Reference: Valérie Dutoit; Donatella Ciuffreda; Denis Comte; Jean-Jacques Gonvers; Giuseppe Pantaleo. "Differences in HCV-specific T cell responses between chronic HCV infection and HIV/HCV co-infection." European journal of immunology (2005).

Epitope: HCV NS3-53
Chemical type: Peptide from protein
Sequence: GKSTKVPAAYAAQGY
Position: 1235-1249
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
MHC allele types: 237 245 294 594 337 333
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS5B-119
Chemical type: Peptide from protein
Sequence: SLHSYSPGEINRVAA
Position: 2893-2907
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Negative
MHC allele types: 237 245 294 594 337 333
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS5B-119
Chemical type: Peptide from protein
Sequence: SLHSYSPGEINRVAA
Position: 2893-2907
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS5B-119
Chemical type: Peptide from protein
Sequence: SLHSYSPGEINRVAA
Position: 2893-2907
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
MHC allele types: 237 245 294 594 337 333
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS5B-119
Chemical type: Peptide from protein
Sequence: SLHSYSPGEINRVAA
Position: 2893-2907
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV E2-77
Chemical type: Peptide from protein
Sequence: GLIHLHQNIVDVQYL
Position: 688-702
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
MHC allele types: 242 244 281 574 330 331
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV E2-77
Chemical type: Peptide from protein
Sequence: GLIHLHQNIVDVQYL
Position: 688-702
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
MHC allele types: 242 244 281 574 330 331
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS4A-1
Chemical type: Peptide from protein
Sequence: STWVLVGGVLAALAA
Position: 1658-1672
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
MHC allele types: 242 249 286 294 333 327
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS4A-1
Chemical type: Peptide from protein
Sequence: STWVLVGGVLAALAA
Position: 1658-1672
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
MHC allele types: 242 281 235 341 333
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS4A-1
Chemical type: Peptide from protein
Sequence: STWVLVGGVLAALAA
Position: 1658-1672
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
MHC allele types: 242 244 281 574 330 331 235 341 333
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS4A-1
Chemical type: Peptide from protein
Sequence: STWVLVGGVLAALAA
Position: 1658-1672
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS4A-1
Chemical type: Peptide from protein
Sequence: STWVLVGGVLAALAA
Position: 1658-1672
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS2-37
Chemical type: Peptide from protein
Sequence: TPLRDWAHNGLRDLA
Position: 954-968
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
MHC allele types: 233 235 301 282 338 352
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-95
Chemical type: Peptide from protein
Sequence: LAAKLVALGINAVAY
Position: 1403-1417
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Positive
MHC allele types: 233 235 301 282 352
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS5B-44
Chemical type: Peptide from protein
Sequence: MALYDVVSKLPLAVM
Position: 2593-2607
Source molecule (GenBank): ABR25251.1
Assay category: TCell
Result: Positive
MHC allele types: 233 235 301 282 352
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV p7-7
Chemical type: Peptide from protein
Sequence: FFCFAWYLKGRWVPG
Position: 771-785
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
MHC allele types: 233 235 301 282 352
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV p7-7
Chemical type: Peptide from protein
Sequence: FFCFAWYLKGRWVPG
Position: 771-785
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Negative
MHC allele types: 233 235 301 282 352
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV C-29
Chemical type: Peptide from protein
Sequence: RRRSRNLGKVIDTLT
Position: 113-127
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
MHC allele types: 233 301 295 338 352
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV C-29
Chemical type: Peptide from protein
Sequence: RRRSRNLGKVIDTLT
Position: 113-127
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
MHC allele types: 236 237 286 294 352 353
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-122
Chemical type: Peptide from protein
Sequence: MFDSSVLCECYDAGC
Position: 1511-1525
Source molecule (GenBank): BAA09075.1
Assay category: TCell
Result: Positive
MHC allele types: 244 249 274 295 350 333
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-122
Chemical type: Peptide from protein
Sequence: MFDSSVLCECYDAGC
Position: 1511-1525
Source molecule (GenBank): BAA09075.1
Assay category: TCell
Result: Positive
MHC allele types: 234 249 281 282 334
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-122
Chemical type: Peptide from protein
Sequence: MFDSSVLCECYDAGC
Position: 1511-1525
Source molecule (GenBank): BAA09075.1
Assay category: TCell
Result: Positive
MHC allele types: 233 244 279 295 340 333
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-122
Chemical type: Peptide from protein
Sequence: MFDSSVLCECYDAGC
Position: 1511-1525
Source molecule (GenBank): BAA09075.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-122
Chemical type: Peptide from protein
Sequence: MFDSSVLCECYDAGC
Position: 1511-1525
Source molecule (GenBank): BAA09075.1
Assay category: TCell
Result: Positive
MHC allele types: 233 244 279 295 340 333
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-122
Chemical type: Peptide from protein
Sequence: MFDSSVLCECYDAGC
Position: 1511-1525
Source molecule (GenBank): BAA09075.1
Assay category: TCell
Result: Positive
MHC allele types: 235 242 288 294 327 352
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-122
Chemical type: Peptide from protein
Sequence: MFDSSVLCECYDAGC
Position: 1511-1525
Source molecule (GenBank): BAA09075.1
Assay category: TCell
Result: Positive
MHC allele types: 233 242 279 295 330
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-122
Chemical type: Peptide from protein
Sequence: MFDSSVLCECYDAGC
Position: 1511-1525
Source molecule (GenBank): BAA09075.1
Assay category: TCell
Result: Positive
MHC allele types: 235 242 288 294 327 352
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-122
Chemical type: Peptide from protein
Sequence: MFDSSVLCECYDAGC
Position: 1511-1525
Source molecule (GenBank): BAA09075.1
Assay category: TCell
Result: Positive
MHC allele types: 233 242 280 283 330 333
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-122
Chemical type: Peptide from protein
Sequence: MFDSSVLCECYDAGC
Position: 1511-1525
Source molecule (GenBank): BAA09075.1
Assay category: TCell
Result: Negative
MHC allele types: 234 249 281 282 334
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV C-32
Chemical type: Peptide from protein
Sequence: TLTCGFADLMGYIPL
Position: 125-139
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
MHC allele types: 233 242 301 281 327 338
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV E1-14
Chemical type: Peptide from protein
Sequence: PTVATRDGKLPTTQL
Position: 244-258
Source molecule (GenBank): AAB02127.1
Assay category: TCell
Result: Positive
MHC allele types: 233 242 301 281 327 338
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV E2-83
Chemical type: Peptide from protein
Sequence: WAIKWEYVVLLFLLL
Position: 712-726
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
MHC allele types: 233 242 301 281 327 338
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV E2-83
Chemical type: Peptide from protein
Sequence: WAIKWEYVVLLFLLL
Position: 712-726
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
MHC allele types: 237 276 281 333 334
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV E1-43
Chemical type: Peptide from protein
Sequence: AYFSMVGNWAKVLVV
Position: 360-374
Source molecule (GenBank): AAB02127.1
Assay category: TCell
Result: Positive
MHC allele types: 233 242 279 295 330
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-91
Chemical type: Peptide from protein
Sequence: GGRHLIFCHSKKKCD
Position: 1387-1401
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
MHC allele types: 242 249 283 300 333 336
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-98
Chemical type: Peptide from protein
Sequence: VAYYRGLDVSVIPTS
Position: 1415-1429
Source molecule (GenBank): AAA86907.1
Assay category: TCell
Result: Positive
MHC allele types: 242 249 283 300 333 336
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-109
Chemical type: Peptide from protein
Sequence: TQTVDFSLDPTFTIE
Position: 1459-1473
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
MHC allele types: 242 249 283 300 333 336
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-118
Chemical type: Peptide from protein
Sequence: KPGIYRFVAPGERPS
Position: 1495-1509
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
MHC allele types: 242 249 283 300 333 336
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-136
Chemical type: Peptide from protein
Sequence: HIDAHFLSQTKQSGE
Position: 1567-1581
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Positive
MHC allele types: 242 249 283 300 333 336
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-140
Chemical type: Peptide from protein
Sequence: FPYLVAYQATVCARA
Position: 1583-1597
Source molecule (GenBank): AAA86907.1
Assay category: TCell
Result: Positive
MHC allele types: 242 249 283 300 333 336
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-140
Chemical type: Peptide from protein
Sequence: FPYLVAYQATVCARA
Position: 1583-1597
Source molecule (GenBank): AAA86907.1
Assay category: TCell
Result: Positive
MHC allele types: 242 249 283 300 333 336
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-116
Chemical type: Peptide from protein
Sequence: RRGRTGRGKPGIYRF
Position: 1487-1501
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
MHC allele types: 233 242 280 283 330 333
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV E2-21
Chemical type: Peptide from protein
Sequence: DFAQGWGPISYANGS
Position: 464-478
Source molecule (GenBank): AAB02127.1
Assay category: TCell
Result: Positive
MHC allele types: 235 276 290 333 237 281 336
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV E2-21
Chemical type: Peptide from protein
Sequence: DFAQGWGPISYANGS
Position: 464-478
Source molecule (GenBank): AAB02127.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV E2-21
Chemical type: Peptide from protein
Sequence: DFAQGWGPISYANGS
Position: 464-478
Source molecule (GenBank): AAB02127.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV E2-21
Chemical type: Peptide from protein
Sequence: DFAQGWGPISYANGS
Position: 464-478
Source molecule (GenBank): AAB02127.1
Assay category: TCell
Result: Negative
MHC allele types: 235 276 290 333 237 281 336
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV C-34
Chemical type: Peptide from protein
Sequence: LMGYIPLVGAPLGGA
Position: 133-147
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
MHC allele types: 235 300 286 336 350
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV C-34
Chemical type: Peptide from protein
Sequence: LMGYIPLVGAPLGGA
Position: 133-147
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
MHC allele types: 235 300 286 336 350
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV C-34
Chemical type: Peptide from protein
Sequence: LMGYIPLVGAPLGGA
Position: 133-147
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV C-34
Chemical type: Peptide from protein
Sequence: LMGYIPLVGAPLGGA
Position: 133-147
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV E1-23
Chemical type: Peptide from protein
Sequence: LCGSVFLVGQLFTFS
Position: 280-294
Source molecule (GenBank): AAB02127.1
Assay category: TCell
Result: Positive
MHC allele types: 235 300 286 336 350
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-12
Chemical type: Peptide from protein
Sequence: ATCINGVCWTVYHGA
Position: 1071-1085
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
MHC allele types: 235 300 286 336 350
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS5A-58
Chemical type: Peptide from protein
Sequence: SSASQLSAPSLKATC
Position: 2201-2215
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
MHC allele types: 235 300 286 336 350
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS5A-87
Chemical type: Peptide from protein
Sequence: PPPRSPPVPPPRKKR
Position: 2317-2331
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Positive
MHC allele types: 235 300 286 336 350
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS5A-105
Chemical type: Peptide from protein
Sequence: PPLEGEPGDPDLSDG
Position: 2389-2403
Source molecule (GenBank): AAA86907.1
Assay category: TCell
Result: Positive
MHC allele types: 235 300 286 336 350
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV E2-76
Chemical type: Peptide from protein
Sequence: ALSTGLIHLHQNIVD
Position: 684-698
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
MHC allele types: 237 276 281 333 334
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-30
Chemical type: Peptide from protein
Sequence: RRRGDSRGSLLSPRP
Position: 1143-1157
Source molecule (GenBank): AAA86907.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS3-30
Chemical type: Peptide from protein
Sequence: RRRGDSRGSLLSPRP
Position: 1143-1157
Source molecule (GenBank): AAA86907.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV E1-33
Chemical type: Peptide from protein
Sequence: WDMMMNWSPTAALVV
Position: 320-334
Source molecule (GenBank): AAA86907.1
Assay category: TCell
Result: Positive
MHC allele types: 233 235 281 290 330 333
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS2-11
Chemical type: Peptide from protein
Sequence: LTRVEAQLHVWVPPL
Position: 850-864
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Positive
MHC allele types: 233 235 281 290 330 333
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV C-33
Chemical type: Peptide from protein
Sequence: GFADLMGYIPLVGAP
Position: 129-143
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Positive
MHC allele types: 236 237 286 290 350 330
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV C-33
Chemical type: Peptide from protein
Sequence: GFADLMGYIPLVGAP
Position: 129-143
Source molecule (GenBank): BAA03375.1
Assay category: TCell
Result: Negative
MHC allele types: 236 237 286 290 350 330
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV E2-39
Chemical type: Peptide from protein
Sequence: VFVLNNTRPPLGNWF
Position: 536-550
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Positive
MHC allele types: 242 239 280 295 350 337
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS5B-53
Chemical type: Peptide from protein
Sequence: KSKKTPMGFSYDTRC
Position: 2629-2643
Source molecule (GenBank): AAB67037.1
Assay category: TCell
Result: Positive
MHC allele types: 242 239 280 295 350 337
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS5B-53
Chemical type: Peptide from protein
Sequence: KSKKTPMGFSYDTRC
Position: 2629-2643
Source molecule (GenBank): AAB67037.1
Assay category: TCell
Result: Positive
MHC allele types: 242 239 280 295 350 337
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV NS5A-59
Chemical type: Peptide from protein
Sequence: QLSAPSLKATCTANH
Position: 2205-2219
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Positive
MHC allele types: 234 249 281 282 334
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV C-9
Chemical type: Peptide from protein
Sequence: GVYLLPRRGPRLGVR
Position: 33-47
Source molecule (GenBank): BAB18806.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo