Reference: Xiaorong Chen; Huimin Ke; Wei Li; Lu Yin; Wei Chen; Tao Chen; Yiliang Wu; Jiwan Qiu; Wei Feng. "Structural basis for the recognition of IFNAR1 by the humanized therapeutic monoclonal antibody QX006N for the treatment of systemic lupus erythematosus." International journal of biological macromolecules (2024).

Epitope: Epitope of QX006N Fab on IFNAR1
Chemical type: Discontinuous protein residues
Discontinuous residues: W261, H263, F265, L266, L274, Y275, K276, K278, Q279, I280, P281, D282, E284, P294, N296, V297, F298, Q299, K300, G301, I302, Y303
Source molecule (GenBank): P17181.3
Assay category: BCell
Result: Positive
Quantitative measurement: 2.86

Epitope: Epitope of QX006N Fab on IFNAR1
Chemical type: Discontinuous protein residues
Discontinuous residues: W261, H263, F265, L266, L274, Y275, K276, K278, Q279, I280, P281, D282, E284, P294, N296, V297, F298, Q299, K300, G301, I302, Y303
Source molecule (GenBank): P17181.3
Assay category: BCell
Result: Positive

Epitope: Epitope of QX006N Fab on IFNAR1
Chemical type: Discontinuous protein residues
Discontinuous residues: W261, H263, F265, L266, L274, Y275, K276, K278, Q279, I280, P281, D282, E284, P294, N296, V297, F298, Q299, K300, G301, I302, Y303
Source molecule (GenBank): P17181.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0335

Epitope: Epitope of QX006N Fab on IFNAR1
Chemical type: Discontinuous protein residues
Discontinuous residues: W261, H263, F265, L266, L274, Y275, K276, K278, Q279, I280, P281, D282, E284, P294, N296, V297, F298, Q299, K300, G301, I302, Y303
Source molecule (GenBank): P17181.3
Assay category: BCell
Result: Positive
Quantitative measurement: 1220000.0

Epitope: Epitope of QX006N Fab on IFNAR1
Chemical type: Discontinuous protein residues
Discontinuous residues: W261, H263, F265, L266, L274, Y275, K276, K278, Q279, I280, P281, D282, E284, P294, N296, V297, F298, Q299, K300, G301, I302, Y303
Source molecule (GenBank): P17181.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000041

Epitope: Epitope of QX006N Fab on IFNAR1
Chemical type: Discontinuous protein residues
Discontinuous residues: W261, H263, F265, L266, L274, Y275, K276, K278, Q279, I280, P281, D282, E284, P294, N296, V297, F298, Q299, K300, G301, I302, Y303
Source molecule (GenBank): P17181.3
Assay category: BCell
Result: Positive

Epitope: Epitope of QX006N Fab on IFNAR1
Chemical type: Discontinuous protein residues
Discontinuous residues: W261, H263, F265, L266, L274, Y275, K276, K278, Q279, I280, P281, D282, E284, P294, N296, V297, F298, Q299, K300, G301, I302, Y303
Source molecule (GenBank): P17181.3
Assay category: BCell
Result: Positive
Quantitative measurement: 950000.0

Epitope: Epitope of QX006N Fab on IFNAR1
Chemical type: Discontinuous protein residues
Discontinuous residues: W261, H263, F265, L266, L274, Y275, K276, K278, Q279, I280, P281, D282, E284, P294, N296, V297, F298, Q299, K300, G301, I302, Y303
Source molecule (GenBank): P17181.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000059

Epitope: Epitope of QX006N Fab on IFNAR1
Chemical type: Discontinuous protein residues
Discontinuous residues: W261, H263, F265, L266, L274, Y275, K276, K278, Q279, I280, P281, D282, E284, P294, N296, V297, F298, Q299, K300, G301, I302, Y303
Source molecule (GenBank): P17181.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0623