Reference: Raianna F Fantin; Meng Yuan; Seok-Chan Park; Bailey Bozarth; Hallie Cohn; Maxinne Ignacio; Patricia Earl; Alesandro Civljak; Gabriel Laghlali; Ding Zhang; Xueyong Zhu; Jameson Crandell; Valter Monteiro; Jordan J Clark; Catherine Cotter; Martin Burkhardt; Gagandeep Singh; Prajakta Warang; Juan García-Bernalt Diego; Komal Srivastava; Luz A Lugo; Lauren Pischel; Inci Yildirim; Saad B Omer; Daniel da Silva; Florian Krammer; Goran Bajic; Viviana Simon; Michael Schotsaert; Carolina Lucas; Ian A Wilson; Bernard Moss; Camila H Coelho. "Human monoclonal antibodies targeting A35 protect from death caused by mpox." Cell (2025).

Epitope: Epitope of EV35-2 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: E: Y116, S118, D121, D150, D165, Q167, D170, S172, Q173, E174, V175, R176, K177; F: Y116, D150, T160, T162, T163, D165, Y166, Q167, D168, S169, V175
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.2
Host: M 30-39 years

Epitope: Epitope of EV35-2 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: E: Y116, S118, D121, D150, D165, Q167, D170, S172, Q173, E174, V175, R176, K177; F: Y116, D150, T160, T162, T163, D165, Y166, Q167, D168, S169, V175
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Host: M 30-39 years

Epitope: Epitope of EV35-2 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: E: Y116, S118, D121, D150, D165, Q167, D170, S172, Q173, E174, V175, R176, K177; F: Y116, D150, T160, T162, T163, D165, Y166, Q167, D168, S169, V175
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Host: M 30-39 years

Epitope: Epitope of EV35-2 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: E: Y116, S118, D121, D150, D165, Q167, D170, S172, Q173, E174, V175, R176, K177; F: Y116, D150, T160, T162, T163, D165, Y166, Q167, D168, S169, V175
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive-Low
Host: M 27-58 years

Epitope: Epitope of EV35-2 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: E: Y116, S118, D121, D150, D165, Q167, D170, S172, Q173, E174, V175, R176, K177; F: Y116, D150, T160, T162, T163, D165, Y166, Q167, D168, S169, V175
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Host: M 21-61 years

Epitope: Epitope of EV35-2 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: E: Y116, S118, D121, D150, D165, Q167, D170, S172, Q173, E174, V175, R176, K177; F: Y116, D150, T160, T162, T163, D165, Y166, Q167, D168, S169, V175
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Host: M 30-39 years

Epitope: Epitope of EV35-2 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: E: Y116, S118, D121, D150, D165, Q167, D170, S172, Q173, E174, V175, R176, K177; F: Y116, D150, T160, T162, T163, D165, Y166, Q167, D168, S169, V175
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Host: M 30-39 years

Epitope: Epitope of EV35-2 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: E: Y116, S118, D121, D150, D165, Q167, D170, S172, Q173, E174, V175, R176, K177; F: Y116, D150, T160, T162, T163, D165, Y166, Q167, D168, S169, V175
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Host: M 30-39 years

Epitope: Epitope of EV35-2 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: E: Y116, S118, D121, D150, D165, Q167, D170, S172, Q173, E174, V175, R176, K177; F: Y116, D150, T160, T162, T163, D165, Y166, Q167, D168, S169, V175
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.92
Host: M 30-39 years

Epitope: Epitope of EV35-2 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: E: Y116, S118, D121, D150, D165, Q167, D170, S172, Q173, E174, V175, R176, K177; F: Y116, D150, T160, T162, T163, D165, Y166, Q167, D168, S169, V175
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.6
Host: M 30-39 years

Epitope: Epitope of EV35-2 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: E: Y116, S118, D121, D150, D165, Q167, D170, S172, Q173, E174, V175, R176, K177; F: Y116, D150, T160, T162, T163, D165, Y166, Q167, D168, S169, V175
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive-Low
Host:  20-46 years

Epitope: Epitope of EV35-2 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: E: Y116, S118, D121, D150, D165, Q167, D170, S172, Q173, E174, V175, R176, K177; F: Y116, D150, T160, T162, T163, D165, Y166, Q167, D168, S169, V175
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Host: M 30-39 years

Epitope: Epitope of EV35-2 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: E: Y116, S118, D121, D150, D165, Q167, D170, S172, Q173, E174, V175, R176, K177; F: Y116, D150, T160, T162, T163, D165, Y166, Q167, D168, S169, V175
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Host: M 30-39 years

Epitope: Epitope of EV35-2 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: E: Y116, S118, D121, D150, D165, Q167, D170, S172, Q173, E174, V175, R176, K177; F: Y116, D150, T160, T162, T163, D165, Y166, Q167, D168, S169, V175
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive-Low
Host:  40-62 years

Epitope: Epitope of EV35-6 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: G: L112, D115, Y116, K117, Y147, E149, D150, T151, D170, Q173, V175, R176, K177, F179; I: Y116, D146, Y147, E149, D150, T151, T163, E174, V175, R176, K177
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.18
Host: M 30-39 years

Epitope: Epitope of EV35-6 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: G: L112, D115, Y116, K117, Y147, E149, D150, T151, D170, Q173, V175, R176, K177, F179; I: Y116, D146, Y147, E149, D150, T151, T163, E174, V175, R176, K177
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive-Low
Host: M 27-58 years

Epitope: Epitope of EV35-6 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: G: L112, D115, Y116, K117, Y147, E149, D150, T151, D170, Q173, V175, R176, K177, F179; I: Y116, D146, Y147, E149, D150, T151, T163, E174, V175, R176, K177
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Host: M 21-61 years

Epitope: Epitope of EV35-6 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: G: L112, D115, Y116, K117, Y147, E149, D150, T151, D170, Q173, V175, R176, K177, F179; I: Y116, D146, Y147, E149, D150, T151, T163, E174, V175, R176, K177
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.8
Host: M 30-39 years

Epitope: Epitope of EV35-6 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: G: L112, D115, Y116, K117, Y147, E149, D150, T151, D170, Q173, V175, R176, K177, F179; I: Y116, D146, Y147, E149, D150, T151, T163, E174, V175, R176, K177
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.7
Host: M 30-39 years

Epitope: Epitope of EV35-6 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: G: L112, D115, Y116, K117, Y147, E149, D150, T151, D170, Q173, V175, R176, K177, F179; I: Y116, D146, Y147, E149, D150, T151, T163, E174, V175, R176, K177
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive-Low
Host:  40-62 years

Epitope: Epitope of EV35-6 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: G: L112, D115, Y116, K117, Y147, E149, D150, T151, D170, Q173, V175, R176, K177, F179; I: Y116, D146, Y147, E149, D150, T151, T163, E174, V175, R176, K177
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Negative
Host:  20-46 years

Epitope: Epitope of EV35-6 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: G: L112, D115, Y116, K117, Y147, E149, D150, T151, D170, Q173, V175, R176, K177, F179; I: Y116, D146, Y147, E149, D150, T151, T163, E174, V175, R176, K177
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Host: M 30-39 years

Epitope: Epitope of EV35-6 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: G: L112, D115, Y116, K117, Y147, E149, D150, T151, D170, Q173, V175, R176, K177, F179; I: Y116, D146, Y147, E149, D150, T151, T163, E174, V175, R176, K177
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Host: M 30-39 years

Epitope: Epitope of EV35-6 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: G: L112, D115, Y116, K117, Y147, E149, D150, T151, D170, Q173, V175, R176, K177, F179; I: Y116, D146, Y147, E149, D150, T151, T163, E174, V175, R176, K177
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Host: M 30-39 years

Epitope: Epitope of EV35-6 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: G: L112, D115, Y116, K117, Y147, E149, D150, T151, D170, Q173, V175, R176, K177, F179; I: Y116, D146, Y147, E149, D150, T151, T163, E174, V175, R176, K177
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Host: M 30-39 years

Epitope: Epitope of EV35-6 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: G: L112, D115, Y116, K117, Y147, E149, D150, T151, D170, Q173, V175, R176, K177, F179; I: Y116, D146, Y147, E149, D150, T151, T163, E174, V175, R176, K177
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Host: M 30-39 years

Epitope: Epitope of EV35-6 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: G: L112, D115, Y116, K117, Y147, E149, D150, T151, D170, Q173, V175, R176, K177, F179; I: Y116, D146, Y147, E149, D150, T151, T163, E174, V175, R176, K177
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Host: M 30-39 years

Epitope: Epitope of EV35-6 on MPXV A35R
Chemical type: Region on multi-chain protein
Discontinuous residues: G: L112, D115, Y116, K117, Y147, E149, D150, T151, D170, Q173, V175, R176, K177, F179; I: Y116, D146, Y147, E149, D150, T151, T163, E174, V175, R176, K177
Source molecule (GenBank): AAN78222.1
Assay category: BCell
Result: Positive
Host: M 30-39 years