Reference: Mireille Sebbag; Nathalie Moinard; Isabelle Auger; Cyril Clavel; Jacques Arnaud; Leonor Nogueira; Jean Roudier; Guy Serre. "Epitopes of human fibrin recognized by the rheumatoid arthritis-specific autoantibodies to citrullinated proteins." European journal of immunology (2006).

Epitope: E12Dcit
Chemical type: Peptide from protein
Sequence: ESSRDGSRHPRSHD
Assay category: BCell
Result: Positive

Epitope: T12ECIT
Chemical type: Peptide from protein
Sequence: TGSSTGGRQGSHHE
Assay category: BCell
Result: Positive

Epitope: cfc6
Chemical type: Peptide from protein
Sequence: SHQESTRGRSRGRSGRSGS
Position: 427-445
Source molecule (GenBank): AAA63248.1
Assay category: BCell
Result: Positive

Epitope: cf48-65-4
Chemical type: Peptide from protein
Sequence: TIHAHPGSRRGGRHGYHH
Position: 293-310
Source molecule (GenBank): AAA63244.1
Assay category: BCell
Result: Positive

Epitope: α36-50cit<sub>38,42</sub>
Chemical type: Peptide from protein
Sequence: GPRVVERHQSACKDS
Position: 36-50
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Positive

Epitope: α171-185cit<sub>178,181</sub>
Chemical type: Peptide from protein
Sequence: VDIDIKIRSCRGSCS
Position: 171-185
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Positive

Epitope: α183-197cit<sub>186,190</sub>
Chemical type: Peptide from protein
Sequence: SCSRALAREVDLKDY
Position: 183-197
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Positive

Epitope: α246-260cit<sub>258</sub>
Chemical type: Peptide from protein
Sequence: PEWKALTDMPQMRME
Position: 246-260
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Positive

Epitope: α259-273cit<sub>263,271</sub>
Chemical type: Peptide from protein
Sequence: MELERPGGNEITRGG
Position: 259-273
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Positive

Epitope: α366-380cit<sub>367</sub>
Chemical type: Peptide from protein
Sequence: ERGSAGHWTSESSVS
Position: 366-380
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Positive

Epitope: α396-410cit<sub>404</sub>
Chemical type: Peptide from protein
Sequence: DSPGSGNARPNNPDW
Position: 396-410
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Positive

Epitope: α411-425cit<sub>425</sub>
Chemical type: Peptide from protein
Sequence: GTFEEVSGNVSPGTR
Position: 411-425
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Positive

Epitope: α501-515cit<sub>510,512</sub>
Chemical type: Peptide from protein
Sequence: SGIGTLDGFRHRHPD
Position: 501-515
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Positive

Epitope: α546-560cit<sub>547</sub>
Chemical type: Peptide from protein
Sequence: SRGSESGIFTNTKES
Position: 546-560
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Positive

Epitope: α561-575cit<sub>573</sub>
Chemical type: Peptide from protein
Sequence: SSHHPGIAEFPSRGK
Position: 561-575
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Positive

Epitope: α588-602cit<sub>591</sub>
Chemical type: Peptide from protein
Sequence: SYNRGDSTFESKSYK
Position: 588-602
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Positive

Epitope: α621-635cit<sub>621,627,630</sub>
Chemical type: Peptide from protein
Sequence: RGHAKSRPVRGIHTS
Position: 621-635
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Positive

Epitope: β60-74cit<sub>60,72,74</sub>
Chemical type: Peptide from protein
Sequence: RPAPPPISGGGYRAR
Position: 60-74
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Positive

Epitope: β210-224cit<sub>224</sub>
Chemical type: Peptide from protein
Sequence: QKLESDVSAQMEYCR
Position: 210-224
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Positive

Epitope: β281-295cit<sub>285,294</sub>
Chemical type: Peptide from protein
Sequence: VIQNRQDGSVDFGRK
Position: 281-295
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Positive

Epitope: β420-434cit<sub>421</sub>
Chemical type: Peptide from protein
Sequence: PRKQCSKEDGGGWWY
Position: 420-434
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Positive

Epitope: β433-447cit<sub>436,445</sub>
Chemical type: Peptide from protein
Sequence: WYNRCHAANPNGRYY
Position: 433-447
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Positive

Epitope: α81-95cit<sub>84</sub>
Chemical type: Peptide from protein
Sequence: FTNRINKLKNSLFEY
Position: 81-95
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α111-125cit<sub>114,123</sub>
Chemical type: Peptide from protein
Sequence: EILRGDFSSANNRDN
Position: 111-125
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α126-140cit<sub>129,135,137</sub>
Chemical type: Peptide from protein
Sequence: TYNRVSEDLRSRIEV
Position: 126-140
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α141-155cit<sub>143</sub>
Chemical type: Peptide from protein
Sequence: LKRKVIEKVQHIQLL
Position: 141-155
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α156-170cit<sub>160,168</sub>
Chemical type: Peptide from protein
Sequence: QKNVRAQLVDMKRLE
Position: 156-170
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α186-200cit<sub>186,190</sub>
Chemical type: Peptide from protein
Sequence: RALAREVDLKDYEDQ
Position: 186-200
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α216-230cit<sub>216,218</sub>
Chemical type: Peptide from protein
Sequence: RDRQHLPLIKMKPVP
Position: 216-230
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α261-275cit<sub>263,271</sub>
Chemical type: Peptide from protein
Sequence: LERPGGNEITRGGST
Position: 261-275
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α276-290cit<sub>287</sub>
Chemical type: Peptide from protein
Sequence: SYGTGSETESPRNPS
Position: 276-290
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α306-320cit<sub>308</sub>
Chemical type: Peptide from protein
Sequence: GNRNPGSSGTGGTAT
Position: 306-320
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α351-365cit<sub>353</sub>
Chemical type: Peptide from protein
Sequence: SPRPGSTGTWNPGSS
Position: 351-365
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α381-395cit<sub>394</sub>
Chemical type: Peptide from protein
Sequence: GSTGQWHSESGSFRP
Position: 381-395
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α456-470cit<sub>458,459</sub>
Chemical type: Peptide from protein
Sequence: TTRRSCSKTVTKTVI
Position: 456-470
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α591-605cit<sub>591</sub>
Chemical type: Peptide from protein
Sequence: CPEAMDLGTLSGIGT
Position: 491-505
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: β45-59cit<sub>47,53</sub>
Chemical type: Peptide from protein
Sequence: GHRPLDKKREEAPSL
Position: 45-59
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β75-89cit<sub>87</sub>
Chemical type: Peptide from protein
Sequence: PAKAAATQKKVERKA
Position: 75-89
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β120-134cit<sub>121,124</sub>
Chemical type: Peptide from protein
Sequence: ERPIRNSVDELNNNV
Position: 120-134
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β150-164cit<sub>158</sub>
Chemical type: Peptide from protein
Sequence: LLKDLWQKRQKQVKD
Position: 150-164
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β195-209cit<sub>196,199,206</sub>
Chemical type: Peptide from protein
Sequence: LRVLRSILENLRSKI
Position: 195-209
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β255-269cit<sub>267</sub>
Chemical type: Peptide from protein
Sequence: YLIQPDSSVKPYRVY
Position: 255-269
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β285-299cit<sub>285,294</sub>
Chemical type: Peptide from protein
Sequence: RQDGSVDFGRKWDPY
Position: 285-299
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β375-389cit<sub>376</sub>
Chemical type: Peptide from protein
Sequence: YRGTAGNALMDGASQ
Position: 375-389
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β390-404cit<sub>395</sub>
Chemical type: Peptide from protein
Sequence: LMGENRTMTIHNGMF
Position: 390-404
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β405-419cit<sub>410</sub>
Chemical type: Peptide from protein
Sequence: FSTYDRDNDGWLTSD
Position: 405-419
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β435-449cit<sub>436,445</sub>
Chemical type: Peptide from protein
Sequence: NRCHAANPNGRYYWG
Position: 435-449
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β465-479cit<sub>478</sub>
Chemical type: Peptide from protein
Sequence: VVWMNWKGSWYSMRK
Position: 465-479
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β480-491cit<sub>485</sub>
Chemical type: Peptide from protein
Sequence: MSMKIRPFFPQQ
Position: 480-491
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: α213-227cit<sub>216,218</sub>
Chemical type: Peptide from protein
Sequence: LPSRDRQHLPLIKMK
Position: 213-227
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α347-361cit<sub>353</sub>
Chemical type: Peptide from protein
Sequence: QNPGSPRPGSTGTWN
Position: 347-361
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α363-377cit<sub>367</sub>
Chemical type: Peptide from protein
Sequence: GSSERGSAGHWTSES
Position: 363-377
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α420-434cit<sub>425,426</sub>
Chemical type: Peptide from protein
Sequence: VSPGTRREYHTEKLV
Position: 420-434
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α438-452cit<sub>443</sub>
Chemical type: Peptide from protein
Sequence: GDKELRTGKEKVTSG
Position: 438-452
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α455-469cit<sub>458,459</sub>
Chemical type: Peptide from protein
Sequence: TTTRRSCSKTVTKTV
Position: 455-469
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: α615-629cit<sub>621,627</sub>
Chemical type: Peptide from protein
Sequence: GTHSTKRGHAKSRPV
Position: 615-629
Source molecule (GenBank): NP_068657.1
Assay category: BCell
Result: Negative

Epitope: β50-64cit<sub>53,60</sub>
Chemical type: Peptide from protein
Sequence: DKKREEAPSLRPAPP
Position: 50-64
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β116-130cit<sub>121,124</sub>
Chemical type: Peptide from protein
Sequence: LLQQERPIRNSVDEL
Position: 116-130
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β193-207cit<sub>196,199,206</sub>
Chemical type: Peptide from protein
Sequence: TNLRVLRSILENLRS
Position: 193-207
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β202-216cit<sub>206</sub>
Chemical type: Peptide from protein
Sequence: LENLRSKIQKLESDV
Position: 202-216
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β215-229cit<sub>224</sub>
Chemical type: Peptide from protein
Sequence: DVSAQMEYCRTPCTV
Position: 215-229
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β219-233cit<sub>224</sub>
Chemical type: Peptide from protein
Sequence: QMEYCRTPCTVSCNI
Position: 219-233
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β236-250cit<sub>246</sub>
Chemical type: Peptide from protein
Sequence: VSGKECEEIIRKGGE
Position: 236-250
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β416-430cit<sub>421</sub>
Chemical type: Peptide from protein
Sequence: LTSDPRKQCSKEDGG
Position: 416-430
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative

Epitope: β474-488cit<sub>478,485</sub>
Chemical type: Peptide from protein
Sequence: WYSMRKMSMKIRPFF
Position: 474-488
Source molecule (GenBank): AAA18024.2
Assay category: BCell
Result: Negative