Reference: Elisa K McCarthy; Amanda Vakos; Merylin Cottagiri; Joel J Mantilla; Lakshmi Santhanam; David L Thomas; L Mario Amzel; Noel R Rose; Dolores B Njoku. "Identification of a Shared Cytochrome p4502E1 Epitope Found in Anesthetic Drug-Induced and Viral Hepatitis." mSphere (2018).

Epitope: JHDN1
Chemical type: Peptide from protein
Sequence: SALGVTVALLVWAAFLLL
Position: 2-19
Source molecule (GenBank): P05181.1
Assay category: BCell
Result: Positive-Low
Host: F 8-10 weeks

Epitope: JHDN1
Chemical type: Peptide from protein
Sequence: SALGVTVALLVWAAFLLL
Position: 2-19
Source molecule (GenBank): P05181.1
Assay category: BCell
Result: Negative

Epitope: JHDN1
Chemical type: Peptide from protein
Sequence: SALGVTVALLVWAAFLLL
Position: 2-19
Source molecule (GenBank): P05181.1
Assay category: TCell
Result: Negative
Host: F 8-10 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: JHDN1
Chemical type: Peptide from protein
Sequence: SALGVTVALLVWAAFLLL
Position: 2-19
Source molecule (GenBank): P05181.1
Assay category: MhcBinding
Result: Positive

Epitope: JHDN2
Chemical type: Peptide from protein
Sequence: QRMVVMHGYKAVKEALLD
Position: 75-92
Source molecule (GenBank): P05181.1
Assay category: BCell
Result: Negative

Epitope: JHDN2
Chemical type: Peptide from protein
Sequence: QRMVVMHGYKAVKEALLD
Position: 75-92
Source molecule (GenBank): P05181.1
Assay category: MhcBinding
Result: Positive

Epitope: JHDN3
Chemical type: Peptide from protein
Sequence: HYLPGSHRKVIKNVAEVK
Position: 226-243
Source molecule (GenBank): P05181.1
Assay category: MhcBinding
Result: Negative

Epitope: JHDN4
Chemical type: Peptide from protein
Sequence: IFRGYLIPKGTVVVPTLDS
Position: 377-395
Source molecule (GenBank): P05181.1
Assay category: BCell
Result: Negative

Epitope: JHDN4
Chemical type: Peptide from protein
Sequence: IFRGYLIPKGTVVVPTLDS
Position: 377-395
Source molecule (GenBank): P05181.1
Assay category: MhcBinding
Result: Positive

Epitope: JHDN5
Chemical type: Peptide from protein
Sequence: GIIFNNGPTWKDIRRFSLTTL
Position: 113-133
Source molecule (GenBank): P05181.1
Assay category: BCell
Result: Positive-Low
Host: F 8-10 weeks

Epitope: JHDN5
Chemical type: Peptide from protein
Sequence: GIIFNNGPTWKDIRRFSLTTL
Position: 113-133
Source molecule (GenBank): P05181.1
Assay category: BCell
Result: Positive
Host: F 8-10 weeks

Epitope: JHDN5
Chemical type: Peptide from protein
Sequence: GIIFNNGPTWKDIRRFSLTTL
Position: 113-133
Source molecule (GenBank): P05181.1
Assay category: BCell
Result: Positive
Host:  mean: 52 years

Epitope: JHDN5
Chemical type: Peptide from protein
Sequence: GIIFNNGPTWKDIRRFSLTTL
Position: 113-133
Source molecule (GenBank): P05181.1
Assay category: BCell
Result: Positive

Epitope: JHDN5
Chemical type: Peptide from protein
Sequence: GIIFNNGPTWKDIRRFSLTTL
Position: 113-133
Source molecule (GenBank): P05181.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: JHDN5
Chemical type: Peptide from protein
Sequence: GIIFNNGPTWKDIRRFSLTTL
Position: 113-133
Source molecule (GenBank): P05181.1
Assay category: MhcBinding
Result: Negative

Epitope: JHDN6
Chemical type: Peptide from protein
Sequence: FNNGPTWKDIRRFSLTTLRN
Position: 116-135
Source molecule (GenBank): P05181.1
Assay category: BCell
Result: Negative

Epitope: JHDN6
Chemical type: Peptide from protein
Sequence: FNNGPTWKDIRRFSLTTLRN
Position: 116-135
Source molecule (GenBank): P05181.1
Assay category: MhcBinding
Result: Negative

Epitope: JHDN7
Chemical type: Peptide from protein
Sequence: GPTWKDIRRFSLTTLRNYGM
Position: 119-138
Source molecule (GenBank): P05181.1
Assay category: MhcBinding
Result: Negative

Epitope: JHDN8
Chemical type: Peptide from protein
Sequence: WKDIRRFSLTTLRNYGMGK
Position: 122-140
Source molecule (GenBank): P05181.1
Assay category: MhcBinding
Result: Negative

Epitope: JHDN9
Chemical type: Peptide from protein
Sequence: IRRFSLTTLRNYGMGKQGNES
Position: 125-145
Source molecule (GenBank): P05181.1
Assay category: BCell
Result: Negative

Epitope: JHDN9
Chemical type: Peptide from protein
Sequence: IRRFSLTTLRNYGMGKQGNES
Position: 125-145
Source molecule (GenBank): P05181.1
Assay category: MhcBinding
Result: Positive

Epitope: JHDN5 + TFA
Chemical type: Peptide from protein
Sequence: GIIFNNGPTWKDIRRFSLTTL
Position: 113-133
Source molecule (GenBank): P05181.1
Assay category: BCell
Result: Positive
Host: F 8-10 weeks

Epitope: JHDN5 + TFA
Chemical type: Peptide from protein
Sequence: GIIFNNGPTWKDIRRFSLTTL
Position: 113-133
Source molecule (GenBank): P05181.1
Assay category: BCell
Result: Positive
Host: F 8-10 weeks