Reference: Pauline Malinge; Xavier Chauchet; Jérémie Bourguignon; Nicolas Bosson; Sébastien Calloud; Tereza Bautzova; Marie Borlet; Mette Laursen; Vinardas Kelpsas; Nadia Rose; Franck Gueneau; Ulla Ravn; Giovanni Magistrelli; Nicolas Fischer. "Structural analysis of light chain-driven bispecific antibodies targeting CD47 and PD-L1." mAbs (2024).

Epitope: Epitope of Fab K2 on CD47
Chemical type: Discontinuous protein residues
Discontinuous residues: T52, E53, Y55, K59, D69, A71, L72, T117, E118, L119, T120, E122, E124
Source molecule (GenBank): Q08722.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of Fab K2 on CD47
Chemical type: Discontinuous protein residues
Discontinuous residues: T52, E53, Y55, K59, D69, A71, L72, T117, E118, L119, T120, E122, E124
Source molecule (GenBank): Q08722.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.0

Epitope: Epitope of Fab K2 on CD47
Chemical type: Discontinuous protein residues
Discontinuous residues: T52, E53, Y55, K59, D69, A71, L72, T117, E118, L119, T120, E122, E124
Source molecule (GenBank): Q08722.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 315.0

Epitope: Epitope of Fab K2 on CD47
Chemical type: Discontinuous protein residues
Discontinuous residues: T52, E53, Y55, K59, D69, A71, L72, T117, E118, L119, T120, E122, E124
Source molecule (GenBank): Q08722.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 0.0998

Epitope: Epitope of Fab K2 on CD47
Chemical type: Discontinuous protein residues
Discontinuous residues: T52, E53, Y55, K59, D69, A71, L72, T117, E118, L119, T120, E122, E124
Source molecule (GenBank): Q08722.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 317000.0

Epitope: Epitope of Fab S79 on PD-L1
Chemical type: Discontinuous protein residues
Discontinuous residues: A18, F19, D49, A51, A52, L53, I54, Y56, E58, D61, N63, Q66, V68, H69, M115, S117, G119, G120, A121, D122, Y123
Source molecule (GenBank): Q9NZQ7.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab S79 on PD-L1
Chemical type: Discontinuous protein residues
Discontinuous residues: A18, F19, D49, A51, A52, L53, I54, Y56, E58, D61, N63, Q66, V68, H69, M115, S117, G119, G120, A121, D122, Y123
Source molecule (GenBank): Q9NZQ7.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.794

Epitope: Epitope of Fab S79 on PD-L1
Chemical type: Discontinuous protein residues
Discontinuous residues: A18, F19, D49, A51, A52, L53, I54, Y56, E58, D61, N63, Q66, V68, H69, M115, S117, G119, G120, A121, D122, Y123
Source molecule (GenBank): Q9NZQ7.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.5

Epitope: Epitope of Fab S79 on PD-L1
Chemical type: Discontinuous protein residues
Discontinuous residues: A18, F19, D49, A51, A52, L53, I54, Y56, E58, D61, N63, Q66, V68, H69, M115, S117, G119, G120, A121, D122, Y123
Source molecule (GenBank): Q9NZQ7.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000175

Epitope: Epitope of Fab S79 on PD-L1
Chemical type: Discontinuous protein residues
Discontinuous residues: A18, F19, D49, A51, A52, L53, I54, Y56, E58, D61, N63, Q66, V68, H69, M115, S117, G119, G120, A121, D122, Y123
Source molecule (GenBank): Q9NZQ7.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 329000.0