Reference: Guo Luo; Selina Yogeshwar; Ling Lin; Emmanuel Jean-Marie Mignot. "T cell reactivity to regulatory factor X4 in type 1 narcolepsy." Scientific reports (2021).

Epitope: RFX4-2
Chemical type: Peptide from protein
Sequence: AFGGSEFFIPEGIQI
Position: 5-19
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-2
Chemical type: Peptide from protein
Sequence: AFGGSEFFIPEGIQI
Position: 5-19
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-2
Chemical type: Peptide from protein
Sequence: AFGGSEFFIPEGIQI
Position: 5-19
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-3
Chemical type: Peptide from protein
Sequence: SEFFIPEGIQIDSRC
Position: 9-23
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-3
Chemical type: Peptide from protein
Sequence: SEFFIPEGIQIDSRC
Position: 9-23
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-3
Chemical type: Peptide from protein
Sequence: SEFFIPEGIQIDSRC
Position: 9-23
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-9
Chemical type: Peptide from protein
Sequence: YHYYGIAVKESSQYY
Position: 33-47
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-22
Chemical type: Peptide from protein
Sequence: PEFPNVKDLNLPASL
Position: 85-99
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-23
Chemical type: Peptide from protein
Sequence: NVKDLNLPASLPEEK
Position: 89-103
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-23
Chemical type: Peptide from protein
Sequence: NVKDLNLPASLPEEK
Position: 89-103
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-23
Chemical type: Peptide from protein
Sequence: NVKDLNLPASLPEEK
Position: 89-103
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-25
Chemical type: Peptide from protein
Sequence: ASLPEEKVSTFIMMY
Position: 97-111
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-25
Chemical type: Peptide from protein
Sequence: ASLPEEKVSTFIMMY
Position: 97-111
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-25
Chemical type: Peptide from protein
Sequence: ASLPEEKVSTFIMMY
Position: 97-111
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-High

Epitope: RFX4-26
Chemical type: Peptide from protein
Sequence: EEKVSTFIMMYRTHC
Position: 101-115
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-29
Chemical type: Peptide from protein
Sequence: THCQRILDTVIRANF
Position: 113-127
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-29
Chemical type: Peptide from protein
Sequence: THCQRILDTVIRANF
Position: 113-127
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-29
Chemical type: Peptide from protein
Sequence: THCQRILDTVIRANF
Position: 113-127
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-41
Chemical type: Peptide from protein
Sequence: CDSILYKAISGVLMP
Position: 161-175
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-42
Chemical type: Peptide from protein
Sequence: LYKAISGVLMPTVLQ
Position: 165-179
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-42
Chemical type: Peptide from protein
Sequence: LYKAISGVLMPTVLQ
Position: 165-179
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-42
Chemical type: Peptide from protein
Sequence: LYKAISGVLMPTVLQ
Position: 165-179
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-43
Chemical type: Peptide from protein
Sequence: ISGVLMPTVLQALPD
Position: 169-183
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-43
Chemical type: Peptide from protein
Sequence: ISGVLMPTVLQALPD
Position: 169-183
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-43
Chemical type: Peptide from protein
Sequence: ISGVLMPTVLQALPD
Position: 169-183
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-60
Chemical type: Peptide from protein
Sequence: QASRTVIHSADITFQ
Position: 237-251
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Positive
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-60
Chemical type: Peptide from protein
Sequence: QASRTVIHSADITFQ
Position: 237-251
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-60
Chemical type: Peptide from protein
Sequence: QASRTVIHSADITFQ
Position: 237-251
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Positive
Host:  8.4
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: RFX4-60
Chemical type: Peptide from protein
Sequence: QASRTVIHSADITFQ
Position: 237-251
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-61
Chemical type: Peptide from protein
Sequence: TVIHSADITFQMLED
Position: 241-255
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Low

Epitope: RFX4-72
Chemical type: Peptide from protein
Sequence: QLYQEFDHLLEEQSP
Position: 285-299
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-72
Chemical type: Peptide from protein
Sequence: QLYQEFDHLLEEQSP
Position: 285-299
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-72
Chemical type: Peptide from protein
Sequence: QLYQEFDHLLEEQSP
Position: 285-299
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-76
Chemical type: Peptide from protein
Sequence: ESYIEWLDTMVDRCV
Position: 301-315
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-76
Chemical type: Peptide from protein
Sequence: ESYIEWLDTMVDRCV
Position: 301-315
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-76
Chemical type: Peptide from protein
Sequence: ESYIEWLDTMVDRCV
Position: 301-315
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-82
Chemical type: Peptide from protein
Sequence: SLKKVAQQFLLMWSC
Position: 325-339
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-86
Chemical type: Peptide from protein
Sequence: GTRVIRDMTLHSAPS
Position: 341-355
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-86
Chemical type: Peptide from protein
Sequence: GTRVIRDMTLHSAPS
Position: 341-355
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Positive
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-86
Chemical type: Peptide from protein
Sequence: GTRVIRDMTLHSAPS
Position: 341-355
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Positive
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-86
Chemical type: Peptide from protein
Sequence: GTRVIRDMTLHSAPS
Position: 341-355
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-86
Chemical type: Peptide from protein
Sequence: GTRVIRDMTLHSAPS
Position: 341-355
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-High

Epitope: RFX4-89
Chemical type: Peptide from protein
Sequence: APSFGSFHLIHLMFD
Position: 353-367
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-89
Chemical type: Peptide from protein
Sequence: APSFGSFHLIHLMFD
Position: 353-367
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-89
Chemical type: Peptide from protein
Sequence: APSFGSFHLIHLMFD
Position: 353-367
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-95
Chemical type: Peptide from protein
Sequence: LHCQERANELMRAMK
Position: 377-391
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Positive
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-95
Chemical type: Peptide from protein
Sequence: LHCQERANELMRAMK
Position: 377-391
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-95
Chemical type: Peptide from protein
Sequence: LHCQERANELMRAMK
Position: 377-391
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-95
Chemical type: Peptide from protein
Sequence: LHCQERANELMRAMK
Position: 377-391
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-96
Chemical type: Peptide from protein
Sequence: ERANELMRAMKGEGS
Position: 381-395
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-96
Chemical type: Peptide from protein
Sequence: ERANELMRAMKGEGS
Position: 381-395
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-96
Chemical type: Peptide from protein
Sequence: ERANELMRAMKGEGS
Position: 381-395
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-100
Chemical type: Peptide from protein
Sequence: AEVREEIILTEAAAP
Position: 397-411
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-100
Chemical type: Peptide from protein
Sequence: AEVREEIILTEAAAP
Position: 397-411
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-100
Chemical type: Peptide from protein
Sequence: AEVREEIILTEAAAP
Position: 397-411
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-101
Chemical type: Peptide from protein
Sequence: EEIILTEAAAPTPSP
Position: 401-415
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-101
Chemical type: Peptide from protein
Sequence: EEIILTEAAAPTPSP
Position: 401-415
Source molecule (GenBank): NP_115880.2
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-101
Chemical type: Peptide from protein
Sequence: EEIILTEAAAPTPSP
Position: 401-415
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-105
Chemical type: Peptide from protein
Sequence: QLYQEFDHLLEEQSP
Position: 285-299
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Low

Epitope: RFX4-112
Chemical type: Peptide from protein
Sequence: TGLSTTGAMQSYTWS
Position: 445-459
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Low

Epitope: RFX4-115
Chemical type: Peptide from protein
Sequence: TWSLTYTVTTAAGSP
Position: 457-471
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-158
Chemical type: Peptide from protein
Sequence: AYINGEASTGWAK
Position: 629-641
Source molecule (GenBank): NP_115880.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-171
Chemical type: Peptide from protein
Sequence: SKPHSTPATLQWLEE
Position: 62-76
Source molecule (GenBank): NP_001193620.1
Assay category: TCell
Result: Negative
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-171
Chemical type: Peptide from protein
Sequence: SKPHSTPATLQWLEE
Position: 62-76
Source molecule (GenBank): NP_001193620.1
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-171
Chemical type: Peptide from protein
Sequence: SKPHSTPATLQWLEE
Position: 62-76
Source molecule (GenBank): NP_001193620.1
Assay category: MhcBinding
Result: Positive-High

Epitope: RFX4-172
Chemical type: Peptide from protein
Sequence: STPATLQWLEENYEI
Position: 66-80
Source molecule (GenBank): NP_001193620.1
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-172
Chemical type: Peptide from protein
Sequence: STPATLQWLEENYEI
Position: 66-80
Source molecule (GenBank): NP_001193620.1
Assay category: TCell
Result: Negative
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-172
Chemical type: Peptide from protein
Sequence: STPATLQWLEENYEI
Position: 66-80
Source molecule (GenBank): NP_001193620.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-173
Chemical type: Peptide from protein
Sequence: TLQWLEENYEIAEGV
Position: 70-84
Source molecule (GenBank): NP_001193620.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: RFX4-175
Chemical type: Peptide from protein
Sequence: YEIAEGVCIPRSALY
Position: 78-92
Source molecule (GenBank): NP_001193620.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-190
Chemical type: Peptide from protein
Sequence: YYGIAVKESSQYYDV
Position: 138-152
Source molecule (GenBank): NP_001193620.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: RFX4-202
Chemical type: Peptide from protein
Sequence: TGLSTTGAMQAYTWS
Position: 548-562
Source molecule (GenBank): BAE48231.1
Assay category: TCell
Result: Negative
Host:  8.4-27.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-202
Chemical type: Peptide from protein
Sequence: TGLSTTGAMQAYTWS
Position: 548-562
Source molecule (GenBank): BAE48231.1
Assay category: TCell
Result: Negative
Host:  20.6-50.1 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RFX4-202
Chemical type: Peptide from protein
Sequence: TGLSTTGAMQAYTWS
Position: 548-562
Source molecule (GenBank): BAE48231.1
Assay category: MhcBinding
Result: Positive-High