Reference: Niharika Shukla; Wai Kwan Tang; Camila H Coelho; Carole A Long; Sara A Healy; Issaka Sagara; Kazutoyo Miura; Patrick E Duffy; Niraj H Tolia. "A human antibody epitope map of the malaria vaccine antigen Pfs25." NPJ vaccines (2023).

Epitope: Epitope of AS01-04 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: V29, C30, K31, R32, G33, E47, N48, D49, L50, E59, E60, K61, V62, L63, K64, D66, K68, T69, K72, K163, E188, S189, S190, I191
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Quantitative measurement: 251000.0
Host:  18-50 years

Epitope: Epitope of AS01-04 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: V29, C30, K31, R32, G33, E47, N48, D49, L50, E59, E60, K61, V62, L63, K64, D66, K68, T69, K72, K163, E188, S189, S190, I191
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000090
Host:  18-50 years

Epitope: Epitope of AS01-04 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: V29, C30, K31, R32, G33, E47, N48, D49, L50, E59, E60, K61, V62, L63, K64, D66, K68, T69, K72, K163, E188, S189, S190, I191
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Host:  18-50 years

Epitope: Epitope of AS01-04 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: V29, C30, K31, R32, G33, E47, N48, D49, L50, E59, E60, K61, V62, L63, K64, D66, K68, T69, K72, K163, E188, S189, S190, I191
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Host:  18-50 years

Epitope: Epitope of AS01-04 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: V29, C30, K31, R32, G33, E47, N48, D49, L50, E59, E60, K61, V62, L63, K64, D66, K68, T69, K72, K163, E188, S189, S190, I191
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.3
Host:  18-50 years

Epitope: Epitope of AS01-04 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: V29, C30, K31, R32, G33, E47, N48, D49, L50, E59, E60, K61, V62, L63, K64, D66, K68, T69, K72, K163, E188, S189, S190, I191
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.37
Host:  18-50 years

Epitope: Epitope of AS01-50 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: V70, N71, K79, I81, K82, I83, D84, G85, N86, P87, V88, S89, K93, C94, N95, L96, D99, N108, K111
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Quantitative measurement: 68.6
Host:  18-50 years

Epitope: Epitope of AS01-50 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: V70, N71, K79, I81, K82, I83, D84, G85, N86, P87, V88, S89, K93, C94, N95, L96, D99, N108, K111
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.02049
Host:  18-50 years

Epitope: Epitope of AS01-50 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: V70, N71, K79, I81, K82, I83, D84, G85, N86, P87, V88, S89, K93, C94, N95, L96, D99, N108, K111
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Host:  18-50 years

Epitope: Epitope of AS01-50 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: V70, N71, K79, I81, K82, I83, D84, G85, N86, P87, V88, S89, K93, C94, N95, L96, D99, N108, K111
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Quantitative measurement: 284000.0
Host:  18-50 years

Epitope: Epitope of AS01-50 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: V70, N71, K79, I81, K82, I83, D84, G85, N86, P87, V88, S89, K93, C94, N95, L96, D99, N108, K111
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.3
Host:  18-50 years

Epitope: Epitope of AS01-50 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: V70, N71, K79, I81, K82, I83, D84, G85, N86, P87, V88, S89, K93, C94, N95, L96, D99, N108, K111
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Host:  18-50 years

Epitope: Epitope of AS01-63 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: I81, K82, I83, D84, G85, N86, P87, S89, A91, C92, K93, C94, Y98, D99, N108, K111
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Quantitative measurement: 8.71
Host:  18-50 years

Epitope: Epitope of AS01-63 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: I81, K82, I83, D84, G85, N86, P87, S89, A91, C92, K93, C94, Y98, D99, N108, K111
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.1
Host:  18-50 years

Epitope: Epitope of AS01-63 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: I81, K82, I83, D84, G85, N86, P87, S89, A91, C92, K93, C94, Y98, D99, N108, K111
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Host:  18-50 years

Epitope: Epitope of AS01-63 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: I81, K82, I83, D84, G85, N86, P87, S89, A91, C92, K93, C94, Y98, D99, N108, K111
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Quantitative measurement: 228000.0
Host:  18-50 years

Epitope: Epitope of AS01-63 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: I81, K82, I83, D84, G85, N86, P87, S89, A91, C92, K93, C94, Y98, D99, N108, K111
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00192
Host:  18-50 years

Epitope: Epitope of AS01-63 scFv on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: I81, K82, I83, D84, G85, N86, P87, S89, A91, C92, K93, C94, Y98, D99, N108, K111
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Host:  18-50 years

Epitope: Epitope of 1245 Fab on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: F34, I36, M38, E43, K45, C46, E47, N48, D49, K61, N102, N103, V104, G116, N117, G118, K119, N136, I137, K169, A170, V171, D172, G173, I174, K176, D178
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Host:  18-50 years

Epitope: Epitope of 2530 Fab on Pfs25
Chemical type: Discontinuous protein residues
Discontinuous residues: N48, D49, L50, E60, K61, V62, L63, K64, E67, K68, K72
Source molecule (GenBank): P13829.1
Assay category: BCell
Result: Positive
Host:  18-50 years