Reference: Isolda A Popova; Lizelle Lubbe; Pavel A Petukhov; Gavriil F Kalantarov; Ilya N Trakht; Elena R Chernykh; Olga Y Leplina; Alex V Lyubimov; Joe G N Garcia; Steven M Dudek; Edward D Sturrock; Sergei M Danilov. "Epitope mapping of novel monoclonal antibodies to human angiotensin I-converting enzyme." Protein science : a publication of the Protein Society (2021).

Epitope: Epitope of mAb 5B3 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: Q47, L48, Q51, Q116
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.3

Epitope: Epitope of mAb 5B3 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: Q47, L48, Q51, Q116
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 5B3 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: Q47, L48, Q51, Q116
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb 2D7 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: D171, M184, L313
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 2D7 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: D171, M184, L313
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb 2D7 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: D171, M184, L313
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb 2D7 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: D171, M184, L313
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of mAb 2D7 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: D171, M184, L313
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb 2D7 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: D171, M184, L313
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive
Quantitative measurement: 6.0

Epitope: Epitope of mAb 6H6 and 6C8 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: R561
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 124.0

Epitope: Epitope of mAb 6H6 and 6C8 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: R561
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.5

Epitope: Epitope of mAb 6H6 and 6C8 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: R561
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 2D1 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: K136
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 2D1 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: K136
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 42.0

Epitope: Epitope of mAb 2D1 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: K136
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 3C10 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: S650, K651, N710, Q711, L712
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb 3C10 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: S650, K651, N710, Q711, L712
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of mAb 3C10 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: S650, K651, N710, Q711, L712
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of mAb 3C10 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: S650, K651, N710, Q711, L712
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb 3C10 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: S650, K651, N710, Q711, L712
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of mAb 3C10 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: S650, K651, N710, Q711, L712
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.3

Epitope: Epitope of mAb 3C10 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: S650, K651, N710, Q711, L712
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 5G8 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: D782
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 5G8 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: D782
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of mAb 5G8 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: D782
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.4

Epitope: Epitope of mAb 5G8 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: D782
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 8H1 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: T916
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.3

Epitope: Epitope of mAb 8H1 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: T916
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 8H1 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: T916
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb 8H1 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: T916
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb 4C12 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: A866, Q867, H868
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 4C12 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: A866, Q867, H868
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 4C12 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: A866, Q867, H868
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 4C12 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: A866, Q867, H868
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 9B9 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: N38, F39, S40, A41, R369
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of mAb 9B9 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: N38, F39, S40, A41, R369
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of mAb 9B9 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: N38, F39, S40, A41, R369
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.6

Epitope: Epitope of mAb 9B9 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: N38, F39, S40, A41, R369
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of mAb 9B9 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: N38, F39, S40, A41, R369
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 9B9 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: N38, F39, S40, A41, R369
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 9B9 on ACE 1
Chemical type: Discontinuous protein residues
Discontinuous residues: N38, F39, S40, A41, R369
Source molecule (GenBank): P12821.1
Assay category: BCell
Result: Positive