Reference: Siri Amanda Tvingsholm; Marcus Svensson Frej; Vibeke Mindahl Rafa; Ulla Kring Hansen; Maria Ormhøj; Alexander Tyron; Agnete W P Jensen; Mohammad Kadivar; Amalie Kai Bentzen; Kamilla K Munk; Gitte N Aasbjerg; Jeppe S H Ternander; Christina Heeke; Tripti Tamhane; Christian Schmess; Samuel A Funt; Julie Westerlin Kjeldsen; Anders Handrup Kverneland; Özcan Met; Arianna Draghi; Søren Nyboe Jakobsen; Marco Donia; Inge Marie Svane; Sine Reker Hadrup. "TCR-engaging scaffolds selectively expand antigen-specific T-cells with a favorable phenotype for adoptive cell therapy." Journal for immunotherapy of cancer (2023).

Epitope: CMV pp65 YSE
Chemical type: Peptide from protein
Sequence: YSEHPTFTSQY
Position: 363-373
Source molecule (GenBank): ADV04400.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CMV pp65 YSE
Chemical type: Peptide from protein
Sequence: YSEHPTFTSQY
Position: 363-373
Source molecule (GenBank): ADV04400.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Influenza BP VSD
Chemical type: Peptide from protein
Sequence: VSDGGPNLY
Position: 591-599
Source molecule (GenBank): AWH12442.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: EBV BRLF1 YVL
Chemical type: Peptide from protein
Sequence: YVLDHLIVV
Position: 109-117
Source molecule (GenBank): P03209.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: EBV BRLF1 YVL
Chemical type: Peptide from protein
Sequence: YVLDHLIVV
Position: 109-117
Source molecule (GenBank): P03209.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: EBV BRLF1 YVL
Chemical type: Peptide from protein
Sequence: YVLDHLIVV
Position: 109-117
Source molecule (GenBank): P03209.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: EBV BRLF1 YVL
Chemical type: Peptide from protein
Sequence: YVLDHLIVV
Position: 109-117
Source molecule (GenBank): P03209.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: EBV BRLF1 YVL
Chemical type: Peptide from protein
Sequence: YVLDHLIVV
Position: 109-117
Source molecule (GenBank): P03209.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CMV pp65 NLV
Chemical type: Peptide from protein
Sequence: NLVPMVATV
Position: 495-503
Source molecule (GenBank): ADV04400.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CMV pp65 NLV
Chemical type: Peptide from protein
Sequence: NLVPMVATV
Position: 495-503
Source molecule (GenBank): ADV04400.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Influenza NP ILR
Chemical type: Peptide from protein
Sequence: ILRGSVAHK
Position: 265-273
Source molecule (GenBank): P03466.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Influenza NP ILR
Chemical type: Peptide from protein
Sequence: ILRGSVAHK
Position: 265-273
Source molecule (GenBank): P03466.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CMV pp65 TPR
Chemical type: Peptide from protein
Sequence: TPRVTGGGAM
Position: 417-426
Source molecule (GenBank): ADV04400.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CMV pp65 TPR
Chemical type: Peptide from protein
Sequence: TPRVTGGGAM
Position: 417-426
Source molecule (GenBank): ADV04400.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Influenza M1 GIL
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Influenza M1 GIL
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: EBV LMP2 FLY
Chemical type: Peptide from protein
Sequence: FLYALALLL
Position: 355-363
Source molecule (GenBank): P0C729.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: EBV LMP2 FLY
Chemical type: Peptide from protein
Sequence: FLYALALLL
Position: 355-363
Source molecule (GenBank): P0C729.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: EBV BMF1 GLC
Chemical type: Peptide from protein
Sequence: GLCTLVAML
Position: 259-267
Source molecule (GenBank): YP_401660.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: EBV BMF1 GLC
Chemical type: Peptide from protein
Sequence: GLCTLVAML
Position: 259-267
Source molecule (GenBank): YP_401660.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: EBV BZLF1 RAK
Chemical type: Peptide from protein
Sequence: RAKFKQLL
Position: 190-197
Source molecule (GenBank): P03206.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gp100/Pmel17 YLE
Chemical type: Peptide from protein
Sequence: YLEPGPVTA
Position: 280-288
Source molecule (GenBank): P40967.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gp100/Pmel17 YLE
Chemical type: Peptide from protein
Sequence: YLEPGPVTA
Position: 280-288
Source molecule (GenBank): P40967.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gp100/Pmel17 KTW
Chemical type: Peptide from protein
Sequence: KTWGQYWQV
Position: 154-162
Source molecule (GenBank): P40967.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gp100/Pmel17 KTW
Chemical type: Peptide from protein
Sequence: KTWGQYWQV
Position: 154-162
Source molecule (GenBank): P40967.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Melan-A/MART-1 EAA
Chemical type: Peptide from protein
Sequence: EAAGIGILTV
Position: 26-35
Source molecule (GenBank): U06654
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Melan-A/MART-1 EAA
Chemical type: Peptide from protein
Sequence: EAAGIGILTV
Position: 26-35
Source molecule (GenBank): U06654
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STEAP1 MIA
Chemical type: Peptide from protein
Sequence: MIAVFLPIV
Position: 292-300
Source molecule (GenBank): Q9UHE8.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: STEAP1 MIA
Chemical type: Peptide from protein
Sequence: MIAVFLPIV
Position: 292-300
Source molecule (GenBank): Q9UHE8.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Meloe-1 TLN
Chemical type: Peptide from protein
Sequence: TLNDECWPA
Position: 1-9
Source molecule (GenBank): AJO46348.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Meloe-1 TLN
Chemical type: Peptide from protein
Sequence: TLNDECWPA
Position: 1-9
Source molecule (GenBank): AJO46348.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gp100/Pmel17 IMD
Chemical type: Peptide, no natural source
Sequence: IMDQVPFSV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gp100/Pmel17 IMD
Chemical type: Peptide, no natural source
Sequence: IMDQVPFSV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MAGE-A2 YLQ
Chemical type: Peptide from protein
Sequence: YLQLVFGIEV
Position: 157-166
Source molecule (GenBank): P43356.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MAGE-A2 YLQ
Chemical type: Peptide from protein
Sequence: YLQLVFGIEV
Position: 157-166
Source molecule (GenBank): P43356.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MAGE-A2 LVH
Chemical type: Peptide from protein
Sequence: LVHFLLLKY
Position: 116-124
Source molecule (GenBank): P43356.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Short Term Restimulated

Epitope: CDKN1A GLG
Chemical type: Peptide from protein
Sequence: GLGLPKLYL
Position: 70-78
Source molecule (GenBank): P38936.3
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MAGE-C2 KVL
Chemical type: Peptide from protein
Sequence: KVLEFLAKL
Position: 313-321
Source molecule (GenBank): Q9UBF1.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MAGE-A10 SLL
Chemical type: Peptide from protein
Sequence: SLLKFLAKV
Position: 310-318
Source molecule (GenBank): P43363.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MAGE-C2 LLF
Chemical type: Peptide from protein
Sequence: LLFGLALIEV
Position: 191-200
Source molecule (GenBank): Q9UBF1.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TAG-1 SLG
Chemical type: Peptide from protein
Sequence: SLGWLFLLL
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: STAT1-alpha/ß KLQ
Chemical type: Peptide from protein
Sequence: KLQELNYNL
Position: 350-358
Source molecule (GenBank): P42224.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MC1R TIL
Chemical type: Peptide from protein
Sequence: TILLGIFFL
Position: 244-252
Source molecule (GenBank): Q01726.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Melan-A/MART-1 ILT
Chemical type: Peptide from protein
Sequence: ILTVILGVL
Position: 32-40
Source molecule (GenBank): U06654
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TRP-2 FVW
Chemical type: Peptide from protein
Sequence: FVWLHYYSV
Position: 185-193
Source molecule (GenBank): P40126.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KIF20A AQP
Chemical type: Peptide from protein
Sequence: AQPDTAPLPV
Position: 284-293
Source molecule (GenBank): O95235.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MAGE-A10 GLY
Chemical type: Peptide from protein
Sequence: GLYDGMEHL
Position: 254-262
Source molecule (GenBank): P43363.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p53 RMP
Chemical type: Peptide from protein
Sequence: RMPEAAPPV
Position: 65-73
Source molecule (GenBank): P04637.4
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SSX-2 KAS
Chemical type: Peptide from protein
Sequence: KASEKIFYV
Position: 41-49
Source molecule (GenBank): Q16385.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: STEAP1 FLY
Chemical type: Peptide from protein
Sequence: FLYTLLREV
Position: 86-94
Source molecule (GenBank): Q9UHE8.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TRP-2 SVY
Chemical type: Peptide from protein
Sequence: SVYDFFVWL
Position: 180-188
Source molecule (GenBank): P40126.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GnTV VLP
Chemical type: Peptide from protein
Sequence: VLPDVFIRCV
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Livin SLG
Chemical type: Peptide from protein
Sequence: SLGSPVLGL
Position: 34-42
Source molecule (GenBank): Q96CA5.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MAGE-A1 YLE
Chemical type: Peptide, no natural source
Sequence: YLEYRQVPV
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NY-ESO-1/LAGE-2 SLL
Chemical type: Peptide from protein
Sequence: SLLMWITQC
Position: 157-165
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TRAG-3 ILL
Chemical type: Peptide from protein
Sequence: ILLRDAGLV
Position: 58-66
Source molecule (GenBank): Q9Y5P2.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Melan-A/MART-1 (WT) ELA
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Short Term Restimulated

Epitope: RhoC RLG
Chemical type: Peptide, no natural source
Sequence: RLGLQVRKNK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Short Term Restimulated

Epitope: 1249 A*68:01 WAV
Chemical type: Peptide, no natural source
Sequence: WAVFPSIVGR
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 1249 A*68:01 WAV
Chemical type: Peptide, no natural source
Sequence: WAVFPSIVGR
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 1249 A*68:01 EAS
Chemical type: Peptide, no natural source
Sequence: EASVKVIHR
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 1249 A*68:01 EAS
Chemical type: Peptide, no natural source
Sequence: EASVKVIHR
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 2389 A*01:01 CID
Chemical type: Peptide, no natural source
Sequence: CIDFQPDIY
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 2389 A*01:01 CID
Chemical type: Peptide, no natural source
Sequence: CIDFQPDIY
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 2389 B*40:01 TEL
Chemical type: Peptide, no natural source
Sequence: TELGTAAKL
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 2389 B*40:01 TEL
Chemical type: Peptide, no natural source
Sequence: TELGTAAKL
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 2389 B*40:01 NEA
Chemical type: Peptide, no natural source
Sequence: NEASLSFQAL
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 2389 B*40:01 NEA
Chemical type: Peptide, no natural source
Sequence: NEASLSFQAL
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 7577 A*01:01 AND
Chemical type: Peptide, no natural source
Sequence: ANDNSPFMLY
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 7577 A*01:01 AND
Chemical type: Peptide, no natural source
Sequence: ANDNSPFMLY
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 7577 A*01:09 CMD
Chemical type: Peptide, no natural source
Sequence: CMDFNSNGKY
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 7577 A*01:09 CMD
Chemical type: Peptide, no natural source
Sequence: CMDFNSNGKY
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Telomerase RLF
Chemical type: Peptide from protein
Sequence: RLFFYRKSV
Position: 572-580
Source molecule (GenBank): O14746.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LAGE-1 MLM
Chemical type: Peptide from protein
Sequence: MLMAQEALAFL
Position: 1-11
Source molecule (GenBank): O95987.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated