Reference: Gonzalo R Acevedo; Natalia A Juiz; Andrea Ziblat; Lucas Pérez Perri; Magalí C Girard; Micaela S Ossowski; Marisa Fernández; Yolanda Hernández; Raúl Chadi; Michael Wittig; Andre Franke; Morten Nielsen; Karina A Gómez. "In Silico Guided Discovery of Novel Class I and II  Epitopes Recognized by T Cells from Chagas' Disease Patients." Journal of immunology (Baltimore, Md. : 1950) (2020).

Epitope: Epitope 2
Chemical type: Peptide from protein
Sequence: GSGVLMEDGTLVFSL
Position: 271-285
Source molecule (GenBank): 1393615446
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 3
Chemical type: Peptide from protein
Sequence: VPYYFANNEFTLVAT
Position: 558-572
Source molecule (GenBank): 1393611437
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 4
Chemical type: Peptide from protein
Sequence: RQYSFVNHRFTLVAT
Position: 549-563
Source molecule (GenBank): 1393582659
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TcTSp1
Chemical type: Peptide from protein
Sequence: ENQLYHFANYKFTLV
Position: 192-206
Source molecule (GenBank): 407842932
Assay category: TCell
Result: Positive
MHC allele types: 18 70 413 774 515 101 318 436 21 67 69 356 74 410 415 1024 323 94
Host:  adult
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 6
Chemical type: Peptide from protein
Sequence: PRGRFLLMRDNLSAL
Position: 130-144
Source molecule (GenBank): 407844899
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 7
Chemical type: Peptide from protein
Sequence: EEKEVMLITAPVYAK
Position: 373-387
Source molecule (GenBank): 1393611437
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TcTSp2
Chemical type: Peptide from protein
Sequence: TVPYHFANSKFTLVA
Position: 528-542
Source molecule (GenBank): 1393611861
Assay category: TCell
Result: Positive
MHC allele types: 94 323 436 18 70 101 515 413 69
Host:  adult
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 11
Chemical type: Peptide from protein
Sequence: VFLSHNFTLVASVTI
Position: 571-585
Source molecule (GenBank): 1393607529
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 12
Chemical type: Peptide from protein
Sequence: NVLLYKRILTAAELR
Position: 674-688
Source molecule (GenBank): 1393609088
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 13
Chemical type: Peptide from protein
Sequence: GRKVMLYTQKVRHSL
Position: 383-397
Source molecule (GenBank): 1393578916
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 14
Chemical type: Peptide from protein
Sequence: NQLYHFANHNFTLVA
Position: 562-576
Source molecule (GenBank): 1393614993
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TcCZp1
Chemical type: Peptide from protein
Sequence: VECQWFLAGHPLTNLS
Position: 156-171
Source molecule (GenBank): 118157
Assay category: TCell
Result: Positive
MHC allele types: 774 323 354 368 18 69 1033 407 94 318 365
Host:  adult
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TcTSp3
Chemical type: Peptide from protein
Sequence: MLSLVAAVKAPRTHN
Position: 1-15
Source molecule (GenBank): 1393610886
Assay category: TCell
Result: Positive
MHC allele types: 436 94 323 18 70 413 69 101
Host:  adult
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 17
Chemical type: Peptide from protein
Sequence: KLLELSVYNCDLAMR
Position: 391-405
Source molecule (GenBank): 1393615668
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 18
Chemical type: Peptide from protein
Sequence: FRRLYKTLGQLVYKK
Position: 447-461
Source molecule (GenBank): 1393615668
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 19
Chemical type: Peptide from protein
Sequence: SFVNHRFTLVATVTI
Position: 552-566
Source molecule (GenBank): 1393582659
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TcTSp4
Chemical type: Peptide from protein
Sequence: GVVMEDGTLVFPLMA
Position: 269-283
Source molecule (GenBank): 1393576397
Assay category: TCell
Result: Positive
MHC allele types: 769 321 53 1024 317 415 774 318 358 18 67 360 21 76 94 323 436 70 65 1031 69 424 976 324 407 365 73 71 1032 75 72 914 428 419
Host:  adult
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 21
Chemical type: Peptide from protein
Sequence: KVMLYTQKVRHSLEV
Position: 385-399
Source molecule (GenBank): 1393578916
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 23
Chemical type: Peptide from protein
Sequence: EAENHRALAALYELV
Position: 22-36
Source molecule (GenBank): 407844899
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 24
Chemical type: Peptide from protein
Sequence: RNVMLVTLPVFSKKA
Position: 389-403
Source molecule (GenBank): 1393592459
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 25
Chemical type: Peptide from protein
Sequence: NMSRHLFYSAVLLLL
Position: 38-52
Source molecule (GenBank): 1393615918
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 26
Chemical type: Peptide from protein
Sequence: GDSVYMLLGNYSRTK
Position: 182-196
Source molecule (GenBank): 1393590223
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 27
Chemical type: Peptide from protein
Sequence: LNRQYTFVDYNFSLV
Position: 543-557
Source molecule (GenBank): 407859280
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 28
Chemical type: Peptide from protein
Sequence: RPNMSRHLFYSAVLL
Position: 36-50
Source molecule (GenBank): 1393615918
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 29
Chemical type: Peptide from protein
Sequence: AGYIKAAESWPSIVA
Position: 144-158
Source molecule (GenBank): 1393599283
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 30
Chemical type: Peptide from protein
Sequence: SVYNCDLAMRCIGMM
Position: 396-410
Source molecule (GenBank): 1393615668
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 31
Chemical type: Peptide from protein
Sequence: IDGQKVILVSRPVYS
Position: 367-381
Source molecule (GenBank): 1393600992
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 32
Chemical type: Peptide from protein
Sequence: ANYNFTLVATVSIHK
Position: 536-550
Source molecule (GenBank): 3298145
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 33
Chemical type: Peptide from protein
Sequence: GNELFLLVGSSYFVF
Position: 193-207
Source molecule (GenBank): 1393609088
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 34
Chemical type: Peptide from protein
Sequence: YEFVNACAKLMHQIL
Position: 224-238
Source molecule (GenBank): 407844899
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 35
Chemical type: Peptide from protein
Sequence: VPVTVTNVLLYNRPL
Position: 96-110
Source molecule (GenBank): 407842369
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 36
Chemical type: Peptide from protein
Sequence: YVDLMAELRAELSEL
Position: 168-182
Source molecule (GenBank): 407844899
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 37
Chemical type: Peptide from protein
Sequence: VTNVFLYNRPLNPTE
Position: 162-176
Source molecule (GenBank): 112861
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TcTSp5
Chemical type: Peptide from protein
Sequence: HRFTLVATVTIHQVPK
Position: 514-529
Source molecule (GenBank): 1393594126
Assay category: TCell
Result: Positive
MHC allele types: 18 70 101 515 413 774 318 356 410 69 415 1024 323 94 547 750 1026 770 317 74 21 408 1023 363 365 1031 436 67 68 431 360 358
Host:  adult
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 40
Chemical type: Peptide from protein
Sequence: KEVMLITAPVYPKDN
Position: 366-380
Source molecule (GenBank): 1243007204
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 41
Chemical type: Peptide from protein
Sequence: PNMSRHLFTSAVLLL
Position: 37-51
Source molecule (GenBank): 1393617283
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 42
Chemical type: Peptide from protein
Sequence: HFANYNFTLVATVSV
Position: 580-594
Source molecule (GenBank): 1393602586
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 43
Chemical type: Peptide from protein
Sequence: IPTAGLVAVFSNASA
Position: 508-522
Source molecule (GenBank): 1393607529
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 44
Chemical type: Peptide from protein
Sequence: SELLAASKELRERYR
Position: 62-76
Source molecule (GenBank): 407844899
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 45
Chemical type: Peptide from protein
Sequence: HQVALMLQGNKASVY
Position: 81-95
Source molecule (GenBank): 112861
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 46
Chemical type: Peptide from protein
Sequence: VTFQGAWAEWPVGSQ
Position: 562-576
Source molecule (GenBank): 1393599075
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TcCZp2
Chemical type: Peptide from protein
Sequence: RQRRYQPYHSRHRRL
Position: 453-467
Source molecule (GenBank): 1393607585
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TcCZp2
Chemical type: Peptide from protein
Sequence: RQRRYQPYHSRHRRL
Position: 453-467
Source molecule (GenBank): 1393607585
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 48
Chemical type: Peptide from protein
Sequence: GKVKDIFASPALVRA
Position: 61-75
Source molecule (GenBank): 473768
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 49
Chemical type: Peptide from protein
Sequence: GSGIVMGNGTLVFPL
Position: 265-279
Source molecule (GenBank): 1393578916
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 50
Chemical type: Peptide from protein
Sequence: RHVFLSHDFTLVATV
Position: 586-600
Source molecule (GenBank): 1393593476
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TcCZp2me
Chemical type: Peptide from protein
Sequence: RYQPYHSRHR
Position: 456-465
Source molecule (GenBank): 1393607585
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TcCZp2me
Chemical type: Peptide from protein
Sequence: RYQPYHSRHR
Position: 456-465
Source molecule (GenBank): 1393607585
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo