Reference: Hannah van Dijk; Ilka Wahl; Sara Kraker; Paul M Robben; Sheetij Dutta; Hedda Wardemann. "Epitope and HLA specificity of human TCRs against Plasmodium falciparum circumsporozoite protein." The Journal of experimental medicine (2025).

Epitope: CSP61
Chemical type: Peptide from protein
Sequence: ENWYSLKKNSRSLGE
Position: 60-74
Source molecule (GenBank): Q7K740.1
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: T1
Chemical type: Peptide from protein
Sequence: PNANPNVDPNANPNV
Position: 104-118
Source molecule (GenBank): Q7K740.1
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: T*
Chemical type: Peptide from protein
Sequence: YLKKIQNSLSTEWSP
Position: 364-378
Source molecule (GenBank): P08307.1
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: T*
Chemical type: Peptide from protein
Sequence: YLKKIQNSLSTEWSP
Position: 364-378
Source molecule (GenBank): P08307.1
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: CSP81
Chemical type: Peptide from protein
Sequence: NEDNEKLRKPKHKKL
Position: 80-94
Source molecule (GenBank): Q7K740.1
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: Th2R
Chemical type: Peptide from protein
Sequence: HIEQYLKKIQNSLST
Position: 360-374
Source molecule (GenBank): P08307.1
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: Th2R
Chemical type: Peptide from protein
Sequence: HIEQYLKKIQNSLST
Position: 360-374
Source molecule (GenBank): P08307.1
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: CSP65-73
Chemical type: Peptide from protein
Sequence: SLKKNSRSL
Position: 64-72
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP65-73
Chemical type: Peptide from protein
Sequence: SLKKNSRSL
Position: 64-72
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: CSP65-73
Chemical type: Peptide from protein
Sequence: SLKKNSRSL
Position: 64-72
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP65-73
Chemical type: Peptide from protein
Sequence: SLKKNSRSL
Position: 64-72
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive

Epitope: CSP65-73
Chemical type: Peptide from protein
Sequence: SLKKNSRSL
Position: 64-72
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive

Epitope: CSP86-94
Chemical type: Peptide from protein
Sequence: LRKPKHKKL
Position: 86-94
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP86-94
Chemical type: Peptide from protein
Sequence: LRKPKHKKL
Position: 86-94
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP86-94
Chemical type: Peptide from protein
Sequence: LRKPKHKKL
Position: 86-94
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP86-94
Chemical type: Peptide from protein
Sequence: LRKPKHKKL
Position: 86-94
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP86-94
Chemical type: Peptide from protein
Sequence: LRKPKHKKL
Position: 86-94
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: CSP285-293
Chemical type: Peptide from protein
Sequence: MPNDPNRNV
Position: 285-293
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP285-293
Chemical type: Peptide from protein
Sequence: MPNDPNRNV
Position: 285-293
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP285-293
Chemical type: Peptide from protein
Sequence: MPNDPNRNV
Position: 285-293
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP285-293
Chemical type: Peptide from protein
Sequence: MPNDPNRNV
Position: 285-293
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive

Epitope: CSP285-293
Chemical type: Peptide from protein
Sequence: MPNDPNRNV
Position: 285-293
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP319-327
Chemical type: Peptide from protein
Sequence: YLNKIQNSL
Position: 319-327
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP319-327
Chemical type: Peptide from protein
Sequence: YLNKIQNSL
Position: 319-327
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive

Epitope: CSP319-327
Chemical type: Peptide from protein
Sequence: YLNKIQNSL
Position: 319-327
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP319-327
Chemical type: Peptide from protein
Sequence: YLNKIQNSL
Position: 319-327
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive

Epitope: CSP319-327
Chemical type: Peptide from protein
Sequence: YLNKIQNSL
Position: 319-327
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive

Epitope: CSP310-319
Chemical type: Peptide from protein
Sequence: EPSDKHIKEY
Position: 310-319
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: CSP310-319
Chemical type: Peptide from protein
Sequence: EPSDKHIKEY
Position: 310-319
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP310-319
Chemical type: Peptide from protein
Sequence: EPSDKHIKEY
Position: 310-319
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP310-319
Chemical type: Peptide from protein
Sequence: EPSDKHIKEY
Position: 310-319
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: CSP310-319
Chemical type: Peptide from protein
Sequence: EPSDKHIKEY
Position: 310-319
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: CSP336-345
Chemical type: Peptide from protein
Sequence: VTCGNGIQVR
Position: 336-345
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP336-345
Chemical type: Peptide from protein
Sequence: VTCGNGIQVR
Position: 336-345
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP336-345
Chemical type: Peptide from protein
Sequence: VTCGNGIQVR
Position: 336-345
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: CSP336-345
Chemical type: Peptide from protein
Sequence: VTCGNGIQVR
Position: 336-345
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: CSP336-345
Chemical type: Peptide from protein
Sequence: VTCGNGIQVR
Position: 336-345
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: CSP353-360
Chemical type: Peptide from protein
Sequence: KPKDELDY
Position: 353-360
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP353-360
Chemical type: Peptide from protein
Sequence: KPKDELDY
Position: 353-360
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive

Epitope: CSP353-360
Chemical type: Peptide from protein
Sequence: KPKDELDY
Position: 353-360
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Negative

Epitope: CSP353-360
Chemical type: Peptide from protein
Sequence: KPKDELDY
Position: 353-360
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: CSP353-360
Chemical type: Peptide from protein
Sequence: KPKDELDY
Position: 353-360
Source molecule (GenBank): Q7K740.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: MEKCSSVFNVV
Chemical type: Peptide from protein
Sequence: MEKCSSVFNVV
Position: 371-381
Source molecule (GenBank): Q7K740.1
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered