Reference: R Raju; E G Spack; C S David. "Acetylcholine receptor peptide recognition in HLA DR3-transgenic mice: in vivo responses correlate with MHC-peptide binding." Journal of immunology (Baltimore, Md. : 1950) (2001).

Epitope: Human AChRα1-20
Chemical type: Peptide from protein
Sequence: SEHETRLVAKLFKDYSSVVR
Position: 21-40
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα11-30
Chemical type: Peptide from protein
Sequence: LFKDYSSVVRPVEDHRQVVE
Position: 31-50
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα21-40
Chemical type: Peptide from protein
Sequence: PVEDHRQVVEVTVGLQLIQL
Position: 41-60
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα31-50
Chemical type: Peptide from protein
Sequence: VTVGLQLIQLINVDEVNQIV
Position: 51-70
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα41-60
Chemical type: Peptide from protein
Sequence: INVDEVNQIVTTNVRLKQQW
Position: 61-80
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα51-70
Chemical type: Peptide from protein
Sequence: TTNVRLKQQWVDYNLKWNPD
Position: 71-90
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα61-80
Chemical type: Peptide from protein
Sequence: VDYNLKWNPDDYGGVKKIHI
Position: 81-100
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα71-90
Chemical type: Peptide from protein
Sequence: DYGGVKKIHIPSEKIWRPDL
Position: 91-110
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα81-100
Chemical type: Peptide from protein
Sequence: PSEKIWRPDLVLYNNADGDF
Position: 101-120
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα91-110
Chemical type: Peptide from protein
Sequence: VLYNNADGDFAIVKFTKVLL
Position: 111-130
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα111-130
Chemical type: Peptide from protein
Sequence: QYTGHITWTPPAIFKSYCEI
Position: 131-150
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα121-140
Chemical type: Peptide from protein
Sequence: PAIFKSYCEIIVTHFPFDEQ
Position: 141-160
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα131-150
Chemical type: Peptide from protein
Sequence: IVTHFPFDEQNCSMKLGTWT
Position: 151-170
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα149-158
Chemical type: Peptide from protein
Sequence: WTYDGSVVAI
Position: 169-178
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα151-170
Chemical type: Peptide from protein
Sequence: YDGSVVAINPESDQPDLSNF
Position: 171-190
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα161-180
Chemical type: Peptide from protein
Sequence: ESDQPDLSNFMESGEWVIKE
Position: 181-200
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα175-186
Chemical type: Peptide from protein
Sequence: EWVIKESRGWKH
Position: 195-206
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα175-186
Chemical type: Peptide from protein
Sequence: EWVIKESRGWKH
Position: 195-206
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα191-210
Chemical type: Peptide from protein
Sequence: SCCPDTPYLDITYHFVMQRL
Position: 211-230
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Mouse AChRα171-190
Chemical type: Peptide from protein
Sequence: MESGEWVIKEARGWKHWVFY
Position: 191-210
Source molecule (GenBank): AAB53942.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: hAChRα1-14
Chemical type: Peptide from protein
Sequence: SEHETRLVAKLFKD
Position: 21-34
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα8-21
Chemical type: Peptide from protein
Sequence: VAKLFKDYSSVVRP
Position: 28-41
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα15-28
Chemical type: Peptide from protein
Sequence: YSSVVRPVEDHRQV
Position: 35-48
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα19-34
Chemical type: Peptide from protein
Sequence: VRPVEDHRQVVEVTVG
Position: 39-54
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα22-35
Chemical type: Peptide from protein
Sequence: VEDHRQVVEVTVGL
Position: 42-55
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα27-42
Chemical type: Peptide from protein
Sequence: QVVEVTVGLQLIQLIN
Position: 47-62
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 13270.0

Epitope: hAChRα36-49
Chemical type: Peptide from protein
Sequence: QLIQLINVDEVNQI
Position: 56-69
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 7299.0

Epitope: hAChRα48-67
Chemical type: Peptide from protein
Sequence: QIVTTNVRLKQQWVDYNLKW
Position: 68-87
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα50-63
Chemical type: Peptide from protein
Sequence: VTTNVRLKQQWVDY
Position: 70-83
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα57-70
Chemical type: Peptide from protein
Sequence: KQQWVDYNLKWNPD
Position: 77-90
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα64-77
Chemical type: Peptide from protein
Sequence: NLKWNPDDYGGVKK
Position: 84-97
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα71-84
Chemical type: Peptide from protein
Sequence: DYGGVKKIHIPSEK
Position: 91-104
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα78-91
Chemical type: Peptide from protein
Sequence: IHIPSEKIWRPDLV
Position: 98-111
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα85-98
Chemical type: Peptide from protein
Sequence: IWRPDLVLYNNADG
Position: 105-118
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα92-105
Chemical type: Peptide from protein
Sequence: LYNNADGDFAIVKF
Position: 112-125
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα99-112
Chemical type: Peptide from protein
Sequence: DFAIVKFTKVLLQY
Position: 119-132
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 34183.0

Epitope: hAChRα113-126
Chemical type: Peptide from protein
Sequence: TGHITWTPPAIFKS
Position: 133-146
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 72956.0

Epitope: hAChRα120-133
Chemical type: Peptide from protein
Sequence: PPAIFKSYCEIIVT
Position: 140-153
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα127-140
Chemical type: Peptide from protein
Sequence: YCEIIVTHFPFDEQ
Position: 147-160
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα134-147
Chemical type: Peptide from protein
Sequence: HFPFDEQNCSMKLG
Position: 154-167
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα141-154
Chemical type: Peptide from protein
Sequence: NCSMKLGTWTYDGS
Position: 161-174
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα144-163
Chemical type: Peptide from protein
Sequence: MKLGTWTYDGSVVAINPESD
Position: 164-183
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2002.0

Epitope: hAChRα162-175
Chemical type: Peptide from protein
Sequence: SDQPDLSNFMESGE
Position: 182-195
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα169-182
Chemical type: Peptide from protein
Sequence: NFMESGEWVIKESR
Position: 189-202
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα176-189
Chemical type: Peptide from protein
Sequence: WVIKESRGWKHSVT
Position: 196-209
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα181-195
Chemical type: Peptide from protein
Sequence: SRGWKHSVTYSCCPDTPY
Position: 201-218
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα183-196
Chemical type: Peptide from protein
Sequence: GWKHSVTYSCCPDT
Position: 203-216
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα190-203
Chemical type: Peptide from protein
Sequence: YSCCPDTPYLDITY
Position: 210-223
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: hAChRα195-212
Chemical type: Peptide from protein
Sequence: DTPYLDITYHFVMQRLPL
Position: 215-232
Source molecule (GenBank): AAD14247.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 6036.0

Epitope: Human AChRα151-160
Chemical type: Peptide from protein
Sequence: YDGSVVAINP
Position: 171-180
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα151-160
Chemical type: Peptide from protein
Sequence: YDGSVVAINP
Position: 171-180
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα171-180
Chemical type: Peptide from protein
Sequence: MESGEWVIKE
Position: 191-200
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Human AChRα171-180
Chemical type: Peptide from protein
Sequence: MESGEWVIKE
Position: 191-200
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo