Reference: M P Protti; A A Manfredi; C Straub; J F Howard; B M Conti-Tronconi. "Immunodominant regions for T helper-cell sensitization on the human nicotinic receptor alpha subunit in myasthenia gravis." Proceedings of the National Academy of Sciences of the United States of America (1990).

Epitope: hAChRα1-14
Chemical type: Peptide from protein
Sequence: SEHETRLVAKLFKD
Position: 21-34
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα19-34
Chemical type: Peptide from protein
Sequence: VRPVEDHRQVVEVTVG
Position: 39-54
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα32-51
Chemical type: Peptide from protein
Sequence: TVGLQLIQLINVDEVNQIVT
Position: 52-71
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα48-67
Chemical type: Peptide from protein
Sequence: QIVTTNVRLKQQWVDYNLKW
Position: 68-87
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα63-80
Chemical type: Peptide from protein
Sequence: YNLKWNPDDYGGVKKIHI
Position: 83-100
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα89-105
Chemical type: Peptide from protein
Sequence: DLVLYNNADGDFAIVK
Position: 134-149
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα101-120
Chemical type: Peptide from protein
Sequence: AIVKFTKVLLQYTGHITWTPP
Position: 146-166
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα118-137
Chemical type: Peptide from protein
Sequence: WTPPAIFKSYCEIIVTHFPF
Position: 163-182
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα135-154
Chemical type: Peptide from protein
Sequence: FPFDEQNCSMKLGTWTYDGS
Position: 180-199
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα151-168
Chemical type: Peptide from protein
Sequence: YDGSVVAINPESDQPDLS
Position: 196-213
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα166-185
Chemical type: Peptide from protein
Sequence: DLSNFMESGEWVIKESRGWK
Position: 211-230
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα181-195
Chemical type: Peptide from protein
Sequence: SRGWKHSVTYSCCPDTPY
Position: 226-243
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα191-207
Chemical type: Peptide from protein
Sequence: SCCPDTPYLDITYHFVM
Position: 236-252
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα203-218
Chemical type: Peptide from protein
Sequence: YHFVMQRLPLYFIVNV
Position: 248-263
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα214-234
Chemical type: Peptide from protein
Sequence: FIVNVIIPCLLFSFLTGLVFY
Position: 259-279
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα230-249
Chemical type: Peptide from protein
Sequence: GLVFYLPTDSGEKMTLSIS
Position: 275-293
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα246-264
Chemical type: Peptide from protein
Sequence: SISVLLSLTVFLLVIVELI
Position: 291-309
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα261-280
Chemical type: Peptide from protein
Sequence: IVELIPSTSSAVPLIGKYMLF
Position: 305-325
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα280-297
Chemical type: Peptide from protein
Sequence: FTMVFVIASIIITVIVINT
Position: 325-343
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα293-308
Chemical type: Peptide from protein
Sequence: VIVINTHHRSPSTHVM
Position: 338-353
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα304-322
Chemical type: Peptide from protein
Sequence: STHVMPNWVRKVFIDTIPN
Position: 349-367
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα320-337
Chemical type: Peptide from protein
Sequence: IPNIMFFSTMKRPSREKQ
Position: 365-382
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα329-347
Chemical type: Peptide from protein
Sequence: MKRPSREKQDKKIFTEDID
Position: 374-392
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα343-356
Chemical type: Peptide from protein
Sequence: TEDIDISDISGKPG
Position: 388-401
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα352-368
Chemical type: Peptide from protein
Sequence: SGKPGPPPMGFHSPLIK
Position: 397-413
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα364-380
Chemical type: Peptide from protein
Sequence: HSPLIKHPEVKSAIEGIK
Position: 408-425
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα376-393
Chemical type: Peptide from protein
Sequence: IEGIKYIAETMKSDQESN
Position: 421-438
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα387-405
Chemical type: Peptide from protein
Sequence: KSDQESNNAAAEWKYVAM
Position: 432-449
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα403-421
Chemical type: Peptide from protein
Sequence: AMVMDHILLGVFMLVCIIG
Position: 448-466
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα419-437
Chemical type: Peptide from protein
Sequence: IIGTLAVFAGRLIELNQQG
Position: 464-482
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone