Reference: Matteo G Levisetti; Danna M Lewis; Anish Suri; Emil R Unanue. "Weak proinsulin peptide-major histocompatibility complexes are targeted in autoimmune diabetes in mice." Diabetes (2008).

Epitope: proinsulin PI-l(47-64)
Chemical type: Peptide from protein
Sequence: SPGDLQTLALEVARQKRG
Position: 71-88
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Positive
Host:  10-16 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: proinsulin PI-l(47-64)
Chemical type: Peptide from protein
Sequence: SPGDLQTLALEVARQKRG
Position: 71-88
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Positive
Host:  10-16 weeks
Culture conditions: In Vivo

Epitope: proinsulin PI-l(47-64)
Chemical type: Peptide from protein
Sequence: SPGDLQTLALEVARQKRG
Position: 71-88
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Positive
Host:  10-16 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: proinsulin PI-l(47-64)
Chemical type: Peptide from protein
Sequence: SPGDLQTLALEVARQKRG
Position: 71-88
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Positive
Host:  10-16 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: proinsulin PI-l(47-64)
Chemical type: Peptide from protein
Sequence: SPGDLQTLALEVARQKRG
Position: 71-88
Source molecule (GenBank): NP_032412.3
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 98900.0

Epitope: proinsulin PI-l(47-64)
Chemical type: Peptide from protein
Sequence: SPGDLQTLALEVARQKRG
Position: 71-88
Source molecule (GenBank): NP_032412.3
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 4800.0

Epitope: MIME
Chemical type: Peptide, no natural source
Sequence: GKKVATTVHAGYG
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: MIME
Chemical type: Peptide, no natural source
Sequence: GKKVATTVHAGYG
Assay category: MhcBinding
Result: Negative

Epitope: proinsulin PI-2(49-66)
Chemical type: Peptide from protein
Sequence: GAGDLQTLALEVAQQKRG
Position: 73-90
Source molecule (GenBank): CAA28433.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 135900.0

Epitope: proinsulin PI-2(49-66)
Chemical type: Peptide from protein
Sequence: GAGDLQTLALEVAQQKRG
Position: 73-90
Source molecule (GenBank): CAA28433.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2100.0

Epitope: proinsulin PI-I(49-6I)
Chemical type: Peptide from protein
Sequence: GDLQTLALEVARQ
Position: 73-85
Source molecule (GenBank): NP_032412.3
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 20000.0

Epitope: proinsulin PI-I(49-6I)
Chemical type: Peptide from protein
Sequence: GDLQTLALEVARQ
Position: 73-85
Source molecule (GenBank): NP_032412.3
Assay category: MhcBinding
Result: Negative

Epitope: INS-B(9-23)
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01326.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 3000.0

Epitope: INS-B(9-23)
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01326.1
Assay category: MhcBinding
Result: Negative