Reference: Tongqing Zhou; Jiang Zhu; Xueling Wu; Stephanie Moquin; Baoshan Zhang; Priyamvada Acharya; Ivelin S Georgiev; Han R Altae-Tran; Gwo-Yu Chuang; M Gordon Joyce; Young Do Kwon; Nancy S Longo; Mark K Louder; Timothy Luongo; Krisha McKee; Chaim A Schramm; Jeff Skinner; Yongping Yang; Zhongjia Yang; Zhenhai Zhang; Anqi Zheng; Mattia Bonsignori; Barton F Haynes; Johannes F Scheid; Michel C Nussenzweig; Melissa Simek; Dennis R Burton; Wayne C Koff; James C Mullikin; Mark Connors; Lawrence Shapiro; Gary J Nabel; John R Mascola; Peter D Kwong. "Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies." Immunity (2013).

Epitope: Epitope of VRC-CH31 Fab on HIV-1 gp120 93TH057
Chemical type: Discontinuous protein residues
Discontinuous residues: N278, T280, N281, N282, A283, K284, N355, S365, G366, G367, D368, I371, T449, R450, D451, G452, G453, A454, N455, N456
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.15

Epitope: Epitope of VRC-CH31 Fab on HIV-1 gp120 93TH057
Chemical type: Discontinuous protein residues
Discontinuous residues: N278, T280, N281, N282, A283, K284, N355, S365, G366, G367, D368, I371, T449, R450, D451, G452, G453, A454, N455, N456
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 37.8

Epitope: Epitope of VRC-CH31 Fab on HIV-1 gp120 93TH057(3415V1)
Chemical type: Discontinuous protein residues
Discontinuous residues: N278, T280, N282, A283, N355, K357, S365, G366, G367, D368, I371, Q426, T449, R450, D451, G452, G453, N455, E460, G467
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.25

Epitope: Epitope of VRC-CH31 Fab on HIV-1 gp120 93TH057(3415V1)
Chemical type: Discontinuous protein residues
Discontinuous residues: N278, T280, N282, A283, N355, K357, S365, G366, G367, D368, I371, Q426, T449, R450, D451, G452, G453, N455, E460, G467
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 37.8

Epitope: Epitope of VRC-CH31 Fab on HIV-1 gp120 93TH057(KER2018_11)
Chemical type: Discontinuous protein residues
Discontinuous residues: N278, N282, A283, N355, K357, S365, G366, G367, D368, I371, Q426, T449, R450, D451, G452, G453, E460, G467
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.28

Epitope: Epitope of VRC-CH31 Fab on HIV-1 gp120 93TH057(KER2018_11)
Chemical type: Discontinuous protein residues
Discontinuous residues: N278, N282, A283, N355, K357, S365, G366, G367, D368, I371, Q426, T449, R450, D451, G452, G453, E460, G467
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 37.8

Epitope: Epitope of VRC01 Fab on HIV-1 gp120 KER0218_11
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, L121, N272, S274, D275, N276, A277, K278, S358, G359, G360, D361, I364, V421, G422, Q423, T446, R447, D448, G449, G450, N451, T452, N459, E460, T461, R463, R470
Source molecule (GenBank): Q3ZLH8.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.59
Host: M 56 years

Epitope: Epitope of VRC01 Fab on HIV-1 gp120 KER0218_11
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, L121, N272, S274, D275, N276, A277, K278, S358, G359, G360, D361, I364, V421, G422, Q423, T446, R447, D448, G449, G450, N451, T452, N459, E460, T461, R463, R470
Source molecule (GenBank): Q3ZLH8.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.15
Host: M 56 years

Epitope: Epitope of VRC01 Fab on HIV-1 gp120 ZM176.66
Chemical type: Discontinuous protein residues
Discontinuous residues: G81, N160, T162, D163, N164, A165, K166, K224, S232, G233, G234, D235, I238, V293, G294, R295, T318, R319, D320, G321, G322, N323, D324, D327, T328, E329, T330, R332, R339
Source molecule (GenBank): 4LST_G
Assay category: BCell
Result: Positive
Quantitative measurement: 2.55
Host: M 56 years

Epitope: Epitope of VRC01 Fab on HIV-1 gp120 ZM176.66
Chemical type: Discontinuous protein residues
Discontinuous residues: G81, N160, T162, D163, N164, A165, K166, K224, S232, G233, G234, D235, I238, V293, G294, R295, T318, R319, D320, G321, G322, N323, D324, D327, T328, E329, T330, R332, R339
Source molecule (GenBank): 4LST_G
Assay category: BCell
Result: Positive
Quantitative measurement: 4.15
Host: M 56 years

Epitope: Epitope of 3BNC117 Fab on HIV-1 gp120 C1086
Chemical type: Discontinuous protein residues
Discontinuous residues: N265, T267, N268, N269, A270, K271, K344, E349, S352, G353, G354, D355, I358, V414, L439, R440, D441, G442, G443, Q444, T453, R455, G457
Source molecule (GenBank): ACS67966.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.0
Host: M

Epitope: Epitope of 3BNC117 Fab on HIV-1 gp120 C1086
Chemical type: Discontinuous protein residues
Discontinuous residues: N265, T267, N268, N269, A270, K271, K344, E349, S352, G353, G354, D355, I358, V414, L439, R440, D441, G442, G443, Q444, T453, R455, G457
Source molecule (GenBank): ACS67966.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.81
Host: M

Epitope: Epitope of VRC-PG20 Fab on HIV-1 gp120 93TH057
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, L121, T122, T259, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, T424, G425, Q426, T449, R450, D451, G452, G453, A454, N455, N459, E460, T461, R463, G465, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.3

Epitope: Epitope of VRC-PG20 Fab on HIV-1 gp120 93TH057
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, L121, T122, T259, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, T424, G425, Q426, T449, R450, D451, G452, G453, A454, N455, N459, E460, T461, R463, G465, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC-PG20 Fab on HIV-1 gp120 93TH057
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, L121, T122, T259, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, T424, G425, Q426, T449, R450, D451, G452, G453, A454, N455, N459, E460, T461, R463, G465, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC-PG20 Fab on HIV-1 gp120 93TH057
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, L121, T122, T259, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, T424, G425, Q426, T449, R450, D451, G452, G453, A454, N455, N459, E460, T461, R463, G465, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 29.3

Epitope: Epitope of VRC-PG20 Fab on HIV-1 gp120 93TH057
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, L121, T122, T259, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, T424, G425, Q426, T449, R450, D451, G452, G453, A454, N455, N459, E460, T461, R463, G465, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC-PG20 Fab on HIV-1 gp120 93TH057
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, L121, T122, T259, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, T424, G425, Q426, T449, R450, D451, G452, G453, A454, N455, N459, E460, T461, R463, G465, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC-PG20 Fab on HIV-1 gp120 93TH057
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, L121, T122, T259, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, T424, G425, Q426, T449, R450, D451, G452, G453, A454, N455, N459, E460, T461, R463, G465, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VRC-PG20 Fab on HIV-1 gp120 93TH057
Chemical type: Discontinuous protein residues
Discontinuous residues: K96, L121, T122, T259, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, T424, G425, Q426, T449, R450, D451, G452, G453, A454, N455, N459, E460, T461, R463, G465, N468
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive