Reference: Monica Schaller; Monique Vogel; Karim Kentouche; Bernhard Lämmle; Johanna A Kremer Hovinga. "The splenic autoimmune response to ADAMTS13 in thrombotic thrombocytopenic purpura contains recurrent antigen-binding CDR3 motifs." Blood (2014).

Epitope: Group 2
Chemical type: Discontinuous protein residues
Discontinuous residues: A234, G235,  R236, A237, R238, E239, Y240, V241, T242, F243, L244, A266, V267, R268, I269, G270, G271, R272, Y273, V274, V275, I325, Q326, V327, Y328, R329, R330, Y331, G332, E333, E334, Y335
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 28.0

Epitope: Group 2
Chemical type: Discontinuous protein residues
Discontinuous residues: A234, G235,  R236, A237, R238, E239, Y240, V241, T242, F243, L244, A266, V267, R268, I269, G270, G271, R272, Y273, V274, V275, I325, Q326, V327, Y328, R329, R330, Y331, G332, E333, E334, Y335
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive

Epitope: Group 2
Chemical type: Discontinuous protein residues
Discontinuous residues: A234, G235,  R236, A237, R238, E239, Y240, V241, T242, F243, L244, A266, V267, R268, I269, G270, G271, R272, Y273, V274, V275, I325, Q326, V327, Y328, R329, R330, Y331, G332, E333, E334, Y335
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.43

Epitope: Group 2
Chemical type: Discontinuous protein residues
Discontinuous residues: A234, G235,  R236, A237, R238, E239, Y240, V241, T242, F243, L244, A266, V267, R268, I269, G270, G271, R272, Y273, V274, V275, I325, Q326, V327, Y328, R329, R330, Y331, G332, E333, E334, Y335
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 96.0

Epitope: Group 2
Chemical type: Discontinuous protein residues
Discontinuous residues: A234, G235,  R236, A237, R238, E239, Y240, V241, T242, F243, L244, A266, V267, R268, I269, G270, G271, R272, Y273, V274, V275, I325, Q326, V327, Y328, R329, R330, Y331, G332, E333, E334, Y335
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 9.0

Epitope: Group 2
Chemical type: Discontinuous protein residues
Discontinuous residues: A234, G235,  R236, A237, R238, E239, Y240, V241, T242, F243, L244, A266, V267, R268, I269, G270, G271, R272, Y273, V274, V275, I325, Q326, V327, Y328, R329, R330, Y331, G332, E333, E334, Y335
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 9.2

Epitope: Group 2
Chemical type: Discontinuous protein residues
Discontinuous residues: A234, G235,  R236, A237, R238, E239, Y240, V241, T242, F243, L244, A266, V267, R268, I269, G270, G271, R272, Y273, V274, V275, I325, Q326, V327, Y328, R329, R330, Y331, G332, E333, E334, Y335
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 58.0

Epitope: Group 2
Chemical type: Discontinuous protein residues
Discontinuous residues: A234, G235,  R236, A237, R238, E239, Y240, V241, T242, F243, L244, A266, V267, R268, I269, G270, G271, R272, Y273, V274, V275, I325, Q326, V327, Y328, R329, R330, Y331, G332, E333, E334, Y335
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive

Epitope: Group 2
Chemical type: Discontinuous protein residues
Discontinuous residues: A234, G235,  R236, A237, R238, E239, Y240, V241, T242, F243, L244, A266, V267, R268, I269, G270, G271, R272, Y273, V274, V275, I325, Q326, V327, Y328, R329, R330, Y331, G332, E333, E334, Y335
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 9.2

Epitope: Group 2
Chemical type: Discontinuous protein residues
Discontinuous residues: A234, G235,  R236, A237, R238, E239, Y240, V241, T242, F243, L244, A266, V267, R268, I269, G270, G271, R272, Y273, V274, V275, I325, Q326, V327, Y328, R329, R330, Y331, G332, E333, E334, Y335
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive

Epitope: Group 3 (661-671)
Chemical type: Peptide from protein
Sequence: YGEEYGNLTRP
Position: 331-341
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive

Epitope: Group 3 (661-671)
Chemical type: Peptide from protein
Sequence: YGEEYGNLTRP
Position: 331-341
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 28.0

Epitope: Group 3 (661-671)
Chemical type: Peptide from protein
Sequence: YGEEYGNLTRP
Position: 331-341
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 79.0

Epitope: Group 3 (661-671)
Chemical type: Peptide from protein
Sequence: YGEEYGNLTRP
Position: 331-341
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive

Epitope: Group 3 (661-671)
Chemical type: Peptide from protein
Sequence: YGEEYGNLTRP
Position: 331-341
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive

Epitope: Fab 1h epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: F232, T233, A234, G235, R236, A237, R238, E239, Y240, N257, H258, R259, P260, L261, F262, T263, H264, L265
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive

Epitope: Fab 1h epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: F232, T233, A234, G235, R236, A237, R238, E239, Y240, N257, H258, R259, P260, L261, F262, T263, H264, L265
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive

Epitope: Fab 1h epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: F232, T233, A234, G235, R236, A237, R238, E239, Y240, N257, H258, R259, P260, L261, F262, T263, H264, L265
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 7.2

Epitope: Fab 1h epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: F232, T233, A234, G235, R236, A237, R238, E239, Y240, N257, H258, R259, P260, L261, F262, T263, H264, L265
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive

Epitope: Fab 2a epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: R238, E239, Y240, V241, T242, F243, L244, T245, V246, T247, P248, I325, Q326, V327, Y328, R329, R330, Y331, G332, E333, E334, Y335
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive

Epitope: Fab 2a epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: R238, E239, Y240, V241, T242, F243, L244, T245, V246, T247, P248, I325, Q326, V327, Y328, R329, R330, Y331, G332, E333, E334, Y335
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive

Epitope: Fab 2a epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: R238, E239, Y240, V241, T242, F243, L244, T245, V246, T247, P248, I325, Q326, V327, Y328, R329, R330, Y331, G332, E333, E334, Y335
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 26.0

Epitope: Fab 2a epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: R238, E239, Y240, V241, T242, F243, L244, T245, V246, T247, P248, I325, Q326, V327, Y328, R329, R330, Y331, G332, E333, E334, Y335
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive

Epitope: Fab 2h epitope
Chemical type: Peptide from protein
Sequence: LTSVYIANHRPLFTHLAVRIG
Position: 250-270
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive

Epitope: Fab 2h epitope
Chemical type: Peptide from protein
Sequence: LTSVYIANHRPLFTHLAVRIG
Position: 250-270
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive
Quantitative measurement: 35.0

Epitope: Fab 2h epitope
Chemical type: Peptide from protein
Sequence: LTSVYIANHRPLFTHLAVRIG
Position: 250-270
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive

Epitope: Fab 2h epitope
Chemical type: Peptide from protein
Sequence: LTSVYIANHRPLFTHLAVRIG
Position: 250-270
Source molecule (GenBank): EAW88083.1
Assay category: BCell
Result: Positive