Reference: Ashutosh Mangalam; Moses Rodriguez; Chella David. "Role of MHC class II expressing CD4+ T cells in proteolipid protein(91-110)-induced EAE in HLA-DR3 transgenic mice." European journal of immunology (2006).

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>91-110</sub>
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>41-60</sub>
Chemical type: Peptide from protein
Sequence: GTEKLIETYFSKNYQDYEYL
Position: 42-61
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>101-120</sub>
Chemical type: Peptide from protein
Sequence: GDYKTTICGKGLSATVTGGQ
Position: 102-121
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>111-130</sub>
Chemical type: Peptide from protein
Sequence: GLSATVTGGQKGRGSRGQHQ
Position: 112-131
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>139-154</sub>
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKFVGI
Position: 140-155
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>179-198</sub>
Chemical type: Peptide from protein
Sequence: TWTTCQSIAFPSKTSASIGS
Position: 180-199
Source molecule (GenBank): AAA60117.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>208-227</sub>
Chemical type: Peptide from protein
Sequence: VLPWNAFPGKVCGSNLLSIC
Position: 209-228
Source molecule (GenBank): AAA60117.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo