Reference: Zhen Chang; Dan Gao; Liying Liao; Junqing Sun; Gen Zhang; Xue Zhang; Feiran Wang; Chunrui Li; Babayemi Olawale Oladejo; Shihua Li; Yan Chai; Yongfei Hu; Xuancheng Lu; Haixia Xiao; Jianxun Qi; Zhihai Chen; Feng Gao; Yan Wu. "Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model." Proceedings of the National Academy of Sciences of the United States of America (2024).

Epitope: Epitope of SF1 Fab on  SFTSV Gn protein
Chemical type: Discontinuous protein residues
Discontinuous residues: Y83, P84, E86, R91, D226, K244, S317, G320, R332
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.8

Epitope: Epitope of SF1 Fab on  SFTSV Gn protein
Chemical type: Discontinuous protein residues
Discontinuous residues: Y83, P84, E86, R91, D226, K244, S317, G320, R332
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of SF1 Fab on  SFTSV Gn protein
Chemical type: Discontinuous protein residues
Discontinuous residues: Y83, P84, E86, R91, D226, K244, S317, G320, R332
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SF1 Fab on  SFTSV Gn protein
Chemical type: Discontinuous protein residues
Discontinuous residues: Y83, P84, E86, R91, D226, K244, S317, G320, R332
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive
Quantitative measurement: 5.11

Epitope: Epitope of SF5 Fab on SFTSV Gn protein
Chemical type: Discontinuous protein residues
Discontinuous residues: R74, S78, Q79, V80, S81, Y82, Y83, P84, A85, E86, S90, G121, S123, K125, G126, T150, E151, S157, S158, S160, G161, P168, S169, D170, R171
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SF5 Fab on SFTSV Gn protein
Chemical type: Discontinuous protein residues
Discontinuous residues: R74, S78, Q79, V80, S81, Y82, Y83, P84, A85, E86, S90, G121, S123, K125, G126, T150, E151, S157, S158, S160, G161, P168, S169, D170, R171
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SF5 Fab on SFTSV Gn protein
Chemical type: Discontinuous protein residues
Discontinuous residues: R74, S78, Q79, V80, S81, Y82, Y83, P84, A85, E86, S90, G121, S123, K125, G126, T150, E151, S157, S158, S160, G161, P168, S169, D170, R171
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SF5 Fab on SFTSV Gn protein
Chemical type: Discontinuous protein residues
Discontinuous residues: R74, S78, Q79, V80, S81, Y82, Y83, P84, A85, E86, S90, G121, S123, K125, G126, T150, E151, S157, S158, S160, G161, P168, S169, D170, R171
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.51

Epitope: Epitope of SF5 Fab on SFTSV Gn protein
Chemical type: Discontinuous protein residues
Discontinuous residues: R74, S78, Q79, V80, S81, Y82, Y83, P84, A85, E86, S90, G121, S123, K125, G126, T150, E151, S157, S158, S160, G161, P168, S169, D170, R171
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SF5 Fab on SFTSV Gn protein
Chemical type: Discontinuous protein residues
Discontinuous residues: R74, S78, Q79, V80, S81, Y82, Y83, P84, A85, E86, S90, G121, S123, K125, G126, T150, E151, S157, S158, S160, G161, P168, S169, D170, R171
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 339.3

Epitope: Epitope of SF5 Fab on SFTSV Gn protein
Chemical type: Discontinuous protein residues
Discontinuous residues: R74, S78, Q79, V80, S81, Y82, Y83, P84, A85, E86, S90, G121, S123, K125, G126, T150, E151, S157, S158, S160, G161, P168, S169, D170, R171
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SF83 Fab on SFTSV Gc protein
Chemical type: Discontinuous protein residues
Discontinuous residues: C660, F664, F684, S685, G686, C687, S688, D689, W708, K710, N826, A827, D828, G831, I832, E833, R835, V836, Y842, K844
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of SF83 Fab on SFTSV Gc protein
Chemical type: Discontinuous protein residues
Discontinuous residues: C660, F664, F684, S685, G686, C687, S688, D689, W708, K710, N826, A827, D828, G831, I832, E833, R835, V836, Y842, K844
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SF83 Fab on SFTSV Gc protein
Chemical type: Discontinuous protein residues
Discontinuous residues: C660, F664, F684, S685, G686, C687, S688, D689, W708, K710, N826, A827, D828, G831, I832, E833, R835, V836, Y842, K844
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SF83 Fab on SFTSV Gc protein
Chemical type: Discontinuous protein residues
Discontinuous residues: C660, F664, F684, S685, G686, C687, S688, D689, W708, K710, N826, A827, D828, G831, I832, E833, R835, V836, Y842, K844
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.78

Epitope: Epitope of SF83 Fab on SFTSV Gc protein
Chemical type: Discontinuous protein residues
Discontinuous residues: C660, F664, F684, S685, G686, C687, S688, D689, W708, K710, N826, A827, D828, G831, I832, E833, R835, V836, Y842, K844
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.3

Epitope: Epitope of SF83 Fab on SFTSV Gc protein
Chemical type: Discontinuous protein residues
Discontinuous residues: C660, F664, F684, S685, G686, C687, S688, D689, W708, K710, N826, A827, D828, G831, I832, E833, R835, V836, Y842, K844
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SF83 Fab on SFTSV Gc protein
Chemical type: Discontinuous protein residues
Discontinuous residues: C660, F664, F684, S685, G686, C687, S688, D689, W708, K710, N826, A827, D828, G831, I832, E833, R835, V836, Y842, K844
Source molecule (GenBank): AFB82725.1
Assay category: BCell
Result: Positive