Reference: Laura A Powell; Andrew Miller; Julie M Fox; Nurgun Kose; Thomas Klose; Arthur S Kim; Robin Bombardi; Rashika N Tennekoon; A Dharshan de Silva; Robert H Carnahan; Michael S Diamond; Michael G Rossmann; Richard J Kuhn; James E Crowe. "Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site." Cell host & microbe (2020).

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Negative
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on RRV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, T184, A185, N187, I222, D223, Q224
Source molecule (GenBank): AAA47405.1
Assay category: BCell
Result: Positive

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Negative
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive

Epitope: Epitope of RRV-12 Fab on CHIK E2
Chemical type: Discontinuous protein residues
Discontinuous residues: S193, Q194, Q195, S196, G197, N198, N230, C231, K232
Source molecule (GenBank): AHK22774.1
Assay category: BCell
Result: Positive

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Negative
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive
Host: F 50 years

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive

Epitope: Epitope of RRV-12 Fab on MAYV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: Q183, Q184, S185, G186, N187, K189, T221, V222, D223, K224
Source molecule (GenBank): NP_740693.1
Assay category: BCell
Result: Positive
Host: F 50 years