Reference: Matthieu Besneux; Alexander Greenshields-Watson; Martin J Scurr; Bruce J MacLachlan; Adam Christian; Michael M Davies; Rachel Hargest; Simon Phillips; Andrew Godkin; Awen Gallimore. "The nature of the human T cell response to the cancer antigen 5T4 is determined by the balance of regulatory and inflammatory T cells of the same antigen-specificity: implications for vaccine design." Cancer immunology, immunotherapy : CII (2019).

Epitope: 5T4-Peptide 1
Chemical type: Peptide from protein
Sequence: MPGGCSRGPAAGDGRLRLAR
Position: 1-20
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 1
Chemical type: Peptide from protein
Sequence: MPGGCSRGPAAGDGRLRLAR
Position: 1-20
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 2
Chemical type: Peptide from protein
Sequence: AGDGRLRLARLALVLLGWVS
Position: 11-30
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 2
Chemical type: Peptide from protein
Sequence: AGDGRLRLARLALVLLGWVS
Position: 11-30
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 3
Chemical type: Peptide from protein
Sequence: LALVLLGWVSSSSPTSSASS
Position: 21-40
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 3
Chemical type: Peptide from protein
Sequence: LALVLLGWVSSSSPTSSASS
Position: 21-40
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 4
Chemical type: Peptide from protein
Sequence: SSSPTSSASSFSSSAPFLAS
Position: 31-50
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 4
Chemical type: Peptide from protein
Sequence: SSSPTSSASSFSSSAPFLAS
Position: 31-50
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 6
Chemical type: Peptide from protein
Sequence: AVSAQPPLPDQCPALCECSE
Position: 51-70
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 6
Chemical type: Peptide from protein
Sequence: AVSAQPPLPDQCPALCECSE
Position: 51-70
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 7
Chemical type: Peptide from protein
Sequence: QCPALCECSEAARTVKCVNR
Position: 61-80
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 7
Chemical type: Peptide from protein
Sequence: QCPALCECSEAARTVKCVNR
Position: 61-80
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 8
Chemical type: Peptide from protein
Sequence: AARTVKCVNRNLTEVPTDLP
Position: 71-90
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 8
Chemical type: Peptide from protein
Sequence: AARTVKCVNRNLTEVPTDLP
Position: 71-90
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 9
Chemical type: Peptide from protein
Sequence: NLTEVPTDLPAYVRNLFLTG
Position: 81-100
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 9
Chemical type: Peptide from protein
Sequence: NLTEVPTDLPAYVRNLFLTG
Position: 81-100
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 10
Chemical type: Peptide from protein
Sequence: AYVRNLFLTGNQLAVLPAGA
Position: 91-110
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 10
Chemical type: Peptide from protein
Sequence: AYVRNLFLTGNQLAVLPAGA
Position: 91-110
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 11
Chemical type: Peptide from protein
Sequence: NQLAVLPAGAFARRPPLAEL
Position: 101-120
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 11
Chemical type: Peptide from protein
Sequence: NQLAVLPAGAFARRPPLAEL
Position: 101-120
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 12
Chemical type: Peptide from protein
Sequence: FARRPPLAELAALNLSGSRL
Position: 111-130
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 12
Chemical type: Peptide from protein
Sequence: FARRPPLAELAALNLSGSRL
Position: 111-130
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 14
Chemical type: Peptide from protein
Sequence: DEVRAGAFEHLPSLRQLDLS
Position: 131-150
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 14
Chemical type: Peptide from protein
Sequence: DEVRAGAFEHLPSLRQLDLS
Position: 131-150
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 15
Chemical type: Peptide from protein
Sequence: LPSLRQLDLSHNPLADLSPF
Position: 141-160
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 15
Chemical type: Peptide from protein
Sequence: LPSLRQLDLSHNPLADLSPF
Position: 141-160
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 16
Chemical type: Peptide from protein
Sequence: HNPLADLSPFAFSGSNASVS
Position: 151-170
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 16
Chemical type: Peptide from protein
Sequence: HNPLADLSPFAFSGSNASVS
Position: 151-170
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 17
Chemical type: Peptide from protein
Sequence: AFSGSNASVSAPSPLVELIL
Position: 161-180
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 17
Chemical type: Peptide from protein
Sequence: AFSGSNASVSAPSPLVELIL
Position: 161-180
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 19
Chemical type: Peptide from protein
Sequence: NHIVPPEDERQNRSFEGMVV
Position: 181-200
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 19
Chemical type: Peptide from protein
Sequence: NHIVPPEDERQNRSFEGMVV
Position: 181-200
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 20
Chemical type: Peptide from protein
Sequence: QNRSFEGMVVAALLAGRALQ
Position: 191-210
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 20
Chemical type: Peptide from protein
Sequence: QNRSFEGMVVAALLAGRALQ
Position: 191-210
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 21
Chemical type: Peptide from protein
Sequence: AALLAGRALQGLRRLELASN
Position: 201-220
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 21
Chemical type: Peptide from protein
Sequence: AALLAGRALQGLRRLELASN
Position: 201-220
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 22
Chemical type: Peptide from protein
Sequence: GLRRLELASNHFLYLPRDVL
Position: 211-230
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 22
Chemical type: Peptide from protein
Sequence: GLRRLELASNHFLYLPRDVL
Position: 211-230
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 23
Chemical type: Peptide from protein
Sequence: HFLYLPRDVLAQLPSLRHLD
Position: 221-240
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 23
Chemical type: Peptide from protein
Sequence: HFLYLPRDVLAQLPSLRHLD
Position: 221-240
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 24
Chemical type: Peptide from protein
Sequence: AQLPSLRHLDLSNNSLVSLT
Position: 231-250
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 24
Chemical type: Peptide from protein
Sequence: AQLPSLRHLDLSNNSLVSLT
Position: 231-250
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 25
Chemical type: Peptide from protein
Sequence: LSNNSLVSLTYVSFRNLTHL
Position: 241-260
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 25
Chemical type: Peptide from protein
Sequence: LSNNSLVSLTYVSFRNLTHL
Position: 241-260
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 27
Chemical type: Peptide from protein
Sequence: ESLHLEDNALKVLHNGTLAE
Position: 261-280
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 27
Chemical type: Peptide from protein
Sequence: ESLHLEDNALKVLHNGTLAE
Position: 261-280
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 28
Chemical type: Peptide from protein
Sequence: KVLHNGTLAELQGLPHIRVF
Position: 271-290
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 28
Chemical type: Peptide from protein
Sequence: KVLHNGTLAELQGLPHIRVF
Position: 271-290
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 29
Chemical type: Peptide from protein
Sequence: LQGLPHIRVFLDNNPWVCDC
Position: 281-300
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 29
Chemical type: Peptide from protein
Sequence: LQGLPHIRVFLDNNPWVCDC
Position: 281-300
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 30
Chemical type: Peptide from protein
Sequence: LDNNPWVCDCHMADMVTWLK
Position: 291-310
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 30
Chemical type: Peptide from protein
Sequence: LDNNPWVCDCHMADMVTWLK
Position: 291-310
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 32
Chemical type: Peptide from protein
Sequence: ETEVVQGKDRLTCAYPEKMR
Position: 311-330
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 32
Chemical type: Peptide from protein
Sequence: ETEVVQGKDRLTCAYPEKMR
Position: 311-330
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 33
Chemical type: Peptide from protein
Sequence: LTCAYPEKMRNRVLLELNSA
Position: 321-340
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 33
Chemical type: Peptide from protein
Sequence: LTCAYPEKMRNRVLLELNSA
Position: 321-340
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 34
Chemical type: Peptide from protein
Sequence: NRVLLELNSADLDCDPILPP
Position: 331-350
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 34
Chemical type: Peptide from protein
Sequence: NRVLLELNSADLDCDPILPP
Position: 331-350
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 35
Chemical type: Peptide from protein
Sequence: DLDCDPILPPSLQTSYVFLG
Position: 341-360
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 35
Chemical type: Peptide from protein
Sequence: DLDCDPILPPSLQTSYVFLG
Position: 341-360
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 36
Chemical type: Peptide from protein
Sequence: SLQTSYVFLGIVLALIGAIF
Position: 351-370
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 36
Chemical type: Peptide from protein
Sequence: SLQTSYVFLGIVLALIGAIF
Position: 351-370
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 37
Chemical type: Peptide from protein
Sequence: IVLALIGAIFLLVLYLNRKG
Position: 361-380
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 37
Chemical type: Peptide from protein
Sequence: IVLALIGAIFLLVLYLNRKG
Position: 361-380
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 38
Chemical type: Peptide from protein
Sequence: LLVLYLNRKGIKKWMHNIRD
Position: 371-390
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 38
Chemical type: Peptide from protein
Sequence: LLVLYLNRKGIKKWMHNIRD
Position: 371-390
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 39
Chemical type: Peptide from protein
Sequence: IKKWMHNIRDACRDHMEGYH
Position: 381-400
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 39
Chemical type: Peptide from protein
Sequence: IKKWMHNIRDACRDHMEGYH
Position: 381-400
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 40
Chemical type: Peptide from protein
Sequence: ACRDHMEGYHYRYEINADPR
Position: 391-410
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 40
Chemical type: Peptide from protein
Sequence: ACRDHMEGYHYRYEINADPR
Position: 391-410
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 41
Chemical type: Peptide from protein
Sequence: YRYEINADPRLTNLSSNSDV
Position: 401-420
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: 5T4-Peptide 41
Chemical type: Peptide from protein
Sequence: YRYEINADPRLTNLSSNSDV
Position: 401-420
Source molecule (GenBank): Q13641.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated