Reference: Daniela P Lage; Patrícia A F Ribeiro; Daniel S Dias; Débora V C Mendonça; Fernanda F Ramos; Lívia M Carvalho; Daysiane de Oliveira; Bethina T Steiner; Vívian T Martins; Luísa Perin; Amanda S Machado; Thaís T O Santos; Grasiele S V Tavares; João A Oliveira-da-Silva; Jamil S Oliveira; Bruno M Roatt; Ricardo A Machado-de-Ávila; Antônio L Teixeira; Maria V Humbert; Eduardo A F Coelho; Myron Christodoulides. "A candidate vaccine for human visceral leishmaniasis based on a specific T cell epitope-containing chimeric protein protects mice against  infection." NPJ vaccines (2020).

Epitope: LiHyp1 epitope
Chemical type: Peptide from protein
Sequence: YIMSGPARYVYFHMVLPVEAQ
Position: 163-183
Source molecule (GenBank): XP_001468941.1
Assay category: TCell
Result: Positive
Host:  24-58 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LiHyp1 epitope
Chemical type: Peptide from protein
Sequence: YIMSGPARYVYFHMVLPVEAQ
Position: 163-183
Source molecule (GenBank): XP_001468941.1
Assay category: TCell
Result: Positive
Host:  24-45 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LiHyp1 epitope
Chemical type: Peptide from protein
Sequence: YIMSGPARYVYFHMVLPVEAQ
Position: 163-183
Source molecule (GenBank): XP_001468941.1
Assay category: TCell
Result: Negative
Host:  24-58 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LiHyp1 epitope
Chemical type: Peptide from protein
Sequence: YIMSGPARYVYFHMVLPVEAQ
Position: 163-183
Source molecule (GenBank): XP_001468941.1
Assay category: TCell
Result: Negative
Host:  24-45 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LiHyp1 epitope
Chemical type: Peptide from protein
Sequence: YIMSGPARYVYFHMVLPVEAQ
Position: 163-183
Source molecule (GenBank): XP_001468941.1
Assay category: TCell
Result: Positive
Host:  24-45 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LiHyp1 epitope
Chemical type: Peptide from protein
Sequence: YIMSGPARYVYFHMVLPVEAQ
Position: 163-183
Source molecule (GenBank): XP_001468941.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp1 epitope
Chemical type: Peptide from protein
Sequence: YIMSGPARYVYFHMVLPVEAQ
Position: 163-183
Source molecule (GenBank): XP_001468941.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp1 epitope
Chemical type: Peptide from protein
Sequence: YIMSGPARYVYFHMVLPVEAQ
Position: 163-183
Source molecule (GenBank): XP_001468941.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp1 epitope
Chemical type: Peptide from protein
Sequence: YIMSGPARYVYFHMVLPVEAQ
Position: 163-183
Source molecule (GenBank): XP_001468941.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp1 epitope
Chemical type: Peptide from protein
Sequence: YIMSGPARYVYFHMVLPVEAQ
Position: 163-183
Source molecule (GenBank): XP_001468941.1
Assay category: TCell
Result: Positive-Low
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp1 epitope
Chemical type: Peptide from protein
Sequence: YIMSGPARYVYFHMVLPVEAQ
Position: 163-183
Source molecule (GenBank): XP_001468941.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp1 epitope
Chemical type: Peptide from protein
Sequence: YIMSGPARYVYFHMVLPVEAQ
Position: 163-183
Source molecule (GenBank): XP_001468941.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp1 epitope
Chemical type: Peptide from protein
Sequence: YIMSGPARYVYFHMVLPVEAQ
Position: 163-183
Source molecule (GenBank): XP_001468941.1
Assay category: TCell
Result: Positive-Low
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp1 epitope
Chemical type: Peptide from protein
Sequence: YIMSGPARYVYFHMVLPVEAQ
Position: 163-183
Source molecule (GenBank): XP_001468941.1
Assay category: TCell
Result: Positive-Low
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp1 epitope
Chemical type: Peptide from protein
Sequence: YIMSGPARYVYFHMVLPVEAQ
Position: 163-183
Source molecule (GenBank): XP_001468941.1
Assay category: TCell
Result: Positive
Host:  24-58 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LiHyp1 epitope
Chemical type: Peptide from protein
Sequence: YIMSGPARYVYFHMVLPVEAQ
Position: 163-183
Source molecule (GenBank): XP_001468941.1
Assay category: TCell
Result: Positive-Low
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EIF5a epitope
Chemical type: Peptide from protein
Sequence: RLEDQAPSTHNVEVPFVKTFTYSVLDIQPNE
Position: 71-101
Source molecule (GenBank): XP_001466105.1
Assay category: TCell
Result: Positive
Host:  24-58 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: EIF5a epitope
Chemical type: Peptide from protein
Sequence: RLEDQAPSTHNVEVPFVKTFTYSVLDIQPNE
Position: 71-101
Source molecule (GenBank): XP_001466105.1
Assay category: TCell
Result: Positive
Host:  24-45 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: EIF5a epitope
Chemical type: Peptide from protein
Sequence: RLEDQAPSTHNVEVPFVKTFTYSVLDIQPNE
Position: 71-101
Source molecule (GenBank): XP_001466105.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EIF5a epitope
Chemical type: Peptide from protein
Sequence: RLEDQAPSTHNVEVPFVKTFTYSVLDIQPNE
Position: 71-101
Source molecule (GenBank): XP_001466105.1
Assay category: TCell
Result: Positive-Low
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EIF5a epitope
Chemical type: Peptide from protein
Sequence: RLEDQAPSTHNVEVPFVKTFTYSVLDIQPNE
Position: 71-101
Source molecule (GenBank): XP_001466105.1
Assay category: TCell
Result: Positive-Low
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EIF5a epitope
Chemical type: Peptide from protein
Sequence: RLEDQAPSTHNVEVPFVKTFTYSVLDIQPNE
Position: 71-101
Source molecule (GenBank): XP_001466105.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EIF5a epitope
Chemical type: Peptide from protein
Sequence: RLEDQAPSTHNVEVPFVKTFTYSVLDIQPNE
Position: 71-101
Source molecule (GenBank): XP_001466105.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EIF5a epitope
Chemical type: Peptide from protein
Sequence: RLEDQAPSTHNVEVPFVKTFTYSVLDIQPNE
Position: 71-101
Source molecule (GenBank): XP_001466105.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EIF5a epitope
Chemical type: Peptide from protein
Sequence: RLEDQAPSTHNVEVPFVKTFTYSVLDIQPNE
Position: 71-101
Source molecule (GenBank): XP_001466105.1
Assay category: TCell
Result: Positive-Low
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EIF5a epitope
Chemical type: Peptide from protein
Sequence: RLEDQAPSTHNVEVPFVKTFTYSVLDIQPNE
Position: 71-101
Source molecule (GenBank): XP_001466105.1
Assay category: TCell
Result: Positive-Low
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EIF5a epitope
Chemical type: Peptide from protein
Sequence: RLEDQAPSTHNVEVPFVKTFTYSVLDIQPNE
Position: 71-101
Source molecule (GenBank): XP_001466105.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EIF5a epitope
Chemical type: Peptide from protein
Sequence: RLEDQAPSTHNVEVPFVKTFTYSVLDIQPNE
Position: 71-101
Source molecule (GenBank): XP_001466105.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EIF5a epitope
Chemical type: Peptide from protein
Sequence: RLEDQAPSTHNVEVPFVKTFTYSVLDIQPNE
Position: 71-101
Source molecule (GenBank): XP_001466105.1
Assay category: TCell
Result: Positive
Host:  24-45 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: EIF5a epitope
Chemical type: Peptide from protein
Sequence: RLEDQAPSTHNVEVPFVKTFTYSVLDIQPNE
Position: 71-101
Source molecule (GenBank): XP_001466105.1
Assay category: TCell
Result: Negative
Host:  24-58 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: EIF5a epitope
Chemical type: Peptide from protein
Sequence: RLEDQAPSTHNVEVPFVKTFTYSVLDIQPNE
Position: 71-101
Source molecule (GenBank): XP_001466105.1
Assay category: TCell
Result: Negative
Host:  24-45 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: EIF5a epitope
Chemical type: Peptide from protein
Sequence: RLEDQAPSTHNVEVPFVKTFTYSVLDIQPNE
Position: 71-101
Source molecule (GenBank): XP_001466105.1
Assay category: TCell
Result: Positive
Host:  24-58 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LiHyp2 epitope
Chemical type: Peptide from protein
Sequence: NYDPNVWCAVPNCITCDRLDPSNR
Position: 416-439
Source molecule (GenBank): XP_001462854.1
Assay category: TCell
Result: Positive
Host:  24-45 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LiHyp2 epitope
Chemical type: Peptide from protein
Sequence: NYDPNVWCAVPNCITCDRLDPSNR
Position: 416-439
Source molecule (GenBank): XP_001462854.1
Assay category: TCell
Result: Positive-Low
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp2 epitope
Chemical type: Peptide from protein
Sequence: NYDPNVWCAVPNCITCDRLDPSNR
Position: 416-439
Source molecule (GenBank): XP_001462854.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp2 epitope
Chemical type: Peptide from protein
Sequence: NYDPNVWCAVPNCITCDRLDPSNR
Position: 416-439
Source molecule (GenBank): XP_001462854.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp2 epitope
Chemical type: Peptide from protein
Sequence: NYDPNVWCAVPNCITCDRLDPSNR
Position: 416-439
Source molecule (GenBank): XP_001462854.1
Assay category: TCell
Result: Positive
Host:  24-58 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LiHyp2 epitope
Chemical type: Peptide from protein
Sequence: NYDPNVWCAVPNCITCDRLDPSNR
Position: 416-439
Source molecule (GenBank): XP_001462854.1
Assay category: TCell
Result: Positive-Low
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp2 epitope
Chemical type: Peptide from protein
Sequence: NYDPNVWCAVPNCITCDRLDPSNR
Position: 416-439
Source molecule (GenBank): XP_001462854.1
Assay category: TCell
Result: Positive-Low
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp2 epitope
Chemical type: Peptide from protein
Sequence: NYDPNVWCAVPNCITCDRLDPSNR
Position: 416-439
Source molecule (GenBank): XP_001462854.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp2 epitope
Chemical type: Peptide from protein
Sequence: NYDPNVWCAVPNCITCDRLDPSNR
Position: 416-439
Source molecule (GenBank): XP_001462854.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp2 epitope
Chemical type: Peptide from protein
Sequence: NYDPNVWCAVPNCITCDRLDPSNR
Position: 416-439
Source molecule (GenBank): XP_001462854.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp2 epitope
Chemical type: Peptide from protein
Sequence: NYDPNVWCAVPNCITCDRLDPSNR
Position: 416-439
Source molecule (GenBank): XP_001462854.1
Assay category: TCell
Result: Positive-Low
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp2 epitope
Chemical type: Peptide from protein
Sequence: NYDPNVWCAVPNCITCDRLDPSNR
Position: 416-439
Source molecule (GenBank): XP_001462854.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LiHyp2 epitope
Chemical type: Peptide from protein
Sequence: NYDPNVWCAVPNCITCDRLDPSNR
Position: 416-439
Source molecule (GenBank): XP_001462854.1
Assay category: TCell
Result: Positive
Host:  24-58 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LiHyp2 epitope
Chemical type: Peptide from protein
Sequence: NYDPNVWCAVPNCITCDRLDPSNR
Position: 416-439
Source molecule (GenBank): XP_001462854.1
Assay category: TCell
Result: Positive
Host:  24-45 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LiHyp2 epitope
Chemical type: Peptide from protein
Sequence: NYDPNVWCAVPNCITCDRLDPSNR
Position: 416-439
Source molecule (GenBank): XP_001462854.1
Assay category: TCell
Result: Negative
Host:  24-58 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LiHyp2 epitope
Chemical type: Peptide from protein
Sequence: NYDPNVWCAVPNCITCDRLDPSNR
Position: 416-439
Source molecule (GenBank): XP_001462854.1
Assay category: TCell
Result: Negative
Host:  24-45 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PHB epitope
Chemical type: Peptide from protein
Sequence: VRVLYQPNVENLYHIYRHIGVNYAETVL
Position: 104-131
Source molecule (GenBank): XP_001468827.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PHB epitope
Chemical type: Peptide from protein
Sequence: VRVLYQPNVENLYHIYRHIGVNYAETVL
Position: 104-131
Source molecule (GenBank): XP_001468827.1
Assay category: TCell
Result: Positive-Low
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PHB epitope
Chemical type: Peptide from protein
Sequence: VRVLYQPNVENLYHIYRHIGVNYAETVL
Position: 104-131
Source molecule (GenBank): XP_001468827.1
Assay category: TCell
Result: Positive-Low
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PHB epitope
Chemical type: Peptide from protein
Sequence: VRVLYQPNVENLYHIYRHIGVNYAETVL
Position: 104-131
Source molecule (GenBank): XP_001468827.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PHB epitope
Chemical type: Peptide from protein
Sequence: VRVLYQPNVENLYHIYRHIGVNYAETVL
Position: 104-131
Source molecule (GenBank): XP_001468827.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PHB epitope
Chemical type: Peptide from protein
Sequence: VRVLYQPNVENLYHIYRHIGVNYAETVL
Position: 104-131
Source molecule (GenBank): XP_001468827.1
Assay category: TCell
Result: Positive-Low
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PHB epitope
Chemical type: Peptide from protein
Sequence: VRVLYQPNVENLYHIYRHIGVNYAETVL
Position: 104-131
Source molecule (GenBank): XP_001468827.1
Assay category: TCell
Result: Positive-Low
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PHB epitope
Chemical type: Peptide from protein
Sequence: VRVLYQPNVENLYHIYRHIGVNYAETVL
Position: 104-131
Source molecule (GenBank): XP_001468827.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PHB epitope
Chemical type: Peptide from protein
Sequence: VRVLYQPNVENLYHIYRHIGVNYAETVL
Position: 104-131
Source molecule (GenBank): XP_001468827.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PHB epitope
Chemical type: Peptide from protein
Sequence: VRVLYQPNVENLYHIYRHIGVNYAETVL
Position: 104-131
Source molecule (GenBank): XP_001468827.1
Assay category: TCell
Result: Positive
Host:  24-58 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PHB epitope
Chemical type: Peptide from protein
Sequence: VRVLYQPNVENLYHIYRHIGVNYAETVL
Position: 104-131
Source molecule (GenBank): XP_001468827.1
Assay category: TCell
Result: Positive
Host:  24-45 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PHB epitope
Chemical type: Peptide from protein
Sequence: VRVLYQPNVENLYHIYRHIGVNYAETVL
Position: 104-131
Source molecule (GenBank): XP_001468827.1
Assay category: TCell
Result: Positive
Host:  24-58 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PHB epitope
Chemical type: Peptide from protein
Sequence: VRVLYQPNVENLYHIYRHIGVNYAETVL
Position: 104-131
Source molecule (GenBank): XP_001468827.1
Assay category: TCell
Result: Positive
Host:  24-45 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PHB epitope
Chemical type: Peptide from protein
Sequence: VRVLYQPNVENLYHIYRHIGVNYAETVL
Position: 104-131
Source molecule (GenBank): XP_001468827.1
Assay category: TCell
Result: Negative
Host:  24-58 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PHB epitope
Chemical type: Peptide from protein
Sequence: VRVLYQPNVENLYHIYRHIGVNYAETVL
Position: 104-131
Source molecule (GenBank): XP_001468827.1
Assay category: TCell
Result: Negative
Host:  24-45 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PHB epitope
Chemical type: Peptide from protein
Sequence: VRVLYQPNVENLYHIYRHIGVNYAETVL
Position: 104-131
Source molecule (GenBank): XP_001468827.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo