Reference: Norman Woller; Engin Gürlevik; Bettina Fleischmann-Mundt; Anja Schumacher; Sarah Knocke; Arnold M Kloos; Michael Saborowski; Robert Geffers; Michael P Manns; Thomas C Wirth; Stefan Kubicka; Florian Kühnel. "Viral Infection of Tumors Overcomes Resistance to PD-1-immunotherapy by Broadening Neoantigenome-directed T-cell Responses." Molecular therapy : the journal of the American Society of Gene Therapy (2015).

Epitope: 25 Ndufs1
Chemical type: Peptide, no natural source
Sequence: AAVSNMVQKI
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 19 Gm15455
Chemical type: Peptide, no natural source
Sequence: ALEKNDMEQM
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 39 Chd2
Chemical type: Peptide, no natural source
Sequence: APLQNSLKEL
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 38 Hebp1
Chemical type: Peptide, no natural source
Sequence: AVFPNEDGSL
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 40 Arhgef10
Chemical type: Peptide, no natural source
Sequence: AWIENPEEA
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 41 Arhgef10
Chemical type: Peptide, no natural source
Sequence: AWIENPEEAI
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 07 Naip2
Chemical type: Peptide, no natural source
Sequence: CPLLNRFQL
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 08 Naip2
Chemical type: Peptide, no natural source
Sequence: CPLLNRFQLV
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 31 Rab13
Chemical type: Peptide, no natural source
Sequence: DKKNNKCLL
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 20 Gm15455
Chemical type: Peptide, no natural source
Sequence: DMASNEGSRI
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 26 Set
Chemical type: Peptide, no natural source
Sequence: FEDINSGYRI
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 18 Las2
Chemical type: Peptide, no natural source
Sequence: HTPDNAFVNL
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 33 Akap9
Chemical type: Peptide, no natural source
Sequence: IDRLNEQFM
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 06 Rpp40
Chemical type: Peptide, no natural source
Sequence: KELKNLVMDI
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 43 Uchl4
Chemical type: Peptide, no natural source
Sequence: KFLENYDAI
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 24 Gm15455
Chemical type: Peptide, no natural source
Sequence: KPKINEDWL
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 36 Paxip1
Chemical type: Peptide, no natural source
Sequence: KQSSFRKL
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 44 Gsta2
Chemical type: Peptide, no natural source
Sequence: LHHFNARGRM
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 34 Akap9
Chemical type: Peptide, no natural source
Sequence: LNEQFMKL
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 11 Acot10
Chemical type: Peptide, no natural source
Sequence: MHNHNHSTKM
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 22 Gm15455
Chemical type: Peptide, no natural source
Sequence: PSSENANDTI
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 35 Akap9
Chemical type: Peptide, no natural source
Sequence: RAQINGGEM
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 02 Grn
Chemical type: Peptide, no natural source
Sequence: RPAGYSCL
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 13 Muc4
Chemical type: Peptide, no natural source
Sequence: SAPITSTQI
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 30 Rab13
Chemical type: Peptide, no natural source
Sequence: SDKKNNKCL
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 32 Rab13
Chemical type: Peptide, no natural source
Sequence: SDKKNNKCLL
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 21 Gm15455
Chemical type: Peptide, no natural source
Sequence: SENANDTII
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 23 Gm15455
Chemical type: Peptide, no natural source
Sequence: SENANDTIIL
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 29 Nes
Chemical type: Peptide, no natural source
Sequence: SIEENLGTV
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 12 Zhx2
Chemical type: Peptide, no natural source
Sequence: SMGENPSKKL
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 04 Sp4
Chemical type: Peptide, no natural source
Sequence: SQPSPLALL
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 10 Acot10
Chemical type: Peptide, no natural source
Sequence: SWVGNTSMEV
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 14 H2-Q2
Chemical type: Peptide, no natural source
Sequence: TWQLNGEEL
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 09 Rad1
Chemical type: Peptide, no natural source
Sequence: YMIRNEDGRI
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 28 Prcc
Chemical type: Peptide, no natural source
Sequence: AAPMPEPTL
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 37 Ppat
Chemical type: Peptide, no natural source
Sequence: DPYGNRPLCM
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 16 Cep192
Chemical type: Peptide, no natural source
Sequence: FQIINNSVTL
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 27 Arhgef11
Chemical type: Peptide, no natural source
Sequence: LARLFPNL
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 15 Cep192
Chemical type: Peptide, no natural source
Sequence: QIINNSVTL
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 17 Cep192
Chemical type: Peptide, no natural source
Sequence: QIINNSVTLL
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 05 Lyst
Chemical type: Peptide, no natural source
Sequence: SEGFNVSLWF
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 45 WT H2-Q2
Chemical type: Peptide from protein
Sequence: TWQLNGEDL
Position: 237-245
Source molecule (GenBank): P01902.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 46 WT Ndufs1
Chemical type: Peptide from protein
Sequence: VAVSNMVQKI
Position: 491-500
Source molecule (GenBank): Q91VD9.2
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 47 WT Rab13
Chemical type: Peptide from protein
Sequence: SDKKKNKCL
Position: 192-200
Source molecule (GenBank): Q9DD03.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 48 WT Ppat
Chemical type: Peptide from protein
Sequence: DPYGNRPLCI
Position: 199-208
Source molecule (GenBank): Q8CIH9
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 49 WT  Gsta2
Chemical type: Peptide from protein
Sequence: LHYFNARGRM
Position: 7-16
Source molecule (GenBank): P10648.3
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 50 WT Chd2
Chemical type: Peptide from protein
Sequence: TPLQNSLKEL
Position: 647-656
Source molecule (GenBank): O14647.2
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 51 WT Arhgef10
Chemical type: Peptide from protein
Sequence: AWMENPEEAI
Position: 205-214
Source molecule (GenBank): Q8C033.2
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo