Reference: Jenny Bostrom; Shang-Fan Yu; David Kan; Brent A Appleton; Chingwei V Lee; Karen Billeci; Wenyan Man; Franklin Peale; Sarajane Ross; Christian Wiesmann; Germaine Fuh. "Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site." Science (New York, N.Y.) (2009).

Epitope: Epitope of bH1 Fab on HER2
Chemical type: Discontinuous protein residues
Discontinuous residues: P579, E580, D582, Q583, K591, D592, P593, P594, F595, P601, K615, A622, C623, Q624, P625, C626, P627
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: Epitope of bH1 Fab on HER2
Chemical type: Discontinuous protein residues
Discontinuous residues: P579, E580, D582, Q583, K591, D592, P593, P594, F595, P601, K615, A622, C623, Q624, P625, C626, P627
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive
Quantitative measurement: 300.0

Epitope: Epitope of bH1 Fab on HER2
Chemical type: Discontinuous protein residues
Discontinuous residues: P579, E580, D582, Q583, K591, D592, P593, P594, F595, P601, K615, A622, C623, Q624, P625, C626, P627
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 1000.0

Epitope: Epitope of bH1 Fab on HER2
Chemical type: Discontinuous protein residues
Discontinuous residues: P579, E580, D582, Q583, K591, D592, P593, P594, F595, P601, K615, A622, C623, Q624, P625, C626, P627
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: Epitope of bH1 Fab on HER2
Chemical type: Discontinuous protein residues
Discontinuous residues: P579, E580, D582, Q583, K591, D592, P593, P594, F595, P601, K615, A622, C623, Q624, P625, C626, P627
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive
Quantitative measurement: 26.0

Epitope: Epitope of bH1 Fab on HER2
Chemical type: Discontinuous protein residues
Discontinuous residues: P579, E580, D582, Q583, K591, D592, P593, P594, F595, P601, K615, A622, C623, Q624, P625, C626, P627
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.9

Epitope: Epitope of bH1 Fab on VEGF A
Chemical type: Discontinuous protein residues
Discontinuous residues: F43, M44, Y71, K74, M107, R108, I109, K110, P111, H112, Q113, G114, Q115, H116, I117, G118, E119
Source molecule (GenBank): P15692.2
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 1000.0

Epitope: Epitope of bH1 Fab on VEGF A
Chemical type: Discontinuous protein residues
Discontinuous residues: F43, M44, Y71, K74, M107, R108, I109, K110, P111, H112, Q113, G114, Q115, H116, I117, G118, E119
Source molecule (GenBank): P15692.2
Assay category: BCell
Result: Positive

Epitope: Epitope of bH1 Fab on VEGF A
Chemical type: Discontinuous protein residues
Discontinuous residues: F43, M44, Y71, K74, M107, R108, I109, K110, P111, H112, Q113, G114, Q115, H116, I117, G118, E119
Source molecule (GenBank): P15692.2
Assay category: BCell
Result: Positive

Epitope: Epitope of bH1 Fab on VEGF A
Chemical type: Discontinuous protein residues
Discontinuous residues: F43, M44, Y71, K74, M107, R108, I109, K110, P111, H112, Q113, G114, Q115, H116, I117, G118, E119
Source molecule (GenBank): P15692.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2.6

Epitope: Epitope of bH1 Fab on VEGF A
Chemical type: Discontinuous protein residues
Discontinuous residues: F43, M44, Y71, K74, M107, R108, I109, K110, P111, H112, Q113, G114, Q115, H116, I117, G118, E119
Source molecule (GenBank): P15692.2
Assay category: BCell
Result: Positive
Quantitative measurement: 300.0