Reference: Yassmin Musthaffa; Emma E Hamilton-Williams; Hendrik J Nel; Anne-Sophie Bergot; Ahmed M Mehdi; Mark Harris; Ranjeny Thomas. "Proinsulin-specific T-cell responses correlate with estimated c-peptide and predict partial remission duration in type 1 diabetes." Clinical & translational immunology (2021).

Epitope: PI 33-63
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ
Position: 57-87
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PI 33-63
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ
Position: 57-87
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PI 33-63
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ
Position: 57-87
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-High
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PI 40-52
Chemical type: Peptide from protein
Sequence: GQVELGGGPGAGS
Position: 64-76
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PI 40-52
Chemical type: Peptide from protein
Sequence: GQVELGGGPGAGS
Position: 64-76
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-High
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PI 40-52
Chemical type: Peptide from protein
Sequence: GQVELGGGPGAGS
Position: 64-76
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: hEGGG:C-peptide
Chemical type: Spliced peptide from proteins
Position: 64-71
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: hEGGG:C-peptide
Chemical type: Spliced peptide from proteins
Position: 64-71
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: hEGGG:C-peptide
Chemical type: Spliced peptide from proteins
Position: 64-71
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-High
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: hEL:A-chain
Chemical type: Spliced peptide from proteins
Position: 76-82
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-High
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: hEL:A-chain
Chemical type: Spliced peptide from proteins
Position: 76-82
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: hEL:A-chain
Chemical type: Spliced peptide from proteins
Position: 76-82
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: hEGGG:IAPP2
Chemical type: Spliced peptide from proteins
Position: 64-71
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: hEGGG:IAPP2
Chemical type: Spliced peptide from proteins
Position: 64-71
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: hEGGG:IAPP2
Chemical type: Spliced peptide from proteins
Position: 64-71
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive-High
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo