Reference: Shuguang Tan; Kefang Liu; Yan Chai; Catherine W-H Zhang; Shan Gao; George F Gao; Jianxun Qi. "Distinct PD-L1 binding characteristics of therapeutic monoclonal antibody durvalumab." Protein & cell (2018).

Epitope: Epitope of durvalumab on PD-L1
Chemical type: Discontinuous protein residues
Discontinuous residues: V23, D26, Y56, E58, M59, E60, D61, V111, Y112, R113, M115, A121, D122, Y123, K124, R125, T127
Source molecule (GenBank): Q9NZQ7.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.3

Epitope: Epitope of durvalumab on PD-L1
Chemical type: Discontinuous protein residues
Discontinuous residues: V23, D26, Y56, E58, M59, E60, D61, V111, Y112, R113, M115, A121, D122, Y123, K124, R125, T127
Source molecule (GenBank): Q9NZQ7.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.667

Epitope: Epitope of durvalumab on PD-L1
Chemical type: Discontinuous protein residues
Discontinuous residues: V23, D26, Y56, E58, M59, E60, D61, V111, Y112, R113, M115, A121, D122, Y123, K124, R125, T127
Source molecule (GenBank): Q9NZQ7.1
Assay category: BCell
Result: Positive
Quantitative measurement: 428000.0

Epitope: Epitope of durvalumab on PD-L1
Chemical type: Discontinuous protein residues
Discontinuous residues: V23, D26, Y56, E58, M59, E60, D61, V111, Y112, R113, M115, A121, D122, Y123, K124, R125, T127
Source molecule (GenBank): Q9NZQ7.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000285

Epitope: Epitope of atezolizumab on PD-L1
Chemical type: Discontinuous protein residues
Discontinuous residues: A18, E45, D49, A51, A52, I54, Y56, E58, E60, D61, N63, Q66, V68, H69, V111, R113, M115, S117, Y118, G119, A121, Y123, R125
Source molecule (GenBank): Q9NZQ7.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.75

Epitope: Epitope of atezolizumab on PD-L1
Chemical type: Discontinuous protein residues
Discontinuous residues: A18, E45, D49, A51, A52, I54, Y56, E58, E60, D61, N63, Q66, V68, H69, V111, R113, M115, S117, Y118, G119, A121, Y123, R125
Source molecule (GenBank): Q9NZQ7.1
Assay category: BCell
Result: Positive
Quantitative measurement: 89300.0

Epitope: Epitope of atezolizumab on PD-L1
Chemical type: Discontinuous protein residues
Discontinuous residues: A18, E45, D49, A51, A52, I54, Y56, E58, E60, D61, N63, Q66, V68, H69, V111, R113, M115, S117, Y118, G119, A121, Y123, R125
Source molecule (GenBank): Q9NZQ7.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000156

Epitope: Epitope of avelumab on PD-L1
Chemical type: Discontinuous protein residues
Discontinuous residues: I54, Y56, E58, M59, E60, D61, K62, N63, Q66, H69, D73, K75, V76, H78, R113, M115, S117, A121, Y123, R125
Source molecule (GenBank): Q9NZQ7.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0467

Epitope: Epitope of avelumab on PD-L1
Chemical type: Discontinuous protein residues
Discontinuous residues: I54, Y56, E58, M59, E60, D61, K62, N63, Q66, H69, D73, K75, V76, H78, R113, M115, S117, A121, Y123, R125
Source molecule (GenBank): Q9NZQ7.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1610000.0

Epitope: Epitope of avelumab on PD-L1
Chemical type: Discontinuous protein residues
Discontinuous residues: I54, Y56, E58, M59, E60, D61, K62, N63, Q66, H69, D73, K75, V76, H78, R113, M115, S117, A121, Y123, R125
Source molecule (GenBank): Q9NZQ7.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000753