Reference: Sabine Tischer; René Geyeregger; Julian Kwoczek; Albert Heim; Constanca Figueiredo; Rainer Blasczyk; Britta Maecker-Kolhoff; Britta Eiz-Vesper. "Discovery of immunodominant T-cell epitopes reveals penton protein as a second immunodominant target in human adenovirus infection." Journal of translational medicine (2016).

Epitope: A01 Hexon TDLG
Chemical type: Peptide from protein
Sequence: TDLGQNLLY
Position: 886-894
Source molecule (GenBank): P04133.3
Assay category: TCell
Result: Positive-High
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A01 Hexon TDLG
Chemical type: Peptide from protein
Sequence: TDLGQNLLY
Position: 886-894
Source molecule (GenBank): P04133.3
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A01 Hexon TDLG
Chemical type: Peptide from protein
Sequence: TDLGQNLLY
Position: 886-894
Source molecule (GenBank): P04133.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A01 Hexon TDLG
Chemical type: Peptide from protein
Sequence: TDLGQNLLY
Position: 886-894
Source molecule (GenBank): P04133.3
Assay category: TCell
Result: Positive
Host:  child
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A01 Hexon TDLG
Chemical type: Peptide from protein
Sequence: TDLGQNLLY
Position: 886-894
Source molecule (GenBank): P04133.3
Assay category: MhcBinding
Result: Positive-High

Epitope: A01 Hexon TNDQ
Chemical type: Peptide from protein
Sequence: TNDQSFNDY
Position: 638-646
Source molecule (GenBank): P04133.3
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A01 Hexon TNDQ
Chemical type: Peptide from protein
Sequence: TNDQSFNDY
Position: 638-646
Source molecule (GenBank): P04133.3
Assay category: MhcBinding
Result: Positive

Epitope: A01 Hexon QNDP
Chemical type: Peptide from protein
Sequence: QNDPTVVMY
Position: 250-258
Source molecule (GenBank): AAZ99995.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A01 Hexon QNDP
Chemical type: Peptide from protein
Sequence: QNDPTVVMY
Position: 250-258
Source molecule (GenBank): AAZ99995.1
Assay category: MhcBinding
Result: Positive

Epitope: A02 Hexon TLLY
Chemical type: Peptide from protein
Sequence: TLLYVLFEV
Position: 914-922
Source molecule (GenBank): P04133.3
Assay category: TCell
Result: Positive-High
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A02 Hexon TLLY
Chemical type: Peptide from protein
Sequence: TLLYVLFEV
Position: 914-922
Source molecule (GenBank): P04133.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A02 Hexon TLLY
Chemical type: Peptide from protein
Sequence: TLLYVLFEV
Position: 914-922
Source molecule (GenBank): P04133.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A02 Hexon TLLY
Chemical type: Peptide from protein
Sequence: TLLYVLFEV
Position: 914-922
Source molecule (GenBank): P04133.3
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A02 Hexon TLLY
Chemical type: Peptide from protein
Sequence: TLLYVLFEV
Position: 914-922
Source molecule (GenBank): P04133.3
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A02 Hexon TLLY
Chemical type: Peptide from protein
Sequence: TLLYVLFEV
Position: 914-922
Source molecule (GenBank): P04133.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A02 Hexon TLLY
Chemical type: Peptide from protein
Sequence: TLLYVLFEV
Position: 914-922
Source molecule (GenBank): P04133.3
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A02 Hexon TLLY
Chemical type: Peptide from protein
Sequence: TLLYVLFEV
Position: 914-922
Source molecule (GenBank): P04133.3
Assay category: MhcBinding
Result: Positive

Epitope: A02 Hexon TLAV
Chemical type: Peptide from protein
Sequence: TLAVGDNRV
Position: 85-93
Source molecule (GenBank): P04133.3
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A02 Hexon TLAV
Chemical type: Peptide from protein
Sequence: TLAVGDNRV
Position: 85-93
Source molecule (GenBank): P04133.3
Assay category: MhcBinding
Result: Positive

Epitope: B08 Hexon GLRY
Chemical type: Peptide from protein
Sequence: GLRYRSMLL
Position: 542-550
Source molecule (GenBank): P04133.3
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A01 Penton STDV
Chemical type: Peptide from protein
Sequence: STDVASLNY
Position: 76-84
Source molecule (GenBank): AAW65509.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A01 Penton STDV
Chemical type: Peptide from protein
Sequence: STDVASLNY
Position: 76-84
Source molecule (GenBank): AAW65509.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A01 Penton STDV
Chemical type: Peptide from protein
Sequence: STDVASLNY
Position: 76-84
Source molecule (GenBank): AAW65509.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A01 Penton STDV
Chemical type: Peptide from protein
Sequence: STDVASLNY
Position: 76-84
Source molecule (GenBank): AAW65509.1
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A01 Penton STDV
Chemical type: Peptide from protein
Sequence: STDVASLNY
Position: 76-84
Source molecule (GenBank): AAW65509.1
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A01 Penton STDV
Chemical type: Peptide from protein
Sequence: STDVASLNY
Position: 76-84
Source molecule (GenBank): AAW65509.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A01 Penton STDV
Chemical type: Peptide from protein
Sequence: STDVASLNY
Position: 76-84
Source molecule (GenBank): AAW65509.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A01 Penton STDV
Chemical type: Peptide from protein
Sequence: STDVASLNY
Position: 76-84
Source molecule (GenBank): AAW65509.1
Assay category: MhcBinding
Result: Positive-High

Epitope: A01 Penton SNDS
Chemical type: Peptide from protein
Sequence: SNDSTFTQY
Position: 395-403
Source molecule (GenBank): AAW65509.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A01 Penton SNDS
Chemical type: Peptide from protein
Sequence: SNDSTFTQY
Position: 395-403
Source molecule (GenBank): AAW65509.1
Assay category: MhcBinding
Result: Positive

Epitope: A01 Penton SSDI
Chemical type: Peptide from protein
Sequence: SSDIASLNY
Position: 72-80
Source molecule (GenBank): CAO78633.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A01 Penton SSDI
Chemical type: Peptide from protein
Sequence: SSDIASLNY
Position: 72-80
Source molecule (GenBank): CAO78633.1
Assay category: MhcBinding
Result: Positive-High

Epitope: A01 Penton LTDH
Chemical type: Peptide from protein
Sequence: LTDHGTLPL
Position: 523-531
Source molecule (GenBank): AAW65509.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A01 Penton LTDH
Chemical type: Peptide from protein
Sequence: LTDHGTLPL
Position: 523-531
Source molecule (GenBank): AAW65509.1
Assay category: MhcBinding
Result: Positive

Epitope: A02 Penton ILHT
Chemical type: Peptide from protein
Sequence: ILHTNMPNV
Position: 122-130
Source molecule (GenBank): CAO78633.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A02 Penton ILHT
Chemical type: Peptide from protein
Sequence: ILHTNMPNV
Position: 122-130
Source molecule (GenBank): CAO78633.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A02 Penton ILHT
Chemical type: Peptide from protein
Sequence: ILHTNMPNV
Position: 122-130
Source molecule (GenBank): CAO78633.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A02 Penton ILHT
Chemical type: Peptide from protein
Sequence: ILHTNMPNV
Position: 122-130
Source molecule (GenBank): CAO78633.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A02 Penton ILHT
Chemical type: Peptide from protein
Sequence: ILHTNMPNV
Position: 122-130
Source molecule (GenBank): CAO78633.1
Assay category: MhcBinding
Result: Positive-High

Epitope: A02 Penton GNIP
Chemical type: Peptide from protein
Sequence: GNIPALLDV
Position: 279-287
Source molecule (GenBank): CAO78633.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A02 Penton GNIP
Chemical type: Peptide from protein
Sequence: GNIPALLDV
Position: 279-287
Source molecule (GenBank): CAO78633.1
Assay category: MhcBinding
Result: Positive

Epitope: A03 Penton LLPG
Chemical type: Peptide from protein
Sequence: LLPGCGVDF
Position: 240-248
Source molecule (GenBank): CAO78633.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B08 Penton NTKY
Chemical type: Peptide from protein
Sequence: NTKYRSWYL
Position: 334-342
Source molecule (GenBank): CAO78633.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B08 Penton DSKG
Chemical type: Peptide from protein
Sequence: DSKGRSYNL
Position: 320-328
Source molecule (GenBank): CAO78633.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B08 Penton DSKG
Chemical type: Peptide from protein
Sequence: DSKGRSYNL
Position: 320-328
Source molecule (GenBank): CAO78633.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B08 Penton DSKG
Chemical type: Peptide from protein
Sequence: DSKGRSYNL
Position: 320-328
Source molecule (GenBank): CAO78633.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B08 Penton DSKG
Chemical type: Peptide from protein
Sequence: DSKGRSYNL
Position: 320-328
Source molecule (GenBank): CAO78633.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B08 Penton LTKD
Chemical type: Peptide from protein
Sequence: LTKDKQVEL
Position: 153-161
Source molecule (GenBank): CAC67479.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B08 Penton DSKK
Chemical type: Peptide from protein
Sequence: DSKKRSYNL
Position: 385-393
Source molecule (GenBank): AAW65509.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B08 Penton DSKK
Chemical type: Peptide from protein
Sequence: DSKKRSYNL
Position: 385-393
Source molecule (GenBank): AAW65509.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B08 Penton DSKK
Chemical type: Peptide from protein
Sequence: DSKKRSYNL
Position: 385-393
Source molecule (GenBank): AAW65509.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B08 Penton DSKK
Chemical type: Peptide from protein
Sequence: DSKKRSYNL
Position: 385-393
Source molecule (GenBank): AAW65509.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A01 pp65 YSEH
Chemical type: Peptide from protein
Sequence: YSEHPTFTSQY
Position: 353-363
Source molecule (GenBank): AAA45994.1
Assay category: MhcBinding
Result: Positive-High

Epitope: A02 pp65 NLVP
Chemical type: Peptide from protein
Sequence: NLVPMVATV
Position: 485-493
Source molecule (GenBank): AAA45994.1
Assay category: MhcBinding
Result: Positive-High