Reference: P Daniel Warren; Terry H Landowski; Mark S Dodson; Adnan Gulzar; John D Palting; Erika Walker; Penny Towne; Margaret H Smith. "Paratope plasticity determines anti-HER2 (4B5) antibody specificity." mAbs (2025).

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive
Quantitative measurement: 625.0

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive
Quantitative measurement: 32.0

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0086

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 198.0

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.3

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2600000.0

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.7

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2
Chemical type: Peptide from protein
Sequence: GTPTAENPEYLGLDVPV
Position: 1239-1255
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 198.0

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive
Quantitative measurement: 625.0

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive
Quantitative measurement: 32.0

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.7

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 198.0

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 198.0

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive

Epitope: HER4
Chemical type: Peptide from protein
Sequence: RPIVAENPEYLSEFSLK
Position: 1275-1291
Source molecule (GenBank): Q15303.1
Assay category: BCell
Result: Positive

Epitope: HER2 target 2
Chemical type: Peptide from protein
Sequence: FGGAVENPEYLTPQGGA
Position: 1187-1203
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2 target 2
Chemical type: Peptide from protein
Sequence: FGGAVENPEYLTPQGGA
Position: 1187-1203
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2 target 2
Chemical type: Peptide from protein
Sequence: FGGAVENPEYLTPQGGA
Position: 1187-1203
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2 target 2
Chemical type: Peptide from protein
Sequence: FGGAVENPEYLTPQGGA
Position: 1187-1203
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2 target 2
Chemical type: Peptide from protein
Sequence: FGGAVENPEYLTPQGGA
Position: 1187-1203
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2 target 2
Chemical type: Peptide from protein
Sequence: FGGAVENPEYLTPQGGA
Position: 1187-1203
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2 target 2
Chemical type: Peptide from protein
Sequence: FGGAVENPEYLTPQGGA
Position: 1187-1203
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2 target 2
Chemical type: Peptide from protein
Sequence: FGGAVENPEYLTPQGGA
Position: 1187-1203
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2 target 2
Chemical type: Peptide from protein
Sequence: FGGAVENPEYLTPQGGA
Position: 1187-1203
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2 target 2
Chemical type: Peptide from protein
Sequence: FGGAVENPEYLTPQGGA
Position: 1187-1203
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: HER2 target 2
Chemical type: Peptide from protein
Sequence: FGGAVENPEYLTPQGGA
Position: 1187-1203
Source molecule (GenBank): P04626.1
Assay category: BCell
Result: Positive

Epitope: ZSCAN18
Chemical type: Peptide from protein
Sequence: LKSFPEDPQHLGEWGHL
Position: 216-232
Source molecule (GenBank): Q8TBC5.2
Assay category: BCell
Result: Positive

Epitope: ZSCAN18
Chemical type: Peptide from protein
Sequence: LKSFPEDPQHLGEWGHL
Position: 216-232
Source molecule (GenBank): Q8TBC5.2
Assay category: BCell
Result: Positive

Epitope: ZSCAN18
Chemical type: Peptide from protein
Sequence: LKSFPEDPQHLGEWGHL
Position: 216-232
Source molecule (GenBank): Q8TBC5.2
Assay category: BCell
Result: Positive

Epitope: ZSCAN18
Chemical type: Peptide from protein
Sequence: LKSFPEDPQHLGEWGHL
Position: 216-232
Source molecule (GenBank): Q8TBC5.2
Assay category: BCell
Result: Positive

Epitope: ZSCAN18
Chemical type: Peptide from protein
Sequence: LKSFPEDPQHLGEWGHL
Position: 216-232
Source molecule (GenBank): Q8TBC5.2
Assay category: BCell
Result: Positive

Epitope: ZSCAN18
Chemical type: Peptide from protein
Sequence: LKSFPEDPQHLGEWGHL
Position: 216-232
Source molecule (GenBank): Q8TBC5.2
Assay category: BCell
Result: Positive-Low

Epitope: ZSCAN18
Chemical type: Peptide from protein
Sequence: LKSFPEDPQHLGEWGHL
Position: 216-232
Source molecule (GenBank): Q8TBC5.2
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 198.0

Epitope: ZSCAN18
Chemical type: Peptide from protein
Sequence: LKSFPEDPQHLGEWGHL
Position: 216-232
Source molecule (GenBank): Q8TBC5.2
Assay category: BCell
Result: Positive

Epitope: ZSCAN18
Chemical type: Peptide from protein
Sequence: LKSFPEDPQHLGEWGHL
Position: 216-232
Source molecule (GenBank): Q8TBC5.2
Assay category: BCell
Result: Positive

Epitope: ZSCAN18
Chemical type: Peptide from protein
Sequence: LKSFPEDPQHLGEWGHL
Position: 216-232
Source molecule (GenBank): Q8TBC5.2
Assay category: BCell
Result: Positive

Epitope: AKR1B10
Chemical type: Peptide from protein
Sequence: PWAKPEDPSLLEDPKIK
Position: 219-235
Source molecule (GenBank): O60218.2
Assay category: BCell
Result: Positive

Epitope: AKR1B10
Chemical type: Peptide from protein
Sequence: PWAKPEDPSLLEDPKIK
Position: 219-235
Source molecule (GenBank): O60218.2
Assay category: BCell
Result: Positive

Epitope: AKR1B10
Chemical type: Peptide from protein
Sequence: PWAKPEDPSLLEDPKIK
Position: 219-235
Source molecule (GenBank): O60218.2
Assay category: BCell
Result: Positive

Epitope: AKR1B10
Chemical type: Peptide from protein
Sequence: PWAKPEDPSLLEDPKIK
Position: 219-235
Source molecule (GenBank): O60218.2
Assay category: BCell
Result: Positive-Low

Epitope: AKR1B10
Chemical type: Peptide from protein
Sequence: PWAKPEDPSLLEDPKIK
Position: 219-235
Source molecule (GenBank): O60218.2
Assay category: BCell
Result: Positive
Quantitative measurement: 625.0

Epitope: AKR1B10
Chemical type: Peptide from protein
Sequence: PWAKPEDPSLLEDPKIK
Position: 219-235
Source molecule (GenBank): O60218.2
Assay category: BCell
Result: Positive

Epitope: AKR1B10
Chemical type: Peptide from protein
Sequence: PWAKPEDPSLLEDPKIK
Position: 219-235
Source molecule (GenBank): O60218.2
Assay category: BCell
Result: Positive

Epitope: AKR1B10
Chemical type: Peptide from protein
Sequence: PWAKPEDPSLLEDPKIK
Position: 219-235
Source molecule (GenBank): O60218.2
Assay category: BCell
Result: Positive

Epitope: AKR1B10
Chemical type: Peptide from protein
Sequence: PWAKPEDPSLLEDPKIK
Position: 219-235
Source molecule (GenBank): O60218.2
Assay category: BCell
Result: Positive

Epitope: AKR1B10
Chemical type: Peptide from protein
Sequence: PWAKPEDPSLLEDPKIK
Position: 219-235
Source molecule (GenBank): O60218.2
Assay category: BCell
Result: Positive

Epitope: AKR1B10
Chemical type: Peptide from protein
Sequence: PWAKPEDPSLLEDPKIK
Position: 219-235
Source molecule (GenBank): O60218.2
Assay category: BCell
Result: Positive

Epitope: TITIN
Chemical type: Peptide from protein
Sequence: VKVTAENPEGVIEHKVK
Position: 1910-1926
Source molecule (GenBank): Q8WZ42.4
Assay category: BCell
Result: Positive

Epitope: TITIN
Chemical type: Peptide from protein
Sequence: VKVTAENPEGVIEHKVK
Position: 1910-1926
Source molecule (GenBank): Q8WZ42.4
Assay category: BCell
Result: Positive

Epitope: TITIN
Chemical type: Peptide from protein
Sequence: VKVTAENPEGVIEHKVK
Position: 1910-1926
Source molecule (GenBank): Q8WZ42.4
Assay category: BCell
Result: Positive

Epitope: TITIN
Chemical type: Peptide from protein
Sequence: VKVTAENPEGVIEHKVK
Position: 1910-1926
Source molecule (GenBank): Q8WZ42.4
Assay category: BCell
Result: Positive

Epitope: TITIN
Chemical type: Peptide from protein
Sequence: VKVTAENPEGVIEHKVK
Position: 1910-1926
Source molecule (GenBank): Q8WZ42.4
Assay category: BCell
Result: Positive

Epitope: TITIN
Chemical type: Peptide from protein
Sequence: VKVTAENPEGVIEHKVK
Position: 1910-1926
Source molecule (GenBank): Q8WZ42.4
Assay category: BCell
Result: Positive-Low

Epitope: TITIN
Chemical type: Peptide from protein
Sequence: VKVTAENPEGVIEHKVK
Position: 1910-1926
Source molecule (GenBank): Q8WZ42.4
Assay category: BCell
Result: Positive

Epitope: TITIN
Chemical type: Peptide from protein
Sequence: VKVTAENPEGVIEHKVK
Position: 1910-1926
Source molecule (GenBank): Q8WZ42.4
Assay category: BCell
Result: Positive

Epitope: TITIN
Chemical type: Peptide from protein
Sequence: VKVTAENPEGVIEHKVK
Position: 1910-1926
Source molecule (GenBank): Q8WZ42.4
Assay category: BCell
Result: Positive

Epitope: TITIN
Chemical type: Peptide from protein
Sequence: VKVTAENPEGVIEHKVK
Position: 1910-1926
Source molecule (GenBank): Q8WZ42.4
Assay category: BCell
Result: Positive