Reference: Vamseedhar Rayaprolu; Benjamin O Fulton; Ashique Rafique; Emilia Arturo; Dewight Williams; Chitra Hariharan; Heather Callaway; Amar Parvate; Sharon L Schendel; Diptiben Parekh; Sean Hui; Kelly Shaffer; Kristen E Pascal; Elzbieta Wloga; Stephanie Giordano; Nicole Negron; Min Ni; Richard Copin; Gurinder S Atwal; Matthew Franklin; Ruth Mabel Boytz; Callie Donahue; Robert Davey; Alina Baum; Christos A Kyratsous; Erica Ollmann Saphire. "Structure of the Inmazeb cocktail and resistance to Ebola virus escape." Cell host & microbe (2023).

Epitope: Epitope of Fab REGN3479 on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: V: A525, I527, G528, L529, A530, F535, G536, P537; X: A507, Q560, E564, Q567
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab REGN3479 on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: V: A525, I527, G528, L529, A530, F535, G536, P537; X: A507, Q560, E564, Q567
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab REGN3479 on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: V: A525, I527, G528, L529, A530, F535, G536, P537; X: A507, Q560, E564, Q567
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab REGN3479 on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: V: A525, I527, G528, L529, A530, F535, G536, P537; X: A507, Q560, E564, Q567
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab REGN3479 on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: V: A525, I527, G528, L529, A530, F535, G536, P537; X: A507, Q560, E564, Q567
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab REGN3479 on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: V: A525, I527, G528, L529, A530, F535, G536, P537; X: A507, Q560, E564, Q567
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive
Quantitative measurement: 66100.0

Epitope: Epitope of Fab REGN3479 on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: V: A525, I527, G528, L529, A530, F535, G536, P537; X: A507, Q560, E564, Q567
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab REGN3479 on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: V: A525, I527, G528, L529, A530, F535, G536, P537; X: A507, Q560, E564, Q567
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab REGN3479 on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: V: A525, I527, G528, L529, A530, F535, G536, P537; X: A507, Q560, E564, Q567
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab REGN3479 on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: V: A525, I527, G528, L529, A530, F535, G536, P537; X: A507, Q560, E564, Q567
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000108

Epitope: Epitope of Fab REGN3479 on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: V: A525, I527, G528, L529, A530, F535, G536, P537; X: A507, Q560, E564, Q567
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.64

Epitope: Epitope of Fab REGN3471 on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: E112, K114, K115, P116, D117, G118, S119, G143, T144, P146, R172, Q221, A222, T223, G224, E229, E231, L233, N238, L239, Y241, N268, T269, T270, G271, K272, I274
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of Fab REGN3471 on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: E112, K114, K115, P116, D117, G118, S119, G143, T144, P146, R172, Q221, A222, T223, G224, E229, E231, L233, N238, L239, Y241, N268, T269, T270, G271, K272, I274
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive
Quantitative measurement: 36800.0

Epitope: Epitope of Fab REGN3471 on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: E112, K114, K115, P116, D117, G118, S119, G143, T144, P146, R172, Q221, A222, T223, G224, E229, E231, L233, N238, L239, Y241, N268, T269, T270, G271, K272, I274
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.42

Epitope: Epitope of Fab REGN3471 on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: E112, K114, K115, P116, D117, G118, S119, G143, T144, P146, R172, Q221, A222, T223, G224, E229, E231, L233, N238, L239, Y241, N268, T269, T270, G271, K272, I274
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000163

Epitope: Epitope of Fab REGN3471 on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: E112, K114, K115, P116, D117, G118, S119, G143, T144, P146, R172, Q221, A222, T223, G224, E229, E231, L233, N238, L239, Y241, N268, T269, T270, G271, K272, I274
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab REGN3470 on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: R247, T262, S263, K265, K276, V277, N278, P279, E280, I281, D282, R302, E304, L306, S307, F308, T309, V310
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab REGN3470 on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: R247, T262, S263, K265, K276, V277, N278, P279, E280, I281, D282, R302, E304, L306, S307, F308, T309, V310
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.19

Epitope: Epitope of Fab REGN3470 on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: R247, T262, S263, K265, K276, V277, N278, P279, E280, I281, D282, R302, E304, L306, S307, F308, T309, V310
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000095

Epitope: Epitope of Fab REGN3470 on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: R247, T262, S263, K265, K276, V277, N278, P279, E280, I281, D282, R302, E304, L306, S307, F308, T309, V310
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive
Quantitative measurement: 79500.0

Epitope: Epitope of Fab REGN3470 on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: R247, T262, S263, K265, K276, V277, N278, P279, E280, I281, D282, R302, E304, L306, S307, F308, T309, V310
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb114 on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: K114, K115, P116, D117, G118, E120, S142, G143, T144, G145, P146, Q221, T223, G224, T227, E231, L233, Y241, T269
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.313

Epitope: Epitope of mAb114 on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: K114, K115, P116, D117, G118, E120, S142, G143, T144, G145, P146, Q221, T223, G224, T227, E231, L233, Y241, T269
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb114 on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: K114, K115, P116, D117, G118, E120, S142, G143, T144, G145, P146, Q221, T223, G224, T227, E231, L233, Y241, T269
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb114 on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: K114, K115, P116, D117, G118, E120, S142, G143, T144, G145, P146, Q221, T223, G224, T227, E231, L233, Y241, T269
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000308

Epitope: Epitope of mAb114 on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: K114, K115, P116, D117, G118, E120, S142, G143, T144, G145, P146, Q221, T223, G224, T227, E231, L233, Y241, T269
Source molecule (GenBank): Q05320.1
Assay category: BCell
Result: Positive
Quantitative measurement: 98400.0