Reference: Stina L Wickström; Tanja Lövgren; Michael Volkmar; Bruce Reinhold; Jonathan S Duke-Cohan; Laura Hartmann; Janina Rebmann; Anja Mueller; Jeroen Melief; Roeltje Maas; Maarten Ligtenberg; Johan Hansson; Rienk Offringa; Barbara Seliger; Isabel Poschke; Ellis L Reinherz; Rolf Kiessling. "Cancer Neoepitopes for Immunotherapy: Discordance Between Tumor-Infiltrating T Cell Reactivity and Tumor MHC Peptidome Display." Frontiers in immunology (2019).

Epitope: KADA-KDELR2-mut
Chemical type: Peptide, no natural source
Sequence: ILWIFSIYL
Assay category: TCell
Result: Positive
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KADA-KDELR2-mut
Chemical type: Peptide, no natural source
Sequence: ILWIFSIYL
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 73 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KADA-KDELR2-mut
Chemical type: Peptide, no natural source
Sequence: ILWIFSIYL
Assay category: TCell
Result: Positive-High
MHC allele types: 143
Host: M 73 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: KADA-KDELR2-mut
Chemical type: Peptide, no natural source
Sequence: ILWIFSIYL
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 73 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: KADA-CCT4-mut
Chemical type: Peptide, no natural source
Sequence: FLLDSCTKL
Assay category: TCell
Result: Positive
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KADA-CCT4-mut
Chemical type: Peptide, no natural source
Sequence: FLLDSCTKL
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 73 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KADA-CCT4-mut
Chemical type: Peptide, no natural source
Sequence: FLLDSCTKL
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 73 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: KADA-CCT4-mut
Chemical type: Peptide, no natural source
Sequence: FLLDSCTKL
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 143

Epitope: KADA-CCT4-mut
Chemical type: Peptide, no natural source
Sequence: FLLDSCTKL
Assay category: MhcBinding
Result: Positive

Epitope: KADA-MYLIP-mut
Chemical type: Peptide, no natural source
Sequence: RLDAVLMEV
Assay category: TCell
Result: Positive
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KADA-MYLIP-mut
Chemical type: Peptide, no natural source
Sequence: RLDAVLMEV
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 73 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KADA-MYLIP-mut
Chemical type: Peptide, no natural source
Sequence: RLDAVLMEV
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 73 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: KADA-MYLIP-mut
Chemical type: Peptide, no natural source
Sequence: RLDAVLMEV
Assay category: MhcBinding
Result: Positive

Epitope: KADA-SVIL-mut-9
Chemical type: Peptide, no natural source
Sequence: YLTDKDFEF
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 73 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KADA-SVIL-mut-9
Chemical type: Peptide, no natural source
Sequence: YLTDKDFEF
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 73 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: KADA-SVIL-mut-9
Chemical type: Peptide, no natural source
Sequence: YLTDKDFEF
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 73 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: KADA-SVIL-mut-9
Chemical type: Peptide, no natural source
Sequence: YLTDKDFEF
Assay category: MhcBinding
Result: Positive

Epitope: KADA-WDR75-mut
Chemical type: Peptide, no natural source
Sequence: FMFVNSLLL
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 73 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KADA-WDR75-mut
Chemical type: Peptide, no natural source
Sequence: FMFVNSLLL
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 73 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: KADA-WDR75-mut
Chemical type: Peptide, no natural source
Sequence: FMFVNSLLL
Assay category: MhcBinding
Result: Positive

Epitope: ANRU-ETV6-mut-9
Chemical type: Peptide, no natural source
Sequence: VLWDYVYQL
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 39 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: ANRU-ETV6-mut-9
Chemical type: Peptide, no natural source
Sequence: VLWDYVYQL
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 39 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: ANRU-ETV6-mut-9
Chemical type: Peptide, no natural source
Sequence: VLWDYVYQL
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 39 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ANRU-ETV6-mut-9
Chemical type: Peptide, no natural source
Sequence: VLWDYVYQL
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 39 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: ANRU-ETV6-mut-9
Chemical type: Peptide, no natural source
Sequence: VLWDYVYQL
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 143

Epitope: ANRU-ETV6-mut-9
Chemical type: Peptide, no natural source
Sequence: VLWDYVYQL
Assay category: MhcBinding
Result: Positive

Epitope: ANRU-ETV6-mut-10
Chemical type: Peptide, no natural source
Sequence: VLWDYVYQLL
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 39 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: ANRU-ETV6-mut-10
Chemical type: Peptide, no natural source
Sequence: VLWDYVYQLL
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 39 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: ANRU-ETV6-mut-10
Chemical type: Peptide, no natural source
Sequence: VLWDYVYQLL
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 39 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: ANRU-ETV6-mut-10
Chemical type: Peptide, no natural source
Sequence: VLWDYVYQLL
Assay category: MhcBinding
Result: Positive

Epitope: ANRU-NUP210-mut
Chemical type: Peptide, no natural source
Sequence: AIDAALTFV
Assay category: TCell
Result: Positive
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ANRU-NUP210-mut
Chemical type: Peptide, no natural source
Sequence: AIDAALTFV
Assay category: TCell
Result: Negative
MHC allele types: 143
Host: M 39 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: ANRU-NUP210-mut
Chemical type: Peptide, no natural source
Sequence: AIDAALTFV
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 39 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: ANRU-NUP210-mut
Chemical type: Peptide, no natural source
Sequence: AIDAALTFV
Assay category: TCell
Result: Positive-High
MHC allele types: 143
Host: M 39 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: ANRU-NUP210-mut
Chemical type: Peptide, no natural source
Sequence: AIDAALTFV
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 39 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ANRU-NUP210-mut
Chemical type: Peptide, no natural source
Sequence: AIDAALTFV
Assay category: MhcBinding
Result: Positive

Epitope: KADA-KDELR2-wt
Chemical type: Peptide from protein
Sequence: ILWTFSIYL
Position: 118-126
Source molecule (GenBank): NP_006846.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Host: M 73 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: KADA-CCT4-wt
Chemical type: Peptide from protein
Sequence: SLLDSCTKL
Position: 115-123
Source molecule (GenBank): NP_006421.2
Assay category: TCell
Result: Negative
MHC allele types: 143
Host: M 73 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: KADA-CCT4-wt
Chemical type: Peptide from protein
Sequence: SLLDSCTKL
Position: 115-123
Source molecule (GenBank): NP_006421.2
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 143

Epitope: KADA-CCT4-wt
Chemical type: Peptide from protein
Sequence: SLLDSCTKL
Position: 115-123
Source molecule (GenBank): NP_006421.2
Assay category: MhcBinding
Result: Positive

Epitope: KADA-MYLIP-wt
Chemical type: Peptide from protein
Sequence: RPDAVLMEV
Position: 7-15
Source molecule (GenBank): XP_016866278.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Host: M 73 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: KADA-MYLIP-wt
Chemical type: Peptide from protein
Sequence: RPDAVLMEV
Position: 7-15
Source molecule (GenBank): XP_016866278.1
Assay category: MhcBinding
Result: Negative

Epitope: KADA-SVIL-wt-9
Chemical type: Peptide from protein
Sequence: YLTDEDFEF
Position: 2179-2187
Source molecule (GenBank): AAD14682.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Host: M 73 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: KADA-SVIL-wt-9
Chemical type: Peptide from protein
Sequence: YLTDEDFEF
Position: 2179-2187
Source molecule (GenBank): AAD14682.1
Assay category: MhcBinding
Result: Positive

Epitope: KADA-SVIL-wt-10
Chemical type: Peptide from protein
Sequence: YLTDEDFEFA
Position: 2179-2188
Source molecule (GenBank): AAD14682.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Host: M 73 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: KADA-SVIL-wt-10
Chemical type: Peptide from protein
Sequence: YLTDEDFEFA
Position: 2179-2188
Source molecule (GenBank): AAD14682.1
Assay category: MhcBinding
Result: Positive

Epitope: KADA-WDR75-wt
Chemical type: Peptide from protein
Sequence: SMFVNSLLL
Position: 527-535
Source molecule (GenBank): XP_024308936.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Host: M 73 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: KADA-WDR75-wt
Chemical type: Peptide from protein
Sequence: SMFVNSLLL
Position: 527-535
Source molecule (GenBank): XP_024308936.1
Assay category: MhcBinding
Result: Positive

Epitope: ANRU-ETV6-wt-9
Chemical type: Peptide from protein
Sequence: LLWDYVYQL
Position: 148-156
Source molecule (GenBank): NP_001193967.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Host: M 39 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: ANRU-ETV6-wt-9
Chemical type: Peptide from protein
Sequence: LLWDYVYQL
Position: 148-156
Source molecule (GenBank): NP_001193967.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 143

Epitope: ANRU-ETV6-wt-9
Chemical type: Peptide from protein
Sequence: LLWDYVYQL
Position: 148-156
Source molecule (GenBank): NP_001193967.1
Assay category: MhcBinding
Result: Positive

Epitope: ANRU-ETV6-wt-10
Chemical type: Peptide from protein
Sequence: LLWDYVYQLL
Position: 148-157
Source molecule (GenBank): NP_001193967.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Host: M 39 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: ANRU-ETV6-wt-10
Chemical type: Peptide from protein
Sequence: LLWDYVYQLL
Position: 148-157
Source molecule (GenBank): NP_001193967.1
Assay category: MhcBinding
Result: Positive

Epitope: ANRU-MART-wt-10
Chemical type: Peptide from protein
Sequence: EAAGIGILTV
Position: 26-35
Source molecule (GenBank): NP_005502.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Host: M 39 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: ANRU-MART-wt-10
Chemical type: Peptide from protein
Sequence: EAAGIGILTV
Position: 26-35
Source molecule (GenBank): NP_005502.1
Assay category: MhcBinding
Result: Positive

Epitope: KADA-AGPS-mut
Chemical type: Peptide, no natural source
Sequence: ALWDRVVDL
Assay category: TCell
Result: Positive
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KADA-AGPS-mut
Chemical type: Peptide, no natural source
Sequence: ALWDRVVDL
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 73 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KADA-AGPS-mut
Chemical type: Peptide, no natural source
Sequence: ALWDRVVDL
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 143

Epitope: KADA-AGPS-mut
Chemical type: Peptide, no natural source
Sequence: ALWDRVVDL
Assay category: MhcBinding
Result: Positive

Epitope: KADA-ENC1-mut
Chemical type: Peptide, no natural source
Sequence: YLSELLQTV
Assay category: TCell
Result: Positive
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KADA-ENC1-mut
Chemical type: Peptide, no natural source
Sequence: YLSELLQTV
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 73 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KADA-ENC1-mut
Chemical type: Peptide, no natural source
Sequence: YLSELLQTV
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 143

Epitope: KADA-ENC1-mut
Chemical type: Peptide, no natural source
Sequence: YLSELLQTV
Assay category: MhcBinding
Result: Positive

Epitope: KADA-SVIL-mut-10
Chemical type: Peptide, no natural source
Sequence: YLTDKDFEFA
Assay category: TCell
Result: Positive-Low
MHC allele types: 143
Host: M 73 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: KADA-SVIL-mut-10
Chemical type: Peptide, no natural source
Sequence: YLTDKDFEFA
Assay category: MhcBinding
Result: Positive

Epitope: ANRU-MART-mut-10
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ANRU-MART-mut-10
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 39 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: ANRU-MART-mut-10
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 39 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: ANRU-MART-mut-10
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 39 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: ANRU-MART-mut-10
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 39 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ANRU-MART-mut-10
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: MhcBinding
Result: Positive

Epitope: ANRU-gp100-mut
Chemical type: Peptide, no natural source
Sequence: IMDQVPFSV
Assay category: TCell
Result: Negative
MHC allele types: 143
Host: M 39 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown

Epitope: ANRU-gp100-mut
Chemical type: Peptide, no natural source
Sequence: IMDQVPFSV
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 39 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: ANRU-gp100-mut
Chemical type: Peptide, no natural source
Sequence: IMDQVPFSV
Assay category: MhcBinding
Result: Positive

Epitope: KADA-AGPS-wt
Chemical type: Peptide from protein
Sequence: APWDRVVDL
Position: 532-540
Source molecule (GenBank): NP_003650.1
Assay category: MhcBinding
Result: Negative

Epitope: KADA-ENC1-wt
Chemical type: Peptide from protein
Sequence: YLPELLQTV
Position: 228-236
Source molecule (GenBank): NP_003624.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 143

Epitope: KADA-ENC1-wt
Chemical type: Peptide from protein
Sequence: YLPELLQTV
Position: 228-236
Source molecule (GenBank): NP_003624.1
Assay category: MhcBinding
Result: Positive

Epitope: KADA-Flu M1-wt
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
MHC allele types: 143
Host: M 73 years
Cell type: tumor infiltrating lymphocyte
Tissue: skin
Culture conditions: Other / Unknown