Reference: Luke N Robinson; Kannan Tharakaraman; Kirk J Rowley; Vivian V Costa; Kuan Rong Chan; Yee Hwa Wong; Li Ching Ong; Hwee Cheng Tan; Tyree Koch; David Cain; Rama Kirloskar; Karthik Viswanathan; Chong Wai Liew; Hamid Tissire; Boopathy Ramakrishnan; James R Myette; Gregory J Babcock; V Sasisekharan; Sylvie Alonso; Jianzhu Chen; Julien Lescar; Zachary Shriver; Eng Eong Ooi; Ram Sasisekharan. "Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope." Cell (2015).

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.0

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive
Quantitative measurement: 7.9

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 300.0

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.015

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.041

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.8

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.0

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.49

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive
Quantitative measurement: 118.5

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.27

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv513 on DENV4 E
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, G328, A329, T361, N362, V364, N366, S385, L387, T388, L389, H390, W391
Source molecule (GenBank): ABD17419.1
Assay category: BCell
Result: Positive