Reference: Yi Li; Lina Zhou; Yashu Li; Jie Zhang; Binbin Guo; Gang Meng; Xiaoling Chen; Qian Zheng; Linlin Zhang; Mengjun Zhang; Li Wang. "Identification of autoreactive CD8+ T cell responses targeting chromogranin A in humanized NOD mice and type 1 diabetes patients." Clinical immunology (Orlando, Fla.) (2015).

Epitope: mChgA 8–16
Chemical type: Peptide from protein
Sequence: ALLLCAGQV
Position: 8-16
Source molecule (GenBank): P26339.1
Assay category: TCell
Result: Negative
Host: F 12-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mChgA 8–16
Chemical type: Peptide from protein
Sequence: ALLLCAGQV
Position: 8-16
Source molecule (GenBank): P26339.1
Assay category: TCell
Result: Negative
Host: F 12-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mChgA 8–16
Chemical type: Peptide from protein
Sequence: ALLLCAGQV
Position: 8-16
Source molecule (GenBank): P26339.1
Assay category: MhcBinding
Result: Negative

Epitope: hChgA 8–16
Chemical type: Peptide from protein
Sequence: ALLLCAGQV
Position: 8-16
Source molecule (GenBank): P10645.7
Assay category: MhcBinding
Result: Negative

Epitope: mChgA 10–19
Chemical type: Peptide from protein
Sequence: LLCAGQVFAL
Position: 10-19
Source molecule (GenBank): P26339.1
Assay category: TCell
Result: Positive
Host: F 12-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mChgA 10–19
Chemical type: Peptide from protein
Sequence: LLCAGQVFAL
Position: 10-19
Source molecule (GenBank): P26339.1
Assay category: TCell
Result: Positive
Host: F 12-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mChgA 10–19
Chemical type: Peptide from protein
Sequence: LLCAGQVFAL
Position: 10-19
Source molecule (GenBank): P26339.1
Assay category: TCell
Result: Positive
Host: F 12-16 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mChgA 10–19
Chemical type: Peptide from protein
Sequence: LLCAGQVFAL
Position: 10-19
Source molecule (GenBank): P26339.1
Assay category: TCell
Result: Positive
Host: F 12-16 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mChgA 10–19
Chemical type: Peptide from protein
Sequence: LLCAGQVFAL
Position: 10-19
Source molecule (GenBank): P26339.1
Assay category: TCell
Result: Positive
Host: F 12-16 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mChgA 10–19
Chemical type: Peptide from protein
Sequence: LLCAGQVFAL
Position: 10-19
Source molecule (GenBank): P26339.1
Assay category: MhcBinding
Result: Positive

Epitope: hChgA 10–19
Chemical type: Peptide from protein
Sequence: LLCAGQVTAL
Position: 10-19
Source molecule (GenBank): P10645.7
Assay category: TCell
Result: Positive
Host:  5-14 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: hChgA 10–19
Chemical type: Peptide from protein
Sequence: LLCAGQVTAL
Position: 10-19
Source molecule (GenBank): P10645.7
Assay category: MhcBinding
Result: Positive

Epitope: mChgA 43–52
Chemical type: Peptide from protein
Sequence: SLSKPSPMPV
Position: 43-52
Source molecule (GenBank): P26339.1
Assay category: TCell
Result: Positive
Host: F 12-16 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mChgA 43–52
Chemical type: Peptide from protein
Sequence: SLSKPSPMPV
Position: 43-52
Source molecule (GenBank): P26339.1
Assay category: TCell
Result: Positive
Host: F 12-16 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mChgA 43–52
Chemical type: Peptide from protein
Sequence: SLSKPSPMPV
Position: 43-52
Source molecule (GenBank): P26339.1
Assay category: TCell
Result: Positive
Host: F 12-16 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mChgA 43–52
Chemical type: Peptide from protein
Sequence: SLSKPSPMPV
Position: 43-52
Source molecule (GenBank): P26339.1
Assay category: TCell
Result: Positive
Host: F 12-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mChgA 43–52
Chemical type: Peptide from protein
Sequence: SLSKPSPMPV
Position: 43-52
Source molecule (GenBank): P26339.1
Assay category: TCell
Result: Positive
Host: F 12-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mChgA 43–52
Chemical type: Peptide from protein
Sequence: SLSKPSPMPV
Position: 43-52
Source molecule (GenBank): P26339.1
Assay category: MhcBinding
Result: Positive

Epitope: hChgA 43–52
Chemical type: Peptide from protein
Sequence: TLSKPSPMPV
Position: 43-52
Source molecule (GenBank): P10645.7
Assay category: TCell
Result: Positive
Host:  5-14 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: hChgA 43–52
Chemical type: Peptide from protein
Sequence: TLSKPSPMPV
Position: 43-52
Source molecule (GenBank): P10645.7
Assay category: MhcBinding
Result: Positive

Epitope: mChgA 75–84
Chemical type: Peptide from protein
Sequence: LLKELQDLAL
Position: 75-84
Source molecule (GenBank): P26339.1
Assay category: TCell
Result: Negative
Host: F 12-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mChgA 75–84
Chemical type: Peptide from protein
Sequence: LLKELQDLAL
Position: 75-84
Source molecule (GenBank): P26339.1
Assay category: TCell
Result: Negative
Host: F 12-16 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mChgA 75–84
Chemical type: Peptide from protein
Sequence: LLKELQDLAL
Position: 75-84
Source molecule (GenBank): P26339.1
Assay category: MhcBinding
Result: Negative

Epitope: hChgA 75–84
Chemical type: Peptide from protein
Sequence: LLKELQDLAL
Position: 75-84
Source molecule (GenBank): P10645.7
Assay category: MhcBinding
Result: Negative

Epitope: IGRP 206–214
Chemical type: Peptide from protein
Sequence: VYLKTNVFL
Position: 206-214
Source molecule (GenBank): Q9Z186.1
Assay category: MhcBinding
Result: Negative

Epitope: HIV Pol 476–484
Chemical type: Peptide from protein
Sequence: ILKEPVHGV
Position: 471-479
Source molecule (GenBank): ADZ56462.1
Assay category: MhcBinding
Result: Positive

Epitope: IGRP 265-273
Chemical type: Peptide from protein
Sequence: VLFGLGFAI
Position: 265-273
Source molecule (GenBank): Q9Z186.1
Assay category: TCell
Result: Positive
Host:  5-14 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo