Reference: Yuexin Xu; Alicia J Morales; Michael J Cargill; Andrea M H Towlerton; David G Coffey; Edus H Warren; Scott S Tykodi. "Preclinical development of T-cell receptor-engineered T-cell therapy targeting the 5T4 tumor antigen on renal cell carcinoma." Cancer immunology, immunotherapy : CII (2019).

Epitope: 5T4 17–25
Chemical type: Peptide from protein
Sequence: RLARLALVL
Position: 17-25
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Host: M 60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: 5T4 17–25
Chemical type: Peptide from protein
Sequence: RLARLALVL
Position: 17-25
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: 5T4 17–25
Chemical type: Peptide from protein
Sequence: RLARLALVL
Position: 17-25
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Host: M 60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: 5T4 17–25
Chemical type: Peptide from protein
Sequence: RLARLALVL
Position: 17-25
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: 5T4 17–25
Chemical type: Peptide from protein
Sequence: RLARLALVL
Position: 17-25
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Host: M 60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: 5T4 17–25
Chemical type: Peptide from protein
Sequence: RLARLALVL
Position: 17-25
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Host: M 60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: 5T4 17–25
Chemical type: Peptide from protein
Sequence: RLARLALVL
Position: 17-25
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: 5T4 17–25
Chemical type: Peptide from protein
Sequence: RLARLALVL
Position: 17-25
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: 5T4 17–25
Chemical type: Peptide from protein
Sequence: RLARLALVL
Position: 17-25
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Host: M 60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: 5T4 17–25
Chemical type: Peptide from protein
Sequence: RLARLALVL
Position: 17-25
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: 5T4 17–25
Chemical type: Peptide from protein
Sequence: RLARLALVL
Position: 17-25
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: 5T4 17–25
Chemical type: Peptide from protein
Sequence: RLARLALVL
Position: 17-25
Source molecule (GenBank): Q13641.1
Assay category: MhcBinding
Result: Positive

Epitope: L5A
Chemical type: Peptide, no natural source
Sequence: RLARAALVL
Assay category: MhcBinding
Result: Negative

Epitope: V8A
Chemical type: Peptide, no natural source
Sequence: RLARLALAL
Assay category: MhcBinding
Result: Negative