Reference: James F Mohan; Shirley J Petzold; Emil R Unanue. "Register shifting of an insulin peptide-MHC complex allows diabetogenic T cells to escape thymic deletion." The Journal of experimental medicine (2011).

Epitope: Ins B:13-21
Chemical type: Peptide from protein
Sequence: EALYLVCGE
Position: 37-45
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Ins B:13-21
Chemical type: Peptide from protein
Sequence: EALYLVCGE
Position: 37-45
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Ins B:13-21
Chemical type: Peptide from protein
Sequence: EALYLVCGE
Position: 37-45
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Ins B:13-21
Chemical type: Peptide from protein
Sequence: EALYLVCGE
Position: 37-45
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Ins B:13-21
Chemical type: Peptide from protein
Sequence: EALYLVCGE
Position: 37-45
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: Ins B:13-21
Chemical type: Peptide from protein
Sequence: EALYLVCGE
Position: 37-45
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: Ins B:13-21
Chemical type: Peptide from protein
Sequence: EALYLVCGE
Position: 37-45
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Ins B:13-21
Chemical type: Peptide from protein
Sequence: EALYLVCGE
Position: 37-45
Source molecule (GenBank): P01326.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 5900.0

Epitope: Ins B:9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Ins B:9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Ins B:9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01326.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1500.0

Epitope: Nested B:12–20
Chemical type: Peptide, no natural source
Sequence: TEGVEALYLVCGGGS
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1400.0

Epitope: Nested B:12–20 K20
Chemical type: Peptide, no natural source
Sequence: TEGVEALYLVC KGGS
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1600.0

Epitope: Nested B:13–21
Chemical type: Peptide, no natural source
Sequence: TEGEALYLVCGEGGS
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 700.0

Epitope: Nested B:13–21 K21
Chemical type: Peptide, no natural source
Sequence: TEGEALYLVCGKGGS
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: Nested B:14–22
Chemical type: Peptide, no natural source
Sequence: TEGALYLVCGERGGS
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 5500.0

Epitope: Nested B:12–21
Chemical type: Peptide, no natural source
Sequence: GTEVEALYLVCGEGGS
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 500.0

Epitope: Nested B:12–22
Chemical type: Peptide, no natural source
Sequence: TEGVEALYLVCGERGGS
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 900.0