Reference: Chao Zhang; Cong Xu; Wenlong Dai; Yifan Wang; Zhi Liu; Xueyang Zhang; Xuesong Wang; Haikun Wang; Sitang Gong; Yao Cong; Zhong Huang. "Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections." Nature communications (2021).

Epitope: Epitope of 8F12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R649, E768, N770, G771, L772, A827; B: A203, H204, N205, T206, T208, S209, G211, D213, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of 8F12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R649, E768, N770, G771, L772, A827; B: A203, H204, N205, T206, T208, S209, G211, D213, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of 8F12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R649, E768, N770, G771, L772, A827; B: A203, H204, N205, T206, T208, S209, G211, D213, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive-Low
Host: F 6-8 weeks

Epitope: Epitope of 8F12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R649, E768, N770, G771, L772, A827; B: A203, H204, N205, T206, T208, S209, G211, D213, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of 8F12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R649, E768, N770, G771, L772, A827; B: A203, H204, N205, T206, T208, S209, G211, D213, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of 8F12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R649, E768, N770, G771, L772, A827; B: A203, H204, N205, T206, T208, S209, G211, D213, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.92
Host: F 6-8 weeks

Epitope: Epitope of 8F12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R649, E768, N770, G771, L772, A827; B: A203, H204, N205, T206, T208, S209, G211, D213, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Quantitative measurement: 380000.0
Host: F 6-8 weeks

Epitope: Epitope of 8F12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R649, E768, N770, G771, L772, A827; B: A203, H204, N205, T206, T208, S209, G211, D213, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00035
Host: F 6-8 weeks

Epitope: Epitope of 8F12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R649, E768, N770, G771, L772, A827; B: A203, H204, N205, T206, T208, S209, G211, D213, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of 8F12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R649, E768, N770, G771, L772, A827; B: A203, H204, N205, T206, T208, S209, G211, D213, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive-Low
Host: F 6-8 weeks

Epitope: Epitope of 8F12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R649, E768, N770, G771, L772, A827; B: A203, H204, N205, T206, T208, S209, G211, D213, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of 2H12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K769, N770, G771, L772, N776, M824; B: H204, N205, T206, N207, T208, S209, G211, D213, D214, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of 2H12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K769, N770, G771, L772, N776, M824; B: H204, N205, T206, N207, T208, S209, G211, D213, D214, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of 2H12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K769, N770, G771, L772, N776, M824; B: H204, N205, T206, N207, T208, S209, G211, D213, D214, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of 2H12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K769, N770, G771, L772, N776, M824; B: H204, N205, T206, N207, T208, S209, G211, D213, D214, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of 2H12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K769, N770, G771, L772, N776, M824; B: H204, N205, T206, N207, T208, S209, G211, D213, D214, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of 2H12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K769, N770, G771, L772, N776, M824; B: H204, N205, T206, N207, T208, S209, G211, D213, D214, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Quantitative measurement: 230000.0
Host: F 6-8 weeks

Epitope: Epitope of 2H12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K769, N770, G771, L772, N776, M824; B: H204, N205, T206, N207, T208, S209, G211, D213, D214, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of 2H12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K769, N770, G771, L772, N776, M824; B: H204, N205, T206, N207, T208, S209, G211, D213, D214, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of 2H12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K769, N770, G771, L772, N776, M824; B: H204, N205, T206, N207, T208, S209, G211, D213, D214, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of 2H12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K769, N770, G771, L772, N776, M824; B: H204, N205, T206, N207, T208, S209, G211, D213, D214, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Quantitative measurement: 9.6
Host: F 6-8 weeks

Epitope: Epitope of 2H12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K769, N770, G771, L772, N776, M824; B: H204, N205, T206, N207, T208, S209, G211, D213, D214, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0022
Host: F 6-8 weeks

Epitope: Epitope of 2H12 Fab on EV-D68
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K769, N770, G771, L772, N776, M824; B: H204, N205, T206, N207, T208, S209, G211, D213, D214, N225, H226
Source molecule (GenBank): AIS73051.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks