Reference: Wen-Chih Kuo; Cheng-Chung Lee; Ya-Wen Chang; Wei Pang; Hong-Sen Chen; Shin-Chen Hou; Shin-Yi Lo; An-Suei Yang; Andrew H-J Wang. "Structure-based Development of Human Interleukin-1β-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP." Journal of molecular biology (2021).

Epitope: Epitope of Fab26 on IL1ß
Chemical type: Discontinuous protein residues
Discontinuous residues: Q130, L145, H146, L147, Q148, D151, Q154, Q242, A243, E244, N245, M246, P247, G256, Q257
Source molecule (GenBank): NP_000567.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.65

Epitope: Epitope of Fab26 on IL1ß
Chemical type: Discontinuous protein residues
Discontinuous residues: Q130, L145, H146, L147, Q148, D151, Q154, Q242, A243, E244, N245, M246, P247, G256, Q257
Source molecule (GenBank): NP_000567.1
Assay category: BCell
Result: Positive
Quantitative measurement: 28.9

Epitope: Epitope of Fab26 on IL1ß
Chemical type: Discontinuous protein residues
Discontinuous residues: Q130, L145, H146, L147, Q148, D151, Q154, Q242, A243, E244, N245, M246, P247, G256, Q257
Source molecule (GenBank): NP_000567.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 0.0201

Epitope: Epitope of Fab26 on IL1ß
Chemical type: Discontinuous protein residues
Discontinuous residues: Q130, L145, H146, L147, Q148, D151, Q154, Q242, A243, E244, N245, M246, P247, G256, Q257
Source molecule (GenBank): NP_000567.1
Assay category: BCell
Result: Positive
Quantitative measurement: 724000.0

Epitope: Epitope of Fab26 on IL1ß
Chemical type: Discontinuous protein residues
Discontinuous residues: Q130, L145, H146, L147, Q148, D151, Q154, Q242, A243, E244, N245, M246, P247, G256, Q257
Source molecule (GenBank): NP_000567.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of Fab26A on IL1ß
Chemical type: Discontinuous protein residues
Discontinuous residues: Q130, L145, H146, L147, Q148, D151, Q154, Q242, A243, E244, N245, M246, G256, Q257
Source molecule (GenBank): NP_000567.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000707

Epitope: Epitope of Fab26A on IL1ß
Chemical type: Discontinuous protein residues
Discontinuous residues: Q130, L145, H146, L147, Q148, D151, Q154, Q242, A243, E244, N245, M246, G256, Q257
Source molecule (GenBank): NP_000567.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1090000.0

Epitope: Epitope of Fab26A on IL1ß
Chemical type: Discontinuous protein residues
Discontinuous residues: Q130, L145, H146, L147, Q148, D151, Q154, Q242, A243, E244, N245, M246, G256, Q257
Source molecule (GenBank): NP_000567.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab26A on IL1ß
Chemical type: Discontinuous protein residues
Discontinuous residues: Q130, L145, H146, L147, Q148, D151, Q154, Q242, A243, E244, N245, M246, G256, Q257
Source molecule (GenBank): NP_000567.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.5

Epitope: Epitope of Fab26A on IL1ß
Chemical type: Discontinuous protein residues
Discontinuous residues: Q130, L145, H146, L147, Q148, D151, Q154, Q242, A243, E244, N245, M246, G256, Q257
Source molecule (GenBank): NP_000567.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.645