Reference: Taku Fukuzawa; Zenjiro Sampei; Kenta Haraya; Yoshinao Ruike; Meiri Shida-Kawazoe; Yuichiro Shimizu; Siok Wan Gan; Machiko Irie; Yoshinori Tsuboi; Hitoshi Tai; Tetsushi Sakiyama; Akihisa Sakamoto; Shinya Ishii; Atsuhiko Maeda; Yuki Iwayanagi; Norihito Shibahara; Mitsuko Shibuya; Genki Nakamura; Takeru Nambu; Akira Hayasaka; Futa Mimoto; Yuu Okura; Yuji Hori; Kiyoshi Habu; Manabu Wada; Takaaki Miura; Tatsuhiko Tachibana; Kiyofumi Honda; Hiroyuki Tsunoda; Takehisa Kitazawa; Yoshiki Kawabe; Tomoyuki Igawa; Kunihiro Hattori; Junichi Nezu. "Long lasting neutralization of C5 by SKY59, a novel recycling antibody, is a potential therapy for complement-mediated diseases." Scientific reports (2017).

Epitope: Epitope of SKY59 on complement C5 MG1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T47, E48, A49, F50, D51, A52, T53, K57, H70, V71, H72, S74, E76, V107, S108, K109, H110
Source molecule (GenBank): P01031.4
Assay category: BCell
Result: Positive
Host:  12-16 weeks

Epitope: Epitope of SKY59 on complement C5 MG1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T47, E48, A49, F50, D51, A52, T53, K57, H70, V71, H72, S74, E76, V107, S108, K109, H110
Source molecule (GenBank): P01031.4
Assay category: BCell
Result: Positive
Quantitative measurement: 0.197
Host:  12-16 weeks

Epitope: Epitope of SKY59 on complement C5 MG1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T47, E48, A49, F50, D51, A52, T53, K57, H70, V71, H72, S74, E76, V107, S108, K109, H110
Source molecule (GenBank): P01031.4
Assay category: BCell
Result: Positive
Quantitative measurement: 1720000.0
Host:  12-16 weeks

Epitope: Epitope of SKY59 on complement C5 MG1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T47, E48, A49, F50, D51, A52, T53, K57, H70, V71, H72, S74, E76, V107, S108, K109, H110
Source molecule (GenBank): P01031.4
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000338
Host:  12-16 weeks

Epitope: Epitope of SKY59 on complement C5 MG1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T47, E48, A49, F50, D51, A52, T53, K57, H70, V71, H72, S74, E76, V107, S108, K109, H110
Source molecule (GenBank): P01031.4
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000218
Host:  12-16 weeks

Epitope: Epitope of SKY59 on complement C5 MG1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T47, E48, A49, F50, D51, A52, T53, K57, H70, V71, H72, S74, E76, V107, S108, K109, H110
Source molecule (GenBank): P01031.4
Assay category: BCell
Result: Positive
Quantitative measurement: 2.11
Host:  12-16 weeks

Epitope: Epitope of SKY59 on complement C5 MG1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T47, E48, A49, F50, D51, A52, T53, K57, H70, V71, H72, S74, E76, V107, S108, K109, H110
Source molecule (GenBank): P01031.4
Assay category: BCell
Result: Positive
Quantitative measurement: 0.152
Host:  12-16 weeks

Epitope: Epitope of SKY59 on complement C5 MG1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T47, E48, A49, F50, D51, A52, T53, K57, H70, V71, H72, S74, E76, V107, S108, K109, H110
Source molecule (GenBank): P01031.4
Assay category: BCell
Result: Positive
Quantitative measurement: 1440000.0
Host:  12-16 weeks

Epitope: Epitope of SKY59 on complement C5 MG1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T47, E48, A49, F50, D51, A52, T53, K57, H70, V71, H72, S74, E76, V107, S108, K109, H110
Source molecule (GenBank): P01031.4
Assay category: BCell
Result: Positive
Host:  12-16 weeks