Reference: H M Diepolder; J T Gerlach; R Zachoval; R M Hoffmann; M C Jung; E A Wierenga; S Scholz; T Santantonio; M Houghton; S Southwood; A Sette; G R Pape. "Immunodominant CD4+ T-cell epitope within nonstructural protein 3 in acute hepatitis C virus infection." Journal of virology (1997).

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Host: F 36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Host:  38-64 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Host: F 36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Host: F 23 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Host: F 23 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Host:  38-64 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Host:  38-64 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Host:  38-64 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Host:  38-64 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: TCell
Result: Positive
Host:  38-64 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 1.4

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 33.0

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 266.0

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 141.0

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 21.0

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 4604.0

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 39.0

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 126.0

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 7.8

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1124.0

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 75.0

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 3.5

Epitope: NS3 1248-1261
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAAT
Position: 222-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 3695.0

Epitope: NS3 1388-1407
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKRKCDELATKL
Position: 1388-1407
Source molecule (GenBank): ACJ37193.1
Assay category: TCell
Result: Positive
Host:  18-38 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3 1388-1407
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKRKCDELATKL
Position: 1388-1407
Source molecule (GenBank): ACJ37193.1
Assay category: TCell
Result: Positive
Host: F 18 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3 1388-1407
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKRKCDELATKL
Position: 1388-1407
Source molecule (GenBank): ACJ37193.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 17391.0

Epitope: NS3 1388-1407
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKRKCDELATKL
Position: 1388-1407
Source molecule (GenBank): ACJ37193.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1388-1407
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKRKCDELATKL
Position: 1388-1407
Source molecule (GenBank): ACJ37193.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1887.0

Epitope: NS3 1388-1407
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKRKCDELATKL
Position: 1388-1407
Source molecule (GenBank): ACJ37193.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1388-1407
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKRKCDELATKL
Position: 1388-1407
Source molecule (GenBank): ACJ37193.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1388-1407
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKRKCDELATKL
Position: 1388-1407
Source molecule (GenBank): ACJ37193.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1388-1407
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKRKCDELATKL
Position: 1388-1407
Source molecule (GenBank): ACJ37193.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1388-1407
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKRKCDELATKL
Position: 1388-1407
Source molecule (GenBank): ACJ37193.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1388-1407
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKRKCDELATKL
Position: 1388-1407
Source molecule (GenBank): ACJ37193.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1388-1407
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKRKCDELATKL
Position: 1388-1407
Source molecule (GenBank): ACJ37193.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1388-1407
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKRKCDELATKL
Position: 1388-1407
Source molecule (GenBank): ACJ37193.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1388-1407
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKRKCDELATKL
Position: 1388-1407
Source molecule (GenBank): ACJ37193.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1388-1407
Chemical type: Peptide from protein
Sequence: GRHLIFCHSKRKCDELATKL
Position: 1388-1407
Source molecule (GenBank): ACJ37193.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1450-1469
Chemical type: Peptide from protein
Sequence: SVIDCNTCVTQTVDFSLDPT
Position: 424-443
Source molecule (GenBank): ABN45875.1
Assay category: TCell
Result: Positive
Host: F 64 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3 1450-1469
Chemical type: Peptide from protein
Sequence: SVIDCNTCVTQTVDFSLDPT
Position: 424-443
Source molecule (GenBank): ABN45875.1
Assay category: TCell
Result: Positive
Host: F 64 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NS3 1450-1469
Chemical type: Peptide from protein
Sequence: SVIDCNTCVTQTVDFSLDPT
Position: 424-443
Source molecule (GenBank): ABN45875.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1450-1469
Chemical type: Peptide from protein
Sequence: SVIDCNTCVTQTVDFSLDPT
Position: 424-443
Source molecule (GenBank): ABN45875.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1450-1469
Chemical type: Peptide from protein
Sequence: SVIDCNTCVTQTVDFSLDPT
Position: 424-443
Source molecule (GenBank): ABN45875.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 35000.0

Epitope: NS3 1450-1469
Chemical type: Peptide from protein
Sequence: SVIDCNTCVTQTVDFSLDPT
Position: 424-443
Source molecule (GenBank): ABN45875.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1450-1469
Chemical type: Peptide from protein
Sequence: SVIDCNTCVTQTVDFSLDPT
Position: 424-443
Source molecule (GenBank): ABN45875.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1450-1469
Chemical type: Peptide from protein
Sequence: SVIDCNTCVTQTVDFSLDPT
Position: 424-443
Source molecule (GenBank): ABN45875.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1450-1469
Chemical type: Peptide from protein
Sequence: SVIDCNTCVTQTVDFSLDPT
Position: 424-443
Source molecule (GenBank): ABN45875.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1450-1469
Chemical type: Peptide from protein
Sequence: SVIDCNTCVTQTVDFSLDPT
Position: 424-443
Source molecule (GenBank): ABN45875.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1450-1469
Chemical type: Peptide from protein
Sequence: SVIDCNTCVTQTVDFSLDPT
Position: 424-443
Source molecule (GenBank): ABN45875.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1450-1469
Chemical type: Peptide from protein
Sequence: SVIDCNTCVTQTVDFSLDPT
Position: 424-443
Source molecule (GenBank): ABN45875.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1450-1469
Chemical type: Peptide from protein
Sequence: SVIDCNTCVTQTVDFSLDPT
Position: 424-443
Source molecule (GenBank): ABN45875.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1450-1469
Chemical type: Peptide from protein
Sequence: SVIDCNTCVTQTVDFSLDPT
Position: 424-443
Source molecule (GenBank): ABN45875.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 12198.0

Epitope: NS3 1450-1469
Chemical type: Peptide from protein
Sequence: SVIDCNTCVTQTVDFSLDPT
Position: 424-443
Source molecule (GenBank): ABN45875.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: NS3 1242-1261
Chemical type: Peptide from protein
Sequence: AAYAAQGYKVLVLNPSVAAT
Position: 216-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 48.0

Epitope: NS3 1242-1261
Chemical type: Peptide from protein
Sequence: AAYAAQGYKVLVLNPSVAAT
Position: 216-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1234.0

Epitope: NS3 1242-1261
Chemical type: Peptide from protein
Sequence: AAYAAQGYKVLVLNPSVAAT
Position: 216-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 86.0

Epitope: NS3 1242-1261
Chemical type: Peptide from protein
Sequence: AAYAAQGYKVLVLNPSVAAT
Position: 216-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 96.0

Epitope: NS3 1242-1261
Chemical type: Peptide from protein
Sequence: AAYAAQGYKVLVLNPSVAAT
Position: 216-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 18.0

Epitope: NS3 1242-1261
Chemical type: Peptide from protein
Sequence: AAYAAQGYKVLVLNPSVAAT
Position: 216-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 483.0

Epitope: NS3 1242-1261
Chemical type: Peptide from protein
Sequence: AAYAAQGYKVLVLNPSVAAT
Position: 216-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1994.0

Epitope: NS3 1242-1261
Chemical type: Peptide from protein
Sequence: AAYAAQGYKVLVLNPSVAAT
Position: 216-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 60.0

Epitope: NS3 1242-1261
Chemical type: Peptide from protein
Sequence: AAYAAQGYKVLVLNPSVAAT
Position: 216-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 5258.0

Epitope: NS3 1242-1261
Chemical type: Peptide from protein
Sequence: AAYAAQGYKVLVLNPSVAAT
Position: 216-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2.9

Epitope: NS3 1242-1261
Chemical type: Peptide from protein
Sequence: AAYAAQGYKVLVLNPSVAAT
Position: 216-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 240.0

Epitope: NS3 1242-1261
Chemical type: Peptide from protein
Sequence: AAYAAQGYKVLVLNPSVAAT
Position: 216-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 103.0

Epitope: NS3 1242-1261
Chemical type: Peptide from protein
Sequence: AAYAAQGYKVLVLNPSVAAT
Position: 216-235
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 11.0

Epitope: NS3 1248-1267
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAATLGFGAY
Position: 222-241
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 4.1

Epitope: NS3 1248-1267
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAATLGFGAY
Position: 222-241
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 23.0

Epitope: NS3 1248-1267
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAATLGFGAY
Position: 222-241
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 3.5

Epitope: NS3 1248-1267
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAATLGFGAY
Position: 222-241
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1500.0

Epitope: NS3 1248-1267
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAATLGFGAY
Position: 222-241
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 8154.0

Epitope: NS3 1248-1267
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAATLGFGAY
Position: 222-241
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 9.7

Epitope: NS3 1248-1267
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAATLGFGAY
Position: 222-241
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 80.0

Epitope: NS3 1248-1267
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAATLGFGAY
Position: 222-241
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 2454.0

Epitope: NS3 1248-1267
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAATLGFGAY
Position: 222-241
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 19.0

Epitope: NS3 1248-1267
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAATLGFGAY
Position: 222-241
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 240.0

Epitope: NS3 1248-1267
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAATLGFGAY
Position: 222-241
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 42.0

Epitope: NS3 1248-1267
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAATLGFGAY
Position: 222-241
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 9480.0

Epitope: NS3 1248-1267
Chemical type: Peptide from protein
Sequence: GYKVLVLNPSVAATLGFGAY
Position: 222-241
Source molecule (GenBank): NP_803144.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 20.0