Reference: Jane Marttila; Suvi Huttunen; Outi Vaarala; Kunimasa Suzuki; John F Elliott; Ale Närvänen; Mikael Knip; Olli Simell; Jorma Ilonen. "T-cell reactivity to insulin peptide A1-12 in children with recently diagnosed type 1 diabetes or multiple beta-cell autoantibodies." Journal of autoimmunity (2008).

Epitope: B1
Chemical type: Peptide from protein
Sequence: GIVEQCCASVCS
Position: 1-12
Source molecule (GenBank): 550085A
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  2-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B1
Chemical type: Peptide from protein
Sequence: GIVEQCCASVCS
Position: 1-12
Source molecule (GenBank): 550085A
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B1
Chemical type: Peptide from protein
Sequence: GIVEQCCASVCS
Position: 1-12
Source molecule (GenBank): 550085A
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  2-15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H1
Chemical type: Peptide from protein
Sequence: GIVEQCCTSICS
Position: 1-12
Source molecule (GenBank): 1ZNJ_A
Assay category: TCell
Result: Positive
Host:  2-15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H1
Chemical type: Peptide from protein
Sequence: GIVEQCCTSICS
Position: 1-12
Source molecule (GenBank): 1ZNJ_A
Assay category: TCell
Result: Positive
Host:  2-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H1
Chemical type: Peptide from protein
Sequence: GIVEQCCTSICS
Position: 1-12
Source molecule (GenBank): 1ZNJ_A
Assay category: TCell
Result: Positive
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H1
Chemical type: Peptide from protein
Sequence: GIVEQCCTSICS
Position: 1-12
Source molecule (GenBank): 1ZNJ_A
Assay category: TCell
Result: Positive
Host:  2-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H1
Chemical type: Peptide from protein
Sequence: GIVEQCCTSICS
Position: 1-12
Source molecule (GenBank): 1ZNJ_A
Assay category: TCell
Result: Positive
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H1
Chemical type: Peptide from protein
Sequence: GIVEQCCTSICS
Position: 1-12
Source molecule (GenBank): 1ZNJ_A
Assay category: TCell
Result: Positive
Host:  2-15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B2
Chemical type: Peptide from protein
Sequence: QCCASVCSLYQL
Position: 5-16
Source molecule (GenBank): 550085A
Assay category: TCell
Result: Negative
MHC allele types: 340 341
Host:  2-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B2
Chemical type: Peptide from protein
Sequence: QCCASVCSLYQL
Position: 5-16
Source molecule (GenBank): 550085A
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  2-15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B2
Chemical type: Peptide from protein
Sequence: QCCASVCSLYQL
Position: 5-16
Source molecule (GenBank): 550085A
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H2
Chemical type: Peptide from protein
Sequence: QCCTSICSLYQL
Position: 5-16
Source molecule (GenBank): 1ZNJ_A
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  2-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H2
Chemical type: Peptide from protein
Sequence: QCCTSICSLYQL
Position: 5-16
Source molecule (GenBank): 1ZNJ_A
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H2
Chemical type: Peptide from protein
Sequence: QCCTSICSLYQL
Position: 5-16
Source molecule (GenBank): 1ZNJ_A
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  2-15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B3
Chemical type: Peptide from protein
Sequence: SVCSLYQLENYCN
Position: 9-21
Source molecule (GenBank): 550085A
Assay category: TCell
Result: Negative
MHC allele types: 340 341
Host:  2-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B3
Chemical type: Peptide from protein
Sequence: SVCSLYQLENYCN
Position: 9-21
Source molecule (GenBank): 550085A
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B3
Chemical type: Peptide from protein
Sequence: SVCSLYQLENYCN
Position: 9-21
Source molecule (GenBank): 550085A
Assay category: TCell
Result: Negative
MHC allele types: 340 341
Host:  2-15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H3
Chemical type: Peptide from protein
Sequence: SICSLYQLENYCN
Position: 9-21
Source molecule (GenBank): 1ZNJ_A
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  2-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H3
Chemical type: Peptide from protein
Sequence: SICSLYQLENYCN
Position: 9-21
Source molecule (GenBank): 1ZNJ_A
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H3
Chemical type: Peptide from protein
Sequence: SICSLYQLENYCN
Position: 9-21
Source molecule (GenBank): 1ZNJ_A
Assay category: TCell
Result: Negative
MHC allele types: 340 341
Host:  2-15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B8
Chemical type: Peptide from protein
Sequence: VCGERGFFYTPKA
Position: 18-30
Source molecule (GenBank): 1APH_B
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B8
Chemical type: Peptide from protein
Sequence: VCGERGFFYTPKA
Position: 18-30
Source molecule (GenBank): 1APH_B
Assay category: TCell
Result: Negative
MHC allele types: 340 341
Host:  2-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B8
Chemical type: Peptide from protein
Sequence: VCGERGFFYTPKA
Position: 18-30
Source molecule (GenBank): 1APH_B
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  2-15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H8
Chemical type: Peptide from protein
Sequence: VCGERGFFYTPKT
Position: 18-30
Source molecule (GenBank): 1ZNJ_B
Assay category: TCell
Result: Negative
MHC allele types: 340 341
Host:  2-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H8
Chemical type: Peptide from protein
Sequence: VCGERGFFYTPKT
Position: 18-30
Source molecule (GenBank): 1ZNJ_B
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: H8
Chemical type: Peptide from protein
Sequence: VCGERGFFYTPKT
Position: 18-30
Source molecule (GenBank): 1ZNJ_B
Assay category: TCell
Result: Negative
MHC allele types: 340 341
Host:  2-15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 9-23
Source molecule (GenBank): 1XDA_B
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  2-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 9-23
Source molecule (GenBank): 1XDA_B
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 9-23
Source molecule (GenBank): 1XDA_B
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  2-15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IP-12
Chemical type: Peptide from protein
Sequence: GIVEQCCASVCSLYQ
Position: 1-15
Source molecule (GenBank): 550085A
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IP-12
Chemical type: Peptide from protein
Sequence: GIVEQCCASVCSLYQ
Position: 1-15
Source molecule (GenBank): 550085A
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  2-15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IP-12
Chemical type: Peptide from protein
Sequence: GIVEQCCASVCSLYQ
Position: 1-15
Source molecule (GenBank): 550085A
Assay category: TCell
Result: Positive
MHC allele types: 340 341
Host:  2-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo