Reference: M Shirai; T Arichi; M Chen; T Masaki; M Nishioka; K Ikeda; H Takahashi; N Enomoto; T Saito; M E Major; T Nakazawa; T Akatsuka; S M Feinstone; J A Berzofsky. "T cell recognition of hypervariable region-1 from hepatitis C virus envelope protein with multiple class II MHC molecules in mice and humans: preferential help for induction of antibodies to the hypervariable region." Journal of immunology (Baltimore, Md. : 1950) (1999).

Epitope: HVR1 SS1
Chemical type: Peptide from protein
Sequence: THVTGGSAGHTTAGLVGLLTPGAKQNIQLINT
Position: 385-416
Source molecule (GenBank): AAB67037.1
Assay category: TCell
Result: Positive
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HVR1 SS1
Chemical type: Peptide from protein
Sequence: THVTGGSAGHTTAGLVGLLTPGAKQNIQLINT
Position: 385-416
Source molecule (GenBank): AAB67037.1
Assay category: TCell
Result: Positive
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HVR1 SS1
Chemical type: Peptide from protein
Sequence: THVTGGSAGHTTAGLVGLLTPGAKQNIQLINT
Position: 385-416
Source molecule (GenBank): AAB67037.1
Assay category: TCell
Result: Positive
MHC allele types: 327
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HVR1 SS1
Chemical type: Peptide from protein
Sequence: THVTGGSAGHTTAGLVGLLTPGAKQNIQLINT
Position: 385-416
Source molecule (GenBank): AAB67037.1
Assay category: TCell
Result: Positive
MHC allele types: 327
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HVR1 SS2
Chemical type: Peptide from protein
Sequence: THVTGGSAGHTVSGFVSLLAPGAKQNVQLINT
Position: 385-416
Source molecule (GenBank): AAA45676.1
Assay category: TCell
Result: Positive
MHC allele types: 353 336
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HVR1 SS2
Chemical type: Peptide from protein
Sequence: THVTGGSAGHTVSGFVSLLAPGAKQNVQLINT
Position: 385-416
Source molecule (GenBank): AAA45676.1
Assay category: TCell
Result: Positive
MHC allele types: 353 336
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: SS3 p390-401
Chemical type: Peptide from protein
Sequence: GRVASSTQSLVS
Position: 390-401
Source molecule (GenBank): BAA14233.1
Assay category: TCell
Result: Positive
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: SS3 p390-401
Chemical type: Peptide from protein
Sequence: GRVASSTQSLVS
Position: 390-401
Source molecule (GenBank): BAA14233.1
Assay category: TCell
Result: Negative
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SS3 p390-401
Chemical type: Peptide from protein
Sequence: GRVASSTQSLVS
Position: 390-401
Source molecule (GenBank): BAA14233.1
Assay category: TCell
Result: Positive
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SS3 p390-401
Chemical type: Peptide from protein
Sequence: GRVASSTQSLVS
Position: 390-401
Source molecule (GenBank): BAA14233.1
Assay category: TCell
Result: Positive
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HVR1 SS4
Chemical type: Peptide from protein
Sequence: THTVGGSTAHNARTLTGMFSLGARQKIQLINT
Position: 385-416
Source molecule (GenBank): P26660.3
Assay category: TCell
Result: Positive
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HVR1 SS4
Chemical type: Peptide from protein
Sequence: THTVGGSTAHNARTLTGMFSLGARQKIQLINT
Position: 385-416
Source molecule (GenBank): P26660.3
Assay category: TCell
Result: Positive
MHC allele types: 341 353
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HVR1 SS4
Chemical type: Peptide from protein
Sequence: THTVGGSTAHNARTLTGMFSLGARQKIQLINT
Position: 385-416
Source molecule (GenBank): P26660.3
Assay category: TCell
Result: Positive
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HVR1 SS4
Chemical type: Peptide from protein
Sequence: THTVGGSTAHNARTLTGMFSLGARQKIQLINT
Position: 385-416
Source molecule (GenBank): P26660.3
Assay category: TCell
Result: Positive
MHC allele types: 341 353
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: SS3 p403-411
Chemical type: Peptide from protein
Sequence: LSQGPSQKI
Position: 403-411
Source molecule (GenBank): BAA14233.1
Assay category: TCell
Result: Positive
MHC allele types: 341 353
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HVR1 SS3
Chemical type: Peptide from protein
Sequence: THVTGGRVASSTQSLVSWLSQGPSQKIQLVNT
Position: 385-416
Source molecule (GenBank): BAA14233.1
Assay category: BCell
Result: Positive
Host:  8 weeks

Epitope: HVR1 SS3
Chemical type: Peptide from protein
Sequence: THVTGGRVASSTQSLVSWLSQGPSQKIQLVNT
Position: 385-416
Source molecule (GenBank): BAA14233.1
Assay category: BCell
Result: Positive
Host:  8 weeks

Epitope: HVR1 SS3
Chemical type: Peptide from protein
Sequence: THVTGGRVASSTQSLVSWLSQGPSQKIQLVNT
Position: 385-416
Source molecule (GenBank): BAA14233.1
Assay category: TCell
Result: Positive
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HVR1 SS3
Chemical type: Peptide from protein
Sequence: THVTGGRVASSTQSLVSWLSQGPSQKIQLVNT
Position: 385-416
Source molecule (GenBank): BAA14233.1
Assay category: TCell
Result: Positive
MHC allele types: 327
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HVR1 SS3
Chemical type: Peptide from protein
Sequence: THVTGGRVASSTQSLVSWLSQGPSQKIQLVNT
Position: 385-416
Source molecule (GenBank): BAA14233.1
Assay category: TCell
Result: Positive
MHC allele types: 341 352 353
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HVR1 SS3
Chemical type: Peptide from protein
Sequence: THVTGGRVASSTQSLVSWLSQGPSQKIQLVNT
Position: 385-416
Source molecule (GenBank): BAA14233.1
Assay category: TCell
Result: Positive
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HVR1 SS3
Chemical type: Peptide from protein
Sequence: THVTGGRVASSTQSLVSWLSQGPSQKIQLVNT
Position: 385-416
Source molecule (GenBank): BAA14233.1
Assay category: TCell
Result: Positive
MHC allele types: 327
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HVR1 SS3
Chemical type: Peptide from protein
Sequence: THVTGGRVASSTQSLVSWLSQGPSQKIQLVNT
Position: 385-416
Source molecule (GenBank): BAA14233.1
Assay category: TCell
Result: Positive
MHC allele types: 341 353 352 336
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: SS1 p390-410
Chemical type: Peptide from protein
Sequence: GSAGHTTAGLVGLLTPGAKQN
Position: 390-410
Source molecule (GenBank): AAB67037.1
Assay category: BCell
Result: Positive

Epitope: SS2 p390-410
Chemical type: Peptide from protein
Sequence: GSAGHTVSGFVSLLAPGAKQN
Position: 390-410
Source molecule (GenBank): AAA45676.1
Assay category: BCell
Result: Positive

Epitope: SS3 p390-410
Chemical type: Peptide from protein
Sequence: GRVASSTQSLVSWLSQGPSQK
Position: 390-410
Source molecule (GenBank): BAA14233.1
Assay category: BCell
Result: Positive