Reference: Andreas Walker; Tatjana Schwarz; Janine Brinkmann-Paulukat; Karin Wisskirchen; Christopher Menne; Elahe Salimi Alizei; Helenie Kefalakes; Martin Theissen; Daniel Hoffmann; Julian Schulze Zur Wiesch; Mala K Maini; Markus Cornberg; Anke Rm Kraft; Verena Keitel; Hans H Bock; Peter A Horn; Robert Thimme; Heiner Wedemeyer; Falko M Heinemann; Tom Luedde; Christoph Neumann-Haefelin; Ulrike Protzer; Jörg Timm. "Immune escape pathways from the HBV core<sub>18-27</sub> CD8 T cell response are driven by individual HLA class I alleles." Frontiers in immunology (2022).

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 18-27
Source molecule (GenBank): AAU01933.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant F7Y
Chemical type: Peptide from protein
Sequence: FLPSDFYPSV
Position: 18-27
Source molecule (GenBank): AJT55251.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant F7Y
Chemical type: Peptide from protein
Sequence: FLPSDFYPSV
Position: 18-27
Source molecule (GenBank): AJT55251.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant V10I
Chemical type: Peptide from protein
Sequence: FLPSDFFPSI
Position: 18-27
Source molecule (GenBank): Q9QAC5.1
Assay category: TCell
Result: Positive
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant V10I
Chemical type: Peptide from protein
Sequence: FLPSDFFPSI
Position: 18-27
Source molecule (GenBank): Q9QAC5.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant V10A
Chemical type: Peptide from protein
Sequence: FLPSDFFPSA
Position: 18-27
Source molecule (GenBank): ACF58604.1
Assay category: TCell
Result: Positive
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant V10A
Chemical type: Peptide from protein
Sequence: FLPSDFFPSA
Position: 18-27
Source molecule (GenBank): ACF58604.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant S4A
Chemical type: Peptide from protein
Sequence: FLPADFFPSV
Position: 18-27
Source molecule (GenBank): ABE97049.1
Assay category: TCell
Result: Positive
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant S4A
Chemical type: Peptide from protein
Sequence: FLPADFFPSV
Position: 18-27
Source molecule (GenBank): ABE97049.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant S4P
Chemical type: Peptide from protein
Sequence: FLPPDFFPSV
Position: 18-27
Source molecule (GenBank): AAR19324.1
Assay category: TCell
Result: Positive
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant S4P
Chemical type: Peptide from protein
Sequence: FLPPDFFPSV
Position: 18-27
Source molecule (GenBank): AAR19324.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant S4T
Chemical type: Peptide from protein
Sequence: FLPTDFFPSV
Position: 18-27
Source molecule (GenBank): ACF58606.1
Assay category: TCell
Result: Positive
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant S4T
Chemical type: Peptide from protein
Sequence: FLPTDFFPSV
Position: 18-27
Source molecule (GenBank): ACF58606.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant S4H
Chemical type: Peptide from protein
Sequence: FLPHDFFPSV
Position: 18-27
Source molecule (GenBank): ASF62045.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant S4H
Chemical type: Peptide from protein
Sequence: FLPHDFFPSV
Position: 18-27
Source molecule (GenBank): ASF62045.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant S4H/V10I
Chemical type: Peptide from protein
Sequence: FLPHDFFPSI
Position: 18-27
Source molecule (GenBank): AJT55368.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant S4H/V10I
Chemical type: Peptide from protein
Sequence: FLPHDFFPSI
Position: 18-27
Source molecule (GenBank): AJT55368.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant S4H/F7Y
Chemical type: Peptide from protein
Sequence: FLPHDFYPSV
Position: 18-27
Source molecule (GenBank): ASF62034.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant S4H/F7Y
Chemical type: Peptide from protein
Sequence: FLPHDFYPSV
Position: 18-27
Source molecule (GenBank): ASF62034.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant S4Q/F7Y
Chemical type: Peptide from protein
Sequence: FLPQDFYPSV
Position: 18-27
Source molecule (GenBank): ACP20525.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 195 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 18-27 variant S4Q/F7Y
Chemical type: Peptide from protein
Sequence: FLPQDFYPSV
Position: 18-27
Source molecule (GenBank): ACP20525.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated