LiteFold/IEDB huggingface dataset:
Reference: Toshio Naito; Hitoshi Ogasawara; Hiroshi Kaneko; Takashi Hishikawa; Iwao Sekigawa; Hiroshi Hashimoto; Naoki Maruyama. "Immune abnormalities induced by human endogenous retroviral peptides: with reference to the pathogenesis of systemic lupus erythematosus." Journal of clinical immunology (2003).

Epitope: CKS-17
Chemical type: Peptide from protein
Sequence: LQNRRGLDLLFLKEGGL
Position: 0-16
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 4-1
Chemical type: Peptide from protein
Sequence: YQNRLALDYLLAAEGGV
Position: 541-557
Source molecule (GenBank): AAP06678.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: E V Staikou; J G Routsias; A A Makri; A Terzoglou; M Sakarellos-Daitsiotis; C Sakarellos; G Panayotou; H M Moutsopoulos; A G Tzioufas. "Calreticulin binds preferentially with B cell linear epitopes of Ro60 kD autoantigen, enhancing recognition by anti-Ro60 kD autoantibodies." Clinical and experimental immunology (2003).

Epitope: Ro 175–184 (p10)
Chemical type: Peptide from protein
Sequence: NGWSHKDLLR
Position: 175-184
Source molecule (GenBank): AAA35493.1
Assay category: BCell
Result: Positive

Epitope: Ro 175–184 (p10)
Chemical type: Peptide from protein
Sequence: NGWSHKDLLR
Position: 175-184
Source molecule (GenBank): AAA35493.1
Assay category: BCell
Result: Positive-Low

Epitope: Ro 216–232 (p17)
Chemical type: Peptide from protein
Sequence: KALSVETEKLLKYLEAV
Position: 216-232
Source molecule (GenBank): AAA35493.1
Assay category: BCell
Result: Positive-Low

Epitope: Ro 216–232 (p17)
Chemical type: Peptide from protein
Sequence: KALSVETEKLLKYLEAV
Position: 216-232
Source molecule (GenBank): AAA35493.1
Assay category: BCell
Result: Positive
Reference: Sudha Visvanathan; Jamie K Scott; Kwan-Ki Hwang; Michelle Banares; Jennifer M Grossman; Joan T Merrill; John FitzGerald; Reginald U Chukwuocha; Betty P Tsao; Bevra H Hahn; Pojen P Chen. "Identification and characterization of a peptide mimetic that may detect a species of disease-associated anticardiolipin antibodies in patients with the antiphospholipid syndrome." Arthritis and rheumatism (2003).

Epitope: CL151
Chemical type: Peptide, no natural source
Sequence: APVCVWERLSPYRERCV
Assay category: BCell
Result: Positive
Host: M 19 years

Epitope: CL151A
Chemical type: Peptide, no natural source
Sequence: APVCVWERLSPYRERCV
Assay category: BCell
Result: Positive
Host: M 19 years

Epitope: CL154A
Chemical type: Peptide, no natural source
Sequence: HWDPFSLSAYFP
Assay category: BCell
Result: Positive
Host: M 19 years

Epitope: CL154A
Chemical type: Peptide, no natural source
Sequence: HWDPFSLSAYFP
Assay category: BCell
Result: Negative
Host: M 19 years

Epitope: CL154E
Chemical type: Peptide, no natural source
Sequence: HWDPFSLSAYFPGGGS
Assay category: BCell
Result: Positive
Host: M 19 years

Epitope: CL154E
Chemical type: Peptide, no natural source
Sequence: HWDPFSLSAYFPGGGS
Assay category: BCell
Result: Negative
Host: M 19 years

Epitope: CL154C
Chemical type: Peptide, no natural source
Sequence: CHWDPFSLSAYFPGGGSC
Assay category: BCell
Result: Negative

Epitope: CL154C
Chemical type: Peptide, no natural source
Sequence: CHWDPFSLSAYFPGGGSC
Assay category: BCell
Result: Positive

Epitope: CL154C
Chemical type: Peptide, no natural source
Sequence: CHWDPFSLSAYFPGGGSC
Assay category: BCell
Result: Positive
Host: M 19 years

Epitope: CL154C
Chemical type: Peptide, no natural source
Sequence: CHWDPFSLSAYFPGGGSC
Assay category: BCell
Result: Positive

Epitope: CL154C
Chemical type: Peptide, no natural source
Sequence: CHWDPFSLSAYFPGGGSC
Assay category: BCell
Result: Positive

Epitope: Cardiolipin
Chemical type: Lipid
Assay category: BCell
Result: Positive

Epitope: Cardiolipin
Chemical type: Lipid
Assay category: BCell
Result: Negative
Reference: John G Routsias; Evgenia Touloupi; Eleni Dotsika; Avrilia Moulia; Vassilios Tsikaris; Constantinos Sakarellos; Maria Sakarellos-Daitsiotis; Haralampos M Moutsopoulos; Athanasios G Tzioufas. "Unmasking the anti-La/SSB response in sera from patients with Sjogren's syndrome by specific blocking of anti-idiotypic antibodies to La/SSB antigenic determinants." Molecular medicine (Cambridge, Mass.) (2002).

Epitope: pep289-308
Chemical type: Peptide from protein
Sequence: NNGNLQLRNKEVTWEVLEG
Position: 290-308
Source molecule (GenBank): P05455.2
Assay category: BCell
Result: Positive

Epitope: pep289-308
Chemical type: Peptide from protein
Sequence: NNGNLQLRNKEVTWEVLEG
Position: 290-308
Source molecule (GenBank): P05455.2
Assay category: BCell
Result: Positive

Epitope: pep289-308
Chemical type: Peptide from protein
Sequence: NNGNLQLRNKEVTWEVLEG
Position: 290-308
Source molecule (GenBank): P05455.2
Assay category: BCell
Result: Positive

Epitope: cpep289-308
Chemical type: Peptide, no natural source
Sequence: FEYFPSHFFVPELEVTIIC
Assay category: BCell
Result: Positive

Epitope: cpep289-308
Chemical type: Peptide, no natural source
Sequence: FEYFPSHFFVPELEVTIIC
Assay category: BCell
Result: Positive

Epitope: pep349-364
Chemical type: Peptide from protein
Sequence: SGKGKVQFQGKKTKF
Position: 350-364
Source molecule (GenBank): P05455.2
Assay category: BCell
Result: Positive

Epitope: pep349-364
Chemical type: Peptide from protein
Sequence: SGKGKVQFQGKKTKF
Position: 350-364
Source molecule (GenBank): P05455.2
Assay category: BCell
Result: Positive

Epitope: pep349-364
Chemical type: Peptide from protein
Sequence: SGKGKVQFQGKKTKF
Position: 350-364
Source molecule (GenBank): P05455.2
Assay category: BCell
Result: Positive

Epitope: cpep349-364
Chemical type: Peptide, no natural source
Sequence: FRFLALKLYFSFTRP
Assay category: BCell
Result: Positive

Epitope: cpep349-364
Chemical type: Peptide, no natural source
Sequence: FRFLALKLYFSFTRP
Assay category: BCell
Result: Positive
Reference: Guo-Chang Fan; Ram Raj Singh. "Vaccination with minigenes encoding V(H)-derived major histocompatibility complex class I-binding epitopes activates cytotoxic T cells that ablate autoantibody-producing B cells and inhibit lupus." The Journal of experimental medicine (2002).

Epitope: VH1
Chemical type: Peptide from protein
Sequence: VKQSHGKSL
Position: 37-45
Source molecule (GenBank): AAA62638.1
Assay category: BCell
Result: Positive
Host:  3 months

Epitope: VH1
Chemical type: Peptide from protein
Sequence: VKQSHGKSL
Position: 37-45
Source molecule (GenBank): AAA62638.1
Assay category: TCell
Result: Positive
Host:  3 months
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VH1
Chemical type: Peptide from protein
Sequence: VKQSHGKSL
Position: 37-45
Source molecule (GenBank): AAA62638.1
Assay category: TCell
Result: Positive
Host:  3 months
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VH1
Chemical type: Peptide from protein
Sequence: VKQSHGKSL
Position: 37-45
Source molecule (GenBank): AAA62638.1
Assay category: MhcBinding
Result: Positive

Epitope: VH2
Chemical type: Peptide from protein
Sequence: KFKGKATL
Position: 63-70
Source molecule (GenBank): AAA62638.1
Assay category: BCell
Result: Positive
Host:  3 months

Epitope: VH2
Chemical type: Peptide from protein
Sequence: KFKGKATL
Position: 63-70
Source molecule (GenBank): AAA62638.1
Assay category: MhcBinding
Result: Positive

Chemical type: Peptide from protein
Sequence: SSSTAHMEL
Position: 75-83
Source molecule (GenBank): AAA62638.1
Assay category: MhcBinding
Result: Positive

Chemical type: Peptide from protein
Sequence: YYYGSSYGY
Position: 102-110
Source molecule (GenBank): AAA62638.1
Assay category: MhcBinding
Result: Positive

Chemical type: Peptide from protein
Sequence: DYWGQGTS
Position: 113-120
Source molecule (GenBank): AAA62638.1
Assay category: MhcBinding
Result: Positive

Epitope: VH3
Chemical type: Peptide from protein
Sequence: YYCARDSP
Position: 94-101
Source molecule (GenBank): AAA62638.1
Assay category: BCell
Result: Positive
Host:  3 months
Reference: M T McClain; R H Scofield; B T Kurien; T F Gross; J A James. "Selective small antigenic structures are capable of inducing widespread autoimmunity which closely mimics the humoral fine specificity of human SLE." Scandinavian journal of immunology (2002).

Epitope: Ro peptide 274
Chemical type: Peptide from protein
Sequence: LQEMPTLALLRNLGKM
Assay category: BCell
Result: Positive

Epitope: Ro peptide 274
Chemical type: Peptide from protein
Sequence: LQEMPTLALLRNLGKM
Assay category: BCell
Result: Positive

Epitope: Ro peptide 274
Chemical type: Peptide from protein
Sequence: LQEMPTLALLRNLGKM
Assay category: BCell
Result: Positive

Epitope: Ro peptide 274
Chemical type: Peptide from protein
Sequence: LQEMPTLALLRNLGKM
Assay category: BCell
Result: Positive

Epitope: Ro peptide 274
Chemical type: Peptide from protein
Sequence: LQEMPTLALLRNLGKM
Assay category: BCell
Result: Positive

Epitope: Ro peptide 274
Chemical type: Peptide from protein
Sequence: LQEMPTLALLRNLGKM
Assay category: BCell
Result: Positive

Epitope: Ro peptide 274
Chemical type: Peptide from protein
Sequence: LQEMPTLALLRNLGKM
Assay category: BCell
Result: Positive
Reference: Kyung-Jong Lee; Xingwen Dong; Jingsong Wang; Yoshihiko Takeda; William S Dynan. "Identification of human autoantibodies to the DNA ligase IV/XRCC4 complex and mapping of an autoimmune epitope to a potential regulatory region." Journal of immunology (Baltimore, Md. : 1950) (2002).

Epitope: Peptide 1
Chemical type: Peptide from protein
Sequence: QEGETAICSEMTADRDPVYDESTDE
Position: 211-235
Source molecule (GenBank): AAH05259.1
Assay category: BCell
Result: Negative

Epitope: Peptide 1
Chemical type: Peptide from protein
Sequence: QEGETAICSEMTADRDPVYDESTDE
Position: 211-235
Source molecule (GenBank): AAH05259.1
Assay category: BCell
Result: Negative

Epitope: Peptide 2
Chemical type: Peptide from protein
Sequence: MTADRDPVYDESTDEESENQTDLSG
Position: 221-245
Source molecule (GenBank): AAH05259.1
Assay category: BCell
Result: Negative

Epitope: Peptide 2
Chemical type: Peptide from protein
Sequence: MTADRDPVYDESTDEESENQTDLSG
Position: 221-245
Source molecule (GenBank): AAH05259.1
Assay category: BCell
Result: Negative

Epitope: Peptide 4
Chemical type: Peptide from protein
Sequence: VSKDDSIISSLDVTD
Position: 251-265
Source molecule (GenBank): AAH05259.1
Assay category: BCell
Result: Positive

Epitope: Peptide 4
Chemical type: Peptide from protein
Sequence: VSKDDSIISSLDVTD
Position: 251-265
Source molecule (GenBank): AAH05259.1
Assay category: BCell
Result: Negative

Epitope: Peptide 4
Chemical type: Peptide from protein
Sequence: VSKDDSIISSLDVTD
Position: 251-265
Source molecule (GenBank): AAH05259.1
Assay category: BCell
Result: Positive
Reference: G Riemekasten; C Weiss; S Schneider; A Thiel; A Bruns; F Schumann; S Bläss; G-R Burmester; F Hiepe. "T cell reactivity against the SmD1(83-119) C terminal peptide in patients with systemic lupus erythematosus." Annals of the rheumatic diseases (2002).

Epitope: SmD1<sub>83-119</sub>
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): P62314.1
Assay category: BCell
Result: Positive

Epitope: SmD1<sub>83-119</sub>
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): P62314.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: SmD1<sub>83-119</sub>
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): P62314.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: SmD1<sub>83-119</sub>
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): P62314.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: SmD1<sub>83-119</sub>
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): P62314.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: S Mihara; N Suzuki; Y Takeba; K Soejima; S Yamamoto. "Combination of molecular mimicry and aberrant autoantigen expression is important for development of anti-Fas ligand autoantibodies in patients with systemic lupus erythematosus." Clinical and experimental immunology (2002).

Epitope: FasL 161-170
Chemical type: Peptide from protein
Sequence: EWEDTYGIVL
Position: 161-170
Source molecule (GenBank): NP_000630.1
Assay category: BCell
Result: Positive
Host: F 14 to 45

Epitope: FasL 161-170
Chemical type: Peptide from protein
Sequence: EWEDTYGIVL
Position: 161-170
Source molecule (GenBank): NP_000630.1
Assay category: BCell
Result: Positive
Host: F 14 to 45

Epitope: FasL (171-180)
Chemical type: Peptide from protein
Sequence: LSGVKYKKGG
Position: 171-180
Source molecule (GenBank): NP_000630.1
Assay category: BCell
Result: Negative
Host: F 14 to 45

Epitope: FasL (165-174)
Chemical type: Peptide from protein
Sequence: TYGIVLLSGV
Position: 165-174
Source molecule (GenBank): NP_000630.1
Assay category: BCell
Result: Positive
Host: F 14 to 45

Epitope: FasL (165-174)
Chemical type: Peptide from protein
Sequence: TYGIVLLSGV
Position: 165-174
Source molecule (GenBank): NP_000630.1
Assay category: BCell
Result: Positive-Low
Host: F 14 to 45

Epitope: EBV (335-344)
Chemical type: Peptide from protein
Sequence: LWDQTYGVPD
Position: 335-344
Source molecule (GenBank): P03189.1
Assay category: BCell
Result: Positive-Low
Host: F 14 to 45

Epitope: SA transl (297-306)
Chemical type: Peptide from protein
Sequence: EWESTYSILG
Position: 297-306
Source molecule (GenBank): AAC45625.1
Assay category: BCell
Result: Positive
Host: F 14 to 45
Reference: Micah T McClain; Paul A Ramsland; Kenneth M Kaufman; Judith A James. "Anti-sm autoantibodies in systemic lupus target highly basic surface structures of complexed spliceosomal autoantigens." Journal of immunology (Baltimore, Md. : 1950) (2002).

Epitope: Sm D2 epitope 1
Chemical type: Peptide from protein
Sequence: MSLLNKPKSEMTP
Position: 1-13
Source molecule (GenBank): NP_004588.1
Assay category: BCell
Result: Negative
Host: F 18-30 years

Epitope: Sm D2 epitope 1
Chemical type: Peptide from protein
Sequence: MSLLNKPKSEMTP
Position: 1-13
Source molecule (GenBank): NP_004588.1
Assay category: BCell
Result: Positive
Host: F 18-30 years

Epitope: Sm D2 epitope 2
Chemical type: Peptide from protein
Sequence: SVLTQSVKNNTQ
Position: 30-41
Source molecule (GenBank): NP_004588.1
Assay category: BCell
Result: Negative
Host: F 18-30 years

Epitope: Sm D2 epitope 2
Chemical type: Peptide from protein
Sequence: SVLTQSVKNNTQ
Position: 30-41
Source molecule (GenBank): NP_004588.1
Assay category: BCell
Result: Positive
Host: F 18-30 years

Epitope: Sm D2 epitope 3
Chemical type: Peptide from protein
Sequence: WTEVPKSGKGK
Position: 74-84
Source molecule (GenBank): NP_004588.1
Assay category: BCell
Result: Negative
Host: F 18-30 years

Epitope: Sm D2 epitope 3
Chemical type: Peptide from protein
Sequence: WTEVPKSGKGK
Position: 74-84
Source molecule (GenBank): NP_004588.1
Assay category: BCell
Result: Positive
Host: F 18-30 years

Epitope: Sm D2 epitope 4
Chemical type: Peptide from protein
Sequence: GKKKSKPVNKDRYISKMFLRGDS
Position: 83-105
Source molecule (GenBank): NP_004588.1
Assay category: BCell
Result: Negative
Host: F 18-30 years

Epitope: Sm D2 epitope 4
Chemical type: Peptide from protein
Sequence: GKKKSKPVNKDRYISKMFLRGDS
Position: 83-105
Source molecule (GenBank): NP_004588.1
Assay category: BCell
Result: Positive-High
Host: F 18-30 years

Epitope: Sm D3 epitope 2
Chemical type: Peptide from protein
Sequence: QVYIRGSKI
Position: 60-68
Source molecule (GenBank): NP_004166.1
Assay category: BCell
Result: Positive
Host: F 18-30 years

Epitope: Sm D3 epitope 2
Chemical type: Peptide from protein
Sequence: QVYIRGSKI
Position: 60-68
Source molecule (GenBank): NP_004166.1
Assay category: BCell
Result: Negative
Host: F 18-30 years

Epitope: Sm D3 epitope 3
Chemical type: Peptide from protein
Sequence: MLKNAPMLKSMKNKNQGSGAGRGKAAILKAQ
Position: 76-106
Source molecule (GenBank): NP_004166.1
Assay category: BCell
Result: Negative
Host: F 18-30 years

Epitope: Sm D3 epitope 3
Chemical type: Peptide from protein
Sequence: MLKNAPMLKSMKNKNQGSGAGRGKAAILKAQ
Position: 76-106
Source molecule (GenBank): NP_004166.1
Assay category: BCell
Result: Positive-High
Host: F 18-30 years
Reference: H P Jaekel; T Klopsch; B Benkenstein; N Grobe; A Baldauf; W Schoessler; E Werle. "Reactivities to the Sm autoantigenic complex and the synthetic SmD1-aa83-119 peptide in systemic lupus erythematosus and other autoimmune diseases." Journal of autoimmunity (2001).

Epitope: SmD1-aa83-119
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): NP_008869.1
Assay category: BCell
Result: Positive

Epitope: SmD1-aa83-119
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): NP_008869.1
Assay category: BCell
Result: Positive

Epitope: SmD1-aa83-119
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): NP_008869.1
Assay category: BCell
Result: Negative

Epitope: SmD1-aa83-119
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): NP_008869.1
Assay category: BCell
Result: Positive

Epitope: SmD1-aa83-119
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): NP_008869.1
Assay category: BCell
Result: Positive-Low

Epitope: SmD1-aa83-119
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): NP_008869.1
Assay category: BCell
Result: Negative
Reference: G Riemekasten; A Kawald; C Weiss; A Meine; J Marell; R Klein; B Hocher; C Meisel; G Hausdorf; R Manz; T Kamradt; G R Burmester; F Hiepe. "Strong acceleration of murine lupus by injection of the SmD1(83-119) peptide." Arthritis and rheumatism (2001).

Epitope: SmD1<sup>83-119</sup>
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): NP_033252.1
Assay category: BCell
Result: Positive
Host: F 12-15 weeks

Epitope: SmD1<sup>83-119</sup>
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): NP_033252.1
Assay category: BCell
Result: Positive-Low
Host: F 12-15 weeks

Epitope: SmD1<sup>83-119</sup>
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): NP_033252.1
Assay category: BCell
Result: Positive
Host: F 12-15 weeks

Epitope: SmD1<sup>83-119</sup>
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): NP_033252.1
Assay category: TCell
Result: Positive-Low
Host: F 3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SmD1<sup>83-119</sup>
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): NP_033252.1
Assay category: TCell
Result: Positive-Low
Host: F 3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SmD1<sup>83-119</sup>
Chemical type: Peptide from protein
Sequence: VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Position: 83-119
Source molecule (GenBank): NP_033252.1
Assay category: TCell
Result: Positive
Host: F 3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo
Reference: A N Scofield; B T Kurien; T P Gordon; R H Scofield. "Can B cell epitopes of 60 kDa Ro distinguish systemic lupus erythematosus from Sjögren's syndrome?" Lupus (2001).

Epitope: Ro-Map-171
Chemical type: Peptide from protein
Sequence: YKQRNGWSHKDLLRLSHLKP
Position: 171-190
Source molecule (GenBank): AAA35493.1
Assay category: BCell
Result: Positive

Epitope: Ro-Map-171
Chemical type: Peptide from protein
Sequence: YKQRNGWSHKDLLRLSHLKP
Position: 171-190
Source molecule (GenBank): AAA35493.1
Assay category: BCell
Result: Positive

Epitope: Ro-Map-215
Chemical type: Peptide from protein
Sequence: EKALSVETEKLLKYLEAV
Position: 215-232
Source molecule (GenBank): AAA35493.1
Assay category: BCell
Result: Positive

Epitope: Ro-Map-215
Chemical type: Peptide from protein
Sequence: EKALSVETEKLLKYLEAV
Position: 215-232
Source molecule (GenBank): AAA35493.1
Assay category: BCell
Result: Positive
Reference: F Monneaux; H Dumortier; G Steiner; J P Briand; S Muller. "Murine models of systemic lupus erythematosus: B and T cell responses to spliceosomal ribonucleoproteins in MRL/Fas(lpr) and (NZB x NZW)F(1) lupus mice." International immunology (2001).

Epitope: snRNP 70K (131-151)
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIEY
Position: 131-151
Source molecule (GenBank): NP_033250.3
Assay category: BCell
Result: Positive
Host:  21 weeks, 27 weeks, or 36 weeks

Epitope: snRNP 70K (131-151)
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIEY
Position: 131-151
Source molecule (GenBank): NP_033250.3
Assay category: TCell
Result: Positive
Host:  10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: snRNP 70K (131-151)
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIEY
Position: 131-151
Source molecule (GenBank): NP_033250.3
Assay category: TCell
Result: Positive
Host:  10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: snRNP 70K (131-151)
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIEY
Position: 131-151
Source molecule (GenBank): NP_033250.3
Assay category: TCell
Result: Positive
Host:  10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: snRNP 70K (131-151)
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIEY
Position: 131-151
Source molecule (GenBank): NP_033250.3
Assay category: TCell
Result: Positive
Host:  10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: snRNP 70K (131-151)
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIEY
Position: 131-151
Source molecule (GenBank): NP_033250.3
Assay category: MhcBinding
Result: Positive

Epitope: snRNP 70K (131-151)
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIEY
Position: 131-151
Source molecule (GenBank): NP_033250.3
Assay category: MhcBinding
Result: Positive

Epitope: snRNP 70K (21-41)
Chemical type: Peptide from protein
Sequence: YLPPLEKLPHEKHHNQPYCGI
Position: 21-41
Source molecule (GenBank): NP_033250.3
Assay category: BCell
Result: Positive
Host:  21 weeks, 27 weeks, or 36 weeks

Epitope: SmD1 (1-20)
Chemical type: Peptide from protein
Sequence: MKLVRFLMKLSHETVTIELK
Position: 1-20
Source molecule (GenBank): NP_033252.1
Assay category: BCell
Result: Positive-High
Host:  21 weeks, 27 weeks, or 36 weeks

Epitope: SmD1 (97-119)
Chemical type: Peptide from protein
Sequence: GRGRGRGRGRGRGRGRGRGGPRR
Position: 97-119
Source molecule (GenBank): NP_033252.1
Assay category: BCell
Result: Positive
Host:  21 weeks, 27 weeks, or 36 weeks

Epitope: A2 (50-70)
Chemical type: Peptide from protein
Sequence: RGFGFVTFSSMAEVDAAMAAR
Position: 50-70
Source molecule (GenBank): NP_058086.2
Assay category: BCell
Result: Positive
Host:  21 weeks, 27 weeks, or 36 weeks
Reference: K Dixit; R Ali. "Antigen binding characteristics of antibodies induced against nitric oxide modified plasmid DNA." Biochimica et biophysica acta (2001).

Epitope: Cardiolipin
Chemical type: Lipid
Assay category: BCell
Result: Positive
Host: F

Epitope: Chrondroitin sulphate
Chemical type: Lipid
Assay category: BCell
Result: Positive
Host: F