Reference: Toshiyuki Takaki; Michele P Marron; Clayton E Mathews; Stephen T Guttmann; Rita Bottino; Massimo Trucco; Teresa P DiLorenzo; David V Serreze. "HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes." Journal of immunology (Baltimore, Md. : 1950) (2006).

Epitope: mIGRP226–236
Chemical type: Peptide from protein
Sequence: RLFGIDLLWSV
Position: 226-236
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Positive
Host: F 12 weeks
Cell type: T cell
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: mIGRP227–236
Chemical type: Peptide from protein
Sequence: LFGIDLLWSV
Position: 227-236
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Positive
Host: F 12 weeks
Cell type: T cell
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: mIGRP228–236
Chemical type: Peptide from protein
Sequence: FGIDLLWSV
Position: 228-236
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Positive
Host: F 12-13 weeks
Cell type: T cell
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: mIGRP228–236
Chemical type: Peptide from protein
Sequence: FGIDLLWSV
Position: 228-236
Source molecule (GenBank): NP_067306.1
Assay category: MhcBinding
Result: Positive

Epitope: mIGRP265–273
Chemical type: Peptide from protein
Sequence: VLFGLGFAI
Position: 265-273
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Positive
Host: F 12-13 weeks
Cell type: T cell
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: mIGRP265–273
Chemical type: Peptide from protein
Sequence: VLFGLGFAI
Position: 265-273
Source molecule (GenBank): NP_067306.1
Assay category: MhcBinding
Result: Positive

Epitope: mIGRP337–345
Chemical type: Peptide from protein
Sequence: ALIPYCVHM
Position: 337-345
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Positive-Low
Host: F 12-13 weeks
Cell type: T cell
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: mIGRP337–345
Chemical type: Peptide from protein
Sequence: ALIPYCVHM
Position: 337-345
Source molecule (GenBank): NP_067306.1
Assay category: MhcBinding
Result: Positive

Epitope: hIGRP228–236
Chemical type: Peptide from protein
Sequence: LNIDLLWSV
Position: 228-236
Source molecule (GenBank): NP_066999.1
Assay category: TCell
Result: Positive
Host: F 12 weeks
Cell type: T cell
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: hIGRP228–236
Chemical type: Peptide from protein
Sequence: LNIDLLWSV
Position: 228-236
Source molecule (GenBank): NP_066999.1
Assay category: MhcBinding
Result: Positive

Epitope: hIGRP337–345
Chemical type: Peptide from protein
Sequence: AFIPYSVHM
Position: 337-345
Source molecule (GenBank): NP_066999.1
Assay category: TCell
Result: Positive-Low
Host: F 12 weeks
Cell type: T cell
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: hIGRP337–345
Chemical type: Peptide from protein
Sequence: AFIPYSVHM
Position: 337-345
Source molecule (GenBank): NP_066999.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: hIGRP265–273
Chemical type: Peptide from protein
Sequence: VLFGLGFAI
Position: 265-273
Source molecule (GenBank): NP_066999.1
Assay category: MhcBinding
Result: Positive