Reference: Katherine A Richards; Francisco A Chaves; Frederick R Krafcik; David J Topham; Christopher A Lazarski; Andrea J Sant. "Direct ex vivo analyses of HLA-DR1 transgenic mice reveal an exceptionally broad pattern of immunodominance in the primary HLA-DR1-restricted CD4 T-cell response to influenza virus hemagglutinin." Journal of virology (2007).

Epitope: HA peptide 1
Chemical type: Peptide from protein
Sequence: MKAKLLVLLCTFTATYAD
Position: 1-18
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 2
Chemical type: Peptide from protein
Sequence: LLCTFTATYADTICIGYH
Position: 8-25
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 3
Chemical type: Peptide from protein
Sequence: TYADTICIGYHANNSTDT
Position: 15-32
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 5
Chemical type: Peptide from protein
Sequence: STDTVDTVLEKNVTVTHS
Position: 29-46
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 6
Chemical type: Peptide from protein
Sequence: VLEKNVTVTHSVNLLEDS
Position: 36-53
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 7
Chemical type: Peptide from protein
Sequence: VTHSVNLLEDSHNGKLCL
Position: 43-60
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 9
Chemical type: Peptide from protein
Sequence: KLCLLKGIAPLQLGNCSV
Position: 57-74
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 10
Chemical type: Peptide from protein
Sequence: IAPLQLGNCSVAGWILGN
Position: 64-81
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 11
Chemical type: Peptide from protein
Sequence: NCSVAGWILGNPECELLI
Position: 71-88
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 13
Chemical type: Peptide from protein
Sequence: ELLISKESWSYIVETPNP
Position: 85-102
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 14
Chemical type: Peptide from protein
Sequence: SWSYIVETPNPENGTCYP
Position: 92-109
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 15
Chemical type: Peptide from protein
Sequence: TPNPENGTCYPGYFADYE
Position: 99-116
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 16
Chemical type: Peptide from protein
Sequence: TCYPGYFADYEELREQLS
Position: 106-123
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 17
Chemical type: Peptide from protein
Sequence: ADYEELREQLSSVSSFER
Position: 113-130
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 18
Chemical type: Peptide from protein
Sequence: EQLSSVSSFERFEIFPKE
Position: 120-137
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 19
Chemical type: Peptide from protein
Sequence: SFERFEIFPKESSWPNHT
Position: 127-144
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 20
Chemical type: Peptide from protein
Sequence: FPKESSWPNHTVTGVSAS
Position: 134-151
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 23
Chemical type: Peptide from protein
Sequence: NGKSSFYRNLLWLTGKNG
Position: 155-172
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive-High
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 24
Chemical type: Peptide from protein
Sequence: RNLLWLTGKNGLYPNLSK
Position: 162-179
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive-High
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 25
Chemical type: Peptide from protein
Sequence: GKNGLYPNLSKSYVNNKE
Position: 169-186
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 27
Chemical type: Peptide from protein
Sequence: NNKEKEVLVLWGVHHPPN
Position: 183-200
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 28
Chemical type: Peptide from protein
Sequence: LVLWGVHHPPNIGNQRAL
Position: 190-207
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 29
Chemical type: Peptide from protein
Sequence: HPPNIGNQRALYHTENAY
Position: 197-214
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 32
Chemical type: Peptide from protein
Sequence: VSSHYSRRFTPEIAKRPK
Position: 218-235
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 33
Chemical type: Peptide from protein
Sequence: RFTPEIAKRPKVRDQEGR
Position: 225-242
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 34
Chemical type: Peptide from protein
Sequence: KRPKVRDQEGRINYYWTL
Position: 232-249
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 36
Chemical type: Peptide from protein
Sequence: YWTLLEPGDTIIFEANGN
Position: 246-263
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 37
Chemical type: Peptide from protein
Sequence: GDTIIFEANGNLIAPWYA
Position: 253-270
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive-High
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 38
Chemical type: Peptide from protein
Sequence: ANGNLIAPWYAFALSRGF
Position: 260-277
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 40
Chemical type: Peptide from protein
Sequence: SRGFGSGIITSNAPMDEC
Position: 274-291
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 41
Chemical type: Peptide from protein
Sequence: IITSNAPMDECDAKCQTP
Position: 281-298
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 42
Chemical type: Peptide from protein
Sequence: MDECDAKCQTPQGAINSS
Position: 288-305
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 43
Chemical type: Peptide from protein
Sequence: CQTPQGAINSSLPFQNVH
Position: 295-312
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 44
Chemical type: Peptide from protein
Sequence: INSSLPFQNVHPVTIGEC
Position: 302-319
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 45
Chemical type: Peptide from protein
Sequence: QNVHPVTIGECPKYVRSA
Position: 309-326
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 47
Chemical type: Peptide from protein
Sequence: VRSAKLRMVTGLRNIPSI
Position: 323-340
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 51
Chemical type: Peptide from protein
Sequence: GFIEGGWTGMVDGWYGYH
Position: 351-368
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 52
Chemical type: Peptide from protein
Sequence: TGMVDGWYGYHHQNEQGS
Position: 358-375
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 54
Chemical type: Peptide from protein
Sequence: EQGSGYAADQKSTQNAIN
Position: 372-389
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 55
Chemical type: Peptide from protein
Sequence: ADQKSTQNAINGITNKVN
Position: 379-396
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 57
Chemical type: Peptide from protein
Sequence: NKVNSVIEKMNTQFTAVG
Position: 393-410
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 60
Chemical type: Peptide from protein
Sequence: NKLERRMENLNKKVDDGF
Position: 414-431
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 61
Chemical type: Peptide from protein
Sequence: ENLNKKVDDGFLDIWTYN
Position: 421-438
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 63
Chemical type: Peptide from protein
Sequence: WTYNAELLVLLENERTLD
Position: 435-452
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive-High
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 65
Chemical type: Peptide from protein
Sequence: RTLDFHDSNVKNLYEKVK
Position: 449-466
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 67
Chemical type: Peptide from protein
Sequence: EKVKSQLKNNAKEIGNGC
Position: 463-480
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 69
Chemical type: Peptide from protein
Sequence: GNGCFEFYHKCNNECMES
Position: 477-494
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 70
Chemical type: Peptide from protein
Sequence: YHKCNNECMESVKNGTYD
Position: 484-501
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 73
Chemical type: Peptide from protein
Sequence: YSEESKLNREKIDGVKLE
Position: 505-522
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 76
Chemical type: Peptide from protein
Sequence: VYQILAIYSTVASSLVLL
Position: 526-543
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 77
Chemical type: Peptide from protein
Sequence: YSTVASSLVLLVSLGAIS
Position: 533-550
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HA peptide 80
Chemical type: Peptide from protein
Sequence: CSNGSLQCRICI
Position: 554-565
Source molecule (GenBank): AAP34324.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo