Reference: Z Liu; K P Williams; Y H Chang; J A Smith. "Immunodominance: a single amino acid substitution within an antigenic site alters intramolecular selection of T cell determinants." Journal of immunology (Baltimore, Md. : 1950) (1993).

Epitope: A90L
Chemical type: Peptide, no natural source
Sequence: GRGLLYIYADGKMVN
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: A90L
Chemical type: Peptide, no natural source
Sequence: GRGLLYIYADGKMVN
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: A90L
Chemical type: Peptide, no natural source
Sequence: GRGLLYIYADGKMVN
Assay category: MhcBinding
Result: Negative

Epitope: Nase 1-20
Chemical type: Peptide from protein
Sequence: ATSTKKLHKEPATLIKAIDG
Position: 83-102
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 1-20
Chemical type: Peptide from protein
Sequence: ATSTKKLHKEPATLIKAIDG
Position: 83-102
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 1-20
Chemical type: Peptide from protein
Sequence: ATSTKKLHKEPATLIKAIDG
Position: 83-102
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 11-30
Chemical type: Peptide from protein
Sequence: PATLIKAIDGDTVKLMYKGQ
Position: 93-112
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 31-50
Chemical type: Peptide from protein
Sequence: PMTFRLLLVDTPETKHPKKG
Position: 113-132
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 41-60
Chemical type: Peptide from protein
Sequence: TPETKHPKKGVEKYGPEASA
Position: 123-142
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 51-70
Chemical type: Peptide from protein
Sequence: VEKYGPEASAFTKKMVENAK
Position: 133-152
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 71-90
Chemical type: Peptide from protein
Sequence: KIEVEFDKGQRTDKYGRGLA
Position: 153-172
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 91-110
Chemical type: Peptide from protein
Sequence: YIYADGKMVNEALVRQGLAK
Position: 173-192
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: Nase 91-110
Chemical type: Peptide from protein
Sequence: YIYADGKMVNEALVRQGLAK
Position: 173-192
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 91-110
Chemical type: Peptide from protein
Sequence: YIYADGKMVNEALVRQGLAK
Position: 173-192
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 91-110
Chemical type: Peptide from protein
Sequence: YIYADGKMVNEALVRQGLAK
Position: 173-192
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 101-120
Chemical type: Peptide from protein
Sequence: EALVRQGLAKVAYVYKPNNT
Position: 183-202
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 101-120
Chemical type: Peptide from protein
Sequence: EALVRQGLAKVAYVYKPNNT
Position: 183-202
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 101-120
Chemical type: Peptide from protein
Sequence: EALVRQGLAKVAYVYKPNNT
Position: 183-202
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 112-130
Chemical type: Peptide from protein
Sequence: AYVYKPNNTHEQHLRKSEA
Position: 194-212
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 112-130
Chemical type: Peptide from protein
Sequence: AYVYKPNNTHEQHLRKSEA
Position: 194-212
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 112-130
Chemical type: Peptide from protein
Sequence: AYVYKPNNTHEQHLRKSEA
Position: 194-212
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 121-140
Chemical type: Peptide from protein
Sequence: HEQHLRKSEAQAKKEKLNIW
Position: 203-222
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 121-140
Chemical type: Peptide from protein
Sequence: HEQHLRKSEAQAKKEKLNIW
Position: 203-222
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 121-140
Chemical type: Peptide from protein
Sequence: HEQHLRKSEAQAKKEKLNIW
Position: 203-222
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Nase 131-149
Chemical type: Peptide from protein
Sequence: QAKKEKLNIWSEDNADSGQ
Position: 213-231
Source molecule (GenBank): P00644.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: A94L
Chemical type: Peptide, no natural source
Sequence: GRGLAYIYLDGKMVN
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: A94L
Chemical type: Peptide, no natural source
Sequence: GRGLAYIYLDGKMVN
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: A94L
Chemical type: Peptide, no natural source
Sequence: GRGLAYIYLDGKMVN
Assay category: MhcBinding
Result: Positive

Epitope: K97L
Chemical type: Peptide, no natural source
Sequence: GRGLAYIYADGLMVN
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: K97L
Chemical type: Peptide, no natural source
Sequence: GRGLAYIYADGLMVN
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: K97L
Chemical type: Peptide, no natural source
Sequence: GRGLAYIYADGLMVN
Assay category: MhcBinding
Result: Positive

Epitope: R87L
Chemical type: Peptide, no natural source
Sequence: GLGLAYIYADGKMVN
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: R87L
Chemical type: Peptide, no natural source
Sequence: GLGLAYIYADGKMVN
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Y93F
Chemical type: Peptide, no natural source
Sequence: GRGLAYIFADGKMVN
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Y93F
Chemical type: Peptide, no natural source
Sequence: GRGLAYIFADGKMVN
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: D95N
Chemical type: Peptide, no natural source
Sequence: GRGLAYIYANGKMVN
Assay category: TCell
Result: Positive-High
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: D95N
Chemical type: Peptide, no natural source
Sequence: GRGLAYIYANGKMVN
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M98L
Chemical type: Peptide, no natural source
Sequence: GRGLAYIYADGKLVN
Assay category: TCell
Result: Positive-High
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M98L
Chemical type: Peptide, no natural source
Sequence: GRGLAYIYADGKLVN
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: N100D
Chemical type: Peptide, no natural source
Sequence: GRGLAYIYADGKMVD
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: N100D
Chemical type: Peptide, no natural source
Sequence: GRGLAYIYADGKMVD
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo