Reference: Zhiyuan Mao; Pavlo A Nesterenko; Jami McLaughlin; Weixian Deng; Giselle Burton Sojo; Donghui Cheng; Miyako Noguchi; William Chour; Diana C DeLucia; Kathryn A Finton; Yu Qin; Matthew B Obusan; Wendy Tran; Liang Wang; Nathanael J Bangayan; Lisa Ta; Chia-Chun Chen; Christopher S Seet; Gay M Crooks; John W Phillips; James R Heath; Roland K Strong; John K Lee; James A Wohlschlegel; Owen N Witte. "Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation." Proceedings of the National Academy of Sciences of the United States of America (2022).

Epitope: PAP_A2_14
Chemical type: Peptide from protein
Sequence: ILLWQPIPV
Position: 135-143
Source molecule (GenBank): P15309.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: PAP_A2_14
Chemical type: Peptide from protein
Sequence: ILLWQPIPV
Position: 135-143
Source molecule (GenBank): P15309.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: PAP_A2_14
Chemical type: Peptide from protein
Sequence: ILLWQPIPV
Position: 135-143
Source molecule (GenBank): P15309.3
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: PAP_A2_14
Chemical type: Peptide from protein
Sequence: ILLWQPIPV
Position: 135-143
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_14
Chemical type: Peptide from protein
Sequence: ILLWQPIPV
Position: 135-143
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Positive

Epitope: PAP_A2_22
Chemical type: Peptide from protein
Sequence: TLMSAMTNL
Position: 112-120
Source molecule (GenBank): P15309.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: PAP_A2_22
Chemical type: Peptide from protein
Sequence: TLMSAMTNL
Position: 112-120
Source molecule (GenBank): P15309.3
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: PAP_A2_22
Chemical type: Peptide from protein
Sequence: TLMSAMTNL
Position: 112-120
Source molecule (GenBank): P15309.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: PAP_A2_22
Chemical type: Peptide from protein
Sequence: TLMSAMTNL
Position: 112-120
Source molecule (GenBank): P15309.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: PAP_A2_22
Chemical type: Peptide from protein
Sequence: TLMSAMTNL
Position: 112-120
Source molecule (GenBank): P15309.3
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: PAP_A2_22
Chemical type: Peptide from protein
Sequence: TLMSAMTNL
Position: 112-120
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_22
Chemical type: Peptide from protein
Sequence: TLMSAMTNL
Position: 112-120
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_22
Chemical type: Peptide from protein
Sequence: TLMSAMTNL
Position: 112-120
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Positive

Epitope: PAP_A2_27
Chemical type: Peptide from protein
Sequence: VLAKELKFV
Position: 30-38
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_27
Chemical type: Peptide from protein
Sequence: VLAKELKFV
Position: 30-38
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Positive

Epitope: PAP_A2_24
Chemical type: Peptide from protein
Sequence: SVHNFTLPSW
Position: 217-226
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_24
Chemical type: Peptide from protein
Sequence: SVHNFTLPSW
Position: 217-226
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Positive

Epitope: PAP_A2_25
Chemical type: Peptide from protein
Sequence: IMYSAHDTTV
Position: 284-293
Source molecule (GenBank): P15309.3
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PAP_A2_25
Chemical type: Peptide from protein
Sequence: IMYSAHDTTV
Position: 284-293
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_25
Chemical type: Peptide from protein
Sequence: IMYSAHDTTV
Position: 284-293
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Positive

Epitope: PAP_A2_20
Chemical type: Peptide from protein
Sequence: KVYDPLYCESV
Position: 208-218
Source molecule (GenBank): P15309.3
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PAP_A2_20
Chemical type: Peptide from protein
Sequence: KVYDPLYCESV
Position: 208-218
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_20
Chemical type: Peptide from protein
Sequence: KVYDPLYCESV
Position: 208-218
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Positive

Epitope: PAP_A2_21
Chemical type: Peptide from protein
Sequence: LLLARAASLSL
Position: 6-16
Source molecule (GenBank): P15309.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: PAP_A2_21
Chemical type: Peptide from protein
Sequence: LLLARAASLSL
Position: 6-16
Source molecule (GenBank): P15309.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: PAP_A2_21
Chemical type: Peptide from protein
Sequence: LLLARAASLSL
Position: 6-16
Source molecule (GenBank): P15309.3
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: PAP_A2_21
Chemical type: Peptide from protein
Sequence: LLLARAASLSL
Position: 6-16
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_21
Chemical type: Peptide from protein
Sequence: LLLARAASLSL
Position: 6-16
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Positive

Epitope: PAP_A2_15
Chemical type: Peptide from protein
Sequence: WQPIPVHTVPLS
Position: 138-149
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_15
Chemical type: Peptide from protein
Sequence: WQPIPVHTVPLS
Position: 138-149
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Positive

Epitope: PAP_A2_23
Chemical type: Peptide from protein
Sequence: LLFFWLDRSVLA
Position: 21-32
Source molecule (GenBank): P15309.3
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PAP_A2_23
Chemical type: Peptide from protein
Sequence: LLFFWLDRSVLA
Position: 21-32
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_23
Chemical type: Peptide from protein
Sequence: LLFFWLDRSVLA
Position: 21-32
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Negative

Epitope: PAP_A2_2
Chemical type: Peptide from protein
Sequence: YSAHDTTVSGLQM
Position: 286-298
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_2
Chemical type: Peptide from protein
Sequence: YSAHDTTVSGLQM
Position: 286-298
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Positive

Epitope: PAP_A2_1
Chemical type: Peptide from protein
Sequence: YSAHDTTVSGLQMA
Position: 286-299
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_1
Chemical type: Peptide from protein
Sequence: YSAHDTTVSGLQMA
Position: 286-299
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Positive

Epitope: PAP_A2_4
Chemical type: Peptide from protein
Sequence: DFIATLGKLSG
Position: 186-196
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_4
Chemical type: Peptide from protein
Sequence: DFIATLGKLSG
Position: 186-196
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Negative

Epitope: PAP_A2_5
Chemical type: Peptide from protein
Sequence: DFIATLGK
Position: 186-193
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_5
Chemical type: Peptide from protein
Sequence: DFIATLGK
Position: 186-193
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Negative

Epitope: PAP_A2_6
Chemical type: Peptide from protein
Sequence: IATLGKLSGLHGQDL
Position: 188-202
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_6
Chemical type: Peptide from protein
Sequence: IATLGKLSGLHGQDL
Position: 188-202
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_6
Chemical type: Peptide from protein
Sequence: IATLGKLSGLHGQDL
Position: 188-202
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Negative

Epitope: PAP_A2_7
Chemical type: Peptide from protein
Sequence: IATLGKLSGLHGQD
Position: 188-201
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_7
Chemical type: Peptide from protein
Sequence: IATLGKLSGLHGQD
Position: 188-201
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Negative

Epitope: PAP_A2_8
Chemical type: Peptide from protein
Sequence: LSGLHGQDL
Position: 194-202
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_8
Chemical type: Peptide from protein
Sequence: LSGLHGQDL
Position: 194-202
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Negative

Epitope: PAP_A2_9
Chemical type: Peptide from protein
Sequence: MEQHYELGEY
Position: 75-84
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_9
Chemical type: Peptide from protein
Sequence: MEQHYELGEY
Position: 75-84
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Negative

Epitope: PAP_A2_10
Chemical type: Peptide from protein
Sequence: GEYFVEMYYR
Position: 323-332
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_10
Chemical type: Peptide from protein
Sequence: GEYFVEMYYR
Position: 323-332
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Negative

Epitope: PAP_A2_11
Chemical type: Peptide from protein
Sequence: SPIDTFPTDPIK
Position: 48-59
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_11
Chemical type: Peptide from protein
Sequence: SPIDTFPTDPIK
Position: 48-59
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_11
Chemical type: Peptide from protein
Sequence: SPIDTFPTDPIK
Position: 48-59
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Negative

Epitope: PAP_A2_12
Chemical type: Peptide from protein
Sequence: FQKRLHPYK
Position: 177-185
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_12
Chemical type: Peptide from protein
Sequence: FQKRLHPYK
Position: 177-185
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Negative

Epitope: PAP_A2_13
Chemical type: Peptide from protein
Sequence: IRSTDVDRTL
Position: 104-113
Source molecule (GenBank): P15309.3
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PAP_A2_13
Chemical type: Peptide from protein
Sequence: IRSTDVDRTL
Position: 104-113
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_13
Chemical type: Peptide from protein
Sequence: IRSTDVDRTL
Position: 104-113
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_13
Chemical type: Peptide from protein
Sequence: IRSTDVDRTL
Position: 104-113
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Negative

Epitope: PAP_A2_17
Chemical type: Peptide from protein
Sequence: KELKFVTL
Position: 33-40
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_17
Chemical type: Peptide from protein
Sequence: KELKFVTL
Position: 33-40
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_17
Chemical type: Peptide from protein
Sequence: KELKFVTL
Position: 33-40
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Negative

Epitope: PAP_A2_18
Chemical type: Peptide from protein
Sequence: KELKFVTLVFRHGD
Position: 33-46
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_18
Chemical type: Peptide from protein
Sequence: KELKFVTLVFRHGD
Position: 33-46
Source molecule (GenBank): P15309.3
Assay category: MhcLigandElution
Result: Positive

Epitope: PAP_A2_18
Chemical type: Peptide from protein
Sequence: KELKFVTLVFRHGD
Position: 33-46
Source molecule (GenBank): P15309.3
Assay category: MhcBinding
Result: Negative