Reference: B L McRae; C L Vanderlugt; M C Dal Canto; S D Miller. "Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis." The Journal of experimental medicine (1995).

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP (139-151)
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP (178-191)M
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSK
Position: 179-192
Source molecule (GenBank): CAA30184.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP (178-191)M
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSK
Position: 179-192
Source molecule (GenBank): CAA30184.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP (178-191)M
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSK
Position: 179-192
Source molecule (GenBank): CAA30184.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP (178-191)M
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSK
Position: 179-192
Source molecule (GenBank): CAA30184.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP (178-191)M
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSK
Position: 179-192
Source molecule (GenBank): CAA30184.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP (178-191)M
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSK
Position: 179-192
Source molecule (GenBank): CAA30184.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP (178-191)M
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSK
Position: 179-192
Source molecule (GenBank): CAA30184.1
Assay category: TCell
Result: Positive-High
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP (178-191)M
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSK
Position: 179-192
Source molecule (GenBank): CAA30184.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP (178-191)M
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSK
Position: 179-192
Source molecule (GenBank): CAA30184.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP (178-191)B
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAAPSK
Position: 179-192
Source molecule (GenBank): P04116.3
Assay category: TCell
Result: Positive-High
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP (178-191)B
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAAPSK
Position: 179-192
Source molecule (GenBank): P04116.3
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP (178-191)B
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAAPSK
Position: 179-192
Source molecule (GenBank): P04116.3
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP (104-117)
Chemical type: Peptide from protein
Sequence: KTTICGKGLSATVT
Position: 105-118
Source molecule (GenBank): CAA30184.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MBP (84-104)
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTPPPSQGKGR
Position: 85-105
Source molecule (GenBank): AAA39496.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks

Epitope: MBP (84-104)
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTPPPSQGKGR
Position: 85-105
Source molecule (GenBank): AAA39496.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: MBP (84-104)
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTPPPSQGKGR
Position: 85-105
Source molecule (GenBank): AAA39496.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: MBP (84-104)
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTPPPSQGKGR
Position: 85-105
Source molecule (GenBank): AAA39496.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MBP (84-104)
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTPPPSQGKGR
Position: 85-105
Source molecule (GenBank): AAA39496.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks