Reference: Abdullah A Al-Omari; Katherine W Cook; Peter Symonds; Anne Skinner; Alissa Wright; Yaling Zhu; Vincent L Coble; Omar J Mohammed; Ruhul H Choudhury; Nazim Uddin; Priscilla Ranglani; Adrian Parry; Sally E Adams; Geoffrey M Lynn; Lindy G Durrant; Victoria A Brentville. "Modi-2 a vaccine stimulating CD4 responses to homocitrullinated self epitopes as therapy for solid cancers." NPJ vaccines (2024).

Epitope: Aldo 74-93 wt
Chemical type: Peptide from protein
Sequence: IGGVILFHETLYQKADDGRP
Position: 74-93
Source molecule (GenBank): P04075.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Aldo 74-93 wt
Chemical type: Peptide from protein
Sequence: IGGVILFHETLYQKADDGRP
Position: 74-93
Source molecule (GenBank): P04075.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Bip 562-579 wt
Chemical type: Peptide from protein
Sequence: RNELESYAYSLKNQIGDK
Position: 562-579
Source molecule (GenBank): P11021.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Bip 562-579 wt
Chemical type: Peptide from protein
Sequence: RNELESYAYSLKNQIGDK
Position: 562-579
Source molecule (GenBank): P11021.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: BiP 562-579hcit
Chemical type: Peptide, no natural source
Sequence: RNELESYAYSLKNQIGDK
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: BiP 562-579hcit
Chemical type: Peptide, no natural source
Sequence: RNELESYAYSLKNQIGDK
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: BiP 562-579hcit
Chemical type: Peptide, no natural source
Sequence: RNELESYAYSLKNQIGDK
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: BiP 562-579hcit
Chemical type: Peptide, no natural source
Sequence: RNELESYAYSLKNQIGDK
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 371-388 wt
Chemical type: Peptide from protein
Sequence: LREYQELMNVKLALDIEI
Position: 371-388
Source molecule (GenBank): P05787.7
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 371-388 wt
Chemical type: Peptide from protein
Sequence: LREYQELMNVKLALDIEI
Position: 371-388
Source molecule (GenBank): P05787.7
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 371-388hcit
Chemical type: Peptide, no natural source
Sequence: LREYQELMNVKLALDIEI
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 371-388hcit
Chemical type: Peptide, no natural source
Sequence: LREYQELMNVKLALDIEI
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 371-388hcit
Chemical type: Peptide, no natural source
Sequence: LREYQELMNVKLALDIEI
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 371-388hcit
Chemical type: Peptide, no natural source
Sequence: LREYQELMNVKLALDIEI
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 116-135hcit
Chemical type: Peptide, no natural source
Sequence: NYIDKVRFLEQQNKILLAEL
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 116-135hcit
Chemical type: Peptide, no natural source
Sequence: NYIDKVRFLEQQNKILLAEL
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 116-135hcit
Chemical type: Peptide, no natural source
Sequence: NYIDKVRFLEQQNKILLAEL
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 116-135hcit
Chemical type: Peptide, no natural source
Sequence: NYIDKVRFLEQQNKILLAEL
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: carbamylation (homocitrulline)
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive

Epitope: carbamylation (homocitrulline)
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive

Epitope: carbamylation (homocitrulline)
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive

Epitope: carbamylation (homocitrulline)
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive

Epitope: carbamylation (homocitrulline)
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive