Reference: Dmitry V Shcheblyakov; Irina A Favorskaya; Inna V Dolzhikova; Anastasia I Korobkova; Irina A Alekseeva; Ilias B Esmagambetov; Olga L Voronina; Amir I Tukhvatulin; Olga V Zubkova; Artem A Derkaev; Ekaterina I Ryabova; Anna A Iliukhina; Ilia D Zorkov; Daria M Grousova; Dmitriy A Reshetnikov; Natalia N Ryzhova; Ekaterina I Ermolova; Marina S Kunda; Ilya O Matyuta; Konstantin M Boyko; Vladimir O Popov; Denis Y Logunov; Nikolai N Sluchanko; Alexander L Gintsburg. "Ultra-potent RBM-specific single-domain antibody broadly neutralizes multiple SARS-CoV-2 variants with picomolar activity." International journal of biological macromolecules (2025).

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.731

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.55

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.244

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody 1p1B10 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V445, G446, G447, Y449, N450, L452, F456, V483, E484, G485, F486, C488, Y489, F490, L492, Q493, S494, Q498, T500, N501
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive