Reference: Jenna J Guthmiller; Julianna Han; Henry A Utset; Lei Li; Linda Yu-Ling Lan; Carole Henry; Christopher T Stamper; Meagan McMahon; George O'Dell; Monica L Fernández-Quintero; Alec W Freyn; Fatima Amanat; Olivia Stovicek; Lauren Gentles; Sara T Richey; Alba Torrents de la Peña; Victoria Rosado; Haley L Dugan; Nai-Ying Zheng; Micah E Tepora; Dalia J Bitar; Siriruk Changrob; Shirin Strohmeier; Min Huang; Adolfo García-Sastre; Klaus R Liedl; Jesse D Bloom; Raffael Nachbagauer; Peter Palese; Florian Krammer; Lynda Coughlan; Andrew B Ward; Patrick C Wilson. "Broadly neutralizing antibodies target a haemagglutinin anchor epitope." Nature (2022).

Epitope: Epitope of 222-1C06 Fab on H1 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: W358, T359, V362, H369, Q371, N372, E373, G375, S376, Y378, K475, E483, Y485
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 222-1C06 Fab on H1 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: W358, T359, V362, H369, Q371, N372, E373, G375, S376, Y378, K475, E483, Y485
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.0

Epitope: Epitope of 222-1C06 Fab on H1 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: W358, T359, V362, H369, Q371, N372, E373, G375, S376, Y378, K475, E483, Y485
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.0

Epitope: Epitope of 222-1C06 Fab on H1 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: W358, T359, V362, H369, Q371, N372, E373, G375, S376, Y378, K475, E483, Y485
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.0

Epitope: Epitope of 222-1C06 Fab on H1 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: W358, T359, V362, H369, Q371, N372, E373, G375, S376, Y378, K475, E483, Y485
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 222-1C06 Fab on H1 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: W358, T359, V362, H369, Q371, N372, E373, G375, S376, Y378, K475, E483, Y485
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.0

Epitope: Epitope of 222-1C06 Fab on H1 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: W358, T359, V362, H369, Q371, N372, E373, G375, S376, Y378, K475, E483, Y485
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.0

Epitope: Epitope of 222-1C06 Fab on H1 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: W358, T359, V362, H369, Q371, N372, E373, G375, S376, Y378, K475, E483, Y485
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.0

Epitope: Epitope of 222-1C06 Fab on H1 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: W358, T359, V362, H369, Q371, N372, E373, G375, S376, Y378, K475, E483, Y485
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.0

Epitope: Epitope of 222-1C06 Fab on H1 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: W358, T359, V362, H369, Q371, N372, E373, G375, S376, Y378, K475, E483, Y485
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 222-1C06 Fab on H1 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: W358, T359, V362, H369, Q371, N372, E373, G375, S376, Y378, K475, E483, Y485
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 045-09 2B05 Fab on H1 HA
Chemical type: Discontinuous protein residues
Discontinuous residues: E85, E129, R130, F131, E132, I133, T137, P135, S138, Y182, N184, D185, K186, G187, K188, V190, Y270, A273
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Central stalk epitope residue I385
Chemical type: Discontinuous protein residues
Discontinuous residues: I400
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Central stalk epitope residue Q371
Chemical type: Discontinuous protein residues
Discontinuous residues: Q386
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Central stalk epitope residue Q371
Chemical type: Discontinuous protein residues
Discontinuous residues: Q386
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Central stalk epitope residue Q371
Chemical type: Discontinuous protein residues
Discontinuous residues: Q386
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Central stalk epitope residues D375, T378
Chemical type: Discontinuous protein residues
Discontinuous residues: D390, T393
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Central stalk epitope residues K368, Q371, D375, T378, E386
Chemical type: Discontinuous protein residues
Discontinuous residues: K383, Q386, D390, T393, E401
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Central stalk epitope residues K368, Q371, D375, T378, E386
Chemical type: Discontinuous protein residues
Discontinuous residues: K383, Q386, D390, T393, E401
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Central stalk epitope residues K368, Q371, D375, T378, E386
Chemical type: Discontinuous protein residues
Discontinuous residues: K383, Q386, D390, T393, E401
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Central stalk epitope residue T378
Chemical type: Discontinuous protein residues
Discontinuous residues: T393
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Central stalk epitope residue T378
Chemical type: Discontinuous protein residues
Discontinuous residues: T393
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Central stalk epitope residue T378
Chemical type: Discontinuous protein residues
Discontinuous residues: T393
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Central stalk epitope residues D375, T378, I385
Chemical type: Discontinuous protein residues
Discontinuous residues: D390, T393, I400
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Anchor epitope residue A373
Chemical type: Discontinuous protein residues
Discontinuous residues: A388
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.0

Epitope: Anchor epitope residue A373
Chemical type: Discontinuous protein residues
Discontinuous residues: A388
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.0

Epitope: Anchor epitope residue A373
Chemical type: Discontinuous protein residues
Discontinuous residues: A388
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.0

Epitope: Anchor epitope residue A373
Chemical type: Discontinuous protein residues
Discontinuous residues: A388
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.0

Epitope: Anchor epitope residue A373
Chemical type: Discontinuous protein residues
Discontinuous residues: A388
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.0

Epitope: Anchor epitope residue A373
Chemical type: Discontinuous protein residues
Discontinuous residues: A388
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.0

Epitope: Anchor epitope residue A373
Chemical type: Discontinuous protein residues
Discontinuous residues: A388
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive

Epitope: Anchor epitope residue A373
Chemical type: Discontinuous protein residues
Discontinuous residues: A388
Source molecule (GenBank): ACP41953.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.0