Reference: Concepción Marañón; Adriana Egui; Bartolomé Carrilero; M Carmen Thomas; M Jesús Pinazo; Joaquim Gascón; Manuel Segovia; Manuel Carlos López. "Identification of HLA-A∗02:01-restricted CTL epitopes in Trypanosoma cruzi heat shock protein-70 recognized by Chagas disease patients." Microbes and infection / Institut Pasteur (2011).

Epitope: 12759
Chemical type: Peptide from protein
Sequence: YVAFTDTERL
Position: 41-50
Source molecule (GenBank): CAA47952.1
Assay category: MhcBinding
Result: Positive

Epitope: 12760
Chemical type: Peptide from protein
Sequence: QVAMNPTNTV
Position: 58-67
Source molecule (GenBank): ACI02309.1
Assay category: MhcBinding
Result: Positive

Epitope: 12761
Chemical type: Peptide from protein
Sequence: LIGRKFSDPV
Position: 73-82
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 12761
Chemical type: Peptide from protein
Sequence: LIGRKFSDPV
Position: 73-82
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 12761
Chemical type: Peptide from protein
Sequence: LIGRKFSDPV
Position: 73-82
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive

Epitope: 12762
Chemical type: Peptide from protein
Sequence: DMKHWPFKVI
Position: 86-95
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive-High

Epitope: 12763
Chemical type: Peptide from protein
Sequence: VITKGDDKPV
Position: 94-103
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive

Epitope: 12764
Chemical type: Peptide from protein
Sequence: SMVLSKMKEI
Position: 122-131
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 12764
Chemical type: Peptide from protein
Sequence: SMVLSKMKEI
Position: 122-131
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 12764
Chemical type: Peptide from protein
Sequence: SMVLSKMKEI
Position: 122-131
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive-High

Epitope: 12765
Chemical type: Peptide from protein
Sequence: KMKEIAESYL
Position: 127-136
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 12765
Chemical type: Peptide from protein
Sequence: KMKEIAESYL
Position: 127-136
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 12765
Chemical type: Peptide from protein
Sequence: KMKEIAESYL
Position: 127-136
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive-High

Epitope: 12769
Chemical type: Peptide from protein
Sequence: AIAYGLDKV
Position: 181-189
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 12769
Chemical type: Peptide from protein
Sequence: AIAYGLDKV
Position: 181-189
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 12769
Chemical type: Peptide from protein
Sequence: AIAYGLDKV
Position: 181-189
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive-High

Epitope: 12771
Chemical type: Peptide from protein
Sequence: DLGGGTFDV
Position: 201-209
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive

Epitope: 12773
Chemical type: Peptide from protein
Sequence: DSLTNLRAL
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 12773
Chemical type: Peptide from protein
Sequence: DSLTNLRAL
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 12773
Chemical type: Peptide from protein
Sequence: DSLTNLRAL
Assay category: MhcBinding
Result: Positive-High

Epitope: 12774
Chemical type: Peptide from protein
Sequence: TSSAAQATI
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 12774
Chemical type: Peptide from protein
Sequence: TSSAAQATI
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 12774
Chemical type: Peptide from protein
Sequence: TSSAAQATI
Assay category: MhcBinding
Result: Positive-High

Epitope: 12776
Chemical type: Peptide from protein
Sequence: TLQPVERVL
Position: 316-324
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 12776
Chemical type: Peptide from protein
Sequence: TLQPVERVL
Position: 316-324
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 12776
Chemical type: Peptide from protein
Sequence: TLQPVERVL
Position: 316-324
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 12776
Chemical type: Peptide from protein
Sequence: TLQPVERVL
Position: 316-324
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 12776
Chemical type: Peptide from protein
Sequence: TLQPVERVL
Position: 316-324
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 12776
Chemical type: Peptide from protein
Sequence: TLQPVERVL
Position: 316-324
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive-High

Epitope: 12777
Chemical type: Peptide from protein
Sequence: KMDKRAVHDV
Position: 328-337
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 12777
Chemical type: Peptide from protein
Sequence: KMDKRAVHDV
Position: 328-337
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 12777
Chemical type: Peptide from protein
Sequence: KMDKRAVHDV
Position: 328-337
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive-High

Epitope: 12778
Chemical type: Peptide from protein
Sequence: VVLVGGSTRI
Position: 337-346
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive

Epitope: 12780
Chemical type: Peptide from protein
Sequence: LLLDVTPLTL
Position: 395-404
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 12780
Chemical type: Peptide from protein
Sequence: LLLDVTPLTL
Position: 395-404
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 12780
Chemical type: Peptide from protein
Sequence: LLLDVTPLTL
Position: 395-404
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive-High

Epitope: 12782
Chemical type: Peptide from protein
Sequence: LLGTFELSGI
Position: 458-467
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 12782
Chemical type: Peptide from protein
Sequence: LLGTFELSGI
Position: 458-467
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 12782
Chemical type: Peptide from protein
Sequence: LLGTFELSGI
Position: 458-467
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive-High

Epitope: 12783
Chemical type: Peptide from protein
Sequence: GIPPPPRGV
Position: 466-474
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 12783
Chemical type: Peptide from protein
Sequence: GIPPPPRGV
Position: 466-474
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 12783
Chemical type: Peptide from protein
Sequence: GIPPPPRGV
Position: 466-474
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive-High

Epitope: 12785
Chemical type: Peptide from protein
Sequence: IVLTNDKGRL
Position: 504-513
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive

Epitope: 12786
Chemical type: Peptide from protein
Sequence: KIEEADKKTI
Position: 564-573
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 12786
Chemical type: Peptide from protein
Sequence: KIEEADKKTI
Position: 564-573
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 12786
Chemical type: Peptide from protein
Sequence: KIEEADKKTI
Position: 564-573
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive-High

Epitope: 12787
Chemical type: Peptide from protein
Sequence: TITSAVEEAL
Position: 572-581
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive

Epitope: 12788
Chemical type: Peptide from protein
Sequence: KMYGGMAGA
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 12788
Chemical type: Peptide from protein
Sequence: KMYGGMAGA
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 12788
Chemical type: Peptide from protein
Sequence: KMYGGMAGA
Assay category: MhcBinding
Result: Positive-High

Epitope: 12789
Chemical type: Peptide from protein
Sequence: GMPGGMPGGM
Position: 621-630
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 12789
Chemical type: Peptide from protein
Sequence: GMPGGMPGGM
Position: 621-630
Source molecule (GenBank): CAA30115.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 12789
Chemical type: Peptide from protein
Sequence: GMPGGMPGGM
Position: 621-630
Source molecule (GenBank): CAA30115.1
Assay category: MhcBinding
Result: Positive-High

Epitope: Flu-MA
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): AAC80155.1
Assay category: MhcBinding
Result: Positive