LiteFold/IEDB huggingface dataset:
Reference: Francesca Urselli; Alloysius Gomez; Matthew D Gray; Caroline E Cameron; Justin J Taylor. "Identification of antibodies induced by immunization with the syphilis vaccine candidate Tp0751." Vaccine (2025).

Epitope: Tp0751 99-114
Chemical type: Peptide from protein
Sequence: VQTAMRIALWNRATHG
Position: 99-114
Source molecule (GenBank): AAC65720.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Tp0751 99-114
Chemical type: Peptide from protein
Sequence: VQTAMRIALWNRATHG
Position: 99-114
Source molecule (GenBank): AAC65720.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Tp0751 99-114
Chemical type: Peptide from protein
Sequence: VQTAMRIALWNRATHG
Position: 99-114
Source molecule (GenBank): AAC65720.1
Assay category: BCell
Result: Positive
Host: M
Reference: Alexandra Francian; Yevel Flores-Garcia; John R Powell; Nikolai Petrovsky; Fidel Zavala; Bryce Chackerian. "Virus-like particle-based vaccines targeting the  mosquito salivary protein TRIO." mSphere (2025).

Epitope: AgTRIO
Chemical type: Peptide from protein
Sequence: VDDLMAKFN
Position: 359-367
Source molecule (GenBank): AAL68795.1
Assay category: BCell
Result: Positive
Host: F 4-6 weeks

Epitope: AgTRIO
Chemical type: Peptide from protein
Sequence: VDDLMAKFN
Position: 359-367
Source molecule (GenBank): AAL68795.1
Assay category: BCell
Result: Positive
Host: F 4-6 weeks

Epitope: AgTRIO
Chemical type: Peptide from protein
Sequence: VDDLMAKFN
Position: 359-367
Source molecule (GenBank): AAL68795.1
Assay category: BCell
Result: Positive
Host: F 4-6 weeks

Epitope: AgTRIO
Chemical type: Peptide from protein
Sequence: VDDLMAKFN
Position: 359-367
Source molecule (GenBank): AAL68795.1
Assay category: BCell
Result: Positive
Host: F 4-6 weeks

Epitope: AsTRIO
Chemical type: Peptide from protein
Sequence: AANLRDKFN
Position: 354-362
Source molecule (GenBank): AAO74841.1
Assay category: BCell
Result: Positive
Host: F 4-6 weeks

Epitope: AsTRIO
Chemical type: Peptide from protein
Sequence: AANLRDKFN
Position: 354-362
Source molecule (GenBank): AAO74841.1
Assay category: BCell
Result: Positive-Low
Host: F 6-8 weeks

Epitope: AsTRIO
Chemical type: Peptide from protein
Sequence: AANLRDKFN
Position: 354-362
Source molecule (GenBank): AAO74841.1
Assay category: BCell
Result: Positive
Host: F 4-6 weeks

Epitope: AsTRIO
Chemical type: Peptide from protein
Sequence: AANLRDKFN
Position: 354-362
Source molecule (GenBank): AAO74841.1
Assay category: BCell
Result: Positive
Host: F 4-6 weeks

Epitope: AsTRIO
Chemical type: Peptide from protein
Sequence: AANLRDKFN
Position: 354-362
Source molecule (GenBank): AAO74841.1
Assay category: BCell
Result: Positive
Host: F 4-6 weeks
Reference: John M Hickey; Nitya Sharma; Max Fairlamb; Jennifer Doering; Yetunde Adewunmi; Katherine Prieto; Giulia Costa; Benjamin Wizel; Elena A Levashina; Nicholas J Mantis; Jean-Philippe Julien; Sangeeta B Joshi; David B Volkin. "PfCSP-ferritin nanoparticle malaria vaccine antigen formulated with aluminum-salt and CpG 1018® adjuvants: Preformulation characterization, antigen-adjuvant interactions, and mouse immunogenicity studies." Human vaccines & immunotherapeutics (2025).

Epitope: NANP5
Chemical type: Peptide from protein
Sequence: NANPNANPNANPNANPNANP
Position: 129-148
Source molecule (GenBank): P19597.2
Assay category: BCell
Result: Positive
Host: F

Epitope: Junc-1
Chemical type: Peptide from protein
Sequence: NPDPNANPNVDPNANP
Position: 101-116
Source molecule (GenBank): P19597.2
Assay category: BCell
Result: Positive
Host: F
Reference: Tadafumi Iino; Atsuhiko Hasegawa; Takaji Matsutani; Koichi Akashi; Mari Kannagi; Youko Suehiro. "Elimination of residual adult T-cell leukaemia clones by Tax-targeted dendritic cell vaccine." EJHaem (2025).

Epitope: Tax 11-19
Chemical type: Peptide from protein
Sequence: LLFGYPVYV
Position: 11-19
Source molecule (GenBank): AYN25353.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Tax 11-19
Chemical type: Peptide from protein
Sequence: LLFGYPVYV
Position: 11-19
Source molecule (GenBank): AYN25353.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Tax 11-19
Chemical type: Peptide from protein
Sequence: LLFGYPVYV
Position: 11-19
Source molecule (GenBank): AYN25353.1
Assay category: TCell
Result: Positive
Reference: Zhixiong Cai; Zhenli Li; Wenting Zhong; Fangzhou Lin; Xiuqing Dong; Honghao Ye; Yutong Guo; Geng Chen; Xiaoling Yu; Haijun Yu; Ruijing Tang; Xiaolong Liu. "Targeting Mesothelin Enhances Personalized Neoantigen Vaccine Induced Antitumor Immune Response in Orthotopic Pancreatic Cancer Mouse Models." Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2025).

Epitope: Daglb G238C
Chemical type: Peptide, no natural source
Sequence: LVPSDIAACFTLLHQQQ
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Smc5 V744F
Chemical type: Peptide, no natural source
Sequence: STKIKEINFQKAKLVTE
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Plekhm1 E573D
Chemical type: Peptide, no natural source
Sequence: GIWKEFFCDLSPLEFRL
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Slc16a13 H240N
Chemical type: Peptide, no natural source
Sequence: IPYVHLVANLQDLGWDP
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Ercc4 R183L
Chemical type: Peptide, no natural source
Sequence: FCHVERVMLNLFVRKLY
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Eftud2 G424C
Chemical type: Peptide, no natural source
Sequence: RLVCKKFFCEFTGFVDM
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Fundc2 K91N
Chemical type: Peptide, no natural source
Sequence: LANHTGYINVDWQRVEK
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cant1 W127L
Chemical type: Peptide, no natural source
Sequence: SRAQEENTLFSYLKKGY
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Usp28 W631L
Chemical type: Peptide, no natural source
Sequence: DISVTESSLEELERDSY
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Dip2b D558H
Chemical type: Peptide, no natural source
Sequence: GETVVNVLHFKKDAGLW
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Pnpla7 W1153C
Chemical type: Peptide, no natural source
Sequence: GWWLLWKRCNPLATKVK
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Pfkm A389S
Chemical type: Peptide, no natural source
Sequence: NWEVYKLLSHVRPPVSK
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Tubgcp4 A395G
Chemical type: Peptide, no natural source
Sequence: VTEHDVNVGFQQSAHKV
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Zfp26 F352L
Chemical type: Peptide, no natural source
Sequence: YECKKCEKLFTHPVYLN
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo
Reference: Sky T H Ng; Michael J Price; Naomi Richardson; Maher Nawaf; Alastair Copland; Heather B Streeter; Parth Narendran; David C Wraith. "Preclinical Development of a Tolerogenic Peptide From Glutamate Decarboxylase as a Candidate for Antigen-Specific Immunotherapy in Type 1 Diabetes." Diabetes (2025).

Epitope: P10
Chemical type: Peptide from protein
Sequence: DAAWGGGLLMSRKHKWKLSGVERANSVTWN
Position: 198-227
Source molecule (GenBank): Q9UGI5.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: P10
Chemical type: Peptide from protein
Sequence: DAAWGGGLLMSRKHKWKLSGVERANSVTWN
Position: 198-227
Source molecule (GenBank): Q9UGI5.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 63 57
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P10
Chemical type: Peptide from protein
Sequence: DAAWGGGLLMSRKHKWKLSGVERANSVTWN
Position: 198-227
Source molecule (GenBank): Q9UGI5.1
Assay category: TCell
Result: Positive-High
MHC allele types: 57 63 420 425 408 414 52 413 419 407
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP Ac1-9[4Y]
Chemical type: Peptide, no natural source
Sequence: ASQYRPSQR
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MBP Ac1-9[4Y]
Chemical type: Peptide, no natural source
Sequence: ASQYRPSQR
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MBP Ac1-9[4Y]
Chemical type: Peptide, no natural source
Sequence: ASQYRPSQR
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MBP Ac1-9[4Y]
Chemical type: Peptide, no natural source
Sequence: ASQYRPSQR
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo
Reference: Songsong Jiang; Yutong Huang; Tao Wang; Qian Li; Tingting Luo; Weilin Liu. "Ultrasound assisted glycation decreased the potential allergenicity through changing epitope and structures of Ses i 3." Food research international (Ottawa, Ont.) (2025).

Epitope: Ses i 3 S-5
Chemical type: Peptide from protein
Sequence: FFKGPRQQQQGR
Position: 571-582
Source molecule (GenBank): NP_001291343.1
Assay category: BCell
Result: Positive
Host:  27-50 years

Epitope: Ses i 3 S-5
Chemical type: Peptide from protein
Sequence: FFKGPRQQQQGR
Position: 571-582
Source molecule (GenBank): NP_001291343.1
Assay category: BCell
Result: Positive
Host:  27-50 years

Epitope: Ses i 3 S-2
Chemical type: Peptide from protein
Sequence: RRCQEEYQREKGRQ
Position: 109-122
Source molecule (GenBank): NP_001291343.1
Assay category: BCell
Result: Negative
Host:  27-50 years

Epitope: Ses i 3 S-3
Chemical type: Peptide from protein
Sequence: EREEEQEEQGRGRIP
Position: 181-195
Source molecule (GenBank): NP_001291343.1
Assay category: BCell
Result: Negative
Host:  27-50 years

Epitope: Ses i 3 S-4
Chemical type: Peptide from protein
Sequence: CPHMSRSRGSYQG
Position: 465-477
Source molecule (GenBank): NP_001291343.1
Assay category: BCell
Result: Negative
Host:  27-50 years
Reference: Wei Hu; Fen Xie; Yong Wu; Xuanyi Meng; Anshu Yang; Zhihua Wu; Jinyan Gao; Xin Li; Hongbing Chen. "Identification and Validation of Key Amino Acids in IgE Linear Epitopes of β-Lactoglobulin: Comparison of Recognition Patterns of Chinese Bovine Milk-Allergic Sera with Different Symptoms." Journal of agricultural and food chemistry (2025).

Epitope: β-lactoglobulin 89-103
Chemical type: Peptide from protein
Sequence: ENKVLVLDTDYKKYL
Position: 105-119
Source molecule (GenBank): P02754.3
Assay category: BCell
Result: Positive
Host:  0-20 years
Reference: Chunhua Shi; Ze Tian; Jun Yan; Mao Zhang; Pariya Sukhumalchandra; Edward Chang; Guojun Yang; Junping You; Meng Cui; Qing Shi; Celine Kerros; Anne Philips; Na Qiao; Hiroki Torikai; Sathvik Patchametla; Anna Sergeeva; Lisa St John; Helen He; Dmitri Wiederschain; Benjamin H Lee; Geraldine L C Paulus; Dongxing Zha; Jeffrey Molldrem; Gheath Alatrash. "Immunotherapy targeting a leader sequence cathepsin G-derived peptide." Leukemia (2025).

Epitope: CG1
Chemical type: Peptide from protein
Sequence: FLLPTGAEA
Position: 10-18
Source molecule (GenBank): P08311.2
Assay category: MhcLigandElution
Result: Negative

Epitope: CG1
Chemical type: Peptide from protein
Sequence: FLLPTGAEA
Position: 10-18
Source molecule (GenBank): P08311.2
Assay category: MhcLigandElution
Result: Negative

Epitope: CG1
Chemical type: Peptide from protein
Sequence: FLLPTGAEA
Position: 10-18
Source molecule (GenBank): P08311.2
Assay category: MhcLigandElution
Result: Positive

Epitope: CG1
Chemical type: Peptide from protein
Sequence: FLLPTGAEA
Position: 10-18
Source molecule (GenBank): P08311.2
Assay category: MhcLigandElution
Result: Positive

Epitope: CG1
Chemical type: Peptide from protein
Sequence: FLLPTGAEA
Position: 10-18
Source molecule (GenBank): P08311.2
Assay category: MhcLigandElution
Result: Negative

Epitope: CG1
Chemical type: Peptide from protein
Sequence: FLLPTGAEA
Position: 10-18
Source molecule (GenBank): P08311.2
Assay category: MhcLigandElution
Result: Negative

Epitope: CG1
Chemical type: Peptide from protein
Sequence: FLLPTGAEA
Position: 10-18
Source molecule (GenBank): P08311.2
Assay category: MhcLigandElution
Result: Negative

Epitope: CG1
Chemical type: Peptide from protein
Sequence: FLLPTGAEA
Position: 10-18
Source molecule (GenBank): P08311.2
Assay category: MhcLigandElution
Result: Negative
Reference: Ying Jia; Ariane Garcia; Elizabeth Reyes. "Single-Chain Variable Fragments: Targeting Snake Venom Phospholipase A<sub>2</sub> and Serine Protease." Toxins (2025).

Epitope: Lys49
Chemical type: Peptide, no natural source
Sequence: YNKKYILKFFSKK
Assay category: BCell
Result: Positive

Epitope: Asp49
Chemical type: Peptide, no natural source
Sequence: NLLQFNKMIKEETGK
Assay category: BCell
Result: Positive

Epitope: SP
Chemical type: Peptide, no natural source
Sequence: LQGGKDTSHYDSGGP
Assay category: BCell
Result: Positive
Reference: Yu Cheng Chua; Sarah L Draper; Shirley Le; Maria N de Menezes; Mitch Ganley; Zhengyu Ge; Ariane Lee; Taylah Phabmixay; Daria Hirschmann; Sage A Robinson; Peck Szee Tan; Kirsteen M Tullett; Regan J Anderson; Dhilshan Jayasinghe; Anton Cozijnsen; Mireille H Lahoud; Irina Caminschi; Lynette Beattie; Geoffrey I McFadden; David S Larsen; Tsuneyasu Kaisho; Stephanie Gras; Ian F Hermans; Benjamin J Compton; William R Heath; Gavin F Painter; Lauren E Holz. "Mechanistic insight into the induction of liver tissue-resident memory CD8<sup>+</sup> T cells by glycolipid-peptide vaccination." Cell reports (2025).

Epitope: RPL6
Chemical type: Peptide from protein
Sequence: NVFDFNNL
Position: 120-127
Source molecule (GenBank): XP_034423676.1
Assay category: TCell
Result: Positive
Host: F 6-12 weeks
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: RPL6
Chemical type: Peptide from protein
Sequence: NVFDFNNL
Position: 120-127
Source molecule (GenBank): XP_034423676.1
Assay category: TCell
Result: Positive
Host: F 6-12 weeks
Reference: Luis Gabriel González-Lodeiro; Patricia Barrios Roque; Nivaldo Gómez Hernández; Danya Medina-Carrasco; Lisandra E García de Castro; Vivian Huerta Galindo. "Differential Serotype Specificity in the IgG Subclass Profile of the Anti-Domain III Response Elicited by Dengue Virus Infection." Journal of medical virology (2025).

Epitope: DVIII E IgG2
Chemical type: Discontinuous protein residues
Discontinuous residues: L308, E311, E314, L321, D330, T353, G374
Source molecule (GenBank): AAN32775.1
Assay category: BCell
Result: Positive

Epitope: DVIII E IgG3
Chemical type: Discontinuous protein residues
Discontinuous residues: D290, K291, M297, G304, L308, K310, E314, E327, D330, R350, T353, I357, V365, E368, G374
Source molecule (GenBank): AUA17943.1
Assay category: BCell
Result: Positive

Epitope: DVIII E IgG4
Chemical type: Discontinuous protein residues
Discontinuous residues: L308, Q316, E327
Source molecule (GenBank): AAN32775.1
Assay category: BCell
Result: Positive

Epitope: DVIII E IgG1 primary
Chemical type: Discontinuous protein residues
Discontinuous residues: D290, K291, G304, K307, K325, E327, D330, P332, D360, K361, E362, V379, G383, E384, K385, L387, K388
Source molecule (GenBank): AAN32775.1
Assay category: BCell
Result: Positive

Epitope: DVIII E IgG4 primary
Chemical type: Discontinuous protein residues
Discontinuous residues: L308, Q316, E327
Source molecule (GenBank): AAN32775.1
Assay category: BCell
Result: Positive
Reference: David J Vance; Grace Freeman-Gallant; Kathleen McCarthy; Carol Lyn Piazza; Yang Chen; Clint Vorauer; Beatrice Muriuki; Michael J Rudolph; Lisa Cavacini; Miklos Guttman; Nicholas J Mantis. "A type-specific B-cell epitope at the apex of outer surface protein C (OspC) of the Lyme disease spirochete, ." Microbiology spectrum (2025).

Epitope: Epitope of mAb 8C1 on B. burgdorferi OspC-A
Chemical type: Peptide from protein
Sequence: CSETFTNKLKEKHTDLGKEGV
Position: 130-150
Source molecule (GenBank): Q07337.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Epitope of mAb 8C1 on B. burgdorferi OspC-A
Chemical type: Peptide from protein
Sequence: CSETFTNKLKEKHTDLGKEGV
Position: 130-150
Source molecule (GenBank): Q07337.1
Assay category: BCell
Result: Positive
Quantitative measurement: 9.2
Host: F 10 weeks

Epitope: Epitope of mAb 8C1 on B. burgdorferi OspC-A
Chemical type: Peptide from protein
Sequence: CSETFTNKLKEKHTDLGKEGV
Position: 130-150
Source molecule (GenBank): Q07337.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Epitope of mAb 8C1 on B. burgdorferi OspC-A
Chemical type: Peptide from protein
Sequence: CSETFTNKLKEKHTDLGKEGV
Position: 130-150
Source molecule (GenBank): Q07337.1
Assay category: BCell
Result: Positive
Host: F 10 weeks

Epitope: Epitope of mAb 8C1 on B. burgdorferi OspC-A
Chemical type: Peptide from protein
Sequence: CSETFTNKLKEKHTDLGKEGV
Position: 130-150
Source molecule (GenBank): Q07337.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 8C1 on B. burgdorferi OspC-A
Chemical type: Peptide from protein
Sequence: CSETFTNKLKEKHTDLGKEGV
Position: 130-150
Source molecule (GenBank): Q07337.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.7
Host: F 10 weeks

Epitope: Epitope of mAb 8C1 on B. burgdorferi OspC-A
Chemical type: Peptide from protein
Sequence: CSETFTNKLKEKHTDLGKEGV
Position: 130-150
Source molecule (GenBank): Q07337.1
Assay category: BCell
Result: Positive
Host: F 10 weeks
Reference: Jun-Lun Meng; Zi-Xuan Dong; Yan-Ru Chen; Meng-Hsuan Lin; Yu-Ching Liu; Steve R Roffler; Wen-Wei Lin; Chin-Yuan Chang; Shey-Cherng Tzou; Tian-Lu Cheng; Hsiao-Chen Huang; Zhi-Qin Li; Yen-Cheng Lin; Yu-Cheng Su. "pH-Responsive Polyethylene Glycol Engagers for Enhanced Brain Delivery of PEGylated Nanomedicine to Treat Glioblastoma." ACS nano (2025).

Epitope: Epitope of Fab h6.3 on PEG
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 2.26

Epitope: Epitope of Fab h6.3 on PEG
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Reference: Huanyu Z Li; Ashley C W Pike; Yung-Ning Chang; Dheeraj Prakaash; Zuzana Gelova; Josefina Stanka; Christophe Moreau; Hannah C Scott; Frank Wunder; Gernot Wolf; Andreea Scacioc; Gavin McKinley; Helena Batoulis; Shubhashish Mukhopadhyay; Andrea Garofoli; Adán Pinto-Fernández; Benedikt M Kessler; Nicola A Burgess-Brown; Saša Štefanić; Tabea Wiedmer; Katharina L Dürr; Vera Puetter; Alexander Ehrmann; Syma Khalid; Alvaro Ingles-Prieto; Giulio Superti-Furga; David B Sauer. "Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2." Nature communications (2025).

Epitope: Epitope of nanobody D12 on SPNS2
Chemical type: Discontinuous protein residues
Discontinuous residues: R389, L390, T392, Q393, M448, Y449, V451, P453, R456, R530, A531, E534, Q535, V537, N538
Source molecule (GenBank): Q8IVW8.2
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody D12 on SPNS2
Chemical type: Discontinuous protein residues
Discontinuous residues: R389, L390, T392, Q393, M448, Y449, V451, P453, R456, R530, A531, E534, Q535, V537, N538
Source molecule (GenBank): Q8IVW8.2
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody D12 on SPNS2
Chemical type: Discontinuous protein residues
Discontinuous residues: R389, L390, T392, Q393, M448, Y449, V451, P453, R456, R530, A531, E534, Q535, V537, N538
Source molecule (GenBank): Q8IVW8.2
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody D12 on SPNS2
Chemical type: Discontinuous protein residues
Discontinuous residues: R389, L390, T392, Q393, M448, Y449, V451, P453, R456, R530, A531, E534, Q535, V537, N538
Source molecule (GenBank): Q8IVW8.2
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody D12 on SPNS2
Chemical type: Discontinuous protein residues
Discontinuous residues: R389, L390, T392, Q393, M448, Y449, V451, P453, R456, R530, A531, E534, Q535, V537, N538
Source molecule (GenBank): Q8IVW8.2
Assay category: BCell
Result: Positive
Quantitative measurement: 7.75

Epitope: Epitope of nanobody D12 on SPNS2
Chemical type: Discontinuous protein residues
Discontinuous residues: R389, L390, T392, Q393, M448, Y449, V451, P453, R456, R530, A531, E534, Q535, V537, N538
Source molecule (GenBank): Q8IVW8.2
Assay category: BCell
Result: Positive
Quantitative measurement: 146000.0

Epitope: Epitope of nanobody D12 on SPNS2
Chemical type: Discontinuous protein residues
Discontinuous residues: R389, L390, T392, Q393, M448, Y449, V451, P453, R456, R530, A531, E534, Q535, V537, N538
Source molecule (GenBank): Q8IVW8.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00109
Reference: Yongchan Lee; Chunhuan Jin; Ryuichi Ohgaki; Minhui Xu; Satoshi Ogasawara; Rangana Warshamanage; Keitaro Yamashita; Garib Murshudov; Osamu Nureki; Takeshi Murata; Yoshikatsu Kanai. "Structural basis of anticancer drug recognition and amino acid transport by LAT1." Nature communications (2025).

Epitope: Epitope of Fab170 on CD98 heavy chain
Chemical type: Discontinuous protein residues
Discontinuous residues: Q448, S545, A546, G547, P548, G549, G570, D571, V572, G573, L574, S575, A576, G577, Q579, S581, E612, R613, E617, P618
Source molecule (GenBank): P08195.3
Assay category: BCell
Result: Positive
Host: F 4 weeks

Epitope: Epitope of Fab170 on CD98 heavy chain
Chemical type: Discontinuous protein residues
Discontinuous residues: Q448, S545, A546, G547, P548, G549, G570, D571, V572, G573, L574, S575, A576, G577, Q579, S581, E612, R613, E617, P618
Source molecule (GenBank): P08195.3
Assay category: BCell
Result: Positive
Host: F 4 weeks

Epitope: Epitope of Fab170 on CD98 heavy chain
Chemical type: Discontinuous protein residues
Discontinuous residues: Q448, S545, A546, G547, P548, G549, G570, D571, V572, G573, L574, S575, A576, G577, Q579, S581, E612, R613, E617, P618
Source molecule (GenBank): P08195.3
Assay category: BCell
Result: Positive
Host: F 4 weeks
Reference: Juraj Velcicky; Gregor Cremosnik; Clemens Scheufler; Peter Meier; Emmanuelle Wirth; Richard Felber; Paul Ramage; Michael Schaefer; Christian Kaiser; Sylvie Lehmann; Raphaela Kutil; Sandra Singeisen; Dorothee Mueller-Ristig; Simone Popp; Regis Cebe; Philipp Lehr; Klemens Kaupmann; Paulus Erbel; Till A Röhn; Jerome Giovannoni; Christoph E Dumelin; Georg Martiny-Baron. "Discovery of selective low molecular weight interleukin-36 receptor antagonists by encoded library technologies." Nature communications (2025).

Epitope: Epitope of BI655130 (spesolimab) Fab on IL-36R
Chemical type: Discontinuous protein residues
Discontinuous residues: W87, E114, W117, C118, D119, T120, S121, I122, G123, G124, L125, P126, N127, L128, Y132, D164, C165, N166, R190, N192, G211, I212, T213
Source molecule (GenBank): Q9HB29.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2.3

Epitope: Epitope of BI655130 (spesolimab) Fab on IL-36R
Chemical type: Discontinuous protein residues
Discontinuous residues: W87, E114, W117, C118, D119, T120, S121, I122, G123, G124, L125, P126, N127, L128, Y132, D164, C165, N166, R190, N192, G211, I212, T213
Source molecule (GenBank): Q9HB29.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2.4

Epitope: Epitope of BI655130 (spesolimab) Fab on IL-36R
Chemical type: Discontinuous protein residues
Discontinuous residues: W87, E114, W117, C118, D119, T120, S121, I122, G123, G124, L125, P126, N127, L128, Y132, D164, C165, N166, R190, N192, G211, I212, T213
Source molecule (GenBank): Q9HB29.2
Assay category: BCell
Result: Positive