Reference: D N Bourdette; Y K Chou; R H Whitham; J Buckner; H J Kwon; G T Nepom; A Buenafe; S A Cooper; M Allegretta; G A Hashim; H Offner; A A Vandenbark. "Immunity to T cell receptor peptides in multiple sclerosis. III. Preferential immunogenicity of complementarity-determining region 2 peptides from disease-associated T cell receptor BV genes." Journal of immunology (Baltimore, Md. : 1950) (1998).

Epitope: BV5S2 13-33
Chemical type: Peptide from protein
Sequence: KTRGQQVTLRCSPKSGHDTVS
Position: 32-52
Source molecule (GenBank): AAB63910.1
Assay category: TCell
Result: Negative
Host:  33-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: BV5S2 13-33
Chemical type: Peptide from protein
Sequence: KTRGQQVTLRCSPKSGHDTVS
Position: 32-52
Source molecule (GenBank): AAB63910.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 10.0

Epitope: BV5S2 13-33
Chemical type: Peptide from protein
Sequence: KTRGQQVTLRCSPKSGHDTVS
Position: 32-52
Source molecule (GenBank): AAB63910.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 10.0

Epitope: BV5S2 25-42
Chemical type: Peptide from protein
Sequence: PKSGHDTVSWYQQALGQG
Position: 44-61
Source molecule (GenBank): AAB63910.1
Assay category: TCell
Result: Positive
Host:  33-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: BV5S2 25-42
Chemical type: Peptide from protein
Sequence: PKSGHDTVSWYQQALGQG
Position: 44-61
Source molecule (GenBank): AAB63910.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 10.0

Epitope: BV5S2 25-42
Chemical type: Peptide from protein
Sequence: PKSGHDTVSWYQQALGQG
Position: 44-61
Source molecule (GenBank): AAB63910.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 200.0

Epitope: BV5S2 33-52
Chemical type: Peptide from protein
Sequence: SWYQQALGQGPQFIFQYYEE
Position: 52-71
Source molecule (GenBank): AAB63910.1
Assay category: TCell
Result: Positive
Host:  33-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: BV5S2 33-52
Chemical type: Peptide from protein
Sequence: SWYQQALGQGPQFIFQYYEE
Position: 52-71
Source molecule (GenBank): AAB63910.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 10000.0

Epitope: BV5S2 33-52
Chemical type: Peptide from protein
Sequence: SWYQQALGQGPQFIFQYYEE
Position: 52-71
Source molecule (GenBank): AAB63910.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 5000.0

Epitope: BV5S2 38-58
Chemical type: Peptide from protein
Sequence: ALGQGPQFIFQYYEEEERQRG
Position: 57-77
Source molecule (GenBank): AAB63910.1
Assay category: TCell
Result: Positive
Host:  33-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: BV5S2 38-58
Chemical type: Peptide from protein
Sequence: ALGQGPQFIFQYYEEEERQRG
Position: 57-77
Source molecule (GenBank): AAB63910.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 50.0

Epitope: BV5S2 38-58
Chemical type: Peptide from protein
Sequence: ALGQGPQFIFQYYEEEERQRG
Position: 57-77
Source molecule (GenBank): AAB63910.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 100.0

Epitope: BV5S2 48-67
Chemical type: Peptide from protein
Sequence: QYYEEEERQRGNFPDRFSG
Position: 67-85
Source molecule (GenBank): AAB63910.1
Assay category: TCell
Result: Negative
Host:  33-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: BV5S2 48-67
Chemical type: Peptide from protein
Sequence: QYYEEEERQRGNFPDRFSG
Position: 67-85
Source molecule (GenBank): AAB63910.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 10.0

Epitope: BV5S2 48-67
Chemical type: Peptide from protein
Sequence: QYYEEEERQRGNFPDRFSG
Position: 67-85
Source molecule (GenBank): AAB63910.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 10000.0

Epitope: BV5S2 58-78
Chemical type: Peptide from protein
Sequence: GNFPDRFSGHQFPNYSSELN
Position: 77-96
Source molecule (GenBank): AAB63910.1
Assay category: TCell
Result: Negative
Host:  33-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: BV5S2 58-78
Chemical type: Peptide from protein
Sequence: GNFPDRFSGHQFPNYSSELN
Position: 77-96
Source molecule (GenBank): AAB63910.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 2000.0

Epitope: BV5S2 58-78
Chemical type: Peptide from protein
Sequence: GNFPDRFSGHQFPNYSSELN
Position: 77-96
Source molecule (GenBank): AAB63910.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 10.0

Epitope: BV5S2 71-89
Chemical type: Peptide from protein
Sequence: PNYSSELNVNALLLGDSAL
Position: 89-107
Source molecule (GenBank): AAB63910.1
Assay category: TCell
Result: Negative
Host:  33-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: BV5S2 71-89
Chemical type: Peptide from protein
Sequence: PNYSSELNVNALLLGDSAL
Position: 89-107
Source molecule (GenBank): AAB63910.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 10.0

Epitope: BV5S2 71-89
Chemical type: Peptide from protein
Sequence: PNYSSELNVNALLLGDSAL
Position: 89-107
Source molecule (GenBank): AAB63910.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 10.0

Epitope: BV5S2 80-95
Chemical type: Peptide from protein
Sequence: NALLLGDSALYLCASS
Position: 98-113
Source molecule (GenBank): AAB63910.1
Assay category: TCell
Result: Negative
Host:  33-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: BV5S2 80-95
Chemical type: Peptide from protein
Sequence: NALLLGDSALYLCASS
Position: 98-113
Source molecule (GenBank): AAB63910.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 2000.0

Epitope: BV9 38-58
Chemical type: Peptide from protein
Sequence: SKKFLKIMFSYNNKELIINET
Position: 65-85
Source molecule (GenBank): BAF94979.1
Assay category: TCell
Result: Positive
Host:  33-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: BV3 11-30
Chemical type: Peptide from protein
Sequence: LVKRTGEKVFLECVQDMDHE
Position: 33-52
Source molecule (GenBank): BAF94971.1
Assay category: TCell
Result: Negative
Host:  33-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: BV3 38-58
Chemical type: Peptide from protein
Sequence: DPGLGLRLIYFSYDVKMKEKG
Position: 60-80
Source molecule (GenBank): BAF94971.1
Assay category: TCell
Result: Positive
Host:  33-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: BV12S2 38-58
Chemical type: Peptide from protein
Sequence: DPGHGLRLIHYSYGVKDTDKG
Position: 63-83
Source molecule (GenBank): BAF94934.1
Assay category: TCell
Result: Positive
Host:  33-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: BV5S2 38-58(Y49T)
Chemical type: Peptide, no natural source
Sequence: ALGQGPQFIFQTYEEEERQRG
Assay category: TCell
Result: Positive
Host:  33-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: BV5S2 38-58(Y49T)
Chemical type: Peptide, no natural source
Sequence: ALGQGPQFIFQTYEEEERQRG
Assay category: TCell
Result: Positive
Host:  33-66 years
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated