Reference: S Veeraraghavan; E A Renzoni; H Jeal; M Jones; J Hammer; A U Wells; C M Black; K I Welsh; R M du Bois. "Mapping of the immunodominant T cell epitopes of the protein topoisomerase I." Annals of the rheumatic diseases (2004).

Epitope: Peptide 1
Chemical type: Peptide from protein
Sequence: SQIEADFRLNDSHKHKD
Position: 10-26
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Negative
Host:  33-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 1
Chemical type: Peptide from protein
Sequence: SQIEADFRLNDSHKHKD
Position: 10-26
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Negative
Host:  24-39 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 2
Chemical type: Peptide from protein
Sequence: HPKMGMLKRRIMPED
Position: 367-381
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  24-39 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 2
Chemical type: Peptide from protein
Sequence: HPKMGMLKRRIMPED
Position: 367-381
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  33-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 3
Chemical type: Peptide from protein
Sequence: LKRRIMPEDIIINCS
Position: 373-387
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Negative
Host:  24-39 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 3
Chemical type: Peptide from protein
Sequence: LKRRIMPEDIIINCS
Position: 373-387
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  33-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 3
Chemical type: Peptide from protein
Sequence: LKRRIMPEDIIINCS
Position: 373-387
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  24-39 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 3
Chemical type: Peptide from protein
Sequence: LKRRIMPEDIIINCS
Position: 373-387
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  24-39 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 3
Chemical type: Peptide from protein
Sequence: LKRRIMPEDIIINCS
Position: 373-387
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  24-39 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 3
Chemical type: Peptide from protein
Sequence: LKRRIMPEDIIINCS
Position: 373-387
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  33-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 3
Chemical type: Peptide from protein
Sequence: LKRRIMPEDIIINCS
Position: 373-387
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  33-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 3
Chemical type: Peptide from protein
Sequence: LKRRIMPEDIIINCS
Position: 373-387
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  33-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 4
Chemical type: Peptide from protein
Sequence: PEDIIINCSKDAKVP
Position: 379-393
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  24-39 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 4
Chemical type: Peptide from protein
Sequence: PEDIIINCSKDAKVP
Position: 379-393
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  33-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 5
Chemical type: Peptide from protein
Sequence: AKVFRTYNASITLQQQL
Position: 586-602
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  24-39 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 5
Chemical type: Peptide from protein
Sequence: AKVFRTYNASITLQQQL
Position: 586-602
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  33-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 5
Chemical type: Peptide from protein
Sequence: AKVFRTYNASITLQQQL
Position: 586-602
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  33-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 5
Chemical type: Peptide from protein
Sequence: AKVFRTYNASITLQQQL
Position: 586-602
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  33-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 5
Chemical type: Peptide from protein
Sequence: AKVFRTYNASITLQQQL
Position: 586-602
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  24-39 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 5
Chemical type: Peptide from protein
Sequence: AKVFRTYNASITLQQQL
Position: 586-602
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  24-39 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 6
Chemical type: Peptide from protein
Sequence: EKSMMNLQTKIDAKKE
Position: 641-656
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Negative
Host:  24-39 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 6
Chemical type: Peptide from protein
Sequence: EKSMMNLQTKIDAKKE
Position: 641-656
Source molecule (GenBank): P11387.2
Assay category: TCell
Result: Positive
Host:  33-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo