Reference: Jacob C Milligan; Carl W Davis; Xiaoying Yu; Philipp A Ilinykh; Kai Huang; Peter J Halfmann; Robert W Cross; Viktoriya Borisevich; Krystle N Agans; Joan B Geisbert; Chakravarthy Chennareddy; Arthur J Goff; Ashley E Piper; Sean Hui; Kelly C L Shaffer; Tierra Buck; Megan L Heinrich; Luis M Branco; Ian Crozier; Michael R Holbrook; Jens H Kuhn; Yoshihiro Kawaoka; Pamela J Glass; Alexander Bukreyev; Thomas W Geisbert; Gabriella Worwa; Rafi Ahmed; Erica Ollmann Saphire. "Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses." Cell (2022).

Epitope: Epitope of mAb 9.20.1C3 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K114, K115, P116, D117, G118, S119, E120, A124, A125, D127, R172; C: K114, P116, D117, G118, S119, E120, P123, A124, D150, R172
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 9.20.1C3 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K114, K115, P116, D117, G118, S119, E120, A124, A125, D127, R172; C: K114, P116, D117, G118, S119, E120, P123, A124, D150, R172
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb 9.20.1C3 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K114, K115, P116, D117, G118, S119, E120, A124, A125, D127, R172; C: K114, P116, D117, G118, S119, E120, P123, A124, D150, R172
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb 9.20.1C3 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K114, K115, P116, D117, G118, S119, E120, A124, A125, D127, R172; C: K114, P116, D117, G118, S119, E120, P123, A124, D150, R172
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb 9.20.1C3 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K114, K115, P116, D117, G118, S119, E120, A124, A125, D127, R172; C: K114, P116, D117, G118, S119, E120, P123, A124, D150, R172
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 9.20.1C3 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K114, K115, P116, D117, G118, S119, E120, A124, A125, D127, R172; C: K114, P116, D117, G118, S119, E120, P123, A124, D150, R172
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 9.20.1C3 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K114, K115, P116, D117, G118, S119, E120, A124, A125, D127, R172; C: K114, P116, D117, G118, S119, E120, P123, A124, D150, R172
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 9.20.1C3 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K114, K115, P116, D117, G118, S119, E120, A124, A125, D127, R172; C: K114, P116, D117, G118, S119, E120, P123, A124, D150, R172
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 9.20.1C3 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K114, K115, P116, D117, G118, S119, E120, A124, A125, D127, R172; C: K114, P116, D117, G118, S119, E120, P123, A124, D150, R172
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 9.20.1C3 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K114, K115, P116, D117, G118, S119, E120, A124, A125, D127, R172; C: K114, P116, D117, G118, S119, E120, P123, A124, D150, R172
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of mAb 9.20.1C3 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K114, K115, P116, D117, G118, S119, E120, A124, A125, D127, R172; C: K114, P116, D117, G118, S119, E120, P123, A124, D150, R172
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of mAb 9.20.1C3 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K114, K115, P116, D117, G118, S119, E120, A124, A125, D127, R172; C: K114, P116, D117, G118, S119, E120, P123, A124, D150, R172
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 9.20.1C3 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K114, K115, P116, D117, G118, S119, E120, A124, A125, D127, R172; C: K114, P116, D117, G118, S119, E120, P123, A124, D150, R172
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 9.20.1C3 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K114, K115, P116, D117, G118, S119, E120, A124, A125, D127, R172; C: K114, P116, D117, G118, S119, E120, P123, A124, D150, R172
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv 5.24.1C11 on Ebolavirus spike glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: D: E502, D522, E523, G524, I527, G528, L529, A530, W531, I532, Y534, F535, G536; E: P34, F88, R89, S90, K155
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 5.6.1A2 on Ebolavirus spike glycoprotein
Chemical type: Discontinuous protein residues
Discontinuous residues: G524, A525, I527, I532
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 5.6.1A2 on Ebolavirus spike glycoprotein
Chemical type: Discontinuous protein residues
Discontinuous residues: G524, A525, I527, I532
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G118
Chemical type: Discontinuous protein residues
Discontinuous residues: G118
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G118
Chemical type: Discontinuous protein residues
Discontinuous residues: G118
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G118
Chemical type: Discontinuous protein residues
Discontinuous residues: G118
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G118
Chemical type: Discontinuous protein residues
Discontinuous residues: G118
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G118
Chemical type: Discontinuous protein residues
Discontinuous residues: G118
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G118
Chemical type: Discontinuous protein residues
Discontinuous residues: G118
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G118
Chemical type: Discontinuous protein residues
Discontinuous residues: G118
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G118, T144
Chemical type: Discontinuous protein residues
Discontinuous residues: G118, T144
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G118, T144
Chemical type: Discontinuous protein residues
Discontinuous residues: G118, T144
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G118, T144
Chemical type: Discontinuous protein residues
Discontinuous residues: G118, T144
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G118, T144
Chemical type: Discontinuous protein residues
Discontinuous residues: G118, T144
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G118, T144
Chemical type: Discontinuous protein residues
Discontinuous residues: G118, T144
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G118, T144
Chemical type: Discontinuous protein residues
Discontinuous residues: G118, T144
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G118, T144
Chemical type: Discontinuous protein residues
Discontinuous residues: G118, T144
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G118, T144
Chemical type: Discontinuous protein residues
Discontinuous residues: G118, T144
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive-Low

Epitope: G118, T144
Chemical type: Discontinuous protein residues
Discontinuous residues: G118, T144
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G224
Chemical type: Discontinuous protein residues
Discontinuous residues: G224
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G224
Chemical type: Discontinuous protein residues
Discontinuous residues: G224
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G224
Chemical type: Discontinuous protein residues
Discontinuous residues: G224
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G224
Chemical type: Discontinuous protein residues
Discontinuous residues: G224
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G224
Chemical type: Discontinuous protein residues
Discontinuous residues: G224
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G224
Chemical type: Discontinuous protein residues
Discontinuous residues: G224
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive-Low

Epitope: G224
Chemical type: Discontinuous protein residues
Discontinuous residues: G224
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: G224
Chemical type: Discontinuous protein residues
Discontinuous residues: G224
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: I532
Chemical type: Discontinuous protein residues
Discontinuous residues: I532
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: I532
Chemical type: Discontinuous protein residues
Discontinuous residues: I532
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: I532
Chemical type: Discontinuous protein residues
Discontinuous residues: I532
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive-Low

Epitope: I532
Chemical type: Discontinuous protein residues
Discontinuous residues: I532
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: I532
Chemical type: Discontinuous protein residues
Discontinuous residues: I532
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: I532
Chemical type: Discontinuous protein residues
Discontinuous residues: I532
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: I532
Chemical type: Discontinuous protein residues
Discontinuous residues: I532
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive

Epitope: I532
Chemical type: Discontinuous protein residues
Discontinuous residues: I532
Source molecule (GenBank): ALG01342.1
Assay category: BCell
Result: Positive