Reference: Alla Kachko; Galina Kochneva; Galina Sivolobova; Antonina Grazhdantseva; Tatyana Lupan; Iryna Zubkova; Frances Wells; Michael Merchlinsky; Ollie Williams; Hisayoshi Watanabe; Alla Ivanova; Aleksander Shvalov; Valeriy Loktev; Sergei Netesov; Marian E Major. "New neutralizing antibody epitopes in hepatitis C virus envelope glycoproteins are revealed by dissecting peptide recognition profiles." Vaccine (2011).

Epitope: Env 192-211
Chemical type: Peptide from protein
Sequence: YQVRNSSGLYHVTNDCPNSS
Position: 192-211
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 208-227
Chemical type: Peptide from protein
Sequence: PNSSIVYEAADAILHTPGCV
Position: 208-227
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 216-235
Chemical type: Peptide from protein
Sequence: AADAILHTPGCVPCVREGNA
Position: 216-235
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 224-243
Chemical type: Peptide from protein
Sequence: PGCVPCVREGNASRCWVAVT
Position: 224-243
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 232-251
Chemical type: Peptide from protein
Sequence: EGNASRCWVAVTPTVATRDG
Position: 232-251
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 248-267
Chemical type: Peptide from protein
Sequence: TRDGKLPTTQLRRHIDLLVG
Position: 248-267
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 256-275
Chemical type: Peptide from protein
Sequence: TQLRRHIDLLVGSATLCSAL
Position: 256-275
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 264-283
Chemical type: Peptide from protein
Sequence: LLVGSATLCSALYVGDLCGS
Position: 264-283
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 264-283
Chemical type: Peptide from protein
Sequence: LLVGSATLCSALYVGDLCGS
Position: 264-283
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 264-283
Chemical type: Peptide from protein
Sequence: LLVGSATLCSALYVGDLCGS
Position: 264-283
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 272-291
Chemical type: Peptide from protein
Sequence: CSALYVGDLCGSVFLVGQLF
Position: 272-291
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 272-291
Chemical type: Peptide from protein
Sequence: CSALYVGDLCGSVFLVGQLF
Position: 272-291
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 280-299
Chemical type: Peptide from protein
Sequence: LCGSVFLVGQLFTFSPRRHW
Position: 280-299
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 280-299
Chemical type: Peptide from protein
Sequence: LCGSVFLVGQLFTFSPRRHW
Position: 280-299
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 288-307
Chemical type: Peptide from protein
Sequence: GQLFTFSPRRHWTTQDCNCS
Position: 288-307
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 288-307
Chemical type: Peptide from protein
Sequence: GQLFTFSPRRHWTTQDCNCS
Position: 288-307
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 296-315
Chemical type: Peptide from protein
Sequence: RRHWTTQDCNCSIYPGHITG
Position: 296-315
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 304-323
Chemical type: Peptide from protein
Sequence: CNCSIYPGHITGHRMAWDMM
Position: 304-323
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 312-331
Chemical type: Peptide from protein
Sequence: HITGHRMAWDMMMNWSPTAA
Position: 312-331
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 320-339
Chemical type: Peptide from protein
Sequence: WDMMMNWSPTAALVVAQLLR
Position: 320-339
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 328-347
Chemical type: Peptide from protein
Sequence: PTAALVVAQLLRIPQAIMDM
Position: 328-347
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 336-355
Chemical type: Peptide from protein
Sequence: QLLRIPQAIMDMIAGAHWGV
Position: 336-355
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 344-363
Chemical type: Peptide from protein
Sequence: IMDMIAGAHWGVLAGIAYFS
Position: 344-363
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 352-371
Chemical type: Peptide from protein
Sequence: HWGVLAGIAYFSMVGNWAKV
Position: 352-371
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 360-379
Chemical type: Peptide from protein
Sequence: AYFSMVGNWAKVLVVLLLFA
Position: 360-379
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 360-379
Chemical type: Peptide from protein
Sequence: AYFSMVGNWAKVLVVLLLFA
Position: 360-379
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-High

Epitope: Env 368-387
Chemical type: Peptide from protein
Sequence: WAKVLVVLLLFAGVDAETHV
Position: 368-387
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 368-387
Chemical type: Peptide from protein
Sequence: WAKVLVVLLLFAGVDAETHV
Position: 368-387
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-High

Epitope: Env 376-395
Chemical type: Peptide from protein
Sequence: LLFAGVDAETHVTGGSAGRT
Position: 376-395
Source molecule (GenBank): AAB02127.1
Assay category: BCell
Result: Negative

Epitope: Env 384-403
Chemical type: Peptide from protein
Sequence: ETHVTGGSAGRTTAGLVGLL
Position: 384-403
Source molecule (GenBank): AAB02127.1
Assay category: BCell
Result: Positive

Epitope: Env 392-411
Chemical type: Peptide from protein
Sequence: AGRTTAGLVGLLTPGAKQNI
Position: 392-411
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 400-419
Chemical type: Peptide from protein
Sequence: VGLLTPGAKQNIQLINTNGS
Position: 400-419
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 408-427
Chemical type: Peptide from protein
Sequence: KQNIQLINTNGSWHINSTAL
Position: 408-427
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 416-435
Chemical type: Peptide from protein
Sequence: TNGSWHINSTALNCNESLNT
Position: 416-435
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 424-443
Chemical type: Peptide from protein
Sequence: STALNCNESLNTGWLAGLFY
Position: 424-443
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 432-451
Chemical type: Peptide from protein
Sequence: SLNTGWLAGLFYQHKFNSSG
Position: 432-451
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 440-459
Chemical type: Peptide from protein
Sequence: GLFYQHKFNSSGCPERLASC
Position: 440-459
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 448-467
Chemical type: Peptide from protein
Sequence: NSSGCPERLASCRRLTDFAQ
Position: 448-467
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 456-475
Chemical type: Peptide from protein
Sequence: LASCRRLTDFAQGWGPISYA
Position: 456-475
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 464-483
Chemical type: Peptide from protein
Sequence: DFAQGWGPISYANGSGLDER
Position: 464-483
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 472-491
Chemical type: Peptide from protein
Sequence: ISYANGSGLDERPYCWHYPP
Position: 472-491
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 480-499
Chemical type: Peptide from protein
Sequence: LDERPYCWHYPPRPCGIVPA
Position: 480-499
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 488-507
Chemical type: Peptide from protein
Sequence: HYPPRPCGIVPAKSVCGPVY
Position: 488-507
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 496-515
Chemical type: Peptide from protein
Sequence: IVPAKSVCGPVYCFTPSPVV
Position: 496-515
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 496-515
Chemical type: Peptide from protein
Sequence: IVPAKSVCGPVYCFTPSPVV
Position: 496-515
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-Low

Epitope: Env 496-515
Chemical type: Peptide from protein
Sequence: IVPAKSVCGPVYCFTPSPVV
Position: 496-515
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 496-515
Chemical type: Peptide from protein
Sequence: IVPAKSVCGPVYCFTPSPVV
Position: 496-515
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-High

Epitope: Env 496-515
Chemical type: Peptide from protein
Sequence: IVPAKSVCGPVYCFTPSPVV
Position: 496-515
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 496-515
Chemical type: Peptide from protein
Sequence: IVPAKSVCGPVYCFTPSPVV
Position: 496-515
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-High

Epitope: Env 496-515
Chemical type: Peptide from protein
Sequence: IVPAKSVCGPVYCFTPSPVV
Position: 496-515
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 496-515
Chemical type: Peptide from protein
Sequence: IVPAKSVCGPVYCFTPSPVV
Position: 496-515
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-High

Epitope: Env 496-515
Chemical type: Peptide from protein
Sequence: IVPAKSVCGPVYCFTPSPVV
Position: 496-515
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-High

Epitope: Env 496-515
Chemical type: Peptide from protein
Sequence: IVPAKSVCGPVYCFTPSPVV
Position: 496-515
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 496-515
Chemical type: Peptide from protein
Sequence: IVPAKSVCGPVYCFTPSPVV
Position: 496-515
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-High

Epitope: Env 504-523
Chemical type: Peptide from protein
Sequence: GPVYCFTPSPVVVGTTDRSG
Position: 504-523
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 512-531
Chemical type: Peptide from protein
Sequence: SPVVVGTTDRSGAPTYSWGA
Position: 512-531
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 512-531
Chemical type: Peptide from protein
Sequence: SPVVVGTTDRSGAPTYSWGA
Position: 512-531
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 512-531
Chemical type: Peptide from protein
Sequence: SPVVVGTTDRSGAPTYSWGA
Position: 512-531
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 520-539
Chemical type: Peptide from protein
Sequence: DRSGAPTYSWGANDTDVFVL
Position: 520-539
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 520-539
Chemical type: Peptide from protein
Sequence: DRSGAPTYSWGANDTDVFVL
Position: 520-539
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 528-547
Chemical type: Peptide from protein
Sequence: SWGANDTDVFVLNNTRPPLG
Position: 528-547
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 528-547
Chemical type: Peptide from protein
Sequence: SWGANDTDVFVLNNTRPPLG
Position: 528-547
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 536-555
Chemical type: Peptide from protein
Sequence: VFVLNNTRPPLGNWFGCTWM
Position: 536-555
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 544-563
Chemical type: Peptide from protein
Sequence: PPLGNWFGCTWMNSTGFTKV
Position: 544-563
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 552-571
Chemical type: Peptide from protein
Sequence: CTWMNSTGFTKVCGAPPCVI
Position: 552-571
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 560-579
Chemical type: Peptide from protein
Sequence: FTKVCGAPPCVIGGVGNNTL
Position: 560-579
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 568-587
Chemical type: Peptide from protein
Sequence: PCVIGGVGNNTLLCPTDCFR
Position: 568-587
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 576-595
Chemical type: Peptide from protein
Sequence: NNTLLCPTDCFRKHPEATYS
Position: 576-595
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 584-603
Chemical type: Peptide from protein
Sequence: DCFRKHPEATYSRCGSGPWI
Position: 584-603
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 592-611
Chemical type: Peptide from protein
Sequence: ATYSRCGSGPWITPRCMVDY
Position: 592-611
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 608-627
Chemical type: Peptide from protein
Sequence: MVDYPYRLWHYPCTINYTIF
Position: 608-627
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 616-635
Chemical type: Peptide from protein
Sequence: WHYPCTINYTIFKVRMYVGG
Position: 616-635
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 624-643
Chemical type: Peptide from protein
Sequence: YTIFKVRMYVGGVEHRLEAA
Position: 624-643
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 632-651
Chemical type: Peptide from protein
Sequence: YVGGVEHRLEAACNWTRGER
Position: 632-651
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 632-651
Chemical type: Peptide from protein
Sequence: YVGGVEHRLEAACNWTRGER
Position: 632-651
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-High

Epitope: Env 632-651
Chemical type: Peptide from protein
Sequence: YVGGVEHRLEAACNWTRGER
Position: 632-651
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 632-651
Chemical type: Peptide from protein
Sequence: YVGGVEHRLEAACNWTRGER
Position: 632-651
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 632-651
Chemical type: Peptide from protein
Sequence: YVGGVEHRLEAACNWTRGER
Position: 632-651
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 632-651
Chemical type: Peptide from protein
Sequence: YVGGVEHRLEAACNWTRGER
Position: 632-651
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 632-651
Chemical type: Peptide from protein
Sequence: YVGGVEHRLEAACNWTRGER
Position: 632-651
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 640-659
Chemical type: Peptide from protein
Sequence: LEAACNWTRGERCDLEDRDR
Position: 640-659
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 640-659
Chemical type: Peptide from protein
Sequence: LEAACNWTRGERCDLEDRDR
Position: 640-659
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 648-667
Chemical type: Peptide from protein
Sequence: RGERCDLEDRDRSELSPLLL
Position: 648-667
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 648-667
Chemical type: Peptide from protein
Sequence: RGERCDLEDRDRSELSPLLL
Position: 648-667
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 656-675
Chemical type: Peptide from protein
Sequence: DRDRSELSPLLLSTTQWQVL
Position: 656-675
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 664-983
Chemical type: Peptide from protein
Sequence: PLLLSTTQWQVLPCSFTTLP
Position: 664-683
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 672-691
Chemical type: Peptide from protein
Sequence: WQVLPCSFTTLPALSTGLIH
Position: 672-691
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 680-699
Chemical type: Peptide from protein
Sequence: TTLPALSTGLIHLHQNIVDV
Position: 680-699
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 688-707
Chemical type: Peptide from protein
Sequence: GLIHLHQNIVDVQYLYGVGS
Position: 688-707
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 696-715
Chemical type: Peptide from protein
Sequence: IVDVQYLYGVGSSIASWAIK
Position: 696-715
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env 702-723
Chemical type: Peptide from protein
Sequence: GVGSSIASWAIKWEYVVLLF
Position: 704-723
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env 710-731
Chemical type: Peptide from protein
Sequence: WAIKWEYVVLLFLLLADARV
Position: 712-731
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative

Epitope: Env (412-426)
Chemical type: Peptide from protein
Sequence: QLINTNGSWHINSTA
Position: 412-426
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-High

Epitope: Env (412-426)
Chemical type: Peptide from protein
Sequence: QLINTNGSWHINSTA
Position: 412-426
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-High

Epitope: Env (412-426)
Chemical type: Peptide from protein
Sequence: QLINTNGSWHINSTA
Position: 412-426
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: Env (412-426)
Chemical type: Peptide from protein
Sequence: QLINTNGSWHINSTA
Position: 412-426
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-High

Epitope: Env (412-426)
Chemical type: Peptide from protein
Sequence: QLINTNGSWHINSTA
Position: 412-426
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-High

Epitope: 391-410 (HVR1-1a)
Chemical type: Peptide from protein
Sequence: SAGRTTAGLVGLLTPGAKQN
Position: 391-410
Source molecule (GenBank): AAB02127.1
Assay category: BCell
Result: Positive

Epitope: 391-410 (HVR1-1a)
Chemical type: Peptide from protein
Sequence: SAGRTTAGLVGLLTPGAKQN
Position: 391-410
Source molecule (GenBank): AAB02127.1
Assay category: BCell
Result: Positive-High

Epitope: 391-410 (HVR1-1a)
Chemical type: Peptide from protein
Sequence: SAGRTTAGLVGLLTPGAKQN
Position: 391-410
Source molecule (GenBank): AAB02127.1
Assay category: BCell
Result: Negative

Epitope: 391-410 (HVR1-1a)
Chemical type: Peptide from protein
Sequence: SAGRTTAGLVGLLTPGAKQN
Position: 391-410
Source molecule (GenBank): AAB02127.1
Assay category: BCell
Result: Negative

Epitope: Env (448-483)
Chemical type: Peptide from protein
Sequence: NSSGCPERLASCRRLTDFAQGWGPISYANGSGLDER
Position: 448-483
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive