Reference: Hien Thy Dao; Tiing Jen Loh; Ravi K Sharma; Lars Klareskog; Vivianne Malmström; Hugh H Reid; Jamie Rossjohn; Jia Jia Lim. "The molecular basis of T cell receptor recognition of citrullinated tenascin-C presented by HLA-DR4." The Journal of biological chemistry (2025).

Epitope: TNC (1014, 1016 cit)
Chemical type: Peptide from protein
Sequence: DRYRLNYSLPTG
Position: 1013-1024
Source molecule (GenBank): P24821.3
Assay category: TCell
Result: Positive
Quantitative measurement: 25800.0

Epitope: TNC (1014, 1016 cit)
Chemical type: Peptide from protein
Sequence: DRYRLNYSLPTG
Position: 1013-1024
Source molecule (GenBank): P24821.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: TNC (1014, 1016 cit)
Chemical type: Peptide from protein
Sequence: DRYRLNYSLPTG
Position: 1013-1024
Source molecule (GenBank): P24821.3
Assay category: TCell
Result: Positive
Quantitative measurement: 50000.0

Epitope: TNC (1014, 1016 cit)
Chemical type: Peptide from protein
Sequence: DRYRLNYSLPTG
Position: 1013-1024
Source molecule (GenBank): P24821.3
Assay category: TCell
Result: Positive
Quantitative measurement: 75500.0

Epitope: TNC (1014, 1016 cit)
Chemical type: Peptide from protein
Sequence: DRYRLNYSLPTG
Position: 1013-1024
Source molecule (GenBank): P24821.3
Assay category: TCell
Result: Positive
Quantitative measurement: 3.2

Epitope: TNC (1014, 1016 cit)
Chemical type: Peptide from protein
Sequence: DRYRLNYSLPTG
Position: 1013-1024
Source molecule (GenBank): P24821.3
Assay category: TCell
Result: Positive
Cell type: HEK293 cell (epithelial cell)
Tissue: kidney
Culture conditions: Engineered

Epitope: TNC (1014, 1016 cit)
Chemical type: Peptide from protein
Sequence: DRYRLNYSLPTG
Position: 1013-1024
Source molecule (GenBank): P24821.3
Assay category: TCell
Result: Positive
Cell type: HEK293 cell (epithelial cell)
Tissue: kidney
Culture conditions: Engineered

Epitope: TNC (1014, 1016 cit)
Chemical type: Peptide from protein
Sequence: DRYRLNYSLPTG
Position: 1013-1024
Source molecule (GenBank): P24821.3
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1140.0

Epitope: TNC (1014, 1016 cit)
Chemical type: Peptide from protein
Sequence: DRYRLNYSLPTG
Position: 1013-1024
Source molecule (GenBank): P24821.3
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1310.0

Epitope: TNC (1014, 1016 cit)
Chemical type: Peptide from protein
Sequence: DRYRLNYSLPTG
Position: 1013-1024
Source molecule (GenBank): P24821.3
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 800.0

Epitope: TNC (1014, 1016 cit)
Chemical type: Peptide from protein
Sequence: DRYRLNYSLPTG
Position: 1013-1024
Source molecule (GenBank): P24821.3
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 300000.0

Epitope: TNC (1014, 1016 cit)
Chemical type: Peptide from protein
Sequence: DRYRLNYSLPTG
Position: 1013-1024
Source molecule (GenBank): P24821.3
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 4810.0

Epitope: TNC (1014, 1016 cit)
Chemical type: Peptide from protein
Sequence: DRYRLNYSLPTG
Position: 1013-1024
Source molecule (GenBank): P24821.3
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 3.2

Epitope: TNC (1014, 1016 cit)
Chemical type: Peptide from protein
Sequence: DRYRLNYSLPTG
Position: 1013-1024
Source molecule (GenBank): P24821.3
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.4

Epitope: TNC (1016 cit)
Chemical type: Peptide from protein
Sequence: DRYRLNYSLPTG
Position: 1013-1024
Source molecule (GenBank): P24821.3
Assay category: TCell
Result: Positive
Quantitative measurement: 50000.0