Reference: Irene Jarchum; Teresa P DiLorenzo. "Ins2 deficiency augments spontaneous HLA-A*0201-restricted T cell responses to insulin." Journal of immunology (Baltimore, Md. : 1950) (2010).

Epitope: B15-23
Chemical type: Peptide from protein
Sequence: LYLVCGERG
Position: 39-47
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-Low
Host: F 7 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Ins1/2 A13-21
Chemical type: Peptide from protein
Sequence: LYQLENYCN
Position: 100-108
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-High
Host: F 7-8 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Ins1/2 A13-21
Chemical type: Peptide from protein
Sequence: LYQLENYCN
Position: 100-108
Source molecule (GenBank): P01325.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: Ins1/2 A13-21
Chemical type: Peptide from protein
Sequence: LYQLENYCN
Position: 100-108
Source molecule (GenBank): P01325.1
Assay category: MhcBinding
Result: Negative

Epitope: Ins1/2 A11-19 M9
Chemical type: Peptide, no natural source
Sequence: CSLYQLENM
Assay category: MhcBinding
Result: Positive

Epitope: Ins1/2 A11-19 M9
Chemical type: Peptide, no natural source
Sequence: CSLYQLENM
Assay category: MhcBinding
Result: Negative

Epitope: Ins1/2 A13-21 M9
Chemical type: Peptide, no natural source
Sequence: LYQLENYCM
Assay category: MhcBinding
Result: Positive

Epitope: Ins1/2 A13-21 M9
Chemical type: Peptide, no natural source
Sequence: LYQLENYCM
Assay category: MhcBinding
Result: Negative

Epitope: Ins1/2 A11-19 S1
Chemical type: Peptide, no natural source
Sequence: SSLYQLENY
Assay category: MhcBinding
Result: Negative

Epitope: Ins1/2 A11-19 S1
Chemical type: Peptide, no natural source
Sequence: SSLYQLENY
Assay category: MhcBinding
Result: Negative

Epitope: Ins1/2 A13-21 S8
Chemical type: Peptide, no natural source
Sequence: LYQLENYSN
Assay category: MhcBinding
Result: Negative

Epitope: Ins1/2 A13-21 S8
Chemical type: Peptide, no natural source
Sequence: LYQLENYSN
Assay category: MhcBinding
Result: Negative

Epitope: MimA2
Chemical type: Peptide, no natural source
Sequence: YAIENYLEL
Assay category: MhcBinding
Result: Positive

Epitope: NRP-V7
Chemical type: Peptide, no natural source
Sequence: KYNKANVFL
Assay category: MhcBinding
Result: Positive

Epitope: Ins B10-18
Chemical type: Peptide from protein
Sequence: HLVEALYLV
Position: 34-42
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive
Host: F 12-13 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Ins B10-18
Chemical type: Peptide from protein
Sequence: HLVEALYLV
Position: 34-42
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Ins1 L3-11
Chemical type: Peptide from protein
Sequence: LLVHFLPLL
Position: 3-11
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-Low
Host: F 7-8 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Ins1 L3-11
Chemical type: Peptide from protein
Sequence: LLVHFLPLL
Position: 3-11
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Negative
Host: F 12-13 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Ins1 B5-14
Chemical type: Peptide from protein
Sequence: HLCGPHLVEA
Position: 29-38
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-Low
Host: F 7-8 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Ins1 B5-14
Chemical type: Peptide from protein
Sequence: HLCGPHLVEA
Position: 29-38
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-Low
Host: F 12-13 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Ins A10-20
Chemical type: Peptide from protein
Sequence: ICSLYQLENYC
Position: 97-107
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Negative
Host: F 12-13 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Ins A10-20
Chemical type: Peptide from protein
Sequence: ICSLYQLENYC
Position: 97-107
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-Low
Host: F 7-8 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: Ins A10-20
Chemical type: Peptide from protein
Sequence: ICSLYQLENYC
Position: 97-107
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Negative
Host: F 9 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: IGRP 206-214
Chemical type: Peptide from protein
Sequence: VYLKTNVFL
Position: 206-214
Source molecule (GenBank): Q9Z186.1
Assay category: TCell
Result: Positive
Host: F 7-8 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: IGRP 206-214
Chemical type: Peptide from protein
Sequence: VYLKTNVFL
Position: 206-214
Source molecule (GenBank): Q9Z186.1
Assay category: TCell
Result: Positive-Low
Host: F 7-8 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: IGRP 206-214
Chemical type: Peptide from protein
Sequence: VYLKTNVFL
Position: 206-214
Source molecule (GenBank): Q9Z186.1
Assay category: TCell
Result: Positive
Host: F 12-13 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: position 99 8-mer
Chemical type: Peptide from protein
Sequence: SLYQLENY
Position: 99-106
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Negative
Host: F 9 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: position 99 10-mer
Chemical type: Peptide from protein
Sequence: ICSLYQLENY
Position: 97-106
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-Low
Host: F 9 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: position 99 11-mer
Chemical type: Peptide from protein
Sequence: SICSLYQLENY
Position: 96-106
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-Low
Host: F 9 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: position 100 9-mer
Chemical type: Peptide from protein
Sequence: SLYQLENYC
Position: 99-107
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Negative
Host: F 9 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: position 101 8-mer
Chemical type: Peptide from protein
Sequence: YQLENYCN
Position: 101-108
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-Low
Host: F 9 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: position 101 10-mer
Chemical type: Peptide from protein
Sequence: SLYQLENYCN
Position: 99-108
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Negative
Host: F 9 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: position 101 11-mer
Chemical type: Peptide from protein
Sequence: CSLYQLENYCN
Position: 98-108
Source molecule (GenBank): P01325.1
Assay category: TCell
Result: Positive-Low
Host: F 9 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo