Reference: Ivana Durinovic-Belló; Bernhard O Boehm; Anette-G Ziegler. "Predominantly recognized proinsulin T helper cell epitopes in individuals with and without islet cell autoimmunity." Journal of autoimmunity (2002).

Epitope: B1-17
Chemical type: Peptide from protein
Sequence: FVNQHLCGSHLVEALYL
Position: 25-41
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 341
Host:  3-34 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B1-17
Chemical type: Peptide from protein
Sequence: FVNQHLCGSHLVEALYL
Position: 25-41
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  1-32 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B1-17
Chemical type: Peptide from protein
Sequence: FVNQHLCGSHLVEALYL
Position: 25-41
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 341 340 318 316
Host:  2-25 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B11–27
Chemical type: Peptide from protein
Sequence: LVEALYLVCGERGFFYT
Position: 35-51
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 341 318
Host:  2-25 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B11–27
Chemical type: Peptide from protein
Sequence: LVEALYLVCGERGFFYT
Position: 35-51
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Negative
Host:  1-32 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B11–27
Chemical type: Peptide from protein
Sequence: LVEALYLVCGERGFFYT
Position: 35-51
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 63 318
Host:  3-34 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B20–C4
Chemical type: Peptide from protein
Sequence: GERGFFYTPKTRREAED
Position: 44-60
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 341
Host:  3-34 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B20–C4
Chemical type: Peptide from protein
Sequence: GERGFFYTPKTRREAED
Position: 44-60
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 63 318
Host:  2-25 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B20–C4
Chemical type: Peptide from protein
Sequence: GERGFFYTPKTRREAED
Position: 44-60
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Negative
Host:  1-32 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B30–C14
Chemical type: Peptide from protein
Sequence: TRREAEDLQVGQVELGG
Position: 54-70
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Negative
Host:  1-32 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B30–C14
Chemical type: Peptide from protein
Sequence: TRREAEDLQVGQVELGG
Position: 54-70
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 341 340 318 316
Host:  2-25 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B30–C14
Chemical type: Peptide from protein
Sequence: TRREAEDLQVGQVELGG
Position: 54-70
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 63 318
Host:  3-34 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C18–A1
Chemical type: Peptide from protein
Sequence: AGSLQPLALEGSLQKRG
Position: 74-90
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 341
Host:  2-25 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C18–A1
Chemical type: Peptide from protein
Sequence: AGSLQPLALEGSLQKRG
Position: 74-90
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 63 318
Host:  3-34 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C18–A1
Chemical type: Peptide from protein
Sequence: AGSLQPLALEGSLQKRG
Position: 74-90
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  1-32 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C28–A11
Chemical type: Peptide from protein
Sequence: GSLQKRGIVEQCCTSIC
Position: 84-100
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 63 318
Host:  3-34 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C28–A11
Chemical type: Peptide from protein
Sequence: GSLQKRGIVEQCCTSIC
Position: 84-100
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Negative
Host:  1-32 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C28–A11
Chemical type: Peptide from protein
Sequence: GSLQKRGIVEQCCTSIC
Position: 84-100
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 63 318
Host:  2-25 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A6-21
Chemical type: Peptide from protein
Sequence: CCTSICSLYQLENYCN
Position: 95-110
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 341 318
Host:  3-34 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A6-21
Chemical type: Peptide from protein
Sequence: CCTSICSLYQLENYCN
Position: 95-110
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 341 318
Host:  2-25 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A6-21
Chemical type: Peptide from protein
Sequence: CCTSICSLYQLENYCN
Position: 95-110
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Negative
Host:  1-32 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo