Reference: Rebecca S Rudicell; Young Do Kwon; Sung-Youl Ko; Amarendra Pegu; Mark K Louder; Ivelin S Georgiev; Xueling Wu; Jiang Zhu; Jeffrey C Boyington; Xuejun Chen; Wei Shi; Zhi-Yong Yang; Nicole A Doria-Rose; Krisha McKee; Sijy O'Dell; Stephen D Schmidt; Gwo-Yu Chuang; Aliaksandr Druz; Cinque Soto; Yongping Yang; Baoshan Zhang; Tongqing Zhou; John-Paul Todd; Krissey E Lloyd; Joshua Eudailey; Kyle E Roberts; Bruce R Donald; Robert T Bailer; Julie Ledgerwood; James C Mullikin; Lawrence Shapiro; Richard A Koup; Barney S Graham; Martha C Nason; Mark Connors; Barton F Haynes; Srinivas S Rao; Mario Roederer; Peter D Kwong; John R Mascola; Gary J Nabel. "Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo." Journal of virology (2014).

Epitope: Epitope of Fab VRC07-G54H on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, E101, E105, N278, T280, N281, N282, A283, K284, S365, G366, G367, D368, I371, G423, R450, D451, G452, G453, A454, N455, N459, E460, T461, R463, G467, K470
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.71
Host: M 56 years

Epitope: Epitope of Fab VRC07-G54H on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, E101, E105, N278, T280, N281, N282, A283, K284, S365, G366, G367, D368, I371, G423, R450, D451, G452, G453, A454, N455, N459, E460, T461, R463, G467, K470
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Host: M 56 years

Epitope: Epitope of Fab VRC07-G54H on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, E101, E105, N278, T280, N281, N282, A283, K284, S365, G366, G367, D368, I371, G423, R450, D451, G452, G453, A454, N455, N459, E460, T461, R463, G467, K470
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Host: M 56 years

Epitope: Epitope of Fab VRC07-G54L on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, E101, E105, N278, T280, N281, N282, A283, K284, S365, G366, G367, D368, I371, G423, D451, G452, G453, A454, N455, N459, E460, T461, R463, G467, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.2
Host: M 56 years

Epitope: Epitope of Fab VRC07-G54L on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, E101, E105, N278, T280, N281, N282, A283, K284, S365, G366, G367, D368, I371, G423, D451, G452, G453, A454, N455, N459, E460, T461, R463, G467, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Host: M 56 years

Epitope: Epitope of Fab VRC07-G54R on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, E101, N278, T280, N281, N282, A283, K284, S365, G366, G367, D368, I371, G423, D451, G452, G453, A454, N455, N459, E460, T461, R463
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Host: M 56 years

Epitope: Epitope of Fab VRC07-G54R on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, E101, N278, T280, N281, N282, A283, K284, S365, G366, G367, D368, I371, G423, D451, G452, G453, A454, N455, N459, E460, T461, R463
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.35
Host: M 56 years

Epitope: Epitope of Fab VRC07-G54W on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, E101,  T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, W421, G423, D451, G452, G453, A454, N455, N459, E460, T461, R463, G467
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.1
Host: M 56 years

Epitope: Epitope of Fab VRC07-G54W on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, E101,  T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, W421, G423, D451, G452, G453, A454, N455, N459, E460, T461, R463, G467
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Host: M 56 years

Epitope: Epitope of Fab VRC07-G54Y on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, N98, E101, N278, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, G423, D451, G452, G453, A454, N455, T457, N459, E460, T461, R463, G467, K470
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Host: M 56 years

Epitope: Epitope of Fab VRC07-G54Y on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, N98, E101, N278, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, G423, D451, G452, G453, A454, N455, T457, N459, E460, T461, R463, G467, K470
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.29
Host: M 56 years