Reference: Y Okamoto; T Yanagawa; M E Fisfalen; L J DeGroot. "Proliferative responses of peripheral blood mononuclear cells from patients with Graves' disease to synthetic peptides epitopes of human thyrotropin receptor." Thyroid : official journal of the American Thyroid Association (1994).

Epitope: TSH-R 20-35
Chemical type: Peptide from protein
Sequence: GGMGCSSPPCECHQEE
Position: 20-35
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 20-35
Chemical type: Peptide from protein
Sequence: GGMGCSSPPCECHQEE
Position: 20-35
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 30-49
Chemical type: Peptide from protein
Sequence: ECHQEEDFRVTCKDIQRIPS
Position: 30-49
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 30-49
Chemical type: Peptide from protein
Sequence: ECHQEEDFRVTCKDIQRIPS
Position: 30-49
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
MHC allele types: 341 91 333 89
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 41-60
Chemical type: Peptide from protein
Sequence: CKDIQRIPSLPPSTQTLKLI
Position: 41-60
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 41-60
Chemical type: Peptide from protein
Sequence: CKDIQRIPSLPPSTQTLKLI
Position: 41-60
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 61-80
Chemical type: Peptide from protein
Sequence: ETHLRTIPSHAFSNLPNISR
Position: 61-80
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 61-80
Chemical type: Peptide from protein
Sequence: ETHLRTIPSHAFSNLPNISR
Position: 61-80
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
MHC allele types: 341 91
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 71-90
Chemical type: Peptide from protein
Sequence: AFSNLPNISRIYVSIDVTLQ
Position: 71-90
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 71-90
Chemical type: Peptide from protein
Sequence: AFSNLPNISRIYVSIDVTLQ
Position: 71-90
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 81-100
Chemical type: Peptide from protein
Sequence: IYVSIDVTLQQLESHSFYNL
Position: 81-100
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 81-100
Chemical type: Peptide from protein
Sequence: IYVSIDVTLQQLESHSFYNL
Position: 81-100
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
MHC allele types: 339 89 330 90
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 97-112
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTR
Position: 97-112
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 97-112
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTR
Position: 97-112
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 109-124
Chemical type: Peptide from protein
Sequence: RNTRNLTYIDPDALKE
Position: 109-124
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 109-124
Chemical type: Peptide from protein
Sequence: RNTRNLTYIDPDALKE
Position: 109-124
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 121-140
Chemical type: Peptide from protein
Sequence: ALKELPLLKFLGIFNTGLKM
Position: 121-140
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
MHC allele types: 341 91 333 89
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 121-140
Chemical type: Peptide from protein
Sequence: ALKELPLLKFLGIFNTGLKM
Position: 121-140
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 141-160
Chemical type: Peptide from protein
Sequence: FPDLTKVYSTDIFFILEITD
Position: 141-160
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 141-160
Chemical type: Peptide from protein
Sequence: FPDLTKVYSTDIFFILEITD
Position: 141-160
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 51-70
Chemical type: Peptide from protein
Sequence: PPSTQTLKLIETHLRTIPSH
Position: 51-70
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 51-70
Chemical type: Peptide from protein
Sequence: PPSTQTLKLIETHLRTIPSH
Position: 51-70
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 152-157
Chemical type: Peptide from protein
Sequence: IFFILE
Position: 152-157
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
MHC allele types: 341 91 333 89 339 330 90 327 88
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 152-157
Chemical type: Peptide from protein
Sequence: IFFILE
Position: 152-157
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 158-173
Chemical type: Peptide from protein
Sequence: ITDNPYMTSIPVNAFQ
Position: 158-173
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 158-173
Chemical type: Peptide from protein
Sequence: ITDNPYMTSIPVNAFQ
Position: 158-173
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 171-186
Chemical type: Peptide from protein
Sequence: AFQGLCNETLTLKLYN
Position: 171-186
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 171-186
Chemical type: Peptide from protein
Sequence: AFQGLCNETLTLKLYN
Position: 171-186
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 183-198
Chemical type: Peptide from protein
Sequence: KLYNNGFTSVQGYAFN
Position: 183-198
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 183-198
Chemical type: Peptide from protein
Sequence: KLYNNGFTSVQGYAFN
Position: 183-198
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 195-210
Chemical type: Peptide from protein
Sequence: YAFNGTKLDAVYLNKN
Position: 195-210
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 195-210
Chemical type: Peptide from protein
Sequence: YAFNGTKLDAVYLNKN
Position: 195-210
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 221-240
Chemical type: Peptide from protein
Sequence: FGGVYSGPSLLDVSQTSVTA
Position: 221-240
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 221-240
Chemical type: Peptide from protein
Sequence: FGGVYSGPSLLDVSQTSVTA
Position: 221-240
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 237-252
Chemical type: Peptide from protein
Sequence: SVTALPSKGLEHLKEL
Position: 237-252
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 237-252
Chemical type: Peptide from protein
Sequence: SVTALPSKGLEHLKEL
Position: 237-252
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 248-283
Chemical type: Peptide from protein
Sequence: HLKELIARNTWTLKKL
Position: 248-263
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 248-283
Chemical type: Peptide from protein
Sequence: HLKELIARNTWTLKKL
Position: 248-263
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
MHC allele types: 341 91 333 89
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 261-280
Chemical type: Peptide from protein
Sequence: KKLPLSLSFLHLTRADLSYP
Position: 261-280
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 261-280
Chemical type: Peptide from protein
Sequence: KKLPLSLSFLHLTRADLSYP
Position: 261-280
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 271-290
Chemical type: Peptide from protein
Sequence: HLTRADLSYPSHCCAFKNQK
Position: 271-290
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 271-290
Chemical type: Peptide from protein
Sequence: HLTRADLSYPSHCCAFKNQK
Position: 271-290
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
MHC allele types: 341 91 333 89
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 281-300
Chemical type: Peptide from protein
Sequence: SHCCAFKNQKKIRGILESLM
Position: 281-300
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 281-300
Chemical type: Peptide from protein
Sequence: SHCCAFKNQKKIRGILESLM
Position: 281-300
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 291-310
Chemical type: Peptide from protein
Sequence: KIRGILESLMCNESSMQSLR
Position: 291-310
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 291-310
Chemical type: Peptide from protein
Sequence: KIRGILESLMCNESSMQSLR
Position: 291-310
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 302-320
Chemical type: Peptide from protein
Sequence: NESSMQSLRQRKSVNALNS
Position: 302-320
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 302-320
Chemical type: Peptide from protein
Sequence: NESSMQSLRQRKSVNALNS
Position: 302-320
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
MHC allele types: 339 89 350 86
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 321-340
Chemical type: Peptide from protein
Sequence: PLHQEYEENLGDSIVGYKEK
Position: 321-340
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 321-340
Chemical type: Peptide from protein
Sequence: PLHQEYEENLGDSIVGYKEK
Position: 321-340
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 331-350
Chemical type: Peptide from protein
Sequence: GDSIVGYKEKSKFQDTHNNA
Position: 331-350
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 331-350
Chemical type: Peptide from protein
Sequence: GDSIVGYKEKSKFQDTHNNA
Position: 331-350
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 361-376
Chemical type: Peptide from protein
Sequence: DEIIGFGQELKNPQEE
Position: 361-376
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 361-376
Chemical type: Peptide from protein
Sequence: DEIIGFGQELKNPQEE
Position: 361-376
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 367-386
Chemical type: Peptide from protein
Sequence: GQELKNPQEETLQAFDSHYD
Position: 367-386
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 367-386
Chemical type: Peptide from protein
Sequence: GQELKNPQEETLQAFDSHYD
Position: 367-386
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 377-395
Chemical type: Peptide from protein
Sequence: TLQAFDSHYDYTICGDSED
Position: 377-395
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 377-395
Chemical type: Peptide from protein
Sequence: TLQAFDSHYDYTICGDSED
Position: 377-395
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
MHC allele types: 341 91 333 89
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 396-414
Chemical type: Peptide from protein
Sequence: MVCTPKSDEFNPCEDIMGY
Position: 396-414
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R 396-414
Chemical type: Peptide from protein
Sequence: MVCTPKSDEFNPCEDIMGY
Position: 396-414
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo