Reference: Jeremy Loyau; Thierry Monney; Marco Montefiori; Fedir Bokhovchuk; Jeremy Streuli; Matthew Blackburn; Arnaud Goepfert; Lydia N Caro; Samitabh Chakraborti; Stefania De Angelis; Camille Grandclément; Stanislas Blein; M Lamine Mbow; Ankita Srivastava; Mario Perro; Stefano Sammicheli; Eugene A Zhukovsky; Michael Dyson; Cyrille Dreyfus. "Biparatopic binding of ISB 1442 to CD38 in trans enables increased cell antibody density and increased avidity." mAbs (2025).

Epitope: Epitope of Fab B6-D9 on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: D202, H228, Q231, P232, E233, K234, V235, Q236, S267, K268, R269, N270
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive
Quantitative measurement: 10.0

Epitope: Epitope of Fab B6-D9 on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: D202, H228, Q231, P232, E233, K234, V235, Q236, S267, K268, R269, N270
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of Fab B6-D9 on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: D202, H228, Q231, P232, E233, K234, V235, Q236, S267, K268, R269, N270
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab B6-D9 on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: D202, H228, Q231, P232, E233, K234, V235, Q236, S267, K268, R269, N270
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive
Quantitative measurement: 1.84

Epitope: Epitope of Fab B6-D9 on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: D202, H228, Q231, P232, E233, K234, V235, Q236, S267, K268, R269, N270
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.6

Epitope: Epitope of Fab B6-D9 on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: D202, H228, Q231, P232, E233, K234, V235, Q236, S267, K268, R269, N270
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000077

Epitope: Epitope of Fab B6-D9 on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: D202, H228, Q231, P232, E233, K234, V235, Q236, S267, K268, R269, N270
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00015

Epitope: Epitope of Fab B6-D9 on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: D202, H228, Q231, P232, E233, K234, V235, Q236, S267, K268, R269, N270
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive
Quantitative measurement: 1.4

Epitope: Epitope of Fab B6-D9 on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: D202, H228, Q231, P232, E233, K234, V235, Q236, S267, K268, R269, N270
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive
Quantitative measurement: 11.0

Epitope: Epitope of Fab E2-RecA on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: L64, A65, V68, K69, E72, I73, P75, R78, H79, V80, D81, C82
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab E2-RecA on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: L64, A65, V68, K69, E72, I73, P75, R78, H79, V80, D81, C82
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab E2-RecA on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: L64, A65, V68, K69, E72, I73, P75, R78, H79, V80, D81, C82
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000051

Epitope: Epitope of Fab E2-RecA on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: L64, A65, V68, K69, E72, I73, P75, R78, H79, V80, D81, C82
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2.7

Epitope: Epitope of Fab E2-RecA on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: L64, A65, V68, K69, E72, I73, P75, R78, H79, V80, D81, C82
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive
Quantitative measurement: 9.0

Epitope: Epitope of Fab E2-RecA on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: L64, A65, V68, K69, E72, I73, P75, R78, H79, V80, D81, C82
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000052

Epitope: Epitope of Fab E2-RecA on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: L64, A65, V68, K69, E72, I73, P75, R78, H79, V80, D81, C82
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2.7

Epitope: Epitope of Fab E2-RecA on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: L64, A65, V68, K69, E72, I73, P75, R78, H79, V80, D81, C82
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive
Quantitative measurement: 14.0

Epitope: Epitope of Fab E2-RecA on hCD38
Chemical type: Discontinuous protein residues
Discontinuous residues: L64, A65, V68, K69, E72, I73, P75, R78, H79, V80, D81, C82
Source molecule (GenBank): P28907.2
Assay category: BCell
Result: Positive
Quantitative measurement: 1.6