Reference: Dongping Zhao; Liqin Liu; Xinlin Liu; Jinlei Zhang; Yuqing Yin; Linli Luan; Dingwen Jiang; Xiong Yang; Lei Li; Hualong Xiong; Dongming Xing; Qingbing Zheng; Ningshao Xia; Yuyong Tao; Shaowei Li; Haiming Huang. "A potent synthetic nanobody with broad-spectrum activity neutralizes SARS-CoV-2 virus and the Omicron variant BA.1 through a unique binding mode." Journal of nanobiotechnology (2022).

Epitope: Epitope of Nb C5G2 on SARS CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q115, N165, T167, I231, G232, R346, A348, S349, Y351, A352, W353, N354, R355, K356, Y449, N450, L452, R466, I468, T470, E471, I472, G482, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb C5G2 on SARS CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q115, N165, T167, I231, G232, R346, A348, S349, Y351, A352, W353, N354, R355, K356, Y449, N450, L452, R466, I468, T470, E471, I472, G482, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb C5G2 on SARS CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q115, N165, T167, I231, G232, R346, A348, S349, Y351, A352, W353, N354, R355, K356, Y449, N450, L452, R466, I468, T470, E471, I472, G482, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb C5G2 on SARS CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q115, N165, T167, I231, G232, R346, A348, S349, Y351, A352, W353, N354, R355, K356, Y449, N450, L452, R466, I468, T470, E471, I472, G482, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb C5G2 on SARS CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q115, N165, T167, I231, G232, R346, A348, S349, Y351, A352, W353, N354, R355, K356, Y449, N450, L452, R466, I468, T470, E471, I472, G482, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb C5G2 on SARS CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q115, N165, T167, I231, G232, R346, A348, S349, Y351, A352, W353, N354, R355, K356, Y449, N450, L452, R466, I468, T470, E471, I472, G482, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb C5G2 on SARS CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q115, N165, T167, I231, G232, R346, A348, S349, Y351, A352, W353, N354, R355, K356, Y449, N450, L452, R466, I468, T470, E471, I472, G482, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 17600.0

Epitope: Epitope of Nb C5G2 on SARS CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q115, N165, T167, I231, G232, R346, A348, S349, Y351, A352, W353, N354, R355, K356, Y449, N450, L452, R466, I468, T470, E471, I472, G482, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb C5G2 on SARS CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q115, N165, T167, I231, G232, R346, A348, S349, Y351, A352, W353, N354, R355, K356, Y449, N450, L452, R466, I468, T470, E471, I472, G482, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.62

Epitope: Epitope of Nb C5G2 on SARS CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q115, N165, T167, I231, G232, R346, A348, S349, Y351, A352, W353, N354, R355, K356, Y449, N450, L452, R466, I468, T470, E471, I472, G482, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000284

Epitope: Epitope of mNb6 on SARS-CoV2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R403, K417, G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, Q493, S494, Y495, G496, Q498, Y505; C: A372, S373, F374, N439, N440, P499, T500, V503
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mNb6 on SARS-CoV2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R403, K417, G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, Q493, S494, Y495, G496, Q498, Y505; C: A372, S373, F374, N439, N440, P499, T500, V503
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 16300.0

Epitope: Epitope of mNb6 on SARS-CoV2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R403, K417, G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, Q493, S494, Y495, G496, Q498, Y505; C: A372, S373, F374, N439, N440, P499, T500, V503
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mNb6 on SARS-CoV2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R403, K417, G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, Q493, S494, Y495, G496, Q498, Y505; C: A372, S373, F374, N439, N440, P499, T500, V503
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mNb6 on SARS-CoV2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R403, K417, G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, Q493, S494, Y495, G496, Q498, Y505; C: A372, S373, F374, N439, N440, P499, T500, V503
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mNb6 on SARS-CoV2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R403, K417, G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, Q493, S494, Y495, G496, Q498, Y505; C: A372, S373, F374, N439, N440, P499, T500, V503
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.48

Epitope: Epitope of mNb6 on SARS-CoV2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R403, K417, G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, Q493, S494, Y495, G496, Q498, Y505; C: A372, S373, F374, N439, N440, P499, T500, V503
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000566