Reference: A Thrasyvoulides; M Sakarellos-Daitsiotis; G Philippou; A Souvatzoglou; C Sakarellos; P Lymberi. "B-cell autoepitopes on the acetylcholinesterase-homologous region of human thyroglobulin: association with Graves' disease and thyroid eye disease." European journal of endocrinology / European Federation of Endocrine Societies (2001).

Epitope: hTg 1
Chemical type: Peptide from protein
Sequence: LLSYEASVPSVPISTHGRLL
Position: 2191-2210
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 2
Chemical type: Peptide from protein
Sequence: ISTHGRLLGRSQAIQVGTSW
Position: 2203-2222
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 3
Chemical type: Peptide from protein
Sequence: AIQVGTSWKQVDQFLGVPYA
Position: 2215-2234
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 4
Chemical type: Peptide from protein
Sequence: QFLGVPYAAPPLAERHFQAP
Position: 2226-2245
Source molecule (GenBank): CAA29104.1
Assay category: BCell
Result: Positive

Epitope: hTg 5
Chemical type: Peptide from protein
Sequence: AERHFQAPEPLNWTGSWDAS
Position: 2238-2257
Source molecule (GenBank): CAA29104.1
Assay category: BCell
Result: Positive

Epitope: hTg 6
Chemical type: Peptide from protein
Sequence: WTGSWDASKPRASCWQPGTR
Position: 2251-2270
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 8
Chemical type: Peptide from protein
Sequence: PGVSEDCLYLNVFIPQNVAP
Position: 2275-2294
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 9
Chemical type: Peptide from protein
Sequence: FIPQNVAPNASVLVFFHNTM
Position: 2287-2306
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Negative

Epitope: hTg 10
Chemical type: Peptide from protein
Sequence: LVFFHNTMDREESEGWPAID
Position: 2299-2318
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 11
Chemical type: Peptide from protein
Sequence: SEGWPAIDGSFLAAVGNLIV
Position: 2311-2330
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 12
Chemical type: Peptide from protein
Sequence: AAVGNLIVVTASYRVGVFGF
Position: 2323-2342
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 13
Chemical type: Peptide from protein
Sequence: YRVGVFGFLSSGSGEVSGNW
Position: 2335-2354
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 14
Chemical type: Peptide from protein
Sequence: SGEVSGNWGLLDQVAALTWV
Position: 2347-2366
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 15
Chemical type: Peptide from protein
Sequence: QVAALTWVQTHIRGFGGDPR
Position: 2359-2378
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Negative
Host:  15-78 years

Epitope: hTg 15
Chemical type: Peptide from protein
Sequence: QVAALTWVQTHIRGFGGDPR
Position: 2359-2378
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Negative
Host:  20 to 75

Epitope: hTg 15
Chemical type: Peptide from protein
Sequence: QVAALTWVQTHIRGFGGDPR
Position: 2359-2378
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive
Host:  17-84 years

Epitope: hTg 16
Chemical type: Peptide from protein
Sequence: RGFGGDPRRVSLAADRGGAD
Position: 2371-2390
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 17
Chemical type: Peptide from protein
Sequence: AADRGGADVASIHLLTARAT
Position: 2383-2402
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 18
Chemical type: Peptide from protein
Sequence: HLLTARATNSQLFRRAVLMG
Position: 2395-2414
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 19
Chemical type: Peptide from protein
Sequence: FRRAVLMGGSALSPAAVISH
Position: 2407-2426
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 20
Chemical type: Peptide from protein
Sequence: SPAAVISHERAQQQAIALAK
Position: 2419-2438
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 21
Chemical type: Peptide from protein
Sequence: QQAIALAKEVSCPMSSSQEV
Position: 2431-2450
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Negative

Epitope: hTg 22
Chemical type: Peptide from protein
Sequence: PMSSSQEVVSCLRQKPANVL
Position: 2443-2462
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Negative

Epitope: hTg 23
Chemical type: Peptide from protein
Sequence: RQKPANVLNDAQTKLLAVSG
Position: 2455-2474
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 25
Chemical type: Peptide from protein
Sequence: WGPVIDGHFLREPPARALKR
Position: 2479-2498
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 26
Chemical type: Peptide from protein
Sequence: PPARALKRSLWVEVDLLIGS
Position: 2491-2510
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive
Host:  17 to 84

Epitope: hTg 26
Chemical type: Peptide from protein
Sequence: PPARALKRSLWVEVDLLIGS
Position: 2491-2510
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive
Host:  15-78 years

Epitope: hTg 26
Chemical type: Peptide from protein
Sequence: PPARALKRSLWVEVDLLIGS
Position: 2491-2510
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive
Host:  17 to 84

Epitope: hTg 26
Chemical type: Peptide from protein
Sequence: PPARALKRSLWVEVDLLIGS
Position: 2491-2510
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive
Host:  20 to 75

Epitope: hTg 27
Chemical type: Peptide from protein
Sequence: EVDLLIGSSQDDGLINRAKA
Position: 2503-2522
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 28
Chemical type: Peptide from protein
Sequence: GLINRAKAVKQFEESRGRTS
Position: 2515-2534
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 29
Chemical type: Peptide from protein
Sequence: EESRGRTSSKTAFYQALQNS
Position: 2527-2546
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 30
Chemical type: Peptide from protein
Sequence: FYQALQNSLGGEDSDARVEA
Position: 2539-2558
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 31
Chemical type: Peptide from protein
Sequence: DSDARVEAAATWYYSLEHST
Position: 2551-2570
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 32
Chemical type: Peptide from protein
Sequence: YYSLEHSTDDYASFSRALEN
Position: 2563-2582
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 33
Chemical type: Peptide from protein
Sequence: SFSRALENATRDYFIICPII
Position: 2575-2594
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 34
Chemical type: Peptide from protein
Sequence: YFIICPIIDMASAWAKRARG
Position: 2587-2606
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 36
Chemical type: Peptide from protein
Sequence: YHAPENYGHGSLELLADVQF
Position: 2611-2630
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 37
Chemical type: Peptide from protein
Sequence: ELLADVQFALGLPFYPAYEG
Position: 2623-2642
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 38
Chemical type: Peptide from protein
Sequence: PFYPAYEGQFSLEEKSLSLK
Position: 2635-2654
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 39
Chemical type: Peptide from protein
Sequence: EEKSLSLKIMQYFSHFIRSG
Position: 2647-2666
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Negative

Epitope: hTg 40
Chemical type: Peptide from protein
Sequence: FSHFIRSGNPNYPYEFSRKV
Position: 2659-2678
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 41
Chemical type: Peptide from protein
Sequence: PYEFSRKVPTFATPWPDFVP
Position: 2671-2690
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive
Host:  20 to 75

Epitope: hTg 41
Chemical type: Peptide from protein
Sequence: PYEFSRKVPTFATPWPDFVP
Position: 2671-2690
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Negative
Host:  17 to 84

Epitope: hTg 41
Chemical type: Peptide from protein
Sequence: PYEFSRKVPTFATPWPDFVP
Position: 2671-2690
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive
Host:  15-78 years

Epitope: hTg 41
Chemical type: Peptide from protein
Sequence: PYEFSRKVPTFATPWPDFVP
Position: 2671-2690
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive
Host:  17 to 84

Epitope: hTg 42
Chemical type: Peptide from protein
Sequence: TPWPDFVPRAGGENYKEFSE
Position: 2683-2702
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 43
Chemical type: Peptide from protein
Sequence: ENYKEFSELLPNRQGLKKAD
Position: 2695-2714
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 44
Chemical type: Peptide from protein
Sequence: RQGLKKADCSFWSKYISSLK
Position: 2707-2726
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 45
Chemical type: Peptide from protein
Sequence: SKYISSLKTSADGAKGGQSA
Position: 2719-2738
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Negative

Epitope: hTg 46
Chemical type: Peptide from protein
Sequence: GAKGGQSAESEEEELTAGSG
Position: 2731-2750
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Negative

Epitope: hTg 47
Chemical type: Peptide from protein
Sequence: EELTAGSGLREDLLSLQEPG
Position: 2743-2762
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 48
Chemical type: Peptide from protein
Sequence: LLSLQEPGSKTYSK
Position: 2755-2768
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive