Reference: Aziz Alami Chentoufi; Xiuli Zhang; Kasper Lamberth; Gargi Dasgupta; Ilham Bettahi; Alex Nguyen; Michelle Wu; Xiaoming Zhu; Amir Mohebbi; Søren Buus; Steven L Wechsler; Anthony B Nesburn; Lbachir BenMohamed. "HLA-A*0201-restricted CD8+ cytotoxic T lymphocyte epitopes identified from herpes simplex virus glycoprotein D." Journal of immunology (Baltimore, Md. : 1950) (2008).

Epitope: gD<sub>-18 to -10</sub>
Chemical type: Peptide from protein
Sequence: RLGAVILFV
Position: 7-15
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>-18 to -10</sub>
Chemical type: Peptide from protein
Sequence: RLGAVILFV
Position: 7-15
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>-18 to -10</sub>
Chemical type: Peptide from protein
Sequence: RLGAVILFV
Position: 7-15
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Negative
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>-18 to -10</sub>
Chemical type: Peptide from protein
Sequence: RLGAVILFV
Position: 7-15
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Negative
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>-18 to -10</sub>
Chemical type: Peptide from protein
Sequence: RLGAVILFV
Position: 7-15
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>-18 to -10</sub>
Chemical type: Peptide from protein
Sequence: RLGAVILFV
Position: 7-15
Source molecule (GenBank): Q69091.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 62.0

Epitope: gD<sub>-13 to -15</sub>
Chemical type: Peptide from protein
Sequence: ILFVVIVGL
Position: 12-20
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>-13 to -15</sub>
Chemical type: Peptide from protein
Sequence: ILFVVIVGL
Position: 12-20
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>-13 to -15</sub>
Chemical type: Peptide from protein
Sequence: ILFVVIVGL
Position: 12-20
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Negative
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>-13 to -15</sub>
Chemical type: Peptide from protein
Sequence: ILFVVIVGL
Position: 12-20
Source molecule (GenBank): Q69091.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: gD<sub>-11 to -2</sub>
Chemical type: Peptide from protein
Sequence: AVVIVGLHGV
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>-11 to -2</sub>
Chemical type: Peptide from protein
Sequence: AVVIVGLHGV
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>-11 to -2</sub>
Chemical type: Peptide from protein
Sequence: AVVIVGLHGV
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>-11 to -2</sub>
Chemical type: Peptide from protein
Sequence: AVVIVGLHGV
Assay category: TCell
Result: Negative
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>-11 to -2</sub>
Chemical type: Peptide from protein
Sequence: AVVIVGLHGV
Assay category: TCell
Result: Negative
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>-11 to -2</sub>
Chemical type: Peptide from protein
Sequence: AVVIVGLHGV
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: gD<sub>53-61</sub>
Chemical type: Peptide from protein
Sequence: SLPITVYYA
Position: 77-85
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>53-61</sub>
Chemical type: Peptide from protein
Sequence: SLPITVYYA
Position: 77-85
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>53-61</sub>
Chemical type: Peptide from protein
Sequence: SLPITVYYA
Position: 77-85
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>53-61</sub>
Chemical type: Peptide from protein
Sequence: SLPITVYYA
Position: 77-85
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>53-61</sub>
Chemical type: Peptide from protein
Sequence: SLPITVYYA
Position: 77-85
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive-High
Host:  18-63 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>53-61</sub>
Chemical type: Peptide from protein
Sequence: SLPITVYYA
Position: 77-85
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>53-61</sub>
Chemical type: Peptide from protein
Sequence: SLPITVYYA
Position: 77-85
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>53-61</sub>
Chemical type: Peptide from protein
Sequence: SLPITVYYA
Position: 77-85
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>53-61</sub>
Chemical type: Peptide from protein
Sequence: SLPITVYYA
Position: 77-85
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>53-61</sub>
Chemical type: Peptide from protein
Sequence: SLPITVYYA
Position: 77-85
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>53-61</sub>
Chemical type: Peptide from protein
Sequence: SLPITVYYA
Position: 77-85
Source molecule (GenBank): Q69091.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 20.0

Epitope: gD<sub>70-78</sub>
Chemical type: Peptide from protein
Sequence: VLLNAPSEA
Position: 94-102
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>70-78</sub>
Chemical type: Peptide from protein
Sequence: VLLNAPSEA
Position: 94-102
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>70-78</sub>
Chemical type: Peptide from protein
Sequence: VLLNAPSEA
Position: 94-102
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Negative
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>70-78</sub>
Chemical type: Peptide from protein
Sequence: VLLNAPSEA
Position: 94-102
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>70-78</sub>
Chemical type: Peptide from protein
Sequence: VLLNAPSEA
Position: 94-102
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>70-78</sub>
Chemical type: Peptide from protein
Sequence: VLLNAPSEA
Position: 94-102
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>70-78</sub>
Chemical type: Peptide from protein
Sequence: VLLNAPSEA
Position: 94-102
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>70-78</sub>
Chemical type: Peptide from protein
Sequence: VLLNAPSEA
Position: 94-102
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>70-78</sub>
Chemical type: Peptide from protein
Sequence: VLLNAPSEA
Position: 94-102
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>70-78</sub>
Chemical type: Peptide from protein
Sequence: VLLNAPSEA
Position: 94-102
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>70-78</sub>
Chemical type: Peptide from protein
Sequence: VLLNAPSEA
Position: 94-102
Source molecule (GenBank): Q69091.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 19.0

Epitope: gD<sub>95-103</sub>
Chemical type: Peptide from protein
Sequence: NLTIAWPRM
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>95-103</sub>
Chemical type: Peptide from protein
Sequence: NLTIAWPRM
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>95-103</sub>
Chemical type: Peptide from protein
Sequence: NLTIAWPRM
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>95-103</sub>
Chemical type: Peptide from protein
Sequence: NLTIAWPRM
Assay category: TCell
Result: Negative
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>95-103</sub>
Chemical type: Peptide from protein
Sequence: NLTIAWPRM
Assay category: TCell
Result: Negative
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>95-103</sub>
Chemical type: Peptide from protein
Sequence: NLTIAWPRM
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: gD<sub>153-161</sub>
Chemical type: Peptide from protein
Sequence: LMHAPAFET
Position: 177-185
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Negative
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>153-161</sub>
Chemical type: Peptide from protein
Sequence: LMHAPAFET
Position: 177-185
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>153-161</sub>
Chemical type: Peptide from protein
Sequence: LMHAPAFET
Position: 177-185
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>153-161</sub>
Chemical type: Peptide from protein
Sequence: LMHAPAFET
Position: 177-185
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>153-161</sub>
Chemical type: Peptide from protein
Sequence: LMHAPAFET
Position: 177-185
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Negative
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>153-161</sub>
Chemical type: Peptide from protein
Sequence: LMHAPAFET
Position: 177-185
Source molecule (GenBank): Q69091.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 2002.0

Epitope: gD<sub>224-232</sub>
Chemical type: Peptide from protein
Sequence: FIPENQRTV
Position: 248-256
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>224-232</sub>
Chemical type: Peptide from protein
Sequence: FIPENQRTV
Position: 248-256
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>224-232</sub>
Chemical type: Peptide from protein
Sequence: FIPENQRTV
Position: 248-256
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Negative
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>224-232</sub>
Chemical type: Peptide from protein
Sequence: FIPENQRTV
Position: 248-256
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>224-232</sub>
Chemical type: Peptide from protein
Sequence: FIPENQRTV
Position: 248-256
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Negative
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>224-232</sub>
Chemical type: Peptide from protein
Sequence: FIPENQRTV
Position: 248-256
Source molecule (GenBank): Q69091.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 4218.0

Epitope: gD<sub>253-261</sub>
Chemical type: Peptide from protein
Sequence: LLPPELSET
Position: 277-285
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>253-261</sub>
Chemical type: Peptide from protein
Sequence: LLPPELSET
Position: 277-285
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>253-261</sub>
Chemical type: Peptide from protein
Sequence: LLPPELSET
Position: 277-285
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Negative
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>253-261</sub>
Chemical type: Peptide from protein
Sequence: LLPPELSET
Position: 277-285
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>253-261</sub>
Chemical type: Peptide from protein
Sequence: LLPPELSET
Position: 277-285
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Negative
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>253-261</sub>
Chemical type: Peptide from protein
Sequence: LLPPELSET
Position: 277-285
Source molecule (GenBank): Q69091.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 4891.0

Epitope: gD<sub>278-286</sub>
Chemical type: Peptide from protein
Sequence: ALLEDPVGT
Position: 302-310
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>278-286</sub>
Chemical type: Peptide from protein
Sequence: ALLEDPVGT
Position: 302-310
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>278-286</sub>
Chemical type: Peptide from protein
Sequence: ALLEDPVGT
Position: 302-310
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>278-286</sub>
Chemical type: Peptide from protein
Sequence: ALLEDPVGT
Position: 302-310
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>278-286</sub>
Chemical type: Peptide from protein
Sequence: ALLEDPVGT
Position: 302-310
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>278-286</sub>
Chemical type: Peptide from protein
Sequence: ALLEDPVGT
Position: 302-310
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>278-286</sub>
Chemical type: Peptide from protein
Sequence: ALLEDPVGT
Position: 302-310
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>278-286</sub>
Chemical type: Peptide from protein
Sequence: ALLEDPVGT
Position: 302-310
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: gD<sub>278-286</sub>
Chemical type: Peptide from protein
Sequence: ALLEDPVGT
Position: 302-310
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>278-286</sub>
Chemical type: Peptide from protein
Sequence: ALLEDPVGT
Position: 302-310
Source molecule (GenBank): Q69091.1
Assay category: TCell
Result: Positive
Host:  18-63 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: gD<sub>278-286</sub>
Chemical type: Peptide from protein
Sequence: ALLEDPVGT
Position: 302-310
Source molecule (GenBank): Q69091.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 28.0