Reference: Nicole V Johnson; Revina C van Scherpenzeel; Mark J G Bakkers; Ajit R Ramamohan; Daan van Overveld; Lam Le; Johannes P M Langedijk; Joost A Kolkman; Jason S McLellan. "Structural basis for potent neutralization of human respirovirus type 3 by protective single-domain camelid antibodies." Nature communications (2024).

Epitope: Epitope of VHH 1D10 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: Q19, I20, D21, N290, K319, G320, A321, F322, L323, G345, V347, H350, E353, S354, S357, N359; B: Q304, N305, R306
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH 1D10 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: Q19, I20, D21, N290, K319, G320, A321, F322, L323, G345, V347, H350, E353, S354, S357, N359; B: Q304, N305, R306
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0678

Epitope: Epitope of VHH 1D10 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: Q19, I20, D21, N290, K319, G320, A321, F322, L323, G345, V347, H350, E353, S354, S357, N359; B: Q304, N305, R306
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2100000.0

Epitope: Epitope of VHH 1D10 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: Q19, I20, D21, N290, K319, G320, A321, F322, L323, G345, V347, H350, E353, S354, S357, N359; B: Q304, N305, R306
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00014

Epitope: Epitope of VHH 1D10 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: Q19, I20, D21, N290, K319, G320, A321, F322, L323, G345, V347, H350, E353, S354, S357, N359; B: Q304, N305, R306
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH 1D10 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: Q19, I20, D21, N290, K319, G320, A321, F322, L323, G345, V347, H350, E353, S354, S357, N359; B: Q304, N305, R306
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH 1D10 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: Q19, I20, D21, N290, K319, G320, A321, F322, L323, G345, V347, H350, E353, S354, S357, N359; B: Q304, N305, R306
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH 4C06 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I397, N423, G424, M425; B: Q42, N43, F44, E45, T46, Y48, E108, R109, F110, F111, G112, G113, V114, I115, T129, V132, V135, E136, Q139, L284
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH 4C06 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I397, N423, G424, M425; B: Q42, N43, F44, E45, T46, Y48, E108, R109, F110, F111, G112, G113, V114, I115, T129, V132, V135, E136, Q139, L284
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0752

Epitope: Epitope of VHH 4C06 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I397, N423, G424, M425; B: Q42, N43, F44, E45, T46, Y48, E108, R109, F110, F111, G112, G113, V114, I115, T129, V132, V135, E136, Q139, L284
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive
Quantitative measurement: 490000.0

Epitope: Epitope of VHH 4C06 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I397, N423, G424, M425; B: Q42, N43, F44, E45, T46, Y48, E108, R109, F110, F111, G112, G113, V114, I115, T129, V132, V135, E136, Q139, L284
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH 4C06 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I397, N423, G424, M425; B: Q42, N43, F44, E45, T46, Y48, E108, R109, F110, F111, G112, G113, V114, I115, T129, V132, V135, E136, Q139, L284
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH 4C06 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I397, N423, G424, M425; B: Q42, N43, F44, E45, T46, Y48, E108, R109, F110, F111, G112, G113, V114, I115, T129, V132, V135, E136, Q139, L284
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000037

Epitope: Epitope of VHH 4C06 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I397, N423, G424, M425; B: Q42, N43, F44, E45, T46, Y48, E108, R109, F110, F111, G112, G113, V114, I115, T129, V132, V135, E136, Q139, L284
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH 4C06 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I397, N423, G424, M425; B: Q42, N43, F44, E45, T46, Y48, E108, R109, F110, F111, G112, G113, V114, I115, T129, V132, V135, E136, Q139, L284
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH 4C06 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I397, N423, G424, M425; B: Q42, N43, F44, E45, T46, Y48, E108, R109, F110, F111, G112, G113, V114, I115, T129, V132, V135, E136, Q139, L284
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH 4C03 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: Y251, I253, R287, F335, S336; B: R73, D76, I80, Y83, D84, R87, D91, L271, Y274
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH 4C03 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: Y251, I253, R287, F335, S336; B: R73, D76, I80, Y83, D84, R87, D91, L271, Y274
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH 4C03 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: Y251, I253, R287, F335, S336; B: R73, D76, I80, Y83, D84, R87, D91, L271, Y274
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH 4C03 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: Y251, I253, R287, F335, S336; B: R73, D76, I80, Y83, D84, R87, D91, L271, Y274
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0168

Epitope: Epitope of VHH 4C03 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: Y251, I253, R287, F335, S336; B: R73, D76, I80, Y83, D84, R87, D91, L271, Y274
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive
Quantitative measurement: 130000.0

Epitope: Epitope of VHH 4C03 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: Y251, I253, R287, F335, S336; B: R73, D76, I80, Y83, D84, R87, D91, L271, Y274
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000021

Epitope: Epitope of VHH 4C03 on RV3 F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: Y251, I253, R287, F335, S336; B: R73, D76, I80, Y83, D84, R87, D91, L271, Y274
Source molecule (GenBank): ARQ32975.1
Assay category: BCell
Result: Positive