Reference: Daniela Weiskopf; Lauren E Yauch; Michael A Angelo; Daisy V John; Jason A Greenbaum; John Sidney; Ravi V Kolla; Aruna D De Silva; Aravinda M de Silva; Howard Grey; Bjoern Peters; Sujan Shresta; Alessandro Sette. "Insights into HLA-restricted T cell responses in a novel mouse model of dengue virus infection point toward new implications for vaccine design." Journal of immunology (Baltimore, Md. : 1950) (2011).

Epitope: NS3 1465-1473
Chemical type: Peptide from protein
Sequence: AAAWYLWEV
Position: 1463-1471
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3 1465-1473
Chemical type: Peptide from protein
Sequence: AAAWYLWEV
Position: 1463-1471
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 0.39

Epitope: C 53-67
Chemical type: Peptide from protein
Sequence: AFLRFLTIPPTAGIL
Position: 22-36
Source molecule (GenBank): AGW04190.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C 53-67
Chemical type: Peptide from protein
Sequence: AFLRFLTIPPTAGIL
Position: 22-36
Source molecule (GenBank): AGW04190.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 9.7

Epitope: NS3 1700-1709
Chemical type: Peptide from protein
Sequence: APTRVVAAEM
Position: 1697-1706
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3 1700-1709
Chemical type: Peptide from protein
Sequence: APTRVVAAEM
Position: 1697-1706
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 4.6

Epitope: NS4B 2315-2323
Chemical type: Peptide from protein
Sequence: ATVLMGLGK
Position: 2315-2323
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4B 2315-2323
Chemical type: Peptide from protein
Sequence: ATVLMGLGK
Position: 2315-2323
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 16.0

Epitope: NS2B 1383-1391
Chemical type: Peptide from protein
Sequence: GLLTVCYVL
Position: 1381-1389
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS2B 1383-1391
Chemical type: Peptide from protein
Sequence: GLLTVCYVL
Position: 1381-1389
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 6.0

Epitope: NS2A 1199-1213
Chemical type: Peptide from protein
Sequence: GVTYLALLAAFKVRP
Position: 1198-1212
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS2A 1199-1213
Chemical type: Peptide from protein
Sequence: GVTYLALLAAFKVRP
Position: 1198-1212
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 10.0

Epitope: NS4A 2205-2213
Chemical type: Peptide from protein
Sequence: IILEFFLIV
Position: 2202-2210
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4A 2205-2213
Chemical type: Peptide from protein
Sequence: IILEFFLIV
Position: 2202-2210
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 18.0

Epitope: NS2B 1355-1363
Chemical type: Peptide from protein
Sequence: IMAVGMVSI
Position: 1353-1361
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS2B 1355-1363
Chemical type: Peptide from protein
Sequence: IMAVGMVSI
Position: 1353-1361
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 1.9

Epitope: E 451-459
Chemical type: Peptide from protein
Sequence: ITEAELTGY
Position: 450-458
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E 451-459
Chemical type: Peptide from protein
Sequence: ITEAELTGY
Position: 450-458
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 25.0

Epitope: NS5 3058-3066
Chemical type: Peptide from protein
Sequence: KLAEAIFKL
Position: 3054-3062
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5 3058-3066
Chemical type: Peptide from protein
Sequence: KLAEAIFKL
Position: 3054-3062
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2.2

Epitope: NS2B 1450-1459
Chemical type: Peptide from protein
Sequence: LLVISGLFPV
Position: 1448-1457
Source molecule (GenBank): AGS49173.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS2B 1450-1459
Chemical type: Peptide from protein
Sequence: LLVISGLFPV
Position: 1448-1457
Source molecule (GenBank): AGS49173.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 26.0

Epitope: NS3 1682-1690
Chemical type: Peptide from protein
Sequence: LPAIVREAI
Position: 1679-1687
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3 1682-1690
Chemical type: Peptide from protein
Sequence: LPAIVREAI
Position: 1679-1687
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 6.5

Epitope: NS2A 1251-1259
Chemical type: Peptide from protein
Sequence: LTDALALGM
Position: 1250-1258
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS2A 1251-1259
Chemical type: Peptide from protein
Sequence: LTDALALGM
Position: 1250-1258
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 129.0

Epitope: NS2B 1356-1370
Chemical type: Peptide from protein
Sequence: MAVGMVSILASSLLK
Position: 1354-1368
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS2B 1356-1370
Chemical type: Peptide from protein
Sequence: MAVGMVSILASSLLK
Position: 1354-1368
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 34.0

Epitope: NS2A 1192-1200
Chemical type: Peptide from protein
Sequence: MTDDIGMGV
Position: 1191-1199
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS2A 1192-1200
Chemical type: Peptide from protein
Sequence: MTDDIGMGV
Position: 1191-1199
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 19.0

Epitope: E 631-639
Chemical type: Peptide from protein
Sequence: RLITVNPIV
Position: 630-638
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E 631-639
Chemical type: Peptide from protein
Sequence: RLITVNPIV
Position: 630-638
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2.8

Epitope: NS4B 2280-2289
Chemical type: Peptide from protein
Sequence: RPASAWTLYA
Position: 2276-2285
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4B 2280-2289
Chemical type: Peptide from protein
Sequence: RPASAWTLYA
Position: 2276-2285
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 7.4

Epitope: NS2A 1212-1221
Chemical type: Peptide from protein
Sequence: RPTFAAGLLL
Position: 1211-1220
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS2A 1212-1221
Chemical type: Peptide from protein
Sequence: RPTFAAGLLL
Position: 1211-1220
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 4.8

Epitope: NS5 3077-3085
Chemical type: Peptide from protein
Sequence: RPTPRGTVM
Position: 3073-3081
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5 3077-3085
Chemical type: Peptide from protein
Sequence: RPTPRGTVM
Position: 3073-3081
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 1.5

Epitope: NS5 3112-3121
Chemical type: Peptide from protein
Sequence: RQMEGEGVFK
Position: 3112-3121
Source molecule (GenBank): AGF87124.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5 3112-3121
Chemical type: Peptide from protein
Sequence: RQMEGEGVFK
Position: 3112-3121
Source molecule (GenBank): AGF87124.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 118.0

Epitope: NS1 1090-1099
Chemical type: Peptide from protein
Sequence: RSCTLPPLRY
Position: 1089-1098
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS1 1090-1099
Chemical type: Peptide from protein
Sequence: RSCTLPPLRY
Position: 1089-1098
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 5.9

Epitope: NS5 3283-3291
Chemical type: Peptide from protein
Sequence: RTTWSIHAK
Position: 3283-3291
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5 3283-3291
Chemical type: Peptide from protein
Sequence: RTTWSIHAK
Position: 3283-3291
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 83.0

Epitope: NS5 2646-2655
Chemical type: Peptide from protein
Sequence: SPNPTVEAGR
Position: 2642-2651
Source molecule (GenBank): AGS49173.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5 2646-2655
Chemical type: Peptide from protein
Sequence: SPNPTVEAGR
Position: 2642-2651
Source molecule (GenBank): AGS49173.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1332.0

Epitope: NS3 1509-1517
Chemical type: Peptide from protein
Sequence: SQIGAGVYK
Position: 1509-1517
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3 1509-1517
Chemical type: Peptide from protein
Sequence: SQIGAGVYK
Position: 1509-1517
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 33.0

Epitope: NS5 2966-2980
Chemical type: Peptide from protein
Sequence: SRAIWYMWLGARFLE
Position: 2962-2976
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5 2966-2980
Chemical type: Peptide from protein
Sequence: SRAIWYMWLGARFLE
Position: 2962-2976
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 17.0

Epitope: NS5 2608-2616
Chemical type: Peptide from protein
Sequence: STYGWNLVR
Position: 2608-2616
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5 2608-2616
Chemical type: Peptide from protein
Sequence: STYGWNLVR
Position: 2608-2616
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 22.0

Epitope: NS3 1742-1756
Chemical type: Peptide from protein
Sequence: TFTMRLLSPVRVPNY
Position: 1739-1753
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3 1742-1756
Chemical type: Peptide from protein
Sequence: TFTMRLLSPVRVPNY
Position: 1739-1753
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 1.5

Epitope: NS3 1978-1987
Chemical type: Peptide from protein
Sequence: TPEGIIPSMF
Position: 1975-1984
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3 1978-1987
Chemical type: Peptide from protein
Sequence: TPEGIIPSMF
Position: 1975-1984
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 589.0

Epitope: NS4B 2296-2305
Chemical type: Peptide from protein
Sequence: TPMLRHSI
Position: 2292-2299
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4B 2296-2305
Chemical type: Peptide from protein
Sequence: TPMLRHSI
Position: 2292-2299
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 1.1

Epitope: NS5 2885-2894
Chemical type: Peptide from protein
Sequence: TPRMCTREEF
Position: 2881-2890
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5 2885-2894
Chemical type: Peptide from protein
Sequence: TPRMCTREEF
Position: 2881-2890
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 13.0

Epitope: NS5 3079-3087
Chemical type: Peptide from protein
Sequence: TVMDIISRR
Position: 3079-3087
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5 3079-3087
Chemical type: Peptide from protein
Sequence: TVMDIISRR
Position: 3079-3087
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 71.0

Epitope: NS4B 2399-2407
Chemical type: Peptide from protein
Sequence: VIDLDPIPY
Position: 2395-2403
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4B 2399-2407
Chemical type: Peptide from protein
Sequence: VIDLDPIPY
Position: 2395-2403
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 17.0

Epitope: NS3 1753-1761
Chemical type: Peptide from protein
Sequence: VPNYNLIIM
Position: 1750-1758
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3 1753-1761
Chemical type: Peptide from protein
Sequence: VPNYNLIIM
Position: 1750-1758
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 43.0

Epitope: NS3 1681-1689
Chemical type: Peptide from protein
Sequence: YLPAIVREA
Position: 1678-1686
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3 1681-1689
Chemical type: Peptide from protein
Sequence: YLPAIVREA
Position: 1678-1686
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 18.0

Epitope: NS5 3375-3383
Chemical type: Peptide from protein
Sequence: YTDYMPSMK
Position: 3370-3378
Source molecule (GenBank): AGO67248.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5 3375-3383
Chemical type: Peptide from protein
Sequence: YTDYMPSMK
Position: 3370-3378
Source molecule (GenBank): AGO67248.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 37.0