Reference: Annemieke de Jong; Sjoerd H van der Burg; Kitty M C Kwappenberg; Jeanette M van der Hulst; Kees L M C Franken; Annemieke Geluk; Krista E van Meijgaarden; Jan Wouter Drijfhout; Gemma Kenter; Pieter Vermeij; Cornelis J M Melief; Rienk Offringa. "Frequent detection of human papillomavirus 16 E2-specific T-helper immunity in healthy subjects." Cancer research (2002).

Epitope: HPV16 E2<sub>271-300</sub>
Chemical type: Peptide from protein
Sequence: FNSSHKGRINCNSNTTPIVHLKGDANTLKC
Position: 271-300
Source molecule (GenBank): ACS92695.1
Assay category: TCell
Result: Positive
MHC allele types: 339 349
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV16 E2<sub>271-300</sub>
Chemical type: Peptide from protein
Sequence: FNSSHKGRINCNSNTTPIVHLKGDANTLKC
Position: 271-300
Source molecule (GenBank): ACS92695.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 65000.0

Epitope: HPV16 E2<sub>271-300</sub>
Chemical type: Peptide from protein
Sequence: FNSSHKGRINCNSNTTPIVHLKGDANTLKC
Position: 271-300
Source molecule (GenBank): ACS92695.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 37000.0

Epitope: HPV16 E2<sub>271-300</sub>
Chemical type: Peptide from protein
Sequence: FNSSHKGRINCNSNTTPIVHLKGDANTLKC
Position: 271-300
Source molecule (GenBank): ACS92695.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 70000.0

Epitope: HPV16 E2<sub>271-300</sub>
Chemical type: Peptide from protein
Sequence: FNSSHKGRINCNSNTTPIVHLKGDANTLKC
Position: 271-300
Source molecule (GenBank): ACS92695.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 22000.0

Epitope: HPV16 E2<sub>301-330</sub>
Chemical type: Peptide from protein
Sequence: LRYRFKKHCTLYTAVSSTWHWTGHNVKHKS
Position: 301-330
Source molecule (GenBank): P03120.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV16 E2<sub>301-330</sub>
Chemical type: Peptide from protein
Sequence: LRYRFKKHCTLYTAVSSTWHWTGHNVKHKS
Position: 301-330
Source molecule (GenBank): P03120.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV16 E2<sub>301-330</sub>
Chemical type: Peptide from protein
Sequence: LRYRFKKHCTLYTAVSSTWHWTGHNVKHKS
Position: 301-330
Source molecule (GenBank): P03120.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 8000.0

Epitope: HPV16 E2<sub>301-330</sub>
Chemical type: Peptide from protein
Sequence: LRYRFKKHCTLYTAVSSTWHWTGHNVKHKS
Position: 301-330
Source molecule (GenBank): P03120.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 6000.0

Epitope: HPV16 E2<sub>301-330</sub>
Chemical type: Peptide from protein
Sequence: LRYRFKKHCTLYTAVSSTWHWTGHNVKHKS
Position: 301-330
Source molecule (GenBank): P03120.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 70000.0

Epitope: HPV16 E2<sub>301-330</sub>
Chemical type: Peptide from protein
Sequence: LRYRFKKHCTLYTAVSSTWHWTGHNVKHKS
Position: 301-330
Source molecule (GenBank): P03120.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10000.0

Epitope: HPV16 E2<sub>316-345</sub>
Chemical type: Peptide from protein
Sequence: SSTWHWTGHNVKHKSAIVTLTYDSEWQRDQ
Position: 316-345
Source molecule (GenBank): P03120.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV16 E2<sub>316-345</sub>
Chemical type: Peptide from protein
Sequence: SSTWHWTGHNVKHKSAIVTLTYDSEWQRDQ
Position: 316-345
Source molecule (GenBank): P03120.1
Assay category: TCell
Result: Positive
MHC allele types: 327 341
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV16 E2<sub>316-345</sub>
Chemical type: Peptide from protein
Sequence: SSTWHWTGHNVKHKSAIVTLTYDSEWQRDQ
Position: 316-345
Source molecule (GenBank): P03120.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 6000.0

Epitope: HPV16 E2<sub>316-345</sub>
Chemical type: Peptide from protein
Sequence: SSTWHWTGHNVKHKSAIVTLTYDSEWQRDQ
Position: 316-345
Source molecule (GenBank): P03120.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 55000.0

Epitope: HPV16 E2<sub>316-345</sub>
Chemical type: Peptide from protein
Sequence: SSTWHWTGHNVKHKSAIVTLTYDSEWQRDQ
Position: 316-345
Source molecule (GenBank): P03120.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 30000.0

Epitope: HPV16 E2<sub>316-345</sub>
Chemical type: Peptide from protein
Sequence: SSTWHWTGHNVKHKSAIVTLTYDSEWQRDQ
Position: 316-345
Source molecule (GenBank): P03120.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 70000.0

Epitope: HPV16 E2<sub>331-365</sub>
Chemical type: Peptide from protein
Sequence: AIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI
Position: 331-365
Source molecule (GenBank): P03120.1
Assay category: TCell
Result: Positive
MHC allele types: 327 340 341
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV16 E2<sub>331-365</sub>
Chemical type: Peptide from protein
Sequence: AIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI
Position: 331-365
Source molecule (GenBank): P03120.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV16 E2<sub>331-365</sub>
Chemical type: Peptide from protein
Sequence: AIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI
Position: 331-365
Source molecule (GenBank): P03120.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 8000.0

Epitope: HPV16 E2<sub>331-365</sub>
Chemical type: Peptide from protein
Sequence: AIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI
Position: 331-365
Source molecule (GenBank): P03120.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 20000.0

Epitope: HPV16 E2<sub>331-365</sub>
Chemical type: Peptide from protein
Sequence: AIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI
Position: 331-365
Source molecule (GenBank): P03120.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10000.0

Epitope: HPV16 E2<sub>331-365</sub>
Chemical type: Peptide from protein
Sequence: AIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI
Position: 331-365
Source molecule (GenBank): P03120.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 15000.0

Epitope: HPV16 E2<sub>316-330</sub>
Chemical type: Peptide from protein
Sequence: SSTWHWTGHNVKHKS
Position: 316-330
Source molecule (GenBank): ACS92695.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV16 E2<sub>311-325</sub>
Chemical type: Peptide from protein
Sequence: LYTAVSSTWHWTGHN
Position: 311-325
Source molecule (GenBank): ACS92695.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV16 E2<sub>311-325</sub>
Chemical type: Peptide from protein
Sequence: LYTAVSSTWHWTGHN
Position: 311-325
Source molecule (GenBank): ACS92695.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV16 E2<sub>311-325</sub>
Chemical type: Peptide from protein
Sequence: LYTAVSSTWHWTGHN
Position: 311-325
Source molecule (GenBank): ACS92695.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV16 E2<sub>311-325</sub>
Chemical type: Peptide from protein
Sequence: LYTAVSSTWHWTGHN
Position: 311-325
Source molecule (GenBank): ACS92695.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV16 E2<sub>311-325</sub>
Chemical type: Peptide from protein
Sequence: LYTAVSSTWHWTGHN
Position: 311-325
Source molecule (GenBank): ACS92695.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV16 E2<sub>346-355</sub>
Chemical type: Peptide from protein
Sequence: FLSQVKIPKT
Position: 346-355
Source molecule (GenBank): ACS92695.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV16 E2<sub>351-365</sub>
Chemical type: Peptide from protein
Sequence: KIPKTITVSTGFMSI
Position: 351-365
Source molecule (GenBank): ACS92695.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV 26 E2 peptide
Chemical type: Peptide from protein
Sequence: LYCNVSSTWHWTSND
Position: 322-336
Source molecule (GenBank): NP_041785.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV 31 E2 peptide
Chemical type: Peptide from protein
Sequence: LYEQVSSTWHWTCTD
Position: 318-332
Source molecule (GenBank): P17383.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV 33 E2 peptide
Chemical type: Peptide from protein
Sequence: LYSSMSSTWHWTSDN
Position: 299-313
Source molecule (GenBank): P06423.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV 45 E2 peptide
Chemical type: Peptide from protein
Sequence: HYSEISSTWHWTGCN
Position: 316-330
Source molecule (GenBank): ABP99851.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Cell Line / Clone