Reference: Luke F Pennington; Pascal Gasser; Silke Kleinboelting; Chensong Zhang; Georgios Skiniotis; Alexander Eggel; Theodore S Jardetzky. "Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex." Nature communications (2021).

Epitope: Epitope of omalizumab scFv on IgE
Chemical type: Discontinuous protein residues
Discontinuous residues: T254, W255, S256, R257, A258, S259, G260, K261, Q298, R300, R308, A309, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive

Epitope: Epitope of omalizumab scFv on IgE
Chemical type: Discontinuous protein residues
Discontinuous residues: T254, W255, S256, R257, A258, S259, G260, K261, Q298, R300, R308, A309, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.0

Epitope: Epitope of omalizumab scFv on IgE
Chemical type: Discontinuous protein residues
Discontinuous residues: T254, W255, S256, R257, A258, S259, G260, K261, Q298, R300, R308, A309, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive
Quantitative measurement: 944000.0

Epitope: Epitope of omalizumab scFv on IgE
Chemical type: Discontinuous protein residues
Discontinuous residues: T254, W255, S256, R257, A258, S259, G260, K261, Q298, R300, R308, A309, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.02

Epitope: Epitope of omalizumab scFv on IgE
Chemical type: Discontinuous protein residues
Discontinuous residues: T254, W255, S256, R257, A258, S259, G260, K261, Q298, R300, R308, A309, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00191

Epitope: Epitope of omalizumab variant 813 on IgE-Fc
Chemical type: Discontinuous protein residues
Discontinuous residues: T254, W255, S256, R257, A258, S259, G260, K261, P262, Q298, R300, T302, R308, A309, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00148

Epitope: Epitope of omalizumab variant 813 on IgE-Fc
Chemical type: Discontinuous protein residues
Discontinuous residues: T254, W255, S256, R257, A258, S259, G260, K261, P262, Q298, R300, T302, R308, A309, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.0

Epitope: Epitope of omalizumab variant 813 on IgE-Fc
Chemical type: Discontinuous protein residues
Discontinuous residues: T254, W255, S256, R257, A258, S259, G260, K261, P262, Q298, R300, T302, R308, A309, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive
Quantitative measurement: 797000.0

Epitope: Epitope of omalizumab variant 813 on IgE-Fc
Chemical type: Discontinuous protein residues
Discontinuous residues: T254, W255, S256, R257, A258, S259, G260, K261, P262, Q298, R300, T302, R308, A309, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive

Epitope: Epitope of omalizumab variant 813 on IgE-Fc
Chemical type: Discontinuous protein residues
Discontinuous residues: T254, W255, S256, R257, A258, S259, G260, K261, P262, Q298, R300, T302, R308, A309, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.86

Epitope: Epitope of omalizumab variant HAE on IgE-Fc
Chemical type: Discontinuous protein residues
Discontinuous residues: T254, W255, S256, R257, A258, S259, G260, K261, Q298, R300, P307, R308, A309, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000254

Epitope: Epitope of omalizumab variant HAE on IgE-Fc
Chemical type: Discontinuous protein residues
Discontinuous residues: T254, W255, S256, R257, A258, S259, G260, K261, Q298, R300, P307, R308, A309, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.0

Epitope: Epitope of omalizumab variant HAE on IgE-Fc
Chemical type: Discontinuous protein residues
Discontinuous residues: T254, W255, S256, R257, A258, S259, G260, K261, Q298, R300, P307, R308, A309, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive

Epitope: Epitope of omalizumab variant HAE on IgE-Fc
Chemical type: Discontinuous protein residues
Discontinuous residues: T254, W255, S256, R257, A258, S259, G260, K261, Q298, R300, P307, R308, A309, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.166

Epitope: Epitope of omalizumab variant HAE on IgE-Fc
Chemical type: Discontinuous protein residues
Discontinuous residues: T254, W255, S256, R257, A258, S259, G260, K261, Q298, R300, P307, R308, A309, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1520000.0

Epitope: Epitope of omalizumab variant clone 7 on IgE-Fc
Chemical type: Discontinuous protein residues
Discontinuous residues: T201, E203, T254, S256, R257, A258, S259, K261, E295, Q298, R300, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1790000.0

Epitope: Epitope of omalizumab variant clone 7 on IgE-Fc
Chemical type: Discontinuous protein residues
Discontinuous residues: T201, E203, T254, S256, R257, A258, S259, K261, E295, Q298, R300, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00104

Epitope: Epitope of omalizumab variant clone 7 on IgE-Fc
Chemical type: Discontinuous protein residues
Discontinuous residues: T201, E203, T254, S256, R257, A258, S259, K261, E295, Q298, R300, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive

Epitope: Epitope of omalizumab variant clone 7 on IgE-Fc
Chemical type: Discontinuous protein residues
Discontinuous residues: T201, E203, T254, S256, R257, A258, S259, K261, E295, Q298, R300, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive

Epitope: Epitope of omalizumab variant clone 7 on IgE-Fc
Chemical type: Discontinuous protein residues
Discontinuous residues: T201, E203, T254, S256, R257, A258, S259, K261, E295, Q298, R300, M311
Source molecule (GenBank): P01854.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.581