Reference: José-Manuel Rojas; Teresa Rodríguez-Calvo; Lourdes Peña; Noemí Sevilla. "T cell responses to bluetongue virus are directed against multiple and identical CD4+ and CD8+ T cell epitopes from the VP7 core protein in mouse and sheep." Vaccine (2011).

Epitope: VP7(139)
Chemical type: Peptide from protein
Sequence: GRWFMRAAQAVTAVV
Position: 139-153
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host: F 3 months
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: VP7(139)
Chemical type: Peptide from protein
Sequence: GRWFMRAAQAVTAVV
Position: 139-153
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VP7(139)
Chemical type: Peptide from protein
Sequence: GRWFMRAAQAVTAVV
Position: 139-153
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VP7(324)
Chemical type: Peptide from protein
Sequence: RPEFAIHGVNPMPGP
Position: 324-338
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VP7(324)
Chemical type: Peptide from protein
Sequence: RPEFAIHGVNPMPGP
Position: 324-338
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host: F 3 months
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: VP7(324)
Chemical type: Peptide from protein
Sequence: RPEFAIHGVNPMPGP
Position: 324-338
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VP7(324)
Chemical type: Peptide from protein
Sequence: RPEFAIHGVNPMPGP
Position: 324-338
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VP7(181)
Chemical type: Peptide from protein
Sequence: PMMIYLVWRRIENFA
Position: 181-195
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VP7(181)
Chemical type: Peptide from protein
Sequence: PMMIYLVWRRIENFA
Position: 181-195
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VP7(72)
Chemical type: Peptide from protein
Sequence: AAGINVGPI
Position: 72-80
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VP7(72)
Chemical type: Peptide from protein
Sequence: AAGINVGPI
Position: 72-80
Source molecule (GenBank): ACJ06230.1
Assay category: MhcBinding
Result: Positive-High

Epitope: VP7(283)
Chemical type: Peptide from protein
Sequence: TAILNRTTL
Position: 283-291
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host: F 3 months
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: VP7(283)
Chemical type: Peptide from protein
Sequence: TAILNRTTL
Position: 283-291
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: VP7(283)
Chemical type: Peptide from protein
Sequence: TAILNRTTL
Position: 283-291
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VP7(283)
Chemical type: Peptide from protein
Sequence: TAILNRTTL
Position: 283-291
Source molecule (GenBank): ACJ06230.1
Assay category: MhcBinding
Result: Positive-High

Epitope: VP7(327)
Chemical type: Peptide from protein
Sequence: FAIHGVNPM
Position: 327-335
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: VP7(327)
Chemical type: Peptide from protein
Sequence: FAIHGVNPM
Position: 327-335
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VP7(327)
Chemical type: Peptide from protein
Sequence: FAIHGVNPM
Position: 327-335
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host: F 3 months
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: VP7(327)
Chemical type: Peptide from protein
Sequence: FAIHGVNPM
Position: 327-335
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VP7(327)
Chemical type: Peptide from protein
Sequence: FAIHGVNPM
Position: 327-335
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VP7(327)
Chemical type: Peptide from protein
Sequence: FAIHGVNPM
Position: 327-335
Source molecule (GenBank): ACJ06230.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: VP7(327)
Chemical type: Peptide from protein
Sequence: FAIHGVNPM
Position: 327-335
Source molecule (GenBank): ACJ06230.1
Assay category: MhcBinding
Result: Negative

Epitope: VP7(35)
Chemical type: Peptide from protein
Sequence: IAINRYNGL
Position: 35-43
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VP7(35)
Chemical type: Peptide from protein
Sequence: IAINRYNGL
Position: 35-43
Source molecule (GenBank): ACJ06230.1
Assay category: MhcBinding
Result: Positive-High

Epitope: VP7(80)
Chemical type: Peptide from protein
Sequence: ISPDYTQHM
Position: 80-88
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host: F 3 months
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: VP7(80)
Chemical type: Peptide from protein
Sequence: ISPDYTQHM
Position: 80-88
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: VP7(80)
Chemical type: Peptide from protein
Sequence: ISPDYTQHM
Position: 80-88
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VP7(80)
Chemical type: Peptide from protein
Sequence: ISPDYTQHM
Position: 80-88
Source molecule (GenBank): ACJ06230.1
Assay category: MhcBinding
Result: Positive-High

Epitope: VP7(245)
Chemical type: Peptide from protein
Sequence: IQVVFYISM
Position: 245-253
Source molecule (GenBank): ACJ06230.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: VP7(245)
Chemical type: Peptide from protein
Sequence: IQVVFYISM
Position: 245-253
Source molecule (GenBank): ACJ06230.1
Assay category: MhcBinding
Result: Negative

Epitope: VP7(245)
Chemical type: Peptide from protein
Sequence: IQVVFYISM
Position: 245-253
Source molecule (GenBank): ACJ06230.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: gp(33–41)
Chemical type: Peptide from protein
Sequence: KAVYNFATC
Position: 33-41
Source molecule (GenBank): ABI96818.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: gp(33–41)
Chemical type: Peptide from protein
Sequence: KAVYNFATC
Position: 33-41
Source molecule (GenBank): ABI96818.1
Assay category: MhcBinding
Result: Positive-Intermediate