Reference: Yang Pan; John W Phillips; Beatrice D Zhang; Miyako Noguchi; Eric Kutschera; Jami McLaughlin; Pavlo A Nesterenko; Zhiyuan Mao; Nathanael J Bangayan; Robert Wang; Wendy Tran; Harry T Yang; Yuanyuan Wang; Yang Xu; Matthew B Obusan; Donghui Cheng; Alex H Lee; Kathryn E Kadash-Edmondson; Ameya Champhekar; Cristina Puig-Saus; Antoni Ribas; Robert M Prins; Christopher S Seet; Gay M Crooks; Owen N Witte; Yi Xing. "IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing." Proceedings of the National Academy of Sciences of the United States of America (2023).

Epitope: ELFNSIIPL
Chemical type: Peptide from protein
Sequence: ELFNSIIPL
Position: 1153-1161
Source molecule (GenBank): H0Y599.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RELFNSIIPL
Chemical type: Peptide from protein
Sequence: RELFNSIIPL
Position: 1152-1161
Source molecule (GenBank): H0Y599.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SLPGLSYNV
Chemical type: Peptide from protein
Sequence: SLPGLSYNV
Position: 340-348
Source molecule (GenBank): A0A0U1RQD2.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SLPGLSYNVSV
Chemical type: Peptide from protein
Sequence: SLPGLSYNVSV
Position: 340-350
Source molecule (GenBank): A0A0U1RQD2.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SLPETENSL
Chemical type: Peptide from protein
Sequence: SLPETENSL
Position: 655-663
Source molecule (GenBank): A0A0U1RR46.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: YTDMGRFTI
Chemical type: Peptide from protein
Sequence: YTDMGRFTI
Position: 111-119
Source molecule (GenBank): P54920.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HMGEGEVSL
Chemical type: Peptide, no natural source
Sequence: HMGEGEVSL
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KIWAFNKKL
Chemical type: Peptide from protein
Sequence: KIWAFNKKL
Position: 491-499
Source molecule (GenBank): V9GYZ6.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: YIINSNPEM
Chemical type: Peptide from protein
Sequence: YIINSNPEM
Position: 731-739
Source molecule (GenBank): A0A8I5KR65.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ALVLISIVI
Chemical type: Peptide from protein
Sequence: ALVLISIVI
Position: 607-615
Source molecule (GenBank): Q96CP6.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ALVLISIVICV
Chemical type: Peptide from protein
Sequence: ALVLISIVICV
Position: 607-617
Source molecule (GenBank): Q96CP6.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LVLISIVICV
Chemical type: Peptide from protein
Sequence: LVLISIVICV
Position: 608-617
Source molecule (GenBank): Q96CP6.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: VLISIVICV
Chemical type: Peptide from protein
Sequence: VLISIVICV
Position: 609-617
Source molecule (GenBank): Q96CP6.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: YLPLLTFGAL
Chemical type: Peptide, no natural source
Sequence: YLPLLTFGAL
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ALAGKPLSL
Chemical type: Peptide from protein
Sequence: ALAGKPLSL
Position: 135-143
Source molecule (GenBank): F5H6B6.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: FLWLGGALT
Chemical type: Peptide, no natural source
Sequence: FLWLGGALT
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: FLWLGGALTT
Chemical type: Peptide, no natural source
Sequence: FLWLGGALTT
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: IIQSASTAV
Chemical type: Peptide, no natural source
Sequence: IIQSASTAV
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: QMSPIIQSA
Chemical type: Peptide, no natural source
Sequence: QMSPIIQSA
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ATLDCDNLV
Chemical type: Peptide from protein
Sequence: ATLDCDNLV
Position: 86-94
Source molecule (GenBank): A0A024R7P0.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ELWNKHQEV
Chemical type: Peptide from protein
Sequence: ELWNKHQEV
Position: 1121-1129
Source molecule (GenBank): Q8WXG6.2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: FILTYWTPS
Chemical type: Peptide, no natural source
Sequence: FILTYWTPS
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: FLAIVFFASIV
Chemical type: Peptide, no natural source
Sequence: FLAIVFFASIV
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: FLLALERGT
Chemical type: Peptide, no natural source
Sequence: FLLALERGT
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: FLSELEPPA
Chemical type: Peptide from protein
Sequence: FLSELEPPA
Position: 703-711
Source molecule (GenBank): O95782.3
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Engineered

Epitope: FLSELEPPAP
Chemical type: Peptide from protein
Sequence: FLSELEPPAP
Position: 703-712
Source molecule (GenBank): O95782.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: FTVTVTEPPV
Chemical type: Peptide from protein
Sequence: FTVTVTEPPV
Position: 979-988
Source molecule (GenBank): O75147.4
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GLLKMQRMLV
Chemical type: Peptide, no natural source
Sequence: GLLKMQRMLV
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GLSSHEELL
Chemical type: Peptide from protein
Sequence: GLSSHEELL
Position: 113-121
Source molecule (GenBank): K7EJR6.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HLPGVLHII
Chemical type: Peptide, no natural source
Sequence: HLPGVLHII
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ITITGMYAA
Chemical type: Peptide from protein
Sequence: ITITGMYAA
Position: 147-155
Source molecule (GenBank): Q86X29-6
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KLFPGEWGL
Chemical type: Peptide, no natural source
Sequence: KLFPGEWGL
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KLLKVLILM
Chemical type: Peptide, no natural source
Sequence: KLLKVLILM
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KLTAQVEEL
Chemical type: Peptide from protein
Sequence: KLTAQVEEL
Position: 1532-1540
Source molecule (GenBank): Q14980-2.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KMRIRAFPV
Chemical type: Peptide from protein
Sequence: KMRIRAFPV
Position: 15-23
Source molecule (GenBank): Q13618-3.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KSLAAGVWGL
Chemical type: Peptide from protein
Sequence: KSLAAGVWGL
Position: 152-161
Source molecule (GenBank): D4PHA4.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LLCPALGMTV
Chemical type: Peptide from protein
Sequence: LLCPALGMTV
Position: 50-59
Source molecule (GenBank): Q8NHE4-2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LLGIAKLLKV
Chemical type: Peptide, no natural source
Sequence: LLGIAKLLKV
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LLLGIAKLL
Chemical type: Peptide, no natural source
Sequence: LLLGIAKLL
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LLLGIAKLLKV
Chemical type: Peptide, no natural source
Sequence: LLLGIAKLLKV
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Engineered

Epitope: LLMPSRGTYL
Chemical type: Peptide from protein
Sequence: LLMPSRGTYL
Position: 135-144
Source molecule (GenBank): F8W9Y9.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LMPSRGTYL
Chemical type: Peptide from protein
Sequence: LMPSRGTYL
Position: 136-144
Source molecule (GenBank): F8W9Y9.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: QLRNSVLPV
Chemical type: Peptide from protein
Sequence: QLRNSVLPV
Position: 1602-1610
Source molecule (GenBank): Q8WWI1-2.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: QLYPENSEQV
Chemical type: Peptide from protein
Sequence: QLYPENSEQV
Position: 162-171
Source molecule (GenBank): O43709-2.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SLAAGVWGL
Chemical type: Peptide from protein
Sequence: SLAAGVWGL
Position: 153-161
Source molecule (GenBank): D4PHA4.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SLHSLKNRV
Chemical type: Peptide from protein
Sequence: SLHSLKNRV
Position: 392-400
Source molecule (GenBank): Q99081-3.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SQLRNSVLPV
Chemical type: Peptide from protein
Sequence: SQLRNSVLPV
Position: 1601-1610
Source molecule (GenBank): Q8WWI1-2.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: STMYYLWML
Chemical type: Peptide, no natural source
Sequence: STMYYLWML
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Engineered

Epitope: STMYYLWMLA
Chemical type: Peptide, no natural source
Sequence: STMYYLWMLA
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TLPSPDSFLI
Chemical type: Peptide from protein
Sequence: TLPSPDSFLI
Position: 124-133
Source molecule (GenBank): H0YDW2.8
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TMPSKSYGI
Chemical type: Peptide from protein
Sequence: TMPSKSYGI
Position: 73-81
Source molecule (GenBank): H0YB16.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TMYYLWMLA
Chemical type: Peptide, no natural source
Sequence: TMYYLWMLA
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: VSTMYYLWML
Chemical type: Peptide, no natural source
Sequence: VSTMYYLWML
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: YLEAKADLV
Chemical type: Peptide from protein
Sequence: YLEAKADLV
Position: 207-215
Source molecule (GenBank): Q96N19-3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: YLLCPALGM
Chemical type: Peptide from protein
Sequence: YLLCPALGM
Position: 49-57
Source molecule (GenBank): Q8NHE4-2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: YLLCPALGMT
Chemical type: Peptide from protein
Sequence: YLLCPALGMT
Position: 49-58
Source molecule (GenBank): Q8NHE4-2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: YLLCPALGMTV
Chemical type: Peptide from protein
Sequence: YLLCPALGMTV
Position: 49-59
Source molecule (GenBank): Q8NHE4-2
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: YQEPLHLPGV
Chemical type: Peptide from protein
Sequence: YQEPLHLPGV
Position: 420-429
Source molecule (GenBank): P05165.4
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: YTMPSKSYGI
Chemical type: Peptide from protein
Sequence: YTMPSKSYGI
Position: 72-81
Source molecule (GenBank): H0YB16.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: YVASEEAFV
Chemical type: Peptide from protein
Sequence: YVASEEAFV
Position: 172-180
Source molecule (GenBank): P09497.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ALRQYQQGV
Chemical type: Peptide from protein
Sequence: ALRQYQQGV
Position: 204-212
Source molecule (GenBank): Q9BYM8-4
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RLSIEGNIGL
Chemical type: Peptide from protein
Sequence: RLSIEGNIGL
Position: 40-49
Source molecule (GenBank): Q16854-6
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AMAPIKVRL
Chemical type: Peptide from protein
Sequence: AMAPIKVRL
Position: 52-60
Source molecule (GenBank): P30044-4.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: YYLWMLAGSL
Chemical type: Peptide from protein
Sequence: YYLWMLAGSL
Position: 168-177
Source molecule (GenBank): XP_047274227.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: QLSRHWGEPV
Chemical type: Peptide from protein
Sequence: QLSRHWGEPV
Position: 554-563
Source molecule (GenBank): XP_011513488.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: YLWMLAGSLL
Chemical type: Peptide from protein
Sequence: YLWMLAGSLL
Position: 169-178
Source molecule (GenBank): XP_047274227.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: FLFAPMLVEL
Chemical type: Peptide from protein
Sequence: FLFAPMLVEL
Position: 390-399
Source molecule (GenBank): XP_054174765.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: FLFAPMLVELA
Chemical type: Peptide from protein
Sequence: FLFAPMLVELA
Position: 390-400
Source molecule (GenBank): XP_054174765.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MLAGSLLWWC
Chemical type: Peptide from protein
Sequence: MLAGSLLWWC
Position: 172-181
Source molecule (GenBank): XP_047274227.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: YLWMLAGSL
Chemical type: Peptide from protein
Sequence: YLWMLAGSL
Position: 169-177
Source molecule (GenBank): XP_047274227.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ALHGENHARV
Chemical type: Peptide, no natural source
Sequence: ALHGENHARV
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated