Reference: Anat Zvi; Shahar Rotem; Erez Bar-Haim; Ofer Cohen; Avigdor Shafferman. "Whole-genome immunoinformatic analysis of F. tularensis: predicted CTL epitopes clustered in hotspots are prone to elicit a T-cell response." PloS one (2011).

Epitope: toxin secretion ABC transporter ATP-binding peptide 20
Chemical type: Peptide from protein
Sequence: TYIFINILL
Position: 136-144
Source molecule (GenBank): YP_514469.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: toxin secretion ABC transporter ATP-binding peptide 21
Chemical type: Peptide from protein
Sequence: TYIFINILLL
Position: 136-145
Source molecule (GenBank): YP_514469.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: toxin secretion ABC transporter ATP-binding peptide 22
Chemical type: Peptide from protein
Sequence: YIFINILLL
Position: 137-145
Source molecule (GenBank): YP_514469.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: toxin secretion ABC transporter ATP-binding peptide 23
Chemical type: Peptide from protein
Sequence: CIVLVIFVPM
Position: 56-65
Source molecule (GenBank): YP_514469.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: toxin secretion ABC transporter ATP-binding peptide 3
Chemical type: Peptide from protein
Sequence: VVLRQHVYI
Position: 125-133
Source molecule (GenBank): YP_514469.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: toxin secretion ABC transporter ATP-binding peptide 4
Chemical type: Peptide from protein
Sequence: VVLRQHVYIGL
Position: 125-135
Source molecule (GenBank): YP_514469.1
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: toxin secretion ABC transporter ATP-binding peptide 5
Chemical type: Peptide from protein
Sequence: RQHVYIGL
Position: 128-135
Source molecule (GenBank): YP_514469.1
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: toxin secretion ABC transporter ATP-binding peptide 6
Chemical type: Peptide from protein
Sequence: RQHVYIGLTYI
Position: 128-138
Source molecule (GenBank): YP_514469.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: toxin secretion ABC transporter ATP-binding peptide 7
Chemical type: Peptide from protein
Sequence: QHVYIGLTYI
Position: 129-138
Source molecule (GenBank): YP_514469.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: toxin secretion ABC transporter ATP-binding peptide 8
Chemical type: Peptide from protein
Sequence: HVYIGLTYIFI
Position: 130-140
Source molecule (GenBank): YP_514469.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: toxin secretion ABC transporter ATP-binding peptide 9
Chemical type: Peptide from protein
Sequence: VYIGLTYI
Position: 131-138
Source molecule (GenBank): YP_514469.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transaldolase peptide 1
Chemical type: Peptide from protein
Sequence: MGASFRNV
Position: 227-234
Source molecule (GenBank): YP_513796.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: transcription regulator peptide 1
Chemical type: Peptide from protein
Sequence: AQPISISIPL
Position: 38-47
Source molecule (GenBank): YP_513812.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: transcription termination factor Rho peptide 1
Chemical type: Peptide from protein
Sequence: SYFASPDDIYV
Position: 70-80
Source molecule (GenBank): YP_001892082.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: transcription termination factor Rho peptide 2
Chemical type: Peptide from protein
Sequence: VTLTNQDI
Position: 448-455
Source molecule (GenBank): YP_513369.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transcription-repair coupling factor,ATP-dependent peptide 1
Chemical type: Peptide from protein
Sequence: LPPSTNIHL
Position: 274-282
Source molecule (GenBank): YP_513630.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transglutaminase-like superfamily domain protein peptide 1
Chemical type: Peptide from protein
Sequence: GTGSGNHVT
Position: 651-659
Source molecule (GenBank): YP_512852.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: translation initiation factor IF-2 peptide 1
Chemical type: Peptide from protein
Sequence: VIYEGTLESL
Position: 793-802
Source molecule (GenBank): YP_514434.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transporter AcrB/AcrD/AcrF family peptide 1
Chemical type: Peptide from protein
Sequence: IVVYAPIGMM
Position: 442-451
Source molecule (GenBank): YP_514307.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transposase peptide 1
Chemical type: Peptide from protein
Sequence: AYIGMIKL
Position: 182-189
Source molecule (GenBank): YP_512883.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transposase peptide 11
Chemical type: Peptide from protein
Sequence: YYGKYRSI
Position: 5-12
Source molecule (GenBank): YP_513972.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transposase peptide 12
Chemical type: Peptide from protein
Sequence: TFYDCLNIL
Position: 96-104
Source molecule (GenBank): YP_513987.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transposase peptide 13
Chemical type: Peptide from protein
Sequence: KYKQRKEHERL
Position: 114-124
Source molecule (GenBank): YP_514012.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transposase peptide 14
Chemical type: Peptide from protein
Sequence: KSVQNPDLQEV
Position: 30-40
Source molecule (GenBank): YP_514165.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transposase peptide 15
Chemical type: Peptide from protein
Sequence: SAYIGMIKL
Position: 181-189
Source molecule (GenBank): YP_514228.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transposase peptide 16
Chemical type: Peptide from protein
Sequence: LSILRGWSL
Position: 150-158
Source molecule (GenBank): YP_514269.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transposase peptide 17
Chemical type: Peptide from protein
Sequence: ASFHKSSKL
Position: 226-234
Source molecule (GenBank): YP_514282.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transposase peptide 2
Chemical type: Peptide from protein
Sequence: DHPDASTL
Position: 75-82
Source molecule (GenBank): YP_513058.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transposase peptide 3
Chemical type: Peptide from protein
Sequence: ILYLPPYSPDL
Position: 245-255
Source molecule (GenBank): YP_513060.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transposase peptide 4
Chemical type: Peptide from protein
Sequence: KYEEGMTEF
Position: 15-23
Source molecule (GenBank): YP_513060.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transposase peptide 5
Chemical type: Peptide from protein
Sequence: KSVQNPDL
Position: 30-37
Source molecule (GenBank): YP_513094.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transposase peptide 6
Chemical type: Peptide from protein
Sequence: FSRLFKSV
Position: 25-32
Source molecule (GenBank): YP_513173.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transposase peptide 7
Chemical type: Peptide from protein
Sequence: AYHSNEIRQHI
Position: 117-127
Source molecule (GenBank): YP_513240.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transposase peptide 8
Chemical type: Peptide from protein
Sequence: YSGYTNTEIF
Position: 194-203
Source molecule (GenBank): YP_513367.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Transposase peptide 9
Chemical type: Peptide from protein
Sequence: LAYQTQRRSIV
Position: 168-178
Source molecule (GenBank): YP_513430.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Trehalase, pseuodgene peptide 1
Chemical type: Peptide from protein
Sequence: QYIKQMWSF
Position: 93-101
Source molecule (GenBank): YP_513837.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: tRNA modification GTPase trmE peptide 1
Chemical type: Peptide from protein
Sequence: IYLRMYVEASI
Position: 162-172
Source molecule (GenBank): YP_513860.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: tRNA modification GTPase trmE peptide 2
Chemical type: Peptide from protein
Sequence: VGYTNQNESI
Position: 373-382
Source molecule (GenBank): YP_513860.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: tRNA processing ribonuclease BN peptide 1
Chemical type: Peptide from protein
Sequence: ESLQNFLFENM
Position: 64-74
Source molecule (GenBank): YP_514542.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: tRNA processing ribonuclease BN peptide 3
Chemical type: Peptide from protein
Sequence: MQYMKVTL
Position: 267-274
Source molecule (GenBank): YP_514542.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: tryptophan synthase alpha chain peptide 1
Chemical type: Peptide from protein
Sequence: STLKQISKL
Position: 162-170
Source molecule (GenBank): YP_512897.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: tryptophan synthase beta chain peptide 1
Chemical type: Peptide from protein
Sequence: GRGDKDIFT
Position: 377-385
Source molecule (GenBank): YP_512898.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: twitching motility protein PilT peptide 1
Chemical type: Peptide from protein
Sequence: AVFRRLENTI
Position: 95-104
Source molecule (GenBank): YP_514398.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Type III restriction enzyme peptide 1
Chemical type: Peptide from protein
Sequence: KSYNPDFAYL
Position: 876-885
Source molecule (GenBank): YP_513297.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Type IV pili fiber building block protein peptide 1
Chemical type: Peptide from protein
Sequence: AMDSLQSSL
Position: 315-323
Source molecule (GenBank): YP_513163.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Type IV pili glycosylation protein peptide 1
Chemical type: Peptide from protein
Sequence: AEYIIILPLL
Position: 227-236
Source molecule (GenBank): YP_513197.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Type IV pili glycosylation protein peptide 2
Chemical type: Peptide from protein
Sequence: MPFMHYTVLNL
Position: 1-11
Source molecule (GenBank): YP_513197.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: UDP-N-acetylmuramate--alanine ligase peptide 1
Chemical type: Peptide from protein
Sequence: YNVQNATACI
Position: 277-286
Source molecule (GenBank): YP_512967.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: UDP-N-acetylmuramate--alanine ligase peptide 2
Chemical type: Peptide from protein
Sequence: VIITNIDLDHM
Position: 174-184
Source molecule (GenBank): YP_512967.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase peptide 1
Chemical type: Peptide from protein
Sequence: LSQNNFQIESL
Position: 16-26
Source molecule (GenBank): YP_513262.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase peptide 2
Chemical type: Peptide from protein
Sequence: LNSYNPNNL
Position: 356-364
Source molecule (GenBank): YP_513262.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: UTP--glucose-1-phosphate uridylyltransferase peptide 1
Chemical type: Peptide from protein
Sequence: FFVRQPEAL
Position: 100-108
Source molecule (GenBank): YP_514018.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VacJ lipoprotein peptide 1
Chemical type: Peptide from protein
Sequence: VNYSVYGL
Position: 193-200
Source molecule (GenBank): YP_513510.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VacJ lipoprotein peptide 2
Chemical type: Peptide from protein
Sequence: AALRNAYI
Position: 225-232
Source molecule (GenBank): YP_513510.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Valyl-tRNA synthetase peptide 1
Chemical type: Peptide from protein
Sequence: KAHLNDAKDTI
Position: 739-749
Source molecule (GenBank): YP_513005.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 1
Chemical type: Peptide from protein
Sequence: FIITILYFI
Position: 80-88
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 10
Chemical type: Peptide from protein
Sequence: ILYFIALFLL
Position: 84-93
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 11
Chemical type: Peptide from protein
Sequence: ILYFIALFLLI
Position: 84-94
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 12
Chemical type: Peptide from protein
Sequence: LYFIALFLL
Position: 85-93
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 13
Chemical type: Peptide from protein
Sequence: IALFLLII
Position: 88-95
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 14
Chemical type: Peptide from protein
Sequence: IALFLLIITFL
Position: 88-98
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 15
Chemical type: Peptide from protein
Sequence: ALFLLIITFL
Position: 89-98
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 17
Chemical type: Peptide from protein
Sequence: LIITFLAI
Position: 93-100
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 18
Chemical type: Peptide from protein
Sequence: LYAQNKTTI
Position: 371-379
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 19
Chemical type: Peptide from protein
Sequence: YVLFNGVMGVI
Position: 134-144
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 2
Chemical type: Peptide from protein
Sequence: FIITILYFIAL
Position: 80-90
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 20
Chemical type: Peptide from protein
Sequence: SGDKYAFV
Position: 403-410
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 21
Chemical type: Peptide from protein
Sequence: TYLAMLGYLM
Position: 347-356
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 3
Chemical type: Peptide from protein
Sequence: IITILYFIAL
Position: 81-90
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 4
Chemical type: Peptide from protein
Sequence: ITILYFIAL
Position: 82-90
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 5
Chemical type: Peptide from protein
Sequence: ITILYFIALFL
Position: 82-92
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 7
Chemical type: Peptide from protein
Sequence: TILYFIALFL
Position: 83-92
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 8
Chemical type: Peptide from protein
Sequence: TILYFIALFLL
Position: 83-93
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: virulence factor MviN peptide 9
Chemical type: Peptide from protein
Sequence: ILYFIALFL
Position: 84-92
Source molecule (GenBank): YP_513976.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: YggT family protein peptide 1
Chemical type: Peptide from protein
Sequence: FAVINMYVYL
Position: 108-117
Source molecule (GenBank): YP_514530.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: yieG peptide 1
Chemical type: Peptide from protein
Sequence: IIFCVIMFL
Position: 423-431
Source molecule (GenBank): YP_513111.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo