Reference: Haihai Jiang; Weiyu Peng; Jianxun Qi; Yan Chai; Hao Song; Yuhai Bi; Pramila Rijal; Haiyuan Wang; Babayemi O Oladejo; Jinhua Liu; Yi Shi; George F Gao; Alain R Townsend; Yan Wu. "Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus." mBio (2020).

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.9
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive
Quantitative measurement: 946.0
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive-Intermediate
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive
Quantitative measurement: 543.0
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 10200.0
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive-Intermediate
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Negative
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive-Low
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N9 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R114, I145, H146, D147, R148, W175, S176, I219, E224, R289, N341, N343, R367, Y401, I424, R427, P428, K429, D431, W434
Source molecule (GenBank): AHZ60015.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive-Intermediate
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive
Quantitative measurement: 946.0
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive-Low
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive
Quantitative measurement: 543.0
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Negative
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 10200.0
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, V149, K150, D151, R152, W179, S180, N222, I223, E228, R293, A343, N344, R368, Y402, Q430, P431, K432
Source molecule (GenBank): AAF77036.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.5
Host: M 6 years

Epitope: Epitope of Z3B2 D102R Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, I149, D151, R152, W179, S180, N222, I223, R225, E228, D248, G249, R293, W296, H297, S339, G342, A343, N344, G345, R368, Y402, R430, P431, E432
Source molecule (GenBank): AHN96347.1
Assay category: BCell
Result: Positive-Low
Host: M 6 years

Epitope: Epitope of Z3B2 D102R Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, I149, D151, R152, W179, S180, N222, I223, R225, E228, D248, G249, R293, W296, H297, S339, G342, A343, N344, G345, R368, Y402, R430, P431, E432
Source molecule (GenBank): AHN96347.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 D102R Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, I149, D151, R152, W179, S180, N222, I223, R225, E228, D248, G249, R293, W296, H297, S339, G342, A343, N344, G345, R368, Y402, R430, P431, E432
Source molecule (GenBank): AHN96347.1
Assay category: BCell
Result: Positive
Quantitative measurement: 401.0
Host: M 6 years

Epitope: Epitope of Z3B2 D102R Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, I149, D151, R152, W179, S180, N222, I223, R225, E228, D248, G249, R293, W296, H297, S339, G342, A343, N344, G345, R368, Y402, R430, P431, E432
Source molecule (GenBank): AHN96347.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 1670.0
Host: M 6 years

Epitope: Epitope of Z3B2 D102R Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, I149, D151, R152, W179, S180, N222, I223, R225, E228, D248, G249, R293, W296, H297, S339, G342, A343, N344, G345, R368, Y402, R430, P431, E432
Source molecule (GenBank): AHN96347.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 D102R Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, I149, D151, R152, W179, S180, N222, I223, R225, E228, D248, G249, R293, W296, H297, S339, G342, A343, N344, G345, R368, Y402, R430, P431, E432
Source molecule (GenBank): AHN96347.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 D102R Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, I149, D151, R152, W179, S180, N222, I223, R225, E228, D248, G249, R293, W296, H297, S339, G342, A343, N344, G345, R368, Y402, R430, P431, E432
Source molecule (GenBank): AHN96347.1
Assay category: BCell
Result: Positive-Intermediate
Host: M 6 years

Epitope: Epitope of Z3B2 D102R Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, I149, D151, R152, W179, S180, N222, I223, R225, E228, D248, G249, R293, W296, H297, S339, G342, A343, N344, G345, R368, Y402, R430, P431, E432
Source molecule (GenBank): AHN96347.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 D102R Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, I149, D151, R152, W179, S180, N222, I223, R225, E228, D248, G249, R293, W296, H297, S339, G342, A343, N344, G345, R368, Y402, R430, P431, E432
Source molecule (GenBank): AHN96347.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 D102R Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, I149, D151, R152, W179, S180, N222, I223, R225, E228, D248, G249, R293, W296, H297, S339, G342, A343, N344, G345, R368, Y402, R430, P431, E432
Source molecule (GenBank): AHN96347.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 D102R Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, I149, D151, R152, W179, S180, N222, I223, R225, E228, D248, G249, R293, W296, H297, S339, G342, A343, N344, G345, R368, Y402, R430, P431, E432
Source molecule (GenBank): AHN96347.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 D102R Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, I149, D151, R152, W179, S180, N222, I223, R225, E228, D248, G249, R293, W296, H297, S339, G342, A343, N344, G345, R368, Y402, R430, P431, E432
Source molecule (GenBank): AHN96347.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 D102R Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, I149, D151, R152, W179, S180, N222, I223, R225, E228, D248, G249, R293, W296, H297, S339, G342, A343, N344, G345, R368, Y402, R430, P431, E432
Source molecule (GenBank): AHN96347.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 D102R Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, I149, D151, R152, W179, S180, N222, I223, R225, E228, D248, G249, R293, W296, H297, S339, G342, A343, N344, G345, R368, Y402, R430, P431, E432
Source molecule (GenBank): AHN96347.1
Assay category: BCell
Result: Positive
Host: M 6 years

Epitope: Epitope of Z3B2 D102R Fab on influenza A N1 neuraminidase
Chemical type: Discontinuous protein residues
Discontinuous residues: R118, I149, D151, R152, W179, S180, N222, I223, R225, E228, D248, G249, R293, W296, H297, S339, G342, A343, N344, G345, R368, Y402, R430, P431, E432
Source molecule (GenBank): AHN96347.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.61
Host: M 6 years