Reference: Minako Oshima; Philip Deitiker; Joseph Jankovic; M Zouhair Atassi. "The Regions on the Light Chain of Botulinum Neurotoxin Type A Recognized by T Cells from Toxin-Treated Cervical Dystonia Patients. The Complete Human T-Cell Recognition Map of the Toxin Molecule." Immunological investigations (2018).

Epitope: L1
Chemical type: Peptide from protein
Sequence: MPFVNKQFNYKDPVNGVDI
Position: 1-19
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L3
Chemical type: Peptide from protein
Sequence: QMQPVKAFKIHNKIWVIPE
Position: 29-47
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L4
Chemical type: Peptide from protein
Sequence: WVIPERDTFTNPEEGDLNP
Position: 43-61
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L5
Chemical type: Peptide from protein
Sequence: GDLNPPPEAKQVPVSYYDS
Position: 57-75
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L6
Chemical type: Peptide from protein
Sequence: SYYDSTYLSTDNEKDNYLK
Position: 71-89
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L7
Chemical type: Peptide from protein
Sequence: DNYLKGVTKLFERIYSTDL
Position: 85-103
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L9
Chemical type: Peptide from protein
Sequence: RGIPFWGGSTIDTELKVID
Position: 113-131
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L10
Chemical type: Peptide from protein
Sequence: LKVIDTNCINVIQPDGSYR
Position: 127-145
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L11
Chemical type: Peptide from protein
Sequence: DGSYRSEELNLVIIGPSAD
Position: 141-159
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L12
Chemical type: Peptide from protein
Sequence: GPSADIIQFECKSFGHEVL
Position: 155-173
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L13
Chemical type: Peptide from protein
Sequence: GHEVLNLTRNGYGSTQYIR
Position: 169-187
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L14
Chemical type: Peptide from protein
Sequence: TQYIRFSPDFTFGFEESLE
Position: 183-201
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive-High
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L15
Chemical type: Peptide from protein
Sequence: EESLEVDTNPLLGAGKFAT
Position: 197-215
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L16
Chemical type: Peptide from protein
Sequence: GKFATDPAVTLAHELIHAG
Position: 211-229
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L17
Chemical type: Peptide from protein
Sequence: LIHAGHRLYGIAINPNRVF
Position: 225-243
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive-High
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L18
Chemical type: Peptide from protein
Sequence: PNRVFKVNTNAYYEMSGLE
Position: 239-257
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L19
Chemical type: Peptide from protein
Sequence: MSGLEVSFEELRTFGGHDA
Position: 253-271
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive-High
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L20
Chemical type: Peptide from protein
Sequence: GGHDAKFIDSLQENEFRLY
Position: 267-285
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L21
Chemical type: Peptide from protein
Sequence: EFRLYYYNKFKDIASTLNK
Position: 281-299
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L23
Chemical type: Peptide from protein
Sequence: SLQYMKNVFKEKYLLSEDT
Position: 309-327
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L24
Chemical type: Peptide from protein
Sequence: LSEDTSGKFSVDKLKFDKL
Position: 323-341
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L25
Chemical type: Peptide from protein
Sequence: KFDKLYKMLTEIYTEDNFV
Position: 337-355
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L26
Chemical type: Peptide from protein
Sequence: EDNFVKFFKVLNRKTYLNF
Position: 351-369
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L27
Chemical type: Peptide from protein
Sequence: TYLNFDKAVFKINIVPKVN
Position: 365-383
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L30
Chemical type: Peptide from protein
Sequence: EINNMNFTKLKNFTGLFEF
Position: 407-425
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L32
Chemical type: Peptide from protein
Sequence: ITSKTKSLDKGYNKALNDL
Position: 435-453
Source molecule (GenBank): ABS38337.1
Assay category: TCell
Result: Positive-Low
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo