Reference: Nikolaos Zacharakis; Harshini Chinnasamy; Mary Black; Hui Xu; Yong-Chen Lu; Zhili Zheng; Anna Pasetto; Michelle Langhan; Thomas Shelton; Todd Prickett; Jared Gartner; Li Jia; Katarzyna Trebska-McGowan; Robert P Somerville; Paul F Robbins; Steven A Rosenberg; Stephanie L Goff; Steven A Feldman. "Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer." Nature medicine (2018).

Epitope: LMNA : p.V517G
Chemical type: Peptide, no natural source
Sequence: ASSVTVTRSYRSGGGSGGGSFGDNL
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: TMEM53 : p.R34W
Chemical type: Peptide, no natural source
Sequence: NSPSPGGKEAETWQPVVILLGWGGC
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF239 : p.S359R
Chemical type: Peptide, no natural source
Sequence: YKCGECGKGFSQRSNLHIHRCIHTG
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF239 : p.S357R
Chemical type: Peptide, no natural source
Sequence: RPYKCGECGKGFRQSSNLHIHRCIH
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: SLC3A2 : p.K94T
Chemical type: Peptide, no natural source
Sequence: LLASSDPPALASTNAEVTGTMSQDT
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: T cell CD4+
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: SLC3A2 : p.K63T
Chemical type: Peptide, no natural source
Sequence: LLASSDPPALASTNAEVTVETGFHH
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: T cell CD4+
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: SLC3A2 : p.K94T
Chemical type: Peptide, no natural source
Sequence: LLASSDPPALASTNAEVTETGFHHV
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: T cell CD4+
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: C11orf24 : p.A143S
Chemical type: Peptide, no natural source
Sequence: SAPTTAASSTTVSSIAPTTAASSMT
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ATP2A2 : p.Y143C
Chemical type: Peptide, no natural source
Sequence: VHGGSWIRGAIYCFKIAVALAVAAI
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: KMT2D : p.S837P
Chemical type: Peptide, no natural source
Sequence: SPQPEESHLSPQPEEPCLSPRPEES
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: PABPC3 : p.R424Q
Chemical type: Peptide, no natural source
Sequence: NHAAYYPPSQIAQLRPSPRWTAQGA
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: LTK : p.R456H
Chemical type: Peptide, no natural source
Sequence: VRCVGLSLRATPHLILLELMSGGDM
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: BC108660 : p.S3R
Chemical type: Peptide, no natural source
Sequence: MARPSGSSEATGKPR
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: BC108660 : p.A10V
Chemical type: Peptide, no natural source
Sequence: MASPSGSSEVTGKPRGRDGRPR
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: TUBB3 : p.V4I
Chemical type: Peptide, no natural source
Sequence: MDSIRSGAFGHLFRPD
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: PCTP : p.S3A
Chemical type: Peptide, no natural source
Sequence: MDADYRKQWDQYVKE
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: PCTP : p.S75A
Chemical type: Peptide, no natural source
Sequence: CSPTLLADIYMDADYRKQWDQYVKE
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF506 : p.R333I
Chemical type: Peptide, no natural source
Sequence: AFNRSSNLTKHKIIHTGDVPYKCDE
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF486 : p.M367K
Chemical type: Peptide, no natural source
Sequence: CGKAFTRSSHLTKHKIIHTGEKPYK
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF708 : p.K226N
Chemical type: Peptide, no natural source
Sequence: KPYKCEECGKAFNQSSNLTNHKKIH
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF43 : p.C671S
Chemical type: Peptide, no natural source
Sequence: HKKIHTGEQPYKSEECGKAFNYSSH
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF43 : p.I605K
Chemical type: Peptide, no natural source
Sequence: AFKWSSTLTKHKKIHTGEKPYKCEE
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF43 : p.F528L
Chemical type: Peptide, no natural source
Sequence: LTTHKKIHTGEKLYKCEECGKAFTQ
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF479 : p.N348S
Chemical type: Peptide, no natural source
Sequence: KPYKCEECGKAFSVSSTLTQHKRIH
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF681 : p.Q504H
Chemical type: Peptide, no natural source
Sequence: PYQCEECGKAFNHSSHLTRHKRIHT
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF180 : p.A345S
Chemical type: Peptide, no natural source
Sequence: CGKSFSWSSHLVSHQRTHTGEKPYE
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF880 : p.Q406K
Chemical type: Peptide, no natural source
Sequence: CLTNHHRMHTGEKPYKCNECGR
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF880 : p.Q406K
Chemical type: Peptide, no natural source
Sequence: CLTNHHRMHTGEKPYKCNECGKAFR
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF880 : p.Q406R
Chemical type: Peptide, no natural source
Sequence: CLTNHHRMHTGERPYKCNECGR
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF880 : p.Q406R
Chemical type: Peptide, no natural source
Sequence: CLTNHHRMHTGERPYKCNECGKAFR
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF83 : p.H159N
Chemical type: Peptide, no natural source
Sequence: KPYKCNECGKVFNNMSHLAQHRRIH
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF600 : p.S539T
Chemical type: Peptide, no natural source
Sequence: KCNECSKTFSQRTYLHCHRRLHSGE
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF761 : p.C233S
Chemical type: Peptide, no natural source
Sequence: CGKTFSQTSSLTSHRRLHTGEKPYK
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF813 : p.V73I
Chemical type: Peptide, no natural source
Sequence: RPLVRRHPLHAIIDFILERNLSSVM
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF813 : p.R346H
Chemical type: Peptide, no natural source
Sequence: KTFSQTSSLTCHHRLHTGEKPFKCN
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF551 : p.S543R
Chemical type: Peptide, no natural source
Sequence: YECSECGKSFSQRASLIQHQRVHTG
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF814 : p.V365D
Chemical type: Peptide, no natural source
Sequence: ECGECGKSFSKYDSFSNHQRVHTGK
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF132 : p.S462C
Chemical type: Peptide, no natural source
Sequence: QKVHTGERPFECCECGRDFSQSSHL
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ALMS1 : p.L1218S
Chemical type: Peptide, no natural source
Sequence: ELPHFTEAGLKISRVPGPADQKTGI
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ANKRD36C : p.H946D
Chemical type: Peptide, no natural source
Sequence: KDSVLNIARGKKDGEKTRRVSSHKQ
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ANKRD36C : p.G943E
Chemical type: Peptide, no natural source
Sequence: SDEKDSVLNIAREKKHGEKTRRVSS
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: OPA1 : p.L355V
Chemical type: Peptide, no natural source
Sequence: PETISLNVKGPGVQRMVLVDLPGVI
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: FYCO1 : p.S1495R
Chemical type: Peptide, no natural source
Sequence: HLTVDRPVIYDGRDFL
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: MST1 : p.R108H
Chemical type: Peptide, no natural source
Sequence: PWTQHSPHTRLRHSGRCDLFQKKDY
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: MST1 : p.V19I
Chemical type: Peptide, no natural source
Sequence: HGLNTRPTRGCGILGAVTSSRRKPK
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: MST1 : p.R94H
Chemical type: Peptide, no natural source
Sequence: PWTQHSPHTRLRHSGRCDLFQKKGT
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: MST1 : p.T104S
Chemical type: Peptide, no natural source
Sequence: CQLLPWTQHSPHSRLRRSGRCDLFQ
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: MST1 : p.P13R
Chemical type: Peptide, no natural source
Sequence: MVANCCHGLNTRRTRGCGVLGAVTS
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: NIPBL : p.D598E
Chemical type: Peptide, no natural source
Sequence: GESRPETPKQKSEGHPETPKQKGDG
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: GPBP1 : p.H118R
Chemical type: Peptide, no natural source
Sequence: SSIFHAGKSQGLRENNIPDNETGRK
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: HLA-DRB1 : p.Y107F
Chemical type: Peptide, no natural source
Sequence: DILEQARAAVDTFCRHNYGVVESFT
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: HLA-DRB1 : p.Y107D
Chemical type: Peptide, no natural source
Sequence: DILEQARAAVDTDCRHNYGVVESFT
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: HLA-DQA2 : p.Y48F
Chemical type: Peptide, no natural source
Sequence: VNFYQSHGPSGQFTHEFDGDEEFYV
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: HLA-DQA2 : p.Q70K
Chemical type: Peptide, no natural source
Sequence: FYVDLETKETVWKLPMFSKFISFDP
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: CADPS2 : p.R1266H
Chemical type: Peptide, no natural source
Sequence: TLNSKTYDTVHRHLTVEEATASVSE
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: STK17A : p.D100H
Chemical type: Peptide, no natural source
Sequence: AAKFMRKRRKGQHCRMEIIHEIAVL
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: STK17A : p.E129D
Chemical type: Peptide, no natural source
Sequence: DNPWVINLHEVYDTASEMILVLEYA
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF12 : p.F395L
Chemical type: Peptide, no natural source
Sequence: GEKPYECYICGKLFSQMSYLTIHHR
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: CTSB : p.D159H
Chemical type: Peptide, no natural source
Sequence: GYNSYSVSNSEKHIMAEIYKNGPVE
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: PHF20L1 : p.E87V
Chemical type: Peptide, no natural source
Sequence: ERKWFKVPSKKEVTSTCIATPDVEK
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZC3H3 : p.A855T
Chemical type: Peptide, no natural source
Sequence: TPSSAALTAAAVTAPPHCPGGSASP
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: KIAA0368 : p.R189C
Chemical type: Peptide, no natural source
Sequence: MPYGYVLNESQSCQNSSSAQGSSSN
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: KIAA0368 : p.S186F
Chemical type: Peptide, no natural source
Sequence: VLLMPYGYVLNEFQSRQNSSSAQGS
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: SLC3A2 neoepitope
Chemical type: Peptide, no natural source
Sequence: DPPALASTNAEVT
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: KIAA0368 neoepitope
Chemical type: Peptide, no natural source
Sequence: MPYGYVLNEF
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: CADPS2 neoepitope
Chemical type: Peptide, no natural source
Sequence: TYDTVHRHL
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: CTSB neoepitope
Chemical type: Peptide, no natural source
Sequence: GYNSYSVSNSEKHIM
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: FAM21C : p.Y521S
Chemical type: Peptide from protein
Sequence: NKARAEKKVTLSSSKNLKPSSETKT
Position: 509-533
Source molecule (GenBank): Q641Q2.3
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: FLJ00385 : p.Y45F
Chemical type: Peptide from protein
Sequence: VHNAKTKPREEQFNSTFRVVSVLTV
Position: 301-325
Source molecule (GenBank): Q6MZU6.1
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: LRRC37A2 : p.H429P
Chemical type: Peptide from protein
Sequence: GTISENTNYNHPPEADSAGTAFNLG
Position: 1411-1435
Source molecule (GenBank): A0A0G2JMZ2.1
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: ZNF761 : p.Y454S
Chemical type: Peptide from protein
Sequence: CNECGKTFSRKSSLTCHHRLHTGEK
Position: 357-381
Source molecule (GenBank): Q6ZN06.2
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: RRBP1 : p.V472G
Chemical type: Peptide from protein
Sequence: KKAEGAQNQGKKGEGAQNQGKKAEG
Position: 310-334
Source molecule (GenBank): Q9P2E9.5
Assay category: TCell
Result: Negative
Host: F 49 years
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo