R140K, H145W mutant
Classification: HYDROLASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.97 Å
Deposited: 2015-10-21
Authors: Nagy, G.N., Leveles, I., Lopata, A., Harmat, V., Toth, J., Vertessy, G.B.
PDB entry 5ede: CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH c13c(cc(s1)C(NCC2OCCC2)=O)c(nn3c4ccc(cc4)Cl)C, micromolar IC50=0.217
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2015-10-21
Authors: Joseph, C., Rudolph, M.G.
PDB entry 5edf: Crystal structure of the selenomethionine-substituted iron-regulated protein FrpD from Neisseria meningitidis
Classification: UNKNOWN FUNCTION
Source organism: Neisseria meningitidis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2015-10-21
Authors: Sviridova, E., Bumba, L., Rezacova, P., Sebo, P., Kuta Smatanova, I.
PDB entry 5edg: CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH c1(c(nc([nH]1)Cl)c2ccccc2)C4=NN(c3cccc(c3)OC(F)(F)F)C=CC4=O, micromolar IC50=0.029618
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2015-10-21
Authors: Joseph, C., Rudolph, M.G.
PDB entry 5edh: CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH n4c(C)n1c(nc(n1)CCc2nc(nn2C)N3CCCC3)c(c4)CC, micromolar IC50=0.0037753
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.03 Å
Deposited: 2015-10-21
Authors: Joseph, C., Rudolph, M.G.
PDB entry 5edi: CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH c2(c(n1nc(nc1c(c2)C)CCc3nc(nn3C)N4CCCC4)C)Cl, micromolar IC50=0.000279
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2015-10-21
Authors: Joseph, C., Rudolph, M.G.
PDB entry 5edj: Crystal structure of the Neisseria meningitidis iron-regulated outer membrane lipoprotein FrpD
Classification: UNKNOWN FUNCTION
Source organism: Neisseria meningitidis MC58
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2015-10-21
Authors: Sviridova, E., Bumba, L., Rezacova, P., Sebo, P., Kuta Smatanova, I.
PDB entry 5edk: Crystal structure of prothrombin deletion mutant residues 146-167 ( Form II ).
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.214 Å
Deposited: 2015-10-21
Authors: Pozzi, N., Chen, Z., Di Cera, E.
PDB entry 5edl: Crystal structure of an S-component of ECF transporter
Classification: TRANSPORT PROTEIN
Source organism: Bacillus subtilis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2015-10-21
Authors: Josts, I., Tidow, H.
PDB entry 5edm: Crystal structure of prothrombin deletion mutant residues 154-167 ( Form I )
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2015-10-21
Authors: Pozzi, N., Chen, Z., Di Cera, E.
PDB entry 5edn: Structure of HOXB13-DNA(TCG) complex
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2 Å
Deposited: 2015-10-21
Authors: Morgunova, E., Yin, Y., Jolma, A., Popov, A., Taipale, J.
PDB entry 5edp: EGFR kinase (T790M/L858R) apo
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2015-10-21
Authors: Eigenbrot, C., Yu, C.
PDB entry 5edq: EGFR kinase (T790M/L858R) with inhibitor compound 15: ~{N}-(7-chloranyl-1~{H}-indazol-3-yl)-7,7-dimethyl-2-(1~{H}-pyrazol-4-yl)-5~{H}-furo[3,4-d]pyrimidin-4-amine
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2015-10-21
Authors: Eigenbrot, C., Yu, C.
PDB entry 5edr: EGFR kinase (T790M/L858R) with inhibitor compound 27: ~{N}-(1~{H}-indazol-3-yl)-7,7-dimethyl-2-(2-methylpyrazol-3-yl)-5~{H}-furo[3,4-d]pyrimidin-4-amine
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-10-21
Authors: Eigenbrot, C., Yu, C.
PDB entry 5eds: Crystal structure of human PI3K-gamma in complex with benzimidazole inhibitor 5
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2015-10-21
Authors: Whittington, D.A., Tang, J., Yakowec, P.
PDB entry 5edt: Crystal structure of Mycobacterium tuberculosis CYP121 in complex with LIG9
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium tuberculosis H37Rv
Experimental method: X-RAY DIFFRACTION
Resolution: 2.45 Å
Deposited: 2015-10-22
Authors: Kavanagh, M.E., Coyne, A.G., McLean, K.J., James, G.G., Levy, C., Marino, L.B., Carvalho, L.P.D., Chan, D.S.H., Hudson, S.A., Surade, S., Munro, A.W., Abell, C.
PDB entry 5edu: Crystal structure of human histone deacetylase 6 catalytic domain 2 in complex with trichostatin A
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Escherichia coli; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.79 Å
Deposited: 2015-10-22
Authors: Hai, Y., Christianson, D.W.
PDB entry 5edv: Structure of the HOIP-RBR/UbcH5B~ubiquitin transfer complex
Classification: LIGASE/TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.48 Å
Deposited: 2015-10-22
Authors: Lechtenberg, B.C., Mace, P.D., Sanishvili, R., Riedl, S.J.
PDB entry 5edw: Ternary structure of Dpo4 bound to G in the template base paired with incoming dTTP
Classification: transferase/dna
Source organism: Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.62 Å
Deposited: 2015-10-22
Authors: Koag, M.-C., Lee, S.
PDB entry 5edx: Crystal structure of swine CD8aa homodimer
Classification: IMMUNE SYSTEM
Source organism: Sus scrofa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.801 Å
Deposited: 2015-10-22
Authors: Liu, Y.J., Qi, J.X., Zhang, N.Z., Xia, C.
PDB entry 5ee0: Crystal structure of OsYchF1 at pH 6.5
Classification: HYDROLASE
Source organism: Oryza sativa subsp. japonica
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2015-10-22
Authors: Li, X., Chen, Z.
PDB entry 5ee1: Crystal structure of OsYchF1 at pH 7.85
Classification: HYDROLASE
Source organism: Oryza sativa subsp. japonica
Experimental method: X-RAY DIFFRACTION
Resolution: 2.55 Å
Deposited: 2015-10-22
Authors: Li, X., Chen, Z.
PDB entry 5ee2: The crystal structure of the C-terminal beta-barrel of HpuA from Neisseria gonorrhoeae
Classification: METAL TRANSPORT
Source organism: Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2015-10-22
Authors: Wong, C.T., Hare, S.A.
PDB entry 5ee3: COMPLEX STRUCTURE OF OSYCHF1 WITH AMP-PNP
Classification: HYDROLASE
Source organism: Oryza sativa subsp. japonica
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2015-10-22
Authors: Li, X., Chen, Z.
PDB entry 5ee4: The crystal structure of HpuA from Kingella denitrificans in complex with human haemoglobin
Classification: METAL TRANSPORT
Source organism: Homo sapiens; Kingella denitrificans ATCC 33394
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2015-10-22
Authors: Wong, C.T., Hare, S.A.
PDB entry 5ee5: Structure of human ARL1 in complex with the DCB domain of BIG1
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.279 Å
Deposited: 2015-10-22
Authors: Galindo, A., Soler, N., Munro, S.
PDB entry 5ee7: Crystal structure of the human glucagon receptor (GCGR) in complex with the antagonist MK-0893
Classification: SIGNALING PROTEIN
Source organism: Enterobacteria phage T4; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2015-10-22
Authors: Jazayeri, A., Dore, A.S., Lamb, D., Krishnamurthy, H., Southall, S.M., Baig, A.H., Bortolato, A., Koglin, M., Robertson, N.J., Errey, J.C., Andrews, S.P., Brown, A.J.H., Cooke, R.M., Weir, M., Marshall, F.H.
PDB entry 5ee8: Crystal structure of S02030 boronic acid inhibitor complexed to SHV-1 beta-lactamase
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Klebsiella pneumoniae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.54 Å
Deposited: 2015-10-22
Authors: Krishnan, N., van den Akker, F.
PDB entry 5ee9: Complex structure of OSYCHF1 with GMP-PNP
Classification: HYDROLASE
Source organism: Oryza sativa subsp. japonica
Experimental method: X-RAY DIFFRACTION
Resolution: 2.75 Å
Deposited: 2015-10-22
Authors: Li, X., Chen, Z.
PDB entry 5eea: Structure of HOXB13-DNA(CAA) complex
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.195 Å
Deposited: 2015-10-22
Authors: Morgunova, E., Yin, Y., Jolma, A., Popov, A., Taipale, J.
PDB entry 5eeb: Apo form of thermostable aldehyde dehydrogenase from Pyrobaculum sp. 1860
Classification: OXIDOREDUCTASE
Source organism: Pyrobaculum ferrireducens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.038 Å
Deposited: 2015-10-22
Authors: Petrova, T.E., Bezsudnova, E.Y., Boyko, K.M., Mardanov, A.V., Gumerov, V.M., Ravin, N.V., Popov, V.O.
PDB entry 5eec: Crystal structure of KPC-2 beta-lactamase in complex with the S02030 boronic acid inhibitor
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Klebsiella pneumoniae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.87 Å
Deposited: 2015-10-22
Authors: Nguyen, N.Q., van den Akker, F.
PDB entry 5eef: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 1 in complex with trichostatin A
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 2.151 Å
Deposited: 2015-10-22
Authors: Hai, Y., Christianson, D.W.
PDB entry 5eeg: Crystal structure of carminomycin-4-O-methyltransferase DnrK in complex with tetrazole-SAH
Classification: TRANSFERASE
Source organism: Streptomyces peucetius
Experimental method: X-RAY DIFFRACTION
Resolution: 2.255 Å
Deposited: 2015-10-22
Authors: Wang, F., Singh, S., Thorson, J.S., Phillips Jr., G.N., Enzyme Discovery for Natural Product Biosynthesis (NatPro)
PDB entry 5eeh: Crystal structure of carminomycin-4-O-methyltransferase DnrK in complex with SAH and 2-chloro-4-nitrophenol
Classification: TRANSFERASE
Source organism: Streptomyces peucetius
Experimental method: X-RAY DIFFRACTION
Resolution: 1.82 Å
Deposited: 2015-10-22
Authors: Wang, F., Singh, S., Thorson, J.S., Phillips Jr., G.N., Enzyme Discovery for Natural Product Biosynthesis (NatPro)
PDB entry 5eei: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with SAHA
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 1.32 Å
Deposited: 2015-10-22
Authors: Hai, Y., Christianson, D.W.
PDB entry 5eek: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with trichostatin A
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 1.59 Å
Deposited: 2015-10-23
Authors: Hai, Y., Christianson, D.W.
PDB entry 5eel: Grb7 SH2 with bicyclic peptide inhibitor
Classification: Signaling Protein/Peptide
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.47 Å
Deposited: 2015-10-23
Authors: Watson, G.M., Gunzburg, M.J., Wilce, M.C.J., Wilce, J.A.
PDB entry 5eem: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2
Classification: HYDROLASE
Source organism: Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-10-23
Authors: Hai, Y., Christianson, D.W.
PDB entry 5een: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with belinostat
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 1.861 Å
Deposited: 2015-10-23
Authors: Hai, Y., Christianson, D.W.
PDB entry 5eeo: soybean lipoxygenase(L1)-T756R
Classification: OXIDOREDUCTASE
Source organism: Glycine max
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2015-10-23
Authors: Mikami, B., Nagaya, T., Hioki, Y.
PDB entry 5eep: Crystal structure of E. coli CsdE
Classification: LIGASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2015-10-23
Authors: Park, S.Y.
PDB entry 5eeq: Grb7 SH2 with the G7-B1 bicyclic peptide inhibitor
Classification: Signaling Protein/Inhibitor
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2015-10-23
Authors: Ambaye, N.D., Watson, G.M., Wilce, M.C.J., Wilce, G.M.
PDB entry 5eer: Crystal structure of DapB from Corynebacterium glutamicum
Classification: OXIDOREDUCTASE
Source organism: Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2015-10-23
Authors: Sagong, H.-Y., Kim, K.-J.
PDB entry 5ees: Crystal structure of DapB in complex with NADP+ from Corynebacterium glutamicum
Classification: OXIDOREDUCTASE
Source organism: Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2015-10-23
Authors: Sagong, H.-Y., Kim, K.-J.
PDB entry 5eet: Crystal structure of murine neuroglobin at ambient pressure
Classification: TRANSPORT PROTEIN
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-10-23
Authors: Colloc'h, N., Girard, E., Vallone, B.
PDB entry 5eeu: RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 1.31 MGy
Classification: RNA BINDING PROTEIN
Source organism: Geobacillus stearothermophilus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2015-10-23
Authors: Bury, C.S., McGeehan, J.E., Garman, E.F., Shevtsov, M.B.
PDB entry 5eev: RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 3.88 MGy
Classification: RNA BINDING PROTEIN
Source organism: Geobacillus stearothermophilus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2015-10-23
Authors: Bury, C.S., McGeehan, J.E., Garman, E.F., Shevtsov, M.B.
PDB entry 5eew: RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 6.45 MGy
Classification: RNA BINDING PROTEIN
Source organism: Geobacillus stearothermophilus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2015-10-23
Authors: Bury, C.S., McGeehan, J.E., Garman, E.F., Shevtsov, M.B.
PDB entry 5eex: RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 9.02 MGy
Classification: RNA BINDING PROTEIN
Source organism: Geobacillus stearothermophilus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2015-10-23
Authors: Bury, C.S., McGeehan, J.E., Garman, E.F., Shevtsov, M.B.
PDB entry 5eey: RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 11.6 MGy
Classification: RNA BINDING PROTEIN
Source organism: Geobacillus stearothermophilus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2015-10-23
Authors: Bury, C.S., McGeehan, J.E., Garman, E.F., Shevtsov, M.B.
PDB entry 5eez: RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 14.2 MGy
Classification: RNA BINDING PROTEIN
Source organism: Geobacillus stearothermophilus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2015-10-23
Authors: Bury, C.S., McGeehan, J.E., Garman, E.F., Shevtsov, M.B.
PDB entry 5ef0: RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 16.7 MGy
Classification: RNA BINDING PROTEIN
Source organism: Geobacillus stearothermophilus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2015-10-23
Authors: Bury, C.S., McGeehan, J.E., Garman, E.F., Shevtsov, M.B.
PDB entry 5ef1: RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 19.3 MGy
Classification: RNA BINDING PROTEIN
Source organism: Geobacillus stearothermophilus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2015-10-23
Authors: Bury, C.S., McGeehan, J.E., Garman, E.F., Shevtsov, M.B.
PDB entry 5ef2: RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 21.9 MGy
Classification: RNA BINDING PROTEIN
Source organism: Geobacillus stearothermophilus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2015-10-23
Authors: Bury, C.S., McGeehan, J.E., Garman, E.F., Shevtsov, M.B.
PDB entry 5ef3: RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 25.0 MGy
Classification: RNA BINDING PROTEIN
Source organism: Geobacillus stearothermophilus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2015-10-23
Authors: Bury, C.S., McGeehan, J.E., Garman, E.F., Shevtsov, M.B.
PDB entry 5ef4: 2.05 A crystal structure of the Amb a 11 cysteine protease, a major ragweed pollen allergen, in its proform
Classification: ALLERGEN
Source organism: Ambrosia artemisiifolia
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2015-10-23
Authors: Briozzo, P., Kopecny, D., Savko, M.
PDB entry 5ef5: Crystal structure of Chaetomium thermophilum Raptor
Classification: SIGNALING PROTEIN
Source organism: Chaetomium thermophilum
Experimental method: X-RAY DIFFRACTION
Resolution: 4.3 Å
Deposited: 2015-10-23
Authors: Imseng, S., Sauer, E., Aylett, C.H.S., Boehringer, D., Hall, M.N., Ban, N., Maier, T.
PDB entry 5ef6: Structure of HOXB13 complex with methylated DNA
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2015-10-23
Authors: Morgunova, E., Yin, Y., Jolma, A., Popov, A., Taipale, J.
PDB entry 5ef7: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with HPOB
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2015-10-23
Authors: Hai, Y., Christianson, D.W.
PDB entry 5ef8: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with panobinostat
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-10-23
Authors: Hai, Y., Christianson, D.W.
PDB entry 5ef9: Structure of Influenza B Lee PB2 cap-binding domain
Classification: PROTEIN BINDING
Source organism: Influenza B virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2015-10-23
Authors: Ma, X., Shia, S.
PDB entry 5efa: Structure of Influenza B Lee PB2 cap-binding domain bound to m7GTP
Classification: PROTEIN BINDING
Source organism: Influenza B virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2015-10-23
Authors: Ma, X., Shia, S.
PDB entry 5efb: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with oxamflatin
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 2.543 Å
Deposited: 2015-10-23
Authors: Hai, Y., Christianson, D.W.
PDB entry 5efc: Structure of Influenza B Lee PB2 cap-binding domain bound to GTP
Classification: PROTEIN BINDING
Source organism: Influenza B virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2015-10-23
Authors: Ma, X., Shia, S.
PDB entry 5efd: Crystal structure of a surface pocket creating mutant (W6A) of an alkali thermostable GH10 xylanase from Bacillus sp. NG-27
Classification: HYDROLASE
Source organism: Bacillus sp. NG-27
Experimental method: X-RAY DIFFRACTION
Resolution: 1.674 Å
Deposited: 2015-10-23
Authors: Mahanta, P., Bhardwaj, A., Reddy, V.S., Ramakumar, S.
PDB entry 5eff: Crystal structure of an aromatic mutant (F4A) of an alkali thermostable GH10 xylanase from Bacillus sp. NG-27
Classification: HYDROLASE
Source organism: Bacillus sp. NG-27
Experimental method: X-RAY DIFFRACTION
Resolution: 2.23 Å
Deposited: 2015-10-23
Authors: Mahanta, P., Bhardwaj, A., Reddy, V.S., Ramakumar, S.
PDB entry 5efg: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with acetate
Classification: HYDROLASE
Source organism: Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2015-10-23
Authors: Hai, Y., Christianson, D.W.
PDB entry 5efh: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with trifluoroketone transition state analogue
Classification: HYDROLASE
Source organism: Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 2.162 Å
Deposited: 2015-10-23
Authors: Hai, Y., Christianson, D.W.
PDB entry 5efi: Crystal structure of mouse CD1d in complex with the p99p lipopeptide
Classification: IMMUNE SYSTEM
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2015-10-23
Authors: Girardi, E., Wang, J., Zajonc, D.M.
PDB entry 5efj: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with HC toxin
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Bipolaris zeicola; Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 1.73 Å
Deposited: 2015-10-23
Authors: Hai, Y., Christianson, D.W.
PDB entry 5efk: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 (Y745F mutant) in complex with alpha tubulin K40 tripeptide substrate
Classification: HYDROLASE
Source organism: Danio rerio
Experimental method: X-RAY DIFFRACTION
Resolution: 1.82 Å
Deposited: 2015-10-23
Authors: Hai, Y., Christianson, D.W.
PDB entry 5efm: Beclin 1 Flexible-helical Domian (FHD) (141-171)
Classification: APOPTOSIS
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2015-10-23
Authors: Sinha, S., Mei, Y.
PDB entry 5efn: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 (H574A) in complex with histone H4 Lys6 tripeptide substrate
Classification: HYDROLASE
Source organism: Danio rerio; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.804 Å
Deposited: 2015-10-24
Authors: Hai, Y., Christianson, D.W.
PDB entry 5efo: X-ray structure uridine phosphorylase from Vibrio cholerae in complex with cytidine and cytosine at 1.63A.
Classification: TRANSFERASE
Source organism: Vibrio cholerae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.63 Å
Deposited: 2015-10-24
Authors: Prokofev, I.I., Lashkov, A.A., Gabdoulkhakov, A.G., Betzel, C., Mikhailov, A.M.
PDB entry 5efq: Crystal structure of human Cdk13/Cyclin K in complex with ADP-aluminum fluoride
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-10-24
Authors: Hoenig, D., Greifenberg, A.K., Anand, K., Geyer, M.
PDB entry 5efr: Crystal Structure of a BamA-BamD fusion
Classification: CELL ADHESION
Source organism: Rhodothermus marinus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-10-24
Authors: Bergal, H.T., Hopkins, A.H., Metzner, S.I., Sousa, M.C.
PDB entry 5efs: The crystal structure of human kynurenine aminotransferase II
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.82503 Å
Deposited: 2015-10-26
Authors: Nematollahi, A., Sun, G., Kwan, A., Harrop, S.J., Hanrahan, J.R., Nadvi, N.A., Church, W.B.
PDB entry 5eft: Structural Basis for Specific Recognition of ssDNA by SRBSDV P9-1 Octamers
Classification: VIRAL PROTEIN
Source organism: Rice black-streaked dwarf virus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2015-10-26
Authors: Li, X.Y.
PDB entry 5efu: Resting state of rat cysteine dioxygenase H155Q variant
Classification: OXIDOREDUCTASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2015-10-26
Authors: Fellner, M., Tchesnokov, E.P., Jameson, G.N.L., Wilbanks, S.M.
PDB entry 5efv: The host-recognition device of Staphylococcus aureus phage Phi11
Classification: STRUCTURAL PROTEIN
Source organism: Staphylococcus phage phi11
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2015-10-26
Authors: Koc, C., Kuhner, P., Xia, G., Spinelli, S., Roussel, A., Cambillau, C., Stehle, T.
PDB entry 5efw: Crystal structure of LOV2-Zdk1 - the complex of oat LOV2 and the affibody protein Zdark1
Classification: SIGNALING PROTEIN
Source organism: Avena sativa; Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2015-10-26
Authors: Winkler, A., Wang, H., Hartmann, E., Hahn, K., Schlichting, I.
PDB entry 5efx: Crystal structure of Rho GTPase regulator
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.451 Å
Deposited: 2015-10-26
Authors: Jiang, Y., Ouyang, S., Liu, Z.J.
PDB entry 5efy: Apo-form of SCO3201
Classification: TRANSCRIPTION
Source organism: Streptomyces coelicolor
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2015-10-26
Authors: Waack, P., Hinrichs, W.
PDB entry 5efz: Monoclinic structure of the acetyl esterase MekB
Classification: HYDROLASE
Source organism: Pseudomonas veronii
Experimental method: X-RAY DIFFRACTION
Resolution: 1.82 Å
Deposited: 2015-10-26
Authors: Toelzer, C., Pal, S., Watzlawick, H., Altenbuchner, J., Niefind, K.
PDB entry 5eg0: HOXB13-MEIS1 heterodimer bound to DNA
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.101 Å
Deposited: 2015-10-26
Authors: Morgunova, E., Yin, Y., Jolma, A., Popov, A., Taipale, J.
PDB entry 5eg1: Antibacterial peptide ABC transporter McjD with a resolved lipid
Classification: TRANSPORT PROTEIN
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 3.42 Å
Deposited: 2015-10-26
Authors: Choudhury, H.G., Beis, K.
PDB entry 5eg2: SET7/9 N265A in complex with AdoHcy and TAF10 peptide
Classification: Transferase/Transcription Factor
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2015-10-26
Authors: Kroner, G.M., Fick, R.J., Trievel, R.C.
PDB entry 5eg3: Crystal Structure of the Activated FGF Receptor 2 (FGFR2) Kinase Domain in complex with the cSH2 domain of Phospholipase C gamma (PLCgamma)
Classification: Transferase/Hydrolase
Source organism: Homo sapiens; Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.606 Å
Deposited: 2015-10-26
Authors: Huang, Z., Li, X., Mohammadi, M.
PDB entry 5eg4: BOVINE TRYPSIN IN COMPLEX WITH CYCLIC INHIBITOR
Classification: HYDROLASE
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.32 Å
Deposited: 2015-10-26
Authors: Knoerlein, A., Wagner, S., Heine, A., Steinmetzer, T., Klebe, G.
PDB entry 5eg5: As (III) S-adenosylmethyltransferase cysteine mutant C72A bound Phenylarsine oxide (PhAs(III) in the arsenic binding site
Classification: TRANSFERASE
Source organism: Cyanidioschyzon sp. 5508
Experimental method: X-RAY DIFFRACTION
Resolution: 1.97 Å
Deposited: 2015-10-26
Authors: Packianathan, C., Marapakala, K., Kandavelu, P., Rosen, B.P.
PDB entry 5eg6: CSL-RITA complex bound to DNA
Classification: TRANSCRIPTION/DNA BINDING PROTEIN/DNA
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.094 Å
Deposited: 2015-10-26
Authors: Tabaja, N.H., Kovall, R.A.
PDB entry 5eg7: The cap binding site of influenza virus protein PB2 as a drug target
Classification: VIRAL PROTEIN
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2015-10-26
Authors: Severin, C., Rocha de Moura, T., Liu, Y., Li, K., Zheng, X., Luo, M.
PDB entry 5eg8: The cap binding site of influenza virus protein PB2 as a drug target
Classification: VIRAL PROTEIN
Source organism: Influenza A virus (A/swine/Quebec/1257777/2010(H3N2))
Experimental method: X-RAY DIFFRACTION
Resolution: 1.54 Å
Deposited: 2015-10-26
Authors: Liu, Y., Zheng, X., Severin, C., Rocha de Moura, T., Li, K., Luo, M.
PDB entry 5eg9: The cap binding site of influenza virus protein PB2 as a drug target
Classification: VIRAL PROTEIN
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2015-10-26
Authors: Severin, C., Rocha de Moura, T., Liu, Y., Li, K., Zheng, X., Luo, M.
PDB entry 5ega: 2009 H1N1 PA endonuclease domain in complex with an N-acylhydrazone inhibitor
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2015-10-26
Authors: Kumar, G., White, S.W.
PDB entry 5egb: Human PRDM9 allele-A ZnF Domain with Associated Recombination Hotspot DNA Sequence II
Classification: TRANSCRIPTION/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.977 Å
Deposited: 2015-10-26
Authors: Patel, A., Horton, J.R., Wilson, G.G., Zhang, X., Cheng, X.
PDB entry 5egc: Structure of the Adeno-Associated Virus Serotype 1 sialic acid complex
Classification: VIRUS
Source organism: Adeno-associated virus - 1
Experimental method: X-RAY DIFFRACTION
Resolution: 3.011 Å
Deposited: 2015-10-27
Authors: Huang, L.Y., Agbandje-McKenna, M.
PDB entry 5ege: Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase
Classification: HYDROLASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-10-27
Authors: Morita, J., Kano, K., Kato, K., Takita, H., Ishitani, R., Nishimasu, H., Nureki, O., Aoki, J.
PDB entry 5egf: The crystal structure of SeMet-CT
Classification: UNKNOWN FUNCTION
Source organism: Penicillium aethiopicum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.29 Å
Deposited: 2015-10-27
Authors: Zhang, J.R., Tang, Y., Zhou, J.H.
PDB entry 5egg: Crystal structure of human ubiquitin-conjugating enzyme UBCH5C
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.76 Å
Deposited: 2015-10-27
Authors: Zhu, L., Li, H., Wu, F., Zhu, J.
PDB entry 5egh: Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase in complex with phosphocholine
Classification: HYDROLASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.803 Å
Deposited: 2015-10-27
Authors: Morita, J., Kano, K., Kato, K., Takita, H., Ishitani, R., Nishimasu, H., Nureki, O., Aoki, J.
PDB entry 5egi: Structure of a Trimeric Intracellular Cation channel from C. elegans with bound Ca2+
Classification: MEMBRANE PROTEIN
Source organism: Caenorhabditis elegans
Experimental method: X-RAY DIFFRACTION
Resolution: 3.3 Å
Deposited: 2015-10-27
Authors: Yang, H.T., Hu, M.H., Liu, Z.F.
PDB entry 5egj: The structural and biochemical characterization of acyl-coa hydrolase mutant Asn28Ala from Staphylococcus aureus in complex with COENZYME A
Classification: HYDROLASE
Source organism: Staphylococcus aureus (strain Mu50 / ATCC 700699)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2015-10-27
Authors: Khandokar, Y.B., Srivastava, P.S., Forwood, J.K.
PDB entry 5egk: The structural and biochemical characterization of acyl-coa hydrolase mutant Asp43Ala from Staphylococcus aureus
Classification: HYDROLASE
Source organism: Staphylococcus aureus (strain Mu50 / ATCC 700699)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2015-10-27
Authors: Khandokar, Y.B., Srivastava, P.S., Forwood, J.K.
PDB entry 5egl: The structural and biochemical characterization of acyl-coa hydrolase from Staphylococcus aureus in complex with Butyryl Coenzyme A, Coenzyme A, and Coenzyme A disulfide
Classification: HYDROLASE
Source organism: Staphylococcus aureus (strain Mu50 / ATCC 700699)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2015-10-27
Authors: Khandokar, Y.B., Srivastava, P.S., Forwood, J.K.
PDB entry 5egm: Development of a novel tricyclic class of potent and selective FIXa inhibitors
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.841 Å
Deposited: 2015-10-27
Authors: Meng, D., Andre, P., Bateman, T.J., Berger, R., Chen, Y., Desai, K., Dewnani, S., Ellsworth, K., Feng, D., Geissler, W.M., Guo, L., Hruza, A., Jian, T., Li, H., Parker, D.L., Reichert, P., Sherer, E.C., Smith, C.J., Sonatore, L.M., Tschirret-Guth, R., Wu, J., Xu, J., Zhang, T., Campeau, L., Orr, R., Poirier, M., McCabe-Dunn, j., Araki, K., Nishimura, T., Sakurada, I., Hirabayashi, T., Wood, H.B.
PDB entry 5egn: Est816 as an N-Acyl homoserine lactone degrading enzyme
Classification: HYDROLASE
Source organism: uncultured bacterium
Experimental method: X-RAY DIFFRACTION
Resolution: 2.636 Å
Deposited: 2015-10-27
Authors: Xie, W., Liu, X., Cao, L., Liu, Y.
PDB entry 5ego: HOXB13-MEIS1 heterodimer bound to methylated DNA
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.54 Å
Deposited: 2015-10-27
Authors: Morgunova, E., Yin, Y., Jolma, A., Popov, A., Taipale, J.
PDB entry 5egp: Crystal structure of the S-methyltransferase TmtA
Classification: TRANSFERASE
Source organism: Aspergillus fumigatus Z5
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2015-10-27
Authors: Duell, E.R., Glaser, M., Antes, I., Groll, M., Huber, E.M.
PDB entry 5egq: Structure of tetrameric rat phenylalanine hydroxylase mutant R270K, residues 25-453
Classification: OXIDOREDUCTASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2015-10-27
Authors: Taylor, A.B., Khan, C.A., Fitzpatrick, P.F.
PDB entry 5egr: tRNA guanine transglycosylase (TGT) in complex with an Immucillin derivative
Classification: TRANSFERASE
Source organism: Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2015-10-27
Authors: Ehrmann, F.R., Heine, A., Klebe, G.
PDB entry 5egs: Human PRMT6 with bound fragment-type inhibitor
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2015-10-27
Authors: Steuber, H., Egner, U., Kania, J., Wu, H., Brown, P.J.
PDB entry 5egt: Crystal structure of Staphylococcal nuclease variant Delta+PHS V66E at cryogenic temperature
Classification: HYDROLASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2015-10-27
Authors: Skerritt, L.A., Bell-Upp, P.C., Siegler, M.A., Schlessman, J.L., Garcia-Moreno E., B.
PDB entry 5egu: FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR 3-Butyl-8-(6-butyl-5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylsulfanylmethyl)-7-ethyl-3,7-dihydropurine-2,6-dione
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.21 Å
Deposited: 2015-10-27
Authors: Raux, B., Rebuffet, E., Betzi, S., Priet, S., Morelli, X.
PDB entry 5egv: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex the 3,4-diaryl-furan derivative 3-chloranyl-4-[4-(2-chloranyl-4-oxidanyl-phenyl)furan-3-yl]phenol
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.863 Å
Deposited: 2015-10-27
Authors: Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
PDB entry 5egw: 2.70 A crystal structure of the Amb a 11 cysteine protease, a major ragweed pollen allergen, in its proform
Classification: ALLERGEN
Source organism: Ambrosia artemisiifolia
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2015-10-27
Authors: Briozzo, P., Kopecny, D.
PDB entry 5egy: Structure of ligand free human DPP3 in closed form.
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.741 Å
Deposited: 2015-10-27
Authors: Kumar, P., Reithofer, V., Reisinger, M., Pavkov-Keller, T., Wallner, S., Macheroux, P., Gruber, K.
PDB entry 5eh0: Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.18 Å
Deposited: 2015-10-27
Authors: Innocenti, P., Woodward, H.L., Solanki, S., Naud, N., Westwood, I.M., Cronin, N., Hayes, A., Roberts, J., Henley, A.T., Baker, R., Faisal, A., Mak, G., Box, G., Valenti, M., De Haven Brandon, A., O'Fee, L., Saville, J., Schmitt, J., Burke, R., van Montfort, R.L.M., Raymaud, F.I., Eccles, S.A., Linardopoulos, S., Blagg, J., Hoelder, S.
PDB entry 5eh1: Crystal structure of the extracellular part of receptor 2 of human interferon gamma
Classification: CYTOKINE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2015-10-27
Authors: Kolenko, P., Mikulecky, P., Zahradnik, J., Dohnalek, J., Koval, T., Cerny, J., Necasova, I., Schneider, B.
PDB entry 5eh2: Human PRDM9 allele-A ZnF Domain with Associated Recombination Hotspot DNA Sequence III
Classification: TRANSCRIPTION/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2015-10-27
Authors: Patel, A., Horton, J.R., Wilson, G.G., Zhang, X., Cheng, X.
PDB entry 5eh4: Crystal Structure of the Glycophorin A Transmembrane Dimer in Lipidic Cubic Phase
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.81 Å
Deposited: 2015-10-28
Authors: Call, M.J., Call, M.E., Trenker, R.
PDB entry 5eh5: human carbonic anhydrase II in complex with ligand
Classification: LYASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.207 Å
Deposited: 2015-10-28
Authors: Ren, B.
PDB entry 5eh6: Crystal Structure of the Glycophorin A Transmembrane Monomer in Lipidic Cubic Phase
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.918 Å
Deposited: 2015-10-28
Authors: Call, M.J., Call, M.E., Trenker, R.
PDB entry 5eh7: human carbonic anhydrase II in complex with ligand
Classification: LYASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.425 Å
Deposited: 2015-10-28
Authors: Ren, B.
PDB entry 5eh8: human carbonic anhydrase II in complex with ligand
Classification: LYASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.381 Å
Deposited: 2015-10-28
Authors: Ren, B.
PDB entry 5eh9: Indirect contributions of mutations underlie optimization of new enzyme function
Classification: HYDROLASE
Source organism: Bacillus thuringiensis subsp. kurstaki
Experimental method: X-RAY DIFFRACTION
Resolution: 1.29 Å
Deposited: 2015-10-28
Authors: Hong, N.-S., Jackson, C.J., Tokuriki, N., Yang, G., Baier, F.
PDB entry 5eha: Crystal structure of recombinant MtaL at 1.35 Angstrom resolution
Classification: HYDROLASE
Source organism: Agaricus bisporus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.35 Å
Deposited: 2015-10-28
Authors: Lai, X.-L., Soler-Lopez, M., Wichers, H.J., Dijkstra, B.W.
PDB entry 5ehb: A de novo designed hexameric coiled-coil peptide with iodotyrosine
Classification: DE NOVO PROTEIN
Experimental method: X-RAY DIFFRACTION
Resolution: 3.19 Å
Deposited: 2015-10-28
Authors: Lizatovic, R., Aurelius, O., Stenstrom, O., Drakenberg, T., Akke, M., Logan, D.T., Andre, I.
PDB entry 5ehc: Co-crystal structure of eIF4E with nucleotide mimetic inhibitor.
Classification: TRANSLATION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2015-10-28
Authors: Nowicki, M.W., Walkinshaw, M.D., Fischer, P.M.
PDB entry 5ehd: Crystal structure of human nucleophosmin-core in complex with cytochrome c
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.55 Å
Deposited: 2015-10-28
Authors: Bernardo-Garcia, N., Hermoso, J.A., Gonzalez-Arzola, K., Diaz-Moreno, I., De la Rosa, M.A.
PDB entry 5ehe: Crystal structure of human carbonic anhydrase isozyme II with 3-(benzylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide
Classification: LYASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2015-10-28
Authors: Smirnov, A., Manakova, E., Grazulis, S.
PDB entry 5ehf: Laccase from Antrodiella faginea
Classification: OXIDOREDUCTASE
Source organism: Antrodiella faginea
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2015-10-28
Authors: Polyakov, K.M., Glazunova, O.A., Fedorova, T.V., Dorovatovskii, P.V., Koroleva, O.V.
PDB entry 5ehg: DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO S-ADENOSYL METHIONINE AND MOLECULE BF341
Classification: TRANSFERASE
Source organism: Dengue virus type 3 (strain Philippines/H87/1956)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.02 Å
Deposited: 2015-10-28
Authors: Barral, K., Bricogne, G., Sharff, A.
PDB entry 5ehh: Structure of human DPP3 in complex with endomorphin-2.
Classification: HYDROLASE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.38 Å
Deposited: 2015-10-28
Authors: Kumar, P., Reithofer, V., Reisinger, M., Pavkov-Keller, T., Wallner, S., Macheroux, P., Gruber, K.
PDB entry 5ehi: DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO S-ADENOSYL METHIONINE AND MOLECULE BF287
Classification: TRANSFERASE
Source organism: Dengue virus type 3 (strain Philippines/H87/1956)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.303 Å
Deposited: 2015-10-28
Authors: Barral, K., Bricogne, G., Sharff, A.
PDB entry 5ehj: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-[(4aR,8aR)-octahydronaphthalen-2(1H)-ylidenemethanediyl]diphenol
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2015-10-28
Authors: Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
PDB entry 5ehk: Crystal structure of tRNA dependent lantibiotic dehydratase MibB from Microbispora sp. 107891
Classification: HYDROLASE
Source organism: Microbispora corallina
Experimental method: X-RAY DIFFRACTION
Resolution: 2.708 Å
Deposited: 2015-10-28
Authors: Hao, Y., Nair, S.K.
PDB entry 5ehl: Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.66 Å
Deposited: 2015-10-28
Authors: Innocenti, P., Woodward, H.L., Solanki, S., Naud, N., Westwood, I.M., Cronin, N., Hayes, A., Roberts, J., Henley, A.T., Baker, R., Faisal, A., Mak, G., Box, G., Valenti, M., De Haven Brandon, A., O'Fee, L., Saville, J., Schmitt, J., Burke, R., van Montfort, R.L.M., Raymaud, F.I., Eccles, S.A., Linardopoulos, S., Blagg, J., Hoelder, S.
PDB entry 5ehm: Crystal structure of the Drosophila CG3822 KaiR1D ligand binding domain complex with NMDA
Classification: MEMBRANE PROTEIN
Source organism: Drosophila melanogaster
Experimental method: X-RAY DIFFRACTION
Resolution: 1.281 Å
Deposited: 2015-10-28
Authors: Dharkar, P., Mayer, M.L.
PDB entry 5ehn: mAChE-syn TZ2PA5 complex
Classification: HYDROLASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-10-28
Authors: Bourne, Y., Marchot, P.
PDB entry 5eho: Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.18 Å
Deposited: 2015-10-28
Authors: Innocenti, P., Woodward, H.L., Solanki, S., Naud, N., Westwood, I.M., Cronin, N., Hayes, A., Roberts, J., Henley, A.T., Baker, R., Faisal, A., Mak, G., Box, G., Valenti, M., De Haven Brandon, A., O'Fee, L., Saville, J., Schmitt, J., Burke, R., van Montfort, R.L.M., Raymaud, F.I., Eccles, S.A., Linardopoulos, S., Blagg, J., Hoelder, S.
PDB entry 5ehp: Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor SHP836
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2015-10-28
Authors: Stams, T., Fodor, M.
PDB entry 5ehq: mAChE-anti TZ2PA5 complex
Classification: HYDROLASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2015-10-28
Authors: Bourne, Y., Marchot, P.
PDB entry 5ehr: Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor SHP099
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2015-10-28
Authors: Stams, T., Fodor, M.
PDB entry 5ehs: Crystal structure of the Drosophila CG3822 KaiR1D ligand binding domain complex with D-AP5
Classification: MEMBRANE PROTEIN
Source organism: Drosophila grimshawi; Drosophila melanogaster
Experimental method: X-RAY DIFFRACTION
Resolution: 1.749 Å
Deposited: 2015-10-28
Authors: Dharkar, P., Mayer, M.L.
PDB entry 5eht: Indirect contributions of mutations underlie optimization of new enzyme function
Classification: HYDROLASE
Source organism: Bacillus thuringiensis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.29 Å
Deposited: 2015-10-28
Authors: Jackson, C.J., Hong, N.-S.
PDB entry 5ehu: sfGFP mutant with unnatural amino acid 4-azidoethoxy-L-phenylalanine incorporated at the 149 site
Classification: FLUORESCENT PROTEIN
Source organism: Aequorea victoria
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2015-10-28
Authors: Tookmanian, E.M., Phillips-Piro, C.M., Fenlon, E.E., Brewer, S.B.
PDB entry 5ehv: human carbonic anhydrase II in complex with ligand
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.208 Å
Deposited: 2015-10-29
Authors: Ren, B.
PDB entry 5ehw: human carbonic anhydrase II in complex with ligand
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.392 Å
Deposited: 2015-10-29
Authors: Ren, B.
PDB entry 5ehx: Crystal structure of MSF-aged Torpedo californica Acetylcholinesterase
Classification: HYDROLASE
Source organism: Torpedo californica
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2015-10-29
Authors: Pesaresi, A., Lamba, D.
PDB entry 5ehy: Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.26 Å
Deposited: 2015-10-29
Authors: Innocenti, P., Woodward, H.L., Solanki, S., Naud, N., Westwood, I.M., Cronin, N., Hayes, A., Roberts, J., Henley, A.T., Baker, R., Faisal, A., Mak, G., Box, G., Valenti, M., De Haven Brandon, A., O'Fee, L., Saville, J., Schmitt, J., Burke, R., van Montfort, R.L.M., Raymaud, F.I., Eccles, S.A., Linardopoulos, S., Blagg, J., Hoelder, S.
PDB entry 5ehz: mAChE-syn TZ2PA5 complex from an equimolar mixture of the syn/anti isomers
Classification: HYDROLASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2015-10-29
Authors: Bourne, Y., Marchot, P.