Reference: Cassandra E Smith; Stephen D Miller. "Multi-peptide coupled-cell tolerance ameliorates ongoing relapsing EAE associated with multiple pathogenic autoreactivities." Journal of autoimmunity (2006).

Epitope: MBP<sub>84-104</sub>
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTPPPSQGKGR
Position: 111-131
Source molecule (GenBank): AAB59711.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks

Epitope: MBP<sub>84-104</sub>
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTPPPSQGKGR
Position: 111-131
Source molecule (GenBank): AAB59711.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>84-104</sub>
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTPPPSQGKGR
Position: 111-131
Source molecule (GenBank): AAB59711.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>84-104</sub>
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTPPPSQGKGR
Position: 111-131
Source molecule (GenBank): AAB59711.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>84-104</sub>
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTPPPSQGKGR
Position: 111-131
Source molecule (GenBank): AAB59711.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks

Epitope: MBP<sub>84-104</sub>
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTPPPSQGKGR
Position: 111-131
Source molecule (GenBank): AAB59711.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymphocyte
Tissue: central nervous system (CNS)
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>84-104</sub>
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTPPPSQGKGR
Position: 111-131
Source molecule (GenBank): AAB59711.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>92-106</sub>
Chemical type: Peptide from protein
Sequence: DEGGYTCFFRDHSYQ
Position: 120-134
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks

Epitope: MOG<sub>92-106</sub>
Chemical type: Peptide from protein
Sequence: DEGGYTCFFRDHSYQ
Position: 120-134
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks

Epitope: MOG<sub>92-106</sub>
Chemical type: Peptide from protein
Sequence: DEGGYTCFFRDHSYQ
Position: 120-134
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>92-106</sub>
Chemical type: Peptide from protein
Sequence: DEGGYTCFFRDHSYQ
Position: 120-134
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>92-106</sub>
Chemical type: Peptide from protein
Sequence: DEGGYTCFFRDHSYQ
Position: 120-134
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>92-106</sub>
Chemical type: Peptide from protein
Sequence: DEGGYTCFFRDHSYQ
Position: 120-134
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG<sub>92-106</sub>
Chemical type: Peptide from protein
Sequence: DEGGYTCFFRDHSYQ
Position: 120-134
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymphocyte
Tissue: central nervous system (CNS)
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>178-191</sub>
Chemical type: Peptide from protein
Sequence: NTWTTSQSIAFPSK
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>178-191</sub>
Chemical type: Peptide from protein
Sequence: NTWTTSQSIAFPSK
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymphocyte
Tissue: central nervous system (CNS)
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>178-191</sub>
Chemical type: Peptide from protein
Sequence: NTWTTSQSIAFPSK
Assay category: TCell
Result: Positive
Host: F 8-10 weeks

Epitope: PLP<sub>178-191</sub>
Chemical type: Peptide from protein
Sequence: NTWTTSQSIAFPSK
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>178-191</sub>
Chemical type: Peptide from protein
Sequence: NTWTTSQSIAFPSK
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>178-191</sub>
Chemical type: Peptide from protein
Sequence: NTWTTSQSIAFPSK
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP<sub>178-191</sub>
Chemical type: Peptide from protein
Sequence: NTWTTSQSIAFPSK
Assay category: TCell
Result: Positive
Host: F 8-10 weeks

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymphocyte
Tissue: central nervous system (CNS)
Culture conditions: Direct Ex Vivo

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 8-10 weeks

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 8-10 weeks

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo