Reference: Katharina N Steinitz; Pauline M van Helden; Brigitte Binder; David C Wraith; Sabine Unterthurner; Corinna Hermann; Maria Schuster; Rafi U Ahmad; Markus Weiller; Christian Lubich; Maurus de la Rosa; Hans Peter Schwarz; Birgit M Reipert. "CD4+ T-cell epitopes associated with antibody responses after intravenously and subcutaneously applied human FVIII in humanized hemophilic E17 HLA-DRB1*1501 mice." Blood (2012).

Epitope: FVIII P1
Chemical type: Peptide from protein
Sequence: AKVSSFPSIRPIYLT
Position: 1410-1424
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 643.8

Epitope: FVIII P1
Chemical type: Peptide from protein
Sequence: AKVSSFPSIRPIYLT
Position: 1410-1424
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative

Epitope: FVIII P1
Chemical type: Peptide from protein
Sequence: AKVSSFPSIRPIYLT
Position: 1410-1424
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 7200.0

Epitope: FVIII P1
Chemical type: Peptide from protein
Sequence: AKVSSFPSIRPIYLT
Position: 1410-1424
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 354.0

Epitope: FVIII P1
Chemical type: Peptide from protein
Sequence: AKVSSFPSIRPIYLT
Position: 1410-1424
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 626.4

Epitope: FVIII P1
Chemical type: Peptide from protein
Sequence: AKVSSFPSIRPIYLT
Position: 1410-1424
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 460.2

Epitope: FVIII P2
Chemical type: Peptide from protein
Sequence: AWPKMHTVNGYVNRS
Position: 246-260
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 25.8

Epitope: FVIII P2
Chemical type: Peptide from protein
Sequence: AWPKMHTVNGYVNRS
Position: 246-260
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative

Epitope: FVIII P2
Chemical type: Peptide from protein
Sequence: AWPKMHTVNGYVNRS
Position: 246-260
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 140.4

Epitope: FVIII P2
Chemical type: Peptide from protein
Sequence: AWPKMHTVNGYVNRS
Position: 246-260
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1633.2

Epitope: FVIII P2
Chemical type: Peptide from protein
Sequence: AWPKMHTVNGYVNRS
Position: 246-260
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1737.6

Epitope: FVIII P2
Chemical type: Peptide from protein
Sequence: AWPKMHTVNGYVNRS
Position: 246-260
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 4320.0

Epitope: FVIII P3
Chemical type: Peptide from protein
Sequence: DNIMVTFRNQASRPY
Position: 1788-1802
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 483.0

Epitope: FVIII P3
Chemical type: Peptide from protein
Sequence: DNIMVTFRNQASRPY
Position: 1788-1802
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 551.4

Epitope: FVIII P3
Chemical type: Peptide from protein
Sequence: DNIMVTFRNQASRPY
Position: 1788-1802
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 529.2

Epitope: FVIII P3
Chemical type: Peptide from protein
Sequence: DNIMVTFRNQASRPY
Position: 1788-1802
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 876.0

Epitope: FVIII P3
Chemical type: Peptide from protein
Sequence: DNIMVTFRNQASRPY
Position: 1788-1802
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 15000.0

Epitope: FVIII P3
Chemical type: Peptide from protein
Sequence: DNIMVTFRNQASRPY
Position: 1788-1802
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 15000.0

Epitope: FVIII P4
Chemical type: Peptide from protein
Sequence: EVEDNIMVTFRNQAS
Position: 1785-1799
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 904.8

Epitope: FVIII P4
Chemical type: Peptide from protein
Sequence: EVEDNIMVTFRNQAS
Position: 1785-1799
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1265.4

Epitope: FVIII P4
Chemical type: Peptide from protein
Sequence: EVEDNIMVTFRNQAS
Position: 1785-1799
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 328.8

Epitope: FVIII P4
Chemical type: Peptide from protein
Sequence: EVEDNIMVTFRNQAS
Position: 1785-1799
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative

Epitope: FVIII P4
Chemical type: Peptide from protein
Sequence: EVEDNIMVTFRNQAS
Position: 1785-1799
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 514.8

Epitope: FVIII P4
Chemical type: Peptide from protein
Sequence: EVEDNIMVTFRNQAS
Position: 1785-1799
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 236.4

Epitope: FVIII P5
Chemical type: Peptide from protein
Sequence: GDTLLIIFKNQASRP
Position: 477-491
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 467.4

Epitope: FVIII P5
Chemical type: Peptide from protein
Sequence: GDTLLIIFKNQASRP
Position: 477-491
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 567.0

Epitope: FVIII P5
Chemical type: Peptide from protein
Sequence: GDTLLIIFKNQASRP
Position: 477-491
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 452.4

Epitope: FVIII P5
Chemical type: Peptide from protein
Sequence: GDTLLIIFKNQASRP
Position: 477-491
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 951.0

Epitope: FVIII P5
Chemical type: Peptide from protein
Sequence: GDTLLIIFKNQASRP
Position: 477-491
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 324.6

Epitope: FVIII P5
Chemical type: Peptide from protein
Sequence: GDTLLIIFKNQASRP
Position: 477-491
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 550.8

Epitope: FVIII P6
Chemical type: Peptide from protein
Sequence: GEVGDTLLIIFKNQA
Position: 474-488
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 15000.0

Epitope: FVIII P6
Chemical type: Peptide from protein
Sequence: GEVGDTLLIIFKNQA
Position: 474-488
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative

Epitope: FVIII P6
Chemical type: Peptide from protein
Sequence: GEVGDTLLIIFKNQA
Position: 474-488
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 708.0

Epitope: FVIII P6
Chemical type: Peptide from protein
Sequence: GEVGDTLLIIFKNQA
Position: 474-488
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1329.0

Epitope: FVIII P6
Chemical type: Peptide from protein
Sequence: GEVGDTLLIIFKNQA
Position: 474-488
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 639.0

Epitope: FVIII P6
Chemical type: Peptide from protein
Sequence: GEVGDTLLIIFKNQA
Position: 474-488
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 771.0

Epitope: FVIII P7
Chemical type: Peptide from protein
Sequence: GMSTLFLVYSNKCQT
Position: 2028-2042
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 393.6

Epitope: FVIII P7
Chemical type: Peptide from protein
Sequence: GMSTLFLVYSNKCQT
Position: 2028-2042
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1177.8

Epitope: FVIII P7
Chemical type: Peptide from protein
Sequence: GMSTLFLVYSNKCQT
Position: 2028-2042
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 217.2

Epitope: FVIII P7
Chemical type: Peptide from protein
Sequence: GMSTLFLVYSNKCQT
Position: 2028-2042
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 955.8

Epitope: FVIII P7
Chemical type: Peptide from protein
Sequence: GMSTLFLVYSNKCQT
Position: 2028-2042
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 628.8

Epitope: FVIII P7
Chemical type: Peptide from protein
Sequence: GMSTLFLVYSNKCQT
Position: 2028-2042
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 3568.2

Epitope: FVIII P8
Chemical type: Peptide from protein
Sequence: IIARYIRLHPTHYSI
Position: 2163-2177
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 413.4

Epitope: FVIII P8
Chemical type: Peptide from protein
Sequence: IIARYIRLHPTHYSI
Position: 2163-2177
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative

Epitope: FVIII P8
Chemical type: Peptide from protein
Sequence: IIARYIRLHPTHYSI
Position: 2163-2177
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 590.4

Epitope: FVIII P8
Chemical type: Peptide from protein
Sequence: IIARYIRLHPTHYSI
Position: 2163-2177
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 351.0

Epitope: FVIII P8
Chemical type: Peptide from protein
Sequence: IIARYIRLHPTHYSI
Position: 2163-2177
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 555.0

Epitope: FVIII P8
Chemical type: Peptide from protein
Sequence: IIARYIRLHPTHYSI
Position: 2163-2177
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 323.4

Epitope: FVIII P9
Chemical type: Peptide from protein
Sequence: ITLKNMASHPVSLHA
Position: 105-119
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative

Epitope: FVIII P9
Chemical type: Peptide from protein
Sequence: ITLKNMASHPVSLHA
Position: 105-119
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 3694.2

Epitope: FVIII P9
Chemical type: Peptide from protein
Sequence: ITLKNMASHPVSLHA
Position: 105-119
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1786.8

Epitope: FVIII P9
Chemical type: Peptide from protein
Sequence: ITLKNMASHPVSLHA
Position: 105-119
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 7200.0

Epitope: FVIII P9
Chemical type: Peptide from protein
Sequence: ITLKNMASHPVSLHA
Position: 105-119
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 959.4

Epitope: FVIII P9
Chemical type: Peptide from protein
Sequence: ITLKNMASHPVSLHA
Position: 105-119
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 498.0

Epitope: FVIII P10
Chemical type: Peptide from protein
Sequence: KMHTVNGYVNRSLPG
Position: 249-263
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 177.0

Epitope: FVIII P10
Chemical type: Peptide from protein
Sequence: KMHTVNGYVNRSLPG
Position: 249-263
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative

Epitope: FVIII P10
Chemical type: Peptide from protein
Sequence: KMHTVNGYVNRSLPG
Position: 249-263
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 266.4

Epitope: FVIII P10
Chemical type: Peptide from protein
Sequence: KMHTVNGYVNRSLPG
Position: 249-263
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 223.2

Epitope: FVIII P10
Chemical type: Peptide from protein
Sequence: KMHTVNGYVNRSLPG
Position: 249-263
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 639.6

Epitope: FVIII P10
Chemical type: Peptide from protein
Sequence: KMHTVNGYVNRSLPG
Position: 249-263
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1680.0

Epitope: FVIII P11
Chemical type: Peptide from protein
Sequence: KNMASHPVSLHAVGV
Position: 108-122
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1078.8

Epitope: FVIII P11
Chemical type: Peptide from protein
Sequence: KNMASHPVSLHAVGV
Position: 108-122
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 543.6

Epitope: FVIII P11
Chemical type: Peptide from protein
Sequence: KNMASHPVSLHAVGV
Position: 108-122
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1057.2

Epitope: FVIII P11
Chemical type: Peptide from protein
Sequence: KNMASHPVSLHAVGV
Position: 108-122
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 7200.0

Epitope: FVIII P11
Chemical type: Peptide from protein
Sequence: KNMASHPVSLHAVGV
Position: 108-122
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 422.4

Epitope: FVIII P11
Chemical type: Peptide from protein
Sequence: KNMASHPVSLHAVGV
Position: 108-122
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 273.6

Epitope: FVIII P12
Chemical type: Peptide from protein
Sequence: LHAGMSTLFLVYSNK
Position: 2025-2039
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 519.6

Epitope: FVIII P12
Chemical type: Peptide from protein
Sequence: LHAGMSTLFLVYSNK
Position: 2025-2039
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 2182.8

Epitope: FVIII P12
Chemical type: Peptide from protein
Sequence: LHAGMSTLFLVYSNK
Position: 2025-2039
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 2461.8

Epitope: FVIII P12
Chemical type: Peptide from protein
Sequence: LHAGMSTLFLVYSNK
Position: 2025-2039
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 7200.0

Epitope: FVIII P12
Chemical type: Peptide from protein
Sequence: LHAGMSTLFLVYSNK
Position: 2025-2039
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 906.6

Epitope: FVIII P12
Chemical type: Peptide from protein
Sequence: LHAGMSTLFLVYSNK
Position: 2025-2039
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 748.2

Epitope: FVIII P14
Chemical type: Peptide from protein
Sequence: LPIAKVSSFPSIRPI
Position: 1407-1421
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative

Epitope: FVIII P14
Chemical type: Peptide from protein
Sequence: LPIAKVSSFPSIRPI
Position: 1407-1421
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 475.2

Epitope: FVIII P14
Chemical type: Peptide from protein
Sequence: LPIAKVSSFPSIRPI
Position: 1407-1421
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 616.2

Epitope: FVIII P14
Chemical type: Peptide from protein
Sequence: LPIAKVSSFPSIRPI
Position: 1407-1421
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 246.6

Epitope: FVIII P14
Chemical type: Peptide from protein
Sequence: LPIAKVSSFPSIRPI
Position: 1407-1421
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 201.0

Epitope: FVIII P14
Chemical type: Peptide from protein
Sequence: LPIAKVSSFPSIRPI
Position: 1407-1421
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 154.8

Epitope: FVIII P15
Chemical type: Peptide from protein
Sequence: MVTFRNQASRPYSFY
Position: 1791-1805
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1056.0

Epitope: FVIII P15
Chemical type: Peptide from protein
Sequence: MVTFRNQASRPYSFY
Position: 1791-1805
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1140.0

Epitope: FVIII P15
Chemical type: Peptide from protein
Sequence: MVTFRNQASRPYSFY
Position: 1791-1805
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 7200.0

Epitope: FVIII P15
Chemical type: Peptide from protein
Sequence: MVTFRNQASRPYSFY
Position: 1791-1805
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1198.2

Epitope: FVIII P15
Chemical type: Peptide from protein
Sequence: MVTFRNQASRPYSFY
Position: 1791-1805
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1080.6

Epitope: FVIII P15
Chemical type: Peptide from protein
Sequence: MVTFRNQASRPYSFY
Position: 1791-1805
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative

Epitope: FVIII P16
Chemical type: Peptide from protein
Sequence: NPPIIARYIRLHPTH
Position: 2160-2174
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 451.8

Epitope: FVIII P16
Chemical type: Peptide from protein
Sequence: NPPIIARYIRLHPTH
Position: 2160-2174
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 15000.0

Epitope: FVIII P16
Chemical type: Peptide from protein
Sequence: NPPIIARYIRLHPTH
Position: 2160-2174
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 531.0

Epitope: FVIII P16
Chemical type: Peptide from protein
Sequence: NPPIIARYIRLHPTH
Position: 2160-2174
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 320.4

Epitope: FVIII P16
Chemical type: Peptide from protein
Sequence: NPPIIARYIRLHPTH
Position: 2160-2174
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 247.2

Epitope: FVIII P16
Chemical type: Peptide from protein
Sequence: NPPIIARYIRLHPTH
Position: 2160-2174
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 868.8

Epitope: FVIII P17
Chemical type: Peptide from protein
Sequence: PTKSDPRCLTRYYSS
Position: 540-554
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 427.2

Epitope: FVIII P17
Chemical type: Peptide from protein
Sequence: PTKSDPRCLTRYYSS
Position: 540-554
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 555.6

Epitope: FVIII P17
Chemical type: Peptide from protein
Sequence: PTKSDPRCLTRYYSS
Position: 540-554
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 298.2

Epitope: FVIII P17
Chemical type: Peptide from protein
Sequence: PTKSDPRCLTRYYSS
Position: 540-554
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 131.4

Epitope: FVIII P17
Chemical type: Peptide from protein
Sequence: PTKSDPRCLTRYYSS
Position: 540-554
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 15000.0

Epitope: FVIII P17
Chemical type: Peptide from protein
Sequence: PTKSDPRCLTRYYSS
Position: 540-554
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 15000.0

Epitope: FVIII P19
Chemical type: Peptide from protein
Sequence: RCLTRYYSSFVNMER
Position: 546-560
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 956.4

Epitope: FVIII P19
Chemical type: Peptide from protein
Sequence: RCLTRYYSSFVNMER
Position: 546-560
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 160.2

Epitope: FVIII P19
Chemical type: Peptide from protein
Sequence: RCLTRYYSSFVNMER
Position: 546-560
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative

Epitope: FVIII P19
Chemical type: Peptide from protein
Sequence: RCLTRYYSSFVNMER
Position: 546-560
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1178.4

Epitope: FVIII P19
Chemical type: Peptide from protein
Sequence: RCLTRYYSSFVNMER
Position: 546-560
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 666.0

Epitope: FVIII P19
Chemical type: Peptide from protein
Sequence: RCLTRYYSSFVNMER
Position: 546-560
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 331.2

Epitope: FVIII P20
Chemical type: Peptide from protein
Sequence: RSPLPIAKVSSFPSI
Position: 1404-1418
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 591.0

Epitope: FVIII P20
Chemical type: Peptide from protein
Sequence: RSPLPIAKVSSFPSI
Position: 1404-1418
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative

Epitope: FVIII P20
Chemical type: Peptide from protein
Sequence: RSPLPIAKVSSFPSI
Position: 1404-1418
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 448.2

Epitope: FVIII P20
Chemical type: Peptide from protein
Sequence: RSPLPIAKVSSFPSI
Position: 1404-1418
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1489.2

Epitope: FVIII P20
Chemical type: Peptide from protein
Sequence: RSPLPIAKVSSFPSI
Position: 1404-1418
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1003.8

Epitope: FVIII P20
Chemical type: Peptide from protein
Sequence: RSPLPIAKVSSFPSI
Position: 1404-1418
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 453.0

Epitope: FVIII P21
Chemical type: Peptide from protein
Sequence: RYIRLHPTHYSIRST
Position: 2166-2180
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 427.8

Epitope: FVIII P21
Chemical type: Peptide from protein
Sequence: RYIRLHPTHYSIRST
Position: 2166-2180
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative

Epitope: FVIII P21
Chemical type: Peptide from protein
Sequence: RYIRLHPTHYSIRST
Position: 2166-2180
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 546.6

Epitope: FVIII P21
Chemical type: Peptide from protein
Sequence: RYIRLHPTHYSIRST
Position: 2166-2180
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 519.0

Epitope: FVIII P21
Chemical type: Peptide from protein
Sequence: RYIRLHPTHYSIRST
Position: 2166-2180
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 351.6

Epitope: FVIII P21
Chemical type: Peptide from protein
Sequence: RYIRLHPTHYSIRST
Position: 2166-2180
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 197.4

Epitope: FVIII P22
Chemical type: Peptide from protein
Sequence: SDPRCLTRYYSSFVN
Position: 543-557
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 336.6

Epitope: FVIII P22
Chemical type: Peptide from protein
Sequence: SDPRCLTRYYSSFVN
Position: 543-557
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative

Epitope: FVIII P22
Chemical type: Peptide from protein
Sequence: SDPRCLTRYYSSFVN
Position: 543-557
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 547.2

Epitope: FVIII P22
Chemical type: Peptide from protein
Sequence: SDPRCLTRYYSSFVN
Position: 543-557
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 199.2

Epitope: FVIII P22
Chemical type: Peptide from protein
Sequence: SDPRCLTRYYSSFVN
Position: 543-557
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 382.2

Epitope: FVIII P22
Chemical type: Peptide from protein
Sequence: SDPRCLTRYYSSFVN
Position: 543-557
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 179.4

Epitope: FVIII P23
Chemical type: Peptide from protein
Sequence: TLFLVYSNKCQTPLG
Position: 2031-2045
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 3951.6

Epitope: FVIII P23
Chemical type: Peptide from protein
Sequence: TLFLVYSNKCQTPLG
Position: 2031-2045
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 15000.0

Epitope: FVIII P23
Chemical type: Peptide from protein
Sequence: TLFLVYSNKCQTPLG
Position: 2031-2045
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1089.0

Epitope: FVIII P23
Chemical type: Peptide from protein
Sequence: TLFLVYSNKCQTPLG
Position: 2031-2045
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 7200.0

Epitope: FVIII P23
Chemical type: Peptide from protein
Sequence: TLFLVYSNKCQTPLG
Position: 2031-2045
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1527.0

Epitope: FVIII P23
Chemical type: Peptide from protein
Sequence: TLFLVYSNKCQTPLG
Position: 2031-2045
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1494.0

Epitope: FVIII P24
Chemical type: Peptide from protein
Sequence: TVNGYVNRSLPGLIG
Position: 252-266
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 400.2

Epitope: FVIII P24
Chemical type: Peptide from protein
Sequence: TVNGYVNRSLPGLIG
Position: 252-266
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 3598.2

Epitope: FVIII P24
Chemical type: Peptide from protein
Sequence: TVNGYVNRSLPGLIG
Position: 252-266
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1080.0

Epitope: FVIII P24
Chemical type: Peptide from protein
Sequence: TVNGYVNRSLPGLIG
Position: 252-266
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 301.2

Epitope: FVIII P24
Chemical type: Peptide from protein
Sequence: TVNGYVNRSLPGLIG
Position: 252-266
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative

Epitope: FVIII P24
Chemical type: Peptide from protein
Sequence: TVNGYVNRSLPGLIG
Position: 252-266
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 2615.4

Epitope: FVIII P25
Chemical type: Peptide from protein
Sequence: TVVITLKNMASHPVS
Position: 102-116
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1041.0

Epitope: FVIII P25
Chemical type: Peptide from protein
Sequence: TVVITLKNMASHPVS
Position: 102-116
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 15000.0

Epitope: FVIII P25
Chemical type: Peptide from protein
Sequence: TVVITLKNMASHPVS
Position: 102-116
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 919.2

Epitope: FVIII P25
Chemical type: Peptide from protein
Sequence: TVVITLKNMASHPVS
Position: 102-116
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 483.0

Epitope: FVIII P25
Chemical type: Peptide from protein
Sequence: TVVITLKNMASHPVS
Position: 102-116
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1829.4

Epitope: FVIII P25
Chemical type: Peptide from protein
Sequence: TVVITLKNMASHPVS
Position: 102-116
Source molecule (GenBank): AAA52484.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 263.4

Epitope: HA (306-318)
Chemical type: Peptide from protein
Sequence: PKYVKQNTLKLAT
Position: 306-318
Source molecule (GenBank): 0704243A
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 346.2

Epitope: HA (306-318)
Chemical type: Peptide from protein
Sequence: PKYVKQNTLKLAT
Position: 306-318
Source molecule (GenBank): 0704243A
Assay category: MhcBinding
Result: Negative

Epitope: HA (306-318)
Chemical type: Peptide from protein
Sequence: PKYVKQNTLKLAT
Position: 306-318
Source molecule (GenBank): 0704243A
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 352.2

Epitope: HA (306-318)
Chemical type: Peptide from protein
Sequence: PKYVKQNTLKLAT
Position: 306-318
Source molecule (GenBank): 0704243A
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 361.8

Epitope: HA (306-318)
Chemical type: Peptide from protein
Sequence: PKYVKQNTLKLAT
Position: 306-318
Source molecule (GenBank): 0704243A
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 645.0

Epitope: HA (306-318)
Chemical type: Peptide from protein
Sequence: PKYVKQNTLKLAT
Position: 306-318
Source molecule (GenBank): 0704243A
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 2299.2

Epitope: Myoglobin
Chemical type: Peptide from protein
Sequence: LFRKDIAAKYKE
Position: 138-149
Source molecule (GenBank): P02185.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 701.4

Epitope: Myoglobin
Chemical type: Peptide from protein
Sequence: LFRKDIAAKYKE
Position: 138-149
Source molecule (GenBank): P02185.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1066.0

Epitope: Myoglobin
Chemical type: Peptide from protein
Sequence: LFRKDIAAKYKE
Position: 138-149
Source molecule (GenBank): P02185.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 450.0

Epitope: Myoglobin
Chemical type: Peptide from protein
Sequence: LFRKDIAAKYKE
Position: 138-149
Source molecule (GenBank): P02185.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 324.6

Epitope: Myoglobin
Chemical type: Peptide from protein
Sequence: LFRKDIAAKYKE
Position: 138-149
Source molecule (GenBank): P02185.2
Assay category: MhcBinding
Result: Negative

Epitope: Myoglobin
Chemical type: Peptide from protein
Sequence: LFRKDIAAKYKE
Position: 138-149
Source molecule (GenBank): P02185.2
Assay category: MhcBinding
Result: Negative

Epitope: hMBP (84-102)
Chemical type: Peptide from protein
Sequence: NPVVHFFKNIVTPRTPPPS
Position: 85-103
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Negative

Epitope: hMBP (84-102)
Chemical type: Peptide from protein
Sequence: NPVVHFFKNIVTPRTPPPS
Position: 85-103
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 845.4

Epitope: hMBP (84-102)
Chemical type: Peptide from protein
Sequence: NPVVHFFKNIVTPRTPPPS
Position: 85-103
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 762.0

Epitope: hMBP (84-102)
Chemical type: Peptide from protein
Sequence: NPVVHFFKNIVTPRTPPPS
Position: 85-103
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 12000.0

Epitope: hMBP (84-102)
Chemical type: Peptide from protein
Sequence: NPVVHFFKNIVTPRTPPPS
Position: 85-103
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 646.2

Epitope: hMBP (84-102)
Chemical type: Peptide from protein
Sequence: NPVVHFFKNIVTPRTPPPS
Position: 85-103
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 264.0

Epitope: FVIII (83-103)
Chemical type: Peptide from protein
Sequence: TVVITLKNMASHPVSLHAVGV
Position: 102-122
Source molecule (GenBank): AAA52484.1
Assay category: TCell
Result: Positive-Low
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII (227-247)
Chemical type: Peptide from protein
Sequence: AWPKMHTVNGYVNRSLPGLIG
Position: 246-266
Source molecule (GenBank): AAA52484.1
Assay category: TCell
Result: Positive-Low
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII (521-541)
Chemical type: Peptide from protein
Sequence: PTKSDPRCLTRYYSSFVNMER
Position: 540-560
Source molecule (GenBank): AAA52484.1
Assay category: TCell
Result: Positive-High
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII (1382-1405)
Chemical type: Peptide from protein
Sequence: QANRSPLPIAKVSSFPSIRPIYLT
Position: 1401-1424
Source molecule (GenBank): AAA52484.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII (2006-2026)
Chemical type: Peptide from protein
Sequence: LHAGMSTLFLVYSNKCQTPLG
Position: 2025-2045
Source molecule (GenBank): AAA52484.1
Assay category: TCell
Result: Positive-Low
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII (2141-2161)
Chemical type: Peptide from protein
Sequence: TGVTTQGVKSLLTSMYVKEFL
Position: 2260-2280
Source molecule (GenBank): AAA52484.1
Assay category: TCell
Result: Positive-Low
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)