Reference: David G Alleva; Amitabh Gaur; Liping Jin; Dale Wegmann; Peter A Gottlieb; Anil Pahuja; Eric B Johnson; Theresa Motheral; Amy Putnam; Paul D Crowe; Nicholas Ling; Stefen A Boehme; Paul J Conlon. "Immunological characterization and therapeutic activity of an altered-peptide ligand, NBI-6024, based on the immunodominant type 1 diabetes autoantigen insulin B-chain (9-23) peptide." Diabetes (2002).

Epitope: insulin B (9-23)
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 9-23
Source molecule (GenBank): 1XDA_B
Assay category: TCell
Result: Positive
Host: F 4 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: insulin B (9-23)
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 9-23
Source molecule (GenBank): 1XDA_B
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone

Epitope: insulin B (9-23)
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 9-23
Source molecule (GenBank): 1XDA_B
Assay category: TCell
Result: Positive
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: insulin B (9-23)
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 9-23
Source molecule (GenBank): 1XDA_B
Assay category: TCell
Result: Positive
Host: F 4 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: insulin B (9-23)
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 9-23
Source molecule (GenBank): 1XDA_B
Assay category: TCell
Result: Positive
Host: F 4 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: insulin B (9-23) A<sup>13,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVAALYLVAGERG
Assay category: TCell
Result: Positive-Low
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: insulin B (9-23) A<sup>13,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVAALYLVAGERG
Assay category: TCell
Result: Positive-High
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: insulin B (9-23) A<sup>13,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVAALYLVAGERG
Assay category: TCell
Result: Positive-High
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: insulin B (9-23) A<sup>13,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVAALYLVAGERG
Assay category: TCell
Result: Positive-Low
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: insulin B (9-23) A<sup>13,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVAALYLVAGERG
Assay category: TCell
Result: Positive
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: insulin B (9-23) A<sup>15,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVEAAYLVAGERG
Assay category: TCell
Result: Positive
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: insulin B (9-23) A<sup>15,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVEAAYLVAGERG
Assay category: TCell
Result: Positive-Low
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: insulin B (9-23) A<sup>15,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVEAAYLVAGERG
Assay category: TCell
Result: Positive
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: insulin B (9-23) A<sup>15,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVEAAYLVAGERG
Assay category: TCell
Result: Positive-High
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: insulin B (9-23) A<sup>15,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVEAAYLVAGERG
Assay category: TCell
Result: Positive-Low
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: insulin B (9-23) A<sup>16,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVEALALVAGERG
Assay category: TCell
Result: Positive
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: insulin B (9-23) A<sup>16,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVEALALVAGERG
Assay category: TCell
Result: Positive-High
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: insulin B (9-23) A<sup>16,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVEALALVAGERG
Assay category: TCell
Result: Positive
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: insulin B (9-23) A<sup>16,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVEALALVAGERG
Assay category: TCell
Result: Positive
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: insulin B (9-23) A<sup>16,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVEALALVAGERG
Assay category: TCell
Result: Positive-Low
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: insulin B (9-23) A<sup>16,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVEALALVAGERG
Assay category: TCell
Result: Positive-Low
Host: F 4 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: insulin B (9-23) A<sup>16,19</sup>
Chemical type: Peptide, no natural source
Sequence: SHLVEALALVAGERG
Assay category: TCell
Result: Positive
Host: F 4 weeks