Reference: Christine McInnis; Shilpa Bhatia; Brinda Vijaykumar; Qiaomu Tian; Yanbo Sun; Del Leistritz-Edwards; Charles T Quinn; Ravi Uppaluri; Ann Marie Egloff; Lakshmi Srinivasan; Daniel C Pregibon; Anthony J Coyle; Glenn J Hanna. "Identification of HPV16 E1 and E2-specific T cells in the oropharyngeal cancer tumor microenvironment." Journal for immunotherapy of cancer (2023).

Epitope: WPY-HPV16 E1
Chemical type: Peptide from protein
Sequence: WPYLHNRLV
Position: 576-584
Source molecule (GenBank): P03114.2
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: lymphoid
Culture conditions: Engineered

Epitope: QVD-HPV16 E2
Chemical type: Peptide from protein
Sequence: QVDYYGLYY
Position: 151-159
Source molecule (GenBank): P03120.1
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: lymphoid
Culture conditions: Engineered

Epitope: YSK-HPV16 E2
Chemical type: Peptide from protein
Sequence: YSKNKVWEV
Position: 178-186
Source molecule (GenBank): P03120.1
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: lymphoid
Culture conditions: Engineered

Epitope: KFK-HPV16 E1
Chemical type: Peptide from protein
Sequence: KFKELYGVSFSELVR
Position: 210-224
Source molecule (GenBank): P03114.2
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: lymphoid
Culture conditions: Engineered

Epitope: KQR-HPV16 E6
Chemical type: Peptide from protein
Sequence: KQRHLDKKQRFHNIRGRWTGR
Position: 122-142
Source molecule (GenBank): P03126
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: lymphoid
Culture conditions: Engineered

Epitope: LDK-HPV16 E6
Chemical type: Peptide from protein
Sequence: LDKKQRFHNIRGRWTGRCMSC
Position: 126-146
Source molecule (GenBank): P03126
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: lymphoid
Culture conditions: Engineered

Epitope: KLMSNLLSI
Chemical type: Peptide from protein
Sequence: KLMSNLLSI
Position: 285-293
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: GMIDDVTPI
Chemical type: Peptide from protein
Sequence: GMIDDVTPI
Position: 512-520
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: SLYTHLQCL
Chemical type: Peptide from protein
Sequence: SLYTHLQCL
Position: 252-260
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: NIFDLSEMV
Chemical type: Peptide from protein
Sequence: NIFDLSEMV
Position: 346-354
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: FLGAFKKFL
Chemical type: Peptide from protein
Sequence: FLGAFKKFL
Position: 449-457
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: TLQEISNVL
Chemical type: Peptide from protein
Sequence: TLQEISNVL
Position: 183-191
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: ALYWFRTAM
Chemical type: Peptide from protein
Sequence: ALYWFRTAM
Position: 311-319
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: ALDGNEISI
Chemical type: Peptide from protein
Sequence: ALDGNEISI
Position: 532-540
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: YIDDYMRNA
Chemical type: Peptide from protein
Sequence: YIDDYMRNA
Position: 524-532
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: MLICGPANT
Chemical type: Peptide from protein
Sequence: MLICGPANT
Position: 466-474
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: FGMSLIQFL
Chemical type: Peptide from protein
Sequence: FGMSLIQFL
Position: 479-487
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: RTWCKLDLI
Chemical type: Peptide from protein
Sequence: RTWCKLDLI
Position: 608-616
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: KLFCADPAL
Chemical type: Peptide from protein
Sequence: KLFCADPAL
Position: 242-250
Source molecule (GenBank): P06423.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: YTNWGEIYI
Chemical type: Peptide from protein
Sequence: YTNWGEIYI
Position: 131-139
Source molecule (GenBank): P06423.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: KLIRMECAL
Chemical type: Peptide from protein
Sequence: KLIRMECAL
Position: 34-42
Source molecule (GenBank): P06423.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: QMFLGTVKI
Chemical type: Peptide from protein
Sequence: QMFLGTVKI
Position: 332-340
Source molecule (GenBank): P06423.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: TLQQTSLEV
Chemical type: Peptide from protein
Sequence: TLQQTSLEV
Position: 93-101
Source molecule (GenBank): P06423.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: KQMGFSHLC
Chemical type: Peptide from protein
Sequence: KQMGFSHLC
Position: 47-55
Source molecule (GenBank): P06423.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: QVIELQMAL
Chemical type: Peptide from protein
Sequence: QVIELQMAL
Position: 71-79
Source molecule (GenBank): P06423.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: FVLCFILFL
Chemical type: Peptide from protein
Sequence: FVLCFILFL
Position: 5-13
Source molecule (GenBank): P06426.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: YLLFLYLPM
Chemical type: Peptide from protein
Sequence: YLLFLYLPM
Position: 53-61
Source molecule (GenBank): P06426.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: FLYLPMMCI
Chemical type: Peptide from protein
Sequence: FLYLPMMCI
Position: 56-64
Source molecule (GenBank): P06426.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: ILFLCLSLL
Chemical type: Peptide from protein
Sequence: ILFLCLSLL
Position: 10-18
Source molecule (GenBank): P06426.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: WLLVLVLLL
Chemical type: Peptide from protein
Sequence: WLLVLVLLL
Position: 31-39
Source molecule (GenBank): P06426.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: LLFLYLPMM
Chemical type: Peptide from protein
Sequence: LLFLYLPMM
Position: 54-62
Source molecule (GenBank): P06426.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: SISTYAWLL
Chemical type: Peptide from protein
Sequence: SISTYAWLL
Position: 25-33
Source molecule (GenBank): P06426.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: LILSISTYA
Chemical type: Peptide from protein
Sequence: LILSISTYA
Position: 22-30
Source molecule (GenBank): P06426.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: FILFLCLSL
Chemical type: Peptide from protein
Sequence: FILFLCLSL
Position: 9-17
Source molecule (GenBank): P06426.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: STYAWLLVL
Chemical type: Peptide from protein
Sequence: STYAWLLVL
Position: 27-35
Source molecule (GenBank): P06426.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: CLSLLLRPL
Chemical type: Peptide from protein
Sequence: CLSLLLRPL
Position: 14-22
Source molecule (GenBank): P06426.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: SLLLRPLIL
Chemical type: Peptide from protein
Sequence: SLLLRPLIL
Position: 16-24
Source molecule (GenBank): P06426.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: FAFADLTVV
Chemical type: Peptide from protein
Sequence: FAFADLTVV
Position: 45-53
Source molecule (GenBank): P06427.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: TLHDLCQAL
Chemical type: Peptide from protein
Sequence: TLHDLCQAL
Position: 11-19
Source molecule (GenBank): P06427.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: ALETTIHNI
Chemical type: Peptide from protein
Sequence: ALETTIHNI
Position: 18-26
Source molecule (GenBank): P06427.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: QLLMGTVNI
Chemical type: Peptide from protein
Sequence: QLLMGTVNI
Position: 81-89
Source molecule (GenBank): P06429.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: TLKEYVLDL
Chemical type: Peptide from protein
Sequence: TLKEYVLDL
Position: 7-15
Source molecule (GenBank): P06429.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: oropharynx
Culture conditions: Direct Ex Vivo

Epitope: VYAINDENW
Chemical type: Peptide from protein
Sequence: VYAINDENW
Position: 594-602
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: AFLGAFKKF
Chemical type: Peptide from protein
Sequence: AFLGAFKKF
Position: 448-456
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: YFGMSLIQF
Chemical type: Peptide from protein
Sequence: YFGMSLIQF
Position: 478-486
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: AYGISFMEL
Chemical type: Peptide from protein
Sequence: AYGISFMEL
Position: 207-215
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: SFMELVRPF
Chemical type: Peptide from protein
Sequence: SFMELVRPF
Position: 211-219
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RWPYLHSRL
Chemical type: Peptide from protein
Sequence: RWPYLHSRL
Position: 568-576
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PYLHSRLTV
Chemical type: Peptide from protein
Sequence: PYLHSRLTV
Position: 570-578
Source molecule (GenBank): P06421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LYSSMSSTW
Chemical type: Peptide from protein
Sequence: LYSSMSSTW
Position: 299-307
Source molecule (GenBank): P06423.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: QYSTSQWTL
Chemical type: Peptide from protein
Sequence: QYSTSQWTL
Position: 86-94
Source molecule (GenBank): P06423.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LYTAKQMGF
Chemical type: Peptide from protein
Sequence: LYTAKQMGF
Position: 43-51
Source molecule (GenBank): P06423.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: YYIHNCEKV
Chemical type: Peptide from protein
Sequence: YYIHNCEKV
Position: 158-166
Source molecule (GenBank): P06423.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: SSMSSTWHW
Chemical type: Peptide from protein
Sequence: SSMSSTWHW
Position: 301-309
Source molecule (GenBank): P06423.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: TYAWLLVLV
Chemical type: Peptide from protein
Sequence: TYAWLLVLV
Position: 28-36
Source molecule (GenBank): P06426.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: YLPMMCINF
Chemical type: Peptide from protein
Sequence: YLPMMCINF
Position: 58-66
Source molecule (GenBank): P06426.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NYSVYGNTL
Chemical type: Peptide from protein
Sequence: NYSVYGNTL
Position: 80-88
Source molecule (GenBank): P06427.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: RFHNISGRW
Chemical type: Peptide from protein
Sequence: RFHNISGRW
Position: 124-132
Source molecule (GenBank): P06427.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo