Reference: Rony Dahan; John A Gebe; Anton Preisinger; Eddie A James; Mark Tendler; Gerald T Nepom; Yoram Reiter. "Antigen-specific immunomodulation for type 1 diabetes by novel recombinant antibodies directed against diabetes-associates auto-reactive T cell epitope." Journal of autoimmunity (2013).

Epitope: GAD-555-567
Chemical type: Peptide from protein
Sequence: NFFRMVISNPAAT
Position: 555-567
Source molecule (GenBank): Q05329.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 16200.0

Epitope: GAD-555-567
Chemical type: Peptide from protein
Sequence: NFFRMVISNPAAT
Position: 555-567
Source molecule (GenBank): Q05329.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 0.00104

Epitope: GAD-555-567
Chemical type: Peptide from protein
Sequence: NFFRMVISNPAAT
Position: 555-567
Source molecule (GenBank): Q05329.1
Assay category: BCell
Result: Positive

Epitope: GAD-555-567
Chemical type: Peptide from protein
Sequence: NFFRMVISNPAAT
Position: 555-567
Source molecule (GenBank): Q05329.1
Assay category: BCell
Result: Positive
Quantitative measurement: 64.0

Epitope: GAD-555-567
Chemical type: Peptide from protein
Sequence: NFFRMVISNPAAT
Position: 555-567
Source molecule (GenBank): Q05329.1
Assay category: BCell
Result: Positive

Epitope: GAD-555-567
Chemical type: Peptide from protein
Sequence: NFFRMVISNPAAT
Position: 555-567
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: GAD-555-567
Chemical type: Peptide from protein
Sequence: NFFRMVISNPAAT
Position: 555-567
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: GAD-555-567
Chemical type: Peptide from protein
Sequence: NFFRMVISNPAAT
Position: 555-567
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: GAD-555-567
Chemical type: Peptide from protein
Sequence: NFFRMVISNPAAT
Position: 555-567
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD-555-567
Chemical type: Peptide from protein
Sequence: NFFRMVISNPAAT
Position: 555-567
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD-555-567
Chemical type: Peptide from protein
Sequence: NFFRMVISNPAAT
Position: 555-567
Source molecule (GenBank): Q05329.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 11.0

Epitope: mAb G3H8 (I561)
Chemical type: Discontinuous protein residues
Discontinuous residues: I561
Source molecule (GenBank): Q05329.1
Assay category: BCell
Result: Positive
Quantitative measurement: 104.0

Epitope: mAb G3H8 (I561)
Chemical type: Discontinuous protein residues
Discontinuous residues: I561
Source molecule (GenBank): Q05329.1
Assay category: BCell
Result: Positive-High
Quantitative measurement: 908000.0

Epitope: mAb G3H8 (I561)
Chemical type: Discontinuous protein residues
Discontinuous residues: I561
Source molecule (GenBank): Q05329.1
Assay category: BCell
Result: Positive

Epitope: mAb G3H8 (I561)
Chemical type: Discontinuous protein residues
Discontinuous residues: I561
Source molecule (GenBank): Q05329.1
Assay category: BCell
Result: Positive

Epitope: mAb G3H8 (I561)
Chemical type: Discontinuous protein residues
Discontinuous residues: I561
Source molecule (GenBank): Q05329.1
Assay category: BCell
Result: Positive

Epitope: mAb G3H8 (I561)
Chemical type: Discontinuous protein residues
Discontinuous residues: I561
Source molecule (GenBank): Q05329.1
Assay category: BCell
Result: Positive-High
Quantitative measurement: 0.09

Epitope: 561M
Chemical type: Peptide, no natural source
Sequence: NFFRMVISMPAAT
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 12.0

Epitope: 563Q
Chemical type: Peptide, no natural source
Sequence: NFFRMVISNPQAT
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 20.0

Epitope: 559Z
Chemical type: Peptide, no natural source
Sequence: NFFRMVQSNPAAT
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 15.0

Epitope: 561M, 563Q
Chemical type: Peptide, no natural source
Sequence: NFFRMVISMPQAT
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 14.0