Reference: David K Cole; Anna M Bulek; Garry Dolton; Andrea J Schauenberg; Barbara Szomolay; William Rittase; Andrew Trimby; Prithiviraj Jothikumar; Anna Fuller; Ania Skowera; Jamie Rossjohn; Cheng Zhu; John J Miles; Mark Peakman; Linda Wooldridge; Pierre J Rizkallah; Andrew K Sewell. "Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity." The Journal of clinical investigation (2016).

Epitope: MVW
Chemical type: Peptide from protein
Sequence: MVWGPDPLYV
Position: 124-133
Source molecule (GenBank): WP_011203743.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MVW
Chemical type: Peptide from protein
Sequence: MVWGPDPLYV
Position: 124-133
Source molecule (GenBank): WP_011203743.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MVW
Chemical type: Peptide from protein
Sequence: MVWGPDPLYV
Position: 124-133
Source molecule (GenBank): WP_011203743.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: MVW
Chemical type: Peptide from protein
Sequence: MVWGPDPLYV
Position: 124-133
Source molecule (GenBank): WP_011203743.1
Assay category: TCell
Result: Positive
Quantitative measurement: 600000.0

Epitope: MVW
Chemical type: Peptide from protein
Sequence: MVWGPDPLYV
Position: 124-133
Source molecule (GenBank): WP_011203743.1
Assay category: TCell
Result: Positive
Quantitative measurement: 2.46

Epitope: MVW
Chemical type: Peptide from protein
Sequence: MVWGPDPLYV
Position: 124-133
Source molecule (GenBank): WP_011203743.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.39

Epitope: MVW
Chemical type: Peptide from protein
Sequence: MVWGPDPLYV
Position: 124-133
Source molecule (GenBank): WP_011203743.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.46

Epitope: MVW
Chemical type: Peptide from protein
Sequence: MVWGPDPLYV
Position: 124-133
Source molecule (GenBank): WP_011203743.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 56.7

Epitope: YLG
Chemical type: Peptide, no natural source
Sequence: YLGGPDFPTI
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: YLG
Chemical type: Peptide, no natural source
Sequence: YLGGPDFPTI
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: YLG
Chemical type: Peptide, no natural source
Sequence: YLGGPDFPTI
Assay category: TCell
Result: Positive
Quantitative measurement: 400000.0

Epitope: YLG
Chemical type: Peptide, no natural source
Sequence: YLGGPDFPTI
Assay category: TCell
Result: Positive
Quantitative measurement: 2.47

Epitope: YLG
Chemical type: Peptide, no natural source
Sequence: YLGGPDFPTI
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: YLG
Chemical type: Peptide, no natural source
Sequence: YLGGPDFPTI
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.37

Epitope: YLG
Chemical type: Peptide, no natural source
Sequence: YLGGPDFPTI
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.47

Epitope: YLG
Chemical type: Peptide, no natural source
Sequence: YLGGPDFPTI
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 52.2

Epitope: AQW
Chemical type: Peptide, no natural source
Sequence: AQWGPDPAAA
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: AQW
Chemical type: Peptide, no natural source
Sequence: AQWGPDPAAA
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: AQW
Chemical type: Peptide, no natural source
Sequence: AQWGPDPAAA
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: AQW
Chemical type: Peptide, no natural source
Sequence: AQWGPDPAAA
Assay category: TCell
Result: Positive
Quantitative measurement: 61900.0

Epitope: AQW
Chemical type: Peptide, no natural source
Sequence: AQWGPDPAAA
Assay category: TCell
Result: Positive
Quantitative measurement: 3.06

Epitope: AQW
Chemical type: Peptide, no natural source
Sequence: AQWGPDPAAA
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.68

Epitope: AQW
Chemical type: Peptide, no natural source
Sequence: AQWGPDPAAA
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 3.06

Epitope: AQW
Chemical type: Peptide, no natural source
Sequence: AQWGPDPAAA
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 52.8

Epitope: RQF(A)
Chemical type: Peptide from protein
Sequence: RQFGPDWIVA
Position: 79-88
Source molecule (GenBank): WP_040412122.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: RQF(A)
Chemical type: Peptide from protein
Sequence: RQFGPDWIVA
Position: 79-88
Source molecule (GenBank): WP_040412122.1
Assay category: TCell
Result: Positive
Quantitative measurement: 1.97

Epitope: RQF(A)
Chemical type: Peptide from protein
Sequence: RQFGPDWIVA
Position: 79-88
Source molecule (GenBank): WP_040412122.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: RQF(A)
Chemical type: Peptide from protein
Sequence: RQFGPDWIVA
Position: 79-88
Source molecule (GenBank): WP_040412122.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: RQF(A)
Chemical type: Peptide from protein
Sequence: RQFGPDWIVA
Position: 79-88
Source molecule (GenBank): WP_040412122.1
Assay category: TCell
Result: Positive
Quantitative measurement: 44400.0

Epitope: RQF(A)
Chemical type: Peptide from protein
Sequence: RQFGPDWIVA
Position: 79-88
Source molecule (GenBank): WP_040412122.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.64

Epitope: RQF(A)
Chemical type: Peptide from protein
Sequence: RQFGPDWIVA
Position: 79-88
Source molecule (GenBank): WP_040412122.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.97

Epitope: RQF(A)
Chemical type: Peptide from protein
Sequence: RQFGPDWIVA
Position: 79-88
Source molecule (GenBank): WP_040412122.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 49.4

Epitope: RQW
Chemical type: Peptide, no natural source
Sequence: RQWGPDPAAV
Assay category: TCell
Result: Positive
Quantitative measurement: 7800.0

Epitope: RQW
Chemical type: Peptide, no natural source
Sequence: RQWGPDPAAV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: RQW
Chemical type: Peptide, no natural source
Sequence: RQWGPDPAAV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: RQW
Chemical type: Peptide, no natural source
Sequence: RQWGPDPAAV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: RQW
Chemical type: Peptide, no natural source
Sequence: RQWGPDPAAV
Assay category: TCell
Result: Positive
Quantitative measurement: 2.33

Epitope: RQW
Chemical type: Peptide, no natural source
Sequence: RQWGPDPAAV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.46

Epitope: RQW
Chemical type: Peptide, no natural source
Sequence: RQWGPDPAAV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.33

Epitope: RQW
Chemical type: Peptide, no natural source
Sequence: RQWGPDPAAV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 54.3

Epitope: YQF
Chemical type: Peptide, no natural source
Sequence: YQFGPDFPIA
Assay category: TCell
Result: Positive
Quantitative measurement: 7400.0

Epitope: YQF
Chemical type: Peptide, no natural source
Sequence: YQFGPDFPIA
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: YQF
Chemical type: Peptide, no natural source
Sequence: YQFGPDFPIA
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: YQF
Chemical type: Peptide, no natural source
Sequence: YQFGPDFPIA
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: YQF
Chemical type: Peptide, no natural source
Sequence: YQFGPDFPIA
Assay category: TCell
Result: Positive
Quantitative measurement: 2.46

Epitope: YQF
Chemical type: Peptide, no natural source
Sequence: YQFGPDFPIA
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.49

Epitope: YQF
Chemical type: Peptide, no natural source
Sequence: YQFGPDFPIA
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.11

Epitope: YQF
Chemical type: Peptide, no natural source
Sequence: YQFGPDFPIA
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 60.3

Epitope: RQF(I)
Chemical type: Peptide, no natural source
Sequence: RQFGPDFPTI
Assay category: TCell
Result: Positive
Quantitative measurement: 2.03

Epitope: RQF(I)
Chemical type: Peptide, no natural source
Sequence: RQFGPDFPTI
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: RQF(I)
Chemical type: Peptide, no natural source
Sequence: RQFGPDFPTI
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: RQF(I)
Chemical type: Peptide, no natural source
Sequence: RQFGPDFPTI
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: RQF(I)
Chemical type: Peptide, no natural source
Sequence: RQFGPDFPTI
Assay category: TCell
Result: Positive-High
Quantitative measurement: 500.0

Epitope: RQF(I)
Chemical type: Peptide, no natural source
Sequence: RQFGPDFPTI
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.53

Epitope: RQF(I)
Chemical type: Peptide, no natural source
Sequence: RQFGPDFPTI
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.03

Epitope: RQF(I)
Chemical type: Peptide, no natural source
Sequence: RQFGPDFPTI
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 58.8

Epitope: ALW
Chemical type: Peptide from protein
Sequence: ALWGPDPAAA
Position: 15-24
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Quantitative measurement: 208000.0

Epitope: ALW
Chemical type: Peptide from protein
Sequence: ALWGPDPAAA
Position: 15-24
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: ALW
Chemical type: Peptide from protein
Sequence: ALWGPDPAAA
Position: 15-24
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: ALW
Chemical type: Peptide from protein
Sequence: ALWGPDPAAA
Position: 15-24
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: ALW
Chemical type: Peptide from protein
Sequence: ALWGPDPAAA
Position: 15-24
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 60.0