Reference: Keke Ma; Jie Wang; Min Jiang; Juanhua He; Fangyang Li; Dan Lu; Chao Su; Yan Chai; Wenjing Jin; Yu Chen; Catherine W H Zhang; Xiaopeng Ma; Hui Tan; George F Gao; Shuguang Tan. "An Engineered Soluble Single-Chain TCR Engager for KRAS-G12V Specific Tumor Immunotherapy." Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2025).

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Quantitative measurement: 2880.0
Host:  8-12 weeks

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Quantitative measurement: 3.45
Host:  8-12 weeks

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Quantitative measurement: 8700.0
Host:  8-12 weeks

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive-Low
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V-9
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo