Reference: T Lohmann; T Halder; J Engler; N G Morgenthaler; U Y Khoo-Morgenthaler; S Schröder; J Seissler; W A Scherbaum; H Kalbacher. "T cell reactivity to DR*0401- and DQ*0302-binding peptides of the putative autoantigen IA-2 in type 1 diabetes." Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association (1999).

Epitope: IA2 95-107
Chemical type: Peptide from protein
Sequence: LSWHDDLTQYVIS
Position: 95-107
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  17-56
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 95-107
Chemical type: Peptide from protein
Sequence: LSWHDDLTQYVIS
Position: 95-107
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Positive
Host:  24-36
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 546-560
Chemical type: Peptide from protein
Sequence: GLQILQTGVGQREE
Position: 546-559
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  17-56
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 546-560
Chemical type: Peptide from protein
Sequence: GLQILQTGVGQREE
Position: 546-559
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  24-36
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 711-725
Chemical type: Peptide from protein
Sequence: KEWQALCAYQAEPNT
Position: 711-725
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  17-56
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 711-725
Chemical type: Peptide from protein
Sequence: KEWQALCAYQAEPNT
Position: 711-725
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  24-36
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 797-809
Chemical type: Peptide from protein
Sequence: MVWESGCTVIVML
Position: 797-809
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Positive
Host:  17-56
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 797-809
Chemical type: Peptide from protein
Sequence: MVWESGCTVIVML
Position: 797-809
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Positive
Host:  24-36
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 797-809
Chemical type: Peptide from protein
Sequence: MVWESGCTVIVML
Position: 797-809
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Positive
Host:  17-56
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 797-809
Chemical type: Peptide from protein
Sequence: MVWESGCTVIVML
Position: 797-809
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Positive
Host:  24-36
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 797-809
Chemical type: Peptide from protein
Sequence: MVWESGCTVIVML
Position: 797-809
Source molecule (GenBank): AAA90974.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: IA2 797-809
Chemical type: Peptide from protein
Sequence: MVWESGCTVIVML
Position: 797-809
Source molecule (GenBank): AAA90974.1
Assay category: MhcBinding
Result: Positive-High

Epitope: IA2 854-866
Chemical type: Peptide from protein
Sequence: FYLKNVQTQETRT
Position: 854-866
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Positive
Host:  17-56
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 854-866
Chemical type: Peptide from protein
Sequence: FYLKNVQTQETRT
Position: 854-866
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  24-36
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 854-866
Chemical type: Peptide from protein
Sequence: FYLKNVQTQETRT
Position: 854-866
Source molecule (GenBank): AAA90974.1
Assay category: MhcBinding
Result: Positive-High

Epitope: IA2 854-866
Chemical type: Peptide from protein
Sequence: FYLKNVQTQETRT
Position: 854-866
Source molecule (GenBank): AAA90974.1
Assay category: MhcBinding
Result: Positive-High

Epitope: IA2 873-885
Chemical type: Peptide from protein
Sequence: LSWPAEGTPASTR
Position: 873-885
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  17-56
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 873-885
Chemical type: Peptide from protein
Sequence: LSWPAEGTPASTR
Position: 873-885
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  24-36
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 608-620
Chemical type: Peptide from protein
Sequence: DKERLAALGPEGA
Position: 608-620
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Positive
Host:  17-56
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 608-620
Chemical type: Peptide from protein
Sequence: DKERLAALGPEGA
Position: 608-620
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  24-36
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 741-753
Chemical type: Peptide from protein
Sequence: YDHARIKLKVESS
Position: 746-758
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  17-56
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 741-753
Chemical type: Peptide from protein
Sequence: YDHARIKLKVESS
Position: 746-758
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  24-36
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 762-774
Chemical type: Peptide from protein
Sequence: SDYINASPIIEHD
Position: 762-774
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  17-56
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 762-774
Chemical type: Peptide from protein
Sequence: SDYINASPIIEHD
Position: 762-774
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Positive
Host:  24-36
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 803-815
Chemical type: Peptide from protein
Sequence: TVIVMLTPLVEDG
Position: 804-816
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Positive
Host:  17-56
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 803-815
Chemical type: Peptide from protein
Sequence: TVIVMLTPLVEDG
Position: 804-816
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Positive
Host:  24-36
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 832-844
Chemical type: Peptide from protein
Sequence: YHVYEVNLVSEHI
Position: 832-844
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  17-56
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 832-844
Chemical type: Peptide from protein
Sequence: YHVYEVNLVSEHI
Position: 832-844
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  24-36
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 925-937
Chemical type: Peptide from protein
Sequence: VLNRMAKGVKEID
Position: 925-937
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  17-56
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 925-937
Chemical type: Peptide from protein
Sequence: VLNRMAKGVKEID
Position: 925-937
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Positive
Host:  24-36
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 933-945
Chemical type: Peptide from protein
Sequence: VKEIDIAATLEHV
Position: 933-945
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Positive
Host:  17-56
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 933-945
Chemical type: Peptide from protein
Sequence: VKEIDIAATLEHV
Position: 933-945
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Positive
Host:  24-36
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 933-945
Chemical type: Peptide from protein
Sequence: VKEIDIAATLEHV
Position: 933-945
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Positive
Host:  17-56
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 933-945
Chemical type: Peptide from protein
Sequence: VKEIDIAATLEHV
Position: 933-945
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Positive
Host:  24-36
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 933-945
Chemical type: Peptide from protein
Sequence: VKEIDIAATLEHV
Position: 933-945
Source molecule (GenBank): AAA90974.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: IA2 933-945
Chemical type: Peptide from protein
Sequence: VKEIDIAATLEHV
Position: 933-945
Source molecule (GenBank): AAA90974.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: IA2 955-967
Chemical type: Peptide from protein
Sequence: KDQFEFALTAVAE
Position: 956-968
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  17-56
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IA2 955-967
Chemical type: Peptide from protein
Sequence: KDQFEFALTAVAE
Position: 956-968
Source molecule (GenBank): AAA90974.1
Assay category: TCell
Result: Negative
Host:  24-36
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo