Reference: Edward F Rosloniec; Karen B Whittington; Xiaowen He; John M Stuart; Andrew H Kang. "Collagen-induced arthritis mediated by HLA-DR1 (*0101) and HLA-DR4 (*0401)." The American journal of the medical sciences (2004).

Epitope: hCII(244-258)
Chemical type: Peptide from protein
Sequence: GATGPLGPKGQTGED
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(244-258)
Chemical type: Peptide from protein
Sequence: GATGPLGPKGQTGED
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(244-258)
Chemical type: Peptide from protein
Sequence: GATGPLGPKGQTGED
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(247–261)
Chemical type: Peptide from protein
Sequence: GPLGPKGQTGEDGIA
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(247–261)
Chemical type: Peptide from protein
Sequence: GPLGPKGQTGEDGIA
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(247–261)
Chemical type: Peptide from protein
Sequence: GPLGPKGQTGEDGIA
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(250–264)
Chemical type: Peptide from protein
Sequence: GPKGQTGEDGIAGFK
Assay category: TCell
Result: Positive-Low
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(250–264)
Chemical type: Peptide from protein
Sequence: GPKGQTGEDGIAGFK
Assay category: TCell
Result: Positive-Low
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(250–264)
Chemical type: Peptide from protein
Sequence: GPKGQTGEDGIAGFK
Assay category: TCell
Result: Positive-Low
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(253–267)
Chemical type: Peptide from protein
Sequence: GQTGEDGIAGFKGEQ
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(253–267)
Chemical type: Peptide from protein
Sequence: GQTGEDGIAGFKGEQ
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(253–267)
Chemical type: Peptide from protein
Sequence: GQTGEDGIAGFKGEQ
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(256–270)
Chemical type: Peptide from protein
Sequence: GEDGIAGFKGEQGPK
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(256–270)
Chemical type: Peptide from protein
Sequence: GEDGIAGFKGEQGPK
Assay category: TCell
Result: Positive-High
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(256–270)
Chemical type: Peptide from protein
Sequence: GEDGIAGFKGEQGPK
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(259–273)
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGED
Assay category: TCell
Result: Positive-High
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(259–273)
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGED
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(259–273)
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGED
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(259–273)
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGED
Assay category: MhcBinding
Result: Positive

Epitope: hCII(259–273)
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGED
Assay category: MhcBinding
Result: Positive

Epitope: hCII(262–276)
Chemical type: Peptide from protein
Sequence: GFKGEQGPKGEDGPA
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(262–276)
Chemical type: Peptide from protein
Sequence: GFKGEQGPKGEDGPA
Assay category: TCell
Result: Positive-High
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(262–276)
Chemical type: Peptide from protein
Sequence: GFKGEQGPKGEDGPA
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(268–282)
Chemical type: Peptide from protein
Sequence: GPKGEDGPAGPQGAD
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(268–282)
Chemical type: Peptide from protein
Sequence: GPKGEDGPAGPQGAD
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(268–282)
Chemical type: Peptide from protein
Sequence: GPKGEDGPAGPQGAD
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(271–285)
Chemical type: Peptide from protein
Sequence: GEDGPAGPQGADGPA
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(271–285)
Chemical type: Peptide from protein
Sequence: GEDGPAGPQGADGPA
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(271–285)
Chemical type: Peptide from protein
Sequence: GEDGPAGPQGADGPA
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: hCII(263-270)
Chemical type: Peptide from protein
Sequence: FKGEQGPK
Position: 463-470
Source molecule (GenBank): AAC41772.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: hCII(263-270)
Chemical type: Peptide from protein
Sequence: FKGEQGPK
Position: 463-470
Source molecule (GenBank): AAC41772.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: G259A
Chemical type: Peptide, no natural source
Sequence: AIAGFKGEQGPKGEP
Assay category: MhcBinding
Result: Positive

Epitope: G259A
Chemical type: Peptide, no natural source
Sequence: AIAGFKGEQGPKGEP
Assay category: MhcBinding
Result: Positive

Epitope: G262A
Chemical type: Peptide, no natural source
Sequence: GIAAFKGEQGPKGEP
Assay category: MhcBinding
Result: Positive-High

Epitope: G262A
Chemical type: Peptide, no natural source
Sequence: GIAAFKGEQGPKGEP
Assay category: MhcBinding
Result: Positive-High

Epitope: F263A
Chemical type: Peptide, no natural source
Sequence: GIAGAKGEQGPKGEP
Assay category: MhcBinding
Result: Negative

Epitope: F263A
Chemical type: Peptide, no natural source
Sequence: GIAGAKGEQGPKGEP
Assay category: MhcBinding
Result: Negative

Epitope: E266A
Chemical type: Peptide, no natural source
Sequence: GIAGFKGAQGPKGEP
Assay category: MhcBinding
Result: Positive-High

Epitope: E266A
Chemical type: Peptide, no natural source
Sequence: GIAGFKGAQGPKGEP
Assay category: MhcBinding
Result: Positive-High

Epitope: Q267A
Chemical type: Peptide, no natural source
Sequence: GIAGFKGEAGPKGEP
Assay category: MhcBinding
Result: Positive

Epitope: Q267A
Chemical type: Peptide, no natural source
Sequence: GIAGFKGEAGPKGEP
Assay category: MhcBinding
Result: Positive

Epitope: G268A
Chemical type: Peptide, no natural source
Sequence: GIAGFKGEQAPKGEP
Assay category: MhcBinding
Result: Positive-High

Epitope: G268A
Chemical type: Peptide, no natural source
Sequence: GIAGFKGEQAPKGEP
Assay category: MhcBinding
Result: Positive-High

Epitope: P269A
Chemical type: Peptide, no natural source
Sequence: GIAGFKGEQGAKGEP
Assay category: MhcBinding
Result: Positive-High

Epitope: P269A
Chemical type: Peptide, no natural source
Sequence: GIAGFKGEQGAKGEP
Assay category: MhcBinding
Result: Positive-High

Epitope: K270A
Chemical type: Peptide, no natural source
Sequence: GIAGFKGEQGPAGEP
Assay category: MhcBinding
Result: Positive

Epitope: K270A
Chemical type: Peptide, no natural source
Sequence: GIAGFKGEQGPAGEP
Assay category: MhcBinding
Result: Positive

Epitope: G271A
Chemical type: Peptide, no natural source
Sequence: GIAGFKGEQGPKAEP
Assay category: MhcBinding
Result: Positive-High

Epitope: G271A
Chemical type: Peptide, no natural source
Sequence: GIAGFKGEQGPKAEP
Assay category: MhcBinding
Result: Positive-High

Epitope: E272A
Chemical type: Peptide, no natural source
Sequence: GIAGFKGEQGPKGAP
Assay category: MhcBinding
Result: Positive-High

Epitope: E272A
Chemical type: Peptide, no natural source
Sequence: GIAGFKGEQGPKGAP
Assay category: MhcBinding
Result: Positive-High