Reference: Pavlo Gilchuk; Charles D Murin; Robert W Cross; Philipp A Ilinykh; Kai Huang; Natalia Kuzmina; Viktoriya Borisevich; Krystle N Agans; Joan B Geisbert; Seth J Zost; Rachel S Nargi; Rachel E Sutton; Naveenchandra Suryadevara; Robin G Bombardi; Robert H Carnahan; Alexander Bukreyev; Thomas W Geisbert; Andrew B Ward; James E Crowe. "Pan-ebolavirus protective therapy by two multifunctional human antibodies." Cell (2021).

Epitope: Epitope of rEBOV-442 Fab on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: T223, E231, L233, V242, Q243, L256, I260, S267, N268, T269, T270, G271, K272, L273, I274, W275, K276, V277, N278
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of rEBOV-442 Fab on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: T223, E231, L233, V242, Q243, L256, I260, S267, N268, T269, T270, G271, K272, L273, I274, W275, K276, V277, N278
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-442 Fab on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: T223, E231, L233, V242, Q243, L256, I260, S267, N268, T269, T270, G271, K272, L273, I274, W275, K276, V277, N278
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-442 Fab on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: T223, E231, L233, V242, Q243, L256, I260, S267, N268, T269, T270, G271, K272, L273, I274, W275, K276, V277, N278
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-442 Fab on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: T223, E231, L233, V242, Q243, L256, I260, S267, N268, T269, T270, G271, K272, L273, I274, W275, K276, V277, N278
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-442 Fab on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: T223, E231, L233, V242, Q243, L256, I260, S267, N268, T269, T270, G271, K272, L273, I274, W275, K276, V277, N278
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-442 Fab on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: T223, E231, L233, V242, Q243, L256, I260, S267, N268, T269, T270, G271, K272, L273, I274, W275, K276, V277, N278
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-442 Fab on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: T223, E231, L233, V242, Q243, L256, I260, S267, N268, T269, T270, G271, K272, L273, I274, W275, K276, V277, N278
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-442 Fab on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: T223, E231, L233, V242, Q243, L256, I260, S267, N268, T269, T270, G271, K272, L273, I274, W275, K276, V277, N278
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-442 Fab on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: T223, E231, L233, V242, Q243, L256, I260, S267, N268, T269, T270, G271, K272, L273, I274, W275, K276, V277, N278
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-442 Fab on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: T223, E231, L233, V242, Q243, L256, I260, S267, N268, T269, T270, G271, K272, L273, I274, W275, K276, V277, N278
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-442 Fab on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: T223, E231, L233, V242, Q243, L256, I260, S267, N268, T269, T270, G271, K272, L273, I274, W275, K276, V277, N278
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-442 Fab on EBOV GP
Chemical type: Discontinuous protein residues
Discontinuous residues: T223, E231, L233, V242, Q243, L256, I260, S267, N268, T269, T270, G271, K272, L273, I274, W275, K276, V277, N278
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-515 Fab on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E71, W104, A105, E106, R136; D: N506, Q508, P509, K510, C511, N512, P513, N514, H516, E545, G546, L547, M548, H549, N550, Q551, C556
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-515 Fab on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E71, W104, A105, E106, R136; D: N506, Q508, P509, K510, C511, N512, P513, N514, H516, E545, G546, L547, M548, H549, N550, Q551, C556
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-515 Fab on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E71, W104, A105, E106, R136; D: N506, Q508, P509, K510, C511, N512, P513, N514, H516, E545, G546, L547, M548, H549, N550, Q551, C556
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-515 Fab on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E71, W104, A105, E106, R136; D: N506, Q508, P509, K510, C511, N512, P513, N514, H516, E545, G546, L547, M548, H549, N550, Q551, C556
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-515 Fab on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E71, W104, A105, E106, R136; D: N506, Q508, P509, K510, C511, N512, P513, N514, H516, E545, G546, L547, M548, H549, N550, Q551, C556
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-515 Fab on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E71, W104, A105, E106, R136; D: N506, Q508, P509, K510, C511, N512, P513, N514, H516, E545, G546, L547, M548, H549, N550, Q551, C556
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-515 Fab on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E71, W104, A105, E106, R136; D: N506, Q508, P509, K510, C511, N512, P513, N514, H516, E545, G546, L547, M548, H549, N550, Q551, C556
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-515 Fab on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E71, W104, A105, E106, R136; D: N506, Q508, P509, K510, C511, N512, P513, N514, H516, E545, G546, L547, M548, H549, N550, Q551, C556
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-515 Fab on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E71, W104, A105, E106, R136; D: N506, Q508, P509, K510, C511, N512, P513, N514, H516, E545, G546, L547, M548, H549, N550, Q551, C556
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-515 Fab on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E71, W104, A105, E106, R136; D: N506, Q508, P509, K510, C511, N512, P513, N514, H516, E545, G546, L547, M548, H549, N550, Q551, C556
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of rEBOV-515 Fab on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E71, W104, A105, E106, R136; D: N506, Q508, P509, K510, C511, N512, P513, N514, H516, E545, G546, L547, M548, H549, N550, Q551, C556
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-515 Fab on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E71, W104, A105, E106, R136; D: N506, Q508, P509, K510, C511, N512, P513, N514, H516, E545, G546, L547, M548, H549, N550, Q551, C556
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive

Epitope: Epitope of rEBOV-515 Fab on EBOV GP
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E71, W104, A105, E106, R136; D: N506, Q508, P509, K510, C511, N512, P513, N514, H516, E545, G546, L547, M548, H549, N550, Q551, C556
Source molecule (GenBank): AKG65268.1
Assay category: BCell
Result: Positive