Reference: T Noelle Lombana; Marissa L Matsumoto; Amy M Berkley; Evangeline Toy; Ryan Cook; Yutian Gan; Changchun Du; Paul Schnier; Wendy Sandoval; Zhengmao Ye; Jill M Schartner; Jeong Kim; Christoph Spiess. "High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies." mAbs (2019).

Epitope: Epitope of 1D5 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, Q103, D104, G105, V106, S107, L108, S109, D111, T112, R141, Y145, H152, S153, T154, P156
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 1D5 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, Q103, D104, G105, V106, S107, L108, S109, D111, T112, R141, Y145, H152, S153, T154, P156
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 1D5 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, Q103, D104, G105, V106, S107, L108, S109, D111, T112, R141, Y145, H152, S153, T154, P156
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.5

Epitope: Epitope of 1D5 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, Q103, D104, G105, V106, S107, L108, S109, D111, T112, R141, Y145, H152, S153, T154, P156
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.486

Epitope: Epitope of 1D5 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, Q103, D104, G105, V106, S107, L108, S109, D111, T112, R141, Y145, H152, S153, T154, P156
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.3

Epitope: Epitope of 1D5 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, Q103, D104, G105, V106, S107, L108, S109, D111, T112, R141, Y145, H152, S153, T154, P156
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.09

Epitope: Epitope of 1D5 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, Q103, D104, G105, V106, S107, L108, S109, D111, T112, R141, Y145, H152, S153, T154, P156
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of 1D5 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, Q103, D104, G105, V106, S107, L108, S109, D111, T112, R141, Y145, H152, S153, T154, P156
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 1D5 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, Q103, D104, G105, V106, S107, L108, S109, D111, T112, R141, Y145, H152, S153, T154, P156
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of 1D5 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, Q103, D104, G105, V106, S107, L108, S109, D111, T112, R141, Y145, H152, S153, T154, P156
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0341

Epitope: Epitope of 1D5 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, Q103, D104, G105, V106, S107, L108, S109, D111, T112, R141, Y145, H152, S153, T154, P156
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 1D5 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, Q103, D104, G105, V106, S107, L108, S109, D111, T112, R141, Y145, H152, S153, T154, P156
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 13A9 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, D104, G105, V106, E139, Q140, R141, F142, T143, Y145, E147, G150, N151, H152, S153, T154, P156, V157, P158, S159
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 13A9 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, D104, G105, V106, E139, Q140, R141, F142, T143, Y145, E147, G150, N151, H152, S153, T154, P156, V157, P158, S159
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of 13A9 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, D104, G105, V106, E139, Q140, R141, F142, T143, Y145, E147, G150, N151, H152, S153, T154, P156, V157, P158, S159
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 13A9 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, D104, G105, V106, E139, Q140, R141, F142, T143, Y145, E147, G150, N151, H152, S153, T154, P156, V157, P158, S159
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 13A9 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, D104, G105, V106, E139, Q140, R141, F142, T143, Y145, E147, G150, N151, H152, S153, T154, P156, V157, P158, S159
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 13A9 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, D104, G105, V106, E139, Q140, R141, F142, T143, Y145, E147, G150, N151, H152, S153, T154, P156, V157, P158, S159
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.55

Epitope: Epitope of 13A9 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, D104, G105, V106, E139, Q140, R141, F142, T143, Y145, E147, G150, N151, H152, S153, T154, P156, V157, P158, S159
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.968

Epitope: Epitope of 13A9 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, D104, G105, V106, E139, Q140, R141, F142, T143, Y145, E147, G150, N151, H152, S153, T154, P156, V157, P158, S159
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.9

Epitope: Epitope of 13A9 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, D104, G105, V106, E139, Q140, R141, F142, T143, Y145, E147, G150, N151, H152, S153, T154, P156, V157, P158, S159
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.499

Epitope: Epitope of 13A9 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, D104, G105, V106, E139, Q140, R141, F142, T143, Y145, E147, G150, N151, H152, S153, T154, P156, V157, P158, S159
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of 13A9 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, D104, G105, V106, E139, Q140, R141, F142, T143, Y145, E147, G150, N151, H152, S153, T154, P156, V157, P158, S159
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 13A9 Fab on MICA*008
Chemical type: Discontinuous protein residues
Discontinuous residues: R102, D104, G105, V106, E139, Q140, R141, F142, T143, Y145, E147, G150, N151, H152, S153, T154, P156, V157, P158, S159
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.1

Epitope: Epitope of 6E1 Fab on MICA*008 (C273S)
Chemical type: Discontinuous protein residues
Discontinuous residues: T86, R88, R95, W115, G116, D117, V118, L119, P120, D121, G122, N123, Q127, T128, W129
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of 6E1 Fab on MICA*008 (C273S)
Chemical type: Discontinuous protein residues
Discontinuous residues: T86, R88, R95, W115, G116, D117, V118, L119, P120, D121, G122, N123, Q127, T128, W129
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of 6E1 Fab on MICA*008 (C273S)
Chemical type: Discontinuous protein residues
Discontinuous residues: T86, R88, R95, W115, G116, D117, V118, L119, P120, D121, G122, N123, Q127, T128, W129
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of 6E1 Fab on MICA*008 (C273S)
Chemical type: Discontinuous protein residues
Discontinuous residues: T86, R88, R95, W115, G116, D117, V118, L119, P120, D121, G122, N123, Q127, T128, W129
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.96

Epitope: Epitope of 6E1 Fab on MICA*008 (C273S)
Chemical type: Discontinuous protein residues
Discontinuous residues: T86, R88, R95, W115, G116, D117, V118, L119, P120, D121, G122, N123, Q127, T128, W129
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 8.42

Epitope: Epitope of 6E1 Fab on MICA*008 (C273S)
Chemical type: Discontinuous protein residues
Discontinuous residues: T86, R88, R95, W115, G116, D117, V118, L119, P120, D121, G122, N123, Q127, T128, W129
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 5.75

Epitope: Epitope of 6E1 Fab on MICA*008 (C273S)
Chemical type: Discontinuous protein residues
Discontinuous residues: T86, R88, R95, W115, G116, D117, V118, L119, P120, D121, G122, N123, Q127, T128, W129
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.05

Epitope: Epitope of 6E1 Fab on MICA*008 (C273S)
Chemical type: Discontinuous protein residues
Discontinuous residues: T86, R88, R95, W115, G116, D117, V118, L119, P120, D121, G122, N123, Q127, T128, W129
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 6.8

Epitope: Epitope of 6E1 Fab on MICA*008 (C273S)
Chemical type: Discontinuous protein residues
Discontinuous residues: T86, R88, R95, W115, G116, D117, V118, L119, P120, D121, G122, N123, Q127, T128, W129
Source molecule (GenBank): NP_001276083.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of mAb hum4D5 on HER2
Chemical type: Discontinuous protein residues
Discontinuous residues: E580, D582, Q583, V585, F595, V597
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of mAb hum2C4 on HER2
Chemical type: Discontinuous protein residues
Discontinuous residues: V308, S310, H318, Q320, K333
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive