Reference: R Raju; S R Munn; C S David. "T cell recognition of human pre-proinsulin peptides depends on the polymorphism at HLA DQ locus: a study using HLA DQ8 and DQ6 transgenic mice." Human immunology (1997).

Epitope: HPI 1-24
Chemical type: Peptide from protein
Sequence: MALWMRLLPLLALLALWGPDPAAA
Position: 1-24
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-Low
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 1-24
Chemical type: Peptide from protein
Sequence: MALWMRLLPLLALLALWGPDPAAA
Position: 1-24
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-High
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 1-24
Chemical type: Peptide from protein
Sequence: MALWMRLLPLLALLALWGPDPAAA
Position: 1-24
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 1-24
Chemical type: Peptide from protein
Sequence: MALWMRLLPLLALLALWGPDPAAA
Position: 1-24
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 14-33
Chemical type: Peptide from protein
Sequence: LALWGPDPAAAFVNQHLCGS
Position: 14-33
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-Low
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 14-33
Chemical type: Peptide from protein
Sequence: LALWGPDPAAAFVNQHLCGS
Position: 14-33
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-High
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 14-33
Chemical type: Peptide from protein
Sequence: LALWGPDPAAAFVNQHLCGS
Position: 14-33
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 14-33
Chemical type: Peptide from protein
Sequence: LALWGPDPAAAFVNQHLCGS
Position: 14-33
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 24-43
Chemical type: Peptide from protein
Sequence: AFVNQHLCGSHLVEALYLVC
Position: 24-43
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 24-43
Chemical type: Peptide from protein
Sequence: AFVNQHLCGSHLVEALYLVC
Position: 24-43
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 24-43
Chemical type: Peptide from protein
Sequence: AFVNQHLCGSHLVEALYLVC
Position: 24-43
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 24-43
Chemical type: Peptide from protein
Sequence: AFVNQHLCGSHLVEALYLVC
Position: 24-43
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 34-53
Chemical type: Peptide from protein
Sequence: HLVEALYLVCGERGFFYTPK
Position: 34-53
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-Low
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 34-53
Chemical type: Peptide from protein
Sequence: HLVEALYLVCGERGFFYTPK
Position: 34-53
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-Low
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 44-63
Chemical type: Peptide from protein
Sequence: GERGFFYTPKTRREAEDLQV
Position: 44-63
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-High
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 44-63
Chemical type: Peptide from protein
Sequence: GERGFFYTPKTRREAEDLQV
Position: 44-63
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 44-63
Chemical type: Peptide from protein
Sequence: GERGFFYTPKTRREAEDLQV
Position: 44-63
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 44-63
Chemical type: Peptide from protein
Sequence: GERGFFYTPKTRREAEDLQV
Position: 44-63
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 64-83
Chemical type: Peptide from protein
Sequence: GQVELGGGPGAGSLQPLALE
Position: 64-83
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 64-83
Chemical type: Peptide from protein
Sequence: GQVELGGGPGAGSLQPLALE
Position: 64-83
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-Low
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 64-83
Chemical type: Peptide from protein
Sequence: GQVELGGGPGAGSLQPLALE
Position: 64-83
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-Low
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 64-83
Chemical type: Peptide from protein
Sequence: GQVELGGGPGAGSLQPLALE
Position: 64-83
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 74-93
Chemical type: Peptide from protein
Sequence: AGSLQPLALEGSLQKRGIVE
Position: 74-93
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 74-93
Chemical type: Peptide from protein
Sequence: AGSLQPLALEGSLQKRGIVE
Position: 74-93
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-Low
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 74-93
Chemical type: Peptide from protein
Sequence: AGSLQPLALEGSLQKRGIVE
Position: 74-93
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-High
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 74-93
Chemical type: Peptide from protein
Sequence: AGSLQPLALEGSLQKRGIVE
Position: 74-93
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 84-103
Chemical type: Peptide from protein
Sequence: GSLQKRGIVEQCCTSICSLY
Position: 84-103
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 84-103
Chemical type: Peptide from protein
Sequence: GSLQKRGIVEQCCTSICSLY
Position: 84-103
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 84-103
Chemical type: Peptide from protein
Sequence: GSLQKRGIVEQCCTSICSLY
Position: 84-103
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 84-103
Chemical type: Peptide from protein
Sequence: GSLQKRGIVEQCCTSICSLY
Position: 84-103
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 94-110
Chemical type: Peptide from protein
Sequence: QCCTSICSLYQLENYCN
Position: 94-110
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HPI 94-110
Chemical type: Peptide from protein
Sequence: QCCTSICSLYQLENYCN
Position: 94-110
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-Low
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M1 I 1-24
Chemical type: Peptide from protein
Sequence: MALLVHFLPLLALLALWEPKPTQA
Position: 1-24
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M1 I 14-33
Chemical type: Peptide from protein
Sequence: LALWEPKPTQAFVKQHLCGP
Position: 14-33
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M1 I 24-43
Chemical type: Peptide from protein
Sequence: AFVKQHLCGPHLVEALYLVC
Position: 24-43
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M1 I 44-63
Chemical type: Peptide from protein
Sequence: GERGFFYTPKSRREVEDPQV
Position: 44-63
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M1 I 54-73
Chemical type: Peptide from protein
Sequence: SRREVEDPQVEQLELGGSPG
Position: 54-73
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M1 I 64-83
Chemical type: Peptide from protein
Sequence: EQLELGGSPGDLQTLALEVA
Position: 64-83
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M1 I 84-103
Chemical type: Peptide from protein
Sequence: VARQKRGIVDQCCTSICSLY
Position: 82-101
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M2 I 1-24
Chemical type: Peptide from protein
Sequence: MALWMRFLPLLALLFLWESHPTQA
Position: 1-24
Source molecule (GenBank): CAA28433.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M2 I 24-33
Chemical type: Peptide from protein
Sequence: AFVKQHLCGSHLVEALYLVC
Position: 24-43
Source molecule (GenBank): CAA28433.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M2 I 44-63
Chemical type: Peptide from protein
Sequence: GERGFFYTPMSRREVEDPQV
Position: 44-63
Source molecule (GenBank): CAA28433.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M2 I 54-73
Chemical type: Peptide from protein
Sequence: SRREVEDPQVAQLELGGGPG
Position: 54-73
Source molecule (GenBank): CAA28433.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M2 I 64-83
Chemical type: Peptide from protein
Sequence: AQLELGGGPGAGDLQTLALE
Position: 64-83
Source molecule (GenBank): CAA28433.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M2 I 84-103
Chemical type: Peptide from protein
Sequence: VAQQKRGIVDQCCTSICSLY
Position: 84-103
Source molecule (GenBank): CAA28433.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo