Reference: Thomas Delong; Timothy A Wiles; Rocky L Baker; Brenda Bradley; Gene Barbour; Richard Reisdorph; Michael Armstrong; Roger L Powell; Nichole Reisdorph; Nitesh Kumar; Colleen M Elso; Megan DeNicola; Rita Bottino; Alvin C Powers; David M Harlan; Sally C Kent; Stuart I Mannering; Kathryn Haskins. "Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion." Science (New York, N.Y.) (2016).

Epitope: GDLQTLWSRMD
Chemical type: Peptide, no natural source
Sequence: RRAGDLQTLWSRMDARR
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: LQTLALWSRMD
Chemical type: Peptide, no natural source
Sequence: RRALQTLALWSRMDARR
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: LQTLALNAARD
Chemical type: Peptide, no natural source
Sequence: RRALQTLALNAARDARR
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: 2.5HIP
Chemical type: Peptide, no natural source
Sequence: EVEDPQVAQLELGGGPGAGDLQTLALWSRMDQLAKELTAE
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: 2.5HIP
Chemical type: Peptide, no natural source
Sequence: EVEDPQVAQLELGGGPGAGDLQTLALWSRMDQLAKELTAE
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: 2.5HIP
Chemical type: Peptide, no natural source
Sequence: EVEDPQVAQLELGGGPGAGDLQTLALWSRMDQLAKELTAE
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: 6.5HIP
Chemical type: Peptide, no natural source
Sequence: EVEDPQVAQLELGGGPGAGDLQTLALNAARDPNRESLDFLLV
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: pS3
Chemical type: Peptide, no natural source
Sequence: SRLGLWVRME
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: pS3
Chemical type: Peptide, no natural source
Sequence: SRLGLWVRME
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: 2.5mi
Chemical type: Peptide, no natural source
Sequence: AHHPIWARMDA
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: 2.5mi
Chemical type: Peptide, no natural source
Sequence: AHHPIWARMDA
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: HEL
Chemical type: Peptide from protein
Sequence: MKRHGLDNYRGYSL
Position: 30-43
Source molecule (GenBank): P00698.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: HEL
Chemical type: Peptide from protein
Sequence: MKRHGLDNYRGYSL
Position: 30-43
Source molecule (GenBank): P00698.1
Assay category: TCell
Result: Negative
Host: F 
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: hEGGG:NPY
Chemical type: Peptide, no natural source
Sequence: GQVELGGGSSPETLI
Assay category: TCell
Result: Positive
MHC allele types: 341 91
Host: M 20 years
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone

Epitope: hEGGG:IAPP2
Chemical type: Peptide, no natural source
Sequence: GQVELGGGNAVEVLK
Assay category: TCell
Result: Positive
Host: M 19 years
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone

Epitope: Proinsulin (37-54)
Chemical type: Peptide, no natural source
Sequence: LQVELGGGPGAGSLQ
Assay category: TCell
Result: Positive-Low
Host: M 19 years
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone