Reference: Maria Serena Longhi; Munther J Hussain; Dimitrios P Bogdanos; Alberto Quaglia; Giorgina Mieli-Vergani; Yun Ma; Diego Vergani. "Cytochrome P450IID6-specific CD8 T cell immune responses mirror disease activity in autoimmune hepatitis type 2." Hepatology (Baltimore, Md.) (2007).

Epitope: CYP2D6 p1 176-185
Chemical type: Peptide from protein
Sequence: GLLDKAVSNV
Position: 176-185
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CYP2D6 p1 176-185
Chemical type: Peptide from protein
Sequence: GLLDKAVSNV
Position: 176-185
Source molecule (GenBank): P10635.2
Assay category: MhcBinding
Result: Positive

Epitope: CYP2D6 p2 204-213
Chemical type: Peptide from protein
Sequence: RLLDLAQEGL
Position: 204-213
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CYP2D6 p2 204-213
Chemical type: Peptide from protein
Sequence: RLLDLAQEGL
Position: 204-213
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CYP2D6 p2 204-213
Chemical type: Peptide from protein
Sequence: RLLDLAQEGL
Position: 204-213
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: CYP2D6 p2 204-213
Chemical type: Peptide from protein
Sequence: RLLDLAQEGL
Position: 204-213
Source molecule (GenBank): P10635.2
Assay category: MhcBinding
Result: Positive

Epitope: CYP2D6 p4 245-254
Chemical type: Peptide from protein
Sequence: KAFLTQLDEL
Position: 245-254
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: CYP2D6 p4 245-254
Chemical type: Peptide from protein
Sequence: KAFLTQLDEL
Position: 245-254
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CYP2D6 p4 245-254
Chemical type: Peptide from protein
Sequence: KAFLTQLDEL
Position: 245-254
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CYP2D6 p4 245-254
Chemical type: Peptide from protein
Sequence: KAFLTQLDEL
Position: 245-254
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Negative
MHC allele types: 235
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CYP2D6 p4 245-254
Chemical type: Peptide from protein
Sequence: KAFLTQLDEL
Position: 245-254
Source molecule (GenBank): P10635.2
Assay category: MhcBinding
Result: Negative

Epitope: CYP2D6 p6 177-186
Chemical type: Peptide from protein
Sequence: LLDKAVSNVI
Position: 177-186
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CYP2D6 p6 177-186
Chemical type: Peptide from protein
Sequence: LLDKAVSNVI
Position: 177-186
Source molecule (GenBank): P10635.2
Assay category: MhcBinding
Result: Negative

Epitope: CYP2D6 p7 306-314
Chemical type: Peptide from protein
Sequence: GMVTTSTTL
Position: 306-314
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CYP2D6 p7 306-314
Chemical type: Peptide from protein
Sequence: GMVTTSTTL
Position: 306-314
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: CYP2D6 p7 306-314
Chemical type: Peptide from protein
Sequence: GMVTTSTTL
Position: 306-314
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CYP2D6 p7 306-314
Chemical type: Peptide from protein
Sequence: GMVTTSTTL
Position: 306-314
Source molecule (GenBank): P10635.2
Assay category: MhcBinding
Result: Negative