Reference: Jie Ning; Yue Xu; Yayi Ren; Zelin Zhang; Ying Chen; Xianhuang Zeng; Jianquan Zhang; Chao Wu. "Immunodominant T cell responses to SARS-CoV-2 nucleocapsid protein in Omicron breakthrough infection post-inactivated vaccination." Virulence (2025).

Epitope: JN.1 N-24
Chemical type: Peptide from protein
Sequence: LNTPKDHIGTRNPANNAA
Position: 136-153
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-24
Chemical type: Peptide from protein
Sequence: LNTPKDHIGTRNPANNAA
Position: 136-153
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-24
Chemical type: Peptide from protein
Sequence: LNTPKDHIGTRNPANNAA
Position: 136-153
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-24
Chemical type: Peptide from protein
Sequence: LNTPKDHIGTRNPANNAA
Position: 136-153
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-24
Chemical type: Peptide from protein
Sequence: LNTPKDHIGTRNPANNAA
Position: 136-153
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-24
Chemical type: Peptide from protein
Sequence: LNTPKDHIGTRNPANNAA
Position: 136-153
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-24
Chemical type: Peptide from protein
Sequence: LNTPKDHIGTRNPANNAA
Position: 139-156
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-24
Chemical type: Peptide from protein
Sequence: LNTPKDHIGTRNPANNAA
Position: 139-156
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-24
Chemical type: Peptide from protein
Sequence: LNTPKDHIGTRNPANNAA
Position: 139-156
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-24
Chemical type: Peptide from protein
Sequence: LNTPKDHIGTRNPANNAA
Position: 139-156
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-24
Chemical type: Peptide from protein
Sequence: LNTPKDHIGTRNPANNAA
Position: 139-156
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-24
Chemical type: Peptide from protein
Sequence: LNTPKDHIGTRNPANNAA
Position: 139-156
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-4
Chemical type: Peptide from protein
Sequence: GPSDSTGSNQNGERSGAR
Position: 19-36
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-4
Chemical type: Peptide from protein
Sequence: GPSDSTGSNQNGERSGAR
Position: 19-36
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-14
Chemical type: Peptide from protein
Sequence: SPDDQIGYYRRATRRIRG
Position: 79-96
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-14
Chemical type: Peptide from protein
Sequence: SPDDQIGYYRRATRRIRG
Position: 79-96
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-33
Chemical type: Peptide from protein
Sequence: SSRNSTPGSSRGTSPARM
Position: 193-210
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-33
Chemical type: Peptide from protein
Sequence: SSRNSTPGSSRGTSPARM
Position: 193-210
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-37
Chemical type: Peptide from protein
Sequence: AALALLLLDRLNQLESKM
Position: 217-234
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-37
Chemical type: Peptide from protein
Sequence: AALALLLLDRLNQLESKM
Position: 217-234
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-44
Chemical type: Peptide from protein
Sequence: RQKRTATKAYNVTQAFGR
Position: 259-276
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-44
Chemical type: Peptide from protein
Sequence: RQKRTATKAYNVTQAFGR
Position: 259-276
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-46
Chemical type: Peptide from protein
Sequence: TQAFGRRGPEQTQGNFGD
Position: 271-288
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-46
Chemical type: Peptide from protein
Sequence: TQAFGRRGPEQTQGNFGD
Position: 271-288
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-51
Chemical type: Peptide from protein
Sequence: WPQIAQFAPSASAFFGMS
Position: 301-318
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-51
Chemical type: Peptide from protein
Sequence: WPQIAQFAPSASAFFGMS
Position: 301-318
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-52
Chemical type: Peptide from protein
Sequence: FAPSASAFFGMSRIGMEV
Position: 307-324
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-52
Chemical type: Peptide from protein
Sequence: FAPSASAFFGMSRIGMEV
Position: 307-324
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-53
Chemical type: Peptide from protein
Sequence: AFFGMSRIGMEVTPSGTW
Position: 313-330
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-53
Chemical type: Peptide from protein
Sequence: AFFGMSRIGMEVTPSGTW
Position: 313-330
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-61
Chemical type: Peptide from protein
Sequence: KTFPPTEPKKDKKKKADE
Position: 361-378
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-61
Chemical type: Peptide from protein
Sequence: KTFPPTEPKKDKKKKADE
Position: 361-378
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-64
Chemical type: Peptide from protein
Sequence: TQALPQRQKKQQTVTLLP
Position: 379-396
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-64
Chemical type: Peptide from protein
Sequence: TQALPQRQKKQQTVTLLP
Position: 379-396
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-65
Chemical type: Peptide from protein
Sequence: RQKKQQTVTLLPAADLDD
Position: 385-402
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-65
Chemical type: Peptide from protein
Sequence: RQKKQQTVTLLPAADLDD
Position: 385-402
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-66
Chemical type: Peptide from protein
Sequence: TVTLLPAADLDDFSKQLQ
Position: 391-408
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-66
Chemical type: Peptide from protein
Sequence: TVTLLPAADLDDFSKQLQ
Position: 391-408
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-14
Chemical type: Peptide from protein
Sequence: SPDDQIGYYRRATRRIRG
Position: 76-93
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-14
Chemical type: Peptide from protein
Sequence: SPDDQIGYYRRATRRIRG
Position: 76-93
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-44
Chemical type: Peptide from protein
Sequence: RQKRTATKAYNVTQAFGR
Position: 256-273
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-44
Chemical type: Peptide from protein
Sequence: RQKRTATKAYNVTQAFGR
Position: 256-273
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-46
Chemical type: Peptide from protein
Sequence: TQAFGRRGPEQTQGNFGD
Position: 268-285
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-46
Chemical type: Peptide from protein
Sequence: TQAFGRRGPEQTQGNFGD
Position: 268-285
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-51
Chemical type: Peptide from protein
Sequence: WPQIAQFAPSASAFFGMS
Position: 298-315
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-51
Chemical type: Peptide from protein
Sequence: WPQIAQFAPSASAFFGMS
Position: 298-315
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-52
Chemical type: Peptide from protein
Sequence: FAPSASAFFGMSRIGMEV
Position: 304-321
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-52
Chemical type: Peptide from protein
Sequence: FAPSASAFFGMSRIGMEV
Position: 304-321
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-53
Chemical type: Peptide from protein
Sequence: AFFGMSRIGMEVTPSGTW
Position: 310-327
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-53
Chemical type: Peptide from protein
Sequence: AFFGMSRIGMEVTPSGTW
Position: 310-327
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-61
Chemical type: Peptide from protein
Sequence: KTFPPTEPKKDKKKKADE
Position: 358-375
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-61
Chemical type: Peptide from protein
Sequence: KTFPPTEPKKDKKKKADE
Position: 358-375
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-64
Chemical type: Peptide from protein
Sequence: TQALPQRQKKQQTVTLLP
Position: 376-393
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-64
Chemical type: Peptide from protein
Sequence: TQALPQRQKKQQTVTLLP
Position: 376-393
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-65
Chemical type: Peptide from protein
Sequence: RQKKQQTVTLLPAADLDD
Position: 382-399
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-65
Chemical type: Peptide from protein
Sequence: RQKKQQTVTLLPAADLDD
Position: 382-399
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-66
Chemical type: Peptide from protein
Sequence: TVTLLPAADLDDFSKQLQ
Position: 388-405
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-66
Chemical type: Peptide from protein
Sequence: TVTLLPAADLDDFSKQLQ
Position: 388-405
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-24 14mer-1
Chemical type: Peptide from protein
Sequence: LNTPKDHIGTRNPA
Position: 136-149
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-24 14mer-3
Chemical type: Peptide from protein
Sequence: TPKDHIGTRNPANN
Position: 138-151
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-24 14mer-4
Chemical type: Peptide from protein
Sequence: PKDHIGTRNPANNA
Position: 139-152
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-24 14mer-4
Chemical type: Peptide from protein
Sequence: PKDHIGTRNPANNA
Position: 139-152
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: JN.1 N-24 14mer-5
Chemical type: Peptide from protein
Sequence: KDHIGTRNPANNAA
Position: 140-153
Source molecule (GenBank): XPD16435.1
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-24 14mer-1
Chemical type: Peptide from protein
Sequence: LNTPKDHIGTRNPA
Position: 139-152
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-24 14mer-3
Chemical type: Peptide from protein
Sequence: TPKDHIGTRNPANN
Position: 141-154
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-24 14mer-4
Chemical type: Peptide from protein
Sequence: PKDHIGTRNPANNA
Position: 142-155
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-24 14mer-4
Chemical type: Peptide from protein
Sequence: PKDHIGTRNPANNA
Position: 142-155
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Positive
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N-24 14mer-5
Chemical type: Peptide from protein
Sequence: KDHIGTRNPANNAA
Position: 143-156
Source molecule (GenBank): YP_009724397.2
Assay category: TCell
Result: Negative
Host:  18-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo