Reference: Davide Proietto; Beatrice Dallan; Eleonora Gallerani; Valentina Albanese; Sian Llewellyn-Lacey; David A Price; Victor Appay; Salvatore Pacifico; Antonella Caputo; Francesco Nicoli; Riccardo Gavioli. "Ageing Curtails the Diversity and Functionality of Nascent CD8<sup>+</sup> T Cell Responses against SARS-CoV-2." Vaccines (2023).

Epitope: SLV
Chemical type: Peptide from protein
Sequence: SLVKPSFYV
Position: 50-58
Source molecule (GenBank): P0DTC4.1
Assay category: TCell
Result: Positive
Host:  20-69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: SLV
Chemical type: Peptide from protein
Sequence: SLVKPSFYV
Position: 50-58
Source molecule (GenBank): P0DTC4.1
Assay category: TCell
Result: Positive
Host:  20-69 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SLV
Chemical type: Peptide from protein
Sequence: SLVKPSFYV
Position: 50-58
Source molecule (GenBank): P0DTC4.1
Assay category: MhcBinding
Result: Positive

Epitope: KLL
Chemical type: Peptide from protein
Sequence: KLLEQWNLV
Position: 15-23
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Host:  20-69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KLL
Chemical type: Peptide from protein
Sequence: KLLEQWNLV
Position: 15-23
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Host:  20-69 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KLL
Chemical type: Peptide from protein
Sequence: KLLEQWNLV
Position: 15-23
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Positive

Epitope: LLL
Chemical type: Peptide from protein
Sequence: LLLDRLNQL
Position: 222-230
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Host:  20-69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LLL
Chemical type: Peptide from protein
Sequence: LLLDRLNQL
Position: 222-230
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Host:  20-69 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LLL
Chemical type: Peptide from protein
Sequence: LLLDRLNQL
Position: 222-230
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive

Epitope: MLD
Chemical type: Peptide from protein
Sequence: MLDMYSVML
Position: 5291-5299
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Host:  20-69 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MLD
Chemical type: Peptide from protein
Sequence: MLDMYSVML
Position: 5291-5299
Source molecule (GenBank): P0DTD1.1
Assay category: MhcBinding
Result: Positive

Epitope: YLQ
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Host:  20-69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: YLQ
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Host:  20-69 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: YLQ
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: KIA
Chemical type: Peptide from protein
Sequence: KIADYNYKL
Position: 417-425
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Host:  20-69 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KIA
Chemical type: Peptide from protein
Sequence: KIADYNYKL
Position: 417-425
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive

Epitope: TLD
Chemical type: Peptide from protein
Sequence: TLDSKTQSL
Position: 109-117
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Host:  20-69 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TLD
Chemical type: Peptide from protein
Sequence: TLDSKTQSL
Position: 109-117
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: LLY
Chemical type: Peptide from protein
Sequence: LLYDANYFL
Position: 139-147
Source molecule (GenBank): P0DTC3.1
Assay category: TCell
Result: Positive
Host:  20-69 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LLY
Chemical type: Peptide from protein
Sequence: LLYDANYFL
Position: 139-147
Source molecule (GenBank): P0DTC3.1
Assay category: MhcBinding
Result: Positive

Epitope: HLV
Chemical type: Peptide from protein
Sequence: HLVDFQVTI
Position: 3-11
Source molecule (GenBank): P0DTC6.1
Assay category: TCell
Result: Positive
Host:  20-69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HLV
Chemical type: Peptide from protein
Sequence: HLVDFQVTI
Position: 3-11
Source molecule (GenBank): P0DTC6.1
Assay category: TCell
Result: Positive
Host:  20-69 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HLV
Chemical type: Peptide from protein
Sequence: HLVDFQVTI
Position: 3-11
Source molecule (GenBank): P0DTC6.1
Assay category: MhcBinding
Result: Positive