LiteFold/PDB huggingface dataset:
PDB entry 4k8p: Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 2-ethylbenzyl alcohol
Classification: TRANSFERASE
Source organism: Rhizobium etli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2013-04-18
Authors: Malashkevich, V.N., Bhosle, R., Toro, R., Hillerich, B., Gizzi, A., Garforth, S., Kar, A., Chan, M.K., Lafluer, J., Patel, H., Matikainen, B., Chamala, S., Lim, S., Celikgil, A., Villegas, G., Evans, B., Love, J., Fiser, A., Khafizov, K., Seidel, R., Bonanno, J.B., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4k8r: An Antibody Against the C-terminal Domain of PCSK9 lowers LDL Cholesterol Levels in vivo
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.22 Å
Deposited: 2013-04-18
Authors: Schiele, F., Nar, H.
PDB entry 4k8s: Hydroxyethylamine-based inhibitors of BACE1: P1-P3 macrocyclization can improve potency, selectivity, and cell activity
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.39 Å
Deposited: 2013-04-18
Authors: Jordan, S.R.
PDB entry 4k8t: Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with ethyl 3,4-diaminobenzoate
Classification: TRANSFERASE
Source organism: Rhizobium etli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2013-04-18
Authors: Malashkevich, V.N., Bhosle, R., Toro, R., Hillerich, B., Gizzi, A., Garforth, S., Kar, A., Chan, M.K., Lafluer, J., Patel, H., Matikainen, B., Chamala, S., Lim, S., Celikgil, A., Villegas, G., Evans, B., Love, J., Fiser, A., Khafizov, K., Seidel, R., Bonanno, J.B., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4k8u: Crystal structure of TRAF4 TRAF domain
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.302 Å
Deposited: 2013-04-18
Authors: Park, H.H., Yoon, J.H.
PDB entry 4k8v: Structure of cyclic GMP-AMP Synthase (cGAS)
Classification: TRANSFERASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2013-04-18
Authors: Gao, P., Wu, Y., Patel, D.J.
PDB entry 4k8w: An arm-swapped dimer of the S. pyogenes pilin specific assembly factor SipA
Classification: CELL ADHESION
Source organism: Streptococcus pyogenes
Experimental method: X-RAY DIFFRACTION
Resolution: 1.67 Å
Deposited: 2013-04-19
Authors: Young, P.G., Kang, H.J., Baker, E.N.
PDB entry 4k8x: Binary complex of 9N DNA polymerase in the replicative state
Classification: TRANSFERASE/DNA
Source organism: Thermococcus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.28 Å
Deposited: 2013-04-19
Authors: Betz, K., Diederichs, K., Marx, A.
PDB entry 4k8y: Atomic resolution crystal structures of Kallikrein-Related Peptidase 4 complexed with Sunflower Trypsin Inhibitor (SFTI-1)
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1 Å
Deposited: 2013-04-19
Authors: Ilyichova, O.V., Swedberg, J.E., de Veer, S.J., Sit, K.C., Harris, J.M., Buckle, A.M.
PDB entry 4k8z: KOD Polymerase in binary complex with dsDNA
Classification: TRANSFERASE/DNA
Source organism: Thermococcus kodakarensis; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.29 Å
Deposited: 2013-04-19
Authors: Bergen, K., Betz, K., Welte, W., Diederichs, K., Marx, A.
PDB entry 4k90: Extracellular metalloproteinase from Aspergillus
Classification: HYDROLASE
Source organism: Aspergillus fumigatus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-04-19
Authors: Fernandez, D., Russi, S., Vendrell, J., Monod, M., Pallares, I.
PDB entry 4k91: Crystal structure of Penicillin-Binding Protein 5 (PBP5) from Pseudomonas aeruginosa in apo state
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa UCBPP-PA14
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2013-04-19
Authors: Smith, J., Toth, M., Vakulenko, S., Mobashery, S., Chen, Y.
PDB entry 4k92: A Cryptic TOG Domain with a Distinct Architecture Underlies CLASP-Dependent Bipolar Spindle Formation
Classification: STRUCTURAL PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.005 Å
Deposited: 2013-04-19
Authors: Leano, J.B., Rogers, S.L., Slep, K.C.
PDB entry 4k93: CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42 complexed with N-(HYDROXYMETHYL)BENZAMIDE
Classification: TRANSFERASE
Source organism: Rhizobium etli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2013-04-19
Authors: Malashkevich, V.N., Bhosle, R., Toro, R., Hillerich, B., Gizzi, A., Garforth, S., Kar, A., Chan, M.K., Lafluer, J., Patel, H., Matikainen, B., Chamala, S., Lim, S., Celikgil, A., Villegas, G., Evans, B., Love, J., Fiser, A., Khafizov, K., Seidel, R., Bonanno, J.B., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4k94: Crystal structure of KIT D4D5 fragment in complex with anti-Kit antibody Fab19
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2013-04-19
Authors: Resheynyak, A.V., Boggon, T.J., Lax, I., Schlessinger, J.
PDB entry 4k95: Crystal Structure of Parkin
Classification: LIGASE
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 6.499 Å
Deposited: 2013-04-19
Authors: Seirafi, M., Menade, M., Sauve, V., Kozlov, G., Trempe, J.-F., Nagar, B., Gehring, K.
PDB entry 4k96: Structure of Binary Complex of cGAS with Bound dsDNA
Classification: TRANSFERASE/DNA
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.084 Å
Deposited: 2013-04-19
Authors: Gao, P., Wu, Y., Patel, D.J.
PDB entry 4k97: Structure of Ternary Complex of cGAS with dsDNA and Bound ATP
Classification: TRANSFERASE/DNA
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.41 Å
Deposited: 2013-04-19
Authors: Gao, P., Wu, Y., Patel, D.J.
PDB entry 4k98: Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG
Classification: TRANSFERASE/DNA
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.94 Å
Deposited: 2013-04-19
Authors: Gao, P., Wu, Y., Patel, D.J.
PDB entry 4k99: Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppdG(2 ,5 )pdG
Classification: TRANSFERASE/DNA
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2013-04-19
Authors: Gao, P., Wu, Y., Patel, D.J.
PDB entry 4k9a: Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pG(2 ,5 )pA
Classification: TRANSFERASE/DNA
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.264 Å
Deposited: 2013-04-19
Authors: Gao, P., Wu, Y., Patel, D.J.
PDB entry 4k9b: Structure of Ternary Complex of cGAS with dsDNA and Bound c[G(2 ,5 )pA(3 ,5 )p]
Classification: TRANSFERASE/DNA
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.26 Å
Deposited: 2013-04-19
Authors: Gao, P., Wu, Y., Patel, D.J.
PDB entry 4k9c: CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42 complexed with N-(HYDROXYMETHYL)BENZAMIDE and 4-METHYL-3,4-DIHYDRO-2H-1,4-BENZOXAZINE-7-CARBOXYLIC ACID
Classification: TRANSFERASE
Source organism: Rhizobium etli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2013-04-19
Authors: Malashkevich, V.N., Bhosle, R., Toro, R., Hillerich, B., Gizzi, A., Garforth, S., Kar, A., Chan, M.K., Lafluer, J., Patel, H., Matikainen, B., Chamala, S., Lim, S., Celikgil, A., Villegas, G., Evans, B., Love, J., Fiser, A., Khafizov, K., Seidel, R., Bonanno, J.B., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4k9d: X-ray crystal structure of a Glyceraldehyde 3-phosphate dehydrogenase from Brugia malayi bound to the co-factor NAD
Classification: OXIDOREDUCTASE
Source organism: Brugia malayi
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2013-04-19
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 4k9e: Crystal structure of KIT D4D5 fragment in complex with anti-Kit antibodies Fab79D
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2013-04-19
Authors: Resheynyak, A.V., Boggon, T.J., Lax, I., Schlessinger, J.
PDB entry 4k9f: Neutron structure of Perdeuterated Rubredoxin refined against 1.75 resolution data collected on the new IMAGINE instrument at HFIR, ORNL
Classification: ELECTRON TRANSPORT
Source organism: Pyrococcus furiosus
Experimental method: NEUTRON DIFFRACTION
Resolution: 1.75 Å
Deposited: 2013-04-19
Authors: Munshi, P., Meilleur, F., Myles, D.
PDB entry 4k9g: 1.55 A Crystal Structure of Macrophage Migration Inhibitory Factor bound to ISO-66 and a related compound
Classification: ISOMERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.55 Å
Deposited: 2013-04-19
Authors: Crichlow, G.V., Al-Abed, Y., Lolis, E.J.
PDB entry 4k9h: Bace-1 inhibitor complex
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.29 Å
Deposited: 2013-04-19
Authors: Jordan, S.R.
PDB entry 4k9i: CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42 complexed with Norharmane
Classification: TRANSFERASE
Source organism: Rhizobium etli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2013-04-19
Authors: Malashkevich, V.N., Bhosle, R., Toro, R., Hillerich, B., Gizzi, A., Garforth, S., Kar, A., Chan, M.K., Lafluer, J., Patel, H., Matikainen, B., Chamala, S., Lim, S., Celikgil, A., Villegas, G., Evans, B., Love, J., Fiser, A., Khafizov, K., Seidel, R., Bonanno, J.B., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4k9j: Structure of Re(CO)3(4,7-dimethyl-phen)(Thr126His)(Lys122Trp)(His83Glu)(Trp48Phe)(Tyr72Phe)(Tyr108Phe)AzCu(II), a Rhenium modified Azurin mutant
Classification: ELECTRON TRANSPORT
Source organism: Pseudomonas aeruginosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2013-04-20
Authors: Takematsu, K., Williamson, H.R., Blanco-Rodriguez, A.M., Sokolova, L., Nikolovski, P., Kaiser, J.T., Towrie, M., Clark, I.P., Vlcek Jr, A., Winkler, J.R., Gray, H.B.
PDB entry 4k9k: Crystal Structure of the His281Tyr mutant of Benzoylformate Decarboxylase from Pseudomonas putida
Classification: LYASE
Source organism: Pseudomonas putida
Experimental method: X-RAY DIFFRACTION
Resolution: 1.301 Å
Deposited: 2013-04-20
Authors: Brodkin, H.R., McLeish, M.J.
PDB entry 4k9l: Crystal Structure of the His281Thr mutant of Benzoylformate Decarboxylase from Pseudomonas putida
Classification: LYASE
Source organism: Pseudomonas putida
Experimental method: X-RAY DIFFRACTION
Resolution: 1.649 Å
Deposited: 2013-04-20
Authors: Brodkin, H.R., McLeish, M.J.
PDB entry 4k9m: Crystal Structure of the His281Asn mutant of Benzoylformate Decarboxylase from Pseudomonas putida
Classification: LYASE
Source organism: Pseudomonas putida
Experimental method: X-RAY DIFFRACTION
Resolution: 1.15 Å
Deposited: 2013-04-20
Authors: Brodkin, H.R., McLeish, M.J.
PDB entry 4k9n: Crystal Structure of the Ala460Ile mutant of Benzoylformate Decarboxylase from Pseudomonas putida
Classification: LYASE
Source organism: Pseudomonas putida
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2013-04-20
Authors: Brodkin, H.R., McLeish, M.J.
PDB entry 4k9o: Crystal Structure of the Phe397Ala mutant of Benzoylformate Decarboxylase from Pseudomonas putida
Classification: LYASE
Source organism: Pseudomonas putida
Experimental method: X-RAY DIFFRACTION
Resolution: 1.888 Å
Deposited: 2013-04-20
Authors: Brodkin, H.R., McLeish, M.J.
PDB entry 4k9p: Crystal Structure of the His281Tyr/Ala460Ile Double Mutant of Benzoylformate Decarboxylase from Pseudomonas putida
Classification: LYASE
Source organism: Pseudomonas putida
Experimental method: X-RAY DIFFRACTION
Resolution: 2.244 Å
Deposited: 2013-04-20
Authors: Brodkin, H.R., McLeish, M.J.
PDB entry 4k9q: The Crystal Structure of Benzoylformate Decarboxylase from Polynucleobacter necessarius
Classification: LYASE
Source organism: Polynucleobacter necessarius
Experimental method: X-RAY DIFFRACTION
Resolution: 1.598 Å
Deposited: 2013-04-20
Authors: Brodkin, H.R., Novak, W.R.P., McLeish, M.J.
PDB entry 4k9r: Spore photoproduct lyase Y98F mutant
Classification: LYASE
Source organism: Geobacillus thermodenitrificans
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2013-04-20
Authors: Yang, L., Nelson, R.S., Benjdia, A., Lin, G., Telser, J., Stoll, S., Schlichting, I., Li, L.
PDB entry 4k9s: Peptidoglycan O-acetylesterase in action, setmet
Classification: HYDROLASE
Source organism: Neisseria meningitidis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.334 Å
Deposited: 2013-04-21
Authors: Williams, A.H., Gompert Boneca, I.
PDB entry 4k9t: Complex of CYP3A4 with a desoxyritonavir analog
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2013-04-21
Authors: Sevrioukova, I.F., Poulos, T.L.
PDB entry 4k9u: Complex of human CYP3A4 with a desoxyritonavir analog
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.85 Å
Deposited: 2013-04-21
Authors: Sevrioukova, I.F., Poulos, T.L.
PDB entry 4k9v: Complex of CYP3A4 with a desoxyritonavir analog
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2013-04-21
Authors: Sevrioukova, I.F., Poulos, T.L.
PDB entry 4k9w: Complex of human CYP3A4 with a desoxyritonavir analog
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.399 Å
Deposited: 2013-04-21
Authors: Sevrioukova, I.F., Poulos, T.L.
PDB entry 4k9x: Complex of human CYP3A4 with a desoxyritonavir analog
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.76 Å
Deposited: 2013-04-21
Authors: Sevrioukova, I.F., Poulos, T.L.
PDB entry 4k9y: FOCAL ADHESION KINASE Catalytic domain in complex with 1-[4-(6-Amino-purin-9-yl)-phenyl]-3-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-urea
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2013-04-21
Authors: Musil, D., Graedler, U., Lehmann, M., Heinrich, T., Dresing, V.
PDB entry 4k9z: Crystal structure of a putative thiol-disulfide oxidoreductase from Bacteroides vulgatus (target NYSGRC-011676), space group P6222
Classification: OXIDOREDUCTASE
Source organism: Bacteroides vulgatus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-04-21
Authors: Vetting, M.W., Patskovsky, Y., Toro, R., Bhosle, R., Hillerich, B., Gizzi, A., Garforth, S., Kar, A., Chan, M.K., Lafluer, J., Patel, H., Matikainen, B., Chamala, S., Lim, S., Celikgil, A., Villegas, G., Evans, B., Love, J., Fiser, A., Khafizov, K., Seidel, R.D., Bonanno, J.B., Armstrong, R.N., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4ka0: Crystal structure of a putative thiol-disulfide oxidoreductase from Bacteroides vulgatus (target NYSGRC-011676), space group P21221
Classification: OXIDOREDUCTASE
Source organism: Bacteroides vulgatus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2013-04-21
Authors: Vetting, M.W., Patskovsky, Y., Toro, R., Bhosle, R., Hillerich, B., Gizzi, A., Garforth, S., Kar, A., Chan, M.K., Lafluer, J., Patel, H., Matikainen, B., Chamala, S., Lim, S., Celikgil, A., Villegas, G., Evans, B., Love, J., Fiser, A., Khafizov, K., Seidel, R.D., Bonanno, J.B., Armstrong, R.N., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4ka2: Crystal structure of CD4-mimetic miniprotein M48U12 in complex with HIV-1 YU2 gp120
Classification: Viral protein/INHIBITOR
Source organism: Human immunodeficiency virus 1; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.79 Å
Deposited: 2013-04-21
Authors: Acharya, P., Kwong, P.D.
PDB entry 4ka3: Structure of MAP kinase in complex with a docking peptide
Classification: TRANSFERASE/PROTEIN BINDING
Source organism: Homo sapiens; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.707 Å
Deposited: 2013-04-22
Authors: Xin, F.J., Wu, J.W.
PDB entry 4ka4: Crystal structure of a proteolytically defined Zbeta domain of human DAI (ZBP1, DLM-1)
Classification: DNA Binding Protein/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2013-04-22
Authors: Athanasiadis, A., de Rosa, M., De Sanctis, D.
PDB entry 4ka7: Structure of Organellar OligoPeptidase (E572Q) in complex with an endogenous substrate
Classification: HYDROLASE/HYDROLASE SUBSTRATE
Source organism: Arabidopsis thaliana; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-04-22
Authors: Berntsson, R.P.-A., Kmiec, B., Teixeira, P.F., Svensson, L.M., Bakali, A., Glaser, E., Stenmark, P.
PDB entry 4ka8: Structure of Organellar OligoPeptidase
Classification: HYDROLASE
Source organism: Arabidopsis thaliana
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2013-04-22
Authors: Berntsson, R.P.-A., Kmiec, B., Teixeira, P.F., Svensson, L.M., Bakali, A., Glaser, E., Stenmark, P.
PDB entry 4ka9: Crystal structure analysis of single amino acid deletion mutations in EGFP
Classification: FLUORESCENT PROTEIN
Source organism: Aequorea victoria
Experimental method: X-RAY DIFFRACTION
Resolution: 1.58 Å
Deposited: 2013-04-22
Authors: Arpino, J.A.J., Rizkallah, P.J.
PDB entry 4kaa: Crystal structure of the halotag2 protein at the resolution 2.3A, Northeast Structural Genomics Consortium (NESG) target OR150
Classification: HYDROLASE
Source organism: Rhodococcus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2.276 Å
Deposited: 2013-04-22
Authors: Kuzin, A., Lew, S., Neklesa, T.K., Noblin, D., Seetharaman, J., Maglaqui, M., Xiao, R., Kohan, E., Wang, H., Everett, J.K., Acton, T.B., Montelione, G.T., Hunt, J.F., Crews, C., Tong, L., Northeast Structural Genomics Consortium (NESG)
PDB entry 4kab: FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 3-Methyl-1,4-dihydro-pyrazolo[4,5-c]pyrazole
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.71 Å
Deposited: 2013-04-22
Authors: Musil, D., Graedler, U., Heinrich, T., Lehmann, M., Dresing, V.
PDB entry 4kac: X-Ray Structure of the complex HaloTag2 with HALTS. Northeast Structural Genomics Consortium (NESG) Target OR150.
Classification: HYDROLASE
Source organism: Rhodococcus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2.223 Å
Deposited: 2013-04-22
Authors: Kuzin, A., Lew, S., Neklesa, T.K., Noblin, D., Seetharaman, J., Maglaqui, M., Xiao, R., Kohan, E., Wang, H., Everett, J.K., Acton, T.B., Kornhaber, G., Montelione, G.T., Crews, C.M., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
PDB entry 4kad: Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with N1-(2.3-dihydro-1H-inden-5-yl)acetam
Classification: TRANSFERASE
Source organism: Rhizobium etli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2013-04-22
Authors: Malashkevich, V.N., Bhosle, R., Toro, R., Hillerich, B., Gizzi, A., Garforth, S., Kar, A., Chan, M.K., Lafluer, J., Patel, H., Matikainen, B., Chamala, S., Lim, S., Celikgil, A., Villegas, G., Evans, B., Love, J., Fiser, A., Khafizov, K., Seidel, R., Bonanno, J.B., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4kae: Crystal structure of Maleylacetoacetate isomerase from Anaeromyxobacter dehalogenans 2CP-1, TARGET EFI-507175, with bound dicarboxyethyl glutathione and citrate in the active site
Classification: ISOMERASE
Source organism: Anaeromyxobacter dehalogenans
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2013-04-22
Authors: Kim, J., Toro, R., Bhosle, R., Al Obaidi, N.F., Morisco, L.L., Wasserman, S.R., Sojitra, S., Washington, E., Scott Glenn, A., Chowdhury, S., Evans, B., Hammonds, J., Hillerich, B., Love, J., Seidel, R.D., Imker, H.J., Stead, M., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4kaf: Crystal Structure of Haloalkane dehalogenase HaloTag7 at the resolution 1.5A, Northeast Structural Genomics Consortium (NESG) Target OR151
Classification: HYDROLASE
Source organism: Rhodococcus sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 1.496 Å
Deposited: 2013-04-22
Authors: Kuzin, A.P., Lew, S., Neklesa, T.K., Noblin, D., Seetharaman, J., Maglaqui, M., Xiao, R., Kohan, E., Wang, H., Everett, J.K., Acton, T.B., Kornhaber, G., Montelione, G.T., Crews, C., Tong, L., Northeast Structural Genomics Consortium (NESG)
PDB entry 4kag: Crystal structure analysis of a single amino acid deletion mutation in EGFP
Classification: FLUORESCENT PROTEIN
Source organism: Aequorea victoria
Experimental method: X-RAY DIFFRACTION
Resolution: 1.12 Å
Deposited: 2013-04-22
Authors: Arpino, J.A.J., Rizkallah, P.J.
PDB entry 4kah: Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 4-bromo-1H-pyrazole
Classification: TRANSFERASE
Source organism: Rhizobium etli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-04-22
Authors: Malashkevich, V.N., Bhosle, R., Toro, R., Hillerich, B., Gizzi, A., Garforth, S., Kar, A., Chan, M.K., Lafluer, J., Patel, H., Matikainen, B., Chamala, S., Lim, S., Celikgil, A., Villegas, G., Evans, B., Love, J., Fiser, A., Khafizov, K., Seidel, R., Bonanno, J.B., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4kai: HCV NS5B GT1B N316 with GSK5852A
Classification: REPLICATION/REPLICATION INHIBITOR
Source organism: Hepatitis C virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2013-04-22
Authors: Williams, S.P., Kahler, K.M., Shotwell, J.B.
PDB entry 4kaj: X-Ray Structure of the complex of Haloalkane dehalogenase HaloTag7 with HALTS, Northeast Structural Genomics Consortium (NESG) Target OR151
Classification: HYDROLASE
Source organism: Rhodococcus sp.; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.948 Å
Deposited: 2013-04-22
Authors: Kuzin, A., Lew, S., Neklesa, T.K., Noblin, D., Seetharaman, J., Maglaqui, M., Xiao, R., Kohan, E., Wang, H., Everett, J.K., Acton, T.B., Kornhaber, G., Montelione, G.T., Crews, C.M., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
PDB entry 4kak: Crystal structure of human dihydrofolate reductase complexed with NADPH and 6-ethyl-5-[(3S)-3-[3-methoxy-5-(pyridine-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (UCP1006)
Classification: Oxidoreductase/oxidoreductase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-04-22
Authors: Lamb, K.M., Anderson, A.C.
PDB entry 4kal: Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with quinoline-3-carboxylic acid
Classification: TRANSFERASE
Source organism: Rhizobium etli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2013-04-22
Authors: Malashkevich, V.N., Bhosle, R., Toro, R., Hillerich, B., Gizzi, A., Garforth, S., Kar, A., Chan, M.K., Lafluer, J., Patel, H., Matikainen, B., Chamala, S., Lim, S., Celikgil, A., Villegas, G., Evans, B., Love, J., Fiser, A., Khafizov, K., Seidel, R., Bonanno, J.B., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4kam: X-ray crystal structure of O-acetylhomoserine sulfhydrylase MetC from Mycobacterium marinum ATCC BAA-535 / M
Classification: TRANSFERASE
Source organism: Mycobacterium marinum
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2013-04-22
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 4kan: Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 2-(2,5-dimethyl-1,3-thiazol-4-yl)acetic acid
Classification: TRANSFERASE
Source organism: Rhizobium etli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.51 Å
Deposited: 2013-04-22
Authors: Malashkevich, V.N., Bhosle, R., Toro, R., Hillerich, B., Gizzi, A., Garforth, S., Kar, A., Chan, M.K., Lafluer, J., Patel, H., Matikainen, B., Chamala, S., Lim, S., Celikgil, A., Villegas, G., Evans, B., Love, J., Fiser, A., Khafizov, K., Seidel, R., Bonanno, J.B., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4kao: FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-(4-pyridin-3- yl-phenyl)-urea
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.39 Å
Deposited: 2013-04-22
Authors: Musil, D., Graedler, U., Heinrich, T., Lehmann, M., Dresing, V.
PDB entry 4kap: The Binding of Benzoarylsulfonamide Ligands to Human Carbonic Anhydrase is Insensitive to Formal Fluorination of the Ligand
Classification: LYASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2013-04-22
Authors: Lange, H., Lockett, M.R., Breiten, B., Heroux, A., Sherman, W., Rappoport, D., Yau, P.O., Snyder, P.W., Whitesides, G.M.
PDB entry 4kaq: Structure of rituximab Fab
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens, Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.48 Å
Deposited: 2013-04-22
Authors: Bzymek, K.P., Williams, J.C.
PDB entry 4kar: Crystal structure of FDTS (TM0449) mutant (H53D) with FAD
Classification: TRANSFERASE
Source organism: Thermotoga maritima MSB8
Experimental method: X-RAY DIFFRACTION
Resolution: 2.03 Å
Deposited: 2013-04-22
Authors: Mathews, I.I.
PDB entry 4kas: Crystal structure of FDTS from T. maritima mutant (H53D) with FAD and dUMP
Classification: TRANSFERASE
Source organism: Thermotoga maritima
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2013-04-22
Authors: Mathews, I.I.
PDB entry 4kat: Crystal structure of FDTS from T. maritima mutant (R174K) with FAD and dUMP
Classification: TRANSFERASE
Source organism: Thermotoga maritima MSB8
Experimental method: X-RAY DIFFRACTION
Resolution: 2.14 Å
Deposited: 2013-04-22
Authors: Mathews, I.I.
PDB entry 4kav: Crystal Structure of the soluble domain of Lipooligosaccharide phosphoethanolamine transferase A from Neisseria meningitidis
Classification: TRANSFERASE
Source organism: Neisseria meningitidis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.433 Å
Deposited: 2013-04-23
Authors: Vrielink, A., Wanty, C.
PDB entry 4kaw: Crystal structure of ribosome recycling factor mutant R39G from Mycobacterium tuberculosis
Classification: TRANSLATION
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2013-04-23
Authors: Selvaraj, M., Govindan, A., Seshadri, A., Dubey, B., Varshney, U., Vijayan, M.
PDB entry 4kax: Crystal structure of the Grp1 PH domain in complex with Arf6-GTP
Classification: PROTEIN BINDING/SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2013-04-23
Authors: Lambright, D.G., Malaby, A.W., van den Berg, B.
PDB entry 4kay: Structure of the soluble domain of Lipooligosaccharide phosphoethanolamine transferase A from Neisseria meningitidis - complex with Zn
Classification: TRANSFERASE
Source organism: Neisseria meningitidis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.781 Å
Deposited: 2013-04-23
Authors: Vrielink, A., Wanty, C., Anandan, A.
PDB entry 4kaz: Crystal structure of RNase T in complex with a Y structured DNA
Classification: Hydrolase/dna
Source organism: Escherichia coli; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2013-04-23
Authors: Hsiao, Y.-Y., Yuan, H.S.
PDB entry 4kb0: Crystal structure of RNase T in complex with a bluge DNA (Two nucleotide insertion CC )
Classification: Hydrolase/dna
Source organism: Escherichia coli; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.004 Å
Deposited: 2013-04-23
Authors: Hsiao, Y.-Y., Yuan, H.S.
PDB entry 4kb1: Crystal structure of RNase T in complex with a bluge DNA (two nucleotide insertion CT )
Classification: Hydrolase/dna
Source organism: Escherichia coli; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-04-23
Authors: Hsiao, Y.-Y., Yuan, H.S.
PDB entry 4kb2: Crystal structure of ribosome recycling factor mutant R109A from Mycobacterium tuberculosis
Classification: TRANSLATION
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2013-04-23
Authors: Selvaraj, M., Govindan, A., Seshadri, A., Dubey, B., Varshney, U., Vijayan, M.
PDB entry 4kb3: Crystal structure of the mitochondrial peroxiredoxin from Leishmania braziliensis in the decameric form
Classification: OXIDOREDUCTASE
Source organism: Leishmania braziliensis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.93 Å
Deposited: 2013-04-23
Authors: Giuseppe, P.O., Souza, T.A.C.B., Morais, M.A.B., Murakami, M.T.
PDB entry 4kb4: Crystal structure of ribosome recycling factor mutant R31A from Mycobacterium tuberculosis
Classification: TRANSLATION
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.25 Å
Deposited: 2013-04-23
Authors: Selvaraj, M., Govindan, A., Seshadri, A., Dubey, B., Varshney, U., Vijayan, M.
PDB entry 4kb5: Crystal structure of MycP1 from Mycobacterium smegmatis
Classification: HYDROLASE
Source organism: Mycobacterium smegmatis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2013-04-23
Authors: Sun, D.M., He, Y., Tian, C.L.
PDB entry 4kb6: Structure of porcine cyclic GMP AMP synthase (CGAS) in complex with DNA, ATP and GTP
Classification: TRANSFERASE/DNA
Source organism: Sus scrofa; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.0754 Å
Deposited: 2013-04-23
Authors: Deimling, T., Hopfner, K.-P.
PDB entry 4kb7: HCV NS5B GT1B N316Y with CMPD 32
Classification: REPLICATION/REPLICATION INHIBITOR
Source organism: Hepatitis C virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2013-04-23
Authors: Williams, S.P., Kahler, K.M., Shotwell, J.B.
PDB entry 4kb8: CK1d in complex with 1-{4-[3-(4-FLUOROPHENYL)-1-METHYL-1H-PYRAZOL-4-YL]PYRIDIN-2-YL}-N-METHYLMETHANAMINE ligand
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2013-04-23
Authors: Liu, S.
PDB entry 4kb9: Crystal structure of wild-type HIV-1 protease with novel tricyclic P2-ligands GRL-0739A
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.29 Å
Deposited: 2013-04-23
Authors: Wang, Y.-F., Agniswamy, J., Weber, I.T.
PDB entry 4kba: CK1d in complex with 9-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-2,3,4,5-tetrahydropyrido[2,3-f][1,4]oxazepine inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2013-04-23
Authors: Liu, S.
PDB entry 4kbb: Structure of Botulinum neurotoxin B binding domain in complex with both synaptotagmin II and GD1a
Classification: Signaling Protein/Toxin
Source organism: Clostridium botulinum; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2013-04-23
Authors: Berntsson, R.P.A., Peng, L., Dong, M., Stenmark, P.
PDB entry 4kbc: CK1d in complex with {4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDIN-2-YL}METHANOL inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2013-04-23
Authors: Liu, S.
PDB entry 4kbd: DNA STRUCTURE OF A MUTATED KB SITE
Classification: DNA
Experimental method: SOLUTION NMR
Deposited: 1998-11-30
Authors: Tisne, C., Hartmann, B., Delepierre, M.
PDB entry 4kbe: Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with benzoguanamine
Classification: TRANSFERASE
Source organism: Rhizobium etli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2013-04-23
Authors: Malashkevich, V.N., Bhosle, R., Toro, R., Hillerich, B., Gizzi, A., Garforth, S., Kar, A., Chan, M.K., Lafluer, J., Patel, H., Matikainen, B., Chamala, S., Lim, S., Celikgil, A., Villegas, G., Evans, B., Love, J., Fiser, A., Khafizov, K., Seidel, R., Bonanno, J.B., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
PDB entry 4kbf: two different open conformations of the helicase core of the RNA helicase Hera
Classification: HYDROLASE
Source organism: Thermus thermophilus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2013-04-23
Authors: Rudolph, M.G., Klostermeier, D.
PDB entry 4kbg: almost closed conformation of the helicase core of the RNA helicase Hera
Classification: HYDROLASE
Source organism: Thermus thermophilus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.54 Å
Deposited: 2013-04-23
Authors: Rudolph, M.G., Klostermeier, D.
PDB entry 4kbi: HCV NS5B GT1B N316Y with CMPD 4
Classification: REPLICATION/REPLICATION INHIBITOR
Source organism: Hepatitis C virus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.06 Å
Deposited: 2013-04-23
Authors: Williams, S.P., Kahler, K.M., Shotwell, J.B.
PDB entry 4kbj: Structure of Mtb RNAP Beta subunit B1 and B2 domains
Classification: TRANSFERASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4532 Å
Deposited: 2013-04-23
Authors: Gulten, G., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
PDB entry 4kbk: CK1d in complex with (3S)-3-{4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]pyridin-2-yl}morpholine inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2013-04-23
Authors: Liu, S.
PDB entry 4kbl: Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.3 Å
Deposited: 2013-04-23
Authors: Duda, D.M., Olszewski, J.L., Schulman, B.A.
PDB entry 4kbm: Structure of the Mtb CarD/RNAP Beta subunit B1-B2 domains complex
Classification: TRANSFERASE/TRANSCRIPTION
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1146 Å
Deposited: 2013-04-23
Authors: Gulten, G., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
PDB entry 4kbn: human dihydrofolate reductase complexed with NADPH and 5-{3-[3-(3,5-pyrimidine)]-phenyl-prop-1-yn-1-yl}-6-ethyl-pyrimidine-2,4diamine
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.84 Å
Deposited: 2013-04-23
Authors: Lamb, K.M., Anderson, A.C.
PDB entry 4kbo: Crystal structure of the human Mortalin (GRP75) ATPase domain in the apo form
Classification: SIGNALING PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2013-04-23
Authors: Amick, J., Page, R.C., Nix, J.C., Misra, S.
PDB entry 4kbp: KIDNEY BEAN PURPLE ACID PHOSPHATASE
Classification: HYDROLASE (PHOSPHORIC MONOESTER)
Source organism: Phaseolus vulgaris
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 1995-10-02
Authors: Klabunde, T., Strater, N., Krebs, B.
PDB entry 4kbq: Structure of the CHIP-TPR domain in complex with the Hsc70 Lid-Tail domains
Classification: LIGASE/PROTEIN BINDING
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.91 Å
Deposited: 2013-04-23
Authors: Page, R.C., Amick, J., Nix, J.C., Misra, S.
PDB entry 4kbr: Crystal structure of mouse Ceramide-1-phosphate transfer protein (apo-form)
Classification: LIPID TRANSPORT
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.547 Å
Deposited: 2013-04-23
Authors: Simanshu, D.K., Brown, R.E., Patel, D.J.
PDB entry 4kbs: Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 12:0 phosphatidic acid (12:0 PA)
Classification: LIPID TRANSPORT
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.898 Å
Deposited: 2013-04-23
Authors: Simanshu, D.K., Brown, R.E., Patel, D.J.
PDB entry 4kbx: Crystal structure of the pyridoxal-5'-phosphate dependent protein yhfx from escherichia coli
Classification: UNKNOWN FUNCTION
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.599 Å
Deposited: 2013-04-24
Authors: Fedorov, A.A., Fedorov, E.V., Xiang, D.F., Raushel, F.M., Almo, S.C.
PDB entry 4kby: mSTING/c-di-GMP
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.36 Å
Deposited: 2013-04-24
Authors: Chin, K.H., Su, Y.C., Tu, J.L., Chou, S.H.
PDB entry 4kbz: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) with (S)-{2-[2-(5-Cyano-3-hydroxy-pyridin-2-yl)-thiazol-4-yl]-acetylamino}-phenyl-acetic acid
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2013-04-24
Authors: Kim, H.T., Hong, Y.R., Chang, H.J.
PDB entry 4kc0: mSTING
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2013-04-24
Authors: Chin, K.H., Su, Y.C., Tu, J.L., Chou, S.H.
PDB entry 4kc1: Structure of the blood group glycosyltransferase AAglyB in complex with a pyridine inhibitor as a neutral pyrophosphate surrogate
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2013-04-24
Authors: Cuesta-Seijo, J.A., Wang, S., Lafont, D., Vidal, S., Palcic, M.M.
PDB entry 4kc2: Structure of the blood group glycosyltransferase AAglyB in complex with a pyridine inhibitor as a neutral pyrophosphate surrogate
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2013-04-24
Authors: Cuesta-Seijo, J.A., Wang, S., Lafont, D., Vidal, S., Palcic, M.M.
PDB entry 4kc3: Cytokine/receptor binary complex
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.2702 Å
Deposited: 2013-04-24
Authors: Liu, X., Wang, X.Q.
PDB entry 4kc4: Structure of the blood group glycosyltransferase AAglyB in complex with a pyridine inhibitor as a neutral pyrophosphate surrogate
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2013-04-24
Authors: Cuesta-Seijo, J.A., Wang, S., Lafont, D., Vidal, S., Palcic, M.M.
PDB entry 4kc5: Crystal structure of the C-terminal part of RhiE from Burkholderia rhizoxinica
Classification: TRANSFERASE
Source organism: Burkholderia rhizoxinica
Experimental method: X-RAY DIFFRACTION
Resolution: 2.14 Å
Deposited: 2013-04-24
Authors: Zocher, G., Heim, J.B., Stehle, T.
PDB entry 4kc6: Crystal structure of C-terminal deletion mutant of ribosome recycling factor from Mycobacterium tuberculosis
Classification: TRANSLATION
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2013-04-24
Authors: Selvaraj, M., Govindan, A., Seshadri, A., Dubey, B., Varshney, U., Vijayan, M.
PDB entry 4kc7: Crystal Structure of Endo-1,5-alpha-L-arabinanase from Thermotoga petrophila RKU-1
Classification: HYDROLASE
Source organism: Thermotoga petrophila
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2013-04-24
Authors: Nascimento, A.F.Z., Polo, C.C., Santos, C.R., Costa, M.C.M.F., Mesa, A.N., Prade, R.A., Ruller, R., Squina, F.M., Murakami, M.T.
PDB entry 4kc8: Crystal Structure of Endo-1,5-alpha-L-arabinanase from Thermotoga petrophila RKU-1 in complex with TRIS
Classification: HYDROLASE
Source organism: Thermotoga petrophila
Experimental method: X-RAY DIFFRACTION
Resolution: 1.76 Å
Deposited: 2013-04-24
Authors: Nascimento, A.F.Z., Polo, C.C., Santos, C.R., Costa, M.C.M.F., Mesa, A.N., Prade, R.A., Ruller, R., Squina, F.M., Murakami, M.T.
PDB entry 4kc9: Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.603 Å
Deposited: 2013-04-24
Authors: Duda, D.M., Olszewski, J.L., Schulman, B.A.
PDB entry 4kca: Crystal Structure of Endo-1,5-alpha-L-arabinanase from a Bovine Ruminal Metagenomic Library
Classification: HYDROLASE
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2013-04-24
Authors: Santos, C.R., Polo, C.C., Costa, M.C.M.F., Nascimento, A.F.Z., Wong, D.W.S., Murakami, M.T.
PDB entry 4kcb: Crystal Structure of Exo-1,5-alpha-L-arabinanase from Bovine Ruminal Metagenomic Library
Classification: HYDROLASE
Source organism: uncultured bacterium
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2013-04-24
Authors: Santos, C.R., Polo, C.C., Costa, M.C.M.F., Nascimento, A.F.Z., Wong, D.W.S., Murakami, M.T.
PDB entry 4kcc: Crystal Structure of the NMDA Receptor GluN1 Ligand Binding Domain Apo State
Classification: MEMBRANE PROTEIN
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.894 Å
Deposited: 2013-04-24
Authors: Berger, A.J., Lau, A.Y., Mayer, M.L.
PDB entry 4kcd: Crystal Structure of the NMDA Receptor GluN3A Ligand Binding Domain Apo State
Classification: MEMBRANE PROTEIN
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.68 Å
Deposited: 2013-04-24
Authors: Yao, Y., Lau, A.Y., Mayer, M.L.
PDB entry 4kce: Crystal structure of the mitochondrial peroxiredoxin from Leishmania braziliensis in the dimeric form
Classification: OXIDOREDUCTASE
Source organism: Leishmania braziliensis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.79 Å
Deposited: 2013-04-24
Authors: Souza, T.A.C.B., Morais, M.A.B., Giuseppe, P.O., Murakami, M.T.
PDB entry 4kcf: X-ray Structure of a KijD3 in Complex with FMN and dTDP-3-amino-2,3,6-trideoxy-4-keto-3-methyl-D-glucose
Classification: OXIDOREDUCTASE
Source organism: Actinomadura kijaniata
Experimental method: X-RAY DIFFRACTION
Resolution: 2.098 Å
Deposited: 2013-04-24
Authors: Holden, H.M., Thoden, J.B., Branch, M.C., Zimmer, A.L., Bruender, N.A.
PDB entry 4kcg: Human dCK C4S-S74E mutant in complex with UDP and the DI-39 inhibitor
Classification: transferase/transferase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.09 Å
Deposited: 2013-04-24
Authors: Nomme, J., Lavie, A.
PDB entry 4kch: Structure of neuronal nitric oxide synthase heme domain in complex with N,N'-([1,1'-biphenyl]-3,3'-diyl)bis(thiophene-2-carboximidamide)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2013-04-24
Authors: Li, H., Poulos, T.L.
PDB entry 4kci: Structure of neuronal nitric oxide synthase heme domain in complex with N,N'-(ethane-1,2-diylbis(3,1-phenylene))bis(thiophene-2-carboximidamide)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.27 Å
Deposited: 2013-04-24
Authors: Li, H., Poulos, T.L.
PDB entry 4kcj: Structure of neuronal nitric oxide synthase heme domain in complex with N,N'-((ethane-1,2-diylbis(oxy))bis(3,1-phenylene))bis(thiophene-2-carboximidamide)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2013-04-24
Authors: Li, H., Poulos, T.L.
PDB entry 4kck: Structure of neuronal nitric oxide synthase heme domain in complex with N-(3-(2-((3-(thiophene-2-carboximidamido)benzyl)amino)ethyl)phenyl)thiophene-2-carboximidamide
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2013-04-24
Authors: Li, H., Poulos, T.L.
PDB entry 4kcl: Structure of neuronal nitric oxide synthase heme domain in complex with N-(4-(2-((3-(thiophene-2-carboximidamido)benzyl)amino)ethyl)phenyl)thiophene-2-carboximidamide
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.93 Å
Deposited: 2013-04-24
Authors: Li, H., Poulos, T.L.
PDB entry 4kcm: Structure of neuronal nitric oxide synthase heme domain in complex with N-(4-(2-(ethyl(3-(thiophene-2-carboximidamido)benzyl)amino)ethyl)phenyl)thiophene-2-carboximidamide
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.074 Å
Deposited: 2013-04-24
Authors: Li, H., Poulos, T.L.
PDB entry 4kcn: Structure of neuronal nitric oxide synthase heme domain in complex with N-(3-(((3-fluorophenethyl)amino)methyl)phenyl)thiophene-2-carboximidamide
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2013-04-24
Authors: Li, H., Poulos, T.L.
PDB entry 4kco: Structure of neuronal nitric oxide synthase heme domain in complex with N-(3-((ethyl(3-fluorophenethyl)amino)methyl)phenyl)thiophene-2-carboximidamide
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Rattus norvegicus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.86 Å
Deposited: 2013-04-24
Authors: Li, H., Poulos, T.L.
PDB entry 4kcp: Structure of bovine endotheial nitric oxide synthase heme domain in complex with N-(4-(2-((3-(thiophene-2-carboximidamido)benzyl)amino)ethyl)phenyl)thiophene-2-carboximidamide
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.07 Å
Deposited: 2013-04-24
Authors: Chreifi, G., Li, H., Poulos, T.L.
PDB entry 4kcq: Structure of bovine endothelial nitric oxide synthase heme domain in complex with N-(4-(2-(ethyl(3-(thiophene-2-carboximidamido)benzyl)amino)ethyl)phenyl)thiophene-2-carboximidamide
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.03 Å
Deposited: 2013-04-24
Authors: Li, H., Poulos, T.L.
PDB entry 4kcr: Structure of bovine endothelial nitric oxide synthase heme domain in complex with N-(3-(((3-fluorophenethyl)amino)methyl)phenyl)thiophene-2-carboximidamide
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.09 Å
Deposited: 2013-04-24
Authors: Li, H., Poulos, T.L.
PDB entry 4kcs: Structure of bovine endothelial nitric oxide synthase heme domain in complex with N-(3-((ethyl(3-fluorophenethyl)amino)methyl)phenyl)thiophene-2-carboximidamide
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2013-04-24
Authors: Chreifi, G., Li, H., Poulos, T.L.
PDB entry 4kct: Pyruvate kinase (PYK) from Trypanosoma brucei soaked with Oxaloacetate
Classification: TRANSFERASE
Source organism: Trypanosoma brucei brucei
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2013-04-24
Authors: Zhong, W., Morgan, H.P., McNae, I.W., Michels, P.A.M., Fothergill-Gilmore, L.A., Walkinshaw, M.D.