LiteFold/IEDB huggingface dataset:
Reference: S Hawke; H Matsuo; M Nicolle; P Wordsworth; L Corlett; E Spack; S Deshpande; P C Driscoll; N Willcox. "Cross-restriction of a T cell clone to HLA-DR alleles associated with rheumatoid arthritis: clues to arthritogenic peptide motifs." Arthritis and rheumatism (1999).

Epitope: hAChRα75-115
Chemical type: Peptide from protein
Sequence: VKKIHIPSEKIWRPDLVLYNNADGDFAIVKFTKVLLQYTGH
Position: 120-160
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα138-167
Chemical type: Peptide from protein
Sequence: DEQNCSMKLGTWTYDGSVVAINPESDQPDL
Position: 183-212
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα144-163
Chemical type: Peptide from protein
Sequence: MKLGTWTYDGSVVAINPESD
Position: 189-208
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα144-163
Chemical type: Peptide from protein
Sequence: MKLGTWTYDGSVVAINPESD
Position: 189-208
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα144-163
Chemical type: Peptide from protein
Sequence: MKLGTWTYDGSVVAINPESD
Position: 189-208
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone
Reference: S J Tzartos; M Remoundos. "Detection of antibodies directed against the cytoplasmic region of the human acetylcholine receptor in sera from myasthenia gravis patients." Clinical and experimental immunology (1999).

Epitope: VICE-beta
Chemical type: Peptide from protein
Sequence: EYFIRK
Position: 378-383
Source molecule (GenBank): P02712.1
Assay category: BCell
Result: Positive

Epitope: VICE-beta
Chemical type: Peptide from protein
Sequence: EYFIRK
Position: 378-383
Source molecule (GenBank): P02712.1
Assay category: BCell
Result: Positive

Epitope: VICE-alpha
Chemical type: Peptide from protein
Sequence: KSAIEGVK
Position: 397-404
Source molecule (GenBank): P02710.1
Assay category: BCell
Result: Positive

Epitope: VICE-alpha
Chemical type: Peptide from protein
Sequence: KSAIEGVK
Position: 397-404
Source molecule (GenBank): P02710.1
Assay category: BCell
Result: Positive
Reference: H B Wang; H Li; B He; M Bakheit; M Levi; B Wahren; A Berglöf; K Sandstedt; H Link; F D Shi. "The role of B-cells in experimental myasthenia gravis in mice." Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie (1999).

Epitope: AChR α146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: mononuclear cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: AChR α146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: mononuclear cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo
Reference: N Nagvekar; L Corlett; L W Jacobson; H Matsuo; R Chalkley; P C Driscoll; S Deshpande; E G Spack; N Willcox. "Scanning a DRB3*0101 (DR52a)-restricted epitope cross-presented by DR3: overlapping natural and artificial determinants in the human acetylcholine receptor." Journal of immunology (Baltimore, Md. : 1950) (1999).

Epitope: α148-157
Chemical type: Peptide from protein
Sequence: TWTYDGSVVA
Position: 193-202
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  15 years
Cell type: T cell
Tissue: thymus
Culture conditions: Cell Line / Clone

Epitope: α148-157
Chemical type: Peptide from protein
Sequence: TWTYDGSVVA
Position: 193-202
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  15 years
Cell type: T cell
Tissue: thymus
Culture conditions: Cell Line / Clone

Epitope: α148-157
Chemical type: Peptide from protein
Sequence: TWTYDGSVVA
Position: 193-202
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  15 years
Cell type: T cell
Tissue: thymus
Culture conditions: Cell Line / Clone

Epitope: α147-157
Chemical type: Peptide from protein
Sequence: GTWTYDGSVVA
Position: 192-202
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  17 years
Cell type: T cell
Tissue: thymus
Culture conditions: Cell Line / Clone

Epitope: α147-157
Chemical type: Peptide from protein
Sequence: GTWTYDGSVVA
Position: 192-202
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  17 years
Cell type: T cell
Tissue: thymus
Culture conditions: Cell Line / Clone

Epitope: α147-157
Chemical type: Peptide from protein
Sequence: GTWTYDGSVVA
Position: 192-202
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  17 years
Cell type: T cell
Tissue: thymus
Culture conditions: Cell Line / Clone
Reference: B Yang; K R McIntosh; D B Drachman. "How subtle differences in MHC class II affect the severity of experimental myasthenia gravis." Clinical immunology and immunopathology (1998).

Epitope: Tα111-126
Chemical type: Peptide from protein
Sequence: DYTGKIMWTPPAIFKS
Position: 135-150
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: Tα111-126
Chemical type: Peptide from protein
Sequence: DYTGKIMWTPPAIFKS
Position: 135-150
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: Tα111-126
Chemical type: Peptide from protein
Sequence: DYTGKIMWTPPAIFKS
Position: 135-150
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: Tα146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: Tα360-378
Chemical type: Peptide from protein
Sequence: VIFQTPLIKNPDVKSAIEG
Position: 384-402
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: Tα360-378
Chemical type: Peptide from protein
Sequence: VIFQTPLIKNPDVKSAIEG
Position: 384-402
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone
Reference: V Dedhia; E Goluszko; B Wu; C Deng; P Christadoss. "The effect of B cell deficiency on the immune response to acetylcholine receptor and the development of experimental autoimmune myasthenia gravis." Clinical immunology and immunopathology (1998).

Epitope: AchR α146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): AAA96705.1
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: AchR α146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): AAA96705.1
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: AchR α146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): AAA96705.1
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo
Reference: S L Kirshner; A Waisman; E Zisman; A Ben-Nun; E Mozes. "T cell receptor expression and differential proliferative responses by T cells specific to a myasthenogenic peptide." Cellular immunology (1997).

Epitope: Human AChR p195-212
Chemical type: Peptide from protein
Sequence: DTPYLDITYHFVMQRLPL
Position: 240-257
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: lymph node
Culture conditions: Cell Line / Clone
Reference: H Yoshikawa; E H Lambert; D R Walser-Kuntz; Y Yasukawa; D J McCormick; V A Lennon. "A 17-Mer self-peptide of acetylcholine receptor binds to B cell MHC class II, activates helper T cells, and stimulates autoantibody production and electrophysiologic signs of myasthenia gravis." Journal of immunology (Baltimore, Md. : 1950) (1997).

Epitope: Hα121-136
Chemical type: Peptide from protein
Sequence: PAIFKSYCEIIVTHFP
Position: 141-156
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Host: F 10-14 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Hα125-147
Chemical type: Peptide from protein
Sequence: KSYCEIIVTHFPFDEQNCSMKLG
Position: 145-167
Source molecule (GenBank): AAD14247.1
Assay category: BCell
Result: Positive
Host: F 10-14 weeks

Epitope: Hα125-147
Chemical type: Peptide from protein
Sequence: KSYCEIIVTHFPFDEQNCSMKLG
Position: 145-167
Source molecule (GenBank): AAD14247.1
Assay category: BCell
Result: Positive
Host: F 10-14 weeks

Epitope: Hα125-147
Chemical type: Peptide from protein
Sequence: KSYCEIIVTHFPFDEQNCSMKLG
Position: 145-167
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Host: F 10-14 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Hα125-147
Chemical type: Peptide from protein
Sequence: KSYCEIIVTHFPFDEQNCSMKLG
Position: 145-167
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Host: F 10-14 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Tα125-147
Chemical type: Peptide from protein
Sequence: KSYCEIIVTHFPFDQQNCTMKLG
Position: 149-171
Source molecule (GenBank): AAA96705.1
Assay category: TCell
Result: Positive
Host: F 10-14 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Tα125-147
Chemical type: Peptide from protein
Sequence: KSYCEIIVTHFPFDQQNCTMKLG
Position: 149-171
Source molecule (GenBank): AAA96705.1
Assay category: TCell
Result: Positive
Host: F 10-14 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Hα131-147
Chemical type: Peptide from protein
Sequence: IVTHFPFDEQNCSMKLG
Position: 151-167
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Host: F 10-14 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Hα137-147
Chemical type: Peptide from protein
Sequence: FDEQNCSMKLG
Position: 157-167
Source molecule (GenBank): AAD14247.1
Assay category: BCell
Result: Negative
Host: F 10-14 weeks

Epitope: Hα137-147
Chemical type: Peptide from protein
Sequence: FDEQNCSMKLG
Position: 157-167
Source molecule (GenBank): AAD14247.1
Assay category: BCell
Result: Positive-Low
Host: F 10-14 weeks
Reference: T Kanai; Y Nomura; M Segawa; K Takagi; S Senju; S Matsushita; Y Nishimura. "Immuno-suppressive peptides for a human T cell clone autoreactive to a unique acetylcholine receptor alpha subunit peptide presented by the disease-susceptible HLA-DQ6 in infant-onset myasthenia gravis." Human immunology (1997).

Epitope: AChRα p75-87
Chemical type: Peptide from protein
Sequence: PLFSHLQNEQWVD
Position: 95-107
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
MHC allele types: 92 89 353 333
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: AChRα p75-87
Chemical type: Peptide from protein
Sequence: PLFSHLQNEQWVD
Position: 95-107
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive-High
MHC allele types: 92 89 353 333
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: AChRα p75-87
Chemical type: Peptide from protein
Sequence: PLFSHLQNEQWVD
Position: 95-107
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
MHC allele types: 92 89 353 333
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: AChRα p75-87
Chemical type: Peptide from protein
Sequence: PLFSHLQNEQWVD
Position: 95-107
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
MHC allele types: 92 89 353 333
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: AChRα p75-87
Chemical type: Peptide from protein
Sequence: PLFSHLQNEQWVD
Position: 95-107
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive-Low
MHC allele types: 92 89 353 333
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone
Reference: M Takamori; K Iwasa; K Komai. "Antibodies to synthetic peptides of the alpha1A subunit of the voltage-gated calcium channel in Lambert-Eaton myasthenic syndrome." Neurology (1997).

Epitope: Domain I S5-S6 linker peptide
Chemical type: Peptide from protein
Sequence: MGKFHTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTRCQPYWEGPNNGI
Position: 249-298
Source molecule (GenBank): CAA40871.1
Assay category: BCell
Result: Negative

Epitope: Domain I S5-S6 linker peptide
Chemical type: Peptide from protein
Sequence: MGKFHTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTRCQPYWEGPNNGI
Position: 249-298
Source molecule (GenBank): CAA40871.1
Assay category: BCell
Result: Negative

Epitope: Domain I S5-S6 linker peptide
Chemical type: Peptide from protein
Sequence: MGKFHTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTRCQPYWEGPNNGI
Position: 249-298
Source molecule (GenBank): CAA40871.1
Assay category: BCell
Result: Negative

Epitope: Domain II S5-S6 linker peptide
Chemical type: Peptide from protein
Sequence: GGQFNFDEGTPPTNFDTFPAA
Position: 637-657
Source molecule (GenBank): CAA40871.1
Assay category: BCell
Result: Positive

Epitope: Domain II S5-S6 linker peptide
Chemical type: Peptide from protein
Sequence: GGQFNFDEGTPPTNFDTFPAA
Position: 637-657
Source molecule (GenBank): CAA40871.1
Assay category: BCell
Result: Negative

Epitope: Domain II S5-S6 linker peptide
Chemical type: Peptide from protein
Sequence: GGQFNFDEGTPPTNFDTFPAA
Position: 637-657
Source molecule (GenBank): CAA40871.1
Assay category: BCell
Result: Negative

Epitope: Domain III S5-S6 linker peptide
Chemical type: Peptide from protein
Sequence: KGKFFHCTDESKEFEKDCRGKYLLYEKNEVK
Position: 1409-1439
Source molecule (GenBank): CAA40871.1
Assay category: BCell
Result: Negative

Epitope: Domain III S5-S6 linker peptide
Chemical type: Peptide from protein
Sequence: KGKFFHCTDESKEFEKDCRGKYLLYEKNEVK
Position: 1409-1439
Source molecule (GenBank): CAA40871.1
Assay category: BCell
Result: Negative

Epitope: Domain III S5-S6 linker peptide
Chemical type: Peptide from protein
Sequence: KGKFFHCTDESKEFEKDCRGKYLLYEKNEVK
Position: 1409-1439
Source molecule (GenBank): CAA40871.1
Assay category: BCell
Result: Negative
Reference: Y Katz-Levy; M Paas-Rozner; S Kirshner; M Dayan; E Zisman; M Fridkin; I Wirguin; M Sela; E Mozes. "A peptide composed of tandem analogs of two myasthenogenic T cell epitopes interferes with specific autoimmune responses." Proceedings of the National Academy of Sciences of the United States of America (1997).

Epitope: AChR peptide p195-212
Chemical type: Peptide from protein
Sequence: DTPYLDITYHFVMQRLPL
Position: 240-257
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: AChR peptide p195-212
Chemical type: Peptide from protein
Sequence: DTPYLDITYHFVMQRLPL
Position: 240-257
Source molecule (GenBank): P02708.2
Assay category: MhcBinding
Result: Positive

Epitope: AChR peptide p259-271
Chemical type: Peptide from protein
Sequence: VIVELIPSTSSAV
Position: 304-316
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: AChR peptide p259-271
Chemical type: Peptide from protein
Sequence: VIVELIPSTSSAV
Position: 304-316
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: AChR peptide p259-271
Chemical type: Peptide from protein
Sequence: VIVELIPSTSSAV
Position: 304-316
Source molecule (GenBank): P02708.2
Assay category: MhcBinding
Result: Negative

Epitope: AChR peptide p259-271
Chemical type: Peptide from protein
Sequence: VIVELIPSTSSAV
Position: 304-316
Source molecule (GenBank): P02708.2
Assay category: MhcBinding
Result: Positive

Epitope: AChR analog Lys-262–Ala-207
Chemical type: Peptide, no natural source
Sequence: VIVKLIPSTSSAVDTPYLDITYHFVAQRLPL
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: AChR analog Lys-262–Ala-207
Chemical type: Peptide, no natural source
Sequence: VIVKLIPSTSSAVDTPYLDITYHFVAQRLPL
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: AChR analog Lys-262–Ala-207
Chemical type: Peptide, no natural source
Sequence: VIVKLIPSTSSAVDTPYLDITYHFVAQRLPL
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: AChR analog Lys-262–Ala-207
Chemical type: Peptide, no natural source
Sequence: VIVKLIPSTSSAVDTPYLDITYHFVAQRLPL
Assay category: MhcBinding
Result: Positive

Epitope: AChR analog Lys-262–Ala-207
Chemical type: Peptide, no natural source
Sequence: VIVKLIPSTSSAVDTPYLDITYHFVAQRLPL
Assay category: MhcBinding
Result: Positive

Epitope: Ala-207-Lys-262
Chemical type: Peptide, no natural source
Sequence: DTPYLDITYHFVAQRLPLVIVKLIPSTSSAV
Assay category: MhcBinding
Result: Positive

Epitope: Ala-207-Lys-262
Chemical type: Peptide, no natural source
Sequence: DTPYLDITYHFVAQRLPLVIVKLIPSTSSAV
Assay category: MhcBinding
Result: Positive
Reference: J S Rosenberg; M Oshima; M Z Atassi. "B-cell activation in vitro by helper T cells specific to region alpha 146-162 of Torpedo californica nicotinic acetylcholine receptor." Journal of immunology (Baltimore, Md. : 1950) (1996).

Epitope: tAChR 146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): P02710.1
Assay category: BCell
Result: Positive-Low
Host: F 8-10 weeks

Epitope: tAChR 146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: tAChR 146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: tAChR 146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: tAChR 146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: tAChR 45-60
Chemical type: Peptide from protein
Sequence: EVNQIVETNVRLRQQW
Position: 69-84
Source molecule (GenBank): P02710.1
Assay category: BCell
Result: Positive
Host: F 8-10 weeks

Epitope: tAChR 56-71
Chemical type: Peptide from protein
Sequence: LRQQWIDVRLRWNPAD
Position: 80-95
Source molecule (GenBank): P02710.1
Assay category: BCell
Result: Positive
Host: F 8-10 weeks

Epitope: tAChR 122-138
Chemical type: Peptide from protein
Sequence: AIFKSYCEIIVTHFPFD
Position: 146-162
Source molecule (GenBank): P02710.1
Assay category: BCell
Result: Positive
Host: F 8-10 weeks

Epitope: tAChR 134-150
Chemical type: Peptide from protein
Sequence: HFPFDQQNCTMKLGIWT
Position: 158-174
Source molecule (GenBank): P02710.1
Assay category: BCell
Result: Positive
Host: F 8-10 weeks

Epitope: tAChR 170-186
Chemical type: Peptide from protein
Sequence: FMESGEWVMKDYRGWKH
Position: 194-210
Source molecule (GenBank): P02710.1
Assay category: BCell
Result: Positive
Host: F 8-10 weeks

Epitope: tAChR 182-198
Chemical type: Peptide from protein
Sequence: RGWKHWVYYTCCPDTPY
Position: 206-222
Source molecule (GenBank): P02710.1
Assay category: BCell
Result: Negative
Host: F 8-10 weeks
Reference: S Araga; F S Galin; M Kishimoto; A Adachi; J B Blalock. "Prevention of experimental autoimmune myasthenia gravis by a monoclonal antibody to a complementary peptide for the main immunogenic region of the acetylcholine receptors." Journal of immunology (Baltimore, Md. : 1950) (1996).

Epitope: RhCA 67-16
Chemical type: Peptide, no natural source
Sequence: NIHPKAPIWGIITSNF
Assay category: BCell
Result: Positive

Epitope: RhCA 67-16
Chemical type: Peptide, no natural source
Sequence: NIHPKAPIWGIITSNF
Assay category: BCell
Result: Positive

Epitope: RhCA 67-16
Chemical type: Peptide, no natural source
Sequence: NIHPKAPIWGIITSNF
Assay category: BCell
Result: Positive
Reference: E Zisman; Y Katz-Levy; M Dayan; S L Kirshner; M Paas-Rozner; A Karni; O Abramsky; C Brautbar; M Fridkin; M Sela; E Mozes. "Peptide analogs to pathogenic epitopes of the human acetylcholine receptor alpha subunit as potential modulators of myasthenia gravis." Proceedings of the National Academy of Sciences of the United States of America (1996).

Epitope: hAChR alpha (195-212)
Chemical type: Peptide from protein
Sequence: DTPYLDITYHFVMQRLPL
Position: 240-257
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  21-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: hAChR alpha (259-271)
Chemical type: Peptide from protein
Sequence: VIVELIPSTSSAV
Position: 304-316
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  21-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: M L Fu; W Schulze; G Wallukat; A Hjalmarson; J Hoebeke. "A synthetic peptide corresponding to the second extracellular loop of the human M2 acetylcholine receptor induces pharmacological and morphological changes in cardiomyocytes by active immunization after 6 months in rabbits." Clinical immunology and immunopathology (1996).

Epitope: human M2 acetylcholine receptor (169-193)
Chemical type: Peptide from protein
Sequence: VRTVEDGECYIQFFSNAAVTFGTAI
Position: 142-166
Source molecule (GenBank): BAA94476.1
Assay category: TCell
Result: Positive