Reference: Jinghe Huang; Byong H Kang; Elise Ishida; Tongqing Zhou; Trevor Griesman; Zizhang Sheng; Fan Wu; Nicole A Doria-Rose; Baoshan Zhang; Krisha McKee; Sijy O'Dell; Gwo-Yu Chuang; Aliaksandr Druz; Ivelin S Georgiev; Chaim A Schramm; Anqi Zheng; M Gordon Joyce; Mangaiarkarasi Asokan; Amy Ransier; Sam Darko; Stephen A Migueles; Robert T Bailer; Mark K Louder; S Munir Alam; Robert Parks; Garnett Kelsoe; Tarra Von Holle; Barton F Haynes; Daniel C Douek; Vanessa Hirsch; Michael S Seaman; Lawrence Shapiro; John R Mascola; Peter D Kwong; Mark Connors. "Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth." Immunity (2016).

Epitope: Epitope of N6 Fab on HIV-1 clade G strain X2088 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: T274, N275, N276, A277, K278, N352, A364, G365, G366, D367, E369, I370, R417, M418, W419, V422, R448, D449, G450, V451, N452, D453, T454, R463, G467, D468, R470
Source molecule (GenBank): ACJ68899.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.75

Epitope: Epitope of N6 Fab on HIV-1 clade G strain X2088 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: T274, N275, N276, A277, K278, N352, A364, G365, G366, D367, E369, I370, R417, M418, W419, V422, R448, D449, G450, V451, N452, D453, T454, R463, G467, D468, R470
Source molecule (GenBank): ACJ68899.1
Assay category: BCell
Result: Positive

Epitope: Epitope of N6 Fab on HIV-1 clade G strain X2088 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: T274, N275, N276, A277, K278, N352, A364, G365, G366, D367, E369, I370, R417, M418, W419, V422, R448, D449, G450, V451, N452, D453, T454, R463, G467, D468, R470
Source molecule (GenBank): ACJ68899.1
Assay category: BCell
Result: Positive
Quantitative measurement: 9.9

Epitope: Epitope of N6 Fab on HIV-1 clade A/E strain 93TH057 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, L121, E277, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, G423, T424, G425, Q426, T449, R450, D451, G452, A454, N455, R463, G467
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.59

Epitope: Epitope of N6 Fab on HIV-1 clade A/E strain 93TH057 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, L121, E277, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, G423, T424, G425, Q426, T449, R450, D451, G452, A454, N455, R463, G467
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.4

Epitope: Epitope of N6 Fab on HIV-1 clade A/E strain 93TH057 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, L121, E277, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, G423, T424, G425, Q426, T449, R450, D451, G452, A454, N455, R463, G467
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of N6 Fab on HIV-1 clade C DU172 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, T286, N287, N288, A289, K290, S371, G372, G373, D374, E376, I377, R422, M423, W424, V427, R453, D454, G455, G456, K457, R466, G470, D471, R473
Source molecule (GenBank): ABD83638.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.81

Epitope: Epitope of N6 Fab on HIV-1 clade C DU172 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, T286, N287, N288, A289, K290, S371, G372, G373, D374, E376, I377, R422, M423, W424, V427, R453, D454, G455, G456, K457, R466, G470, D471, R473
Source molecule (GenBank): ABD83638.1
Assay category: BCell
Result: Positive

Epitope: Epitope of N6 Fab on HIV-1 clade C DU172 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, T286, N287, N288, A289, K290, S371, G372, G373, D374, E376, I377, R422, M423, W424, V427, R453, D454, G455, G456, K457, R466, G470, D471, R473
Source molecule (GenBank): ABD83638.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.15