Reference: Nicole H Kattah; Evan W Newell; Justin Ansel Jarrell; Alvina D Chu; Jianming Xie; Michael G Kattah; Ofir Goldberger; Jessica Ye; Eliza F Chakravarty; Mark M Davis; Paul J Utz. "Tetramers reveal IL-17-secreting CD4+ T cells that are specific for U1-70 in lupus and mixed connective tissue disease." Proceedings of the National Academy of Sciences of the United States of America (2015).

Epitope: U1-70 131-150 mouse
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIE
Position: 131-150
Source molecule (GenBank): NP_033250.3
Assay category: TCell
Result: Positive-Low
Host:  13-31 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: U1-70 131-150 mouse
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIE
Position: 131-150
Source molecule (GenBank): NP_033250.3
Assay category: TCell
Result: Negative
Host:  6-27 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: U1-70 131-150 mouse
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIE
Position: 131-150
Source molecule (GenBank): NP_033250.3
Assay category: MhcBinding
Result: Positive

Epitope: U1-70 131-150 human
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIE
Position: 131-150
Source molecule (GenBank): AAA03001.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: U1-70 131-150 human
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIE
Position: 131-150
Source molecule (GenBank): AAA03001.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: U1-70 131-150 human
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIE
Position: 131-150
Source molecule (GenBank): AAA03001.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: U1-70 131-150 human
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIE
Position: 131-150
Source molecule (GenBank): AAA03001.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: U1-70 131-150 human
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIE
Position: 131-150
Source molecule (GenBank): AAA03001.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: U1-70 131-150 human
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIE
Position: 131-150
Source molecule (GenBank): AAA03001.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: U1-70 131-150 human
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIE
Position: 131-150
Source molecule (GenBank): AAA03001.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: U1-70 131-150 (P140)
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIE
Position: 131-150
Source molecule (GenBank): NP_033250.3
Assay category: TCell
Result: Positive-Low
Host:  13-31 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: U1-70 131-150 (P140)
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIE
Position: 131-150
Source molecule (GenBank): NP_033250.3
Assay category: TCell
Result: Positive-Low
Host:  6-27 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: U1-70 131-150 (P140)
Chemical type: Peptide from protein
Sequence: RIHMVYSKRSGKPRGYAFIE
Position: 131-150
Source molecule (GenBank): NP_033250.3
Assay category: MhcBinding
Result: Positive

Epitope: B2M 42-59
Chemical type: Peptide from protein
Sequence: HPPHIEIQMLKNGKKIPK
Position: 51-68
Source molecule (GenBank): P01887.1
Assay category: MhcBinding
Result: Positive

Epitope: MCC 88-103
Chemical type: Peptide from protein
Sequence: ANERADLIAYLKQATK
Position: 93-108
Source molecule (GenBank): P00039.2
Assay category: MhcBinding
Result: Positive