Reference: Brian G Pierce; Zhen-Yong Keck; Ruixue Wang; Patrick Lau; Kyle Garagusi; Khadija Elkholy; Eric A Toth; Richard A Urbanowicz; Johnathan D Guest; Pragati Agnihotri; Melissa C Kerzic; Alexander Marin; Alexander K Andrianov; Jonathan K Ball; Roy A Mariuzza; Thomas R Fuerst; Steven K H Foung. "Structure-Based Design of Hepatitis C Virus E2 Glycoprotein Improves Serum Binding and Cross-Neutralization." Journal of virology (2020).

Epitope: HC84.20 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: L441, F442, Y443, Y613, W616
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: HC84.24 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: F442, Y443
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: HC33.1, HC33.4, AP33, HCV1 epitope
Chemical type: Peptide from protein
Sequence: QLINTNGSWHIN
Position: 412-423
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-High

Epitope: HC33.1, HC33.4, AP33, HCV1 epitope
Chemical type: Peptide from protein
Sequence: QLINTNGSWHIN
Position: 412-423
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive
Host: F 7-9 weeks

Epitope: HC33.1, HC33.4, AP33, HCV1 epitope
Chemical type: Peptide from protein
Sequence: QLINTNGSWHIN
Position: 412-423
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive
Quantitative measurement: 9.5

Epitope: HC33.1, HC33.4, AP33, HCV1 epitope
Chemical type: Peptide from protein
Sequence: QLINTNGSWHIN
Position: 412-423
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive
Quantitative measurement: 42.0

Epitope: HC33.1, HC33.4, AP33, HCV1 epitope
Chemical type: Peptide from protein
Sequence: QLINTNGSWHIN
Position: 412-423
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: HC33.1, HC33.4, AP33, HCV1 epitope
Chemical type: Peptide from protein
Sequence: QLINTNGSWHIN
Position: 412-423
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: HC33.1, HC33.4, AP33, HCV1 epitope
Chemical type: Peptide from protein
Sequence: QLINTNGSWHIN
Position: 412-423
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive

Epitope: AR3A epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S424, G523, P525, G530, D535, V538, N540
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-High

Epitope: AR3A epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S424, G523, P525, G530, D535, V538, N540
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.8

Epitope: HC84.1 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: L441, F442, K446
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive
Quantitative measurement: 30.0

Epitope: AR4A epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: Y201, T204, N205, D206, R657, D658, L692, D698
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: AR5A epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: Y201, T204, N205, D206, R639, R657, D658, L665, L692
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-Low

Epitope: AS434/Domain D
Chemical type: Peptide from protein
Sequence: NTGWLAGLFYQHK
Position: 434-446
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.3

Epitope: AS434/Domain D
Chemical type: Peptide from protein
Sequence: NTGWLAGLFYQHK
Position: 434-446
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive
Host: F 7-9 weeks

Epitope: AS434/Domain D
Chemical type: Peptide from protein
Sequence: NTGWLAGLFYQHK
Position: 434-446
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive-High

Epitope: AS434/Domain D
Chemical type: Peptide from protein
Sequence: NTGWLAGLFYQHK
Position: 434-446
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive