Reference: Zehua Sun; Xiaojie Chu; Cynthia Adams; Tatiana V Ilina; Michel Guerrero; Guowu Lin; Chuan Chen; Dontcho Jelev; Rieko Ishima; Wei Li; John W Mellors; Guillermo Calero; Dimiter S Dimitrov. "Preclinical assessment of a novel human antibody VH domain targeting mesothelin as an antibody-drug conjugate." Molecular therapy oncolytics (2023).

Epitope: Epitope of VH 3C9 on Mesothelin
Chemical type: Discontinuous protein residues
Discontinuous residues: I311, D312, E313, D337, R338, N340, A341, P343, F344, Y346, E347, L349, D350, Y374, L377, K378, E400, V401, K403, E406
Source molecule (GenBank): Q13421.2
Assay category: BCell
Result: Positive

Epitope: Epitope of VH 3C9 on Mesothelin
Chemical type: Discontinuous protein residues
Discontinuous residues: I311, D312, E313, D337, R338, N340, A341, P343, F344, Y346, E347, L349, D350, Y374, L377, K378, E400, V401, K403, E406
Source molecule (GenBank): Q13421.2
Assay category: BCell
Result: Positive

Epitope: Epitope of VH 3C9 on Mesothelin
Chemical type: Discontinuous protein residues
Discontinuous residues: I311, D312, E313, D337, R338, N340, A341, P343, F344, Y346, E347, L349, D350, Y374, L377, K378, E400, V401, K403, E406
Source molecule (GenBank): Q13421.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2.9

Epitope: Epitope of VH 3C9 on Mesothelin
Chemical type: Discontinuous protein residues
Discontinuous residues: I311, D312, E313, D337, R338, N340, A341, P343, F344, Y346, E347, L349, D350, Y374, L377, K378, E400, V401, K403, E406
Source molecule (GenBank): Q13421.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2.6

Epitope: Epitope of VH 3C9 on Mesothelin
Chemical type: Discontinuous protein residues
Discontinuous residues: I311, D312, E313, D337, R338, N340, A341, P343, F344, Y346, E347, L349, D350, Y374, L377, K378, E400, V401, K403, E406
Source molecule (GenBank): Q13421.2
Assay category: BCell
Result: Positive
Quantitative measurement: 840000.0

Epitope: Epitope of VH 3C9 on Mesothelin
Chemical type: Discontinuous protein residues
Discontinuous residues: I311, D312, E313, D337, R338, N340, A341, P343, F344, Y346, E347, L349, D350, Y374, L377, K378, E400, V401, K403, E406
Source molecule (GenBank): Q13421.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0022

Epitope: Epitope of VH 3C9 on Mesothelin
Chemical type: Discontinuous protein residues
Discontinuous residues: I311, D312, E313, D337, R338, N340, A341, P343, F344, Y346, E347, L349, D350, Y374, L377, K378, E400, V401, K403, E406
Source molecule (GenBank): Q13421.2
Assay category: BCell
Result: Positive

Epitope: Epitope of VH 3C9 on Mesothelin
Chemical type: Discontinuous protein residues
Discontinuous residues: I311, D312, E313, D337, R338, N340, A341, P343, F344, Y346, E347, L349, D350, Y374, L377, K378, E400, V401, K403, E406
Source molecule (GenBank): Q13421.2
Assay category: BCell
Result: Positive

Epitope: Epitope of VH 3C9 on Mesothelin
Chemical type: Discontinuous protein residues
Discontinuous residues: I311, D312, E313, D337, R338, N340, A341, P343, F344, Y346, E347, L349, D350, Y374, L377, K378, E400, V401, K403, E406
Source molecule (GenBank): Q13421.2
Assay category: BCell
Result: Positive

Epitope: Epitope of VH 3C9 on Mesothelin
Chemical type: Discontinuous protein residues
Discontinuous residues: I311, D312, E313, D337, R338, N340, A341, P343, F344, Y346, E347, L349, D350, Y374, L377, K378, E400, V401, K403, E406
Source molecule (GenBank): Q13421.2
Assay category: BCell
Result: Positive-Low