Reference: Hans Christian Spangenberg; Sergei Viazov; Nadine Kersting; Christoph Neumann-Haefelin; Denise McKinney; Michael Roggendorf; Fritz von Weizsäcker; Hubert E Blum; Robert Thimme. "Intrahepatic CD8+ T-cell failure during chronic hepatitis C virus infection." Hepatology (Baltimore, Md.) (2005).

Epitope: Core 132
Chemical type: Peptide from protein
Sequence: DLMGYIPLV
Position: 132-140
Source molecule (GenBank): AAB67037.1
Assay category: TCell
Result: Negative
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Core 132
Chemical type: Peptide from protein
Sequence: DLMGYIPLV
Position: 132-140
Source molecule (GenBank): AAB67037.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: NS3 1073
Chemical type: Peptide from protein
Sequence: CINGVCWTV
Position: 1073-1081
Source molecule (GenBank): AAB67037.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: NS3 1073
Chemical type: Peptide from protein
Sequence: CINGVCWTV
Position: 1073-1081
Source molecule (GenBank): AAB67037.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: NS3 1406
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1406-1415
Source molecule (GenBank): AAB67037.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: NS3 1406
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1406-1415
Source molecule (GenBank): AAB67037.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: NS3 1406
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1406-1415
Source molecule (GenBank): AAB67037.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 45.0

Epitope: NS3 1406
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1406-1415
Source molecule (GenBank): AAB67037.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 15.0

Epitope: NS3 1406
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1406-1415
Source molecule (GenBank): AAB67037.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 3.7

Epitope: NS3 1406
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1406-1415
Source molecule (GenBank): AAB67037.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 75.0

Epitope: NS5 2594
Chemical type: Peptide from protein
Sequence: ALYDVVTKL
Position: 2144-2152
Source molecule (GenBank): AAA45677.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: NS5 2594
Chemical type: Peptide from protein
Sequence: ALYDVVTKL
Position: 2144-2152
Source molecule (GenBank): AAA45677.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Matrix 58
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): NP_775536.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS5 2594
Chemical type: Peptide from protein
Sequence: ALYDVVSKL
Position: 2594-2602
Source molecule (GenBank): AAB67037.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS5 2594
Chemical type: Peptide from protein
Sequence: ALYDVVSKL
Position: 2594-2602
Source molecule (GenBank): AAB67037.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS3 1073
Chemical type: Peptide from protein
Sequence: CVNGVCWTV
Position: 1073-1081
Source molecule (GenBank): AAY82055.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS3 1073
Chemical type: Peptide from protein
Sequence: CVNGVCWTV
Position: 1073-1081
Source molecule (GenBank): AAY82055.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS3 1406
Chemical type: Peptide from protein
Sequence: KLSALGLNAV
Position: 1406-1415
Source molecule (GenBank): BAA25076.1
Assay category: TCell
Result: Negative
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS3 1406
Chemical type: Peptide from protein
Sequence: KLSALGLNAV
Position: 1406-1415
Source molecule (GenBank): BAA25076.1
Assay category: TCell
Result: Negative
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS3 1406
Chemical type: Peptide from protein
Sequence: KLSSLGLNAV
Position: 1406-1415
Source molecule (GenBank): ABU97067.1
Assay category: TCell
Result: Negative
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS3 1406
Chemical type: Peptide from protein
Sequence: KLSSLGLNAV
Position: 1406-1415
Source molecule (GenBank): ABU97067.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS3 1073
Chemical type: Peptide from protein
Sequence: CINGLCWTV
Position: 47-55
Source molecule (GenBank): CAL46125.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS3 1073
Chemical type: Peptide from protein
Sequence: CINGLCWTV
Position: 47-55
Source molecule (GenBank): CAL46125.1
Assay category: TCell
Result: Negative
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS5 2594
Chemical type: Peptide from protein
Sequence: ALYEVVSKL
Position: 68-76
Source molecule (GenBank): AAB02126.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS5 2594
Chemical type: Peptide from protein
Sequence: ALYEVVSKL
Position: 68-76
Source molecule (GenBank): AAB02126.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS5 2594
Chemical type: Peptide from protein
Sequence: ALYDLVSLL
Assay category: TCell
Result: Negative
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS5 2594
Chemical type: Peptide from protein
Sequence: ALYDLVSLL
Assay category: TCell
Result: Negative
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS3 1406
Chemical type: Peptide from protein
Sequence: KLVAMGVNAV
Position: 1408-1417
Source molecule (GenBank): ACA50667.1
Assay category: TCell
Result: Negative
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS3 1406
Chemical type: Peptide from protein
Sequence: KLVAMGVNAV
Position: 1408-1417
Source molecule (GenBank): ACA50667.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS3 1406
Chemical type: Peptide from protein
Sequence: KLTALGVNAV
Position: 1406-1415
Source molecule (GenBank): ACA50630.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS3 1406
Chemical type: Peptide from protein
Sequence: KLTALGVNAV
Position: 1406-1415
Source molecule (GenBank): ACA50630.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS3 1406
Chemical type: Peptide from protein
Sequence: KLVGLGLNAV
Position: 1406-1415
Source molecule (GenBank): ABW86969.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS3 1406
Chemical type: Peptide from protein
Sequence: KLVGLGLNAV
Position: 1406-1415
Source molecule (GenBank): ABW86969.1
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS3 1406
Chemical type: Peptide from protein
Sequence: KLVGLGLNAV
Position: 1406-1415
Source molecule (GenBank): ABW86969.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 17.0

Epitope: Heterogenous NS3 1406
Chemical type: Peptide from protein
Sequence: KLVGLGLNAV
Position: 1406-1415
Source molecule (GenBank): ABW86969.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 8.2

Epitope: Heterogenous NS3 1406
Chemical type: Peptide from protein
Sequence: KLVGLGLNAV
Position: 1406-1415
Source molecule (GenBank): ABW86969.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 9.0

Epitope: Heterogenous NS3 1406
Chemical type: Peptide from protein
Sequence: KLVGLGLNAV
Position: 1406-1415
Source molecule (GenBank): ABW86969.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 14.0

Epitope: Heterogenous NS3 1406
Chemical type: Peptide from protein
Sequence: KLSGLGLNAI
Assay category: TCell
Result: Positive
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: Heterogenous NS3 1406
Chemical type: Peptide from protein
Sequence: KLSGLGLNAI
Assay category: TCell
Result: Negative
MHC allele types: 235
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo