Reference: Takeshi Terashima; Eishiro Mizukoshi; Kuniaki Arai; Tatsuya Yamashita; Mariko Yoshida; Hajime Ota; Ichiro Onishi; Masato Kayahara; Koushiro Ohtsubo; Takashi Kagaya; Masao Honda; Shuichi Kaneko. "P53, hTERT, WT-1, and VEGFR2 are the most suitable targets for cancer vaccine therapy in HLA-A24 positive pancreatic adenocarcinoma." Cancer immunology, immunotherapy : CII (2014).

Epitope: P1 ART 1 188
Chemical type: Peptide from protein
Sequence: EYCLKFTKL
Position: 188-196
Source molecule (GenBank): O94864.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P1 ART 1 188
Chemical type: Peptide from protein
Sequence: EYCLKFTKL
Position: 188-196
Source molecule (GenBank): O94864.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P2 ART 4 161
Chemical type: Peptide from protein
Sequence: AFLRHAAL
Position: 13-20
Source molecule (GenBank): H3BUR4.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P2 ART 4 161
Chemical type: Peptide from protein
Sequence: AFLRHAAL
Position: 13-20
Source molecule (GenBank): H3BUR4.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P3 ART 4 899
Chemical type: Peptide from protein
Sequence: DYPSLSATDI
Position: 75-84
Source molecule (GenBank): Q9ULX3.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P3 ART 4 899
Chemical type: Peptide from protein
Sequence: DYPSLSATDI
Position: 75-84
Source molecule (GenBank): Q9ULX3.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P4 Cyp-B 109
Chemical type: Peptide from protein
Sequence: KFHRVIKDF
Position: 92-100
Source molecule (GenBank): P23284.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P4 Cyp-B 109
Chemical type: Peptide from protein
Sequence: KFHRVIKDF
Position: 92-100
Source molecule (GenBank): P23284.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P5 Cyp-B 315
Chemical type: Peptide from protein
Sequence: DFMIQGGDF
Position: 99-107
Source molecule (GenBank): P23284.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P5 Cyp-B 315
Chemical type: Peptide from protein
Sequence: DFMIQGGDF
Position: 99-107
Source molecule (GenBank): P23284.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P6 Lck 208
Chemical type: Peptide from protein
Sequence: HYTNASDGL
Position: 208-216
Source molecule (GenBank): P06239-3.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P6 Lck 208
Chemical type: Peptide from protein
Sequence: HYTNASDGL
Position: 208-216
Source molecule (GenBank): P06239-3.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P7 Lck 488
Chemical type: Peptide from protein
Sequence: DYLRSVLEDF
Position: 488-497
Source molecule (GenBank): P06239.6
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P7 Lck 488
Chemical type: Peptide from protein
Sequence: DYLRSVLEDF
Position: 488-497
Source molecule (GenBank): P06239.6
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P8 MAGE -A1 135
Chemical type: Peptide from protein
Sequence: NYKHCFPEI
Position: 135-143
Source molecule (GenBank): P43355.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P8 MAGE -A1 135
Chemical type: Peptide from protein
Sequence: NYKHCFPEI
Position: 135-143
Source molecule (GenBank): P43355.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P9 MAGE-A3 195
Chemical type: Peptide from protein
Sequence: IMPKAGLLI
Position: 195-203
Source molecule (GenBank): P43357.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P9 MAGE-A3 195
Chemical type: Peptide from protein
Sequence: IMPKAGLLI
Position: 195-203
Source molecule (GenBank): P43357.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P9 MAGE-A3 195
Chemical type: Peptide from protein
Sequence: IMPKAGLLI
Position: 195-203
Source molecule (GenBank): P43357.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P9 MAGE-A3 195
Chemical type: Peptide from protein
Sequence: IMPKAGLLI
Position: 195-203
Source molecule (GenBank): P43357.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P9 MAGE-A3 195
Chemical type: Peptide from protein
Sequence: IMPKAGLLI
Position: 195-203
Source molecule (GenBank): P43357.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P9 MAGE-A3 195
Chemical type: Peptide from protein
Sequence: IMPKAGLLI
Position: 195-203
Source molecule (GenBank): P43357.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P9 MAGE-A3 195
Chemical type: Peptide from protein
Sequence: IMPKAGLLI
Position: 195-203
Source molecule (GenBank): P43357.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P9 MAGE-A3 195
Chemical type: Peptide from protein
Sequence: IMPKAGLLI
Position: 195-203
Source molecule (GenBank): P43357.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P10 SART1 690
Chemical type: Peptide from protein
Sequence: EYRGFTQDF
Position: 690-698
Source molecule (GenBank): O43290.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P10 SART1 690
Chemical type: Peptide from protein
Sequence: EYRGFTQDF
Position: 690-698
Source molecule (GenBank): O43290.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P11 SART2 899
Chemical type: Peptide from protein
Sequence: SYTRLFLIL
Position: 899-907
Source molecule (GenBank): Q9UL01.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P11 SART2 899
Chemical type: Peptide from protein
Sequence: SYTRLFLIL
Position: 899-907
Source molecule (GenBank): Q9UL01.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P13 Her-2/neu 8
Chemical type: Peptide from protein
Sequence: RWGLLLALL
Position: 8-16
Source molecule (GenBank): J3KRI9.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P13 Her-2/neu 8
Chemical type: Peptide from protein
Sequence: RWGLLLALL
Position: 8-16
Source molecule (GenBank): J3KRI9.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P14 p53 161
Chemical type: Peptide from protein
Sequence: AIYKQSQHM
Position: 161-169
Source molecule (GenBank): E7EQX7.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P14 p53 161
Chemical type: Peptide from protein
Sequence: AIYKQSQHM
Position: 161-169
Source molecule (GenBank): E7EQX7.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P14 p53 161
Chemical type: Peptide from protein
Sequence: AIYKQSQHM
Position: 161-169
Source molecule (GenBank): E7EQX7.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P14 p53 161
Chemical type: Peptide from protein
Sequence: AIYKQSQHM
Position: 161-169
Source molecule (GenBank): E7EQX7.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P15 p53 204
Chemical type: Peptide from protein
Sequence: EYLDDRNTF
Position: 204-212
Source molecule (GenBank): E7EQX7.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P15 p53 204
Chemical type: Peptide from protein
Sequence: EYLDDRNTF
Position: 204-212
Source molecule (GenBank): E7EQX7.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P16 MRP3 765
Chemical type: Peptide from protein
Sequence: VYSDADIFL
Position: 765-773
Source molecule (GenBank): AAD02846.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P16 MRP3 765
Chemical type: Peptide from protein
Sequence: VYSDADIFL
Position: 765-773
Source molecule (GenBank): AAD02846.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P17 MRP3 503
Chemical type: Peptide from protein
Sequence: LYAWEPSFL
Position: 503-511
Source molecule (GenBank): O15438.3
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P17 MRP3 503
Chemical type: Peptide from protein
Sequence: LYAWEPSFL
Position: 503-511
Source molecule (GenBank): O15438.3
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P18 hTERT 461
Chemical type: Peptide from protein
Sequence: VYGFVRACL
Position: 461-469
Source molecule (GenBank): O14746.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P18 hTERT 461
Chemical type: Peptide from protein
Sequence: VYGFVRACL
Position: 461-469
Source molecule (GenBank): O14746.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P18 hTERT 461
Chemical type: Peptide from protein
Sequence: VYGFVRACL
Position: 461-469
Source molecule (GenBank): O14746.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P18 hTERT 461
Chemical type: Peptide from protein
Sequence: VYGFVRACL
Position: 461-469
Source molecule (GenBank): O14746.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P18 hTERT 461
Chemical type: Peptide from protein
Sequence: VYGFVRACL
Position: 461-469
Source molecule (GenBank): O14746.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P18 hTERT 461
Chemical type: Peptide from protein
Sequence: VYGFVRACL
Position: 461-469
Source molecule (GenBank): O14746.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P18 hTERT 461
Chemical type: Peptide from protein
Sequence: VYGFVRACL
Position: 461-469
Source molecule (GenBank): O14746.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P18 hTERT 461
Chemical type: Peptide from protein
Sequence: VYGFVRACL
Position: 461-469
Source molecule (GenBank): O14746.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P19 hTERT 324
Chemical type: Peptide from protein
Sequence: VYAETKHFL
Position: 324-332
Source molecule (GenBank): O14746.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P19 hTERT 324
Chemical type: Peptide from protein
Sequence: VYAETKHFL
Position: 324-332
Source molecule (GenBank): O14746.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P19 hTERT 324
Chemical type: Peptide from protein
Sequence: VYAETKHFL
Position: 324-332
Source molecule (GenBank): O14746.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P19 hTERT 324
Chemical type: Peptide from protein
Sequence: VYAETKHFL
Position: 324-332
Source molecule (GenBank): O14746.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P20 WT-1 235
Chemical type: Peptide from protein
Sequence: CMTWNQMNL
Position: 235-243
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P20 WT-1 235
Chemical type: Peptide from protein
Sequence: CMTWNQMNL
Position: 235-243
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P20 WT-1 235
Chemical type: Peptide from protein
Sequence: CMTWNQMNL
Position: 235-243
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P20 WT-1 235
Chemical type: Peptide from protein
Sequence: CMTWNQMNL
Position: 235-243
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P20 WT-1 235
Chemical type: Peptide from protein
Sequence: CMTWNQMNL
Position: 235-243
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P20 WT-1 235
Chemical type: Peptide from protein
Sequence: CMTWNQMNL
Position: 235-243
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P20 WT-1 235
Chemical type: Peptide from protein
Sequence: CMTWNQMNL
Position: 235-243
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P20 WT-1 235
Chemical type: Peptide from protein
Sequence: CMTWNQMNL
Position: 235-243
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P21 VEGFR2 169
Chemical type: Peptide from protein
Sequence: RFVPDGNRI
Position: 169-177
Source molecule (GenBank): P35968.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P21 VEGFR2 169
Chemical type: Peptide from protein
Sequence: RFVPDGNRI
Position: 169-177
Source molecule (GenBank): P35968.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P21 VEGFR2 169
Chemical type: Peptide from protein
Sequence: RFVPDGNRI
Position: 169-177
Source molecule (GenBank): P35968.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P21 VEGFR2 169
Chemical type: Peptide from protein
Sequence: RFVPDGNRI
Position: 169-177
Source molecule (GenBank): P35968.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P22 VEGFR1 1084
Chemical type: Peptide from protein
Sequence: SYGVLLWEI
Position: 1084-1092
Source molecule (GenBank): P17948.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P22 VEGFR1 1084
Chemical type: Peptide from protein
Sequence: SYGVLLWEI
Position: 1084-1092
Source molecule (GenBank): P17948.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo