Reference: Lennart M Roesner; Annice Heratizadeh; Susanne Wieschowski; Irene Mittermann; Rudolf Valenta; Britta Eiz-Vesper; Christian Hennig; Gesine Hansen; Christine S Falk; Thomas Werfel. "α-NAC-Specific Autoreactive CD8+ T Cells in Atopic Dermatitis Are of an Effector Memory Type and Secrete IL-4 and IFN-γ." Journal of immunology (Baltimore, Md. : 1950) (2016).

Epitope: alpha-NAC 1-9
Chemical type: Peptide from protein
Sequence: MPGEATETV
Position: 1-9
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 1-9
Chemical type: Peptide from protein
Sequence: MPGEATETV
Position: 1-9
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 1-9
Chemical type: Peptide from protein
Sequence: MPGEATETV
Position: 1-9
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: alpha-NAC 1-9
Chemical type: Peptide from protein
Sequence: MPGEATETV
Position: 1-9
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: alpha-NAC 1-9
Chemical type: Peptide from protein
Sequence: MPGEATETV
Position: 1-9
Source molecule (GenBank): NP_954984.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: alpha-NAC 182-190
Chemical type: Peptide from protein
Sequence: KLVMSQANV
Position: 182-190
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 182-190
Chemical type: Peptide from protein
Sequence: KLVMSQANV
Position: 182-190
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: alpha-NAC 182-190
Chemical type: Peptide from protein
Sequence: KLVMSQANV
Position: 182-190
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 182-190
Chemical type: Peptide from protein
Sequence: KLVMSQANV
Position: 182-190
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: alpha-NAC 182-190
Chemical type: Peptide from protein
Sequence: KLVMSQANV
Position: 182-190
Source molecule (GenBank): NP_954984.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 120.0

Epitope: alpha-NAC 12–20
Chemical type: Peptide from protein
Sequence: TEQELPQSQ
Position: 12-20
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 12–20
Chemical type: Peptide from protein
Sequence: TEQELPQSQ
Position: 12-20
Source molecule (GenBank): NP_954984.1
Assay category: MhcBinding
Result: Negative

Epitope: alpha-NAC 21–29
Chemical type: Peptide from protein
Sequence: AETGSGTAS
Position: 21-29
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 21–29
Chemical type: Peptide from protein
Sequence: AETGSGTAS
Position: 21-29
Source molecule (GenBank): NP_954984.1
Assay category: MhcBinding
Result: Negative

Epitope: alpha-NAC 32-40
Chemical type: Peptide from protein
Sequence: GESVPGIEE
Position: 32-40
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 32-40
Chemical type: Peptide from protein
Sequence: GESVPGIEE
Position: 32-40
Source molecule (GenBank): NP_954984.1
Assay category: MhcBinding
Result: Negative

Epitope: alpha-NAC 51-59
Chemical type: Peptide from protein
Sequence: AWLVAAAEI
Position: 51-59
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Positive
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 51-59
Chemical type: Peptide from protein
Sequence: AWLVAAAEI
Position: 51-59
Source molecule (GenBank): NP_954984.1
Assay category: MhcBinding
Result: Negative

Epitope: alpha-NAC 82-90
Chemical type: Peptide from protein
Sequence: KLGLLQVTG
Position: 82-90
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 92-100
Chemical type: Peptide from protein
Sequence: TRVTIWKSK
Position: 92-100
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 92-100
Chemical type: Peptide from protein
Sequence: TRVTIWKSK
Position: 92-100
Source molecule (GenBank): NP_954984.1
Assay category: MhcBinding
Result: Negative

Epitope: alpha-NAC 101-109
Chemical type: Peptide from protein
Sequence: NILFVITKL
Position: 101-109
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 101-109
Chemical type: Peptide from protein
Sequence: NILFVITKL
Position: 101-109
Source molecule (GenBank): NP_954984.1
Assay category: MhcBinding
Result: Negative

Epitope: alpha-NAC 112-120
Chemical type: Peptide from protein
Sequence: YKSPASDAY
Position: 112-120
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 112-120
Chemical type: Peptide from protein
Sequence: YKSPASDAY
Position: 112-120
Source molecule (GenBank): NP_954984.1
Assay category: MhcBinding
Result: Negative

Epitope: alpha-NAC 132-140
Chemical type: Peptide from protein
Sequence: SQQAQLAAA
Position: 132-140
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Positive
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 132-140
Chemical type: Peptide from protein
Sequence: SQQAQLAAA
Position: 132-140
Source molecule (GenBank): NP_954984.1
Assay category: MhcBinding
Result: Negative

Epitope: alpha-NAC 142-150
Chemical type: Peptide from protein
Sequence: KFRVQGEAV
Position: 142-150
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 172-180
Chemical type: Peptide from protein
Sequence: DETGVEVKD
Position: 172-180
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 172-180
Chemical type: Peptide from protein
Sequence: DETGVEVKD
Position: 172-180
Source molecule (GenBank): NP_954984.1
Assay category: MhcBinding
Result: Negative

Epitope: alpha-NAC 191-199
Chemical type: Peptide from protein
Sequence: SRAKAVRAL
Position: 191-199
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 192-200
Chemical type: Peptide from protein
Sequence: RAKAVRALK
Position: 192-200
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha-NAC 202-210
Chemical type: Peptide from protein
Sequence: NSNDIVNAI
Position: 202-210
Source molecule (GenBank): NP_954984.1
Assay category: TCell
Result: Negative
MHC allele types: 143
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo