Reference: Dody Avichezer; Gregory I Liou; Chi-Chao Chan; Giavonni M Lewis; Barbara Wiggert; Larry A Donoso; John M Nickerson; Mary Alice Crawford; Rachel R Caspi. "Interphotoreceptor retinoid-binding protein (IRBP)-deficient C57BL/6 mice have enhanced immunological and immunopathogenic responses to IRBP and an altered recognition of IRBP epitopes." Journal of autoimmunity (2003).

Epitope: IRBP 1-20
Chemical type: Peptide from protein
Sequence: GPTHLFQPSLVLDMAKVLLD
Position: 17-36
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: IRBP 1-20
Chemical type: Peptide from protein
Sequence: GPTHLFQPSLVLDMAKVLLD
Position: 17-36
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 11-30
Chemical type: Peptide from protein
Sequence: VLDMAKVLLDNYCFPENLLG
Position: 27-46
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 21-40
Chemical type: Peptide from protein
Sequence: NYCFPENLLGMQEAIQQAIK
Position: 37-56
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 31-50
Chemical type: Peptide from protein
Sequence: MQEAIQQAIKSHEILSISDP
Position: 47-66
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 41-60
Chemical type: Peptide from protein
Sequence: SHEILSISDPQTLASVLTAG
Position: 57-76
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 61-80
Chemical type: Peptide from protein
Sequence: VQSSLNDPRLVISYEPSTPE
Position: 77-96
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 71-90
Chemical type: Peptide from protein
Sequence: VISYEPSTPEPPPQVPALTS
Position: 87-106
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 81-100
Chemical type: Peptide from protein
Sequence: PPPQVPALTSLSEEELLAWL
Position: 97-116
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 91-110
Chemical type: Peptide from protein
Sequence: LSEEELLAWLQRGLRHEVLE
Position: 107-126
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 111-130
Chemical type: Peptide from protein
Sequence: GNVGYLRVDSVPGQEVLSMM
Position: 127-146
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 121-140
Chemical type: Peptide from protein
Sequence: VPGQEVLSMMGEFLVAHVWG
Position: 137-156
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 141-160
Chemical type: Peptide from protein
Sequence: NLMGTSALVLDLRHCTGGQV
Position: 157-176
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 161-180
Chemical type: Peptide from protein
Sequence: SGIPYIISYLHPGNTILHVD
Position: 177-196
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 171-190
Chemical type: Peptide from protein
Sequence: HPGNTILHVDTIYNRPSNTT
Position: 187-206
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 191-210
Chemical type: Peptide from protein
Sequence: TEIWTLPQVLGERYGADKDV
Position: 207-226
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 201-220
Chemical type: Peptide from protein
Sequence: GERYGADKDVVVLTSSQTRG
Position: 217-236
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 211-230
Chemical type: Peptide from protein
Sequence: VVLTSSQTRGVAEDIAHILK
Position: 227-246
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 221-240
Chemical type: Peptide from protein
Sequence: VAEDIAHILKQMRRAIVVGE
Position: 237-256
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 231-250
Chemical type: Peptide from protein
Sequence: QMRRAIVVGERTGGGALDLR
Position: 247-266
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 251-270
Chemical type: Peptide from protein
Sequence: KLRIGESDFFFTVPVSRSLG
Position: 267-286
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 261-280
Chemical type: Peptide from protein
Sequence: FTVPVSRSLGPLGGGSQTWE
Position: 277-296
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 271-290
Chemical type: Peptide from protein
Sequence: PLGGGSQTWEGSGVLPCVGT
Position: 287-306
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 281-300
Chemical type: Peptide from protein
Sequence: GSGVLPCVGTPAEQALEKAL
Position: 297-316
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 291-310
Chemical type: Peptide from protein
Sequence: PAEQALEKALAILTLRSALP
Position: 307-326
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 301-320
Chemical type: Peptide from protein
Sequence: AILTLRSALPGVVHCLQEVL
Position: 317-336
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 311-330
Chemical type: Peptide from protein
Sequence: GVVHCLQEVLKDYYTLVDRV
Position: 327-346
Source molecule (GenBank): AAA59188.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo