Reference: Matthew F Cusick; Meiying Yang; Joan C Gill; David D Eckels. "Naturally occurring CD4+ T-cell epitope variants act as altered peptide ligands leading to impaired helper T-cell responses in hepatitis C virus infection." Human immunology (2011).

Epitope: NS3(358-375)
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCHSKKKCD
Position: 358-375
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NS3(358-375)
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCHSKKKCD
Position: 358-375
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3(358-375)
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCHSKKKCD
Position: 358-375
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3(358-375)
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCHSKKKCD
Position: 358-375
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3(358-375)
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCHSKKKCD
Position: 358-375
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3(358-375)
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCHSKKKCD
Position: 358-375
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3(358-375)
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCHSKKKCD
Position: 358-375
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NS3(358-375) variant H369R
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCRSKKKCD
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NS3(358-375) variant H369R
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCRSKKKCD
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3(358-375) variant H369R
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCRSKKKCD
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NS3(358-375) variant S370P
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCHPKKKCD
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NS3(358-375) variant S370P
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCHPKKKCD
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3(358-375) variant S370P
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCHPKKKCD
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3(358-375) variant S370P
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCHPKKKCD
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NS3(358-375) variant K371E
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCHSEKKCD
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3(358-375) variant K371E
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCHSEKKCD
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NS3(358-375) variant K371E
Chemical type: Peptide from protein
Sequence: VIKGGRHLIFCHSEKKCD
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo