Reference: J Schilz; U Binder; L Friedrich; M Gebauer; C Lutz; M Schlapschy; A Schiefner; A Skerra. "Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope." Journal of molecular biology (2021).

Epitope: Epitope of Fab 1.1 and Fab 1.2 on PAS#1
Chemical type: Peptide, no natural source
Sequence: APASPAAPA
Assay category: BCell
Result: Positive
Quantitative measurement: 44.0

Epitope: Epitope of Fab 1.1 and Fab 1.2 on PAS#1
Chemical type: Peptide, no natural source
Sequence: APASPAAPA
Assay category: BCell
Result: Positive
Quantitative measurement: 2.65

Epitope: Epitope of Fab 1.1 and Fab 1.2 on PAS#1
Chemical type: Peptide, no natural source
Sequence: APASPAAPA
Assay category: BCell
Result: Positive
Quantitative measurement: 1.55

Epitope: Epitope of Fab 1.1 and Fab 1.2 on PAS#1
Chemical type: Peptide, no natural source
Sequence: APASPAAPA
Assay category: BCell
Result: Positive
Quantitative measurement: 1.0

Epitope: Epitope of Fab 2.2 on P/A#1
Chemical type: Peptide, no natural source
Sequence: APAPAAPA
Assay category: BCell
Result: Positive
Quantitative measurement: 22.0

Epitope: Epitope of Fab 2.2 on P/A#1
Chemical type: Peptide, no natural source
Sequence: APAPAAPA
Assay category: BCell
Result: Positive
Quantitative measurement: 1.1

Epitope: Epitope of Fab 2.2 on P/A#1
Chemical type: Peptide, no natural source
Sequence: APAPAAPA
Assay category: BCell
Result: Positive
Quantitative measurement: 2.55

Epitope: Epitope of Fab 2.2 on P/A#1
Chemical type: Peptide, no natural source
Sequence: APAPAAPA
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 3.1 on APSA
Chemical type: Peptide, no natural source
Sequence: APSAAPSAAPSA
Assay category: BCell
Result: Positive
Quantitative measurement: 0.019

Epitope: Epitope of Fab 3.1 on APSA
Chemical type: Peptide, no natural source
Sequence: APSAAPSAAPSA
Assay category: BCell
Result: Positive
Quantitative measurement: 1.85

Epitope: Epitope of MAb 2.1 on P/A#1
Chemical type: Peptide, no natural source
Sequence: AAPAAPAPAAPA
Assay category: BCell
Result: Positive

Epitope: Epitope of MAb 2.1 on P/A#1
Chemical type: Peptide, no natural source
Sequence: AAPAAPAPAAPA
Assay category: BCell
Result: Positive
Quantitative measurement: 0.429

Epitope: Epitope of MAb 2.1 on P/A#1
Chemical type: Peptide, no natural source
Sequence: AAPAAPAPAAPA
Assay category: BCell
Result: Positive
Quantitative measurement: 1.7

Epitope: Epitope of MAb 2.2 on PAS#1
Chemical type: Peptide, no natural source
Sequence: ASPAAPAPASPA
Assay category: BCell
Result: Positive
Quantitative measurement: 1.1

Epitope: Epitope of MAb 2.2 on PAS#1
Chemical type: Peptide, no natural source
Sequence: ASPAAPAPASPA
Assay category: BCell
Result: Positive
Quantitative measurement: 22.0

Epitope: Epitope of MAb 2.2 on PAS#1
Chemical type: Peptide, no natural source
Sequence: ASPAAPAPASPA
Assay category: BCell
Result: Positive

Epitope: Epitope of MAb 2.1 on PAS#1
Chemical type: Peptide, no natural source
Sequence: APAPASPAAPAP
Assay category: BCell
Result: Positive

Epitope: Epitope of MAb 2.1 on PAS#1
Chemical type: Peptide, no natural source
Sequence: APAPASPAAPAP
Assay category: BCell
Result: Positive
Quantitative measurement: 0.429

Epitope: Epitope of MAb 2.1 on PAS#1
Chemical type: Peptide, no natural source
Sequence: APAPASPAAPAP
Assay category: BCell
Result: Positive
Quantitative measurement: 1.7

Epitope: Epitope of anti-hu kappa VHH
Chemical type: Discontinuous protein residues
Discontinuous residues: K107, T109, V110, Y140, P141, E143, A144, K145, T197, H198, Q199, G200, L201, S202
Source molecule (GenBank): P0DOX7.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.55

Epitope: Epitope of Fab 3.2 on APSA
Chemical type: Peptide, no natural source
Sequence: AAPSAAPSAA
Assay category: BCell
Result: Positive
Quantitative measurement: 20.0

Epitope: Epitope of Fab 3.2 on APSA
Chemical type: Peptide, no natural source
Sequence: AAPSAAPSAA
Assay category: BCell
Result: Positive
Quantitative measurement: 0.108

Epitope: Epitope of Fab 3.2 on APSA
Chemical type: Peptide, no natural source
Sequence: AAPSAAPSAA
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 3.2 on APSA
Chemical type: Peptide, no natural source
Sequence: AAPSAAPSAA
Assay category: BCell
Result: Positive
Quantitative measurement: 80.0