Reference: David R Martinez; Alexandra Schäfer; Sophie Gobeil; Dapeng Li; Gabriela De la Cruz; Robert Parks; Xiaozhi Lu; Maggie Barr; Victoria Stalls; Katarzyna Janowska; Esther Beaudoin; Kartik Manne; Katayoun Mansouri; Robert J Edwards; Kenneth Cronin; Boyd Yount; Kara Anasti; Stephanie A Montgomery; Juanjie Tang; Hana Golding; Shaunna Shen; Tongqing Zhou; Peter D Kwong; Barney S Graham; John R Mascola; David C Montefiori; S Munir Alam; Gregory Sempowski; Gregory D Sempowski; Surender Khurana; Kevin Wiehe; Kevin O Saunders; Priyamvada Acharya; Barton F Haynes; Ralph S Baric. "A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice." Science translational medicine (2022).

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.1

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.1

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive
Quantitative measurement: 86020.0

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000010

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive
Quantitative measurement: 96220.0

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000010

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DH1047 Fab on SARS-CoV-1 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T359, F361, S362, T363, F364, K365, C366, S370, A371, K390, D392, D393, V394, R395, Q396, Q401, T402, V404, I405, V420, N424, R426, T485, T486, G488, I489, G490, Q492
Source molecule (GenBank): P59594.1
Assay category: BCell
Result: Positive