Reference: D L Kaufman; M Clare-Salzler; J Tian; T Forsthuber; G S Ting; P Robinson; M A Atkinson; E E Sercarz; A J Tobin; P V Lehmann. "Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes." Nature (1993).

Epitope: Peptide 34
Chemical type: Peptide from protein
Sequence: IPPSLRTLEDNEERMSRLSK
Position: 509-528
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 34
Chemical type: Peptide from protein
Sequence: IPPSLRTLEDNEERMSRLSK
Position: 509-528
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host: F 3 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 35
Chemical type: Peptide from protein
Sequence: SRLSKVAPVIKARMMEYGTT
Position: 524-543
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 35
Chemical type: Peptide from protein
Sequence: SRLSKVAPVIKARMMEYGTT
Position: 524-543
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host: F 3 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 17
Chemical type: Peptide from protein
Sequence: NMYAMMIARFKMFPEVKEKG
Position: 247-266
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Host:  5-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 17
Chemical type: Peptide from protein
Sequence: NMYAMMIARFKMFPEVKEKG
Position: 247-266
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host: F 3 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 1
Chemical type: Peptide from protein
Sequence: MASPGSGFWSFGSEDGSGDS
Position: 1-20
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 2
Chemical type: Peptide from protein
Sequence: GSGDSENPGTARAWCQVAQKFTG
Position: 16-38
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 4
Chemical type: Peptide from protein
Sequence: LLYGDAEKPAESGGSQPPRA
Position: 47-66
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 3
Chemical type: Peptide from protein
Sequence: QKFTGGIGIGNKLCALLYGD
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 5
Chemical type: Peptide from protein
Sequence: QPPRAAARKAACACDQKPCSC
Position: 62-82
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 7
Chemical type: Peptide from protein
Sequence: HATDLLPACDGERPTLAFLQ
Position: 93-112
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 8
Chemical type: Peptide from protein
Sequence: LAFLQDVMNILLQYVVKSFDRS
Position: 108-129
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 9
Chemical type: Peptide from protein
Sequence: SFDRSTKVIDFHYPNELLQE
Position: 125-144
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 10
Chemical type: Peptide from protein
Sequence: ELLQEYNWELADQPQNLEEILM
Position: 140-161
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 11
Chemical type: Peptide from protein
Sequence: EEILMHCQTTLKYAIKTGHP
Position: 157-176
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 12
Chemical type: Peptide from protein
Sequence: KTGHPRYFNQLSTGLDMVGL
Position: 172-191
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 13
Chemical type: Peptide from protein
Sequence: DMVGLAADWLTSTANTNMFT
Position: 187-206
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 14
Chemical type: Peptide from protein
Sequence: TNMFTYEIAPVFVLLEYVTL
Position: 202-221
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 15
Chemical type: Peptide from protein
Sequence: EYVTLKKMREIIGWPGGSGD
Position: 217-236
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 16
Chemical type: Peptide from protein
Sequence: GGSGDGIFSPGGAISNMYAM
Position: 232-251
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 18
Chemical type: Peptide from protein
Sequence: PEVKEKGMAALPRLIAFTSE
Position: 260-279
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 19
Chemical type: Peptide from protein
Sequence: AFTSEHSHFSLKKGAAALGI
Position: 275-294
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 20
Chemical type: Peptide from protein
Sequence: AALGIGTDSVILIKCDERGK
Position: 290-309
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 21
Chemical type: Peptide from protein
Sequence: DERGKMIPSDLERRILEAKQ
Position: 305-324
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 22
Chemical type: Peptide from protein
Sequence: LEAKQKGFVPFLVSATAGTT
Position: 320-339
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 23
Chemical type: Peptide from protein
Sequence: TAGTTVYGAFDPLLAVADICKK
Position: 335-356
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Host:  7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 24
Chemical type: Peptide from protein
Sequence: DICKKYKIWMHVDAAWGGGLLMS
Position: 352-374
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 25
Chemical type: Peptide from protein
Sequence: GLLMSRKHKWKLSGVERANS
Position: 370-389
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 26
Chemical type: Peptide from protein
Sequence: ERANSVTWNPHKMMGVPLQC
Position: 385-404
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 27
Chemical type: Peptide from protein
Sequence: VPLQCSALLVREEGLMQNCNQ
Position: 400-420
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 29
Chemical type: Peptide from protein
Sequence: KHYDLSYDTGDKALQCGRHV
Position: 431-450
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 32
Chemical type: Peptide from protein
Sequence: EYLYNIIKNREGYEMVFDGK
Position: 479-498
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Host:  7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 33
Chemical type: Peptide from protein
Sequence: VFDGKPQHTMVCKWYIPPSL
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 36
Chemical type: Peptide from protein
Sequence: EYGTTMVSYQPLGDKVNFFR
Position: 539-558
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Host:  5-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 37
Chemical type: Peptide from protein
Sequence: VNFFRMVISMPAATHQDIDF
Assay category: TCell
Result: Negative
Host:  4-7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 38
Chemical type: Peptide from protein
Sequence: ATHQDIDFLIEEIERLGQDL
Position: 566-585
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Host:  7 weeks
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo