Reference: Huy Quang Quach; Inna G Ovsyannikova; Gregory A Poland; Richard B Kennedy. "Evaluating immunogenicity of pathogen-derived T-cell epitopes to design a peptide-based smallpox vaccine." Scientific reports (2022).

Epitope: VAVC peptide 16
Chemical type: Peptide from protein
Sequence: VLSLELPEV
Position: 70-78
Source molecule (GenBank): AAA48114.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 16
Chemical type: Peptide from protein
Sequence: VLSLELPEV
Position: 70-78
Source molecule (GenBank): AAA48114.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 16
Chemical type: Peptide from protein
Sequence: VLSLELPEV
Position: 70-78
Source molecule (GenBank): AAA48114.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 19
Chemical type: Peptide from protein
Sequence: KIDYYIPYV
Position: 249-257
Source molecule (GenBank): 137619
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 19
Chemical type: Peptide from protein
Sequence: KIDYYIPYV
Position: 249-257
Source molecule (GenBank): 137619
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 19
Chemical type: Peptide from protein
Sequence: KIDYYIPYV
Position: 249-257
Source molecule (GenBank): 137619
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 22
Chemical type: Peptide from protein
Sequence: SLSNLDFRL
Position: 346-354
Source molecule (GenBank): P21052.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 22
Chemical type: Peptide from protein
Sequence: SLSNLDFRL
Position: 346-354
Source molecule (GenBank): P21052.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 22
Chemical type: Peptide from protein
Sequence: SLSNLDFRL
Position: 346-354
Source molecule (GenBank): P21052.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 25
Chemical type: Peptide from protein
Sequence: ILMDNKGLGV
Position: 136-145
Source molecule (GenBank): P68450.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 25
Chemical type: Peptide from protein
Sequence: ILMDNKGLGV
Position: 136-145
Source molecule (GenBank): P68450.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 25
Chemical type: Peptide from protein
Sequence: ILMDNKGLGV
Position: 136-145
Source molecule (GenBank): P68450.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 28
Chemical type: Peptide from protein
Sequence: ILDDNLYKV
Position: 18-26
Source molecule (GenBank): P21026.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 28
Chemical type: Peptide from protein
Sequence: ILDDNLYKV
Position: 18-26
Source molecule (GenBank): P21026.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 28
Chemical type: Peptide from protein
Sequence: ILDDNLYKV
Position: 18-26
Source molecule (GenBank): P21026.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 33
Chemical type: Peptide from protein
Sequence: GLLDRLYDL
Position: 482-490
Source molecule (GenBank): P21093.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 33
Chemical type: Peptide from protein
Sequence: GLLDRLYDL
Position: 482-490
Source molecule (GenBank): P21093.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 33
Chemical type: Peptide from protein
Sequence: GLLDRLYDL
Position: 482-490
Source molecule (GenBank): P21093.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 1
Chemical type: Peptide from protein
Sequence: ILIRGIINV
Position: 37-45
Source molecule (GenBank): P68630.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 7
Chemical type: Peptide from protein
Sequence: LLISADDVQEIRV
Position: 20-32
Source molecule (GenBank): P21097.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: VAVC peptide 31
Chemical type: Peptide from protein
Sequence: SLLFIPDIKL
Position: 191-200
Source molecule (GenBank): P20632.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo