Reference: Ronald T Toth; Siva Krishna Angalakurthi; Greta Van Slyke; David J Vance; John M Hickey; Sangeeta B Joshi; C Russell Middaugh; David B Volkin; David D Weis; Nicholas J Mantis. "High-Definition Mapping of Four Spatially Distinct Neutralizing Epitope Clusters on RiVax, a Candidate Ricin Toxin Subunit Vaccine." Clinical and vaccine immunology :  CVI. (2017).

Epitope: RiVax 94-107 (PB10 and R70 epitope)
Chemical type: Peptide from protein
Sequence: HPDNQEDAEAITHL
Position: 129-142
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive

Epitope: RiVax 94-107 (PB10 and R70 epitope)
Chemical type: Peptide from protein
Sequence: HPDNQEDAEAITHL
Position: 129-142
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Host: F 10-12 weeks

Epitope: RiVax 94-107 (PB10 and R70 epitope)
Chemical type: Peptide from protein
Sequence: HPDNQEDAEAITHL
Position: 129-142
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 720000.0

Epitope: RiVax 94-107 (PB10 and R70 epitope)
Chemical type: Peptide from protein
Sequence: HPDNQEDAEAITHL
Position: 129-142
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000139

Epitope: RiVax 94-107 (PB10 and R70 epitope)
Chemical type: Peptide from protein
Sequence: HPDNQEDAEAITHL
Position: 129-142
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0194

Epitope: RiVax 94-107 (PB10 and R70 epitope)
Chemical type: Peptide from protein
Sequence: HPDNQEDAEAITHL
Position: 129-142
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00124
Host: F 10-12 weeks

Epitope: RiVax 94-107 (PB10 and R70 epitope)
Chemical type: Peptide from protein
Sequence: HPDNQEDAEAITHL
Position: 129-142
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1010000.0
Host: F 10-12 weeks

Epitope: RiVax 94-107 (PB10 and R70 epitope)
Chemical type: Peptide from protein
Sequence: HPDNQEDAEAITHL
Position: 129-142
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00000125
Host: F 10-12 weeks

Epitope: Epitope of mAb WECB2 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: H129, P130, D131, N132, Q133, E134, D135, A136, E137, A138, I139, T140, H141, L142, F143, D145, V146, Q147, N148, R149, Y150, T151, F152, A153, F154, G155, G156, N157
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Host: F 8-10 weeks

Epitope: Epitope of mAb WECB2 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: H129, P130, D131, N132, Q133, E134, D135, A136, E137, A138, I139, T140, H141, L142, F143, D145, V146, Q147, N148, R149, Y150, T151, F152, A153, F154, G155, G156, N157
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0031
Host: F 8-10 weeks

Epitope: Epitope of mAb WECB2 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: H129, P130, D131, N132, Q133, E134, D135, A136, E137, A138, I139, T140, H141, L142, F143, D145, V146, Q147, N148, R149, Y150, T151, F152, A153, F154, G155, G156, N157
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1130000.0
Host: F 8-10 weeks

Epitope: Epitope of mAb WECB2 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: H129, P130, D131, N132, Q133, E134, D135, A136, E137, A138, I139, T140, H141, L142, F143, D145, V146, Q147, N148, R149, Y150, T151, F152, A153, F154, G155, G156, N157
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000035
Host: F 8-10 weeks

Epitope: Epitope of mAb SyH7 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: A49, G50, A51, T52, V53, Q54, S55, Y56, T57, N58, F59, I219, E220, G221, E222, M223, R224, T225, R226, I227, R228, Y229, N230, R231, R232, S233, A234, P235, D236, P237, S238, V239, I240, T241, L242
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Host: F 10-12 weeks

Epitope: Epitope of mAb SyH7 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: A49, G50, A51, T52, V53, Q54, S55, Y56, T57, N58, F59, I219, E220, G221, E222, M223, R224, T225, R226, I227, R228, Y229, N230, R231, R232, S233, A234, P235, D236, P237, S238, V239, I240, T241, L242
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0203
Host: F 10-12 weeks

Epitope: Epitope of mAb SyH7 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: A49, G50, A51, T52, V53, Q54, S55, Y56, T57, N58, F59, I219, E220, G221, E222, M223, R224, T225, R226, I227, R228, Y229, N230, R231, R232, S233, A234, P235, D236, P237, S238, V239, I240, T241, L242
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 415000.0
Host: F 10-12 weeks

Epitope: Epitope of mAb SyH7 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: A49, G50, A51, T52, V53, Q54, S55, Y56, T57, N58, F59, I219, E220, G221, E222, M223, R224, T225, R226, I227, R228, Y229, N230, R231, R232, S233, A234, P235, D236, P237, S238, V239, I240, T241, L242
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00000844
Host: F 10-12 weeks

Epitope: RiVax 184-204 (PA1 epitope)
Chemical type: Peptide from protein
Sequence: IEGEMRTRIRYNRRSAPDPSV
Position: 219-239
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Host: F 8-10 weeks

Epitope: RiVax 184-204 (PA1 epitope)
Chemical type: Peptide from protein
Sequence: IEGEMRTRIRYNRRSAPDPSV
Position: 219-239
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00000792
Host: F 8-10 weeks

Epitope: RiVax 184-204 (PA1 epitope)
Chemical type: Peptide from protein
Sequence: IEGEMRTRIRYNRRSAPDPSV
Position: 219-239
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00919
Host: F 8-10 weeks

Epitope: RiVax 184-204 (PA1 epitope)
Chemical type: Peptide from protein
Sequence: IEGEMRTRIRYNRRSAPDPSV
Position: 219-239
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 861000.0
Host: F 8-10 weeks

Epitope: Epitope of mAb TB12 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: V95, E96, L97, S98, N99, H100, A101, E102, L103, S104, S190, T191, G192, G193, T194, Q195, L196, P197, T198, L199
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00442
Host: F 8-10 weeks

Epitope: Epitope of mAb TB12 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: V95, E96, L97, S98, N99, H100, A101, E102, L103, S104, S190, T191, G192, G193, T194, Q195, L196, P197, T198, L199
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 614000.0
Host: F 8-10 weeks

Epitope: Epitope of mAb TB12 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: V95, E96, L97, S98, N99, H100, A101, E102, L103, S104, S190, T191, G192, G193, T194, Q195, L196, P197, T198, L199
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000271
Host: F 8-10 weeks

Epitope: Epitope of mAb TB12 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: V95, E96, L97, S98, N99, H100, A101, E102, L103, S104, S190, T191, G192, G193, T194, Q195, L196, P197, T198, L199
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Host: F 8-10 weeks

Epitope: Epitope of mAb PH12 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: L97, S98, N99, H100, A101, E102, L103, S104, Y189, S190, T191, G192, G193, T194, Q195, L196, P197, T198, L199
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 956000.0
Host: F 8-10 weeks

Epitope: Epitope of mAb PH12 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: L97, S98, N99, H100, A101, E102, L103, S104, Y189, S190, T191, G192, G193, T194, Q195, L196, P197, T198, L199
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000087
Host: F 8-10 weeks

Epitope: Epitope of mAb PH12 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: L97, S98, N99, H100, A101, E102, L103, S104, Y189, S190, T191, G192, G193, T194, Q195, L196, P197, T198, L199
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0091
Host: F 8-10 weeks

Epitope: Epitope of mAb PH12 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: L97, S98, N99, H100, A101, E102, L103, S104, Y189, S190, T191, G192, G193, T194, Q195, L196, P197, T198, L199
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Host: F 8-10 weeks

Epitope: Epitope of mAb IB2 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: G156, N157, Y158, D159, R160, L161, E162, Q163, L164, A165, G166, N167, L168, R169, E170, L242, E243, N244, S245, W246, G247, R248, L249, S250, T251, A252, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0493
Host: F 8-10 weeks

Epitope: Epitope of mAb IB2 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: G156, N157, Y158, D159, R160, L161, E162, Q163, L164, A165, G166, N167, L168, R169, E170, L242, E243, N244, S245, W246, G247, R248, L249, S250, T251, A252, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2710000.0
Host: F 8-10 weeks

Epitope: Epitope of mAb IB2 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: G156, N157, Y158, D159, R160, L161, E162, Q163, L164, A165, G166, N167, L168, R169, E170, L242, E243, N244, S245, W246, G247, R248, L249, S250, T251, A252, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000133
Host: F 8-10 weeks

Epitope: Epitope of mAb IB2 on RiVax
Chemical type: Discontinuous protein residues
Discontinuous residues: G156, N157, Y158, D159, R160, L161, E162, Q163, L164, A165, G166, N167, L168, R169, E170, L242, E243, N244, S245, W246, G247, R248, L249, S250, T251, A252, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Host: F 8-10 weeks

Epitope: RiVax 35-59 (GD12 epitope)
Chemical type: Peptide from protein
Sequence: GADVRHEIPVLPNRVGLPINQRFIL
Position: 70-94
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0552
Host: F 6-8 weeks

Epitope: RiVax 35-59 (GD12 epitope)
Chemical type: Peptide from protein
Sequence: GADVRHEIPVLPNRVGLPINQRFIL
Position: 70-94
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 222000.0
Host: F 6-8 weeks

Epitope: RiVax 35-59 (GD12 epitope)
Chemical type: Peptide from protein
Sequence: GADVRHEIPVLPNRVGLPINQRFIL
Position: 70-94
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000122
Host: F 6-8 weeks

Epitope: RiVax 35-59 (GD12 epitope)
Chemical type: Peptide from protein
Sequence: GADVRHEIPVLPNRVGLPINQRFIL
Position: 70-94
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: RiVax 251-255 (JD4 epitope)
Chemical type: Peptide from protein
Sequence: IIALMVYRC
Position: 286-294
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000247
Host: F 8-10 weeks

Epitope: RiVax 251-255 (JD4 epitope)
Chemical type: Peptide from protein
Sequence: IIALMVYRC
Position: 286-294
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0818
Host: F 8-10 weeks

Epitope: RiVax 251-255 (JD4 epitope)
Chemical type: Peptide from protein
Sequence: IIALMVYRC
Position: 286-294
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 30200.0
Host: F 8-10 weeks

Epitope: RiVax 251-255 (JD4 epitope)
Chemical type: Peptide from protein
Sequence: IIALMVYRC
Position: 286-294
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Host: F 8-10 weeks