Reference: Xilin Wu; Yaxing Wang; Lin Cheng; Fengfeng Ni; Linjing Zhu; Sen Ma; Bilian Huang; Mengmeng Ji; Huimin Hu; Yuncheng Li; Shijie Xu; Haixia Shi; Doudou Zhang; Linshuo Liu; Waqas Nawaz; Qinxue Hu; Sheng Ye; Yalan Liu; Zhiwei Wu. "Short-Term Instantaneous Prophylaxis and Efficient Treatment Against SARS-CoV-2 in hACE2 Mice Conferred by an Intranasal Nanobody (Nb22)." Frontiers in immunology (2022).

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00174
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.312
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 22100000
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.67
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, G447, N448, Y449, N450, L452, Y453, F456, E484, G485, C488, Y489, F490, Q493, S494, Y495
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.92
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00174
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.312
Host: F 2-3 years

Epitope: Epitope of nanobody Nb22 on SARS-CoV-2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K442, G444, Y447, N448, R450, L453, F454, E482, G483, F484, C486, Y487, F488, L490, Q491, S492, G494
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Quantitative measurement: 22100000
Host: F 2-3 years