Reference: Shuqin Gu; Zhipeng Liu; Li Lin; Shihong Zhong; Yanchen Ma; Xiaoyi Li; Guofu Ye; Chunhua Wen; Yongyin Li; Libo Tang. "Identification and Mapping of HBsAg Loss-Related B-Cell Linear Epitopes in Chronic HBV Patients by Peptide Array." Frontiers in immunology (2021).

Epitope: S1
Chemical type: Peptide from protein
Sequence: MGGWSSKPRKGMGTN
Position: 1-15
Source molecule (GenBank): Q9QBF0.1
Assay category: BCell
Result: Positive-High

Epitope: S2
Chemical type: Peptide from protein
Sequence: SSKPRKGMGTNLSVP
Position: 5-19
Source molecule (GenBank): Q9E6S4.1
Assay category: BCell
Result: Negative

Epitope: S3
Chemical type: Peptide from protein
Sequence: RKGMGTNLSVPNPLG
Position: 9-23
Source molecule (GenBank): Q4R1R8.1
Assay category: BCell
Result: Positive-Low

Epitope: S4
Chemical type: Peptide from protein
Sequence: GTNLSVPNPLGFFPD
Position: 13-27
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-Low

Epitope: S5
Chemical type: Peptide from protein
Sequence: SVPNPLGFFPDHQLD
Position: 17-31
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-Low

Epitope: S6
Chemical type: Peptide from protein
Sequence: PLGFFPDHQLDPAFG
Position: 21-35
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-Low

Epitope: S7
Chemical type: Peptide from protein
Sequence: FPDHQLDPAFGANSN
Position: 25-39
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-Low

Epitope: S8
Chemical type: Peptide from protein
Sequence: QLDPAFGANSNNPDW
Position: 29-43
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-Low

Epitope: S9
Chemical type: Peptide from protein
Sequence: AFGANSNNPDWDFNP
Position: 33-47
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive

Epitope: S10
Chemical type: Peptide from protein
Sequence: NSNNPDWDFNPNKDT
Position: 26-40
Source molecule (GenBank): A0A096ZU61.1
Assay category: BCell
Result: Positive-Low

Epitope: S12
Chemical type: Peptide from protein
Sequence: FNPNKDTWPDANKVG
Position: 34-48
Source molecule (GenBank): P03138.3
Assay category: BCell
Result: Positive-Low

Epitope: S13
Chemical type: Peptide from protein
Sequence: KDTWPDANKVGAGAF
Position: 38-52
Source molecule (GenBank): P03138.3
Assay category: BCell
Result: Positive-Low

Epitope: S14
Chemical type: Peptide from protein
Sequence: PDANKVGAGAFGPGF
Position: 42-56
Source molecule (GenBank): V5JZH5.1
Assay category: BCell
Result: Negative

Epitope: S15
Chemical type: Peptide from protein
Sequence: KVGAGAFGPGFTPPH
Position: 46-60
Source molecule (GenBank): P12911.3
Assay category: BCell
Result: Negative

Epitope: S16
Chemical type: Peptide from protein
Sequence: GAFGPGFTPPHGGLL
Position: 61-75
Source molecule (GenBank): P12934.3
Assay category: BCell
Result: Positive-Low

Epitope: S17
Chemical type: Peptide from protein
Sequence: PGFTPPHGGLLGWSP
Position: 65-79
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S18
Chemical type: Peptide from protein
Sequence: PPHGGLLGWSPQAQG
Position: 69-83
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-Low

Epitope: S19
Chemical type: Peptide from protein
Sequence: GLLGWSPQAQGILTT
Position: 73-87
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-Low

Epitope: S20
Chemical type: Peptide from protein
Sequence: WSPQAQGILTTVPAA
Position: 77-91
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S21
Chemical type: Peptide from protein
Sequence: AQGILTTVPAAPPPA
Position: 81-95
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S22
Chemical type: Peptide from protein
Sequence: LTTVPAAPPPASTNR
Position: 85-99
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive

Epitope: S23
Chemical type: Peptide from protein
Sequence: PAAPPPASTNRQSGR
Position: 89-103
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-High

Epitope: S24
Chemical type: Peptide from protein
Sequence: PPASTNRQSGRQPTP
Position: 93-107
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S26
Chemical type: Peptide from protein
Sequence: SGRQPTPLSPPLRDT
Position: 101-115
Source molecule (GenBank): Q9QBF0.1
Assay category: BCell
Result: Positive-Low

Epitope: S28
Chemical type: Peptide from protein
Sequence: SPPLRDTHPQAMQWN
Position: 109-123
Source molecule (GenBank): Q69606.2
Assay category: BCell
Result: Positive-Low

Epitope: S30
Chemical type: Peptide from protein
Sequence: PQAMQWNSTTFHQTL
Position: 106-120
Source molecule (GenBank): P03138.3
Assay category: BCell
Result: Positive-Low

Epitope: S31
Chemical type: Peptide from protein
Sequence: QWNSTTFHQTLQDPR
Position: 110-124
Source molecule (GenBank): P03138.3
Assay category: BCell
Result: Negative

Epitope: S32
Chemical type: Peptide from protein
Sequence: TTFHQTLQDPRVRGL
Position: 114-128
Source molecule (GenBank): P03138.3
Assay category: BCell
Result: Positive-Low

Epitope: S33
Chemical type: Peptide from protein
Sequence: QTLQDPRVRGLYFPA
Position: 118-132
Source molecule (GenBank): P03138.3
Assay category: BCell
Result: Positive

Epitope: S34
Chemical type: Peptide from protein
Sequence: DPRVRGLYFPAGGSS
Position: 133-147
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive

Epitope: S35
Chemical type: Peptide from protein
Sequence: RGLYFPAGGSSSGTV
Position: 137-151
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S36
Chemical type: Peptide from protein
Sequence: FPAGGSSSGTVNPVP
Position: 141-155
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S37
Chemical type: Peptide from protein
Sequence: GSSSGTVNPVPTTAS
Position: 145-159
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S39
Chemical type: Peptide from protein
Sequence: PVPTTASPISSIFSR
Position: 153-167
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S40
Chemical type: Peptide from protein
Sequence: TASPISSIFSRTGDP
Position: 157-171
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S41
Chemical type: Peptide from protein
Sequence: ISSIFSRTGDPAPNM
Position: 161-175
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S42
Chemical type: Peptide from protein
Sequence: FSRTGDPAPNMENIT
Position: 154-168
Source molecule (GenBank): P87745.1
Assay category: BCell
Result: Positive-Low

Epitope: S43
Chemical type: Peptide from protein
Sequence: GDPAPNMENITSGFL
Position: 168-182
Source molecule (GenBank): Q9IBI3.1
Assay category: BCell
Result: Negative

Epitope: S44
Chemical type: Peptide from protein
Sequence: PNMENITSGFLGPLL
Position: 172-186
Source molecule (GenBank): Q9IBI3.1
Assay category: BCell
Result: Positive

Epitope: S45
Chemical type: Peptide from protein
Sequence: NITSGFLGPLLVLQA
Position: 166-180
Source molecule (GenBank): P03138.3
Assay category: BCell
Result: Positive-High

Epitope: S46
Chemical type: Peptide from protein
Sequence: GFLGPLLVLQAGFFL
Position: 181-195
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S47
Chemical type: Peptide from protein
Sequence: PLLVLQAGFFLLTRI
Position: 185-199
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S48
Chemical type: Peptide from protein
Sequence: LQAGFFLLTRILTIP
Position: 189-203
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S49
Chemical type: Peptide from protein
Sequence: FFLLTRILTIPQSLD
Position: 193-207
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S50
Chemical type: Peptide from protein
Sequence: TRILTIPQSLDSWWT
Position: 197-211
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S51
Chemical type: Peptide from protein
Sequence: TIPQSLDSWWTSLNF
Position: 201-215
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S52
Chemical type: Peptide from protein
Sequence: SLDSWWTSLNFLGGT
Position: 194-208
Source molecule (GenBank): P03138.3
Assay category: BCell
Result: Negative

Epitope: S54
Chemical type: Peptide from protein
Sequence: LNFLGGTPVCLGQNS
Position: 213-227
Source molecule (GenBank): Q9QBF0.1
Assay category: BCell
Result: Positive-Low

Epitope: S55
Chemical type: Peptide from protein
Sequence: GGTPVCLGQNSQSPT
Position: 216-230
Source molecule (GenBank): C7DN83.1
Assay category: BCell
Result: Positive-High

Epitope: S56
Chemical type: Peptide from protein
Sequence: VCLGQNSQSPTSNHS
Position: 210-224
Source molecule (GenBank): P03138.3
Assay category: BCell
Result: Positive-Low

Epitope: S57
Chemical type: Peptide from protein
Sequence: QNSQSPTSNHSPTSC
Position: 225-239
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S58
Chemical type: Peptide from protein
Sequence: SPTSNHSPTSCPPIC
Position: 229-243
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S59
Chemical type: Peptide from protein
Sequence: NHSPTSCPPICPGYR
Position: 233-247
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S60
Chemical type: Peptide from protein
Sequence: TSCPPICPGYRWMCL
Position: 237-251
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-Low

Epitope: S62
Chemical type: Peptide from protein
Sequence: GYRWMCLRRFIIFLF
Position: 245-259
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S63
Chemical type: Peptide from protein
Sequence: MCLRRFIIFLFILLL
Position: 249-263
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S64
Chemical type: Peptide from protein
Sequence: RFIIFLFILLLCLIF
Position: 253-267
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S65
Chemical type: Peptide from protein
Sequence: FLFILLLCLIFLLVL
Position: 257-271
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-Low

Epitope: S68
Chemical type: Peptide from protein
Sequence: LVLLDYQGMLPVCPL
Position: 269-283
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive

Epitope: S69
Chemical type: Peptide from protein
Sequence: DYQGMLPVCPLIPGS
Position: 262-276
Source molecule (GenBank): P03138.3
Assay category: BCell
Result: Negative

Epitope: S70
Chemical type: Peptide from protein
Sequence: MLPVCPLIPGSSTTS
Position: 266-280
Source molecule (GenBank): P03138.3
Assay category: BCell
Result: Negative

Epitope: S71
Chemical type: Peptide from protein
Sequence: CPLIPGSSTTSTGPC
Position: 270-284
Source molecule (GenBank): P03138.3
Assay category: BCell
Result: Positive-Low

Epitope: S72
Chemical type: Peptide from protein
Sequence: PGSSTTSTGPCKTCT
Position: 285-299
Source molecule (GenBank): Q9QBF0.1
Assay category: BCell
Result: Negative

Epitope: S73
Chemical type: Peptide from protein
Sequence: TTSTGPCKTCTTPAQ
Position: 289-303
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive

Epitope: S74
Chemical type: Peptide from protein
Sequence: GPCKTCTTPAQGTSM
Position: 293-307
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-Low

Epitope: S75
Chemical type: Peptide from protein
Sequence: TCTTPAQGTSMFPSC
Position: 297-311
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-Low

Epitope: S76
Chemical type: Peptide from protein
Sequence: PAQGTSMFPSCCCTK
Position: 301-315
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-High

Epitope: S77
Chemical type: Peptide from protein
Sequence: TSMFPSCCCTKPSDG
Position: 305-319
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive

Epitope: S78
Chemical type: Peptide from protein
Sequence: PSCCCTKPSDGNCTC
Position: 309-323
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive

Epitope: S79
Chemical type: Peptide from protein
Sequence: CTKPSDGNCTCIPIP
Position: 313-327
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-Low

Epitope: S80
Chemical type: Peptide from protein
Sequence: SDGNCTCIPIPSSWA
Position: 317-331
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-Low

Epitope: S81
Chemical type: Peptide from protein
Sequence: CTCIPIPSSWAFAKF
Position: 321-335
Source molecule (GenBank): Q9E6S4.1
Assay category: BCell
Result: Negative

Epitope: S82
Chemical type: Peptide from protein
Sequence: PIPSSWAFAKFLWEW
Position: 325-339
Source molecule (GenBank): Q9E6S4.1
Assay category: BCell
Result: Negative

Epitope: S83
Chemical type: Peptide from protein
Sequence: SWAFAKFLWEWASVR
Position: 329-343
Source molecule (GenBank): Q9E6S4.1
Assay category: BCell
Result: Positive-Low

Epitope: S86
Chemical type: Peptide from protein
Sequence: SVRFSWLSLLVPFVQ
Position: 341-355
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S87
Chemical type: Peptide from protein
Sequence: SWLSLLVPFVQWFVG
Position: 334-348
Source molecule (GenBank): P03138.3
Assay category: BCell
Result: Negative

Epitope: S88
Chemical type: Peptide from protein
Sequence: LLVPFVQWFVGLSPT
Position: 338-352
Source molecule (GenBank): P03138.3
Assay category: BCell
Result: Negative

Epitope: S89
Chemical type: Peptide from protein
Sequence: FVQWFVGLSPTVWLS
Position: 342-356
Source molecule (GenBank): P03138.3
Assay category: BCell
Result: Positive-High

Epitope: S90
Chemical type: Peptide from protein
Sequence: FVGLSPTVWLSVIWM
Position: 346-360
Source molecule (GenBank): P03138.3
Assay category: BCell
Result: Positive-Low

Epitope: S91
Chemical type: Peptide from protein
Sequence: SPTVWLSVIWMMWYW
Position: 361-375
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive

Epitope: S92
Chemical type: Peptide from protein
Sequence: WLSVIWMMWYWGPSL
Position: 365-379
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-Low

Epitope: S94
Chemical type: Peptide from protein
Sequence: WYWGPSLYNILSPFL
Position: 373-387
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-Low

Epitope: S96
Chemical type: Peptide from protein
Sequence: NILSPFLPLLPIFFC
Position: 381-395
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive

Epitope: S97
Chemical type: Peptide from protein
Sequence: PFLPLLPIFFCLWVY
Position: 385-399
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Negative

Epitope: S98
Chemical type: Peptide from protein
Sequence: FLPLLPIFFCLWVYI
Position: 386-400
Source molecule (GenBank): P31868.2
Assay category: BCell
Result: Positive-Low

Epitope: C09
Chemical type: Peptide from protein
Sequence: DPYKEFGASVELLSF
Position: 4-18
Source molecule (GenBank): Q76R61.1
Assay category: BCell
Result: Positive-Low

Epitope: C10
Chemical type: Peptide from protein
Sequence: EFGASVELLSFLPSD
Position: 8-22
Source molecule (GenBank): Q76R61.1
Assay category: BCell
Result: Positive-Low

Epitope: C11
Chemical type: Peptide from protein
Sequence: SVELLSFLPSDFFPS
Position: 12-26
Source molecule (GenBank): Q76R61.1
Assay category: BCell
Result: Positive-Low

Epitope: C12
Chemical type: Peptide from protein
Sequence: LSFLPSDFFPSIRDL
Position: 16-30
Source molecule (GenBank): Q76R61.1
Assay category: BCell
Result: Positive

Epitope: C13
Chemical type: Peptide from protein
Sequence: PSDFFPSIRDLLDTA
Position: 20-34
Source molecule (GenBank): Q76R61.1
Assay category: BCell
Result: Positive

Epitope: C16
Chemical type: Peptide from protein
Sequence: DTASALYREALESPE
Position: 32-46
Source molecule (GenBank): Q76R61.1
Assay category: BCell
Result: Positive

Epitope: C22
Chemical type: Peptide from protein
Sequence: RQAILCWGELMNLAT
Position: 56-70
Source molecule (GenBank): Q76R61.1
Assay category: BCell
Result: Positive

Epitope: C25
Chemical type: Peptide from protein
Sequence: LATWVGSNLEDPASR
Position: 68-82
Source molecule (GenBank): Q76R61.1
Assay category: BCell
Result: Positive-Low

Epitope: C28
Chemical type: Peptide from protein
Sequence: ASRELVVSYVNVNMG
Position: 80-94
Source molecule (GenBank): Q76R61.1
Assay category: BCell
Result: Positive-Low

Epitope: C36
Chemical type: Peptide from protein
Sequence: RETVLEYLVSFGVWI
Position: 112-126
Source molecule (GenBank): Q76R61.1
Assay category: BCell
Result: Positive

Epitope: C37
Chemical type: Peptide from protein
Sequence: LEYLVSFGVWIRTPP
Position: 116-130
Source molecule (GenBank): Q76R61.1
Assay category: BCell
Result: Positive-High

Epitope: C40
Chemical type: Peptide from protein
Sequence: TPPAYRPPNAPILST
Position: 128-142
Source molecule (GenBank): Q76R61.1
Assay category: BCell
Result: Positive

Epitope: C41
Chemical type: Peptide from protein
Sequence: YRPPNAPILSTLPET
Position: 132-146
Source molecule (GenBank): Q76R61.1
Assay category: BCell
Result: Positive-Low

Epitope: C42
Chemical type: Peptide from protein
Sequence: NAPILSTLPETTVVR
Position: 136-150
Source molecule (GenBank): Q76R61.1
Assay category: BCell
Result: Positive-Low

Epitope: C44
Chemical type: Peptide from protein
Sequence: PETTVVRRRGRSPRR
Position: 144-158
Source molecule (GenBank): Q76R61.1
Assay category: BCell
Result: Positive-Low

Epitope: P15
Chemical type: Peptide from protein
Sequence: GNFTGLYSSTVPVFN
Position: 57-71
Source molecule (GenBank): P03155.1
Assay category: BCell
Result: Positive-Low

Epitope: P24
Chemical type: Peptide from protein
Sequence: EQFVGPLTVNEKRRL
Position: 93-107
Source molecule (GenBank): P03155.1
Assay category: BCell
Result: Positive-Low

Epitope: P26
Chemical type: Peptide from protein
Sequence: VNEKRRLKLIMPARF
Position: 101-115
Source molecule (GenBank): P03155.1
Assay category: BCell
Result: Positive

Epitope: P27
Chemical type: Peptide from protein
Sequence: RRLKLIMPARFYPNV
Position: 105-119
Source molecule (GenBank): Q9PX62.1
Assay category: BCell
Result: Positive-Low

Epitope: P30
Chemical type: Peptide from protein
Sequence: PNVTKYLPLDKGIKP
Position: 117-131
Source molecule (GenBank): Q9PX62.1
Assay category: BCell
Result: Positive-Low

Epitope: P35
Chemical type: Peptide from protein
Sequence: LVNHYFQTRHYLHTL
Position: 137-151
Source molecule (GenBank): P03155.1
Assay category: BCell
Result: Positive-Low

Epitope: P93
Chemical type: Peptide from protein
Sequence: VTGGVFLVDKNPHNT
Position: 358-372
Source molecule (GenBank): P03155.1
Assay category: BCell
Result: Positive-Low

Epitope: P94
Chemical type: Peptide from protein
Sequence: VFLVDKNPHNTTESR
Position: 21-35
Source molecule (GenBank): A0A161J4U8.1
Assay category: BCell
Result: Positive-Low

Epitope: P106
Chemical type: Peptide from protein
Sequence: SNLSWLSLDVSAAFY
Position: 410-424
Source molecule (GenBank): P03155.1
Assay category: BCell
Result: Positive-Low

Epitope: P114
Chemical type: Peptide from protein
Sequence: GLSRYVARLSSNSRI
Position: 442-456
Source molecule (GenBank): P03155.1
Assay category: BCell
Result: Positive-Low

Epitope: P123
Chemical type: Peptide from protein
Sequence: SLLLLYKTFGRKLHL
Position: 137-151
Source molecule (GenBank): A0A161J4U8.1
Assay category: BCell
Result: Positive

Epitope: P128
Chemical type: Peptide from protein
Sequence: ILGFRKIPMGVGLSP
Position: 498-512
Source molecule (GenBank): P03155.1
Assay category: BCell
Result: Positive-Low

Epitope: P137
Chemical type: Peptide from protein
Sequence: LAFSYMDDVVLGAKS
Position: 534-548
Source molecule (GenBank): P03155.1
Assay category: BCell
Result: Positive-Low

Epitope: P146
Chemical type: Peptide from protein
Sequence: LNPNKTKRWGYSLNF
Position: 570-584
Source molecule (GenBank): P03155.1
Assay category: BCell
Result: Positive-Low

Epitope: P188
Chemical type: Peptide from protein
Sequence: NSVVLSRKYTSFPWL
Position: 738-752
Source molecule (GenBank): P12900.1
Assay category: BCell
Result: Positive