Reference: Jeongmin Hwang; Tonatiuh A Ocampo; Vinzenz Mayer; Janice Kang; Krishna S Paranandi; Young Jun Kim; Zhenyu Han; John P Cavaliere; Sergej Kudruk; Jochen H Lorch; Chad A Mirkin. "E7<sub>11-19</sub> placement and orientation dictate CD8<sup>+</sup> T cell response in structurally defined spherical nucleic acid vaccines." Science advances (2026).

Epitope: HPV E7<sub>11-19</sub>
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV E7<sub>11-19</sub>
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E7<sub>11-19</sub>
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HPV E7<sub>11-19</sub>
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive

Epitope: HPV E7<sub>11-19</sub>
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HPV E7<sub>11-19</sub>
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV E7<sub>11-19</sub>
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive

Epitope: HPV E7<sub>11-19</sub>
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: MhcBinding
Result: Positive

Epitope: HPV C-E7<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: CYMLDLQPET
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV C-E7<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: CYMLDLQPET
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV C-E7<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: CYMLDLQPET
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HPV C-E7<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: CYMLDLQPET
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HPV C-E7<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: CYMLDLQPET
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HPV C-E7<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: CYMLDLQPET
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV C-E7<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: CYMLDLQPET
Assay category: TCell
Result: Positive

Epitope: HPV C-E7<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: CYMLDLQPET
Assay category: TCell
Result: Positive

Epitope: HPV C-E7<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: CYMLDLQPET
Assay category: MhcBinding
Result: Positive

Epitope: HPV E7-C<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: YMLDLQPETC
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E7-C<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: YMLDLQPETC
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HPV E7-C<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: YMLDLQPETC
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HPV E7-C<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: YMLDLQPETC
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV E7-C<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: YMLDLQPETC
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV E7-C<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: YMLDLQPETC
Assay category: TCell
Result: Positive

Epitope: HPV E7-C<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: YMLDLQPETC
Assay category: TCell
Result: Positive

Epitope: HPV E7-C<sub>11-19</sub>
Chemical type: Peptide, no natural source
Sequence: YMLDLQPETC
Assay category: MhcBinding
Result: Positive