Reference: Zhening Zhang; Wenguang G Liang; Lucas J Bailey; Yong Zi Tan; Hui Wei; Andrew Wang; Mara Farcasanu; Virgil A Woods; Lauren A McCord; David Lee; Weifeng Shang; Rebecca Deprez-Poulain; Benoit Deprez; David R Liu; Akiko Koide; Shohei Koide; Anthony A Kossiakoff; Sheng Li; Bridget Carragher; Clinton S Potter; Wei-Jen Tang. "Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme." eLife (2018).

Epitope: Epitope of Fab H11-E on human insulin degrading enzyme (IDE)
Chemical type: Discontinuous protein residues
Discontinuous residues: L301, K303, L385, H386, V387, E388, D389, L392, I480, K501, E503, P506, E508, V509, K511, K512, D517
Source molecule (GenBank): P14735.4
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab H11-E on human insulin degrading enzyme (IDE)
Chemical type: Discontinuous protein residues
Discontinuous residues: L301, K303, L385, H386, V387, E388, D389, L392, I480, K501, E503, P506, E508, V509, K511, K512, D517
Source molecule (GenBank): P14735.4
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab H11-E on human insulin degrading enzyme (IDE)
Chemical type: Discontinuous protein residues
Discontinuous residues: L301, K303, L385, H386, V387, E388, D389, L392, I480, K501, E503, P506, E508, V509, K511, K512, D517
Source molecule (GenBank): P14735.4
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab H11-E on human insulin degrading enzyme (IDE)
Chemical type: Discontinuous protein residues
Discontinuous residues: L301, K303, L385, H386, V387, E388, D389, L392, I480, K501, E503, P506, E508, V509, K511, K512, D517
Source molecule (GenBank): P14735.4
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab H11-E on human insulin degrading enzyme (IDE)
Chemical type: Discontinuous protein residues
Discontinuous residues: L301, K303, L385, H386, V387, E388, D389, L392, I480, K501, E503, P506, E508, V509, K511, K512, D517
Source molecule (GenBank): P14735.4
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab H11-E on human insulin degrading enzyme (IDE)
Chemical type: Discontinuous protein residues
Discontinuous residues: L301, K303, L385, H386, V387, E388, D389, L392, I480, K501, E503, P506, E508, V509, K511, K512, D517
Source molecule (GenBank): P14735.4
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab H11-E on human insulin degrading enzyme (IDE)
Chemical type: Discontinuous protein residues
Discontinuous residues: L301, K303, L385, H386, V387, E388, D389, L392, I480, K501, E503, P506, E508, V509, K511, K512, D517
Source molecule (GenBank): P14735.4
Assay category: BCell
Result: Positive
Quantitative measurement: 1.0

Epitope: Epitope of Fab H11-E on human insulin degrading enzyme (IDE)
Chemical type: Discontinuous protein residues
Discontinuous residues: L301, K303, L385, H386, V387, E388, D389, L392, I480, K501, E503, P506, E508, V509, K511, K512, D517
Source molecule (GenBank): P14735.4
Assay category: BCell
Result: Positive
Quantitative measurement: 3.8

Epitope: Epitope of Fab H11-E on human insulin degrading enzyme (IDE)
Chemical type: Discontinuous protein residues
Discontinuous residues: L301, K303, L385, H386, V387, E388, D389, L392, I480, K501, E503, P506, E508, V509, K511, K512, D517
Source molecule (GenBank): P14735.4
Assay category: BCell
Result: Positive
Quantitative measurement: 160000.0

Epitope: Epitope of Fab H11-E on human insulin degrading enzyme (IDE)
Chemical type: Discontinuous protein residues
Discontinuous residues: L301, K303, L385, H386, V387, E388, D389, L392, I480, K501, E503, P506, E508, V509, K511, K512, D517
Source molecule (GenBank): P14735.4
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00011

Epitope: Epitope of  Fab1 on human insulin degrading enzyme (IDE)
Chemical type: Discontinuous protein residues
Discontinuous residues: K324, Y325, R402, A403, G405, P406, E458, F459, R460, P461, D462, L463, E465, M466, D469
Source molecule (GenBank): P14735.4
Assay category: BCell
Result: Positive
Quantitative measurement: 3.287

Epitope: Epitope of  Fab1 on human insulin degrading enzyme (IDE)
Chemical type: Discontinuous protein residues
Discontinuous residues: K324, Y325, R402, A403, G405, P406, E458, F459, R460, P461, D462, L463, E465, M466, D469
Source molecule (GenBank): P14735.4
Assay category: BCell
Result: Positive
Quantitative measurement: 3.95

Epitope: Epitope of  Fab1 on human insulin degrading enzyme (IDE)
Chemical type: Discontinuous protein residues
Discontinuous residues: K324, Y325, R402, A403, G405, P406, E458, F459, R460, P461, D462, L463, E465, M466, D469
Source molecule (GenBank): P14735.4
Assay category: BCell
Result: Positive
Quantitative measurement: 3.5007