Reference: Stephanie J Hanna; Wendy E Powell; Anna E Long; Emma J S Robinson; Joanne Davies; Clare Megson; Alexandra Howell; Taz J Jones; Kristin Ladell; David A Price; Colin M Dayan; Alistair J K Williams; Kathleen M Gillespie; F Susan Wong. "Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8<sup>+</sup> T cells and exhibit a distinct CD95<sup>hi</sup> B cell phenotype." Diabetologia (2020).

Epitope: IAPP
Chemical type: Peptide from protein
Sequence: KLQVFLIVL
Position: 5-13
Source molecule (GenBank): P10997.1
Assay category: TCell
Result: Positive
MHC allele types: 327 57 341 350 336 330 418 331
Host:  18-69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IAPP
Chemical type: Peptide from protein
Sequence: KLQVFLIVL
Position: 5-13
Source molecule (GenBank): P10997.1
Assay category: TCell
Result: Negative
MHC allele types: 350 341 327 336 57 330 333 417 352 418
Host:  18-72 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GAD
Chemical type: Peptide from protein
Sequence: VMNILLQYVV
Position: 114-123
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
MHC allele types: 327 57 341 350 336 330 418 331
Host:  18-69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GAD
Chemical type: Peptide from protein
Sequence: VMNILLQYVV
Position: 114-123
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
MHC allele types: 350 341 327 336 57 330 333 417 352 418
Host:  18-72 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PI
Chemical type: Peptide from protein
Sequence: ALWGPDPAAA
Position: 15-24
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive
MHC allele types: 327 57 341 350 336 330 418 331
Host:  18-69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PI
Chemical type: Peptide from protein
Sequence: ALWGPDPAAA
Position: 15-24
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 350 341 327 336 57 330 333 417 352 418
Host:  18-72 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IGRP
Chemical type: Peptide from protein
Sequence: VLFGLGFAI
Position: 265-273
Source molecule (GenBank): Q9NQR9.1
Assay category: TCell
Result: Negative
MHC allele types: 350 341 327 336 57 330 333 417 352 418
Host:  18-72 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IGRP
Chemical type: Peptide from protein
Sequence: VLFGLGFAI
Position: 265-273
Source molecule (GenBank): Q9NQR9.1
Assay category: TCell
Result: Positive
MHC allele types: 327 57 341 350 336 330 418 331
Host:  18-69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: INS
Chemical type: Peptide from protein
Sequence: HLVEALYLV
Position: 10-18
Source molecule (GenBank): 1XDA_B
Assay category: TCell
Result: Negative
MHC allele types: 350 341 327 336 57 330 333 417 352 418
Host:  18-72 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: INS
Chemical type: Peptide from protein
Sequence: HLVEALYLV
Position: 10-18
Source molecule (GenBank): 1XDA_B
Assay category: TCell
Result: Positive
MHC allele types: 327 57 341 350 336 330 418 331
Host:  18-69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA-2
Chemical type: Peptide from protein
Sequence: MVWESGCTV
Position: 797-805
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 350 341 327 336 57 330 333 417 352 418
Host:  18-72 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA-2
Chemical type: Peptide from protein
Sequence: MVWESGCTV
Position: 797-805
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
MHC allele types: 327 57 341 350 336 330 418 331
Host:  18-69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo