Reference: Yuki Yajima; Akemi Kosaka; Takayuki Ohkuri; Yoshihiko Hirohashi; Dongliang Li; Takeshi Nagasaki; Toshihiro Nagato; Toshihiko Torigoe; Hiroya Kobayashi. "SARS-CoV-2 spike protein-derived immunogenic peptides that are promiscuously presented by several HLA-class II molecules and their potential for inducing acquired immunity." Heliyon (2023).

Epitope: Spike(451-461)
Chemical type: Peptide from protein
Sequence: YLYRLFRKSNL
Position: 451-461
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(451-461)
Chemical type: Peptide from protein
Sequence: YLYRLFRKSNL
Position: 451-461
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(451-461)
Chemical type: Peptide from protein
Sequence: YLYRLFRKSNL
Position: 451-461
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(451-461)
Chemical type: Peptide from protein
Sequence: YLYRLFRKSNL
Position: 451-461
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(451-461)
Chemical type: Peptide from protein
Sequence: YLYRLFRKSNL
Position: 451-461
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(461-470)
Chemical type: Peptide from protein
Sequence: LKPFERDIST
Position: 461-470
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(461-470)
Chemical type: Peptide from protein
Sequence: LKPFERDIST
Position: 461-470
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(461-470)
Chemical type: Peptide from protein
Sequence: LKPFERDIST
Position: 461-470
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(461-470)
Chemical type: Peptide from protein
Sequence: LKPFERDIST
Position: 461-470
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(461-470)
Chemical type: Peptide from protein
Sequence: LKPFERDIST
Position: 461-470
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(461-470)
Chemical type: Peptide from protein
Sequence: LKPFERDIST
Position: 461-470
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(461-470)
Chemical type: Peptide from protein
Sequence: LKPFERDIST
Position: 461-470
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(454-461)
Chemical type: Peptide from protein
Sequence: RLFRKSNL
Position: 454-461
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(454-461)
Chemical type: Peptide from protein
Sequence: RLFRKSNL
Position: 454-461
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(454-461)
Chemical type: Peptide from protein
Sequence: RLFRKSNL
Position: 454-461
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(454-461)
Chemical type: Peptide from protein
Sequence: RLFRKSNL
Position: 454-461
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(454-461)
Chemical type: Peptide from protein
Sequence: RLFRKSNL
Position: 454-461
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(454-461)
Chemical type: Peptide from protein
Sequence: RLFRKSNL
Position: 454-461
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(454-461)
Chemical type: Peptide from protein
Sequence: RLFRKSNL
Position: 454-461
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(454-461)
Chemical type: Peptide from protein
Sequence: RLFRKSNL
Position: 454-461
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Spike(454-461)
Chemical type: Peptide from protein
Sequence: RLFRKSNL
Position: 454-461
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: E4 Spike489-513(N501Y)
Chemical type: Peptide from protein
Sequence: YFPLQSYGFQPTYGVGYQPYRVVVL
Position: 486-510
Source molecule (GenBank): QSJ05725.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E4 Spike489-513(N501Y)
Chemical type: Peptide from protein
Sequence: YFPLQSYGFQPTYGVGYQPYRVVVL
Position: 486-510
Source molecule (GenBank): QSJ05725.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: E4 Spike489-513(N501Y)
Chemical type: Peptide from protein
Sequence: YFPLQSYGFQPTYGVGYQPYRVVVL
Position: 486-510
Source molecule (GenBank): QSJ05725.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: E5 Spike(448-477)
Chemical type: Peptide from protein
Sequence: NYNYLYRLFRKSNLKPFERDISTEIYQAGS
Position: 448-477
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E6 Spike489-513(WT, N501N)
Chemical type: Peptide from protein
Sequence: YFPLQSYGFQPTNGVGYQPYRVVVL
Position: 489-513
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E7 Spike489-513(F490S)
Chemical type: Peptide from protein
Sequence: YSPLQSYGFQPTNGVGYQPYRVVVL
Position: 482-506
Source molecule (GenBank): QTJ90974.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E8 Spike(448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated