Reference: Iuliia M Gilchuk; Jinhui Dong; Ryan P Irving; Cameron D Buchman; Erica Armstrong; Hannah L Turner; Sheng Li; Andrew B Ward; Robert H Carnahan; James E Crowe. "Pan-H7 influenza human antibody virus neutralization depends on avidity and steric hindrance." JCI insight (2025).

Epitope: Epitope of mAb HNIgGA6 Fab on H7 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y106, A143, T144, S145, R148, G151, S152, W160, D166, H192, S194, V195, E199, K202, L203, A228, R229, P230, Q231, G234, L235, G237
Source molecule (GenBank): AGL44438.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of mAb HNIgGA6 Fab on H7 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y106, A143, T144, S145, R148, G151, S152, W160, D166, H192, S194, V195, E199, K202, L203, A228, R229, P230, Q231, G234, L235, G237
Source molecule (GenBank): AGL44438.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of mAb HNIgGA6 Fab on H7 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y106, A143, T144, S145, R148, G151, S152, W160, D166, H192, S194, V195, E199, K202, L203, A228, R229, P230, Q231, G234, L235, G237
Source molecule (GenBank): AGL44438.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb HNIgGA6 Fab on H7 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y106, A143, T144, S145, R148, G151, S152, W160, D166, H192, S194, V195, E199, K202, L203, A228, R229, P230, Q231, G234, L235, G237
Source molecule (GenBank): AGL44438.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb HNIgGA6 Fab on H7 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y106, A143, T144, S145, R148, G151, S152, W160, D166, H192, S194, V195, E199, K202, L203, A228, R229, P230, Q231, G234, L235, G237
Source molecule (GenBank): AGL44438.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb HNIgGA6 Fab on H7 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y106, A143, T144, S145, R148, G151, S152, W160, D166, H192, S194, V195, E199, K202, L203, A228, R229, P230, Q231, G234, L235, G237
Source molecule (GenBank): AGL44438.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb L4A-14 on H7 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: I138, R139, N141, G142, A143, T144, S145, S152, W160, N164, T165, D166, N167, A168, S196, T197, A198, E199, T201, K202
Source molecule (GenBank): AHZ59759.1
Assay category: BCell
Result: Positive-High
Host: M 86 years

Epitope: Epitope of mAb L4A-14 on H7 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: I138, R139, N141, G142, A143, T144, S145, S152, W160, N164, T165, D166, N167, A168, S196, T197, A198, E199, T201, K202
Source molecule (GenBank): AHZ59759.1
Assay category: BCell
Result: Positive-High
Host: M 86 years

Epitope: Epitope of mAb L4A-14 on H7 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: I138, R139, N141, G142, A143, T144, S145, S152, W160, N164, T165, D166, N167, A168, S196, T197, A198, E199, T201, K202
Source molecule (GenBank): AHZ59759.1
Assay category: BCell
Result: Positive-High
Host: M 86 years

Epitope: Epitope of mAb L4A-14 on H7 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: I138, R139, N141, G142, A143, T144, S145, S152, W160, N164, T165, D166, N167, A168, S196, T197, A198, E199, T201, K202
Source molecule (GenBank): AHZ59759.1
Assay category: BCell
Result: Positive
Host: M 86 years

Epitope: Epitope of mAb L4A-14 on H7 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: I138, R139, N141, G142, A143, T144, S145, S152, W160, N164, T165, D166, N167, A168, S196, T197, A198, E199, T201, K202
Source molecule (GenBank): AHZ59759.1
Assay category: BCell
Result: Positive
Host: M 86 years

Epitope: Epitope of mAb L3A-44 on H7 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: R139, N141, G142, A143, T144, S145, R148, S150, G151, S152, W160, L162, D166, N167, V195, S196, A198, K202, L203, Q231, L235
Source molecule (GenBank): AHZ59759.1
Assay category: BCell
Result: Positive
Host: M 86 years

Epitope: Epitope of mAb L3A-44 on H7 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: R139, N141, G142, A143, T144, S145, R148, S150, G151, S152, W160, L162, D166, N167, V195, S196, A198, K202, L203, Q231, L235
Source molecule (GenBank): AHZ59759.1
Assay category: BCell
Result: Positive-High
Host: M 86 years

Epitope: Epitope of mAb L3A-44 on H7 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: R139, N141, G142, A143, T144, S145, R148, S150, G151, S152, W160, L162, D166, N167, V195, S196, A198, K202, L203, Q231, L235
Source molecule (GenBank): AHZ59759.1
Assay category: BCell
Result: Positive-High
Host: M 86 years

Epitope: Epitope of mAb L3A-44 on H7 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: R139, N141, G142, A143, T144, S145, R148, S150, G151, S152, W160, L162, D166, N167, V195, S196, A198, K202, L203, Q231, L235
Source molecule (GenBank): AHZ59759.1
Assay category: BCell
Result: Positive-Low
Host: M 86 years