Reference: Yimeng Wang; Andrey Galkin; Xiaoran Shang; Alexander Marin; Shaohua Jin; Ting-Juan Ye; Shridhar Bale; Chi-I Chiang; Ananda Chowdhury; Agnes L Chenine; Ashley Turonis; Jack Greenhouse; Rebecca Stone; Jaclyn Wear; Swagata Kar; Hanne Andersen; Yan-Jang S Huang; Dana L Vanlandingham; Stephen Higgs; Rena G Lapidus; Thomas Fuerst; David J Weber; Richard T Wyatt; Christel Iffland; Theodore C Pierson; Alexander K Andrianov; Edwin Pozharski; Yuxing Li. "Rational design of flavivirus E protein vaccine optimizes immunogenicity and mitigates antibody dependent enhancement risk." Nature communications (2025).

Epitope: Epitope of Fab SMZAb2 on ZIKV sE dimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K606, Q621, N661; B: D357, M358, S360, S362, R363, C364, Q367, L372, D373, V387, R389, N393, L403, T405, R542, Q543
Source molecule (GenBank): ALU33341.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab SMZAb2 on ZIKV sE dimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K606, Q621, N661; B: D357, M358, S360, S362, R363, C364, Q367, L372, D373, V387, R389, N393, L403, T405, R542, Q543
Source molecule (GenBank): ALU33341.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab OZ-D4 on ZIKV sE dimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: T603, F604, T605, I607, T687, H688; B: R363, T366, Q367, G368, E369, C395, G396, L397
Source molecule (GenBank): ALU33341.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00010
Host: F 20-21 weeks

Epitope: Epitope of Fab OZ-D4 on ZIKV sE dimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: T603, F604, T605, I607, T687, H688; B: R363, T366, Q367, G368, E369, C395, G396, L397
Source molecule (GenBank): ALU33341.1
Assay category: BCell
Result: Positive
Quantitative measurement: 208000.0
Host: F 20-21 weeks

Epitope: Epitope of Fab OZ-D4 on ZIKV sE dimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: T603, F604, T605, I607, T687, H688; B: R363, T366, Q367, G368, E369, C395, G396, L397
Source molecule (GenBank): ALU33341.1
Assay category: BCell
Result: Positive
Host: F 20-21 weeks

Epitope: Epitope of Fab OZ-D4 on ZIKV sE dimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: T603, F604, T605, I607, T687, H688; B: R363, T366, Q367, G368, E369, C395, G396, L397
Source molecule (GenBank): ALU33341.1
Assay category: BCell
Result: Positive
Host: F 20-21 weeks

Epitope: Epitope of Fab OZ-D4 on ZIKV sE dimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: T603, F604, T605, I607, T687, H688; B: R363, T366, Q367, G368, E369, C395, G396, L397
Source molecule (GenBank): ALU33341.1
Assay category: BCell
Result: Positive
Host: F 20-21 weeks

Epitope: Epitope of Fab OZ-D4 on ZIKV sE dimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: T603, F604, T605, I607, T687, H688; B: R363, T366, Q367, G368, E369, C395, G396, L397
Source molecule (GenBank): ALU33341.1
Assay category: BCell
Result: Positive
Host: F 20-21 weeks

Epitope: Epitope of Fab OZ-D4 on ZIKV sE dimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: T603, F604, T605, I607, T687, H688; B: R363, T366, Q367, G368, E369, C395, G396, L397
Source molecule (GenBank): ALU33341.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: F 20-21 weeks