Reference: Eva Johansson; Xiaoai Wu; Bingke Yu; Zhiru Yang; Zheng Cao; Charlotte Wiberg; Claus B Jeppesen; Fritz Poulsen. "Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties." Protein science : a publication of the Protein Society (2021).

Epitope: Epitope of HUI-018 Fab on human Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: I: C95, C96, T97, I99, C100, S101, L102, Y103, E106; J: H29, L30, H34, A38, L41
Source molecule (GenBank): P01308.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00060

Epitope: Epitope of HUI-018 Fab on human Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: I: C95, C96, T97, I99, C100, S101, L102, Y103, E106; J: H29, L30, H34, A38, L41
Source molecule (GenBank): P01308.1
Assay category: BCell
Result: Positive

Epitope: Epitope of HUI-018 Fab on human Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: I: C95, C96, T97, I99, C100, S101, L102, Y103, E106; J: H29, L30, H34, A38, L41
Source molecule (GenBank): P01308.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010

Epitope: Epitope of HUI-018 Fab on human Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: I: C95, C96, T97, I99, C100, S101, L102, Y103, E106; J: H29, L30, H34, A38, L41
Source molecule (GenBank): P01308.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.0

Epitope: Epitope of HUI-018 Fab on human Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: I: C95, C96, T97, I99, C100, S101, L102, Y103, E106; J: H29, L30, H34, A38, L41
Source molecule (GenBank): P01308.1
Assay category: BCell
Result: Positive
Quantitative measurement: 200000.0

Epitope: Epitope of HUI-018 Fab on human Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: I: C95, C96, T97, I99, C100, S101, L102, Y103, E106; J: H29, L30, H34, A38, L41
Source molecule (GenBank): P01308.1
Assay category: BCell
Result: Positive
Quantitative measurement: 300000.0

Epitope: Epitope of HUI-018 Fab on human Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: I: C95, C96, T97, I99, C100, S101, L102, Y103, E106; J: H29, L30, H34, A38, L41
Source molecule (GenBank): P01308.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.42

Epitope: Epitope of HUI-018 Fab on human Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: I: C95, C96, T97, I99, C100, S101, L102, Y103, E106; J: H29, L30, H34, A38, L41
Source molecule (GenBank): P01308.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.0

Epitope: Epitope of OXI-005 Fab on human Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G64, V66, E67, Y108, C109, N110; H: F49, Y50, T51, P52, K53, T54
Source molecule (GenBank): P01308.1
Assay category: BCell
Result: Positive
Quantitative measurement: 20.0

Epitope: Epitope of OXI-005 Fab on human Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G64, V66, E67, Y108, C109, N110; H: F49, Y50, T51, P52, K53, T54
Source molecule (GenBank): P01308.1
Assay category: BCell
Result: Positive
Quantitative measurement: 30000.0

Epitope: Epitope of OXI-005 Fab on human Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G64, V66, E67, Y108, C109, N110; H: F49, Y50, T51, P52, K53, T54
Source molecule (GenBank): P01308.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00060

Epitope: Epitope of OXI-005 Fab on human Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G64, V66, E67, Y108, C109, N110; H: F49, Y50, T51, P52, K53, T54
Source molecule (GenBank): P01308.1
Assay category: BCell
Result: Positive
Quantitative measurement: 40000.0

Epitope: Epitope of OXI-005 Fab on human Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G64, V66, E67, Y108, C109, N110; H: F49, Y50, T51, P52, K53, T54
Source molecule (GenBank): P01308.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0020

Epitope: Epitope of OXI-005 Fab on human Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G64, V66, E67, Y108, C109, N110; H: F49, Y50, T51, P52, K53, T54
Source molecule (GenBank): P01308.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.2

Epitope: Epitope of OXI-005 Fab on human Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G64, V66, E67, Y108, C109, N110; H: F49, Y50, T51, P52, K53, T54
Source molecule (GenBank): P01308.1
Assay category: BCell
Result: Positive
Quantitative measurement: 50.0

Epitope: Epitope of OXI-005 Fab on human Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G64, V66, E67, Y108, C109, N110; H: F49, Y50, T51, P52, K53, T54
Source molecule (GenBank): P01308.1
Assay category: BCell
Result: Positive

Epitope: Epitope of OXI-005 Fab on porcine Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G64, V66, E67, N105, Y106, C107, N108; H: F49, Y50, T51, P52, K53, A54
Source molecule (GenBank): NP_001103242.1
Assay category: BCell
Result: Positive
Quantitative measurement: 50.0

Epitope: Epitope of OXI-005 Fab on porcine Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G64, V66, E67, N105, Y106, C107, N108; H: F49, Y50, T51, P52, K53, A54
Source molecule (GenBank): NP_001103242.1
Assay category: BCell
Result: Positive
Quantitative measurement: 40000.0

Epitope: Epitope of OXI-005 Fab on porcine Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G64, V66, E67, N105, Y106, C107, N108; H: F49, Y50, T51, P52, K53, A54
Source molecule (GenBank): NP_001103242.1
Assay category: BCell
Result: Positive
Quantitative measurement: 30000.0

Epitope: Epitope of OXI-005 Fab on porcine Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G64, V66, E67, N105, Y106, C107, N108; H: F49, Y50, T51, P52, K53, A54
Source molecule (GenBank): NP_001103242.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00060

Epitope: Epitope of OXI-005 Fab on porcine Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G64, V66, E67, N105, Y106, C107, N108; H: F49, Y50, T51, P52, K53, A54
Source molecule (GenBank): NP_001103242.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.4

Epitope: Epitope of OXI-005 Fab on porcine Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G64, V66, E67, N105, Y106, C107, N108; H: F49, Y50, T51, P52, K53, A54
Source molecule (GenBank): NP_001103242.1
Assay category: BCell
Result: Positive
Quantitative measurement: 20.0

Epitope: Epitope of OXI-005 Fab on porcine Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G64, V66, E67, N105, Y106, C107, N108; H: F49, Y50, T51, P52, K53, A54
Source molecule (GenBank): NP_001103242.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0020

Epitope: Epitope of OXI-005 Fab on porcine Insulin
Chemical type: Region on multi-chain protein
Discontinuous residues: G: G64, V66, E67, N105, Y106, C107, N108; H: F49, Y50, T51, P52, K53, A54
Source molecule (GenBank): NP_001103242.1
Assay category: BCell
Result: Positive