Reference: Agnieszka Sulima; Rashmi Jalah; Joshua F G Antoline; Oscar B Torres; Gregory H Imler; Jeffrey R Deschamps; Zoltan Beck; Carl R Alving; Arthur E Jacobson; Kenner C Rice; Gary R Matyas. "A Stable Heroin Analogue That Can Serve as a Vaccine Hapten to Induce Antibodies That Block the Effects of Heroin and Its Metabolites in Rodents and That Cross-React Immunologically with Related Drugs of Abuse." Journal of medicinal chemistry (2018).

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 3720.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 1500.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 217000.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 23800.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 53600.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 192900.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 17200.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 144600.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 14700.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 3000.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 7100.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 35500.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 104400.0
Host: M 9 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 3400.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 523900.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 3800.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 534600.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 5100.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 125500.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 3600.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 25000.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 1270.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 2360.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 28000.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 112430.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: 6-AMHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 24300.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 104400.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 110400.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 59700.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 9700.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 411000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 19700.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: MorHap
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: heroin
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 3000.0
Host: M 9 weeks

Epitope: heroin
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: F 7 weeks

Epitope: heroin
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: M 9 weeks

Epitope: heroin
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: heroin
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: F 7 weeks

Epitope: heroin
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 1270.0
Host: F 7 weeks

Epitope: M3-G
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: M3-G
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 28000.0
Host: F 7 weeks

Epitope: M3-G
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 35500.0
Host: M 9 weeks

Epitope: M-6G
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 104400.0
Host: M 9 weeks

Epitope: M-6G
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 411000.0
Host: F 7 weeks

Epitope: M-6G
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 25000.0
Host: F 7 weeks

Epitope: normorphine
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 112430.0
Host: F 7 weeks

Epitope: normorphine
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 192900.0
Host: M 9 weeks

Epitope: normorphine
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 19700.0
Host: F 7 weeks

Epitope: codeine
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 3800.0
Host: F 7 weeks

Epitope: codeine
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 17200.0
Host: M 9 weeks

Epitope: codeine
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: oxycodone
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 144600.0
Host: M 9 weeks

Epitope: oxycodone
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 534600.0
Host: F 7 weeks

Epitope: oxycodone
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: hydrocodone
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 5100.0
Host: F 7 weeks

Epitope: hydrocodone
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 14700.0
Host: M 9 weeks

Epitope: hydrocodone
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Quantitative measurement: 1000000.0
Host: F 7 weeks

Epitope: oxymorphone
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 110400.0
Host: F 7 weeks

Epitope: oxymorphone
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 217000.0
Host: M 9 weeks

Epitope: oxymorphone
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 125500.0
Host: F 7 weeks

Epitope: hydromorphone
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 3600.0
Host: F 7 weeks

Epitope: hydromorphone
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 23800.0
Host: M 9 weeks

Epitope: hydromorphone
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 59700.0
Host: F 7 weeks

Epitope: morphine
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 7100.0
Host: M 9 weeks

Epitope: morphine
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive

Epitope: morphine
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive

Epitope: morphine
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-High
Quantitative measurement: 2360.0
Host: F 7 weeks