Reference: Lars Guelen; Thierry O Fischmann; Jerelyn Wong; Smita Mauze; Marco Guadagnoli; Nikolina Bąbała; Jozef Wagenaars; Veronica Juan; David Rosen; Winnie Prosise; Maurice Habraken; Imke Lodewijks; Danling Gu; Judith Stammen-Vogelzangs; Ying Yu; Jeanne Baker; David Lutje Hulsik; Lilian Driessen-Engels; Dan Malashock; Joost Kreijtz; Astrid Bertens; Evert de Vries; Astrid Bovens; Arne Bramer; Yiwei Zhang; Richard Wnek; Sean Troth; Elliot Chartash; Konstantin Dobrenkov; Svetlana Sadekova; Andrea van Elsas; Jason K Cheung; Laurence Fayadat-Dilman; Jannie Borst; Amy M Beebe; Hans Van Eenennaam. "Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy." Journal for immunotherapy of cancer (2022).

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive-Intermediate
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Quantitative measurement: 1.93
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.32
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.054
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.3
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.22
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.17
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0011
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Quantitative measurement: 4.3
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Quantitative measurement: 230000.0
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.072
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Quantitative measurement: 220000.0
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of  MK-5890 Fab on CD27
Chemical type: Discontinuous protein residues
Discontinuous residues: P28, E29, H31, K37, L38, D54, Q55, H56, R57, K58
Source molecule (GenBank): P26842.2
Assay category: BCell
Result: Positive
Quantitative measurement: 5.1
Host: F