Reference: Soheila Gharagozlou; Ramazan A Sharifian; Jalal Khoshnoodi; Katayoon Karimi; Monica Milani; David K Okita; Fazel Shokri; Bianca M Conti-Fine. "Epitope specificity of anti-factor VIII antibodies from inhibitor positive acquired and congenital haemophilia A patients using synthetic peptides spanning A and C domains." Thrombosis and haemostasis (2009).

Epitope: FVIII (371-390)
Chemical type: Peptide from protein
Sequence: IRSVAKKHPKTWVHYIAAEE
Position: 390-409
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (371-390)
Chemical type: Peptide from protein
Sequence: IRSVAKKHPKTWVHYIAAEE
Position: 390-409
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (391-410)
Chemical type: Peptide from protein
Sequence: EDWDYAPLVLAPDDRSYKSQ
Position: 410-429
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (391-410)
Chemical type: Peptide from protein
Sequence: EDWDYAPLVLAPDDRSYKSQ
Position: 410-429
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (401-420)
Chemical type: Peptide from protein
Sequence: APDDRSYKSQYLNNGPQRIG
Position: 420-439
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (401-420)
Chemical type: Peptide from protein
Sequence: APDDRSYKSQYLNNGPQRIG
Position: 420-439
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (421-440)
Chemical type: Peptide from protein
Sequence: RKYKKVRFMAYTDETFKTRE
Position: 440-459
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (421-440)
Chemical type: Peptide from protein
Sequence: RKYKKVRFMAYTDETFKTRE
Position: 440-459
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative

Epitope: FVIII (431-450)
Chemical type: Peptide from protein
Sequence: YTDETFKTREAIQHESGILG
Position: 450-469
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (431-450)
Chemical type: Peptide from protein
Sequence: YTDETFKTREAIQHESGILG
Position: 450-469
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (441-460)
Chemical type: Peptide from protein
Sequence: AIQHESGILGPLLYGEVGDT
Position: 460-479
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (441-460)
Chemical type: Peptide from protein
Sequence: AIQHESGILGPLLYGEVGDT
Position: 460-479
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (451-470)
Chemical type: Peptide from protein
Sequence: PLLYGEVGDTLLIIFKNQAS
Position: 470-489
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (451-470)
Chemical type: Peptide from protein
Sequence: PLLYGEVGDTLLIIFKNQAS
Position: 470-489
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (471-490)
Chemical type: Peptide from protein
Sequence: RPYNIYPHGITDVRPLYSRR
Position: 490-509
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (471-490)
Chemical type: Peptide from protein
Sequence: RPYNIYPHGITDVRPLYSRR
Position: 490-509
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (481-500)
Chemical type: Peptide from protein
Sequence: TDVRPLYSRRLPKGVKHLKD
Position: 500-519
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (481-500)
Chemical type: Peptide from protein
Sequence: TDVRPLYSRRLPKGVKHLKD
Position: 500-519
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (491-510)
Chemical type: Peptide from protein
Sequence: LPKGVKHLKDFPILPGEIFK
Position: 510-529
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (491-510)
Chemical type: Peptide from protein
Sequence: LPKGVKHLKDFPILPGEIFK
Position: 510-529
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (501-520)
Chemical type: Peptide from protein
Sequence: FPILPGEIFKYKWTVTVEDG
Position: 520-539
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (501-520)
Chemical type: Peptide from protein
Sequence: FPILPGEIFKYKWTVTVEDG
Position: 520-539
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (511-530)
Chemical type: Peptide from protein
Sequence: YKWTVTVEDGPTKSDPRCLT
Position: 530-549
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (511-530)
Chemical type: Peptide from protein
Sequence: YKWTVTVEDGPTKSDPRCLT
Position: 530-549
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (521-540)
Chemical type: Peptide from protein
Sequence: PTKSDPRCLTRYYSSFVNME
Position: 540-559
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (521-540)
Chemical type: Peptide from protein
Sequence: PTKSDPRCLTRYYSSFVNME
Position: 540-559
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (541-560)
Chemical type: Peptide from protein
Sequence: RDLASGLIGPLLICYKESVD
Position: 560-579
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (541-560)
Chemical type: Peptide from protein
Sequence: RDLASGLIGPLLICYKESVD
Position: 560-579
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (551-570)
Chemical type: Peptide from protein
Sequence: LLICYKESVDQRGNQIMSDK
Position: 570-589
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (551-570)
Chemical type: Peptide from protein
Sequence: LLICYKESVDQRGNQIMSDK
Position: 570-589
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative

Epitope: FVIII (561-580)
Chemical type: Peptide from protein
Sequence: QRGNQIMSDKRNVILFSVFD
Position: 580-599
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (561-580)
Chemical type: Peptide from protein
Sequence: QRGNQIMSDKRNVILFSVFD
Position: 580-599
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (571-590)
Chemical type: Peptide from protein
Sequence: RNVILFSVFDENRSWYLTEN
Position: 590-609
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (571-590)
Chemical type: Peptide from protein
Sequence: RNVILFSVFDENRSWYLTEN
Position: 590-609
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (581-600)
Chemical type: Peptide from protein
Sequence: ENRSWYLTENIQRFLPNPAG
Position: 600-619
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (581-600)
Chemical type: Peptide from protein
Sequence: ENRSWYLTENIQRFLPNPAG
Position: 600-619
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (591-610)
Chemical type: Peptide from protein
Sequence: IQRFLPNPAGVQLEDPEFQA
Position: 610-629
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (591-610)
Chemical type: Peptide from protein
Sequence: IQRFLPNPAGVQLEDPEFQA
Position: 610-629
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (601-620)
Chemical type: Peptide from protein
Sequence: VQLEDPEFQASNIMHSINGY
Position: 620-639
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (601-620)
Chemical type: Peptide from protein
Sequence: VQLEDPEFQASNIMHSINGY
Position: 620-639
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (611-630)
Chemical type: Peptide from protein
Sequence: SNIMHSINGYVFDSLQLSVC
Position: 630-649
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (611-630)
Chemical type: Peptide from protein
Sequence: SNIMHSINGYVFDSLQLSVC
Position: 630-649
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (641-660)
Chemical type: Peptide from protein
Sequence: SIGAQTDFLSVFFSGYTFKH
Position: 660-679
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (641-660)
Chemical type: Peptide from protein
Sequence: SIGAQTDFLSVFFSGYTFKH
Position: 660-679
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (651-670)
Chemical type: Peptide from protein
Sequence: VFFSGYTFKHKMVYEDTLTL
Position: 670-689
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (651-670)
Chemical type: Peptide from protein
Sequence: VFFSGYTFKHKMVYEDTLTL
Position: 670-689
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (661-680)
Chemical type: Peptide from protein
Sequence: KMVYEDTLTLFPFSGETVFM
Position: 680-699
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (661-680)
Chemical type: Peptide from protein
Sequence: KMVYEDTLTLFPFSGETVFM
Position: 680-699
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (671-690)
Chemical type: Peptide from protein
Sequence: FPFSGETVFMSMENPGLWIL
Position: 690-709
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (671-690)
Chemical type: Peptide from protein
Sequence: FPFSGETVFMSMENPGLWIL
Position: 690-709
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (681-700)
Chemical type: Peptide from protein
Sequence: SMENPGLWILGCHNSDFRNR
Position: 700-719
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (681-700)
Chemical type: Peptide from protein
Sequence: SMENPGLWILGCHNSDFRNR
Position: 700-719
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (691-710)
Chemical type: Peptide from protein
Sequence: GCHNSDFRNRGMTALLKVSS
Position: 710-729
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (691-710)
Chemical type: Peptide from protein
Sequence: GCHNSDFRNRGMTALLKVSS
Position: 710-729
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative

Epitope: FVIII (701-720)
Chemical type: Peptide from protein
Sequence: GMTALLKVSSCDKNTGDYYE
Position: 720-739
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (701-720)
Chemical type: Peptide from protein
Sequence: GMTALLKVSSCDKNTGDYYE
Position: 720-739
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (711-730)
Chemical type: Peptide from protein
Sequence: CDKNTGDYYEDSYEDISAYL
Position: 730-749
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (711-730)
Chemical type: Peptide from protein
Sequence: CDKNTGDYYEDSYEDISAYL
Position: 730-749
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative

Epitope: FVIII (721-740)
Chemical type: Peptide from protein
Sequence: DSYEDISAYLLSKNNAIEPR
Position: 740-759
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (721-740)
Chemical type: Peptide from protein
Sequence: DSYEDISAYLLSKNNAIEPR
Position: 740-759
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (2181-2200)
Chemical type: Peptide from protein
Sequence: ESKAISDAQITASSYFTNMF
Position: 2200-2219
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (2181-2200)
Chemical type: Peptide from protein
Sequence: ESKAISDAQITASSYFTNMF
Position: 2200-2219
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (2191-2210)
Chemical type: Peptide from protein
Sequence: TASSYFTNMFATWSPSKARL
Position: 2210-2229
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (2191-2210)
Chemical type: Peptide from protein
Sequence: TASSYFTNMFATWSPSKARL
Position: 2210-2229
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (2201-2220)
Chemical type: Peptide from protein
Sequence: ATWSPSKARLHLQGRSNAWR
Position: 2220-2239
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (2201-2220)
Chemical type: Peptide from protein
Sequence: ATWSPSKARLHLQGRSNAWR
Position: 2220-2239
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (2211-2230)
Chemical type: Peptide from protein
Sequence: HLQGRSNAWRPQVNNPKEWL
Position: 2230-2249
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (2211-2230)
Chemical type: Peptide from protein
Sequence: HLQGRSNAWRPQVNNPKEWL
Position: 2230-2249
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (2221-2240)
Chemical type: Peptide from protein
Sequence: PQVNNPKEWLQVDFQKTMKV
Position: 2240-2259
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (2221-2240)
Chemical type: Peptide from protein
Sequence: PQVNNPKEWLQVDFQKTMKV
Position: 2240-2259
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (2231-2250)
Chemical type: Peptide from protein
Sequence: QVDFQKTMKVTGVTTQGVKS
Position: 2250-2269
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (2231-2250)
Chemical type: Peptide from protein
Sequence: QVDFQKTMKVTGVTTQGVKS
Position: 2250-2269
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (2241-2260)
Chemical type: Peptide from protein
Sequence: TGVTTQGVKSLLTSMYVKEF
Position: 2260-2279
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (2241-2260)
Chemical type: Peptide from protein
Sequence: TGVTTQGVKSLLTSMYVKEF
Position: 2260-2279
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (2251-2270)
Chemical type: Peptide from protein
Sequence: LLTSMYVKEFLISSSQDGHQ
Position: 2270-2289
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (2251-2270)
Chemical type: Peptide from protein
Sequence: LLTSMYVKEFLISSSQDGHQ
Position: 2270-2289
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (2261-2280)
Chemical type: Peptide from protein
Sequence: LISSSQDGHQWTLFFQNGKV
Position: 2280-2299
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (2261-2280)
Chemical type: Peptide from protein
Sequence: LISSSQDGHQWTLFFQNGKV
Position: 2280-2299
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (2271-2290)
Chemical type: Peptide from protein
Sequence: WTLFFQNGKVKVFQGNQDSF
Position: 2290-2309
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (2271-2290)
Chemical type: Peptide from protein
Sequence: WTLFFQNGKVKVFQGNQDSF
Position: 2290-2309
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (2281-2300)
Chemical type: Peptide from protein
Sequence: KVFQGNQDSFTPVVNSLDPP
Position: 2300-2319
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (2281-2300)
Chemical type: Peptide from protein
Sequence: KVFQGNQDSFTPVVNSLDPP
Position: 2300-2319
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (2291-2310)
Chemical type: Peptide from protein
Sequence: TPVVNSLDPPLLTRYLRIHP
Position: 2310-2329
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (2291-2310)
Chemical type: Peptide from protein
Sequence: TPVVNSLDPPLLTRYLRIHP
Position: 2310-2329
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (2301-2320)
Chemical type: Peptide from protein
Sequence: LLTRYLRIHPQSWVHQIALR
Position: 2320-2339
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (2301-2320)
Chemical type: Peptide from protein
Sequence: LLTRYLRIHPQSWVHQIALR
Position: 2320-2339
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (2321-2333)
Chemical type: Peptide from protein
Sequence: MEVLGCEAQDLY
Position: 2340-2351
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (2321-2333)
Chemical type: Peptide from protein
Sequence: MEVLGCEAQDLY
Position: 2340-2351
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: FVIII (2311-2330)
Chemical type: Peptide from protein
Sequence: QSWVHQIALRMEVLGCEAQD
Position: 2330-2349
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative
Host:  25-46 years

Epitope: FVIII (2311-2330)
Chemical type: Peptide from protein
Sequence: QSWVHQIALRMEVLGCEAQD
Position: 2330-2349
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive