Reference: Tomohiko Murase; Luiz Eugenio; Melissa Schorr; Greg Hussack; Jamshid Tanha; Elena N Kitova; John S Klassen; Kenneth K S Ng. "Structural basis for antibody recognition in the receptor-binding domains of toxins A and B from Clostridium difficile." The Journal of biological chemistry (2014).

Epitope: Epitope 1 of A20.1 VHH on C. difficile TcdA-A1
Chemical type: Discontinuous protein residues
Discontinuous residues: I152, Y163, P166, N168, T169, R184, F185, H187, L188, L189, Y213, V239
Source molecule (GenBank): WP_003423571.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope 1 of A20.1 VHH on C. difficile TcdA-A1
Chemical type: Discontinuous protein residues
Discontinuous residues: I152, Y163, P166, N168, T169, R184, F185, H187, L188, L189, Y213, V239
Source molecule (GenBank): WP_003423571.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.75
Host: M

Epitope: Epitope 1 of A20.1 VHH on C. difficile TcdA-A1
Chemical type: Discontinuous protein residues
Discontinuous residues: I152, Y163, P166, N168, T169, R184, F185, H187, L188, L189, Y213, V239
Source molecule (GenBank): WP_003423571.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope 1 of A20.1 VHH on C. difficile TcdA-A1
Chemical type: Discontinuous protein residues
Discontinuous residues: I152, Y163, P166, N168, T169, R184, F185, H187, L188, L189, Y213, V239
Source molecule (GenBank): WP_003423571.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.08
Host: M

Epitope: Epitope 2 of A20.1 VHH on C. difficile TcdA
Chemical type: Discontinuous protein residues
Discontinuous residues: I61, Y72, P75, A76, N77, T78, Y90, R93, F94, Y96, L97, H98, D99
Source molecule (GenBank): WP_003423571.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope 2 of A20.1 VHH on C. difficile TcdA
Chemical type: Discontinuous protein residues
Discontinuous residues: I61, Y72, P75, A76, N77, T78, Y90, R93, F94, Y96, L97, H98, D99
Source molecule (GenBank): WP_003423571.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope 2 of A20.1 VHH on C. difficile TcdA
Chemical type: Discontinuous protein residues
Discontinuous residues: I61, Y72, P75, A76, N77, T78, Y90, R93, F94, Y96, L97, H98, D99
Source molecule (GenBank): WP_003423571.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.61
Host: M

Epitope: Epitope 2 of A20.1 VHH on C. difficile TcdA
Chemical type: Discontinuous protein residues
Discontinuous residues: I61, Y72, P75, A76, N77, T78, Y90, R93, F94, Y96, L97, H98, D99
Source molecule (GenBank): WP_003423571.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.08
Host: M

Epitope: Epitope 3 of A26.8 VHH on C. difficile TcdA
Chemical type: Discontinuous protein residues
Discontinuous residues: G225, G226, L227, F228, E229, G232, V233, I234, F236
Source molecule (GenBank): WP_003423571.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope 3 of A26.8 VHH on C. difficile TcdA
Chemical type: Discontinuous protein residues
Discontinuous residues: G225, G226, L227, F228, E229, G232, V233, I234, F236
Source molecule (GenBank): WP_003423571.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope 3 of A26.8 VHH on C. difficile TcdA
Chemical type: Discontinuous protein residues
Discontinuous residues: G225, G226, L227, F228, E229, G232, V233, I234, F236
Source molecule (GenBank): WP_003423571.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.3
Host: M

Epitope: Epitope 3 of A26.8 VHH on C. difficile TcdA
Chemical type: Discontinuous protein residues
Discontinuous residues: G225, G226, L227, F228, E229, G232, V233, I234, F236
Source molecule (GenBank): WP_003423571.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.61
Host: M

Epitope: Epitope 3 of A26.8 VHH on C. difficile TcdA
Chemical type: Discontinuous protein residues
Discontinuous residues: G225, G226, L227, F228, E229, G232, V233, I234, F236
Source molecule (GenBank): WP_003423571.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.75
Host: M

Epitope: Epitope 4 of B39 VHH on C. difficile TcdB-B1
Chemical type: Discontinuous protein residues
Discontinuous residues: L2255, I2256, S2257, N2262, Y2263, I2278, E2279, K2281, F2283, F2285, M2291, Q2308, D2312, E2313, N2314, F2315, E2316
Source molecule (GenBank): P18177.3
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope 4 of B39 VHH on C. difficile TcdB-B1
Chemical type: Discontinuous protein residues
Discontinuous residues: L2255, I2256, S2257, N2262, Y2263, I2278, E2279, K2281, F2283, F2285, M2291, Q2308, D2312, E2313, N2314, F2315, E2316
Source molecule (GenBank): P18177.3
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope 4 of B39 VHH on C. difficile TcdB-B1
Chemical type: Discontinuous protein residues
Discontinuous residues: L2255, I2256, S2257, N2262, Y2263, I2278, E2279, K2281, F2283, F2285, M2291, Q2308, D2312, E2313, N2314, F2315, E2316
Source molecule (GenBank): P18177.3
Assay category: BCell
Result: Positive
Quantitative measurement: 2.5
Host: M