Reference: Xavier Dervillez; Huma Qureshi; Aziz A Chentoufi; Arif A Khan; Elizabeth Kritzer; David C Yu; Oscar R Diaz; Chetan Gottimukkala; Mina Kalantari; Maria C Villacres; Vanessa M Scarfone; Denise M McKinney; John Sidney; Alessandro Sette; Anthony B Nesburn; Steven L Wechsler; Lbachir BenMohamed. "Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes." Journal of immunology (Baltimore, Md. : 1950) (2013).

Epitope: gB 17-25
Chemical type: Peptide from protein
Sequence: ALLGLTLGV
Position: 17-25
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 17-25
Chemical type: Peptide from protein
Sequence: ALLGLTLGV
Position: 17-25
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 17-25
Chemical type: Peptide from protein
Sequence: ALLGLTLGV
Position: 17-25
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 17-25
Chemical type: Peptide from protein
Sequence: ALLGLTLGV
Position: 17-25
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 17-25
Chemical type: Peptide from protein
Sequence: ALLGLTLGV
Position: 17-25
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 17-25
Chemical type: Peptide from protein
Sequence: ALLGLTLGV
Position: 17-25
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: gB 17-25
Chemical type: Peptide from protein
Sequence: ALLGLTLGV
Position: 17-25
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 25.0

Epitope: gB 161–169
Chemical type: Peptide from protein
Sequence: TMYYKDVTV
Position: 162-170
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 161–169
Chemical type: Peptide from protein
Sequence: TMYYKDVTV
Position: 162-170
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 161–169
Chemical type: Peptide from protein
Sequence: TMYYKDVTV
Position: 162-170
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 161–169
Chemical type: Peptide from protein
Sequence: TMYYKDVTV
Position: 162-170
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Negative
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 161–169
Chemical type: Peptide from protein
Sequence: TMYYKDVTV
Position: 162-170
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 25.0

Epitope: gB 161–169
Chemical type: Peptide from protein
Sequence: TMYYKDVTV
Position: 162-170
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Positive-High

Epitope: gB 183–191
Chemical type: Peptide from protein
Sequence: GIFEDRAPV
Position: 184-192
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive-Low
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: gB 183–191
Chemical type: Peptide from protein
Sequence: GIFEDRAPV
Position: 184-192
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive-Low
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: gB 183–191
Chemical type: Peptide from protein
Sequence: GIFEDRAPV
Position: 184-192
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 183–191
Chemical type: Peptide from protein
Sequence: GIFEDRAPV
Position: 184-192
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 183–191
Chemical type: Peptide from protein
Sequence: GIFEDRAPV
Position: 184-192
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 183–191
Chemical type: Peptide from protein
Sequence: GIFEDRAPV
Position: 184-192
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 183–191
Chemical type: Peptide from protein
Sequence: GIFEDRAPV
Position: 184-192
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 183–191
Chemical type: Peptide from protein
Sequence: GIFEDRAPV
Position: 184-192
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 500.0

Epitope: gB 183–191
Chemical type: Peptide from protein
Sequence: GIFEDRAPV
Position: 184-192
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Negative

Epitope: gB 286–294
Chemical type: Peptide from protein
Sequence: FVLATGDFV
Position: 287-295
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 286–294
Chemical type: Peptide from protein
Sequence: FVLATGDFV
Position: 287-295
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 286–294
Chemical type: Peptide from protein
Sequence: FVLATGDFV
Position: 287-295
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Negative
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 286–294
Chemical type: Peptide from protein
Sequence: FVLATGDFV
Position: 287-295
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Negative
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 286–294
Chemical type: Peptide from protein
Sequence: FVLATGDFV
Position: 287-295
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 500.0

Epitope: gB 286–294
Chemical type: Peptide from protein
Sequence: FVLATGDFV
Position: 287-295
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Negative

Epitope: gB 342–350
Chemical type: Peptide from protein
Sequence: NLLTTPKFT
Position: 343-351
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: gB 342–350
Chemical type: Peptide from protein
Sequence: NLLTTPKFT
Position: 343-351
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: gB 342–350
Chemical type: Peptide from protein
Sequence: NLLTTPKFT
Position: 343-351
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 342–350
Chemical type: Peptide from protein
Sequence: NLLTTPKFT
Position: 343-351
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 342–350
Chemical type: Peptide from protein
Sequence: NLLTTPKFT
Position: 343-351
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 342–350
Chemical type: Peptide from protein
Sequence: NLLTTPKFT
Position: 343-351
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 342–350
Chemical type: Peptide from protein
Sequence: NLLTTPKFT
Position: 343-351
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 342–350
Chemical type: Peptide from protein
Sequence: NLLTTPKFT
Position: 343-351
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 500.0

Epitope: gB 342–350
Chemical type: Peptide from protein
Sequence: NLLTTPKFT
Position: 343-351
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Negative

Epitope: gB 343–351
Chemical type: Peptide from protein
Sequence: LLTTPKFTV
Position: 344-352
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 343–351
Chemical type: Peptide from protein
Sequence: LLTTPKFTV
Position: 344-352
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Negative
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 343–351
Chemical type: Peptide from protein
Sequence: LLTTPKFTV
Position: 344-352
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Negative
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 343–351
Chemical type: Peptide from protein
Sequence: LLTTPKFTV
Position: 344-352
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Negative
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 343–351
Chemical type: Peptide from protein
Sequence: LLTTPKFTV
Position: 344-352
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Negative

Epitope: gB 343–351
Chemical type: Peptide from protein
Sequence: LLTTPKFTV
Position: 344-352
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 500.0

Epitope: gB 441–449
Chemical type: Peptide from protein
Sequence: YLANGGFLI
Position: 442-450
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive-Low
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: gB 441–449
Chemical type: Peptide from protein
Sequence: YLANGGFLI
Position: 442-450
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive-Low
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: gB 441–449
Chemical type: Peptide from protein
Sequence: YLANGGFLI
Position: 442-450
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 441–449
Chemical type: Peptide from protein
Sequence: YLANGGFLI
Position: 442-450
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 441–449
Chemical type: Peptide from protein
Sequence: YLANGGFLI
Position: 442-450
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 441–449
Chemical type: Peptide from protein
Sequence: YLANGGFLI
Position: 442-450
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 441–449
Chemical type: Peptide from protein
Sequence: YLANGGFLI
Position: 442-450
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 441–449
Chemical type: Peptide from protein
Sequence: YLANGGFLI
Position: 442-450
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Positive-High

Epitope: gB 441–449
Chemical type: Peptide from protein
Sequence: YLANGGFLI
Position: 442-450
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 25.0

Epitope: gB 447–455
Chemical type: Peptide from protein
Sequence: FLIAYQPLL
Position: 448-456
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 447–455
Chemical type: Peptide from protein
Sequence: FLIAYQPLL
Position: 448-456
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Negative
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 447–455
Chemical type: Peptide from protein
Sequence: FLIAYQPLL
Position: 448-456
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Negative
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 447–455
Chemical type: Peptide from protein
Sequence: FLIAYQPLL
Position: 448-456
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Negative
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 447–455
Chemical type: Peptide from protein
Sequence: FLIAYQPLL
Position: 448-456
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Positive-High

Epitope: gB 447–455
Chemical type: Peptide from protein
Sequence: FLIAYQPLL
Position: 448-456
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 25.0

Epitope: gB 561–569
Chemical type: Peptide from protein
Sequence: RMLGDVMAV
Position: 562-570
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: gB 561–569
Chemical type: Peptide from protein
Sequence: RMLGDVMAV
Position: 562-570
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: gB 561–569
Chemical type: Peptide from protein
Sequence: RMLGDVMAV
Position: 562-570
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 561–569
Chemical type: Peptide from protein
Sequence: RMLGDVMAV
Position: 562-570
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 561–569
Chemical type: Peptide from protein
Sequence: RMLGDVMAV
Position: 562-570
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 561–569
Chemical type: Peptide from protein
Sequence: RMLGDVMAV
Position: 562-570
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 561–569
Chemical type: Peptide from protein
Sequence: RMLGDVMAV
Position: 562-570
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 561–569
Chemical type: Peptide from protein
Sequence: RMLGDVMAV
Position: 562-570
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Positive-High

Epitope: gB 561–569
Chemical type: Peptide from protein
Sequence: RMLGDVMAV
Position: 562-570
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 25.0

Epitope: gB 675–683
Chemical type: Peptide from protein
Sequence: TMLEDHEFV
Position: 676-684
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 675–683
Chemical type: Peptide from protein
Sequence: TMLEDHEFV
Position: 676-684
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 675–683
Chemical type: Peptide from protein
Sequence: TMLEDHEFV
Position: 676-684
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Negative
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 675–683
Chemical type: Peptide from protein
Sequence: TMLEDHEFV
Position: 676-684
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Negative
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gB 675–683
Chemical type: Peptide from protein
Sequence: TMLEDHEFV
Position: 676-684
Source molecule (GenBank): NP_044629.1
Assay category: TCell
Result: Negative
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gB 675–683
Chemical type: Peptide from protein
Sequence: TMLEDHEFV
Position: 676-684
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Positive-High

Epitope: gB 675–683
Chemical type: Peptide from protein
Sequence: TMLEDHEFV
Position: 676-684
Source molecule (GenBank): NP_044629.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 100.0