Reference: Behzod Z Dolimbek; K Roger Aoki; Lance E Steward; Joseph Jankovic; M Zouhair Atassi. "Mapping of the regions on the heavy chain of botulinum neurotoxin A (BoNT/A) recognized by antibodies of cervical dystonia patients with immunoresistance to BoNT/A." Molecular immunology (2007).

Epitope: N1
Chemical type: Peptide from protein
Sequence: ALNDLCIKVNNWDLFFSPS
Position: 449-467
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: N2
Chemical type: Peptide from protein
Sequence: FFSPSEDNFTNDLNKGEEI
Position: 463-481
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: N3
Chemical type: Peptide from protein
Sequence: KGEEITSDTNIEAAEENIS
Position: 477-495
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: N4
Chemical type: Peptide from protein
Sequence: EENISLDLIQQYYLTFNFD
Position: 491-509
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: N5
Chemical type: Peptide from protein
Sequence: TFNFDNEPENISIENLSSD
Position: 505-523
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: N6
Chemical type: Peptide from protein
Sequence: NLSSDIIGQLELMPNIERF
Position: 519-537
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: N7
Chemical type: Peptide from protein
Sequence: NIERFPNGKKYELDKYTMF
Position: 533-551
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: N9
Chemical type: Peptide from protein
Sequence: HGKSRIALTNSVNEALLNP
Position: 561-579
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: N10
Chemical type: Peptide from protein
Sequence: ALLNPSRVYTFFSSDYVKK
Position: 575-593
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: N11
Chemical type: Peptide from protein
Sequence: DYVKKVNKATEAAMFLGWV
Position: 589-607
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: N12
Chemical type: Peptide from protein
Sequence: FLGWVEQLVYDFTDETSEV
Position: 603-621
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: N13
Chemical type: Peptide from protein
Sequence: ETSEVSTTDKIADITIIIP
Position: 617-635
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: N14
Chemical type: Peptide from protein
Sequence: TIIIPYIGPALNIGNMLYK
Position: 631-649
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: N15
Chemical type: Peptide from protein
Sequence: NMLYKDDFVGALIFSGAVI
Position: 645-663
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: N16
Chemical type: Peptide from protein
Sequence: SGAVILLEFIPEIAIPVLG
Position: 659-677
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: N17
Chemical type: Peptide from protein
Sequence: IPVLGTFALVSYIANKVLT
Position: 673-691
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: N19
Chemical type: Peptide from protein
Sequence: KRNEKWDEVYKYIVTNWLA
Position: 701-719
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: N20
Chemical type: Peptide from protein
Sequence: TNWLAKVNTQIDLIRKKMK
Position: 715-733
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: N21
Chemical type: Peptide from protein
Sequence: RKKMKEALENQAEATKAII
Position: 729-747
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: N22
Chemical type: Peptide from protein
Sequence: TKAIINYQYNQYTEEEKNN
Position: 743-761
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: N23
Chemical type: Peptide from protein
Sequence: EEKNNINFNIDDLSSKLNE
Position: 757-775
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: N24
Chemical type: Peptide from protein
Sequence: SKLNESINKAMININKFLN
Position: 771-789
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: N25
Chemical type: Peptide from protein
Sequence: NKFLNQCSVSYLMNSMIPY
Position: 785-803
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: N26
Chemical type: Peptide from protein
Sequence: SMIPYGVKRLEDFDASLKD
Position: 799-817
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: N28
Chemical type: Peptide from protein
Sequence: RGTLIGQVDRLKDKVNNTL
Position: 827-845
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: N29
Chemical type: Peptide from protein
Sequence: VNNTLSTDIPFQLSKYVDN
Position: 841-859
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: C1
Chemical type: Peptide from protein
Sequence: KYVDNQRLLSTFTEYIKNI
Position: 855-873
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C3
Chemical type: Peptide from protein
Sequence: YESNHLIDLSRYASKINIG
Position: 883-901
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C4
Chemical type: Peptide from protein
Sequence: KINIGSKVNFDPIDKNQIQ
Position: 897-915
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C5
Chemical type: Peptide from protein
Sequence: KNQIQLFNLESSKIEVILK
Position: 911-929
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C6
Chemical type: Peptide from protein
Sequence: EVILKNAIVYNSMYENFST
Position: 925-943
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C7
Chemical type: Peptide from protein
Sequence: ENFSTSFWIRIPKYFNSIS
Position: 939-957
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C9
Chemical type: Peptide from protein
Sequence: CMENNSGWKVSLNYGEIIW
Position: 967-985
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C10
Chemical type: Peptide from protein
Sequence: GEIIWTLQDTQEIKQRVVF
Position: 981-999
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C11
Chemical type: Peptide from protein
Sequence: QRVVFKYSQMINISDYINR
Position: 995-1013
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C12
Chemical type: Peptide from protein
Sequence: DYINRWIFVTITNNRLNNS
Position: 1009-1027
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: C13
Chemical type: Peptide from protein
Sequence: RLNNSKIYINGRLIDQKPI
Position: 1023-1041
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: C15
Chemical type: Peptide from protein
Sequence: NNIMFKLDGCRDTHRYIWI
Position: 1051-1069
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C16
Chemical type: Peptide from protein
Sequence: RYIWIKYFNLFDKELNEKE
Position: 1065-1083
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C17
Chemical type: Peptide from protein
Sequence: LNEKEIKDLYDNQSNSGIL
Position: 1079-1097
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: C18
Chemical type: Peptide from protein
Sequence: NSGILKDFWGDYLQYDKPY
Position: 1093-1111
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C19
Chemical type: Peptide from protein
Sequence: YDKPYYMLNLYDPNKYVDV
Position: 1107-1125
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C20
Chemical type: Peptide from protein
Sequence: KYVDVNNVGIRGYMYLKGP
Position: 1121-1139
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C21
Chemical type: Peptide from protein
Sequence: YLKGPRGSVMTTNIYLNSS
Position: 1135-1153
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C22
Chemical type: Peptide from protein
Sequence: YLNSSLYRGTKFIIKKYAS
Position: 1149-1167
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C23
Chemical type: Peptide from protein
Sequence: KKYASGNKDNIVRNNDRVY
Position: 1163-1181
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: C24
Chemical type: Peptide from protein
Sequence: NDRVYINVVVKNKEYRLAT
Position: 1177-1195
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C25
Chemical type: Peptide from protein
Sequence: YRLATNASQAGVEKILSAL
Position: 1191-1209
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: C26
Chemical type: Peptide from protein
Sequence: ILSALEIPDVGNLSQVVVM
Position: 1205-1223
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive

Epitope: C27
Chemical type: Peptide from protein
Sequence: QVVVMKSKNDQGITNKCKM
Position: 1219-1237
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: C29
Chemical type: Peptide from protein
Sequence: IGFIGFHQFNNIAKLVASN
Position: 1247-1265
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative

Epitope: C31
Chemical type: Peptide from protein
Sequence: SRTLGCSWEFIPVDDGWGERPL
Position: 1275-1296
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive