Reference: Keigo Yato; Taishi Onodera; Mami Matsuda; Saya Moriyama; Akira Fujimoto; Koichi Watashi; Hideki Aizaki; Tomohisa Tanaka; Kohji Moriishi; Hironori Nishitsuji; Kunitada Shimotohno; Koji Tamura; Yoshimasa Takahashi; Takaji Wakita; Masamichi Muramatsu; Takanobu Kato; Ryosuke Suzuki. "Identification of Two Critical Neutralizing Epitopes in the Receptor Binding Domain of Hepatitis B Virus preS1." Journal of virology (2021).

Epitope: preS1/2-47
Chemical type: Peptide from protein
Sequence: GTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNPNKDHWPEANQV
Position: 13-58
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: preS1/2-47
Chemical type: Peptide from protein
Sequence: GTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNPNKDHWPEANQV
Position: 13-58
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive-Intermediate
Host: F 9 weeks

Epitope: preS1/2-47
Chemical type: Peptide from protein
Sequence: GTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNPNKDHWPEANQV
Position: 13-58
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: preS1/2-47
Chemical type: Peptide from protein
Sequence: GTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNPNKDHWPEANQV
Position: 13-58
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: preS1/2-47
Chemical type: Peptide from protein
Sequence: GTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNPNKDHWPEANQV
Position: 13-58
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: preS1/2-47
Chemical type: Peptide from protein
Sequence: GTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNPNKDHWPEANQV
Position: 13-58
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: preS1/2-47
Chemical type: Peptide from protein
Sequence: GTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNPNKDHWPEANQV
Position: 13-58
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: preS1/2-47
Chemical type: Peptide from protein
Sequence: GTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNPNKDHWPEANQV
Position: 13-58
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive-Low
Host: F 9 weeks

Epitope: preS1/2-47
Chemical type: Peptide from protein
Sequence: GTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNPNKDHWPEANQV
Position: 13-58
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-L03/7/13 epitope
Chemical type: Peptide from protein
Sequence: PNKDHW
Position: 47-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00000010
Host: F 9 weeks

Epitope: BP-L03/7/13 epitope
Chemical type: Peptide from protein
Sequence: PNKDHW
Position: 47-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: F 9 weeks

Epitope: BP-L03/7/13 epitope
Chemical type: Peptide from protein
Sequence: PNKDHW
Position: 47-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 136000.0
Host: F 9 weeks

Epitope: BP-L03/7/13 epitope
Chemical type: Peptide from protein
Sequence: PNKDHW
Position: 47-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00000010
Host: F 9 weeks

Epitope: BP-L03/7/13 epitope
Chemical type: Peptide from protein
Sequence: PNKDHW
Position: 47-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: F 9 weeks

Epitope: BP-L03/7/13 epitope
Chemical type: Peptide from protein
Sequence: PNKDHW
Position: 47-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 366000.0
Host: F 9 weeks

Epitope: BP-L03/7/13 epitope
Chemical type: Peptide from protein
Sequence: PNKDHW
Position: 47-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-L03/7/13 epitope
Chemical type: Peptide from protein
Sequence: PNKDHW
Position: 47-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 160000.0
Host: F 9 weeks

Epitope: BP-L03/7/13 epitope
Chemical type: Peptide from protein
Sequence: PNKDHW
Position: 47-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 143000.0
Host: F 9 weeks

Epitope: BP-L03/7/13 epitope
Chemical type: Peptide from protein
Sequence: PNKDHW
Position: 47-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive-High
Host: F 9 weeks

Epitope: BP-L03/7/13 epitope
Chemical type: Peptide from protein
Sequence: PNKDHW
Position: 47-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00000010
Host: F 9 weeks

Epitope: BP-L03/7/13 epitope
Chemical type: Peptide from protein
Sequence: PNKDHW
Position: 47-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-L03/7/13 epitope
Chemical type: Peptide from protein
Sequence: PNKDHW
Position: 47-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: F 9 weeks

Epitope: BP-L10 epitope
Chemical type: Peptide from protein
Sequence: SNNPDWDFN
Position: 38-46
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-L10 epitope
Chemical type: Peptide from protein
Sequence: SNNPDWDFN
Position: 38-46
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-L10 epitope
Chemical type: Peptide from protein
Sequence: SNNPDWDFN
Position: 38-46
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.6
Host: F 9 weeks

Epitope: BP-L10 epitope
Chemical type: Peptide from protein
Sequence: SNNPDWDFN
Position: 38-46
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 750000.0
Host: F 9 weeks

Epitope: BP-L10 epitope
Chemical type: Peptide from protein
Sequence: SNNPDWDFN
Position: 38-46
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0012
Host: F 9 weeks

Epitope: BP-L16 epitope
Chemical type: Peptide from protein
Sequence: SNNPDWDF
Position: 38-45
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-L16 epitope
Chemical type: Peptide from protein
Sequence: SNNPDWDF
Position: 38-45
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-L16 epitope
Chemical type: Peptide from protein
Sequence: SNNPDWDF
Position: 38-45
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.5
Host: F 9 weeks

Epitope: BP-L16 epitope
Chemical type: Peptide from protein
Sequence: SNNPDWDF
Position: 38-45
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 530000.0
Host: F 9 weeks

Epitope: BP-L16 epitope
Chemical type: Peptide from protein
Sequence: SNNPDWDF
Position: 38-45
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00079
Host: F 9 weeks

Epitope: BP-L37 epitope
Chemical type: Peptide from protein
Sequence: FGANSNNPDW
Position: 34-43
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-L37 epitope
Chemical type: Peptide from protein
Sequence: FGANSNNPDW
Position: 34-43
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-L37 epitope
Chemical type: Peptide from protein
Sequence: FGANSNNPDW
Position: 34-43
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 270.0
Host: F 9 weeks

Epitope: BP-L37 epitope
Chemical type: Peptide from protein
Sequence: FGANSNNPDW
Position: 34-43
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 160000.0
Host: F 9 weeks

Epitope: BP-L37 epitope
Chemical type: Peptide from protein
Sequence: FGANSNNPDW
Position: 34-43
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.042
Host: F 9 weeks

Epitope: BP-L41 epitope
Chemical type: Peptide from protein
Sequence: PLGFFP
Position: 21-26
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-L41 epitope
Chemical type: Peptide from protein
Sequence: PLGFFP
Position: 21-26
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive-High
Host: F 9 weeks

Epitope: BP-L41 epitope
Chemical type: Peptide from protein
Sequence: PLGFFP
Position: 21-26
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive-High
Host: F 9 weeks

Epitope: BP-L41 epitope
Chemical type: Peptide from protein
Sequence: PLGFFP
Position: 21-26
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive-High
Host: F 9 weeks

Epitope: BP-L41 epitope
Chemical type: Peptide from protein
Sequence: PLGFFP
Position: 21-26
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-L41 epitope
Chemical type: Peptide from protein
Sequence: PLGFFP
Position: 21-26
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-L41 epitope
Chemical type: Peptide from protein
Sequence: PLGFFP
Position: 21-26
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 450000.0
Host: F 9 weeks

Epitope: BP-L41 epitope
Chemical type: Peptide from protein
Sequence: PLGFFP
Position: 21-26
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00099
Host: F 9 weeks

Epitope: BP-L41 epitope
Chemical type: Peptide from protein
Sequence: PLGFFP
Position: 21-26
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.2
Host: F 9 weeks

Epitope: BP-L41 epitope
Chemical type: Peptide from protein
Sequence: PLGFFP
Position: 21-26
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.8
Host: F 9 weeks

Epitope: BP-L41 epitope
Chemical type: Peptide from protein
Sequence: PLGFFP
Position: 21-26
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 12.0
Host: F 9 weeks

Epitope: BP-L41 epitope
Chemical type: Peptide from protein
Sequence: PLGFFP
Position: 21-26
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.4
Host: F 9 weeks

Epitope: BP-G54 epitope
Chemical type: Peptide from protein
Sequence: SNNPDWD
Position: 38-44
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive-Low
Host: F 9 weeks

Epitope: BP-G54 epitope
Chemical type: Peptide from protein
Sequence: SNNPDWD
Position: 38-44
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-G54 epitope
Chemical type: Peptide from protein
Sequence: SNNPDWD
Position: 38-44
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-G54 epitope
Chemical type: Peptide from protein
Sequence: SNNPDWD
Position: 38-44
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.8
Host: F 9 weeks

Epitope: BP-G54 epitope
Chemical type: Peptide from protein
Sequence: SNNPDWD
Position: 38-44
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 340000.0
Host: F 9 weeks

Epitope: BP-G54 epitope
Chemical type: Peptide from protein
Sequence: SNNPDWD
Position: 38-44
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00061
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive-High
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive-High
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive-High
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 240000.0
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00000010
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 400000.0
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00000010
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 150000.0
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2300.0
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: F 9 weeks

Epitope: BP-G82/88 epitope
Chemical type: Peptide from protein
Sequence: PNPLGF
Position: 19-24
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: F 9 weeks

Epitope: BP-G87 epitope
Chemical type: Peptide from protein
Sequence: NPNKDHW
Position: 46-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive-High
Host: F 9 weeks

Epitope: BP-G87 epitope
Chemical type: Peptide from protein
Sequence: NPNKDHW
Position: 46-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive-High
Host: F 9 weeks

Epitope: BP-G87 epitope
Chemical type: Peptide from protein
Sequence: NPNKDHW
Position: 46-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-G87 epitope
Chemical type: Peptide from protein
Sequence: NPNKDHW
Position: 46-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Host: F 9 weeks

Epitope: BP-G87 epitope
Chemical type: Peptide from protein
Sequence: NPNKDHW
Position: 46-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00000010
Host: F 9 weeks

Epitope: BP-G87 epitope
Chemical type: Peptide from protein
Sequence: NPNKDHW
Position: 46-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: F 9 weeks

Epitope: BP-G87 epitope
Chemical type: Peptide from protein
Sequence: NPNKDHW
Position: 46-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 73300.0
Host: F 9 weeks

Epitope: BP-G87 epitope
Chemical type: Peptide from protein
Sequence: NPNKDHW
Position: 46-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: F 9 weeks

Epitope: BP-G87 epitope
Chemical type: Peptide from protein
Sequence: NPNKDHW
Position: 46-52
Source molecule (GenBank): BAU25819.1
Assay category: BCell
Result: Positive
Quantitative measurement: 190.0
Host: F 9 weeks