Reference: V B Gibson; T Nikolic; V Q Pearce; J Demengeot; B O Roep; M Peakman. "Proinsulin multi-peptide immunotherapy induces antigen-specific regulatory T cells and limits autoimmunity in a humanized model." Clinical and experimental immunology (2015).

Epitope: Human C13-32
Chemical type: Peptide from protein
Sequence: GGGPGAGSLQPLALEGSLQK
Position: 69-88
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive-Low

Epitope: Human C13-32
Chemical type: Peptide from protein
Sequence: GGGPGAGSLQPLALEGSLQK
Position: 69-88
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human C13-32
Chemical type: Peptide from protein
Sequence: GGGPGAGSLQPLALEGSLQK
Position: 69-88
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human C19-A3
Chemical type: Peptide from protein
Sequence: GSLQPLALEGSLQKRGIV
Position: 75-92
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human C19-A3
Chemical type: Peptide from protein
Sequence: GSLQPLALEGSLQKRGIV
Position: 75-92
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive-Low

Epitope: Human C19-A3
Chemical type: Peptide from protein
Sequence: GSLQPLALEGSLQKRGIV
Position: 75-92
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human C19-A3
Chemical type: Peptide from protein
Sequence: GSLQPLALEGSLQKRGIV
Position: 75-92
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human C22-A5
Chemical type: Peptide from protein
Sequence: QPLALEGSLQKRGIVEQ
Position: 78-94
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human C22-A5
Chemical type: Peptide from protein
Sequence: QPLALEGSLQKRGIVEQ
Position: 78-94
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive-Low

Epitope: Human C22-A5
Chemical type: Peptide from protein
Sequence: QPLALEGSLQKRGIVEQ
Position: 78-94
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human C22-A5
Chemical type: Peptide from protein
Sequence: QPLALEGSLQKRGIVEQ
Position: 78-94
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Mouse C22-A5
Chemical type: Peptide from protein
Sequence: QTLALEVARQKRGIVDQ
Position: 76-92
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Mouse C22-A5
Chemical type: Peptide from protein
Sequence: QTLALEVARQKRGIVDQ
Position: 76-92
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Mouse C22-A5
Chemical type: Peptide from protein
Sequence: QTLALEVARQKRGIVDQ
Position: 76-92
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Mouse C19-A3
Chemical type: Peptide from protein
Sequence: GDLQTLALEVARQKRGIV
Position: 73-90
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo