Reference: Anouk L Feitsma; Ellen I H van der Voort; Kees L M C Franken; Hanane el Bannoudi; Berendina G Elferink; Jan W Drijfhout; Tom W J Huizinga; René R P de Vries; René E M Toes; A Ioan-Facsinay. "Identification of citrullinated vimentin peptides as T cell epitopes in HLA-DR4-positive patients with rheumatoid arthritis." Arthritis and rheumatism (2010).

Epitope: Peptide 1
Chemical type: Peptide from protein
Sequence: MSTRSVSSSSYRRMFGGPG
Position: 1-19
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 2
Chemical type: Peptide from protein
Sequence: RSVSSSSYRRMFGGPGTAS
Position: 4-22
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 3
Chemical type: Peptide from protein
Sequence: MFGGPGTASRPSSSRSYVT
Position: 14-32
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 4
Chemical type: Peptide from protein
Sequence: GTASRPSSSRSYVTTSTRT
Position: 19-37
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 6
Chemical type: Peptide from protein
Sequence: RTYSLGSALRPSTSRSLYA
Position: 36-54
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 7
Chemical type: Peptide from protein
Sequence: GSALRPSTSRSLYASSPGG
Position: 41-59
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 8
Chemical type: Peptide from protein
Sequence: SSPGGVYATRSSAVRLRSS
Position: 55-73
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 9
Chemical type: Peptide from protein
Sequence: YATRSSAVRLRSSVPGVRL
Position: 61-79
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 12
Chemical type: Peptide from protein
Sequence: EKVELQELNDRFANYIDKV
Position: 103-121
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 13
Chemical type: Peptide from protein
Sequence: RFANYIDKVRFLEQQNKIL
Position: 113-131
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 14
Chemical type: Peptide from protein
Sequence: EQLKGQGKSRLGDLYEEEM
Position: 136-154
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 16
Chemical type: Peptide from protein
Sequence: VDQLTNDKARVEVERDNLA
Position: 161-179
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 17
Chemical type: Peptide from protein
Sequence: NDKARVEVERDNLAEDIMR
Position: 166-184
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 18
Chemical type: Peptide from protein
Sequence: DNLAEDIMRLREKLQEEML
Position: 176-194
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 19
Chemical type: Peptide from protein
Sequence: EKLQEEMLQREEAENTLQS
Position: 187-205
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 20
Chemical type: Peptide from protein
Sequence: EAENTLQSFRQDVDNASLA
Position: 198-216
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 21
Chemical type: Peptide from protein
Sequence: DNASLARLDLERKVESLQE
Position: 211-229
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 22
Chemical type: Peptide from protein
Sequence: KPDLTAALRDVRQQYESVA
Position: 262-280
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 23
Chemical type: Peptide from protein
Sequence: FADLSEAANRNNDALRQAK
Position: 295-313
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 24
Chemical type: Peptide from protein
Sequence: AANRNNDALRQAKQESTEY
Position: 301-319
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 25
Chemical type: Peptide from protein
Sequence: QAKQESTEYRRQVQSLTCE
Position: 311-329
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 26
Chemical type: Peptide from protein
Sequence: KGTNESLERQMREMEENFA
Position: 334-352
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 27
Chemical type: Peptide from protein
Sequence: AANYQDTIGRLQDEIQNMK
Position: 355-373
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 28
Chemical type: Peptide from protein
Sequence: QNMKEEMARHLREYQDLLN
Position: 370-388
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 29
Chemical type: Peptide from protein
Sequence: ALDIEIATYRKLLEGEESR
Position: 392-410
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 30
Chemical type: Peptide from protein
Sequence: RKLLEGEESRISLPLPNFS
Position: 401-419
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 31
Chemical type: Peptide from protein
Sequence: LPNFSSLNLRETNLDSLPL
Position: 415-433
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 31
Chemical type: Peptide from protein
Sequence: LPNFSSLNLRETNLDSLPL
Position: 415-433
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 31
Chemical type: Peptide from protein
Sequence: LPNFSSLNLRETNLDSLPL
Position: 415-433
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  38-75 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Peptide 31
Chemical type: Peptide from protein
Sequence: LPNFSSLNLRETNLDSLPL
Position: 415-433
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Peptide 32
Chemical type: Peptide from protein
Sequence: LPLVDTHSKRTLLIKTVET
Position: 431-449
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Peptide 33
Chemical type: Peptide from protein
Sequence: TLLIKTVETRDGQVINETS
Position: 441-459
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Non-cit Peptide 31
Chemical type: Peptide from protein
Sequence: LPNFSSLNLRETNLDSLPL
Position: 415-433
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive-Low
Host:  38-75 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Non-cit Peptide 31
Chemical type: Peptide from protein
Sequence: LPNFSSLNLRETNLDSLPL
Position: 415-433
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated