Reference: Helen Benham; Hendrik J Nel; Soi Cheng Law; Ahmed M Mehdi; Shayna Street; Nishta Ramnoruth; Helen Pahau; Bernett T Lee; Jennifer Ng; Marion E G Brunck; Claire Hyde; Leendert A Trouw; Nadine L Dudek; Anthony W Purcell; Brendan J O'Sullivan; John E Connolly; Sanjoy K Paul; Kim-Anh Lê Cao; Ranjeny Thomas. "Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype-positive rheumatoid arthritis patients." Science translational medicine (2015).

Epitope: Vim (447-455)-Cit450
Chemical type: Peptide from protein
Sequence: VETRDGQVI
Position: 447-455
Source molecule (GenBank): AAA61279.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Vim (447-455)-Cit450
Chemical type: Peptide from protein
Sequence: VETRDGQVI
Position: 447-455
Source molecule (GenBank): AAA61279.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Vim (447-455)-Cit450
Chemical type: Peptide from protein
Sequence: VETRDGQVI
Position: 447-455
Source molecule (GenBank): AAA61279.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 50000.0

Epitope: Vim (447-455)-Cit450
Chemical type: Peptide from protein
Sequence: VETRDGQVI
Position: 447-455
Source molecule (GenBank): AAA61279.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 50000.0

Epitope: Vim (447-455)-Cit450
Chemical type: Peptide from protein
Sequence: VETRDGQVI
Position: 447-455
Source molecule (GenBank): AAA61279.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 50000.0

Epitope: Col II (1237-1249)-Cit1240
Chemical type: Peptide from protein
Sequence: QYMRADQAAGGLR
Position: 1237-1249
Source molecule (GenBank): AAC41772.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Col II (1237-1249)-Cit1240
Chemical type: Peptide from protein
Sequence: QYMRADQAAGGLR
Position: 1237-1249
Source molecule (GenBank): AAC41772.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Col II (1237-1249)-Cit1240
Chemical type: Peptide from protein
Sequence: QYMRADQAAGGLR
Position: 1237-1249
Source molecule (GenBank): AAC41772.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 50000.0

Epitope: Col II (1237-1249)-Cit1240
Chemical type: Peptide from protein
Sequence: QYMRADQAAGGLR
Position: 1237-1249
Source molecule (GenBank): AAC41772.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 50000.0

Epitope: Col II (1237-1249)-Cit1240
Chemical type: Peptide from protein
Sequence: QYMRADQAAGGLR
Position: 1237-1249
Source molecule (GenBank): AAC41772.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 50000.0

Epitope: Agg (84-103)-Cit93
Chemical type: Peptide from protein
Sequence: VVLLVATEGRVRVNSAYQDK
Position: 84-103
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Vim (1-16) Cit3
Chemical type: Peptide from protein
Sequence: STRSVSSSSYRRMFGG
Position: 2-17
Source molecule (GenBank): AAA61279.1
Assay category: BCell
Result: Positive

Epitope: Vim (59-74) Cit64
Chemical type: Peptide from protein
Sequence: GVYATRSSAVRLRSSV
Position: 59-74
Source molecule (GenBank): AAA61279.1
Assay category: BCell
Result: Positive

Epitope: Eno (5-20) Cit9
Chemical type: Peptide from protein
Sequence: KIWAREILDSRGNPTV
Position: 5-20
Source molecule (GenBank): AAB51320.1
Assay category: BCell
Result: Positive

Epitope: Fib beta (36-52) Cit44
Chemical type: Peptide from protein
Sequence: NEEGFFSARGHRPLDKK
Position: 36-52
Source molecule (GenBank): AAA52445.1
Assay category: BCell
Result: Positive

Epitope: Vim (447-455)
Chemical type: Peptide from protein
Sequence: VETRDGQVI
Position: 447-455
Source molecule (GenBank): AAA61279.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Vim (447-455)
Chemical type: Peptide from protein
Sequence: VETRDGQVI
Position: 447-455
Source molecule (GenBank): AAA61279.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Vim (447-455)
Chemical type: Peptide from protein
Sequence: VETRDGQVI
Position: 447-455
Source molecule (GenBank): AAA61279.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Fib alpha (27-43)
Chemical type: Peptide from protein
Sequence: LTQQGSVLR
Assay category: MhcLigandElution
Result: Positive

Epitope: Fib alpha (27-43)
Chemical type: Peptide from protein
Sequence: LTQQGSVLR
Assay category: MhcLigandElution
Result: Positive

Epitope: Fib alpha (27-43)
Chemical type: Peptide from protein
Sequence: LTQQGSVLR
Assay category: MhcLigandElution
Result: Positive

Epitope: Fib beta (433-441)
Chemical type: Peptide from protein
Sequence: WYNQCHAAN
Assay category: MhcLigandElution
Result: Positive-Low

Epitope: Fib beta (433-441)
Chemical type: Peptide from protein
Sequence: WYNQCHAAN
Assay category: MhcLigandElution
Result: Positive-Low

Epitope: Fib beta (433-441)
Chemical type: Peptide from protein
Sequence: WYNQCHAAN
Assay category: MhcLigandElution
Result: Positive-Low

Epitope: Vim (66-78)
Chemical type: Peptide from protein
Sequence: SAVRAQSSVPGVR
Assay category: MhcLigandElution
Result: Positive

Epitope: Vim (66-78)
Chemical type: Peptide from protein
Sequence: SAVRAQSSVPGVR
Assay category: MhcLigandElution
Result: Positive

Epitope: Vim (66-78)
Chemical type: Peptide from protein
Sequence: SAVRAQSSVPGVR
Assay category: MhcLigandElution
Result: Positive

Epitope: Fib (433-441) Cit436
Chemical type: Peptide from protein
Sequence: WYNRCHAAN
Position: 433-441
Source molecule (GenBank): NP_005132.2
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 50000.0

Epitope: Fib (433-441) Cit436
Chemical type: Peptide from protein
Sequence: WYNRCHAAN
Position: 433-441
Source molecule (GenBank): NP_005132.2
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 50000.0

Epitope: Fib (433-441) Cit436
Chemical type: Peptide from protein
Sequence: WYNRCHAAN
Position: 433-441
Source molecule (GenBank): NP_005132.2
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 50000.0