Reference: E C Andersson; B E Hansen; H Jacobsen; L S Madsen; C B Andersen; J Engberg; J B Rothbard; G S McDevitt; V Malmström; R Holmdahl; A Svejgaard; L Fugger. "Definition of MHC and T cell receptor contacts in the HLA-DR4restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice." Proceedings of the National Academy of Sciences of the United States of America (1998).

Epitope: CII (261-273)
Chemical type: Peptide from protein
Sequence: AGFKGEQGPKGEP
Position: 461-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: CII (261-273)
Chemical type: Peptide from protein
Sequence: AGFKGEQGPKGEP
Position: 461-473
Source molecule (GenBank): P02458.3
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 180.0

Epitope: CII 262A
Chemical type: Peptide, no natural source
Sequence: AAFKGEQGPKGEP
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 52.0

Epitope: CII 263A
Chemical type: Peptide, no natural source
Sequence: AGAKGEQGPKGEP
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 35000.0

Epitope: CII 264A
Chemical type: Peptide, no natural source
Sequence: AGFAGEQGPKGEP
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 2022.0

Epitope: CII 265A
Chemical type: Peptide, no natural source
Sequence: AGFKAEQGPKGEP
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 21.0

Epitope: CII 267A
Chemical type: Peptide, no natural source
Sequence: AGFKGEAGPKGEP
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 115.0

Epitope: CII 268A
Chemical type: Peptide, no natural source
Sequence: AGFKGEQAPKGEP
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 65.0

Epitope: CII 270A
Chemical type: Peptide, no natural source
Sequence: AGFKGEQGPAGEP
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 77.0

Epitope: CII 271A
Chemical type: Peptide, no natural source
Sequence: AGFKGEQGPKAEP
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 40.0

Epitope: CII 272A
Chemical type: Peptide, no natural source
Sequence: AGFKGEQGPKGAP
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 24.0

Epitope: CII 273A
Chemical type: Peptide, no natural source
Sequence: AGFKGEQGPKGEA
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 429.0

Epitope: CII 263N
Chemical type: Peptide, no natural source
Sequence: AGNKGEQGPKGEP
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 35000.0

Epitope: CII 263S
Chemical type: Peptide, no natural source
Sequence: AGSKGEQGPKGEP
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 35000.0

Epitope: CII 236Y
Chemical type: Peptide, no natural source
Sequence: AGYKGEQGPKGEP
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 541.0

Epitope: CII 266D
Chemical type: Peptide, no natural source
Sequence: AGFKGDQGPKGEP
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 2222.0

Epitope: CII 266K
Chemical type: Peptide, no natural source
Sequence: AGFKGKQGPKGEP
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 35000.0

Epitope: CII 266R
Chemical type: Peptide, no natural source
Sequence: AGFKGRQGPKGEP
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 35000.0