Reference: Niannian Ji; Animesh Somanaboeina; Aakanksha Dixit; Kazuyuki Kawamura; Neil J Hayward; Christopher Self; Gary L Olson; Thomas G Forsthuber. "Small molecule inhibitor of antigen binding and presentation by HLA-DR2b as a therapeutic strategy for the treatment of multiple sclerosis." Journal of immunology (Baltimore, Md. : 1950) (2013).

Epitope: MBP85-99
Chemical type: Peptide from protein
Sequence: ENPVVHFFKNIVTPR
Position: 217-231
Source molecule (GenBank): P02686.3
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 5.0

Epitope: MBP89-95 (Compound 1)
Chemical type: Peptide from protein
Sequence: VHFFKNI
Position: 221-227
Source molecule (GenBank): P02686.3
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1213.0

Epitope: Compound 2
Chemical type: Peptide, no natural source
Sequence: VRFFKNI
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 707.0

Epitope: Compounds 3 and 4
Chemical type: Peptide, no natural source
Sequence: GRFFKNI
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 4.0

Epitope: Compounds 5 and 6
Chemical type: Peptide, no natural source
Sequence: VRFFKNI
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 17.0

Epitope: Compound 7
Chemical type: Peptide, no natural source
Sequence: VVHFKNI
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 52.0

Epitope: Compound 8
Chemical type: Peptide, no natural source
Sequence: VGRFFK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 3.0

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.0

Epitope: PV-267
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 862.0

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive-Low
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive-Low
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive-Low
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MBP87-99
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTP
Position: 221-233
Source molecule (GenBank): P02686.3
Assay category: TCell
Result: Positive-Low
Host: M 56 years
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Influenza A matrix protein peptide 17-31
Chemical type: Peptide from protein
Sequence: SGPLKAEIAQRLEDV
Position: 17-31
Source molecule (GenBank): ACF41835.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Tetanus toxin peptide 830-843
Chemical type: Peptide from protein
Sequence: QYIKANSKFIGITE
Position: 830-843
Source molecule (GenBank): P04958.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Influenza hemagglutinin peptide 307-319
Chemical type: Peptide from protein
Sequence: PKYVKQNTLKLAT
Position: 322-334
Source molecule (GenBank): P03438.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Tetanus toxin peptide 830-844
Chemical type: Peptide from protein
Sequence: QYIKANSKFIGITEL
Position: 830-844
Source molecule (GenBank): P04958.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MOG35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 63-83
Source molecule (GenBank): Q61885.1
Assay category: BCell
Result: Positive

Epitope: MOG35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 63-83
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive

Epitope: MOG35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 63-83
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive

Epitope: MOG35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 63-83
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive

Epitope: MOG35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 63-83
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive