Reference: Diane Rottembourg; Cheri Deal; Marion Lambert; Roberto Mallone; Jean-Claude Carel; André Lacroix; Sophie Caillat-Zucman; Françoise le Deist. "21-Hydroxylase epitopes are targeted by CD8 T cells in autoimmune Addison's disease." Journal of autoimmunity (2010).

Epitope: 21-hydroxylase peptide 2 (11-30)
Chemical type: Peptide from protein
Sequence: LLAGARLLWNWWKLRSLHLP
Position: 11-30
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Host:  9-50 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 4 (31-50)
Chemical type: Peptide from protein
Sequence: PLAPGFLHLLQPDLPIYLLG
Position: 31-50
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Host:  9-50 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 4 (31-50)
Chemical type: Peptide from protein
Sequence: PLAPGFLHLLQPDLPIYLLG
Position: 31-50
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 5 (41-60)
Chemical type: Peptide from protein
Sequence: QPDLPIYLLGLTQKFGPIYR
Position: 41-60
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Host:  9-50 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 8 (71-90)
Chemical type: Peptide from protein
Sequence: LNSKRTIEEAMVKKWADFAG
Position: 71-90
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 9 (81-100)
Chemical type: Peptide from protein
Sequence: MVKKWADFAGRPEPLTYKLV
Position: 81-100
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Host:  9-50 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 9 (81-100)
Chemical type: Peptide from protein
Sequence: MVKKWADFAGRPEPLTYKLV
Position: 81-100
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 11 (101-120)
Chemical type: Peptide from protein
Sequence: SKNYPDLSLGDYSLLWKAHK
Position: 101-120
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 12 (111-130)
Chemical type: Peptide from protein
Sequence: DYSLLWKAHKKLTRSALLLG
Position: 111-130
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 13 (121-140)
Chemical type: Peptide from protein
Sequence: KLTRSALLLGIRDSMEPVVE
Position: 121-140
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 14 (131-150)
Chemical type: Peptide from protein
Sequence: IRDSMEPVVEQLTQEFCERM
Position: 131-150
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 14 (131-150)
Chemical type: Peptide from protein
Sequence: IRDSMEPVVEQLTQEFCERM
Position: 131-150
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Host:  9-50 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 16 (151-170)
Chemical type: Peptide from protein
Sequence: RAQPGTPVAIEEEFSLLTCS
Position: 151-170
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 16 (151-170)
Chemical type: Peptide from protein
Sequence: RAQPGTPVAIEEEFSLLTCS
Position: 151-170
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Host:  9-50 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 17 (161-180)
Chemical type: Peptide from protein
Sequence: EEEFSLLTCSIICYLTFGDK
Position: 161-180
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 17 (161-180)
Chemical type: Peptide from protein
Sequence: EEEFSLLTCSIICYLTFGDK
Position: 161-180
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Host:  9-50 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 18 (171-190)
Chemical type: Peptide from protein
Sequence: IICYLTFGDKIKDDNLMPAY
Position: 171-190
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 19 (181-200)
Chemical type: Peptide from protein
Sequence: IKDDNLMPAYYKCIQEVLKT
Position: 181-200
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 19 (181-200)
Chemical type: Peptide from protein
Sequence: IKDDNLMPAYYKCIQEVLKT
Position: 181-200
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Host:  9-50 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 20 (191-210)
Chemical type: Peptide from protein
Sequence: YKCIQEVLKTWSHWSIQIVD
Position: 191-210
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 20 (191-210)
Chemical type: Peptide from protein
Sequence: YKCIQEVLKTWSHWSIQIVD
Position: 191-210
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Host:  9-50 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 21 (201-220)
Chemical type: Peptide from protein
Sequence: WSHWSIQIVDVIPFLRFFPN
Position: 201-220
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 22 (211-230)
Chemical type: Peptide from protein
Sequence: VIPFLRFFPNPGLRRLKQAI
Position: 211-230
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 23 (221-240)
Chemical type: Peptide from protein
Sequence: PGLRRLKQAIEKRDHIVEMQ
Position: 221-240
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 24 (231-250)
Chemical type: Peptide from protein
Sequence: EKRDHIVEMQLRQHKESLVA
Position: 231-250
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 25 (241-260)
Chemical type: Peptide from protein
Sequence: LRQHKESLVAGQWRDMMDYM
Position: 241-260
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 26 (251-270)
Chemical type: Peptide from protein
Sequence: GQWRDMMDYMLQGVAQPSME
Position: 251-270
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 27 (261-280)
Chemical type: Peptide from protein
Sequence: LQGVAQPSMEEGSGQLLEGH
Position: 261-280
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 28 (271-290)
Chemical type: Peptide from protein
Sequence: EGSGQLLEGHVHMAAVDLLI
Position: 271-290
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 29 (281-300)
Chemical type: Peptide from protein
Sequence: VHMAAVDLLIGGTETTANTL
Position: 281-300
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 30 (2981-310)
Chemical type: Peptide from protein
Sequence: GGTETTANTLSWAVVFLLHH
Position: 291-310
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 31 (301-320)
Chemical type: Peptide from protein
Sequence: SWAVVFLLHHPEIQQRLQEE
Position: 301-320
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 32 (311-330)
Chemical type: Peptide from protein
Sequence: PEIQQRLQEELDHELGPGAS
Position: 311-330
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 33 (321-340)
Chemical type: Peptide from protein
Sequence: LDHELGPGASSSRVPYKDRA
Position: 321-340
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 34 (331-350)
Chemical type: Peptide from protein
Sequence: SSRVPYKDRARLPLLNATIA
Position: 331-350
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 36 (351-370)
Chemical type: Peptide from protein
Sequence: EVLRLRPVVPLALPHRTTRP
Position: 351-370
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 37 (361-380)
Chemical type: Peptide from protein
Sequence: LALPHRTTRPSSISGYDIPE
Position: 361-380
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 38 (371-390)
Chemical type: Peptide from protein
Sequence: SSISGYDIPEGTVIIPNLQG
Position: 371-390
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 39 (381-400)
Chemical type: Peptide from protein
Sequence: GTVIIPNLQGAHLDETVWER
Position: 381-400
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 40 (391-410)
Chemical type: Peptide from protein
Sequence: AHLDETVWERPHEFWPDRFL
Position: 391-410
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 41 (401-420)
Chemical type: Peptide from protein
Sequence: PHEFWPDRFLEPGKNSRALA
Position: 401-420
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 42 (411-430)
Chemical type: Peptide from protein
Sequence: EPGKNSRALAFGCGARVCLG
Position: 411-430
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 43 (421-440)
Chemical type: Peptide from protein
Sequence: FGCGARVCLGEPLARLELFV
Position: 421-440
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 44 (431-450)
Chemical type: Peptide from protein
Sequence: EPLARLELFVVLTRLLQAFT
Position: 431-450
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 44 (431-450)
Chemical type: Peptide from protein
Sequence: EPLARLELFVVLTRLLQAFT
Position: 431-450
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Host:  9-50 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 45 (441-460)
Chemical type: Peptide from protein
Sequence: VLTRLLQAFTLLPSGDALPS
Position: 441-460
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 46 (451-470)
Chemical type: Peptide from protein
Sequence: LLPSGDALPSLQPLPHCSVI
Position: 451-470
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 47 (461-480)
Chemical type: Peptide from protein
Sequence: LQPLPHCSVILKMQPFQVRL
Position: 461-480
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 48 (471-490)
Chemical type: Peptide from protein
Sequence: LKMQPFQVRLQPRGMGAHSP
Position: 471-490
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21-hydroxylase peptide 49 (481-500)
Chemical type: Peptide from protein
Sequence: QPRGMGAHSPGQNQ
Position: 481-494
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo