Reference: Alessia Muzi; Roberto Arriga; Giovanni Bulfaro; Francesca Fata; Antonella Costanzo; Valerio Chiarini; Manuela Cappelletti; Fabiana Fosca Ferrara; Federica Bucci; Linda Celeste Montemiglio; Carmelinda Savino; Emanuele Marra; Gennaro Ciliberto; Luigi Aurisicchio; Beatrice Vallone; Giuseppe Roscilli. "Novel Humanized Anti-HER3 Antibodies: Structural Characterization and Therapeutic Activity." Antibodies (Basel, Switzerland) (2025).

Epitope: Epitope of TK-hu A3 (H1L1) Fab on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: R103, T204, A211, P212, Q213, C218, F219, G220, P221, N222, P223, N224, Q225, C235, S236, G237, P238, D242
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.8

Epitope: Epitope of TK-hu A3 (H1L1) Fab on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: R103, T204, A211, P212, Q213, C218, F219, G220, P221, N222, P223, N224, Q225, C235, S236, G237, P238, D242
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.81

Epitope: Epitope of TK-hu A3 (H1L1) Fab on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: R103, T204, A211, P212, Q213, C218, F219, G220, P221, N222, P223, N224, Q225, C235, S236, G237, P238, D242
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive
Quantitative measurement: 62400.0

Epitope: Epitope of TK-hu A3 (H1L1) Fab on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: R103, T204, A211, P212, Q213, C218, F219, G220, P221, N222, P223, N224, Q225, C235, S236, G237, P238, D242
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000113

Epitope: Epitope of TK-hu A3 (H1L1) Fab on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: R103, T204, A211, P212, Q213, C218, F219, G220, P221, N222, P223, N224, Q225, C235, S236, G237, P238, D242
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: Epitope of TK-hu A3 (H1L1) Fab on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: R103, T204, A211, P212, Q213, C218, F219, G220, P221, N222, P223, N224, Q225, C235, S236, G237, P238, D242
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: Epitope of TK-hu A3 (H1L1) Fab on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: R103, T204, A211, P212, Q213, C218, F219, G220, P221, N222, P223, N224, Q225, C235, S236, G237, P238, D242
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: Epitope of TK-hu A3 (H1L1) Fab on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: R103, T204, A211, P212, Q213, C218, F219, G220, P221, N222, P223, N224, Q225, C235, S236, G237, P238, D242
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: Epitope of TK-hu A3 (H1L1) Fab on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: R103, T204, A211, P212, Q213, C218, F219, G220, P221, N222, P223, N224, Q225, C235, S236, G237, P238, D242
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: Epitope of TK-hu A3 (H1L1) Fab on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: R103, T204, A211, P212, Q213, C218, F219, G220, P221, N222, P223, N224, Q225, C235, S236, G237, P238, D242
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: Epitope of TK-hu A3 (H1L1) Fab on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: R103, T204, A211, P212, Q213, C218, F219, G220, P221, N222, P223, N224, Q225, C235, S236, G237, P238, D242
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: Epitope of TK-hu A3 (H2L1) mAb on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: Q213, C214, N215, G216, H217, C218, F219, G220, P221, N222, P223, N224, Q225, C226, C227, Q261, P262, L263, V264, Y265, N266, K267, L268, T269, F270, Q271, L272, E273, P274, N275
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: Epitope of TK-hu A3 (H2L1) mAb on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: Q213, C214, N215, G216, H217, C218, F219, G220, P221, N222, P223, N224, Q225, C226, C227, Q261, P262, L263, V264, Y265, N266, K267, L268, T269, F270, Q271, L272, E273, P274, N275
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: Epitope of TK-hu A3 (H2L1) mAb on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: Q213, C214, N215, G216, H217, C218, F219, G220, P221, N222, P223, N224, Q225, C226, C227, Q261, P262, L263, V264, Y265, N266, K267, L268, T269, F270, Q271, L272, E273, P274, N275
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: Epitope of TK-hu A3 (H2L1) mAb on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: Q213, C214, N215, G216, H217, C218, F219, G220, P221, N222, P223, N224, Q225, C226, C227, Q261, P262, L263, V264, Y265, N266, K267, L268, T269, F270, Q271, L272, E273, P274, N275
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: Epitope of TK-hu A3 (H2L1) mAb on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: Q213, C214, N215, G216, H217, C218, F219, G220, P221, N222, P223, N224, Q225, C226, C227, Q261, P262, L263, V264, Y265, N266, K267, L268, T269, F270, Q271, L272, E273, P274, N275
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: Epitope of TK-hu A3 (H2L1) mAb on HER-3
Chemical type: Discontinuous protein residues
Discontinuous residues: Q213, C214, N215, G216, H217, C218, F219, G220, P221, N222, P223, N224, Q225, C226, C227, Q261, P262, L263, V264, Y265, N266, K267, L268, T269, F270, Q271, L272, E273, P274, N275
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: HER3 (213-227)
Chemical type: Peptide from protein
Sequence: QCNGHCFGPNPNQCC
Position: 213-227
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.13

Epitope: HER3 (213-227)
Chemical type: Peptide from protein
Sequence: QCNGHCFGPNPNQCC
Position: 213-227
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive
Quantitative measurement: 38300.0

Epitope: HER3 (213-227)
Chemical type: Peptide from protein
Sequence: QCNGHCFGPNPNQCC
Position: 213-227
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000817

Epitope: HER3 (213-227)
Chemical type: Peptide from protein
Sequence: QCNGHCFGPNPNQCC
Position: 213-227
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: HER3 (213-227)
Chemical type: Peptide from protein
Sequence: QCNGHCFGPNPNQCC
Position: 213-227
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: HER3 (213-227)
Chemical type: Peptide from protein
Sequence: QCNGHCFGPNPNQCC
Position: 213-227
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: HER3 (213-227)
Chemical type: Peptide from protein
Sequence: QCNGHCFGPNPNQCC
Position: 213-227
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive

Epitope: HER3 (213-227)
Chemical type: Peptide from protein
Sequence: QCNGHCFGPNPNQCC
Position: 213-227
Source molecule (GenBank): P21860.1
Assay category: BCell
Result: Positive