Reference: Pengju Yao; Mingjie Gao; Weiyi Hu; Jiahao Wang; Yuhao Wang; Qingsong Wang; Jianguo Ji. "Proteogenomic analysis identifies neoantigens and bacterial peptides as immunotherapy targets in colorectal cancer." Pharmacological research (2024).

Epitope: T2-1
Chemical type: Peptide from protein
Sequence: GYVLGAPLV
Position: 281-289
Source molecule (GenBank): Q86UG4.2
Assay category: TCell
Result: Negative
MHC allele types: 143 544 37 43 305 582
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T2-1
Chemical type: Peptide from protein
Sequence: GYVLGAPLV
Position: 281-289
Source molecule (GenBank): Q86UG4.2
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 143 544 37 43 305 582

Epitope: T2-2
Chemical type: Peptide from protein
Sequence: IMKKIRESY
Position: 343-351
Source molecule (GenBank): O00425.2
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 143 544 37 43 305 582

Epitope: T2-3
Chemical type: Peptide from protein
Sequence: KISGGPRISY
Position: 292-301
Source molecule (GenBank): P43360.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 143 544 37 43 305 582

Epitope: T2-4
Chemical type: Peptide from protein
Sequence: QSPQGASSL
Position: 63-71
Source molecule (GenBank): P43357.1
Assay category: TCell
Result: Negative
MHC allele types: 143 544 37 43 305 582
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T2-4
Chemical type: Peptide from protein
Sequence: QSPQGASSL
Position: 63-71
Source molecule (GenBank): P43357.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 143 544 37 43 305 582

Epitope: T2-6
Chemical type: Peptide from protein
Sequence: SFYEHIITV
Position: 347-355
Source molecule (GenBank): Q5T6F0.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 143 544 37 43 305 582

Epitope: T3-1
Chemical type: Peptide from protein
Sequence: LDRRCQLNV
Position: 156-164
Source molecule (GenBank): A0A0A6YYL3.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 211 215 257 39 305 311

Epitope: T3-2
Chemical type: Peptide from protein
Sequence: GQHLHLETF
Position: 89-97
Source molecule (GenBank): P78395.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 211 215 257 39 305 311

Epitope: T5-1
Chemical type: Peptide from protein
Sequence: CEKHLQAL
Position: 61-68
Source molecule (GenBank): Q07617.3
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 213 215 40 28 308 7

Epitope: T5-2
Chemical type: Peptide from protein
Sequence: IEKDPSLVYQHL
Position: 862-873
Source molecule (GenBank): Q07617.3
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 213 215 40 28 308 7

Epitope: T5-3
Chemical type: Peptide from protein
Sequence: ISKGQKELIEQL
Position: 889-900
Source molecule (GenBank): Q07617.3
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 213 215 40 28 308 7

Epitope: T5-4
Chemical type: Peptide from protein
Sequence: IYTNRALCY
Position: 659-667
Source molecule (GenBank): Q07617.3
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 213 215 40 28 308 7

Epitope: T5-5
Chemical type: Peptide from protein
Sequence: KGKRMVIQEI
Position: 335-344
Source molecule (GenBank): Q07617.3
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 213 215 40 28 308 7

Epitope: T5-6
Chemical type: Peptide from protein
Sequence: ASIEVTLAK
Position: 299-307
Source molecule (GenBank): Q8TBY0.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 213 215 40 28 308 7

Epitope: T5-7
Chemical type: Peptide from protein
Sequence: AHCLYSEEL
Position: 107-115
Source molecule (GenBank): Q6UWB4.2
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 213 215 40 28 308 7

Epitope: T5-8
Chemical type: Peptide from protein
Sequence: QSENLKQSI
Position: 306-314
Source molecule (GenBank): Q15431.2
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 213 215 40 28 308 7

Epitope: T5-9
Chemical type: Peptide from protein
Sequence: KCYKLPLF
Position: 574-581
Source molecule (GenBank): Q86UG4.2
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 213 215 40 28 308 7

Epitope: T5-10
Chemical type: Peptide from protein
Sequence: AIIGKQGQHIK
Position: 419-429
Source molecule (GenBank): O00425.2
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 213 215 40 28 308 7

Epitope: T6-1
Chemical type: Peptide from protein
Sequence: AETTGLIKL
Position: 174-182
Source molecule (GenBank): Q8NI51.2
Assay category: TCell
Result: Positive
MHC allele types: 215 204 28 45 305 308
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T6-1
Chemical type: Peptide from protein
Sequence: AETTGLIKL
Position: 174-182
Source molecule (GenBank): Q8NI51.2
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 215 204 28 45 305 308

Epitope: T6-2
Chemical type: Peptide from protein
Sequence: SEVDKTKEEL
Position: 949-958
Source molecule (GenBank): Q96PC5.4
Assay category: TCell
Result: Negative
MHC allele types: 215 204 28 45 305 308
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T6-2
Chemical type: Peptide from protein
Sequence: SEVDKTKEEL
Position: 949-958
Source molecule (GenBank): Q96PC5.4
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 215 204 28 45 305 308

Epitope: T7-1
Chemical type: Peptide from protein
Sequence: LPVDKTIQA
Position: 936-944
Source molecule (GenBank): Q9BXT4.2
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 215 45 41 305 8

Epitope: T7-N1
Chemical type: Peptide, no natural source
Sequence: TPITTTITV
Assay category: TCell
Result: Positive
MHC allele types: 215 45 41 305 8
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T7-N1
Chemical type: Peptide, no natural source
Sequence: TPITTTITV
Assay category: TCell
Result: Positive
MHC allele types: 215 45 41 305 8
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T7-W1
Chemical type: Peptide from protein
Sequence: TPITTTTTV
Position: 1896-1904
Source molecule (GenBank): Q02817.3
Assay category: TCell
Result: Negative
MHC allele types: 215 45 41 305 8
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T7-W1
Chemical type: Peptide from protein
Sequence: TPITTTTTV
Position: 1896-1904
Source molecule (GenBank): Q02817.3
Assay category: TCell
Result: Negative
MHC allele types: 215 45 41 305 8
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T7-B6
Chemical type: Peptide from protein
Sequence: NPVTGIVEA
Position: 231-239
Source molecule (GenBank): A0A1G8BXS4
Assay category: TCell
Result: Positive
MHC allele types: 215 45 41 305 8
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T7-B7
Chemical type: Peptide from protein
Sequence: KAEPATVTI
Position: 1301-1309
Source molecule (GenBank): B0G9H7
Assay category: TCell
Result: Positive
MHC allele types: 215 45 41 305 8
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T8-N1
Chemical type: Peptide, no natural source
Sequence: ASTITHDLY
Assay category: TCell
Result: Positive
MHC allele types: 142 215 38 45 1 305
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T8-N1
Chemical type: Peptide, no natural source
Sequence: ASTITHDLY
Assay category: TCell
Result: Positive
MHC allele types: 142 215 38 45 1 305
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: T8-N1
Chemical type: Peptide, no natural source
Sequence: ASTITHDLY
Assay category: TCell
Result: Positive
MHC allele types: 142 215 38 45 1 305
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T8-N1
Chemical type: Peptide, no natural source
Sequence: ASTITHDLY
Assay category: MhcBinding
Result: Negative

Epitope: T8-N1
Chemical type: Peptide, no natural source
Sequence: ASTITHDLY
Assay category: MhcBinding
Result: Negative

Epitope: T8-N1
Chemical type: Peptide, no natural source
Sequence: ASTITHDLY
Assay category: MhcBinding
Result: Negative

Epitope: T8-N1
Chemical type: Peptide, no natural source
Sequence: ASTITHDLY
Assay category: MhcBinding
Result: Negative

Epitope: T8-N1
Chemical type: Peptide, no natural source
Sequence: ASTITHDLY
Assay category: MhcBinding
Result: Positive

Epitope: T8-W1
Chemical type: Peptide from protein
Sequence: ASTITHGLY
Position: 159-167
Source molecule (GenBank): O43557.2
Assay category: TCell
Result: Negative
MHC allele types: 142 215 38 45 1 305
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T8-W1
Chemical type: Peptide from protein
Sequence: ASTITHGLY
Position: 159-167
Source molecule (GenBank): O43557.2
Assay category: TCell
Result: Positive
MHC allele types: 142 215 38 45 1 305
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T6/T8-B5
Chemical type: Peptide from protein
Sequence: IEREELHKL
Position: 262-270
Source molecule (GenBank): Q64XM1
Assay category: TCell
Result: Positive
MHC allele types: 142 215 38 45 1 305
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T6/T8-B5
Chemical type: Peptide from protein
Sequence: IEREELHKL
Position: 262-270
Source molecule (GenBank): Q64XM1
Assay category: TCell
Result: Positive
MHC allele types: 142 215 38 45 1 305
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: T6/T8-B5
Chemical type: Peptide from protein
Sequence: IEREELHKL
Position: 262-270
Source molecule (GenBank): Q64XM1
Assay category: TCell
Result: Positive
MHC allele types: 142 215 38 45 1 305 204 28 308
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T6/T8-B5
Chemical type: Peptide from protein
Sequence: IEREELHKL
Position: 262-270
Source molecule (GenBank): Q64XM1
Assay category: MhcBinding
Result: Negative

Epitope: T6/T8-B5
Chemical type: Peptide from protein
Sequence: IEREELHKL
Position: 262-270
Source molecule (GenBank): Q64XM1
Assay category: MhcBinding
Result: Negative

Epitope: T6/T8-B5
Chemical type: Peptide from protein
Sequence: IEREELHKL
Position: 262-270
Source molecule (GenBank): Q64XM1
Assay category: MhcBinding
Result: Negative

Epitope: T6/T8-B5
Chemical type: Peptide from protein
Sequence: IEREELHKL
Position: 262-270
Source molecule (GenBank): Q64XM1
Assay category: MhcBinding
Result: Positive

Epitope: T6/T8-B5
Chemical type: Peptide from protein
Sequence: IEREELHKL
Position: 262-270
Source molecule (GenBank): Q64XM1
Assay category: MhcBinding
Result: Negative

Epitope: T8-B8
Chemical type: Peptide from protein
Sequence: KEFPNAVTV
Position: 446-454
Source molecule (GenBank): R5RHM8
Assay category: TCell
Result: Positive
MHC allele types: 142 215 38 45 1 305
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T5-N1
Chemical type: Peptide, no natural source
Sequence: NHMAEPSL
Assay category: TCell
Result: Positive
MHC allele types: 213 215 40 28 308
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T5-W1
Chemical type: Peptide from protein
Sequence: NHTAEPSL
Position: 144-151
Source molecule (GenBank): Q9C0H2.3
Assay category: TCell
Result: Negative
MHC allele types: 213 215 40 28 308
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T3-B1
Chemical type: Peptide from protein
Sequence: SAYAGGAVY
Position: 153-161
Source molecule (GenBank): WP_005963459.1
Assay category: TCell
Result: Positive
MHC allele types: 211 215 257 39 305 311
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T3/T6-B2
Chemical type: Peptide from protein
Sequence: ISEGPLYLL
Position: 424-432
Source molecule (GenBank): F7LX89
Assay category: TCell
Result: Positive
MHC allele types: 211 215 257 39 305 311 204 28 45 308
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T6-B4
Chemical type: Peptide from protein
Sequence: LERALITNL
Position: 198-206
Source molecule (GenBank): A0A1Y3R3C6
Assay category: TCell
Result: Positive
MHC allele types: 215 204 28 45 305 308
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T8-N4
Chemical type: Peptide from protein
Sequence: IPRPQPAA
Position: 284-291
Source molecule (GenBank): ADM43482.1
Assay category: TCell
Result: Positive
MHC allele types: 142 215 38 45 1 305
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T8-N4
Chemical type: Peptide from protein
Sequence: IPRPQPAA
Position: 284-291
Source molecule (GenBank): ADM43482.1
Assay category: TCell
Result: Negative
MHC allele types: 142 215 38 45 1 305
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: T8-N4
Chemical type: Peptide from protein
Sequence: IPRPQPAA
Position: 284-291
Source molecule (GenBank): ADM43482.1
Assay category: MhcBinding
Result: Negative

Epitope: T8-N4
Chemical type: Peptide from protein
Sequence: IPRPQPAA
Position: 284-291
Source molecule (GenBank): ADM43482.1
Assay category: MhcBinding
Result: Negative

Epitope: T8-N4
Chemical type: Peptide from protein
Sequence: IPRPQPAA
Position: 284-291
Source molecule (GenBank): ADM43482.1
Assay category: MhcBinding
Result: Negative

Epitope: T8-N4
Chemical type: Peptide from protein
Sequence: IPRPQPAA
Position: 284-291
Source molecule (GenBank): ADM43482.1
Assay category: MhcBinding
Result: Negative

Epitope: T8-N4
Chemical type: Peptide from protein
Sequence: IPRPQPAA
Position: 284-291
Source molecule (GenBank): ADM43482.1
Assay category: MhcBinding
Result: Negative