Reference: Kilyna A Nguyen; Zhihui Liu; John S Davies; Crystal P McIntosh; Lindsey M Draper; Scott M Norberg; Zachary Rae; Sooraj R Achar; Gregoire Altan-Bonnet; Ling Zhang; Xiaolin Wu; Thomas J Meyer; Michael C Kelly; Naomi Taylor; Christian S Hinrichs; Kazusa Ishii. "CD22 TCR-engineered T cells exert antileukemia cytotoxicity without causing inflammatory responses." Science advances (2025).

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive-Low
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive-Low
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: CD22 p228-236
Chemical type: Peptide from protein
Sequence: FLSNDTVQL
Position: 228-236
Source molecule (GenBank): P20273.2
Assay category: MhcBinding
Result: Positive

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive-Intermediate
Host: F 
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive-Intermediate
Host: F 
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HPV-16 E7 p11-19
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: MhcBinding
Result: Positive-Low

Epitope: KKLC1 p52-60
Chemical type: Peptide from protein
Sequence: NTDNNLAVY
Position: 52-60
Source molecule (GenBank): Q5H943.1
Assay category: MhcBinding
Result: Negative

Epitope: UHRF1
Chemical type: Peptide from protein
Sequence: RLNDTIQLL
Position: 64-72
Source molecule (GenBank): Q96T88.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: TMM68
Chemical type: Peptide from protein
Sequence: LISDETYNI
Position: 90-98
Source molecule (GenBank): E5RJN2.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: WHAL1
Chemical type: Peptide from protein
Sequence: MLAQETLQL
Position: 69-77
Source molecule (GenBank): Q1A5X7.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell
Tissue: blood
Culture conditions: Engineered