Reference: Nicholas McGranahan; Andrew J S Furness; Rachel Rosenthal; Sofie Ramskov; Rikke Lyngaa; Sunil Kumar Saini; Mariam Jamal-Hanjani; Gareth A Wilson; Nicolai J Birkbak; Crispin T Hiley; Thomas B K Watkins; Seema Shafi; Nirupa Murugaesu; Richard Mitter; Ayse U Akarca; Joseph Linares; Teresa Marafioti; Jake Y Henry; Eliezer M Van Allen; Diana Miao; Bastian Schilling; Dirk Schadendorf; Levi A Garraway; Vladimir Makarov; Naiyer A Rizvi; Alexandra Snyder; Matthew D Hellmann; Taha Merghoub; Jedd D Wolchok; Sachet A Shukla; Catherine J Wu; Karl S Peggs; Timothy A Chan; Sine R Hadrup; Sergio A Quezada; Charles Swanton. "Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade." Science (New York, N.Y.) (2016).

Epitope: MTFR2 D326Y
Chemical type: Peptide, no natural source
Sequence: FAFQEYDSF
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: MTFR2 D326Y
Chemical type: Peptide, no natural source
Sequence: FAFQEYDSF
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Non-antigen specific activation

Epitope: MTFR2 D326Y
Chemical type: Peptide, no natural source
Sequence: FAFQEYDSF
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: CHTF18 L769V
Chemical type: Peptide, no natural source
Sequence: LLLDIVAPK
Assay category: TCell
Result: Positive
Host: F 69 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: CHTF18 L769V
Chemical type: Peptide, no natural source
Sequence: LLLDIVAPK
Assay category: TCell
Result: Positive
Host: F 69 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Non-antigen specific activation

Epitope: CHTF18 L769V
Chemical type: Peptide, no natural source
Sequence: LLLDIVAPK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: MYADM R30W
Chemical type: Peptide, no natural source
Sequence: SPMIVGSPW
Assay category: TCell
Result: Positive
Host: F 69 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: MYADM R30W
Chemical type: Peptide, no natural source
Sequence: SPMIVGSPW
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: MYADM R30W
Chemical type: Peptide, no natural source
Sequence: SPMIVGSPW
Assay category: TCell
Result: Positive
Host: F 69 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Non-antigen specific activation

Epitope: MTFR2 wt
Chemical type: Peptide from protein
Sequence: FAFQEDDSF
Position: 321-329
Source molecule (GenBank): NP_001092756.1
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Non-antigen specific activation

Epitope: MYADM wt
Chemical type: Peptide from protein
Sequence: SPMIVGSPR
Position: 22-30
Source molecule (GenBank): NP_612382.1
Assay category: TCell
Result: Positive
Host: F 69 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Non-antigen specific activation

Epitope: MTFR2 D326Y (AFQEYDSFEK)
Chemical type: Peptide, no natural source
Sequence: AFQEYDSFEK
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Non-antigen specific activation

Epitope: MTFR2 D326Y (KFAFQEYDSF)
Chemical type: Peptide, no natural source
Sequence: KFAFQEYDSF
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Non-antigen specific activation

Epitope: CHTF18 L769V (CLLLDIVAPK)
Chemical type: Peptide, no natural source
Sequence: CLLLDIVAPK
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Non-antigen specific activation

Epitope: CHTF18 L769V (IVAPKLRPV)
Chemical type: Peptide, no natural source
Sequence: IVAPKLRPV
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Non-antigen specific activation

Epitope: MYADM R30W (SPMIVGSPWAL)
Chemical type: Peptide, no natural source
Sequence: SPMIVGSPWAL
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Non-antigen specific activation

Epitope: MYADM R30W (SPWALTQPL)
Chemical type: Peptide, no natural source
Sequence: SPWALTQPL
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Non-antigen specific activation

Epitope: HCMV pp65
Chemical type: Peptide from protein
Sequence: GPISGHVLK
Position: 16-24
Source molecule (GenBank): ADV04400.1
Assay category: TCell
Result: Positive-Low
Host: F 49 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Non-antigen specific activation

Epitope: EBV EBNA4
Chemical type: Peptide from protein
Sequence: AVFDRKSDAK
Position: 399-408
Source molecule (GenBank): Q3KST1.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Non-antigen specific activation