Reference: S Trembleau; S Gregori; G Penna; I Gorny; L Adorini. "IL-12 administration reveals diabetogenic T cells in genetically resistant I-Ealpha-transgenic nonobese diabetic mice: resistance to autoimmune diabetes is associated with binding of Ealpha-derived peptides to the I-A(g7) molecule." Journal of immunology (Baltimore, Md. : 1950) (2001).

Epitope: HEL 10-23
Chemical type: Peptide from protein
Sequence: AAMKRHGLDNYRGY
Position: 10-23
Source molecule (GenBank): 1LKS_A
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 400.0

Epitope: HEL 10-23
Chemical type: Peptide from protein
Sequence: AAMKRHGLDNYRGY
Position: 10-23
Source molecule (GenBank): 1LKS_A
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 0.05

Epitope: Hsp 1-16
Chemical type: Peptide from protein
Sequence: MAKTIAYDEEARRGLE
Position: 1-16
Source molecule (GenBank): CAA17397.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: Hsp 1-16
Chemical type: Peptide from protein
Sequence: MAKTIAYDEEARRGLE
Position: 1-16
Source molecule (GenBank): CAA17397.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: Hsp 1-16
Chemical type: Peptide from protein
Sequence: MAKTIAYDEEARRGLE
Position: 1-16
Source molecule (GenBank): CAA17397.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 0.05

Epitope: Hsp 1-16
Chemical type: Peptide from protein
Sequence: MAKTIAYDEEARRGLE
Position: 1-16
Source molecule (GenBank): CAA17397.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 400.0

Epitope: Eα/DRα 52-68
Chemical type: Peptide from protein
Sequence: ASFEAQGALANIAVDKA
Position: 52-68
Source molecule (GenBank): 2WBJ_A
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Eα/DRα 52-68
Chemical type: Peptide from protein
Sequence: ASFEAQGALANIAVDKA
Position: 52-68
Source molecule (GenBank): 2WBJ_A
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: Eα/DRα 52-68
Chemical type: Peptide from protein
Sequence: ASFEAQGALANIAVDKA
Position: 52-68
Source molecule (GenBank): 2WBJ_A
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 0.05

Epitope: Eα/DRα 52-68
Chemical type: Peptide from protein
Sequence: ASFEAQGALANIAVDKA
Position: 52-68
Source molecule (GenBank): 2WBJ_A
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 500.0

Epitope: Eα 65-77
Chemical type: Peptide from protein
Sequence: VDKANLDVMKERS
Position: 65-77
Source molecule (GenBank): 1IEA_A
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Eα 65-77
Chemical type: Peptide from protein
Sequence: VDKANLDVMKERS
Position: 65-77
Source molecule (GenBank): 1IEA_A
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 500.0

Epitope: Eα 65-77
Chemical type: Peptide from protein
Sequence: VDKANLDVMKERS
Position: 65-77
Source molecule (GenBank): 1IEA_A
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 0.05

Epitope: DRα 65-77
Chemical type: Peptide from protein
Sequence: VDKANLEIMTKRS
Position: 65-77
Source molecule (GenBank): 2WBJ_A
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: DRα 65-77
Chemical type: Peptide from protein
Sequence: VDKANLEIMTKRS
Position: 65-77
Source molecule (GenBank): 2WBJ_A
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: DRα 65-77
Chemical type: Peptide from protein
Sequence: VDKANLEIMTKRS
Position: 65-77
Source molecule (GenBank): 2WBJ_A
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 0.05