Reference: Menno van Lummel; Peter A van Veelen; Arnoud H de Ru; George M C Janssen; Jos Pool; Sandra Laban; Antoinette M Joosten; Tatjana Nikolic; Jan W Drijfhout; M Luisa Mearin; Henk J Aanstoot; Mark Peakman; Bart O Roep. "Dendritic Cells Guide Islet Autoimmunity through a Restricted and Uniquely Processed Peptidome Presented by High-Risk HLA-DR." Journal of immunology (Baltimore, Md. : 1950) (2016).

Chemical type: Peptide from protein
Sequence: LALWGPDPAAA
Position: 14-24
Source molecule (GenBank): AAA59179.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: LALWGPDPAAA
Position: 14-24
Source molecule (GenBank): AAA59179.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 8700.0

Chemical type: Peptide from protein
Sequence: LALWGPDPAAA
Position: 14-24
Source molecule (GenBank): AAA59179.1
Assay category: MhcBinding
Result: Negative

Chemical type: Peptide from protein
Sequence: LALWGPDPAAAFVNQHL
Position: 14-30
Source molecule (GenBank): AAA59179.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: LALWGPDPAAAFVNQHL
Position: 14-30
Source molecule (GenBank): AAA59179.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 83000.0

Chemical type: Peptide from protein
Sequence: LALWGPDPAAAFVNQHL
Position: 14-30
Source molecule (GenBank): AAA59179.1
Assay category: MhcBinding
Result: Negative

Chemical type: Peptide from protein
Sequence: WGPDPAAA
Position: 17-24
Source molecule (GenBank): AAA59179.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: WGPDPAAA
Position: 17-24
Source molecule (GenBank): AAA59179.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: WGPDPAAA
Position: 17-24
Source molecule (GenBank): AAA59179.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 700.0

Chemical type: Peptide from protein
Sequence: WGPDPAAA
Position: 17-24
Source molecule (GenBank): AAA59179.1
Assay category: MhcBinding
Result: Negative

Chemical type: Peptide from protein
Sequence: WGPDPAA
Position: 17-23
Source molecule (GenBank): AAA59179.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: WGPDPAA
Position: 17-23
Source molecule (GenBank): AAA59179.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: LPGPSPAQLFQDSGLLYLAQ
Position: 264-283
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: LPGPSPAQLFQDSGLLYLAQE
Position: 264-284
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: LPGPSPAQLFQDSGLLYLAQE
Position: 264-284
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  child
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: LPGPSPAQLFQDSGLLYLAQE
Position: 264-284
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: LPGPSPAQLFQDSGLLYLAQE
Position: 264-284
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: LPGPSPAQLFQDSGLLYLAQE
Position: 264-284
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: LPGPSPAQLFQDSGLLYLAQE
Position: 264-284
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 42600.0

Chemical type: Peptide from protein
Sequence: LPGPSPAQLFQDSGLLYLAQE
Position: 264-284
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 51800.0

Chemical type: Peptide from protein
Sequence: SPAQLFQDSGLLYLAQ
Position: 268-283
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: DRGEKPASPAVQPD
Position: 319-332
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: DRGEKPASPAVQPDAALQRLAA
Position: 319-340
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: DRGEKPASPAVQPDAALQRLAAV
Position: 319-341
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: GEKPASPAVQPDAALQRLAAV
Position: 321-341
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: KPASPAVQPDAALQRL
Position: 323-338
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: KPASPAVQPDAALQRLA
Position: 323-339
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: KPASPAVQPDAALQRLAA
Position: 323-340
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: KPASPAVQPDAALQRLAAV
Position: 323-341
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: SPAVQPDAALQRLA
Position: 326-339
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: SPAVQPDAALQRLAAV
Position: 326-341
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: SPAVQPDAALQRLAA
Position: 326-340
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 340 341

Chemical type: Peptide from protein
Sequence: SPAVQPDAALQRLAA
Position: 326-340
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 64500.0

Chemical type: Peptide from protein
Sequence: SPAVQPDAALQRLAA
Position: 326-340
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 400.0

Chemical type: Peptide from protein
Sequence: SPLGQSQPTVAGQPSARPAAEEYGYIVTDQKPLSLAAGVK
Position: 449-488
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: SPLGQSQPTVAGQPSARPAAEEYGYIVTDQKPLSLAAGVK
Position: 449-488
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  child
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: SPLGQSQPTVAGQPSARPAAEEYGYIVTDQKPLSLAAGVK
Position: 449-488
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: SPLGQSQPTVAGQPSARPAAEEYGYIVTDQKPLSLAAGVK
Position: 449-488
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  child
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: SPLGQSQPTVAGQPSARPAAEEYGYIVTDQKPLSLAAGVK
Position: 449-488
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: GQPSARPAAEEYGYIVTDQKPLS
Position: 460-482
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: GQPSARPAAEEYGYIVTDQKPLSLAAG
Position: 460-486
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: GQPSARPAAEEYGYIVTDQKPLSLAAGV
Position: 460-487
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: GQPSARPAAEEYGYIVTDQKPLSLAAGVK
Position: 460-488
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: AEEYGYIVTDQKPLSLAAG
Position: 468-486
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: EEYGYIVTDQKPLSLAA
Position: 469-485
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: EEYGYIVTDQKPLSLAAG
Position: 469-486
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: EYGYIVTDQKPLSL
Position: 470-483
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: EYGYIVTDQKPLSLAAG
Position: 470-486
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: EYGYIVTDQKPLSLAAG
Position: 470-486
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 54700.0

Chemical type: Peptide from protein
Sequence: EYGYIVTDQKPLSLAAG
Position: 470-486
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 300.0

Chemical type: Peptide from protein
Sequence: YGYIVTDQKPLS
Position: 471-482
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 340 341

Chemical type: Peptide from protein
Sequence: YGYIVTDQKPLSL
Position: 471-483
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: YGYIVTDQKPLSLAAG
Position: 471-486
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: GYIVTDQKPLSLAAGVK
Position: 472-488
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: YIVTDQKPLSLAAGVK
Position: 473-488
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: EYGYIVTDQKPLS
Position: 470-482
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 340 341

Chemical type: Peptide from protein
Sequence: EYGYIVTDQKPLSLA
Position: 470-484
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 340 341

Chemical type: Peptide from protein
Sequence: EYGYIVTDQKPLSLAA
Position: 470-485
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 340 341

Chemical type: Peptide from protein
Sequence: YGYIVTDQKPLSLA
Position: 471-484
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: YGYIVTDQKPLSLA
Position: 471-484
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: YGYIVTDQKPLSLAA
Position: 471-485
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 340 341

Chemical type: Peptide from protein
Sequence: GYIVTDQKPLS
Position: 472-482
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 340 341

Chemical type: Peptide from protein
Sequence: GYIVTDQKPLSLAA
Position: 472-485
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 340 341

Chemical type: Peptide from protein
Sequence: YIVTDQKPLSLAA
Position: 473-485
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 340 341

Chemical type: Peptide from protein
Sequence: YIVTDQKPLSLAAG
Position: 473-486
Source molecule (GenBank): NP_002837.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 340 341

Chemical type: Peptide from protein
Sequence: ALPRLIAFTSEHSH
Position: 25-38
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: GMAALPRLIAFTSEHSHFSL
Position: 22-41
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: ALPRLIAFTSEHSHFSL
Position: 25-41
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: PRLIAFTSEHSHFSL
Position: 27-41
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: ALPRLIAFTSEHSHFS
Position: 25-40
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 340 341

Chemical type: Peptide from protein
Sequence: ALPRLIAFTSEHSHFS
Position: 25-40
Source molecule (GenBank): AAB28987.1
Assay category: MhcBinding
Result: Negative

Chemical type: Peptide from protein
Sequence: ALPRLIAFTSEHSHFS
Position: 25-40
Source molecule (GenBank): AAB28987.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 14500.0

Chemical type: Peptide from protein
Sequence: LPRLIAFTSEHSH
Position: 26-38
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: LPRLIAFTSEHSH
Position: 26-38
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: LPRLIAFTSEHSHF
Position: 26-39
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: LPRLIAFTSEHSHF
Position: 26-39
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: LPRLIAFTSEHSHFS
Position: 26-40
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 340 341

Chemical type: Peptide from protein
Sequence: DKVNFFRMVISNPAATHQ
Position: 308-325
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 340 341

Chemical type: Peptide from protein
Sequence: DKVNFFRMVISNPAATHQDI
Position: 308-327
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: KVNFFRMVISNPAATH
Position: 309-324
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: VNFFRMVISNPAA
Position: 310-322
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: VNFFRMVISNPAAT
Position: 310-323
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: VNFFRMVISNPAATH
Position: 310-324
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive

Chemical type: Peptide from protein
Sequence: DKVNFFRMVISNPAATHQD
Position: 308-326
Source molecule (GenBank): AAB28987.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 340 341

Chemical type: Peptide from protein
Sequence: DKVNFFRMVISNPAATHQD
Position: 308-326
Source molecule (GenBank): AAB28987.1
Assay category: MhcBinding
Result: Negative

Chemical type: Peptide from protein
Sequence: DKVNFFRMVISNPAATHQD
Position: 308-326
Source molecule (GenBank): AAB28987.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 23500.0