Reference: D J Hankey; J M Nickerson; L A Donoso; S L Lightman; D Baker. "Experimental autoimmune uveoretinitis in mice (Biozzi ABH and NOD) expressing the autoimmune-associated H-2A(g7) molecule: identification of a uveitogenic epitope." Journal of neuroimmunology (2001).

Epitope: IRBP 461-480
Chemical type: Peptide from protein
Sequence: LRHNPGGPSSAVPLLLSYFQ
Position: 478-497
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 461-480
Chemical type: Peptide from protein
Sequence: LRHNPGGPSSAVPLLLSYFQ
Position: 478-497
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks

Epitope: IRBP 481-500
Chemical type: Peptide from protein
Sequence: GPEAGPVHLFTTYDRRTNIT
Position: 498-517
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 481-500
Chemical type: Peptide from protein
Sequence: GPEAGPVHLFTTYDRRTNIT
Position: 498-517
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks

Epitope: IRBP 491-510
Chemical type: Peptide from protein
Sequence: TTYDRRTNITQEHFSHMELP
Position: 508-527
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 491-510
Chemical type: Peptide from protein
Sequence: TTYDRRTNITQEHFSHMELP
Position: 508-527
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks

Epitope: IRBP 501-520
Chemical type: Peptide from protein
Sequence: QEHFSHMELPGPRYSTQRGV
Position: 518-537
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 501-520
Chemical type: Peptide from protein
Sequence: QEHFSHMELPGPRYSTQRGV
Position: 518-537
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks

Epitope: IRBP 511-530
Chemical type: Peptide from protein
Sequence: GPRYSTQRGVYLLTSHRTAT
Position: 528-547
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 511-530
Chemical type: Peptide from protein
Sequence: GPRYSTQRGVYLLTSHRTAT
Position: 528-547
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 511-530
Chemical type: Peptide from protein
Sequence: GPRYSTQRGVYLLTSHRTAT
Position: 528-547
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 511-530
Chemical type: Peptide from protein
Sequence: GPRYSTQRGVYLLTSHRTAT
Position: 528-547
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 511-530
Chemical type: Peptide from protein
Sequence: GPRYSTQRGVYLLTSHRTAT
Position: 528-547
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks

Epitope: IRBP 521-540
Chemical type: Peptide from protein
Sequence: YLLTSHRTATAAEEFAFLMQ
Position: 538-557
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 521-540
Chemical type: Peptide from protein
Sequence: YLLTSHRTATAAEEFAFLMQ
Position: 538-557
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks

Epitope: IRBP 541-560
Chemical type: Peptide from protein
Sequence: SLGWATLVGEITAGNLLHTR
Position: 558-577
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 541-560
Chemical type: Peptide from protein
Sequence: SLGWATLVGEITAGNLLHTR
Position: 558-577
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks

Epitope: IRBP 551-570
Chemical type: Peptide from protein
Sequence: ITAGNLLHTRTVPLLDTPEG
Position: 568-587
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 561-580
Chemical type: Peptide from protein
Sequence: TVPLLDTPEGSLALTVPVLT
Position: 578-597
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 571-590
Chemical type: Peptide from protein
Sequence: SLALTVPVLTFIDNHGEAWL
Position: 588-607
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 571-590
Chemical type: Peptide from protein
Sequence: SLALTVPVLTFIDNHGEAWL
Position: 588-607
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 571-590
Chemical type: Peptide from protein
Sequence: SLALTVPVLTFIDNHGEAWL
Position: 588-607
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 571-590
Chemical type: Peptide from protein
Sequence: SLALTVPVLTFIDNHGEAWL
Position: 588-607
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 591-610
Chemical type: Peptide from protein
Sequence: GGGVVPDAIVLAEEALDKAQ
Position: 608-627
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 601-620
Chemical type: Peptide from protein
Sequence: LAEEALDKAQEVLEFHQSLG
Position: 618-637
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 611-630
Chemical type: Peptide from protein
Sequence: EVLEFHQSLGALVEGTGHLL
Position: 628-647
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 611-630
Chemical type: Peptide from protein
Sequence: EVLEFHQSLGALVEGTGHLL
Position: 628-647
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 611-630
Chemical type: Peptide from protein
Sequence: EVLEFHQSLGALVEGTGHLL
Position: 628-647
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 611-630
Chemical type: Peptide from protein
Sequence: EVLEFHQSLGALVEGTGHLL
Position: 628-647
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 301-320
Chemical type: Peptide from protein
Sequence: AILTLRSALPGVVHCLQEVL
Position: 318-337
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 291-310
Chemical type: Peptide from protein
Sequence: PAEQALEKALAILTLRSALP
Position: 308-327
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 311-330
Chemical type: Peptide from protein
Sequence: GVVHCLQEVLKDYYTLVDRV
Position: 328-347
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 311-330
Chemical type: Peptide from protein
Sequence: GVVHCLQEVLKDYYTLVDRV
Position: 328-347
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 311-330
Chemical type: Peptide from protein
Sequence: GVVHCLQEVLKDYYTLVDRV
Position: 328-347
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 311-330
Chemical type: Peptide from protein
Sequence: GVVHCLQEVLKDYYTLVDRV
Position: 328-347
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 331-350
Chemical type: Peptide from protein
Sequence: PTLLQHLASMDFSTVVSEED
Position: 348-367
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 341-360
Chemical type: Peptide from protein
Sequence: DFSTVVSEEDLVTKLNAGLQ
Position: 358-377
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 361-380
Chemical type: Peptide from protein
Sequence: AASEDPRLLVRAIGPTETPS
Position: 378-397
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 371-390
Chemical type: Peptide from protein
Sequence: RAIGPTETPSWPAPDAAAED
Position: 388-407
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 381-400
Chemical type: Peptide from protein
Sequence: WPAPDAAAEDSPGVAPELPE
Position: 398-417
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 391-410
Chemical type: Peptide from protein
Sequence: SPGVAPELPEDEAIRQALVDS
Position: 408-428
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 401-420
Chemical type: Peptide from protein
Sequence: DEAIRQALVDSVFQVSVLPG
Position: 418-437
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 431-450
Chemical type: Peptide from protein
Sequence: ADASVLGVLAPYVLRQVREP
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 441-460
Chemical type: Peptide from protein
Sequence: PYVLRQVREPLQDTEHLIMD
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 451-470
Chemical type: Peptide from protein
Sequence: LQDTEHLIMDLRHNPGGPSS
Position: 468-487
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IRBP 161-180
Chemical type: Peptide from protein
Sequence: SGIPYIISYLHPGNTILHVD
Position: 178-197
Source molecule (GenBank): AAH39844.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks