Reference: Annemieke M H Boots; Henk Hubers; Milou Kouwijzer; Leontien den Hoed-van Zandbrink; Bernice M Westrek-Esselink; Cindy van Doorn; Rachel Stenger; Ebo S Bos; Marie-jose C van Lierop; Gijs F Verheijden; Cornelis M Timmers; Catharina J van Staveren. "Identification of an altered peptide ligand based on the endogenously presented, rheumatoid arthritis-associated, human cartilage glycoprotein-39(263-275) epitope: an MHC anchor variant peptide for immune modulation." Arthritis research & therapy (2007).

Epitope: HC gp-39 (263-275)
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: HC gp-39 (263-275)
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: HC gp-39 (263-275)
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 (263-275)
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 (263-275)
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 (263-275)
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 (263-275)
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 (263-275)
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 (263-275)
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 (263-275)
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 (263-275)
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 (263-275)
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 (263-275)
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 (263-275)
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 (263-275)
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 120.0

Epitope: HC gp-39 (263-274)
Chemical type: Peptide from protein
Sequence: RSFTLASSETGV
Position: 263-274
Source molecule (GenBank): P36222.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 90.0

Epitope: HC gp-39 (263-273)
Chemical type: Peptide from protein
Sequence: RSFTLASSETG
Position: 263-273
Source molecule (GenBank): P36222.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 200.0

Epitope: HC gp-39 (263-272)
Chemical type: Peptide from protein
Sequence: RSFTLASSET
Position: 263-272
Source molecule (GenBank): P36222.2
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 7000.0

Epitope: HC gp-39 (264-275)
Chemical type: Peptide from protein
Sequence: SFTLASSETGVG
Position: 264-275
Source molecule (GenBank): P36222.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 90.0

Epitope: HC gp-39 (265-275)
Chemical type: Peptide from protein
Sequence: FTLASSETGVG
Position: 265-275
Source molecule (GenBank): P36222.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 110.0

Epitope: HC gp-39 (266-275)
Chemical type: Peptide from protein
Sequence: TLASSETGVG
Position: 266-275
Source molecule (GenBank): P36222.2
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: HC gp-39 (267-275)
Chemical type: Peptide from protein
Sequence: LASSETGVG
Position: 267-275
Source molecule (GenBank): P36222.2
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: HC gp-39 (264-274)
Chemical type: Peptide from protein
Sequence: SFTLASSETGV
Position: 264-274
Source molecule (GenBank): P36222.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 120.0

Epitope: HC gp-39 R263A1
Chemical type: Peptide, no natural source
Sequence: ASFTLASSETGVG
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 100.0

Epitope: HC gp-39 F265A3
Chemical type: Peptide, no natural source
Sequence: RSATLASSETGVG
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 35000.0

Epitope: HC gp-39 T266A4
Chemical type: Peptide, no natural source
Sequence: RSFALASSETGVG
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 60.0

Epitope: HC gp-39 A268D6
Chemical type: Peptide, no natural source
Sequence: RSFTLDSSETGVG
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 240.0

Epitope: HC gp-39 S269A7
Chemical type: Peptide, no natural source
Sequence: RSFTLAASETGVG
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 50.0

Epitope: HC gp-39 S270A8
Chemical type: Peptide, no natural source
Sequence: RSFTLASAETGVG
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 50.0

Epitope: HC gp-39 E271A9
Chemical type: Peptide, no natural source
Sequence: RSFTLASSATGVG
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 40.0

Epitope: HC gp-39 T272A10
Chemical type: Peptide, no natural source
Sequence: RSFTLASSEAGVG
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 40.0

Epitope: HC gp-39 G273A11
Chemical type: Peptide, no natural source
Sequence: RSFTLASSETAVG
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 50.0

Epitope: HC gp-39 V274A12
Chemical type: Peptide, no natural source
Sequence: RSFTLASSETGAG
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 60.0

Epitope: HC gp-39 G275A13
Chemical type: Peptide, no natural source
Sequence: RSFTLASSETGVA
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 50.0

Epitope: HC gp-39 A3/A8
Chemical type: Peptide, no natural source
Sequence: RSATLASAETGVG
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 36000.0

Epitope: HC gp-39 Dip, SerBzl, or Cha
Chemical type: Peptide, no natural source
Sequence: RSFTLASSETGVG
Assay category: TCell
Result: Positive-Low
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 Dip, SerBzl, or Cha
Chemical type: Peptide, no natural source
Sequence: RSFTLASSETGVG
Assay category: TCell
Result: Positive-Low
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 Dip, SerBzl, or Cha
Chemical type: Peptide, no natural source
Sequence: RSFTLASSETGVG
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 Dip, SerBzl, or Cha
Chemical type: Peptide, no natural source
Sequence: RSFTLASSETGVG
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 Dip, SerBzl, or Cha
Chemical type: Peptide, no natural source
Sequence: RSFTLASSETGVG
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 Dip, SerBzl, or Cha
Chemical type: Peptide, no natural source
Sequence: RSFTLASSETGVG
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 Dip, SerBzl, or Cha
Chemical type: Peptide, no natural source
Sequence: RSFTLASSETGVG
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: HC gp-39 Dip, SerBzl, or Cha
Chemical type: Peptide, no natural source
Sequence: RSFTLASSETGVG
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 7.0