Reference: Jane C Steele; Sally Roberts; Susan M Rookes; Phillip H Gallimore. "Detection of CD4(+)- and CD8(+)-T-cell responses to human papillomavirus type 1 antigens expressed at various stages of the virus life cycle by using an enzyme-linked immunospot assay of gamma interferon release." Journal of virology (2002).

Epitope: E4 66-80
Chemical type: Peptide from protein
Sequence: EDPEVPEVEDEEKEN
Position: 67-81
Source molecule (GenBank): P06923.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 66-80
Chemical type: Peptide from protein
Sequence: IPKVSPNAFRVFRVR
Position: 66-80
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 66-80
Chemical type: Peptide from protein
Sequence: IPKVSPNAFRVFRVR
Position: 66-80
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E4 71-85
Chemical type: Peptide from protein
Sequence: PEVEDEEKENQRPLG
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E4 76-90
Chemical type: Peptide from protein
Sequence: EEKENQRPLGHPDLS
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E4 36-50
Chemical type: Peptide from protein
Sequence: TTPNSQDRGRPRRSD
Position: 37-51
Source molecule (GenBank): P06923.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E4 41-55
Chemical type: Peptide from protein
Sequence: QDRGRPRRSDKDSRK
Position: 42-56
Source molecule (GenBank): P06923.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E4 1-15
Chemical type: Peptide from protein
Sequence: MADNKAPQGLLGLLQ
Position: 1-15
Source molecule (GenBank): P06923.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E4 6-20
Chemical type: Peptide from protein
Sequence: APQGLLGLLQYTPTT
Position: 7-21
Source molecule (GenBank): P06923.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E4 96-110
Chemical type: Peptide from protein
Sequence: LEVYTQRLKRDILQD
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E6 76-90
Chemical type: Peptide from protein
Sequence: ELRCVTCIKKLSVAE
Position: 96-110
Source molecule (GenBank): NP_040305.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 231-245
Chemical type: Peptide from protein
Sequence: ATCKYPDYIRMNHEA
Position: 231-245
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 236-250
Chemical type: Peptide from protein
Sequence: PDYIRMNHEAYGNSM
Position: 236-250
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E4 56-70
Chemical type: Peptide from protein
Sequence: HLYADGLTDGEDPEV
Position: 57-71
Source molecule (GenBank): P06923.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E4 91-105
Chemical type: Peptide from protein
Sequence: LLRETLEVYTQRLKR
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E6 81-95
Chemical type: Peptide from protein
Sequence: VPEIEEILDRPLLQI
Position: 81-95
Source molecule (GenBank): NP_040305.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E6 86-100
Chemical type: Peptide from protein
Sequence: EILDRPLLQIELRCV
Position: 86-100
Source molecule (GenBank): NP_040305.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E6 91-105
Chemical type: Peptide from protein
Sequence: PLLQIELRCVTCIK
Position: 91-104
Source molecule (GenBank): NP_040305.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E6 126-140
Chemical type: Peptide from protein
Sequence: NRLKAKCSLCRLYAI
Position: 126-140
Source molecule (GenBank): NP_040305.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV2 E6 126-140
Chemical type: Peptide from protein
Sequence: NISGRWTGHCMNCGS
Position: 132-146
Source molecule (GenBank): NP_077116.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV6 E6 126-140
Chemical type: Peptide from protein
Sequence: FIKLNCTWKGRCLHC
Position: 126-140
Source molecule (GenBank): CAS89272.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV16 E6 126-140
Chemical type: Peptide from protein
Sequence: HNIRGRWTGRCMSCC
Position: 126-140
Source molecule (GenBank): ACN22517.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV18 E6 126-140
Chemical type: Peptide from protein
Sequence: RFHNIAGHYRGQCHS
Position: 126-140
Source molecule (GenBank): P06463.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 296-310
Chemical type: Peptide from protein
Sequence: TNYVGTPSGSMVSSD
Position: 296-310
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV2 L1 296-310
Chemical type: Peptide from protein
Sequence: HVYTSTPSGSMVSSE
Position: 300-314
Source molecule (GenBank): ABO14926.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV6 L1 296-310
Chemical type: Peptide from protein
Sequence: SIYVNTPSGSLVSS
Position: 285-298
Source molecule (GenBank): CAS89487.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV16 L1 296-310
Chemical type: Peptide from protein
Sequence: SNYFPTPSGSMVTSD
Position: 315-329
Source molecule (GenBank): ACA14209.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E6 111-125
Chemical type: Peptide from protein
Sequence: KLEVVSNGERVHRVR
Position: 111-125
Source molecule (GenBank): NP_040305.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E6 116-130
Chemical type: Peptide from protein
Sequence: SNGERVHRVRNRLKA
Position: 116-130
Source molecule (GenBank): NP_040305.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV2 E6 111-130
Chemical type: Peptide from protein
Sequence: WEEKEALLVGNKRFHNISGR
Position: 117-136
Source molecule (GenBank): NP_077116.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV6 E6 111-130
Chemical type: Peptide from protein
Sequence: LCEVEKVKHILTKARFIKLN
Position: 111-130
Source molecule (GenBank): CAS89272.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV16 E6 111-130
Chemical type: Peptide from protein
Sequence: CPEEKQRHLDKKQRFHNIRG
Position: 111-130
Source molecule (GenBank): ACN22517.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV18 E6 111-130
Chemical type: Peptide from protein
Sequence: PLNPAEKLRHLNEKRRFHNI
Position: 111-130
Source molecule (GenBank): P06463.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E4 101-115
Chemical type: Peptide from protein
Sequence: QRLKRDILQDLDDFC
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E4 106-120
Chemical type: Peptide from protein
Sequence: DILQDLDDFCRKLGI
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E4 111-125
Chemical type: Peptide from protein
Sequence: LDDFCRKLGIHPWSV
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 76-90
Chemical type: Peptide from protein
Sequence: VFRVRFADPNRFAFG
Position: 76-90
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV2 L1 76-90
Chemical type: Peptide from protein
Sequence: VFHVKLPDPNKFGLP
Position: 87-101
Source molecule (GenBank): ABO14926.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV6 L1 76-90
Chemical type: Peptide from protein
Sequence: VFKVVLPDPNKFALP
Position: 69-83
Source molecule (GenBank): CAS89487.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV16 L1 76-90
Chemical type: Peptide from protein
Sequence: VFRIHLPDPNKFGFP
Position: 98-112
Source molecule (GenBank): ACA14209.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV18 L1 76-90
Chemical type: Peptide from protein
Sequence: VFRVQLPDPNKFGLP
Position: 133-147
Source molecule (GenBank): ABP99807.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 421-435
Chemical type: Peptide from protein
Sequence: EDQYRFLGSSLAAKC
Position: 421-435
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 426-440
Chemical type: Peptide from protein
Sequence: FLGSSLAAKCPEQAP
Position: 426-440
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 431-445
Chemical type: Peptide from protein
Sequence: LAAKCPEQAPPEPQT
Position: 431-445
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 166-180
Chemical type: Peptide from protein
Sequence: CTPASGEHWTSRRCP
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV6 L1 166-180
Chemical type: Peptide from protein
Sequence: CAPPLGEHWGKGTQCT
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV16 L1 166-180
Chemical type: Peptide from protein
Sequence: CKPPIGEHWGKGSPCT
Position: 187-202
Source molecule (GenBank): ACA14209.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV18 L1 166-180
Chemical type: Peptide from protein
Sequence: CAPAIGEHWAKGTACK
Position: 222-237
Source molecule (GenBank): ABP99807.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 71-85
Chemical type: Peptide from protein
Sequence: PNAFRVFRVRFADPN
Position: 71-85
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 106-120
Chemical type: Peptide from protein
Sequence: LRGIEIGRGQPLGIG
Position: 106-120
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 111-125
Chemical type: Peptide from protein
Sequence: IGRGQPLGIGITGHP
Position: 111-125
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 26-40
Chemical type: Peptide from protein
Sequence: RILSTDEYVTRTNLF
Position: 26-40
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 56-70
Chemical type: Peptide from protein
Sequence: FEISSNQTVTIPKVS
Position: 56-70
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 61-75
Chemical type: Peptide from protein
Sequence: NQTVTIPKVSPNAFR
Position: 61-75
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 356-370
Chemical type: Peptide from protein
Sequence: NASTTYSNANFNDFL
Position: 356-370
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV2 L1 351-370
Chemical type: Peptide from protein
Sequence: LCATEASDTNYKATNFKEYL
Position: 355-374
Source molecule (GenBank): ABO14926.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV6 L1 351-370
Chemical type: Peptide from protein
Sequence: LCASVTTSSTYTNSDYKEYM
Position: 340-359
Source molecule (GenBank): CAS89487.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV16 L1 351-370
Chemical type: Peptide from protein
Sequence: LCAAISTSETTYKNTNFKEYL
Position: 370-390
Source molecule (GenBank): ACA14209.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV18 L1 351-370
Chemical type: Peptide from protein
Sequence: ICASTQSPVPGQYDATKFKQYS
Position: 405-426
Source molecule (GenBank): ABP99807.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 481-495
Chemical type: Peptide from protein
Sequence: MTQRTATSSTTKRKT
Position: 481-495
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 41-55
Chemical type: Peptide from protein
Sequence: YHATSERLLLVGHPL
Position: 41-55
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1 51-65
Chemical type: Peptide from protein
Sequence: VGHPLFEISSNQTVT
Position: 51-65
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: QRPLGHPDLSLLRET
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: HPDLSLLRETLEVYT
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: TCIKKLSVAEKLEVV
Position: 101-115
Source molecule (GenBank): NP_040305.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: LSVAEKLEVVSNGER
Position: 106-120
Source molecule (GenBank): NP_040305.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: DIGFGAMDFAALQQD
Position: 206-220
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: AMDFAALQQDKSDVP
Position: 211-225
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: ALQQDKSDVPLDVVQ
Position: 216-230
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: TRGGSVGDKEAVPQS
Position: 266-280
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: VGDKEAVPQSLYLTA
Position: 271-285
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: AVPQSLYLTADAEPR
Position: 276-290
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: MFLVGCTPASGEHWT
Position: 161-175
Source molecule (GenBank): NP_040309.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: GEHWTSRRCPGEQVK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: SRRCPGEQVKLGDCP
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo