Reference: Lujia Zhou; Lucia Chávez-Gutiérrez; Katrijn Bockstael; Ragna Sannerud; Wim Annaert; Patrick C May; Eric Karran; Bart De Strooper. "Inhibition of beta-secretase in vivo via antibody binding to unique loops (D and F) of BACE1." The Journal of biological chemistry (2011).

Epitope: mAb 1A11 epitope on BACE1
Chemical type: Discontinuous protein residues
Discontinuous residues: Q332, A333, G334, T335, T336, P337, W338, N339, I340, F341, P342, E371, D372, V373, A374, T375, S376, Q377, D378
Source molecule (GenBank): P56817.2
Assay category: BCell
Result: Positive
Host:  9 weeks

Epitope: mAb 1A11 epitope on BACE1
Chemical type: Discontinuous protein residues
Discontinuous residues: Q332, A333, G334, T335, T336, P337, W338, N339, I340, F341, P342, E371, D372, V373, A374, T375, S376, Q377, D378
Source molecule (GenBank): P56817.2
Assay category: BCell
Result: Positive
Host:  9 weeks

Epitope: mAb 1A11 epitope on BACE1
Chemical type: Discontinuous protein residues
Discontinuous residues: Q332, A333, G334, T335, T336, P337, W338, N339, I340, F341, P342, E371, D372, V373, A374, T375, S376, Q377, D378
Source molecule (GenBank): P56817.2
Assay category: BCell
Result: Positive
Host:  9 weeks

Epitope: mAb 1A11 epitope on BACE1
Chemical type: Discontinuous protein residues
Discontinuous residues: Q332, A333, G334, T335, T336, P337, W338, N339, I340, F341, P342, E371, D372, V373, A374, T375, S376, Q377, D378
Source molecule (GenBank): P56817.2
Assay category: BCell
Result: Positive
Host:  9 weeks

Epitope: mAb 1A11 epitope on BACE1
Chemical type: Discontinuous protein residues
Discontinuous residues: Q332, A333, G334, T335, T336, P337, W338, N339, I340, F341, P342, E371, D372, V373, A374, T375, S376, Q377, D378
Source molecule (GenBank): P56817.2
Assay category: BCell
Result: Positive
Host:  9 weeks

Epitope: mAb 1A11 epitope on BACE1
Chemical type: Discontinuous protein residues
Discontinuous residues: Q332, A333, G334, T335, T336, P337, W338, N339, I340, F341, P342, E371, D372, V373, A374, T375, S376, Q377, D378
Source molecule (GenBank): P56817.2
Assay category: BCell
Result: Positive
Host:  9 weeks

Epitope: mAb 1A11 epitope on BACE1
Chemical type: Discontinuous protein residues
Discontinuous residues: Q332, A333, G334, T335, T336, P337, W338, N339, I340, F341, P342, E371, D372, V373, A374, T375, S376, Q377, D378
Source molecule (GenBank): P56817.2
Assay category: BCell
Result: Positive
Host:  9 weeks

Epitope: mAb 5G7 on BACE1
Chemical type: Peptide from protein
Sequence: RLPKKVFEAAVKSIKAASS
Position: 296-314
Source molecule (GenBank): P56817.2
Assay category: BCell
Result: Positive
Host:  9 weeks

Epitope: mAb 5G7 on BACE1
Chemical type: Peptide from protein
Sequence: RLPKKVFEAAVKSIKAASS
Position: 296-314
Source molecule (GenBank): P56817.2
Assay category: BCell
Result: Positive
Host:  9 weeks

Epitope: mAb 5G7 on BACE1
Chemical type: Peptide from protein
Sequence: RLPKKVFEAAVKSIKAASS
Position: 296-314
Source molecule (GenBank): P56817.2
Assay category: BCell
Result: Positive
Host:  9 weeks

Epitope: mAb 5G7 on BACE1
Chemical type: Peptide from protein
Sequence: RLPKKVFEAAVKSIKAASS
Position: 296-314
Source molecule (GenBank): P56817.2
Assay category: BCell
Result: Positive
Host:  9 weeks

Epitope: mAb 5G7 on BACE1
Chemical type: Peptide from protein
Sequence: RLPKKVFEAAVKSIKAASS
Position: 296-314
Source molecule (GenBank): P56817.2
Assay category: BCell
Result: Positive
Host:  9 weeks

Epitope: mAb 5G7 on BACE1
Chemical type: Peptide from protein
Sequence: RLPKKVFEAAVKSIKAASS
Position: 296-314
Source molecule (GenBank): P56817.2
Assay category: BCell
Result: Positive
Host:  9 weeks