LiteFold/PDB huggingface dataset:
PDB entry 5tyd: DNA Polymerase Mu Reactant Complex, 10 mM Mg2+ (45 min)
Classification: Transferase/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.899 Å
Deposited: 2016-11-19
Authors: Jamsen, J.A., Wilson, S.H.
PDB entry 5tye: DNA Polymerase Mu Product Complex, 10 mM Mg2+ (60 min)
Classification: Transferase/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.047 Å
Deposited: 2016-11-19
Authors: Jamsen, J.A., Wilson, S.H.
PDB entry 5tyf: DNA Polymerase Mu Product Complex, 10 mM Mg2+ (270 min)
Classification: Transferase/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.971 Å
Deposited: 2016-11-19
Authors: Jamsen, J.A., Wilson, S.H.
PDB entry 5tyg: DNA Polymerase Mu Product Complex, 10 mM Mg2+ (960 min)
Classification: Transferase/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.726 Å
Deposited: 2016-11-19
Authors: Jamsen, J.A., Wilson, S.H.
PDB entry 5tyh: PglD from Campylobacter jejuni NCTC 11168 in complex with 5-(2-furanyl)-1H-pyrazole-3-carboxylic acid
Classification: transferase/transferase inhibitor
Source organism: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2016-11-20
Authors: Morrison, J.P., Imperiali, B.
PDB entry 5tyi: Grb7 SH2 with bicyclic peptide containing pY mimetic
Classification: Signaling Protein/Peptide
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2016-11-20
Authors: Watson, G.M., Wilce, M.C.J., Wilce, J.A.
PDB entry 5tyj: alpha-esterase-7 in complex with (3-bromo-5-phenoxylphenyl)boronic acid
Classification: hydrolase/hydrolase inhibitor
Source organism: Lucilia cuprina
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2016-11-20
Authors: Correy, G.J., Jackson, C.J.
PDB entry 5tyk: alpha-esterase-7 in complex with 3-chloro-4-[(2-fluorophenyl)methoxy]phenylborinic acid
Classification: hydrolase/hydrolase inhibitor
Source organism: Lucilia cuprina
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2016-11-21
Authors: Correy, G.J., Jackson, C.J.
PDB entry 5tyl: alpha-esterase-7 in complex with naphthalen-2-ylboronic acid
Classification: hydrolase/hydrolase inhibitor
Source organism: Lucilia cuprina
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2016-11-21
Authors: Correy, G.J., Jackson, C.J.
PDB entry 5tym: alpha-esterase-7 in complex with [3-bromo-5-(pyrrolidin-1-yl)phenyl]borinic acid
Classification: hydrolase/hydrolase inhibitor
Source organism: Lucilia cuprina
Experimental method: X-RAY DIFFRACTION
Resolution: 1.84 Å
Deposited: 2016-11-21
Authors: Correy, G.J., Jackson, C.J.
PDB entry 5tyn: alpha-esterase-7 in complex with [3-bromo-5-(pyrrolidin-1-yl)phenyl]borinic acid
Classification: hydrolase/hydrolase inhibitor
Source organism: Lucilia cuprina
Experimental method: X-RAY DIFFRACTION
Resolution: 1.531 Å
Deposited: 2016-11-21
Authors: Correy, G.J., Jackson, C.J.
PDB entry 5tyo: alpha-esterase-7 in complex with [3-(benzyloxy)-4-methylphenyl]borinic acid
Classification: hydrolase/hydrolase inhibitor
Source organism: Lucilia cuprina
Experimental method: X-RAY DIFFRACTION
Resolution: 1.57 Å
Deposited: 2016-11-21
Authors: Correy, G.J., Jackson, C.J.
PDB entry 5typ: alpha-esterase-7 in complex with (3-bromo-4-methylphenyl)boronic acid
Classification: hydrolase/hydrolase inhibitor
Source organism: Lucilia cuprina
Experimental method: X-RAY DIFFRACTION
Resolution: 1.88 Å
Deposited: 2016-11-21
Authors: Correy, G.J., Jackson, C.J.
PDB entry 5tyq: Crystal structure of a holoenzyme methyltransferase involved in the biosynthesis of gentamicin
Classification: TRANSFERASE
Source organism: Micromonospora echinospora
Experimental method: X-RAY DIFFRACTION
Resolution: 2.163 Å
Deposited: 2016-11-21
Authors: Bury, P., Huang, F., Leadlay, P., Dias, M.V.B.
PDB entry 5tyr: X-ray crystal structure of wild type HIV-1 protease in complex with GRL-121
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2016-11-21
Authors: Yedidi, R.S., Hayashi, H., Aoki, M., Das, D., Ghosh, A.K., Mitsuya, H.
PDB entry 5tys: X-ray crystal structure of wild type HIV-1 protease in complex with GRL-142
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Human immunodeficiency virus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.007 Å
Deposited: 2016-11-21
Authors: Yedidi, R.S., Hayashi, H., Aoki, M., Das, D., Ghosh, A.K., Mitsuya, H.
PDB entry 5tyt: Crystal Structure of the PDZ domain of RhoGEF bound to CXCR2 C-terminal peptide
Classification: PROTEIN BINDING
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.398 Å
Deposited: 2016-11-21
Authors: Spellmon, N., Holcomb, J., Niu, A., Choudhary, V., Sun, X., Brunzelle, J., Li, C., Yang, Z.
PDB entry 5tyu: DNA Polymerase Mu Reactant Complex, Mn2+ (4 min)
Classification: Transferase/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.048 Å
Deposited: 2016-11-21
Authors: Jamsen, J.A., Wilson, S.H.
PDB entry 5tyv: DNA Polymerase Mu Reactant Complex, Mn2+ (7.5 min)
Classification: Transferase/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.93 Å
Deposited: 2016-11-21
Authors: Jamsen, J.A., Wilson, S.H.
PDB entry 5tyw: DNA Polymerase Mu Reactant Complex, Mn2+ (10 min)
Classification: Transferase/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.88 Å
Deposited: 2016-11-21
Authors: Jamsen, J.A., Wilson, S.H.
PDB entry 5tyx: DNA Polymerase Mu Product Complex, Mn2+ (15 min)
Classification: Transferase/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.948 Å
Deposited: 2016-11-21
Authors: Jamsen, J.A., Wilson, S.H.
PDB entry 5tyy: DNA Polymerase Mu Product Complex, Mn2+ (60 min)
Classification: Transferase/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.931 Å
Deposited: 2016-11-21
Authors: Jamsen, J.A., Wilson, S.H.
PDB entry 5tyz: DNA Polymerase Mu Product Complex, Mn2+ (960 min)
Classification: Transferase/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.977 Å
Deposited: 2016-11-21
Authors: Jamsen, J.A., Wilson, S.H.
PDB entry 5tz0: Structure of the Fremyella diplosiphon Fluorescence Recovery Protein
Classification: PROTEIN BINDING
Source organism: Tolypothrix sp. PCC 7601
Experimental method: X-RAY DIFFRACTION
Resolution: 3.025 Å
Deposited: 2016-11-21
Authors: Sutter, M., Pawlowski, E.G., Kerfeld, C.A.
PDB entry 5tz1: Crystal structure of sterol 14-alpha demethylase (CYP51) from Candida albicans in complex with the tetrazole-based antifungal drug candidate VT1161 (VT1)
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Source organism: Candida albicans
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2016-11-21
Authors: Hargrove, T., Wawrzak, Z., Lepesheva, G.
PDB entry 5tz2: Crystal structure of human CD47 ECD bound to Fab of C47B222
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.302 Å
Deposited: 2016-11-21
Authors: Cardoso, R.M.F.
PDB entry 5tz3: CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 2A IN COMPLEX with [1,2,4]triazolo[1,5-a]pyrimidin-7-yl}-N-(naphthalene-2-yl)piperidine-3-carboxamide
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.72 Å
Deposited: 2016-11-21
Authors: Xu, R., Aertgeerts, K.
PDB entry 5tz5: Crystal Structure of CurK Dehydratase H996F Inactive Mutant
Classification: LYASE
Source organism: Moorea producens 3L
Experimental method: X-RAY DIFFRACTION
Resolution: 1.428 Å
Deposited: 2016-11-21
Authors: Dodge, G.J., Smith, J.L.
PDB entry 5tz6: Crystal Structure of CurJ Dehydratase H978F Inactive Mutant In Complex with Compound 21
Classification: lyase/lyase inhibitor
Source organism: Moorea producens 3L
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2016-11-21
Authors: Dodge, G.J., Smith, J.L.
PDB entry 5tz7: Crystal Structure of CurK Dehydratase D1169N Inactive Mutant
Classification: LYASE
Source organism: Moorea producens 3L
Experimental method: X-RAY DIFFRACTION
Resolution: 1.648 Å
Deposited: 2016-11-21
Authors: Dodge, G.J., Smith, J.L.
PDB entry 5tz8: Crystal structure of S. aureus TarS
Classification: TRANSFERASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 4 Å
Deposited: 2016-11-21
Authors: Worrall, L.J., Sobhanifar, S., King, D.T., Strynadka, N.C.
PDB entry 5tza: CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 2A WITH 3-{5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl-1-[(naphthalene-2-yl)carbonyl]piperidine
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2016-11-21
Authors: Xu, R., Aertgeerts, K.
PDB entry 5tzb: Burkholderia sp. beta-aminopeptidase
Classification: HYDROLASE
Source organism: Burkholderia sp. LK4
Experimental method: X-RAY DIFFRACTION
Resolution: 1.977 Å
Deposited: 2016-11-21
Authors: McGowan, S., Drinkwater, N., John, M., Dumsday, G.
PDB entry 5tzc: Crystal Structure of human PDE2a in complex with (5S)-1-[(3-bromo-4-fluorophenyl)carbonyl]-3,3-difluoro-5-{5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}piperidine
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.36 Å
Deposited: 2016-11-21
Authors: Xu, R., Aertgeerts, K.
PDB entry 5tzd: Structure of the WT S. venezulae BldD-(CTD-c-di-GMP)2 assembly intermediate
Classification: DNA BINDING PROTEIN
Source organism: Streptomyces venezuelae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.749 Å
Deposited: 2016-11-21
Authors: Schumacher, M.
PDB entry 5tze: Crystal structure of S. aureus TarS in complex with UDP-GlcNAc
Classification: TRANSFERASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.33 Å
Deposited: 2016-11-21
Authors: Worrall, L.J., Sobhanifar, S., King, D.T., Strynadka, N.C.
PDB entry 5tzf: Structure of the BldD CTD(D116A)-(c-di-GMP)2 intermediate, form 1
Classification: DNA BINDING PROTEIN
Source organism: Streptomyces venezuelae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2016-11-21
Authors: Schumacher, M.A.
PDB entry 5tzg: Structure of the BldD CTD(D116A)-(c-di-GMP)2, form 2
Classification: DNA BINDING PROTEIN
Source organism: Streptomyces venezuelae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2016-11-21
Authors: Schumacher, M.A.
PDB entry 5tzh: CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 2A IN COMPLEX WITH 3,3-difluoro-1-[(4-fluorophenyl)carbonyl]-5-{5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}piperidine
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2016-11-21
Authors: Xu, R., Aertgeerts, K.
PDB entry 5tzi: Crystal structure of S. aureus TarS 1-349
Classification: TRANSFERASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2016-11-21
Authors: Worrall, L.J., Sobhanifar, S., King, D.T., Strynadka, N.C.
PDB entry 5tzj: Crystal structure of S. aureus TarS 1-349 in complex with UDP-GlcNAc
Classification: TRANSFERASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2016-11-21
Authors: Worrall, L.J., Sobhanifar, S., King, D.T., Strynadka, N.C.
PDB entry 5tzk: Crystal structure of S. aureus TarS 1-349 in complex with UDP
Classification: TRANSFERASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.22 Å
Deposited: 2016-11-21
Authors: Worrall, L.J., Sobhanifar, S., King, D.T., Strynadka, N.C.
PDB entry 5tzl: Structure of transthyretin in complex with the kinetic stabilizer 201
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2016-11-21
Authors: Connelly, S., Mortenson, D.E., Choi, S., Wilson, I.A., Powers, E.T., Kelly, J.W., Johnson, S.M.
PDB entry 5tzm: 59th Ig domain of human obscurin (OBSCN Ig59)
Classification: STRUCTURAL PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.177 Å
Deposited: 2016-11-21
Authors: Wright, N.T., Berndsen, C.E., Policke, R.A.
PDB entry 5tzn: Structure of the viral immunoevasin m12 (Smith) bound to the natural killer cell receptor NKR-P1B (B6)
Classification: IMMUNE SYSTEM/VIRAL PROTEIN
Source organism: Murid herpesvirus 1; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2016-11-22
Authors: Berry, R., Rossjohn, J.
PDB entry 5tzo: Computationally Designed Fentanyl Binder - Fen49*-Complex
Classification: HYDROLASE
Source organism: Bacillus subtilis (strain 168)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.67 Å
Deposited: 2016-11-22
Authors: Bick, M.J., Greisen, P.J., Morey, K.J., Antunes, M.S., La, D., Sankaran, B., Reymond, L., Johnsson, K., Medford, J.I., Baker, D.
PDB entry 5tzp: Crystal structure of FPV039:Bik BH3 complex
Classification: APOPTOSIS
Source organism: Fowlpox virus (strain NVSL); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.35 Å
Deposited: 2016-11-22
Authors: Anasir, M.I., Kvansakul, M.
PDB entry 5tzq: Crystal Structure of FPV039:Bmf BH3 complex
Classification: APOPTOSIS
Source organism: Fowlpox virus (strain NVSL); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2016-11-22
Authors: Anasir, M.I., Kvansakul, M.
PDB entry 5tzr: GPR40 in complex with partial agonist MK-8666
Classification: FATTY ACID BINDING PROTEIN/HYDROLASE
Source organism: Enterobacteria phage T4; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2016-11-22
Authors: Lu, J., Byrne, N., Patel, S., Sharma, S., Soisson, S.M.
PDB entry 5tzs: Architecture of the yeast small subunit processome
Classification: TRANSLATION
Source organism: Saccharomyces cerevisiae S288c
Experimental method: ELECTRON MICROSCOPY
Resolution: 5.1 Å
Deposited: 2016-11-22
Authors: Chaker-Margot, M., Barandun, J., Hunziker, M., Klinge, S.
PDB entry 5tzt: Crystal structure of human CD47 ECD bound to Fab of C47B161
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.89 Å
Deposited: 2016-11-22
Authors: Cardoso, R.M.F.
PDB entry 5tzu: Crystal structure of human CD47 ECD bound to Fab of B6H12.2
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2016-11-22
Authors: Cardoso, R.M.F.
PDB entry 5tzv: Binary complex crystal structure of DNA Polymerase Beta with G:T mismatch at the primer terminus
Classification: Transferase/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2016-11-22
Authors: Wilson, S.H., Batra, V.K.
PDB entry 5tzw: CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 2A IN COMPLEX WITH 1-[(3,4-difluorophenyl)carbonyl]-3,3-difluoro-5-{5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}piperidine
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.59 Å
Deposited: 2016-11-22
Authors: Xu, R., Aertgeerts, K.
PDB entry 5tzx: CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 2A IN COMPLEX WITH 1-[(3-chloro-4-fluorophenyl)carbonyl]-3,3-difluoro-5-{5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}piperidine
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2016-11-22
Authors: Xu, R., Aertgeerts, K.
PDB entry 5tzy: GPR40 in complex with AgoPAM AP8 and partial agonist MK-8666
Classification: FATTY ACID BINDING PROTEIN/HYDROLASE
Source organism: Enterobacteria phage T4; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.22 Å
Deposited: 2016-11-22
Authors: Lu, J., Byrne, N., Patel, S., Sharma, S., Soisson, S.M.
PDB entry 5tzz: CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 2A IN COMPLEX WITH 1-[(3-bromo-4-fluorophenyl)carbonyl]-3,3-difluoro-5-{5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}piperidine
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2016-11-22
Authors: Xu, R., Aertgeerts, K.
PDB entry 5u00: CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 2A IN COMPLEX WITH 3,3-difluoro-1-[(4-fluoro-3-iodophenyl)carbonyl]-5-{5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}piperidine
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.41 Å
Deposited: 2016-11-22
Authors: Xu, R., Aertgeerts, K.
PDB entry 5u01: Cooperative DNA binding by two RelA dimers
Classification: TRANSCRIPTION/DNA
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2016-11-22
Authors: Ghosh, G., Huang, D.
PDB entry 5u02: Crystal structure of S. aureus TarS 217-571
Classification: TRANSFERASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.301 Å
Deposited: 2016-11-22
Authors: Worrall, L.J., Sobhanifar, S., King, D.T., Strynadka, N.C.
PDB entry 5u03: Cryo-EM structure of the human CTP synthase filament
Classification: LIGASE, PROTEIN FIBRIL
Source organism: Homo sapiens
Experimental method: ELECTRON MICROSCOPY
Resolution: 6.1 Å
Deposited: 2016-11-22
Authors: Lynch, E.M., Kollman, J.M.
PDB entry 5u04: Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase
Classification: VIRAL PROTEIN
Source organism: Zika virus (strain Mr 766)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2016-11-22
Authors: Godoy, A.S., Lima, G.M.A., Oliveira, K.I.Z., Torres, N.U., Maluf, F.V., Guido, R.V.C., Oliva, G.
PDB entry 5u05: Cryo-EM structure of the E. coli CTP synthase tetramer
Classification: LIGASE
Source organism: Escherichia coli
Experimental method: ELECTRON MICROSCOPY
Resolution: 7.9 Å
Deposited: 2016-11-22
Authors: Lynch, E.M., Hicks, D.R., Kollman, J.M.
PDB entry 5u06: Grb7-SH2 with bicyclic peptide inhibitor containing a pY mimetic
Classification: SIGNALING PROTEIN/INHIBITOR
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2016-11-22
Authors: Watson, G.M., Wilce, J.A.
PDB entry 5u07: CRISPR RNA-guided surveillance complex
Classification: IMMUNE SYSTEM
Source organism: Thermobifida fusca YX; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.8 Å
Deposited: 2016-11-23
Authors: Xiao, Y., Luo, M., Hayes, R.P., Kim, J., Ng, S., Ding, F., Liao, M., Ke, A.
PDB entry 5u08: Crystal structure of an aminoglycoside acetyltransferase meta-AAC0020 from an uncultured soil metagenomic sample in complex with sisomicin
Classification: TRANSFERASE/ANTIBIOTIC
Source organism: uncultured bacterium
Experimental method: X-RAY DIFFRACTION
Resolution: 1.52 Å
Deposited: 2016-11-23
Authors: Xu, Z., Skarina, T., Wawrzak, Z., Stogios, P.J., Yim, V., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5u09: High-resolution crystal structure of the human CB1 cannabinoid receptor
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens; Pyrococcus abyssi (strain GE5 / Orsay)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2016-11-23
Authors: Shao, Z.H., Yin, J., Rosenbaum, D.
PDB entry 5u0a: CRISPR RNA-guided surveillance complex
Classification: IMMUNE SYSTEM
Source organism: Thermobifida fusca (strain YX); SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.3 Å
Deposited: 2016-11-23
Authors: Xiao, Y., Luo, M., Hayes, R.P., Kim, J., Ng, S., Ding, F., Liao, M., Ke, A.
PDB entry 5u0b: Structure of full-length Zika virus NS5
Classification: TRANSFERASE
Source organism: Zika virus (strain Mr 766)
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2016-11-23
Authors: Zhao, B., Du, F.
PDB entry 5u0c: Structure of Zika virus NS5 RNA polymerase domain
Classification: TRANSFERASE
Source organism: Zika virus (strain Mr 766)
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2016-11-23
Authors: Zhao, B., Du, F.
PDB entry 5u0d: Identification of a New Zinc Binding Chemotype by Fragment Screening
Classification: LYASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.59 Å
Deposited: 2016-11-23
Authors: Peat, T.S., Poulsen, S.A., Ren, B., Dolezal, O., Woods, L.A., Mujumdar, P., Chrysanthopoulos, P.K.
PDB entry 5u0e: Identification of a New Zinc Binding Chemotype by Fragment Screening
Classification: LYASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.27 Å
Deposited: 2016-11-23
Authors: Peat, T.S., Poulsen, S.A., Ren, B., Dolezal, O., Woods, L.A., Mujumdar, P., Chrysanthopoulos, P.K.
PDB entry 5u0f: Identification of a New Zinc Binding Chemotype by Fragment Screening
Classification: LYASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.21 Å
Deposited: 2016-11-23
Authors: Peat, T.S., Poulsen, S.A., Ren, B., Dolezal, O., Woods, L.A., Mujumdar, P., Chrysanthopoulos, P.K.
PDB entry 5u0g: Identification of a New Zinc Binding Chemotype by Fragment Screening
Classification: LYASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.54 Å
Deposited: 2016-11-23
Authors: Peat, T.S., Poulsen, S.A., Ren, B., Dolezal, O., Woods, L.A., Mujumdar, P., Chrysanthopoulos, P.K.
PDB entry 5u0h: Crystal structure of GH family 9 endoglucanase J30
Classification: HYDROLASE
Source organism: Thermobacillus composti KWC4
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2016-11-24
Authors: Ellinghaus, T.L., Pereira, J.H., McAndrew, R.P., Welner, D.H., Adams, P.D.
PDB entry 5u0i: C-terminal ankyrin repeats from human kidney-type glutaminase (KGA) - tetragonal crystal form
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.423 Å
Deposited: 2016-11-24
Authors: Pasquali, C.C., Gonzalez, A., Dias, S.M.G., Ambrosio, A.L.B.
PDB entry 5u0j: C-terminal ankyrin repeats from human kidney-type glutaminase (KGA) - monoclinic crystal form
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.72 Å
Deposited: 2016-11-24
Authors: Pasquali, C.C., Gonzalez, A., Dias, S.M.G., Ambrosio, A.L.B.
PDB entry 5u0k: C-terminal ankyrin repeats from human liver-type glutaminase (GAB/LGA)
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.548 Å
Deposited: 2016-11-24
Authors: Ferreira, I.M., Pasquali, C.C., Gonzalez, A., Dias, S.M.G., Ambrosio, A.L.B.
PDB entry 5u0l: X-ray crystal structure of fatty aldehyde dehydrogenase enzymes from Marinobacter aquaeolei VT8 complexed with a substrate
Classification: OXIDOREDUCTASE
Source organism: Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.285 Å
Deposited: 2016-11-24
Authors: Shi, K., Mulliner, K., Barney, B.M., Aihara, H.
PDB entry 5u0m: Fatty aldehyde dehydrogenase from Marinobacter aquaeolei VT8 and cofactor complex
Classification: OXIDOREDUCTASE
Source organism: Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.075 Å
Deposited: 2016-11-24
Authors: Shi, K., Mulliner, K., Barney, B.M., Aihara, H.
PDB entry 5u0n: Crystal structure of a methyltransferase in complex with the substrate involved in the biosynthesis of gentamicin
Classification: TRANSFERASE
Source organism: Micromonospora echinospora
Experimental method: X-RAY DIFFRACTION
Resolution: 2.115 Å
Deposited: 2016-11-25
Authors: Bury, P., Huang, F., Li, S., Sun, Y., Leadlay, P., Dias, M.V.B.
PDB entry 5u0p: Cryo-EM structure of the transcriptional Mediator
Classification: TRANSCRIPTION
Source organism: Schizosaccharomyces pombe
Experimental method: ELECTRON MICROSCOPY
Resolution: 4.4 Å
Deposited: 2016-11-26
Authors: Tsai, K.-L., Yu, X., Gopalan, S., Chao, T.-C., Zhang, Y., Florens, L., Washburn, M.P., Murakami, K., Conaway, R.C., Conaway, J.W., Asturias, F.
PDB entry 5u0q: RNA-DNA heptamer duplex with one 2'-5'-linkage
Classification: RNA, DNA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.43 Å
Deposited: 2016-11-26
Authors: Luo, Z., Sheng, J.
PDB entry 5u0r: Crystal Structure of DH270.UCA1 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.295 Å
Deposited: 2016-11-26
Authors: Fera, D., Harrison, S.C.
PDB entry 5u0s: Cryo-EM structure of the Mediator-RNAPII complex
Classification: TRANSCRIPTION/TRANSFERASE
Source organism: Schizosaccharomyces pombe
Experimental method: ELECTRON MICROSCOPY
Resolution: 7.8 Å
Deposited: 2016-11-26
Authors: Tsai, K.-L., Yu, X., Gopalan, S., Chao, T.-C., Zhang, Y., Florens, L., Washburn, M.P., Murakami, K., Conaway, R.C., Conaway, J.W., Asturias, F.
PDB entry 5u0t: Crystal structure of a methyltransferase involved in the biosynthesis of gentamicin in complex with (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-3-(methylamino)-alpha-D-glucopyranosyl]oxy}-2-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside
Classification: TRANSFERASE
Source organism: Micromonospora echinospora
Experimental method: X-RAY DIFFRACTION
Resolution: 2.109 Å
Deposited: 2016-11-27
Authors: Bury, P., Huang, F., Leadlay, P., Dias, M.V.B.
PDB entry 5u0u: Crystal Structure of DH270.1 (unliganded, single-chain Fv) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.428 Å
Deposited: 2016-11-27
Authors: Fera, D., Harrison, S.C.
PDB entry 5u0v: E. coli dihydropteroate synthase complexed with 6-methylamino-5-nitrosoisocytosine
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2016-11-27
Authors: Peat, T.S., Dennis, M.L., Swarbrick, J.D.
PDB entry 5u0w: E. coli dihydropteroate synthase complexed with 9-methylguanine
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.968 Å
Deposited: 2016-11-27
Authors: Chhabra, S., Dennis, M.L., Peat, T.S., Swarbrick, J.D.
PDB entry 5u0y: E. coli dihydropteroate synthase complexed with an 8-mercaptoguanine derivative: [(2-amino-6-oxo-6,9-dihydro-1H-purin-8-yl)sulfanyl]acetic acid
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.88 Å
Deposited: 2016-11-27
Authors: Dennis, M.L., Peat, T.S., Swarbrick, J.D.
PDB entry 5u0z: E. coli dihydropteroate synthase complexed with an 8-mercaptoguanine derivative
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.29 Å
Deposited: 2016-11-27
Authors: Dennis, M.L., Peat, T.S., Swarbrick, J.D.
PDB entry 5u10: E. coli dihydropteroate synthase complexed with pteroic acid
Classification: TRANSFERASE
Source organism: Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.04 Å
Deposited: 2016-11-27
Authors: Dennis, M.L., Peat, T.S., Swarbrick, J.D.
PDB entry 5u11: E. coli dihydropteroate synthase complexed with an 8-mercaptoguanine derivative: 2-[(2-amino-6-oxo-6,9-dihydro-1H-purin-8-yl)sulfanyl]-N-methylacetamide
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.994 Å
Deposited: 2016-11-27
Authors: Dennis, M.L., Peat, T.S., Swarbrick, J.D.
PDB entry 5u12: E. coli dihydropteroate synthase complexed with an 8-mercaptoguanine derivative: 2-azanyl-8-[(2-fluorophenyl)methylsulfanyl]-1,9-dihydropurin-6-one
Classification: TRANSFERASE
Source organism: Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.839 Å
Deposited: 2016-11-27
Authors: Dennis, M.L., Peat, T.S., Swarbrick, J.D.
PDB entry 5u13: E. coli dihydropteroate synthase complexed with an 8-mercaptoguanine derivative: 2-amino-8-{[2-(4-methoxyphenyl)-2-oxoethyl]sulfanyl}-1,7-dihydro-6H-purin-6-one
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.951 Å
Deposited: 2016-11-27
Authors: Dennis, M.L., Peat, T.S., Swarbrick, J.D.
PDB entry 5u14: E. coli dihydropteroate synthase complexed with an 8-mercaptoguanine derivative: 4-{2-[(2-amino-6-oxo-6,9-dihydro-1H-purin-8-yl)sulfanyl]ethyl}benzene-1-sulfonamide
Classification: TRANSFERASE
Source organism: Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.953 Å
Deposited: 2016-11-27
Authors: Dennis, M.L., Peat, T.S., Swarbrick, J.D.
PDB entry 5u15: Crystal Structure of DH270.UCA3 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.26 Å
Deposited: 2016-11-27
Authors: Fera, D., Harrison, S.C.
PDB entry 5u16: Structure of human MR1-2-OH-1-NA in complex with human MAIT A-F7 TCR
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2016-11-27
Authors: Keller, A.N., Birkinshaw, R.W., Rossjohn, J.
PDB entry 5u17: Structure of human MR1-DA-6-FP in complex with human MAIT A-F7 TCR
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2016-11-28
Authors: Keller, A.N., Rossjohn, J.
PDB entry 5u18: Crystal structure of a methyltransferase involved in the biosynthesis of gentamicin in complex with the Geneticin
Classification: TRANSFERASE
Source organism: Micromonospora echinospora
Experimental method: X-RAY DIFFRACTION
Resolution: 2.195 Å
Deposited: 2016-11-28
Authors: Bury, P., Huang, F., Leadlay, P., Dias, M.V.B.
PDB entry 5u19: Crystal structure of a methyltransferase involved in the biosynthesis of gentamicin in complex with (1R,2S,3S,4R,6R)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside
Classification: TRANSFERASE
Source organism: Micromonospora echinospora
Experimental method: X-RAY DIFFRACTION
Resolution: 1.902 Å
Deposited: 2016-11-28
Authors: Bury, P., Huang, F., Leadlay, P., Dias, M.V.B.
PDB entry 5u1a: Ferritin with Gc MtrE loop 1 inserted at His34
Classification: OXIDOREDUCTASE
Source organism: Helicobacter pylori; Neisseria gonorrhoeae
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2016-11-28
Authors: Wang, S.
PDB entry 5u1b: Ferritin with Gc MtrE loop2 inserted at the N-terminus
Classification: OXIDOREDUCTASE
Source organism: Helicobacter pylori; Neisseria gonorrhoeae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.81 Å
Deposited: 2016-11-28
Authors: Wang, S.
PDB entry 5u1c: Structure of tetrameric HIV-1 Strand Transfer Complex Intasome
Classification: VIRAL PROTEIN
Source organism: Human immunodeficiency virus 1; Sulfolobus solfataricus; SYNTHETIC CONSTRUCT
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.9 Å
Deposited: 2016-11-28
Authors: Lyumkis, D., Passos, D.
PDB entry 5u1d: Cryo-EM structure of the human TAP ATP-Binding Cassette Transporter
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens; Human herpesvirus 1
Experimental method: ELECTRON MICROSCOPY
Resolution: 3.97 Å
Deposited: 2016-11-28
Authors: Oldham, M.L., Chen, J., Grigorieff, N.
PDB entry 5u1e: Crystal structure of a methyltransferase involved in the biosynthesis of gentamicin in complex with the kanamycin B
Classification: TRANSFERASE
Source organism: Micromonospora echinospora
Experimental method: X-RAY DIFFRACTION
Resolution: 2.213 Å
Deposited: 2016-11-28
Authors: Bury, P., Huang, F., Leadlay, P., Dias, M.V.B.
PDB entry 5u1f: Initial contact of HIV-1 Env with CD4: Cryo-EM structure of BG505 DS-SOSIP trimer in complex with CD4 and antibody PGT145
Classification: VIRAL PROTEIN/IMMUNE SYSTEM
Source organism: Homo sapiens; Human immunodeficiency virus 1
Experimental method: ELECTRON MICROSCOPY
Resolution: 6.8 Å
Deposited: 2016-11-28
Authors: Acharya, P., Kwong, P.D., Potter, C.S., Carragher, B.
PDB entry 5u1g: Structure of TP228 ParA-AMPPNP-ParB complex
Classification: CELL CYCLE, REPLICATION
Source organism: unidentified plasmid
Experimental method: X-RAY DIFFRACTION
Resolution: 3.64 Å
Deposited: 2016-11-28
Authors: Schumacher, M.A.
PDB entry 5u1h: Crystal structure of the C-terminal peptidoglycan binding domain of OprF (PA1777) from Pseudomonas aeruginosa
Classification: PEPTIDE BINDING PROTEIN
Source organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2016-11-28
Authors: Watanabe, N., Stogios, P.J., Skarina, T., Wawrzak, Z., Di Leo, R., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5u1i: Crystal structure of a methyltransferase involved in the biosynthesis of gentamicin in complex with the methylated Kanamycin B
Classification: TRANSFERASE
Source organism: Micromonospora echinospora
Experimental method: X-RAY DIFFRACTION
Resolution: 1.932 Å
Deposited: 2016-11-28
Authors: Bury, P., Huang, F., Leadlay, P., Dias, M.V.B.
PDB entry 5u1j: Structure of pNOB8 ParA bound to nonspecific DNA
Classification: DNA BINDING PROTEIN/DNA
Source organism: Sulfolobus sp. NOB8H2; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.95 Å
Deposited: 2016-11-28
Authors: Schumacher, M.A.
PDB entry 5u1l: Crystal structure of the ATP-gated P2X7 ion channel in the closed, apo state
Classification: MEMBRANE PROTEIN
Source organism: Ailuropoda melanoleuca
Experimental method: X-RAY DIFFRACTION
Resolution: 3.4 Å
Deposited: 2016-11-28
Authors: Karasawa, A., Kawate, T.
PDB entry 5u1m: Structure of the IRS-1 PTB Domain Bound to the Juxtamembrane Region of the Insulin Receptor
Classification: PROTEIN BINDING
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2016-11-28
Authors: Eck, M.J., Dhe-Paganon, S.
PDB entry 5u1o: 2.3 Angstrom Resolution Crystal Structure of Glutathione Reductase from Vibrio parahaemolyticus in Complex with FAD.
Classification: LIPID BINDING PROTEIN
Source organism: Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.31 Å
Deposited: 2016-11-28
Authors: Minasov, G., Shuvalova, L., Cardona-Correa, A., Dubrovska, I., Grimshaw, S., Kwon, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5u1p: Crystal structure of NADP-dependent carbonyl reductase from Burkholderia multivorans in complex with NADP
Classification: OXIDOREDUCTASE
Source organism: Burkholderia multivorans (strain ATCC 17616 / 249)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2016-11-28
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5u1q: Grb7-SH2 with bicyclic peptide inhibitor
Classification: SIGNALING PROTEIN/PEPTIDE INHIBITOR
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2016-11-28
Authors: Watson, G.M., Wilce, M.C.J., Wilce, J.A.
PDB entry 5u1r: Structure of human MR1-diclofenac in complex with human MAIT A-F7 TCR
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2016-11-28
Authors: Keller, A.N., Rossjohn, J.
PDB entry 5u1s: Crystal structure of the Saccharomyces cerevisiae separase-securin complex at 3.0 angstrom resolution
Classification: HYDROLASE
Source organism: Saccharomyces cerevisiae; Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.002 Å
Deposited: 2016-11-29
Authors: Luo, S., Tong, L.
PDB entry 5u1t: Crystal structure of the Saccharomyces cerevisiae separase-securin complex at 2.6 angstrom resolution
Classification: HYDROLASE
Source organism: Saccharomyces cerevisiae; Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2016-11-29
Authors: Luo, S., Tong, L.
PDB entry 5u1u: Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist A740003
Classification: MEMBRANE PROTEIN
Source organism: Ailuropoda melanoleuca
Experimental method: X-RAY DIFFRACTION
Resolution: 3.604 Å
Deposited: 2016-11-29
Authors: Karasawa, A., Kawate, T.
PDB entry 5u1v: Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist A804598
Classification: MEMBRANE PROTEIN
Source organism: Ailuropoda melanoleuca
Experimental method: X-RAY DIFFRACTION
Resolution: 3.4 Å
Deposited: 2016-11-29
Authors: Karasawa, A., Kawate, T.
PDB entry 5u1w: Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist AZ10606120
Classification: MEMBRANE PROTEIN
Source organism: Ailuropoda melanoleuca
Experimental method: X-RAY DIFFRACTION
Resolution: 3.501 Å
Deposited: 2016-11-29
Authors: Karasawa, A., Kawate, T.
PDB entry 5u1x: Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist JNJ47965567
Classification: MEMBRANE PROTEIN
Source organism: Ailuropoda melanoleuca
Experimental method: X-RAY DIFFRACTION
Resolution: 3.201 Å
Deposited: 2016-11-29
Authors: Karasawa, A., Kawate, T.
PDB entry 5u1y: Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist GW791343
Classification: MEMBRANE PROTEIN
Source organism: Ailuropoda melanoleuca
Experimental method: X-RAY DIFFRACTION
Resolution: 3.3 Å
Deposited: 2016-11-29
Authors: Karasawa, A., Kawate, T.
PDB entry 5u1z: X-ray structure of the WlarG aminotransferase, apo form, from Campylobacter jejune
Classification: TRANSFERASE
Source organism: Campylobacter jejuni
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2016-11-29
Authors: Holden, H.M., Thoden, J.B., Dow, G.T., Gilbert, M.
PDB entry 5u20: X-ray structure of the WlaRG aminotransferase from Campylobacter jejuni, internal PLP-aldimine
Classification: TRANSFERASE
Source organism: Campylobacter jejuni
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2016-11-29
Authors: Thoden, J.B., Holden, H.M., Dow, G.T., Gilbert, M.
PDB entry 5u21: X-ray structure of the WlaRF aminotransferase from Campylobacter jejuni, K184A mutant in complex with TDP-Qui3N
Classification: TRANSFERASE
Source organism: Campylobacter jejuni
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2016-11-29
Authors: Thoden, J.B., Holden, H.M., Dow, G.T., Gilbert, M.
PDB entry 5u22: Structure of N2152 from Neocallimastix frontalis
Classification: HYDROLASE
Source organism: Neocallimastix frontalis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.748 Å
Deposited: 2016-11-29
Authors: Jones, D.R., Abbott, D.W.
PDB entry 5u23: X-ray structure of the WlaRG aminotransferase from Campylobacter jejuni in complex with TDP-Qui3N
Classification: TRANSFERASE
Source organism: Campylobacter jejuni
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2016-11-29
Authors: Holden, H.M., Thoden, J.B., Dow, G.T., Gilbert, M.
PDB entry 5u24: X-ray structure of the WlaRG aminotransferase from campylobacter jejuni, K184A mutant in complex with TDP-Fuc3N
Classification: TRANSFERASE
Source organism: Campylobacter jejuni
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2016-11-29
Authors: Holden, H.M., Thoden, J.B., Dow, G.T., Gilbert, M.
PDB entry 5u25: Crystal structure of a dihydrolipoyl dehydrogenase from Neisseria gonorrhoeae bound to FAD
Classification: OXIDOREDUCTASE
Source organism: Neisseria gonorrhoeae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2016-11-29
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5u26: Crystal Structure of Mycobacterium tuberculosis Dihydrofolate Reductase Bound to NADP and p218 Inhibitor
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2016-11-29
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5u27: Crystal Structure of Mycobacterium tuberculosis Dihydrofolate Reductase Bound to NADP and p65 Inhibitor
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2016-11-29
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5u28: BRD4 first bromodomain (BD1) in complex with dual PI3 kinase inhibitor SF2523
Classification: TRANSCRIPTION REGULATOR/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.798 Å
Deposited: 2016-11-30
Authors: Andrews, F.H., Kutateladze, T.G.
PDB entry 5u29: Crystal structure of Cryptococcus neoformans H99 Acetyl-CoA Synthetase in complex with Ac-AMS
Classification: LIGASE
Source organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2016-11-30
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID), Fox III, D., Edwards, T.E., Potts, K.T., Taylor, B.M.
PDB entry 5u2a: Crystal structure of Brucella canis Acyl-CoA Synthetase
Classification: LIGASE
Source organism: Brucella canis (strain ATCC 23365 / NCTC 10854)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2016-11-30
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID), Fox III, D., Abendroth, J.
PDB entry 5u2b: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the phenylamino-substituted estrogen, (8R,9S,13S,14S,17S)-13-methyl-17-(phenylamino)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-ol, without a coactivator peptide
Classification: TRANSCRIPTION
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.22 Å
Deposited: 2016-11-30
Authors: Nwachukwu, J.C., Nowak, J., Carlson, K.E., Katzenellenbogen, J.A., Nettles, K.W.
PDB entry 5u2c: BRD4 second bromodomain (BD2) in complex with dual PI3 kinase (PI3K) inhibitor SF2558HA
Classification: TRANSCRIPTION REGULATOR/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.3 Å
Deposited: 2016-11-30
Authors: Andrews, F.H., Kutateladze, T.G.
PDB entry 5u2d: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with Oxabicyclic Heptene Sulfonate (OBHS)
Classification: TRANSCRIPTION
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.86 Å
Deposited: 2016-11-30
Authors: Nwachukwu, J.C., Erumbi, R., Nowak, J., Carlson, K.E., Katzenellenbogen, J.A., Izard, T., Nettles, K.W.
PDB entry 5u2e: BRD4 first bromodomain (BD1) in complex with dual PI3 kinase (PI3K) inhibitor SF2535
Classification: TRANSCRIPTION REGULATOR/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.991 Å
Deposited: 2016-11-30
Authors: Andrews, F.H., Kutateladze, T.G.
PDB entry 5u2f: BRD4 first bromodomain (BD1) in complex with dual PI3 kinase (PI3K) inhibitor SF2558HA
Classification: TRANSCRIPTION REGULATOR/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.525 Å
Deposited: 2016-11-30
Authors: Andrews, F.H., Kutateladze, T.G.
PDB entry 5u2g: 2.6 Angstrom Resolution Crystal Structure of Penicillin-Binding Protein 1A from Haemophilus influenzae
Classification: LIPID BINDING PROTEIN
Source organism: Haemophilus influenzae
Experimental method: X-RAY DIFFRACTION
Resolution: 2.61 Å
Deposited: 2016-11-30
Authors: Minasov, G., Wawrzak, Z., Shuvalova, L., Kiryukhina, O., Dubrovska, I., Grimshaw, S., Kwon, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5u2h: Crystal structure of the ATP-gated P2X7 ion channel bound to ATP and allosteric antagonist A804598
Classification: MEMBRANE PROTEIN
Source organism: Ailuropoda melanoleuca
Experimental method: X-RAY DIFFRACTION
Resolution: 3.903 Å
Deposited: 2016-11-30
Authors: Karasawa, A., Kawate, T.
PDB entry 5u2i: Crystal structure of a nucleoside diphosphate kinase from Naegleria fowleri
Classification: TRANSFERASE
Source organism: Naegleria fowleri
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2016-11-30
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 5u2j: MORF double PHD finger (DPF) in complex with histone H3K14bu
Classification: HYDROLASE
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2016-11-30
Authors: Andrews, F.H., Klein, B.J., Kutateladze, T.G.
PDB entry 5u2k: Crystal structure of Galactoside O-acetyltransferase complex with CoA (H3 space group)
Classification: TRANSFERASE
Source organism: Staphylococcus aureus (strain COL)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.38 Å
Deposited: 2016-11-30
Authors: Czub, M.P., Porebski, P.J., Knapik, A.A., Niedzialkowska, E., Siuda, M.K., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 5u2l: Crystal structure of the Hsp104 N-terminal domain from Candida albicans
Classification: PROTEIN BINDING
Source organism: Candida albicans (strain SC5314 / ATCC MYA-2876)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6555 Å
Deposited: 2016-11-30
Authors: Wang, P., Li, J., Sha, B.
PDB entry 5u2m: Crystal structure of human NAMPT with A-1293201
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.89 Å
Deposited: 2016-11-30
Authors: Longenecker, K.L., Raich, D., Korepanova, A.V.
PDB entry 5u2n: Crystal structure of human NAMPT with A-1326133
Classification: Transferase/Transferase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.73 Å
Deposited: 2016-11-30
Authors: Longenecker, K.L., Raich, D., Korepanova, A.V.
PDB entry 5u2o: Crystal structure of Zn-binding triple mutant of GH family 9 endoglucanase J30
Classification: HYDROLASE
Source organism: Thermobacillus composti KWC4
Experimental method: X-RAY DIFFRACTION
Resolution: 1.46 Å
Deposited: 2016-11-30
Authors: Ellinghaus, T.L., Pereira, J.H., McAndrew, R.P., Welner, D.H., Adams, P.D.
PDB entry 5u2p: The crystal structure of Tp0737 from Treponema pallidum
Classification: TRANSPORT PROTEIN
Source organism: Treponema pallidum subsp. pallidum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.76 Å
Deposited: 2016-11-30
Authors: Brautigam, C.A., Deka, R.K., Tomchick, D.R., Norgard, M.V.
PDB entry 5u2r: PRECATALYTIC TERNARY COMPLEX OF HUMAN DNA POLYMERASE BETA WITH GAPPED DNA SUBSTARTE, INCOMING L-DCTP AND CA2+
Classification: TRANSFERASE/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2016-11-30
Authors: Vyas, R., Suo, Z.
PDB entry 5u2s: Pre-catalytic ternary complex of Human DNA Polymerase Beta With Gapped DNA substrate incoming (-)3TC-TP and Ca2+.
Classification: TRANSFERASE/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2016-11-30
Authors: Vyas, R., Suo, Z.