Reference: Marie-Anne Petit; Colette Jolivet-Reynaud; Estelle Peronnet; Yvonne Michal; Christian Trépo. "Mapping of a conformational epitope shared between E1 and E2 on the serum-derived human hepatitis C virus envelope." The Journal of biological chemistry (2003).

Epitope: HCV E1E2 (D32.10)
Chemical type: Discontinuous protein residues
Discontinuous residues: R297, H298, W299, T300, T301, Q302, G303, C304, N305, C306, P480, D481, Q482, R483, P484, Y485, C486, W487, H488, Y489, P490, P491, K492, P493, C494, Y613, R614, L615, W616, H617, Y618, P619, C620, T621
Source molecule (GenBank): P26664.3
Assay category: BCell
Result: Positive

Epitope: HCV E1E2 (D32.10)
Chemical type: Discontinuous protein residues
Discontinuous residues: R297, H298, W299, T300, T301, Q302, G303, C304, N305, C306, P480, D481, Q482, R483, P484, Y485, C486, W487, H488, Y489, P490, P491, K492, P493, C494, Y613, R614, L615, W616, H617, Y618, P619, C620, T621
Source molecule (GenBank): P26664.3
Assay category: BCell
Result: Positive

Epitope: HCV E1E2 (D32.10)
Chemical type: Discontinuous protein residues
Discontinuous residues: R297, H298, W299, T300, T301, Q302, G303, C304, N305, C306, P480, D481, Q482, R483, P484, Y485, C486, W487, H488, Y489, P490, P491, K492, P493, C494, Y613, R614, L615, W616, H617, Y618, P619, C620, T621
Source molecule (GenBank): P26664.3
Assay category: BCell
Result: Positive

Epitope: clone 1
Chemical type: Peptide, no natural source
Sequence: SPLRRHYELPLIQ
Assay category: BCell
Result: Positive

Epitope: clone 2
Chemical type: Peptide, no natural source
Sequence: WPHNHSTHSRTH
Assay category: BCell
Result: Positive

Epitope: clone 3
Chemical type: Peptide, no natural source
Sequence: FPKYHPRFHKHA
Assay category: BCell
Result: Positive

Epitope: clone 4
Chemical type: Peptide, no natural source
Sequence: SQRSRHWHDVPK
Assay category: BCell
Result: Positive

Epitope: clone 6
Chemical type: Peptide, no natural source
Sequence: WKMPRATDWNLR
Assay category: BCell
Result: Positive

Epitope: clone 7
Chemical type: Peptide, no natural source
Sequence: HWGNHSKSHPQR
Assay category: BCell
Result: Positive

Epitope: clone 8
Chemical type: Peptide, no natural source
Sequence: WHRTPSTLWGVI
Assay category: BCell
Result: Positive

Epitope: clone 9
Chemical type: Peptide, no natural source
Sequence: WHKLPGHPRTV
Assay category: BCell
Result: Positive

Epitope: clone 10
Chemical type: Peptide, no natural source
Sequence: TFAWHKPRVNLG
Assay category: BCell
Result: Positive

Epitope: clone 12
Chemical type: Peptide, no natural source
Sequence: HSSWYIQHFPPL
Assay category: BCell
Result: Positive

Epitope: clone 13
Chemical type: Peptide, no natural source
Sequence: FPAHPLPRLPSL
Assay category: BCell
Result: Positive

Epitope: clone 14
Chemical type: Peptide, no natural source
Sequence: WHWNKPIRPPLR
Assay category: BCell
Result: Positive

Epitope: clone 15
Chemical type: Peptide, no natural source
Sequence: QPYKLQAAATLY
Assay category: BCell
Result: Positive

Epitope: clone 16
Chemical type: Peptide, no natural source
Sequence: HLYHKNRNHIAY
Assay category: BCell
Result: Positive

Epitope: clone 17
Chemical type: Peptide, no natural source
Sequence: WSPGQQRLHNST
Assay category: BCell
Result: Positive

Epitope: E1-(292-306)
Chemical type: Peptide from protein
Sequence: TFSPRRHWTTQGCNC
Position: 176-190
Source molecule (GenBank): ABB77003.1
Assay category: BCell
Result: Positive

Epitope: E2-(608-622)
Chemical type: Peptide from protein
Sequence: LVDYPYRLWHYPCTI
Position: 608-622
Source molecule (GenBank): ANN11860.1
Assay category: BCell
Result: Positive

Epitope: E2-(480-494)
Chemical type: Peptide from protein
Sequence: PDQRPYCWHYPPKPC
Position: 480-494
Source molecule (GenBank): BAA00705.1
Assay category: BCell
Result: Positive