Reference: C Loftus; E Huseby; P Gopaul; C Beeson; J Goverman. "Highly cross-reactive T cell responses to myelin basic protein epitopes reveal a nonpredictable form of TCR degeneracy." Journal of immunology (Baltimore, Md. : 1950) (1999).

Epitope: 121-140
Chemical type: Peptide from protein
Sequence: GFGYGGRASDYKSAHKGFKG
Position: 122-141
Source molecule (GenBank): AAA39496.1
Assay category: TCell
Result: Positive
Host:  5-10 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: 121-140
Chemical type: Peptide from protein
Sequence: GFGYGGRASDYKSAHKGFKG
Position: 122-141
Source molecule (GenBank): AAA39496.1
Assay category: TCell
Result: Positive
Host:  5-10 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: 121-140
Chemical type: Peptide from protein
Sequence: GFGYGGRASDYKSAHKGFKG
Position: 122-141
Source molecule (GenBank): AAA39496.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 12000.0

Epitope: 124-140
Chemical type: Peptide from protein
Sequence: YGGRASDYKSAHKGFKG
Position: 125-141
Source molecule (GenBank): AAA39496.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 12780.0

Epitope: 125-140
Chemical type: Peptide from protein
Sequence: GGRASDYKSAHKGFKG
Position: 126-141
Source molecule (GenBank): AAA39496.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 12600.0

Epitope: 126-140
Chemical type: Peptide from protein
Sequence: GRASDYKSAHKGFKG
Position: 127-141
Source molecule (GenBank): AAA39496.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 4560.0

Epitope: 127-140
Chemical type: Peptide from protein
Sequence: RASDYKSAHKGFKG
Position: 128-141
Source molecule (GenBank): AAA39496.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 504.0

Epitope: 128-140
Chemical type: Peptide from protein
Sequence: ASDYKSAHKGFKG
Position: 129-141
Source molecule (GenBank): AAA39496.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 312.0

Epitope: 129-140
Chemical type: Peptide from protein
Sequence: SDYKSAHKGFKG
Position: 130-141
Source molecule (GenBank): AAA39496.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 60.0

Epitope: 130-140
Chemical type: Peptide from protein
Sequence: DYKSAHKGFKG
Position: 131-141
Source molecule (GenBank): AAA39496.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 60.0

Epitope: 126-140, G126I
Chemical type: Peptide, no natural source
Sequence: IRASDYKSAHKGFKG
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 7500.0

Epitope: 126-140, A128T
Chemical type: Peptide, no natural source
Sequence: GRTSDYKSAHKGFKG
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 300.0

Epitope: 126-140, A128I
Chemical type: Peptide, no natural source
Sequence: GRISDYKSAHKGFKG
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 60.0

Epitope: 126-140, S129E
Chemical type: Peptide, no natural source
Sequence: GRAEDYKSAHKGFKG
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 180.0

Epitope: 126-140, D130A
Chemical type: Peptide, no natural source
Sequence: GRASAYKSAHKGFKG
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1680.0

Epitope: 126-140, Y131E
Chemical type: Peptide, no natural source
Sequence: GRASDEKSAHKGFKG
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 60.0

Epitope: 125-135 (core 1)
Chemical type: Peptide from protein
Sequence: GGRASDYKSAH
Position: 126-136
Source molecule (GenBank): AAA39496.1
Assay category: TCell
Result: Positive
Host:  5-10 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: 125-135 (core 1)
Chemical type: Peptide from protein
Sequence: GGRASDYKSAH
Position: 126-136
Source molecule (GenBank): AAA39496.1
Assay category: TCell
Result: Positive
Host:  5-10 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: 125-135 (core 1)
Chemical type: Peptide from protein
Sequence: GGRASDYKSAH
Position: 126-136
Source molecule (GenBank): AAA39496.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 16200.0

Epitope: 125-135, R127A
Chemical type: Peptide, no natural source
Sequence: GGAASDYKSAH
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1440.0

Epitope: 125-135, S133E
Chemical type: Peptide, no natural source
Sequence: GGRASDYKEAH
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 16200.0

Epitope: 125-135, S133A
Chemical type: Peptide, no natural source
Sequence: GGRASDYKAAH
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 16200.0

Epitope: 132-144
Chemical type: Peptide from protein
Sequence: KSAHKGFKGAYDA
Position: 133-145
Source molecule (GenBank): AAA39496.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 120.0

Epitope: 136-148
Chemical type: Peptide from protein
Sequence: KGFKGAYDAQGTL
Position: 137-149
Source molecule (GenBank): AAA39496.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1200.0

Epitope: 134-146
Chemical type: Peptide from protein
Sequence: AHKGFKGAYDAQG
Position: 135-147
Source molecule (GenBank): AAA39496.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10800.0

Epitope: 140-150
Chemical type: Peptide from protein
Sequence: GAYDAQGTLSK
Position: 141-151
Source molecule (GenBank): AAA39496.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 60.0

Epitope: 136-146 (core 2)
Chemical type: Peptide from protein
Sequence: KGFKGAYDAQG
Position: 137-147
Source molecule (GenBank): AAA39496.1
Assay category: TCell
Result: Positive
Host:  5-10 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: 136-146 (core 2)
Chemical type: Peptide from protein
Sequence: KGFKGAYDAQG
Position: 137-147
Source molecule (GenBank): AAA39496.1
Assay category: TCell
Result: Positive
Host:  5-10 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: 136-146 (core 2)
Chemical type: Peptide from protein
Sequence: KGFKGAYDAQG
Position: 137-147
Source molecule (GenBank): AAA39496.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10800.0

Epitope: 136-146, G137I
Chemical type: Peptide, no natural source
Sequence: KIFKGAYDAQG
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10800.0

Epitope: 136-146, F138A
Chemical type: Peptide, no natural source
Sequence: KGAKGAYDAQG
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10200.0

Epitope: 136-146, F138Y
Chemical type: Peptide, no natural source
Sequence: KGYKGAYDAQG
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10800.0

Epitope: 136-146, K139A
Chemical type: Peptide, no natural source
Sequence: KGFAGAYDAQG
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 300.0

Epitope: 136-146, A141D
Chemical type: Peptide, no natural source
Sequence: KGFKGDYDAQG
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1800.0

Epitope: 136-146, Y142E
Chemical type: Peptide, no natural source
Sequence: KGFKGAEDAQG
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 60.0

Epitope: 136-146, D143A
Chemical type: Peptide, no natural source
Sequence: KGFKGAYAAQG
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 900.0

Epitope: 136-146, A144Q
Chemical type: Peptide, no natural source
Sequence: KGFKGAYDQQG
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 60.0

Epitope: 136-146, Q145A
Chemical type: Peptide, no natural source
Sequence: KGFKGAYDAAG
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 60.0

Epitope: 125-135 G126A
Chemical type: Peptide, no natural source
Sequence: GARASDYKSAH
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1440.0

Epitope: 125-135 S129A
Chemical type: Peptide, no natural source
Sequence: GGRAADYKSAH
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2400.0

Epitope: 125-135 K132A
Chemical type: Peptide, no natural source
Sequence: GGRASDYASAH
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 16200.0

Epitope: 125-135 K132A
Chemical type: Peptide, no natural source
Sequence: GGRASDYESAH
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 16200.0

Epitope: 136-146 FAA
Chemical type: Peptide, no natural source
Sequence: KFFKAAYAAQG
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10800.0

Epitope: 136-146 G137A
Chemical type: Peptide, no natural source
Sequence: KAFKGAYDAQG
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10200.0

Epitope: 136-146 G140D
Chemical type: Peptide, no natural source
Sequence: KGFKDAYDAQG
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1800.0