Reference: René Bartz; Keisuke Fukuchi; Toshiaki Ohtsuka; Tanja Lange; Katrin Gruner; Ichiro Watanabe; Shinko Hayashi; Yoko Oda; Reimi Kawaida; Hironobu Komori; Yoshinori Kashimoto; Peter Wirtz; Jan-Peter A Mayer; Mauricio Redondo-Müller; Shuntaro Saito; Mizuki Takahashi; Hiroyuki Hanzawa; Emi Imai; Alberto Martinez; Masaharu Hanai; Dieter Häussinger; Roger W Chapman; Toshinori Agatsuma; Johannes Bange; Reimar Abraham. "Preclinical Development of U3-1784, a Novel FGFR4 Antibody Against Cancer, and Avoidance of Its On-target Toxicity." Molecular cancer therapeutics (2019).

Epitope: Epitope of U3-1784 Fab on FGFR4
Chemical type: Discontinuous protein residues
Discontinuous residues: W149, E156, K157, K158, L159, A161, G220, T221, R234, Y235, N236, L238, L239, D240, V241, L242
Source molecule (GenBank): P22455.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.36

Epitope: Epitope of U3-1784 Fab on FGFR4
Chemical type: Discontinuous protein residues
Discontinuous residues: W149, E156, K157, K158, L159, A161, G220, T221, R234, Y235, N236, L238, L239, D240, V241, L242
Source molecule (GenBank): P22455.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.41

Epitope: Epitope of U3-1784 Fab on FGFR4
Chemical type: Discontinuous protein residues
Discontinuous residues: W149, E156, K157, K158, L159, A161, G220, T221, R234, Y235, N236, L238, L239, D240, V241, L242
Source molecule (GenBank): P22455.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.44

Epitope: Epitope of U3-1784 Fab on FGFR4
Chemical type: Discontinuous protein residues
Discontinuous residues: W149, E156, K157, K158, L159, A161, G220, T221, R234, Y235, N236, L238, L239, D240, V241, L242
Source molecule (GenBank): P22455.2
Assay category: BCell
Result: Positive

Epitope: Epitope of U3-1784 Fab on FGFR4
Chemical type: Discontinuous protein residues
Discontinuous residues: W149, E156, K157, K158, L159, A161, G220, T221, R234, Y235, N236, L238, L239, D240, V241, L242
Source molecule (GenBank): P22455.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2.15

Epitope: Epitope of U3-1784 Fab on FGFR4
Chemical type: Discontinuous protein residues
Discontinuous residues: W149, E156, K157, K158, L159, A161, G220, T221, R234, Y235, N236, L238, L239, D240, V241, L242
Source molecule (GenBank): P22455.2
Assay category: BCell
Result: Positive

Epitope: Epitope of U3-1784 Fab on FGFR4
Chemical type: Discontinuous protein residues
Discontinuous residues: W149, E156, K157, K158, L159, A161, G220, T221, R234, Y235, N236, L238, L239, D240, V241, L242
Source molecule (GenBank): P22455.2
Assay category: BCell
Result: Positive

Epitope: Epitope of U3-1784 Fab on FGFR4
Chemical type: Discontinuous protein residues
Discontinuous residues: W149, E156, K157, K158, L159, A161, G220, T221, R234, Y235, N236, L238, L239, D240, V241, L242
Source molecule (GenBank): P22455.2
Assay category: BCell
Result: Positive

Epitope: Epitope of U3-1784 Fab on FGFR4
Chemical type: Discontinuous protein residues
Discontinuous residues: W149, E156, K157, K158, L159, A161, G220, T221, R234, Y235, N236, L238, L239, D240, V241, L242
Source molecule (GenBank): P22455.2
Assay category: BCell
Result: Positive

Epitope: Epitope of U3-1784 Fab on FGFR4
Chemical type: Discontinuous protein residues
Discontinuous residues: W149, E156, K157, K158, L159, A161, G220, T221, R234, Y235, N236, L238, L239, D240, V241, L242
Source molecule (GenBank): P22455.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.36