Reference: Kurt A Jenkins; Miso Park; Magali Pederzoli-Ribeil; Ugur Eskiocak; Parker Johnson; Wilson Guzman; Megan McLaughlin; Deborah Moore-Lai; Caitlin O'Toole; Zhen Liu; Benjamin Nicholson; Veronica Flesch; Huawei Qiu; Tim Clackson; Ronan C O'Hagan; Ulrich Rodeck; Margaret Karow; Jennifer O'Neil; John C Williams. "XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 monoclonal antibody, demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer." Journal for immunotherapy of cancer (2023).

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPGKGLPSC)
Chemical type: Peptide, no natural source
Sequence: CPGKGLPSC
Assay category: BCell
Result: Positive

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPGKGLPSC)
Chemical type: Peptide, no natural source
Sequence: CPGKGLPSC
Assay category: BCell
Result: Positive

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPGKGLPSC)
Chemical type: Peptide, no natural source
Sequence: CPGKGLPSC
Assay category: BCell
Result: Positive

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPGKGLPSC)
Chemical type: Peptide, no natural source
Sequence: CPGKGLPSC
Assay category: BCell
Result: Positive

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPGKGLPSC)
Chemical type: Peptide, no natural source
Sequence: CPGKGLPSC
Assay category: BCell
Result: Positive
Quantitative measurement: 1620000.0

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPGKGLPSC)
Chemical type: Peptide, no natural source
Sequence: CPGKGLPSC
Assay category: BCell
Result: Positive
Quantitative measurement: 1.68

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPGKGLPSC)
Chemical type: Peptide, no natural source
Sequence: CPGKGLPSC
Assay category: BCell
Result: Positive
Quantitative measurement: 0.16

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPGKGLPSC)
Chemical type: Peptide, no natural source
Sequence: CPGKGLPSC
Assay category: BCell
Result: Positive
Quantitative measurement: 0.091

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPGKGLPSC)
Chemical type: Peptide, no natural source
Sequence: CPGKGLPSC
Assay category: BCell
Result: Positive
Quantitative measurement: 366000.0

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPGKGLPSC)
Chemical type: Peptide, no natural source
Sequence: CPGKGLPSC
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000333

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPGKGLPSC)
Chemical type: Peptide, no natural source
Sequence: CPGKGLPSC
Assay category: BCell
Result: Positive

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPGKGLPSC)
Chemical type: Peptide, no natural source
Sequence: CPGKGLPSC
Assay category: BCell
Result: Positive
Quantitative measurement: 3.0

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPGKGLPSC)
Chemical type: Peptide, no natural source
Sequence: CPGKGLPSC
Assay category: BCell
Result: Positive
Quantitative measurement: 1040.0

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPFPALELC)
Chemical type: Peptide, no natural source
Sequence: CPFPALELC
Assay category: BCell
Result: Positive

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPFPALELC)
Chemical type: Peptide, no natural source
Sequence: CPFPALELC
Assay category: BCell
Result: Positive
Quantitative measurement: 1080.0

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPFPALELC)
Chemical type: Peptide, no natural source
Sequence: CPFPALELC
Assay category: BCell
Result: Positive
Quantitative measurement: 698000.0

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPFPALELC)
Chemical type: Peptide, no natural source
Sequence: CPFPALELC
Assay category: BCell
Result: Positive
Quantitative measurement: 366000.0

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPFPALELC)
Chemical type: Peptide, no natural source
Sequence: CPFPALELC
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000333

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPFPALELC)
Chemical type: Peptide, no natural source
Sequence: CPFPALELC
Assay category: BCell
Result: Positive

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPFPALELC)
Chemical type: Peptide, no natural source
Sequence: CPFPALELC
Assay category: BCell
Result: Positive

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPFPALELC)
Chemical type: Peptide, no natural source
Sequence: CPFPALELC
Assay category: BCell
Result: Positive

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPFPALELC)
Chemical type: Peptide, no natural source
Sequence: CPFPALELC
Assay category: BCell
Result: Positive
Quantitative measurement: 1.8

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPFPALELC)
Chemical type: Peptide, no natural source
Sequence: CPFPALELC
Assay category: BCell
Result: Positive
Quantitative measurement: 0.75

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPFPALELC)
Chemical type: Peptide, no natural source
Sequence: CPFPALELC
Assay category: BCell
Result: Positive

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPFPALELC)
Chemical type: Peptide, no natural source
Sequence: CPFPALELC
Assay category: BCell
Result: Positive
Quantitative measurement: 0.16

Epitope: XTX100 Fab with CTLA-4 peptide mimic (CPFPALELC)
Chemical type: Peptide, no natural source
Sequence: CPFPALELC
Assay category: BCell
Result: Positive
Quantitative measurement: 0.091