Reference: Minghua Zheng; Lizhi Zhou; Yang Huang; Xiao Zhang; Zihao Yu; Chengyu Yang; Yuanzhi Chen; Dong Ying; Hong Wang; Zhenqin Chen; Chang Liu; Zimin Tang; Siling Wang; Kaihang Wang; Kaixiang Yang; Yanqing Lin; Tingting Li; Qingbing Zheng; Zizheng Zheng; Jun Zhang; Hai Yu; Shaowei Li; Ying Gu; Ningshao Xia. "Structural basis for the synergetic neutralization of hepatitis E virus by antibody-antibody interaction." Proceedings of the National Academy of Sciences of the United States of America (2024).

Epitope: Epitope of 8C11 Fab on HEV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T476, A477, Y485, D496, S497, V498, T499, V510, R512, S513, L514, D515, K534, N573, A574, A575, G576, H577, R578, P592
Source molecule (GenBank): BDX26000.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.48
Host:  6-8 weeks

Epitope: Epitope of 8C11 Fab on HEV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T476, A477, Y485, D496, S497, V498, T499, V510, R512, S513, L514, D515, K534, N573, A574, A575, G576, H577, R578, P592
Source molecule (GenBank): BDX26000.1
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: Epitope of 8C11 Fab on HEV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T476, A477, Y485, D496, S497, V498, T499, V510, R512, S513, L514, D515, K534, N573, A574, A575, G576, H577, R578, P592
Source molecule (GenBank): BDX26000.1
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: Epitope of 8C11 Fab on HEV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T476, A477, Y485, D496, S497, V498, T499, V510, R512, S513, L514, D515, K534, N573, A574, A575, G576, H577, R578, P592
Source molecule (GenBank): BDX26000.1
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: Epitope of 8C11 Fab on HEV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T476, A477, Y485, D496, S497, V498, T499, V510, R512, S513, L514, D515, K534, N573, A574, A575, G576, H577, R578, P592
Source molecule (GenBank): BDX26000.1
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: Epitope of 8C11 Fab on HEV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T476, A477, Y485, D496, S497, V498, T499, V510, R512, S513, L514, D515, K534, N573, A574, A575, G576, H577, R578, P592
Source molecule (GenBank): BDX26000.1
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: Epitope of 8C11 Fab on HEV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T476, A477, Y485, D496, S497, V498, T499, V510, R512, S513, L514, D515, K534, N573, A574, A575, G576, H577, R578, P592
Source molecule (GenBank): BDX26000.1
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: Epitope of 8C11 Fab on HEV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T476, A477, Y485, D496, S497, V498, T499, V510, R512, S513, L514, D515, K534, N573, A574, A575, G576, H577, R578, P592
Source molecule (GenBank): BDX26000.1
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: Epitope of 8H3 Fab on HEV E2
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E549, T552, T553, K554, T586, G589; B: S527, T528, I529, Q530, Q531, H532, V538, N560, T563, T564, A565, S566, Q568
Source molecule (GenBank): BDX26000.1
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: Epitope of 8H3 Fab on HEV E2
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E549, T552, T553, K554, T586, G589; B: S527, T528, I529, Q530, Q531, H532, V538, N560, T563, T564, A565, S566, Q568
Source molecule (GenBank): BDX26000.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.48
Host:  6-8 weeks

Epitope: Epitope of 8H3 Fab on HEV E2
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E549, T552, T553, K554, T586, G589; B: S527, T528, I529, Q530, Q531, H532, V538, N560, T563, T564, A565, S566, Q568
Source molecule (GenBank): BDX26000.1
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: Epitope of 8H3 Fab on HEV E2
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E549, T552, T553, K554, T586, G589; B: S527, T528, I529, Q530, Q531, H532, V538, N560, T563, T564, A565, S566, Q568
Source molecule (GenBank): BDX26000.1
Assay category: BCell
Result: Positive-Intermediate
Host:  6-8 weeks

Epitope: Epitope of 8H3 Fab on HEV E2
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E549, T552, T553, K554, T586, G589; B: S527, T528, I529, Q530, Q531, H532, V538, N560, T563, T564, A565, S566, Q568
Source molecule (GenBank): BDX26000.1
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: Epitope of 8H3 Fab on HEV E2
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E549, T552, T553, K554, T586, G589; B: S527, T528, I529, Q530, Q531, H532, V538, N560, T563, T564, A565, S566, Q568
Source molecule (GenBank): BDX26000.1
Assay category: BCell
Result: Positive-Intermediate
Host:  6-8 weeks

Epitope: Epitope of 8H3 Fab on HEV E2
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E549, T552, T553, K554, T586, G589; B: S527, T528, I529, Q530, Q531, H532, V538, N560, T563, T564, A565, S566, Q568
Source molecule (GenBank): BDX26000.1
Assay category: BCell
Result: Positive-Low
Host:  6-8 weeks