Reference: I Gómez-Touriño; R Simón-Vázquez; J Alonso-Lorenzo; S Arif; C Calviño-Sampedro; Á González-Fernández; E Pena-González; J Rodríguez; J Viñuela-Roldán; J Verdaguer; O J Cordero; M Peakman; R Varela-Calvino. "Characterization of the autoimmune response against the nerve tissue S100β in patients with type 1 diabetes." Clinical and experimental immunology (2015).

Epitope: S100 6-24
Chemical type: Peptide from protein
Sequence: KAMVALIDVFHQYSGREGD
Position: 6-24
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 6-24
Chemical type: Peptide from protein
Sequence: KAMVALIDVFHQYSGREGD
Position: 6-24
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 7-24
Chemical type: Peptide from protein
Sequence: AMVALIDVFHQYSGREGDK
Position: 7-25
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 7-24
Chemical type: Peptide from protein
Sequence: AMVALIDVFHQYSGREGDK
Position: 7-25
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 2–20
Chemical type: Peptide from protein
Sequence: SELEKAMVALIDVFHQYSG
Position: 2-20
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 1-23
Chemical type: Peptide from protein
Sequence: MSELEKAMVALIDVFHQYSGREG
Position: 1-23
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 21-31
Chemical type: Peptide from protein
Sequence: REGDKHKLKKS
Position: 21-31
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 21-31
Chemical type: Peptide from protein
Sequence: REGDKHKLKKS
Position: 21-31
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 26-33
Chemical type: Peptide from protein
Sequence: HKLKKSELKEL
Position: 26-36
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 26-33
Chemical type: Peptide from protein
Sequence: HKLKKSELKEL
Position: 26-36
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 31-49
Chemical type: Peptide from protein
Sequence: SELKELINNELSHFLEEIK
Position: 31-49
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 30-48
Chemical type: Peptide from protein
Sequence: KSELKELINNELSHFLEEI
Position: 30-48
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 20-39
Chemical type: Peptide from protein
Sequence: GREGDKHKLKKSELKELINN
Position: 20-39
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 22-41
Chemical type: Peptide from protein
Sequence: EGDKHKLKKSELKELINNEL
Position: 22-41
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 19-39
Chemical type: Peptide from protein
Sequence: SGREGDKHKLKKSELKELINN
Position: 19-39
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 19-39
Chemical type: Peptide from protein
Sequence: SGREGDKHKLKKSELKELINN
Position: 19-39
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Negative

Epitope: S100 25-46
Chemical type: Peptide from protein
Sequence: KHKLKKSELKELINNELSHFLE
Position: 25-46
Source molecule (GenBank): AAH01766.1
Assay category: TCell
Result: Positive
Host:  mean: 49.2 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S100 25-46
Chemical type: Peptide from protein
Sequence: KHKLKKSELKELINNELSHFLE
Position: 25-46
Source molecule (GenBank): AAH01766.1
Assay category: TCell
Result: Positive
Host:  mean: 30 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S100 25-46
Chemical type: Peptide from protein
Sequence: KHKLKKSELKELINNELSHFLE
Position: 25-46
Source molecule (GenBank): AAH01766.1
Assay category: TCell
Result: Positive
Host:  mean: 49.2 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S100 25-46
Chemical type: Peptide from protein
Sequence: KHKLKKSELKELINNELSHFLE
Position: 25-46
Source molecule (GenBank): AAH01766.1
Assay category: TCell
Result: Positive
Host:  mean: 30 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S100 25-46
Chemical type: Peptide from protein
Sequence: KHKLKKSELKELINNELSHFLE
Position: 25-46
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 25-46
Chemical type: Peptide from protein
Sequence: KHKLKKSELKELINNELSHFLE
Position: 25-46
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Negative

Epitope: S100 73-85
Chemical type: Peptide from protein
Sequence: EFMAFVAMVTTAC
Position: 73-85
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 73-85
Chemical type: Peptide from protein
Sequence: EFMAFVAMVTTAC
Position: 73-85
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 71-82
Chemical type: Peptide from protein
Sequence: FQEFMAFVAMVT
Position: 71-82
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 71-82
Chemical type: Peptide from protein
Sequence: FQEFMAFVAMVT
Position: 71-82
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 71-84
Chemical type: Peptide from protein
Sequence: FQEFMAFVAMVTTA
Position: 71-84
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 70-80
Chemical type: Peptide from protein
Sequence: DFQEFMAFVAMVTTACHEFFE
Position: 70-90
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 71-92
Chemical type: Peptide from protein
Sequence: FQEFMAFVAMVTTACHEFFEHE
Position: 71-92
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 71-92
Chemical type: Peptide from protein
Sequence: FQEFMAFVAMVTTACHEFFEHE
Position: 71-92
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 60-86
Chemical type: Peptide from protein
Sequence: TLDNDGDGECDFQEFMAFVAMVTTACH
Position: 60-86
Source molecule (GenBank): AAH01766.1
Assay category: MhcLigandElution
Result: Positive

Epitope: S100 60-86
Chemical type: Peptide from protein
Sequence: TLDNDGDGECDFQEFMAFVAMVTTACH
Position: 60-86
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 6-25
Chemical type: Peptide from protein
Sequence: KAMVALIDVFHQYSGREGDK
Position: 6-25
Source molecule (GenBank): AAH01766.1
Assay category: TCell
Result: Positive
Host:  mean: 30 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S100 6-25
Chemical type: Peptide from protein
Sequence: KAMVALIDVFHQYSGREGDK
Position: 6-25
Source molecule (GenBank): AAH01766.1
Assay category: TCell
Result: Positive
Host:  mean: 49.2 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S100 6-25
Chemical type: Peptide from protein
Sequence: KAMVALIDVFHQYSGREGDK
Position: 6-25
Source molecule (GenBank): AAH01766.1
Assay category: TCell
Result: Positive
Host:  mean: 49.2 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S100 6-25
Chemical type: Peptide from protein
Sequence: KAMVALIDVFHQYSGREGDK
Position: 6-25
Source molecule (GenBank): AAH01766.1
Assay category: TCell
Result: Positive
Host:  mean: 30 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S100 6-25
Chemical type: Peptide from protein
Sequence: KAMVALIDVFHQYSGREGDK
Position: 6-25
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 6-20
Chemical type: Peptide from protein
Sequence: KAMVALIDVFHQYSG
Position: 6-20
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Negative

Epitope: S100 7-21
Chemical type: Peptide from protein
Sequence: AMVALIDVFHQYSGR
Position: 7-21
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 9-23
Chemical type: Peptide from protein
Sequence: VALIDVFHQYSGREG
Position: 9-23
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Negative

Epitope: S100 10-24
Chemical type: Peptide from protein
Sequence: ALIDVFHQYSGREGD
Position: 10-24
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Negative

Epitope: S100 11-25
Chemical type: Peptide from protein
Sequence: LIDVFHQYSGREGDK
Position: 11-25
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 2-25
Chemical type: Peptide from protein
Sequence: SELEKAMVALIDVFHQYSGREGDK
Position: 2-25
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 21-36
Chemical type: Peptide from protein
Sequence: REGDKHKLKKSELKEL
Position: 21-36
Source molecule (GenBank): AAH01766.1
Assay category: TCell
Result: Positive
Host:  mean: 49.2 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S100 21-36
Chemical type: Peptide from protein
Sequence: REGDKHKLKKSELKEL
Position: 21-36
Source molecule (GenBank): AAH01766.1
Assay category: TCell
Result: Negative
Host:  mean: 30 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S100 21-36
Chemical type: Peptide from protein
Sequence: REGDKHKLKKSELKEL
Position: 21-36
Source molecule (GenBank): AAH01766.1
Assay category: TCell
Result: Positive
Host:  mean: 49.2 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S100 21-36
Chemical type: Peptide from protein
Sequence: REGDKHKLKKSELKEL
Position: 21-36
Source molecule (GenBank): AAH01766.1
Assay category: TCell
Result: Negative
Host:  mean: 30 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S100 21-36
Chemical type: Peptide from protein
Sequence: REGDKHKLKKSELKEL
Position: 21-36
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Negative

Epitope: S100 21-35
Chemical type: Peptide from protein
Sequence: REGDKHKLKKSELKE
Position: 21-35
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Negative

Epitope: S100 22-36
Chemical type: Peptide from protein
Sequence: EGDKHKLKKSELKEL
Position: 22-36
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Negative

Epitope: S100 25-39
Chemical type: Peptide from protein
Sequence: KHKLKKSELKELINN
Position: 25-39
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Negative

Epitope: S100 26-40
Chemical type: Peptide from protein
Sequence: HKLKKSELKELINNE
Position: 26-40
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Negative

Epitope: S100 27-41
Chemical type: Peptide from protein
Sequence: KLKKSELKELINNEL
Position: 27-41
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Negative

Epitope: S100 28-42
Chemical type: Peptide from protein
Sequence: LKKSELKELINNELS
Position: 28-42
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Negative

Epitope: S100 29-43
Chemical type: Peptide from protein
Sequence: KKSELKELINNELSH
Position: 29-43
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Negative

Epitope: S100 30-44
Chemical type: Peptide from protein
Sequence: KSELKELINNELSHF
Position: 30-44
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Negative

Epitope: S100 31-45
Chemical type: Peptide from protein
Sequence: SELKELINNELSHFL
Position: 31-45
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Negative

Epitope: S100 32-46
Chemical type: Peptide from protein
Sequence: ELKELINNELSHFLE
Position: 32-46
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Negative

Epitope: S100 68-92
Chemical type: Peptide from protein
Sequence: ECDFQEFMAFVAMVTTACHEFFEHE
Position: 68-92
Source molecule (GenBank): AAH01766.1
Assay category: TCell
Result: Positive
Host:  mean: 49.2 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S100 68-92
Chemical type: Peptide from protein
Sequence: ECDFQEFMAFVAMVTTACHEFFEHE
Position: 68-92
Source molecule (GenBank): AAH01766.1
Assay category: TCell
Result: Positive
Host:  mean: 30 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S100 68-92
Chemical type: Peptide from protein
Sequence: ECDFQEFMAFVAMVTTACHEFFEHE
Position: 68-92
Source molecule (GenBank): AAH01766.1
Assay category: TCell
Result: Positive
Host:  mean: 49.2 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S100 68-92
Chemical type: Peptide from protein
Sequence: ECDFQEFMAFVAMVTTACHEFFEHE
Position: 68-92
Source molecule (GenBank): AAH01766.1
Assay category: TCell
Result: Positive
Host:  mean: 30 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S100 68-92
Chemical type: Peptide from protein
Sequence: ECDFQEFMAFVAMVTTACHEFFEHE
Position: 68-92
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 68-82
Chemical type: Peptide from protein
Sequence: ECDFQEFMAFVAMVT
Position: 68-82
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 69-83
Chemical type: Peptide from protein
Sequence: CDFQEFMAFVAMVTT
Position: 69-83
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 70-84
Chemical type: Peptide from protein
Sequence: DFQEFMAFVAMVTTA
Position: 70-84
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 71-85
Chemical type: Peptide from protein
Sequence: FQEFMAFVAMVTTAC
Position: 71-85
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 72-86
Chemical type: Peptide from protein
Sequence: QEFMAFVAMVTTACH
Position: 72-86
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 73-87
Chemical type: Peptide from protein
Sequence: EFMAFVAMVTTACHE
Position: 73-87
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 74-88
Chemical type: Peptide from protein
Sequence: FMAFVAMVTTACHEF
Position: 74-88
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 75-89
Chemical type: Peptide from protein
Sequence: MAFVAMVTTACHEFF
Position: 75-89
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 76-90
Chemical type: Peptide from protein
Sequence: AFVAMVTTACHEFFE
Position: 76-90
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 77-91
Chemical type: Peptide from protein
Sequence: FVAMVTTACHEFFEH
Position: 77-91
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive

Epitope: S100 78-92
Chemical type: Peptide from protein
Sequence: VAMVTTACHEFFEHE
Position: 78-92
Source molecule (GenBank): AAH01766.1
Assay category: MhcBinding
Result: Positive