Reference: Kai Schulze; Eva Medina; Gursharan S Chhatwal; Carlos A Guzmán. "Identification of B- and T-cell epitopes within the fibronectin-binding domain of the SfbI protein of Streptococcus pyogenes." Infection and immunity (2003).

Epitope: Peptide 1.373-388
Chemical type: Peptide from protein
Sequence: VETEDTKEPGVLMGGQ
Position: 422-437
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 1.373-388
Chemical type: Peptide from protein
Sequence: VETEDTKEPGVLMGGQ
Position: 422-437
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 1.373-388
Chemical type: Peptide from protein
Sequence: VETEDTKEPGVLMGGQ
Position: 422-437
Source molecule (GenBank): CAA48133.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 3.381-396
Chemical type: Peptide from protein
Sequence: PGVLMGGQSESVEFTK
Position: 430-445
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 3.381-396
Chemical type: Peptide from protein
Sequence: PGVLMGGQSESVEFTK
Position: 430-445
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 3.381-396
Chemical type: Peptide from protein
Sequence: PGVLMGGQSESVEFTK
Position: 430-445
Source molecule (GenBank): CAA48133.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 4.385-400
Chemical type: Peptide from protein
Sequence: MGGQSESVEFTKDTQT
Position: 434-449
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 4.385-400
Chemical type: Peptide from protein
Sequence: MGGQSESVEFTKDTQT
Position: 434-449
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 4.385-400
Chemical type: Peptide from protein
Sequence: MGGQSESVEFTKDTQT
Position: 434-449
Source molecule (GenBank): CAA48133.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 5.389-404
Chemical type: Peptide from protein
Sequence: SESVEFTKDTQTGMSG
Position: 438-453
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 5.389-404
Chemical type: Peptide from protein
Sequence: SESVEFTKDTQTGMSG
Position: 438-453
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 5.389-404
Chemical type: Peptide from protein
Sequence: SESVEFTKDTQTGMSG
Position: 438-453
Source molecule (GenBank): CAA48133.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 6.393-408
Chemical type: Peptide from protein
Sequence: EFTKDTQTGMAGQTTP
Assay category: BCell
Result: Negative

Epitope: Peptide 6.393-408
Chemical type: Peptide from protein
Sequence: EFTKDTQTGMAGQTTP
Assay category: BCell
Result: Negative

Epitope: Peptide 6.393-408
Chemical type: Peptide from protein
Sequence: EFTKDTQTGMAGQTTP
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 7.397-412
Chemical type: Peptide from protein
Sequence: DTQTGMAGQTTPQVET
Assay category: BCell
Result: Positive

Epitope: Peptide 7.397-412
Chemical type: Peptide from protein
Sequence: DTQTGMAGQTTPQVET
Assay category: BCell
Result: Negative

Epitope: Peptide 7.397-412
Chemical type: Peptide from protein
Sequence: DTQTGMAGQTTPQVET
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 9.405-420
Chemical type: Peptide from protein
Sequence: QTTPQVETEDTKEPGV
Position: 454-469
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 9.405-420
Chemical type: Peptide from protein
Sequence: QTTPQVETEDTKEPGV
Position: 454-469
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 9.405-420
Chemical type: Peptide from protein
Sequence: QTTPQVETEDTKEPGV
Position: 454-469
Source molecule (GenBank): CAA48133.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 10.409-424
Chemical type: Peptide from protein
Sequence: QVETEDTKEPGVLMGG
Position: 458-473
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 10.409-424
Chemical type: Peptide from protein
Sequence: QVETEDTKEPGVLMGG
Position: 458-473
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 10.409-424
Chemical type: Peptide from protein
Sequence: QVETEDTKEPGVLMGG
Position: 458-473
Source molecule (GenBank): CAA48133.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 11.413-428
Chemical type: Peptide from protein
Sequence: EDTKEPGVLMGGQSES
Position: 425-440
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 11.413-428
Chemical type: Peptide from protein
Sequence: EDTKEPGVLMGGQSES
Position: 425-440
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 11.413-428
Chemical type: Peptide from protein
Sequence: EDTKEPGVLMGGQSES
Position: 425-440
Source molecule (GenBank): CAA48133.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 12.417-432
Chemical type: Peptide from protein
Sequence: EPGVLMGGQSESVEFT
Position: 429-444
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 12.417-432
Chemical type: Peptide from protein
Sequence: EPGVLMGGQSESVEFT
Position: 429-444
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 12.417-432
Chemical type: Peptide from protein
Sequence: EPGVLMGGQSESVEFT
Position: 429-444
Source molecule (GenBank): CAA48133.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 13.421-436
Chemical type: Peptide from protein
Sequence: LMGGQSESVEFTKDTQ
Position: 433-448
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 13.421-436
Chemical type: Peptide from protein
Sequence: LMGGQSESVEFTKDTQ
Position: 433-448
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 13.421-436
Chemical type: Peptide from protein
Sequence: LMGGQSESVEFTKDTQ
Position: 433-448
Source molecule (GenBank): CAA48133.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 14.425-440
Chemical type: Peptide from protein
Sequence: QSESVEFTKDTQTGMS
Position: 437-452
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 14.425-440
Chemical type: Peptide from protein
Sequence: QSESVEFTKDTQTGMS
Position: 437-452
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 14.425-440
Chemical type: Peptide from protein
Sequence: QSESVEFTKDTQTGMS
Position: 437-452
Source molecule (GenBank): CAA48133.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 1.361-375
Chemical type: Peptide from protein
Sequence: KLPNETGFSGNMVET
Position: 410-424
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 2.364-378
Chemical type: Peptide from protein
Sequence: NETGFSGNMVETEDT
Position: 413-427
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 3.367-381
Chemical type: Peptide from protein
Sequence: GFSGNMVETEDTKEP
Position: 416-430
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 4.370-384
Chemical type: Peptide from protein
Sequence: GNMVETEDTKEPGVL
Position: 419-433
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 5.373-387
Chemical type: Peptide from protein
Sequence: VETEDTKEPGVLMGG
Position: 422-436
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 6.376-390
Chemical type: Peptide from protein
Sequence: EDTKEPGVLMGGQSE
Position: 425-439
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 7.379-393
Chemical type: Peptide from protein
Sequence: KEPGVLMGGQSESVE
Position: 428-442
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 8.382-396
Chemical type: Peptide from protein
Sequence: GVLMGGQSESVEFTK
Position: 431-445
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 10.388-402
Chemical type: Peptide from protein
Sequence: QSESVEFTKDTQTGM
Position: 437-451
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 11.391-405
Chemical type: Peptide from protein
Sequence: SVEFTKDTQTGMSGQ
Position: 440-454
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 12.394-408
Chemical type: Peptide from protein
Sequence: FTKDTQTGMSGQTTP
Position: 443-457
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 13.397-411
Chemical type: Peptide from protein
Sequence: DTQTGMSGQTTPQVE
Position: 446-460
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 14.400-414
Chemical type: Peptide from protein
Sequence: TGMSGQTTPQVETED
Position: 449-463
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 15.403-417
Chemical type: Peptide from protein
Sequence: SGQTTPQVETEDTKE
Position: 452-466
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 16.406-420
Chemical type: Peptide from protein
Sequence: TTPQVETEDTKEPGV
Position: 455-469
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 18.412-426
Chemical type: Peptide from protein
Sequence: TEDTKEPGVLMGGQS
Position: 424-438
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 19.415-429
Chemical type: Peptide from protein
Sequence: TKEPGVLMGGQSESV
Position: 427-441
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 20.418-432
Chemical type: Peptide from protein
Sequence: PGVLMGGQSESVEFT
Position: 430-444
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 21.421-435
Chemical type: Peptide from protein
Sequence: LMGGQSESVEFTKDT
Position: 433-447
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 22.424-438
Chemical type: Peptide from protein
Sequence: GQSESVEFTKDTQTG
Position: 436-450
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 23.427-441
Chemical type: Peptide from protein
Sequence: ESVEFTKDTQTGMSG
Position: 439-453
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 24.430-444
Chemical type: Peptide from protein
Sequence: EFTKDTQTGMSGQTA
Position: 479-493
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 25.433-447
Chemical type: Peptide from protein
Sequence: KDTQTGMSGQTASQV
Position: 482-496
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 26.436-450
Chemical type: Peptide from protein
Sequence: QTGMSGQTASQVETE
Position: 485-499
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 27.439-453
Chemical type: Peptide from protein
Sequence: MSGQTASQVETEDTK
Position: 488-502
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 28.442-456
Chemical type: Peptide from protein
Sequence: QTASQVETEDTKEPG
Position: 491-505
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 29.445-459
Chemical type: Peptide from protein
Sequence: SQVETEDTKEPGVLM
Position: 494-508
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 31.451-465
Chemical type: Peptide from protein
Sequence: DTKEPGVLMGGQSES
Position: 426-440
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 32.454-468
Chemical type: Peptide from protein
Sequence: EPGVLMGGQSESVEF
Position: 429-443
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 34.460-474
Chemical type: Peptide from protein
Sequence: GGQSESVEFTKDTQT
Position: 435-449
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 35.463-477
Chemical type: Peptide from protein
Sequence: SESVEFTKDTQTGMS
Position: 438-452
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 36.466-480
Chemical type: Peptide from protein
Sequence: VEFTKDTQTGMSGQT
Position: 441-455
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 37.469-483
Chemical type: Peptide from protein
Sequence: TKDTQTGMSGQTTPQ
Position: 444-458
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 38.472-486
Chemical type: Peptide from protein
Sequence: TQTGMSGQTTPQVET
Position: 447-461
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 39.475-489
Chemical type: Peptide from protein
Sequence: GMSGQTTPQVETEDT
Position: 450-464
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 40.478-492
Chemical type: Peptide from protein
Sequence: GQTTPQVETEDTKEP
Position: 453-467
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 41.481-495
Chemical type: Peptide from protein
Sequence: TPQVETEDTKEPGVL
Position: 456-470
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 42.484-498
Chemical type: Peptide from protein
Sequence: VETEDTKEPGVLMGG
Position: 422-436
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 43.487-501
Chemical type: Peptide from protein
Sequence: EDTKEPGVLMGGQSE
Position: 425-439
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 44.490-504
Chemical type: Peptide from protein
Sequence: KEPGVLMGGQSESVE
Position: 428-442
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 45.493-507
Chemical type: Peptide from protein
Sequence: GVLMGGQSESVEFTK
Position: 431-445
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 47.499-513
Chemical type: Peptide from protein
Sequence: QSESVEFTKDTQTGM
Position: 437-451
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 48.502-516
Chemical type: Peptide from protein
Sequence: SVEFTKDTQTGMSGF
Position: 551-565
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 49.505-519
Chemical type: Peptide from protein
Sequence: FTKDTQTGMSGFSET
Position: 554-568
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 50.508-522
Chemical type: Peptide from protein
Sequence: DTQTGMSGFSETVTI
Position: 557-571
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Negative

Epitope: Peptide 51.511-525
Chemical type: Peptide from protein
Sequence: TGMSGFSETVTIVED
Position: 560-574
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive

Epitope: Peptide 52.514-528
Chemical type: Peptide from protein
Sequence: SGFSETVTIVEDTRP
Position: 563-577
Source molecule (GenBank): CAA48133.1
Assay category: BCell
Result: Positive