Reference: Jin Guo; Pavel N Pichurin; John C Morris; Basil Rapoport; Sandra M McLachlan. "Naked deoxyribonucleic acid vaccination induces recognition of diverse thyroid peroxidase T cell epitopes." Endocrinology (2004).

Epitope: TPO 27–46
Chemical type: Peptide from protein
Sequence: KELLWGKPEESRVSSVLEES
Position: 27-46
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 42–61
Chemical type: Peptide from protein
Sequence: VLEESKRLVDTAMYATMQRN
Position: 42-61
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 57–76
Chemical type: Peptide from protein
Sequence: TMQRNLKKRGILSPAQLLSF
Position: 57-76
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 72–91
Chemical type: Peptide from protein
Sequence: QLLSFSKLPEPTSGVIARAA
Position: 72-91
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 87–106
Chemical type: Peptide from protein
Sequence: IARAAEIMETSIQAMKRKVN
Position: 87-106
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 102–121
Chemical type: Peptide from protein
Sequence: KRKVNLKTQQSQHPTDALSE
Position: 102-121
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 117-136
Chemical type: Peptide from protein
Sequence: DALSEDLLSIIANMSGCLPY
Position: 117-136
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 132–151
Chemical type: Peptide from protein
Sequence: GCLPYMLPPKCPNTCLANKY
Position: 132-151
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 147–166
Chemical type: Peptide from protein
Sequence: LANKYRPITGACNNRDHPRW
Position: 147-166
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 162–181
Chemical type: Peptide from protein
Sequence: DHPRWGASNTALARWLPPVY
Position: 162-181
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 177–196
Chemical type: Peptide from protein
Sequence: LPPVYEDGFSQPRGWNPGFL
Position: 177-196
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 192–211
Chemical type: Peptide from protein
Sequence: NPGFLYNGFPLPPVREVTRH
Position: 192-211
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 207–226
Chemical type: Peptide from protein
Sequence: EVTRHVIQVSNEVVTDDDRY
Position: 207-226
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 222–241
Chemical type: Peptide from protein
Sequence: DDDRYSDLLMAWGQYIDHDI
Position: 222-241
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 237–256
Chemical type: Peptide from protein
Sequence: IDHDIAFTPQSTSKAAFGGG
Position: 237-256
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 252–271
Chemical type: Peptide from protein
Sequence: AFGGGADCQMTCENQNPCFP
Position: 252-271
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 267–286
Chemical type: Peptide from protein
Sequence: NPCFPIQLPEEARPAAGTAC
Position: 267-286
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 282–301
Chemical type: Peptide from protein
Sequence: AGTACLPFYRSSAACGTGDQ
Position: 282-301
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 297–316
Chemical type: Peptide from protein
Sequence: GTGDQGALFGNLSTANPRQQ
Position: 297-316
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 312–331
Chemical type: Peptide from protein
Sequence: NPRQQMNGLTSFLDASTVYG
Position: 312-331
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 327-346
Chemical type: Peptide from protein
Sequence: STVYGSSPALERQLRNWTSA
Position: 327-346
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 342–362
Chemical type: Peptide from protein
Sequence: NWTSAEGLLRVHARLRDSGR
Position: 342-361
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 357–376
Chemical type: Peptide from protein
Sequence: RDSGRAYLPFVPPRRPAACA
Position: 357-376
Source molecule (GenBank): AAA61216.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 372–391
Chemical type: Peptide from protein
Sequence: PAACAPEPGIPGETRGPCFL
Position: 372-391
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 387–406
Chemical type: Peptide from protein
Sequence: GPCFLAGDGRASEVPSLTAL
Position: 387-406
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 402-422
Chemical type: Peptide from protein
Sequence: SLTALHTLWLREHNRLAAAL
Position: 402-421
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 417–436
Chemical type: Peptide from protein
Sequence: LAAALKALNAHWSADAVYQE
Position: 417-436
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 432–451
Chemical type: Peptide from protein
Sequence: AVYQEARKVVGALHQIITLR
Position: 432-451
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 447–466
Chemical type: Peptide from protein
Sequence: IITLRDYIPRILGPEAFQQY
Position: 447-466
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 477–496
Chemical type: Peptide from protein
Sequence: ANPTVSNVFSTAAFRFGHAT
Position: 477-496
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 492–511
Chemical type: Peptide from protein
Sequence: FGHATIHPLVRRLDASFQEH
Position: 492-511
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 507–526
Chemical type: Peptide from protein
Sequence: SFQEHPDLPGLWLHQAFFSP
Position: 507-526
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 522–541
Chemical type: Peptide from protein
Sequence: AFFSPWTLLRGGGLDPLIRG
Position: 522-541
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 552–571
Chemical type: Peptide from protein
Sequence: QDQLMNEELTERLFVLSNSS
Position: 552-571
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 567–586
Chemical type: Peptide from protein
Sequence: LSNSSTLDLASINLQRGRDH
Position: 567-586
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 582–601
Chemical type: Peptide from protein
Sequence: RGRDHGLPGYNEWREFCGLP
Position: 582-601
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 597–616
Chemical type: Peptide from protein
Sequence: FCGLPRLETPADLSTAIASR
Position: 597-616
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 612–631
Chemical type: Peptide from protein
Sequence: AIASRSVADKILDLYKHPDN
Position: 612-631
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 627–646
Chemical type: Peptide from protein
Sequence: KHPDNIDVWLGGLAENFLPR
Position: 627-646
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 657–676
Chemical type: Peptide from protein
Sequence: IGKQMKALRDGDWFWWENSH
Position: 657-676
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 672–791
Chemical type: Peptide from protein
Sequence: WENSHVFTDAQRRELEKHSL
Position: 672-691
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 687–706
Chemical type: Peptide from protein
Sequence: EKHSLSRVICDNTGLTRVPM
Position: 687-706
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 702–721
Chemical type: Peptide from protein
Sequence: TRVPMDAFQVGKFPEDFESC
Position: 702-721
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 717–736
Chemical type: Peptide from protein
Sequence: DFESCDSIPGMNLEAWRETF
Position: 717-736
Source molecule (GenBank): CAA68467.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 732–751
Chemical type: Peptide from protein
Sequence: WRETFPQDDKCGFPESVENG
Position: 732-751
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 747–766
Chemical type: Peptide from protein
Sequence: SVENGDFVHCEESGRRVLVY
Position: 747-766
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 762–781
Chemical type: Peptide from protein
Sequence: RVLVYSCRHGYELQGREQLT
Position: 762-781
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 777–796
Chemical type: Peptide from protein
Sequence: REQLTCTQEGWDFQPPLCKD
Position: 777-796
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 792–811
Chemical type: Peptide from protein
Sequence: PLCKDVNECADGAHPPCHAS
Position: 792-811
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 807–826
Chemical type: Peptide from protein
Sequence: PCHASARCRNTKGGFQCLCA
Position: 807-826
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 822–841
Chemical type: Peptide from protein
Sequence: QCLCADPYELGDDGRTCVDS
Position: 822-841
Source molecule (GenBank): P07202.4
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TPO 837–853
Chemical type: Peptide from protein
Sequence: TCVDSGRLPRATWISMS
Position: 837-853
Source molecule (GenBank): CAA68467.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo