Reference: Miki Tsuruta; Shohei Ueda; Poh Yin Yew; Isao Fukuda; Sachiko Yoshimura; Hiroyuki Kishi; Hiroshi Hamana; Masatoshi Hirayama; Junji Yatsuda; Atsushi Irie; Satoru Senju; Eiji Yuba; Tomomi Kamba; Masatoshi Eto; Hideki Nakayama; Yasuharu Nishimura. "Bladder cancer-associated cancer-testis antigen-derived long peptides encompassing both CTL and promiscuous HLA class II-restricted Th cell epitopes induced CD4<sup>+</sup> T cells expressing converged T-cell receptor genes ." Oncoimmunology (2018).

Epitope: DEPDC1 191-213-LP1
Chemical type: Peptide from protein
Sequence: RYVILIYLQTILGVPSLEEVINP
Position: 191-213
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 191-213-LP1
Chemical type: Peptide from protein
Sequence: RYVILIYLQTILGVPSLEEVINP
Position: 191-213
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 191-213-LP1
Chemical type: Peptide from protein
Sequence: RYVILIYLQTILGVPSLEEVINP
Position: 191-213
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 191-213-LP1
Chemical type: Peptide from protein
Sequence: RYVILIYLQTILGVPSLEEVINP
Position: 191-213
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 191-213-LP1
Chemical type: Peptide from protein
Sequence: RYVILIYLQTILGVPSLEEVINP
Position: 191-213
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 191-213-LP1
Chemical type: Peptide from protein
Sequence: RYVILIYLQTILGVPSLEEVINP
Position: 191-213
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 191-213-LP1
Chemical type: Peptide from protein
Sequence: RYVILIYLQTILGVPSLEEVINP
Position: 191-213
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 191-213-LP1
Chemical type: Peptide from protein
Sequence: RYVILIYLQTILGVPSLEEVINP
Position: 191-213
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 301-329-LP3
Chemical type: Peptide from protein
Sequence: NILVVCGYITVSDRSSGIHKIQDDPQSSK
Position: 301-329
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 301-329-LP3
Chemical type: Peptide from protein
Sequence: NILVVCGYITVSDRSSGIHKIQDDPQSSK
Position: 301-329
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 301-329-LP3
Chemical type: Peptide from protein
Sequence: NILVVCGYITVSDRSSGIHKIQDDPQSSK
Position: 301-329
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 301-329-LP3
Chemical type: Peptide from protein
Sequence: NILVVCGYITVSDRSSGIHKIQDDPQSSK
Position: 301-329
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 301-329-LP3
Chemical type: Peptide from protein
Sequence: NILVVCGYITVSDRSSGIHKIQDDPQSSK
Position: 301-329
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 301-329-LP3
Chemical type: Peptide from protein
Sequence: NILVVCGYITVSDRSSGIHKIQDDPQSSK
Position: 301-329
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 301-329-LP3
Chemical type: Peptide from protein
Sequence: NILVVCGYITVSDRSSGIHKIQDDPQSSK
Position: 301-329
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 301-329-LP3
Chemical type: Peptide from protein
Sequence: NILVVCGYITVSDRSSGIHKIQDDPQSSK
Position: 301-329
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 301-329-LP3
Chemical type: Peptide from protein
Sequence: NILVVCGYITVSDRSSGIHKIQDDPQSSK
Position: 301-329
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 301-329-LP3
Chemical type: Peptide from protein
Sequence: NILVVCGYITVSDRSSGIHKIQDDPQSSK
Position: 301-329
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 301-329-LP3
Chemical type: Peptide from protein
Sequence: NILVVCGYITVSDRSSGIHKIQDDPQSSK
Position: 301-329
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 301-329-LP3
Chemical type: Peptide from protein
Sequence: NILVVCGYITVSDRSSGIHKIQDDPQSSK
Position: 301-329
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 301-329-LP3
Chemical type: Peptide from protein
Sequence: NILVVCGYITVSDRSSGIHKIQDDPQSSK
Position: 301-329
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 301-329-LP3
Chemical type: Peptide from protein
Sequence: NILVVCGYITVSDRSSGIHKIQDDPQSSK
Position: 301-329
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 301-329-LP3
Chemical type: Peptide from protein
Sequence: NILVVCGYITVSDRSSGIHKIQDDPQSSK
Position: 301-329
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 613-634-LP4
Chemical type: Peptide from protein
Sequence: NRRKLQLLMRMISRMSQNVDMP
Position: 613-634
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 613-634-LP4
Chemical type: Peptide from protein
Sequence: NRRKLQLLMRMISRMSQNVDMP
Position: 613-634
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 613-634-LP4
Chemical type: Peptide from protein
Sequence: NRRKLQLLMRMISRMSQNVDMP
Position: 613-634
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 613-634-LP4
Chemical type: Peptide from protein
Sequence: NRRKLQLLMRMISRMSQNVDMP
Position: 613-634
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
MHC allele types: 750 436
Host: F 57-81 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEPDC1 613-634-LP4
Chemical type: Peptide from protein
Sequence: NRRKLQLLMRMISRMSQNVDMP
Position: 613-634
Source molecule (GenBank): Q5TB30.2
Assay category: TCell
Result: Positive
MHC allele types: 412 425
Host: F 57-81 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
MHC allele types: 415 437 412 425
Host: F 57-81 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
MHC allele types: 415 437 412 425
Host: F 57-81 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
MHC allele types: 415 437 412 425
Host: F 57-81 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: other
Tissue: other
Culture conditions: Cell Line / Clone

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 272-298-LP1
Chemical type: Peptide from protein
Sequence: WVSFFEIYNEYIYDLFVPVSSKFQKRK
Position: 272-298
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
MHC allele types: 406 415 436 412 416 425
Host: F 57-81 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
MHC allele types: 406 415 436 412 416 425
Host: F 57-81 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPHOSPH1 326-351-LP2
Chemical type: Peptide from protein
Sequence: AYRLLKLGIKHQSVAFTKLNNASSRS
Position: 326-351
Source molecule (GenBank): Q96Q89.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated