Reference: Yik Andy Yeung; Davide Foletti; Xiaodi Deng; Yasmina Abdiche; Pavel Strop; Jacob Glanville; Steven Pitts; Kevin Lindquist; Purnima D Sundar; Marina Sirota; Adela Hasa-Moreno; Amber Pham; Jody Melton Witt; Irene Ni; Jaume Pons; David Shelton; Arvind Rajpal; Javier Chaparro-Riggers. "Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire." Nature communications (2016).

Epitope: Epitope of D2-06-N2 on IsdB NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: M346, M347, T349, F350, N372, D374, Y375, N396, V419, K420, T421, I422, D423, Y424, Y428
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.22

Epitope: Epitope of D2-06-N2 on IsdB NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: M346, M347, T349, F350, N372, D374, Y375, N396, V419, K420, T421, I422, D423, Y424, Y428
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive

Epitope: Epitope of D2-06-N2 on IsdB NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: M346, M347, T349, F350, N372, D374, Y375, N396, V419, K420, T421, I422, D423, Y424, Y428
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive

Epitope: Epitope of D2-06-N2 on IsdB NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: M346, M347, T349, F350, N372, D374, Y375, N396, V419, K420, T421, I422, D423, Y424, Y428
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.016

Epitope: Epitope of D4-30-N2 on NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: M346, T349, F350, N372, Y375, N395, V417, V419, K420, T421, I422, D423, Y424, Y428
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.21

Epitope: Epitope of D4-30-N2 on NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: M346, T349, F350, N372, Y375, N395, V417, V419, K420, T421, I422, D423, Y424, Y428
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.031

Epitope: Epitope of D4-30-N2 on NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: M346, T349, F350, N372, Y375, N395, V417, V419, K420, T421, I422, D423, Y424, Y428
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive

Epitope: Epitope of D4-30-N2 on NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: M346, T349, F350, N372, Y375, N395, V417, V419, K420, T421, I422, D423, Y424, Y428
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive

Epitope: Epitope of D4-10-N1 on NEAT1
Chemical type: Discontinuous protein residues
Discontinuous residues: D159, T161, Q162, F164, Y165, Y167, A168, S169, Q190, S191, F194, T240, H241, F242, N243, E247, Y249
Source molecule (GenBank): Q6GA86.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.17

Epitope: Epitope of D4-10-N1 on NEAT1
Chemical type: Discontinuous protein residues
Discontinuous residues: D159, T161, Q162, F164, Y165, Y167, A168, S169, Q190, S191, F194, T240, H241, F242, N243, E247, Y249
Source molecule (GenBank): Q6GA86.1
Assay category: BCell
Result: Positive

Epitope: Epitope of D4-10-N1 on NEAT1
Chemical type: Discontinuous protein residues
Discontinuous residues: D159, T161, Q162, F164, Y165, Y167, A168, S169, Q190, S191, F194, T240, H241, F242, N243, E247, Y249
Source molecule (GenBank): Q6GA86.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010

Epitope: Epitope of D4-10-N1 on NEAT1
Chemical type: Discontinuous protein residues
Discontinuous residues: D159, T161, Q162, F164, Y165, Y167, A168, S169, Q190, S191, F194, T240, H241, F242, N243, E247, Y249
Source molecule (GenBank): Q6GA86.1
Assay category: BCell
Result: Positive

Epitope: Epitope of D3-13 (P5) on IsdB NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: K325, M326, T327, D328, L329, Q330, D331, K352, P354, K356, V367, I389, S390, T399
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.22

Epitope: Epitope of D3-13 (P5) on IsdB NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: K325, M326, T327, D328, L329, Q330, D331, K352, P354, K356, V367, I389, S390, T399
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.21

Epitope: Epitope of D3-19 (Y10) on NEAT1
Chemical type: Discontinuous protein residues
Discontinuous residues: T121, Y122, P123, N126, Q127, E131, I133, K134, N135, P136, A137, K139, K141, Y214, T216
Source molecule (GenBank): Q6GA86.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.17

Epitope: IsdB NEAT1 epitope residue Y165
Chemical type: Discontinuous protein residues
Discontinuous residues: Y165
Source molecule (GenBank): Q6GA86.1
Assay category: BCell
Result: Positive

Epitope: IsdB linker
Chemical type: Peptide from protein
Sequence: ALDEQVKSAITEFQNVQPTNE
Position: 320-340
Source molecule (GenBank): AHJ06854.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope residues of D1-N2-1 on IsdB NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: D374, V419, T421
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive

Epitope: Epitope residues of D2-N2-2 on IsdB NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: V419, I422
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive

Epitope: Epitope residues of D2-N2-3 on IsdB NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: Y375, V419, T421, I422
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive

Epitope: Epitope residues of D3-N2-4 on IsdB NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: D374, V419, T421, I422
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive

Epitope: Epitope residues of D3-N2-5 on IsdB NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: F350, D374, Y375, V417, V419, T421, I422
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.11

Epitope: Epitope residues of D3-N2-5 on IsdB NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: F350, D374, Y375, V417, V419, T421, I422
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive

Epitope: Epitope residues of D3-N2-5 on IsdB NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: F350, D374, Y375, V417, V419, T421, I422
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive

Epitope: Epitope residues of D3-N2-8 on IsdB NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: D374, Y375, V417, V419, T421, I422
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive

Epitope: Epitope residues of D4-N2-9 on IsdB NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: V419, K420, T421, I422
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive

Epitope: Epitope residues of D4-N2-10 on IsdB NEAT2
Chemical type: Discontinuous protein residues
Discontinuous residues: F350, Y375, V417, V419, T421, I422
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive

Epitope: Epitope residues of D1-N1-1 on IsdB NEAT1
Chemical type: Discontinuous protein residues
Discontinuous residues: F148, Y149, H150, A152, F226
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive

Epitope: Epitope residues of D3-N1-3 on IsdB NEAT1
Chemical type: Discontinuous protein residues
Discontinuous residues: Y149, H150, F226
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive

Epitope: Epitope residues of D3-N1-3 on IsdB NEAT1
Chemical type: Discontinuous protein residues
Discontinuous residues: Y149, H150, F226
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.686

Epitope: Epitope residues of D3-N1-5 on IsdB NEAT1
Chemical type: Discontinuous protein residues
Discontinuous residues: Y149, H150, A152
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive

Epitope: Epitope residues of D3-N1-6 on IsdB NEAT1
Chemical type: Discontinuous protein residues
Discontinuous residues: F148, Y149, H150, A152, Y233
Source molecule (GenBank): Q2YX96.1
Assay category: BCell
Result: Positive