Reference: J L Fan; R K Desai; G S Seetharamaiah; J S Dallas; N M Wagle; B S Prabhakar. "Heterogeneity in cellular and antibody responses against thyrotropin receptor in patients with Graves' disease detected using synthetic peptides." Journal of autoimmunity (1993).

Epitope: B92
Chemical type: Peptide from protein
Sequence: LLDLPRDLGGMGCSSPPCE
Position: 12-30
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Negative

Epitope: B92
Chemical type: Peptide from protein
Sequence: LLDLPRDLGGMGCSSPPCE
Position: 12-30
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive
Host:  11-47 years

Epitope: B92
Chemical type: Peptide from protein
Sequence: LLDLPRDLGGMGCSSPPCE
Position: 12-30
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
Host:  11-47 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B92
Chemical type: Peptide from protein
Sequence: LLDLPRDLGGMGCSSPPCE
Position: 12-30
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B91
Chemical type: Peptide from protein
Sequence: HQEEDFRVTCKDIQR
Position: 32-46
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Negative

Epitope: B91
Chemical type: Peptide from protein
Sequence: HQEEDFRVTCKDIQR
Position: 32-46
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive
Host:  11-47 years

Epitope: B91
Chemical type: Peptide from protein
Sequence: HQEEDFRVTCKDIQR
Position: 32-46
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
Host:  11-47 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B91
Chemical type: Peptide from protein
Sequence: HQEEDFRVTCKDIQR
Position: 32-46
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B93
Chemical type: Peptide from protein
Sequence: NALNSPLHQEYEENL
Position: 316-330
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Negative

Epitope: B93
Chemical type: Peptide from protein
Sequence: NALNSPLHQEYEENL
Position: 316-330
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive
Host:  11-47 years

Epitope: B93
Chemical type: Peptide from protein
Sequence: NALNSPLHQEYEENL
Position: 316-330
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
Host:  11-47 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B93
Chemical type: Peptide from protein
Sequence: NALNSPLHQEYEENL
Position: 316-330
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B95
Chemical type: Peptide from protein
Sequence: EYEENLGDSIVGYKEKSKFQD
Position: 325-345
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Negative

Epitope: B95
Chemical type: Peptide from protein
Sequence: EYEENLGDSIVGYKEKSKFQD
Position: 325-345
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive
Host:  11-47 years

Epitope: B95
Chemical type: Peptide from protein
Sequence: EYEENLGDSIVGYKEKSKFQD
Position: 325-345
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
Host:  11-47 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B95
Chemical type: Peptide from protein
Sequence: EYEENLGDSIVGYKEKSKFQD
Position: 325-345
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B94
Chemical type: Peptide from protein
Sequence: GYKEKSKFQDTHNNA
Position: 336-350
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Negative

Epitope: B94
Chemical type: Peptide from protein
Sequence: GYKEKSKFQDTHNNA
Position: 336-350
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive
Host:  11-47 years

Epitope: B94
Chemical type: Peptide from protein
Sequence: GYKEKSKFQDTHNNA
Position: 336-350
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
Host:  11-47 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B94
Chemical type: Peptide from protein
Sequence: GYKEKSKFQDTHNNA
Position: 336-350
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H2
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGF
Position: 352-366
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Negative

Epitope: H2
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGF
Position: 352-366
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive
Host:  11-47 years

Epitope: H2
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGF
Position: 352-366
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
Host:  11-47 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H2
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGF
Position: 352-366
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 3A
Chemical type: Peptide from protein
Sequence: EEQEDEIIGFGQELKN
Position: 357-372
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive
Host:  11-47 years

Epitope: 3A
Chemical type: Peptide from protein
Sequence: EEQEDEIIGFGQELKN
Position: 357-372
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Negative

Epitope: 3A
Chemical type: Peptide from protein
Sequence: EEQEDEIIGFGQELKN
Position: 357-372
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
Host:  11-47 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 3A
Chemical type: Peptide from protein
Sequence: EEQEDEIIGFGQELKN
Position: 357-372
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 1B
Chemical type: Peptide from protein
Sequence: EIIGFGQELKNPQEE
Position: 362-376
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Negative

Epitope: 1B
Chemical type: Peptide from protein
Sequence: EIIGFGQELKNPQEE
Position: 362-376
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive
Host:  11-47 years

Epitope: 1B
Chemical type: Peptide from protein
Sequence: EIIGFGQELKNPQEE
Position: 362-376
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
Host:  11-47 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 1B
Chemical type: Peptide from protein
Sequence: EIIGFGQELKNPQEE
Position: 362-376
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 3B
Chemical type: Peptide from protein
Sequence: PQEETLQAFDSHYDYT
Position: 373-388
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Negative

Epitope: 3B
Chemical type: Peptide from protein
Sequence: PQEETLQAFDSHYDYT
Position: 373-388
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive
Host:  11-47 years

Epitope: 3B
Chemical type: Peptide from protein
Sequence: PQEETLQAFDSHYDYT
Position: 373-388
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
Host:  11-47 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 3B
Chemical type: Peptide from protein
Sequence: PQEETLQAFDSHYDYT
Position: 373-388
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H4
Chemical type: Peptide from protein
Sequence: TLQAFDSHYDYTICGDSKDMV
Assay category: BCell
Result: Negative

Epitope: H4
Chemical type: Peptide from protein
Sequence: TLQAFDSHYDYTICGDSKDMV
Assay category: BCell
Result: Positive
Host:  11-47 years

Epitope: H4
Chemical type: Peptide from protein
Sequence: TLQAFDSHYDYTICGDSKDMV
Assay category: TCell
Result: Positive
Host:  11-47 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H4
Chemical type: Peptide from protein
Sequence: TLQAFDSHYDYTICGDSKDMV
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo