Reference: M Oshima; J L Middlebrook; M Z Atassi. "Antibodies and T cells against synthetic peptides of the C-terminal domain (Hc) of botulinum neurotoxin type A and their cross-reaction with Hc." Immunology letters (1998).

Epitope: 3
Chemical type: Peptide from protein
Sequence: YESNHLIDLSRYASKINIG
Position: 883-901
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 3
Chemical type: Peptide from protein
Sequence: YESNHLIDLSRYASKINIG
Position: 883-901
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 3
Chemical type: Peptide from protein
Sequence: YESNHLIDLSRYASKINIG
Position: 883-901
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 3
Chemical type: Peptide from protein
Sequence: YESNHLIDLSRYASKINIG
Position: 883-901
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-8 weeks

Epitope: 3
Chemical type: Peptide from protein
Sequence: YESNHLIDLSRYASKINIG
Position: 883-901
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 3
Chemical type: Peptide from protein
Sequence: YESNHLIDLSRYASKINIG
Position: 883-901
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 3
Chemical type: Peptide from protein
Sequence: YESNHLIDLSRYASKINIG
Position: 883-901
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 3
Chemical type: Peptide from protein
Sequence: YESNHLIDLSRYASKINIG
Position: 883-901
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 4
Chemical type: Peptide from protein
Sequence: KINIGSKVNFDPIDKNQIQ
Position: 897-915
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 4
Chemical type: Peptide from protein
Sequence: KINIGSKVNFDPIDKNQIQ
Position: 897-915
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 4
Chemical type: Peptide from protein
Sequence: KINIGSKVNFDPIDKNQIQ
Position: 897-915
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 4
Chemical type: Peptide from protein
Sequence: KINIGSKVNFDPIDKNQIQ
Position: 897-915
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 5
Chemical type: Peptide from protein
Sequence: KNQIQLFNLESSKIEVILK
Position: 911-929
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 5
Chemical type: Peptide from protein
Sequence: KNQIQLFNLESSKIEVILK
Position: 911-929
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-8 weeks

Epitope: 5
Chemical type: Peptide from protein
Sequence: KNQIQLFNLESSKIEVILK
Position: 911-929
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 5
Chemical type: Peptide from protein
Sequence: KNQIQLFNLESSKIEVILK
Position: 911-929
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 6
Chemical type: Peptide from protein
Sequence: EVILKNAIVYNSMYENFST
Position: 925-943
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 6
Chemical type: Peptide from protein
Sequence: EVILKNAIVYNSMYENFST
Position: 925-943
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-8 weeks

Epitope: 6
Chemical type: Peptide from protein
Sequence: EVILKNAIVYNSMYENFST
Position: 925-943
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 6
Chemical type: Peptide from protein
Sequence: EVILKNAIVYNSMYENFST
Position: 925-943
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 7
Chemical type: Peptide from protein
Sequence: ENFSTSFWIRIPKYFNSIS
Position: 939-957
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 7
Chemical type: Peptide from protein
Sequence: ENFSTSFWIRIPKYFNSIS
Position: 939-957
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-8 weeks

Epitope: 7
Chemical type: Peptide from protein
Sequence: ENFSTSFWIRIPKYFNSIS
Position: 939-957
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 7
Chemical type: Peptide from protein
Sequence: ENFSTSFWIRIPKYFNSIS
Position: 939-957
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 7
Chemical type: Peptide from protein
Sequence: ENFSTSFWIRIPKYFNSIS
Position: 939-957
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 7
Chemical type: Peptide from protein
Sequence: ENFSTSFWIRIPKYFNSIS
Position: 939-957
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 7
Chemical type: Peptide from protein
Sequence: ENFSTSFWIRIPKYFNSIS
Position: 939-957
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 7
Chemical type: Peptide from protein
Sequence: ENFSTSFWIRIPKYFNSIS
Position: 939-957
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 9
Chemical type: Peptide from protein
Sequence: CMENNSGWKVSLNYGEIIW
Position: 967-985
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-8 weeks

Epitope: 9
Chemical type: Peptide from protein
Sequence: CMENNSGWKVSLNYGEIIW
Position: 967-985
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 9
Chemical type: Peptide from protein
Sequence: CMENNSGWKVSLNYGEIIW
Position: 967-985
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 9
Chemical type: Peptide from protein
Sequence: CMENNSGWKVSLNYGEIIW
Position: 967-985
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 10
Chemical type: Peptide from protein
Sequence: GEIIWTLQDTQEIKQRVVF
Position: 981-999
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 10
Chemical type: Peptide from protein
Sequence: GEIIWTLQDTQEIKQRVVF
Position: 981-999
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 10
Chemical type: Peptide from protein
Sequence: GEIIWTLQDTQEIKQRVVF
Position: 981-999
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 10
Chemical type: Peptide from protein
Sequence: GEIIWTLQDTQEIKQRVVF
Position: 981-999
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 10
Chemical type: Peptide from protein
Sequence: GEIIWTLQDTQEIKQRVVF
Position: 981-999
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 10
Chemical type: Peptide from protein
Sequence: GEIIWTLQDTQEIKQRVVF
Position: 981-999
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 10
Chemical type: Peptide from protein
Sequence: GEIIWTLQDTQEIKQRVVF
Position: 981-999
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 10
Chemical type: Peptide from protein
Sequence: GEIIWTLQDTQEIKQRVVF
Position: 981-999
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 11
Chemical type: Peptide from protein
Sequence: QRVVFKYSQMINISDYINR
Position: 995-1013
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-8 weeks

Epitope: 11
Chemical type: Peptide from protein
Sequence: QRVVFKYSQMINISDYINR
Position: 995-1013
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 11
Chemical type: Peptide from protein
Sequence: QRVVFKYSQMINISDYINR
Position: 995-1013
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 11
Chemical type: Peptide from protein
Sequence: QRVVFKYSQMINISDYINR
Position: 995-1013
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 12
Chemical type: Peptide from protein
Sequence: DYINRWIFVTITNNRLNNS
Position: 1009-1027
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 12
Chemical type: Peptide from protein
Sequence: DYINRWIFVTITNNRLNNS
Position: 1009-1027
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 12
Chemical type: Peptide from protein
Sequence: DYINRWIFVTITNNRLNNS
Position: 1009-1027
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 12
Chemical type: Peptide from protein
Sequence: DYINRWIFVTITNNRLNNS
Position: 1009-1027
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 15
Chemical type: Peptide from protein
Sequence: NNIMFKLDGCRDTHRYIWI
Position: 1051-1069
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-8 weeks

Epitope: 15
Chemical type: Peptide from protein
Sequence: NNIMFKLDGCRDTHRYIWI
Position: 1051-1069
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 15
Chemical type: Peptide from protein
Sequence: NNIMFKLDGCRDTHRYIWI
Position: 1051-1069
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 15
Chemical type: Peptide from protein
Sequence: NNIMFKLDGCRDTHRYIWI
Position: 1051-1069
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 17
Chemical type: Peptide from protein
Sequence: LNEKEIKDLYDNQSNSGIL
Position: 1079-1097
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 17
Chemical type: Peptide from protein
Sequence: LNEKEIKDLYDNQSNSGIL
Position: 1079-1097
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 17
Chemical type: Peptide from protein
Sequence: LNEKEIKDLYDNQSNSGIL
Position: 1079-1097
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 17
Chemical type: Peptide from protein
Sequence: LNEKEIKDLYDNQSNSGIL
Position: 1079-1097
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 18
Chemical type: Peptide from protein
Sequence: NSGILKDFWGDYLQYDKPY
Position: 1093-1111
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 18
Chemical type: Peptide from protein
Sequence: NSGILKDFWGDYLQYDKPY
Position: 1093-1111
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 18
Chemical type: Peptide from protein
Sequence: NSGILKDFWGDYLQYDKPY
Position: 1093-1111
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 18
Chemical type: Peptide from protein
Sequence: NSGILKDFWGDYLQYDKPY
Position: 1093-1111
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 21
Chemical type: Peptide from protein
Sequence: YLKGPRGSVMTTNIYLNSS
Position: 1135-1153
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 21
Chemical type: Peptide from protein
Sequence: YLKGPRGSVMTTNIYLNSS
Position: 1135-1153
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 21
Chemical type: Peptide from protein
Sequence: YLKGPRGSVMTTNIYLNSS
Position: 1135-1153
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 21
Chemical type: Peptide from protein
Sequence: YLKGPRGSVMTTNIYLNSS
Position: 1135-1153
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 24
Chemical type: Peptide from protein
Sequence: NDRVYINVVVKNKEYRLAT
Position: 1177-1195
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 24
Chemical type: Peptide from protein
Sequence: NDRVYINVVVKNKEYRLAT
Position: 1177-1195
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-8 weeks

Epitope: 24
Chemical type: Peptide from protein
Sequence: NDRVYINVVVKNKEYRLAT
Position: 1177-1195
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 24
Chemical type: Peptide from protein
Sequence: NDRVYINVVVKNKEYRLAT
Position: 1177-1195
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 24
Chemical type: Peptide from protein
Sequence: NDRVYINVVVKNKEYRLAT
Position: 1177-1195
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 24
Chemical type: Peptide from protein
Sequence: NDRVYINVVVKNKEYRLAT
Position: 1177-1195
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 24
Chemical type: Peptide from protein
Sequence: NDRVYINVVVKNKEYRLAT
Position: 1177-1195
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 24
Chemical type: Peptide from protein
Sequence: NDRVYINVVVKNKEYRLAT
Position: 1177-1195
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 31
Chemical type: Peptide from protein
Sequence: SRTLGCSWEFIPVDDGWGERPL
Position: 1275-1296
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 31
Chemical type: Peptide from protein
Sequence: SRTLGCSWEFIPVDDGWGERPL
Position: 1275-1296
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 31
Chemical type: Peptide from protein
Sequence: SRTLGCSWEFIPVDDGWGERPL
Position: 1275-1296
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-8 weeks

Epitope: 31
Chemical type: Peptide from protein
Sequence: SRTLGCSWEFIPVDDGWGERPL
Position: 1275-1296
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-8 weeks

Epitope: 31
Chemical type: Peptide from protein
Sequence: SRTLGCSWEFIPVDDGWGERPL
Position: 1275-1296
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 31
Chemical type: Peptide from protein
Sequence: SRTLGCSWEFIPVDDGWGERPL
Position: 1275-1296
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 31
Chemical type: Peptide from protein
Sequence: SRTLGCSWEFIPVDDGWGERPL
Position: 1275-1296
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 31
Chemical type: Peptide from protein
Sequence: SRTLGCSWEFIPVDDGWGERPL
Position: 1275-1296
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo