LiteFold/IEDB huggingface dataset:
Reference: J Zou; H Appel; M Rudwaleit; A Thiel; J Sieper. "Analysis of the CD8+ T cell response to the G1 domain of aggrecan in ankylosing spondylitis." Annals of the rheumatic diseases (2005).

Epitope: aggrecan G1 peptide 8
Chemical type: Peptide from protein
Sequence: SRVSKEKEVVLLVATEGR
Position: 76-93
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
MHC allele types: 280
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: aggrecan G1 peptide 9
Chemical type: Peptide from protein
Sequence: VVLLVATEGRVRVNSAYQ
Position: 84-101
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
MHC allele types: 280
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: aggrecan G1 peptide 16
Chemical type: Peptide from protein
Sequence: EDSEATLEVVVKGIVFHY
Position: 140-157
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Negative
MHC allele types: 280
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: aggrecan G1 peptide 16
Chemical type: Peptide from protein
Sequence: EDSEATLEVVVKGIVFHY
Position: 140-157
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
MHC allele types: 280
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: aggrecan G1 peptide 17
Chemical type: Peptide from protein
Sequence: VVVKGIVFHYRAISTRYT
Position: 148-165
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
MHC allele types: 280
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: aggrecan G1 peptide 17
Chemical type: Peptide from protein
Sequence: VVVKGIVFHYRAISTRYT
Position: 148-165
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Negative
MHC allele types: 280
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: aggrecan G1 peptide 35
Chemical type: Peptide from protein
Sequence: AGMDMCSAGWLADRSVRY
Position: 292-309
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
MHC allele types: 280
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone
Reference: M J Janusz; C B Little; L E King; E B Hookfin; K K Brown; S A Heitmeyer; B Caterson; A R Poole; Y O Taiwo. "Detection of aggrecanase- and MMP-generated catabolic neoepitopes in the rat iodoacetate model of cartilage degeneration." Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society (2004).

Epitope: AGR (387-392)
Chemical type: Peptide from protein
Sequence: NITEGE
Position: 387-392
Source molecule (GenBank): EDM08569.1
Assay category: BCell
Result: Positive

Epitope: AGR (355-360)
Chemical type: Peptide from protein
Sequence: VDIPEN
Position: 355-360
Source molecule (GenBank): EDM08569.1
Assay category: BCell
Result: Positive

Epitope: CII Alpha1(580-592)
Chemical type: Peptide from protein
Sequence: APGEDGRPGPPGP
Position: 580-592
Source molecule (GenBank): NP_001835.3
Assay category: BCell
Result: Positive

Epitope: CII Alpha1 (120-126)
Chemical type: Peptide from protein
Sequence: GPPGPQG
Position: 120-126
Source molecule (GenBank): NP_001835.3
Assay category: BCell
Result: Negative
Reference: Julien Marin; Marie-Agnès Blaton; Jean-Paul Briand; Gilles Chiocchia; Catherine Fournier; Gilles Guichard. "Synthesis of glycopeptides from type II collagen-incorporating galactosylated hydroxylysine mimetics and their use in studying the fine specificity of arthritogenic T cells." Chembiochem : a European journal of chemical biology (2005).

Epitope: mCII (256-270)
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGDQGPK
Position: 456-470
Source molecule (GenBank): P28481.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)
Reference: P Das; D S Bradley; A Geluk; M M Griffiths; H S Luthra; C S David. "An HLA-DRB1*0402 derived peptide (HV3 65-79) prevents collagen-induced arthritis in HLA-DQ8 transgenic mice." Human immunology (1999).

Epitope: DRB1*0401 (65-79)
Chemical type: Peptide from protein
Sequence: KDLLEQKRAAVDTYC
Position: 60-74
Source molecule (GenBank): AAC05182.2
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: DRB1*0401 (65-79)
Chemical type: Peptide from protein
Sequence: KDLLEQKRAAVDTYC
Position: 60-74
Source molecule (GenBank): AAC05182.2
Assay category: MhcBinding
Result: Negative

Epitope: DRB1*0404 (65-79)
Chemical type: Peptide from protein
Sequence: KDLLEQRRAAVDTYC
Position: 59-73
Source molecule (GenBank): BAA02678.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks

Epitope: DRB1*0404 (65-79)
Chemical type: Peptide from protein
Sequence: KDLLEQRRAAVDTYC
Position: 59-73
Source molecule (GenBank): BAA02678.1
Assay category: TCell
Result: Positive-Low
Host:  8-12 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: DRB1*0404 (65-79)
Chemical type: Peptide from protein
Sequence: KDLLEQRRAAVDTYC
Position: 59-73
Source molecule (GenBank): BAA02678.1
Assay category: MhcBinding
Result: Negative

Epitope: Human GAD65(250-273)
Chemical type: Peptide from protein
Sequence: AMMIARFKMFPEVKEKGMAALPRL
Position: 250-273
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive-Low
Host:  8-12 weeks

Epitope: Human GAD65(250-273)
Chemical type: Peptide from protein
Sequence: AMMIARFKMFPEVKEKGMAALPRL
Position: 250-273
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human GAD65(250-273)
Chemical type: Peptide from protein
Sequence: AMMIARFKMFPEVKEKGMAALPRL
Position: 250-273
Source molecule (GenBank): Q05329.1
Assay category: MhcBinding
Result: Positive
Reference: D B Borza; K O Netzer; A Leinonen; P Todd; J Cervera; J Saus; B G Hudson. "The goodpasture autoantigen. Identification of multiple cryptic epitopes on the NC1 domain of the alpha3(IV) collagen chain." The Journal of biological chemistry (2000).

Epitope: E<sub>A</sub>
Chemical type: Peptide from protein
Sequence: TAIPSCPEGTVPLYS
Position: 1455-1469
Source molecule (GenBank): Q01955.3
Assay category: BCell
Result: Positive

Epitope: E<sub>A</sub>
Chemical type: Peptide from protein
Sequence: TAIPSCPEGTVPLYS
Position: 1455-1469
Source molecule (GenBank): Q01955.3
Assay category: BCell
Result: Positive

Epitope: E<sub>B</sub>
Chemical type: Peptide from protein
Sequence: TDIPPCPHGWISLWK
Position: 1565-1579
Source molecule (GenBank): Q01955.3
Assay category: BCell
Result: Positive

Epitope: E<sub>B</sub>
Chemical type: Peptide from protein
Sequence: TDIPPCPHGWISLWK
Position: 1565-1579
Source molecule (GenBank): Q01955.3
Assay category: BCell
Result: Positive

Epitope: C5
Chemical type: Peptide from protein
Sequence: LMPMNMAPITGRALE
Position: 1528-1542
Source molecule (GenBank): Q01955.3
Assay category: BCell
Result: Positive

Epitope: C5
Chemical type: Peptide from protein
Sequence: LMPMNMAPITGRALE
Position: 1528-1542
Source molecule (GenBank): Q01955.3
Assay category: BCell
Result: Positive
Reference: Aki Honda; Akio Ametani; Takashi Matsumoto; Amane Iwaya; Hiroshi Kano; Satoshi Hachimura; Kensuke Ohkawa; Shucihi Kaminogawa; Koji Suzuki; Eli E Sercarz; Vipin Kumar. "Vaccination with an immunodominant peptide of bovine type II collagen induces an anti-TCR response, and modulates the onset and severity of collagen-induced arthritis." International immunology (2004).

Epitope: bCII p245-270
Chemical type: Peptide from protein
Sequence: ATGPLGPKGQTGEPGIAGFKGEQGPK
Position: 260-285
Source molecule (GenBank): P02459.3
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: bCII p245-270
Chemical type: Peptide from protein
Sequence: ATGPLGPKGQTGEPGIAGFKGEQGPK
Position: 260-285
Source molecule (GenBank): P02459.3
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: bCII p245-270
Chemical type: Peptide from protein
Sequence: ATGPLGPKGQTGEPGIAGFKGEQGPK
Position: 260-285
Source molecule (GenBank): P02459.3
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: bCII p245-270
Chemical type: Peptide from protein
Sequence: ATGPLGPKGQTGEPGIAGFKGEQGPK
Position: 260-285
Source molecule (GenBank): P02459.3
Assay category: TCell
Result: Positive
Host: F 6-8 weeks

Epitope: bCII p245-270
Chemical type: Peptide from protein
Sequence: ATGPLGPKGQTGEPGIAGFKGEQGPK
Position: 260-285
Source molecule (GenBank): P02459.3
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: bCII p316-333
Chemical type: Peptide from protein
Sequence: GFPGADGIAGPKGPAGER
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: bCII p316-333
Chemical type: Peptide from protein
Sequence: GFPGADGIAGPKGPAGER
Assay category: TCell
Result: Negative
Host: F 6-8 weeks

Epitope: B1 TCRV-beta8.2 1-30L
Chemical type: Peptide from protein
Sequence: EAAVTQSPRNKVAVTGGKVTLSCNQTNNHN
Position: 19-48
Source molecule (GenBank): E27664
Assay category: MhcBinding
Result: Negative

Epitope: B5 TCRV-beta8.2 76-101
Chemical type: Peptide from protein
Sequence: LILELATPSQTSVYFCASGDAGGGYE
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B5 TCRV-beta8.2 76-101
Chemical type: Peptide from protein
Sequence: LILELATPSQTSVYFCASGDAGGGYE
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B5 TCRV-beta8.2 76-101
Chemical type: Peptide from protein
Sequence: LILELATPSQTSVYFCASGDAGGGYE
Assay category: MhcBinding
Result: Positive
Reference: Meirav Holmdahl; Anders Grubb; Rikard Holmdahl. "Cysteine proteases in Langerhans cells limits presentation of cartilage derived type II collagen for autoreactive T cells." International immunology (2004).

Epitope: Rat CII256-270
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPK
Position: 388-402
Source molecule (GenBank): NP_037061.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 5700.0
Reference: H W Golden; C A Maniglia; G E Ranges. "A synthetic mycobacterial heat shock peptide prevents adjuvant arthritis but not proteoglycan-induced synovitis in the rat." Agents and actions (1991).

Chemical type: Peptide from protein
Sequence: TFGLQLELT
Position: 180-188
Source molecule (GenBank): P0A521.2
Assay category: TCell
Result: Positive
Host: F
Reference: L W Moreland; E E Morgan; T C Adamson; Z Fronek; L H Calabrese; J M Cash; J A Markenson; A K Matsumoto; J Bathon; E L Matteson; K M Uramoto; C M Weyand; W J Koopman; L W Heck; V Strand; J P Diveley; D J Carlo; C J Nardo; S P Richieri; S W Brostoff. "T cell receptor peptide vaccination in rheumatoid arthritis: a placebo-controlled trial using a combination of Vbeta3, Vbeta14, and Vbeta17 peptides." Arthritis and rheumatism (1998).

Epitope: IR201
Chemical type: Peptide from protein
Sequence: SQIVNDFQKGDIAEGYS
Position: 8-24
Source molecule (GenBank): AAX83266.1
Assay category: TCell
Result: Positive-Low
Host:  18-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IR203
Chemical type: Peptide from protein
Sequence: SMNVEVTDKGDVPEGYK
Position: 10-26
Source molecule (GenBank): ABO27058.1
Assay category: TCell
Result: Positive-Low
Host:  18-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IR403
Chemical type: Peptide from protein
Sequence: LGLRLIYFSYDVKMKEKGDI
Position: 63-82
Source molecule (GenBank): BAF94971.1
Assay category: TCell
Result: Positive-Low
Host:  18-70 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: J Zou; Y Zhang; A Thiel; M Rudwaleit; S-L Shi; A Radbruch; R Poole; J Braun; J Sieper. "Predominant cellular immune response to the cartilage autoantigenic G1 aggrecan in ankylosing spondylitis and rheumatoid arthritis." Rheumatology (Oxford, England) (2003).

Epitope: G1 aggrecan peptide 9
Chemical type: Peptide from protein
Sequence: VVLLVATEGRVRVNSAYQ
Position: 84-101
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: G1 aggrecan peptide 9
Chemical type: Peptide from protein
Sequence: VVLLVATEGRVRVNSAYQ
Position: 84-101
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: G1 aggrecan peptide 13
Chemical type: Peptide from protein
Sequence: ATLEVQSLRSNDSGVYRC
Position: 116-133
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: G1 aggrecan peptide 13
Chemical type: Peptide from protein
Sequence: ATLEVQSLRSNDSGVYRC
Position: 116-133
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: G1 aggrecan peptide 17
Chemical type: Peptide from protein
Sequence: VVVKGIVFHYRAISTRYT
Position: 148-165
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: G1 aggrecan peptide 17
Chemical type: Peptide from protein
Sequence: VVVKGIVFHYRAISTRYT
Position: 148-165
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: G1 aggrecan peptide 30
Chemical type: Peptide from protein
Sequence: EGEVFYATSPEKFTFQEA
Position: 252-269
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: G1 aggrecan peptide 30
Chemical type: Peptide from protein
Sequence: EGEVFYATSPEKFTFQEA
Position: 252-269
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: G1 aggrecan peptide 35
Chemical type: Peptide from protein
Sequence: AGMDMCSAGWLADRSVRY
Position: 292-309
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: G1 aggrecan peptide 35
Chemical type: Peptide from protein
Sequence: AGMDMCSAGWLADRSVRY
Position: 292-309
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: Kutty Selva Nandakumar; Johan Bäcklund; Mikael Vestberg; Rikard Holmdahl. "Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells." Arthritis research & therapy (2004).

Epitope: CII alpha 1 (256-270)
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPK
Position: 388-402
Source molecule (GenBank): P05539.2
Assay category: TCell
Result: Positive
Host: M 4-6 months
Cell type: T cell
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: CII alpha 1 (256-270)
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPK
Position: 388-402
Source molecule (GenBank): P05539.2
Assay category: TCell
Result: Negative
Host: M 4-6 months

Epitope: CII alpha 1 (256-270)
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPK
Position: 388-402
Source molecule (GenBank): P05539.2
Assay category: TCell
Result: Positive
Host: M 4-6 months
Cell type: T cell
Tissue: lymph node
Culture conditions: Cell Line / Clone
Reference: L K Myers; B Tang; E F Rosloniec; J M Stuart; T M Chiang; A H Kang. "Characterization of a peptide analog of a determinant of type II collagen that suppresses collagen-induced arthritis." Journal of immunology (Baltimore, Md. : 1950) (1998).

Epitope: A9 analog of CII (245-270)
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGQTGELGAPGNKGEQGPK
Assay category: BCell
Result: Positive-Low
Host:  8-12 weeks

Epitope: A9 analog of CII (245-270)
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGQTGELGAPGNKGEQGPK
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: A9 analog of CII (245-270)
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGQTGELGAPGNKGEQGPK
Assay category: MhcBinding
Result: Negative

Epitope: CII(245-270) A2
Chemical type: Peptide from protein
Sequence: PTGPLGPKGQTGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII(245-270) A2
Chemical type: Peptide from protein
Sequence: PTGPLGPKGQTGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII(245-270) A2
Chemical type: Peptide from protein
Sequence: PTGPLGPKGQTGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive-Low
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII(245-270) A2
Chemical type: Peptide from protein
Sequence: PTGPLGPKGQTGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive-Low
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII(245-270) A2
Chemical type: Peptide from protein
Sequence: PTGPLGPKGQTGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII(245-270) A2
Chemical type: Peptide from protein
Sequence: PTGPLGPKGQTGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII(245-270) A2
Chemical type: Peptide from protein
Sequence: PTGPLGPKGQTGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive-Low
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII(245-270) A2
Chemical type: Peptide from protein
Sequence: PTGPLGPKGQTGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII(245-270) A2
Chemical type: Peptide from protein
Sequence: PTGPLGPKGQTGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII(Y257-270)
Chemical type: Peptide from protein
Sequence: ELGIAGFKGEQGPK
Assay category: MhcBinding
Result: Positive

Epitope: A10 analog of CII (245-270)
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGQTGELGIAGFKGDTGAK
Assay category: MhcBinding
Result: Positive
Reference: S P Gartaganis; C D Georgakopoulos; M Assouti; E K Mela; A Exarchou; I Giannelou; S S Gotsis; N Ziouti; D H Vynios; B J Tripathi; R C Tripathi. "Changes in HNK-1 epitope and collagen type IX in the aqueous humour of patients with pseudoexfoliation syndrome." Current eye research (2004).

Epitope: 3-sulfoglucuronic acid
Chemical type: Other fragment
Assay category: BCell
Result: Positive
Reference: T Hellmark; H Burkhardt; J Wieslander. "Goodpasture disease. Characterization of a single conformational epitope as the target of pathogenic autoantibodies." The Journal of biological chemistry (1999).

Epitope: α3(IV)NC1 domain epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: T24, A25, I26, S28, E31, V34, P35, S38, Q64
Source molecule (GenBank): ABX71213.1
Assay category: BCell
Result: Positive
Host:  18-78 years
Reference: M C Doran; N J Goodstone; R N Hobbs; B A Ashton. "Cellular immunity to cartilage link protein in patients with inflammatory arthritis and non-arthritic controls." Annals of the rheumatic diseases (1995).

Epitope: hsp65 (180-196)
Chemical type: Peptide from protein
Sequence: TFGLQLELTEGMRFDKG
Position: 180-196
Source molecule (GenBank): P0A521.2
Assay category: TCell
Result: Negative
Host:  29-79 years
Cell type: mononuclear cell
Tissue: synovial fluid
Culture conditions: Direct Ex Vivo
Reference: Dequn Wang; Jonathan A Hill; Ewa Cairns; David A Bell. "The influence of HLA-DR4 (0401) on the immune response to type II collagen and the development of collagen induced arthritis in mice." Journal of autoimmunity (2002).

Epitope: bCII p261-273
Chemical type: Peptide from protein
Sequence: AGFKGEQGPKGEP
Position: 276-288
Source molecule (GenBank): P02459.3
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: bCII p261-273
Chemical type: Peptide from protein
Sequence: AGFKGEQGPKGEP
Position: 276-288
Source molecule (GenBank): P02459.3
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: bCII p261-273
Chemical type: Peptide from protein
Sequence: AGFKGEQGPKGEP
Position: 276-288
Source molecule (GenBank): P02459.3
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: bCII p259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 274-288
Source molecule (GenBank): P02459.3
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo
Reference: S C Yu; B Nag. "Application of murine T-T hybridoma cells to in vitro potency assay of human synthetic peptide vaccines." Vaccine (1996).

Epitope: DR4/1
Chemical type: Peptide from protein
Sequence: DAEYWNSQKDLLEQKRAAVD
Position: 57-76
Source molecule (GenBank): AAA59798.1
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell hybridoma
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: DR4/1
Chemical type: Peptide from protein
Sequence: DAEYWNSQKDLLEQKRAAVD
Position: 57-76
Source molecule (GenBank): AAA59798.1
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo
Reference: S Kerlan-Candon; P Louis-Plence; A Wiedemann; B Combe; J Clot; J F Eliaou; V Pinet. "Specific overexpression of rheumatoid arthritis-associated HLA-DR alleles and presentation of low-affinity peptides." Arthritis and rheumatism (2001).

Epitope: M1 (18-29)
Chemical type: Peptide from protein
Sequence: GPLKAEIAQRLE
Position: 18-29
Source molecule (GenBank): ABL61489.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymphoid
Culture conditions: Cell Line / Clone

Epitope: M1 (18-29)
Chemical type: Peptide from protein
Sequence: GPLKAEIAQRLE
Position: 18-29
Source molecule (GenBank): ABL61489.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1445000.0

Epitope: GLP peptide (31-49)
Chemical type: Peptide from protein
Sequence: LGQQQPFPPQQPYPQPQPF
Position: 51-69
Source molecule (GenBank): P04721.1
Assay category: MhcBinding
Result: Negative

Epitope: H3 (307-318)
Chemical type: Peptide from protein
Sequence: PKYVKQNTLKLA
Position: 306-317
Source molecule (GenBank): AAA43143.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymphoid
Culture conditions: Cell Line / Clone

Epitope: H3 (307-318)
Chemical type: Peptide from protein
Sequence: PKYVKQNTLKLA
Position: 306-317
Source molecule (GenBank): AAA43143.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 275300.0

Epitope: VK310
Chemical type: Peptide, no natural source
Sequence: PKYKKQNTLKL
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 308000.0

Epitope: NQ313
Chemical type: Peptide, no natural source
Sequence: PKYVKQQTLKLA
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 250000.0

Epitope: KR311
Chemical type: Peptide, no natural source
Sequence: PKYVRQNTLKLA
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 233600.0

Epitope: QN312
Chemical type: Peptide, no natural source
Sequence: PKYVKNNTLKLA
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 238000.0