Reference: Linda K Myers; Yoshihiko Sakurai; B Tang; Xiaowen He; Edward F Rosloniec; John M Stuart; Andrew H Kang. "Peptide-induced suppression of collagen-induced arthritis in HLA-DR1 transgenic mice." Arthritis and rheumatism (2002).

Epitope: CII(256-276)
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPKGEPGPA
Position: 456-476
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII(256-276)
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPKGEPGPA
Position: 456-476
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII(256-276)
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPKGEPGPA
Position: 456-476
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII(256-276)
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPKGEPGPA
Position: 456-476
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII(256-276)
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPKGEPGPA
Position: 456-476
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII(256-276)
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPKGEPGPA
Position: 456-476
Source molecule (GenBank): P02458.3
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CII(256-276)
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPKGEPGPA
Position: 456-476
Source molecule (GenBank): P02458.3
Assay category: MhcBinding
Result: Positive

Epitope: 263A analog to CII(256-276)
Chemical type: Peptide, no natural source
Sequence: GEPGIAGAKGEQGPKGEPGPA
Assay category: MhcBinding
Result: Negative

Epitope: 263N analog to CII(256-276)
Chemical type: Peptide, no natural source
Sequence: GEPGIAGNKGEQGPKGEPGPA
Assay category: MhcBinding
Result: Negative

Epitope: 265A analog to CII(256-276)
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKAEQGPKGEPGPA
Assay category: MhcBinding
Result: Positive

Epitope: 266D analog to CII(256-276)
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGDQGPKGEPGPA
Assay category: MhcBinding
Result: Negative

Epitope: 266A analog to CII(256-276)
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGAQGPKGEPGPA
Assay category: MhcBinding
Result: Positive

Epitope: 263N,266A analog to CII(256-276)
Chemical type: Peptide, no natural source
Sequence: GEPGIAGNKGAQGPKGEPGPA
Assay category: MhcBinding
Result: Negative

Epitope: 263N,266D analog to CII(256-276)
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGDQGPKGEPGPA
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: 263N,266D analog to CII(256-276)
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGDQGPKGEPGPA
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 263N,266D analog to CII(256-276)
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGDQGPKGEPGPA
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 263N,266D analog to CII(256-276)
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGDQGPKGEPGPA
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 263N,266D analog to CII(256-276)
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGDQGPKGEPGPA
Assay category: MhcBinding
Result: Negative

Epitope: 266D,267T,269A analog to CII(256-276)
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGDTGAKGEPGPA
Assay category: MhcBinding
Result: Positive

Epitope: 260A,261B,263N analog to CII(256-276)
Chemical type: Peptide, no natural source
Sequence: GEPGAPGNKGEQGPKGEPGPA
Assay category: MhcBinding
Result: Negative