Reference: E V Nagy; H B Burch; K Mahoney; Y G Lukes; J C Morris; K D Burman. "Graves' IgG recognizes linear epitopes in the human thyrotropin receptor." Biochemical and biophysical research communications (1992).

Epitope: TSHR (1-20)
Chemical type: Peptide from protein
Sequence: MGCSSPPCECHQEEDFRVTC
Position: 22-41
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (1-20)
Chemical type: Peptide from protein
Sequence: MGCSSPPCECHQEEDFRVTC
Position: 22-41
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (16-35)
Chemical type: Peptide from protein
Sequence: FRVTCKDIQRIPSLPPSTQT
Position: 37-56
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (16-35)
Chemical type: Peptide from protein
Sequence: FRVTCKDIQRIPSLPPSTQT
Position: 37-56
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: TSHR (31-50)
Chemical type: Peptide from protein
Sequence: PSTQTLKLIETHLRTIPSHA
Position: 52-71
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive-Low

Epitope: TSHR (31-50)
Chemical type: Peptide from protein
Sequence: PSTQTLKLIETHLRTIPSHA
Position: 52-71
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (46-65)
Chemical type: Peptide from protein
Sequence: IPSHAFSNLPNISRIYVSIA
Assay category: BCell
Result: Positive

Epitope: TSHR (46-65)
Chemical type: Peptide from protein
Sequence: IPSHAFSNLPNISRIYVSIA
Assay category: BCell
Result: Negative

Epitope: TSHR (61-80)
Chemical type: Peptide from protein
Sequence: YVSIDVTLQQLESHSFYNLS
Position: 82-101
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: TSHR (61-80)
Chemical type: Peptide from protein
Sequence: YVSIDVTLQQLESHSFYNLS
Position: 82-101
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (91-110)
Chemical type: Peptide from protein
Sequence: RNLTYIDPDALKELPLLKFL
Position: 112-131
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive-Low

Epitope: TSHR (91-110)
Chemical type: Peptide from protein
Sequence: RNLTYIDPDALKELPLLKFL
Position: 112-131
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (106-125)
Chemical type: Peptide from protein
Sequence: LLKFLGIFNTGLKMFPDLTK
Position: 127-146
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (106-125)
Chemical type: Peptide from protein
Sequence: LLKFLGIFNTGLKMFPDLTK
Position: 127-146
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive-Low

Epitope: TSHR (121-140)
Chemical type: Peptide from protein
Sequence: PDLTKVYSTDIFFILEITDN
Position: 142-161
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive-High

Epitope: TSHR (121-140)
Chemical type: Peptide from protein
Sequence: PDLTKVYSTDIFFILEITDN
Position: 142-161
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive-High

Epitope: TSHR (136-155)
Chemical type: Peptide from protein
Sequence: EITDNPYMTSIPVNAFQGLC
Position: 157-176
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (136-155)
Chemical type: Peptide from protein
Sequence: EITDNPYMTSIPVNAFQGLC
Position: 157-176
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive-Low

Epitope: TSHR (151-170)
Chemical type: Peptide from protein
Sequence: FQGLCNETLTLKLYNNGFTS
Position: 172-191
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: TSHR (151-170)
Chemical type: Peptide from protein
Sequence: FQGLCNETLTLKLYNNGFTS
Position: 172-191
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: TSHR (166-185)
Chemical type: Peptide from protein
Sequence: NGFTSVQGYAFNGTKLDAVT
Assay category: BCell
Result: Negative

Epitope: TSHR (166-185)
Chemical type: Peptide from protein
Sequence: NGFTSVQGYAFNGTKLDAVT
Assay category: BCell
Result: Positive

Epitope: TSHR (181-200)
Chemical type: Peptide from protein
Sequence: LDAVYLNKNKYLTVIDKDAF
Position: 202-221
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (181-200)
Chemical type: Peptide from protein
Sequence: LDAVYLNKNKYLTVIDKDAF
Position: 202-221
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (196-215)
Chemical type: Peptide from protein
Sequence: DKDAFGGVYSGPSLLDVSQT
Position: 217-236
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (196-215)
Chemical type: Peptide from protein
Sequence: DKDAFGGVYSGPSLLDVSQT
Position: 217-236
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (211-230)
Chemical type: Peptide from protein
Sequence: DVSQTSVTALPSKGLEHLKE
Position: 232-251
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (211-230)
Chemical type: Peptide from protein
Sequence: DVSQTSVTALPSKGLEHLKE
Position: 232-251
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive-Low

Epitope: TSHR (226-245)
Chemical type: Peptide from protein
Sequence: EHLKELIARNTWTLKKLPLS
Position: 247-266
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (226-245)
Chemical type: Peptide from protein
Sequence: EHLKELIARNTWTLKKLPLS
Position: 247-266
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive-Low

Epitope: TSHR (241-260)
Chemical type: Peptide from protein
Sequence: KLPLSLSFLHLTRADLSYPS
Position: 262-281
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: TSHR (241-260)
Chemical type: Peptide from protein
Sequence: KLPLSLSFLHLTRADLSYPS
Position: 262-281
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (256-275)
Chemical type: Peptide from protein
Sequence: LSYPSHCCAFKNQKKIRGIL
Position: 277-296
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive-High

Epitope: TSHR (256-275)
Chemical type: Peptide from protein
Sequence: LSYPSHCCAFKNQKKIRGIL
Position: 277-296
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (271-290)
Chemical type: Peptide from protein
Sequence: IRGILESLMCNESSMQSLRQ
Position: 292-311
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive-Low

Epitope: TSHR (271-290)
Chemical type: Peptide from protein
Sequence: IRGILESLMCNESSMQSLRQ
Position: 292-311
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (286-305)
Chemical type: Peptide from protein
Sequence: QSLRQRKSVNALNSPLHQEY
Position: 307-326
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive-Low

Epitope: TSHR (286-305)
Chemical type: Peptide from protein
Sequence: QSLRQRKSVNALNSPLHQEY
Position: 307-326
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (301-320)
Chemical type: Peptide from protein
Sequence: LHQEYEENLGDSIVGYKEKS
Position: 322-341
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: TSHR (301-320)
Chemical type: Peptide from protein
Sequence: LHQEYEENLGDSIVGYKEKS
Position: 322-341
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (316-335)
Chemical type: Peptide from protein
Sequence: YKEKSKFQDTHNNAHYYVFF
Position: 337-356
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive-High

Epitope: TSHR (316-335)
Chemical type: Peptide from protein
Sequence: YKEKSKFQDTHNNAHYYVFF
Position: 337-356
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (346-365)
Chemical type: Peptide from protein
Sequence: GQELKNPQEETLQAFDSHYD
Position: 367-386
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: TSHR (346-365)
Chemical type: Peptide from protein
Sequence: GQELKNPQEETLQAFDSHYD
Position: 367-386
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (361-380)
Chemical type: Peptide from protein
Sequence: DSHYDYTICGDSEDMVCTPK
Position: 382-401
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: TSHR (361-380)
Chemical type: Peptide from protein
Sequence: DSHYDYTICGDSEDMVCTPK
Position: 382-401
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: EC-1
Chemical type: Peptide from protein
Sequence: DLYTHSEYYNHAIDWQTGPGC
Position: 474-494
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: EC-1
Chemical type: Peptide from protein
Sequence: DLYTHSEYYNHAIDWQTGPGC
Position: 474-494
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: EC-2
Chemical type: Peptide from protein
Sequence: SSYAKVSICLPMDTETPLAL
Position: 561-580
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: EC-2
Chemical type: Peptide from protein
Sequence: SSYAKVSICLPMDTETPLAL
Position: 561-580
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: EC-3
Chemical type: Peptide from protein
Sequence: NKPLITVTNSKY
Assay category: BCell
Result: Negative

Epitope: EC-3
Chemical type: Peptide from protein
Sequence: NKPLITVTNSKY
Assay category: BCell
Result: Negative