Reference: Antoine Sacquin; Thomas Chaigneau; Valérie Defaweux; Micheline Adam; Benoit Schneider; Martine Bruley Rosset; Marc Eloit. "Prolongation of prion disease-associated symptomatic phase relates to CD3+ T cell recruitment into the CNS in murine scrapie-infected mice." Brain, behavior, and immunity (2012).

Epitope: PrP (103-111)
Chemical type: Peptide from protein
Sequence: KPKTNLKHV
Position: 103-111
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP (103-111)
Chemical type: Peptide from protein
Sequence: KPKTNLKHV
Position: 103-111
Source molecule (GenBank): P04925.2
Assay category: MhcBinding
Result: Positive-Low

Epitope: PrP (166-174)
Chemical type: Peptide from protein
Sequence: DQYSNQNNF
Position: 166-174
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP (166-174)
Chemical type: Peptide from protein
Sequence: DQYSNQNNF
Position: 166-174
Source molecule (GenBank): P04925.2
Assay category: MhcBinding
Result: Positive-Low

Epitope: PrP (168-176)
Chemical type: Peptide from protein
Sequence: YSNQNNFVH
Position: 168-176
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP (168-176)
Chemical type: Peptide from protein
Sequence: YSNQNNFVH
Position: 168-176
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP (168-176)
Chemical type: Peptide from protein
Sequence: YSNQNNFVH
Position: 168-176
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Negative

Epitope: PrP (168-176)
Chemical type: Peptide from protein
Sequence: YSNQNNFVH
Position: 168-176
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: PrP (168-176)
Chemical type: Peptide from protein
Sequence: YSNQNNFVH
Position: 168-176
Source molecule (GenBank): P04925.2
Assay category: MhcBinding
Result: Positive-Low

Epitope: PrP (192-200)
Chemical type: Peptide from protein
Sequence: TKGENFTET
Position: 192-200
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP (192-200)
Chemical type: Peptide from protein
Sequence: TKGENFTET
Position: 192-200
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: PrP (192-200)
Chemical type: Peptide from protein
Sequence: TKGENFTET
Position: 192-200
Source molecule (GenBank): P04925.2
Assay category: MhcBinding
Result: Positive-Low

Epitope: PrP (217-225)
Chemical type: Peptide from protein
Sequence: YQRESQAYY
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP (217-225)
Chemical type: Peptide from protein
Sequence: YQRESQAYY
Assay category: TCell
Result: Negative

Epitope: PrP (217-225)
Chemical type: Peptide from protein
Sequence: YQRESQAYY
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: PrP (217-225)
Chemical type: Peptide from protein
Sequence: YQRESQAYY
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP (217-225)
Chemical type: Peptide from protein
Sequence: YQRESQAYY
Assay category: MhcBinding
Result: Positive-Low

Epitope: 103NP
Chemical type: Peptide, no natural source
Sequence: ASNTNLKHM
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 103NP
Chemical type: Peptide, no natural source
Sequence: ASNTNLKHM
Assay category: MhcBinding
Result: Positive

Epitope: 166NP
Chemical type: Peptide, no natural source
Sequence: ASNSNQNNM
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 166NP
Chemical type: Peptide, no natural source
Sequence: ASNSNQNNM
Assay category: MhcBinding
Result: Positive

Epitope: 192NP
Chemical type: Peptide, no natural source
Sequence: ASNENFTEM
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 192NP
Chemical type: Peptide, no natural source
Sequence: ASNENFTEM
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 192NP
Chemical type: Peptide, no natural source
Sequence: ASNENFTEM
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 192NP
Chemical type: Peptide, no natural source
Sequence: ASNENFTEM
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: 192NP
Chemical type: Peptide, no natural source
Sequence: ASNENFTEM
Assay category: TCell
Result: Positive
Quantitative measurement: 6.0

Epitope: 192NP
Chemical type: Peptide, no natural source
Sequence: ASNENFTEM
Assay category: MhcBinding
Result: Positive

Epitope: 217NP
Chemical type: Peptide, no natural source
Sequence: ASNENQAY
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 217NP
Chemical type: Peptide, no natural source
Sequence: ASNENQAY
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 217NP
Chemical type: Peptide, no natural source
Sequence: ASNENQAY
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 217NP
Chemical type: Peptide, no natural source
Sequence: ASNENQAY
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: 217NP
Chemical type: Peptide, no natural source
Sequence: ASNENQAY
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 217NP
Chemical type: Peptide, no natural source
Sequence: ASNENQAY
Assay category: TCell
Result: Positive

Epitope: 217NP
Chemical type: Peptide, no natural source
Sequence: ASNENQAY
Assay category: TCell
Result: Positive-High
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 217NP
Chemical type: Peptide, no natural source
Sequence: ASNENQAY
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 217NP
Chemical type: Peptide, no natural source
Sequence: ASNENQAY
Assay category: TCell
Result: Positive

Epitope: 217NP
Chemical type: Peptide, no natural source
Sequence: ASNENQAY
Assay category: MhcBinding
Result: Positive