Reference: Qin Ouyang; Nathan E Standifer; Huilian Qin; Peter Gottlieb; C Bruce Verchere; Gerald T Nepom; Rusung Tan; Constadina Panagiotopoulos. "Recognition of HLA class I-restricted beta-cell epitopes in type 1 diabetes." Diabetes (2006).

Epitope: Phogrin 893-901
Chemical type: Peptide from protein
Sequence: SLLDFRRKV
Position: 893-901
Source molecule (GenBank): NP_570858.2
Assay category: MhcBinding
Result: Positive

Epitope: Phogrin 387-395
Chemical type: Peptide from protein
Sequence: RLYQEVHRL
Position: 387-395
Source molecule (GenBank): NP_570858.2
Assay category: MhcBinding
Result: Positive

Epitope: Phogrin 335-343
Chemical type: Peptide from protein
Sequence: LMAGLMQGV
Position: 335-343
Source molecule (GenBank): NP_570858.2
Assay category: MhcBinding
Result: Positive

Epitope: Phogrin 331-339
Chemical type: Peptide from protein
Sequence: GMAELMAGL
Position: 331-339
Source molecule (GenBank): NP_570858.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phogrin 331-339
Chemical type: Peptide from protein
Sequence: GMAELMAGL
Position: 331-339
Source molecule (GenBank): NP_570858.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phogrin 331-339
Chemical type: Peptide from protein
Sequence: GMAELMAGL
Position: 331-339
Source molecule (GenBank): NP_570858.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phogrin 11-19
Chemical type: Peptide from protein
Sequence: LLLLLPPRV
Position: 11-19
Source molecule (GenBank): NP_570858.2
Assay category: MhcBinding
Result: Positive

Epitope: Phogrin 7-15
Chemical type: Peptide from protein
Sequence: LLLLLLLLL
Position: 7-15
Source molecule (GenBank): NP_570858.2
Assay category: MhcBinding
Result: Positive-Low

Epitope: IA-2 577-585
Chemical type: Peptide from protein
Sequence: VLLTLVALA
Position: 577-585
Source molecule (GenBank): Q16849.1
Assay category: MhcBinding
Result: Positive

Epitope: IA-2 359-367
Chemical type: Peptide from protein
Sequence: TLLTLLQLL
Position: 359-367
Source molecule (GenBank): Q16849.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: IA-2 341-349
Chemical type: Peptide from protein
Sequence: VLAGYGVEL
Position: 341-349
Source molecule (GenBank): Q16849.1
Assay category: MhcBinding
Result: Positive-High

Epitope: IA-2 277-285
Chemical type: Peptide from protein
Sequence: GLLYLAQEL
Position: 277-285
Source molecule (GenBank): Q16849.1
Assay category: MhcBinding
Result: Positive-High

Epitope: IA-2 180-188
Chemical type: Peptide from protein
Sequence: LLPPLLEHL
Position: 180-188
Source molecule (GenBank): Q16849.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA-2 180-188
Chemical type: Peptide from protein
Sequence: LLPPLLEHL
Position: 180-188
Source molecule (GenBank): Q16849.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA-2 180-188
Chemical type: Peptide from protein
Sequence: LLPPLLEHL
Position: 180-188
Source molecule (GenBank): Q16849.1
Assay category: MhcBinding
Result: Positive-High

Epitope: IA-2 172-180
Chemical type: Peptide from protein
Sequence: SLSPLQAEL
Position: 172-180
Source molecule (GenBank): Q16849.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA-2 172-180
Chemical type: Peptide from protein
Sequence: SLSPLQAEL
Position: 172-180
Source molecule (GenBank): Q16849.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA-2 172-180
Chemical type: Peptide from protein
Sequence: SLSPLQAEL
Position: 172-180
Source molecule (GenBank): Q16849.1
Assay category: MhcBinding
Result: Positive-High

Epitope: Insulin C6-C14
Chemical type: Peptide from protein
Sequence: DLQVGQVEL
Position: 60-68
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: Insulin B10-B18
Chemical type: Peptide from protein
Sequence: HLVEALYLV
Position: 34-42
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Insulin B10-B18
Chemical type: Peptide from protein
Sequence: HLVEALYLV
Position: 34-42
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Insulin B10-B18
Chemical type: Peptide from protein
Sequence: HLVEALYLV
Position: 34-42
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Positive-High

Epitope: Insulin 2-10
Chemical type: Peptide from protein
Sequence: ALWMRLLPL
Position: 2-10
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Insulin 2-10
Chemical type: Peptide from protein
Sequence: ALWMRLLPL
Position: 2-10
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Insulin 2-10
Chemical type: Peptide from protein
Sequence: ALWMRLLPL
Position: 2-10
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Positive-High

Epitope: IGRP 215-223
Chemical type: Peptide from protein
Sequence: FLFAVGFYL
Position: 215-223
Source molecule (GenBank): NP_066999.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IGRP 215-223
Chemical type: Peptide from protein
Sequence: FLFAVGFYL
Position: 215-223
Source molecule (GenBank): NP_066999.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IGRP 215-223
Chemical type: Peptide from protein
Sequence: FLFAVGFYL
Position: 215-223
Source molecule (GenBank): NP_066999.1
Assay category: MhcBinding
Result: Positive-High

Epitope: IGRP 152-160
Chemical type: Peptide from protein
Sequence: FLWSVFMLI
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IGRP 152-160
Chemical type: Peptide from protein
Sequence: FLWSVFMLI
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IGRP 152-160
Chemical type: Peptide from protein
Sequence: FLWSVFMLI
Assay category: MhcBinding
Result: Positive

Epitope: IAPP 9-17
Chemical type: Peptide from protein
Sequence: FLIVLSVAL
Position: 9-17
Source molecule (GenBank): P10997.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IAPP 9-17
Chemical type: Peptide from protein
Sequence: FLIVLSVAL
Position: 9-17
Source molecule (GenBank): P10997.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IAPP 9-17
Chemical type: Peptide from protein
Sequence: FLIVLSVAL
Position: 9-17
Source molecule (GenBank): P10997.1
Assay category: MhcBinding
Result: Positive

Epitope: IAPP 5-13
Chemical type: Peptide from protein
Sequence: KLQVFLIVL
Position: 5-13
Source molecule (GenBank): P10997.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IAPP 5-13
Chemical type: Peptide from protein
Sequence: KLQVFLIVL
Position: 5-13
Source molecule (GenBank): P10997.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IAPP 5-13
Chemical type: Peptide from protein
Sequence: KLQVFLIVL
Position: 5-13
Source molecule (GenBank): P10997.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: EBV BZLF1
Chemical type: Peptide from protein
Sequence: RAKFKQLL
Position: 190-197
Source molecule (GenBank): P03206.2
Assay category: MhcBinding
Result: Negative

Epitope: CMV
Chemical type: Peptide from protein
Sequence: NLVPMVATV
Position: 495-503
Source molecule (GenBank): P06725.2
Assay category: MhcBinding
Result: Positive-High