Reference: Jide Tian; Min Song; Daniel L Kaufman. "Designing Personalized Antigen-Specific Immunotherapies for Autoimmune Diseases-The Case for Using Ignored Target Cell Antigen Determinants." Cells (2022).

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive
Host: F 12-14 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Negative
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive
Host: F 12-13 weeks

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-Low
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Negative
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-Low
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-Low
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Negative
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Negative
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Negative
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Negative
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Negative
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Negative
Host: F 12-13 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: mononuclear cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-Low
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-High
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-Low
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-Low
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI L4-20
Chemical type: Peptide from protein
Sequence: LVHFLPLLALLALWEPK
Position: 4-20
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-High
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: insulin B 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: insulin B 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Positive-Low
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: insulin B 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Negative
Host: F 12-13 weeks

Epitope: insulin B 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Positive
Host: F 12-13 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: insulin B 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Positive-Low
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: insulin B 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Positive
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: insulin B 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Positive
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: insulin B 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Positive-Low
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: insulin B 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_032413.1
Assay category: TCell
Result: Positive
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PPI 82-93
Chemical type: Peptide from protein
Sequence: VARQKRGIVDQC
Position: 82-93
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: mononuclear cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: InsBp8E
Chemical type: Peptide, no natural source
Sequence: HLVERLYLVCGEEG
Assay category: TCell
Result: Positive
Host: F 12-14 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD 524-543
Chemical type: Peptide from protein
Sequence: SRLSKVAPVIKARMMEYGTT
Position: 524-543
Source molecule (GenBank): BAA22893.1
Assay category: TCell
Result: Negative
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD 524-543
Chemical type: Peptide from protein
Sequence: SRLSKVAPVIKARMMEYGTT
Position: 524-543
Source molecule (GenBank): BAA22893.1
Assay category: TCell
Result: Positive
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD 524-543
Chemical type: Peptide from protein
Sequence: SRLSKVAPVIKARMMEYGTT
Position: 524-543
Source molecule (GenBank): BAA22893.1
Assay category: TCell
Result: Positive
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD 524-543
Chemical type: Peptide from protein
Sequence: SRLSKVAPVIKARMMEYGTT
Position: 524-543
Source molecule (GenBank): BAA22893.1
Assay category: TCell
Result: Positive-Low
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HSPp277
Chemical type: Peptide from protein
Sequence: VLGGGCALLRCIPALDSLKPANED
Position: 437-460
Source molecule (GenBank): P63038.1
Assay category: TCell
Result: Positive
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HSPp277
Chemical type: Peptide from protein
Sequence: VLGGGCALLRCIPALDSLKPANED
Position: 437-460
Source molecule (GenBank): P63038.1
Assay category: TCell
Result: Positive
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HSPp277
Chemical type: Peptide from protein
Sequence: VLGGGCALLRCIPALDSLKPANED
Position: 437-460
Source molecule (GenBank): P63038.1
Assay category: TCell
Result: Negative
Host: F 15-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo