Reference: Junbao Yang; Eddie James; Michelle Roti; Laurie Huston; John A Gebe; William W Kwok. "Searching immunodominant epitopes prior to epidemic: HLA class II-restricted SARS-CoV spike protein epitopes in unexposed individuals." International immunology (2009).

Epitope: p7 (45-62)
Chemical type: Peptide from protein
Sequence: EIFRSDTLYLTQDLFLPF
Position: 45-62
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p8 (53-70)
Chemical type: Peptide from protein
Sequence: YLTQDLFLPFYSNVTGFH
Position: 53-70
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p10 (67-84)
Chemical type: Peptide from protein
Sequence: TGFHTINHTFGNPVIPFK
Position: 67-84
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p14 (98-115)
Chemical type: Peptide from protein
Sequence: VRGWVFGSTMNNKSQSVI
Position: 98-115
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p14 (98-115)
Chemical type: Peptide from protein
Sequence: VRGWVFGSTMNNKSQSVI
Position: 98-115
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p14 (98-115)
Chemical type: Peptide from protein
Sequence: VRGWVFGSTMNNKSQSVI
Position: 98-115
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p19 (135-152)
Chemical type: Peptide from protein
Sequence: NPFFAVSKPMGTQTHTMI
Position: 135-152
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p22 (159-171)
Chemical type: Peptide from protein
Sequence: CTFEYISDAFSLD
Position: 159-171
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p22 (159-171)
Chemical type: Peptide from protein
Sequence: CTFEYISDAFSLD
Position: 159-171
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p22 (159-171)
Chemical type: Peptide from protein
Sequence: CTFEYISDAFSLD
Position: 159-171
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p23 (166-178)
Chemical type: Peptide from protein
Sequence: DAFSLDVSEKSGN
Position: 166-178
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p23 (166-178)
Chemical type: Peptide from protein
Sequence: DAFSLDVSEKSGN
Position: 166-178
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p23 (166-178)
Chemical type: Peptide from protein
Sequence: DAFSLDVSEKSGN
Position: 166-178
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p23 (166-178)
Chemical type: Peptide from protein
Sequence: DAFSLDVSEKSGN
Position: 166-178
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p23 (166-178)
Chemical type: Peptide from protein
Sequence: DAFSLDVSEKSGN
Position: 166-178
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p23 (166-178)
Chemical type: Peptide from protein
Sequence: DAFSLDVSEKSGN
Position: 166-178
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p23 (166-178)
Chemical type: Peptide from protein
Sequence: DAFSLDVSEKSGN
Position: 166-178
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p30 (215-232)
Chemical type: Peptide from protein
Sequence: TLKPIFKLPLGINITNFR
Position: 215-232
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p32 (229-245)
Chemical type: Peptide from protein
Sequence: TNFRAILTAFSPAQDIW
Position: 229-245
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p32 (229-245)
Chemical type: Peptide from protein
Sequence: TNFRAILTAFSPAQDIW
Position: 229-245
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p32 (229-245)
Chemical type: Peptide from protein
Sequence: TNFRAILTAFSPAQDIW
Position: 229-245
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p33 (236-253)
Chemical type: Peptide from protein
Sequence: TAFSPAQDIWGTSAAAYF
Position: 236-253
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p39 (278-295)
Chemical type: Peptide from protein
Sequence: CSQNPLAELKCSVKSFEI
Position: 278-295
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p39 (278-295)
Chemical type: Peptide from protein
Sequence: CSQNPLAELKCSVKSFEI
Position: 278-295
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p41 (291-308)
Chemical type: Peptide from protein
Sequence: KSFEIDKGIYQTSNFRVV
Position: 291-308
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p41 (291-308)
Chemical type: Peptide from protein
Sequence: KSFEIDKGIYQTSNFRVV
Position: 291-308
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p41 (291-308)
Chemical type: Peptide from protein
Sequence: KSFEIDKGIYQTSNFRVV
Position: 291-308
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p42 (299-316)
Chemical type: Peptide from protein
Sequence: IYQTSNFRVVPSGDVVRF
Position: 299-316
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p48 (343-360)
Chemical type: Peptide from protein
Sequence: KKISNCVADYSVLYNSTF
Position: 343-360
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p48 (343-360)
Chemical type: Peptide from protein
Sequence: KKISNCVADYSVLYNSTF
Position: 343-360
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p50 (358-374)
Chemical type: Peptide from protein
Sequence: STFFSTFKCYGVSATKL
Position: 358-374
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p62 (449-461)
Chemical type: Peptide from protein
Sequence: RPFERDISNVPFS
Position: 449-461
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p62 (449-461)
Chemical type: Peptide from protein
Sequence: RPFERDISNVPFS
Position: 449-461
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p62 (449-461)
Chemical type: Peptide from protein
Sequence: RPFERDISNVPFS
Position: 449-461
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p62 (449-461)
Chemical type: Peptide from protein
Sequence: RPFERDISNVPFS
Position: 449-461
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p62 (449-461)
Chemical type: Peptide from protein
Sequence: RPFERDISNVPFS
Position: 449-461
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p62 (449-461)
Chemical type: Peptide from protein
Sequence: RPFERDISNVPFS
Position: 449-461
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p62 (449-461)
Chemical type: Peptide from protein
Sequence: RPFERDISNVPFS
Position: 449-461
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p91 (665-681)
Chemical type: Peptide from protein
Sequence: LLRSTSQKSIVAYTMSL
Position: 665-681
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p92 (672-689)
Chemical type: Peptide from protein
Sequence: KSIVAYTMSLGADSSIAY
Position: 672-689
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p92 (672-689)
Chemical type: Peptide from protein
Sequence: KSIVAYTMSLGADSSIAY
Position: 672-689
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p105 (767-784)
Chemical type: Peptide from protein
Sequence: VKQMYKTPTLKYFGGFNF
Position: 767-784
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p105 (767-784)
Chemical type: Peptide from protein
Sequence: VKQMYKTPTLKYFGGFNF
Position: 767-784
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p111 (814-831)
Chemical type: Peptide from protein
Sequence: GFMKQYGECLGDINARDL
Position: 814-831
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p111 (814-831)
Chemical type: Peptide from protein
Sequence: GFMKQYGECLGDINARDL
Position: 814-831
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p114 (834-851)
Chemical type: Peptide from protein
Sequence: AQKFNGLTVLPPLLTDDM
Position: 834-851
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p119 (873-888)
Chemical type: Peptide from protein
Sequence: GAALQIPFAMQMAYRF
Position: 873-888
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p121 (884-899)
Chemical type: Peptide from protein
Sequence: MAYRFNGIGVTQNVLY
Position: 884-899
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p121 (884-899)
Chemical type: Peptide from protein
Sequence: MAYRFNGIGVTQNVLY
Position: 884-899
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p121 (884-899)
Chemical type: Peptide from protein
Sequence: MAYRFNGIGVTQNVLY
Position: 884-899
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p126 (918-934)
Chemical type: Peptide from protein
Sequence: ESLTTTSTALGKLQDVV
Position: 918-934
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Negative
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p126 (918-934)
Chemical type: Peptide from protein
Sequence: ESLTTTSTALGKLQDVV
Position: 918-934
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p126 (918-934)
Chemical type: Peptide from protein
Sequence: ESLTTTSTALGKLQDVV
Position: 918-934
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p126 (918-934)
Chemical type: Peptide from protein
Sequence: ESLTTTSTALGKLQDVV
Position: 918-934
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p129 (939-955)
Chemical type: Peptide from protein
Sequence: QALNTLVKQLSSNFGAI
Position: 939-955
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p136 (993-1010)
Chemical type: Peptide from protein
Sequence: QLIRAAEIRASANLAATK
Position: 993-1010
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p136 (993-1010)
Chemical type: Peptide from protein
Sequence: QLIRAAEIRASANLAATK
Position: 993-1010
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Negative
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p136 (993-1010)
Chemical type: Peptide from protein
Sequence: QLIRAAEIRASANLAATK
Position: 993-1010
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p136 (993-1010)
Chemical type: Peptide from protein
Sequence: QLIRAAEIRASANLAATK
Position: 993-1010
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: p61 (442-459)
Chemical type: Peptide from protein
Sequence: YLRHGKLRPFERDISNVP
Position: 442-459
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p61 (442-459)
Chemical type: Peptide from protein
Sequence: YLRHGKLRPFERDISNVP
Position: 442-459
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: p61 (442-459)
Chemical type: Peptide from protein
Sequence: YLRHGKLRPFERDISNVP
Position: 442-459
Source molecule (GenBank): ABF65836.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated