Reference: A E Herman; R M Tisch; S D Patel; S L Parry; J Olson; J A Noble; A P Cope; B Cox; M Congia; H O McDevitt2. "Determination of glutamic acid decarboxylase 65 peptides presented by the type I diabetes-associated HLA-DQ8 class II molecule identifies an immunogenic peptide motif." Journal of immunology (Baltimore, Md. : 1950) (1999).

Epitope: GAD 539-548
Chemical type: Peptide from protein
Sequence: EYGTTMVSYQ
Position: 539-548
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: GAD 104-112
Chemical type: Peptide from protein
Sequence: ERPTLAFLQ
Position: 104-112
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: GAD 127-136
Chemical type: Peptide from protein
Sequence: DRSTKVIDFH
Position: 127-136
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: GAD 208-217
Chemical type: Peptide from protein
Sequence: EIAPVFVLLE
Position: 208-217
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: GAD 536-550
Chemical type: Peptide from protein
Sequence: RMMEYGTTMVSYQPL
Position: 536-550
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
MHC allele types: 316 318 321 86
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GAD 536-550
Chemical type: Peptide from protein
Sequence: RMMEYGTTMVSYQPL
Position: 536-550
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
MHC allele types: 318 321 320 322 323 86
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GAD 101-115
Chemical type: Peptide from protein
Sequence: CDGERPTLAFLQDVM
Position: 101-115
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
MHC allele types: 318 321
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GAD 101-115
Chemical type: Peptide from protein
Sequence: CDGERPTLAFLQDVM
Position: 101-115
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
MHC allele types: 318 86
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GAD 126-140
Chemical type: Peptide from protein
Sequence: FDRSTKVIDFHYPNE
Position: 126-140
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
MHC allele types: 318 321 86
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GAD 126-140
Chemical type: Peptide from protein
Sequence: FDRSTKVIDFHYPNE
Position: 126-140
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
MHC allele types: 316 318 321
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GAD 206-220
Chemical type: Peptide from protein
Sequence: TYEIAPVFVLLEYVT
Position: 206-220
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
MHC allele types: 316 318 321 86
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GAD 206-220
Chemical type: Peptide from protein
Sequence: TYEIAPVFVLLEYVT
Position: 206-220
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
MHC allele types: 318 320 322 323 86 586
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GAD 461-475
Chemical type: Peptide from protein
Sequence: AKGTTGFEAHVDK
Position: 461-473
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
MHC allele types: 318 317 86
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GAD 461-475
Chemical type: Peptide from protein
Sequence: AKGTTGFEAHVDK
Position: 461-473
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
MHC allele types: 316 318 321 86 587
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo