Reference: Wolfgang Schönharting; Tim Roehnisch; Mehdi Manoochehri; Jan Christoph; Marie Sieger; Mauro Nogueira; Mari Carmen Martos-Contreras; Meik Kunz. "Improved Survival of a HER2-Positive Metastatic Breast Cancer Patient Following a Personalized Peptide Immunization." Vaccines (2023).

Epitope: GLDEAIRKV
Chemical type: Peptide from protein
Sequence: GLDEAIRKV
Position: 109-117
Source molecule (GenBank): Q8WU03.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: QIWDKILSV
Chemical type: Peptide from protein
Sequence: QIWDKILSV
Position: 136-144
Source molecule (GenBank): Q13268.4
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GLISELKLA
Chemical type: Peptide from protein
Sequence: GLISELKLA
Position: 8-16
Source molecule (GenBank): F2Z3M3.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: IPAPPLSKV
Chemical type: Peptide from protein
Sequence: IPAPPLSKV
Position: 28-36
Source molecule (GenBank): P80188-2.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KSMDIVLTV
Chemical type: Peptide from protein
Sequence: KSMDIVLTV
Position: 5141-5149
Source molecule (GenBank): Q9HC84.3
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPNQAQMRI
Chemical type: Peptide from protein
Sequence: MPNQAQMRI
Position: 75-83
Source molecule (GenBank): J3KTI5.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TYLPTNASLSF
Chemical type: Peptide from protein
Sequence: TYLPTNASLSF
Position: 63-73
Source molecule (GenBank): J3QLU9.1
Assay category: TCell
Result: Positive
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KIADFGWSV
Chemical type: Peptide from protein
Sequence: KIADFGWSV
Position: 178-186
Source molecule (GenBank): Q5Y191.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TTYIFRLAAKNRAG
Chemical type: Peptide from protein
Sequence: TTYIFRLAAKNRAG
Position: 532-545
Source molecule (GenBank): H0Y6Z7.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NEKVIEHIM
Chemical type: Peptide from protein
Sequence: NEKVIEHIM
Position: 55-63
Source molecule (GenBank): P06702.1
Assay category: TCell
Result: Positive
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KYSLIKGNF
Chemical type: Peptide from protein
Sequence: KYSLIKGNF
Position: 18-26
Source molecule (GenBank): P05109.1
Assay category: TCell
Result: Positive
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TLFDYEVRL
Chemical type: Peptide from protein
Sequence: TLFDYEVRL
Position: 70-78
Source molecule (GenBank): Q96T88-2.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PFLQASPHF
Chemical type: Peptide from protein
Sequence: PFLQASPHF
Position: 426-434
Source molecule (GenBank): Q86UY5.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: EDKKIDFSEFLSLLGDI
Chemical type: Peptide from protein
Sequence: EDKKIDFSEFLSLLGDI
Position: 66-82
Source molecule (GenBank): Q86SG5.3
Assay category: TCell
Result: Positive
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MEESHLNSNPYFWPSI
Chemical type: Peptide, no natural source
Sequence: MEESHLNSNPYFWPSI
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SKMENPGSV
Chemical type: Peptide, no natural source
Sequence: SKMENPGSV
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAVAHMIEA
Chemical type: Peptide, no natural source
Sequence: AAVAHMIEA
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CAHNASGYF
Chemical type: Peptide, no natural source
Sequence: CAHNASGYF
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: EETSNLSAL
Chemical type: Peptide, no natural source
Sequence: EETSNLSAL
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SEVLFIATA
Chemical type: Peptide, no natural source
Sequence: SEVLFIATA
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NALQLGLMV
Chemical type: Peptide, no natural source
Sequence: NALQLGLMV
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: YKSDLVQIY
Chemical type: Peptide, no natural source
Sequence: YKSDLVQIY
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RHHSKRSQR
Chemical type: Peptide, no natural source
Sequence: RHHSKRSQR
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SAARASIEL
Chemical type: Peptide, no natural source
Sequence: SAARASIEL
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KCVNEDLKI
Chemical type: Peptide, no natural source
Sequence: KCVNEDLKI
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: QRSSHYHE
Chemical type: Peptide, no natural source
Sequence: QRSSHYHE
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DEDEIKWWW
Chemical type: Peptide, no natural source
Sequence: DEDEIKWWW
Assay category: TCell
Result: Positive
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NLEGVETQL
Chemical type: Peptide, no natural source
Sequence: NLEGVETQL
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KTISLPPPI
Chemical type: Peptide, no natural source
Sequence: KTISLPPPI
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KYIQESQALAKRSCGLFQKLGEYYLQNAFL
Chemical type: Peptide from protein
Sequence: KYIQESQALAKRSCGLFQKLGEYYLQNAFL
Position: 403-432
Source molecule (GenBank): P02771.1
Assay category: TCell
Result: Positive
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AYTKKAPQL
Chemical type: Peptide from protein
Sequence: AYTKKAPQL
Position: 434-442
Source molecule (GenBank): P02771.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KYIQESQAL
Chemical type: Peptide from protein
Sequence: KYIQESQAL
Position: 403-411
Source molecule (GenBank): P02771.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: EYYLQNAFL
Chemical type: Peptide from protein
Sequence: EYYLQNAFL
Position: 424-432
Source molecule (GenBank): P02771.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PLFQVPEPV
Chemical type: Peptide from protein
Sequence: PLFQVPEPV
Position: 137-145
Source molecule (GenBank): P02771.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KVNFTEIQKL
Chemical type: Peptide from protein
Sequence: KVNFTEIQKL
Position: 249-258
Source molecule (GenBank): P02771.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ILYPGGNKY
Chemical type: Peptide from protein
Sequence: ILYPGGNKY
Position: 66-74
Source molecule (GenBank): O94907.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ALGAAGATRV
Chemical type: Peptide from protein
Sequence: ALGAAGATRV
Position: 3-12
Source molecule (GenBank): O94907.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RLLILILSII
Chemical type: Peptide from protein
Sequence: RLLILILSII
Position: 65-74
Source molecule (GenBank): O60732-2
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KVWVQEHYL
Chemical type: Peptide from protein
Sequence: KVWVQEHYL
Position: 1046-1054
Source molecule (GenBank): O60732.3
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ILAVDGVLSV
Chemical type: Peptide from protein
Sequence: ILAVDGVLSV
Position: 242-251
Source molecule (GenBank): Q8IWU4-2
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HETYGHKTPY
Chemical type: Peptide from protein
Sequence: HETYGHKTPY
Position: 71-80
Source molecule (GenBank): D6RC73.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LEQEIATY
Chemical type: Peptide from protein
Sequence: LEQEIATY
Position: 132-139
Source molecule (GenBank): Q8N1A0.1
Assay category: TCell
Result: Positive
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: VDLIVEYEAFPKPE
Chemical type: Peptide from protein
Sequence: VDLIVEYEAFPKPE
Position: 331-344
Source molecule (GenBank): P10721-2
Assay category: TCell
Result: Positive
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: IHREDEDEIKWWWARLN
Chemical type: Peptide, no natural source
Sequence: IHREDEDEIKWWWARLN
Assay category: TCell
Result: Positive
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: STKYSHKSPQLSVHVTD
Chemical type: Peptide, no natural source
Sequence: STKYSHKSPQLSVHVTD
Assay category: TCell
Result: Positive
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ATYSGAGYYLDLSIT
Chemical type: Peptide, no natural source
Sequence: ATYSGAGYYLDLSIT
Assay category: TCell
Result: Positive
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HGSSFFLLILKRDSAFI
Chemical type: Peptide, no natural source
Sequence: HGSSFFLLILKRDSAFI
Assay category: TCell
Result: Positive
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TASQRFIELGADIKRVK
Chemical type: Peptide, no natural source
Sequence: TASQRFIELGADIKRVK
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DAVIVKLEI
Chemical type: Peptide from protein
Sequence: DAVIVKLEI
Position: 279-287
Source molecule (GenBank): B4DFN3.1
Assay category: TCell
Result: Positive
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: YYLDLSTTR
Chemical type: Peptide, no natural source
Sequence: YYLDLSTTR
Assay category: TCell
Result: Positive
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KLLLAEKAV
Chemical type: Peptide, no natural source
Sequence: KLLLAEKAV
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RTPLSALCV
Chemical type: Peptide, no natural source
Sequence: RTPLSALCV
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LLGGNALKF
Chemical type: Peptide, no natural source
Sequence: LLGGNALKF
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: WVHCAHNAS
Chemical type: Peptide, no natural source
Sequence: WVHCAHNAS
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KVVEFLAML
Chemical type: Peptide from protein
Sequence: KVVEFLAML
Position: 150-158
Source molecule (GenBank): O60732-2
Assay category: TCell
Result: Positive
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NLMEQPIKV
Chemical type: Peptide from protein
Sequence: NLMEQPIKV
Position: 5-13
Source molecule (GenBank): C9JTX4.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CNCTRSLLR
Chemical type: Peptide, no natural source
Sequence: CNCTRSLLR
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: IYLEKLKTI
Chemical type: Peptide from protein
Sequence: IYLEKLKTI
Position: 1083-1091
Source molecule (GenBank): Q15149-5.1
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: WTLHNLSDV
Chemical type: Peptide, no natural source
Sequence: WTLHNLSDV
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GEIWVHCAH
Chemical type: Peptide, no natural source
Sequence: GEIWVHCAH
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LSTWDQPKK
Chemical type: Peptide, no natural source
Sequence: LSTWDQPKK
Assay category: TCell
Result: Negative
MHC allele types: 143 215 252 40 1 8 417 355 542 818
Host: F 43 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated