Reference: Hualong Feng; Zuowei Wang; Ling Li; Yunjian Li; Maosheng Lu; Xixian Chen; Lin Hu; Yi Sun; Ruiping Du; Rongrong Qin; Xuanyi Chen; Liwei Jiang; Teng Zuo. "Discovery of Synergistic Broadly Neutralizing Antibodies Targeting Non-Dominant Epitopes on SARS-CoV-2 RBD and NTD." Vaccines (2025).

Epitope: Neutralizing Epitope on RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R357, D428, K462, F464, R466, I468
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: Neutralizing Epitope on RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R357, D428, K462, F464, R466, I468
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R357, D428, K462, F464, R466, I468
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R357, D428, K462, F464, R466, I468
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R357, D428, K462, F464, R466, I468
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R357, D428, K462, F464, R466, I468
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R357, D428, K462, F464, R466, I468
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R357, D428, K462, F464, R466, I468
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R357, D428, K462, F464, R466, I468
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R357, D428, K462, F464, R466, I468
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R357, D428, K462, F464, R466, I468
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R357, D428, K462, F464, R466, I468
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R357, D428, K462, F464, R466, I468
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab IMCAS74 on SARS-CoV2 Delta RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R353, K354, R355, N392, Y394, P424, D426, F427, T428, K460, P461, F462, E463, R464, I466, S512, F513, E514, L515, L516, H517
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on NTD
Chemical type: Discontinuous protein residues
Discontinuous residues: Q23, Y28, F65, P82, L84, P85, D88, K113, T236
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on NTD
Chemical type: Discontinuous protein residues
Discontinuous residues: Q23, Y28, F65, P82, L84, P85, D88, K113, T236
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: Neutralizing Epitope on NTD
Chemical type: Discontinuous protein residues
Discontinuous residues: Q23, Y28, F65, P82, L84, P85, D88, K113, T236
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on NTD
Chemical type: Discontinuous protein residues
Discontinuous residues: Q23, Y28, F65, P82, L84, P85, D88, K113, T236
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on NTD
Chemical type: Discontinuous protein residues
Discontinuous residues: Q23, Y28, F65, P82, L84, P85, D88, K113, T236
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: Neutralizing Epitope on NTD
Chemical type: Discontinuous protein residues
Discontinuous residues: Q23, Y28, F65, P82, L84, P85, D88, K113, T236
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: Neutralizing Epitope on NTD
Chemical type: Discontinuous protein residues
Discontinuous residues: Q23, Y28, F65, P82, L84, P85, D88, K113, T236
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: Neutralizing Epitope on NTD
Chemical type: Discontinuous protein residues
Discontinuous residues: Q23, Y28, F65, P82, L84, P85, D88, K113, T236
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: Neutralizing Epitope on NTD
Chemical type: Discontinuous protein residues
Discontinuous residues: Q23, Y28, F65, P82, L84, P85, D88, K113, T236
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on NTD
Chemical type: Discontinuous protein residues
Discontinuous residues: Q23, Y28, F65, P82, L84, P85, D88, K113, T236
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on NTD
Chemical type: Discontinuous protein residues
Discontinuous residues: Q23, Y28, F65, P82, L84, P85, D88, K113, T236
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on NTD
Chemical type: Discontinuous protein residues
Discontinuous residues: Q23, Y28, F65, P82, L84, P85, D88, K113, T236
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Neutralizing Epitope on NTD
Chemical type: Discontinuous protein residues
Discontinuous residues: Q23, Y28, F65, P82, L84, P85, D88, K113, T236
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive