Reference: Bibiana Bielekova; Myong-Hee Sung; Nadja Kadom; Richard Simon; Henry McFarland; Roland Martin. "Expansion and functional relevance of high-avidity myelin-specific CD4+ T cells in multiple sclerosis." Journal of immunology (Baltimore, Md. : 1950) (2004).

Epitope: MBP<sub>13–32</sub>
Chemical type: Peptide from protein
Sequence: KYLATASTMDHARHGFLPRH
Position: 23-42
Source molecule (GenBank): AAH08749.2
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>13–32</sub>
Chemical type: Peptide from protein
Sequence: KYLATASTMDHARHGFLPRH
Position: 23-42
Source molecule (GenBank): AAH08749.2
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  27-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>13–32</sub>
Chemical type: Peptide from protein
Sequence: KYLATASTMDHARHGFLPRH
Position: 23-42
Source molecule (GenBank): AAH08749.2
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>13–32</sub>
Chemical type: Peptide from protein
Sequence: KYLATASTMDHARHGFLPRH
Position: 23-42
Source molecule (GenBank): AAH08749.2
Assay category: TCell
Result: Positive-High
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>83–99</sub>
Chemical type: Peptide from protein
Sequence: ENPVVHFFKNIVTPRTP
Position: 93-109
Source molecule (GenBank): AAH08749.2
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>83–99</sub>
Chemical type: Peptide from protein
Sequence: ENPVVHFFKNIVTPRTP
Position: 93-109
Source molecule (GenBank): AAH08749.2
Assay category: TCell
Result: Positive-High
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>83–99</sub>
Chemical type: Peptide from protein
Sequence: ENPVVHFFKNIVTPRTP
Position: 93-109
Source molecule (GenBank): AAH08749.2
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>83–99</sub>
Chemical type: Peptide from protein
Sequence: ENPVVHFFKNIVTPRTP
Position: 93-109
Source molecule (GenBank): AAH08749.2
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  27-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>111–129</sub>
Chemical type: Peptide from protein
Sequence: LSRFSWGAEGQRPGFGYGG
Position: 121-139
Source molecule (GenBank): AAH08749.2
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  27-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>111–129</sub>
Chemical type: Peptide from protein
Sequence: LSRFSWGAEGQRPGFGYGG
Position: 121-139
Source molecule (GenBank): AAH08749.2
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>111–129</sub>
Chemical type: Peptide from protein
Sequence: LSRFSWGAEGQRPGFGYGG
Position: 121-139
Source molecule (GenBank): AAH08749.2
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>111–129</sub>
Chemical type: Peptide from protein
Sequence: LSRFSWGAEGQRPGFGYGG
Position: 121-139
Source molecule (GenBank): AAH08749.2
Assay category: TCell
Result: Positive-High
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>131–155</sub>
Chemical type: Peptide from protein
Sequence: ASDYKSAHKGLKGVDAQGTLSKIFK
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  27-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>131–155</sub>
Chemical type: Peptide from protein
Sequence: ASDYKSAHKGLKGVDAQGTLSKIFK
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>131–155</sub>
Chemical type: Peptide from protein
Sequence: ASDYKSAHKGLKGVDAQGTLSKIFK
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>131–155</sub>
Chemical type: Peptide from protein
Sequence: ASDYKSAHKGLKGVDAQGTLSKIFK
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>146–170</sub>
Chemical type: Peptide from protein
Sequence: AQGTLSKIFKLGGRDSRSGSPMARR
Position: 156-180
Source molecule (GenBank): AAH08749.2
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  27-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>146–170</sub>
Chemical type: Peptide from protein
Sequence: AQGTLSKIFKLGGRDSRSGSPMARR
Position: 156-180
Source molecule (GenBank): AAH08749.2
Assay category: TCell
Result: Positive-High
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>146–170</sub>
Chemical type: Peptide from protein
Sequence: AQGTLSKIFKLGGRDSRSGSPMARR
Position: 156-180
Source molecule (GenBank): AAH08749.2
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>146–170</sub>
Chemical type: Peptide from protein
Sequence: AQGTLSKIFKLGGRDSRSGSPMARR
Position: 156-180
Source molecule (GenBank): AAH08749.2
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>89–106</sub>
Chemical type: Peptide from protein
Sequence: GFYTTGAVRQIFGDYKTT
Position: 90-107
Source molecule (GenBank): AAA60117.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  27-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>89–106</sub>
Chemical type: Peptide from protein
Sequence: GFYTTGAVRQIFGDYKTT
Position: 90-107
Source molecule (GenBank): AAA60117.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>89–106</sub>
Chemical type: Peptide from protein
Sequence: GFYTTGAVRQIFGDYKTT
Position: 90-107
Source molecule (GenBank): AAA60117.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>89–106</sub>
Chemical type: Peptide from protein
Sequence: GFYTTGAVRQIFGDYKTT
Position: 90-107
Source molecule (GenBank): AAA60117.1
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>139–154</sub>
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKFVGI
Position: 140-155
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  27-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>139–154</sub>
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKFVGI
Position: 140-155
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive-High
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>139–154</sub>
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKFVGI
Position: 140-155
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive-High
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>139–154</sub>
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKFVGI
Position: 140-155
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>178–197</sub>
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSKTSASIG
Position: 179-198
Source molecule (GenBank): AAA60117.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>178–197</sub>
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSKTSASIG
Position: 179-198
Source molecule (GenBank): AAA60117.1
Assay category: TCell
Result: Positive-High
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>178–197</sub>
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSKTSASIG
Position: 179-198
Source molecule (GenBank): AAA60117.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  27-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>178–197</sub>
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSKTSASIG
Position: 179-198
Source molecule (GenBank): AAA60117.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>190–208</sub>
Chemical type: Peptide from protein
Sequence: SKTSASIGSLCADARMYGVLP
Position: 191-211
Source molecule (GenBank): AAA60117.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  27-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>190–208</sub>
Chemical type: Peptide from protein
Sequence: SKTSASIGSLCADARMYGVLP
Position: 191-211
Source molecule (GenBank): AAA60117.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>190–208</sub>
Chemical type: Peptide from protein
Sequence: SKTSASIGSLCADARMYGVLP
Position: 191-211
Source molecule (GenBank): AAA60117.1
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>190–208</sub>
Chemical type: Peptide from protein
Sequence: SKTSASIGSLCADARMYGVLP
Position: 191-211
Source molecule (GenBank): AAA60117.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>1–20</sub>
Chemical type: Peptide from protein
Sequence: GQFRVIGPRHPIRALVGDEV
Position: 30-49
Source molecule (GenBank): Q16653.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  27-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>1–20</sub>
Chemical type: Peptide from protein
Sequence: GQFRVIGPRHPIRALVGDEV
Position: 30-49
Source molecule (GenBank): Q16653.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>1–20</sub>
Chemical type: Peptide from protein
Sequence: GQFRVIGPRHPIRALVGDEV
Position: 30-49
Source molecule (GenBank): Q16653.1
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>1–20</sub>
Chemical type: Peptide from protein
Sequence: GQFRVIGPRHPIRALVGDEV
Position: 30-49
Source molecule (GenBank): Q16653.1
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>11–30</sub>
Chemical type: Peptide from protein
Sequence: PIRALVGDEVELPCRISPGK
Position: 40-59
Source molecule (GenBank): Q16653.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  27-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>11–30</sub>
Chemical type: Peptide from protein
Sequence: PIRALVGDEVELPCRISPGK
Position: 40-59
Source molecule (GenBank): Q16653.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>11–30</sub>
Chemical type: Peptide from protein
Sequence: PIRALVGDEVELPCRISPGK
Position: 40-59
Source molecule (GenBank): Q16653.1
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>11–30</sub>
Chemical type: Peptide from protein
Sequence: PIRALVGDEVELPCRISPGK
Position: 40-59
Source molecule (GenBank): Q16653.1
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>35–55</sub>
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): Q16653.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 339 341
Host:  27-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>35–55</sub>
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): Q16653.1
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>35–55</sub>
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): Q16653.1
Assay category: TCell
Result: Positive-High
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>35–55</sub>
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): Q16653.1
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CNP<sub>343–373</sub>
Chemical type: Peptide from protein
Sequence: EVGELSRGKLYSLGNGRWMLTLAKNMEVRAI
Position: 363-393
Source molecule (GenBank): NP_149124.3
Assay category: TCell
Result: Positive-High
MHC allele types: 339 341
Host:  27-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CNP<sub>343–373</sub>
Chemical type: Peptide from protein
Sequence: EVGELSRGKLYSLGNGRWMLTLAKNMEVRAI
Position: 363-393
Source molecule (GenBank): NP_149124.3
Assay category: TCell
Result: Positive-High
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CNP<sub>343–373</sub>
Chemical type: Peptide from protein
Sequence: EVGELSRGKLYSLGNGRWMLTLAKNMEVRAI
Position: 363-393
Source molecule (GenBank): NP_149124.3
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CNP<sub>343–373</sub>
Chemical type: Peptide from protein
Sequence: EVGELSRGKLYSLGNGRWMLTLAKNMEVRAI
Position: 363-393
Source molecule (GenBank): NP_149124.3
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 339 341
Host:  21-56 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo