Reference: Scott B Biering; David L Akey; Marcus P Wong; W Clay Brown; Nicholas T N Lo; Henry Puerta-Guardo; Francielle Tramontini Gomes de Sousa; Chunling Wang; Jamie R Konwerski; Diego A Espinosa; Nicholas J Bockhaus; Dustin R Glasner; Jeffrey Li; Sophie F Blanc; Evan Y Juan; Stephen J Elledge; Michael J Mina; P Robert Beatty; Janet L Smith; Eva Harris. "Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction." Science (New York, N.Y.) (2021).

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive
Quantitative measurement: 4.8

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive
Quantitative measurement: 3.2

Epitope: Epitope of 2B7 Fab on DENV1 NS1
Chemical type: Discontinuous protein residues
Discontinuous residues: H1044, L1045, E1056, R1074, T1076, T1077, V1078, T1079, G1080, I1083, E1101, D1102, G1103, W1105, N1119, L1120, V1121, K1122
Source molecule (GenBank): P17763
Assay category: BCell
Result: Positive