Reference: Linling He; Netanel Tzarum; Xiaohe Lin; Benjamin Shapero; Cindy Sou; Colin J Mann; Armando Stano; Lei Zhang; Kenna Nagy; Erick Giang; Mansun Law; Ian A Wilson; Jiang Zhu. "Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines." Science advances (2020).

Epitope: Epitope of AR3A Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: I422, L427, N428, C429, N430, D431, Q434, I438, T439, L441, F442, Y443, W531, E533, Y619
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.38

Epitope: Epitope of E1 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: R424, T512, V516, T521, L524, G525, I526, P527, M540, E542, S543, L544, R545, P546, P547, T548, G549, G550, W551, G640, I642
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.38

Epitope: Epitope of AR3C on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L44, N45, C46, E48, G53, L55, A56, L58, F59, Y60, W146
Source molecule (GenBank): YP_009709863.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.6

Epitope: Epitope of AR3C on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L44, N45, C46, E48, G53, L55, A56, L58, F59, Y60, W146
Source molecule (GenBank): YP_009709863.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.67

Epitope: Epitope of AR3C on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L44, N45, C46, E48, G53, L55, A56, L58, F59, Y60, W146
Source molecule (GenBank): YP_009709863.1
Assay category: BCell
Result: Positive
Quantitative measurement: 17.3

Epitope: Epitope of AR3C on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L44, N45, C46, E48, G53, L55, A56, L58, F59, Y60, W146
Source molecule (GenBank): YP_009709863.1
Assay category: BCell
Result: Positive
Quantitative measurement: 19.5

Epitope: Epitope of AR3C on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L44, N45, C46, E48, G53, L55, A56, L58, F59, Y60, W146
Source molecule (GenBank): YP_009709863.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.85

Epitope: Epitope of AR3C on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L44, N45, C46, E48, G53, L55, A56, L58, F59, Y60, W146
Source molecule (GenBank): YP_009709863.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.9

Epitope: Epitope of AR3B on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: I422, L427, N428, C429, N430, D431, Q434, T435, I438, T439, L441, F442, Y443, R502, W531, E533, Y619
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.06

Epitope: Epitope of AR3B on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: I422, L427, N428, C429, N430, D431, Q434, T435, I438, T439, L441, F442, Y443, R502, W531, E533, Y619
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.06