Reference: Caitlin I Stoddard; Jared Galloway; Helen Y Chu; Mackenzie M Shipley; Kevin Sung; Hannah L Itell; Caitlin R Wolf; Jennifer K Logue; Ariana Magedson; Meghan E Garrett; Katharine H D Crawford; Uri Laserson; Frederick A Matsen; Julie Overbaugh. "Epitope profiling reveals binding signatures of SARS-CoV-2 immune response in natural infection and cross-reactivity with endemic human CoVs." Cell reports (2021).

Epitope: CoV-2 S1,121-1,159a
Chemical type: Peptide from protein
Sequence: FVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNH
Position: 1121-1159
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 S1,121-1,159a
Chemical type: Peptide from protein
Sequence: FVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNH
Position: 1121-1159
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Negative

Epitope: CoV-2 S1,141-1,179a
Chemical type: Peptide from protein
Sequence: LQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNI
Position: 1141-1179
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 S1,141-1,179a
Chemical type: Peptide from protein
Sequence: LQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNI
Position: 1141-1179
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Negative

Epitope: CoV-2 S801-839a
Chemical type: Peptide from protein
Sequence: NFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGD
Position: 801-839
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 S801-839a
Chemical type: Peptide from protein
Sequence: NFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGD
Position: 801-839
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Negative

Epitope: CoV-2 S541-579
Chemical type: Peptide from protein
Sequence: FNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDP
Position: 541-579
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 S541-579
Chemical type: Peptide from protein
Sequence: FNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDP
Position: 541-579
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Negative

Epitope: CoV-2 S621-659
Chemical type: Peptide from protein
Sequence: PVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNS
Position: 621-659
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Negative

Epitope: CoV-2 S621-659
Chemical type: Peptide from protein
Sequence: PVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNS
Position: 621-659
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 S661-699
Chemical type: Peptide from protein
Sequence: ECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSL
Position: 661-699
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 S661-699
Chemical type: Peptide from protein
Sequence: ECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSL
Position: 661-699
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Negative

Epitope: CoV-2 S761-799
Chemical type: Peptide from protein
Sequence: TQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGG
Position: 761-799
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 S761-799
Chemical type: Peptide from protein
Sequence: TQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGG
Position: 761-799
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Negative

Epitope: CoV-2 S561-599
Chemical type: Peptide from protein
Sequence: PFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVIT
Position: 561-599
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 S561-599
Chemical type: Peptide from protein
Sequence: PFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVIT
Position: 561-599
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Negative

Epitope: CoV-2 S641-679
Chemical type: Peptide from protein
Sequence: NVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTN
Position: 641-679
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 S641-679
Chemical type: Peptide from protein
Sequence: NVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTN
Position: 641-679
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Negative

Epitope: CoV-2 S781-819
Chemical type: Peptide from protein
Sequence: VFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIE
Position: 781-819
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 S781-819
Chemical type: Peptide from protein
Sequence: VFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIE
Position: 781-819
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Negative

Epitope: CoV-2 S1,161-1,199
Chemical type: Peptide from protein
Sequence: SPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLID
Position: 1161-1199
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Negative

Epitope: CoV-2 S1,161-1,199
Chemical type: Peptide from protein
Sequence: SPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLID
Position: 1161-1199
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 S1,235-1,273
Chemical type: Peptide from protein
Sequence: CCMTSCCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT
Position: 1235-1273
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 S1,235-1,273
Chemical type: Peptide from protein
Sequence: CCMTSCCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT
Position: 1235-1273
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Negative

Epitope: CoV-2 S21-59b
Chemical type: Peptide from protein
Sequence: RTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFF
Position: 21-59
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 S21-59b
Chemical type: Peptide from protein
Sequence: RTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFF
Position: 21-59
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 S261-299
Chemical type: Peptide from protein
Sequence: GAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSET
Position: 261-299
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 S261-299
Chemical type: Peptide from protein
Sequence: GAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSET
Position: 261-299
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Negative

Epitope: CoV-2 S301-339
Chemical type: Peptide from protein
Sequence: CTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFG
Position: 301-339
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Negative

Epitope: CoV-2 S301-339
Chemical type: Peptide from protein
Sequence: CTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFG
Position: 301-339
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 N141-179
Chemical type: Peptide from protein
Sequence: TPKDHIGTRNPANNAAIVLQLPQGTTLPKGFYAEGSRGG
Position: 141-179
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Positive

Epitope: CoV-2 N141-179
Chemical type: Peptide from protein
Sequence: TPKDHIGTRNPANNAAIVLQLPQGTTLPKGFYAEGSRGG
Position: 141-179
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Negative

Epitope: CoV-2 N161-199
Chemical type: Peptide from protein
Sequence: LPQGTTLPKGFYAEGSRGGSQASSRSSSRSRNSSRNSTP
Position: 161-199
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Positive

Epitope: CoV-2 N161-199
Chemical type: Peptide from protein
Sequence: LPQGTTLPKGFYAEGSRGGSQASSRSSSRSRNSSRNSTP
Position: 161-199
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Negative

Epitope: CoV-2 N201-239
Chemical type: Peptide from protein
Sequence: SSRGTSPARMAGNGGDAALALLLLDRLNQLESKMSGKGQ
Position: 201-239
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Positive

Epitope: CoV-2 N201-239
Chemical type: Peptide from protein
Sequence: SSRGTSPARMAGNGGDAALALLLLDRLNQLESKMSGKGQ
Position: 201-239
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Negative

Epitope: CoV-2 N381-419
Chemical type: Peptide from protein
Sequence: ALPQRQKKQQTVTLLPAADLDDFSKQLQQSMSSADSTQA
Position: 381-419
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Negative

Epitope: CoV-2 N381-419
Chemical type: Peptide from protein
Sequence: ALPQRQKKQQTVTLLPAADLDDFSKQLQQSMSSADSTQA
Position: 381-419
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Positive

Epitope: CoV-2 N1-39b
Chemical type: Peptide from protein
Sequence: MSDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQ
Position: 1-39
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Positive

Epitope: CoV-2 N1-39b
Chemical type: Peptide from protein
Sequence: MSDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQ
Position: 1-39
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Positive

Epitope: CoV-2 N21-59
Chemical type: Peptide from protein
Sequence: SDSTGSNQNGERSGARSKQRRPQGLPNNTASWFTALTQH
Position: 21-59
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Positive

Epitope: CoV-2 N21-59
Chemical type: Peptide from protein
Sequence: SDSTGSNQNGERSGARSKQRRPQGLPNNTASWFTALTQH
Position: 21-59
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Negative

Epitope: CoV-2 N221-259
Chemical type: Peptide from protein
Sequence: LLLLDRLNQLESKMSGKGQQQQGQTVTKKSAAEASKKPR
Position: 221-259
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Positive

Epitope: CoV-2 N221-259
Chemical type: Peptide from protein
Sequence: LLLLDRLNQLESKMSGKGQQQQGQTVTKKSAAEASKKPR
Position: 221-259
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Negative

Epitope: CoV-2 N341-379
Chemical type: Peptide from protein
Sequence: DKDPNFKDQVILLNKHIDAYKTFPPTEPKKDKKKKADET
Position: 341-379
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Negative

Epitope: CoV-2 N341-379
Chemical type: Peptide from protein
Sequence: DKDPNFKDQVILLNKHIDAYKTFPPTEPKKDKKKKADET
Position: 341-379
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Positive

Epitope: CoV-2 N241-279a
Chemical type: Peptide from protein
Sequence: QQGQTVTKKSAAEASKKPRQKRTATKAYNVTQAFGRRGP
Position: 241-279
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Positive

Epitope: CoV-2 N241-279a
Chemical type: Peptide from protein
Sequence: QQGQTVTKKSAAEASKKPRQKRTATKAYNVTQAFGRRGP
Position: 241-279
Source molecule (GenBank): QHD43423.2
Assay category: BCell
Result: Negative

Epitope: CoV-2 ORF1ab1,961-1,999
Chemical type: Peptide from protein
Sequence: PDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATN
Position: 1961-1999
Source molecule (GenBank): QHD43415.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 ORF1ab1,961-1,999
Chemical type: Peptide from protein
Sequence: PDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATN
Position: 1961-1999
Source molecule (GenBank): QHD43415.1
Assay category: BCell
Result: Negative

Epitope: CoV-2 ORF1ab741-779
Chemical type: Peptide from protein
Sequence: FLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLV
Position: 741-779
Source molecule (GenBank): QHD43415.1
Assay category: BCell
Result: Negative

Epitope: CoV-2 ORF1ab741-779
Chemical type: Peptide from protein
Sequence: FLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLV
Position: 741-779
Source molecule (GenBank): QHD43415.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 ORF1ab4,481-4,519b
Chemical type: Peptide from protein
Sequence: LLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADL
Position: 4481-4519
Source molecule (GenBank): QHD43415.1
Assay category: BCell
Result: Positive

Epitope: CoV-2 ORF1ab4,481-4,519b
Chemical type: Peptide from protein
Sequence: LLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADL
Position: 4481-4519
Source molecule (GenBank): QHD43415.1
Assay category: BCell
Result: Positive