Reference: Huan Ma; Xinghai Zhang; Peiyi Zheng; Peter H Dube; Weihong Zeng; Shaohong Chen; Qingyu Cheng; Yunru Yang; Yan Wu; Junhui Zhou; Xiaowen Hu; Yan Xiang; Huajun Zhang; Sandra Chiu; Tengchuan Jin. "Hetero-bivalent nanobodies provide broad-spectrum protection against SARS-CoV-2 variants of concern including Omicron." Cell research (2022).

Epitope: Epitope of nanobody aRBD-5 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: N448, Y449, L452, L455, F456, T470, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, G496
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00163
Host: F

Epitope: Epitope of nanobody aRBD-5 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: N448, Y449, L452, L455, F456, T470, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, G496
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 5640000.0
Host: F

Epitope: Epitope of nanobody aRBD-5 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: N448, Y449, L452, L455, F456, T470, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, G496
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0181
Host: F

Epitope: Epitope of nanobody aRBD-5 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: N448, Y449, L452, L455, F456, T470, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, G496
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 856000.0
Host: F

Epitope: Epitope of nanobody aRBD-5 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: N448, Y449, L452, L455, F456, T470, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, G496
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.8
Host: F

Epitope: Epitope of nanobody aRBD-5 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: N448, Y449, L452, L455, F456, T470, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, G496
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0143
Host: F

Epitope: Epitope of nanobody aRBD-5 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: N448, Y449, L452, L455, F456, T470, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, G496
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.3
Host: F

Epitope: Epitope of nanobody aRBD-5 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: N448, Y449, L452, L455, F456, T470, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, G496
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.21
Host: F

Epitope: Epitope of nanobody aRBD-5 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: N448, Y449, L452, L455, F456, T470, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, G496
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.9
Host: F

Epitope: Epitope of nanobody aRBD-5 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: N448, Y449, L452, L455, F456, T470, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, G496
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 6200000.0
Host: F

Epitope: Epitope of nanobody aRBD-7 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y449, G482, E484, F490, Q493, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low
Host: F

Epitope: Epitope of nanobody aRBD-7 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y449, G482, E484, F490, Q493, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.117
Host: F

Epitope: Epitope of nanobody aRBD-7 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y449, G482, E484, F490, Q493, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.141
Host: F

Epitope: Epitope of nanobody aRBD-7 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y449, G482, E484, F490, Q493, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.2
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.834
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.537
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00273
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.146
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.204
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.49
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 367000.0
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 402000.0
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0032
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000792
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 531000.0
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 567000.0
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0023
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 603000.0
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000723
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 444000.0
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00146
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 550000.0
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000656
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 545000.0
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 7.44
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 575000.0
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00848
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.4
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.88
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 7.96
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.18
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.47
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.28
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.2
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.731
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.2
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.2
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.0
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.953
Host: F

Epitope: Epitope of nanobody aRBD-2 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: D420, Y421, F456, R457, N460, Y473, Q474, A475, N487, Y489
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.238
Host: F