Reference: Maria Katsara; Elizabeth Yuriev; Paul A Ramsland; George Deraos; Theodore Tselios; John Matsoukas; Vasso Apostolopoulos. "A double mutation of MBP(83-99) peptide induces IL-4 responses and antagonizes IFN-gamma responses." Journal of neuroimmunology (2008).

Epitope: MBP<sub>83-99</sub>
Chemical type: Peptide from protein
Sequence: ENPVVHFFKNIVTPRTP
Position: 82-98
Source molecule (GenBank): P02687.1
Assay category: BCell
Result: Negative
Host: F 6-8 weeks

Epitope: MBP<sub>83-99</sub>
Chemical type: Peptide from protein
Sequence: ENPVVHFFKNIVTPRTP
Position: 82-98
Source molecule (GenBank): P02687.1
Assay category: BCell
Result: Negative
Host: F 6-8 weeks

Epitope: MBP<sub>83-99</sub>
Chemical type: Peptide from protein
Sequence: ENPVVHFFKNIVTPRTP
Position: 82-98
Source molecule (GenBank): P02687.1
Assay category: TCell
Result: Positive-Low
Host: F 6-8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>83-99</sub>
Chemical type: Peptide from protein
Sequence: ENPVVHFFKNIVTPRTP
Position: 82-98
Source molecule (GenBank): P02687.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>83-99</sub>
Chemical type: Peptide from protein
Sequence: ENPVVHFFKNIVTPRTP
Position: 82-98
Source molecule (GenBank): P02687.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: [A<sup>91</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFANIVTPRTP
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: [A<sup>91</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFANIVTPRTP
Assay category: BCell
Result: Positive-High
Host: F 6-8 weeks

Epitope: [A<sup>91</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFANIVTPRTP
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: [A<sup>91</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFANIVTPRTP
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: [E<sup>91</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFENIVTPRTP
Assay category: BCell
Result: Positive-High
Host: F 6-8 weeks

Epitope: [E<sup>91</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFENIVTPRTP
Assay category: BCell
Result: Negative
Host: F 6-8 weeks

Epitope: [E<sup>91</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFENIVTPRTP
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: [E<sup>91</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFENIVTPRTP
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: [F<sup>91</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFFNIVTPRTP
Assay category: BCell
Result: Positive-High
Host: F 6-8 weeks

Epitope: [F<sup>91</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFFNIVTPRTP
Assay category: BCell
Result: Negative
Host: F 6-8 weeks

Epitope: [F<sup>91</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFFNIVTPRTP
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: [F<sup>91</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFFNIVTPRTP
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: [Y<sup>91</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFYNIVTPRTP
Assay category: BCell
Result: Negative
Host: F 6-8 weeks

Epitope: [Y<sup>91</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFYNIVTPRTP
Assay category: BCell
Result: Negative
Host: F 6-8 weeks

Epitope: [Y<sup>91</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFYNIVTPRTP
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: [Y<sup>91</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFYNIVTPRTP
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: [R<sup>91</sup>A<sup>96</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFRNIVTARTP
Assay category: BCell
Result: Negative
Host: F 6-8 weeks

Epitope: [R<sup>91</sup>A<sup>96</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFRNIVTARTP
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: [R<sup>91</sup>A<sup>96</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFRNIVTARTP
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: [R<sup>91</sup>A<sup>96</sup>]MBP<sub>83-99</sub>
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFRNIVTARTP
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo