LiteFold/PDB huggingface dataset:
PDB entry 4x56: Structure of the class D Beta-Lactamase OXA-160 V130D in Acyl-Enzyme Complex with Ceftazidime
Classification: HYDROLASE
Source organism: Acinetobacter baumannii
Experimental method: X-RAY DIFFRACTION
Resolution: 2.28 Å
Deposited: 2014-12-04
Authors: Clasman, J.R., June, C.M., Powers, R.A., Leonard, D.A.
PDB entry 4x57: Structure of an Arabidopsis E2 / Membrane-anchored Ubiquitin-fold Protein Complex
Classification: ligase/protein binding
Source organism: Arabidopsis thaliana
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2014-12-04
Authors: Korolev, S., Koroleva, O., Lu, X., Downes, B.
PDB entry 4x58: Anthranilate phosphoribosyl transferase variant N138A from Mycobacterium tuberculosis in complex with PRPP and Mg
Classification: TRANSFERASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2014-12-04
Authors: Cookson, T.V.M., Evans, G.L., Parker, E.J., Lott, J.S.
PDB entry 4x59: Anthranilate phosphoribosyltransferase variant P180A from Mycobacterium tuberculosis in complex with PRPP and Mg
Classification: TRANSFERASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2014-12-04
Authors: Cookson, T.V.M., Evans, G.L., Parker, E.J., Lott, J.S.
PDB entry 4x5a: Anthranilate phosphoribosyltransferase variant R193A from Mycobacterium tuberculosis remains ligand-free when co-crystallised with PRPP and Mg
Classification: TRANSFERASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.93 Å
Deposited: 2014-12-05
Authors: Cookson, T.V.M., Parker, E.J., Lott, J.S.
PDB entry 4x5b: Anthranilate phosphoribosyltransferase variant R193L from Mycobacterium tuberculosis in complex with PRPP and Mg
Classification: TRANSFERASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.47 Å
Deposited: 2014-12-05
Authors: Cookson, T.V.M., Parker, E.J., Lott, J.S.
PDB entry 4x5c: Anthranilate phosphoribosyltransferase variant R193L from Mycobacterium tuberculosis with pyrophosphate/PRPP and Mg2+ bound
Classification: TRANSFERASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.33 Å
Deposited: 2014-12-05
Authors: Cookson, T.V.M., Parker, E.J., Lott, J.S.
PDB entry 4x5d: Anthranilate phosphoribosyltransferase variant R193A from Mycobacterium tuberculosis with anthranilate bound
Classification: TRANSFERASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2014-12-05
Authors: Cookson, T.V.M., Parker, E.J., Lott, J.S.
PDB entry 4x5e: Anthranilate phosphoribosyltransferase variant R194A from Mycobacterium tuberculosis with pyrophosphate, Mg2+ and anthranilate bound
Classification: TRANSFERASE
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.77 Å
Deposited: 2014-12-05
Authors: Cookson, T.V.M., Evans, G.L., Parker, E.J., Lott, J.S.
PDB entry 4x5f: ecDHFR complexed with folate and NADP+ at 0.1 MPa
Classification: OXIDOREDUCTASE
Source organism: Escherichia coli K12
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2014-12-05
Authors: Yamada, H., Watanabe, N., Nagae, T.
PDB entry 4x5g: ecDHFR complexed with folate and NADP+ at 270 MPa
Classification: OXIDOREDUCTASE
Source organism: Escherichia coli K12
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2014-12-05
Authors: Yamada, H., Watanabe, N., Nagae, T.
PDB entry 4x5h: ecDHFR complexed with folate and NADP+ at 500 MPa
Classification: OXIDOREDUCTASE
Source organism: Escherichia coli  K12
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2014-12-05
Authors: Yamada, H., Watanabe, N., Nagae, T.
PDB entry 4x5i: ecDHFR complexed with folate and NADP+ at 660 MPa
Classification: OXIDOREDUCTASE
Source organism: Escherichia coli K12
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2014-12-05
Authors: Yamada, H., Watanabe, N., Nagae, T.
PDB entry 4x5j: ecDHFR complexed with folate and NADP+ at 750 MPa
Classification: OXIDOREDUCTASE
Source organism: Escherichia coli K12
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2014-12-05
Authors: Yamada, H., Watanabe, N., Nagae, T.
PDB entry 4x5k: Human NAA50 complex with coenzyme A and an acetylated peptide
Classification: Transferase/Peptide
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.494 Å
Deposited: 2014-12-05
Authors: Reddi, R., Addlagatta, A.
PDB entry 4x5l: Crystal structure of Dscam1 Ig7 domain, isoform 9
Classification: CELL ADHESION
Source organism: Drosophila melanogaster
Experimental method: X-RAY DIFFRACTION
Resolution: 2.374 Å
Deposited: 2014-12-05
Authors: Chen, Q., Yu, Y., Li, S.A., Cheng, L.
PDB entry 4x5m: Crystal structure of SemiSWEET in the inward-open conformation
Classification: TRANSPORT PROTEIN
Source organism: Escherichia coli UMEA 3162-1
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2014-12-05
Authors: Lee, Y., Nishizawa, T., Yamashita, K., Ishitani, R., Nureki, O.
PDB entry 4x5n: Crystal structure of SemiSWEET in the inward-open and outward-open conformations
Classification: TRANSPORT PROTEIN
Source organism: Escherichia coli UMEA 3162-1
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2014-12-05
Authors: Lee, Y., Nishizawa, T., Yamashita, K., Ishitani, R., Nureki, O.
PDB entry 4x5o: Human histidine tRNA synthetase
Classification: LIGASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2014-12-05
Authors: Kim, Y.K., Jeon, Y.H.
PDB entry 4x5p: Crystal structure of FimH in complex with a benzoyl-amidophenyl alpha-D-mannopyranoside
Classification: SUGAR BINDING PROTEIN
Source organism: Escherichia coli K-12
Experimental method: X-RAY DIFFRACTION
Resolution: 0.997 Å
Deposited: 2014-12-05
Authors: Preston, R.C., Jakob, R.P., Fiege, B., Zihlmann, P., Rabbani, S., Schwardt, O., Jiang, X., Ernst, B., Maier, T.
PDB entry 4x5q: Crystal structure of FimH in complex with 5-nitro-indolinylphenyl alpha-D-mannopyranoside
Classification: SUGAR BINDING PROTEIN
Source organism: Escherichia coli K-12
Experimental method: X-RAY DIFFRACTION
Resolution: 1.12 Å
Deposited: 2014-12-05
Authors: Preston, R.C., Jakob, R.P., Fiege, B., Zihlmann, P., Rabbani, S., Schwardt, O., Jiang, X., Ernst, B., Maier, T.
PDB entry 4x5r: Crystal structure of FimH in complex with a squaryl-phenyl alpha-D-mannopyranoside derivative
Classification: SUGAR BINDING PROTEIN
Source organism: Escherichia coli K-12
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2014-12-05
Authors: Preston, R.C., Jakob, R.P., Fiege, B., Zihlmann, P., Rabbani, S., Schwardt, O., Jiang, X., Ernst, B., Maier, T.
PDB entry 4x5s: The crystal structure of an alpha carbonic anhydrase from the extremophilic bacterium Sulfurihydrogenibium azorense.
Classification: LYASE
Source organism: Sulfurihydrogenibium azorense
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2014-12-05
Authors: De Simone, G., Alterio, V., Di Fiore, A.
PDB entry 4x5t: alpha 1 glycine receptor transmembrane structure fused to the extracellular domain of GLIC
Classification: SIGNALING PROTEIN
Source organism: Gloeobacter violaceus; Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.5 Å
Deposited: 2014-12-05
Authors: Sauguet, L., Corringer, P.J., Huon, C., Delarue, M.
PDB entry 4x5u: X-ray crystal structure of CagL at pH 4.2
Classification: CELL ADHESION
Source organism: Helicobacter pylori
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2014-12-05
Authors: Sundberg, E.J., Bonsor, D.A., Diederichs, K.
PDB entry 4x5v: Crystal structure of the post-catalytic nick complex of DNA polymerase lambda with a templating A and incorporated 8-oxo-dGMP
Classification: TRANSFERASE/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2014-12-05
Authors: Burak, M.J., Guja, K.E., Garcia-Diaz, M.
PDB entry 4x5w: HLA-DR1 with CLIP102-120(M107W)
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.34 Å
Deposited: 2014-12-06
Authors: Guenther, S., Freund, C.
PDB entry 4x5x: HLA-DR1 mutant bN82A with covalently linked CLIP106-120(M107W)
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.199 Å
Deposited: 2014-12-06
Authors: Guenther, S., Freund, C.
PDB entry 4x5y: Menin in complex with MI-503
Classification: protein binding/inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.59 Å
Deposited: 2014-12-06
Authors: Pollock, J., Borkin, D., Cierpicki, T., Grembecka, J.
PDB entry 4x5z: menin in complex with MI-136
Classification: protein binding/inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.86 Å
Deposited: 2014-12-06
Authors: Pollock, J., Borkin, D., Cierpicki, T., Grembecka, J.
PDB entry 4x60: Crystal structure of PRMT5:MEP50 with EPZ015666 and sinefungin
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2014-12-06
Authors: Boriack-Sjodin, P.A.
PDB entry 4x61: Crystal structure of PRMT5:MEP50 with EPZ015666 and SAM
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.85 Å
Deposited: 2014-12-06
Authors: Boriack-Sjodin, P.A.
PDB entry 4x62: Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
Classification: Ribosome/antibiotic
Source organism: Thermus thermophilus; Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579); Thermus thermophilus HB8
Experimental method: X-RAY DIFFRACTION
Resolution: 3.4492 Å
Deposited: 2014-12-06
Authors: Demirci, H., Chen, J., Choi, J., Soltis, M., Puglisi, J.D.
PDB entry 4x63: Crystal structure of PRMT5:MEP50 with EPZ015666 and SAH
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.05 Å
Deposited: 2014-12-06
Authors: Boriack-Sjodin, P.A.
PDB entry 4x64: Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
Classification: Ribosome/antibiotic
Source organism: Thermus thermophilus; Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579); Thermus thermophilus HB8
Experimental method: X-RAY DIFFRACTION
Resolution: 3.35 Å
Deposited: 2014-12-06
Authors: Demirci, H., Chen, J., Choi, J., Soltis, M., Puglisi, J.D.
PDB entry 4x65: Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
Classification: Ribosome/antibiotic
Source organism: Thermus thermophilus; Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579); Thermus thermophilus HB8
Experimental method: X-RAY DIFFRACTION
Resolution: 3.345 Å
Deposited: 2014-12-06
Authors: Demirci, H., Chen, J., Choi, J., Soltis, M., Puglisi, J.D.
PDB entry 4x66: Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
Classification: Ribosome/antibiotic
Source organism: Thermus thermophilus; Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579); Thermus thermophilus HB8
Experimental method: X-RAY DIFFRACTION
Resolution: 3.446 Å
Deposited: 2014-12-06
Authors: Demirci, H., Chen, J., Choi, J., Soltis, M., Puglisi, J.D.
PDB entry 4x67: Crystal structure of elongating yeast RNA polymerase II stalled at oxidative Cyclopurine DNA lesions.
Classification: TRANSCRIPTION/DNA
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 4.1 Å
Deposited: 2014-12-07
Authors: Wang, L., Chong, J., Wang, D.
PDB entry 4x68: Crystal Structure of OP0595 complexed with AmpC
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Pseudomonas aeruginosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.68 Å
Deposited: 2014-12-07
Authors: Yamada, M., Watanabe, T.
PDB entry 4x69: Crystal structure of OP0595 complexed with CTX-M-44
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 1.42 Å
Deposited: 2014-12-07
Authors: Yamada, M., Watanabe, T.
PDB entry 4x6a: Crystal structure of yeast RNA polymerase II encountering oxidative Cyclopurine DNA lesions
Classification: TRANSCRIPTION/DNA
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 3.96 Å
Deposited: 2014-12-07
Authors: Wang, L., Chong, J., Wang, D.
PDB entry 4x6b: BK6 TCR apo structure
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2014-12-07
Authors: Birkinshaw, R.W., Rossjohn, J.
PDB entry 4x6c: CD1a ternary complex with lysophosphatidylcholine and BK6 TCR
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.8 Å
Deposited: 2014-12-08
Authors: Birkinshaw, R.W., Rossjohn, J.
PDB entry 4x6d: CD1a ternary complex with endogenous lipids and BK6 TCR
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.98 Å
Deposited: 2014-12-08
Authors: Birkinshaw, R.W., Rossjohn, J.
PDB entry 4x6e: CD1a binary complex with lysophosphatidylcholine
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2014-12-08
Authors: Birkinshaw, R.W., Rossjohn, J.
PDB entry 4x6f: CD1a binary complex with sphingomyelin
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.91 Å
Deposited: 2014-12-08
Authors: Birkinshaw, R.W., Rossjohn, J.
PDB entry 4x6g: Full-length OxyR C199D from pseudomonas aeruginosa
Classification: DNA BINDING PROTEIN
Source organism: Pseudomonas aeruginosa PAO1
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2014-12-08
Authors: Jo, I., Ha, N.C.
PDB entry 4x6h: Development of N-(Functionalized benzoyl)-homocycloleucyl-glycinonitriles as Potent Cathepsin K Inhibitors.
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1 Å
Deposited: 2014-12-08
Authors: Borisek, J., Mohar, B., Vizovisek, M., Sosnowski, P., Turk, D., Turk, B., Novic, M.
PDB entry 4x6i: Development of N-(Functionalized benzoyl)-homocycloleucyl-glycinonitriles as Potent Cathepsin K Inhibitors.
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.87 Å
Deposited: 2014-12-08
Authors: Borisek, J., Mohar, B., Vizovisek, M., Sosnowski, P., Turk, D., Turk, B., Novic, M.
PDB entry 4x6j: Development of N-(Functionalized benzoyl)-homocycloleucyl-glycinonitriles as Potent Cathepsin K Inhibitors.
Classification: HYDROLASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.59 Å
Deposited: 2014-12-08
Authors: Borisek, J., Mohar, B., Vizovisek, M., Sosnowski, P., Turk, D., Turk, B., Novic, M.
PDB entry 4x6k: Crystal structure of the intramolecular trans-sialidase from Ruminococcus gnavus in complex with Siastatin B
Classification: HYDROLASE
Source organism: Ruminococcus gnavus CC55_001C
Experimental method: X-RAY DIFFRACTION
Resolution: 1.94 Å
Deposited: 2014-12-08
Authors: Owen, C.D., Tailford, L.E., Taylor, G.L., Juge, N.
PDB entry 4x6l: Crystal structure of S. aureus TarM in complex with UDP
Classification: TRANSFERASE
Source organism: Staphylococcus aureus subsp. aureus 21178
Experimental method: X-RAY DIFFRACTION
Resolution: 3.19 Å
Deposited: 2014-12-08
Authors: Worrall, L.J., Sobhanifar, S., Gruninger, R.J., Strynadka, N.C.
PDB entry 4x6m: FACTOR XIA IN COMPLEX WITH THE INHIBITOR 1-{(1S)-1-[4-(3-amino-1H-indazol-6-yl)-5-chloro-1H-imidazol-2-yl]-2-phenylethyl}-3-[2-(aminomethyl)-5-chlorobenzyl]urea
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2014-12-08
Authors: Wei, A.
PDB entry 4x6n: FACTOR XIA IN COMPLEX WITH THE INHIBITOR 1-{(1S)-1-[4-(3-amino-1H-indazol-6-yl)-5-chloro-1H-imidazol-2-yl]-2-phenylethyl}-3-[5-chloro-2-(1H-tetrazol-1-yl)benzyl]urea
Classification: hydrolase/hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2014-12-08
Authors: Wei, A.
PDB entry 4x6o: FACTOR XIA IN COMPLEX WITH THE INHIBITOR methyl (4-{4-chloro-2-[(1S)-1-({3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]propanoyl}amino)-2-phenylethyl]-1H-imidazol-5-yl}phenyl)carbamate
Classification: hydrolase/hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2014-12-08
Authors: Wei, A.
PDB entry 4x6p: FACTOR XIA (PICHIA PASTORIS; C500S [C122S]) IN COMPLEX WITH THE INHIBITOR (2E)-N-{(1S)-1-[4-(3-amino-1H-indazol-6-yl)-1H-imidazol-2-yl]-2-phenylethyl}-3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]prop-2-enamide
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.93 Å
Deposited: 2014-12-08
Authors: Sheriff, S.
PDB entry 4x6q: An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes
Classification: TRANSFERASE
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.52 Å
Deposited: 2014-12-08
Authors: Zhang, P., Ye, F., Bastidas, A.C., Kornev, A.P., Ginsberg, M.H., Taylor, S.S.
PDB entry 4x6r: An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes
Classification: TRANSFERASE
Source organism: Bos taurus; Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2014-12-09
Authors: Zhang, P., Ye, F., Bastidas, A.C., Kornev, A.P., Ginsberg, M.H., Wu, J., Taylor, S.S.
PDB entry 4x6s: Grb7 SH2 domain with phosphotyrosine mimetic inhibitor peptide
Classification: Signaling Protein/Inhibitor
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.55 Å
Deposited: 2014-12-09
Authors: Watson, G.M., Panjikar, S., Wilce, M.C., Wilce, J.A.
PDB entry 4x6t: M.tuberculosis betalactamase complexed with inhibitor EC19
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2014-12-09
Authors: Hazra, S.
PDB entry 4x6u: Crystal Structure of lipase from Geobacillus stearothermophilus T6
Classification: HYDROLASE
Source organism: Geobacillus stearothermophilus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.201 Å
Deposited: 2014-12-09
Authors: Kanteev, M., Dror, A., Gihaz, S., Fishman, A.
PDB entry 4x6x: Human soluble epoxide hydrolase in complex with a three substituted cyclopropane derivative
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2014-12-09
Authors: Chiyo, N., Takai, K., Ishii, T.
PDB entry 4x6y: Human soluble epoxide hydrolase in complex with a cyclopropyl urea derivative
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2014-12-09
Authors: Chiyo, N., Takai, K., Ishii, T.
PDB entry 4x6z: Yeast 20S proteasome in complex with PR-VI modulator
Classification: HYDROLASE
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2014-12-09
Authors: Rostankowski, R., Witkowska, J., Borek, D., Otwinowski, Z., Jankowska, E.
PDB entry 4x71: Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant A269T
Classification: HYDROLASE
Source organism: Geobacillus stearothermophilus T6
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2014-12-09
Authors: Kanteev, M., Dror, A., Gihaz, S., Shahar, A., Fishman, A.
PDB entry 4x7b: Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant H86Y/A269T
Classification: HYDROLASE
Source organism: Geobacillus stearothermophilus T6
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2014-12-09
Authors: Kanteev, M., Dror, A., Gihaz, S., Fishman, A.
PDB entry 4x7c: Crystal structure of Saga-2006 GII.4 P domain in complex with Nano-85
Classification: VIRAL PROTEIN
Source organism: Norovirus Hu/GII-4/Saga1/2006/JP; Vicugna pacos
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2014-12-09
Authors: Koromyslova, A.D., Hansman, G.S.
PDB entry 4x7d: Crystal structure of 2012 NSW GII.4 P domain in complex with Nano-85
Classification: VIRAL PROTEIN
Source organism: Lama glama; Norovirus Hu/GII.4/Sydney/NSW0514/2012/AU
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2014-12-09
Authors: Koromyslova, A.D., Hansman, G.S.
PDB entry 4x7e: Crystal structure of norovirus GII.10 P domain in complex with Nano-85
Classification: VIRAL PROTEIN
Source organism: Norovirus; Vicugna pacos
Experimental method: X-RAY DIFFRACTION
Resolution: 2.11 Å
Deposited: 2014-12-09
Authors: Hansman, G.H., Koromyslova, A.D.
PDB entry 4x7f: Crystal structure of norovirus GII.10 P domain in complex with Nano-25
Classification: VIRAL PROTEIN
Source organism: Norwalk virus; Vicugna pacos
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2014-12-09
Authors: Koromyslova, A.D., Hansman, G.S.
PDB entry 4x7g: CobK precorrin-6A reductase
Classification: OXIDOREDUCTASE
Source organism: Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.22 Å
Deposited: 2014-12-09
Authors: Gu, S., Deery, E., Warren, M.J., Pickersgill, R.W.
PDB entry 4x7h: Co-crystal Structure of PERK bound to N-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}-1-methyl-3-oxo-2-phenyl-5-(pyridin-4-yl)-2,3-dihydro-1H-pyrazole-4-carboxamide inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2 Å
Deposited: 2014-12-09
Authors: Shaffer, P.L., Bellon, S.F., Long, A.M., Chen, H.
PDB entry 4x7i: Crystal Structure of BACE with amino thiazine inhibitor LY2886721
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.77 Å
Deposited: 2014-12-09
Authors: Timm, D.E.
PDB entry 4x7j: Co-crystal Structure of PERK with 2-amino-N-[4-methoxy-3-(trifluoromethyl)phenyl]-4-methyl-3-[2-(methylamino)quinazolin-6-yl]benzamide inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2014-12-09
Authors: Shaffer, P.L., Long, A.M., Chen, H.
PDB entry 4x7k: Co-crystal Structure of PERK bound to 4-{2-amino-3-[5-fluoro-2-(methylamino)quinazolin-6-yl]-4-methylbenzoyl}-1-methyl-2,5-diphenyl-1,2-dihydro-3H-pyrazol-3-one inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8 Å
Deposited: 2014-12-09
Authors: Shaffer, P.L., Long, A.M., Chen, H.
PDB entry 4x7l: Co-crystal Structure of PERK bound to 4-{2-amino-4-methyl-3-[2-(methylamino)-1,3-benzothiazol-6-yl]benzoyl}-1-methyl-2,5-diphenyl-1,2-dihydro-3H-pyrazol-3-one inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2014-12-09
Authors: Shaffer, P.L., Long, A.M., Chen, H.
PDB entry 4x7m: Crystal structure of S. aureus TarM G117R mutant in complex with UDP and UDP-GlcNAc
Classification: TRANSFERASE
Source organism: Staphylococcus aureus subsp. aureus 21178
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2014-12-09
Authors: Worrall, L.J., Sobhanifar, S., Strynadka, N.C.
PDB entry 4x7n: Co-crystal Structure of PERK bound to 4-[2-amino-4-methyl-3-(2-methylquinolin-6-yl)benzoyl]-1-methyl-2,5-diphenyl-1,2-dihydro-3H-pyrazol-3-one inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2014-12-09
Authors: Shaffer, P.L., Long, A.M., Chen, H.
PDB entry 4x7o: Co-crystal Structure of PERK bound to 1-[5-(4-amino-2,7-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-[3-fluoro-5-(trifluoromethyl)phenyl]ethanone inhibitor
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.65 Å
Deposited: 2014-12-09
Authors: Shaffer, P.L., Long, A.M., Chen, H.
PDB entry 4x7p: Crystal structure of apo S. aureus TarM
Classification: TRANSFERASE
Source organism: Staphylococcus aureus subsp. aureus 21178
Experimental method: X-RAY DIFFRACTION
Resolution: 3.4 Å
Deposited: 2014-12-09
Authors: Worrall, L.J., Sobhanifar, S., Gruninger, R.J., Strynadka, N.C.
PDB entry 4x7q: PIM2 kinase in complex with Compound 1s
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.33 Å
Deposited: 2014-12-09
Authors: Marcotte, D.J., Silvian, L.F.
PDB entry 4x7r: Crystal structure of S. aureus TarM G117R mutant in complex with Fondaparinux, alpha-GlcNAc-glycerol and UDP
Classification: TRANSFERASE
Source organism: Staphylococcus aureus subsp. aureus 21178
Experimental method: X-RAY DIFFRACTION
Resolution: 2.15 Å
Deposited: 2014-12-09
Authors: Worrall, L.J., Sobhanifar, S., Strynadka, N.C.
PDB entry 4x7s: Structure of omalizumab Fab fragment crystal form 1
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2014-12-09
Authors: Jensen, R.K., Andersen, G.R.
PDB entry 4x7t: Structure of Omalizumab Fab fragment, crystal form 2
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2014-12-09
Authors: Jensen, R.K., Andersen, G.R.
PDB entry 4x7u: MycF mycinamicin III 3'-O-methyltransferase in complex with Mg, SAH and mycinamicin III (substrate)
Classification: Transferase/Antibiotic
Source organism: Micromonospora griseorubida
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65 Å
Deposited: 2014-12-09
Authors: Bernard, S.M., Smith, J.L.
PDB entry 4x7v: MycF mycinamicin III 3'-O-methyltransferase (E35Q, E139A variant) in complex with Mg, SAH and mycinamicin IV (product)
Classification: Transferase/Antibiotic
Source organism: Micromonospora griseorubida
Experimental method: X-RAY DIFFRACTION
Resolution: 1.45 Å
Deposited: 2014-12-09
Authors: Bernard, S.M., Smith, J.L.
PDB entry 4x7w: MycF mycinamicin III 3'-O-methyltransferase (E35Q, E139A variant) in complex with Mg, SAH and mycinamicin VI (MycE substrate)
Classification: Transferase/Antiobiotic
Source organism: Micromonospora griseorubida
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2014-12-09
Authors: Bernard, S.M., Smith, J.L.
PDB entry 4x7x: MycF mycinamicin III 3'-O-methyltransferase (E35Q, E139A variant) in complex with Mg, SAH and macrocin
Classification: Transferase/Antibiotic
Source organism: Micromonospora griseorubida
Experimental method: X-RAY DIFFRACTION
Resolution: 1.75 Å
Deposited: 2014-12-09
Authors: Bernard, S.M., Smith, J.L.
PDB entry 4x7y: MycF mycinamicin III 3'-O-methyltransferase (E35Q, M56A, E139A variant) in complex with Mg and SAH
Classification: Transferase/Antibiotic
Source organism: Micromonospora griseorubida
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2014-12-09
Authors: Bernard, S.M., Smith, J.L.
PDB entry 4x7z: MycF mycinamicin III 3'-O-methyltransferase (E35Q, M56A, E139A variant) in complex with Mg, SAH and mycinamicin III (substrate)
Classification: Transferase/Antibiotic
Source organism: Micromonospora griseorubida
Experimental method: X-RAY DIFFRACTION
Resolution: 1.44 Å
Deposited: 2014-12-09
Authors: Bernard, S.M., Smith, J.L.
PDB entry 4x80: Crystal Structure of murine 7B4 Fab monoclonal antibody against ADAMTS5
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2014-12-09
Authors: Larkin, J., Lohr, T.A., Elefante, L., Shearin, J., Matico, R., Su, J.-L., Xue, Y., Liu, F., Genell, C., Miller, R.E., Tran, P.B., Malfait, A.-M., Maier, C.C., Matheny, C.J.
PDB entry 4x81: MycF mycinamicin III 3'-O-methyltransferase (E35Q, M56A, E139A variant) in complex with Mg, SAH and mycinamicin VI (MycE substrate)
Classification: Transferase/Antibiotic
Source organism: Micromonospora griseorubida
Experimental method: X-RAY DIFFRACTION
Resolution: 1.59 Å
Deposited: 2014-12-09
Authors: Bernard, S.M., Smith, J.L.
PDB entry 4x82: Crystal Structure of the Extracellular Domain of ZIP4
Classification: TRANSPORT PROTEIN
Source organism: Pteropus alecto
Experimental method: X-RAY DIFFRACTION
Resolution: 2.76 Å
Deposited: 2014-12-09
Authors: Zhang, T., Sui, D.X., Hu, J.
PDB entry 4x83: Crystal structure of Dscam1 isoform 7.44, N-terminal four Ig domains
Classification: CELL ADHESION
Source organism: Drosophila melanogaster
Experimental method: X-RAY DIFFRACTION
Resolution: 1.902 Å
Deposited: 2014-12-10
Authors: Chen, Q., Yu, Y., Li, S.A., Cheng, L.
PDB entry 4x84: Crystal structure of Ribose-5-phosphate isomerase A from Pseudomonas aeruginosa
Classification: ISOMERASE
Source organism: Pseudomonas aeruginosa
Experimental method: X-RAY DIFFRACTION
Resolution: 1.25 Å
Deposited: 2014-12-10
Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
PDB entry 4x85: Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant H86Y/A269T/R374W
Classification: HYDROLASE
Source organism: Geobacillus stearothermophilus T6
Experimental method: X-RAY DIFFRACTION
Resolution: 2.192 Å
Deposited: 2014-12-10
Authors: Kanteev, M., Dror, A., Gihaz, S., Fishman, A.
PDB entry 4x86: Crystal structure of BAG6-Ubl4a complex
Classification: PROTEIN BINDING
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85 Å
Deposited: 2014-12-10
Authors: Kuwabara, N., Kato, R.
PDB entry 4x88: E178D Selectivity filter mutant of NavMS voltage-gated pore
Classification: TRANSPORT PROTEIN
Source organism: Magnetococcus marinus MC-1
Experimental method: X-RAY DIFFRACTION
Resolution: 3.5 Å
Deposited: 2014-12-10
Authors: Naylor, C.E., Bagneris, C., Wallace, B.A.
PDB entry 4x89: NavMs voltage-gated sodium channal pore and C-terminal domain soaked with Silver nitrate
Classification: TRANSPORT PROTEIN
Source organism: Magnetococcus marinus MC-1
Experimental method: X-RAY DIFFRACTION
Resolution: 2.62 Å
Deposited: 2014-12-10
Authors: Naylor, C.E., Bagneris, C., Wallace, B.A.
PDB entry 4x8a: NavMS pore and C-terminal domain grown from protein purified in LiCl
Classification: TRANSPORT PROTEIN
Source organism: Magnetococcus sp. (strain MC-1)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.02 Å
Deposited: 2014-12-10
Authors: Naylor, C.E., Bagneris, C., Wallace, B.A.
PDB entry 4x8b: Ergothioneine-biosynthetic sulfoxide synthase EgtB, apo form
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium thermoresistibile ATCC 19527
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2014-12-10
Authors: Vit, A., Goncharenko, K.V., Blankenfeldt, W., Seebeck, F.P.
PDB entry 4x8c: Crystal structure of human peptidylarginine deiminase type4 (PAD4) in complex with GSK147
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1 Å
Deposited: 2014-12-10
Authors: Lewis, H.D., Bax, B.D., Chung, C.-W., Polyakova, O., Thorpe, J.
PDB entry 4x8d: Ergothioneine-biosynthetic sulfoxide synthase EgtB in complex with N,N-dimethyl-histidine and gamma-glutamyl-cysteine
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium thermoresistibile ATCC 19527
Experimental method: X-RAY DIFFRACTION
Resolution: 1.98 Å
Deposited: 2014-12-10
Authors: Vit, A., Goncharenko, K.V., Blankenfeldt, W., Seebeck, F.P.
PDB entry 4x8e: Ergothioneine-biosynthetic sulfoxide synthase EgtB in complex with N,N,N-trimethyl-histidine
Classification: OXIDOREDUCTASE
Source organism: Mycobacterium thermoresistibile ATCC 19527
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2014-12-10
Authors: Vit, A., Goncharenko, K.V., Blankenfeldt, W., Seebeck, F.P.
PDB entry 4x8f: Vibrio cholerae O395 Ribokinase in apo form
Classification: TRANSFERASE
Source organism: Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Experimental method: X-RAY DIFFRACTION
Resolution: 3.4 Å
Deposited: 2014-12-10
Authors: Paul, R., Patra, M.D., Sen, U.
PDB entry 4x8g: Crystal structure of human peptidylarginine deiminase type4 (PAD4) in complex with GSK199
Classification: Hydrolase/Hydrolase Inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.29 Å
Deposited: 2014-12-10
Authors: Lewis, H.D., Bax, B.D., Chung, C.-W., Polyakova, O., Thorpe, J.
PDB entry 4x8h: Crystal structure of E. coli Adenylate kinase P177A mutant
Classification: TRANSFERASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2014-12-10
Authors: Sauer-Eriksson, A.E., Kovermann, M., Aden, J., Grundstrom, C., Wolf-Watz, M., Sauer, U.H.
PDB entry 4x8i: de novo crystal structure of the Pyrococcus Furiosus TET3 aminopeptidase
Classification: HYDROLASE
Source organism: Pyrococcus furiosus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2014-12-10
Authors: Colombo, M.
PDB entry 4x8j: Crystal Structure of murine 12F4 Fab monoclonal antibody against ADAMTS5
Classification: IMMUNE SYSTEM
Source organism: Mus musculus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2014-12-10
Authors: Larkin, J., Lohr, T.A., Elefante, L., Shearin, J., Matico, R., Su, J.-L., Xue, Y., Liu, F., Genell, C., Miller, R.E., Tran, P.B., Malfait, A.-M., Maier, C.C., Matheny, C.J.
PDB entry 4x8k: Mycobacterium tuberculosis RbpA-SID in complex with SigmaA domain 2
Classification: TRANSCRIPTION ACTIVATOR
Source organism: Mycobacterium tuberculosis
Experimental method: X-RAY DIFFRACTION
Resolution: 2.202 Å
Deposited: 2014-12-10
Authors: Hubin, E.A., Flack, J.E., Tabib-Salazar, A., Paget, M.S., Darst, S.A., Campbell, E.A.
PDB entry 4x8l: Crystal structure of E. coli Adenylate kinase P177A mutant in complex with inhibitor Ap5a
Classification: TRANSFERASE
Source organism: Escherichia coli K-12
Experimental method: X-RAY DIFFRACTION
Resolution: 1.7 Å
Deposited: 2014-12-10
Authors: Sauer-Eriksson, A.E., Kovermann, M., Aden, J., Grundstrom, C., Wolf-Watz, M., Sauer, U.H.
PDB entry 4x8m: Crystal structure of E. coli Adenylate kinase Y171W mutant
Classification: TRANSFERASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2014-12-10
Authors: Sauer-Eriksson, A.E., Kovermann, M., Aden, J., Grundstrom, C., Wolf-Watz, M., Sauer, U.H.
PDB entry 4x8n: Crystal structure of Ash2L SPRY domain in complex with phosphorylated RbBP5
Classification: PROTEIN BINDING
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2014-12-10
Authors: Zhang, P., Chaturvedi, C.P., Brunzelle, J.S., Skiniotis, G., Brand, M., Shilatifard, A., Couture, J.-F.
PDB entry 4x8o: Crystal structure of E. coli Adenylate kinase Y171W mutant in complex with inhibitor Ap5a
Classification: TRANSFERASE
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2014-12-10
Authors: Sauer-Eriksson, A.E., Kovermann, M., Aden, J., Grundstrom, C., Wolf-Watz, M., Sauer, U.H.
PDB entry 4x8p: Crystal structure of Ash2L SPRY domain in complex with RbBP5
Classification: PROTEIN BINDING
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2014-12-10
Authors: Zhang, P., Chaturvedi, C.P., Brunzelle, J.S., Skiniotis, G., Brand, M., Shilatifard, A., Couture, J.-F.
PDB entry 4x8q: X-ray crystal structure of AlkD2 from Streptococcus mutans
Classification: UNKNOWN FUNCTION
Source organism: Streptococcus mutans
Experimental method: X-RAY DIFFRACTION
Resolution: 1.729 Å
Deposited: 2014-12-10
Authors: Mullins, E.A., Shi, R., Eichman, B.F.
PDB entry 4x8r: CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM Rhodobacter sphaeroides (Rsph17029_2138, TARGET EFI-510205) WITH BOUND Glucuronate
Classification: SOLUTE-BINDING PROTEIN
Source organism: Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.9 Å
Deposited: 2014-12-10
Authors: Yadava, U., Vetting, M.W., Al Obaidi, N.F., Toro, R., Morisco, L.L., Benach, J., Wasserman, S.R., Attonito, J.D., Scott Glenn, A., Chamala, S., Chowdhury, S., Lafleur, J., Love, J., Seidel, R.D., Whalen, K.L., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4x8s: FACTOR VIIA IN COMPLEX WITH THE INHIBITOR 4-BROMO-2-METHOXYPHENOL
Classification: hydrolase/hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2014-12-10
Authors: Wei, A.
PDB entry 4x8t: FACTOR VIIA IN COMPLEX WITH THE INHIBITOR 7-chloro-3,4-dihydroisoquinolin-1(2H)-one
Classification: hydrolase/hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2014-12-10
Authors: Wei, A.
PDB entry 4x8u: FACTOR VIIA IN COMPLEX WITH THE INHIBITOR 5-CHLORO-1H-INDOLE-2-CARBOXYLIC ACID
Classification: hydrolase/hydrolase inhibitor
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2014-12-10
Authors: Wei, A.
PDB entry 4x8v: FACTOR VIIA IN COMPLEX WITH THE INHIBITOR (methyl {3-[(2R)-1-{(2R)-2-(3,4-dimethoxyphenyl)-2-[(1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]acetyl}pyrrolidin-2-yl]-4-(propan-2-ylsulfonyl)phenyl}carbamate)
Classification: HYDROLASE/HYDROLASE INHIBITOR
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2014-12-10
Authors: Wei, A.
PDB entry 4x8w: dsRBD3 of Loquacious
Classification: GENE REGULATION
Source organism: Drosophila melanogaster
Experimental method: X-RAY DIFFRACTION
Resolution: 2.647 Å
Deposited: 2014-12-10
Authors: Jakob, L., Treiber, N., Treiber, T., Stotz, M., Meister, G.
PDB entry 4x8x: Crystal structure of Dscam1 isoform 1.9, N-terminal four Ig domains
Classification: CELL ADHESION
Source organism: Drosophila melanogaster
Experimental method: X-RAY DIFFRACTION
Resolution: 2.5 Å
Deposited: 2014-12-11
Authors: Chen, Q.
PDB entry 4x8y: Crystal structure of human PGRMC1 cytochrome b5-like domain
Classification: MEMBRANE PROTEIN
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.95 Å
Deposited: 2014-12-11
Authors: Nakane, T., Yamamoto, T., Shimamura, T., Kobayashi, T., Kabe, Y., Suematsu, M.
PDB entry 4x90: Crystal structure of Lysosomal Phospholipase A2
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.84 Å
Deposited: 2014-12-11
Authors: Glukhova, A., Tesmer, J.J.G.
PDB entry 4x91: Crystal structure of Lysosomal Phospholipase A2 in complex with Isopropyl dodec-11-enylfluorophosphonate (IDFP)
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2014-12-11
Authors: Glukhova, A., Tesmer, J.J.G.
PDB entry 4x92: Crystal structure of Lysosomal Phospholipase A2-S165A
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3 Å
Deposited: 2014-12-11
Authors: Glukhova, A., Tesmer, J.J.G.
PDB entry 4x93: Crystal structure of Lysosomal Phospholipase A2 crystallized in the presence of methyl arachidonyl fluorophosphonate (tetragonal form)
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.6 Å
Deposited: 2014-12-11
Authors: Glukhova, A., Tesmer, J.J.G.
PDB entry 4x94: Crystal structure of Lysosomal Phospholipase A2 crystallized in the presence of methyl arachidonyl fluorophosphonate (hexagonal form)
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.7 Å
Deposited: 2014-12-11
Authors: Glukhova, A., Tesmer, J.J.G.
PDB entry 4x95: Crystal structure of fully glycosylated Lysosomal Phospholipase A2 in complex with methyl arachidonyl fluorophosphonate (MAFP)
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 3.08 Å
Deposited: 2014-12-11
Authors: Glukhova, A., Tesmer, J.J.G.
PDB entry 4x96: Low resolution crystal structure of Lecithin:Cholesterol Acyltransferase (LCAT; residues 21-397)
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 8.69 Å
Deposited: 2014-12-11
Authors: Glukhova, A., Tesmer, J.J.G.
PDB entry 4x97: Crystal structure of Lysosomal Phospholipase A2 in complex with methyl arachidonyl fluorophosphonate (MAFP)
Classification: TRANSFERASE
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.65 Å
Deposited: 2014-12-11
Authors: Glukhova, A., Tesmer, J.J.G.
PDB entry 4x98: Immunoglobulin Fc heterodimer variant
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.499 Å
Deposited: 2014-12-11
Authors: Seok, S.H., Choi, H.J., Kim, Y.J., Seo, M.D., Kim, Y.S.
PDB entry 4x99: Immunoglobulin Fc heterodimers variant
Classification: IMMUNE SYSTEM
Source organism: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 2.498 Å
Deposited: 2014-12-11
Authors: Seok, S.H., Choi, H.J., Kim, Y.J., Seo, M.D., Kim, Y.S.
PDB entry 4x9b: Crystal structure of Dscam1 isoform 4.44, N-terminal four Ig domains
Classification: CELL ADHESION
Source organism: Drosophila melanogaster
Experimental method: X-RAY DIFFRACTION
Resolution: 2.2 Å
Deposited: 2014-12-11
Authors: Chen, Q., Yu, Y., Li, S.A., Cheng, L.
PDB entry 4x9c: 1.4A crystal structure of Hfq from Methanococcus jannaschii
Classification: RNA BINDING PROTEIN
Source organism: Methanocaldococcus jannaschii
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4 Å
Deposited: 2014-12-11
Authors: Nikulin, A.D., Tishchenko, S.V., Nikonova, S.V., Murina, V.N., Mihailina, A.O., Lekontseva, N.V.
PDB entry 4x9d: High-resolution structure of Hfq from Methanococcus jannaschii in complex with UMP
Classification: RNA BINDING PROTEIN
Source organism: Methanocaldococcus jannaschii
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5 Å
Deposited: 2014-12-11
Authors: Nikulin, A.D., Tishchenko, S.V., Nikonova, E.Y., Murina, V.N., Mihailina, A.O., Lekontseva, N.V.
PDB entry 4x9e: DEOXYGUANOSINETRIPHOSPHATE TRIPHOSPHOHYDROLASE from Escherichia coli with two DNA effector molecules
Classification: HYDROLASE/DNA
Source organism: Escherichia coli
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1 Å
Deposited: 2014-12-11
Authors: Singh, D., Gawel, D., Itsko, M., Krahn, J.M., London, R.E., Schaaper, R.M.
PDB entry 4x9f: Crystal structure of Dscam1 isoform 6.9, N-terminal four Ig domains
Classification: CELL ADHESION
Source organism: Drosophila melanogaster
Experimental method: X-RAY DIFFRACTION
Resolution: 2.35 Å
Deposited: 2014-12-11
Authors: Chen, Q., Yu, Y., Li, S.A., Cheng, L.
PDB entry 4x9g: Crystal structure of Dscam1 isoform 6.44, N-terminal four Ig domains
Classification: CELL ADHESION
Source organism: Drosophila melanogaster
Experimental method: X-RAY DIFFRACTION
Resolution: 3.403 Å
Deposited: 2014-12-11
Authors: Chen, Q., Yu, Y., Li, S.A., Cheng, L.
PDB entry 4x9h: Crystal structure of Dscam1 isoform 8.4, N-terminal four Ig domains
Classification: CELL ADHESION
Source organism: Drosophila melanogaster
Experimental method: X-RAY DIFFRACTION
Resolution: 2.95 Å
Deposited: 2014-12-11
Authors: Chen, Q.
PDB entry 4x9i: Crystal structure of Dscam1 isoform 9.44, N-terminal four Ig domains
Classification: CELL ADHESION
Source organism: Drosophila melanogaster
Experimental method: X-RAY DIFFRACTION
Resolution: 2.904 Å
Deposited: 2014-12-11
Authors: Chen, Q., Yu, Y., Li, S.A., cheng, L.
PDB entry 4x9j: EGR-1 with Doubly Methylated DNA
Classification: Transcription Regulator/DNA
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.412 Å
Deposited: 2014-12-11
Authors: White, M.A., Zandarashvili, L., Iwahara, J.
PDB entry 4x9k: Beta-ketoacyl-acyl carrier protein synthase III-2 (FabH2)(C113A) from Vibrio cholerae
Classification: TRANSFERASE
Source organism: Vibrio cholerae serotype O1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.61 Å
Deposited: 2014-12-11
Authors: Hou, J., Chruszcz, M., Zheng, H., Grabowski, M., Chordia, M.D., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4x9l: N-terminal domain of Heat shock protein 90 from Oryza sativa
Classification: CHAPERONE
Source organism: Oryza sativa subsp. japonica
Experimental method: X-RAY DIFFRACTION
Resolution: 3.1 Å
Deposited: 2014-12-11
Authors: Raman, S., Suguna, K.
PDB entry 4x9m: Oxidized L-alpha-Glycerophosphate Oxidase from Mycoplasma pneumoniae with FAD bound
Classification: OXIDOREDUCTASE
Source organism: Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.4 Å
Deposited: 2014-12-11
Authors: Elkhal, C.K., Kean, K.M., Parsonage, D., Claiborne, A., Karplus, P.A.
PDB entry 4x9n: Dithionite reduced L-alpha-Glycerophosphate Oxidase from Mycoplasma pneumoniae with FAD bound
Classification: OXIDOREDUCTASE
Source organism: Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.499 Å
Deposited: 2014-12-11
Authors: Elkhal, C.K., Kean, K.M., Parsonage, D., Claiborne, A., Karplus, P.A.
PDB entry 4x9o: Beta-ketoacyl-ACP synthase III -2 (FabH2) (C113A) from Vibrio Cholerae soaked with octanoyl-CoA: conformational changes without clearly bound substrate
Classification: TRANSFERASE
Source organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Experimental method: X-RAY DIFFRACTION
Resolution: 2.3 Å
Deposited: 2014-12-11
Authors: Hou, J., Cooper, D.R., Shabalin, I.G., Grabowski, M., Shumilin, I., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
PDB entry 4x9p: Crystal structure of bovine Annexin A2
Classification: CALCIUM BINDING PROTEIN
Source organism: Bos taurus
Experimental method: X-RAY DIFFRACTION
Resolution: 2.01 Å
Deposited: 2014-12-11
Authors: Shumilin, I.A., Hollas, H., Vedeler, A., Kretsinger, R.H.
PDB entry 4x9q: MnSOD-3 Room Temperature Structure
Classification: OXIDOREDUCTASE
Source organism: Caenorhabditis elegans
Experimental method: X-RAY DIFFRACTION
Resolution: 1.77 Å
Deposited: 2014-12-11
Authors: Hunter, G.J., Trinh, C.H., Hunter, T., Bonetta, R., Stewart, E.E.
PDB entry 4x9r: PLK-1 polo-box domain in complex with Bioactive Imidazolium-containing phosphopeptide macrocycle 3B
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Source organism: Homo sapiens; SYNTHETIC CONSTRUCT
Experimental method: X-RAY DIFFRACTION
Resolution: 1.398 Å
Deposited: 2014-12-11
Authors: Grant, R.A., Qian, W.-J., Yaffe, M.B., Burke, T.R.
PDB entry 4x9s: CRYSTAL STRUCTURE OF HISAP FROM STREPTOMYCES SP. MG1
Classification: ISOMERASE
Source organism: Streptomyces sp. Mg1
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6 Å
Deposited: 2014-12-11
Authors: MICHALSKA, K., VERDUZCO-CASTRO, E.A., ENDRES, M., BARONA-GOMEZ, F., JOACHIMIAK, A., Midwest Center for Structural Genomics (MCSG)
PDB entry 4x9t: Crystal structure of a TctC solute binding protein from Polaromonas (Bpro_3516, Target EFI-510338), no ligand
Classification: UNKNOWN FUNCTION
Source organism: Polaromonas sp. (strain JS666 / ATCC BAA-500)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.24 Å
Deposited: 2014-12-11
Authors: Yadava, U., Vetting, M.W., Al Obaidi, N.F., Toro, R., Morisco, L.L., Benach, J., Wasserman, S.R., Attonito, J.D., Scott Glenn, A., Chamala, S., Chowdhury, S., Lafleur, J., Love, J., Seidel, R.D., Whalen, K.L., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
PDB entry 4x9u: Crystal structure of the kiwifruit allergen Act d 5
Classification: PLANT PROTEIN
Source organism: Actinidia deliciosa
Experimental method: X-RAY DIFFRACTION
Resolution: 2.1 Å
Deposited: 2014-12-11
Authors: Offermann, L.R., Perdue, M.L., Giangrieco, I., Tamburrini, M., Ciardiello, M.A., Chruszcz, M.