Reference: Shasha Deng; Zhihao Xu; Meihua Wang; Jing Hu; Zhuan Liu; Fang Zhu; Peiyi Zheng; Arnaud John Kombe Kombe; Hongliang Zhang; Songquan Wu; Tengchuan Jin. "Structural insights into immune escape at killer T cell epitope by SARS-CoV-2 Spike Y453F variants." The Journal of biological chemistry (2024).

Epitope: Spike (448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Quantitative measurement: 8600.0

Epitope: Spike (448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Quantitative measurement: 10900.0

Epitope: Spike (448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Intermediate
Quantitative measurement: 57100.0

Epitope: Spike (448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Quantitative measurement: 3.2

Epitope: Spike (448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Quantitative measurement: 13500.0

Epitope: Spike (448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Intermediate

Epitope: Spike (448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive

Epitope: Spike (448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Intermediate

Epitope: Spike (448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Intermediate

Epitope: Spike (448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Intermediate

Epitope: Spike (448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Quantitative measurement: 19700.0

Epitope: Spike (448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 74600.0

Epitope: Spike (448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Intermediate
Quantitative measurement: 30600.0

Epitope: Spike (448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 116000.0

Epitope: Spike (448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 3.2

Epitope: Spike (448-456)
Chemical type: Peptide from protein
Sequence: NYNYLYRLF
Position: 448-456
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 49.44

Epitope: Spike (448-456) Y453F
Chemical type: Peptide from protein
Sequence: NYNYLFRLF
Position: 448-456
Source molecule (GenBank): ULE36913.1
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 116000.0

Epitope: Spike (448-456) Y453F
Chemical type: Peptide from protein
Sequence: NYNYLFRLF
Position: 448-456
Source molecule (GenBank): ULE36913.1
Assay category: TCell
Result: Positive-Intermediate

Epitope: Spike (448-456) Y453F
Chemical type: Peptide from protein
Sequence: NYNYLFRLF
Position: 448-456
Source molecule (GenBank): ULE36913.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 66.62

Epitope: Spike (448-456) Y453F
Chemical type: Peptide from protein
Sequence: NYNYLFRLF
Position: 448-456
Source molecule (GenBank): ULE36913.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.6

Epitope: Spike (448-456) L452R
Chemical type: Peptide from protein
Sequence: NYNYRYRLF
Position: 446-454
Source molecule (GenBank): UEO57867.1
Assay category: TCell
Result: Positive-Intermediate

Epitope: Spike (448-456) L452R
Chemical type: Peptide from protein
Sequence: NYNYRYRLF
Position: 446-454
Source molecule (GenBank): UEO57867.1
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 74600.0

Epitope: Spike (448-456) L452R
Chemical type: Peptide from protein
Sequence: NYNYRYRLF
Position: 446-454
Source molecule (GenBank): UEO57867.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 56.9

Epitope: Spike (448-456) N450K
Chemical type: Peptide from protein
Sequence: NYKYLYRLF
Position: 448-456
Source molecule (GenBank): URN55686.1
Assay category: TCell
Result: Positive-Intermediate

Epitope: Spike (448-456) N450K
Chemical type: Peptide from protein
Sequence: NYKYLYRLF
Position: 448-456
Source molecule (GenBank): URN55686.1
Assay category: TCell
Result: Positive
Quantitative measurement: 10900.0

Epitope: Spike (448-456) N450K
Chemical type: Peptide from protein
Sequence: NYKYLYRLF
Position: 448-456
Source molecule (GenBank): URN55686.1
Assay category: TCell
Result: Positive
Quantitative measurement: 19700.0

Epitope: Spike (448-456) L452Q
Chemical type: Peptide from protein
Sequence: NYNYQYRLF
Position: 445-453
Source molecule (GenBank): UUT98887.1
Assay category: TCell
Result: Positive-Intermediate

Epitope: Spike (448-456) L452Q
Chemical type: Peptide from protein
Sequence: NYNYQYRLF
Position: 445-453
Source molecule (GenBank): UUT98887.1
Assay category: TCell
Result: Positive-Intermediate
Quantitative measurement: 57100.0

Epitope: Spike (448-456) L452Q
Chemical type: Peptide from protein
Sequence: NYNYQYRLF
Position: 445-453
Source molecule (GenBank): UUT98887.1
Assay category: TCell
Result: Positive-Intermediate
Quantitative measurement: 30600.0