Reference: Fangzhu Zhao; Meng Yuan; Celina Keating; Namir Shaabani; Oliver Limbo; Collin Joyce; Jordan Woehl; Shawn Barman; Alison Burns; Quoc Tran; Xueyong Zhu; Michael Ricciardi; Linghang Peng; Jessica Smith; Deli Huang; Bryan Briney; Devin Sok; David Nemazee; John R Teijaro; Ian A Wilson; Dennis R Burton; Joseph G Jardine. "Broadening a SARS-CoV-1-neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution." Science signaling (2023).

Epitope: Epitope of eCR3022.20 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, N370, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, L390, R408, D428, F429, T430, L517
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of eCR3022.20 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, N370, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, L390, R408, D428, F429, T430, L517
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000111

Epitope: Epitope of eCR3022.20 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, N370, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, L390, R408, D428, F429, T430, L517
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.85

Epitope: Epitope of eCR3022.20 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, N370, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, L390, R408, D428, F429, T430, L517
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of eCR3022.20 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, N370, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, L390, R408, D428, F429, T430, L517
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1850000.0

Epitope: Epitope of eCR3022.20 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, N370, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, L390, R408, D428, F429, T430, L517
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000793

Epitope: Epitope of eCR3022.20 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, N370, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, L390, R408, D428, F429, T430, L517
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1550000.0

Epitope: Epitope of eCR3022.20 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, N370, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, L390, R408, D428, F429, T430, L517
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of eCR3022.20 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, N370, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, L390, R408, D428, F429, T430, L517
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of eCR3022.20 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, N370, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, L390, R408, D428, F429, T430, L517
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of eCR3022.20 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, N370, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, L390, R408, D428, F429, T430, L517
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.071

Epitope: Epitope of eCR3022.20 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, N370, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, L390, R408, D428, F429, T430, L517
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0428

Epitope: Epitope of eCR3022.20 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, N370, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, L390, R408, D428, F429, T430, L517
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of CC12.3 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R403, T415, G416, K417, D420, Y421, Y453, L455, F456, R457, K458, N460, Y473, A475, G476, S477, F486, N487, Y489, S494, G496, Q498, N501, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.85

Epitope: Epitope of CC12.3 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R403, T415, G416, K417, D420, Y421, Y453, L455, F456, R457, K458, N460, Y473, A475, G476, S477, F486, N487, Y489, S494, G496, Q498, N501, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive