Reference: Minako Oshima; Philip Deitiker; Joseph Jankovic; M Zouhair Atassi. "Submolecular recognition regions of the H<sub>N</sub> domain of the heavy chain of botulinum neurotoxin type A by T cells from toxin-treated cervical dystonia patients." Journal of neuroimmunology (2016).

Epitope: N1
Chemical type: Peptide from protein
Sequence: ALNDLCIKVNNWDLFFSPS
Position: 449-467
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N2
Chemical type: Peptide from protein
Sequence: FFSPSEDNFTNDLNKGEEI
Position: 463-481
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N3
Chemical type: Peptide from protein
Sequence: KGEEITSDTNIEAAEENIS
Position: 477-495
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N4
Chemical type: Peptide from protein
Sequence: EENISLDLIQQYYLTFNFD
Position: 491-509
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N5
Chemical type: Peptide from protein
Sequence: TFNFDNEPENISIENLSSD
Position: 505-523
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N6
Chemical type: Peptide from protein
Sequence: NLSSDIIGQLELMPNIERF
Position: 519-537
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N7
Chemical type: Peptide from protein
Sequence: NIERFPNGKKYELDKYTMF
Position: 533-551
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N9
Chemical type: Peptide from protein
Sequence: HGKSRIALTNSVNEALLNP
Position: 561-579
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N10
Chemical type: Peptide from protein
Sequence: ALLNPSRVYTFFSSDYVKK
Position: 575-593
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Negative
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N11
Chemical type: Peptide from protein
Sequence: DYVKKVNKATEAAMFLGWV
Position: 589-607
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N12
Chemical type: Peptide from protein
Sequence: FLGWVEQLVYDFTDETSEV
Position: 603-621
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N13
Chemical type: Peptide from protein
Sequence: ETSEVSTTDKIADITIIIP
Position: 617-635
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Negative
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N14
Chemical type: Peptide from protein
Sequence: TIIIPYIGPALNIGNMLYK
Position: 631-649
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N15
Chemical type: Peptide from protein
Sequence: NMLYKDDFVGALIFSGAVI
Position: 645-663
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N16
Chemical type: Peptide from protein
Sequence: SGAVILLEFIPEIAIPVLG
Position: 659-677
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N17
Chemical type: Peptide from protein
Sequence: IPVLGTFALVSYIANKVLT
Position: 673-691
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Negative
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N19
Chemical type: Peptide from protein
Sequence: KRNEKWDEVYKYIVTNWLA
Position: 701-719
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N20
Chemical type: Peptide from protein
Sequence: TNWLAKVNTQIDLIRKKMK
Position: 715-733
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N21
Chemical type: Peptide from protein
Sequence: RKKMKEALENQAEATKAII
Position: 729-747
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N22
Chemical type: Peptide from protein
Sequence: TKAIINYQYNQYTEEEKNN
Position: 743-761
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N23
Chemical type: Peptide from protein
Sequence: EEKNNINFNIDDLSSKLNE
Position: 757-775
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N24
Chemical type: Peptide from protein
Sequence: SKLNESINKAMININKFLN
Position: 771-789
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N25
Chemical type: Peptide from protein
Sequence: NKFLNQCSVSYLMNSMIPY
Position: 785-803
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N26
Chemical type: Peptide from protein
Sequence: SMIPYGVKRLEDFDASLKD
Position: 799-817
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N28
Chemical type: Peptide from protein
Sequence: RGTLIGQVDRLKDKVNNTL
Position: 827-845
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N29
Chemical type: Peptide from protein
Sequence: VNNTLSTDIPFQLSKYVDN
Position: 841-859
Source molecule (GenBank): WP_011948511.1
Assay category: TCell
Result: Positive
Host:  45-72 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo