Reference: Hideo Nakamura; Kunihiko Yamaki; Isao Kondo; Shozo Sakuragi. "Experimental autoimmune uveitis induced by immunization with retinal pigment epithelium-specific 65-kDa protein peptides." Current eye research (2005).

Epitope: RPE65-1
Chemical type: Peptide from protein
Sequence: MSIQVEHPAGGYKKLFETVEELSSPLTAHV
Position: 1-30
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Positive
Host: M 4-6 weeks

Epitope: RPE65-1
Chemical type: Peptide from protein
Sequence: MSIQVEHPAGGYKKLFETVEELSSPLTAHV
Position: 1-30
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Positive
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-1
Chemical type: Peptide from protein
Sequence: MSIQVEHPAGGYKKLFETVEELSSPLTAHV
Position: 1-30
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Positive
Host: M 4-6 weeks

Epitope: RPE65-2
Chemical type: Peptide from protein
Sequence: FETVEELSSPLTAHVTGRIPLWLTGSLLRCGP
Position: 16-47
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-2
Chemical type: Peptide from protein
Sequence: FETVEELSSPLTAHVTGRIPLWLTGSLLRCGP
Position: 16-47
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-2
Chemical type: Peptide from protein
Sequence: FETVEELSSPLTAHVTGRIPLWLTGSLLRCGP
Position: 16-47
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-3
Chemical type: Peptide from protein
Sequence: LTGSLLRCGPGLFEVGSEPFYHLFDGQALL
Position: 38-67
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-3
Chemical type: Peptide from protein
Sequence: LTGSLLRCGPGLFEVGSEPFYHLFDGQALL
Position: 38-67
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-3
Chemical type: Peptide from protein
Sequence: LTGSLLRCGPGLFEVGSEPFYHLFDGQALL
Position: 38-67
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-6
Chemical type: Peptide from protein
Sequence: KRIVITEFGTCAFPDPCKNIFSRFFSYFRG
Position: 96-125
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-6
Chemical type: Peptide from protein
Sequence: KRIVITEFGTCAFPDPCKNIFSRFFSYFRG
Position: 96-125
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-6
Chemical type: Peptide from protein
Sequence: KRIVITEFGTCAFPDPCKNIFSRFFSYFRG
Position: 96-125
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-8
Chemical type: Peptide from protein
Sequence: VYPVGEDYYACTETNFITKINPETLETIKQ
Position: 136-165
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-8
Chemical type: Peptide from protein
Sequence: VYPVGEDYYACTETNFITKINPETLETIKQ
Position: 136-165
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-8
Chemical type: Peptide from protein
Sequence: VYPVGEDYYACTETNFITKINPETLETIKQ
Position: 136-165
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-9
Chemical type: Peptide from protein
Sequence: NPETLETIKQVDLCNYVSVNGATAHPHIEN
Position: 156-185
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-9
Chemical type: Peptide from protein
Sequence: NPETLETIKQVDLCNYVSVNGATAHPHIEN
Position: 156-185
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-9
Chemical type: Peptide from protein
Sequence: NPETLETIKQVDLCNYVSVNGATAHPHIEN
Position: 156-185
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Positive
Host: M 4-6 weeks

Epitope: RPE65-10
Chemical type: Peptide from protein
Sequence: GATAHPHIENDGTVYNIGNCFGKNFSIAYN
Position: 176-205
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-10
Chemical type: Peptide from protein
Sequence: GATAHPHIENDGTVYNIGNCFGKNFSIAYN
Position: 176-205
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-10
Chemical type: Peptide from protein
Sequence: GATAHPHIENDGTVYNIGNCFGKNFSIAYN
Position: 176-205
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-11
Chemical type: Peptide from protein
Sequence: FGKNFSIAYNIVKIPPLQADKEDPISKSEI
Position: 196-225
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-11
Chemical type: Peptide from protein
Sequence: FGKNFSIAYNIVKIPPLQADKEDPISKSEI
Position: 196-225
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-11
Chemical type: Peptide from protein
Sequence: FGKNFSIAYNIVKIPPLQADKEDPISKSEI
Position: 196-225
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-12
Chemical type: Peptide from protein
Sequence: KEDPISKSEIVVQFPCSDRFKPSYVHSFGL
Position: 216-245
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-12
Chemical type: Peptide from protein
Sequence: KEDPISKSEIVVQFPCSDRFKPSYVHSFGL
Position: 216-245
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-12
Chemical type: Peptide from protein
Sequence: KEDPISKSEIVVQFPCSDRFKPSYVHSFGL
Position: 216-245
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-13
Chemical type: Peptide from protein
Sequence: FKPSYVHSFGLTPNYIVFVETPVKINLFKFL
Position: 235-265
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-13
Chemical type: Peptide from protein
Sequence: FKPSYVHSFGLTPNYIVFVETPVKINLFKFL
Position: 235-265
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-13
Chemical type: Peptide from protein
Sequence: FKPSYVHSFGLTPNYIVFVETPVKINLFKFL
Position: 235-265
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-14
Chemical type: Peptide from protein
Sequence: PVKINLFKFLSSWSLWGANYMDCFESNETM
Position: 256-285
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-14
Chemical type: Peptide from protein
Sequence: PVKINLFKFLSSWSLWGANYMDCFESNETM
Position: 256-285
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-14
Chemical type: Peptide from protein
Sequence: PVKINLFKFLSSWSLWGANYMDCFESNETM
Position: 256-285
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Positive
Host: M 4-6 weeks

Epitope: RPE65-16
Chemical type: Peptide from protein
Sequence: RKKYLNNKYRTSPFNLFHHINTYEDNGFLIV
Position: 296-326
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-16
Chemical type: Peptide from protein
Sequence: RKKYLNNKYRTSPFNLFHHINTYEDNGFLIV
Position: 296-326
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Positive
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-16
Chemical type: Peptide from protein
Sequence: RKKYLNNKYRTSPFNLFHHINTYEDNGFLIV
Position: 296-326
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Positive
Host: M 4-6 weeks

Epitope: RPE65-17
Chemical type: Peptide from protein
Sequence: TYEDNGFLIVDLCCWKGFEFVYNYLYLANLRENW
Position: 317-350
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-17
Chemical type: Peptide from protein
Sequence: TYEDNGFLIVDLCCWKGFEFVYNYLYLANLRENW
Position: 317-350
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-17
Chemical type: Peptide from protein
Sequence: TYEDNGFLIVDLCCWKGFEFVYNYLYLANLRENW
Position: 317-350
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Positive
Host: M 4-6 weeks

Epitope: RPE65-18
Chemical type: Peptide from protein
Sequence: VYNYLYLANLRENWEEVKKNARKAPQPEV
Position: 337-365
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-18
Chemical type: Peptide from protein
Sequence: VYNYLYLANLRENWEEVKKNARKAPQPEV
Position: 337-365
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-18
Chemical type: Peptide from protein
Sequence: VYNYLYLANLRENWEEVKKNARKAPQPEV
Position: 337-365
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-19
Chemical type: Peptide from protein
Sequence: NARKAPQPEVRRYVLPLNIDKADTGKNLVT
Position: 356-385
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-19
Chemical type: Peptide from protein
Sequence: NARKAPQPEVRRYVLPLNIDKADTGKNLVT
Position: 356-385
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-19
Chemical type: Peptide from protein
Sequence: NARKAPQPEVRRYVLPLNIDKADTGKNLVT
Position: 356-385
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Positive
Host: M 4-6 weeks

Epitope: RPE65-20
Chemical type: Peptide from protein
Sequence: KADTGKNLVTLPNTTATAILCSDETIWLEP
Position: 376-405
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-20
Chemical type: Peptide from protein
Sequence: KADTGKNLVTLPNTTATAILCSDETIWLEP
Position: 376-405
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-20
Chemical type: Peptide from protein
Sequence: KADTGKNLVTLPNTTATAILCSDETIWLEP
Position: 376-405
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-21
Chemical type: Peptide from protein
Sequence: CSDETIWLEPEVLFSGPRQAFEFPQINYQK
Position: 396-425
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Positive
Host: M 4-6 weeks

Epitope: RPE65-21
Chemical type: Peptide from protein
Sequence: CSDETIWLEPEVLFSGPRQAFEFPQINYQK
Position: 396-425
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Positive
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-21
Chemical type: Peptide from protein
Sequence: CSDETIWLEPEVLFSGPRQAFEFPQINYQK
Position: 396-425
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Positive
Host: M 4-6 weeks

Epitope: RPE65-22
Chemical type: Peptide from protein
Sequence: FEFPQINYQKYCGKPYTYAYGLGLNHFVPD
Position: 416-445
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-22
Chemical type: Peptide from protein
Sequence: FEFPQINYQKYCGKPYTYAYGLGLNHFVPD
Position: 416-445
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-22
Chemical type: Peptide from protein
Sequence: FEFPQINYQKYCGKPYTYAYGLGLNHFVPD
Position: 416-445
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-24
Chemical type: Peptide from protein
Sequence: DSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKP
Position: 464-499
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-24
Chemical type: Peptide from protein
Sequence: DSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKP
Position: 464-499
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-24
Chemical type: Peptide from protein
Sequence: DSYPSEPIFVSHPDALEEDDGVVLSVVVSPGAGQKP
Position: 464-499
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Positive
Host: M 4-6 weeks

Epitope: RPE65-25
Chemical type: Peptide from protein
Sequence: GVVLSVVVSPGAGQKPAYLLILNAKDLSEV
Position: 484-513
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-25
Chemical type: Peptide from protein
Sequence: GVVLSVVVSPGAGQKPAYLLILNAKDLSEV
Position: 484-513
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-25
Chemical type: Peptide from protein
Sequence: GVVLSVVVSPGAGQKPAYLLILNAKDLSEV
Position: 484-513
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Positive
Host: M 4-6 weeks

Epitope: RPE65-26
Chemical type: Peptide from protein
Sequence: ILNAKDLSEVARAEVEINIPVTFHGLFKKS
Position: 504-533
Source molecule (GenBank): AAA99012.1
Assay category: BCell
Result: Negative
Host: M 4-6 weeks

Epitope: RPE65-26
Chemical type: Peptide from protein
Sequence: ILNAKDLSEVARAEVEINIPVTFHGLFKKS
Position: 504-533
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RPE65-26
Chemical type: Peptide from protein
Sequence: ILNAKDLSEVARAEVEINIPVTFHGLFKKS
Position: 504-533
Source molecule (GenBank): AAA99012.1
Assay category: TCell
Result: Negative
Host: M 4-6 weeks