Reference: Wael Awad; Geraldine J M Ler; Weijun Xu; Andrew N Keller; Jeffrey Y W Mak; Xin Yi Lim; Ligong Liu; Sidonia B G Eckle; Jérôme Le Nours; James McCluskey; Alexandra J Corbett; David P Fairlie; Jamie Rossjohn. "The molecular basis underpinning the potency and specificity of MAIT cell antigens." Nature immunology (2020).

Epitope: 5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 2200.0

Epitope: 5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 2700.0

Epitope: 5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 2.08

Epitope: 5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive-High
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: 5-OP-RU
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 56.5

Epitope: 5-OP-RU
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.85

Epitope: 5-OP-RU
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 88.0

Epitope: JYM72
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 2.08

Epitope: JYM72
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: JYM72
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 10700.0

Epitope: JYM72
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JYM72
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 24100.0

Epitope: JYM72
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 57.9

Epitope: JYM72
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.08

Epitope: JYM72
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 6000.0

Epitope: 5′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 1.92

Epitope: 5′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 3700.0

Epitope: 5′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 16900.0

Epitope: 5′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 5′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive-High
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: 5′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 5′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 5′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.92

Epitope: 5′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 162.0

Epitope: 4′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 1.9

Epitope: 4′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 4300.0

Epitope: 4′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 14900.0

Epitope: 4′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 4′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive-High
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: 4′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 4′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 4′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.9

Epitope: 4′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 69.0

Epitope: 3′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 1.84

Epitope: 3′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 3′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 3′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 25100.0

Epitope: 3′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 53600.0

Epitope: 3′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 3′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: 3′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 300.0

Epitope: 3′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 53.3

Epitope: 3′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.84

Epitope: 2′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 1.96

Epitope: 2′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 2′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 2′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 35100.0

Epitope: 2′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 64100.0

Epitope: 2′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 2′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: 2′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 49.0

Epitope: 2′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 52.4

Epitope: 2′-D-5-OP-RU
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.96

Epitope: Ribityl-less analogue of JYM72
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 1.88

Epitope: Ribityl-less analogue of JYM72
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 97500.0

Epitope: Ribityl-less analogue of JYM72
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ribityl-less analogue of JYM72
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive-Low
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: Ribityl-less analogue of JYM72
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ribityl-less analogue of JYM72
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ribityl-less analogue of JYM72
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 6000.0

Epitope: Ribityl-less analogue of JYM72
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 59.7

Epitope: Ribityl-less analogue of JYM72
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.88

Epitope: 5′-OH-pentyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 1.8

Epitope: 5′-OH-pentyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 5′-OH-pentyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: 5′-OH-pentyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 5′-OH-pentyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 5′-OH-pentyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 49.0

Epitope: 5′-OH-pentyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.8

Epitope: 3′-OH-propyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 1.92

Epitope: 3′-OH-propyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 60200.0

Epitope: 3′-OH-propyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 3′-OH-propyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive-Low
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: 3′-OH-propyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 61.0

Epitope: 3′-OH-propyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.92

Epitope: 2′-OH-ethyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 1.8

Epitope: 2′-OH-ethyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 25200.0

Epitope: 2′-OH-ethyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Quantitative measurement: 60500.0

Epitope: 2′-OH-ethyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 2′-OH-ethyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: 2′-OH-ethyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 35.0

Epitope: 2′-OH-ethyl-5- OP-U
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.8

Epitope: 5'-D-RL-7-Me
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: 5'-D-RL-7-Me
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive-Low

Epitope: 5'-OH-pentyl-L-7-Me
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: 5'-OH-pentyl-L-7-Me
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive-Low

Epitope: 4'-D-RL-6-Me
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: 4'-D-RL-6-Me
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive-Low

Epitope: 4'-D-RL-7-Me
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: 4'-D-RL-7-Me
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive-Low

Epitope: 4'-OH-butyl-L-6-Me
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: 4'-OH-butyl-L-6-Me
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive

Epitope: 4'-OH-butyl-L-7-Me
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: 4'-OH-butyl-L-7-Me
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive

Epitope: 2'-D-RL-7-Me
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive-Low
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: 2'-D-RL-7-Me
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive-Low

Epitope: Ac-6-FP
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: Ac-6-FP
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 6000.0

Epitope: Ac-6-FP
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 63.6

Epitope: RL-7-Me
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: RL-7-Me
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Negative