Reference: Philippe Halbout; Jean-Paul Briand; Chantal Bécourt; Sylviane Muller; Christian Boitard. "T cell response to preproinsulin I and II in the nonobese diabetic mouse." Journal of immunology (Baltimore, Md. : 1950) (2002).

Epitope: I<sub>1-15</sub>
Chemical type: Peptide from protein
Sequence: MALLVHFLPLLALLA
Position: 1-15
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: I<sub>7-23</sub>
Chemical type: Peptide from protein
Sequence: FLPLLALLALWEPKPTQ
Position: 7-23
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: I<sub>7-23</sub>
Chemical type: Peptide from protein
Sequence: FLPLLALLALWEPKPTQ
Position: 7-23
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: I<sub>14-30</sub>
Chemical type: Peptide from protein
Sequence: LALWEPKPTQAFVKQHL
Position: 14-30
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: I<sub>20-35</sub>
Chemical type: Peptide from protein
Sequence: KPTQAFVKQHLCGPHL
Position: 20-35
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: I<sub>20-35</sub>
Chemical type: Peptide from protein
Sequence: KPTQAFVKQHLCGPHL
Position: 20-35
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: I<sub>20-35</sub>
Chemical type: Peptide from protein
Sequence: KPTQAFVKQHLCGPHL
Position: 20-35
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: I<sub>20-35</sub>
Chemical type: Peptide from protein
Sequence: KPTQAFVKQHLCGPHL
Position: 20-35
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: I<sub>26-41</sub>
Chemical type: Peptide from protein
Sequence: VKQHLCGPHLVEALYL
Position: 26-41
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: I<sub>33-47</sub>
Chemical type: Peptide from protein
Sequence: PHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Positive-High
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: I<sub>33-47</sub>
Chemical type: Peptide from protein
Sequence: PHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Positive
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: I<sub>33-47</sub>
Chemical type: Peptide from protein
Sequence: PHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: I<sub>46-60</sub>
Chemical type: Peptide from protein
Sequence: RGFFYTPKSRREVED
Position: 46-60
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: I<sub>50-65</sub>
Chemical type: Peptide from protein
Sequence: YTPKSRREVEDPQVEQ
Position: 50-65
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: I<sub>56-71</sub>
Chemical type: Peptide from protein
Sequence: REVEDPQVEQLELGGS
Position: 56-71
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: I<sub>61-76</sub>
Chemical type: Peptide from protein
Sequence: PQVEQLELGGSPGDLQ
Position: 61-76
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: I<sub>71-86</sub>
Chemical type: Peptide from protein
Sequence: SPGDLQTLALEVARQK
Position: 71-86
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Positive
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: I<sub>71-86</sub>
Chemical type: Peptide from protein
Sequence: SPGDLQTLALEVARQK
Position: 71-86
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: I<sub>71-86</sub>
Chemical type: Peptide from protein
Sequence: SPGDLQTLALEVARQK
Position: 71-86
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Positive-Intermediate
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: I<sub>77-92</sub>
Chemical type: Peptide from protein
Sequence: TLALEVARQKRGIVDQ
Position: 77-92
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: I<sub>77-92</sub>
Chemical type: Peptide from protein
Sequence: TLALEVARQKRGIVDQ
Position: 77-92
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: I<sub>86-101</sub>
Chemical type: Peptide from protein
Sequence: KRGIVDQCCTSICSLY
Position: 86-101
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: I<sub>91-108</sub>
Chemical type: Peptide from protein
Sequence: DQCCTSICSLYQLENYCN
Position: 91-108
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: II<sub>1-15</sub>
Chemical type: Peptide from protein
Sequence: MALWMRFLPLLALLF
Position: 1-15
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: II<sub>7-23</sub>
Chemical type: Peptide from protein
Sequence: FLPLLALLFLWESHPTQ
Position: 7-23
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: II<sub>14-30</sub>
Chemical type: Peptide from protein
Sequence: LFLWESHPTQAFVKQHL
Position: 14-30
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: II<sub>14-30</sub>
Chemical type: Peptide from protein
Sequence: LFLWESHPTQAFVKQHL
Position: 14-30
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: II<sub>20-35</sub>
Chemical type: Peptide from protein
Sequence: HPTQAFVKQHLCGSHL
Position: 20-35
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: II<sub>26-41</sub>
Chemical type: Peptide from protein
Sequence: VKQHLCGSHLVEALYL
Position: 26-41
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Positive-High
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: II<sub>26-41</sub>
Chemical type: Peptide from protein
Sequence: VKQHLCGSHLVEALYL
Position: 26-41
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Positive
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: II<sub>26-41</sub>
Chemical type: Peptide from protein
Sequence: VKQHLCGSHLVEALYL
Position: 26-41
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: II<sub>33-47</sub>
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Positive
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: II<sub>33-47</sub>
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Positive-High
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: II<sub>33-47</sub>
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: II<sub>33-47</sub>
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: II<sub>33-47</sub>
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: II<sub>40-56</sub>
Chemical type: Peptide from protein
Sequence: YLVCGERGFFYTPMSRR
Position: 40-56
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: II<sub>46-60</sub>
Chemical type: Peptide from protein
Sequence: RGFFYTPMSRREVED
Position: 46-60
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: II<sub>50-65</sub>
Chemical type: Peptide from protein
Sequence: YTPMSRREVEDPQVAQ
Position: 50-65
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: II<sub>56-71</sub>
Chemical type: Peptide from protein
Sequence: REVEDPQVAQLELGGG
Position: 56-71
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: II<sub>66-83</sub>
Chemical type: Peptide from protein
Sequence: LELGGGPGAGDLQTLALE
Position: 66-83
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: II<sub>71-88</sub>
Chemical type: Peptide from protein
Sequence: GPGAGDLQTLALEVAQQK
Position: 71-88
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: II<sub>71-88</sub>
Chemical type: Peptide from protein
Sequence: GPGAGDLQTLALEVAQQK
Position: 71-88
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: II<sub>88-103</sub>
Chemical type: Peptide from protein
Sequence: KRGIVDQCCTSICSLY
Position: 88-103
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: II<sub>93-110</sub>
Chemical type: Peptide from protein
Sequence: DQCCTSICSLYQLENYCN
Position: 93-110
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 14 weeks
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo