Reference: Florian Klein; Ron Diskin; Johannes F Scheid; Christian Gaebler; Hugo Mouquet; Ivelin S Georgiev; Marie Pancera; Tongqing Zhou; Reha-Baris Incesu; Brooks Zhongzheng Fu; Priyanthi N P Gnanapragasam; Thiago Y Oliveira; Michael S Seaman; Peter D Kwong; Pamela J Bjorkman; Michel C Nussenzweig. "Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization." Cell (2013).

Epitope: Epitope of Fab 3BNC117 on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: N278, T280, N282, A283, K284, S365, G366, G367, D368, I371, G423, T449, R450, D451, G452, G453, N455, R463, G467
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 3BNC117 on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: N278, T280, N282, A283, K284, S365, G366, G367, D368, I371, G423, T449, R450, D451, G452, G453, N455, R463, G467
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 3BNC117 on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: N278, T280, N282, A283, K284, S365, G366, G367, D368, I371, G423, T449, R450, D451, G452, G453, N455, R463, G467
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 3BNC117 on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: N278, T280, N282, A283, K284, S365, G366, G367, D368, I371, G423, T449, R450, D451, G452, G453, N455, R463, G467
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 3BNC117 on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: N278, T280, N282, A283, K284, S365, G366, G367, D368, I371, G423, T449, R450, D451, G452, G453, N455, R463, G467
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 3BNC117 on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: N278, T280, N282, A283, K284, S365, G366, G367, D368, I371, G423, T449, R450, D451, G452, G453, N455, R463, G467
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.83

Epitope: Epitope of Fab 3BNC117 on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: N278, T280, N282, A283, K284, S365, G366, G367, D368, I371, G423, T449, R450, D451, G452, G453, N455, R463, G467
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 12A21 on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: L121, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, W421, G423, G425, Q426, T449, R450, D451, G452, G453, A454, N456, R463, G467, N468, K470, R474
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 12A21 on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: L121, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, W421, G423, G425, Q426, T449, R450, D451, G452, G453, A454, N456, R463, G467, N468, K470, R474
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 12A21 on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: L121, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, W421, G423, G425, Q426, T449, R450, D451, G452, G453, A454, N456, R463, G467, N468, K470, R474
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 12A21 on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: L121, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, W421, G423, G425, Q426, T449, R450, D451, G452, G453, A454, N456, R463, G467, N468, K470, R474
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.9

Epitope: Epitope of Fab 12A21 on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: L121, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, W421, G423, G425, Q426, T449, R450, D451, G452, G453, A454, N456, R463, G467, N468, K470, R474
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 12A21 on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: L121, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, W421, G423, G425, Q426, T449, R450, D451, G452, G453, A454, N456, R463, G467, N468, K470, R474
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 12A21 on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: L121, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, W421, G423, G425, Q426, T449, R450, D451, G452, G453, A454, N456, R463, G467, N468, K470, R474
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive