Reference: K W Wucherpfennig; A Sette; S Southwood; C Oseroff; M Matsui; J L Strominger; D A Hafler. "Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones." The Journal of experimental medicine (1994).

Epitope: (84-102)Y
Chemical type: Peptide, no natural source
Sequence: DENPVVHFFKNIVTPRTPPY
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 5.7

Epitope: (85-102)Y
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFKNIVTPRTPPY
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 10.0

Epitope: (85-102)Y
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFKNIVTPRTPPY
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 690.0

Epitope: (86-102)Y
Chemical type: Peptide, no natural source
Sequence: NPVVHFFKNIVTPRTPPY
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 8.6

Epitope: (86-102)Y
Chemical type: Peptide, no natural source
Sequence: NPVVHFFKNIVTPRTPPY
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 140.0

Epitope: (87-102)Y
Chemical type: Peptide, no natural source
Sequence: PVVHFFKNIVTPRTPPY
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2.7

Epitope: (87-102)Y
Chemical type: Peptide, no natural source
Sequence: PVVHFFKNIVTPRTPPY
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 51.0

Epitope: (88-102)Y
Chemical type: Peptide, no natural source
Sequence: VVHFFKNIVTPRTPPY
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 7.5

Epitope: (88-102)Y
Chemical type: Peptide, no natural source
Sequence: VVHFFKNIVTPRTPPY
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 51.0

Epitope: (89-102)Y
Chemical type: Peptide, no natural source
Sequence: VHFFKNIVTPRTPPY
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 47.0

Epitope: (89-102)Y
Chemical type: Peptide, no natural source
Sequence: VHFFKNIVTPRTPPY
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 55.0

Epitope: (90-102)Y
Chemical type: Peptide, no natural source
Sequence: HFFKNIVTPRTPPY
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 405.0

Epitope: (90-102)Y
Chemical type: Peptide, no natural source
Sequence: HFFKNIVTPRTPPY
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 230.0

Epitope: (91-102)Y
Chemical type: Peptide, no natural source
Sequence: FFKNIVTPRTPPY
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 19500.0

Epitope: (91-102)Y
Chemical type: Peptide, no natural source
Sequence: FFKNIVTPRTPPY
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 3900.0

Epitope: (84-100)
Chemical type: Peptide from protein
Sequence: DENPVVHFFKNIVTPRT
Position: 92-108
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 19.0

Epitope: (84-100)
Chemical type: Peptide from protein
Sequence: DENPVVHFFKNIVTPRT
Position: 92-108
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 3200.0

Epitope: (84-99)
Chemical type: Peptide from protein
Sequence: DENPVVHFFKNIVTPR
Position: 92-107
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 12.0

Epitope: (84-99)
Chemical type: Peptide from protein
Sequence: DENPVVHFFKNIVTPR
Position: 92-107
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1350.0

Epitope: (84-97)
Chemical type: Peptide from protein
Sequence: DENPVVHFFKNIVT
Position: 92-105
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 4.6

Epitope: (84-97)
Chemical type: Peptide from protein
Sequence: DENPVVHFFKNIVT
Position: 92-105
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 810.0

Epitope: (84-96)
Chemical type: Peptide from protein
Sequence: DENPVVHFFKNIV
Position: 92-104
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 7.0

Epitope: (84-96)
Chemical type: Peptide from protein
Sequence: DENPVVHFFKNIV
Position: 92-104
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 2300.0

Epitope: (84-95)
Chemical type: Peptide from protein
Sequence: DENPVVHFFKNI
Position: 92-103
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 12.0

Epitope: (84-95)
Chemical type: Peptide from protein
Sequence: DENPVVHFFKNI
Position: 92-103
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 6900.0

Epitope: (84-94)
Chemical type: Peptide from protein
Sequence: DENPVVHFFKN
Position: 92-102
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 707.0

Epitope: (84-94)
Chemical type: Peptide from protein
Sequence: DENPVVHFFKN
Position: 92-102
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Negative

Epitope: (84-93)
Chemical type: Peptide from protein
Sequence: DENPVVHFFK
Position: 92-101
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 12000.0

Epitope: (84-93)
Chemical type: Peptide from protein
Sequence: DENPVVHFFK
Position: 92-101
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Negative

Epitope: (85-99)
Chemical type: Peptide from protein
Sequence: ENPVVHFFKNIVTPR
Position: 93-107
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 3.6

Epitope: (85-99)
Chemical type: Peptide from protein
Sequence: ENPVVHFFKNIVTPR
Position: 93-107
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 800.0

Epitope: (85-98,98A)
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFKNIVTA
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 12.0

Epitope: (85-98,98A)
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFKNIVTA
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 20000.0

Epitope: (86-99)
Chemical type: Peptide from protein
Sequence: NPVVHFFKNIVTPR
Position: 94-107
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 6.8

Epitope: (86-99)
Chemical type: Peptide from protein
Sequence: NPVVHFFKNIVTPR
Position: 94-107
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1200.0

Epitope: (86-98,98A)
Chemical type: Peptide, no natural source
Sequence: NPVVHFFKNIVTA
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 7.8

Epitope: (86-98,98A)
Chemical type: Peptide, no natural source
Sequence: NPVVHFFKNIVTA
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 30000.0

Epitope: (86-97)
Chemical type: Peptide from protein
Sequence: NPVVHFFKNIVT
Position: 94-105
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 26.0

Epitope: (86-97)
Chemical type: Peptide from protein
Sequence: NPVVHFFKNIVT
Position: 94-105
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 8000.0

Epitope: (87-99)
Chemical type: Peptide from protein
Sequence: PVVHFFKNIVTPR
Position: 95-107
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 16.0

Epitope: (87-99)
Chemical type: Peptide from protein
Sequence: PVVHFFKNIVTPR
Position: 95-107
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 5900.0

Epitope: (87-97)
Chemical type: Peptide from protein
Sequence: PVVHFFKNIVT
Position: 95-105
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Negative

Epitope: (87-97)
Chemical type: Peptide from protein
Sequence: PVVHFFKNIVT
Position: 95-105
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 395.0

Epitope: (89-99)
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPR
Position: 97-107
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1300.0

Epitope: (89-99)
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPR
Position: 97-107
Source molecule (GenBank): AAH08749.2
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1200.0

Epitope: MBP Y(80-103)
Chemical type: Peptide, no natural source
Sequence: YGRTQDENPVVHFFKNIVTPRTPPP
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 8.8

Epitope: TT(830-843)
Chemical type: Peptide from protein
Sequence: QYIKANSKFIGITE
Position: 88-101
Source molecule (GenBank): AAA23282.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 21.0

Epitope: (85-99)86A
Chemical type: Peptide, no natural source
Sequence: EAPVVHFFKNIVTPR
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2.2

Epitope: (85-99)86A
Chemical type: Peptide, no natural source
Sequence: EAPVVHFFKNIVTPR
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 940.0

Epitope: (85-99)87A
Chemical type: Peptide, no natural source
Sequence: ENAVVHFFKNIVTPR
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 610.0

Epitope: (85-99)87A
Chemical type: Peptide, no natural source
Sequence: ENAVVHFFKNIVTPR
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 3.1

Epitope: (85-99)88A
Chemical type: Peptide, no natural source
Sequence: ENPAVHFFKNIVTPR
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 1.1

Epitope: (85-99)88A
Chemical type: Peptide, no natural source
Sequence: ENPAVHFFKNIVTPR
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 945.0

Epitope: (85-99)90A
Chemical type: Peptide, no natural source
Sequence: ENPVVAFFKNIVTPR
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 1.9

Epitope: (85-99)90A
Chemical type: Peptide, no natural source
Sequence: ENPVVAFFKNIVTPR
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 640.0

Epitope: (85-99)91A
Chemical type: Peptide, no natural source
Sequence: ENPVVHAFKNIVTPR
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1300.0

Epitope: (85-99)91A
Chemical type: Peptide, no natural source
Sequence: ENPVVHAFKNIVTPR
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 3.8

Epitope: (85-99)92A
Chemical type: Peptide, no natural source
Sequence: ENPVVHFAKNIVTPR
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 283.0

Epitope: (85-99)92A
Chemical type: Peptide, no natural source
Sequence: ENPVVHFAKNIVTPR
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 8200.0

Epitope: (85-99)93A
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFANIVTPR
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 4.1

Epitope: (85-99)93A
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFANIVTPR
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 2900.0

Epitope: (85-99)94A
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFKAIVTPR
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 4.5

Epitope: (85-99)94A
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFKAIVTPR
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 140.0

Epitope: (85-99)95A
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFKNAVTPR
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2.1

Epitope: (85-99)95A
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFKNAVTPR
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1100.0

Epitope: (85-99)96A
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFKNIATPR
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2.7

Epitope: (85-99)96A
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFKNIATPR
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 730.0

Epitope: (85-99)99A
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFKNIVTPA
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2.3

Epitope: (85-99)99A
Chemical type: Peptide, no natural source
Sequence: ENPVVHFFKNIVTPA
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 2300.0