Reference: L K Myers; K Terato; J M Seyer; J M Stuart; A H Kang. "Characterization of a tolerogenic T cell epitope of type II collagen and its relevance to collagen-induced arthritis." Journal of immunology (Baltimore, Md. : 1950) (1992).

Epitope: CII 245-270
Chemical type: Peptide from protein
Sequence: PTGPLGPKGQTGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive
Host:  neonate

Epitope: CII 245-270
Chemical type: Peptide from protein
Sequence: PTGPLGPKGQTGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII 260-270
Chemical type: Peptide from protein
Sequence: IAGFKGEQGPK
Position: 393-403
Source molecule (GenBank): NP_989757.1
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII 260-270
Chemical type: Peptide from protein
Sequence: IAGFKGEQGPK
Position: 393-403
Source molecule (GenBank): NP_989757.1
Assay category: TCell
Result: Positive
Host:  neonate

Epitope: Peptide 1
Chemical type: Peptide, no natural source
Sequence: PTGAPGPKGQTGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 3
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGNSGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 4
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGNTGELGIPFKGEQGPK
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 5
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGQTGELGAAGNKGEQGPK
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 6
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGQTGELGAPGNKGEQGPK
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 8
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGQTGELGIAGFKGDTGAK
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 9
Chemical type: Peptide, no natural source
Sequence: ATGPLGPKGQTGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive
Host:  neonate

Epitope: Peptide 10
Chemical type: Peptide, no natural source
Sequence: PSGPLGPKGQTGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive
Host:  neonate

Epitope: Peptide 12
Chemical type: Peptide, no natural source
Sequence: PTGALGPKGQTGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive
Host:  neonate

Epitope: Peptide 14
Chemical type: Peptide, no natural source
Sequence: PTGPLGAKGQTGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive
Host:  neonate

Epitope: Peptide 16
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGQSGELGIAGFKGEQGPK
Assay category: TCell
Result: Positive
Host:  neonate

Epitope: Peptide 17
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGQTGEPGIAGFKGEQGPK
Assay category: TCell
Result: Positive
Host:  neonate

Epitope: Peptide 18
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGQTGELGAAGFKGEQGPK
Assay category: TCell
Result: Negative
Host:  neonate

Epitope: Peptide 19
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGQTGELGIPGFKGEQGPK
Assay category: TCell
Result: Negative
Host:  neonate

Epitope: Peptide 21
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGQTGELGIAGFAGEQGPK
Assay category: TCell
Result: Negative
Host:  neonate

Epitope: Peptide 22
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGQTGELGIAGFKGDQGPK
Assay category: TCell
Result: Negative
Host:  neonate

Epitope: Peptide 23
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGQTGELGIAGFKGETGPK
Assay category: TCell
Result: Positive
Host:  neonate

Epitope: Peptide 24
Chemical type: Peptide, no natural source
Sequence: PTGPLGPKGQTGELGIAGFKGEQGAK
Assay category: TCell
Result: Positive
Host:  neonate

Epitope: Peptide 25
Chemical type: Peptide, no natural source
Sequence: PKGQTGELGAAGFKGEQGPK
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 26
Chemical type: Peptide, no natural source
Sequence: PKGNTGELGIPGFKGEQGPK
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 27
Chemical type: Peptide, no natural source
Sequence: PKGQTGELGIAGNKGEQGPK
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 28
Chemical type: Peptide, no natural source
Sequence: PKGQTGELGIAGFAGEQGPK
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 29
Chemical type: Peptide, no natural source
Sequence: PKGQAGEPGIAGFKGDQGPK
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo