Reference: Dhiraj Mannar; James W Saville; Zehua Sun; Xing Zhu; Michelle M Marti; Shanti S Srivastava; Alison M Berezuk; Steven Zhou; Katharine S Tuttle; Michele D Sobolewski; Andrew Kim; Benjamin R Treat; Priscila Mayrelle Da Silva Castanha; Jana L Jacobs; Simon M Barratt-Boyes; John W Mellors; Dimiter S Dimitrov; Wei Li; Sriram Subramaniam. "SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization." Nature communications (2022).

Epitope: Epitope of 4-8 Fab on SARS-CoV-2 Gamma S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q14, Y144, Y145, H146, K147, E154, S155, E156, R158, R246, S247, Y248, L249, T250, P251, G252, D253, S254, W258
Source molecule (GenBank): QWE88956.1
Assay category: BCell
Result: Positive
Host:  50-71 years

Epitope: Epitope of 4-8 Fab on SARS-CoV-2 Gamma S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q14, Y144, Y145, H146, K147, E154, S155, E156, R158, R246, S247, Y248, L249, T250, P251, G252, D253, S254, W258
Source molecule (GenBank): QWE88956.1
Assay category: BCell
Result: Positive
Host:  50-71 years

Epitope: Epitope of 4-8 Fab on SARS-CoV-2 Gamma S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q14, Y144, Y145, H146, K147, E154, S155, E156, R158, R246, S247, Y248, L249, T250, P251, G252, D253, S254, W258
Source molecule (GenBank): QWE88956.1
Assay category: BCell
Result: Positive
Host:  50-71 years

Epitope: Epitope of 4-8 Fab on SARS-CoV-2 Gamma S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q14, Y144, Y145, H146, K147, E154, S155, E156, R158, R246, S247, Y248, L249, T250, P251, G252, D253, S254, W258
Source molecule (GenBank): QWE88956.1
Assay category: BCell
Result: Positive
Host:  50-71 years

Epitope: Epitope of 4-8 Fab on SARS-CoV-2 Gamma S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q14, Y144, Y145, H146, K147, E154, S155, E156, R158, R246, S247, Y248, L249, T250, P251, G252, D253, S254, W258
Source molecule (GenBank): QWE88956.1
Assay category: BCell
Result: Positive
Host:  50-71 years

Epitope: Epitope of 4A8 Fab on SARS-CoV-2 Gamma S
Chemical type: Discontinuous protein residues
Discontinuous residues: V143, Y144, Y145, H146, K147, N148, K150, W152, H245, R246, S247, Y248
Source molecule (GenBank): QWE88956.1
Assay category: BCell
Result: Positive
Host:  28-53 years

Epitope: Epitope of 4A8 Fab on SARS-CoV-2 Gamma S
Chemical type: Discontinuous protein residues
Discontinuous residues: V143, Y144, Y145, H146, K147, N148, K150, W152, H245, R246, S247, Y248
Source molecule (GenBank): QWE88956.1
Assay category: BCell
Result: Positive
Host:  28-53 years

Epitope: Epitope of 4A8 Fab on SARS-CoV-2 Gamma S
Chemical type: Discontinuous protein residues
Discontinuous residues: V143, Y144, Y145, H146, K147, N148, K150, W152, H245, R246, S247, Y248
Source molecule (GenBank): QWE88956.1
Assay category: BCell
Result: Positive
Host:  28-53 years

Epitope: Epitope of 4A8 Fab on SARS-CoV-2 Gamma S
Chemical type: Discontinuous protein residues
Discontinuous residues: V143, Y144, Y145, H146, K147, N148, K150, W152, H245, R246, S247, Y248
Source molecule (GenBank): QWE88956.1
Assay category: BCell
Result: Positive
Host:  28-53 years

Epitope: Epitope of 4A8 Fab on SARS-CoV-2 Gamma S
Chemical type: Discontinuous protein residues
Discontinuous residues: V143, Y144, Y145, H146, K147, N148, K150, W152, H245, R246, S247, Y248
Source molecule (GenBank): QWE88956.1
Assay category: BCell
Result: Positive
Host:  28-53 years

Epitope: Epitope of S2M11 Fab on SARS-CoV-2 Epsilon S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, R452, L455, F456, E484, G485, F486, Y489, F490, L492, Q493, S494, G496; B: F342, N343, T345, V367, L368, S371, A372, S373, F374, W436, N440, L441
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of S2M11 Fab on SARS-CoV-2 Epsilon S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, R452, L455, F456, E484, G485, F486, Y489, F490, L492, Q493, S494, G496; B: F342, N343, T345, V367, L368, S371, A372, S373, F374, W436, N440, L441
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of S2M11 Fab on SARS-CoV-2 Epsilon S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, R452, L455, F456, E484, G485, F486, Y489, F490, L492, Q493, S494, G496; B: F342, N343, T345, V367, L368, S371, A372, S373, F374, W436, N440, L441
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of S2M11 Fab on SARS-CoV-2 Epsilon S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, R452, L455, F456, E484, G485, F486, Y489, F490, L492, Q493, S494, G496; B: F342, N343, T345, V367, L368, S371, A372, S373, F374, W436, N440, L441
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of S2M11 Fab on SARS-CoV-2 Epsilon S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, R452, L455, F456, E484, G485, F486, Y489, F490, L492, Q493, S494, G496; B: F342, N343, T345, V367, L368, S371, A372, S373, F374, W436, N440, L441
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of S2M11 Fab on SARS-CoV-2 Epsilon S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, R452, L455, F456, E484, G485, F486, Y489, F490, L492, Q493, S494, G496; B: F342, N343, T345, V367, L368, S371, A372, S373, F374, W436, N440, L441
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of S2M11 Fab on SARS-CoV-2 Epsilon S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, R452, L455, F456, E484, G485, F486, Y489, F490, L492, Q493, S494, G496; B: F342, N343, T345, V367, L368, S371, A372, S373, F374, W436, N440, L441
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 D614G S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, L452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QJW69151.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VH ab6 on SARS-CoV-2 Epsilon S
Chemical type: Discontinuous protein residues
Discontinuous residues: K444, G447, N448, Y449, N450, R452, L455, I468, T470, I472, C480, G482, V483, N487, C488, Y489, F490, Q493, S494
Source molecule (GenBank): QTC60823.1
Assay category: BCell
Result: Positive