Reference: Parisa Malekzadeh; Anna Pasetto; Paul F Robbins; Maria R Parkhurst; Biman C Paria; Li Jia; Jared J Gartner; Victoria Hill; Zhiya Yu; Nicholas P Restifo; Abraham Sachs; Eric Tran; Winifred Lo; Robert Pt Somerville; Steven A Rosenberg; Drew C Deniger. "Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers." The Journal of clinical investigation (2019).

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: HMTEVVRHC
Assay category: TCell
Result: Positive
Host:  36-52 years
Cell type: T cell CD8+
Tissue: metastatic site
Culture conditions: Direct Ex Vivo

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: HMTEVVRHC
Assay category: TCell
Result: Negative
Host:  36-52 years
Cell type: T cell CD8+
Tissue: metastatic site
Culture conditions: Direct Ex Vivo

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: HMTEVVRHC
Assay category: TCell
Result: Positive
Host:  36-52 years
Cell type: tumor infiltrating lymphocyte
Tissue: metastatic site
Culture conditions: Direct Ex Vivo

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: HMTEVVRHC
Assay category: TCell
Result: Negative
Host:  36-52 years
Cell type: tumor infiltrating lymphocyte
Tissue: metastatic site
Culture conditions: Direct Ex Vivo

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: HMTEVVRHC
Assay category: TCell
Result: Negative
Host:  36-52 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: HMTEVVRHC
Assay category: TCell
Result: Positive
Host:  36-52 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: YKQSQHMTEVVRHCPHHERCSDSDG
Assay category: TCell
Result: Positive
Host: M 55 years
Cell type: T cell CD4+
Tissue: metastatic site
Culture conditions: Direct Ex Vivo

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: YKQSQHMTEVVRHCPHHERCSDSDG
Assay category: TCell
Result: Negative
Host: M 55 years
Cell type: T cell CD4+
Tissue: metastatic site
Culture conditions: Direct Ex Vivo

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: VVRHCPHHERCSDSD
Assay category: TCell
Result: Negative
Host: M 46 years
Cell type: T cell CD4+
Tissue: metastatic site
Culture conditions: Direct Ex Vivo

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: VVRHCPHHERCSDSD
Assay category: TCell
Result: Positive
Host: M 46 years
Cell type: T cell CD4+
Tissue: metastatic site
Culture conditions: Direct Ex Vivo

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: VVRHCPHHERCSDSD
Assay category: TCell
Result: Positive
Host: M 46 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: VVRHCPHHERCSDSD
Assay category: TCell
Result: Negative
Host: M 46 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: VVRHCPHHERCSDSD
Assay category: TCell
Result: Positive
Host: M 46 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: VVRHCPHHERCSDSD
Assay category: TCell
Result: Negative
Host: M 46 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: VVRHCPHHERCSDSD
Assay category: TCell
Result: Positive
Host: M 46 years
Cell type: tumor infiltrating lymphocyte
Tissue: metastatic site
Culture conditions: Direct Ex Vivo

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: QHMTEVVRHCPHHER
Assay category: TCell
Result: Positive
Host: M 46 years
Cell type: T cell CD4+
Tissue: metastatic site
Culture conditions: Direct Ex Vivo

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: QHMTEVVRHCPHHER
Assay category: TCell
Result: Negative
Host: M 46 years
Cell type: T cell CD4+
Tissue: metastatic site
Culture conditions: Direct Ex Vivo

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: QHMTEVVRHCPHHER
Assay category: TCell
Result: Negative
Host: M 46 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: QHMTEVVRHCPHHER
Assay category: TCell
Result: Positive
Host: M 46 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: QHMTEVVRHCPHHER
Assay category: TCell
Result: Negative
Host: M 46 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: QHMTEVVRHCPHHER
Assay category: TCell
Result: Positive
Host: M 46 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R175H
Chemical type: Peptide, no natural source
Sequence: QHMTEVVRHCPHHER
Assay category: TCell
Result: Positive
Host: M 46 years
Cell type: tumor infiltrating lymphocyte
Tissue: metastatic site
Culture conditions: Direct Ex Vivo

Epitope: TP53 Y220C
Chemical type: Peptide, no natural source
Sequence: NTFRHSVVVPCEPPE
Assay category: TCell
Result: Positive
Host: F 39 years
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: TP53 Y220C
Chemical type: Peptide, no natural source
Sequence: NTFRHSVVVPCEPPE
Assay category: TCell
Result: Negative
Host: F 39 years
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: TP53 G245S
Chemical type: Peptide, no natural source
Sequence: HYNYMCNSSCMGSMN
Assay category: TCell
Result: Negative
Host: F 58 years
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: TP53 G245S
Chemical type: Peptide, no natural source
Sequence: HYNYMCNSSCMGSMN
Assay category: TCell
Result: Positive
Host: F 58 years
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248Q
Chemical type: Peptide, no natural source
Sequence: YMCNSSCMGGMNQRPILTIITLEDS
Assay category: TCell
Result: Positive
Host: F 69 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248Q
Chemical type: Peptide, no natural source
Sequence: YMCNSSCMGGMNQRPILTIITLEDS
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248Q
Chemical type: Peptide, no natural source
Sequence: YMCNSSCMGGMNQRPILTIITLEDS
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: tumor infiltrating lymphocyte
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248Q
Chemical type: Peptide, no natural source
Sequence: YMCNSSCMGGMNQRPILTIITLEDS
Assay category: TCell
Result: Positive
Host: F 69 years
Cell type: tumor infiltrating lymphocyte
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248Q
Chemical type: Peptide, no natural source
Sequence: YMCNSSCMGGMNQRPILTIITLEDS
Assay category: TCell
Result: Positive
Host: F 69 years
Cell type: T cell CD4+
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248Q
Chemical type: Peptide, no natural source
Sequence: YMCNSSCMGGMNQRPILTIITLEDS
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD4+
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248Q
Chemical type: Peptide, no natural source
Sequence: YMCNSSCMGGMNQRPILTIITLEDS
Assay category: TCell
Result: Positive
Host: F 69 years
Cell type: tumor infiltrating lymphocyte
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248Q
Chemical type: Peptide, no natural source
Sequence: YMCNSSCMGGMNQRPILTIITLEDS
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: tumor infiltrating lymphocyte
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248W
Chemical type: Peptide, no natural source
Sequence: SSCMGGMNWR
Assay category: TCell
Result: Negative
Host: F 41 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248W
Chemical type: Peptide, no natural source
Sequence: SSCMGGMNWR
Assay category: TCell
Result: Positive
Host: F 41 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R248W
Chemical type: Peptide, no natural source
Sequence: SSCMGGMNWR
Assay category: TCell
Result: Positive
Host: F 41 years
Cell type: tumor infiltrating lymphocyte
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248W
Chemical type: Peptide, no natural source
Sequence: SSCMGGMNWR
Assay category: TCell
Result: Positive
Host: F 41 years
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248W
Chemical type: Peptide, no natural source
Sequence: SSCMGGMNWR
Assay category: TCell
Result: Negative
Host: F 41 years
Cell type: tumor infiltrating lymphocyte
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248W
Chemical type: Peptide, no natural source
Sequence: SSCMGGMNWR
Assay category: TCell
Result: Positive
Host: F 41 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R248W
Chemical type: Peptide, no natural source
Sequence: SSCMGGMNWR
Assay category: TCell
Result: Negative
Host: F 41 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R248W
Chemical type: Peptide, no natural source
Sequence: SCMGGMNWRPILTII
Assay category: TCell
Result: Positive
Host: M 49 years
Cell type: T cell CD4+
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248W
Chemical type: Peptide, no natural source
Sequence: SCMGGMNWRPILTII
Assay category: TCell
Result: Negative
Host: M 49 years
Cell type: T cell CD4+
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248W
Chemical type: Peptide, no natural source
Sequence: SCMGGMNWRPILTII
Assay category: TCell
Result: Negative
Host: M 46 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R248W
Chemical type: Peptide, no natural source
Sequence: SCMGGMNWRPILTII
Assay category: TCell
Result: Positive
Host: M 46 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R248W
Chemical type: Peptide, no natural source
Sequence: SCMGGMNWRPILTII
Assay category: TCell
Result: Negative
Host: M 46 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R248W
Chemical type: Peptide, no natural source
Sequence: SCMGGMNWRPILTII
Assay category: TCell
Result: Positive
Host: M 46 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: TP53 R248W
Chemical type: Peptide, no natural source
Sequence: SCMGGMNWRPILTII
Assay category: TCell
Result: Positive
Host: M 49 years
Cell type: T cell CD4+
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248W
Chemical type: Peptide, no natural source
Sequence: SCMGGMNWRPILTII
Assay category: TCell
Result: Positive
Host: M 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R248W
Chemical type: Peptide, no natural source
Sequence: SCMGGMNWRPILTII
Assay category: TCell
Result: Negative
Host: M 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R282W
Chemical type: Peptide, no natural source
Sequence: FEVRVCACPGRDWRTEEENLRKKGE
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD4+
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R282W
Chemical type: Peptide, no natural source
Sequence: FEVRVCACPGRDWRTEEENLRKKGE
Assay category: TCell
Result: Positive
Host: F 69 years
Cell type: T cell CD4+
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R282W
Chemical type: Peptide, no natural source
Sequence: FEVRVCACPGRDWRTEEENLRKKGE
Assay category: TCell
Result: Positive
Host: F 69 years
Cell type: tumor infiltrating lymphocyte
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: TP53 R282W
Chemical type: Peptide, no natural source
Sequence: FEVRVCACPGRDWRTEEENLRKKGE
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: tumor infiltrating lymphocyte
Tissue: lung
Culture conditions: Direct Ex Vivo