Reference: Min Zhao; Kefang Liu; Jiejian Luo; Shuguang Tan; Chuansong Quan; Shuijun Zhang; Yan Chai; Jianxun Qi; Yan Li; Yuhai Bi; Haixia Xiao; Gary Wong; Jianfang Zhou; Taijiao Jiang; Wenjun Liu; Hongjie Yu; Jinghua Yan; Yingxia Liu; Yuelong Shu; Guizhen Wu; Aiping Wu; George F Gao; William J Liu. "Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses." mBio (2018).

Epitope: H1N1-P25
Chemical type: Peptide from protein
Sequence: LYKKLKREITF
Position: 99-109
Source molecule (GenBank): ACP44152.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H1N1-P25
Chemical type: Peptide from protein
Sequence: LYKKLKREITF
Position: 99-109
Source molecule (GenBank): ACP44152.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H1N1-P25
Chemical type: Peptide from protein
Sequence: LYKKLKREITF
Position: 99-109
Source molecule (GenBank): ACP44152.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.794

Epitope: H1N1-P25
Chemical type: Peptide from protein
Sequence: LYKKLKREITF
Position: 99-109
Source molecule (GenBank): ACP44152.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 48.8

Epitope: H7N9-P25
Chemical type: Peptide from protein
Sequence: LYKKLKREMTF
Position: 99-109
Source molecule (GenBank): AHH30774.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H7N9-P25
Chemical type: Peptide from protein
Sequence: LYKKLKREMTF
Position: 99-109
Source molecule (GenBank): AHH30774.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H7N9-P25
Chemical type: Peptide from protein
Sequence: LYKKLKREMTF
Position: 99-109
Source molecule (GenBank): AHH30774.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 3.295

Epitope: H7N9-P25
Chemical type: Peptide from protein
Sequence: LYKKLKREMTF
Position: 99-109
Source molecule (GenBank): AHH30774.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.295

Epitope: H7N9-P25
Chemical type: Peptide from protein
Sequence: LYKKLKREMTF
Position: 99-109
Source molecule (GenBank): AHH30774.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 46.4

Epitope: H1N1-P17
Chemical type: Peptide from protein
Sequence: RAVKLYKKLKREITFHGA
Position: 95-112
Source molecule (GenBank): ACP44152.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H6N1-P17
Chemical type: Peptide from protein
Sequence: RAVKLYKKLKREVTFHGA
Position: 95-112
Source molecule (GenBank): AHI97667.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H7N9-P17
Chemical type: Peptide from protein
Sequence: KAVKLYKKLKREMTFHGA
Position: 95-112
Source molecule (GenBank): AHH30774.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H9N2-P17
Chemical type: Peptide from protein
Sequence: RAVKLYKKLKREMTFHGA
Position: 95-112
Source molecule (GenBank): ABL61489.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H1N1-P18
Chemical type: Peptide from protein
Sequence: KLKREITFHGAKEVSLSY
Position: 102-119
Source molecule (GenBank): ACP44152.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H5N1-P18
Chemical type: Peptide from protein
Sequence: KLKREITFHGAKEVALSY
Position: 102-119
Source molecule (GenBank): AAT70527.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H6N1-P18
Chemical type: Peptide from protein
Sequence: KLKREVTFHGAKEVALSY
Position: 102-119
Source molecule (GenBank): AHI97667.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H7N9-P18
Chemical type: Peptide from protein
Sequence: KLKREMTFHGAKEVALSY
Position: 102-119
Source molecule (GenBank): AHH30774.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H1N1-P22
Chemical type: Peptide from protein
Sequence: MGLIYNRMGTVTTEAAF
Position: 128-144
Source molecule (GenBank): ACP44152.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H5N1-P22
Chemical type: Peptide from protein
Sequence: MGLIYNRMGTVTTEVAF
Position: 128-144
Source molecule (GenBank): AAT70527.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H6N1-P22
Chemical type: Peptide from protein
Sequence: MGLIYNRMGTVTTEVAL
Position: 128-144
Source molecule (GenBank): AHI97667.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H7N2-P22
Chemical type: Peptide from protein
Sequence: MGLIYNRMGTVTAEGAL
Position: 128-144
Source molecule (GenBank): AHH30774.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H1N1-P23
Chemical type: Peptide from protein
Sequence: RMGTVTTEAAFGLVCA
Position: 134-149
Source molecule (GenBank): ACP44152.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H5N1-P23
Chemical type: Peptide from protein
Sequence: RMGTVTTEVAFGLVCA
Position: 134-149
Source molecule (GenBank): AAT70527.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H6N1-P23
Chemical type: Peptide from protein
Sequence: RMGTVTTEVALGLVCA
Position: 134-149
Source molecule (GenBank): AHI97667.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H7N9-P23
Chemical type: Peptide from protein
Sequence: RMGTVTAEGALGLVCA
Position: 134-149
Source molecule (GenBank): AHH30774.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H1N1-P24
Chemical type: Peptide from protein
Sequence: TTEAAFGLVCATCEQIA
Position: 139-155
Source molecule (GenBank): ACP44152.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H6N1-P24
Chemical type: Peptide from protein
Sequence: TTEVALGLVCATCEQIA
Position: 139-155
Source molecule (GenBank): AHI97667.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H7N9-P24
Chemical type: Peptide from protein
Sequence: TAEGALGLVCATCEQIA
Position: 139-155
Source molecule (GenBank): AHH30774.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H1N1-P33
Chemical type: Peptide from protein
Sequence: SEQAAEAMEVANQTRQMV
Position: 196-213
Source molecule (GenBank): ACP44152.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H5N1-P33
Chemical type: Peptide from protein
Sequence: SEQAAEAMEIANQARQMV
Position: 196-213
Source molecule (GenBank): AAT70527.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H6N1-P33
Chemical type: Peptide from protein
Sequence: SEQAAEAMEVASQARQMV
Position: 196-213
Source molecule (GenBank): AHI97667.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H1-NP (366-374)
Chemical type: Peptide from protein
Sequence: ASNENVETM
Position: 366-374
Source molecule (GenBank): ACP41106.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H5/H7-NP (366-374)
Chemical type: Peptide from protein
Sequence: ASNENMEAM
Position: 366-374
Source molecule (GenBank): AAT70629.1
Assay category: TCell
Result: Positive-Low
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H1-PA (224-233)
Chemical type: Peptide from protein
Sequence: PSLENFRAYV
Position: 224-233
Source molecule (GenBank): ACP41104.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H5/H7-PA (224-233)
Chemical type: Peptide from protein
Sequence: SSLENFRAYV
Position: 224-233
Source molecule (GenBank): AAW80714.1
Assay category: TCell
Result: Positive-Low
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo