Reference: Yoshito Tomimaru; Sasmita Mishra; Howard Safran; Kevin P Charpentier; William Martin; Anne S De Groot; Stephen H Gregory; Jack R Wands. "Aspartate-β-hydroxylase induces epitope-specific T cell responses in hepatocellular carcinoma." Vaccine (2015).

Epitope: p103
Chemical type: Peptide from protein
Sequence: AKVLLGLKERSTSEP
Position: 103-117
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p103
Chemical type: Peptide from protein
Sequence: AKVLLGLKERSTSEP
Position: 103-117
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p103
Chemical type: Peptide from protein
Sequence: AKVLLGLKERSTSEP
Position: 103-117
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p148
Chemical type: Peptide from protein
Sequence: KEQIQSLLHEMVHAEHVEG
Position: 148-166
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p148
Chemical type: Peptide from protein
Sequence: KEQIQSLLHEMVHAEHVEG
Position: 148-166
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p148
Chemical type: Peptide from protein
Sequence: KEQIQSLLHEMVHAEHVEG
Position: 148-166
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p322
Chemical type: Peptide from protein
Sequence: QKAKVKKKKPKLLNKF
Position: 322-337
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p322
Chemical type: Peptide from protein
Sequence: QKAKVKKKKPKLLNKF
Position: 322-337
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p322
Chemical type: Peptide from protein
Sequence: QKAKVKKKKPKLLNKF
Position: 322-337
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p415
Chemical type: Peptide from protein
Sequence: PADLLKLSLKRRSDRQQF
Position: 415-432
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p415
Chemical type: Peptide from protein
Sequence: PADLLKLSLKRRSDRQQF
Position: 415-432
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p415
Chemical type: Peptide from protein
Sequence: PADLLKLSLKRRSDRQQF
Position: 415-432
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p427
Chemical type: Peptide from protein
Sequence: SDRQQFLGHMRGSLLTLQ
Position: 427-444
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p427
Chemical type: Peptide from protein
Sequence: SDRQQFLGHMRGSLLTLQ
Position: 427-444
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p427
Chemical type: Peptide from protein
Sequence: SDRQQFLGHMRGSLLTLQ
Position: 427-444
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p437
Chemical type: Peptide from protein
Sequence: RGSLLTLQRLVQLFPN
Position: 437-452
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p437
Chemical type: Peptide from protein
Sequence: RGSLLTLQRLVQLFPN
Position: 437-452
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p437
Chemical type: Peptide from protein
Sequence: RGSLLTLQRLVQLFPN
Position: 437-452
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p443
Chemical type: Peptide from protein
Sequence: LQRLVQLFPNDTSLKN
Position: 443-458
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p443
Chemical type: Peptide from protein
Sequence: LQRLVQLFPNDTSLKN
Position: 443-458
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p443
Chemical type: Peptide from protein
Sequence: LQRLVQLFPNDTSLKN
Position: 443-458
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p492
Chemical type: Peptide from protein
Sequence: VHYGFILKAQNKIAESIP
Position: 492-509
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p492
Chemical type: Peptide from protein
Sequence: VHYGFILKAQNKIAESIP
Position: 492-509
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p492
Chemical type: Peptide from protein
Sequence: VHYGFILKAQNKIAESIP
Position: 492-509
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p557
Chemical type: Peptide from protein
Sequence: ASVWQRSLYNVNGLKAQPWW
Position: 557-576
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p557
Chemical type: Peptide from protein
Sequence: ASVWQRSLYNVNGLKAQPWW
Position: 557-576
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p557
Chemical type: Peptide from protein
Sequence: ASVWQRSLYNVNGLKAQPWW
Position: 557-576
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p581
Chemical type: Peptide from protein
Sequence: TGYTELVKSLERNWKLI
Position: 581-597
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p581
Chemical type: Peptide from protein
Sequence: TGYTELVKSLERNWKLI
Position: 581-597
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p581
Chemical type: Peptide from protein
Sequence: TGYTELVKSLERNWKLI
Position: 581-597
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p588
Chemical type: Peptide from protein
Sequence: KSLERNWKLIRDEGLAVMDK
Position: 588-607
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p588
Chemical type: Peptide from protein
Sequence: KSLERNWKLIRDEGLAVMDK
Position: 588-607
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p588
Chemical type: Peptide from protein
Sequence: KSLERNWKLIRDEGLAVMDK
Position: 588-607
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p725
Chemical type: Peptide from protein
Sequence: HEVWQDASSFRLIF
Position: 725-738
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p725
Chemical type: Peptide from protein
Sequence: HEVWQDASSFRLIF
Position: 725-738
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p725
Chemical type: Peptide from protein
Sequence: HEVWQDASSFRLIF
Position: 725-738
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p731
Chemical type: Peptide from protein
Sequence: ASSFRLIFIVDVWHPEL
Position: 731-747
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p731
Chemical type: Peptide from protein
Sequence: ASSFRLIFIVDVWHPEL
Position: 731-747
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p731
Chemical type: Peptide from protein
Sequence: ASSFRLIFIVDVWHPEL
Position: 731-747
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p740
Chemical type: Peptide from protein
Sequence: VDVWHPELTPQQRRSLPAI
Position: 740-758
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p740
Chemical type: Peptide from protein
Sequence: VDVWHPELTPQQRRSLPAI
Position: 740-758
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p740
Chemical type: Peptide from protein
Sequence: VDVWHPELTPQQRRSLPAI
Position: 740-758
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH48 (1)
Chemical type: Peptide from protein
Sequence: GLSGTSFFT
Position: 48-56
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH53 (2)
Chemical type: Peptide from protein
Sequence: SFFTWFMVI
Position: 53-61
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Negative
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH58 (3)
Chemical type: Peptide from protein
Sequence: FMVIALLGV
Position: 58-66
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH62 (4)
Chemical type: Peptide from protein
Sequence: ALLGVWTSV
Position: 62-70
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH72 (5)
Chemical type: Peptide from protein
Sequence: VVWFDLVDY
Position: 72-80
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH79 (6)
Chemical type: Peptide from protein
Sequence: DYEEVLGKL
Position: 79-87
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH81 (7)
Chemical type: Peptide from protein
Sequence: EEVLGKLGI
Position: 81-89
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH252 (8)
Chemical type: Peptide from protein
Sequence: TDDVTYQVY
Position: 252-260
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH258 (9)
Chemical type: Peptide from protein
Sequence: QVYEEQAVY
Position: 258-266
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH261 (10)
Chemical type: Peptide from protein
Sequence: EEQAVYEPL
Position: 261-269
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH371 (11)
Chemical type: Peptide from protein
Sequence: YPQSPRARY
Position: 371-379
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH374 (12)
Chemical type: Peptide from protein
Sequence: SPRARYGKA
Position: 374-382
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH411 (14)
Chemical type: Peptide from protein
Sequence: LPDVPADLL
Position: 411-419
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH475 (15)
Chemical type: Peptide from protein
Sequence: KVYEEVLSV
Position: 475-483
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH478 (16)
Chemical type: Peptide from protein
Sequence: EEVLSVTPN
Position: 478-486
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH484 (17)
Chemical type: Peptide from protein
Sequence: TPNDGFAKV
Position: 484-492
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH488 (18)
Chemical type: Peptide from protein
Sequence: GFAKVHYGF
Position: 488-496
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH491 (19)
Chemical type: Peptide from protein
Sequence: KVHYGFILK
Position: 491-499
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH503 (20)
Chemical type: Peptide from protein
Sequence: KIAESIPYL
Position: 503-511
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH537 (22)
Chemical type: Peptide from protein
Sequence: RVGNKEAYK
Position: 537-545
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Negative
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH557 (23)
Chemical type: Peptide from protein
Sequence: ASVWQRSLY
Position: 557-565
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH563 (24)
Chemical type: Peptide from protein
Sequence: SLYNVNGLK
Position: 563-571
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH582 (25)
Chemical type: Peptide from protein
Sequence: GYTELVKSL
Position: 582-590
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH611 (26)
Chemical type: Peptide from protein
Sequence: LFLPEDENL
Position: 611-619
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH681 (27)
Chemical type: Peptide from protein
Sequence: GPTNCRLRM
Position: 681-689
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH693 (28)
Chemical type: Peptide from protein
Sequence: LVIPKEGCK
Position: 693-701
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH701 (29)
Chemical type: Peptide from protein
Sequence: KIRCANETR
Position: 701-709
Source molecule (GenBank): AAB50779.1
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ASPH711 (30)
Chemical type: Peptide from protein
Sequence: WEEGKVLIF
Position: 711-719
Source molecule (GenBank): Q12797.3
Assay category: TCell
Result: Positive
Host:  57-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated