Reference: Juan Feng; Xianchi Dong; Adam DeCosta; Yang Su; Fiona Angrisano; Katarzyna A Sala; Andrew M Blagborough; Chafen Lu; Timothy A Springer. "Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2." eLife (2021).

Epitope: Epitope of Fab 2/6.14 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: S541, S543, R565, I595, K597, D598, S599, N600, G601, K602, E603
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00322

Epitope: Epitope of Fab 2/6.14 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: S541, S543, R565, I595, K597, D598, S599, N600, G601, K602, E603
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive
Quantitative measurement: 303000.0

Epitope: Epitope of Fab 2/6.14 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: S541, S543, R565, I595, K597, D598, S599, N600, G601, K602, E603
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 505.0

Epitope: Epitope of Fab 2/6.14 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: S541, S543, R565, I595, K597, D598, S599, N600, G601, K602, E603
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 255.0

Epitope: Epitope of Fab 2/6.14 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: S541, S543, R565, I595, K597, D598, S599, N600, G601, K602, E603
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 484.0

Epitope: Epitope of Fab 2/6.14 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: S541, S543, R565, I595, K597, D598, S599, N600, G601, K602, E603
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive
Quantitative measurement: 10.2

Epitope: Epitope of Fab 2/6.14 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: S541, S543, R565, I595, K597, D598, S599, N600, G601, K602, E603
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 1243.0

Epitope: Epitope of Fab 2/6.14 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: S541, S543, R565, I595, K597, D598, S599, N600, G601, K602, E603
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 2/6.14 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: S541, S543, R565, I595, K597, D598, S599, N600, G601, K602, E603
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive
Quantitative measurement: 2.8

Epitope: Epitope of Fab 2/6.14 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: S541, S543, R565, I595, K597, D598, S599, N600, G601, K602, E603
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive-High
Quantitative measurement: 9.5

Epitope: Epitope of Fab 2/6.14 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: S541, S543, R565, I595, K597, D598, S599, N600, G601, K602, E603
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive-High
Quantitative measurement: 1.0

Epitope: Epitope of Fab 2/6.14 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: S541, S543, R565, I595, K597, D598, S599, N600, G601, K602, E603
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 2/6.14 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: S541, S543, R565, I595, K597, D598, S599, N600, G601, K602, E603
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 2/1.12 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T508, E522, V524, I526, H528, A562, V564, N573, Y574, A575, F576, Y577, I579
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive
Quantitative measurement: 85000.0

Epitope: Epitope of Fab 2/1.12 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T508, E522, V524, I526, H528, A562, V564, N573, Y574, A575, F576, Y577, I579
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive
Quantitative measurement: 5.9

Epitope: Epitope of Fab 2/1.12 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T508, E522, V524, I526, H528, A562, V564, N573, Y574, A575, F576, Y577, I579
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00050

Epitope: Epitope of Fab 2/1.12 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T508, E522, V524, I526, H528, A562, V564, N573, Y574, A575, F576, Y577, I579
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 2/1.12 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T508, E522, V524, I526, H528, A562, V564, N573, Y574, A575, F576, Y577, I579
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 86.0

Epitope: Epitope of Fab 2/1.12 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T508, E522, V524, I526, H528, A562, V564, N573, Y574, A575, F576, Y577, I579
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 260.0

Epitope: Epitope of Fab 2/1.12 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T508, E522, V524, I526, H528, A562, V564, N573, Y574, A575, F576, Y577, I579
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive
Quantitative measurement: 2.1

Epitope: Epitope of Fab 2/1.12 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T508, E522, V524, I526, H528, A562, V564, N573, Y574, A575, F576, Y577, I579
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive-High
Quantitative measurement: 0.87

Epitope: Epitope of Fab 2/1.12 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T508, E522, V524, I526, H528, A562, V564, N573, Y574, A575, F576, Y577, I579
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive-High
Quantitative measurement: 5.7

Epitope: Epitope of Fab 2/1.12 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T508, E522, V524, I526, H528, A562, V564, N573, Y574, A575, F576, Y577, I579
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 68.0

Epitope: Epitope of Fab 2/1.12 on Pb HAP2 D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T508, E522, V524, I526, H528, A562, V564, N573, Y574, A575, F576, Y577, I579
Source molecule (GenBank): Q4YCF6
Assay category: BCell
Result: Positive-High
Quantitative measurement: 20.0