Reference: Brian G Pierce; Zhen-Yong Keck; Patrick Lau; Catherine Fauvelle; Ragul Gowthaman; Thomas F Baumert; Thomas R Fuerst; Roy A Mariuzza; Steven K H Foung. "Global mapping of antibody recognition of the hepatitis C virus E2 glycoprotein: Implications for vaccine design." Proceedings of the National Academy of Sciences of the United States of America (2016).

Epitope: CBH-4D epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: C494, V497, V502, G504, V506, Y507, C508, F509, P511, F537, L539, N540, T542, R543, P544, P545, G547, W549, F550, G551, C552, W554, N556, G559, T561, K562, C564, G565, D584, C585, A592, Y594, G598, G600, W602, I603, C607, M608, V609, D610, Y611, R614, H617, Y618, P619, T621, N623, Y624, I626, F627, V629, R630, M631, Y632, V633, H638, L640, A642, A643, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: CBH-4G epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: C494, V497, C503, P505, V506, Y507, C508, F509, P511, G517, F537, L539, N540, T542, R543, P544, P545, G547, W549, F550, G551, C552, W554, N556, G559, T561, C564, G565, D584, A592, T593, Y594, C597, G598, G600, W602, I603, C607, M608, V609, D610, Y611, R614, H617, Y618, P619, T621, N623, Y624, F627, V629, M631, Y632, V633, H638, L640, A642, A643, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: CBH-4B epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: C494, V497, C503, P505, V506, Y507, C508, F509, F537, L539, N540, F550, G551, C552, W554, G559, T561, C564, G565, G600, W602, I603, C607, M608, V609, D610, Y611, R614, H617, Y618, P619, T621, Y624, F627, V629, M631, Y632, V633, H638, L640, A642, A643, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: CBH-20 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: C494, V497, C503, P505, V506, Y507, C508, F509, F537, L539, N540, T542, R543, P544, P545, G547, W549, F550, G551, C552, W554, G559, T561, C564, G565, C569, C581, T583, D584, C585, A592, Y594, C597, G598, G600, W602, I603, C607, M608, Y611, R614, H617, Y618, P619, T621, N623, Y624, F627, M631, Y632, H638, L640, A642, A643, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: CBH-21 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: C494, V497, C503, P505, V506, Y507, C508, F509, F537, L539, N540, T542, R543, P544, P545, G547, W549, F550, G551, C552, W554, G559, T561, C564, G565, C569, C581, T583, D584, C585, A592, T593, Y594, C597, G598, G600, W602, I603, C607, M608, V609, D610, Y611, R614, H617, Y618, P619, T621, N623, Y624, F627, R630, M631, Y632, V633, H638, L640, A642, A643, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: CBH-22 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: C494, V497, C503, P505, V506, Y507, C508, F509, F537, L539, N540, T542, R543, P544, P545, G547, W549, F550, G551, C552, W554, G559, T561, C564, G565, C569, C581, T583, D584, C585, A592, T593, Y594, C597, G598, G600, W602, I603, C607, M608, V609, D610, Y611, R614, H617, Y618, P619, T621, N623, Y624, T625, F627, M631, Y632, V633, H638, L640, A642, A643, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: HC-1 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: C429, C494, C503, G504, P505, V506, C508, F509, W529, G530, D535, F537, L539, C552, W554, G559, C564, C607, Y611, R614, H617, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: HC-1 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: C429, C494, C503, G504, P505, V506, C508, F509, W529, G530, D535, F537, L539, C552, W554, G559, C564, C607, Y611, R614, H617, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: HC-11 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: T425, N428, C429, G436, W437, L438, F442, Y443, C494, V497, V502, C503, G504, V506, Y507, C508, F509, P511, D520, G530, D535, F537, L539, F550, G551, C552, W554, N556, G559, C564, G565, W602, I603, C607, M608, Y611, R614, H617, Y618, P619, C620, T621, Y624, L640, A643, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: HC-11 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: T425, N428, C429, G436, W437, L438, F442, Y443, C494, V497, V502, C503, G504, V506, Y507, C508, F509, P511, D520, G530, D535, F537, L539, F550, G551, C552, W554, N556, G559, C564, G565, W602, I603, C607, M608, Y611, R614, H617, Y618, P619, C620, T621, Y624, L640, A643, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: A27 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S424, T425, A426, L427, N428, C429, W437, L438, C494, V497, A499, V502, C503, G504, V506, Y507, C508, F509, P511, D520, W529, G530, D535, F537, L539, N540, F550, G551, C552, W554, N556, G559, C564, G565, W602, I603, C607, M608, V609, D610, Y611, R614, W616, H617, Y618, P619, T621, N623, Y624, H638, L640, A642, A643, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: A27 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S424, T425, A426, L427, N428, C429, W437, L438, C494, V497, A499, V502, C503, G504, V506, Y507, C508, F509, P511, D520, W529, G530, D535, F537, L539, N540, F550, G551, C552, W554, N556, G559, C564, G565, W602, I603, C607, M608, V609, D610, Y611, R614, W616, H617, Y618, P619, T621, N623, Y624, H638, L640, A642, A643, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: CBH-7 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: C494, V506, C508, F509, P511, F537, L539, W549, C552, W554, C564, Y611, R614, H617, T621, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: CBH-7 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: C494, V506, C508, F509, P511, F537, L539, W549, C552, W554, C564, Y611, R614, H617, T621, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: CBH-23 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: C494, C508, F509, F537, L539, W549, C552, W554, C564, Y611, R614, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: CBH-23 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: C494, C508, F509, F537, L539, W549, C552, W554, C564, Y611, R614, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: HC84.20 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: C429, L441, C494, V497, V502, C503, G504, P505, V506, Y507, C508, F509, P511, T519, D520, F537, L539, C552, W554, G559, C564, C607, M608, Y611, Y613, R614, W616, H617, Y618, P619, T621, L640, A643, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: HC84.20 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: C429, L441, C494, V497, V502, C503, G504, P505, V506, Y507, C508, F509, P511, T519, D520, F537, L539, C552, W554, G559, C564, C607, M608, Y611, Y613, R614, W616, H617, Y618, P619, T621, L640, A643, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: HC84.24 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: C429, F442, Y443, C494, I496, V497, A499, V502, C503, G504, P505, V506, Y507, C508, F509, P511, F537, L539, C552, W554, G559, C564, C607, M608, Y611, R614, H617, Y618, P619, T621, A643, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: HC84.24 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: C429, F442, Y443, C494, I496, V497, A499, V502, C503, G504, P505, V506, Y507, C508, F509, P511, F537, L539, C552, W554, G559, C564, C607, M608, Y611, R614, H617, Y618, P619, T621, A643, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: HC84.26 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: L441, F442, C494, V497, V502, C503, G504, P505, V506, Y507, C508, F509, P511, F537, L539, C552, W554, G559, C564, I603, C607, M608, Y611, R614, H617, Y618, P619, T621, L640, A643, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: HC84.26 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: L441, F442, C494, V497, V502, C503, G504, P505, V506, Y507, C508, F509, P511, F537, L539, C552, W554, G559, C564, I603, C607, M608, Y611, R614, H617, Y618, P619, T621, L640, A643, C644
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: HC33.1 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: L413, G418, W420
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: HC33.1 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: L413, G418, W420
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: HC33.4 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K408, L413, W420
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive

Epitope: HC33.4 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K408, L413, W420
Source molecule (GenBank): AAB66324.1
Assay category: BCell
Result: Positive