Reference: Isla S Humphreys; Annette von Delft; Anthony Brown; Linda Hibbert; Jane D Collier; Graham R Foster; Monira Rahman; Annabel Christian; Paul Klenerman; Eleanor Barnes. "HCV genotype-3a T cell immunity: specificity, function and impact of therapy." Gut (2012).

Epitope: HCV (27-44)
Chemical type: Peptide from protein
Sequence: GGQIVGGVYVLPRRGPRL
Position: 27-44
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
MHC allele types: 54 413
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (73-90)
Chemical type: Peptide from protein
Sequence: GRSWAQPGYPWPLYGNEG
Position: 73-90
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
MHC allele types: 52 413 316 321
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (143-158)
Chemical type: Peptide from protein
Sequence: PVGGVARALAHGVRAL
Position: 143-158
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
MHC allele types: 414 419 54
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (143-158)
Chemical type: Peptide from protein
Sequence: PVGGVARALAHGVRAL
Position: 143-158
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (1513-1523)
Chemical type: Peptide from protein
Sequence: RPSGMFDSVVL
Position: 1513-1523
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (1791-1806)
Chemical type: Peptide from protein
Sequence: PAVASLMAFTASVTSPL
Position: 1791-1807
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
MHC allele types: 142 143 252 268 311 1 52 218 23 187 305 54 413
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (1824-1841)
Chemical type: Peptide from protein
Sequence: THLAGPQSSSAFVVSGLA
Position: 1824-1841
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
MHC allele types: 143 218 23 187 305 54 52
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (1918-1933)
Chemical type: Peptide from protein
Sequence: EGAVQWMNRLIAFASR
Position: 1916-1931
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
MHC allele types: 142 223 255 33 311 310 475 316
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (2946-2963)
Chemical type: Peptide from protein
Sequence: GKAKICGLYLFNWAVRTK
Position: 2946-2963
Source molecule (GenBank): ACZ60104.1
Assay category: TCell
Result: Positive
MHC allele types: 213 251 33 310 3 63 410
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (2965-2975)
Chemical type: Peptide from protein
Sequence: KLTPLPAAGQL
Position: 2965-2975
Source molecule (GenBank): ACZ60104.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (610-625)
Chemical type: Peptide from protein
Sequence: LTPRCMVDYPYRLWHY
Position: 609-624
Source molecule (GenBank): ACZ60112.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (696-712)
Chemical type: Peptide from protein
Sequence: LIHLHQNIVDVQYLYGV
Position: 695-711
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (696-712)
Chemical type: Peptide from protein
Sequence: LIHLHQNIVDVQYLYGV
Position: 695-711
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HCV (696-712)
Chemical type: Peptide from protein
Sequence: LIHLHQNIVDVQYLYGV
Position: 695-711
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HCV (702-719)
Chemical type: Peptide from protein
Sequence: NIVDVQYLYGVGSGMVGW
Position: 701-718
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (702-719)
Chemical type: Peptide from protein
Sequence: NIVDVQYLYGVGSGMVGW
Position: 701-718
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HCV (702-719)
Chemical type: Peptide from protein
Sequence: NIVDVQYLYGVGSGMVGW
Position: 701-718
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HCV (1198-1213)
Chemical type: Peptide from protein
Sequence: KALQFIPVETLSTQAR
Position: 1197-1212
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (1288-1305)
Chemical type: Peptide from protein
Sequence: GNRTVTTGAKLTYSTYGK
Position: 1287-1304
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (1423-1440)
Chemical type: Peptide from protein
Sequence: AYYRGLDVSVIPTAGDVV
Position: 1422-1439
Source molecule (GenBank): ACZ60112.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (1805-1822)
Chemical type: Peptide from protein
Sequence: TSPLTTNQTMFFNILGGW
Position: 1804-1821
Source molecule (GenBank): ACZ60112.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (2548-2565)
Chemical type: Peptide from protein
Sequence: NQIRSVWEDLLEDTTTPI
Position: 2547-2564
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (2603-2618)
Chemical type: Peptide from protein
Sequence: KRALYDVIQKLSIETM
Position: 2602-2617
Source molecule (GenBank): ACZ60105.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1a (73-90)
Chemical type: Peptide from protein
Sequence: GRTWAQPGYPWPLYGNEG
Position: 73-90
Source molecule (GenBank): ABW86969.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1a/b (143-158)
Chemical type: Peptide from protein
Sequence: GAPLGAVARALAHGVRVL
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1b (1423-1440)
Chemical type: Peptide from protein
Sequence: AYYRGLDVSVIPTIGDVV
Position: 1416-1433
Source molecule (GenBank): AAK08509.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1a/b (1513-1523)
Chemical type: Peptide from protein
Sequence: RPSGMFDSSVL
Position: 1507-1517
Source molecule (GenBank): AAK08509.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1a (1791-1807)
Chemical type: Peptide from protein
Sequence: PAIASLMAFTAAVTSPL
Position: 1785-1801
Source molecule (GenBank): ABV46054.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1a (2029-2046)
Chemical type: Peptide from protein
Sequence: IVHSTRHPCGESTAGHVK
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1a (2965-2975)
Chemical type: Peptide from protein
Sequence: VRTKLKLTPIAAAGRLDL
Position: 2950-2967
Source molecule (GenBank): ABW86969.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1b (73-90)
Chemical type: Peptide from protein
Sequence: GRAWAQPGYPWPLYGNEGL
Position: 73-91
Source molecule (GenBank): ABU97068.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1b (1791-1807)
Chemical type: Peptide from protein
Sequence: PAIASLMAFTASITSPL
Position: 1785-1801
Source molecule (GenBank): ABV46122.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1b (2029-2046)
Chemical type: Peptide from protein
Sequence: GIMQTTCPCGAQIAGHVK
Position: 2023-2040
Source molecule (GenBank): ABV46193.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1b (2965-2975)
Chemical type: Peptide from protein
Sequence: AVRTKLKLTPIPAASQL
Position: 2948-2964
Source molecule (GenBank): ABV46193.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 3a (2965-2975)
Chemical type: Peptide from protein
Sequence: AVRTKTKLTPLPAAGQL
Position: 2959-2975
Source molecule (GenBank): ACZ60104.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV  (1513-1529)
Chemical type: Peptide from protein
Sequence: RPSGMFDSVVLCECYDA
Position: 1513-1529
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV  (1513-1529)
Chemical type: Peptide from protein
Sequence: RPSGMFDSVVLCECYDA
Position: 1513-1529
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HCV  (1513-1529)
Chemical type: Peptide from protein
Sequence: RPSGMFDSVVLCECYDA
Position: 1513-1529
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HCV 3a (45-62)
Chemical type: Peptide from protein
Sequence: GVRATRKTSERSQPRGRR
Position: 45-62
Source molecule (GenBank): ACZ60112.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 3a (45-62)
Chemical type: Peptide from protein
Sequence: GVRATRKTSERSQPRGRR
Position: 45-62
Source molecule (GenBank): ACZ60112.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo