Reference: Stephen J Till; Eleanor J Raynsford; Catherine J Reynolds; Kathryn J Quigley; Agnieszka Grzybowska-Kowalczyk; Lavina R Saggar; Andrea Goldstone; Bernard Maillere; William W Kwok; Daniel M Altmann; Stephen R Durham; Rosemary J Boyton. "Peptide-induced immune regulation by a promiscuous and immunodominant CD4T-cell epitope of Timothy grass pollen: a role of Cbl-b and Itch in regulation." Thorax (2014).

Epitope: Phl p 5b p1
Chemical type: Peptide from protein
Sequence: DAGYAPATPAAAGAAAGKAT
Position: 21-40
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p2
Chemical type: Peptide from protein
Sequence: PAAAGAAAGKATTEEQKLIE
Position: 29-48
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p3
Chemical type: Peptide from protein
Sequence: GKATTEEQKLIEDINVGFKA
Position: 37-56
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p4
Chemical type: Peptide from protein
Sequence: KLIEDINVGFKAAVAAAASV
Position: 45-64
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p5
Chemical type: Peptide from protein
Sequence: GFKAAVAAAASVPAADKFKT
Position: 53-72
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p6
Chemical type: Peptide from protein
Sequence: AASVPAADKFKTFEAAFTSS
Position: 61-80
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p7
Chemical type: Peptide from protein
Sequence: KFKTFEAAFTSSSKAAAAKA
Position: 69-88
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p8
Chemical type: Peptide from protein
Sequence: FTSSSKAAAAKAPGLVPKLD
Position: 77-96
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p9
Chemical type: Peptide from protein
Sequence: AAKAPGLVPKLDAAYSVAYK
Position: 85-104
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p10
Chemical type: Peptide from protein
Sequence: PKLDAAYSVAYKAAVGATPE
Position: 93-112
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p11
Chemical type: Peptide from protein
Sequence: VAYKAAVGATPEAKFDSFVA
Position: 101-120
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p12
Chemical type: Peptide from protein
Sequence: ATPEAKFDSFVASLTEALRV
Position: 109-128
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p13
Chemical type: Peptide from protein
Sequence: SFVASLTEALRVIAGALEVH
Position: 117-136
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p14
Chemical type: Peptide from protein
Sequence: ALRVIAGALEVHAVKPVTEE
Position: 125-144
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p15
Chemical type: Peptide from protein
Sequence: LEVHAVKPVTEEPGMAKIPA
Position: 133-152
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p16
Chemical type: Peptide from protein
Sequence: VTEEPGMAKIPAGELQIIDK
Position: 141-160
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p17
Chemical type: Peptide from protein
Sequence: KIPAGELQIIDKIDAAFKVA
Position: 149-168
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p18
Chemical type: Peptide from protein
Sequence: IIDKIDAAFKVAATAAATAP
Position: 157-176
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Positive
Host:  8-14 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: Phl p 5b p18
Chemical type: Peptide from protein
Sequence: IIDKIDAAFKVAATAAATAP
Position: 157-176
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p18
Chemical type: Peptide from protein
Sequence: IIDKIDAAFKVAATAAATAP
Position: 157-176
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phl p 5b p18
Chemical type: Peptide from protein
Sequence: IIDKIDAAFKVAATAAATAP
Position: 157-176
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Phl p 5b p18
Chemical type: Peptide from protein
Sequence: IIDKIDAAFKVAATAAATAP
Position: 157-176
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phl p 5b p18
Chemical type: Peptide from protein
Sequence: IIDKIDAAFKVAATAAATAP
Position: 157-176
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phl p 5b p18
Chemical type: Peptide from protein
Sequence: IIDKIDAAFKVAATAAATAP
Position: 157-176
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Negative

Epitope: Phl p 5b p18
Chemical type: Peptide from protein
Sequence: IIDKIDAAFKVAATAAATAP
Position: 157-176
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Phl p 5b p18
Chemical type: Peptide from protein
Sequence: IIDKIDAAFKVAATAAATAP
Position: 157-176
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Negative

Epitope: Phl p 5b p19
Chemical type: Peptide from protein
Sequence: FKVAATAAATAPADDKFTVF
Position: 165-184
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p20
Chemical type: Peptide from protein
Sequence: ATAPADDKFTVFEAAFNKAI
Position: 173-192
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p21
Chemical type: Peptide from protein
Sequence: FTVFEAAFNKAIKESTGGAY
Position: 181-200
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p23
Chemical type: Peptide from protein
Sequence: GGAYDTYKCIPSLEAAVKQA
Position: 197-216
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Positive
Host:  8-14 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: Phl p 5b p23
Chemical type: Peptide from protein
Sequence: GGAYDTYKCIPSLEAAVKQA
Position: 197-216
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p23
Chemical type: Peptide from protein
Sequence: GGAYDTYKCIPSLEAAVKQA
Position: 197-216
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phl p 5b p23
Chemical type: Peptide from protein
Sequence: GGAYDTYKCIPSLEAAVKQA
Position: 197-216
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phl p 5b p23
Chemical type: Peptide from protein
Sequence: GGAYDTYKCIPSLEAAVKQA
Position: 197-216
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phl p 5b p23
Chemical type: Peptide from protein
Sequence: GGAYDTYKCIPSLEAAVKQA
Position: 197-216
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phl p 5b p23
Chemical type: Peptide from protein
Sequence: GGAYDTYKCIPSLEAAVKQA
Position: 197-216
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Phl p 5b p23
Chemical type: Peptide from protein
Sequence: GGAYDTYKCIPSLEAAVKQA
Position: 197-216
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Negative

Epitope: Phl p 5b p23
Chemical type: Peptide from protein
Sequence: GGAYDTYKCIPSLEAAVKQA
Position: 197-216
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phl p 5b p24
Chemical type: Peptide from protein
Sequence: CIPSLEAAVKQAYAATVAAA
Position: 205-224
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Positive
Host:  26-58 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Positive
Host:  8-14 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host:  25-48 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Positive
Host:  8-14 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Positive
Host:  8-14 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host:  8-14 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Positive
Host:  8-14 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-High

Epitope: Phl p 5b p26
Chemical type: Peptide from protein
Sequence: VAAAPQVKYAVFEAALTKAI
Position: 221-240
Source molecule (GenBank): Q40963.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Phl p 5b p27
Chemical type: Peptide from protein
Sequence: YAVFEAALTKAITAMSEVQK
Position: 229-248
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p28
Chemical type: Peptide from protein
Sequence: TKAITAMSEVQKVSQPATGA
Position: 237-256
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p29
Chemical type: Peptide from protein
Sequence: EVQKVSQPATGAATVAAGAA
Position: 245-264
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p30
Chemical type: Peptide from protein
Sequence: ATGAATVAAGAATTAAGAAS
Position: 253-272
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p31
Chemical type: Peptide from protein
Sequence: AGAATTAAGAASGAATVAAG
Position: 261-280
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Phl p 5b p32
Chemical type: Peptide from protein
Sequence: GAASGAATVAAGGYKV
Position: 269-284
Source molecule (GenBank): Q40963.2
Assay category: TCell
Result: Negative
Host: M 29-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo