Reference: Anna D Koromyslova; Grant S Hansman. "Nanobodies targeting norovirus capsid reveal functional epitopes and potential mechanisms of neutralization." PLoS pathogens (2017).

Epitope: Epitope of nanobody Nano-4 on GII.17 Kawasaki P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: L474, R476, R484, T485, L486, E488, D518, V521, N522, F524, Y525, S526, L527, A528
Source molecule (GenBank): BAR42289.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-4 on GII.17 Kawasaki P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: L474, R476, R484, T485, L486, E488, D518, V521, N522, F524, Y525, S526, L527, A528
Source molecule (GenBank): BAR42289.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of nanobody Nano-4 on GII.17 Kawasaki P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: L474, R476, R484, T485, L486, E488, D518, V521, N522, F524, Y525, S526, L527, A528
Source molecule (GenBank): BAR42289.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of nanobody Nano-4 on GII.17 Kawasaki P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: L474, R476, R484, T485, L486, E488, D518, V521, N522, F524, Y525, S526, L527, A528
Source molecule (GenBank): BAR42289.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of nanobody Nano-4 on GII.17 Kawasaki P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: L474, R476, R484, T485, L486, E488, D518, V521, N522, F524, Y525, S526, L527, A528
Source molecule (GenBank): BAR42289.1
Assay category: BCell
Result: Negative

Epitope: Epitope of nanobody Nano-4 on GII.17 Kawasaki P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: L474, R476, R484, T485, L486, E488, D518, V521, N522, F524, Y525, S526, L527, A528
Source molecule (GenBank): BAR42289.1
Assay category: BCell
Result: Positive
Quantitative measurement: 35.0

Epitope: Epitope of nanobody Nano-4 on GII.17 Kawasaki P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: L474, R476, R484, T485, L486, E488, D518, V521, N522, F524, Y525, S526, L527, A528
Source molecule (GenBank): BAR42289.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-4 on GII.17 Kawasaki P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: L474, R476, R484, T485, L486, E488, D518, V521, N522, F524, Y525, S526, L527, A528
Source molecule (GenBank): BAR42289.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.72

Epitope: Epitope of nanobody Nano-27 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: L482, R484, G491, R492, T493, L494, E496, D526, Y533, T534, L535, A536, P537
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Negative
Quantitative measurement: 9.5

Epitope: Epitope of nanobody Nano-27 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: L482, R484, G491, R492, T493, L494, E496, D526, Y533, T534, L535, A536, P537
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-27 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: L482, R484, G491, R492, T493, L494, E496, D526, Y533, T534, L535, A536, P537
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.68

Epitope: Epitope of nanobody Nano-27 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: L482, R484, G491, R492, T493, L494, E496, D526, Y533, T534, L535, A536, P537
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-27 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: L482, R484, G491, R492, T493, L494, E496, D526, Y533, T534, L535, A536, P537
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Negative

Epitope: Epitope of nanobody Nano-14 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: H298, R299, G300, Q333, H358, E359, V361, A363, S379, T380, W381, E382, A400, S401, D403, K449; B: E359, W381, E382, T383, K449
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-14 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: H298, R299, G300, Q333, H358, E359, V361, A363, S379, T380, W381, E382, A400, S401, D403, K449; B: E359, W381, E382, T383, K449
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-14 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: H298, R299, G300, Q333, H358, E359, V361, A363, S379, T380, W381, E382, A400, S401, D403, K449; B: E359, W381, E382, T383, K449
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.4

Epitope: Epitope of nanobody Nano-14 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: H298, R299, G300, Q333, H358, E359, V361, A363, S379, T380, W381, E382, A400, S401, D403, K449; B: E359, W381, E382, T383, K449
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-14 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: H298, R299, G300, Q333, H358, E359, V361, A363, S379, T380, W381, E382, A400, S401, D403, K449; B: E359, W381, E382, T383, K449
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.7

Epitope: Epitope of nanobody Nano-32 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: D247, V248, F445, R492, V516, A517, P518, T519, N520; B: R287, K289, G312, T313, P314, D316, P317, T318, T343, N344, T345, P391
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-32 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: D247, V248, F445, R492, V516, A517, P518, T519, N520; B: R287, K289, G312, T313, P314, D316, P317, T318, T343, N344, T345, P391
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-32 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: D247, V248, F445, R492, V516, A517, P518, T519, N520; B: R287, K289, G312, T313, P314, D316, P317, T318, T343, N344, T345, P391
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive
Quantitative measurement: 60.0

Epitope: Epitope of nanobody Nano-32 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: D247, V248, F445, R492, V516, A517, P518, T519, N520; B: R287, K289, G312, T313, P314, D316, P317, T318, T343, N344, T345, P391
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-32 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: D247, V248, F445, R492, V516, A517, P518, T519, N520; B: R287, K289, G312, T313, P314, D316, P317, T318, T343, N344, T345, P391
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.19

Epitope: Epitope of nanobody Nano-85 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: F434, L477, S478, E496, F525, D526, S527, W528, V529, N530, F532, Y533, T534, L535, A536
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of nanobody Nano-85 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: F434, L477, S478, E496, F525, D526, S527, W528, V529, N530, F532, Y533, T534, L535, A536
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of nanobody Nano-85 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: F434, L477, S478, E496, F525, D526, S527, W528, V529, N530, F532, Y533, T534, L535, A536
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of nanobody Nano-85 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: F434, L477, S478, E496, F525, D526, S527, W528, V529, N530, F532, Y533, T534, L535, A536
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-85 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: F434, L477, S478, E496, F525, D526, S527, W528, V529, N530, F532, Y533, T534, L535, A536
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-85 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: F434, L477, S478, E496, F525, D526, S527, W528, V529, N530, F532, Y533, T534, L535, A536
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-85 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: F434, L477, S478, E496, F525, D526, S527, W528, V529, N530, F532, Y533, T534, L535, A536
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of nanobody Nano-85 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: F434, L477, S478, E496, F525, D526, S527, W528, V529, N530, F532, Y533, T534, L535, A536
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of nanobody Nano-85 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: F434, L477, S478, E496, F525, D526, S527, W528, V529, N530, F532, Y533, T534, L535, A536
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of nanobody Nano-85 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: F434, L477, S478, E496, F525, D526, S527, W528, V529, N530, F532, Y533, T534, L535, A536
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.3

Epitope: Epitope of nanobody Nano-85 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: F434, L477, S478, E496, F525, D526, S527, W528, V529, N530, F532, Y533, T534, L535, A536
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-85 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: F434, L477, S478, E496, F525, D526, S527, W528, V529, N530, F532, Y533, T534, L535, A536
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-85 on GII.10 Vietnam 026 P domain
Chemical type: Discontinuous protein residues
Discontinuous residues: F434, L477, S478, E496, F525, D526, S527, W528, V529, N530, F532, Y533, T534, L535, A536
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-26 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I231, P488, E489, T490, G491, Y522; B: S224, K225, G270, E271, L272, Q273, G274, T276, E319, L325, Y470, Q471, E472, S473, P475, R501
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-26 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I231, P488, E489, T490, G491, Y522; B: S224, K225, G270, E271, L272, Q273, G274, T276, E319, L325, Y470, Q471, E472, S473, P475, R501
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.2

Epitope: Epitope of nanobody Nano-26 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I231, P488, E489, T490, G491, Y522; B: S224, K225, G270, E271, L272, Q273, G274, T276, E319, L325, Y470, Q471, E472, S473, P475, R501
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-26 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I231, P488, E489, T490, G491, Y522; B: S224, K225, G270, E271, L272, Q273, G274, T276, E319, L325, Y470, Q471, E472, S473, P475, R501
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-26 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I231, P488, E489, T490, G491, Y522; B: S224, K225, G270, E271, L272, Q273, G274, T276, E319, L325, Y470, Q471, E472, S473, P475, R501
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-26 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I231, P488, E489, T490, G491, Y522; B: S224, K225, G270, E271, L272, Q273, G274, T276, E319, L325, Y470, Q471, E472, S473, P475, R501
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-26 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I231, P488, E489, T490, G491, Y522; B: S224, K225, G270, E271, L272, Q273, G274, T276, E319, L325, Y470, Q471, E472, S473, P475, R501
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of nanobody Nano-26 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I231, P488, E489, T490, G491, Y522; B: S224, K225, G270, E271, L272, Q273, G274, T276, E319, L325, Y470, Q471, E472, S473, P475, R501
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-26 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I231, P488, E489, T490, G491, Y522; B: S224, K225, G270, E271, L272, Q273, G274, T276, E319, L325, Y470, Q471, E472, S473, P475, R501
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.3

Epitope: Epitope of nanobody Nano-26 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I231, P488, E489, T490, G491, Y522; B: S224, K225, G270, E271, L272, Q273, G274, T276, E319, L325, Y470, Q471, E472, S473, P475, R501
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nano-26 on GII.10 Vietnam 026 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: I231, P488, E489, T490, G491, Y522; B: S224, K225, G270, E271, L272, Q273, G274, T276, E319, L325, Y470, Q471, E472, S473, P475, R501
Source molecule (GenBank): AAT12445.1
Assay category: BCell
Result: Positive