Reference: Josephine Baunvig Aagaard; Rosaria Gandini; Anne-Sofie Ravn Ballegaard; Bjarke Krogstrup Jensen; Britta Dorn; Amanda Verner Borg Larsen; Anders Lenstrup; Mathias Sønderholm; Michaela Miehe; Wolfgang Pfützner; Thilo Jakob; Gregers Rom Andersen; Christian Möbs; Edzard Spillner. "Nanobody-based IgG simultaneously inhibit the allergenic and enzymatic activity of the dominant honeybee venom allergen." Nature communications (2026).

Epitope: Epitope of nAb AM1-1 on honeybee Api m 1
Chemical type: Discontinuous protein residues
Discontinuous residues: L40, W41, C42, C64, H67, D68, P71, V73, S75, A76, G77, E78, S79, K80, S88, H89, T90, F100, M119, Y120, L123, T126
Source molecule (GenBank): P00630.3
Assay category: BCell
Result: Positive
Quantitative measurement: 1.76

Epitope: Epitope of nAb AM1-1 on honeybee Api m 1
Chemical type: Discontinuous protein residues
Discontinuous residues: L40, W41, C42, C64, H67, D68, P71, V73, S75, A76, G77, E78, S79, K80, S88, H89, T90, F100, M119, Y120, L123, T126
Source molecule (GenBank): P00630.3
Assay category: BCell
Result: Positive
Quantitative measurement: 1.94

Epitope: Epitope of nAb AM1-1 on honeybee Api m 1
Chemical type: Discontinuous protein residues
Discontinuous residues: L40, W41, C42, C64, H67, D68, P71, V73, S75, A76, G77, E78, S79, K80, S88, H89, T90, F100, M119, Y120, L123, T126
Source molecule (GenBank): P00630.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000155

Epitope: Epitope of nAb AM1-1 on honeybee Api m 1
Chemical type: Discontinuous protein residues
Discontinuous residues: L40, W41, C42, C64, H67, D68, P71, V73, S75, A76, G77, E78, S79, K80, S88, H89, T90, F100, M119, Y120, L123, T126
Source molecule (GenBank): P00630.3
Assay category: BCell
Result: Positive
Quantitative measurement: 80200.0

Epitope: Epitope of nAb AM1-1 on honeybee Api m 1
Chemical type: Discontinuous protein residues
Discontinuous residues: L40, W41, C42, C64, H67, D68, P71, V73, S75, A76, G77, E78, S79, K80, S88, H89, T90, F100, M119, Y120, L123, T126
Source molecule (GenBank): P00630.3
Assay category: BCell
Result: Positive

Epitope: Epitope of nAb AM1-1 on honeybee Api m 1
Chemical type: Discontinuous protein residues
Discontinuous residues: L40, W41, C42, C64, H67, D68, P71, V73, S75, A76, G77, E78, S79, K80, S88, H89, T90, F100, M119, Y120, L123, T126
Source molecule (GenBank): P00630.3
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of nAb AM1-4 on honeybee Api m 1
Chemical type: Discontinuous protein residues
Discontinuous residues: C94, D98, Y101, D102, F121, C128, K130, E132, H133, G139, E140, C146, L147, H148, Y149, T150, V151, D163, L164, R165
Source molecule (GenBank): P00630.3
Assay category: BCell
Result: Positive

Epitope: Epitope of nAb AM1-4 on honeybee Api m 1
Chemical type: Discontinuous protein residues
Discontinuous residues: C94, D98, Y101, D102, F121, C128, K130, E132, H133, G139, E140, C146, L147, H148, Y149, T150, V151, D163, L164, R165
Source molecule (GenBank): P00630.3
Assay category: BCell
Result: Positive
Quantitative measurement: 1.76

Epitope: Epitope of nAb AM1-4 on honeybee Api m 1
Chemical type: Discontinuous protein residues
Discontinuous residues: C94, D98, Y101, D102, F121, C128, K130, E132, H133, G139, E140, C146, L147, H148, Y149, T150, V151, D163, L164, R165
Source molecule (GenBank): P00630.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.16

Epitope: Epitope of nAb AM1-4 on honeybee Api m 1
Chemical type: Discontinuous protein residues
Discontinuous residues: C94, D98, Y101, D102, F121, C128, K130, E132, H133, G139, E140, C146, L147, H148, Y149, T150, V151, D163, L164, R165
Source molecule (GenBank): P00630.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000063

Epitope: Epitope of nAb AM1-4 on honeybee Api m 1
Chemical type: Discontinuous protein residues
Discontinuous residues: C94, D98, Y101, D102, F121, C128, K130, E132, H133, G139, E140, C146, L147, H148, Y149, T150, V151, D163, L164, R165
Source molecule (GenBank): P00630.3
Assay category: BCell
Result: Positive
Quantitative measurement: 394000.0

Epitope: Epitope of nAb AM1-4 on honeybee Api m 1
Chemical type: Discontinuous protein residues
Discontinuous residues: C94, D98, Y101, D102, F121, C128, K130, E132, H133, G139, E140, C146, L147, H148, Y149, T150, V151, D163, L164, R165
Source molecule (GenBank): P00630.3
Assay category: BCell
Result: Positive
Quantitative measurement: 4.1

Epitope: Epitope of nAb AM1-4 on honeybee Api m 1
Chemical type: Discontinuous protein residues
Discontinuous residues: C94, D98, Y101, D102, F121, C128, K130, E132, H133, G139, E140, C146, L147, H148, Y149, T150, V151, D163, L164, R165
Source molecule (GenBank): P00630.3
Assay category: BCell
Result: Positive