Reference: Wei-Ching Liang; Hongkang Xi; Dawei Sun; Luigi D'Ascenzo; Jonathan Zarzar; Nicole Stephens; Ryan Cook; Yinyin Li; Zhengmao Ye; Marissa Matsumoto; Jian Payandeh; Matthieu Masureel; Yan Wu. "Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability." mAbs (2024).

Epitope: Epitope of Fab h1340.CC on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: W32, N66, Y68, T76, K78, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136, R139
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 378000.0

Epitope: Epitope of Fab h1340.CC on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: W32, N66, Y68, T76, K78, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136, R139
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab h1340.CC on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: W32, N66, Y68, T76, K78, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136, R139
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 1.91

Epitope: Epitope of Fab h1340.CC on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: W32, N66, Y68, T76, K78, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136, R139
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00108

Epitope: Epitope of Fab h1340.CC on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: W32, N66, Y68, T76, K78, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136, R139
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 573000.0

Epitope: Epitope of Fab h1340.CC on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: W32, N66, Y68, T76, K78, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136, R139
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.63

Epitope: Epitope of Fab h1340.CC on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: W32, N66, Y68, T76, K78, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136, R139
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00235

Epitope: Epitope of Fab h1340.CC on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: W32, N66, Y68, T76, K78, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136, R139
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000206

Epitope: Epitope of Fab h1340.CC on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: W32, N66, Y68, T76, K78, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136, R139
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 2.73

Epitope: Epitope of Fab h1340.CC on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: W32, N66, Y68, T76, K78, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136, R139
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.45

Epitope: Epitope of Fab h1340.CC on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: W32, N66, Y68, T76, K78, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136, R139
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 463000.0