Reference: Nathaniel Bloodworth; Wei Chen; Kuniko Hunter; David Patrick; Amy Palubinsky; Elizabeth Phillips; Daniel Roeth; Markus Kalkum; Simon Mallal; Sean Davies; Mingfang Ao; Rocco Moretti; Jens Meiler; David G Harrison. "Posttranslationally modified self-peptides promote hypertension in mouse models." The Journal of clinical investigation (2024).

Epitope: LAGKNLTHI
Chemical type: Peptide from protein
Sequence: LAGKNLTHI
Position: 300-308
Source molecule (GenBank): NP_573517.1
Assay category: TCell
Result: Positive-Low
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: LAGKNLTHI
Chemical type: Peptide from protein
Sequence: LAGKNLTHI
Position: 300-308
Source molecule (GenBank): NP_573517.1
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: LAGKNLTHI
Chemical type: Peptide from protein
Sequence: LAGKNLTHI
Position: 300-308
Source molecule (GenBank): NP_573517.1
Assay category: TCell
Result: Negative
Host: M 12 weeks

Epitope: LAGKNLTHI
Chemical type: Peptide from protein
Sequence: LAGKNLTHI
Position: 300-308
Source molecule (GenBank): NP_573517.1
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD4+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SQNKNAKAM
Chemical type: Peptide from protein
Sequence: SQNKNAKAM
Position: 292-300
Source molecule (GenBank): NP_038695.1
Assay category: TCell
Result: Positive-Low
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SQNKNAKAM
Chemical type: Peptide from protein
Sequence: SQNKNAKAM
Position: 292-300
Source molecule (GenBank): NP_038695.1
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: FSYKKMTIM
Chemical type: Peptide from protein
Sequence: FSYKKMTIM
Position: 66-74
Source molecule (GenBank): NP_064361.2
Assay category: TCell
Result: Positive-Low
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: FSYKKMTIM
Chemical type: Peptide from protein
Sequence: FSYKKMTIM
Position: 66-74
Source molecule (GenBank): NP_064361.2
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: SSSKPVEPL
Chemical type: Peptide from protein
Sequence: SSSKPVEPL
Position: 367-375
Source molecule (GenBank): NP_569723.1
Assay category: TCell
Result: Positive-Low
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SSSKPVEPL
Chemical type: Peptide from protein
Sequence: SSSKPVEPL
Position: 367-375
Source molecule (GenBank): NP_569723.1
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: KAMKIIKHI
Chemical type: Peptide from protein
Sequence: KAMKIIKHI
Position: 298-306
Source molecule (GenBank): NP_038695.1
Assay category: TCell
Result: Positive-Low
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: KAMKIIKHI
Chemical type: Peptide from protein
Sequence: KAMKIIKHI
Position: 298-306
Source molecule (GenBank): NP_038695.1
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: YILKLPLPL
Chemical type: Peptide from protein
Sequence: YILKLPLPL
Position: 42-50
Source molecule (GenBank): NP_031689.1
Assay category: TCell
Result: Positive-Low
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: YILKLPLPL
Chemical type: Peptide from protein
Sequence: YILKLPLPL
Position: 42-50
Source molecule (GenBank): NP_031689.1
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: YILKLPLPL
Chemical type: Peptide from protein
Sequence: YILKLPLPL
Position: 42-50
Source molecule (GenBank): NP_031689.1
Assay category: TCell
Result: Negative
Host: M 12 weeks

Epitope: YILKLPLPL
Chemical type: Peptide from protein
Sequence: YILKLPLPL
Position: 42-50
Source molecule (GenBank): NP_031689.1
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD4+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: AAPDHKVVV
Chemical type: Peptide from protein
Sequence: AAPDHKVVV
Position: 524-532
Source molecule (GenBank): NP_031689.1
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD4+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: AAPDHKVVV
Chemical type: Peptide from protein
Sequence: AAPDHKVVV
Position: 524-532
Source molecule (GenBank): NP_031689.1
Assay category: TCell
Result: Positive-Low
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: AAPDHKVVV
Chemical type: Peptide from protein
Sequence: AAPDHKVVV
Position: 524-532
Source molecule (GenBank): NP_031689.1
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: AAPDHKVVV
Chemical type: Peptide from protein
Sequence: AAPDHKVVV
Position: 524-532
Source molecule (GenBank): NP_031689.1
Assay category: TCell
Result: Negative
Host: M 12 weeks

Epitope: FSLQVKPEI
Chemical type: Peptide from protein
Sequence: FSLQVKPEI
Position: 123-131
Source molecule (GenBank): NP_001160104.1
Assay category: TCell
Result: Positive-Low
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: FSLQVKPEI
Chemical type: Peptide from protein
Sequence: FSLQVKPEI
Position: 123-131
Source molecule (GenBank): NP_001160104.1
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: MQLPSKVVL
Chemical type: Peptide from protein
Sequence: MQLPSKVVL
Position: 17-25
Source molecule (GenBank): NP_775603.2
Assay category: TCell
Result: Positive-Low
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: MQLPSKVVL
Chemical type: Peptide from protein
Sequence: MQLPSKVVL
Position: 17-25
Source molecule (GenBank): NP_775603.2
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: MQLPSKVVL
Chemical type: Peptide from protein
Sequence: MQLPSKVVL
Position: 17-25
Source molecule (GenBank): NP_775603.2
Assay category: TCell
Result: Negative
Host: M 12 weeks

Epitope: MQLPSKVVL
Chemical type: Peptide from protein
Sequence: MQLPSKVVL
Position: 17-25
Source molecule (GenBank): NP_775603.2
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD4+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SVPTHKSSL
Chemical type: Peptide from protein
Sequence: SVPTHKSSL
Position: 252-260
Source molecule (GenBank): NP_766246.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: SVPTHKSSL
Chemical type: Peptide from protein
Sequence: SVPTHKSSL
Position: 252-260
Source molecule (GenBank): NP_766246.1
Assay category: TCell
Result: Positive-Low
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: MADITKSYL
Chemical type: Peptide from protein
Sequence: MADITKSYL
Position: 94-102
Source molecule (GenBank): NP_075944.1
Assay category: TCell
Result: Positive-Low
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: MADITKSYL
Chemical type: Peptide from protein
Sequence: MADITKSYL
Position: 94-102
Source molecule (GenBank): NP_075944.1
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: MADITKSYL
Chemical type: Peptide from protein
Sequence: MADITKSYL
Position: 94-102
Source molecule (GenBank): NP_075944.1
Assay category: TCell
Result: Negative
Host: M 12 weeks

Epitope: MADITKSYL
Chemical type: Peptide from protein
Sequence: MADITKSYL
Position: 94-102
Source molecule (GenBank): NP_075944.1
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD4+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: MMKFNKFSL
Chemical type: Peptide from protein
Sequence: MMKFNKFSL
Position: 201-209
Source molecule (GenBank): NP_064361.2
Assay category: TCell
Result: Positive-Low
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: MMKFNKFSL
Chemical type: Peptide from protein
Sequence: MMKFNKFSL
Position: 201-209
Source molecule (GenBank): NP_064361.2
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: LAGKNLTHI+IsoLG
Chemical type: Peptide from protein
Sequence: LAGKNLTHI
Position: 300-308
Source molecule (GenBank): NP_573517.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: LAGKNLTHI+IsoLG
Chemical type: Peptide from protein
Sequence: LAGKNLTHI
Position: 300-308
Source molecule (GenBank): NP_573517.1
Assay category: TCell
Result: Positive
Host: M 12 weeks

Epitope: LAGKNLTHI+IsoLG
Chemical type: Peptide from protein
Sequence: LAGKNLTHI
Position: 300-308
Source molecule (GenBank): NP_573517.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD4+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: LAGKNLTHI+IsoLG
Chemical type: Peptide from protein
Sequence: LAGKNLTHI
Position: 300-308
Source molecule (GenBank): NP_573517.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SQNKNAKAM+IsoLG
Chemical type: Peptide from protein
Sequence: SQNKNAKAM
Position: 292-300
Source molecule (GenBank): NP_038695.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SQNKNAKAM+IsoLG
Chemical type: Peptide from protein
Sequence: SQNKNAKAM
Position: 292-300
Source molecule (GenBank): NP_038695.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: FSYKKMTIM+IsoLG
Chemical type: Peptide from protein
Sequence: FSYKKMTIM
Position: 66-74
Source molecule (GenBank): NP_064361.2
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: FSYKKMTIM+IsoLG
Chemical type: Peptide from protein
Sequence: FSYKKMTIM
Position: 66-74
Source molecule (GenBank): NP_064361.2
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SSSKPVEPL+IsoLG
Chemical type: Peptide from protein
Sequence: SSSKPVEPL
Position: 367-375
Source molecule (GenBank): NP_569723.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SSSKPVEPL+IsoLG
Chemical type: Peptide from protein
Sequence: SSSKPVEPL
Position: 367-375
Source molecule (GenBank): NP_569723.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: KAMKIIKHI+IsoLG
Chemical type: Peptide from protein
Sequence: KAMKIIKHI
Position: 298-306
Source molecule (GenBank): NP_038695.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: KAMKIIKHI+IsoLG
Chemical type: Peptide from protein
Sequence: KAMKIIKHI
Position: 298-306
Source molecule (GenBank): NP_038695.1
Assay category: TCell
Result: Negative
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: YILKLPLPL+IsoLG
Chemical type: Peptide from protein
Sequence: YILKLPLPL
Position: 42-50
Source molecule (GenBank): NP_031689.1
Assay category: TCell
Result: Positive
Host: M 12 weeks

Epitope: YILKLPLPL+IsoLG
Chemical type: Peptide from protein
Sequence: YILKLPLPL
Position: 42-50
Source molecule (GenBank): NP_031689.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD4+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: YILKLPLPL+IsoLG
Chemical type: Peptide from protein
Sequence: YILKLPLPL
Position: 42-50
Source molecule (GenBank): NP_031689.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: YILKLPLPL+IsoLG
Chemical type: Peptide from protein
Sequence: YILKLPLPL
Position: 42-50
Source molecule (GenBank): NP_031689.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: GSPKQHEVV+IsoLG
Chemical type: Peptide from protein
Sequence: GSPKQHEVV
Position: 8-16
Source molecule (GenBank): NP_035527.3
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GSPKQHEVV+IsoLG
Chemical type: Peptide from protein
Sequence: GSPKQHEVV
Position: 8-16
Source molecule (GenBank): NP_035527.3
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: GSPKQHEVV+IsoLG
Chemical type: Peptide from protein
Sequence: GSPKQHEVV
Position: 8-16
Source molecule (GenBank): NP_035527.3
Assay category: TCell
Result: Positive
Host: M 12 weeks

Epitope: GSPKQHEVV+IsoLG
Chemical type: Peptide from protein
Sequence: GSPKQHEVV
Position: 8-16
Source molecule (GenBank): NP_035527.3
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD4+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: AAPDHKVVV+IsoLG
Chemical type: Peptide from protein
Sequence: AAPDHKVVV
Position: 524-532
Source molecule (GenBank): NP_031689.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: AAPDHKVVV+IsoLG
Chemical type: Peptide from protein
Sequence: AAPDHKVVV
Position: 524-532
Source molecule (GenBank): NP_031689.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: AAPDHKVVV+IsoLG
Chemical type: Peptide from protein
Sequence: AAPDHKVVV
Position: 524-532
Source molecule (GenBank): NP_031689.1
Assay category: TCell
Result: Negative
Host: M 12 weeks

Epitope: AAPDHKVVV+IsoLG
Chemical type: Peptide from protein
Sequence: AAPDHKVVV
Position: 524-532
Source molecule (GenBank): NP_031689.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD4+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: FSLQVKPEI+IsoLG
Chemical type: Peptide from protein
Sequence: FSLQVKPEI
Position: 123-131
Source molecule (GenBank): NP_001160104.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: FSLQVKPEI+IsoLG
Chemical type: Peptide from protein
Sequence: FSLQVKPEI
Position: 123-131
Source molecule (GenBank): NP_001160104.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: MQLPSKVVL+IsoLG
Chemical type: Peptide from protein
Sequence: MQLPSKVVL
Position: 17-25
Source molecule (GenBank): NP_775603.2
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: MQLPSKVVL+IsoLG
Chemical type: Peptide from protein
Sequence: MQLPSKVVL
Position: 17-25
Source molecule (GenBank): NP_775603.2
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: MQLPSKVVL+IsoLG
Chemical type: Peptide from protein
Sequence: MQLPSKVVL
Position: 17-25
Source molecule (GenBank): NP_775603.2
Assay category: TCell
Result: Positive
Host: M 12 weeks

Epitope: MQLPSKVVL+IsoLG
Chemical type: Peptide from protein
Sequence: MQLPSKVVL
Position: 17-25
Source molecule (GenBank): NP_775603.2
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD4+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SVPTHKSSL+IsoLG
Chemical type: Peptide from protein
Sequence: SVPTHKSSL
Position: 252-260
Source molecule (GenBank): NP_766246.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SVPTHKSSL+IsoLG
Chemical type: Peptide from protein
Sequence: SVPTHKSSL
Position: 252-260
Source molecule (GenBank): NP_766246.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: MADITKSYL+IsoLG
Chemical type: Peptide from protein
Sequence: MADITKSYL
Position: 94-102
Source molecule (GenBank): NP_075944.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: MADITKSYL+IsoLG
Chemical type: Peptide from protein
Sequence: MADITKSYL
Position: 94-102
Source molecule (GenBank): NP_075944.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD8+
Tissue: aorta
Culture conditions: Direct Ex Vivo

Epitope: MADITKSYL+IsoLG
Chemical type: Peptide from protein
Sequence: MADITKSYL
Position: 94-102
Source molecule (GenBank): NP_075944.1
Assay category: TCell
Result: Negative
Host: M 12 weeks

Epitope: MADITKSYL+IsoLG
Chemical type: Peptide from protein
Sequence: MADITKSYL
Position: 94-102
Source molecule (GenBank): NP_075944.1
Assay category: TCell
Result: Positive
Host: M 12 weeks
Cell type: T cell CD4+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo