Reference: F Susan Wong; Antonis K Moustakas; Li Wen; George K Papadopoulos; Charles A Janeway. "Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2K(d) that stimulates CD8 T cells in insulin-dependent diabetes mellitus." Proceedings of the National Academy of Sciences of the United States of America (2002).

Epitope: Insulin B15-23
Chemical type: Peptide from protein
Sequence: LYLVCGERG
Position: 36-44
Source molecule (GenBank): 720922A
Assay category: TCell
Result: Positive
Host: F 7 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Cell Line / Clone

Epitope: Insulin B15-23
Chemical type: Peptide from protein
Sequence: LYLVCGERG
Position: 36-44
Source molecule (GenBank): 720922A
Assay category: TCell
Result: Positive
Host: F 7 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Cell Line / Clone

Epitope: Insulin B15-23
Chemical type: Peptide from protein
Sequence: LYLVCGERG
Position: 36-44
Source molecule (GenBank): 720922A
Assay category: TCell
Result: Positive
Host: F 7 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Cell Line / Clone

Epitope: Insulin B15-23
Chemical type: Peptide from protein
Sequence: LYLVCGERG
Position: 36-44
Source molecule (GenBank): 720922A
Assay category: MhcBinding
Result: Positive-Low

Epitope: Insulin B15-23 with G9Y substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGERY
Assay category: MhcBinding
Result: Positive-Low

Epitope: Insulin B15-23 with G9V substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGERV
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with C5A substitution
Chemical type: Peptide, no natural source
Sequence: LYLVAGERG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with C5D substitution
Chemical type: Peptide, no natural source
Sequence: LYLVDGERG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with C5E substitution
Chemical type: Peptide, no natural source
Sequence: LYLVEGERG
Assay category: MhcBinding
Result: Positive-Low

Epitope: Insulin B15-23 with C5F substitution
Chemical type: Peptide, no natural source
Sequence: LYLVFGERG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with C5G substitution
Chemical type: Peptide, no natural source
Sequence: LYLVGGERG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with C5H substitution
Chemical type: Peptide, no natural source
Sequence: LYLVHGERG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with C5K substitution
Chemical type: Peptide, no natural source
Sequence: LYLVKERG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with C5L substitution
Chemical type: Peptide, no natural source
Sequence: LYLVLGERG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with C5M substitution
Chemical type: Peptide, no natural source
Sequence: LYLVMGERG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with C5N substitution
Chemical type: Peptide, no natural source
Sequence: LYLVNGERG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with C5P substitution
Chemical type: Peptide, no natural source
Sequence: LYLVPGERG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with C5Q substitution
Chemical type: Peptide, no natural source
Sequence: LYLVQGERG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with C5S substitution
Chemical type: Peptide, no natural source
Sequence: LYLVSGERG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with C5T substitution
Chemical type: Peptide, no natural source
Sequence: LYLVTGERG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with C5V substitution
Chemical type: Peptide, no natural source
Sequence: LYLVVGERG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with C5W substitution
Chemical type: Peptide, no natural source
Sequence: LYLVWGERG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with C5Y substitution
Chemical type: Peptide, no natural source
Sequence: LYLVYGERG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7A substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGARG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7C substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGCRG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7D substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGDRG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7F substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGFRG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7G substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGGRG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7H substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGHRG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7I substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGIRG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7K substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGKRG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7L substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGLRG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7M substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGMRG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7N substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGNRG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7P substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGPRG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7Q substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGQRG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7R substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGRRG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7S substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGSRG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7T substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGTRG
Assay category: MhcBinding
Result: Positive

Epitope: Insulin B15-23 with E7W substitution
Chemical type: Peptide, no natural source
Sequence: LYLVCGWRG
Assay category: MhcBinding
Result: Positive