Reference: Francesco Torre; Matthew Cramp; Ania Owsianka; Ed Dornan; Howard Marsden; William Carman; Roger Williams; Nikolai V Naoumov. "Direct evidence that naturally occurring mutations within hepatitis B core epitope alter CD4+ T-cell reactivity." Journal of medical virology (2004).

Epitope: P0
Chemical type: Peptide from protein
Sequence: PHHTALRQAILCWGELMTLA
Position: 50-69
Source molecule (GenBank): P03149.1
Assay category: TCell
Result: Positive
Host:  16-50 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P0
Chemical type: Peptide from protein
Sequence: PHHTALRQAILCWGELMTLA
Position: 50-69
Source molecule (GenBank): P03149.1
Assay category: TCell
Result: Positive
MHC allele types: 420 437 360 368
Host: M 23-69 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P1a
Chemical type: Peptide from protein
Sequence: PHHTALRQAVLCWGELMTLA
Position: 79-98
Source molecule (GenBank): BAE97616.1
Assay category: TCell
Result: Positive
MHC allele types: 420 437 360 368
Host: M 23-69 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P1a
Chemical type: Peptide from protein
Sequence: PHHTALRQAVLCWGELMTLA
Position: 79-98
Source molecule (GenBank): BAE97616.1
Assay category: TCell
Result: Positive
Host:  16-50 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P1c
Chemical type: Peptide from protein
Sequence: PHHTALRQAILCWGELMNLA
Position: 79-98
Source molecule (GenBank): ABN64040.1
Assay category: TCell
Result: Positive
Host:  16-50 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P1c
Chemical type: Peptide from protein
Sequence: PHHTALRQAILCWGELMNLA
Position: 79-98
Source molecule (GenBank): ABN64040.1
Assay category: TCell
Result: Negative
Host: M 23-69 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P2a
Chemical type: Peptide from protein
Sequence: HHHTALRQAILCWGELMNLA
Position: 50-69
Source molecule (GenBank): AAV70957.1
Assay category: TCell
Result: Positive
Host:  16-50 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P2a
Chemical type: Peptide from protein
Sequence: HHHTALRQAILCWGELMNLA
Position: 50-69
Source molecule (GenBank): AAV70957.1
Assay category: TCell
Result: Positive
Host: M 23-69 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P2c
Chemical type: Peptide from protein
Sequence: PHHTALRQAILCWGDLMNLA
Position: 79-98
Source molecule (GenBank): CAJ33968.1
Assay category: TCell
Result: Positive
MHC allele types: 420 437 360 368 417 364 432 435 358
Host: M 23-69 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P2c
Chemical type: Peptide from protein
Sequence: PHHTALRQAILCWGDLMNLA
Position: 79-98
Source molecule (GenBank): CAJ33968.1
Assay category: TCell
Result: Positive
Host:  16-50 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P3
Chemical type: Peptide from protein
Sequence: PHHTALRQAILCWGDLMNLG
Position: 79-98
Source molecule (GenBank): BAD98548.1
Assay category: TCell
Result: Positive
Host:  16-50 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P3
Chemical type: Peptide from protein
Sequence: PHHTALRQAILCWGDLMNLG
Position: 79-98
Source molecule (GenBank): BAD98548.1
Assay category: TCell
Result: Positive
MHC allele types: 420 437 360 368
Host: M 23-69 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P1b
Chemical type: Peptide from protein
Sequence: PHHTALRQAIVCWGELMTLA
Position: 62-81
Source molecule (GenBank): AAR96254.1
Assay category: TCell
Result: Positive
MHC allele types: 420 437 360 368 52 57
Host: M 23-69 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo