Reference: Tongqing Zhou; Rebecca M Lynch; Lei Chen; Priyamvada Acharya; Xueling Wu; Nicole A Doria-Rose; M Gordon Joyce; Daniel Lingwood; Cinque Soto; Robert T Bailer; Michael J Ernandes; Rui Kong; Nancy S Longo; Mark K Louder; Krisha McKee; Sijy O'Dell; Stephen D Schmidt; Lillian Tran; Zhongjia Yang; Aliaksandr Druz; Timothy S Luongo; Stephanie Moquin; Sanjay Srivatsan; Yongping Yang; Baoshan Zhang; Anqi Zheng; Marie Pancera; Tatsiana Kirys; Ivelin S Georgiev; Tatyana Gindin; Hung-Pin Peng; An-Suei Yang; James C Mullikin; Matthew D Gray; Leonidas Stamatatos; Dennis R Burton; Wayne C Koff; Myron S Cohen; Barton F Haynes; Joseph P Casazza; Mark Connors; Davide Corti; Antonio Lanzavecchia; Quentin J Sattentau; Robin A Weiss; Anthony P West; Pamela J Bjorkman; Johannes F Scheid; Michel C Nussenzweig; Lawrence Shapiro; John R Mascola; Peter D Kwong. "Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors." Cell (2015).

Epitope: Epitope of VRC13 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, E277, A283, K284, T285, S365, G366, G367, D368, L369, I371, T372, Y384, K413, K415, I417, T449, G465, G466, G467, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC13 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, E277, A283, K284, T285, S365, G366, G367, D368, L369, I371, T372, Y384, K413, K415, I417, T449, G465, G466, G467, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC13 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, E277, A283, K284, T285, S365, G366, G367, D368, L369, I371, T372, Y384, K413, K415, I417, T449, G465, G466, G467, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.31

Epitope: Epitope of VRC13 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, E277, A283, K284, T285, S365, G366, G367, D368, L369, I371, T372, Y384, K413, K415, I417, T449, G465, G466, G467, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC13 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, E277, A283, K284, T285, S365, G366, G367, D368, L369, I371, T372, Y384, K413, K415, I417, T449, G465, G466, G467, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC13 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, E277, A283, K284, T285, S365, G366, G367, D368, L369, I371, T372, Y384, K413, K415, I417, T449, G465, G466, G467, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC16 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: T122, N282, A283, K284, T285, S365, G366, G367, D368, E370, I371, N419, M420, W421, Q422, G423, G425, Q426, T449, R450, D451, G452, G453, A454, R463, G466, G467, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.05

Epitope: Epitope of VRC16 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: T122, N282, A283, K284, T285, S365, G366, G367, D368, E370, I371, N419, M420, W421, Q422, G423, G425, Q426, T449, R450, D451, G452, G453, A454, R463, G466, G467, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC16 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: T122, N282, A283, K284, T285, S365, G366, G367, D368, E370, I371, N419, M420, W421, Q422, G423, G425, Q426, T449, R450, D451, G452, G453, A454, R463, G466, G467, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC16 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: T122, N282, A283, K284, T285, S365, G366, G367, D368, E370, I371, N419, M420, W421, Q422, G423, G425, Q426, T449, R450, D451, G452, G453, A454, R463, G466, G467, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC16 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: T122, N282, A283, K284, T285, S365, G366, G367, D368, E370, I371, N419, M420, W421, Q422, G423, G425, Q426, T449, R450, D451, G452, G453, A454, R463, G466, G467, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC16 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: T122, N282, A283, K284, T285, S365, G366, G367, D368, E370, I371, N419, M420, W421, Q422, G423, G425, Q426, T449, R450, D451, G452, G453, A454, R463, G466, G467, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC27 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: L121, T270, N271, N272, A273, K274, S355, G356, G357, D358, E360, I361, M416, W417, A420, G421, Q422, T445, R446, D447, G448, G449, K450, D451, R459, G463, R466
Source molecule (GenBank): O55774
Assay category: BCell
Result: Positive
Quantitative measurement: 3.45

Epitope: Epitope of VRC27 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: L121, T270, N271, N272, A273, K274, S355, G356, G357, D358, E360, I361, M416, W417, A420, G421, Q422, T445, R446, D447, G448, G449, K450, D451, R459, G463, R466
Source molecule (GenBank): O55774
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC27 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: L121, T270, N271, N272, A273, K274, S355, G356, G357, D358, E360, I361, M416, W417, A420, G421, Q422, T445, R446, D447, G448, G449, K450, D451, R459, G463, R466
Source molecule (GenBank): O55774
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC27 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: L121, T270, N271, N272, A273, K274, S355, G356, G357, D358, E360, I361, M416, W417, A420, G421, Q422, T445, R446, D447, G448, G449, K450, D451, R459, G463, R466
Source molecule (GenBank): O55774
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC27 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: L121, T270, N271, N272, A273, K274, S355, G356, G357, D358, E360, I361, M416, W417, A420, G421, Q422, T445, R446, D447, G448, G449, K450, D451, R459, G463, R466
Source molecule (GenBank): O55774
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC27 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: L121, T270, N271, N272, A273, K274, S355, G356, G357, D358, E360, I361, M416, W417, A420, G421, Q422, T445, R446, D447, G448, G449, K450, D451, R459, G463, R466
Source molecule (GenBank): O55774
Assay category: BCell
Result: Positive

Epitope: Epitope of IB2530 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, E277, N278, T280, N281, N282, A283, K284, Q362, S365, G366, D368, I371, W421, T449, R450, D451, G452, G453, A454, N455, R463, G465, G466
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.39

Epitope: Epitope of IB2530 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, E277, N278, T280, N281, N282, A283, K284, Q362, S365, G366, D368, I371, W421, T449, R450, D451, G452, G453, A454, N455, R463, G465, G466
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of IB2530 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, E277, N278, T280, N281, N282, A283, K284, Q362, S365, G366, D368, I371, W421, T449, R450, D451, G452, G453, A454, N455, R463, G465, G466
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of IB2530 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, E277, N278, T280, N281, N282, A283, K284, Q362, S365, G366, D368, I371, W421, T449, R450, D451, G452, G453, A454, N455, R463, G465, G466
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of IB2530 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, E277, N278, T280, N281, N282, A283, K284, Q362, S365, G366, D368, I371, W421, T449, R450, D451, G452, G453, A454, N455, R463, G465, G466
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of IB2530 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, E277, N278, T280, N281, N282, A283, K284, Q362, S365, G366, D368, I371, W421, T449, R450, D451, G452, G453, A454, N455, R463, G465, G466
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 8ANC134 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, N97, E101, E271, T274, N275, N276, A277, K278, G360, D361, I364, N414, M415, W416, R418, V419, G420, Q421, T444, R445, G448, N451, G461, G462, D463, R465
Source molecule (GenBank): AAM66242.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 8ANC134 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, N97, E101, E271, T274, N275, N276, A277, K278, G360, D361, I364, N414, M415, W416, R418, V419, G420, Q421, T444, R445, G448, N451, G461, G462, D463, R465
Source molecule (GenBank): AAM66242.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 8ANC134 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, N97, E101, E271, T274, N275, N276, A277, K278, G360, D361, I364, N414, M415, W416, R418, V419, G420, Q421, T444, R445, G448, N451, G461, G462, D463, R465
Source molecule (GenBank): AAM66242.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 8ANC134 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, N97, E101, E271, T274, N275, N276, A277, K278, G360, D361, I364, N414, M415, W416, R418, V419, G420, Q421, T444, R445, G448, N451, G461, G462, D463, R465
Source molecule (GenBank): AAM66242.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 8ANC134 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, N97, E101, E271, T274, N275, N276, A277, K278, G360, D361, I364, N414, M415, W416, R418, V419, G420, Q421, T444, R445, G448, N451, G461, G462, D463, R465
Source molecule (GenBank): AAM66242.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.45

Epitope: Epitope of 8ANC134 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, N97, E101, E271, T274, N275, N276, A277, K278, G360, D361, I364, N414, M415, W416, R418, V419, G420, Q421, T444, R445, G448, N451, G461, G462, D463, R465
Source molecule (GenBank): AAM66242.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 8ANC131 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, E101, T274, N275, N276, A277, K278, G361, G362, D363, I366, N412, M413, W414, E416, V417, G418, T442, R443, G446, K447, D448, G459, G460, D461, R463
Source molecule (GenBank): P35961.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 8ANC131 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, E101, T274, N275, N276, A277, K278, G361, G362, D363, I366, N412, M413, W414, E416, V417, G418, T442, R443, G446, K447, D448, G459, G460, D461, R463
Source molecule (GenBank): P35961.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 8ANC131 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, E101, T274, N275, N276, A277, K278, G361, G362, D363, I366, N412, M413, W414, E416, V417, G418, T442, R443, G446, K447, D448, G459, G460, D461, R463
Source molecule (GenBank): P35961.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.13

Epitope: Epitope of 8ANC131 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, E101, T274, N275, N276, A277, K278, G361, G362, D363, I366, N412, M413, W414, E416, V417, G418, T442, R443, G446, K447, D448, G459, G460, D461, R463
Source molecule (GenBank): P35961.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 8ANC131 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, E101, T274, N275, N276, A277, K278, G361, G362, D363, I366, N412, M413, W414, E416, V417, G418, T442, R443, G446, K447, D448, G459, G460, D461, R463
Source molecule (GenBank): P35961.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 8ANC131 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, K96, E101, T274, N275, N276, A277, K278, G361, G362, D363, I366, N412, M413, W414, E416, V417, G418, T442, R443, G446, K447, D448, G459, G460, D461, R463
Source molecule (GenBank): P35961.1
Assay category: BCell
Result: Positive

Epitope: Epitope of HJ16 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: T300, N302, A303, K304, T305, Q381, S384, G385, T469, R470, D471, G472, G473, N474, N475, N476, K477, R485, G487, G488
Source molecule (GenBank): Q69994
Assay category: BCell
Result: Positive

Epitope: Epitope of HJ16 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: T300, N302, A303, K304, T305, Q381, S384, G385, T469, R470, D471, G472, G473, N474, N475, N476, K477, R485, G487, G488
Source molecule (GenBank): Q69994
Assay category: BCell
Result: Positive

Epitope: Epitope of HJ16 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: T300, N302, A303, K304, T305, Q381, S384, G385, T469, R470, D471, G472, G473, N474, N475, N476, K477, R485, G487, G488
Source molecule (GenBank): Q69994
Assay category: BCell
Result: Positive
Quantitative measurement: 2.72

Epitope: Epitope of HJ16 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: T300, N302, A303, K304, T305, Q381, S384, G385, T469, R470, D471, G472, G473, N474, N475, N476, K477, R485, G487, G488
Source molecule (GenBank): Q69994
Assay category: BCell
Result: Positive

Epitope: Epitope of HJ16 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: T300, N302, A303, K304, T305, Q381, S384, G385, T469, R470, D471, G472, G473, N474, N475, N476, K477, R485, G487, G488
Source molecule (GenBank): Q69994
Assay category: BCell
Result: Positive

Epitope: Epitope of HJ16 on HIV-1 gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: T300, N302, A303, K304, T305, Q381, S384, G385, T469, R470, D471, G472, G473, N474, N475, N476, K477, R485, G487, G488
Source molecule (GenBank): Q69994
Assay category: BCell
Result: Positive