Reference: Courtney Voss; Sally Esmail; Xuguang Liu; Michael J Knauer; Suzanne Ackloo; Tomonori Kaneko; Lori Lowes; Peter Stogios; Almagul Seitova; Ashley Hutchinson; Farhad Yusifov; Tatiana Skarina; Elena Evdokimova; Peter Loppnau; Pegah Ghiabi; Taraneh Haijan; Shanshan Zhong; Husam Abdoh; Benjamin D Hedley; Vipin Bhayana; Claudio M Martin; Marat Slessarev; Benjamin Chin-Yee; Douglas D Fraser; Ian Chin-Yee; Shawn Sc Li. "Epitope-specific antibody responses differentiate COVID-19 outcomes and variants of concern." JCI insight (2021).

Epitope: S-21
Chemical type: Peptide from protein
Sequence: RTQLPPAYTNSFTRG
Position: 21-35
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: S-31
Chemical type: Peptide from protein
Sequence: SFTRGVYYPDKVFRS
Position: 31-45
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: S-36
Chemical type: Peptide from protein
Sequence: VYYPDKVFRSSVLHS
Position: 36-50
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: S-176
Chemical type: Peptide from protein
Sequence: LMDLEGKQGNFKNLR
Position: 176-190
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: S-451
Chemical type: Peptide from protein
Sequence: YLYRLFRKSNLKPFE
Position: 451-465
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S-545
Chemical type: Peptide from protein
Sequence: GLTGTGVLTESNKKFLPFQQF
Position: 545-565
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S-551
Chemical type: Peptide from protein
Sequence: VLTESNKKFLPFQQF
Position: 551-565
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S-551
Chemical type: Peptide from protein
Sequence: VLTESNKKFLPFQQF
Position: 551-565
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative

Epitope: S-551
Chemical type: Peptide from protein
Sequence: VLTESNKKFLPFQQF
Position: 551-565
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S-556
Chemical type: Peptide from protein
Sequence: NKKFLPFQQFGRDIA
Position: 556-570
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S-566
Chemical type: Peptide from protein
Sequence: GRDIADTTDAVRDPQTLEILDI
Position: 566-587
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S-571
Chemical type: Peptide from protein
Sequence: DTTDAVRDPQTLEIL
Position: 571-585
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S-576
Chemical type: Peptide from protein
Sequence: VRDPQTLEILDITPC
Position: 576-590
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S-621
Chemical type: Peptide from protein
Sequence: PVAIHADQLTPTWRV
Position: 621-635
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S-646
Chemical type: Peptide from protein
Sequence: IHADQLTPTWRVYSTGS
Position: 624-640
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S-626
Chemical type: Peptide from protein
Sequence: ADQLTPTWRVYSTGS
Position: 626-640
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S-661
Chemical type: Peptide from protein
Sequence: ECDIPIGAGICASYQ
Position: 661-675
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: S-671
Chemical type: Peptide from protein
Sequence: CASYQTQTNSPRRAR
Position: 671-685
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: S-676
Chemical type: Peptide from protein
Sequence: TQTNSPRRARSVASQ
Position: 676-690
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: S-691
Chemical type: Peptide from protein
Sequence: SIIAYTMSLGAENSV
Position: 691-705
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: S-696
Chemical type: Peptide from protein
Sequence: TMSLGAENSVAYSNN
Position: 696-710
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: S-796
Chemical type: Peptide from protein
Sequence: DFGGFNFSQILPDPS
Position: 796-810
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: S-811
Chemical type: Peptide from protein
Sequence: KPSKRSFIEDLLFNK
Position: 811-825
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: S-811
Chemical type: Peptide from protein
Sequence: KPSKRSFIEDLLFNK
Position: 811-825
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S-811
Chemical type: Peptide from protein
Sequence: KPSKRSFIEDLLFNK
Position: 811-825
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative

Epitope: S-816
Chemical type: Peptide from protein
Sequence: SFIEDLLFNKVTLAD
Position: 816-830
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: S-881
Chemical type: Peptide from protein
Sequence: TITSGWTFGAGAALQ
Position: 881-895
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: S-881
Chemical type: Peptide from protein
Sequence: TITSGWTFGAGAALQ
Position: 881-895
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S-881
Chemical type: Peptide from protein
Sequence: TITSGWTFGAGAALQ
Position: 881-895
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative

Epitope: S-1146
Chemical type: Peptide from protein
Sequence: DSFKEELDKYFKNHT
Position: 1146-1160
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: S-1146
Chemical type: Peptide from protein
Sequence: DSFKEELDKYFKNHT
Position: 1146-1160
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative

Epitope: S-1166
Chemical type: Peptide from protein
Sequence: LGDISGINASVVNIQ
Position: 1166-1180
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S-1216
Chemical type: Peptide from protein
Sequence: IWLGFIAGLIAIVMV
Position: 1216-1230
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: N-1
Chemical type: Peptide from protein
Sequence: MSDNGPQNQRNAPRI
Position: 1-15
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-Low

Epitope: N-6
Chemical type: Peptide from protein
Sequence: PQNQRNAPRITFGGP
Position: 6-20
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-Low

Epitope: N-31
Chemical type: Peptide from protein
Sequence: ERSGARSKQRRPQGL
Position: 31-45
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-Low

Epitope: N-36
Chemical type: Peptide from protein
Sequence: RSKQRRPQGLPNNTA
Position: 36-50
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-Low

Epitope: N-41
Chemical type: Peptide from protein
Sequence: RPQGLPNNTASWFTA
Position: 41-55
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-Low

Epitope: N-146
Chemical type: Peptide from protein
Sequence: IGTRNPANNAAIVLQ
Position: 146-160
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-High

Epitope: N-153
Chemical type: Peptide from protein
Sequence: NNNAATVLQLPQGTTLPKG
Assay category: BCell
Result: Positive-High

Epitope: N-156
Chemical type: Peptide from protein
Sequence: AIVLQLPQGTTLPKG
Position: 156-170
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-High

Epitope: N-156
Chemical type: Peptide from protein
Sequence: AIVLQLPQGTTLPKG
Position: 156-170
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-Low

Epitope: N-156
Chemical type: Peptide from protein
Sequence: AIVLQLPQGTTLPKG
Position: 156-170
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Negative

Epitope: N-161
Chemical type: Peptide from protein
Sequence: LPQGTTLPKGFYAEG
Position: 161-175
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-High

Epitope: N-191
Chemical type: Peptide from protein
Sequence: RNSSRNSTPGSSRGT
Position: 191-205
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-Low

Epitope: N-196
Chemical type: Peptide from protein
Sequence: NSTPGSSRGTSPARM
Position: 196-210
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-Low

Epitope: N-201
Chemical type: Peptide from protein
Sequence: SSRGTSPARMAGNGG
Position: 201-215
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-Low

Epitope: N-221
Chemical type: Peptide from protein
Sequence: LLLLDRLNQLESKMS
Position: 221-235
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive

Epitope: N-231
Chemical type: Peptide from protein
Sequence: ESKMSGKGQQQQGQT
Position: 231-245
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive

Epitope: N-236
Chemical type: Peptide from protein
Sequence: GKGQQQQGQTVTKKS
Position: 236-250
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive

Epitope: N-241
Chemical type: Peptide from protein
Sequence: QQGQTVTKKSAAEAS
Position: 241-255
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive

Epitope: N-246
Chemical type: Peptide from protein
Sequence: VTKKSAAEASKKPRQ
Position: 246-260
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive

Epitope: N-251
Chemical type: Peptide from protein
Sequence: AAEASKKPRQKRTAT
Position: 251-265
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive

Epitope: N-355
Chemical type: Peptide from protein
Sequence: KHIDAYKTFPPTEPKKDKKKK
Position: 355-375
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-High

Epitope: N-361
Chemical type: Peptide from protein
Sequence: KTFPPTEPKKDKKKK
Position: 361-375
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-High

Epitope: N-361
Chemical type: Peptide from protein
Sequence: KTFPPTEPKKDKKKK
Position: 361-375
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Negative

Epitope: N-361
Chemical type: Peptide from protein
Sequence: KTFPPTEPKKDKKKK
Position: 361-375
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-Low

Epitope: N-366
Chemical type: Peptide from protein
Sequence: TEPKKDKKKKADETQ
Position: 366-380
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-High

Epitope: N-368
Chemical type: Peptide from protein
Sequence: PKKDKKKKTDEAQPLPQRQKKQP
Assay category: BCell
Result: Positive-High

Epitope: N-371
Chemical type: Peptide from protein
Sequence: DKKKKADETQALPQR
Position: 371-385
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-High

Epitope: N-381
Chemical type: Peptide from protein
Sequence: ALPQRQKKQQTVTLL
Position: 381-395
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-High

Epitope: N-381
Chemical type: Peptide from protein
Sequence: QPLPQRQKKQPTVTLLPAADM
Assay category: BCell
Result: Positive-High

Epitope: N-386
Chemical type: Peptide from protein
Sequence: QKKQQTVTLLPAADL
Position: 386-400
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive-High

Epitope: S-HV 69-70 deletion ( B.1.1.7 )
Chemical type: Peptide from protein
Sequence: TWFHAISGTNGTK
Position: 63-75
Source molecule (GenBank): QSJ05725.1
Assay category: BCell
Result: Positive

Epitope: S-Y144 deletion ( B.1.1.7 )
Chemical type: Peptide from protein
Sequence: NDPFLGVYHKNNKS
Position: 135-148
Source molecule (GenBank): QSJ05725.1
Assay category: BCell
Result: Positive

Epitope: S-A570D ( B.1.1.7 )
Chemical type: Peptide from protein
Sequence: QQFGRDIDDTTDAVR
Position: 560-574
Source molecule (GenBank): QSJ05725.1
Assay category: BCell
Result: Negative

Epitope: S-P681H ( B.1.1.7 )
Chemical type: Peptide from protein
Sequence: CASYQTQTNSHRRAR
Position: 668-682
Source molecule (GenBank): QSJ05725.1
Assay category: BCell
Result: Positive-Low

Epitope: S-P681H (centred) ( B.1.1.7 )
Chemical type: Peptide from protein
Sequence: YQTQTNSHRRARSVA
Position: 671-685
Source molecule (GenBank): QSJ05725.1
Assay category: BCell
Result: Positive-Low

Epitope: S-T716I ( B.1.1.7 )
Chemical type: Peptide from protein
Sequence: NNSIAIPINFTISVT
Position: 706-720
Source molecule (GenBank): QSJ05725.1
Assay category: BCell
Result: Positive

Epitope: S-S982A ( B.1.1.7 )
Chemical type: Peptide from protein
Sequence: SVLNDILARLDKVEA
Position: 972-986
Source molecule (GenBank): QSJ05725.1
Assay category: BCell
Result: Positive

Epitope: S-D1118H ( B.1.1.7 )
Chemical type: Peptide from protein
Sequence: EPQIITTHNTFVSGN
Position: 1108-1122
Source molecule (GenBank): QSJ05725.1
Assay category: BCell
Result: Positive

Epitope: S-N501Y ( B.1.1.7   501.V2)
Chemical type: Peptide from protein
Sequence: SYGFQPTYGVGYQPY
Position: 491-505
Source molecule (GenBank): QSJ05725.1
Assay category: BCell
Result: Positive

Epitope: S-E484K ( 501.V2)
Chemical type: Peptide from protein
Sequence: STPCNGVKGFNCYFP
Position: 479-493
Source molecule (GenBank): QVV18961.1
Assay category: BCell
Result: Negative

Epitope: S-K417N ( 501.V2)
Chemical type: Peptide from protein
Sequence: IAPGQTGNIADYNYK
Position: 410-424
Source molecule (GenBank): QTA94406.1
Assay category: BCell
Result: Positive

Epitope: S-D614G (+)
Chemical type: Peptide from protein
Sequence: QVAVLYQGVNCTEVP
Position: 616-630
Source molecule (GenBank): CAD0240757.1
Assay category: BCell
Result: Positive

Epitope: S-A831V (+)
Chemical type: Peptide from protein
Sequence: NKVTLADVGFIKQYG
Position: 824-838
Source molecule (GenBank): QQP64673.1
Assay category: BCell
Result: Positive

Epitope: S-N439K (+)
Chemical type: Peptide from protein
Sequence: CVIAWNSKNLDSKVG
Position: 432-446
Source molecule (GenBank): QRO03339.1
Assay category: BCell
Result: Positive

Epitope: S-V483A (+)
Chemical type: Peptide from protein
Sequence: GSTPCNGAEGFNCYF
Position: 476-490
Source molecule (GenBank): QSF09476.1
Assay category: BCell
Result: Negative

Epitope: S-L452R (+)
Chemical type: Peptide from protein
Sequence: VGGNYNYRYRLFRKS
Position: 452-466
Source molecule (GenBank): QUH56559.1
Assay category: BCell
Result: Negative

Epitope: S-A475V (+)
Chemical type: Peptide from protein
Sequence: ISTEIYQVGSTPCNG
Position: 468-482
Source molecule (GenBank): QWU20031.1
Assay category: BCell
Result: Negative

Epitope: S-F490L (+)
Chemical type: Peptide from protein
Sequence: VEGFNCYLPLQSYGF
Position: 483-497
Source molecule (GenBank): QUL62581.1
Assay category: BCell
Result: Positive

Epitope: S-V367F (+)
Chemical type: Peptide from protein
Sequence: NCVADYSFLYNSASF
Position: 360-374
Source molecule (GenBank): QWO74701.1
Assay category: BCell
Result: Positive

Epitope: S-Q414E (+)
Chemical type: Peptide from protein
Sequence: VRQIAPGETGKIADY
Assay category: BCell
Result: Positive

Epitope: S-Y508H (+)
Chemical type: Peptide from protein
Sequence: NGVGYQPHRVVVLSF
Position: 501-515
Source molecule (GenBank): QQW60654.1
Assay category: BCell
Result: Positive

Epitope: S-I468F (+)
Chemical type: Peptide from protein
Sequence: LKPFERDFSTEIYQA
Position: 461-475
Source molecule (GenBank): QOC77967.1
Assay category: BCell
Result: Negative

Epitope: S-N165Q (+)
Chemical type: Peptide from protein
Sequence: RVYSSANQCTFEYVS
Assay category: BCell
Result: Positive

Epitope: N-D3L ( B.1.1.7 )
Chemical type: Peptide from protein
Sequence: MSLNGPQNQRNAPRI
Position: 1-15
Source molecule (GenBank): QUF24372.1
Assay category: BCell
Result: Positive-Low

Epitope: N-S235F ( B.1.1.7 )
Chemical type: Peptide from protein
Sequence: NQLESKMFGKGQQQQ
Position: 228-242
Source molecule (GenBank): QTY61797.1
Assay category: BCell
Result: Positive-Low

Epitope: S-181
Chemical type: Peptide from protein
Sequence: GKQGNFKNLREFVFK
Position: 181-195
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative

Epitope: S-351
Chemical type: Peptide from protein
Sequence: YAWNRKRISNCVADY
Position: 351-365
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative

Epitope: S-801
Chemical type: Peptide from protein
Sequence: NFSQILPDPSKPSKR
Position: 801-815
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative

Epitope: S-1041
Chemical type: Peptide from protein
Sequence: DFCGKGYHLMSFPQS
Position: 1041-1055
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative

Epitope: S-1091
Chemical type: Peptide from protein
Sequence: REGVFVSNGTHWFVT
Position: 1091-1105
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative

Epitope: S-491
Chemical type: Peptide from protein
Sequence: PLQSYGFQPTNGVGT
Assay category: BCell
Result: Negative

Epitope: S-802
Chemical type: Peptide from protein
Sequence: FSQILPDPSKPSKRSFIE
Position: 802-819
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: S-888
Chemical type: Peptide from protein
Sequence: FGAGAALQIPFAMQM
Position: 888-902
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative

Epitope: S-895
Chemical type: Peptide from protein
Sequence: QIPFAMQMAYRFNGI
Position: 895-909
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative

Epitope: S-287
Chemical type: Peptide from protein
Sequence: DAVDCALDPLSETKCTLKS
Position: 287-305
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative

Epitope: S-306
Chemical type: Peptide from protein
Sequence: FTVEKGIYQTSNGGGTPCS
Assay category: BCell
Result: Negative

Epitope: S-588
Chemical type: Peptide from protein
Sequence: NGGGTPCSFGGVSVI
Assay category: BCell
Result: Negative

Epitope: S-524
Chemical type: Peptide from protein
Sequence: VCGPKKSTNLVKNKCVNFNFN
Position: 524-544
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative

Epitope: S-601
Chemical type: Peptide from protein
Sequence: GTNTSNQVAVL
Position: 601-611
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative

Epitope: N-61
Chemical type: Peptide from protein
Sequence: KEDLKFPRGQGVPIN
Position: 61-75
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Negative

Epitope: N-311
Chemical type: Peptide from protein
Sequence: ASAFFGMSRIGMEVT
Position: 311-325
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Negative

Epitope: N-41
Chemical type: Peptide from protein
Sequence: RPQGLPNNTASWFTALTQHGK
Position: 41-61
Source molecule (GenBank): P0DTC9.1
Assay category: BCell
Result: Positive

Epitope: S-I468T (+)
Chemical type: Peptide from protein
Sequence: LKPFERDTSTEIYQA
Position: 461-475
Source molecule (GenBank): QVO95873.1
Assay category: BCell
Result: Negative