Reference: J T Gerlach; A Ulsenheimer; N H Grüner; M-C Jung; W Schraut; C-A Schirren; M Heeg; S Scholz; K Witter; R Zahn; A Vogler; R Zachoval; G R Pape; H M Diepolder. "Minimal T-cell-stimulatory sequences and spectrum of HLA restriction of immunodominant CD4+ T-cell epitopes within hepatitis C virus NS3 and NS4 proteins." Journal of virology (2005).

Epitope: p5
Chemical type: Peptide from protein
Sequence: AAYAAQGYKVLVLNPSVAAT
Position: 1242-1261
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: p22
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKKKCDELATKL
Position: 1388-1407
Source molecule (GenBank): BAD91386.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: p24
Chemical type: Peptide from protein
Sequence: KLVAMGINAVAYYRGLDVSV
Position: 1406-1425
Source molecule (GenBank): AAY82027.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: p29
Chemical type: Peptide from protein
Sequence: SVIDCNTCVTQTVDFSLDPT
Position: 1450-1469
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: p37
Chemical type: Peptide from protein
Sequence: TTVRLRAYMNTPGLPVCQDH
Position: 1535-1554
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: p41
Chemical type: Peptide from protein
Sequence: QTKQSGENLPYLVAYQATVC
Position: 1125-1144
Source molecule (GenBank): AAA45677.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: p42
Chemical type: Peptide from protein
Sequence: YLVAYQATVCARAQAPPPSW
Position: 1585-1604
Source molecule (GenBank): BAD91386.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P60
Chemical type: Peptide from protein
Sequence: MWNFISGIQYLAGLSTLPGN
Position: 1770-1789
Source molecule (GenBank): AAU89634.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: p61
Chemical type: Peptide from protein
Sequence: LAGLSTLPGNPAIASLMAFT
Position: 1775-1794
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: p64
Chemical type: Peptide from protein
Sequence: QTLLFNILGGWVAAQLAAPG
Position: 1805-1824
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: p74
Chemical type: Peptide from protein
Sequence: HVGPGEGAVQWMNRLIAFAS
Position: 1905-1924
Source molecule (GenBank): BAB18806.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: p79
Chemical type: Peptide from protein
Sequence: QLLRRLHQWISSECTTPCSG
Position: 1955-1974
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: p22.1388-1398
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKR
Position: 1388-1398
Source molecule (GenBank): AAY82032.1
Assay category: TCell
Result: Positive
MHC allele types: 436 437
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: p24.1415-1425
Chemical type: Peptide from protein
Sequence: VAYYRGLDVSV
Position: 1415-1425
Source molecule (GenBank): AAY82027.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p37.1540-1550
Chemical type: Peptide from protein
Sequence: RAYMNTPGLPV
Position: 1540-1550
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p37.1539-1550
Chemical type: Peptide from protein
Sequence: LRAYMNTPGLPV
Position: 1539-1550
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: p42.1585-1595
Chemical type: Peptide from protein
Sequence: YLVAYQATVCA
Position: 1585-1595
Source molecule (GenBank): BAD91386.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p42.1582-1595
Chemical type: Peptide from protein
Sequence: NLPYLVAYQATVCA
Position: 1132-1145
Source molecule (GenBank): AAA45677.1
Assay category: TCell
Result: Positive
MHC allele types: 52 56
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: p49.1659-1668
Chemical type: Peptide from protein
Sequence: TWVLVGGVLA
Position: 1659-1668
Source molecule (GenBank): AAA86907.1
Assay category: TCell
Result: Positive
MHC allele types: 413 52
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p49.1657-1669
Chemical type: Peptide from protein
Sequence: TSTWVLVGGVLAA
Position: 1657-1669
Source molecule (GenBank): AAA86907.1
Assay category: TCell
Result: Positive
MHC allele types: 413 52
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: p52.1690-1704
Chemical type: Peptide from protein
Sequence: GKPAIIPDREVLYRE
Position: 1240-1254
Source molecule (GenBank): AAA45677.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p52.1694-1703
Chemical type: Peptide from protein
Sequence: IIPDREVLYR
Position: 1244-1253
Source molecule (GenBank): AAA45677.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P60.1773-1783
Chemical type: Peptide from protein
Sequence: QYLAGLSTLPGN
Position: 1778-1789
Source molecule (GenBank): AAU89634.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p62.1787-1796
Chemical type: Peptide from protein
Sequence: IASLMAFTAA
Position: 1787-1796
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p64.1808-1817
Chemical type: Peptide from protein
Sequence: LFNILGGWVA
Position: 1808-1817
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p64.1809-1820
Chemical type: Peptide from protein
Sequence: FNILGGWVAAQL
Position: 1809-1820
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: p71.1879-1888
Chemical type: Peptide from protein
Sequence: LVNLLPAILS
Position: 1879-1888
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p71.1881-1887
Chemical type: Peptide from protein
Sequence: NLLPAIL
Position: 1881-1887
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo