Reference: Carolina Cruciani; Marco Puthenparampil; Paula Tomas-Ojer; Ivan Jelcic; Maria Jose Docampo; Raquel Planas; Praveena Manogaran; Roland Opfer; Carla Wicki; Markus Reindl; Ilijas Jelcic; Andreas Lutterotti; Roland Martin; Mireia Sospedra. "T-Cell Specificity Influences Disease Heterogeneity in Multiple Sclerosis." Neurology® neuroimmunology & neuroinflammation (2021).

Epitope: GDP-L-fucose synthase 51-65
Chemical type: Peptide from protein
Sequence: TAQTRALFEKVQPTH
Position: 51-65
Source molecule (GenBank): E9PP14.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: GDP-L-fucose synthase 51-65
Chemical type: Peptide from protein
Sequence: TAQTRALFEKVQPTH
Position: 51-65
Source molecule (GenBank): E9PP14.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: GDP-L-fucose synthase 136-150
Chemical type: Peptide from protein
Sequence: PHNSNFGYSYAKRMI
Position: 136-150
Source molecule (GenBank): E9PP14.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: GDP-L-fucose synthase 136-150
Chemical type: Peptide from protein
Sequence: PHNSNFGYSYAKRMI
Position: 136-150
Source molecule (GenBank): E9PP14.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: GDP-L-fucose synthase 161-175
Chemical type: Peptide from protein
Sequence: YGCTFTAVIPTNVFG
Position: 161-175
Source molecule (GenBank): E9PP14.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: GDP-L-fucose synthase 161-175
Chemical type: Peptide from protein
Sequence: YGCTFTAVIPTNVFG
Position: 161-175
Source molecule (GenBank): E9PP14.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: GDP-L-fucose synthase 246-260
Chemical type: Peptide from protein
Sequence: EEDEVSIKEAAEAVV
Position: 246-260
Source molecule (GenBank): Q13630.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: GDP-L-fucose synthase 246-260
Chemical type: Peptide from protein
Sequence: EEDEVSIKEAAEAVV
Position: 246-260
Source molecule (GenBank): Q13630.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: GDP-L-fucose synthase 296-310
Chemical type: Peptide from protein
Sequence: FRFTPFKQAVKETCA
Position: 296-310
Source molecule (GenBank): Q13630.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: GDP-L-fucose synthase 296-310
Chemical type: Peptide from protein
Sequence: FRFTPFKQAVKETCA
Position: 296-310
Source molecule (GenBank): Q13630.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MBP 13-32
Chemical type: Peptide from protein
Sequence: KYLATASTMDHARHGFLPRH
Position: 14-33
Source molecule (GenBank): E9PKX9.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MBP 13-32
Chemical type: Peptide from protein
Sequence: KYLATASTMDHARHGFLPRH
Position: 14-33
Source molecule (GenBank): E9PKX9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MBP 83-99
Chemical type: Peptide from protein
Sequence: ENPVVHFFKNIVTPRT
Position: 217-232
Source molecule (GenBank): J3QQK6
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MBP 83-99
Chemical type: Peptide from protein
Sequence: ENPVVHFFKNIVTPRT
Position: 217-232
Source molecule (GenBank): J3QQK6
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MBP 111-129
Chemical type: Peptide from protein
Sequence: LSRFSWGAEGQRPGFGYGG
Position: 90-108
Source molecule (GenBank): E9PJ72.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MBP 111-129
Chemical type: Peptide from protein
Sequence: LSRFSWGAEGQRPGFGYGG
Position: 90-108
Source molecule (GenBank): E9PJ72.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MBP 146-170
Chemical type: Peptide from protein
Sequence: AQGTLSKIFKLGGRDSRSGSPMARR
Position: 125-149
Source molecule (GenBank): E9PJ72.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MBP 146-170
Chemical type: Peptide from protein
Sequence: AQGTLSKIFKLGGRDSRSGSPMARR
Position: 125-149
Source molecule (GenBank): E9PJ72.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MOG 1-20
Chemical type: Peptide from protein
Sequence: GQFRVIGPRHPIRALVGDEV
Position: 30-49
Source molecule (GenBank): CAQ06612.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MOG 1-20
Chemical type: Peptide from protein
Sequence: GQFRVIGPRHPIRALVGDEV
Position: 30-49
Source molecule (GenBank): CAQ06612.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): CAQ06612.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): CAQ06612.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): CAQ06612.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): CAQ06612.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): CAQ06612.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): CAQ06612.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): CAQ06612.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): CAQ06612.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): CAQ06612.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): CAQ06612.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): CAQ06612.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): CAQ06612.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): CAQ06612.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRPPFSRVVHLYRNGK
Position: 64-84
Source molecule (GenBank): CAQ06612.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: PLP 139-154
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKFVGI
Position: 140-155
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo

Epitope: PLP 139-154
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKFVGI
Position: 140-155
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Direct Ex Vivo