Reference: Fei-Xiang Ding; Fang Wang; Yi-Ming Lu; Ka Li; Kai-Hui Wang; Xiao-Wen He; Shu-Han Sun. "Multiepitope peptide-loaded virus-like particles as a vaccine against hepatitis B virus-related hepatocellular carcinoma." Hepatology (Baltimore, Md.) (2009).

Epitope: HBx<sub>(115-123)</sub>
Chemical type: Peptide from protein
Sequence: CLFKDWEEL
Position: 115-123
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBx<sub>(115-123)</sub>
Chemical type: Peptide from protein
Sequence: CLFKDWEEL
Position: 115-123
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBx<sub>(115-123)</sub>
Chemical type: Peptide from protein
Sequence: CLFKDWEEL
Position: 115-123
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HBx<sub>(115-123)</sub>
Chemical type: Peptide from protein
Sequence: CLFKDWEEL
Position: 115-123
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBx<sub>(115-123)</sub>
Chemical type: Peptide from protein
Sequence: CLFKDWEEL
Position: 115-123
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks

Epitope: HBx<sub>(115-123)</sub>
Chemical type: Peptide from protein
Sequence: CLFKDWEEL
Position: 115-123
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HBx<sub>(115-123)</sub>
Chemical type: Peptide from protein
Sequence: CLFKDWEEL
Position: 115-123
Source molecule (GenBank): AAP06597.1
Assay category: MhcBinding
Result: Positive

Epitope: HBx<sub>(133-141)</sub>
Chemical type: Peptide from protein
Sequence: VLGGCRHKL
Position: 133-141
Source molecule (GenBank): AAP06597.1
Assay category: MhcBinding
Result: Positive

Epitope: HBx<sub>(7-15)</sub>
Chemical type: Peptide from protein
Sequence: CQLDPARDV
Position: 7-15
Source molecule (GenBank): AAP06597.1
Assay category: MhcBinding
Result: Positive

Epitope: HBx<sub>(92-100)</sub>
Chemical type: Peptide from protein
Sequence: VLHKRTLGL
Position: 92-100
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBx<sub>(92-100)</sub>
Chemical type: Peptide from protein
Sequence: VLHKRTLGL
Position: 92-100
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBx<sub>(92-100)</sub>
Chemical type: Peptide from protein
Sequence: VLHKRTLGL
Position: 92-100
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBx<sub>(92-100)</sub>
Chemical type: Peptide from protein
Sequence: VLHKRTLGL
Position: 92-100
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks

Epitope: HBx<sub>(92-100)</sub>
Chemical type: Peptide from protein
Sequence: VLHKRTLGL
Position: 92-100
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HBx<sub>(92-100)</sub>
Chemical type: Peptide from protein
Sequence: VLHKRTLGL
Position: 92-100
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HBx<sub>(92-100)</sub>
Chemical type: Peptide from protein
Sequence: VLHKRTLGL
Position: 92-100
Source molecule (GenBank): AAP06597.1
Assay category: MhcBinding
Result: Positive

Epitope: HBx<sub>(140-148)</sub>
Chemical type: Peptide from protein
Sequence: KLVCSPAPC
Position: 140-148
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBx<sub>(140-148)</sub>
Chemical type: Peptide from protein
Sequence: KLVCSPAPC
Position: 140-148
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks

Epitope: HBx<sub>(140-148)</sub>
Chemical type: Peptide from protein
Sequence: KLVCSPAPC
Position: 140-148
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBx<sub>(140-148)</sub>
Chemical type: Peptide from protein
Sequence: KLVCSPAPC
Position: 140-148
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBx<sub>(140-148)</sub>
Chemical type: Peptide from protein
Sequence: KLVCSPAPC
Position: 140-148
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HBx<sub>(140-148)</sub>
Chemical type: Peptide from protein
Sequence: KLVCSPAPC
Position: 140-148
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HBx<sub>(140-148)</sub>
Chemical type: Peptide from protein
Sequence: KLVCSPAPC
Position: 140-148
Source molecule (GenBank): AAP06597.1
Assay category: MhcBinding
Result: Positive

Epitope: HBx<sub>(15-23)</sub>
Chemical type: Peptide from protein
Sequence: VLCLRPVGA
Position: 15-23
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBx<sub>(15-23)</sub>
Chemical type: Peptide from protein
Sequence: VLCLRPVGA
Position: 15-23
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HBx<sub>(15-23)</sub>
Chemical type: Peptide from protein
Sequence: VLCLRPVGA
Position: 15-23
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HBx<sub>(15-23)</sub>
Chemical type: Peptide from protein
Sequence: VLCLRPVGA
Position: 15-23
Source molecule (GenBank): AAP06597.1
Assay category: MhcBinding
Result: Negative

Epitope: HBx<sub>(97-105)</sub>
Chemical type: Peptide from protein
Sequence: TLGLAAMST
Position: 97-105
Source molecule (GenBank): AAP06597.1
Assay category: MhcBinding
Result: Positive

Epitope: HBx<sub>(102-110)</sub>
Chemical type: Peptide from protein
Sequence: AMSTTDLEA
Position: 102-110
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HBx<sub>(102-110)</sub>
Chemical type: Peptide from protein
Sequence: AMSTTDLEA
Position: 102-110
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HBx<sub>(102-110)</sub>
Chemical type: Peptide from protein
Sequence: AMSTTDLEA
Position: 102-110
Source molecule (GenBank): AAP06597.1
Assay category: MhcBinding
Result: Positive

Epitope: HBx<sub>(52-60)</sub>
Chemical type: Peptide from protein
Sequence: HLSLRGLPV
Position: 52-60
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBx<sub>(52-60)</sub>
Chemical type: Peptide from protein
Sequence: HLSLRGLPV
Position: 52-60
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks

Epitope: HBx<sub>(52-60)</sub>
Chemical type: Peptide from protein
Sequence: HLSLRGLPV
Position: 52-60
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBx<sub>(52-60)</sub>
Chemical type: Peptide from protein
Sequence: HLSLRGLPV
Position: 52-60
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBx<sub>(52-60)</sub>
Chemical type: Peptide from protein
Sequence: HLSLRGLPV
Position: 52-60
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HBx<sub>(52-60)</sub>
Chemical type: Peptide from protein
Sequence: HLSLRGLPV
Position: 52-60
Source molecule (GenBank): AAP06597.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HBx<sub>(52-60)</sub>
Chemical type: Peptide from protein
Sequence: HLSLRGLPV
Position: 52-60
Source molecule (GenBank): AAP06597.1
Assay category: MhcBinding
Result: Positive

Epitope: HBx<Sub>(84-92)</sub>
Chemical type: Peptide from protein
Sequence: NAHQVLPKV
Position: 84-92
Source molecule (GenBank): AAP06597.1
Assay category: MhcBinding
Result: Negative

Epitope: HBV core-derived HBc<Sub>(18-27)</sub>
Chemical type: Peptide from protein
Sequence: YLSGANLNL
Assay category: MhcBinding
Result: Positive

Epitope: Irrelevant peptide CAP-1
Chemical type: Peptide from protein
Sequence: SIINFEKL
Position: 258-265
Source molecule (GenBank): P01012.2
Assay category: MhcBinding
Result: Positive