Reference: Amanda L Huff; S Daniel Haldar; Alexander A Gergis; Hejia Henry Wang; Ludmila Danilova; Thatcher Heumann; Maureen Berg; Yuxuan Wang; Lalitya Andaloori; Alexei Hernandez; Gabriella Longway; Benjamin Barrett; Zirui Zhu; Emily Davis-Marcisak; Christopher Thoburn; James Leatherman; Sarah Mitchell; Jae W Lee; Daniel H Shu; Maximillian F Konig; Brian J Mog; Janelle Montagne; Erin M Coyne; Katherine Bever; Marina Baretti; Mark Yarchoan; Robert A Anders; Luciane T Kagohara; Daniel Laheru; Amy M Thomas; Jennifer Durham; Julie M Nauroth; Jiayun Lu; Hao Wang; Elana J Fertig; Won Jin Ho; Nilofer S Azad; Elizabeth M Jaffee; Neeha Zaidi. "Mutant KRAS vaccine with dual checkpoint blockade in resected pancreatic cancer: a phase I trial." Nature communications (2026).

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: YKLVVVGAVGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: YKLVVVGAVGVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: YKLVVVGAVGVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: YKLVVVGAVGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: YKLVVVGAVGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: YKLVVVGAVGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: YKLVVVGAVGVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: YKLVVVGAVGVGKSALTIQLI
Assay category: TCell
Result: Positive-Low
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: YKLVVVGAVGVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: YKLVVVGAVGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: YKLVVVGAVGVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: YKLVVVGAVGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: YKLVVVGAVGVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: YKLVVVGAVGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G12V
Chemical type: Neo-epitope
Sequence: YKLVVVGAVGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G12A
Chemical type: Neo-epitope
Sequence: YKLVVVGAAGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12A
Chemical type: Neo-epitope
Sequence: YKLVVVGAAGVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12A
Chemical type: Neo-epitope
Sequence: YKLVVVGAAGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12A
Chemical type: Neo-epitope
Sequence: YKLVVVGAAGVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12A
Chemical type: Neo-epitope
Sequence: YKLVVVGAAGVGKSALTIQLI
Assay category: TCell
Result: Positive-Low
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12A
Chemical type: Neo-epitope
Sequence: YKLVVVGAAGVGKSALTIQLI
Assay category: TCell
Result: Positive-Low
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12A
Chemical type: Neo-epitope
Sequence: YKLVVVGAAGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12A
Chemical type: Neo-epitope
Sequence: YKLVVVGAAGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G12A
Chemical type: Neo-epitope
Sequence: YKLVVVGAAGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12A
Chemical type: Neo-epitope
Sequence: YKLVVVGAAGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G12A
Chemical type: Neo-epitope
Sequence: YKLVVVGAAGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G12A
Chemical type: Neo-epitope
Sequence: YKLVVVGAAGVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G12R
Chemical type: Neo-epitope
Sequence: YKLVVVGARGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12R
Chemical type: Neo-epitope
Sequence: YKLVVVGARGVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12R
Chemical type: Neo-epitope
Sequence: YKLVVVGARGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12R
Chemical type: Neo-epitope
Sequence: YKLVVVGARGVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12R
Chemical type: Neo-epitope
Sequence: YKLVVVGARGVGKSALTIQLI
Assay category: TCell
Result: Positive-Low
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12R
Chemical type: Neo-epitope
Sequence: YKLVVVGARGVGKSALTIQLI
Assay category: TCell
Result: Positive-Low
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12R
Chemical type: Neo-epitope
Sequence: YKLVVVGARGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12R
Chemical type: Neo-epitope
Sequence: YKLVVVGARGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12R
Chemical type: Neo-epitope
Sequence: YKLVVVGARGVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G12R
Chemical type: Neo-epitope
Sequence: YKLVVVGARGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G12D
Chemical type: Neo-epitope
Sequence: YKLVVVGADGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12D
Chemical type: Neo-epitope
Sequence: YKLVVVGADGVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12D
Chemical type: Neo-epitope
Sequence: YKLVVVGADGVGKSALTIQLI
Assay category: TCell
Result: Positive-Low
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12D
Chemical type: Neo-epitope
Sequence: YKLVVVGADGVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12D
Chemical type: Neo-epitope
Sequence: YKLVVVGADGVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12D
Chemical type: Neo-epitope
Sequence: YKLVVVGADGVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12D
Chemical type: Neo-epitope
Sequence: YKLVVVGADGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G12D
Chemical type: Neo-epitope
Sequence: YKLVVVGADGVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G13D
Chemical type: Neo-epitope
Sequence: YKLVVVGAGDVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G13D
Chemical type: Neo-epitope
Sequence: YKLVVVGAGDVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G13D
Chemical type: Neo-epitope
Sequence: YKLVVVGAGDVGKSALTIQLI
Assay category: TCell
Result: Positive-Low
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G13D
Chemical type: Neo-epitope
Sequence: YKLVVVGAGDVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G13D
Chemical type: Neo-epitope
Sequence: YKLVVVGAGDVGKSALTIQLI
Assay category: TCell
Result: Positive-Low
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G13D
Chemical type: Neo-epitope
Sequence: YKLVVVGAGDVGKSALTIQLI
Assay category: TCell
Result: Positive-Low
Host:  42-76 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G13D
Chemical type: Neo-epitope
Sequence: YKLVVVGAGDVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G13D
Chemical type: Neo-epitope
Sequence: YKLVVVGAGDVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: KRAS G13D
Chemical type: Neo-epitope
Sequence: YKLVVVGAGDVGKSALTIQLI
Assay category: TCell
Result: Positive-Low
Host:  42-76 years
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G13D
Chemical type: Neo-epitope
Sequence: YKLVVVGAGDVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G13D
Chemical type: Neo-epitope
Sequence: YKLVVVGAGDVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G13D
Chemical type: Neo-epitope
Sequence: YKLVVVGAGDVGKSALTIQLI
Assay category: TCell
Result: Negative
Host:  42-76 years
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: KRAS G13D
Chemical type: Neo-epitope
Sequence: YKLVVVGAGDVGKSALTIQLI
Assay category: TCell
Result: Positive
Host:  42-76 years
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered