Reference: Rachel H Fong; Soma S R Banik; Kimberly Mattia; Trevor Barnes; David Tucker; Nathan Liss; Kai Lu; Suganya Selvarajah; Surabhi Srinivasan; Manu Mabila; Adam Miller; Marcus O Muench; Alain Michault; Joseph B Rucker; Cheryl Paes; Graham Simmons; Kristen M Kahle; Benjamin J Doranz. "Exposure of epitope residues on the outer face of the chikungunya virus envelope trimer determines antibody neutralizing efficacy." Journal of virology (2014).

Epitope: mAb IM-CKV057 and IM-CKV067
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: mAb IM-CKV057 and IM-CKV067
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: mAb IM-CKV057 and IM-CKV067
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-Low

Epitope: mAb IM-CKV057 and IM-CKV067
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Negative

Epitope: mAb IM-CKV057 and IM-CKV067
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: mAb IM-CKV057 and IM-CKV067
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Negative

Epitope: mAb IM-CKV061 and IM-CKV062
Chemical type: Discontinuous protein residues
Discontinuous residues: M592, W898, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: mAb IM-CKV061 and IM-CKV062
Chemical type: Discontinuous protein residues
Discontinuous residues: M592, W898, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-High

Epitope: mAb IM-CKV061 and IM-CKV062
Chemical type: Discontinuous protein residues
Discontinuous residues: M592, W898, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Negative

Epitope: mAb IM-CKV061 and IM-CKV062
Chemical type: Discontinuous protein residues
Discontinuous residues: M592, W898, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-High

Epitope: mAb IM-CKV061 and IM-CKV062
Chemical type: Discontinuous protein residues
Discontinuous residues: M592, W898, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-High

Epitope: mAb IM-CKV063
Chemical type: Discontinuous protein residues
Discontinuous residues: E349, G380, W389, K391, R405, I446
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: mAb IM-CKV063
Chemical type: Discontinuous protein residues
Discontinuous residues: E349, G380, W389, K391, R405, I446
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: mAb IM-CKV063
Chemical type: Discontinuous protein residues
Discontinuous residues: E349, G380, W389, K391, R405, I446
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: mAb IM-CKV063
Chemical type: Discontinuous protein residues
Discontinuous residues: E349, G380, W389, K391, R405, I446
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000094

Epitope: mAb IM-CKV063
Chemical type: Discontinuous protein residues
Discontinuous residues: E349, G380, W389, K391, R405, I446
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive
Quantitative measurement: 0.32

Epitope: mAb IM-CKV063
Chemical type: Discontinuous protein residues
Discontinuous residues: E349, G380, W389, K391, R405, I446
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive
Quantitative measurement: 290000.0

Epitope: mAb IM-CKV063
Chemical type: Discontinuous protein residues
Discontinuous residues: E349, G380, W389, K391, R405, I446
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-High

Epitope: mAb IM-CKV063
Chemical type: Discontinuous protein residues
Discontinuous residues: E349, G380, W389, K391, R405, I446
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-High

Epitope: mAb IM-CKV063
Chemical type: Discontinuous protein residues
Discontinuous residues: E349, G380, W389, K391, R405, I446
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: mAb IM-CKV065
Chemical type: Discontinuous protein residues
Discontinuous residues: H398, I399, H424, M496, Q520, T521, Y524, C526, G534, T537, N556, K558
Source molecule (GenBank): NP_690589.2
Assay category: BCell
Result: Positive

Epitope: mAb IM-CKV065
Chemical type: Discontinuous protein residues
Discontinuous residues: H398, I399, H424, M496, Q520, T521, Y524, C526, G534, T537, N556, K558
Source molecule (GenBank): NP_690589.2
Assay category: BCell
Result: Positive
Quantitative measurement: 160000.0

Epitope: mAb IM-CKV065
Chemical type: Discontinuous protein residues
Discontinuous residues: H398, I399, H424, M496, Q520, T521, Y524, C526, G534, T537, N556, K558
Source molecule (GenBank): NP_690589.2
Assay category: BCell
Result: Positive

Epitope: mAb IM-CKV065
Chemical type: Discontinuous protein residues
Discontinuous residues: H398, I399, H424, M496, Q520, T521, Y524, C526, G534, T537, N556, K558
Source molecule (GenBank): NP_690589.2
Assay category: BCell
Result: Positive
Quantitative measurement: 9.3

Epitope: mAb IM-CKV065
Chemical type: Discontinuous protein residues
Discontinuous residues: H398, I399, H424, M496, Q520, T521, Y524, C526, G534, T537, N556, K558
Source molecule (GenBank): NP_690589.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0015

Epitope: mAb IM-CKV065
Chemical type: Discontinuous protein residues
Discontinuous residues: H398, I399, H424, M496, Q520, T521, Y524, C526, G534, T537, N556, K558
Source molecule (GenBank): NP_690589.2
Assay category: BCell
Result: Negative

Epitope: mAb IM-CKV065
Chemical type: Discontinuous protein residues
Discontinuous residues: H398, I399, H424, M496, Q520, T521, Y524, C526, G534, T537, N556, K558
Source molecule (GenBank): NP_690589.2
Assay category: BCell
Result: Positive-Intermediate

Epitope: mAb IM-CKV066
Chemical type: Discontinuous protein residues
Discontinuous residues: Q471, G892, Y894, F896, D906, T1037, V1038
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: mAb IM-CKV066
Chemical type: Discontinuous protein residues
Discontinuous residues: Q471, G892, Y894, F896, D906, T1037, V1038
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Negative

Epitope: mAb C9
Chemical type: Discontinuous protein residues
Discontinuous residues: A487
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: mAb C9
Chemical type: Discontinuous protein residues
Discontinuous residues: A487
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: mAb C9
Chemical type: Discontinuous protein residues
Discontinuous residues: A487
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive
Quantitative measurement: 1.2

Epitope: mAb C9
Chemical type: Discontinuous protein residues
Discontinuous residues: A487
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-High

Epitope: mAb C9
Chemical type: Discontinuous protein residues
Discontinuous residues: A487
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-High

Epitope: mAb C9
Chemical type: Discontinuous protein residues
Discontinuous residues: A487
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive