Reference: Maya F Kotturi; Jason Botten; Matt Maybeno; John Sidney; Jean Glenn; Huynh-Hoa Bui; Carla Oseroff; Shane Crotty; Bjoern Peters; Howard Grey; Daniel M Altmann; Michael J Buchmeier; Alessandro Sette. "Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage." Immunome research (2010).

Epitope: GTOV GPC  131-145
Chemical type: Peptide from protein
Sequence: KGSPEFDWILGWTIK
Position: 131-145
Source molecule (GenBank): AAN09938.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GTOV GPC  131-145
Chemical type: Peptide from protein
Sequence: KGSPEFDWILGWTIK
Position: 131-145
Source molecule (GenBank): AAN09938.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.7

Epitope: GTOV L  181-195
Chemical type: Peptide from protein
Sequence: DQEYHRLIHSLSKTS
Position: 181-195
Source molecule (GenBank): AAQ55254.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GTOV L  181-195
Chemical type: Peptide from protein
Sequence: DQEYHRLIHSLSKTS
Position: 181-195
Source molecule (GenBank): AAQ55254.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.34

Epitope: GTOV L  391-405
Chemical type: Peptide from protein
Sequence: RVLDILVARRLLLKK
Position: 391-405
Source molecule (GenBank): AAQ55254.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GTOV L  391-405
Chemical type: Peptide from protein
Sequence: RVLDILVARRLLLKK
Position: 391-405
Source molecule (GenBank): AAQ55254.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.19

Epitope: GTOV L  1826-1840
Chemical type: Peptide from protein
Sequence: IQLVFSSMINPLVIT
Position: 1826-1840
Source molecule (GenBank): AAQ55254.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GTOV L  1826-1840
Chemical type: Peptide from protein
Sequence: IQLVFSSMINPLVIT
Position: 1826-1840
Source molecule (GenBank): AAQ55254.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GTOV L  1826-1840
Chemical type: Peptide from protein
Sequence: IQLVFSSMINPLVIT
Position: 1826-1840
Source molecule (GenBank): AAQ55254.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.23

Epitope: GTOV NP  166-180
Chemical type: Peptide from protein
Sequence: KLNNQFGSMPALTIA
Position: 166-180
Source molecule (GenBank): AAN05424.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GTOV NP  166-180
Chemical type: Peptide from protein
Sequence: KLNNQFGSMPALTIA
Position: 166-180
Source molecule (GenBank): AAN05424.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.12

Epitope: GTOV NP  191-205
Chemical type: Peptide from protein
Sequence: NNVVQALTSLGLLYT
Position: 191-205
Source molecule (GenBank): AAN05424.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GTOV NP  191-205
Chemical type: Peptide from protein
Sequence: NNVVQALTSLGLLYT
Position: 191-205
Source molecule (GenBank): AAN05424.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.29

Epitope: GTOV NP  236-250
Chemical type: Peptide from protein
Sequence: ISGYNFSLSAAVKAG
Position: 236-250
Source molecule (GenBank): AAN05424.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GTOV NP  236-250
Chemical type: Peptide from protein
Sequence: ISGYNFSLSAAVKAG
Position: 236-250
Source molecule (GenBank): AAN05424.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GTOV NP  236-250
Chemical type: Peptide from protein
Sequence: ISGYNFSLSAAVKAG
Position: 236-250
Source molecule (GenBank): AAN05424.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.12

Epitope: GTOV NP  541-555
Chemical type: Peptide from protein
Sequence: IPIQLLPNTLVFQAK
Position: 541-555
Source molecule (GenBank): AAN05424.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GTOV NP  541-555
Chemical type: Peptide from protein
Sequence: IPIQLLPNTLVFQAK
Position: 541-555
Source molecule (GenBank): AAN05424.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.25

Epitope: JUNV GPC  46-60
Chemical type: Peptide from protein
Sequence: FFVFLALAGRSCTEE
Position: 46-60
Source molecule (GenBank): AAB65462.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: JUNV GPC  46-60
Chemical type: Peptide from protein
Sequence: FFVFLALAGRSCTEE
Position: 46-60
Source molecule (GenBank): AAB65462.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.23

Epitope: JUNV L  381-395
Chemical type: Peptide from protein
Sequence: VGQMLMLVNDRLLDI
Position: 381-395
Source molecule (GenBank): AAP44543.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: JUNV L  381-395
Chemical type: Peptide from protein
Sequence: VGQMLMLVNDRLLDI
Position: 381-395
Source molecule (GenBank): AAP44543.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.21

Epitope: JUNV L 391-405
Chemical type: Peptide from protein
Sequence: RLLDILEAIKLIRKK
Position: 391-405
Source molecule (GenBank): AAP44543.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: JUNV L 391-405
Chemical type: Peptide from protein
Sequence: RLLDILEAIKLIRKK
Position: 391-405
Source molecule (GenBank): AAP44543.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.48

Epitope: JUNV L 411-425
Chemical type: Peptide from protein
Sequence: KWVQMCSRTLKNSHQ
Position: 411-425
Source molecule (GenBank): AAP44543.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: JUNV L 411-425
Chemical type: Peptide from protein
Sequence: KWVQMCSRTLKNSHQ
Position: 411-425
Source molecule (GenBank): AAP44543.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.1

Epitope: JUNV L 1491-1505
Chemical type: Peptide from protein
Sequence: MFIRNCARKVFNDIK
Position: 1491-1505
Source molecule (GenBank): AAP44543.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: JUNV L 1491-1505
Chemical type: Peptide from protein
Sequence: MFIRNCARKVFNDIK
Position: 1491-1505
Source molecule (GenBank): AAP44543.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.0

Epitope: JUNV L 1711-1725
Chemical type: Peptide from protein
Sequence: NKNFFWAVKPKAVRQ
Position: 1711-1725
Source molecule (GenBank): AAP44543.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: JUNV L 1711-1725
Chemical type: Peptide from protein
Sequence: NKNFFWAVKPKAVRQ
Position: 1711-1725
Source molecule (GenBank): AAP44543.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.06

Epitope: LASV GPC 236-250
Chemical type: Peptide from protein
Sequence: PSPIGYLGLLSQRTR
Position: 236-250
Source molecule (GenBank): AAG41802.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LASV GPC 236-250
Chemical type: Peptide from protein
Sequence: PSPIGYLGLLSQRTR
Position: 236-250
Source molecule (GenBank): AAG41802.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.14

Epitope: LASV GPC 241-255
Chemical type: Peptide from protein
Sequence: YLGLLSQRTRDIYIS
Position: 241-255
Source molecule (GenBank): AAG41802.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LASV GPC 241-255
Chemical type: Peptide from protein
Sequence: YLGLLSQRTRDIYIS
Position: 241-255
Source molecule (GenBank): AAG41802.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.29

Epitope: LCMV GPC 421-435
Chemical type: Peptide from protein
Sequence: LRKDYIKRQGSTPLA
Position: 421-435
Source molecule (GenBank): ABI96818.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LCMV GPC 421-435
Chemical type: Peptide from protein
Sequence: LRKDYIKRQGSTPLA
Position: 421-435
Source molecule (GenBank): ABI96818.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LCMV GPC 421-435
Chemical type: Peptide from protein
Sequence: LRKDYIKRQGSTPLA
Position: 421-435
Source molecule (GenBank): ABI96818.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LCMV GPC 421-435
Chemical type: Peptide from protein
Sequence: LRKDYIKRQGSTPLA
Position: 421-435
Source molecule (GenBank): ABI96818.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 4.8

Epitope: LCMV L 256-270
Chemical type: Peptide from protein
Sequence: RNFQKVNPEGLIKEF
Position: 256-270
Source molecule (GenBank): NP_694845.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LCMV L 256-270
Chemical type: Peptide from protein
Sequence: RNFQKVNPEGLIKEF
Position: 256-270
Source molecule (GenBank): NP_694845.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 5.6

Epitope: LCMV L  946-960
Chemical type: Peptide from protein
Sequence: HLRKVILSEISFHLV
Position: 946-960
Source molecule (GenBank): NP_694845.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LCMV L  946-960
Chemical type: Peptide from protein
Sequence: HLRKVILSEISFHLV
Position: 946-960
Source molecule (GenBank): NP_694845.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LCMV L  946-960
Chemical type: Peptide from protein
Sequence: HLRKVILSEISFHLV
Position: 946-960
Source molecule (GenBank): NP_694845.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LCMV L  946-960
Chemical type: Peptide from protein
Sequence: HLRKVILSEISFHLV
Position: 946-960
Source molecule (GenBank): NP_694845.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LCMV L  946-960
Chemical type: Peptide from protein
Sequence: HLRKVILSEISFHLV
Position: 946-960
Source molecule (GenBank): NP_694845.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.1

Epitope: LCMV NP 6-20
Chemical type: Peptide from protein
Sequence: EVKSFQWTQALRREL
Position: 6-20
Source molecule (GenBank): AAL01686.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LCMV NP 6-20
Chemical type: Peptide from protein
Sequence: EVKSFQWTQALRREL
Position: 6-20
Source molecule (GenBank): AAL01686.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LCMV NP 6-20
Chemical type: Peptide from protein
Sequence: EVKSFQWTQALRREL
Position: 6-20
Source molecule (GenBank): AAL01686.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LCMV NP 6-20
Chemical type: Peptide from protein
Sequence: EVKSFQWTQALRREL
Position: 6-20
Source molecule (GenBank): AAL01686.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 49.0

Epitope: LCMV NP 521-535
Chemical type: Peptide from protein
Sequence: MDCIIFESASKARLP
Position: 521-535
Source molecule (GenBank): AAL01686.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LCMV NP 521-535
Chemical type: Peptide from protein
Sequence: MDCIIFESASKARLP
Position: 521-535
Source molecule (GenBank): AAL01686.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 4.4

Epitope: MACV GPC  96-110
Chemical type: Peptide from protein
Sequence: NSFYYMKGGVNTFLI
Position: 96-110
Source molecule (GenBank): AAS77634.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MACV GPC  96-110
Chemical type: Peptide from protein
Sequence: NSFYYMKGGVNTFLI
Position: 96-110
Source molecule (GenBank): AAS77634.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MACV GPC  96-110
Chemical type: Peptide from protein
Sequence: NSFYYMKGGVNTFLI
Position: 96-110
Source molecule (GenBank): AAS77634.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.21

Epitope: MACV GPC  446-460
Chemical type: Peptide from protein
Sequence: ASLFLHLVGIPTHRH
Position: 446-460
Source molecule (GenBank): AAN09942.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MACV GPC  446-460
Chemical type: Peptide from protein
Sequence: ASLFLHLVGIPTHRH
Position: 446-460
Source molecule (GenBank): AAN09942.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.13

Epitope: MACV L  391-405
Chemical type: Peptide from protein
Sequence: DRVLDILEAVKLIRK
Position: 391-405
Source molecule (GenBank): AAP44547.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MACV L  391-405
Chemical type: Peptide from protein
Sequence: DRVLDILEAVKLIRK
Position: 391-405
Source molecule (GenBank): AAP44547.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.48

Epitope: MACV L  636-650
Chemical type: Peptide from protein
Sequence: RYFLMAFANQIHHID
Position: 636-650
Source molecule (GenBank): AAP44547.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MACV L  636-650
Chemical type: Peptide from protein
Sequence: RYFLMAFANQIHHID
Position: 636-650
Source molecule (GenBank): AAP44547.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.24

Epitope: MACV L  866-880
Chemical type: Peptide from protein
Sequence: DYLILKNLTGLVSAG
Position: 866-880
Source molecule (GenBank): AAP44547.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MACV L  866-880
Chemical type: Peptide from protein
Sequence: DYLILKNLTGLVSAG
Position: 866-880
Source molecule (GenBank): AAP44547.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.21

Epitope: MACV L  1491-1505
Chemical type: Peptide from protein
Sequence: TSFIRNCARKVFNDI
Position: 1491-1505
Source molecule (GenBank): AAP44547.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MACV L  1491-1505
Chemical type: Peptide from protein
Sequence: TSFIRNCARKVFNDI
Position: 1491-1505
Source molecule (GenBank): AAP44547.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.11

Epitope: MACV L  1711-1725
Chemical type: Peptide from protein
Sequence: NNQNFFWAVKPKVVR
Position: 1711-1725
Source molecule (GenBank): AAP44547.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MACV L  1711-1725
Chemical type: Peptide from protein
Sequence: NNQNFFWAVKPKVVR
Position: 1711-1725
Source molecule (GenBank): AAP44547.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.7

Epitope: MACV NP  191-205
Chemical type: Peptide from protein
Sequence: NSVVQALTSLGLLYT
Position: 191-205
Source molecule (GenBank): P26578.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MACV NP  191-205
Chemical type: Peptide from protein
Sequence: NSVVQALTSLGLLYT
Position: 191-205
Source molecule (GenBank): P26578.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.78

Epitope: MACV Z 21-35
Chemical type: Peptide from protein
Sequence: PSAEFRRTAPPSLYG
Position: 21-35
Source molecule (GenBank): NP_899214.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MACV Z 21-35
Chemical type: Peptide from protein
Sequence: PSAEFRRTAPPSLYG
Position: 21-35
Source molecule (GenBank): NP_899214.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.0

Epitope: SABV GPC  26-40
Chemical type: Peptide from protein
Sequence: VSLIAALKGMINLWK
Position: 26-40
Source molecule (GenBank): AAC55091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SABV GPC  26-40
Chemical type: Peptide from protein
Sequence: VSLIAALKGMINLWK
Position: 26-40
Source molecule (GenBank): AAC55091.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.47

Epitope: SABV GPC  441-455
Chemical type: Peptide from protein
Sequence: FLHLVGFPTHRHIRG
Position: 441-455
Source molecule (GenBank): AAC55091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SABV GPC  441-455
Chemical type: Peptide from protein
Sequence: FLHLVGFPTHRHIRG
Position: 441-455
Source molecule (GenBank): AAC55091.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 0.09

Epitope: WWAV GPC  46-60
Chemical type: Peptide from protein
Sequence: FIVFLLLAGRSCSYK
Position: 46-60
Source molecule (GenBank): AAN09950.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: WWAV GPC  46-60
Chemical type: Peptide from protein
Sequence: FIVFLLLAGRSCSYK
Position: 46-60
Source molecule (GenBank): AAN09950.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.2

Epitope: WWAV GPC  386-400
Chemical type: Peptide from protein
Sequence: FRNQWLLESDHLISE
Position: 386-400
Source molecule (GenBank): AAN09950.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: WWAV GPC  386-400
Chemical type: Peptide from protein
Sequence: FRNQWLLESDHLISE
Position: 386-400
Source molecule (GenBank): AAN09950.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.6