Reference: Leo Swadling; John Halliday; Christabel Kelly; Anthony Brown; Stefania Capone; M Azim Ansari; David Bonsall; Rachel Richardson; Felicity Hartnell; Jane Collier; Virginia Ammendola; Mariarosaria Del Sorbo; Annette Von Delft; Cinzia Traboni; Adrian V S Hill; Stefano Colloca; Alfredo Nicosia; Riccardo Cortese; Paul Klenerman; Antonella Folgori; Eleanor Barnes. "Highly-Immunogenic Virally-Vectored T-cell Vaccines Cannot Overcome Subversion of the T-cell Response by HCV during Chronic Infection." Vaccines (2016).

Epitope: NS3 1243-1257
Chemical type: Peptide from protein
Sequence: AYAAQGYKVLVLNPS
Position: 1243-1257
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NS4A 1675-1689
Chemical type: Peptide from protein
Sequence: LTTGSVVIVGRIILS
Position: 1675-1689
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NS4A 1675-1689
Chemical type: Peptide from protein
Sequence: LTTGSVVIVGRIILS
Position: 1675-1689
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NS5A 2124-2133
Chemical type: Peptide from protein
Sequence: EVDGVRLHRY
Position: 2124-2133
Source molecule (GenBank): AAC15725.1
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NS5A 2124-2133
Chemical type: Peptide from protein
Sequence: EVDGVRLHRY
Position: 2124-2133
Source molecule (GenBank): AAC15725.1
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NS5B 2963-2971
Chemical type: Peptide from protein
Sequence: PASSQLDLSGWFVAG
Assay category: TCell
Result: Positive
Host: M 38 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NS5B 2963-2971
Chemical type: Peptide from protein
Sequence: PASSQLDLSGWFVAG
Assay category: TCell
Result: Positive
Host: M 38 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 1406-1415
Chemical type: Peptide from protein
Sequence: KLSGLGINAV
Position: 1406-1415
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Negative
Host:  36-59 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 1406-1415
Chemical type: Peptide from protein
Sequence: KLSGLGINAV
Position: 1406-1415
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Negative
Host: M 38 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 1406-1415
Chemical type: Peptide from protein
Sequence: KLSGLGINAV
Position: 1406-1415
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  36-59 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 1406-1415
Chemical type: Peptide from protein
Sequence: KLSGLGINAV
Position: 1406-1415
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host: M 38-52 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 1406-1415
Chemical type: Peptide from protein
Sequence: KLSGLGINAV
Position: 1406-1415
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  36-59 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 1406-1415
Chemical type: Peptide from protein
Sequence: KLSGLGINAV
Position: 1406-1415
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 1406-1415
Chemical type: Peptide from protein
Sequence: KLSGLGINAV
Position: 1406-1415
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive-Low
Host: M 58
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCV polyprotein 1406-1415
Chemical type: Peptide from protein
Sequence: KLSGLGINAV
Position: 1406-1415
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive-Low
Host: M 38 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCV polyprotein 2984-2992
Chemical type: Peptide from protein
Sequence: SRARPRWFM
Position: 2984-2992
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Negative
Host: M 59 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 2984-2992
Chemical type: Peptide from protein
Sequence: SRARPRWFM
Position: 2984-2992
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host: M 59 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 1243-1257
Chemical type: Peptide from protein
Sequence: AYAAQGYKVLVLNPS
Position: 1243-1257
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 1243-1257
Chemical type: Peptide from protein
Sequence: AYAAQGYKVLVLNPS
Position: 1243-1257
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 1555-1569
Chemical type: Peptide from protein
Sequence: LEFWESVFTGLTHID
Position: 1555-1569
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 1555-1569
Chemical type: Peptide from protein
Sequence: LEFWESVFTGLTHID
Position: 1555-1569
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 1555-1569
Chemical type: Peptide from protein
Sequence: LEFWESVFTGLTHID
Position: 1555-1569
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 1555-1569
Chemical type: Peptide from protein
Sequence: LEFWESVFTGLTHID
Position: 1555-1569
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 2123-2137
Chemical type: Peptide from protein
Sequence: TEVDGVRLHRYAPAC
Position: 2123-2137
Source molecule (GenBank): ADY38596.1
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 2123-2137
Chemical type: Peptide from protein
Sequence: TEVDGVRLHRYAPAC
Position: 2123-2137
Source molecule (GenBank): ADY38596.1
Assay category: TCell
Result: Positive
Host: F 49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 1395-1403
Chemical type: Peptide from protein
Sequence: HSKKKCDEL
Position: 1395-1403
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host: M 35 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV polyprotein 1395-1403
Chemical type: Peptide from protein
Sequence: HSKKKCDEL
Position: 1395-1403
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Negative
Host: M 35 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1a polyprotein 1395-1403
Chemical type: Peptide from protein
Sequence: HSKRKCDEL
Position: 1395-1403
Source molecule (GenBank): ACJ37193.1
Assay category: TCell
Result: Positive-Low
Host: M 35 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1a polyprotein 2985-2993
Chemical type: Peptide from protein
Sequence: SRARPRWFW
Position: 2985-2993
Source molecule (GenBank): AGN33310.1
Assay category: TCell
Result: Positive-Low
Host: M 59 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1b polyprotein 1408-1417
Chemical type: Peptide from protein
Sequence: KLSALGLNAV
Position: 1408-1417
Source molecule (GenBank): BAP15757.1
Assay category: TCell
Result: Negative
Host: M 38 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1a polyprotein 1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1406-1415
Source molecule (GenBank): ACJ37172.1
Assay category: TCell
Result: Negative
Host: F 51 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo