Reference: Jack Wade; Nina Štrancar; Monica L Fernández-Quintero; Suzana Siebenhaar; Tom Jansen; Edward P W Meier; Timothy P Jenkins; Sara P Bjørn; Giang T T Nguyen; Bruno Lomonte; José Maria Gutiérrez; Christoffer V Sørensen; Johannes R Loeffler; Arijit Paul; Tulika Tulika; Johnny Arnsdorf; Sanne Schoffelen; Emil V S Lundquist; Jennifer Sørensen; Andrew B Ward; Bjørn G Voldborg; Markus-Frederik Bohn; Esperanza Rivera-de-Torre; J Preben Morth; Andreas H Laustsen. "Rational design of antibodies with pH-dependent antigen-binding properties using structural insights from broadly neutralizing antibodies against α-neurotoxins." mAbs (2025).

Epitope: Epitope of scFv A01 on alpha-cobratoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T6, P7, D8, I9, W25, D27, F29, I32, R33, G34, K35, R36, V37, D38, F65, P66, T67, R68, R70
Source molecule (GenBank): P01391.1
Assay category: BCell
Result: Positive
Quantitative measurement: 46.4

Epitope: Epitope of scFv A01 on alpha-cobratoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T6, P7, D8, I9, W25, D27, F29, I32, R33, G34, K35, R36, V37, D38, F65, P66, T67, R68, R70
Source molecule (GenBank): P01391.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.55

Epitope: Epitope of scFv A01 on alpha-cobratoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T6, P7, D8, I9, W25, D27, F29, I32, R33, G34, K35, R36, V37, D38, F65, P66, T67, R68, R70
Source molecule (GenBank): P01391.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.6

Epitope: Epitope of scFv A01 on alpha-cobratoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T6, P7, D8, I9, W25, D27, F29, I32, R33, G34, K35, R36, V37, D38, F65, P66, T67, R68, R70
Source molecule (GenBank): P01391.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.49

Epitope: Epitope of scFv A01 on alpha-cobratoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T6, P7, D8, I9, W25, D27, F29, I32, R33, G34, K35, R36, V37, D38, F65, P66, T67, R68, R70
Source molecule (GenBank): P01391.1
Assay category: BCell
Result: Positive
Quantitative measurement: 21.0

Epitope: Epitope of scFv A01 on alpha-cobratoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T6, P7, D8, I9, W25, D27, F29, I32, R33, G34, K35, R36, V37, D38, F65, P66, T67, R68, R70
Source molecule (GenBank): P01391.1
Assay category: BCell
Result: Positive
Quantitative measurement: 44000.0

Epitope: Epitope of scFv A01 on alpha-cobratoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T6, P7, D8, I9, W25, D27, F29, I32, R33, G34, K35, R36, V37, D38, F65, P66, T67, R68, R70
Source molecule (GenBank): P01391.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 3090.0

Epitope: Epitope of scFv A01 on alpha-cobratoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T6, P7, D8, I9, W25, D27, F29, I32, R33, G34, K35, R36, V37, D38, F65, P66, T67, R68, R70
Source molecule (GenBank): P01391.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00075

Epitope: Epitope of scFv A01 on alpha-cobratoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T6, P7, D8, I9, W25, D27, F29, I32, R33, G34, K35, R36, V37, D38, F65, P66, T67, R68, R70
Source molecule (GenBank): P01391.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.1

Epitope: Epitope of scFv A01 on alpha-cobratoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T6, P7, D8, I9, W25, D27, F29, I32, R33, G34, K35, R36, V37, D38, F65, P66, T67, R68, R70
Source molecule (GenBank): P01391.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv A01 on alpha-cobratoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T6, P7, D8, I9, W25, D27, F29, I32, R33, G34, K35, R36, V37, D38, F65, P66, T67, R68, R70
Source molecule (GenBank): P01391.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00017

Epitope: Epitope of scFv A01 on alpha-cobratoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T6, P7, D8, I9, W25, D27, F29, I32, R33, G34, K35, R36, V37, D38, F65, P66, T67, R68, R70
Source molecule (GenBank): P01391.1
Assay category: BCell
Result: Positive
Quantitative measurement: 84000.0

Epitope: Epitope of scFv D11 on alpha-bungarotoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T27, T29, S30, P31, I32, W49, D51, F53, S56, R57, G58, K59, V60, V61, E62, K73, H89, P90, K91, Q92
Source molecule (GenBank): P60615.1
Assay category: BCell
Result: Positive
Quantitative measurement: 13000.0

Epitope: Epitope of scFv D11 on alpha-bungarotoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T27, T29, S30, P31, I32, W49, D51, F53, S56, R57, G58, K59, V60, V61, E62, K73, H89, P90, K91, Q92
Source molecule (GenBank): P60615.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0047

Epitope: Epitope of scFv D11 on alpha-bungarotoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T27, T29, S30, P31, I32, W49, D51, F53, S56, R57, G58, K59, V60, V61, E62, K73, H89, P90, K91, Q92
Source molecule (GenBank): P60615.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.4

Epitope: Epitope of scFv D11 on alpha-bungarotoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T27, T29, S30, P31, I32, W49, D51, F53, S56, R57, G58, K59, V60, V61, E62, K73, H89, P90, K91, Q92
Source molecule (GenBank): P60615.1
Assay category: BCell
Result: Positive
Quantitative measurement: 121000.0

Epitope: Epitope of scFv D11 on alpha-bungarotoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T27, T29, S30, P31, I32, W49, D51, F53, S56, R57, G58, K59, V60, V61, E62, K73, H89, P90, K91, Q92
Source molecule (GenBank): P60615.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00015

Epitope: Epitope of scFv D11 on alpha-bungarotoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T27, T29, S30, P31, I32, W49, D51, F53, S56, R57, G58, K59, V60, V61, E62, K73, H89, P90, K91, Q92
Source molecule (GenBank): P60615.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00012

Epitope: Epitope of scFv D11 on alpha-bungarotoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T27, T29, S30, P31, I32, W49, D51, F53, S56, R57, G58, K59, V60, V61, E62, K73, H89, P90, K91, Q92
Source molecule (GenBank): P60615.1
Assay category: BCell
Result: Positive
Quantitative measurement: 115.9

Epitope: Epitope of scFv D11 on alpha-bungarotoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T27, T29, S30, P31, I32, W49, D51, F53, S56, R57, G58, K59, V60, V61, E62, K73, H89, P90, K91, Q92
Source molecule (GenBank): P60615.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.8

Epitope: Epitope of scFv D11 on alpha-bungarotoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T27, T29, S30, P31, I32, W49, D51, F53, S56, R57, G58, K59, V60, V61, E62, K73, H89, P90, K91, Q92
Source molecule (GenBank): P60615.1
Assay category: BCell
Result: Positive
Quantitative measurement: 65000.0

Epitope: Epitope of scFv D11 on alpha-bungarotoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T27, T29, S30, P31, I32, W49, D51, F53, S56, R57, G58, K59, V60, V61, E62, K73, H89, P90, K91, Q92
Source molecule (GenBank): P60615.1
Assay category: BCell
Result: Positive
Quantitative measurement: 31.3

Epitope: Epitope of scFv D11 on alpha-bungarotoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T27, T29, S30, P31, I32, W49, D51, F53, S56, R57, G58, K59, V60, V61, E62, K73, H89, P90, K91, Q92
Source molecule (GenBank): P60615.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.32

Epitope: Epitope of scFv D11 on alpha-bungarotoxin
Chemical type: Discontinuous protein residues
Discontinuous residues: T27, T29, S30, P31, I32, W49, D51, F53, S56, R57, G58, K59, V60, V61, E62, K73, H89, P90, K91, Q92
Source molecule (GenBank): P60615.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.33