LiteFold/PDB huggingface dataset:
PDB entry 4ztz: Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase
Classification: DNA Binding Protein/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.442 Å
Deposited: 2015-05-15
Authors: Szymanski, M.R., Yin, Y.W.
PDB entry 4zu0: Structure of the complex of type 1 ribosome inactivating protein from Momordica balsamina with a nucleotide, cytidine monophosphate at 1.80 A resolution
Classification: HYDROLASE
Source organism: Momordica balsamina
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2015-05-15
Authors: Yamin, S., Pandey, S., Kaur, P., Sharma, S., Singh, T.P.
PDB entry 4zu1: Crystal Structure of O-Acetylserine Sulfhydrylase from Haemophilus influenzae in complex with O-acetyl serine and peptide inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Haemophilus influenzae KW20; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.202 Å
Deposited: 2015-05-15
Authors: Ekka, M.K., Singh, A.K., Kaushik, A., Kumaran, S.
PDB entry 4zu2: Pseudomonas aeruginosa AtuE
Classification: HYDROLASE
Source organism: Pseudomonas aeruginosa
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2015-05-15
Authors: Poudel, N., Pfannstiel, J., Simon, O., Walter, N., Jendrossek, D., Papageorgiou, A.C.
PDB entry 4zu3: Halohydrin hydrogen-halide-lyases, HheB
Classification: LYASE
Source organism: Corynebacterium sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2015-05-15
Authors: Watanabe, F., Yu, F., Ohtaki, A., Yamanaka, Y., Noguchi, K., Yohda, M., Odaka, M.
PDB entry 4zu4: X-ray structure of the 3,4-ketoisomerase domain of FdtD from Shewanella denitrificans
Classification: ISOMERASE
Source organism: Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2015-05-15
Authors: Thoden, J.B., Vinogradov, E., Gilbert, M., Salinger, A.J., Holden, H.M.
PDB entry 4zu5: Crystal structure of the QdtA 3,4-Ketoisomerase from Thermoanaerobacterium thermosaccharolyticum, apo form
Classification: ISOMERASE
Source organism: Thermoanaerobacterium thermosaccharolyticum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2015-05-15
Authors: Thoden, J.B., Vinogradov, E., Gilbert, M., Salinger, A.J., Holden, H.M.
PDB entry 4zu6: Crystal Structure of O-Acetylserine Sulfhydrylase from Haemophilus influenzae in complex with pre-reactive o-acetyl serine, alpha-aminoacrylate reaction intermediate and Peptide inhibitor at the resolution of 2.25A
Classification: Transferase/Transferase Inhibitor
Source organism: Haemophilus influenzae KW20; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.03 Å
Deposited: 2015-05-15
Authors: Ekka, M.K., Singh, A.K., Kaushik, A., Kumaran, S.
PDB entry 4zu7: X-ray structure if the QdtA 3,4-ketoisomerase from Thermoanaerobacterium thermosaccharolyticum, double mutant Y17R/R97H, in complex with TDP
Classification: ISOMERASE
Source organism: Thermoanaerobacterium thermosaccharolyticum
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2015-05-15
Authors: Thoden, J.B., Vinogradov, E., Gilbert, M., Salinger, A.J., Holden, H.M.
PDB entry 4zu9: Crystal structure of bacterial selenocysteine-specific elongation factor EF-Sec
Classification: TRANSLATION
Source organism: Aquifex aeolicus VF5
Experimental method: X-RAY DIFFRACTION
Resolution: 3.191 Å
Deposited: 2015-05-15
Authors: Itoh, Y., Sekine, S., Yokoyama, S.
PDB entry 4zua: Crystal structure of the ExsA regulatory domain
Classification: TRANSCRIPTION
Source organism: Pseudomonas aeruginosa PAO1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2015-05-15
Authors: Schubot, F.D.
PDB entry 4zud: Crystal Structure of Human Angiotensin Receptor in Complex with Inverse Agonist Olmesartan at 2.8A resolution.
Classification: MEMBRANE PROTEIN
Source organism: Escherichia coli; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2015-05-15
Authors: Zhang, H., Unal, H., Desnoyer, R., Han, G.W., Patel, N., Katritch, V., Karnik, S.S., Cherezov, V., Stevens, R.C., GPCR Network (GPCR)
PDB entry 4zuh: Complex structure of PEDV 3CLpro mutant (C144A) with a peptide substrate.
Classification: HYDROLASE/PEPTIDE
Source organism: Porcine epidemic diarrhea virus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.394 Å
Deposited: 2015-05-16
Authors: Ye, G., Fu, Z.F., Peng, G.Q.
PDB entry 4zui: Crystal structure of Staphylococcal nuclease variant Delta+PHS V23H at cryogenic temperature
Classification: HYDROLASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2015-05-16
Authors: Sorenson, J.L., Schlessman, J.L., Garcia-Moreno E., B.
PDB entry 4zuj: Crystal structure of Staphylococcal nuclease variant Delta+PHS Y91H at cryogenic temperature
Classification: HYDROLASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.72 Å
Deposited: 2015-05-16
Authors: Sorenson, J.L., Schlessman, J.L., Garcia-Moreno E., B.
PDB entry 4zuk: Structure ALDH7A1 complexed with NAD+
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.001 Å
Deposited: 2015-05-16
Authors: Luo, M., Tanner, J.J.
PDB entry 4zul: Structure ALDH7A1 complexed with alpha-aminoadipate
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.76 Å
Deposited: 2015-05-16
Authors: Luo, M., Tanner, J.J.
PDB entry 4zum: Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a trifluoromethylketone inhibitor
Classification: Hydrolase/Hydrolase inhibitor
Source organism: Mycoplana ramosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.42 Å
Deposited: 2015-05-17
Authors: Decroos, C., Christianson, D.W.
PDB entry 4zun: Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a thiol inhibitor
Classification: Hydrolase/Hydrolase inhibitor
Source organism: Mycoplana ramosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2015-05-17
Authors: Decroos, C., Christianson, D.W.
PDB entry 4zuo: Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a hydroxamate inhibitor
Classification: Hydrolase/Hydrolase inhibitor
Source organism: Mycoplana ramosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.33 Å
Deposited: 2015-05-17
Authors: Decroos, C., Christianson, D.W.
PDB entry 4zup: Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a hydroxamate inhibitor
Classification: Hydrolase/Hydrolase inhibitor
Source organism: Mycoplana ramosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.421 Å
Deposited: 2015-05-17
Authors: Decroos, C., Christianson, D.W.
PDB entry 4zuq: Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a hydroxamate inhibitor
Classification: Hydrolase/Hydrolase inhibitor
Source organism: Mycoplana ramosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.22 Å
Deposited: 2015-05-17
Authors: Decroos, C., Christianson, D.W.
PDB entry 4zur: Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a hydroxamate inhibitor
Classification: Hydrolase/Hydrolase inhibitor
Source organism: Mycoplana ramosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.13 Å
Deposited: 2015-05-17
Authors: Decroos, C., Christianson, D.W.
PDB entry 4zus: Crystal structure of Equine MHC I(Eqca-N*00602) in complexed with equine infectious anaemia virus (EIAV) derived peptide REV-QW11
Classification: IMMUNE SYSTEM
Source organism: Equus caballus; Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-05-17
Authors: Yao, S., Liu, J., Qi, J., Chen, R., Zhang, N., Liu, Y., Xia, C.
PDB entry 4zut: Crystal structure of Equine MHC I(Eqca-N*00602) in complexed with equine infectious anaemia virus (EIAV) derived peptide Gag-GW12
Classification: IMMUNE SYSTEM
Source organism: Equus caballus; Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-05-17
Authors: Yao, S., Liu, J., Qi, J., Chen, R., Zhang, N., Liu, Y., Xia, C.
PDB entry 4zuu: Crystal structure of Equine MHC I(Eqca-N*00602) in complexed with equine infectious anaemia virus (EIAV) derived peptide Gag-CF9
Classification: IMMUNE SYSTEM
Source organism: Equus caballus; Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2015-05-17
Authors: Yao, S., Liu, J., Qi, J., Chen, R., Zhang, N., Liu, Y., Xia, C.
PDB entry 4zuv: Crystal structure of Equine MHC I(Eqca-N*00602) in complexed with equine infectious anaemia virus (EIAV) derived peptide Env-RW12
Classification: IMMUNE SYSTEM
Source organism: Equus caballus; Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2015-05-17
Authors: Yao, S., Liu, J., Qi, J., Chen, R., Zhang, N., Liu, Y., Xia, C.
PDB entry 4zuw: Crystal structure of Equine MHC I(Eqca-N*00601) in complexed with equine infectious anaemia virus (EIAV) derived peptide Gag-GW12
Classification: IMMUNE SYSTEM
Source organism: Equus caballus; Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-05-17
Authors: Yao, S., Liu, J., Qi, J., Chen, R., Zhang, N., Liu, Y., Xia, C.
PDB entry 4zux: SAGA DUB module Ubp8/Sgf11/Sus1/Sgf73 bound to ubiqitinated nucleosome
Classification: Hydrolase/DNA
Source organism: Homo sapiens; Saccharomyces cerevisiae (strain ATCC 204508 / S288c); Saccharomyces cerevisiae (strain YJM789); synthetic construct; Xenopus laevis
Experimental method: X-RAY DIFFRACTION
Resolution: 3.82 Å
Deposited: 2015-05-17
Authors: Morgan, M., Wolberger, C.
PDB entry 4zuy: Structure of Tsi6 from Pseudomonas aeruginosa
Classification: PROTEIN BINDING
Source organism: Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.952 Å
Deposited: 2015-05-18
Authors: Whitney, J.C., Sawai, S., Robinson, H., Mougous, J.D.
PDB entry 4zuz: SidC 1-871
Classification: Phosphate Binding Protein
Source organism: Legionella pneumophila
Experimental method: X-RAY DIFFRACTION
Resolution: 2.86 Å
Deposited: 2015-05-18
Authors: Luo, X., Wasilko, D.J., Liu, Y., Sun, J., Wu, X., Luo, Z.-Q., Mao, Y.
PDB entry 4zv0: Structure of Tse6 in complex with Tsi6
Classification: PROTEIN BINDING
Source organism: Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.401 Å
Deposited: 2015-05-18
Authors: Whitney, J.C., Sawai, S., Ralston, C., Mougous, J.D.
PDB entry 4zv1: An ancestral arginine-binding protein bound to arginine
Classification: SOLUTE-BINDING PROTEIN
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 1.52 Å
Deposited: 2015-05-18
Authors: Clifton, B.E., Carr, P.D., Jackson, C.J.
PDB entry 4zv2: An ancestral arginine-binding protein bound to glutamine
Classification: SOLUTE-BINDING PROTEIN
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 1.43 Å
Deposited: 2015-05-18
Authors: Clifton, B.E., Jackson, C.J.
PDB entry 4zv3: Crystal structure of the N- and C-terminal domains of mouse acyl-CoA thioesterase 7
Classification: HYDROLASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1 Å
Deposited: 2015-05-18
Authors: Swarbrick, C.M.D., Forwood, J.K.
PDB entry 4zv4: Structure of Tse6 in complex with EF-Tu
Classification: TRANSLATION
Source organism: Pseudomonas aeruginosa; Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.504 Å
Deposited: 2015-05-18
Authors: Whitney, J.C., Sawai, S., Robinson, H., Mougous, J.D.
PDB entry 4zv5: Crystal structure of N-myristoylated mouse mammary tumor virus matrix protein
Classification: VIRAL PROTEIN
Source organism: Mouse mammary tumor virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.57 Å
Deposited: 2015-05-18
Authors: Zabransky, A., Dolezal, M., Dostal, J., Vanek, O., Hadravova, R., Stokrova, J., Brynda, J., Pichova, I.
PDB entry 4zv6: Crystal structure of the artificial alpharep-7 octarellinV.1 complex
Classification: DE NOVO PROTEIN
Source organism: synthetic construct
Experimental method: X-RAY DIFFRACTION
Resolution: 2.22 Å
Deposited: 2015-05-18
Authors: Figueroa, M., Sleutel, M., Urvoas, A., Valerio-Lepiniec, M., Minard, P., Martial, J.A., van de Weerdt, C.
PDB entry 4zv7: Crystal structure of hexagonal form of lipase B from Candida antarctica
Classification: HYDROLASE
Source organism: Candida antarctica
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-05-18
Authors: Strzelczyk, P., Blaszczyk, J., Bujacz, G.
PDB entry 4zv8: Structure of CYP2B6 (Y226H/K262R) with additional mutation Y244W in complex with alpha-Pinene
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.24 Å
Deposited: 2015-05-18
Authors: Liu, J., Shah, M.B., Stout, C.D., Halpert, J.R.
PDB entry 4zv9: 2.00 Angstrom resolution crystal structure of an uncharacterized protein from Escherichia coli O157:H7 str. Sakai
Classification: Structural Genomics, Unknown Function
Source organism: Escherichia coli O157:H7
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-05-18
Authors: Halavaty, A.S., Wawrzak, Z., Filippova, E.V., Kiryukhina, O., Endres, M., Joachimiak, A., Anderson, W.F., Midwest Center for Structural Genomics (MCSG)
PDB entry 4zva: Crystal structure of globin domain of the E. coli DosC - form I (ferric)
Classification: SIGNALING PROTEIN
Source organism: Escherichia coli (strain K12)
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-05-18
Authors: Tarnawski, M., Barends, T.R.M., Schlichting, I.
PDB entry 4zvb: Crystal structure of globin domain of the E. coli DosC - form II (ferrous)
Classification: SIGNALING PROTEIN
Source organism: Escherichia coli (strain K12)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2015-05-18
Authors: Tarnawski, M., Barends, T.R.M., Schlichting, I.
PDB entry 4zvc: Crystal structure of MID domain of the E. coli DosC - form I
Classification: SIGNALING PROTEIN
Source organism: Escherichia coli K-12
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2015-05-18
Authors: Tarnawski, M., Barends, T.R.M., Schlichting, I.
PDB entry 4zvd: Crystal structure of MID domain of the E. coli DosC - form II
Classification: SIGNALING PROTEIN
Source organism: Escherichia coli K-12
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2015-05-18
Authors: Tarnawski, M., Barends, T.R.M., Schlichting, I.
PDB entry 4zve: Crystal structure of GGDEF domain of the E. coli DosC - form I (apo-form)
Classification: SIGNALING PROTEIN
Source organism: Escherichia coli K-12
Experimental method: X-RAY DIFFRACTION
Resolution: 1.2 Å
Deposited: 2015-05-18
Authors: Tarnawski, M., Barends, T.R.M., Schlichting, I.
PDB entry 4zvf: Crystal structure of GGDEF domain of the E. coli DosC - form II (GTP-alpha-S-bound)
Classification: SIGNALING PROTEIN
Source organism: Escherichia coli K-12
Experimental method: X-RAY DIFFRACTION
Resolution: 1.15 Å
Deposited: 2015-05-18
Authors: Tarnawski, M., Barends, T.R.M., Schlichting, I.
PDB entry 4zvg: Crystal structure of GGDEF domain of the E. coli DosC - form III
Classification: SIGNALING PROTEIN
Source organism: Escherichia coli K-12
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2015-05-18
Authors: Tarnawski, M., Barends, T.R.M., Schlichting, I.
PDB entry 4zvh: Crystal structure of GGDEF domain of the E. coli DosC - form IV
Classification: SIGNALING PROTEIN
Source organism: Escherichia coli K-12
Experimental method: X-RAY DIFFRACTION
Resolution: 3.301 Å
Deposited: 2015-05-18
Authors: Tarnawski, M., Barends, T.R.M., Schlichting, I.
PDB entry 4zvi: GYRASE B IN COMPLEX WITH 4,5-DIBROMOPYRROLAMIDE-BASED INHIBITOR
Classification: ISOMERASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2015-05-18
Authors: Zidar, N., Macut, H., Tomasic, T., Brvar, M., Montalvao, S., Tammela, P., Solmajer, T., Peterlin Masic, L., Ilas, J., Kikelj, D.
PDB entry 4zvj: Structure of human triose phosphate isomerase K13M
Classification: ISOMERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6996 Å
Deposited: 2015-05-18
Authors: Amrich, C.G., Smith, C., Heroux, A., VanDemark, A.P.
PDB entry 4zvk: Reduced quinone reductase 2 in complex with ethidium
Classification: Oxidoreductase/oxidoreductase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.867 Å
Deposited: 2015-05-18
Authors: Leung, K.K., Shilton, B.H.
PDB entry 4zvl: Oxidized quinone reductase 2 in complex with acridine orange
Classification: Oxidoreductase/Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.899 Å
Deposited: 2015-05-18
Authors: Leung, K.K., Shilton, B.H.
PDB entry 4zvm: Oxidized quinone reductase 2 in complex with doxorubicin
Classification: oxidoreductase/oxidoreductase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.973 Å
Deposited: 2015-05-18
Authors: Leung, K.K., Shilton, B.H.
PDB entry 4zvn: Reduced quinone reductase 2 in complex with acridine orange
Classification: Oxidoreductase/oxidoreductase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.866 Å
Deposited: 2015-05-18
Authors: Leung, K.K., Shilton, B.H.
PDB entry 4zvo: Caspase-7 Variant 4 (V4) with reprogrammed substrate specificity due to Y230V/W232Y/S234V/Q276D substitutions bound to VEID inhibitor.
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.85 Å
Deposited: 2015-05-18
Authors: Hill, M.E., MacPherson, D.J., Hardy, J.A.
PDB entry 4zvp: Caspase-7 Variant 2 (V2) with reprogrammed substrate specificity due to Y230V/W232M/Q276C substitutions bound to DEVD inhibitor.
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2015-05-18
Authors: Hill, M.E., MacPherson, D.J., Hardy, J.A.
PDB entry 4zvq: Caspase-7 Variant 2 (V2) with reprogrammed substrate specificity due to Y230V/W232M/Q276C substitutions bound to VEID inhibitor.
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2015-05-18
Authors: Hill, M.E., MacPherson, D.J., Hardy, J.A.
PDB entry 4zvr: Caspase-7 Variant 4 (V4) with reprogrammed substrate specificity due to Y230V/W232Y/S234V/Q276D substitutions bound to DEVD inhibitor.
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2015-05-18
Authors: Hill, M.E., MacPherson, D.J., Hardy, J.A.
PDB entry 4zvs: Caspase-7 Variant 1 (V1) with reprogrammed substrate specificity due to Y230A/W232M/S234N substitutions, bound to DEVD inhibitor.
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2015-05-18
Authors: MacPherson, D.J., Hill, M.E., Hardy, J.A.
PDB entry 4zvt: Caspase-7 Variant 1 (V1) with reprogrammed substrate specificity due to Y230A/W232M/S234N substitutions, bound to VEID inhibitor.
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.85 Å
Deposited: 2015-05-18
Authors: Hardy, J.A., MacPherson, D.J., Hill, M.E.
PDB entry 4zvu: Caspase-7 wild-type bound to the caspase-6 cognate tetrapeptide inhibitor Ac-VEID-cho
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.601 Å
Deposited: 2015-05-18
Authors: Hardy, J.A., MacPherson, D.J., Hill, M.E.
PDB entry 4zvv: Lactate dehydrogenase A in complex with a trisubstituted piperidine-2,4-dione inhibitor GNE-140
Classification: Oxidoreductase/Oxidoreductase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2015-05-18
Authors: Li, Y., Chen, Z., Eigenbrot, C.
PDB entry 4zvw: Structure of apo human ALDH7A1 in space group C2
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2015-05-18
Authors: Tanner, J.J.
PDB entry 4zvx: Structure of apo human ALDH7A1 in space group P4212
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2015-05-18
Authors: Tanner, J.J.
PDB entry 4zvy: Structure of human ALDH7A1 complexed with NAD+ in space group P4212
Classification: OXIDOREDUCTASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2015-05-18
Authors: Tanner, J.J.
PDB entry 4zvz: Co-crystal structures of PP5 in complex with 5-methyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-05-18
Authors: Chattopadhyay, D., Swingle, M.R., Salter, E.A., Wierzbicki, A., Honkanen, R.E.
PDB entry 4zw0: Crystal structure of beta-Hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Candidatus asiaticum
Classification: LYASE
Source organism: Liberibacter asiaticus (strain psy62)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2015-05-19
Authors: Wang, S., Gao, Z., Jiang, L., Dong, Y.H.
PDB entry 4zw1: Crystal structure of hBRD4 in complex with BL-BI06 reveals a novel synthesized inhibitor that induces Beclin1-independent/ATG5-dependent autophagic cell death in breast cancer
Classification: TRANSCRIPTION/INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2015-05-19
Authors: Liu, B., Zhang, S., Guo, M., Tian, M.
PDB entry 4zw2: Crystal structure of the Mouse voltage gated calcium channel beta subunit isoform 1a in complex with Alpha Interaction Domain peptide.
Classification: METAL TRANSPORT
Source organism: Mus musculus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.86 Å
Deposited: 2015-05-19
Authors: Norris, N.C., Oakley, A.J.
PDB entry 4zw3: X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9b
Classification: HYDROLASE/HYDROLASE inhibitor
Source organism: Plasmodium falciparum (isolate FcB1 / Columbia)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2015-05-19
Authors: Drinkwater, N., McGowan, S.
PDB entry 4zw5: X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9f
Classification: HYDROLASE/HYDROLASE inhibitor
Source organism: Plasmodium falciparum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2015-05-19
Authors: Drinkwater, N., McGowan, S.
PDB entry 4zw6: X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9q
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Plasmodium falciparum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2015-05-19
Authors: Drinkwater, N., McGowan, S.
PDB entry 4zw7: X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9m
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Plasmodium falciparum (isolate FcB1 / Columbia)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2015-05-19
Authors: Drinkwater, N., McGowan, S.
PDB entry 4zw8: X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9r
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Plasmodium falciparum
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-05-19
Authors: Drinkwater, N., McGowan, S.
PDB entry 4zw9: Crystal structure of human GLUT3 bound to D-glucose in the outward-occluded conformation at 1.5 angstrom
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.502 Å
Deposited: 2015-05-19
Authors: Deng, D., Sun, P.C., Yan, C.Y., Yan, N.
PDB entry 4zwb: Crystal structure of maltose-bound human GLUT3 in the outward-occluded conformation at 2.4 angstrom
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2015-05-19
Authors: Deng, D., Sun, P.C., Yan, C.Y., Yan, N.
PDB entry 4zwc: Crystal structure of maltose-bound human GLUT3 in the outward-open conformation at 2.6 angstrom
Classification: TRANSPORT PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-05-19
Authors: Deng, D., Sun, P.C., Yan, C.Y., Yan, N.
PDB entry 4zwe: Crystal structure of the dGTP-bound catalytic core of SAMHD1 T592V mutant
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.81 Å
Deposited: 2015-05-19
Authors: Tang, C., Ji, X., Xiong, Y.
PDB entry 4zwg: Crystal structure of the GTP-dATP-bound catalytic core of SAMHD1 phosphomimetic T592E mutant
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2015-05-19
Authors: Tang, C., Ji, X., Xiong, Y.
PDB entry 4zwi: Surface Lysine Acetylated Human Carbonic Anhydrase II in Complex with a Sulfamate-Based Inhibitor
Classification: Lyase/Lyase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2015-05-19
Authors: Lomelino, C.L., Mahon, B.P., McKenna, M.
PDB entry 4zwj: Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
Classification: SIGNALING PROTEIN
Source organism: Enterobacteria phage T4; Homo sapiens; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.302 Å
Deposited: 2015-05-19
Authors: Kang, Y., Zhou, X.E., Gao, X., He, Y., Liu, W., Ishchenko, A., Barty, A., White, T.A., Yefanov, O., Han, G.W., Xu, Q., de Waal, P.W., Ke, J., Tan, M.H.E., Zhang, C., Moeller, A., West, G.M., Pascal, B., Eps, N.V., Caro, L.N., Vishnivetskiy, S.A., Lee, R.J., Suino-Powell, K.M., Gu, X., Pal, K., Ma, J., Zhi, X., Boutet, S., Williams, G.J., Messerschmidt, M., Gati, C., Zatsepin, N.A., Wang, D., James, D., Basu, S., Roy-Chowdhury, S., Conrad, C., Coe, J., Liu, H., Lisova, S., Kupitz, C., Grotjohann, I., Fromme, R., Jiang, Y., Tan, M., Yang, H., Li, J., Wang, M., Zheng, Z., Li, D., Howe, N., Zhao, Y., Standfuss, J., Diederichs, K., Dong, Y., Potter, C.S., Carragher, B., Caffrey, M., Jiang, H., Chapman, H.N., Spence, J.C.H., Fromme, P., Weierstall, U., Ernst, O.P., Katritch, V., Gurevich, V.V., Griffin, P.R., Hubbell, W.L., Stevens, R.C., Cherezov, V., Melcher, K., Xu, H.E., GPCR Network (GPCR)
PDB entry 4zwl: 2.60 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) H448F/Y450L double mutant from Staphylococcus aureus in complex with NAD+ and BME-free Cys289
Classification: OXIDOREDUCTASE
Source organism: Staphylococcus aureus (strain COL)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-05-19
Authors: Halavaty, A.S., Minasov, G., Chen, C., Joo, J.C., Yakunin, A.F., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4zwm: 2.3 A resolution crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49
Classification: TRANSFERASE
Source organism: Toxoplasma gondii ME49
Experimental method: X-RAY DIFFRACTION
Resolution: 2.31 Å
Deposited: 2015-05-19
Authors: Filippova, E.V., Minasov, G., Flores, K., Van Le, H., Silverman, R.B., McLeod, R., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4zwn: Crystal Structure of a Soluble Variant of the Monoglyceride Lipase from Saccharomyces Cerevisiae
Classification: HYDROLASE
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.491 Å
Deposited: 2015-05-19
Authors: Aschauer, P., Rengachari, S., Gruber, K., Oberer, M.
PDB entry 4zwo: Crystal structure of organophosphate anhydrolase/prolidase mutant Y212F
Classification: HYDROLASE
Source organism: Alteromonas sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2.141 Å
Deposited: 2015-05-19
Authors: Daczkowski, C.M., Pegan, S.D., Harvey, S.P.
PDB entry 4zwp: Crystal structure of organophosphate anhydrolase/prolidase mutant Y212F
Classification: HYDROLASE
Source organism: Alteromonas sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2.397 Å
Deposited: 2015-05-19
Authors: Daczkowski, C.M., Pegan, S.D., Harvey, S.P.
PDB entry 4zwq: Crystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice Type I
Classification: VIRAL PROTEIN
Source organism: Enterobacteria phage T4
Experimental method: X-RAY DIFFRACTION
Resolution: 2.351 Å
Deposited: 2015-05-19
Authors: Gajewski, S., White, S.W.
PDB entry 4zwr: Crystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice Type II
Classification: VIRAL PROTEIN
Source organism: Enterobacteria phage T4
Experimental method: X-RAY DIFFRACTION
Resolution: 3.3857 Å
Deposited: 2015-05-19
Authors: Gajewski, S., White, S.W.
PDB entry 4zws: Crystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice Type III
Classification: VIRAL PROTEIN
Source organism: Enterobacteria phage T4
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-05-19
Authors: Gajewski, S., White, S.W.
PDB entry 4zwt: Crystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice Type IV
Classification: VIRAL PROTEIN
Source organism: Enterobacteria phage T4
Experimental method: X-RAY DIFFRACTION
Resolution: 4.2 Å
Deposited: 2015-05-19
Authors: Gajewski, S., White, S.W.
PDB entry 4zwu: Crystal structure of organophosphate anhydrolase/prolidase mutant Y212F, V342L, I215Y
Classification: HYDROLASE
Source organism: Alteromonas sp.
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2015-05-19
Authors: Daczkowski, C.M., Pegan, S.D., Harvey, S.P.
PDB entry 4zwv: Crystal Structure of Aminotransferase AtmS13 from Actinomadura melliaura
Classification: TRANSFERASE
Source organism: Actinomadura melliaura
Experimental method: X-RAY DIFFRACTION
Resolution: 1.503 Å
Deposited: 2015-05-19
Authors: Kim, Y., Bigelow, L., Endres, M., Wang, F., Phillips Jr., G.N., Joachimiak, A., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
PDB entry 4zwx: Engineered Carbonic Anhydrase IX mimic in complex with glucosyl sulfamate inhibitor
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.696 Å
Deposited: 2015-05-19
Authors: Mahon, B.P., Lomelino, C.L., Salguero, A.L., McKenna, R.
PDB entry 4zwy: Human Carbonic Anhydrase II in complex with a glucosyl sulfamate inhibitor
Classification: Lyase/Lyase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2015-05-19
Authors: Mahon, B.P., Lomelino, C.L., Driscoll, J.M., McKenna, R.
PDB entry 4zwz: Engineered Carbonic Anhydrase IX mimic in complex with a glucosyl sulfamate inhibitor
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.62 Å
Deposited: 2015-05-19
Authors: Mahon, B.P., Lomelino, C.L., Driscoll, J.M., McKenna, R.
PDB entry 4zx0: Human Carbonic Anhydrase II in complex with a glucosyl sulfamate inhibitor
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2015-05-19
Authors: Mahon, B.P., Lomelino, C.L., Pinard, M.A., McKenna, R.
PDB entry 4zx1: Engineered Carbonic Anhydrase IX mimic in complex with a glucosyl sulfamate inhibitor
Classification: LYASE/LYASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.501 Å
Deposited: 2015-05-20
Authors: Mahon, B.P., Lomelino, C.L., Salguero, A.L., McKenna, R.
PDB entry 4zx2: Co-crystal structures of PP5 in complex with 5-methyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.23 Å
Deposited: 2015-05-19
Authors: Chattopadhyay, D., Swingle, M.R., Salter, E.A., Wierzbicki, A., Honkanen, R.E.
PDB entry 4zx3: X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 10b
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Plasmodium falciparum
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-05-20
Authors: Drinkwater, N., McGowan, S.
PDB entry 4zx4: X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 10o
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Plasmodium falciparum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2015-05-20
Authors: Drinkwater, N., McGowan, S.
PDB entry 4zx5: X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 10q
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Plasmodium falciparum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2015-05-20
Authors: Drinkwater, N., McGowan, S.
PDB entry 4zx6: X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 10s
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Plasmodium falciparum (isolate FcB1 / Columbia)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.05 Å
Deposited: 2015-05-20
Authors: Drinkwater, N., McGowan, S.
PDB entry 4zx8: X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 9b
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Plasmodium falciparum FcB1/Columbia
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2015-05-20
Authors: Drinkwater, N., McGowan, S.
PDB entry 4zx9: X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10b
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Plasmodium falciparum FcB1/Columbia
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-05-20
Authors: Drinkwater, N., McGowan, S.
PDB entry 4zxa: Crystal Structure of hydroquinone 1,2-dioxygenase PnpCD in complex with Cd2+ and 4-hydroxybenzonitrile
Classification: OXIDOREDUCTASE
Source organism: Pseudomonas sp. (strain WBC-3)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.488 Å
Deposited: 2015-05-20
Authors: Liu, S., Su, T., Zhang, C., Gu, L.
PDB entry 4zxb: Structure of the human insulin receptor ectodomain, IRDeltabeta construct, in complex with four Fab molecules
Classification: HORMONE RECEPTOR/IMMUNE SYSTEM
Source organism: Homo sapiens; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 3.3 Å
Deposited: 2015-05-20
Authors: Croll, T., Smith, B.J., Margetts, M.B., Whittaker, J., Weiss, M.A., Ward, C.W., Lawrence, M.C.
PDB entry 4zxc: Crystal Structure of hydroquinone 1,2-dioxygenase PnpCD in complex with Fe3+
Classification: OXIDOREDUCTASE
Source organism: Pseudomonas sp. (strain WBC-3)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.05 Å
Deposited: 2015-05-20
Authors: Liu, S., Su, T., Zhang, C., Gu, L.
PDB entry 4zxd: Crystal Structure of hydroquinone 1,2-dioxygenase PnpCD
Classification: OXIDOREDUCTASE
Source organism: Pseudomonas sp. (strain WBC-3)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.052 Å
Deposited: 2015-05-20
Authors: Liu, S., Su, T., Zhang, C., Gu, L.
PDB entry 4zxe: X-ray crystal structure of chitosan-binding module 1 derived from chitosanase/glucanase from Paenibacillus sp. IK-5.
Classification: HYDROLASE
Source organism: Paenibacillus fukuinensis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2015-05-20
Authors: Shinya, S., Oi, H., Kitaoku, Y., Ohnuma, T., Numata, T., Fukamizo, T.
PDB entry 4zxf: Crystal Structure of a Soluble Variant of Monoglyceride Lipase from Saccharomyces Cerevisiae in Complex with a Substrate Analog
Classification: HYDROLASE
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2015-05-20
Authors: Aschauer, P., Lichtenegger, J., Rengachari, S., Gruber, K., Oberer, M.
PDB entry 4zxg: Ligandin binding site of PfGST
Classification: TRANSFERASE
Source organism: Plasmodium falciparum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2015-05-20
Authors: Perbandt, M., Eberle, R., Betzel, C.
PDB entry 4zxh: Crystal Structure of holo-AB3403 a four domain nonribosomal peptide synthetase from Acinetobacter Baumanii
Classification: BIOSYNTHETIC PROTEIN
Source organism: Acinetobacter baumannii (strain AB307-0294)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2015-05-20
Authors: Drake, E.J., Miller, B.R., Allen, C.L., Gulick, A.M.
PDB entry 4zxi: Crystal Structure of holo-AB3403 a four domain nonribosomal peptide synthetase bound to AMP and Glycine
Classification: BIOSYNTHETIC PROTEIN
Source organism: Acinetobacter baumannii (strain AB307-0294)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.9 Å
Deposited: 2015-05-20
Authors: Drake, E.J., Miller, B.R., Allen, C.L., Gulick, A.M.
PDB entry 4zxk: Carbohydrate binding domain from Streptococcus pneumoniae NanA sialidase
Classification: SUGAR BINDING PROTEIN
Source organism: Streptococcus pneumoniae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.84 Å
Deposited: 2015-05-20
Authors: Yang, L., Connaris, H., Potter, J.A., Taylor, G.L.
PDB entry 4zxl: CpOGA D298N in complex with Drosophila HCF -derived Thr-O-GlcNAc peptide
Classification: HYDROLASE/PEPTIDE
Source organism: Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-05-20
Authors: Selvan, N., van Aalten, D.M.F.
PDB entry 4zxm: Crystal structure of PGRP domain from Branchiostoma belcheri tsingtauense peptidoglycan recognition protein 3
Classification: HYDROLASE
Source organism: Branchiostoma belcheri tsingtauense
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2015-05-20
Authors: Wang, W.J., Cheng, W., Jiang, Y.L., Yu, H.M., Luo, M.
PDB entry 4zxn: Crystal structure of rat coronavirus strain New-Jersey Hemagglutinin-Esterase
Classification: VIRAL PROTEIN
Source organism: Rat coronavirus (strain NJ)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2015-05-20
Authors: Bakkers, M.J.G., Feitsma, L.J., Huizinga, E.G., de Groot, R.J.
PDB entry 4zxo: The structure of a GH26 beta-mannanase from Bacteroides ovatus, BoMan26A.
Classification: HYDROLASE
Source organism: Bacteroides ovatus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2015-05-20
Authors: Bagenholm, V., Aurelius, O., Logan, D.T., Bouraoui, H., Stalbrand, H.
PDB entry 4zxp: Crystal structure of Peptidyl- tRNA Hydrolase from Vibrio cholerae
Classification: HYDROLASE
Source organism: Vibrio cholerae O1 biovar El Tor str. N16961
Experimental method: X-RAY DIFFRACTION
Resolution: 1.63 Å
Deposited: 2015-05-20
Authors: Shahid, S., Pal, R.K., Kabra, A., Yadav, R., Kumar, A., Arora, A.
PDB entry 4zxq: P22 Tail Needle Gp26 1-140 crystallized at pH 3.9
Classification: VIRAL PROTEIN
Source organism: Enterobacteria phage P22
Experimental method: X-RAY DIFFRACTION
Resolution: 2.75 Å
Deposited: 2015-05-20
Authors: Sankhala, R.S., Cingolani, G.
PDB entry 4zxr: Structure of Thaumatin wrapped in graphene within vacuum
Classification: PLANT PROTEIN
Source organism: Thaumatococcus daniellii
Experimental method: X-RAY DIFFRACTION
Resolution: 1.92 Å
Deposited: 2015-05-20
Authors: Aller, P., Warren, A.J., Trincao, J., Evans, G.
PDB entry 4zxs: HSV-1 nuclear egress complex
Classification: VIRAL PROTEIN
Source organism: Human herpesvirus 1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.772 Å
Deposited: 2015-05-20
Authors: Bigalke, J.M., Heldwein, E.E.
PDB entry 4zxt: Complex of ERK2 with catechol
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2015-05-20
Authors: Kurinov, I., Malakhova, M.
PDB entry 4zxu: 2.85 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) H448F/P449M double mutant from Staphylococcus aureus in complex with NAD+ and BME-free Cys289
Classification: OXIDOREDUCTASE
Source organism: Staphylococcus aureus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.85 Å
Deposited: 2015-05-20
Authors: Halavaty, A.S., Minasov, G., Chen, C., Joo, J.C., Yakunin, A.F., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4zxv: Streptomyces peucetius nitrososynthase DnmZ in ligand-free state
Classification: OXIDOREDUCTASE
Source organism: Streptomyces peucetius
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2015-05-20
Authors: Sartor, L.M., Vey, J.L.
PDB entry 4zxw: Crystal structure of SgcC5 protein from Streptomyces globisporus (complex with (R)-(-)-1-(2-naphthyl)-1,2-ethanediol and sucrose)
Classification: LIGASE
Source organism: Streptomyces globisporus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.187 Å
Deposited: 2015-05-20
Authors: Michalska, K., Bigelow, L., Jedrzejczak, R., Babnigg, G., Lohman, J., Ma, M., Rudolf, J., Chang, C.-Y., Shen, B., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
PDB entry 4zxx: FACTOR VIIA IN COMPLEX WITH THE INHIBITOR N-{3-[(2R)-1-{(2R)-2-[(1-aminoisoquinolin-6-yl)amino]-2-phenylacetyl}pyrrolidin-2-yl]-4-(propan-2-ylsulfonyl)phenyl}acetamide
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-05-20
Authors: Wei, A.
PDB entry 4zxy: FACTOR VIIA IN COMPLEX WITH THE INHIBITOR (2R)-2-[(1-aminoisoquinolin-6-yl)amino]-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaene-3,12-dione
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.06 Å
Deposited: 2015-05-20
Authors: Wei, A.
PDB entry 4zxz: Crystal structure of a highly thermal stable but inactive levoglucosan kinase.
Classification: DE NOVO PROTEIN
Source organism: Lipomyces starkeyi
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2015-05-20
Authors: Bacik, J.P., Klesmith, J.R., Whitehead, T.A.
PDB entry 4zy0: X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10q
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Plasmodium falciparum FcB1/Columbia
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2015-05-21
Authors: Drinkwater, N., McGowan, S.
PDB entry 4zy1: X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10r
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Plasmodium falciparum FcB1/Columbia
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2015-05-21
Authors: Drinkwater, N., McGowan, S.
PDB entry 4zy2: X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10o
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Plasmodium falciparum FcB1/Columbia
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2015-05-21
Authors: Drinkwater, N., McGowan, S.
PDB entry 4zy3: Crystal Structure of Keap1 in Complex with a small chemical compound, K67
Classification: TRANSCRIPTION
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2015-05-21
Authors: Fukutomi, T., Iso, T., Suzuki, T., Takagi, K., Mizushima, T., Komatsu, M., Yamamoto, M.
PDB entry 4zy4: Crystal structure of P21 activated kinase 1 in complex with an inhibitor compound 4
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-05-21
Authors: Rouge, R., Wang, W.
PDB entry 4zy5: Crystal Structure of p21-activated kinase 1 in complex with an inhibitor compound 17
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2015-05-21
Authors: Rouge, L., Wang, W.
PDB entry 4zy6: Crystal structure of P21-activated kinase 1 in complex with an inhibitor compound 29
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2015-05-21
Authors: Rouge, L., Wang, W.
PDB entry 4zy7: Crystal structure of a Mycobacterial protein
Classification: UNKNOWN FUNCTION
Source organism: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2015-05-21
Authors: Shahine, A., Rossjohn, J., Beddoe, T.
PDB entry 4zy8: K. lactis Lst4 longin domain
Classification: TRANSPORT PROTEIN
Source organism: Kluyveromyces lactis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.14 Å
Deposited: 2015-05-21
Authors: Pacitto, A., Ascher, D.B., Blundell, T.L.
PDB entry 4zy9: X-ray crystal structure of selenomethionine-labelled V110M mutant of chitosan-binding module 1 derived from chitosanase/glucanase from Paenibacillus sp. IK-5
Classification: HYDROLASE
Source organism: Paenibacillus fukuinensis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.2 Å
Deposited: 2015-05-21
Authors: Shinya, S., Oi, H., Kitaoku, Y., Ohnuma, T., Numata, T., Fukamizo, T.
PDB entry 4zya: The N-terminal extension domain of human asparaginyl-tRNA synthetase
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2015-05-21
Authors: Park, J.S., Park, M.C., Goughnour, P., Kim, H.S., Kim, S.J., Kim, H.J., Kim, S.H., Han, B.W.
PDB entry 4zyb: High resolution structure of M23 peptidase LytM with substrate analogue
Classification: HYDROLASE
Source organism: Staphylococcus aureus subsp. aureus NCTC 8325
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2015-05-21
Authors: Grabowska, M., Jagielska, E., Czapinska, H., Bochtler, M., Sabala, I.
PDB entry 4zyc: Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53-MDM2 interaction with a distinct binding mode: Hdm2 (MDM2) complexed with cpd5
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2015-05-21
Authors: Kallen, J.
PDB entry 4zyd: Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase in complex with modified DNA
Classification: TRANSFERASE
Source organism: Sulfolobus solfataricus; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.682 Å
Deposited: 2015-05-21
Authors: Miggiano, R., Rossi, F., Rizzi, M.
PDB entry 4zye: Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase
Classification: TRANSFERASE
Source organism: Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2015-05-21
Authors: Miggiano, R., Rossi, F., Rizzi, M.
PDB entry 4zyf: Discovery of NVP-CGM097 - a highly potent and selective MDM2 inhibitor undergoing phase 1 clinical trials in p53wt tumors: Hdm2 (MDM2) complexed with NVP-CGM097
Classification: CELL CYCLE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2015-05-21
Authors: Kallen, J.
PDB entry 4zyg: Crystal structure of methylated Sulfolobus solfataricus O6-methylguanine methyltransferase
Classification: TRANSFERASE
Source organism: Sulfolobus solfataricus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2015-05-21
Authors: Miggiano, R., Rossi, F., Rizzi, M.
PDB entry 4zyh: Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase C119L variant
Classification: TRANSFERASE
Source organism: Sulfolobus solfataricus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2015-05-21
Authors: Miggiano, R., Rossi, F., Rizzi, M.