Reference: Yuling Wang; Lu Yang; Kang Tang; Yusi Zhang; Chunmei Zhang; Yun Zhang; Boquan Jin; Yuan Zhang; Ran Zhuang; Ying Ma. "Ad5-nCoV Vaccination Could Induce HLA-E Restricted CD8<sup>+</sup> T Cell Responses Specific for Epitopes on Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein." Viruses (2023).

Epitope: S1
Chemical type: Peptide from protein
Sequence: RFDNPVLPF
Position: 78-86
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S1
Chemical type: Peptide from protein
Sequence: RFDNPVLPF
Position: 78-86
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S2
Chemical type: Peptide from protein
Sequence: TLDSKTQSL
Position: 109-117
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S2
Chemical type: Peptide from protein
Sequence: TLDSKTQSL
Position: 109-117
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S3
Chemical type: Peptide from protein
Sequence: VSQPFLMDL
Position: 171-179
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S3
Chemical type: Peptide from protein
Sequence: VSQPFLMDL
Position: 171-179
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S4
Chemical type: Peptide from protein
Sequence: KIYSKHTPI
Position: 202-210
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S4
Chemical type: Peptide from protein
Sequence: KIYSKHTPI
Position: 202-210
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S5
Chemical type: Peptide from protein
Sequence: YSKHTPINL
Position: 204-212
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S5
Chemical type: Peptide from protein
Sequence: YSKHTPINL
Position: 204-212
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S6
Chemical type: Peptide from protein
Sequence: INITRFQTL
Position: 233-241
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S6
Chemical type: Peptide from protein
Sequence: INITRFQTL
Position: 233-241
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S7
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S7
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S7
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S7
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S7
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S7
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive

Epitope: S7
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive

Epitope: S8
Chemical type: Peptide from protein
Sequence: VRFPNITNL
Position: 327-335
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S8
Chemical type: Peptide from protein
Sequence: VRFPNITNL
Position: 327-335
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S9
Chemical type: Peptide from protein
Sequence: VSPTKLNDL
Position: 382-390
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S9
Chemical type: Peptide from protein
Sequence: VSPTKLNDL
Position: 382-390
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S10
Chemical type: Peptide from protein
Sequence: KIADYNYKL
Position: 417-425
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S10
Chemical type: Peptide from protein
Sequence: KIADYNYKL
Position: 417-425
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive

Epitope: S11
Chemical type: Peptide from protein
Sequence: YQPYRVVVL
Position: 505-513
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S11
Chemical type: Peptide from protein
Sequence: YQPYRVVVL
Position: 505-513
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S12
Chemical type: Peptide from protein
Sequence: CGPKKSTNL
Position: 525-533
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S12
Chemical type: Peptide from protein
Sequence: CGPKKSTNL
Position: 525-533
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S13
Chemical type: Peptide from protein
Sequence: VRDPQTLEI
Position: 576-584
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S13
Chemical type: Peptide from protein
Sequence: VRDPQTLEI
Position: 576-584
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S13
Chemical type: Peptide from protein
Sequence: VRDPQTLEI
Position: 576-584
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive

Epitope: S13
Chemical type: Peptide from protein
Sequence: VRDPQTLEI
Position: 576-584
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive

Epitope: S14
Chemical type: Peptide from protein
Sequence: ILDITPCSF
Position: 584-592
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S14
Chemical type: Peptide from protein
Sequence: ILDITPCSF
Position: 584-592
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S15
Chemical type: Peptide from protein
Sequence: KQIYKTPPI
Position: 786-794
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S15
Chemical type: Peptide from protein
Sequence: KQIYKTPPI
Position: 786-794
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive

Epitope: S16
Chemical type: Peptide from protein
Sequence: LQIPFAMQM
Position: 894-902
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S16
Chemical type: Peptide from protein
Sequence: LQIPFAMQM
Position: 894-902
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S17
Chemical type: Peptide from protein
Sequence: VLYENQKLI
Position: 915-923
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S17
Chemical type: Peptide from protein
Sequence: VLYENQKLI
Position: 915-923
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S18
Chemical type: Peptide from protein
Sequence: VVNQNAQAL
Position: 951-959
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S18
Chemical type: Peptide from protein
Sequence: VVNQNAQAL
Position: 951-959
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S19
Chemical type: Peptide from protein
Sequence: ALNTLVKQL
Position: 958-966
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S19
Chemical type: Peptide from protein
Sequence: ALNTLVKQL
Position: 958-966
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S19
Chemical type: Peptide from protein
Sequence: ALNTLVKQL
Position: 958-966
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S19
Chemical type: Peptide from protein
Sequence: ALNTLVKQL
Position: 958-966
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S19
Chemical type: Peptide from protein
Sequence: ALNTLVKQL
Position: 958-966
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S19
Chemical type: Peptide from protein
Sequence: ALNTLVKQL
Position: 958-966
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive

Epitope: S19
Chemical type: Peptide from protein
Sequence: ALNTLVKQL
Position: 958-966
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive

Epitope: S20
Chemical type: Peptide from protein
Sequence: VLNDILSRL
Position: 976-984
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S20
Chemical type: Peptide from protein
Sequence: VLNDILSRL
Position: 976-984
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S21
Chemical type: Peptide from protein
Sequence: LQTYVTQQL
Position: 1004-1012
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S21
Chemical type: Peptide from protein
Sequence: LQTYVTQQL
Position: 1004-1012
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S22
Chemical type: Peptide from protein
Sequence: QSAPHGVVF
Position: 1054-1062
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S22
Chemical type: Peptide from protein
Sequence: QSAPHGVVF
Position: 1054-1062
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S23
Chemical type: Peptide from protein
Sequence: SAPHGVVFL
Position: 1055-1063
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S23
Chemical type: Peptide from protein
Sequence: SAPHGVVFL
Position: 1055-1063
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S24
Chemical type: Peptide from protein
Sequence: VYDPLQPEL
Position: 1137-1145
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S24
Chemical type: Peptide from protein
Sequence: VYDPLQPEL
Position: 1137-1145
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Negative

Epitope: S25
Chemical type: Peptide from protein
Sequence: RLNEVAKNL
Position: 1185-1193
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S25
Chemical type: Peptide from protein
Sequence: RLNEVAKNL
Position: 1185-1193
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S25
Chemical type: Peptide from protein
Sequence: RLNEVAKNL
Position: 1185-1193
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive

Epitope: S25
Chemical type: Peptide from protein
Sequence: RLNEVAKNL
Position: 1185-1193
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive

Epitope: N1
Chemical type: Peptide from protein
Sequence: LQLPQGTTL
Position: 159-167
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Negative

Epitope: N1
Chemical type: Peptide from protein
Sequence: LQLPQGTTL
Position: 159-167
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Negative

Epitope: N3
Chemical type: Peptide from protein
Sequence: FAPSASAFF
Position: 307-315
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Negative

Epitope: N3
Chemical type: Peptide from protein
Sequence: FAPSASAFF
Position: 307-315
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Negative

Epitope: N4
Chemical type: Peptide from protein
Sequence: KLDDKDPNF
Position: 338-346
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Negative

Epitope: N4
Chemical type: Peptide from protein
Sequence: KLDDKDPNF
Position: 338-346
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Negative

Epitope: M1
Chemical type: Peptide from protein
Sequence: RLFARTRSM
Position: 101-109
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Negative

Epitope: M1
Chemical type: Peptide from protein
Sequence: RLFARTRSM
Position: 101-109
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Negative

Epitope: M2
Chemical type: Peptide from protein
Sequence: SFNPETNIL
Position: 111-119
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Negative

Epitope: M2
Chemical type: Peptide from protein
Sequence: SFNPETNIL
Position: 111-119
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Negative

Epitope: M4
Chemical type: Peptide from protein
Sequence: NVPLHGTIL
Position: 121-129
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Negative

Epitope: M4
Chemical type: Peptide from protein
Sequence: NVPLHGTIL
Position: 121-129
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Negative

Epitope: M5
Chemical type: Peptide from protein
Sequence: SSSDNIALL
Position: 212-220
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Negative

Epitope: M5
Chemical type: Peptide from protein
Sequence: SSSDNIALL
Position: 212-220
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Negative

Epitope: M6
Chemical type: Peptide from protein
Sequence: SSDNIALLV
Position: 213-221
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Negative

Epitope: M6
Chemical type: Peptide from protein
Sequence: SSDNIALLV
Position: 213-221
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Negative

Epitope: E1
Chemical type: Peptide from protein
Sequence: YVYSRVKNL
Position: 57-65
Source molecule (GenBank): P0DTC4.1
Assay category: MhcBinding
Result: Negative

Epitope: E1
Chemical type: Peptide from protein
Sequence: YVYSRVKNL
Position: 57-65
Source molecule (GenBank): P0DTC4.1
Assay category: MhcBinding
Result: Negative