Reference: Hayk Davtyan; Anahit Ghochikyan; Irina Petrushina; Armine Hovakimyan; Arpine Davtyan; David H Cribbs; Michael G Agadjanyan. "The MultiTEP platform-based Alzheimer's disease epitope vaccine activates a broad repertoire of T helper cells in nonhuman primates." Alzheimer's & dementia : the journal of the Alzheimer's Association (2014).

Epitope: A beta (2-6)
Chemical type: Peptide from protein
Sequence: AEFRH
Position: 673-677
Source molecule (GenBank): AAB59502.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: A beta (2-6)
Chemical type: Peptide from protein
Sequence: AEFRH
Position: 673-677
Source molecule (GenBank): AAB59502.1
Assay category: BCell
Result: Negative
Host: M 2 years 8 months-3 years 9 months

Epitope: A beta (2-6)
Chemical type: Peptide from protein
Sequence: AEFRH
Position: 673-677
Source molecule (GenBank): AAB59502.1
Assay category: BCell
Result: Positive
Host: M 2 years 8 months-3 years 9 months

Epitope: A beta (2-6)
Chemical type: Peptide from protein
Sequence: AEFRH
Position: 673-677
Source molecule (GenBank): AAB59502.1
Assay category: BCell
Result: Positive
Host: M 2 years 8 months-3 years 9 months

Epitope: A beta (2-6)
Chemical type: Peptide from protein
Sequence: AEFRH
Position: 673-677
Source molecule (GenBank): AAB59502.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: PADRE
Chemical type: Peptide, no natural source
Sequence: AKFVAAWTLKAAA
Assay category: TCell
Result: Positive
Host: M 6-8 weeks
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PADRE
Chemical type: Peptide, no natural source
Sequence: AKFVAAWTLKAAA
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: P23
Chemical type: Peptide from protein
Sequence: VSIDKFRIFCKANPK
Assay category: TCell
Result: Positive
Host: M 6-8 weeks
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P23
Chemical type: Peptide from protein
Sequence: VSIDKFRIFCKANPK
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: P32 (1174-1189)
Chemical type: Peptide from protein
Sequence: LKFIIKRYTPNNEIDS
Position: 1173-1188
Source molecule (GenBank): P04958.2
Assay category: TCell
Result: Positive
Host: M 6-8 weeks
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P32 (1174-1189)
Chemical type: Peptide from protein
Sequence: LKFIIKRYTPNNEIDS
Position: 1173-1188
Source molecule (GenBank): P04958.2
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: P21
Chemical type: Peptide from protein
Sequence: IREDNNITLKLDRCNN
Position: 1064-1079
Source molecule (GenBank): P04958.2
Assay category: TCell
Result: Positive
Host: M 6-8 weeks
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P21
Chemical type: Peptide from protein
Sequence: IREDNNITLKLDRCNN
Position: 1064-1079
Source molecule (GenBank): P04958.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: P30
Chemical type: Peptide from protein
Sequence: FNNFTVSFWLRVPKVSASHLE
Position: 947-967
Source molecule (GenBank): P04958.2
Assay category: TCell
Result: Positive
Host: M 6-8 weeks
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P30
Chemical type: Peptide from protein
Sequence: FNNFTVSFWLRVPKVSASHLE
Position: 947-967
Source molecule (GenBank): P04958.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: P2
Chemical type: Peptide from protein
Sequence: QYIKANSKFIGITE
Position: 830-843
Source molecule (GenBank): P04958.2
Assay category: TCell
Result: Positive
Host: M 6-8 weeks
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P2
Chemical type: Peptide from protein
Sequence: QYIKANSKFIGITE
Position: 830-843
Source molecule (GenBank): P04958.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBVnc
Chemical type: Peptide from protein
Sequence: PHHTALRQAILCWGELMTLA
Position: 50-69
Source molecule (GenBank): CAA92251.1
Assay category: TCell
Result: Positive
Host: M 6-8 weeks
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBVnc
Chemical type: Peptide from protein
Sequence: PHHTALRQAILCWGELMTLA
Position: 50-69
Source molecule (GenBank): CAA92251.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBsAg
Chemical type: Peptide from protein
Sequence: FFLLTRILTIPQSLD
Position: 19-33
Source molecule (GenBank): BAF42669.1
Assay category: TCell
Result: Positive
Host: M 6-8 weeks
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBsAg
Chemical type: Peptide from protein
Sequence: FFLLTRILTIPQSLD
Position: 19-33
Source molecule (GenBank): BAF42669.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MT
Chemical type: Peptide from protein
Sequence: YSGPLKAEIAQRLEDV
Assay category: TCell
Result: Positive
Host: M 6-8 weeks
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MT
Chemical type: Peptide from protein
Sequence: YSGPLKAEIAQRLEDV
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: P17
Chemical type: Peptide from protein
Sequence: LINSTKIYSYFPSVISKVNQ
Position: 586-605
Source molecule (GenBank): P04958.2
Assay category: TCell
Result: Positive
Host: M 6-8 weeks
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P17
Chemical type: Peptide from protein
Sequence: LINSTKIYSYFPSVISKVNQ
Position: 586-605
Source molecule (GenBank): P04958.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: P28
Chemical type: Peptide from protein
Sequence: LEYIPEITLPVIAALSIAES
Position: 674-693
Source molecule (GenBank): P04958.2
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: P28
Chemical type: Peptide from protein
Sequence: LEYIPEITLPVIAALSIAES
Position: 674-693
Source molecule (GenBank): P04958.2
Assay category: TCell
Result: Positive
Host: M 6-8 weeks
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo