LiteFold/IEDB huggingface dataset:
Reference: Christina L Gardner; Sergei Pletnev; Jinny L Liu; George P Anderson; Lisa C Shriver-Lake; Tatsiana Bylund; Courtney Green; Tyler Stephens; Matthew S Sutton; Yaroslav Tsybovsky; Mario Roederer; Peter D Kwong; Tongqing Zhou; Ellen R Goldman; Crystal W Burke. "Demonstration of  efficacy, cryo-EM-epitope identification, and breadth of two anti-alphavirus bispecific single domain antibodies." Journal of virology (2025).

Epitope: Epitope of sdAb V2B3 on VEEV VLP
Chemical type: Region on multi-chain protein
Discontinuous residues: N: R495, G496, A497, L594, L595, A596, D597; O: T853, V854, N855, L856, D924, C926, L927, A928, E932, Y934, H937, V1020, S1021, N1076, P1077; g: I851, P852, T853, V854, L856, T1019
Source molecule (GenBank): P05674.1
Assay category: BCell
Result: Positive

Epitope: Epitope of sdAb V2C3 on VEEV VLP
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G895, Y897, F899, D909, T910, R1035, K1037, A1038, G1039; J: R352, S360, K556, E558
Source molecule (GenBank): P05674.1
Assay category: BCell
Result: Positive

Epitope: Epitope of sdAb V3A8f on VEEV VLP
Chemical type: Discontinuous protein residues
Discontinuous residues: E533, E535, C536, G537, G538, T539, Q553, Q559
Source molecule (GenBank): P05674.1
Assay category: BCell
Result: Positive
Reference: S Shanmuganathan; Samriddhi Dubey; R Hema Sayee; V Bhanuprakash; Sivarama Krishna Gollapalli; Shreya Gopinath; Suresh Basagoudanavar; B P Sreenivasa; Jitendra Kumar Biswal; Madhusudan Hosamani. "Demonstration of antigenic site 3 in foot-and-mouth disease virus serotype A using neutralizing monoclonal antibody resistant mutants." Microbial pathogenesis (2025).

Epitope: FMDV  G148
Chemical type: Discontinuous protein residues
Discontinuous residues: G148
Source molecule (GenBank): AAM64017.1
Assay category: BCell
Result: Positive

Epitope: FMDV  G148
Chemical type: Discontinuous protein residues
Discontinuous residues: G148
Source molecule (GenBank): AAM64017.1
Assay category: BCell
Result: Positive

Epitope: FMDV  D199
Chemical type: Discontinuous protein residues
Discontinuous residues: D199
Source molecule (GenBank): AAM64017.1
Assay category: BCell
Result: Positive

Epitope: FMDV  D199
Chemical type: Discontinuous protein residues
Discontinuous residues: D199
Source molecule (GenBank): AAM64017.1
Assay category: BCell
Result: Positive

Epitope: FMDV  T48
Chemical type: Discontinuous protein residues
Discontinuous residues: T48
Source molecule (GenBank): AAM64017.1
Assay category: BCell
Result: Positive

Epitope: FMDV  N46, T48
Chemical type: Discontinuous protein residues
Discontinuous residues: N46, T48
Source molecule (GenBank): AAM64017.1
Assay category: BCell
Result: Positive

Epitope: FMDV  V193, E194
Chemical type: Discontinuous protein residues
Discontinuous residues: V193, E194
Source molecule (GenBank): AAM64017.1
Assay category: BCell
Result: Positive
Reference: Giulia Castello; Marjolein M E Isendoorn; Marcel Camps; Nico J Meeuwenoord; Vincent F H Verhoeks; Thomas C van den Ende; Jeroen D C Codée; Ferry Ossendorp; Dmitri V Filippov. "Solid-Phase Synthesis and Immunological Evaluation of Peptide Conjugates Containing Stereochemically Defined UPam-Based TLR2 Ligands and Epitopes from SARS-CoV-2 Virus." Bioconjugate chemistry (2025).

Epitope: VNF long peptide
Chemical type: Peptide from protein
Sequence: LSTDLIKNQCVNFNFNGLTGTGVLTPSS
Position: 515-542
Source molecule (GenBank): 8KDM_A
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: REL long peptide
Chemical type: Peptide from protein
Sequence: KIFVDGVPFVVSTGYHFRELGVVHN
Position: 4724-4748
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: VNF short peptide
Chemical type: Peptide from protein
Sequence: VNFNFNGL
Position: 525-532
Source molecule (GenBank): 8KDM_A
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: REL short peptide
Chemical type: Peptide from protein
Sequence: STGYHFRELG
Position: 4735-4744
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: Mengjiao Wu; Xiaofei Hu; Lu Fan; Bo Wan; Yaning Sun; Yunrui Xing; Lianjun Song; Xianqing Huang; Mei Hu; Gaiping Zhang. "Rapid On-Site Detection of Zearalenone in Maize Using a Colloidal Gold Immunochromatographic Strip." Biosensors (2025).

Epitope: ZAN
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: ZAN
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: ZAN
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: ZAN
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Host: F 6-8 weeks

Epitope: ZAN
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Low
Host: F 6-8 weeks

Epitope: ZEN
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: ZEN
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: ZEN
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: ZEN
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Intermediate
Host: F 6-8 weeks

Epitope: ZEN
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Low
Host: F 6-8 weeks

Epitope: ß-ZEL
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: ß-ZEL
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Low
Host: F 6-8 weeks

Epitope: ZAL
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: ZAL
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: F 6-8 weeks
Reference: Jing Yan; Jessica Min-DeBartolo; Ching-Shin Huang; M Nusrat Sharif; Li Li; Susan Fish; Corey Dower; Denise Murphy; Tatyana Andreyeva; Heng Liu; Xinbing Han; Wei Zheng; Jot Hui Ooi; Jason Edmonds; Ting Chen; Zachary Maben; Chad R Stevens; Polina Goihberg; Malgorzata Nocula-Lugowska; Steven M Evans; Lidia Mosyak; Kerry Kelleher; Caitlyn Dickinson; Martin Hegen; Aaron Winkler; Fridrik Karlsson. "Ligand non-competitive GITR antibody prevents formation of the obligatory signal-triggering GITRL: GITR stoichiometry." Scientific reports (2025).

Epitope: Epitope of hGITR-nc-Ab-#1 on GITR
Chemical type: Discontinuous protein residues
Discontinuous residues: G44, T45, Q76, P77, E78, F79, H91, H92, P93, P95, H124
Source molecule (GenBank): Q9Y5U5.1
Assay category: BCell
Result: Positive

Epitope: Epitope of hGITR-nc-Ab-#1 on GITR
Chemical type: Discontinuous protein residues
Discontinuous residues: G44, T45, Q76, P77, E78, F79, H91, H92, P93, P95, H124
Source molecule (GenBank): Q9Y5U5.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.63

Epitope: Epitope of hGITR-nc-Ab-#1 on GITR
Chemical type: Discontinuous protein residues
Discontinuous residues: G44, T45, Q76, P77, E78, F79, H91, H92, P93, P95, H124
Source molecule (GenBank): Q9Y5U5.1
Assay category: BCell
Result: Positive
Quantitative measurement: 708000.0

Epitope: Epitope of hGITR-nc-Ab-#1 on GITR
Chemical type: Discontinuous protein residues
Discontinuous residues: G44, T45, Q76, P77, E78, F79, H91, H92, P93, P95, H124
Source molecule (GenBank): Q9Y5U5.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000445

Epitope: Epitope of hGITR-nc-Ab-#1 on GITR
Chemical type: Discontinuous protein residues
Discontinuous residues: G44, T45, Q76, P77, E78, F79, H91, H92, P93, P95, H124
Source molecule (GenBank): Q9Y5U5.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.68
Reference: David Vizarraga; Marina Marcos; Noemi Rotllan; Jesús Martín; David Santos; Mercedes Camacho; Begoña Soto; Lorena Velasco-Reniu; Pablo Guerra; Félix Pareja; María Collantes; Wanlu Wu; Irene Rodríguez-Arce; Luis Serrano; Jaume Piñol; Ignacio Fita; Joan Carles Escolà-Gil. "Sources of essential lipids for Mycoplasma pneumoniae via P116 to target liver and atherosclerotic lesions." Nature communications (2025).

Epitope: Epitope of mAb-3G9 on Mycoplasma pneumoniae P116 protein
Chemical type: Discontinuous protein residues
Discontinuous residues: Y398, Q402, K405, K413, T414, A419, A420, S422, P423, E426, H443
Source molecule (GenBank): P75556.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb-3G9 on Mycoplasma pneumoniae P116 protein
Chemical type: Discontinuous protein residues
Discontinuous residues: Y398, Q402, K405, K413, T414, A419, A420, S422, P423, E426, H443
Source molecule (GenBank): P75556.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb-3G9 on Mycoplasma pneumoniae P116 protein
Chemical type: Discontinuous protein residues
Discontinuous residues: Y398, Q402, K405, K413, T414, A419, A420, S422, P423, E426, H443
Source molecule (GenBank): P75556.1
Assay category: BCell
Result: Positive
Reference: Joshua Lugo; Hui Xu; Jeannie Chen; Ali Khoshnan; Ralf Langen. "Epitope-specific antibodies can distinguish between soluble huntingtin exon-1 and its diverse cellular aggregates." The Journal of biological chemistry (2025).

Epitope: Httex1 4-18
Chemical type: Peptide from protein
Sequence: LEKLMKAFESLKSFQ
Position: 4-18
Source molecule (GenBank): P42858.2
Assay category: BCell
Result: Positive

Epitope: Httex1 4-18
Chemical type: Peptide from protein
Sequence: LEKLMKAFESLKSFQ
Position: 4-18
Source molecule (GenBank): P42858.2
Assay category: BCell
Result: Positive

Epitope: Httex1 4-18
Chemical type: Peptide from protein
Sequence: LEKLMKAFESLKSFQ
Position: 4-18
Source molecule (GenBank): P42858.2
Assay category: BCell
Result: Positive

Epitope: Httex1 39-43
Chemical type: Peptide from protein
Sequence: PPPPP
Position: 39-43
Source molecule (GenBank): P42858.2
Assay category: BCell
Result: Positive

Epitope: Httex1 39-43
Chemical type: Peptide from protein
Sequence: PPPPP
Position: 39-43
Source molecule (GenBank): P42858.2
Assay category: BCell
Result: Positive

Epitope: Httex1 39-43
Chemical type: Peptide from protein
Sequence: PPPPP
Position: 39-43
Source molecule (GenBank): P42858.2
Assay category: BCell
Result: Positive
Reference: Jiali Zhu; Zhifeng Chen; Xi Xu; Yuxuan Wang; Pei Liu; Maorong Wen; Quanmeng Wang; Yuchen He; Hongwei Jin; Hongjuan Xue; Shuqing Wang; Ke Xu; Linlin Zhao. "Structure guided analysis of KRAS G12 mutants in HLA-A*11:01 reveals a length encoded immunogenic advantage in G12D." Communications biology (2025).

Epitope: KRAS G12D 9-mer
Chemical type: Neo-epitope
Sequence: VVGADGVGK
Assay category: TCell
Result: Positive-Low
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G12D 9-mer
Chemical type: Neo-epitope
Sequence: VVGADGVGK
Assay category: MhcBinding
Result: Positive

Epitope: KRAS G12D 9-mer
Chemical type: Neo-epitope
Sequence: VVGADGVGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.79

Epitope: KRAS G12C
Chemical type: Neo-epitope
Sequence: VVVGACGVGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.3

Epitope: KRAS G12C
Chemical type: Neo-epitope
Sequence: VVVGACGVGK
Assay category: MhcBinding
Result: Positive

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: VVVGAVGVGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.8

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: VVVGAVGVGK
Assay category: MhcBinding
Result: Positive

Epitope: KRAS G12S
Chemical type: Neo-epitope
Sequence: VVVGASGVGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.8

Epitope: KRAS G12S
Chemical type: Neo-epitope
Sequence: VVVGASGVGK
Assay category: MhcBinding
Result: Positive

Epitope: KRAS G12D 10-mer
Chemical type: Neo-epitope
Sequence: VVVGADGVGK
Assay category: TCell
Result: Positive-High
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G12D 10-mer
Chemical type: Neo-epitope
Sequence: VVVGADGVGK
Assay category: MhcBinding
Result: Positive

Epitope: KRAS WT peptide
Chemical type: Peptide from protein
Sequence: VVVGAGGVGK
Position: 7-16
Source molecule (GenBank): G3V4K2.1
Assay category: MhcBinding
Result: Positive
Reference: Jack Brydon; Radovan Krejcir; Mariana Grima; Filip Zavadil-Kokas; Zuzana Kuncova; Sousan Sousan; Robin L Pflughaupt; Jennifer R Thomson; Paul Davies; Ella Senior; Geoffrey A Wood; Kathryn L Ball; David Saliba; David J Argyle; Borivoj Vojtesek; Ted Hupp; Maciej Parys. "Towards canine immunotherapy models: Monoclonal antibodies with redox regulated epitopes targeting TIM3 attenuate Galectin-9 binding." Analytical biochemistry (2025).

Epitope: Peptide-12
Chemical type: Peptide from protein
Sequence: NLKYQTSNRYRLMRN
Position: 73-87
Source molecule (GenBank): NP_001241644.1
Assay category: BCell
Result: Positive
Quantitative measurement: 24.55

Epitope: Peptide-12
Chemical type: Peptide from protein
Sequence: NLKYQTSNRYRLMRN
Position: 73-87
Source molecule (GenBank): NP_001241644.1
Assay category: BCell
Result: Positive

Epitope: Peptide-12
Chemical type: Peptide from protein
Sequence: NLKYQTSNRYRLMRN
Position: 73-87
Source molecule (GenBank): NP_001241644.1
Assay category: BCell
Result: Positive

Epitope: Peptide-12
Chemical type: Peptide from protein
Sequence: NLKYQTSNRYRLMRN
Position: 73-87
Source molecule (GenBank): NP_001241644.1
Assay category: BCell
Result: Positive-Low

Epitope: Peptide-12
Chemical type: Peptide from protein
Sequence: NLKYQTSNRYRLMRN
Position: 73-87
Source molecule (GenBank): NP_001241644.1
Assay category: BCell
Result: Positive

Epitope: Peptide-12
Chemical type: Peptide from protein
Sequence: NLKYQTSNRYRLMRN
Position: 73-87
Source molecule (GenBank): NP_001241644.1
Assay category: BCell
Result: Positive

Epitope: Peptide-12
Chemical type: Peptide from protein
Sequence: NLKYQTSNRYRLMRN
Position: 73-87
Source molecule (GenBank): NP_001241644.1
Assay category: BCell
Result: Positive

Epitope: Peptide-12
Chemical type: Peptide from protein
Sequence: NLKYQTSNRYRLMRN
Position: 73-87
Source molecule (GenBank): NP_001241644.1
Assay category: BCell
Result: Positive

Epitope: Peptide-12
Chemical type: Peptide from protein
Sequence: NLKYQTSNRYRLMRN
Position: 73-87
Source molecule (GenBank): NP_001241644.1
Assay category: BCell
Result: Positive-High
Quantitative measurement: 2.831

Epitope: Peptide-12
Chemical type: Peptide from protein
Sequence: NLKYQTSNRYRLMRN
Position: 73-87
Source molecule (GenBank): NP_001241644.1
Assay category: BCell
Result: Positive
Quantitative measurement: 29.89

Epitope: Peptide-12
Chemical type: Peptide from protein
Sequence: NLKYQTSNRYRLMRN
Position: 73-87
Source molecule (GenBank): NP_001241644.1
Assay category: BCell
Result: Positive

Epitope: Peptide-12
Chemical type: Peptide from protein
Sequence: NLKYQTSNRYRLMRN
Position: 73-87
Source molecule (GenBank): NP_001241644.1
Assay category: BCell
Result: Positive

Epitope: Peptide-14
Chemical type: Peptide from protein
Sequence: RLMRNFHKGDVSLTI
Position: 83-97
Source molecule (GenBank): NP_001241644.1
Assay category: BCell
Result: Positive

Epitope: Peptide-14
Chemical type: Peptide from protein
Sequence: RLMRNFHKGDVSLTI
Position: 83-97
Source molecule (GenBank): NP_001241644.1
Assay category: BCell
Result: Positive
Reference: Wei Liu; Wei Zhang; Zhuojia Xu; Wenkai Liu; Jiajia Wang; Xia Li; Jian Gao; Tiehai Li. "Chemoenzymatic Synthesis and Antigenicity Evaluation of an O-Antigen Octadecasaccharide from Helicobacter pylori." Angewandte Chemie (International ed. in English) (2026).

Epitope: undecasaccharide 7
Chemical type: Carbohydrate fragment
Assay category: BCell
Result: Positive-High

Epitope: undecasaccharide 7
Chemical type: Carbohydrate fragment
Assay category: BCell
Result: Positive-Low
Reference: Melanie Scherer; Nadia Djabeur; Oliver Siering; Jean-Marc Jeckelmann; Marianne Wyss; Marina Cresci; Morgane Di Palma Subran; Rainer Riedl; Patrick Chames; Christian K Pfaller; Bevan Sawatsky; Dimitrios Fotiadis; Philippe Plattet. "Protection against lethal canine distemper virus infection by a dual epitope-targeting synthetic antibody." Nature communications (2026).

Epitope: Epitope of Nb H7 on CDV H
Chemical type: Discontinuous protein residues
Discontinuous residues: Y387, L460, L479, F481, R484, I494, Q495, S497, Q498, M500, D501, V504, I522, T524, D526, S528, R529, V535, Y537, Y539, A544
Source molecule (GenBank): AAD49703.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000498

Epitope: Epitope of Nb H7 on CDV H
Chemical type: Discontinuous protein residues
Discontinuous residues: Y387, L460, L479, F481, R484, I494, Q495, S497, Q498, M500, D501, V504, I522, T524, D526, S528, R529, V535, Y537, Y539, A544
Source molecule (GenBank): AAD49703.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb H7 on CDV H
Chemical type: Discontinuous protein residues
Discontinuous residues: Y387, L460, L479, F481, R484, I494, Q495, S497, Q498, M500, D501, V504, I522, T524, D526, S528, R529, V535, Y537, Y539, A544
Source molecule (GenBank): AAD49703.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb H7 on CDV H
Chemical type: Discontinuous protein residues
Discontinuous residues: Y387, L460, L479, F481, R484, I494, Q495, S497, Q498, M500, D501, V504, I522, T524, D526, S528, R529, V535, Y537, Y539, A544
Source molecule (GenBank): AAD49703.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb H7 on CDV H
Chemical type: Discontinuous protein residues
Discontinuous residues: Y387, L460, L479, F481, R484, I494, Q495, S497, Q498, M500, D501, V504, I522, T524, D526, S528, R529, V535, Y537, Y539, A544
Source molecule (GenBank): AAD49703.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.29

Epitope: Epitope of Nb H7 on CDV H
Chemical type: Discontinuous protein residues
Discontinuous residues: Y387, L460, L479, F481, R484, I494, Q495, S497, Q498, M500, D501, V504, I522, T524, D526, S528, R529, V535, Y537, Y539, A544
Source molecule (GenBank): AAD49703.1
Assay category: BCell
Result: Positive
Quantitative measurement: 218000.0

Epitope: Epitope of Nb H7 on CDV H
Chemical type: Discontinuous protein residues
Discontinuous residues: Y387, L460, L479, F481, R484, I494, Q495, S497, Q498, M500, D501, V504, I522, T524, D526, S528, R529, V535, Y537, Y539, A544
Source molecule (GenBank): AAD49703.1
Assay category: BCell
Result: Positive
Reference: Shichao Yuan; Rui Fu; Bangfeng Xu; Wenqing Wang; Huamao Ding; Xue Pan; Chunxiu Yuan; Qinfang Liu; Zhifei Zhang; Qiaoyang Teng; Xiaona Shi; Minghao Yan; Peirong Jiao; Dawei Yan; Zejun Li. "Identification of novel B-cell neutralizing epitopes in goose Astrovirus type 2." Veterinary microbiology (2026).

Epitope: Cap 443-450
Chemical type: Peptide from protein
Sequence: ESCSFLVF
Position: 443-450
Source molecule (GenBank): QNS30030.1
Assay category: BCell
Result: Positive

Epitope: Cap 443-450
Chemical type: Peptide from protein
Sequence: ESCSFLVF
Position: 443-450
Source molecule (GenBank): QNS30030.1
Assay category: BCell
Result: Positive

Epitope: Cap 443-450
Chemical type: Peptide from protein
Sequence: ESCSFLVF
Position: 443-450
Source molecule (GenBank): QNS30030.1
Assay category: BCell
Result: Positive

Epitope: Cap 425-434
Chemical type: Peptide from protein
Sequence: QVTPSLVYNF
Position: 425-434
Source molecule (GenBank): QNS30030.1
Assay category: BCell
Result: Positive

Epitope: Cap 425-434
Chemical type: Peptide from protein
Sequence: QVTPSLVYNF
Position: 425-434
Source molecule (GenBank): QNS30030.1
Assay category: BCell
Result: Positive

Epitope: Cap 425-434
Chemical type: Peptide from protein
Sequence: QVTPSLVYNF
Position: 425-434
Source molecule (GenBank): QNS30030.1
Assay category: BCell
Result: Positive
Reference: Daniel Polo-Megías; Mario Cano-Muñoz; Philipp Trolese; Sara Lestani; Ilaria La Rocchia; Andrea Pierangelini; Benedetta Fongaro; Patrizia Polverino de Laureto; Francisco J Morales-Yánez; Jonathan Vaneyck; Alain Vanderplasschen; Thomas Decoville; Géraldine Laumond; M Carmen Salinas-Garcia; Ana Cámara-Artigas; José A Gavira; Christiane Moog; Mireille Dumoulin; Francisco Conejero-Lara. "Neutralizing nanobodies against SARS-CoV-2 recognizing highly conserved epitopes at the Spike's S2 subunit." International journal of biological macromolecules (2026).

Epitope: Epitope of Nb278 on SARS-CoV-2 HR1
Chemical type: Discontinuous protein residues
Discontinuous residues: T961, K964, Q965, S967, S968, N969, G971, A972, I973, S975, V976, D979, I980, R983
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.4

Epitope: Epitope of Nb278 on SARS-CoV-2 HR1
Chemical type: Discontinuous protein residues
Discontinuous residues: T961, K964, Q965, S967, S968, N969, G971, A972, I973, S975, V976, D979, I980, R983
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 12.0

Epitope: Epitope of Nb278 on SARS-CoV-2 HR1
Chemical type: Discontinuous protein residues
Discontinuous residues: T961, K964, Q965, S967, S968, N969, G971, A972, I973, S975, V976, D979, I980, R983
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb278 on SARS-CoV-2 HR1
Chemical type: Discontinuous protein residues
Discontinuous residues: T961, K964, Q965, S967, S968, N969, G971, A972, I973, S975, V976, D979, I980, R983
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb184 on SARS-CoV-2 HR1
Chemical type: Discontinuous protein residues
Discontinuous residues: K921, L922, I923, N925, Q926, F927, N928, S929, A930, K933, D936
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb184 on SARS-CoV-2 HR1
Chemical type: Discontinuous protein residues
Discontinuous residues: K921, L922, I923, N925, Q926, F927, N928, S929, A930, K933, D936
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 900.0

Epitope: Epitope of Nb184 on SARS-CoV-2 HR1
Chemical type: Discontinuous protein residues
Discontinuous residues: K921, L922, I923, N925, Q926, F927, N928, S929, A930, K933, D936
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.4

Epitope: Epitope of Nb184 on SARS-CoV-2 HR1
Chemical type: Discontinuous protein residues
Discontinuous residues: K921, L922, I923, N925, Q926, F927, N928, S929, A930, K933, D936
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive