Reference: Susumu Iiizumi; Junya Ohtake; Naoko Murakami; Taku Kouro; Mamoru Kawahara; Fumiko Isoda; Hiroshi Hamana; Hiroyuki Kishi; Norihiro Nakamura; Tetsuro Sasada. "Identification of Novel HLA Class II-Restricted Neoantigens Derived from Driver Mutations." Cancers (2019).

Epitope: KRAS-G12C
Chemical type: Peptide, no natural source
Sequence: MTEYKLVVVGACGVGKSALTIQLIQNH
Assay category: TCell
Result: Positive
MHC allele types: 143 215
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NRAS-Q61K
Chemical type: Peptide, no natural source
Sequence: GETCLLDILDTAGKEEYSAMRDQYMRT
Assay category: TCell
Result: Positive-Low
MHC allele types: 143 215
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PIK3CA-H1047R
Chemical type: Peptide, no natural source
Sequence: EALEYFMKQMNDARHGGWTTKMDWIFH
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KRAS-G12V
Chemical type: Peptide, no natural source
Sequence: MTEYKLVVVGAVGVGKSALTIQLIQNH
Assay category: TCell
Result: Negative
MHC allele types: 143 215
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NRAS-Q61R
Chemical type: Peptide, no natural source
Sequence: GETCLLDILDTAGREEYSAMRDQYMRT
Assay category: TCell
Result: Positive
MHC allele types: 143 215
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PIK3CA-E545K
Chemical type: Peptide, no natural source
Sequence: KAISTRDPLSEITKQEKDFLWSHRHYC
Assay category: TCell
Result: Negative
MHC allele types: 143 215
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KRAS-G12D
Chemical type: Peptide, no natural source
Sequence: MTEYKLVVVGADGVGKSALTIQLIQNH
Assay category: TCell
Result: Positive-Low
MHC allele types: 143 215
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KRAS-G12R
Chemical type: Peptide, no natural source
Sequence: MTEYKLVVVGARGVGKSALTIQLIQNH
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: KRAS-G13D
Chemical type: Peptide, no natural source
Sequence: MTEYKLVVVGAGDVGKSALTIQLIQNH
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C-Kit-D816V
Chemical type: Peptide, no natural source
Sequence: GRITKICDFGLARVIKNDSNYVVKGNA
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C-Kit-D816V
Chemical type: Peptide, no natural source
Sequence: GRITKICDFGLARVIKNDSNYVVKGNA
Assay category: TCell
Result: Positive-Low
MHC allele types: 143 215
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LEYFMKQMNDARHGG
Chemical type: Peptide, no natural source
Sequence: LEYFMKQMNDARHGG
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MNDARHGGWTTKMDW
Chemical type: Peptide, no natural source
Sequence: MNDARHGGWTTKMDW
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GLARVIKNDSNYVVK
Chemical type: Peptide, no natural source
Sequence: GLARVIKNDSNYVVK
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone