Reference: W A Hayman; E R Brandt; W A Relf; J Cooper; A Saul; M F Good. "Mapping the minimal murine T cell and B cell epitopes within a peptide vaccine candidate from the conserved region of the M protein of group A streptococcus." International immunology (1997).

Epitope: M protein T cell epitope
Chemical type: Peptide from protein
Sequence: RDLDASREAKKQ
Position: 356-367
Source molecule (GenBank): CAA50980.1
Assay category: TCell
Result: Positive
Host: M 5-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M protein B cell epitope
Chemical type: Peptide from protein
Sequence: ASREAKKQVEKALE
Position: 327-340
Source molecule (GenBank): AAP32473.1
Assay category: BCell
Result: Positive
Host: M 5-6 weeks

Epitope: M protein B cell epitope
Chemical type: Peptide from protein
Sequence: ASREAKKQVEKALE
Position: 327-340
Source molecule (GenBank): AAP32473.1
Assay category: BCell
Result: Positive

Epitope: M protein peptide 145
Chemical type: Peptide from protein
Sequence: LRRDLDASREAKKQVEKALE
Position: 426-445
Source molecule (GenBank): CAA56449.1
Assay category: BCell
Result: Positive
Host: M 5-6 weeks

Epitope: M protein peptide J1
Chemical type: Peptide, no natural source
Sequence: QLEDKVKQLRRDLDASREAKEELQDKVK
Assay category: BCell
Result: Negative
Host: M 5-6 weeks

Epitope: M protein peptide J1
Chemical type: Peptide, no natural source
Sequence: QLEDKVKQLRRDLDASREAKEELQDKVK
Assay category: BCell
Result: Positive

Epitope: M protein peptide J1
Chemical type: Peptide, no natural source
Sequence: QLEDKVKQLRRDLDASREAKEELQDKVK
Assay category: TCell
Result: Negative
Host: M 5-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M protein peptide J2
Chemical type: Peptide, no natural source
Sequence: LEDKVKQARRDLDASREAKKELQDKVKQ
Assay category: BCell
Result: Positive
Host: M 5-6 weeks

Epitope: M protein peptide J2
Chemical type: Peptide, no natural source
Sequence: LEDKVKQARRDLDASREAKKELQDKVKQ
Assay category: BCell
Result: Positive

Epitope: M protein peptide J2
Chemical type: Peptide, no natural source
Sequence: LEDKVKQARRDLDASREAKKELQDKVKQ
Assay category: TCell
Result: Negative
Host: M 5-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M protein peptide J7
Chemical type: Peptide, no natural source
Sequence: KQAEDKVKASREAKKQVEKAVKQLEDKV
Assay category: BCell
Result: Positive

Epitope: M protein peptide J7
Chemical type: Peptide, no natural source
Sequence: KQAEDKVKASREAKKQVEKAVKQLEDKV
Assay category: BCell
Result: Positive
Host: M 5-6 weeks

Epitope: M protein peptide J7
Chemical type: Peptide, no natural source
Sequence: KQAEDKVKASREAKKQVEKAVKQLEDKV
Assay category: TCell
Result: Negative
Host: M 5-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M protein peptide J9
Chemical type: Peptide, no natural source
Sequence: AEDKVKQLREAKKQVEKALEQLEDKVQL
Assay category: BCell
Result: Positive

Epitope: M protein peptide J9
Chemical type: Peptide, no natural source
Sequence: AEDKVKQLREAKKQVEKALEQLEDKVQL
Assay category: BCell
Result: Positive
Host: M 5-6 weeks

Epitope: M protein peptide J9
Chemical type: Peptide, no natural source
Sequence: AEDKVKQLREAKKQVEKALEQLEDKVQL
Assay category: TCell
Result: Negative
Host: M 5-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M protein peptide J3
Chemical type: Peptide, no natural source
Sequence: EDKVKQAERDLDASREAKKQLQDKVKQL
Assay category: BCell
Result: Negative
Host: M 5-6 weeks

Epitope: M protein peptide J3
Chemical type: Peptide, no natural source
Sequence: EDKVKQAERDLDASREAKKQLQDKVKQL
Assay category: BCell
Result: Positive
Host: M 5-6 weeks

Epitope: M protein peptide J3
Chemical type: Peptide, no natural source
Sequence: EDKVKQAERDLDASREAKKQLQDKVKQL
Assay category: TCell
Result: Positive
Host: M 5-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M protein peptide J4
Chemical type: Peptide, no natural source
Sequence: DKVKQAEDDLDASREAKKQVQDKVKQLE
Assay category: BCell
Result: Negative
Host: M 5-6 weeks

Epitope: M protein peptide J4
Chemical type: Peptide, no natural source
Sequence: DKVKQAEDDLDASREAKKQVQDKVKQLE
Assay category: BCell
Result: Negative
Host: M 5-6 weeks

Epitope: M protein peptide J4
Chemical type: Peptide, no natural source
Sequence: DKVKQAEDDLDASREAKKQVQDKVKQLE
Assay category: TCell
Result: Negative
Host: M 5-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M protein peptide J5
Chemical type: Peptide, no natural source
Sequence: KVKQAEDKLDASREAKKQVEDKVKQLED
Assay category: BCell
Result: Positive
Host: M 5-6 weeks

Epitope: M protein peptide J5
Chemical type: Peptide, no natural source
Sequence: KVKQAEDKLDASREAKKQVEDKVKQLED
Assay category: BCell
Result: Negative
Host: M 5-6 weeks

Epitope: M protein peptide J5
Chemical type: Peptide, no natural source
Sequence: KVKQAEDKLDASREAKKQVEDKVKQLED
Assay category: TCell
Result: Negative
Host: M 5-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M protein peptide J6
Chemical type: Peptide, no natural source
Sequence: VKQAEDKVDASREAKKQVEKKVKQLEDK
Assay category: BCell
Result: Negative
Host: M 5-6 weeks

Epitope: M protein peptide J6
Chemical type: Peptide, no natural source
Sequence: VKQAEDKVDASREAKKQVEKKVKQLEDK
Assay category: BCell
Result: Negative
Host: M 5-6 weeks

Epitope: M protein peptide J6
Chemical type: Peptide, no natural source
Sequence: VKQAEDKVDASREAKKQVEKKVKQLEDK
Assay category: TCell
Result: Negative
Host: M 5-6 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M protein peptide 160
Chemical type: Peptide from protein
Sequence: AVTRGTINDPQRAKEALDYE
Assay category: BCell
Result: Positive
Host: M 5-6 weeks

Epitope: J14
Chemical type: Peptide, no natural source
Sequence: KQAEDKVKASREAKKQVEKALEQLEDKVK
Assay category: BCell
Result: Positive
Host: M 5-6 weeks

Epitope: J14
Chemical type: Peptide, no natural source
Sequence: KQAEDKVKASREAKKQVEKALEQLEDKVK
Assay category: BCell
Result: Positive
Host: M 5-6 weeks