Reference: Zhen-yong Keck; Christine Girard-Blanc; Wenyan Wang; Patrick Lau; Adam Zuiani; Felix A Rey; Thomas Krey; Michael S Diamond; Steven K H Foung. "Antibody Response to Hypervariable Region 1 Interferes with Broadly Neutralizing Antibodies to Hepatitis C Virus." Journal of virology (2016).

Epitope: Epitope of HC33.4 Fab on HCV E2
Chemical type: Peptide from protein
Sequence: NGSWH
Position: 417-421
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC33.4 Fab on HCV E2
Chemical type: Peptide from protein
Sequence: NGSWH
Position: 417-421
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC33.4 Fab on HCV E2
Chemical type: Peptide from protein
Sequence: NGSWH
Position: 417-421
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive
Quantitative measurement: 1.65

Epitope: Epitope of HC33.8 Fab on HCV E2
Chemical type: Peptide from protein
Sequence: NTNGSWHIN
Position: 415-423
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC33.8 Fab on HCV E2
Chemical type: Peptide from protein
Sequence: NTNGSWHIN
Position: 415-423
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive
Quantitative measurement: 1.9

Epitope: Epitope of H77.39 mAb on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: I414, N415, N417, G418, W420
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC33.1 mAb on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L413, I414, G418, W420
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC33.1 mAb on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: L413, I414, G418, W420
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC33.29 mAb on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: K408, L413, G418, W420
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC-1 mAb on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: W529, G530, D535
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC84.20 mAb on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T425, A426, N428, C429, W437, G440, L441, F442, Y443, G530, D535, Y613, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC84.24 mAb on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: C429, F442, Y443, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC84.26 mAb on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: C429, L441, F442, Y443, K446, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC84.26 mAb on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: C429, L441, F442, Y443, K446, W616
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC-11 mAb on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T425, N428, G436, W437, L438, F442, Y443, G530, D535
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive

Epitope: Epitope of HC-11 mAb on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: T425, N428, G436, W437, L438, F442, Y443, G530, D535
Source molecule (GenBank): P27958.3
Assay category: BCell
Result: Positive