Reference: Christian Lubich; Katharina Nora Steinitz; Brigitte Hoelbl; Thomas Prenninger; Pauline Maria van Helden; Markus Weiller; Birgit Maria Reipert. "Modulating the microenvironment during FVIII uptake influences the nature of FVIII-peptides presented by antigen-presenting cells." Frontiers in immunology (2022).

Epitope: FVIII 82-102
Chemical type: Peptide from protein
Sequence: DTVVITLKNMASHPVSLHAVG
Position: 101-121
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 82-102
Chemical type: Peptide from protein
Sequence: DTVVITLKNMASHPVSLHAVG
Position: 101-121
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 226-246
Chemical type: Peptide from protein
Sequence: RAWPKMHTVNGYVNRSLPGLI
Position: 245-265
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 226-246
Chemical type: Peptide from protein
Sequence: RAWPKMHTVNGYVNRSLPGLI
Position: 245-265
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 454-474
Chemical type: Peptide from protein
Sequence: YGEVGDTLLIIFKNQASRPYN
Position: 473-493
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 454-474
Chemical type: Peptide from protein
Sequence: YGEVGDTLLIIFKNQASRPYN
Position: 473-493
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 520-543
Chemical type: Peptide from protein
Sequence: GPTKSDPRCLTRYYSSFVNMERDL
Position: 539-562
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 520-543
Chemical type: Peptide from protein
Sequence: GPTKSDPRCLTRYYSSFVNMERDL
Position: 539-562
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 1381-1407
Chemical type: Peptide from protein
Sequence: PQANRSPLPIAKVSSFPSIRPIYLTRV
Position: 1400-1426
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 1381-1407
Chemical type: Peptide from protein
Sequence: PQANRSPLPIAKVSSFPSIRPIYLTRV
Position: 1400-1426
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 1765-1786
Chemical type: Peptide from protein
Sequence: AEVEDNIMVTFRNQASRPYSFY
Position: 1784-1805
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 1765-1786
Chemical type: Peptide from protein
Sequence: AEVEDNIMVTFRNQASRPYSFY
Position: 1784-1805
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 2005-2025
Chemical type: Peptide from protein
Sequence: HLHAGMSTLFLVYSNKCQTPL
Position: 2024-2044
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 2005-2025
Chemical type: Peptide from protein
Sequence: HLHAGMSTLFLVYSNKCQTPL
Position: 2024-2044
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 2140-2164
Chemical type: Peptide from protein
Sequence: FNPPIIARYIRLHPTHYSIRSTLRM
Position: 2159-2183
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 2140-2164
Chemical type: Peptide from protein
Sequence: FNPPIIARYIRLHPTHYSIRSTLRM
Position: 2159-2183
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 2248-2268
Chemical type: Peptide from protein
Sequence: VKSLLTSMYVKEFLISSSQDG
Position: 2267-2287
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: FVIII 2248-2268
Chemical type: Peptide from protein
Sequence: VKSLLTSMYVKEFLISSSQDG
Position: 2267-2287
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)