Reference: Linan Wang; Masahiro Matsumoto; Yasushi Akahori; Naohiro Seo; Kazuko Shirakura; Takuma Kato; Yoichi Katsumoto; Yoshihiro Miyahara; Hiroshi Shiku. "Preclinical evaluation of a novel CAR-T therapy utilizing a scFv antibody highly specific to MAGE-A4<sub>p230-239</sub>/HLA-A∗02:01 complex." Molecular therapy : the journal of the American Society of Gene Therapy (2024).

Epitope: MAGE-A4  p230-239
Chemical type: Peptide from protein
Sequence: GVYDGREHTV
Position: 230-239
Source molecule (GenBank): P43358.2
Assay category: BCell
Result: Positive
Quantitative measurement: 22.0

Epitope: MAGE-A4  p230-239
Chemical type: Peptide from protein
Sequence: GVYDGREHTV
Position: 230-239
Source molecule (GenBank): P43358.2
Assay category: MhcBinding
Result: Positive

Epitope: G1A
Chemical type: Peptide, no natural source
Sequence: AVYDGREHTV
Assay category: MhcBinding
Result: Positive

Epitope: V2A
Chemical type: Peptide, no natural source
Sequence: GAYDGREHTV
Assay category: MhcBinding
Result: Positive

Epitope: Y3A
Chemical type: Peptide, no natural source
Sequence: GVADGREHTV
Assay category: MhcBinding
Result: Positive-Low

Epitope: D4A
Chemical type: Peptide, no natural source
Sequence: GVYAGREHTV
Assay category: MhcBinding
Result: Positive

Epitope: G5A
Chemical type: Peptide, no natural source
Sequence: GVYDAREHTV
Assay category: MhcBinding
Result: Positive-Low

Epitope: E7A
Chemical type: Peptide, no natural source
Sequence: GVYDGRAHTV
Assay category: MhcBinding
Result: Positive

Epitope: H8A
Chemical type: Peptide, no natural source
Sequence: GVYDGREATV
Assay category: MhcBinding
Result: Positive

Epitope: T9A
Chemical type: Peptide, no natural source
Sequence: GVYDGREHAV
Assay category: MhcBinding
Result: Positive

Epitope: V10A
Chemical type: Peptide, no natural source
Sequence: GVYDGREHTA
Assay category: MhcBinding
Result: Positive

Epitope: MAGE-A1
Chemical type: Peptide from protein
Sequence: EVYDGREHSA
Position: 222-231
Source molecule (GenBank): P43355.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: MAGE-A8
Chemical type: Peptide from protein
Sequence: GLYDGREHSV
Position: 232-241
Source molecule (GenBank): P43361.2
Assay category: MhcBinding
Result: Positive

Epitope: MAGE-A9
Chemical type: Peptide from protein
Sequence: GVYVGKEHMF
Position: 228-237
Source molecule (GenBank): P43362.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: MAGE-A10
Chemical type: Peptide from protein
Sequence: GLYDGREHLI
Assay category: MhcBinding
Result: Positive

Epitope: MAGE-A11
Chemical type: Peptide from protein
Sequence: GVYAGREHFL
Position: 342-351
Source molecule (GenBank): P43364.2
Assay category: MhcBinding
Result: Positive

Epitope: MAGE-B2
Chemical type: Peptide from protein
Sequence: GVYDGEEHSV
Position: 231-240
Source molecule (GenBank): O15479.3
Assay category: MhcBinding
Result: Positive

Epitope: MAGE-B10
Chemical type: Peptide from protein
Sequence: GLYDGIEHFM
Position: 231-240
Source molecule (GenBank): Q96LZ2.4
Assay category: MhcBinding
Result: Positive

Epitope: MAGE-C2
Chemical type: Peptide from protein
Sequence: GVYAGREHFV
Position: 257-266
Source molecule (GenBank): Q9UBF1.1
Assay category: MhcBinding
Result: Positive

Epitope: ADAMTS
Chemical type: Peptide from protein
Sequence: HVYNGRTHQW
Position: 123-132
Source molecule (GenBank): Q86TH1.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: Calcyphosin
Chemical type: Peptide from protein
Sequence: GVYSGRAHPK
Position: 206-215
Source molecule (GenBank): Q13938.2
Assay category: MhcBinding
Result: Positive-Low

Epitope: RISK1
Chemical type: Peptide from protein
Sequence: GVFDGRSRPR
Position: 464-473
Source molecule (GenBank): XP_016870087.1
Assay category: MhcBinding
Result: Positive

Epitope: RISK2
Chemical type: Peptide from protein
Sequence: GVFDGRSRP
Position: 464-472
Source molecule (GenBank): XP_016870087.1
Assay category: MhcBinding
Result: Positive

Epitope: RISK3
Chemical type: Peptide from protein
Sequence: GVFDGRSR
Position: 464-471
Source molecule (GenBank): XP_016870087.1
Assay category: MhcBinding
Result: Positive

Epitope: RISK4
Chemical type: Peptide from protein
Sequence: GIYMGRPTYG
Position: 205-214
Source molecule (GenBank): P62995.1
Assay category: MhcBinding
Result: Positive

Epitope: RISK5
Chemical type: Peptide from protein
Sequence: GIYMGRPTY
Position: 205-213
Source molecule (GenBank): P62995.1
Assay category: MhcBinding
Result: Positive

Epitope: RISK6-beta
Chemical type: Peptide from protein
Sequence: GIYMGRPT
Position: 205-212
Source molecule (GenBank): P62995.1
Assay category: MhcBinding
Result: Positive

Epitope: RISK8
Chemical type: Peptide from protein
Sequence: GIYMGRPTH
Position: 206-214
Source molecule (GenBank): Q13595.1
Assay category: MhcBinding
Result: Positive

Epitope: RISK6-alpha
Chemical type: Peptide from protein
Sequence: GIYMGRPT
Position: 206-213
Source molecule (GenBank): Q13595.1
Assay category: MhcBinding
Result: Positive

Epitope: RISK9
Chemical type: Peptide from protein
Sequence: GIFCYRRRRT
Position: 424-433
Source molecule (GenBank): Q9NQS3.1
Assay category: MhcBinding
Result: Positive

Epitope: RISK10
Chemical type: Peptide from protein
Sequence: GIFCYRRRR
Position: 424-432
Source molecule (GenBank): Q9NQS3.1
Assay category: MhcBinding
Result: Positive

Epitope: RISK11
Chemical type: Peptide from protein
Sequence: GIFCYRRR
Position: 424-431
Source molecule (GenBank): Q9NQS3.1
Assay category: MhcBinding
Result: Positive

Epitope: RISK12
Chemical type: Peptide from protein
Sequence: GVYCYRAAIG
Position: 730-739
Source molecule (GenBank): Q5H8A4.1
Assay category: MhcBinding
Result: Positive

Epitope: RISK13
Chemical type: Peptide from protein
Sequence: GVYCYRAAI
Position: 730-738
Source molecule (GenBank): Q5H8A4.1
Assay category: MhcBinding
Result: Positive

Epitope: RISK15
Chemical type: Peptide from protein
Sequence: GVYCYRAPGA
Position: 360-369
Source molecule (GenBank): Q86UW8.1
Assay category: MhcBinding
Result: Positive

Epitope: RISK16
Chemical type: Peptide from protein
Sequence: GVYCYRAPG
Position: 360-368
Source molecule (GenBank): Q86UW8.1
Assay category: MhcBinding
Result: Positive

Epitope: RISK17
Chemical type: Peptide from protein
Sequence: GVYCYRAP
Position: 360-367
Source molecule (GenBank): Q86UW8.1
Assay category: MhcBinding
Result: Positive

Epitope: MAGE-A4  p230-238
Chemical type: Peptide from protein
Sequence: GVYDGREHT
Position: 230-238
Source molecule (GenBank): P43358.2
Assay category: MhcBinding
Result: Positive

Epitope: MAGE-A4  p230-237
Chemical type: Peptide from protein
Sequence: GVYDGREH
Position: 230-237
Source molecule (GenBank): P43358.2
Assay category: MhcBinding
Result: Positive