Reference: Junbao Yang; I-Ting Chow; Tomasz Sosinowski; Nadia Torres-Chinn; Carla J Greenbaum; Eddie A James; John W Kappler; Howard W Davidson; William W Kwok. "Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes." Proceedings of the National Academy of Sciences of the United States of America (2014).

Epitope: B:11-23
Chemical type: Peptide from protein
Sequence: LVEALYLVCGERG
Position: 19-31
Source molecule (GenBank): AEG19452.1
Assay category: TCell
Result: Positive-Low
Host: M 13-38 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: B:11-23
Chemical type: Peptide from protein
Sequence: LVEALYLVCGERG
Position: 19-31
Source molecule (GenBank): AEG19452.1
Assay category: TCell
Result: Negative
Host:  22-68 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B:11-23
Chemical type: Peptide from protein
Sequence: LVEALYLVCGERG
Position: 19-31
Source molecule (GenBank): AEG19452.1
Assay category: TCell
Result: Negative
Host:  9-38 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B:11-23
Chemical type: Peptide from protein
Sequence: LVEALYLVCGERG
Position: 19-31
Source molecule (GenBank): AEG19452.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10.4

Epitope: B:11-23R22E
Chemical type: Peptide, no natural source
Sequence: LVEALYLVCGEEG
Assay category: TCell
Result: Positive
Host: M 13-21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: B:11-23R22E
Chemical type: Peptide, no natural source
Sequence: LVEALYLVCGEEG
Assay category: TCell
Result: Positive-Low
Host: M 13-21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: B:11-23R22E
Chemical type: Peptide, no natural source
Sequence: LVEALYLVCGEEG
Assay category: TCell
Result: Positive
Host: M 13-21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: B:11-23R22E
Chemical type: Peptide, no natural source
Sequence: LVEALYLVCGEEG
Assay category: TCell
Result: Positive
Host: M 13-21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: B:11-23R22E
Chemical type: Peptide, no natural source
Sequence: LVEALYLVCGEEG
Assay category: TCell
Result: Positive
Host:  9-38 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B:11-23R22E
Chemical type: Peptide, no natural source
Sequence: LVEALYLVCGEEG
Assay category: TCell
Result: Negative
Host:  22 and 68 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B:11-23R22E
Chemical type: Peptide, no natural source
Sequence: LVEALYLVCGEEG
Assay category: TCell
Result: Positive
Host: M 13-28 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: B:11-23R22E
Chemical type: Peptide, no natural source
Sequence: LVEALYLVCGEEG
Assay category: TCell
Result: Positive
Host: M 38 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: B:11-23R22E
Chemical type: Peptide, no natural source
Sequence: LVEALYLVCGEEG
Assay category: TCell
Result: Positive
Host: M 38 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: B:11-23R22E
Chemical type: Peptide, no natural source
Sequence: LVEALYLVCGEEG
Assay category: TCell
Result: Positive
Host: M 13 and 21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: B:11-23R22E
Chemical type: Peptide, no natural source
Sequence: LVEALYLVCGEEG
Assay category: TCell
Result: Positive
Host: M 13 and 21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: B:11-23R22E
Chemical type: Peptide, no natural source
Sequence: LVEALYLVCGEEG
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 1.6

Epitope: MP(185–204)
Chemical type: Peptide from protein
Sequence: TAKAMEQMAGSSEQAAEAME
Position: 185-204
Source molecule (GenBank): ABG80283.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1400.0

Epitope: I72C-R3
Chemical type: Peptide, no natural source
Sequence: VEELYLVAGEEGC
Assay category: TCell
Result: Positive
Host: M 13-21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: V65C-R3
Chemical type: Peptide, no natural source
Sequence: VEELYLVCGEEGG
Assay category: TCell
Result: Positive
Host: M 13-21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Bacteroides salanitronis Peptide
Chemical type: Peptide from protein
Sequence: GNALFLLCGEEVKI
Position: 161-174
Source molecule (GenBank): YP_004259638.1
Assay category: TCell
Result: Positive
Host: M 13-21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Clostridium acetobutylicum Peptide
Chemical type: Peptide from protein
Sequence: IKELYLICGEDKW
Position: 203-215
Source molecule (GenBank): NP_348681.1
Assay category: TCell
Result: Positive
Host: M 13-21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Treponema phagedenis Peptide
Chemical type: Peptide from protein
Sequence: SEADALYLVSSEEVLY
Position: 202-217
Source molecule (GenBank): ZP_08037042.1
Assay category: TCell
Result: Positive
Host: M 13-21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone