Reference: I Takahashi; S Mizumo; T Kamiya; J Takamatsu; H Saito. "Epitope mapping of human factor IX inhibitor antibodies." British journal of haematology (1994).

Epitope: Factor IX 1-8
Chemical type: Peptide from protein
Sequence: YNSGKLEE
Position: 47-54
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 7-14
Chemical type: Peptide from protein
Sequence: EEFVQGNL
Position: 53-60
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 13-20
Chemical type: Peptide from protein
Sequence: NLERECME
Position: 59-66
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 19-26
Chemical type: Peptide from protein
Sequence: MEEKCSFE
Position: 65-72
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 25-32
Chemical type: Peptide from protein
Sequence: FEEAREVF
Position: 71-78
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 31-38
Chemical type: Peptide from protein
Sequence: VFENTERT
Position: 77-84
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 37-44
Chemical type: Peptide from protein
Sequence: RTTEFWKQ
Position: 83-90
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 43-50
Chemical type: Peptide from protein
Sequence: KQYVDGDQ
Position: 89-96
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 49-56
Chemical type: Peptide from protein
Sequence: DQCESNPC
Position: 95-102
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 55-62
Chemical type: Peptide from protein
Sequence: PCLNGGSC
Position: 101-108
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 61-68
Chemical type: Peptide from protein
Sequence: SCKDDINS
Position: 107-114
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 67-74
Chemical type: Peptide from protein
Sequence: NSYECWCP
Position: 113-120
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 79-86
Chemical type: Peptide from protein
Sequence: GKNCELDV
Position: 125-132
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 91-98
Chemical type: Peptide from protein
Sequence: KNGRCEQF
Position: 137-144
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 97-104
Chemical type: Peptide from protein
Sequence: QFCKNSAD
Position: 143-150
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 103-110
Chemical type: Peptide from protein
Sequence: ADNKVVCS
Position: 149-156
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 109-116
Chemical type: Peptide from protein
Sequence: CSCTEGYR
Position: 155-162
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 115-122
Chemical type: Peptide from protein
Sequence: YRLAENQK
Position: 161-168
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 121-128
Chemical type: Peptide from protein
Sequence: QKSCEPAV
Position: 167-174
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 127-134
Chemical type: Peptide from protein
Sequence: AVPFPCGR
Position: 173-180
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 133-140
Chemical type: Peptide from protein
Sequence: GRVSVSQT
Position: 179-186
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 139-146
Chemical type: Peptide from protein
Sequence: QTSKLTRA
Position: 185-192
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 145-152
Chemical type: Peptide from protein
Sequence: RAEAVFPD
Position: 191-198
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 157-164
Chemical type: Peptide from protein
Sequence: NSTEAETI
Position: 203-210
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 175-182
Chemical type: Peptide from protein
Sequence: FNDFTRVV
Position: 221-228
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 205-212
Chemical type: Peptide from protein
Sequence: FCGGSIVN
Position: 251-258
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 211-218
Chemical type: Peptide from protein
Sequence: VNEKWIVT
Position: 257-264
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 217-224
Chemical type: Peptide from protein
Sequence: VTAAHCVE
Position: 263-270
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 223-230
Chemical type: Peptide from protein
Sequence: VETGVKIT
Position: 269-276
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 229-236
Chemical type: Peptide from protein
Sequence: ITVVAGEH
Position: 275-282
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 235-242
Chemical type: Peptide from protein
Sequence: EHNIEETE
Position: 281-288
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 241-248
Chemical type: Peptide from protein
Sequence: TEHTEQKR
Position: 287-294
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 247-254
Chemical type: Peptide from protein
Sequence: KRNVIRII
Position: 293-300
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 253-260
Chemical type: Peptide from protein
Sequence: IIPHHNYN
Position: 299-306
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 259-266
Chemical type: Peptide from protein
Sequence: YNAAINKY
Position: 305-312
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 265-272
Chemical type: Peptide from protein
Sequence: KYNHDIAL
Position: 311-318
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 271-278
Chemical type: Peptide from protein
Sequence: ALLELDEP
Position: 317-324
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 277-284
Chemical type: Peptide from protein
Sequence: EPLVLNSY
Position: 323-330
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 283-290
Chemical type: Peptide from protein
Sequence: SYVTPICI
Position: 329-336
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 295-302
Chemical type: Peptide from protein
Sequence: YTNIFLKF
Position: 341-348
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 301-308
Chemical type: Peptide from protein
Sequence: KFGSGYVS
Position: 347-354
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 307-314
Chemical type: Peptide from protein
Sequence: VSGWGRVF
Position: 353-360
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 313-320
Chemical type: Peptide from protein
Sequence: VFHKGRSA
Position: 359-366
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 325-332
Chemical type: Peptide from protein
Sequence: YLRVPLVD
Position: 371-378
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 331-338
Chemical type: Peptide from protein
Sequence: VDRATCLR
Position: 377-384
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 337-344
Chemical type: Peptide from protein
Sequence: LRSTKFTI
Position: 383-390
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 343-350
Chemical type: Peptide from protein
Sequence: TIYNNMFC
Position: 389-396
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 349-356
Chemical type: Peptide from protein
Sequence: FCAGFHEG
Position: 395-402
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 355-362
Chemical type: Peptide from protein
Sequence: EGGRDSCQ
Position: 401-408
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 361-368
Chemical type: Peptide from protein
Sequence: CQGDSGGP
Position: 407-414
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 367-374
Chemical type: Peptide from protein
Sequence: GPHVTEVE
Position: 413-420
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 373-380
Chemical type: Peptide from protein
Sequence: VEGTSFLT
Position: 419-426
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 379-386
Chemical type: Peptide from protein
Sequence: LTGIISWG
Position: 425-432
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 391-398
Chemical type: Peptide from protein
Sequence: MKGKYGIY
Position: 437-444
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 397-404
Chemical type: Peptide from protein
Sequence: IYTKVSRY
Position: 443-450
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 403-410
Chemical type: Peptide from protein
Sequence: RYVNWIKE
Position: 449-456
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 141-148
Chemical type: Peptide from protein
Sequence: SKLTRAEA
Position: 187-194
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 142-149
Chemical type: Peptide from protein
Sequence: KLTRAEAV
Position: 188-195
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 143-150
Chemical type: Peptide from protein
Sequence: LTRAEAVF
Position: 189-196
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 144-151
Chemical type: Peptide from protein
Sequence: TRAEAVFP
Position: 190-197
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 146-153
Chemical type: Peptide from protein
Sequence: AEAVFPDV
Position: 192-199
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 147-154
Chemical type: Peptide from protein
Sequence: EAVFPDVD
Position: 193-200
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 148-155
Chemical type: Peptide from protein
Sequence: AVFPDVDY
Position: 194-201
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 149-156
Chemical type: Peptide from protein
Sequence: VFPDVDYV
Position: 195-202
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 150-157
Chemical type: Peptide from protein
Sequence: FPDVDYVN
Position: 196-203
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 151-158
Chemical type: Peptide from protein
Sequence: PDVDYVNS
Position: 197-204
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 152-159
Chemical type: Peptide from protein
Sequence: DVDYVNST
Position: 198-205
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 153-160
Chemical type: Peptide from protein
Sequence: VDYVNSTE
Position: 199-206
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 154-161
Chemical type: Peptide from protein
Sequence: DYVNSTEA
Position: 200-207
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 155-162
Chemical type: Peptide from protein
Sequence: YVNSTEAE
Position: 201-208
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 156-163
Chemical type: Peptide from protein
Sequence: VNSTEAET
Position: 202-209
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 158-165
Chemical type: Peptide from protein
Sequence: STEAETIL
Position: 204-211
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 159-166
Chemical type: Peptide from protein
Sequence: TEAETILD
Position: 205-212
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 160-167
Chemical type: Peptide from protein
Sequence: EAETILDN
Position: 206-213
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 162-169
Chemical type: Peptide from protein
Sequence: ETILDNIT
Position: 208-215
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 163-170
Chemical type: Peptide from protein
Sequence: TILDNITQ
Position: 209-216
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 164-171
Chemical type: Peptide from protein
Sequence: ILDNITQS
Position: 210-217
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 165-172
Chemical type: Peptide from protein
Sequence: LDNITQST
Position: 211-218
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 166-173
Chemical type: Peptide from protein
Sequence: DNITQSTQ
Position: 212-219
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 168-175
Chemical type: Peptide from protein
Sequence: ITQSTQSF
Position: 214-221
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 170-177
Chemical type: Peptide from protein
Sequence: QSTQSFND
Position: 216-223
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 171-178
Chemical type: Peptide from protein
Sequence: STQSFNDF
Position: 217-224
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 172-179
Chemical type: Peptide from protein
Sequence: TQSFNDFT
Position: 218-225
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 173-180
Chemical type: Peptide from protein
Sequence: QSFNDFTR
Position: 219-226
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 177-184
Chemical type: Peptide from protein
Sequence: DFTRVVGG
Position: 223-230
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 178-185
Chemical type: Peptide from protein
Sequence: FTRVVGGE
Position: 224-231
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 179-186
Chemical type: Peptide from protein
Sequence: TRVVGGED
Position: 225-232
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 180-187
Chemical type: Peptide from protein
Sequence: RVVGGEDA
Position: 226-233
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 181-188
Chemical type: Peptide from protein
Sequence: VVGGEDAK
Position: 227-234
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 182-189
Chemical type: Peptide from protein
Sequence: VGGEDAKP
Position: 228-235
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 183-190
Chemical type: Peptide from protein
Sequence: GGEDAKPG
Position: 229-236
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 184-191
Chemical type: Peptide from protein
Sequence: GEDAKPGQ
Position: 230-237
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 185-192
Chemical type: Peptide from protein
Sequence: EDAKPGQF
Position: 231-238
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 186-193
Chemical type: Peptide from protein
Sequence: DAKPGQFP
Position: 232-239
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 187-194
Chemical type: Peptide from protein
Sequence: AKPGQFPW
Position: 233-240
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 188-195
Chemical type: Peptide from protein
Sequence: KPGQFPWQ
Position: 234-241
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 189-196
Chemical type: Peptide from protein
Sequence: PGQFPWQV
Position: 235-242
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 190-197
Chemical type: Peptide from protein
Sequence: GQFPWQVV
Position: 236-243
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 191-198
Chemical type: Peptide from protein
Sequence: QFPWQVVL
Position: 237-244
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 192-199
Chemical type: Peptide from protein
Sequence: FPWQVVLN
Position: 238-245
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 193-200
Chemical type: Peptide from protein
Sequence: PWQVVLNG
Position: 239-246
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 194-201
Chemical type: Peptide from protein
Sequence: WQVVLNGK
Position: 240-247
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 195-202
Chemical type: Peptide from protein
Sequence: QVVLNGKV
Position: 241-248
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 196-203
Chemical type: Peptide from protein
Sequence: VVLNGKVD
Position: 242-249
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 197-204
Chemical type: Peptide from protein
Sequence: VLNGKVDA
Position: 243-250
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 198-205
Chemical type: Peptide from protein
Sequence: LNGKVDAF
Position: 244-251
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 199-206
Chemical type: Peptide from protein
Sequence: NGKVDAFC
Position: 245-252
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 200-207
Chemical type: Peptide from protein
Sequence: GKVDAFCG
Position: 246-253
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 201-208
Chemical type: Peptide from protein
Sequence: KVDAFCGG
Position: 247-254
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 202-209
Chemical type: Peptide from protein
Sequence: VDAFCGGS
Position: 248-255
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 203-210
Chemical type: Peptide from protein
Sequence: DAFCGGSI
Position: 249-256
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Negative

Epitope: Factor IX 168-182
Chemical type: Peptide from protein
Sequence: ITQSTQSFNDFTRVV
Position: 214-228
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 156-164
Chemical type: Peptide from protein
Sequence: VNSTEAETI
Position: 202-210
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive

Epitope: Factor IX 167-176
Chemical type: Peptide from protein
Sequence: NITQSTQSFN
Position: 213-222
Source molecule (GenBank): AAB59620.1
Assay category: BCell
Result: Positive-Low