Reference: Jun Zhou; Jingjing Li; Indira Guleria; Tianqi Chen; Anita Giobbie-Hurder; Jonathan Stevens; Meghna Gupta; Xinqi Wu; Ryan C Brennick; Michael P Manos; F Stephen Hodi. "Immunity to X-linked inhibitor of apoptosis protein (XIAP) in malignant melanoma and check-point blockade." Cancer immunology, immunotherapy : CII (2019).

Epitope: XIAP-1
Chemical type: Peptide from protein
Sequence: MTFNSFEGSKTCVPADI
Position: 1-17
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-2
Chemical type: Peptide from protein
Sequence: GSKTCVPADINKEEEFV
Position: 8-24
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-3
Chemical type: Peptide from protein
Sequence: ADINKEEEFVEEFNRLK
Position: 15-31
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-4
Chemical type: Peptide from protein
Sequence: EFVEEFNRLKTFANF
Position: 22-36
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-4
Chemical type: Peptide from protein
Sequence: EFVEEFNRLKTFANF
Position: 22-36
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-5
Chemical type: Peptide from protein
Sequence: FNRLKTFANFPSGSPVSA
Position: 27-44
Source molecule (GenBank): AAC50373.1
Assay category: BCell
Result: Negative

Epitope: XIAP-5
Chemical type: Peptide from protein
Sequence: FNRLKTFANFPSGSPVSA
Position: 27-44
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-5
Chemical type: Peptide from protein
Sequence: FNRLKTFANFPSGSPVSA
Position: 27-44
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-6
Chemical type: Peptide from protein
Sequence: NFPSGSPVSASTLARAGF
Position: 35-52
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-7
Chemical type: Peptide from protein
Sequence: SASTLARAGFLYTGEGDTV
Position: 43-61
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-8
Chemical type: Peptide from protein
Sequence: FLYTGEGDTVRCFSCHAA
Position: 52-69
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-9
Chemical type: Peptide from protein
Sequence: TVRCFSCHAAVDRWQY
Position: 60-75
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-10
Chemical type: Peptide from protein
Sequence: CHAAVDRWQYGDSAVGRH
Position: 66-83
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-11
Chemical type: Peptide from protein
Sequence: WQYGDSAVGRHRKVSPNCR
Position: 73-91
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-12
Chemical type: Peptide from protein
Sequence: RHRKVSPNCRFINGFYL
Position: 82-98
Source molecule (GenBank): AAC50373.1
Assay category: BCell
Result: Positive-Low

Epitope: XIAP-12
Chemical type: Peptide from protein
Sequence: RHRKVSPNCRFINGFYL
Position: 82-98
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-12
Chemical type: Peptide from protein
Sequence: RHRKVSPNCRFINGFYL
Position: 82-98
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-14
Chemical type: Peptide from protein
Sequence: YLENSATQSTNSGIQNGQY
Position: 97-115
Source molecule (GenBank): AAC50373.1
Assay category: BCell
Result: Positive

Epitope: XIAP-14
Chemical type: Peptide from protein
Sequence: YLENSATQSTNSGIQNGQY
Position: 97-115
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-14
Chemical type: Peptide from protein
Sequence: YLENSATQSTNSGIQNGQY
Position: 97-115
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-15
Chemical type: Peptide from protein
Sequence: TNSGIQNGQYKVENYL
Position: 106-121
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-16
Chemical type: Peptide from protein
Sequence: NGQYKVENYLGSRDHFAL
Position: 112-129
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-16
Chemical type: Peptide from protein
Sequence: NGQYKVENYLGSRDHFAL
Position: 112-129
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-17
Chemical type: Peptide from protein
Sequence: YLGSRDHFALDRPSETHA
Position: 120-137
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-18
Chemical type: Peptide from protein
Sequence: ALDRPSETHADYLLR
Position: 128-142
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-19
Chemical type: Peptide from protein
Sequence: SETHADYLLRTGQVVDI
Position: 133-149
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-21
Chemical type: Peptide from protein
Sequence: VDISDTIYPRNPAMY
Position: 147-161
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-22
Chemical type: Peptide from protein
Sequence: TIYPRNPAMYCEEARLK
Position: 152-168
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-23
Chemical type: Peptide from protein
Sequence: AMYCEEARLKSFQNWPDY
Position: 159-176
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-24
Chemical type: Peptide from protein
Sequence: LKSFQNWPDYAHLTPREL
Position: 167-184
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-25
Chemical type: Peptide from protein
Sequence: DYAHLTPRELASAGLYY
Position: 175-191
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-26
Chemical type: Peptide from protein
Sequence: RELASAGLYYTGIGDQV
Position: 182-198
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-27
Chemical type: Peptide from protein
Sequence: LYYTGIGDQVQCFCCGGK
Position: 189-206
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-28
Chemical type: Peptide from protein
Sequence: DQVQCFCCGGKLKNW
Position: 196-210
Source molecule (GenBank): AAC50373.1
Assay category: BCell
Result: Positive

Epitope: XIAP-28
Chemical type: Peptide from protein
Sequence: DQVQCFCCGGKLKNW
Position: 196-210
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-28
Chemical type: Peptide from protein
Sequence: DQVQCFCCGGKLKNW
Position: 196-210
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-28
Chemical type: Peptide from protein
Sequence: DQVQCFCCGGKLKNW
Position: 196-210
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: XIAP-29
Chemical type: Peptide from protein
Sequence: FCCGGKLKNWEPCDRAW
Position: 201-217
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-30
Chemical type: Peptide from protein
Sequence: KNWEPCDRAWSEHRRHF
Position: 208-224
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-31
Chemical type: Peptide from protein
Sequence: RAWSEHRRHFPNCFFVL
Position: 215-231
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-32
Chemical type: Peptide from protein
Sequence: RHFPNCFFVLGRNLNIR
Position: 222-238
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-32
Chemical type: Peptide from protein
Sequence: RHFPNCFFVLGRNLNIR
Position: 222-238
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-32
Chemical type: Peptide from protein
Sequence: RHFPNCFFVLGRNLNIR
Position: 222-238
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: XIAP-34
Chemical type: Peptide from protein
Sequence: LNIRSESDAVSSDRNF
Position: 235-250
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-35
Chemical type: Peptide from protein
Sequence: SDAVSSDRNFPNSTNLPR
Position: 241-258
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-36
Chemical type: Peptide from protein
Sequence: NFPNSTNLPRNPSMADY
Position: 249-265
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-37
Chemical type: Peptide from protein
Sequence: LPRNPSMADYEARIFTF
Position: 256-272
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-38
Chemical type: Peptide from protein
Sequence: ADYEARIFTFGTWIYSV
Position: 263-279
Source molecule (GenBank): AAC50373.1
Assay category: BCell
Result: Negative

Epitope: XIAP-38
Chemical type: Peptide from protein
Sequence: ADYEARIFTFGTWIYSV
Position: 263-279
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-38
Chemical type: Peptide from protein
Sequence: ADYEARIFTFGTWIYSV
Position: 263-279
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-38
Chemical type: Peptide from protein
Sequence: ADYEARIFTFGTWIYSV
Position: 263-279
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: XIAP-39
Chemical type: Peptide from protein
Sequence: FTFGTWIYSVNKEQLARA
Position: 270-287
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-39
Chemical type: Peptide from protein
Sequence: FTFGTWIYSVNKEQLARA
Position: 270-287
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-40
Chemical type: Peptide from protein
Sequence: SVNKEQLARAGFYAL
Position: 278-292
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-42
Chemical type: Peptide from protein
Sequence: YALGEGDKVKCFHCGGGL
Position: 290-307
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-43
Chemical type: Peptide from protein
Sequence: VKCFHCGGGLTDWKPSEDPW
Position: 298-317
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-44
Chemical type: Peptide from protein
Sequence: TDWKPSEDPWEQHAKWY
Position: 308-324
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-45
Chemical type: Peptide from protein
Sequence: DPWEQHAKWYPGCKYLL
Position: 315-331
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-46
Chemical type: Peptide from protein
Sequence: KWYPGCKYLLEQKGQEYI
Position: 322-339
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-47
Chemical type: Peptide from protein
Sequence: LLEQKGQEYINNIHLTH
Position: 330-346
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-48
Chemical type: Peptide from protein
Sequence: EYINNIHLTHSLEECLVR
Position: 337-354
Source molecule (GenBank): AAC50373.1
Assay category: BCell
Result: Positive

Epitope: XIAP-48
Chemical type: Peptide from protein
Sequence: EYINNIHLTHSLEECLVR
Position: 337-354
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-49
Chemical type: Peptide from protein
Sequence: THSLEECLVRTTEKTPSL
Position: 345-362
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-50
Chemical type: Peptide from protein
Sequence: VRTTEKTPSLTRRIDDTI
Position: 353-370
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-51
Chemical type: Peptide from protein
Sequence: SLTRRIDDTIFQNPMV
Position: 361-376
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-52
Chemical type: Peptide from protein
Sequence: DDTIFQNPMVQEAIRMGF
Position: 367-384
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-53
Chemical type: Peptide from protein
Sequence: MVQEAIRMGFSFKDIKKI
Position: 375-392
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-54
Chemical type: Peptide from protein
Sequence: GFSFKDIKKIMEEKIQI
Position: 383-399
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-55
Chemical type: Peptide from protein
Sequence: KKIMEEKIQISGSNYKSL
Position: 390-407
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-56
Chemical type: Peptide from protein
Sequence: IQISGSNYKSLEVLVADL
Position: 397-414
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-57
Chemical type: Peptide from protein
Sequence: KSLEVLVADLVNAQKDSM
Position: 405-422
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-58
Chemical type: Peptide from protein
Sequence: DLVNAQKDSMQDESSQTSL
Position: 413-431
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-59
Chemical type: Peptide from protein
Sequence: MQDESSQTSLQKEISTEEQL
Position: 422-441
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-60
Chemical type: Peptide from protein
Sequence: LQKEISTEEQLRRLQEEK
Position: 431-448
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-61
Chemical type: Peptide from protein
Sequence: EQLRRLQEEKLCKICMDR
Position: 439-456
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-64
Chemical type: Peptide from protein
Sequence: IVFVPCGHLVTCKQCAE
Position: 460-476
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-65
Chemical type: Peptide from protein
Sequence: LVTCKQCAEAVDKCPMCY
Position: 468-485
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: XIAP-67
Chemical type: Peptide from protein
Sequence: CYTVITFKQKIFMS
Position: 484-497
Source molecule (GenBank): AAC50373.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated