Reference: Melanie D Leech; Antonio Carrillo-Vico; Roland S Liblau; Stephen M Anderton. "Recognition of a high affinity MHC class I-restricted epitope of myelin oligodendrocyte glycoprotein by CD8⁺ T cells derived from autoantigen-deficient mice." Frontiers in immunology (2011).

Epitope: MOG 6-20
Chemical type: Peptide from protein
Sequence: IGPGYPIRALVGDEA
Position: 34-48
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 6-20
Chemical type: Peptide from protein
Sequence: IGPGYPIRALVGDEA
Position: 34-48
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 11-25
Chemical type: Peptide from protein
Sequence: PIRALVGDEAELPCR
Position: 39-53
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 11-25
Chemical type: Peptide from protein
Sequence: PIRALVGDEAELPCR
Position: 39-53
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 16-30
Chemical type: Peptide from protein
Sequence: VGDEAELPCRISPGK
Position: 44-58
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 16-30
Chemical type: Peptide from protein
Sequence: VGDEAELPCRISPGK
Position: 44-58
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 21-35
Chemical type: Peptide from protein
Sequence: ELPCRISPGKNATGM
Position: 49-63
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 21-35
Chemical type: Peptide from protein
Sequence: ELPCRISPGKNATGM
Position: 49-63
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 26-40
Chemical type: Peptide from protein
Sequence: ISPGKNATGMEVGWY
Position: 54-68
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 26-40
Chemical type: Peptide from protein
Sequence: ISPGKNATGMEVGWY
Position: 54-68
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 31-45
Chemical type: Peptide from protein
Sequence: NATGMEVGWYRSPFS
Position: 59-73
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 31-45
Chemical type: Peptide from protein
Sequence: NATGMEVGWYRSPFS
Position: 59-73
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 41-55
Chemical type: Peptide from protein
Sequence: RSPFSRVVHLYRNGK
Position: 69-83
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 41-55
Chemical type: Peptide from protein
Sequence: RSPFSRVVHLYRNGK
Position: 69-83
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 46-60
Chemical type: Peptide from protein
Sequence: RVVHLYRNGKDQDAE
Position: 74-88
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 46-60
Chemical type: Peptide from protein
Sequence: RVVHLYRNGKDQDAE
Position: 74-88
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 51-65
Chemical type: Peptide from protein
Sequence: YRNGKDQDAEQAPEY
Position: 79-93
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 51-65
Chemical type: Peptide from protein
Sequence: YRNGKDQDAEQAPEY
Position: 79-93
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 56-70
Chemical type: Peptide from protein
Sequence: DQDAEQAPEYRGRTE
Position: 84-98
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 56-70
Chemical type: Peptide from protein
Sequence: DQDAEQAPEYRGRTE
Position: 84-98
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 61-75
Chemical type: Peptide from protein
Sequence: QAPEYRGRTELLKET
Position: 89-103
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 61-75
Chemical type: Peptide from protein
Sequence: QAPEYRGRTELLKET
Position: 89-103
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 66-80
Chemical type: Peptide from protein
Sequence: RGRTELLKETISEGK
Position: 94-108
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 66-80
Chemical type: Peptide from protein
Sequence: RGRTELLKETISEGK
Position: 94-108
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 71-85
Chemical type: Peptide from protein
Sequence: LLKETISEGKVTLRI
Position: 99-113
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 71-85
Chemical type: Peptide from protein
Sequence: LLKETISEGKVTLRI
Position: 99-113
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 76-90
Chemical type: Peptide from protein
Sequence: ISEGKVTLRIQNVRF
Position: 104-118
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 76-90
Chemical type: Peptide from protein
Sequence: ISEGKVTLRIQNVRF
Position: 104-118
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 86-101
Chemical type: Peptide from protein
Sequence: QNVRFSDEGGYTCFFR
Position: 114-129
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 86-101
Chemical type: Peptide from protein
Sequence: QNVRFSDEGGYTCFFR
Position: 114-129
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 91-105
Chemical type: Peptide from protein
Sequence: SDEGGYTCFFRDHSY
Position: 119-133
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 91-105
Chemical type: Peptide from protein
Sequence: SDEGGYTCFFRDHSY
Position: 119-133
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 96-111
Chemical type: Peptide from protein
Sequence: YTCFFRDHSYQEEAAM
Position: 124-139
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 96-111
Chemical type: Peptide from protein
Sequence: YTCFFRDHSYQEEAAM
Position: 124-139
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 101-115
Chemical type: Peptide from protein
Sequence: RDHSYQEEAAMELKV
Position: 129-143
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 101-115
Chemical type: Peptide from protein
Sequence: RDHSYQEEAAMELKV
Position: 129-143
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 106-120
Chemical type: Peptide from protein
Sequence: QEEAAMELKVEDPFY
Position: 134-148
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 106-120
Chemical type: Peptide from protein
Sequence: QEEAAMELKVEDPFY
Position: 134-148
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 63-83
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive
Host:  6-12 weeks

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 63-83
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive
Host:  6-12 weeks
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 63-83
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Negative
Host:  6-12 weeks

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 63-83
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive
Host:  6-12 weeks
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 63-83
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive
Host:  6-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 63-83
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive
Host:  6-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 63-83
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive
Host:  6-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: MOG 35-55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 63-83
Source molecule (GenBank): Q61885.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: MOG 37-46
Chemical type: Peptide from protein
Sequence: VGWYRSPFSR
Position: 65-74
Source molecule (GenBank): Q61885.1
Assay category: MhcBinding
Result: Negative

Epitope: MOG 42-50
Chemical type: Peptide from protein
Sequence: SPFSRVVHL
Position: 70-78
Source molecule (GenBank): Q61885.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: MOG 42-50
Chemical type: Peptide from protein
Sequence: SPFSRVVHL
Position: 70-78
Source molecule (GenBank): Q61885.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: MOG 41-50
Chemical type: Peptide from protein
Sequence: RSPFSRVVHL
Position: 69-78
Source molecule (GenBank): Q61885.1
Assay category: MhcBinding
Result: Positive-High