Reference: Alexander Hellesen; Sigrid Aslaksen; Lars Breivik; Ellen Christine Røyrvik; Øyvind Bruserud; Kine Edvardsen; Karl Albert Brokstad; Anette Susanne Bøe Wolff; Eystein Sverre Husebye; Eirik Bratland. "21-Hydroxylase-Specific CD8+ T Cells in Autoimmune Addison's Disease Are Restricted by HLA-A2 and HLA-C7 Molecules." Frontiers in immunology (2021).

Epitope: 21OH 342-350
Chemical type: Peptide from protein
Sequence: LLNATIAEV
Position: 344-352
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21OH 342-350
Chemical type: Peptide from protein
Sequence: LLNATIAEV
Position: 344-352
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21OH 342-350
Chemical type: Peptide from protein
Sequence: LLNATIAEV
Position: 344-352
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 21OH 342-350
Chemical type: Peptide from protein
Sequence: LLNATIAEV
Position: 344-352
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 21OH 342-350
Chemical type: Peptide from protein
Sequence: LLNATIAEV
Position: 344-352
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21OH 342-350
Chemical type: Peptide from protein
Sequence: LLNATIAEV
Position: 344-352
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21OH 342-350
Chemical type: Peptide from protein
Sequence: LLNATIAEV
Position: 344-352
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 21OH 342-350
Chemical type: Peptide from protein
Sequence: LLNATIAEV
Position: 344-352
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 21 OH 430-437_Pep1
Chemical type: Peptide from protein
Sequence: GEPLARLEL
Position: 430-438
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 430-437_Pep1
Chemical type: Peptide from protein
Sequence: GEPLARLEL
Position: 430-438
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 430-437_Pep1
Chemical type: Peptide from protein
Sequence: GEPLARLEL
Position: 430-438
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative

Epitope: 21 OH 431-438_Pep2
Chemical type: Peptide from protein
Sequence: EPLARLELF
Position: 431-439
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 431-438_Pep2
Chemical type: Peptide from protein
Sequence: EPLARLELF
Position: 431-439
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 415.8

Epitope: 21 OH 432-439_Pep3
Chemical type: Peptide from protein
Sequence: PLARLELFV
Position: 432-440
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 432-439_Pep3
Chemical type: Peptide from protein
Sequence: PLARLELFV
Position: 432-440
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative

Epitope: 21 OH 433-440_Pep4
Chemical type: Peptide from protein
Sequence: LARLELFVV
Position: 433-441
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 433-440_Pep4
Chemical type: Peptide from protein
Sequence: LARLELFVV
Position: 433-441
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative

Epitope: 21 OH 434-441_Pep5
Chemical type: Peptide from protein
Sequence: ARLELFVVL
Position: 434-442
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 434-441_Pep5
Chemical type: Peptide from protein
Sequence: ARLELFVVL
Position: 434-442
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 434-441_Pep5
Chemical type: Peptide from protein
Sequence: ARLELFVVL
Position: 434-442
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 434-441_Pep5
Chemical type: Peptide from protein
Sequence: ARLELFVVL
Position: 434-442
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 434-441_Pep5
Chemical type: Peptide from protein
Sequence: ARLELFVVL
Position: 434-442
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 434-441_Pep5
Chemical type: Peptide from protein
Sequence: ARLELFVVL
Position: 434-442
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 434-441_Pep5
Chemical type: Peptide from protein
Sequence: ARLELFVVL
Position: 434-442
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 434-441_Pep5
Chemical type: Peptide from protein
Sequence: ARLELFVVL
Position: 434-442
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 434-441_Pep5
Chemical type: Peptide from protein
Sequence: ARLELFVVL
Position: 434-442
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative

Epitope: 21 OH 435-442_Pep6
Chemical type: Peptide from protein
Sequence: RLELFVVLT
Position: 435-443
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 435-442_Pep6
Chemical type: Peptide from protein
Sequence: RLELFVVLT
Position: 435-443
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 435-442_Pep6
Chemical type: Peptide from protein
Sequence: RLELFVVLT
Position: 435-443
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative

Epitope: 21 OH 436-443_Pep7
Chemical type: Peptide from protein
Sequence: LELFVVLTR
Position: 436-444
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 436-443_Pep7
Chemical type: Peptide from protein
Sequence: LELFVVLTR
Position: 436-444
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative

Epitope: 21 OH 437-444_Pep8
Chemical type: Peptide from protein
Sequence: ELFVVLTRL
Position: 437-445
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 437-444_Pep8
Chemical type: Peptide from protein
Sequence: ELFVVLTRL
Position: 437-445
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 437-444_Pep8
Chemical type: Peptide from protein
Sequence: ELFVVLTRL
Position: 437-445
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative

Epitope: 21 OH 438-445_Pep9
Chemical type: Peptide from protein
Sequence: LFVVLTRLL
Position: 438-446
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 438-445_Pep9
Chemical type: Peptide from protein
Sequence: LFVVLTRLL
Position: 438-446
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 439-446_Pep10
Chemical type: Peptide from protein
Sequence: FVVLTRLLQ
Position: 439-447
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 439-446_Pep10
Chemical type: Peptide from protein
Sequence: FVVLTRLLQ
Position: 439-447
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative

Epitope: 21 OH 430-447_Pep34
Chemical type: Peptide from protein
Sequence: GEPLARLELFVVLTRLLQ
Position: 430-447
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 430-447_Pep34
Chemical type: Peptide from protein
Sequence: GEPLARLELFVVLTRLLQ
Position: 430-447
Source molecule (GenBank): P08686.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 21 OH 430-437_P1
Chemical type: Peptide from protein
Sequence: GEPLARLE
Position: 430-437
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative

Epitope: 21 OH 432-439_P3
Chemical type: Peptide from protein
Sequence: PLARLELF
Position: 432-439
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative

Epitope: 21 OH 433-440_P4
Chemical type: Peptide from protein
Sequence: LARLELFV
Position: 433-440
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative

Epitope: 21 OH 434-441_P5
Chemical type: Peptide from protein
Sequence: ARLELFVV
Position: 434-441
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative

Epitope: 21 OH 435-442_P6
Chemical type: Peptide from protein
Sequence: RLELFVVL
Position: 435-442
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative

Epitope: 21 OH 436-443_P7
Chemical type: Peptide from protein
Sequence: LELFVVLT
Position: 436-443
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative

Epitope: 21 OH 437-444_P8
Chemical type: Peptide from protein
Sequence: ELFVVLTR
Position: 437-444
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative

Epitope: 21 OH 438-445_P9
Chemical type: Peptide from protein
Sequence: LFVVLTRL
Position: 438-445
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative

Epitope: 21 OH 440-447_P11
Chemical type: Peptide from protein
Sequence: VVLTRLLQ
Position: 440-447
Source molecule (GenBank): P08686.1
Assay category: MhcBinding
Result: Negative