Reference: Salvatore G De-Simone; Paloma Napoleão-Pego; Luiz A L Teixeira-Pinto; Jonathas D L Santos; Thatiane S De-Simone; Anibal R Melgarejo; Aniesse S Aguiar; Daniela P Marchi-Salvador. "Linear B-cell epitopes in BthTX-1, BthTX-II and BthA-1, phospholipase A₂'s from Bothrops jararacussu snake venom, recognized by therapeutically neutralizing commercial horse antivenom." Toxicon : official journal of the International Society on Toxinology (2013).

Epitope: A1
Chemical type: Peptide from protein
Sequence: SLFELGKMILQETG
Position: 17-30
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A1
Chemical type: Peptide from protein
Sequence: SLFELGKMILQETG
Position: 17-30
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A2
Chemical type: Peptide from protein
Sequence: GKMILQETGKNPAK
Position: 22-35
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A3
Chemical type: Peptide from protein
Sequence: QETGKNPAKSYGAY
Position: 27-40
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: BthTX-I (27-30)
Chemical type: Peptide from protein
Sequence: CNCG
Position: 42-45
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Positive

Epitope: BthTX-I (27-30)
Chemical type: Peptide from protein
Sequence: CNCG
Position: 42-45
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Positive

Epitope: A7
Chemical type: Peptide from protein
Sequence: LGRGKPKDATDRCC
Position: 47-60
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A7
Chemical type: Peptide from protein
Sequence: LGRGKPKDATDRCC
Position: 47-60
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A8
Chemical type: Peptide from protein
Sequence: PKDATDRCCYVHKC
Position: 52-65
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A8
Chemical type: Peptide from protein
Sequence: PKDATDRCCYVHKC
Position: 52-65
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A9
Chemical type: Peptide from protein
Sequence: DRCCYVHKCCYKKL
Position: 57-70
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A9
Chemical type: Peptide from protein
Sequence: DRCCYVHKCCYKKL
Position: 57-70
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A10
Chemical type: Peptide from protein
Sequence: VHKCCYKKLTGCDP
Position: 62-75
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A10
Chemical type: Peptide from protein
Sequence: VHKCCYKKLTGCDP
Position: 62-75
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: BthTX-I (59-73)
Chemical type: Peptide from protein
Sequence: GCDPKKDRY
Position: 72-80
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Positive

Epitope: BthTX-I (59-73)
Chemical type: Peptide from protein
Sequence: GCDPKKDRY
Position: 72-80
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Positive

Epitope: A12
Chemical type: Peptide from protein
Sequence: GCDPKKDRYSYSWK
Position: 72-85
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A13
Chemical type: Peptide from protein
Sequence: KDRYSYSWKDKTIV
Position: 77-90
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A13
Chemical type: Peptide from protein
Sequence: KDRYSYSWKDKTIV
Position: 77-90
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A14
Chemical type: Peptide from protein
Sequence: YSWKDKTIVCGENN
Position: 82-95
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A15
Chemical type: Peptide from protein
Sequence: KTIVCGENNPCLKE
Position: 87-100
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A16
Chemical type: Peptide from protein
Sequence: GENNPCLKELCECD
Position: 92-105
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A16
Chemical type: Peptide from protein
Sequence: GENNPCLKELCECD
Position: 92-105
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A17
Chemical type: Peptide from protein
Sequence: CLKELCECDKAVAI
Position: 97-110
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A17
Chemical type: Peptide from protein
Sequence: CLKELCECDKAVAI
Position: 97-110
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A18
Chemical type: Peptide from protein
Sequence: CECDKAVAICLREN
Position: 102-115
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A18
Chemical type: Peptide from protein
Sequence: CECDKAVAICLREN
Position: 102-115
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A19
Chemical type: Peptide from protein
Sequence: AVAICLRENLGTYN
Position: 107-120
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A19
Chemical type: Peptide from protein
Sequence: AVAICLRENLGTYN
Position: 107-120
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A21
Chemical type: Peptide from protein
Sequence: GTYNKKYRYHLKPF
Position: 117-130
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A21
Chemical type: Peptide from protein
Sequence: GTYNKKYRYHLKPF
Position: 117-130
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: BthA-I (116-130)
Chemical type: Peptide from protein
Sequence: KYRYHLKPFCKKAD
Position: 122-135
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: BthA-I (116-130)
Chemical type: Peptide from protein
Sequence: KYRYHLKPFCKKAD
Position: 122-135
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Positive

Epitope: A23
Chemical type: Peptide from protein
Sequence: RYHLKPFCKKADPC
Position: 124-137
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A23
Chemical type: Peptide from protein
Sequence: RYHLKPFCKKADPC
Position: 124-137
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Negative

Epitope: A24
Chemical type: Peptide from protein
Sequence: DLWQFGQMILKETG
Position: 17-30
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: A24
Chemical type: Peptide from protein
Sequence: DLWQFGQMILKETG
Position: 17-30
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B1
Chemical type: Peptide from protein
Sequence: GQMILKETGKLPFP
Position: 22-35
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B1
Chemical type: Peptide from protein
Sequence: GQMILKETGKLPFP
Position: 22-35
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: BthTX-II (17-25)
Chemical type: Peptide from protein
Sequence: LPFPYYTTY
Position: 32-40
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Positive

Epitope: BthTX-II (17-25)
Chemical type: Peptide from protein
Sequence: LPFPYYTTY
Position: 32-40
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Positive

Epitope: B4
Chemical type: Peptide from protein
Sequence: YTTYGCYCGWGGQG
Position: 37-50
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B4
Chemical type: Peptide from protein
Sequence: YTTYGCYCGWGGQG
Position: 37-50
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B5
Chemical type: Peptide from protein
Sequence: CYCGWGGQGQPKDA
Position: 42-55
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B5
Chemical type: Peptide from protein
Sequence: CYCGWGGQGQPKDA
Position: 42-55
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: BthTX-II (37-45)
Chemical type: Peptide from protein
Sequence: PKDATDRCC
Position: 52-60
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Positive

Epitope: BthTX-II (37-45)
Chemical type: Peptide from protein
Sequence: PKDATDRCC
Position: 52-60
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Positive

Epitope: B11
Chemical type: Peptide from protein
Sequence: NCKPKTDRYSYSRE
Position: 72-85
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Positive

Epitope: B12
Chemical type: Peptide from protein
Sequence: TDRYSYSRENGVII
Position: 77-90
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: BthTX-II (79-89)
Chemical type: Peptide from protein
Sequence: GVIICGEGT
Position: 87-95
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Positive

Epitope: BthTX-II (79-89)
Chemical type: Peptide from protein
Sequence: GVIICGEGT
Position: 87-95
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Positive

Epitope: B14
Chemical type: Peptide from protein
Sequence: GVIICGEGTPCEKQ
Position: 87-100
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B15
Chemical type: Peptide from protein
Sequence: GEGTPCEKQICECD
Position: 92-105
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B15
Chemical type: Peptide from protein
Sequence: GEGTPCEKQICECD
Position: 92-105
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B16
Chemical type: Peptide from protein
Sequence: CEKQICECDKAAAV
Position: 97-110
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B16
Chemical type: Peptide from protein
Sequence: CEKQICECDKAAAV
Position: 97-110
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B18
Chemical type: Peptide from protein
Sequence: AAAVCFRENLRTYK
Position: 107-120
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B18
Chemical type: Peptide from protein
Sequence: AAAVCFRENLRTYK
Position: 107-120
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B19
Chemical type: Peptide from protein
Sequence: FRENLRTYKKRYMA
Position: 112-125
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B19
Chemical type: Peptide from protein
Sequence: FRENLRTYKKRYMA
Position: 112-125
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B20
Chemical type: Peptide from protein
Sequence: RTYKKRYMAYPDVL
Position: 117-130
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B20
Chemical type: Peptide from protein
Sequence: RTYKKRYMAYPDVL
Position: 117-130
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B21
Chemical type: Peptide from protein
Sequence: RYMAYPDVLCKKPA
Position: 122-135
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B21
Chemical type: Peptide from protein
Sequence: RYMAYPDVLCKKPA
Position: 122-135
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B22
Chemical type: Peptide from protein
Sequence: AYPDVLCKKPAEKC
Position: 125-138
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B22
Chemical type: Peptide from protein
Sequence: AYPDVLCKKPAEKC
Position: 125-138
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Negative

Epitope: B23
Chemical type: Peptide from protein
Sequence: SLWQFGKMINYVMG
Position: 17-30
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: B23
Chemical type: Peptide from protein
Sequence: SLWQFGKMINYVMG
Position: 17-30
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: B24
Chemical type: Peptide from protein
Sequence: GKMINYVMGESGVL
Position: 22-35
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: B24
Chemical type: Peptide from protein
Sequence: GKMINYVMGESGVL
Position: 22-35
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: BthA-I (17-25)
Chemical type: Peptide from protein
Sequence: SGVLQYLSY
Position: 32-40
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Positive

Epitope: BthA-I (17-25)
Chemical type: Peptide from protein
Sequence: SGVLQYLSY
Position: 32-40
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Positive

Epitope: C3
Chemical type: Peptide from protein
Sequence: YLSYGCYCGLGGQG
Position: 37-50
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C3
Chemical type: Peptide from protein
Sequence: YLSYGCYCGLGGQG
Position: 37-50
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C4
Chemical type: Peptide from protein
Sequence: CYCGLGGQGQPTDA
Position: 42-55
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C4
Chemical type: Peptide from protein
Sequence: CYCGLGGQGQPTDA
Position: 42-55
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C5
Chemical type: Peptide from protein
Sequence: GGQGQPTDATDRCC
Position: 47-60
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C5
Chemical type: Peptide from protein
Sequence: GGQGQPTDATDRCC
Position: 47-60
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C6
Chemical type: Peptide from protein
Sequence: PTDATDRCCFVHDC
Position: 52-65
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C6
Chemical type: Peptide from protein
Sequence: PTDATDRCCFVHDC
Position: 52-65
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C7
Chemical type: Peptide from protein
Sequence: DRCCFVHDCCYGKV
Position: 57-70
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C7
Chemical type: Peptide from protein
Sequence: DRCCFVHDCCYGKV
Position: 57-70
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C8
Chemical type: Peptide from protein
Sequence: VHDCCYGKVTGCDP
Position: 62-75
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C8
Chemical type: Peptide from protein
Sequence: VHDCCYGKVTGCDP
Position: 62-75
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: BthA-I (52-73)
Chemical type: Peptide from protein
Sequence: YGKVTGCDPKIDSY
Position: 67-80
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Positive

Epitope: BthA-I (52-73)
Chemical type: Peptide from protein
Sequence: YGKVTGCDPKIDSY
Position: 67-80
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C10
Chemical type: Peptide from protein
Sequence: GCDPKIDSYTYSKK
Position: 72-85
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C10
Chemical type: Peptide from protein
Sequence: GCDPKIDSYTYSKK
Position: 72-85
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C12
Chemical type: Peptide from protein
Sequence: YSKKNGDVVCGGDD
Position: 82-95
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C12
Chemical type: Peptide from protein
Sequence: YSKKNGDVVCGGDD
Position: 82-95
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C13
Chemical type: Peptide from protein
Sequence: GDVVCGGDDPCKKQ
Position: 87-100
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C13
Chemical type: Peptide from protein
Sequence: GDVVCGGDDPCKKQ
Position: 87-100
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C14
Chemical type: Peptide from protein
Sequence: GGDDPCKKQICECD
Position: 92-105
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C14
Chemical type: Peptide from protein
Sequence: GGDDPCKKQICECD
Position: 92-105
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C15
Chemical type: Peptide from protein
Sequence: CKKQICECDRVATT
Position: 97-110
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C15
Chemical type: Peptide from protein
Sequence: CKKQICECDRVATT
Position: 97-110
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C16
Chemical type: Peptide from protein
Sequence: CECDRVATTCFRDN
Position: 102-115
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C16
Chemical type: Peptide from protein
Sequence: CECDRVATTCFRDN
Position: 102-115
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C17
Chemical type: Peptide from protein
Sequence: VATTCFRDNKDTYD
Position: 107-120
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C17
Chemical type: Peptide from protein
Sequence: VATTCFRDNKDTYD
Position: 107-120
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: BthA-I (106-119)
Chemical type: Peptide from protein
Sequence: FRDNKDTYDIKYWF
Position: 112-125
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: BthA-I (106-119)
Chemical type: Peptide from protein
Sequence: FRDNKDTYDIKYWF
Position: 112-125
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Positive

Epitope: C19
Chemical type: Peptide from protein
Sequence: DTYDIKYWFYGAKN
Position: 117-130
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C19
Chemical type: Peptide from protein
Sequence: DTYDIKYWFYGAKN
Position: 117-130
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C20
Chemical type: Peptide from protein
Sequence: KYWFYGAKNCQEKS
Position: 122-135
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C20
Chemical type: Peptide from protein
Sequence: KYWFYGAKNCQEKS
Position: 122-135
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C21
Chemical type: Peptide from protein
Sequence: FYGAKNCQEKSEPC
Position: 125-138
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: C21
Chemical type: Peptide from protein
Sequence: FYGAKNCQEKSEPC
Position: 125-138
Source molecule (GenBank): Q8AXY1.1
Assay category: BCell
Result: Negative

Epitope: BthTX-1 (11-20)
Chemical type: Peptide from protein
Sequence: QETGKNPAK
Position: 27-35
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Positive

Epitope: BthTX-II (69-77)
Chemical type: Peptide from protein
Sequence: TDRYSYSRE
Position: 77-85
Source molecule (GenBank): P45881.1
Assay category: BCell
Result: Positive

Epitope: BthTX-1 (84-89)
Chemical type: Peptide from protein
Sequence: CGENN
Position: 91-95
Source molecule (GenBank): Q90249.3
Assay category: BCell
Result: Positive