Reference: Luis M Molinos-Albert; Eduard Baquero; Cyril Planchais; Virginie Doceul; Hicham El Costa; Estelle Mottez; Vincent Mallet; Stanislas Pol; Matthew L Albert; Nicole Pavio; Cécile Alanio; Jordan D Dimitrov; Hugo Mouquet. "Structural basis for hepatitis E virus neutralization by potent human antibodies." Science advances (2025).

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 55 years

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: F 56 years

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: F 56 years

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: F 56 years

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: F 56 years

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00033
Host: F 56 years

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: F 56 years

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: F 56 years

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.4
Host: F 56 years

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Quantitative measurement: 840000.0
Host: F 56 years

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Quantitative measurement: 380000.0
Host: F 56 years

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: F 56 years

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.81
Host: F 56 years

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00031
Host: F 56 years

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: F 56 years

Epitope: Epitope of Es4.431 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, G486, S487, S488, Y532, S533, T586, A590
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: F 56 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.41
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Quantitative measurement: 680000.0
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00028
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.27
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Quantitative measurement: 890000.0
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00024
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.9
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Quantitative measurement: 310000.0
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00049
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 61 years

Epitope: Epitope of Es5.127 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: E479, Y480, Q482, T483, T484, Y485, V494, E549, K554, Y584, T585, T586, S587, L588, A590, G591, P592, T593
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 61 years

Epitope: Epitope of Es1.114 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: V464, R466, A467, D515, S517, K518, V519, T520, L521, D522, G523, R524, P525, T528
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 55 years

Epitope: Epitope of Es1.114 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: V464, R466, A467, D515, S517, K518, V519, T520, L521, D522, G523, R524, P525, T528
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 55 years

Epitope: Epitope of Es1.114 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: V464, R466, A467, D515, S517, K518, V519, T520, L521, D522, G523, R524, P525, T528
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Negative
Host: M 55 years

Epitope: Epitope of Es1.114 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: V464, R466, A467, D515, S517, K518, V519, T520, L521, D522, G523, R524, P525, T528
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 55 years

Epitope: Epitope of Es1.114 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: V464, R466, A467, D515, S517, K518, V519, T520, L521, D522, G523, R524, P525, T528
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 55 years

Epitope: Epitope of Es1.114 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: V464, R466, A467, D515, S517, K518, V519, T520, L521, D522, G523, R524, P525, T528
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 55 years

Epitope: Epitope of Es1.114 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: V464, R466, A467, D515, S517, K518, V519, T520, L521, D522, G523, R524, P525, T528
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 55 years

Epitope: Epitope of Es1.114 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: V464, R466, A467, D515, S517, K518, V519, T520, L521, D522, G523, R524, P525, T528
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 55 years

Epitope: Epitope of Es1.114 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: V464, R466, A467, D515, S517, K518, V519, T520, L521, D522, G523, R524, P525, T528
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 55 years

Epitope: Epitope of Es1.114 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: V464, R466, A467, D515, S517, K518, V519, T520, L521, D522, G523, R524, P525, T528
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive-Low
Host: M 55 years

Epitope: Epitope of Es1.114 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: V464, R466, A467, D515, S517, K518, V519, T520, L521, D522, G523, R524, P525, T528
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 55 years

Epitope: Epitope of Es1.114 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: V464, R466, A467, D515, S517, K518, V519, T520, L521, D522, G523, R524, P525, T528
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive
Host: M 55 years

Epitope: Epitope of Es1.114 Fab on HEV Capsid
Chemical type: Discontinuous protein residues
Discontinuous residues: V464, R466, A467, D515, S517, K518, V519, T520, L521, D522, G523, R524, P525, T528
Source molecule (GenBank): AAZ30922.1
Assay category: BCell
Result: Positive