LiteFold/PDB huggingface dataset:
PDB entry 4mvu: Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel
Classification: METAL TRANSPORT
Source organism: Arcobacter butzleri
Experimental method: X-RAY DIFFRACTION
Resolution: 3.198 Å
Deposited: 2013-09-24
Authors: Tang, L., Gamal El-Din, T.M., Payandeh, J., Martinez, G.Q., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
PDB entry 4mvw: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1433)
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Trypanosoma brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.901 Å
Deposited: 2013-09-24
Authors: Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
PDB entry 4mvx: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-phenylurea (Chem 1356)
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Trypanosoma brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.55 Å
Deposited: 2013-09-24
Authors: Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
PDB entry 4mvy: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-(3-hydroxyphenyl)urea (Chem 1387)
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Trypanosoma brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.314 Å
Deposited: 2013-09-24
Authors: Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
PDB entry 4mvz: Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel
Classification: METAL TRANSPORT
Source organism: Arcobacter butzleri
Experimental method: X-RAY DIFFRACTION
Resolution: 3.3 Å
Deposited: 2013-09-24
Authors: Tang, L., Gamal El-Din, T.M., Payandeh, J., Martinez, G.Q., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
PDB entry 4mw0: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-(2-hydroxyphenyl)urea (Chem 1392)
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Trypanosoma brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.201 Å
Deposited: 2013-09-24
Authors: Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
PDB entry 4mw1: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3-chloro-5-methoxybenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1444)
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Trypanosoma brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.494 Å
Deposited: 2013-09-24
Authors: Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
PDB entry 4mw2: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-(3-{[5-chloro-2-hydroxy-3-(prop-2-en-1-yl)benzyl]amino}propyl)-3-thiophen-3-ylurea (Chem 1472)
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Trypanosoma brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2013-09-24
Authors: Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
PDB entry 4mw3: Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel
Classification: METAL TRANSPORT
Source organism: Arcobacter butzleri
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2997 Å
Deposited: 2013-09-24
Authors: Tang, L., Gamal El-Din, T.M., Payandeh, J., Martinez, G.Q., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
PDB entry 4mw4: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(5-chloro-2-hydroxy-3-iodobenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1473)
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Trypanosoma brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2013-09-24
Authors: Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
PDB entry 4mw5: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3-chloro-5-methoxybenzyl)amino]propyl}-3-phenylurea (Chem 1415)
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Trypanosoma brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.347 Å
Deposited: 2013-09-24
Authors: Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
PDB entry 4mw6: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-(3-{[2-(benzyloxy)-5-chloro-3-(prop-2-en-1-yl)benzyl]amino}propyl)-3-thiophen-3-ylurea (Chem 1476)
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Trypanosoma brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.558 Å
Deposited: 2013-09-24
Authors: Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
PDB entry 4mw7: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(5-chloro-2-ethoxy-3-iodobenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1469)
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Trypanosoma brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.75 Å
Deposited: 2013-09-24
Authors: Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
PDB entry 4mw8: Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel
Classification: METAL TRANSPORT
Source organism: Arcobacter butzleri
Experimental method: X-RAY DIFFRACTION
Resolution: 3.256 Å
Deposited: 2013-09-24
Authors: Tang, L., Gamal El-Din, T.M., Payandeh, J., Martinez, G.Q., Heard, T.M., Scheuer, T., Zheng, N., Catterall, W.A.
PDB entry 4mw9: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3-ethynylbenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1478)
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Trypanosoma brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.65 Å
Deposited: 2013-09-24
Authors: Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
PDB entry 4mwa: 1.85 Angstrom Crystal Structure of GCPE Protein from Bacillus anthracis
Classification: OXIDOREDUCTASE
Source organism: Bacillus anthracis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2013-09-24
Authors: Minasov, G., Wawrzak, Z., Brunzelle, J.S., Xu, X., Cui, H., Maltseva, N., Bishop, B., Kwon, K., Savchenko, A., Joachimiak, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4mwb: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-(3-{[(2,5-dichlorothiophen-3-yl)methyl]amino}propyl)-3-thiophen-3-ylurea (Chem 1509)
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Trypanosoma brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.313 Å
Deposited: 2013-09-24
Authors: Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
PDB entry 4mwc: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-(3-{[(2-methyl-1-benzothiophen-3-yl)methyl]amino}propyl)-3-thiophen-3-ylurea (Chem 1540)
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Trypanosoma brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.649 Å
Deposited: 2013-09-24
Authors: Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
PDB entry 4mwd: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1433) and ATP analog AMPPCP
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Trypanosoma brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.253 Å
Deposited: 2013-09-24
Authors: Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
PDB entry 4mwe: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-(3-{[5-chloro-3-(prop-2-en-1-yl)-2-(prop-2-en-1-yloxy)benzyl]amino}propyl)-3-thiophen-3-ylurea (Chem 1475)
Classification: LIGASE/LIGASE INHIBITOR
Source organism: Trypanosoma brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 2.45 Å
Deposited: 2013-09-24
Authors: Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
PDB entry 4mwf: Structure of Hepatitis C Virus Envelope Glycoprotein E2 core bound to broadly neutralizing antibody AR3C
Classification: IMMUNE SYSTEM
Source organism: Hepatitis C virus (isolate H); Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.645 Å
Deposited: 2013-09-24
Authors: Kong, L., Wilson, I.A., Law, M.
PDB entry 4mwg: Crystal structure of Burkholderia xenovorans DmrB apo form: A Cubic Protein Cage for Redox Transfer
Classification: OXIDOREDUCTASE
Source organism: Burkholderia xenovorans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2013-09-24
Authors: Bobik, T.A., Cascio, D., Jorda, J., McNamara, D.E., Bustos, C., Wang, T.C., Rasche, M.E., Yeates, T.O.
PDB entry 4mwh: Crystal structure of scCK2 alpha in complex with ATP
Classification: TRANSFERASE
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.09 Å
Deposited: 2013-09-24
Authors: Liu, H.
PDB entry 4mwi: Crystal structure of the human MLKL pseudokinase domain
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2013-09-25
Authors: Czabotar, P.E., Murphy, J.M.
PDB entry 4mwj: Anhui N9
Classification: HYDROLASE
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-09-25
Authors: Wu, Y., Qi, J.X., Gao, F., Gao, G.F.
PDB entry 4mwl: Shanghai N9
Classification: HYDROLASE
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-09-25
Authors: Wu, Y., Qi, J.X., Gao, F., Gao, G.F.
PDB entry 4mwo: Crystal structure of human mitochondrial 5'(3')-deoxyribonucleotidase in complex with the inhibitor CPB-T
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.67 Å
Deposited: 2013-09-25
Authors: Pachl, P., Rezacova, P., Brynda, J.
PDB entry 4mwp: Thermolysin in complex with UBTLN46
Classification: hydrolase/hydrolase inhibitor
Source organism: Bacillus thermoproteolyticus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.23 Å
Deposited: 2013-09-25
Authors: Krimmer, S.G., Heine, A., Klebe, G.
PDB entry 4mwq: Anhui N9-oseltamivir carboxylate
Classification: HYDROLASE
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2013-09-25
Authors: Wu, Y., Qi, J.X., Gao, F., Gao, G.F.
PDB entry 4mwr: Anhui N9-zanamivir
Classification: HYDROLASE
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.797 Å
Deposited: 2013-09-25
Authors: Wu, Y., Qi, J.X., Gao, F., Gao, G.F.
PDB entry 4mws: Crystal structure of human PPCA (trigonal crystal form 1)
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2013-09-25
Authors: Kolli, N., Garman, S.C.
PDB entry 4mwt: Crystal structure of human PPCA (trigonal crystal form 2)
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.85 Å
Deposited: 2013-09-25
Authors: Kolli, N., Garman, S.C.
PDB entry 4mwu: Anhui N9-laninamivir
Classification: HYDROLASE
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.799 Å
Deposited: 2013-09-25
Authors: Wu, Y., Qi, J.X., Gao, F., Gao, G.F.
PDB entry 4mwv: Anhui N9-peramivir
Classification: HYDROLASE
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2013-09-25
Authors: Wu, Y., Qi, J.X., Gao, F., Gao, G.F.
PDB entry 4mww: Shanghai N9-oseltamivir carboxylate
Classification: HYDROLASE
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2013-09-25
Authors: Wu, Y., Qi, J.X., Gao, F., Gao, G.F.
PDB entry 4mwx: Shanghai N9-zanamivir
Classification: HYDROLASE
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.801 Å
Deposited: 2013-09-25
Authors: Wu, Y., Qi, J.X., Gao, F., Gao, G.F.
PDB entry 4mwy: Shanghai N9-laninamivir
Classification: HYDROLASE
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-09-25
Authors: Wu, Y., Qi, J.X., Gao, F., Gao, G.F.
PDB entry 4mwz: Crystal structure of N-methyl transferase from Plasmodium vivax complexed with S-adenosyl methionine, phosphate and amodiaquine
Classification: transferase/transferase inhibitor
Source organism: Plasmodium vivax
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2013-09-25
Authors: Lukk, T., Nair, S.K.
PDB entry 4mx0: Shanghai N9-peramivir
Classification: HYDROLASE
Source organism: Influenza A virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.101 Å
Deposited: 2013-09-25
Authors: Wu, Y., Qi, J.X., Gao, F., Gao, G.F.
PDB entry 4mx1: Structure of ricin A chain bound with 2-amino-4-oxo-N-(2-(3-phenylureido)ethyl)-3,4-dihydropteridine-7-carboxamide
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Ricinus communis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.59 Å
Deposited: 2013-09-25
Authors: Robertus, J.D., Wiget, P.A., Manzano, L.A., Pruet, J.M., Gao, G., Saito, R., Jasheway, K.R., Monzingo, A.F., Anslyn, E.V.
PDB entry 4mx2: Crystal Structure of adenylosuccinate lyase from Leishmania donovani
Classification: LYASE
Source organism: Leishmania donovani
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2013-09-25
Authors: Wernimont, A.K., Loppnau, P., Dong, A., Krojer, T., Bradley, A., Bushell, S., von Delft, F., Robinson, D., Gilbert, I., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Hui, R., Mottaghi, K., Structural Genomics Consortium (SGC)
PDB entry 4mx3: Crystal Structure of PKA RIalpha Homodimer
Classification: SIGNALING PROTEIN
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.88 Å
Deposited: 2013-09-25
Authors: Bruystens, J.G.H., Wu, J., Fortezzo, A., Kornev, A.P., Blumenthal, D.A., Taylor, S.S.
PDB entry 4mx5: Structure of ricin A chain bound with benzyl-(2-(2-amino-4-oxo-3,4-dihydropteridine-7-carboxamido)ethyl)carbamate
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Ricinus communis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.52 Å
Deposited: 2013-09-25
Authors: Jasheway, K.R., Robertus, J.D., Wiget, P.A., Manzano, L.A., Pruet, J.M., Gao, G., Saito, R., Monzingo, A.F., Anslyn, E.V.
PDB entry 4mx6: Crystal structure of a trap periplasmic solute binding protein from shewanella oneidensis (SO_3134), target EFI-510275, with bound succinate
Classification: TRANSPORT PROTEIN
Source organism: Shewanella oneidensis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.1 Å
Deposited: 2013-09-25
Authors: Vetting, M.W., Toro, R., Bhosle, R., Al Obaidi, N.F., Morisco, L.L., Wasserman, S.R., Sojitra, S., Zhao, S., Stead, M., Attonito, J.D., Scott Glenn, A., Chowdhury, S., Evans, B., Hillerich, B., Love, J., Seidel, R.D., Imker, H.J., Jacobson, M.P., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4mx7: Structure of mouse CD1d in complex with dioleoyl-phosphatidic acid
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.24 Å
Deposited: 2013-09-25
Authors: Zajonc, D.M., Wang, J.
PDB entry 4mx8: Crystal Structure of TroA-like Periplasmic Binding Protein Peripla_BP_2 from Xylanimonas cellulosilytica
Classification: SOLUTE-BINDING PROTEIN
Source organism: Xylanimonas cellulosilytica
Experimental method: X-RAY DIFFRACTION
Resolution: 2.911 Å
Deposited: 2013-09-26
Authors: Kim, Y., Wu, R., Endres, M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 4mx9: CDPK1 from Neospora caninum in complex with inhibitor UW1294
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Neospora caninum
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1 Å
Deposited: 2013-09-26
Authors: Merritt, E.A.
PDB entry 4mxa: CDPK1 from Neospora caninum in complex with inhibitor RM-1-132
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Neospora caninum
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2013-09-26
Authors: Merritt, E.A.
PDB entry 4mxc: Crystal structure of CMET in complex with novel inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.632 Å
Deposited: 2013-09-26
Authors: Liu, Q.F., Chen, T.T., Xu, Y.C.
PDB entry 4mxd: 1.45 angstronm crystal structure of E.coli 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (MenH)
Classification: LYASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2013-09-26
Authors: Sun, Y., Yin, S., Feng, Y., Li, J., Zhou, J., Liu, C., Zhu, G., Guo, Z.
PDB entry 4mxe: Human ESCO1 (Eco1/Ctf7 ortholog), acetyltransferase domain in complex with acetyl-CoA
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2013-09-26
Authors: Karlberg, T., Wisniewska, M., Thorsell, A.G., Kouznetsova, E., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Kallas, A., Kraulis, P., Kotenyova, T., Moche, M., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Schutz, P., Svensson, L., Tresaugues, L., Van Den Berg, S., Wahlberg, E., Weigelt, J., Welin, M., Schuler, H., Structural Genomics Consortium (SGC)
PDB entry 4mxf: X-ray structure of the adduct between bovine pancreatic ribonuclease and Auoxo6, a dinuclear gold(III) complex with -dioxo bridges linking the two metal centers
Classification: HYDROLASE
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2013-09-26
Authors: Russo Krauss, I., Vergara, A., Merlino, A.
PDB entry 4mxi: ClpP Ser98dhA
Classification: HYDROLASE
Source organism: Staphylococcus aureus subsp. aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2013-09-26
Authors: Gersch, M., Kolb, R., Alte, F., Groll, M., Sieber, S.A.
PDB entry 4mxj: Thermolysin in complex with UBTLN35
Classification: hydrolase/hydrolase inhibitor
Source organism: Bacillus thermoproteolyticus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.349 Å
Deposited: 2013-09-26
Authors: Krimmer, S.G., Heine, A., Klebe, G.
PDB entry 4mxk: X-ray structure of Fe(II)-ZnPIXFeBMb1
Classification: OXYGEN TRANSPORT
Source organism: Physeter catodon
Experimental method: X-RAY DIFFRACTION
Resolution: 1.52 Å
Deposited: 2013-09-26
Authors: Chakraborty, S., Lu, Y., Petrik, I.
PDB entry 4mxl: X-ray structure of ZnPFeBMb1
Classification: OXYGEN TRANSPORT
Source organism: Physeter catodon
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2013-09-26
Authors: Chakraborty, S., Lu, Y., Petrik, I.
PDB entry 4mxm: Crystal structure of superantigen pfit
Classification: DNA BINDING PROTEIN
Source organism: Pseudomonas fluorescens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2013-09-26
Authors: Liu, L.H., Chen, H., Li, H.M.
PDB entry 4mxn: Crystal structure of a putative glycosyl hydrolase (PARMER_00599) from Parabacteroides merdae ATCC 43184 at 1.95 A resolution
Classification: HYDROLASE
Source organism: Parabacteroides merdae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2013-09-26
Authors: Joint Center for Structural Genomics (JCSG)
PDB entry 4mxo: human Src kinase bound to kinase inhibitor bosutinib
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.105 Å
Deposited: 2013-09-26
Authors: Levinson, N.M., Boxer, S.G.
PDB entry 4mxp: Structural Basis for PI(4)P-Specific Membrane Recruitment of the Legionella pneumophila Effector DrrA/SidM
Classification: PI(4)P-BINDING PROTEIN
Source organism: Legionella pneumophila subsp. pneumophila
Experimental method: X-RAY DIFFRACTION
Resolution: 1.83 Å
Deposited: 2013-09-26
Authors: Del Campo, C.M., Mishra, A.K., Wang, Y.H., Roy, C.R., Janmey, P.A., Lambright, D.G.
PDB entry 4mxq: 42F3 TCR pCPC5/H-2Ld Complex
Classification: IMMUNE SYSTEM
Source organism: Mus musculus; Mus musculus, Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.596 Å
Deposited: 2013-09-26
Authors: Birnbaum, M.E., Adams, J.J., Garcia, K.C.
PDB entry 4mxr: Crystal structure of Trypanosoma cruzi formiminoglutamase with Mn2+2
Classification: HYDROLASE
Source organism: Trypanosoma cruzi
Experimental method: X-RAY DIFFRACTION
Resolution: 1.849 Å
Deposited: 2013-09-26
Authors: Hai, Y., Dugery, R.-J., Healy, D., Christianson, D.W.
PDB entry 4mxt: Crystal structure of an Outer-membrane lipoprotein carrier protein (BACUNI_04723) from Bacteroides uniformis ATCC 8492 at 1.40 A resolution
Classification: PROTEIN TRANSPORT
Source organism: Bacteroides uniformis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2013-09-26
Authors: Joint Center for Structural Genomics (JCSG)
PDB entry 4mxu: Human brain aspartoacylase mutant K213E complex with intermediate analog (N-phosphonomethyl-L-aspartate)
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2013-09-26
Authors: Wijayasinghe, Y.S., Pavlovsky, A.G., Viola, R.E.
PDB entry 4mxv: Structure of Lymphotoxin alpha bound to anti-LTa Fab
Classification: CYTOKINE/IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2 Å
Deposited: 2013-09-26
Authors: Yin, J.P., Hymowitz, S.G.
PDB entry 4mxw: Structure of heterotrimeric lymphotoxin LTa1b2 bound to lymphotoxin beta receptor LTbR and anti-LTa Fab
Classification: CYTOKINE/IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.6 Å
Deposited: 2013-09-26
Authors: Sudhamsu, J., Yin, J.P., Hymowitz, S.G.
PDB entry 4mxx: Human Src A403T mutant bound to kinase inhibitor bosutinib
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2013-09-26
Authors: Levinson, N.M., Boxer, S.G.
PDB entry 4mxy: Src M314L T338M double mutant bound to kinase inhibitor bosutinib
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.582 Å
Deposited: 2013-09-26
Authors: Levinson, N.M., Boxer, S.G.
PDB entry 4mxz: Src M314L T338M double mutant bound to kinase inhibitor bosutinib
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.582 Å
Deposited: 2013-09-26
Authors: Levinson, N.M., Boxer, S.G.
PDB entry 4my0: Crystal Structure of GCN5-related N-acetyltransferase from Kribbella flavida
Classification: TRANSFERASE
Source organism: Kribbella flavida
Experimental method: X-RAY DIFFRACTION
Resolution: 2.101 Å
Deposited: 2013-09-26
Authors: Kim, Y., Mack, J., Endres, M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 4my1: Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Bacillus anthracis str. Ames complexed with P68
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Bacillus anthracis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5997 Å
Deposited: 2013-09-26
Authors: Kim, Y., Makowska-Grzyska, M., Gu, M., Gorla, S.K., Hedstrom, L., Anderson, W.F., Joachimiak, A., CSGID, Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4my2: Crystal Structure of Norrin in fusion with Maltose Binding Protein
Classification: SIGNALING PROTEIN
Source organism: Escherichia coli O157:H7; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2013-09-27
Authors: Ke, J., Jurecky, C., Chen, C., Gu, X., Parker, N., Williams, B.O., Melcher, K., Xu, H.E.
PDB entry 4my3: Crystal Structure of GCN5-related N-acetyltransferase from Kribbella flavida
Classification: TRANSFERASE
Source organism: Kribbella flavida
Experimental method: X-RAY DIFFRACTION
Resolution: 2.57 Å
Deposited: 2013-09-27
Authors: Kim, Y., Mack, J., Endres, M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 4my4: Crystal structure of phosphoglycerate mutase from Staphylococcus aureus.
Classification: ISOMERASE
Source organism: Staphylococcus aureus subsp. aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2013-09-27
Authors: Roychowdhury, A., Kundu, A., Gujar, A., Bose, M., Das, A.K.
PDB entry 4my5: Crystal structure of the aromatic amino acid aminotransferase from Streptococcus mutants
Classification: TRANSFERASE
Source organism: Streptococcus mutans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.194 Å
Deposited: 2013-09-27
Authors: Cong, X., Li, X., Ge, J., Feng, Y., Feng, X., Li, S.
PDB entry 4my6: EnaH-EVH1 in complex with peptidomimetic low-molecular weight inhibitor Ac-[2-Cl-F]-[ProM-2]-[ProM-1]-OH
Classification: Cell adhesion/inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2013-09-27
Authors: Barone, M., Roske, Y., Kuehne, R.
PDB entry 4my7: frog M ferritin iron-loaded under anaerobic environment
Classification: OXIDOREDUCTASE
Source organism: Rana catesbeiana
Experimental method: X-RAY DIFFRACTION
Resolution: 1.48 Å
Deposited: 2013-09-27
Authors: Mangani, S., Di Pisa, F., Pozzi, C., Turano, P., Lalli, D.
PDB entry 4my8: Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor Q21
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Bacillus anthracis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2924 Å
Deposited: 2013-09-27
Authors: Kim, Y., Makowska-Grzyska, M., Gu, M., Gorla, S.K., Kavitha, M., Cuny, G., Hedstrom, L., Anderson, W.F., Joachimiak, A., CSGID, Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4my9: Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor C91
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Bacillus anthracis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5893 Å
Deposited: 2013-09-27
Authors: Kim, Y., Makowska-Grzyska, M., Gu, M., Gorla, S.K., Hedstrom, L., Anderson, W.F., Joachimiak, A., CSGID, Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4mya: Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor A110
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Bacillus anthracis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8997 Å
Deposited: 2013-09-27
Authors: Kim, Y., Makowska-Grzyska, M., Gu, M., Gorla, S.K., Hedstrom, L., Anderson, W.F., Joachimiak, A., CSGID, Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4myb: Crystal Structure of Francisella tularensis 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD)
Classification: TRANSFERASE
Source organism: Francisella tularensis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2013-09-27
Authors: Noble, S.M., Tsang, A.K., Couch, R.D.
PDB entry 4myc: Structure of the mitochondrial ABC transporter, Atm1
Classification: TRANSPORT PROTEIN
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 3.06 Å
Deposited: 2013-09-27
Authors: Srinivasan, V.
PDB entry 4myd: 1.37 Angstrom Crystal Structure of E. Coli 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (MenH) in complex with SHCHC
Classification: LYASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.374 Å
Deposited: 2013-09-27
Authors: Sun, Y., Yin, S., Feng, Y., Li, J., Zhou, J., Liu, C., Zhu, G., Guo, Z.
PDB entry 4mye: Cymosema roseum seed lectin structure complexed with X-man
Classification: Carbohydrate-binding protein
Source organism: Cymbosema roseum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2013-09-27
Authors: Barroso-Neto, I.L., Rocha, B.A.M., Teixeira, C.S., Santiago, M.Q., Souza, L.A.G., Pires, A.F., Assreuy, A.M.S., Delatorre, P., Cavada, B.S.
PDB entry 4myf: Crystal structure of Trypanosoma cruzi formiminoglutamase(oxidized) with Mn2+2 at pH 6.0
Classification: HYDROLASE
Source organism: Trypanosoma cruzi
Experimental method: X-RAY DIFFRACTION
Resolution: 1.799 Å
Deposited: 2013-09-27
Authors: Hai, Y., Dugery, R.J., Healy, D., Christianson, D.W.
PDB entry 4myg: MAPK13, active form
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.594 Å
Deposited: 2013-09-27
Authors: Yurtsever, Z., Brett, T.J., Scheaffer, S.M.
PDB entry 4myh: Structure of the Glutathione bound mitochondrial ABC transporter, Atm1
Classification: TRANSPORT PROTEIN
Source organism: Saccharomyces cerevisiae
Experimental method: X-RAY DIFFRACTION
Resolution: 3.38 Å
Deposited: 2013-09-27
Authors: Srinivasan, V.
PDB entry 4myk: Crystal structure of Trypanosoma cruzi formiminoglutamase (oxidized) with Mn2+2 at pH 8.5
Classification: HYDROLASE
Source organism: Trypanosoma cruzi
Experimental method: X-RAY DIFFRACTION
Resolution: 1.518 Å
Deposited: 2013-09-27
Authors: Hai, Y., Dugery, R.J., Healy, D., Christianson, D.W.
PDB entry 4myl: Crystal structure of Trypanosoma cruzi Formiminoglutamase (oxidized) at pH 4.6
Classification: HYDROLASE
Source organism: Trypanosoma cruzi
Experimental method: X-RAY DIFFRACTION
Resolution: 1.531 Å
Deposited: 2013-09-27
Authors: Hai, Y., Dugery, R.J., Healy, D., Christianson, D.W.
PDB entry 4mym: Crystal structure of a glyoxalase/ bleomycin resistance protein/ dioxygenase from Nocardioides
Classification: OXIDOREDUCTASE
Source organism: Nocardioides sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2013-09-27
Authors: Eswaramoorthy, S., Chamala, S., Evans, B., Foti, F., Gizzi, A., Hillerich, B., Kar, A., Lafleur, J., Seidel, R., Villigas, G., Zencheck, W., AL Obaidi, N., Almo, S.C., Swaminathan, S., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4myn: Crystal structure of Trypanosoma cruzi formiminoglutamase N114H variant with Mn2+2
Classification: HYDROLASE
Source organism: Trypanosoma cruzi
Experimental method: X-RAY DIFFRACTION
Resolution: 1.799 Å
Deposited: 2013-09-27
Authors: Hai, Y., Dugery, R.J., Healy, D., Christianson, D.W.
PDB entry 4myo: Crystal structure of streptogramin group A antibiotic acetyltransferase VatA from Staphylococcus aureus
Classification: TRANSFERASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.696 Å
Deposited: 2013-09-27
Authors: Stogios, P.J., Minasov, G., Dong, A., Evdokimova, E., Yim, V., Krishnamoorthy, M., Di Leo, R., Courvalin, P., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4myp: Structure of the central NEAT domain, N2, of the listerial Hbp2 protein complexed with heme
Classification: HEME-BINDING PROTEIN
Source organism: Listeria monocytogenes
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-09-27
Authors: Malmirchegini, G.R., Sawaya, M.R., Clubb, R.T.
PDB entry 4myq: Selective Inhibition of the Catalytic Domain Of Human Phosphodiesterase 4B With A-33
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2013-09-27
Authors: Fox III, D., Edwards, T.E.
PDB entry 4myr: Crystal structure of a putative CpaE2 pilus assembly protein (CpaE2) from Sinorhizobium meliloti 1021 at 2.72 A resolution (PSI Community Target, Shapiro)
Classification: TRANSCRIPTION
Source organism: Sinorhizobium meliloti
Experimental method: X-RAY DIFFRACTION
Resolution: 2.72 Å
Deposited: 2013-09-27
Authors: Joint Center for Structural Genomics (JCSG)
PDB entry 4mys: 1.4 Angstrom Crystal Structure of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase with SHCHC and Pyruvate
Classification: LYASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.423 Å
Deposited: 2013-09-28
Authors: Sun, Y., Yin, S., Feng, Y., Li, J., Zhou, J., Liu, C., Zhu, G., Guo, Z.
PDB entry 4myt: Crystal structure of elongation factor G (EFG)
Classification: TRANSLATION
Source organism: Thermus thermophilus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.505 Å
Deposited: 2013-09-28
Authors: Liu, G., Dong, J., Gong, W., Qin, Y.
PDB entry 4myu: Crystal structure of elongation factor G mutant(EFG)
Classification: TRANSLATION
Source organism: Thermus thermophilus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.004 Å
Deposited: 2013-09-28
Authors: Liu, G., Dong, J., Gong, W., Qin, Y.
PDB entry 4myv: Free HSV-2 gD structure
Classification: VIRAL PROTEIN
Source organism: Human herpesvirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 1.801 Å
Deposited: 2013-09-28
Authors: Lu, G., Zhang, N., Qi, J., Li, Y., Chen, Z., Zheng, C., Yan, J., Gao, G.F.
PDB entry 4myw: Structure of HSV-2 gD bound to nectin-1
Classification: VIRAL PROTEIN/CELL ADHESION
Source organism: Homo sapiens; Human herpesvirus 2
Experimental method: X-RAY DIFFRACTION
Resolution: 3.189 Å
Deposited: 2013-09-28
Authors: Lu, G., Zhang, N., Qi, J., Li, Y., Chen, Z., Zheng, C., Yan, J., Gao, G.F.
PDB entry 4myx: Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Bacillus anthracis str. Ame complexed with P32
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Bacillus anthracis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.701 Å
Deposited: 2013-09-28
Authors: Kim, Y., Makowska-Grzyska, M., Gu, M., Gorla, S.K., Hedstrom, L., Anderson, W.F., Joachimiak, A., CSGID, Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4myy: Structure of a class 2 docking domain complex from modules CurG and CurH of the curacin A polyketide synthase
Classification: PROTEIN BINDING
Source organism: Moorea producens 3L
Experimental method: X-RAY DIFFRACTION
Resolution: 1.68 Å
Deposited: 2013-09-28
Authors: Whicher, J.R., Smaga, S.S., Smith, J.L.
PDB entry 4myz: Structure of a class 2 docking domain complex from modules CurK and CurL of the curacin A polyketide synthase
Classification: PROTEIN BINDING
Source organism: Moorea producens 3L
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2013-09-28
Authors: Whicher, J.R., Smaga, S.S., Smith, J.L.
PDB entry 4mz0: Structure of a ketosynthase-acyltransferase di-domain from module CurL of the curacin A polyketide synthase
Classification: TRANSFERASE
Source organism: Moorea producens 3L
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2013-09-28
Authors: Whicher, J.R., Smaga, S.S., Smith, J.L.
PDB entry 4mz1: Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound P12
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Campylobacter jejuni subsp. jejuni
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3991 Å
Deposited: 2013-09-28
Authors: Kim, Y., Makowska-Grzyska, M., Gu, M., Anderson, W.F., Joachimiak, A., CSGID, Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4mz2: Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.722 Å
Deposited: 2013-09-28
Authors: Das, S., Van Petegem, F.
PDB entry 4mz3: Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain, C131W mutant
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.741 Å
Deposited: 2013-09-28
Authors: Das, S., Van Petegem, F.
PDB entry 4mz4: Discovery of an Irreversible HCV NS5B Polymerase Inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Hepatitis C virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.63 Å
Deposited: 2013-09-29
Authors: Zeng, Q., Anilkumar, G.N., Rosenblum, S.B., Huang, H.-C., Lesburg, C.A., Jiang, Y., Selyutin, O., Chan, T.-Y., Bennett, F., Chen, K.X., Venkatraman, S., Sannigrahi, M., Velazquez, F., Duca, J.S., Gavalas, S., Huang, Y., Pu, H., Wang, L., Pinto, P., Vibulbhan, B., Agrawal, S., Ferrari, E., Jiang, C.-K., Li, C., Hesk, D., Gesell, J., Sorota, S., Shih, N.-Y., Njoroge, F.G., Kozlowski, J.A.
PDB entry 4mz5: Structure of importin-alpha: dUTPase NLS complex
Classification: PROTEIN TRANSPORT
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2013-09-29
Authors: Marfori, M., Rona, G., Vertessy, B.G., Kobe, B.
PDB entry 4mz6: Structure of importin-alpha: dUTPase S11E NLS mutant complex
Classification: PROTEIN TRANSPORT
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.88 Å
Deposited: 2013-09-29
Authors: Marfori, M., Rona, G., Vertessy, B.G., Kobe, B.
PDB entry 4mz7: Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-09-29
Authors: Zhu, C., Gao, W., Zhao, K., Qin, X., Zhang, Y., Peng, X., Zhang, L., Dong, Y., Zhang, W., Li, P., Wei, W., Gong, Y., Yu, X.F.
PDB entry 4mz8: Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with an Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound C91
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Campylobacter jejuni subsp. jejuni
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5004 Å
Deposited: 2013-09-29
Authors: Kim, Y., Makowska-Grzyska, M., Gu, M., Gorla, S.K., Hedstrom, L., Anderson, W.F., Joachimiak, A., CSGID, Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4mz9: Revised structure of E. coli SSB
Classification: DNA BINDING PROTEIN
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2013-09-29
Authors: Oakley, A.J.
PDB entry 4mza: Crystal structure of hPIV3 hemagglutinin-neuraminidase
Classification: HYDROLASE
Source organism: Human parainfluenza 3 virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.653 Å
Deposited: 2013-09-29
Authors: Xu, R., Wilson, I.A.
PDB entry 4mzb: Crystal structure of Grx1 from Plasmodium falciparum
Classification: OXIDOREDUCTASE
Source organism: Plasmodium falciparum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.038 Å
Deposited: 2013-09-30
Authors: Yogavel, M., Sharma, A.
PDB entry 4mzc: Atomic Resolution Structure of PfGrx1
Classification: OXIDOREDUCTASE
Source organism: Plasmodium falciparum
Experimental method: X-RAY DIFFRACTION
Resolution: 0.949 Å
Deposited: 2013-09-30
Authors: Yogavel, M., Sharma, A.
PDB entry 4mzd: High resolution crystal structure of the nisin leader peptidase NisP from Lactococcus lactis
Classification: HYDROLASE
Source organism: Lactococcus lactis subsp. lactis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.1 Å
Deposited: 2013-09-30
Authors: Rao, Z.H., Xu, Y.Y., Li, X., Yang, W.
PDB entry 4mze: Crystal structure of hPIV3 hemagglutinin-neuraminidase, H552Q/Q559R mutant
Classification: HYDROLASE
Source organism: Human parainfluenza 3 virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-09-30
Authors: Xu, R., Wilson, I.A.
PDB entry 4mzf: Crystal structure of human Spindlin1 bound to histone H3(K4me3-R8me2a) peptide
Classification: GENE REGULATION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.098 Å
Deposited: 2013-09-30
Authors: Su, X., Ding, X., Li, H.
PDB entry 4mzg: Crystal structure of human Spindlin1 bound to histone H3K4me3 peptide
Classification: GENE REGULATION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.698 Å
Deposited: 2013-09-30
Authors: Su, X., Ding, X., Li, H.
PDB entry 4mzh: Crystal structure of human Spindlin1 bound to histone H3(K4me3-R8me2s) peptide
Classification: GENE REGULATION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.204 Å
Deposited: 2013-09-30
Authors: Su, X., Ding, X., Li, H.
PDB entry 4mzi: Crystal structure of a human mutant p53
Classification: ANTITUMOR PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.25 Å
Deposited: 2013-09-30
Authors: Emamzadah, S., Tropia, L., Vincenti, I., Falquet, B., Halazonetis, T.D.
PDB entry 4mzj: Crystal Structure of MTIP from Plasmodium falciparum in complex with pGly[801,805], a stapled myoA tail peptide
Classification: PROTEIN BINDING/inhibitor
Source organism: Plasmodium falciparum; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.474 Å
Deposited: 2013-09-30
Authors: Douse, C.H., Garnett, J.A., Maas, S.J., Cota, E., Tate, E.W.
PDB entry 4mzk: Crystal Structure of MTIP from Plasmodium falciparum in complex with pGly[807,811], a stapled myoA tail peptide
Classification: PROTEIN BINDING/inhibitor
Source organism: Plasmodium falciparum; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.82 Å
Deposited: 2013-09-30
Authors: Douse, C.H., Garnett, J.A., Maas, S.J., Cota, E., Tate, E.W.
PDB entry 4mzl: Crystal Structure of MTIP from Plasmodium falciparum in complex with HBS myoA, a hydrogen bond surrogate myoA helix mimetic
Classification: PROTEIN BINDING/INHIBITOR
Source organism: Plasmodium falciparum 3D7; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.01 Å
Deposited: 2013-09-30
Authors: Douse, C.H., Garnett, J.A., Maas, S.J., Cota, E., Tate, E.W.
PDB entry 4mzm: MazF from S. aureus crystal form I, P212121, 2.1 A
Classification: HYDROLASE
Source organism: Staphylococcus aureus subsp. aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2013-09-30
Authors: Zorzini, V., Loris, R., van Nuland, N.A.J., Cheung, A.
PDB entry 4mzn: Thermolysin in complex with UBTLN59
Classification: hydrolase/hydrolase inhibitor
Source organism: Bacillus thermoproteolyticus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.172 Å
Deposited: 2013-09-30
Authors: Krimmer, S.G., Heine, A., Klebe, G.
PDB entry 4mzo: Mouse cathepsin s with covalent ligand (3S,4S)-N-[(2E)-2-IMINOETHYL]-4-(MORPHOLIN-4-YLCARBONYL)-1-(PHENYLSULFONYL)PYRROLIDINE-3-CARBOXAMIDE
Classification: hydrolase/hydrolase inhibitor
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.47 Å
Deposited: 2013-09-30
Authors: Kuglstatter, A., Stihle, M.
PDB entry 4mzp: MazF from S. aureus crystal form III, C2221, 2.7 A
Classification: HYDROLASE
Source organism: Staphylococcus aureus subsp. aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.702 Å
Deposited: 2013-09-30
Authors: Zorzini, V., Loris, R., van Nuland, N.A.J., Cheung, A.
PDB entry 4mzq: beta-Alanyl-CoA:Ammonia Lyase from Clostridium propionicum in complex with propionyl-CoA
Classification: LYASE
Source organism: Clostridium propionicum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.587 Å
Deposited: 2013-09-30
Authors: Heine, A., Reuter, K.
PDB entry 4mzr: Crystal structure of a polypeptide p53 mutant bound to DNA
Classification: TRANSCRIPTION/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2013-09-30
Authors: Emamzadah, S.T., Tropia, L., Vincenti, I., Falquet, B., Halazonetis, T.D.
PDB entry 4mzs: Mouse cathepsin s with covalent ligand (3S,4S)-1-[(2-CHLOROPHENYL)SULFONYL]-N-[(2E)-2-IMINOETHYL]-4-(MORPHOLIN-4-YLCARBONYL)PYRROLIDINE-3-CARBOXAMIDE
Classification: hydrolase/hydrolase inhibitor
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2013-09-30
Authors: Kuglstatter, A., Stihle, M.
PDB entry 4mzt: MazF from S. aureus crystal form II, C2221, 2.3 A
Classification: HYDROLASE
Source organism: Staphylococcus aureus subsp. aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.303 Å
Deposited: 2013-09-30
Authors: Zorzini, V., Loris, R., van Nuland, N.A.J., Cheung, A.
PDB entry 4mzu: Crystal structure of FdtD, a bifunctional ketoisomerase/N-acetyltransferase from Shewanella denitrificans
Classification: ISOMERASE, TRANSFERASE
Source organism: Shewanella denitrificans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2013-09-30
Authors: Chantigian, D.P., Thoden, J.B., Holden, H.M.
PDB entry 4mzv: Crystal structure of extracellular part of human EpCAM
Classification: CELL ADHESION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.865 Å
Deposited: 2013-09-30
Authors: Pavsic, M., Guncar, G., Djinovic-Carugo, K., Lenarcic, B.
PDB entry 4mzw: CRYSTAL STRUCTURE OF NU-CLASS GLUTATHIONE TRANSFERASE YGHU FROM Streptococcus sanguinis SK36, COMPLEX WITH GLUTATHIONE DISULFIDE, TARGET EFI-507286
Classification: TRANSFERASE
Source organism: Streptococcus sanguinis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2013-09-30
Authors: Patskovsky, Y., Toro, R., Bhosle, R., Hillerich, B., Seidel, R.D., Washington, E., Scott Glenn, A., Chowdhury, S., Evans, B., Hammonds, J., Imker, H.J., Al Obaidi, N., Stead, M., Love, J., Gerlt, J.A., Armstrong, R.N., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4mzx: Crystal Structure of Benzoylformate Decarboxylase Mutant T377L/A460Y
Classification: LYASE
Source organism: Pseudomonas putida
Experimental method: X-RAY DIFFRACTION
Resolution: 1.558 Å
Deposited: 2013-09-30
Authors: Andrews, F.H., McLeish, M.J.
PDB entry 4mzy: Crystal structure of enterococcus faecalis nicotinate phosphoribosyltransferase with malonate and phosphate bound
Classification: TRANSFERASE
Source organism: ENTEROCOCCUS FAECALIS
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2013-09-30
Authors: Patskovsky, Y., Toro, R., Wasserman, S.R., Almo, S.C., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC), New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4mzz: Crystal structure of Bovine 3 Glu-Osteocalcin.
Classification: STRUCTURAL PROTEIN
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.88 Å
Deposited: 2013-09-30
Authors: Malashkevich, V.N., Dowd, T.L., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4n00: Discovery of 7-THP chromans: BACE1 inhibitors that reduce A-beta in the CNS
Classification: hydrolase/hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-09-30
Authors: Vigers, G.P.A., Smith, D.
PDB entry 4n01: The crystal structure of a periplasmic binding protein from Veillonella parvula dsm 2008
Classification: TRANSPORT PROTEIN
Source organism: Veillonella parvula
Experimental method: X-RAY DIFFRACTION
Resolution: 1.797 Å
Deposited: 2013-09-30
Authors: Wu, R., Endres, M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 4n02: Type 2 IDI from S. pneumoniae
Classification: ISOMERASE
Source organism: Streptococcus pneumoniae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2013-09-30
Authors: de Ruyck, J., Schubert, H.L., Poulter, C.D.