Reference: Tao Dao; Sung Soo Mun; Zaki Molvi; Tatyana Korontsvit; Martin G Klatt; Abdul G Khan; Elisabeth K Nyakatura; Mary Ann Pohl; Thomas E White; Paul J Balderes; Ivo C Lorenz; Richard J O'Reilly; David A Scheinberg. "A TCR mimic monoclonal antibody reactive with the "public" phospho-neoantigen pIRS2/HLA-A*02:01 complex." JCI insight (2022).

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00055

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive
Quantitative measurement: 340000.0

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive-Intermediate

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive-Intermediate

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive-Low

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Negative

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Negative

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive
Quantitative measurement: 1.6

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive-Low

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive-High

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: TCell
Result: Positive
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: TCell
Result: Negative
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: MhcLigandElution
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: MhcLigandElution
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: MhcLigandElution
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: MhcLigandElution
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: MhcLigandElution
Result: Positive

Epitope: pIRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: MhcBinding
Result: Positive

Epitope: WT-IRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Negative

Epitope: WT-IRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: BCell
Result: Negative

Epitope: WT-IRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: TCell
Result: Negative
Cell type: T cell CD3+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: WT-IRS2
Chemical type: Peptide from protein
Sequence: RVASPTSGV
Position: 1097-1105
Source molecule (GenBank): Q9Y4H2.2
Assay category: MhcBinding
Result: Positive

Epitope: pIRS2 (1097-1106)
Chemical type: Peptide from protein
Sequence: RVASPTSGVK
Position: 1097-1106
Source molecule (GenBank): Q9Y4H2.2
Assay category: MhcLigandElution
Result: Positive

Epitope: pT4
Chemical type: Peptide, no natural source
Sequence: RVATPTSGV
Assay category: BCell
Result: Positive-High

Epitope: pT4
Chemical type: Peptide, no natural source
Sequence: RVATPTSGV
Assay category: MhcBinding
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive
Quantitative measurement: 340000.0

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00055

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive-Low

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive-High

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive
Quantitative measurement: 1.6

Epitope: pRTF
Chemical type: Peptide from protein
Sequence: RTFSPTYGL
Position: 426-434
Source molecule (GenBank): O15061.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00055

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive
Quantitative measurement: 340000.0

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive-High

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive
Quantitative measurement: 1.6

Epitope: MEL-1
Chemical type: Peptide from protein
Sequence: RLQSTSERL
Position: 217-225
Source molecule (GenBank): Q96TA2.2
Assay category: BCell
Result: Positive-Intermediate

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive-High

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive
Quantitative measurement: 1.6

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00055

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive
Quantitative measurement: 340000.0

Epitope: AMD-2
Chemical type: Peptide from protein
Sequence: RQISQDVKL
Position: 165-173
Source molecule (GenBank): Q01433.2
Assay category: BCell
Result: Positive-Low