Reference: James T Earnest; Autumn C Holmes; Katherine Basore; Matthias Mack; Daved H Fremont; Michael S Diamond. "The mechanistic basis of protection by non-neutralizing anti-alphavirus antibodies." Cell reports (2021).

Epitope: Group A -MAY-23
Chemical type: Peptide from protein
Sequence: SCH
Position: 351-353
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group A -MAY-23
Chemical type: Peptide from protein
Sequence: SCH
Position: 351-353
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Quantitative measurement: 18.4
Host: F 10 weeks

Epitope: Group A -MAY-23
Chemical type: Peptide from protein
Sequence: SCH
Position: 351-353
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive-Intermediate
Host: F 10 weeks

Epitope: Group A -MAY-23
Chemical type: Peptide from protein
Sequence: SCH
Position: 351-353
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group A -MAY-23
Chemical type: Peptide from protein
Sequence: SCH
Position: 351-353
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group B -MAY-8
Chemical type: Peptide from protein
Sequence: TKTDT
Position: 381-385
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group B -MAY-8
Chemical type: Peptide from protein
Sequence: TKTDT
Position: 381-385
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Quantitative measurement: 16.6
Host: F 10 weeks

Epitope: Group B -MAY-8
Chemical type: Peptide from protein
Sequence: TKTDT
Position: 381-385
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive-Intermediate
Host: F 10 weeks

Epitope: Group B -MAY-8
Chemical type: Peptide from protein
Sequence: TKTDT
Position: 381-385
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group B -MAY-8
Chemical type: Peptide from protein
Sequence: TKTDT
Position: 381-385
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group B -MAY-10
Chemical type: Peptide from protein
Sequence: TKTD
Position: 381-384
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group B -MAY-10
Chemical type: Peptide from protein
Sequence: TKTD
Position: 381-384
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group B -MAY-10
Chemical type: Peptide from protein
Sequence: TKTD
Position: 381-384
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group B -MAY-10
Chemical type: Peptide from protein
Sequence: TKTD
Position: 381-384
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group B -MAY-10
Chemical type: Peptide from protein
Sequence: TKTD
Position: 381-384
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Quantitative measurement: 14.0
Host: F 10 weeks

Epitope: Group B -MAY-10
Chemical type: Peptide from protein
Sequence: TKTD
Position: 381-384
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group B -MAY-10
Chemical type: Peptide from protein
Sequence: TKTD
Position: 381-384
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group C -MAY-60
Chemical type: Discontinuous protein residues
Discontinuous residues: G396, D398, I399, A400, E401
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group C -MAY-60
Chemical type: Discontinuous protein residues
Discontinuous residues: G396, D398, I399, A400, E401
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group C -MAY-60
Chemical type: Discontinuous protein residues
Discontinuous residues: G396, D398, I399, A400, E401
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group C -MAY-60
Chemical type: Discontinuous protein residues
Discontinuous residues: G396, D398, I399, A400, E401
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive-Low
Host: F 10 weeks

Epitope: Group D -MAY-27/41/68/112
Chemical type: Discontinuous protein residues
Discontinuous residues: S405, T406, K408, H410
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Quantitative measurement: 110.5
Host: F 10 weeks

Epitope: Group D -MAY-27/41/68/112
Chemical type: Discontinuous protein residues
Discontinuous residues: S405, T406, K408, H410
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group D -MAY-27/41/68/112
Chemical type: Discontinuous protein residues
Discontinuous residues: S405, T406, K408, H410
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Quantitative measurement: 47.3
Host: F 10 weeks

Epitope: Group D -MAY-27/41/68/112
Chemical type: Discontinuous protein residues
Discontinuous residues: S405, T406, K408, H410
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group D -MAY-27/41/68/112
Chemical type: Discontinuous protein residues
Discontinuous residues: S405, T406, K408, H410
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive-Low
Host: F 10 weeks

Epitope: Group D -MAY-27/41/68/112
Chemical type: Discontinuous protein residues
Discontinuous residues: S405, T406, K408, H410
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group D -MAY-39
Chemical type: Discontinuous protein residues
Discontinuous residues: T406, K408, H410
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group D -MAY-39
Chemical type: Discontinuous protein residues
Discontinuous residues: T406, K408, H410
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Quantitative measurement: 547.6
Host: F 10 weeks

Epitope: Group D -MAY-39
Chemical type: Discontinuous protein residues
Discontinuous residues: T406, K408, H410
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group D -MAY-39
Chemical type: Discontinuous protein residues
Discontinuous residues: T406, K408, H410
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive-Low
Host: F 10 weeks

Epitope: Group E -MAY-108
Chemical type: Discontinuous protein residues
Discontinuous residues: T483, T484, K486, T487
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group E -MAY-108
Chemical type: Discontinuous protein residues
Discontinuous residues: T483, T484, K486, T487
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group E -MAY-108
Chemical type: Discontinuous protein residues
Discontinuous residues: T483, T484, K486, T487
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group E -MAY-108
Chemical type: Discontinuous protein residues
Discontinuous residues: T483, T484, K486, T487
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group E -MAY-108
Chemical type: Discontinuous protein residues
Discontinuous residues: T483, T484, K486, T487
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group E -MAY-108
Chemical type: Discontinuous protein residues
Discontinuous residues: T483, T484, K486, T487
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.1
Host: F 10 weeks

Epitope: Group E -MAY-108
Chemical type: Discontinuous protein residues
Discontinuous residues: T483, T484, K486, T487
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group F -MAY-72
Chemical type: Discontinuous protein residues
Discontinuous residues: D492, H494, M495, P497
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group F -MAY-72
Chemical type: Discontinuous protein residues
Discontinuous residues: D492, H494, M495, P497
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group F -MAY-72
Chemical type: Discontinuous protein residues
Discontinuous residues: D492, H494, M495, P497
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Quantitative measurement: 165.6
Host: F 10 weeks

Epitope: Group F -MAY-72
Chemical type: Discontinuous protein residues
Discontinuous residues: D492, H494, M495, P497
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Group F -MAY-72
Chemical type: Discontinuous protein residues
Discontinuous residues: D492, H494, M495, P497
Source molecule (GenBank): AAO33335.1
Assay category: BCell
Result: Positive-Low
Host: F 10 weeks