Reference: Hengrui Hu; Chao Leng; Yanni Shu; Lu Peng; Fan Wu; Jia Liu; Xiaolu Zhang; Wei Zhou; Qinghong Xiao; Yufeng Li; Bihao Wu; Jiamei Shen; Jiang Li; Rui Gong; Bing Yan; Fei Deng; Zhihong Hu; Sheng Cao; Manli Wang. "Structural insights into hybridoma-derived neutralizing monoclonal antibodies against Omicron BA.5 and XBB.1.16 variants of SARS-CoV-2." Journal of virology (2025).

Epitope: Epitope of mAb ORB10 on Omicron BA.5 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R398, G399, N400, E401, Q404, T410, G411, N412, D415, Y416, V440, G441, Y444, Y448, L450, F451, Y484, R493, T495, Y496, G497, V498, G499, H500
Source molecule (GenBank): UUB67338.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb ORB10 on Omicron BA.5 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R398, G399, N400, E401, Q404, T410, G411, N412, D415, Y416, V440, G441, Y444, Y448, L450, F451, Y484, R493, T495, Y496, G497, V498, G499, H500
Source molecule (GenBank): UUB67338.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb ORB10 on Omicron BA.5 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R398, G399, N400, E401, Q404, T410, G411, N412, D415, Y416, V440, G441, Y444, Y448, L450, F451, Y484, R493, T495, Y496, G497, V498, G499, H500
Source molecule (GenBank): UUB67338.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb ORB10 on Omicron BA.5 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R398, G399, N400, E401, Q404, T410, G411, N412, D415, Y416, V440, G441, Y444, Y448, L450, F451, Y484, R493, T495, Y496, G497, V498, G499, H500
Source molecule (GenBank): UUB67338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00000263

Epitope: Epitope of mAb ORB10 on Omicron BA.5 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R398, G399, N400, E401, Q404, T410, G411, N412, D415, Y416, V440, G441, Y444, Y448, L450, F451, Y484, R493, T495, Y496, G497, V498, G499, H500
Source molecule (GenBank): UUB67338.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb ORB10 on Omicron BA.5 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R398, G399, N400, E401, Q404, T410, G411, N412, D415, Y416, V440, G441, Y444, Y448, L450, F451, Y484, R493, T495, Y496, G497, V498, G499, H500
Source molecule (GenBank): UUB67338.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of mAb ORB10 on Omicron BA.5 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R398, G399, N400, E401, Q404, T410, G411, N412, D415, Y416, V440, G441, Y444, Y448, L450, F451, Y484, R493, T495, Y496, G497, V498, G499, H500
Source molecule (GenBank): UUB67338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0107

Epitope: Epitope of mAb ORB10 on Omicron BA.5 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R398, G399, N400, E401, Q404, T410, G411, N412, D415, Y416, V440, G441, Y444, Y448, L450, F451, Y484, R493, T495, Y496, G497, V498, G499, H500
Source molecule (GenBank): UUB67338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 246000.0

Epitope: Epitope of mAb ORB10 on Omicron BA.5 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R398, G399, N400, E401, Q404, T410, G411, N412, D415, Y416, V440, G441, Y444, Y448, L450, F451, Y484, R493, T495, Y496, G497, V498, G499, H500
Source molecule (GenBank): UUB67338.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of mAb ORB10 on Omicron BA.5 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R398, G399, N400, E401, Q404, T410, G411, N412, D415, Y416, V440, G441, Y444, Y448, L450, F451, Y484, R493, T495, Y496, G497, V498, G499, H500
Source molecule (GenBank): UUB67338.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb ORB10 on Omicron BA.5 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R398, G399, N400, E401, Q404, T410, G411, N412, D415, Y416, V440, G441, Y444, Y448, L450, F451, Y484, R493, T495, Y496, G497, V498, G499, H500
Source molecule (GenBank): UUB67338.1
Assay category: BCell
Result: Positive-Intermediate