Reference: A A Manfredi; M P Protti; X D Wu; J F Howard; B M Conti-Tronconi. "CD4+ T-epitope repertoire on the human acetylcholine receptor alpha subunit in severe myasthenia gravis: a study with synthetic peptides." Neurology (1992).

Epitope: Hα1-14
Chemical type: Peptide from protein
Sequence: SEHETRLVAKLFKD
Position: 21-34
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα19-34
Chemical type: Peptide from protein
Sequence: VRPVEDHRQVVEVTVG
Position: 39-54
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα32-51
Chemical type: Peptide from protein
Sequence: TVGLQLIQLINVDEVNQIVT
Position: 52-71
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα48-67
Chemical type: Peptide from protein
Sequence: QIVTTNVRLKQQWVDYNLKW
Position: 68-87
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα63-80
Chemical type: Peptide from protein
Sequence: YNLKWNPDDYGGVKKIHI
Position: 83-100
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα89-105
Chemical type: Peptide from protein
Sequence: DLVLYNNADGDFAIVK
Position: 109-124
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα118-137
Chemical type: Peptide from protein
Sequence: WTPPAIFKSYCEIIVTHFPF
Position: 138-157
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα135-154
Chemical type: Peptide from protein
Sequence: FPFDEQNCSMKLGTWTYDGS
Position: 155-174
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα151-168
Chemical type: Peptide from protein
Sequence: YDGSVVAINPESDQPDLS
Position: 171-188
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα166-185
Chemical type: Peptide from protein
Sequence: DLSNFMESGEWVIKESRGWK
Position: 186-205
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα181-195
Chemical type: Peptide from protein
Sequence: SRGWKHSVTYSCCPDTPY
Position: 201-218
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα191-207
Chemical type: Peptide from protein
Sequence: SCCPDTPYLDITYHFVM
Position: 211-227
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα203-218
Chemical type: Peptide from protein
Sequence: YHFVMQRLPLYFIVNV
Position: 223-238
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα214-234
Chemical type: Peptide from protein
Sequence: FIVNVIIPCLLFSFLTGLVFY
Position: 234-254
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα230-249
Chemical type: Peptide from protein
Sequence: GLVFYLPTDSGEKMTLSISV
Position: 250-269
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα246-264
Chemical type: Peptide from protein
Sequence: SISVLLSLTVFLLVIVELI
Position: 266-284
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα261-280
Chemical type: Peptide from protein
Sequence: IVELIPSTSSAVPLIGKYMLF
Position: 280-300
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα280-297
Chemical type: Peptide from protein
Sequence: FTMVFVIASIIITVIVIN
Position: 300-317
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα293-308
Chemical type: Peptide from protein
Sequence: VIVINTHHRSPSTHVM
Position: 313-328
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα304-322
Chemical type: Peptide from protein
Sequence: STHVMPNWVRKVFIDTIPNIMF
Position: 324-345
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα320-337
Chemical type: Peptide from protein
Sequence: IPNIMFFSTMKRPSREKQ
Position: 340-357
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα329-347
Chemical type: Peptide from protein
Sequence: MKRPSREKQDKKIFTEDID
Position: 349-367
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα343-356
Chemical type: Peptide from protein
Sequence: TEDIDISDISGKPG
Position: 363-376
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα352-368
Chemical type: Peptide from protein
Sequence: SGKPGPPPMGFHSPLIK
Position: 372-388
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα364-380
Chemical type: Peptide from protein
Sequence: HSPLIKHFEVKSAIEGIK
Position: 383-400
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα376-393
Chemical type: Peptide from protein
Sequence: IEGIKYIAETMKSDQESN
Position: 396-413
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα387-405
Chemical type: Peptide from protein
Sequence: KSDQESNNAAAEWKYVAM
Position: 407-424
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα403-421
Chemical type: Peptide from protein
Sequence: AMVMDHILLGVFMLVCIIG
Position: 423-441
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Hα419-437
Chemical type: Peptide from protein
Sequence: IIGTLAVFAGRLIELNQQG
Position: 439-457
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Host:  21-41 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo