Reference: S Pruksakorn; B Currie; E Brandt; C Phornphutkul; S Hunsakunachai; A Manmontri; J H Robinson; M A Kehoe; A Galbraith; M F Good. "Identification of T cell autoepitopes that cross-react with the C-terminal segment of the M protein of group A streptococci." International immunology (1994).

Epitope: 145
Chemical type: Peptide from protein
Sequence: LRRDLDASREAKKQVEKALE
Position: 337-356
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 145
Chemical type: Peptide from protein
Sequence: LRRDLDASREAKKQVEKALE
Position: 337-356
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Quantitative measurement: 430.0
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: 145
Chemical type: Peptide from protein
Sequence: LRRDLDASREAKKQVEKALE
Position: 337-356
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 145
Chemical type: Peptide from protein
Sequence: LRRDLDASREAKKQVEKALE
Position: 337-356
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 147
Chemical type: Peptide from protein
Sequence: EANSKLAALEKLNKELEESK
Position: 357-376
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 148
Chemical type: Peptide from protein
Sequence: KLNKELEESKKLTEKEKAEL
Position: 367-386
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 149
Chemical type: Peptide from protein
Sequence: KLTEKEKAELQAKLEAEAKA
Position: 377-396
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 149
Chemical type: Peptide from protein
Sequence: KLTEKEKAELQAKLEAEAKA
Position: 377-396
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 149
Chemical type: Peptide from protein
Sequence: KLTEKEKAELQAKLEAEAKA
Position: 377-396
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 150
Chemical type: Peptide from protein
Sequence: QAKLEAEAKALKEQLAKQAE
Position: 387-406
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 150
Chemical type: Peptide from protein
Sequence: QAKLEAEAKALKEQLAKQAE
Position: 387-406
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 150
Chemical type: Peptide from protein
Sequence: QAKLEAEAKALKEQLAKQAE
Position: 387-406
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 150
Chemical type: Peptide from protein
Sequence: QAKLEAEAKALKEQLAKQAE
Position: 387-406
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 151
Chemical type: Peptide from protein
Sequence: LKEQLAKQAEELAKLRAGKA
Position: 397-416
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 151
Chemical type: Peptide from protein
Sequence: LKEQLAKQAEELAKLRAGKA
Position: 397-416
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Quantitative measurement: 46.0
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: 151
Chemical type: Peptide from protein
Sequence: LKEQLAKQAEELAKLRAGKA
Position: 397-416
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 151
Chemical type: Peptide from protein
Sequence: LKEQLAKQAEELAKLRAGKA
Position: 397-416
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 151
Chemical type: Peptide from protein
Sequence: LKEQLAKQAEELAKLRAGKA
Position: 397-416
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 151
Chemical type: Peptide from protein
Sequence: LKEQLAKQAEELAKLRAGKA
Position: 397-416
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 152
Chemical type: Peptide from protein
Sequence: ELAKLRAGKASDSQTPDTKP
Position: 407-426
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 152
Chemical type: Peptide from protein
Sequence: ELAKLRAGKASDSQTPDTKP
Position: 407-426
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 152
Chemical type: Peptide from protein
Sequence: ELAKLRAGKASDSQTPDTKP
Position: 407-426
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 152
Chemical type: Peptide from protein
Sequence: ELAKLRAGKASDSQTPDTKP
Position: 407-426
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 152
Chemical type: Peptide from protein
Sequence: ELAKLRAGKASDSQTPDTKP
Position: 407-426
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 153
Chemical type: Peptide from protein
Sequence: SDSQTPDTKPGNKAVPGKGQ
Position: 417-436
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 154
Chemical type: Peptide from protein
Sequence: GNKAVPGKGQAPQAGTKPNQ
Position: 427-446
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 155
Chemical type: Peptide from protein
Sequence: APQAGTKPNQNKAPMKETKR
Position: 437-456
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 156
Chemical type: Peptide from protein
Sequence: NKAPMKETKRQLPSTGETAN
Position: 447-466
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 157
Chemical type: Peptide from protein
Sequence: QLPSTGETANPFFTAAALTV
Position: 457-476
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 157
Chemical type: Peptide from protein
Sequence: QLPSTGETANPFFTAAALTV
Position: 457-476
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 157
Chemical type: Peptide from protein
Sequence: QLPSTGETANPFFTAAALTV
Position: 457-476
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 157
Chemical type: Peptide from protein
Sequence: QLPSTGETANPFFTAAALTV
Position: 457-476
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 158
Chemical type: Peptide from protein
Sequence: PFFTAAALTVMATAGVAAVV
Position: 467-486
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 158
Chemical type: Peptide from protein
Sequence: PFFTAAALTVMATAGVAAVV
Position: 467-486
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 158
Chemical type: Peptide from protein
Sequence: PFFTAAALTVMATAGVAAVV
Position: 467-486
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 158
Chemical type: Peptide from protein
Sequence: PFFTAAALTVMATAGVAAVV
Position: 467-486
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 159
Chemical type: Peptide from protein
Sequence: MATAGVAAVVKRKEEN
Position: 477-492
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 160
Chemical type: Peptide from protein
Sequence: AVTRGTINDPQRAKEALDYE
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 160
Chemical type: Peptide from protein
Sequence: AVTRGTINDPQRAKEALDYE
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 160
Chemical type: Peptide from protein
Sequence: AVTRGTINDPQRAKEALDYE
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 160
Chemical type: Peptide from protein
Sequence: AVTRGTINDPQRAKEALDYE
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 162
Chemical type: Peptide from protein
Sequence: VATRSQTDTLEKVQERADKF
Position: 43-62
Source molecule (GenBank): P12379.1
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 164
Chemical type: Peptide from protein
Sequence: ALRSQEDLKEQLAMVERRAN
Position: 1666-1685
Source molecule (GenBank): Q9UKX2.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 164
Chemical type: Peptide from protein
Sequence: ALRSQEDLKEQLAMVERRAN
Position: 1666-1685
Source molecule (GenBank): Q9UKX2.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: 168
Chemical type: Peptide from protein
Sequence: KKQVEQEKSELQAALEEAEA
Position: 1534-1553
Source molecule (GenBank): NP_005954.3
Assay category: TCell
Result: Positive
Quantitative measurement: 10.0
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: 169
Chemical type: Peptide from protein
Sequence: LRRDIDDLELTLAKVEKEKH
Assay category: TCell
Result: Positive
Quantitative measurement: 261.0
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: 169
Chemical type: Peptide from protein
Sequence: LRRDIDDLELTLAKVEKEKH
Assay category: TCell
Result: Positive
Quantitative measurement: 7.1
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: 170
Chemical type: Peptide from protein
Sequence: LRMDLERAKRKLEGDLKLAQ
Position: 1047-1066
Source molecule (GenBank): P13535.3
Assay category: TCell
Result: Positive
Quantitative measurement: 82.0
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: 170
Chemical type: Peptide from protein
Sequence: LRMDLERAKRKLEGDLKLAQ
Position: 1047-1066
Source molecule (GenBank): P13535.3
Assay category: TCell
Result: Positive
Quantitative measurement: 4.9
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: 173
Chemical type: Peptide from protein
Sequence: KRQAEEAEEQANTNLSKFR
Position: 1879-1897
Source molecule (GenBank): P12883.5
Assay category: TCell
Result: Positive
Quantitative measurement: 27.0
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: 173
Chemical type: Peptide from protein
Sequence: KRQAEEAEEQANTNLSKFR
Position: 1879-1897
Source molecule (GenBank): P12883.5
Assay category: TCell
Result: Positive
Quantitative measurement: 5.4
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: 161
Chemical type: Peptide, no natural source
Sequence: RVFPRGTVENPDKARELNKY
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: blood
Culture conditions: Direct Ex Vivo