Reference: Paola Bonaventura; Vincent Alcazer; Virginie Mutez; Laurie Tonon; Juliette Martin; Nicolas Chuvin; Emilie Michel; Rasha E Boulos; Yann Estornes; Jenny Valladeau-Guilemond; Alain Viari; Qing Wang; Christophe Caux; Stéphane Depil. "Identification of shared tumor epitopes from endogenous retroviruses inducing high-avidity cytotoxic T cells for cancer immunotherapy." Science advances (2022).

Epitope: P1
Chemical type: Peptide from protein
Sequence: FLQFKTWWI
Position: 363-371
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: P1
Chemical type: Peptide from protein
Sequence: FLQFKTWWI
Position: 363-371
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: P1
Chemical type: Peptide from protein
Sequence: FLQFKTWWI
Position: 363-371
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: P1
Chemical type: Peptide from protein
Sequence: FLQFKTWWI
Position: 363-371
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: P1
Chemical type: Peptide from protein
Sequence: FLQFKTWWI
Position: 363-371
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P1
Chemical type: Peptide from protein
Sequence: FLQFKTWWI
Position: 363-371
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P1
Chemical type: Peptide from protein
Sequence: FLQFKTWWI
Position: 363-371
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: P1
Chemical type: Peptide from protein
Sequence: FLQFKTWWI
Position: 363-371
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: P1
Chemical type: Peptide from protein
Sequence: FLQFKTWWI
Position: 363-371
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P1
Chemical type: Peptide from protein
Sequence: FLQFKTWWI
Position: 363-371
Source molecule (GenBank): P63126
Assay category: MhcLigandElution
Result: Positive

Epitope: P1
Chemical type: Peptide from protein
Sequence: FLQFKTWWI
Position: 363-371
Source molecule (GenBank): P63126
Assay category: MhcLigandElution
Result: Positive

Epitope: P1
Chemical type: Peptide from protein
Sequence: FLQFKTWWI
Position: 363-371
Source molecule (GenBank): P63126
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 733.2

Epitope: P2
Chemical type: Peptide from protein
Sequence: RLIPYDWEI
Position: 344-352
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: P2
Chemical type: Peptide from protein
Sequence: RLIPYDWEI
Position: 344-352
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P2
Chemical type: Peptide from protein
Sequence: RLIPYDWEI
Position: 344-352
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P2
Chemical type: Peptide from protein
Sequence: RLIPYDWEI
Position: 344-352
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: P2
Chemical type: Peptide from protein
Sequence: RLIPYDWEI
Position: 344-352
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive-Low
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: P2
Chemical type: Peptide from protein
Sequence: RLIPYDWEI
Position: 344-352
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P2
Chemical type: Peptide from protein
Sequence: RLIPYDWEI
Position: 344-352
Source molecule (GenBank): P63126
Assay category: MhcLigandElution
Result: Positive

Epitope: P2
Chemical type: Peptide from protein
Sequence: RLIPYDWEI
Position: 344-352
Source molecule (GenBank): P63126
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1229.4

Epitope: P3
Chemical type: Peptide from protein
Sequence: KLIDCYTFL
Position: 208-216
Source molecule (GenBank): Q9BXR3.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P3
Chemical type: Peptide from protein
Sequence: KLIDCYTFL
Position: 208-216
Source molecule (GenBank): Q9BXR3.2
Assay category: TCell
Result: Negative
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: P3
Chemical type: Peptide from protein
Sequence: KLIDCYTFL
Position: 208-216
Source molecule (GenBank): Q9BXR3.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P3
Chemical type: Peptide from protein
Sequence: KLIDCYTFL
Position: 208-216
Source molecule (GenBank): Q9BXR3.2
Assay category: MhcLigandElution
Result: Positive

Epitope: P3
Chemical type: Peptide from protein
Sequence: KLIDCYTFL
Position: 208-216
Source molecule (GenBank): Q9BXR3.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2436.6

Epitope: P4
Chemical type: Peptide from protein
Sequence: YLSFIKILL
Position: 15-23
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P4
Chemical type: Peptide from protein
Sequence: YLSFIKILL
Position: 15-23
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P4
Chemical type: Peptide from protein
Sequence: YLSFIKILL
Position: 15-23
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: P4
Chemical type: Peptide from protein
Sequence: YLSFIKILL
Position: 15-23
Source molecule (GenBank): P63126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P4
Chemical type: Peptide from protein
Sequence: YLSFIKILL
Position: 15-23
Source molecule (GenBank): P63126
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1245.6

Epitope: P5
Chemical type: Peptide from protein
Sequence: AMIPKDWPL
Position: 110-118
Source molecule (GenBank): Q9BXR3.2
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P5
Chemical type: Peptide from protein
Sequence: AMIPKDWPL
Position: 110-118
Source molecule (GenBank): Q9BXR3.2
Assay category: TCell
Result: Positive
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: P5
Chemical type: Peptide from protein
Sequence: AMIPKDWPL
Position: 110-118
Source molecule (GenBank): Q9BXR3.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P5
Chemical type: Peptide from protein
Sequence: AMIPKDWPL
Position: 110-118
Source molecule (GenBank): Q9BXR3.2
Assay category: MhcLigandElution
Result: Positive

Epitope: P5
Chemical type: Peptide from protein
Sequence: AMIPKDWPL
Position: 110-118
Source molecule (GenBank): Q9BXR3.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2104.9

Epitope: P6
Chemical type: Peptide from protein
Sequence: YAMSNLFSI
Position: 287-295
Source molecule (GenBank): Q9BXR3.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P6
Chemical type: Peptide from protein
Sequence: YAMSNLFSI
Position: 287-295
Source molecule (GenBank): Q9BXR3.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P6
Chemical type: Peptide from protein
Sequence: YAMSNLFSI
Position: 287-295
Source molecule (GenBank): Q9BXR3.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P6
Chemical type: Peptide from protein
Sequence: YAMSNLFSI
Position: 287-295
Source molecule (GenBank): Q9BXR3.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P6
Chemical type: Peptide from protein
Sequence: YAMSNLFSI
Position: 287-295
Source molecule (GenBank): Q9BXR3.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: P6
Chemical type: Peptide from protein
Sequence: YAMSNLFSI
Position: 287-295
Source molecule (GenBank): Q9BXR3.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: P6
Chemical type: Peptide from protein
Sequence: YAMSNLFSI
Position: 287-295
Source molecule (GenBank): Q9BXR3.2
Assay category: TCell
Result: Positive
Cell type: tumor infiltrating lymphocyte
Tissue: breast
Culture conditions: Direct Ex Vivo

Epitope: P6
Chemical type: Peptide from protein
Sequence: YAMSNLFSI
Position: 287-295
Source molecule (GenBank): Q9BXR3.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P6
Chemical type: Peptide from protein
Sequence: YAMSNLFSI
Position: 287-295
Source molecule (GenBank): Q9BXR3.2
Assay category: MhcLigandElution
Result: Positive

Epitope: P6
Chemical type: Peptide from protein
Sequence: YAMSNLFSI
Position: 287-295
Source molecule (GenBank): Q9BXR3.2
Assay category: MhcLigandElution
Result: Positive

Epitope: P6
Chemical type: Peptide from protein
Sequence: YAMSNLFSI
Position: 287-295
Source molecule (GenBank): Q9BXR3.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2817.0