Reference: Netanel Tzarum; Erick Giang; Rameshwar U Kadam; Fang Chen; Kenna Nagy; Elias H Augestad; Rodrigo Velázquez-Moctezuma; Zhen-Yong Keck; Yuanzi Hua; Robyn L Stanfield; Marlene Dreux; Jannick Prentoe; Steven K H Foung; Jens Bukh; Ian A Wilson; Mansun Law. "An alternate conformation of HCV E2 neutralizing face as an additional vaccine target." Science advances (2020).

Epitope: Epitope of U1 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L427, N428, C429, N430, I438, T439, F442, Y443, R502, N530, W531, E533
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive

Epitope: Epitope of U1 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L427, N428, C429, N430, I438, T439, F442, Y443, R502, N530, W531, E533
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive

Epitope: Epitope of U1 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L427, N428, C429, N430, I438, T439, F442, Y443, R502, N530, W531, E533
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive

Epitope: Epitope of U1 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L427, N428, C429, N430, I438, T439, F442, Y443, R502, N530, W531, E533
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive

Epitope: Epitope of U1 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L427, N428, C429, N430, I438, T439, F442, Y443, R502, N530, W531, E533
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive

Epitope: Epitope of U1 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L427, N428, C429, N430, I438, T439, F442, Y443, R502, N530, W531, E533
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.38

Epitope: Epitope of E1 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T510, V514, S522, G523, A524, P525, V538, N540, N541, T542, R543, P545, L546, G547, N548, W549
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive
Quantitative measurement: 3.67

Epitope: Epitope of E1 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T510, V514, S522, G523, A524, P525, V538, N540, N541, T542, R543, P545, L546, G547, N548, W549
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive
Quantitative measurement: 2.62

Epitope: Epitope of 212.1.1 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T425, L427, N428, C429, E431, L433, N434, T435, G436, L438, C503, G504, W529, A531, Y613, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive
Quantitative measurement: 2.62
Host: M 21 years

Epitope: Epitope of 212.1.1 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T425, L427, N428, C429, E431, L433, N434, T435, G436, L438, C503, G504, W529, A531, Y613, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive
Host: M 21 years

Epitope: Epitope of 212.1.1 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T425, L427, N428, C429, E431, L433, N434, T435, G436, L438, C503, G504, W529, A531, Y613, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive
Host: M 21 years

Epitope: Epitope of 212.1.1 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T425, L427, N428, C429, E431, L433, N434, T435, G436, L438, C503, G504, W529, A531, Y613, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive
Host: M 21 years

Epitope: Epitope of 212.1.1 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T425, L427, N428, C429, E431, L433, N434, T435, G436, L438, C503, G504, W529, A531, Y613, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.1
Host: M 21 years

Epitope: Epitope of HC1AM Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: W420, I422, N423, L427, N428, C429, K500, G504, Y527, S528, W529, A531, N532, D533, Y613, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive
Quantitative measurement: 3.67

Epitope: Epitope of HC1AM Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: W420, I422, N423, L427, N428, C429, K500, G504, Y527, S528, W529, A531, N532, D533, Y613, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive
Quantitative measurement: 5.0

Epitope: Epitope of HC1AM Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: W420, I422, N423, L427, N428, C429, K500, G504, Y527, S528, W529, A531, N532, D533, Y613, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC1AM Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: W420, I422, N423, L427, N428, C429, K500, G504, Y527, S528, W529, A531, N532, D533, Y613, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC1AM Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: W420, I422, N423, L427, N428, C429, K500, G504, Y527, S528, W529, A531, N532, D533, Y613, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC1AM Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: W420, I422, N423, L427, N428, C429, K500, G504, Y527, S528, W529, A531, N532, D533, Y613, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC1AM Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: W420, I422, N423, L427, N428, C429, K500, G504, Y527, S528, W529, A531, N532, D533, Y613, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC1AM Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: W420, I422, N423, L427, N428, C429, K500, G504, Y527, S528, W529, A531, N532, D533, Y613, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC1AM Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: W420, I422, N423, L427, N428, C429, K500, G504, Y527, S528, W529, A531, N532, D533, Y613, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC1AM Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: W420, I422, N423, L427, N428, C429, K500, G504, Y527, S528, W529, A531, N532, D533, Y613, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC11 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L427, N428, C429, N430, D431, S432, Q434, I438, T439, F442, Y443, W531, E533
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive

Epitope: Epitope of HC11 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L427, N428, C429, N430, D431, S432, Q434, I438, T439, F442, Y443, W531, E533
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive

Epitope: Epitope of HC11 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L427, N428, C429, N430, D431, S432, Q434, I438, T439, F442, Y443, W531, E533
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive

Epitope: Epitope of HC11 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L427, N428, C429, N430, D431, S432, Q434, I438, T439, F442, Y443, W531, E533
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive

Epitope: Epitope of HC11 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L427, N428, C429, N430, D431, S432, Q434, I438, T439, F442, Y443, W531, E533
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive

Epitope: Epitope of HC11 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L427, N428, C429, N430, D431, S432, Q434, I438, T439, F442, Y443, W531, E533
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive

Epitope: Epitope of HC11 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L427, N428, C429, N430, D431, S432, Q434, I438, T439, F442, Y443, W531, E533
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.1

Epitope: Epitope of HC11 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L427, N428, C429, N430, D431, S432, Q434, I438, T439, F442, Y443, W531, E533
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.35

Epitope: Epitope of HC11 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L427, N428, C429, N430, D431, S432, Q434, I438, T439, F442, Y443, W531, E533
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive

Epitope: Epitope of HC11 Fab on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L427, N428, C429, N430, D431, S432, Q434, I438, T439, F442, Y443, W531, E533
Source molecule (GenBank): ACM69040.1
Assay category: BCell
Result: Positive