Reference: Jared Feldman; Ana Sofia Ferreira Ramos; Mya Vu; Daniel P Maurer; Victoria C Rosado; Daniel Lingwood; Goran Bajic; Aaron G Schmidt. "Human naïve B cells recognize prepandemic influenza virus hemagglutinins." Science immunology (2025).

Epitope: Epitope of Fab HD16_D04 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: N54, L57, D59, D61, G62, V63, K64, P65, I67, R69, D84, F86, I87, N88, P90, E91, S93, K98, H126, I280, Y287, N289, C290, N291, T292, K293, T296, I301, G316
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of Fab HD16_D04 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: N54, L57, D59, D61, G62, V63, K64, P65, I67, R69, D84, F86, I87, N88, P90, E91, S93, K98, H126, I280, Y287, N289, C290, N291, T292, K293, T296, I301, G316
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D04 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: N54, L57, D59, D61, G62, V63, K64, P65, I67, R69, D84, F86, I87, N88, P90, E91, S93, K98, H126, I280, Y287, N289, C290, N291, T292, K293, T296, I301, G316
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D04 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: N54, L57, D59, D61, G62, V63, K64, P65, I67, R69, D84, F86, I87, N88, P90, E91, S93, K98, H126, I280, Y287, N289, C290, N291, T292, K293, T296, I301, G316
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D04 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: N54, L57, D59, D61, G62, V63, K64, P65, I67, R69, D84, F86, I87, N88, P90, E91, S93, K98, H126, I280, Y287, N289, C290, N291, T292, K293, T296, I301, G316
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D04 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: N54, L57, D59, D61, G62, V63, K64, P65, I67, R69, D84, F86, I87, N88, P90, E91, S93, K98, H126, I280, Y287, N289, C290, N291, T292, K293, T296, I301, G316
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D04 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: N54, L57, D59, D61, G62, V63, K64, P65, I67, R69, D84, F86, I87, N88, P90, E91, S93, K98, H126, I280, Y287, N289, C290, N291, T292, K293, T296, I301, G316
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D04 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: N54, L57, D59, D61, G62, V63, K64, P65, I67, R69, D84, F86, I87, N88, P90, E91, S93, K98, H126, I280, Y287, N289, C290, N291, T292, K293, T296, I301, G316
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D04 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: N54, L57, D59, D61, G62, V63, K64, P65, I67, R69, D84, F86, I87, N88, P90, E91, S93, K98, H126, I280, Y287, N289, C290, N291, T292, K293, T296, I301, G316
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D04 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: N54, L57, D59, D61, G62, V63, K64, P65, I67, R69, D84, F86, I87, N88, P90, E91, S93, K98, H126, I280, Y287, N289, C290, N291, T292, K293, T296, I301, G316
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D04 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: N54, L57, D59, D61, G62, V63, K64, P65, I67, R69, D84, F86, I87, N88, P90, E91, S93, K98, H126, I280, Y287, N289, C290, N291, T292, K293, T296, I301, G316
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD15_1F06 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: E142, V147, I167, K168, S171, K205, R232, Q238, R241
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of Fab HD15_1F06 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: E142, V147, I167, K168, S171, K205, R232, Q238, R241
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD15_1F06 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: E142, V147, I167, K168, S171, K205, R232, Q238, R241
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD15_1F06 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: E142, V147, I167, K168, S171, K205, R232, Q238, R241
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD15_1F06 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: E142, V147, I167, K168, S171, K205, R232, Q238, R241
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D07 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: F86, K275, M281, E286, I310
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D07 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: F86, K275, M281, E286, I310
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D07 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: F86, K275, M281, E286, I310
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D07 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: F86, K275, M281, E286, I310
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Fab HD16_D07 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: F86, K275, M281, E286, I310
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D07 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: F86, K275, M281, E286, I310
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D07 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: F86, K275, M281, E286, I310
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D07 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: F86, K275, M281, E286, I310
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab HD16_D07 on H5 VN04 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: F86, K275, M281, E286, I310
Source molecule (GenBank): Q6DQ33.1
Assay category: BCell
Result: Positive