Reference: H Sugawa; T Akamizu; S Kosugi; Y Ueda; C Ohta; J Okuda; T Mori. "Presence of heterogeneous thyroid-stimulating antibodies in sera from individual Graves' patients as shown by synthesized thyrotropin receptor peptide application: evidence showing two independent epitopes and a possible recognition of two epitopic regions by one antibody molecule." European journal of endocrinology / European Federation of Endocrine Societies (1995).

Epitope: human TSH-R P58-19
Chemical type: Peptide from protein
Sequence: KLIETHLRTIPSHAFSNLP
Position: 58-76
Source molecule (GenBank): AAI27629.1
Assay category: BCell
Result: Negative

Epitope: human TSH-R P91-29
Chemical type: Peptide from protein
Sequence: QLESHSFYNLSKVTHIEIRNTRNLTYIDP
Position: 91-119
Source molecule (GenBank): AAI27629.1
Assay category: BCell
Result: Positive

Epitope: human TSH-R P91-29
Chemical type: Peptide from protein
Sequence: QLESHSFYNLSKVTHIEIRNTRNLTYIDP
Position: 91-119
Source molecule (GenBank): AAI27629.1
Assay category: BCell
Result: Positive

Epitope: human TSH-R P115-20
Chemical type: Peptide from protein
Sequence: TYIDPDALKELPLLKFLGIF
Position: 115-134
Source molecule (GenBank): AAI27629.1
Assay category: BCell
Result: Negative

Epitope: human TSH-R P135-20
Chemical type: Peptide from protein
Sequence: NTGLKMFPDLTKVYSTDIFFILEIT
Position: 135-159
Source molecule (GenBank): AAI27629.1
Assay category: BCell
Result: Negative

Epitope: human TSH-R P172-18
Chemical type: Peptide from protein
Sequence: FQGLCNETLTLKLYNNGF
Position: 172-189
Source molecule (GenBank): AAI27629.1
Assay category: BCell
Result: Negative

Epitope: human TSH-R P190-24
Chemical type: Peptide from protein
Sequence: TSVQGYAFNGTKLDAVYLNKNKYL
Position: 190-213
Source molecule (GenBank): AAI27629.1
Assay category: BCell
Result: Negative

Epitope: human TSH-R P217-24
Chemical type: Peptide from protein
Sequence: DKDAFGGVYSGPSLLDVSQTSVTA
Position: 217-240
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Negative

Epitope: human TSH-R P241-20
Chemical type: Peptide from protein
Sequence: LPSKGLEHLKELIARNTWTL
Position: 241-260
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive

Epitope: human TSH-R P261-20
Chemical type: Peptide from protein
Sequence: KKLPLSLSFLHLTRADLSYP
Position: 261-280
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Negative

Epitope: human TSH-R P281-19
Chemical type: Peptide from protein
Sequence: SHCCAFKNQKKIRGILESL
Position: 281-299
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive

Epitope: human TSH-R P287-18
Chemical type: Peptide from protein
Sequence: KNQKKIRGILESLMCNES
Position: 287-304
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Negative

Epitope: human TSH-R P287-18
Chemical type: Peptide from protein
Sequence: KNQKKIRGILESLMCNES
Position: 287-304
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive

Epitope: human TSH-R P324-20
Chemical type: Peptide from protein
Sequence: QEYEENLGDSIVGYKEKSKF
Position: 324-343
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive

Epitope: human TSH-R P338-16
Chemical type: Peptide from protein
Sequence: KEKSKFQDTHNNAHYY
Position: 338-353
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Negative

Epitope: human TSH-R P354-14
Chemical type: Peptide from protein
Sequence: VFFEEQEDEIIGFG
Position: 354-367
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive-High

Epitope: human TSH-R P354-14
Chemical type: Peptide from protein
Sequence: VFFEEQEDEIIGFG
Position: 354-367
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive

Epitope: human TSH-R P361-20
Chemical type: Peptide from protein
Sequence: DEIIGFGQELKNPQEETLQAFD
Position: 361-382
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive

Epitope: human TSH-R P385-13
Chemical type: Peptide from protein
Sequence: YDYTICGDSEDMV
Position: 385-397
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Positive

Epitope: human TSH-R P391-21
Chemical type: Peptide from protein
Sequence: CGDSEDMVCTPKSDEFNPCEDI
Position: 390-411
Source molecule (GenBank): AAR07906.1
Assay category: BCell
Result: Negative