Reference: Marvin Lin; Cristina Stoica-Nazarov; Jacqueline Surls; Margaret Kehl; Constantin Bona; Cara Olsen; Teodor D Brumeanu; Sofia Casares. "Reversal of type 1 diabetes by a new MHC II-peptide chimera: "Single-epitope-mediated suppression" to stabilize a polyclonal autoimmune T-cell process." European journal of immunology (2010).

Epitope: GAD65<sub>217-230</sub>
Chemical type: Peptide from protein
Sequence: EYVTLKKMREIIGW
Position: 217-230
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Negative
Host: F 3 months
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD65<sub>217-230</sub>
Chemical type: Peptide from protein
Sequence: EYVTLKKMREIIGW
Position: 217-230
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive
Host: F 3 months
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD65<sub>217-230</sub>
Chemical type: Peptide from protein
Sequence: EYVTLKKMREIIGW
Position: 217-230
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive
Host: F 2-3 months

Epitope: GAD65<sub>217-230</sub>
Chemical type: Peptide from protein
Sequence: EYVTLKKMREIIGW
Position: 217-230
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive
Host: F 4-5 months

Epitope: GAD65<sub>217-230</sub>
Chemical type: Peptide from protein
Sequence: EYVTLKKMREIIGW
Position: 217-230
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Negative
Host: F 4 months
Cell type: lymphocyte
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: GAD65<sub>217-230</sub>
Chemical type: Peptide from protein
Sequence: EYVTLKKMREIIGW
Position: 217-230
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Negative
Host: F 4 months
Cell type: lymphocyte
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: GAD65<sub>217-230</sub>
Chemical type: Peptide from protein
Sequence: EYVTLKKMREIIGW
Position: 217-230
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Negative
Host: F 4 months
Cell type: lymphocyte
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: GAD65<sub>217-230</sub>
Chemical type: Peptide from protein
Sequence: EYVTLKKMREIIGW
Position: 217-230
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive
Host: F 4 months
Cell type: lymphocyte
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: GAD65<sub>217-230</sub>
Chemical type: Peptide from protein
Sequence: EYVTLKKMREIIGW
Position: 217-230
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Negative
Host: F 4 months
Cell type: lymphocyte
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: GAD65<sub>217-230</sub>
Chemical type: Peptide from protein
Sequence: EYVTLKKMREIIGW
Position: 217-230
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive
Host: F 2-3 months
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD65<sub>217-230</sub>
Chemical type: Peptide from protein
Sequence: EYVTLKKMREIIGW
Position: 217-230
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Negative
Host: F 4 months
Cell type: lymphocyte
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: GAD65<sub>217-230</sub>
Chemical type: Peptide from protein
Sequence: EYVTLKKMREIIGW
Position: 217-230
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Negative
Host: F 4 months
Cell type: lymphocyte
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: GAD65<sub>217-230</sub>
Chemical type: Peptide from protein
Sequence: EYVTLKKMREIIGW
Position: 217-230
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive-High
Host: F 4 months
Cell type: lymphocyte
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Insulin B-chain 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): AAI45555.1
Assay category: TCell
Result: Negative
Host: F 4 months
Cell type: lymphocyte
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Insulin B-chain 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): AAI45555.1
Assay category: TCell
Result: Negative
Host: F 4 months
Cell type: lymphocyte
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Insulin B-chain 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): AAI45555.1
Assay category: TCell
Result: Negative
Host: F 4 months
Cell type: lymphocyte
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Insulin B-chain 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): AAI45555.1
Assay category: TCell
Result: Positive
Host: F 4 months
Cell type: lymphocyte
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Insulin B-chain 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): AAI45555.1
Assay category: TCell
Result: Negative
Host: F 4 months
Cell type: lymphocyte
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Insulin B-chain 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): AAI45555.1
Assay category: TCell
Result: Negative
Host: F 4 months
Cell type: lymphocyte
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Insulin B-chain 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): AAI45555.1
Assay category: TCell
Result: Positive
Host: F 4 months
Cell type: lymphocyte
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Insulin B-chain 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): AAI45555.1
Assay category: TCell
Result: Negative
Host: F 4 months
Cell type: lymphocyte
Tissue: pancreas
Culture conditions: Direct Ex Vivo