Reference: Megan E Schmidt; Steven M Varga. "Identification of Novel Respiratory Syncytial Virus CD4<sup>+</sup> and CD8<sup>+</sup> T Cell Epitopes in C57BL/6 Mice." ImmunoHorizons (2019).

Epitope: SH<sub>41-55</sub>
Chemical type: Peptide from protein
Sequence: LNKLCEYNVFHNKTF
Position: 41-55
Source molecule (GenBank): P0DOE5.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: SH<sub>46-60</sub>
Chemical type: Peptide from protein
Sequence: EYNVFHNKTFELPRA
Position: 46-60
Source molecule (GenBank): P0DOE5.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: SH<sub>50-64</sub>
Chemical type: Peptide from protein
Sequence: FHNKTFELPRARVNT
Position: 50-64
Source molecule (GenBank): P0DOE5.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>11-25</sub>
Chemical type: Peptide from protein
Sequence: EDANNRATKFLESIK
Position: 11-25
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>31-45</sub>
Chemical type: Peptide from protein
Sequence: PKDPKKKDSIISVNS
Position: 31-45
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>51-65</sub>
Chemical type: Peptide from protein
Sequence: TKESPITSNSTIINP
Position: 51-65
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>56-70</sub>
Chemical type: Peptide from protein
Sequence: ITSNSTIINPTNETD
Position: 56-70
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>76-90</sub>
Chemical type: Peptide from protein
Sequence: KPNYQRKPLVSFKED
Position: 76-90
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>91-105</sub>
Chemical type: Peptide from protein
Sequence: PTPSDNPFSKLYKET
Position: 91-105
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>96-110</sub>
Chemical type: Peptide from protein
Sequence: NPFSKLYKETIETFD
Position: 96-110
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>121-135</sub>
Chemical type: Peptide from protein
Sequence: EEINDQTNDNITARL
Position: 121-135
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>126-140</sub>
Chemical type: Peptide from protein
Sequence: QTNDNITARLDRIDE
Position: 126-140
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>131-145</sub>
Chemical type: Peptide from protein
Sequence: ITARLDRIDEKLSEI
Position: 131-145
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>136-150</sub>
Chemical type: Peptide from protein
Sequence: DRIDEKLSEILGMLH
Position: 136-150
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>141-155</sub>
Chemical type: Peptide from protein
Sequence: KLSEILGMLHTLVVA
Position: 141-155
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>151-165</sub>
Chemical type: Peptide from protein
Sequence: TLVVASAGPTSARDG
Position: 151-165
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>156-170</sub>
Chemical type: Peptide from protein
Sequence: SAGPTSARDGIRDAM
Position: 156-170
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>161-175</sub>
Chemical type: Peptide from protein
Sequence: SARDGIRDAMIGLRE
Position: 161-175
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>166-180</sub>
Chemical type: Peptide from protein
Sequence: IRDAMIGLREEMIEK
Position: 166-180
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>171-185</sub>
Chemical type: Peptide from protein
Sequence: IGLREEMIEKIRTEA
Position: 171-185
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>176-190</sub>
Chemical type: Peptide from protein
Sequence: EMIEKIRTEALMTND
Position: 176-190
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>181-195</sub>
Chemical type: Peptide from protein
Sequence: IRTEALMTNDRLEAM
Position: 181-195
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>206-220</sub>
Chemical type: Peptide from protein
Sequence: MAKDTSDEVSLNPTS
Position: 206-220
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: P<sub>221-235</sub>
Chemical type: Peptide from protein
Sequence: EKLNNLLEGNDSDND
Position: 221-235
Source molecule (GenBank): P03421.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: NS2<sub>16-30</sub>
Chemical type: Peptide from protein
Sequence: TDMRPLSLETIITSL
Position: 16-30
Source molecule (GenBank): P04543.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: NS2<sub>21-35</sub>
Chemical type: Peptide from protein
Sequence: LSLETIITSLTRDII
Position: 21-35
Source molecule (GenBank): P04543.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: NS2<sub>36-40</sub>
Chemical type: Peptide from protein
Sequence: THKFIYLINHECIVR
Position: 36-50
Source molecule (GenBank): P04543.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: NS2<sub>56-70</sub>
Chemical type: Peptide from protein
Sequence: QATFTFLVNYEMKLL
Position: 56-70
Source molecule (GenBank): P04543.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: NS2<sub>61-75</sub>
Chemical type: Peptide from protein
Sequence: FLVNYEMKLLHKVGS
Position: 61-75
Source molecule (GenBank): P04543.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: NS2<sub>66-80</sub>
Chemical type: Peptide from protein
Sequence: EMKLLHKVGSTKYKK
Position: 66-80
Source molecule (GenBank): P04543.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: NS2<sub>96-110</sub>
Chemical type: Peptide from protein
Sequence: FINHDGFLECIGIKP
Position: 96-110
Source molecule (GenBank): P04543.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: NS1<sub>61-75</sub>
Chemical type: Peptide from protein
Sequence: TSSDICPNNNIVVKS
Position: 61-75
Source molecule (GenBank): P0DOE9.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: NS1<sub>66-80</sub>
Chemical type: Peptide from protein
Sequence: CPNNNIVVKSNFTTM
Position: 66-80
Source molecule (GenBank): P0DOE9.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: NS1<sub>116-130 </sub>
Chemical type: Peptide from protein
Sequence: KLSDSTMTNYMNQLS
Position: 116-130
Source molecule (GenBank): P0DOE9.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: M<sub>26-40 </sub>
Chemical type: Peptide from protein
Sequence: DDDPASLTIWVPMFQ
Position: 26-40
Source molecule (GenBank): P0DOE7.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: M<sub>106-120</sub>
Chemical type: Peptide from protein
Sequence: VTTPCEIKACSLTCL
Position: 106-120
Source molecule (GenBank): P0DOE7.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: M<sub>111-125</sub>
Chemical type: Peptide from protein
Sequence: EIKACSLTCLKSKNM
Position: 111-125
Source molecule (GenBank): P0DOE7.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: M<sub>136-150</sub>
Chemical type: Peptide from protein
Sequence: TLNPTHDIIALCEFE
Position: 136-150
Source molecule (GenBank): P0DOE7.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: M<sub>146-160 </sub>
Chemical type: Peptide from protein
Sequence: LCEFENIVTSKKVII
Position: 146-160
Source molecule (GenBank): P0DOE7.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: M<sub>181-195</sub>
Chemical type: Peptide from protein
Sequence: TTTEFKNAITNAKII
Position: 181-195
Source molecule (GenBank): P0DOE7.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: M<sub>191-205</sub>
Chemical type: Peptide from protein
Sequence: NAKIIPYSGLLLVIT
Position: 191-205
Source molecule (GenBank): P0DOE7.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: M<sub>221-235 </sub>
Chemical type: Peptide from protein
Sequence: QFIVDLGAYLEKESI
Position: 221-235
Source molecule (GenBank): P0DOE7.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: M2-2<sub>21-35 </sub>
Chemical type: Peptide from protein
Sequence: LITSRCRVTMYNQKN
Position: 21-35
Source molecule (GenBank): P88812.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>276-290</sub>
Chemical type: Peptide from protein
Sequence: SLSRLNVCLITWISN
Position: 276-290
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>386-400</sub>
Chemical type: Peptide from protein
Sequence: KTVSDNIINGRWIIL
Position: 386-400
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>426-440</sub>
Chemical type: Peptide from protein
Sequence: FRIFGHPMVDERQAM
Position: 426-440
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>466-480</sub>
Chemical type: Peptide from protein
Sequence: IYRIIKGFVNNYNRW
Position: 466-480
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>491-505</sub>
Chemical type: Peptide from protein
Sequence: LRWLTYYKLNTYPSL
Position: 491-505
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>526-540</sub>
Chemical type: Peptide from protein
Sequence: RLPKKVDLEMIINDK
Position: 526-540
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>536-550</sub>
Chemical type: Peptide from protein
Sequence: IINDKAISPPKNLIW
Position: 536-550
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>546-560</sub>
Chemical type: Peptide from protein
Sequence: KNLIWTSFPRNYMPS
Position: 546-560
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>576-590</sub>
Chemical type: Peptide from protein
Sequence: SDKSRRVLEYYLRDN
Position: 576-590
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>596-610</sub>
Chemical type: Peptide from protein
Sequence: DLYNCVVNQSYLNNP
Position: 596-610
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>616-630</sub>
Chemical type: Peptide from protein
Sequence: LTGKERELSVGRMFA
Position: 616-630
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>626-640</sub>
Chemical type: Peptide from protein
Sequence: GRMFAMQPGMFRQVQ
Position: 626-640
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>666-680</sub>
Chemical type: Peptide from protein
Sequence: ELQKILELKAGISNK
Position: 666-680
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>701-715</sub>
Chemical type: Peptide from protein
Sequence: LSKFNQAFRYETSCI
Position: 701-715
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>706-720</sub>
Chemical type: Peptide from protein
Sequence: QAFRYETSCICSDVL
Position: 706-720
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>736-750</sub>
Chemical type: Peptide from protein
Sequence: TIPHVTIICTYRHAP
Position: 736-750
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>771-785</sub>
Chemical type: Peptide from protein
Sequence: RYHMGGIEGWCQKLW
Position: 771-785
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>821-835</sub>
Chemical type: Peptide from protein
Sequence: IRLMEGQTHAQADYL
Position: 821-835
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>2016-2030 </sub>
Chemical type: Peptide from protein
Sequence: IFPVFNVVQNAKLIL
Position: 2016-2030
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>2021-2035 </sub>
Chemical type: Peptide from protein
Sequence: NVVQNAKLILSRTKN
Position: 2021-2035
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: NS1<sub>65-73</sub>
Chemical type: Peptide from protein
Sequence: ICPNNNIVV
Position: 65-73
Source molecule (GenBank): P0DOE9.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: M<sub>112-120</sub>
Chemical type: Peptide from protein
Sequence: IKACSLTCL
Position: 112-120
Source molecule (GenBank): P0DOE7.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo

Epitope: L<sub>2021-2029 </sub>
Chemical type: Peptide from protein
Sequence: NVVQNAKLI
Position: 2021-2029
Source molecule (GenBank): P28887.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: Lung
Culture conditions: Direct Ex Vivo