Reference: Lijin Li; Xiuli Zhang; Xiaoli Wang; Samuel W Kim; John M Herndon; Michelle K Becker-Hapak; Beatriz M Carreno; Nancy B Myers; Mark A Sturmoski; Michael D McLellan; Christopher A Miller; Tanner M Johanns; Benjamin R Tan; Gavin P Dunn; Timothy P Fleming; Ted H Hansen; S Peter Goedegebuure; William E Gillanders. "Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation." Genome medicine (2021).

Epitope: Tmem101.G96V
Chemical type: Peptide, no natural source
Sequence: STYTAYIV
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Tmem101.G96V
Chemical type: Peptide, no natural source
Sequence: STYTAYIV
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Tmem101.G96V
Chemical type: Peptide, no natural source
Sequence: STYTAYIV
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Pank3.G321W
Chemical type: Peptide, no natural source
Sequence: FVWNFLRV
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Pank3.G321W
Chemical type: Peptide, no natural source
Sequence: FVWNFLRV
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Pank3.G321W
Chemical type: Peptide, no natural source
Sequence: FVWNFLRV
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Plekho1.P251S
Chemical type: Peptide, no natural source
Sequence: ASYTPQAL
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Plekho1.P251S
Chemical type: Peptide, no natural source
Sequence: ASYTPQAL
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Plekho1.P251S
Chemical type: Peptide, no natural source
Sequence: ASYTPQAL
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Plekho1.P251S
Chemical type: Peptide, no natural source
Sequence: ASYTPQAL
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Exoc4.E901V
Chemical type: Peptide, no natural source
Sequence: VMLYNTADEL
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Exoc4.E901V
Chemical type: Peptide, no natural source
Sequence: VMLYNTADEL
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Exoc4.E901V
Chemical type: Peptide, no natural source
Sequence: VMLYNTADEL
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Lrrc27.G330A
Chemical type: Peptide, no natural source
Sequence: SAYQNTVHA
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Lrrc27.G330A
Chemical type: Peptide, no natural source
Sequence: SAYQNTVHA
Assay category: TCell
Result: Positive
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: Lrrc27.G330A
Chemical type: Peptide, no natural source
Sequence: SAYQNTVHA
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Lrrc27.G330A
Chemical type: Peptide, no natural source
Sequence: SAYQNTVHA
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Lrrc27.G330A
Chemical type: Peptide, no natural source
Sequence: SAYQNTVHA
Assay category: TCell
Result: Negative
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: Lrrc27.G330A
Chemical type: Peptide, no natural source
Sequence: SAYQNTVHA
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Xpo4.V611L
Chemical type: Peptide, no natural source
Sequence: VIRLLSAL
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Xpo4.V611L
Chemical type: Peptide, no natural source
Sequence: VIRLLSAL
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Xpo4.V611L
Chemical type: Peptide, no natural source
Sequence: VIRLLSAL
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Xpo4.V611L
Chemical type: Peptide, no natural source
Sequence: VIRLLSAL
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Pttg1.V53L
Chemical type: Peptide, no natural source
Sequence: KVFNAPAL
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Pttg1.V53L
Chemical type: Peptide, no natural source
Sequence: KVFNAPAL
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Pttg1.V53L
Chemical type: Peptide, no natural source
Sequence: KVFNAPAL
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Pttg1.V53L
Chemical type: Peptide, no natural source
Sequence: KVFNAPAL
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Neil3.P90H
Chemical type: Peptide, no natural source
Sequence: MYFGHRAL
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Hist1h3e.H114N
Chemical type: Peptide, no natural source
Sequence: INAKRVTIM
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Prkag1.R268L
Chemical type: Peptide, no natural source
Sequence: LSHYFEGVL
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: BC057079.V1474M
Chemical type: Peptide, no natural source
Sequence: SMPLWAKHM
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Met.I851M
Chemical type: Peptide, no natural source
Sequence: MGNENVVEI
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Map3k6.T552A
Chemical type: Peptide, no natural source
Sequence: VSAVTLSLL
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Aars2.A697P
Chemical type: Peptide, no natural source
Sequence: VGQDKPVFMEEVPLPHTARIPGLRSLDEV
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Aars2.A697P
Chemical type: Peptide, no natural source
Sequence: VGQDKPVFMEEVPLPHTARIPGLRSLDEV
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Dync1h1.Y3123C
Chemical type: Peptide, no natural source
Sequence: SKMDLEKPNYIVPDCMPVVYDKLPQPPTH
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Dtx2.P365L
Chemical type: Peptide, no natural source
Sequence: LSRAPRPTGPPASRLASKSHSSVKRLRKM
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Pram1.Q572L
Chemical type: Peptide, no natural source
Sequence: QPQQLPATDPKLLKLIRKAEKAEREFRKK
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Pram1.Q572L
Chemical type: Peptide, no natural source
Sequence: QPQQLPATDPKLLKLIRKAEKAEREFRKK
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Gyk.K505R
Chemical type: Peptide, no natural source
Sequence: INAEESEIRYSTWKRAVMKSIGWVTTQSP
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Gyk.K505R
Chemical type: Peptide, no natural source
Sequence: INAEESEIRYSTWKRAVMKSIGWVTTQSP
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Gprc5a.F119L
Chemical type: Peptide, no natural source
Sequence: FAICFSCLLAHALNLIKLVRGRKPLSW
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Zfp142.R1119C
Chemical type: Peptide, no natural source
Sequence: EGCRGGRGQKRKRGCPQTHAVVLPLNNGD
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Dhx58.R654L
Chemical type: Peptide, no natural source
Sequence: LETPRGKIQAKKWSLVPFSIPVFDILQDC
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Isoc2a.S195G
Chemical type: Peptide, no natural source
Sequence: FKEIQKIIKEPVPDSGLLGLFQGQSPLTS
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Gen1.K707N
Chemical type: Peptide, no natural source
Sequence: IPHNPRVAVKTTNNLVMKNSVCLERDS
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Gpld1.R829W
Chemical type: Peptide, no natural source
Sequence: GRNQVVVAAGRSSWGAWLSGALHVYSFSS
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Gpld1.R829W
Chemical type: Peptide, no natural source
Sequence: GRNQVVVAAGRSSWGAWLSGALHVYSFSS
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Igsf9.S813R
Chemical type: Peptide, no natural source
Sequence: DSVTKFKLQGSPVPRLRQSLLWGEPARP
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Lta4h.V420I
Chemical type: Peptide, no natural source
Sequence: GFLKAYVKKFSYQSITTDDWKSFLYSHFK
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Qars.E530D
Chemical type: Peptide, no natural source
Sequence: FTLTALRRRGFPPDAINNFCARVGVTV
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Plekho1 wt
Chemical type: Peptide from protein
Sequence: APYTPQAL
Position: 250-257
Source molecule (GenBank): NP_075809.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Pttg1 wt
Chemical type: Peptide from protein
Sequence: KVFNAPAV
Position: 46-53
Source molecule (GenBank): AAZ83265.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Lrrc27 wt
Chemical type: Peptide from protein
Sequence: SGYQNTVHA
Position: 329-337
Source molecule (GenBank): NP_081440.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PDIA5:p.H416R
Chemical type: Peptide, no natural source
Sequence: GDNFRETLKKKKRTLVMFYAPWCPH
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TBC1D22A:p.R437S
Chemical type: Peptide, no natural source
Sequence: LLMREVPLRCTISLWDTYQSEPDGF
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TBC1D22A:p.R437S
Chemical type: Peptide, no natural source
Sequence: LLMREVPLRCTISLWDTYQSEPDGF
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GZF1:p.G253C
Chemical type: Peptide, no natural source
Sequence: TRRLREQQKTAECDVGDYRCPQDQS
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TRPC4AP:p.T63M
Chemical type: Peptide, no natural source
Sequence: LVRAVQFTETFLMERDKQSKWSGIP
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TRPC4AP:p.T63M
Chemical type: Peptide, no natural source
Sequence: LVRAVQFTETFLMERDKQSKWSGIP
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PCGF2:p.D128G
Chemical type: Peptide, no natural source
Sequence: EVLEQEKGALSDGEIVSLSIEFYEG
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SIPA1L3:p.T687A
Chemical type: Peptide, no natural source
Sequence: VKTDSTGTHSLYAMYQDYEIMFHVS
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TBC1D20:p.A390T
Chemical type: Peptide, no natural source
Sequence: ALGAAALAVVKSTLEWAPKFQLQLF
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SDHA:p.H407R
Chemical type: Peptide, no natural source
Sequence: VTKEPIPVLPTVRYNMGGIPTNYKG
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CCDC6:p.R216H
Chemical type: Peptide, no natural source
Sequence: NTLEQEQEALVNHLWKRMDKLEAEK
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LAMA5:p.R1026W
Chemical type: Peptide, no natural source
Sequence: PSAYYEAALLQLWVTEACTYRPSAQ
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SACS:p.S2711L
Chemical type: Peptide, no natural source
Sequence: RFPLRNAEMAKVLEISSVPASDRMV
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ZNF611:p.D404G
Chemical type: Peptide, no natural source
Sequence: HTGEKPYRCKVCGTAFTWHSQLARH
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ZNF611:p.D404G
Chemical type: Peptide, no natural source
Sequence: HTGEKPYRCKVCGTAFTWHSQLARH
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated