Reference: Tsvetelina Batsalova; Ivanka Teneva; Krum Bardarov; Dzhemal Moten; Balik Dzhambazov. "Anticitrullinated antibodies recognize rheumatoid arthritis associated T-cell epitopes modified by bacterial L-asparaginase." Central-European journal of immunology (2023).

Epitope: CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: BCell
Result: Negative
MHC allele types: 63
Host: M 45-60 years

Epitope: CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: BCell
Result: Negative
MHC allele types: 63
Host: M 45-60 years

Epitope: CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L-ASNase treated CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: BCell
Result: Positive-Intermediate
MHC allele types: 63
Host: M 45-60 years

Epitope: L-ASNase treated CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: BCell
Result: Positive-Low
MHC allele types: 63
Host: M 45-60 years

Epitope: L-ASNase treated CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: BCell
Result: Positive
MHC allele types: 63
Host: M 45-60 years

Epitope: L-ASNase treated CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L-ASNase treated CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L-ASNase treated CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L-ASNase treated CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CII311-325
Chemical type: Peptide from protein
Sequence: APGNRGFPGQDGLAG
Position: 511-525
Source molecule (GenBank): P02458.3
Assay category: BCell
Result: Positive-Low
MHC allele types: 63
Host: M 45-60 years

Epitope: CII311-325
Chemical type: Peptide from protein
Sequence: APGNRGFPGQDGLAG
Position: 511-525
Source molecule (GenBank): P02458.3
Assay category: BCell
Result: Negative
MHC allele types: 63
Host: M 45-60 years

Epitope: CII311-325
Chemical type: Peptide from protein
Sequence: APGNRGFPGQDGLAG
Position: 511-525
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CII311-325
Chemical type: Peptide from protein
Sequence: APGNRGFPGQDGLAG
Position: 511-525
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CII311-325
Chemical type: Peptide from protein
Sequence: APGNRGFPGQDGLAG
Position: 511-525
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CII311-325
Chemical type: Peptide from protein
Sequence: APGNRGFPGQDGLAG
Position: 511-525
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L-ASNase treated CII311-325
Chemical type: Peptide from protein
Sequence: APGNRGFPGQDGLAG
Position: 511-525
Source molecule (GenBank): P02458.3
Assay category: BCell
Result: Positive-Intermediate
MHC allele types: 63
Host: M 45-60 years

Epitope: L-ASNase treated CII311-325
Chemical type: Peptide from protein
Sequence: APGNRGFPGQDGLAG
Position: 511-525
Source molecule (GenBank): P02458.3
Assay category: BCell
Result: Positive-Low
MHC allele types: 63
Host: M 45-60 years

Epitope: L-ASNase treated CII311-325
Chemical type: Peptide from protein
Sequence: APGNRGFPGQDGLAG
Position: 511-525
Source molecule (GenBank): P02458.3
Assay category: BCell
Result: Positive
MHC allele types: 63
Host: M 45-60 years

Epitope: L-ASNase treated CII311-325
Chemical type: Peptide from protein
Sequence: APGNRGFPGQDGLAG
Position: 511-525
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L-ASNase treated CII311-325
Chemical type: Peptide from protein
Sequence: APGNRGFPGQDGLAG
Position: 511-525
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L-ASNase treated CII311-325
Chemical type: Peptide from protein
Sequence: APGNRGFPGQDGLAG
Position: 511-525
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L-ASNase treated CII311-325
Chemical type: Peptide from protein
Sequence: APGNRGFPGQDGLAG
Position: 511-525
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Gal264-CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: BCell
Result: Negative
MHC allele types: 63
Host: M 45-60 years

Epitope: Gal264-CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: BCell
Result: Negative
MHC allele types: 63
Host: M 45-60 years

Epitope: Gal264-CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Gal264-CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Positive
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Gal264-CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Positive
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Gal264-CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L-ASNase treated Gal264-CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: BCell
Result: Positive
MHC allele types: 63
Host: M 45-60 years

Epitope: L-ASNase treated Gal264-CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: BCell
Result: Positive-Intermediate
MHC allele types: 63
Host: M 45-60 years

Epitope: L-ASNase treated Gal264-CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: BCell
Result: Positive-Low
MHC allele types: 63
Host: M 45-60 years

Epitope: L-ASNase treated Gal264-CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L-ASNase treated Gal264-CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Positive
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L-ASNase treated Gal264-CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Positive
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L-ASNase treated Gal264-CII259-273
Chemical type: Peptide from protein
Sequence: GIAGFKGEQGPKGEP
Position: 459-473
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
MHC allele types: 63
Host: F 45-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Cit35-Fib29-43
Chemical type: Peptide from protein
Sequence: AEGGGVRGPRVVERH
Position: 29-43
Source molecule (GenBank): P02671.2
Assay category: BCell
Result: Positive
MHC allele types: 63
Host: M 45-60 years

Epitope: Cit35-Fib29-43
Chemical type: Peptide from protein
Sequence: AEGGGVRGPRVVERH
Position: 29-43
Source molecule (GenBank): P02671.2
Assay category: BCell
Result: Positive-Low
MHC allele types: 63
Host: M 45-60 years