Reference: Jason Gorman; Crystal Sao-Fong Cheung; Zhijian Duan; Li Ou; Maple Wang; Xuejun Chen; Cheng Cheng; Andrea Biju; Yaping Sun; Pengfei Wang; Yongping Yang; Baoshan Zhang; Jeffrey C Boyington; Tatsiana Bylund; Sam Charaf; Steven J Chen; Haijuan Du; Amy R Henry; Tracy Liu; Edward K Sarfo; Chaim A Schramm; Chen-Hsiang Shen; Tyler Stephens; I-Ting Teng; John-Paul Todd; Yaroslav Tsybovsky; Raffaello Verardi; Danyi Wang; Shuishu Wang; Zhantong Wang; Cheng-Yan Zheng; Tongqing Zhou; Daniel C Douek; John R Mascola; David D Ho; Mitchell Ho; Peter D Kwong. "Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability." Nature communications (2024).

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000828

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.47

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 185000.0

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 37.7H on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: a: R356, C360, L387, S389, N390, N395, E396, T397, H398, F399, S400, D401, D402, E404, Q405, D408; b: S269, E270, G271, K272, D273, T274, P275, Q324, R325, K327
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 8.11G on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E76, T226, D229; a: R282, W283, I286, E287, A288, E289
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 8.11G on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E76, T226, D229; a: R282, W283, I286, E287, A288, E289
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of Fab 8.11G on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E76, T226, D229; a: R282, W283, I286, E287, A288, E289
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 36800.0

Epitope: Epitope of Fab 8.11G on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E76, T226, D229; a: R282, W283, I286, E287, A288, E289
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 37.1

Epitope: Epitope of Fab 8.11G on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E76, T226, D229; a: R282, W283, I286, E287, A288, E289
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00137

Epitope: Epitope of Fab 8.11G on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E76, T226, D229; a: R282, W283, I286, E287, A288, E289
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 8.11G on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E76, T226, D229; a: R282, W283, I286, E287, A288, E289
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb D5 on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N148, Q149, Y150, E151, S171, H179, G181, T182, R250, D251, Y253, I254; B: L120, S121, H124, M134, S138, H141, L142, Y150; C: L120, I137, H141, L142, I144, F147, N148, Y150, M153, G181, R248
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 26.7

Epitope: Epitope of Nb D5 on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N148, Q149, Y150, E151, S171, H179, G181, T182, R250, D251, Y253, I254; B: L120, S121, H124, M134, S138, H141, L142, Y150; C: L120, I137, H141, L142, I144, F147, N148, Y150, M153, G181, R248
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00323

Epitope: Epitope of Nb D5 on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N148, Q149, Y150, E151, S171, H179, G181, T182, R250, D251, Y253, I254; B: L120, S121, H124, M134, S138, H141, L142, Y150; C: L120, I137, H141, L142, I144, F147, N148, Y150, M153, G181, R248
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 121000.0

Epitope: Epitope of Nb D5 on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N148, Q149, Y150, E151, S171, H179, G181, T182, R250, D251, Y253, I254; B: L120, S121, H124, M134, S138, H141, L142, Y150; C: L120, I137, H141, L142, I144, F147, N148, Y150, M153, G181, R248
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb D5 on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N148, Q149, Y150, E151, S171, H179, G181, T182, R250, D251, Y253, I254; B: L120, S121, H124, M134, S138, H141, L142, Y150; C: L120, I137, H141, L142, I144, F147, N148, Y150, M153, G181, R248
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb D5 on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N148, Q149, Y150, E151, S171, H179, G181, T182, R250, D251, Y253, I254; B: L120, S121, H124, M134, S138, H141, L142, Y150; C: L120, I137, H141, L142, I144, F147, N148, Y150, M153, G181, R248
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb D5 on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N148, Q149, Y150, E151, S171, H179, G181, T182, R250, D251, Y253, I254; B: L120, S121, H124, M134, S138, H141, L142, Y150; C: L120, I137, H141, L142, I144, F147, N148, Y150, M153, G181, R248
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb D5 on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N148, Q149, Y150, E151, S171, H179, G181, T182, R250, D251, Y253, I254; B: L120, S121, H124, M134, S138, H141, L142, Y150; C: L120, I137, H141, L142, I144, F147, N148, Y150, M153, G181, R248
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of Nb D5 on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N148, Q149, Y150, E151, S171, H179, G181, T182, R250, D251, Y253, I254; B: L120, S121, H124, M134, S138, H141, L142, Y150; C: L120, I137, H141, L142, I144, F147, N148, Y150, M153, G181, R248
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb D5 on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N148, Q149, Y150, E151, S171, H179, G181, T182, R250, D251, Y253, I254; B: L120, S121, H124, M134, S138, H141, L142, Y150; C: L120, I137, H141, L142, I144, F147, N148, Y150, M153, G181, R248
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb D5 on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N148, Q149, Y150, E151, S171, H179, G181, T182, R250, D251, Y253, I254; B: L120, S121, H124, M134, S138, H141, L142, Y150; C: L120, I137, H141, L142, I144, F147, N148, Y150, M153, G181, R248
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of Nb D5 on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N148, Q149, Y150, E151, S171, H179, G181, T182, R250, D251, Y253, I254; B: L120, S121, H124, M134, S138, H141, L142, Y150; C: L120, I137, H141, L142, I144, F147, N148, Y150, M153, G181, R248
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb D5 on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N148, Q149, Y150, E151, S171, H179, G181, T182, R250, D251, Y253, I254; B: L120, S121, H124, M134, S138, H141, L142, Y150; C: L120, I137, H141, L142, I144, F147, N148, Y150, M153, G181, R248
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 19.7E on Lassa GPC
Chemical type: Discontinuous protein residues
Discontinuous residues: H92, E104, N109, T110, S111, I112, I113, N114, H115, D156, S169, Y172, S216, Y217, Q218, Q223
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 157.0

Epitope: Epitope of mAb 19.7E on Lassa GPC
Chemical type: Discontinuous protein residues
Discontinuous residues: H92, E104, N109, T110, S111, I112, I113, N114, H115, D156, S169, Y172, S216, Y217, Q218, Q223
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00133

Epitope: Epitope of mAb 19.7E on Lassa GPC
Chemical type: Discontinuous protein residues
Discontinuous residues: H92, E104, N109, T110, S111, I112, I113, N114, H115, D156, S169, Y172, S216, Y217, Q218, Q223
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 8480.0

Epitope: Epitope of mAb 19.7E on Lassa GPC
Chemical type: Discontinuous protein residues
Discontinuous residues: H92, E104, N109, T110, S111, I112, I113, N114, H115, D156, S169, Y172, S216, Y217, Q218, Q223
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of mAb 19.7E on Lassa GPC
Chemical type: Discontinuous protein residues
Discontinuous residues: H92, E104, N109, T110, S111, I112, I113, N114, H115, D156, S169, Y172, S216, Y217, Q218, Q223
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 19.7E on Lassa GPC
Chemical type: Discontinuous protein residues
Discontinuous residues: H92, E104, N109, T110, S111, I112, I113, N114, H115, D156, S169, Y172, S216, Y217, Q218, Q223
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 25.10C on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: C: E76, K88, T226, W227, E228, D229, H230, Q232; c: R282, W283, A288
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 282000.0

Epitope: Epitope of Fab 25.10C on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: C: E76, K88, T226, W227, E228, D229, H230, Q232; c: R282, W283, A288
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00241

Epitope: Epitope of Fab 25.10C on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: C: E76, K88, T226, W227, E228, D229, H230, Q232; c: R282, W283, A288
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 8.56

Epitope: Epitope of Fab 25.10C on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: C: E76, K88, T226, W227, E228, D229, H230, Q232; c: R282, W283, A288
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 36.1F on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N74, E76, K88, M96, T226, W227, E228, D229, H230, C231, Q232, R235, P236; a: I286, E287
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 15.2

Epitope: Epitope of Fab 36.1F on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N74, E76, K88, M96, T226, W227, E228, D229, H230, C231, Q232, R235, P236; a: I286, E287
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00261

Epitope: Epitope of Fab 36.1F on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N74, E76, K88, M96, T226, W227, E228, D229, H230, C231, Q232, R235, P236; a: I286, E287
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 171000.0

Epitope: Epitope of Fab 36.1F on Lassa GPC trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N74, E76, K88, M96, T226, W227, E228, D229, H230, C231, Q232, R235, P236; a: I286, E287
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 18.5C on Lassa GPC
Chemical type: Discontinuous protein residues
Discontinuous residues: R356, I361, P362, L387, S389, S392, L394, N395, T397, H398, F399, S400, D401, D402, E404
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 7.31

Epitope: Epitope of mAb 18.5C on Lassa GPC
Chemical type: Discontinuous protein residues
Discontinuous residues: R356, I361, P362, L387, S389, S392, L394, N395, T397, H398, F399, S400, D401, D402, E404
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000391

Epitope: Epitope of mAb 18.5C on Lassa GPC
Chemical type: Discontinuous protein residues
Discontinuous residues: R356, I361, P362, L387, S389, S392, L394, N395, T397, H398, F399, S400, D401, D402, E404
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive
Quantitative measurement: 53500.0

Epitope: Epitope of mAb 18.5C on Lassa GPC
Chemical type: Discontinuous protein residues
Discontinuous residues: R356, I361, P362, L387, S389, S392, L394, N395, T397, H398, F399, S400, D401, D402, E404
Source molecule (GenBank): P08669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 25.6A on Lassa GPC
Chemical type: Discontinuous protein residues
Discontinuous residues: T265, S267, S269, E270, G271, K272, D273, T274, P275, Q324, R325
Source molecule (GenBank): Q6Y627
Assay category: BCell
Result: Positive
Quantitative measurement: 15.4

Epitope: Epitope of mAb 25.6A on Lassa GPC
Chemical type: Discontinuous protein residues
Discontinuous residues: T265, S267, S269, E270, G271, K272, D273, T274, P275, Q324, R325
Source molecule (GenBank): Q6Y627
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00253

Epitope: Epitope of mAb 25.6A on Lassa GPC
Chemical type: Discontinuous protein residues
Discontinuous residues: T265, S267, S269, E270, G271, K272, D273, T274, P275, Q324, R325
Source molecule (GenBank): Q6Y627
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 25.6A on Lassa GPC
Chemical type: Discontinuous protein residues
Discontinuous residues: T265, S267, S269, E270, G271, K272, D273, T274, P275, Q324, R325
Source molecule (GenBank): Q6Y627
Assay category: BCell
Result: Positive
Quantitative measurement: 164000.0