Reference: Valentina Bianchi; Anna Bulek; Anna Fuller; Angharad Lloyd; Meriem Attaf; Pierre J Rizkallah; Garry Dolton; Andrew K Sewell; David K Cole. "A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen." The Journal of biological chemistry (2016).

Epitope: A2-YLE: gp100 (280-288)
Chemical type: Peptide from protein
Sequence: YLEPGPVTA
Position: 280-288
Source molecule (GenBank): P40967.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE: gp100 (280-288)
Chemical type: Peptide from protein
Sequence: YLEPGPVTA
Position: 280-288
Source molecule (GenBank): P40967.2
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE: gp100 (280-288)
Chemical type: Peptide from protein
Sequence: YLEPGPVTA
Position: 280-288
Source molecule (GenBank): P40967.2
Assay category: TCell
Result: Positive
Quantitative measurement: 7600.0

Epitope: A2-YLE: gp100 (280-288)
Chemical type: Peptide from protein
Sequence: YLEPGPVTA
Position: 280-288
Source molecule (GenBank): P40967.2
Assay category: TCell
Result: Positive
Quantitative measurement: 26500.0

Epitope: A2-YLE: gp100 (280-288)
Chemical type: Peptide from protein
Sequence: YLEPGPVTA
Position: 280-288
Source molecule (GenBank): P40967.2
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE: gp100 (280-288)
Chemical type: Peptide from protein
Sequence: YLEPGPVTA
Position: 280-288
Source molecule (GenBank): P40967.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.97

Epitope: A2-YLE-9V
Chemical type: Peptide, no natural source
Sequence: YLEPGPVTV
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-9V
Chemical type: Peptide, no natural source
Sequence: YLEPGPVTV
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-9V
Chemical type: Peptide, no natural source
Sequence: YLEPGPVTV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-9V
Chemical type: Peptide, no natural source
Sequence: YLEPGPVTV
Assay category: TCell
Result: Positive
Quantitative measurement: 6300.0

Epitope: A2-YLE-9V
Chemical type: Peptide, no natural source
Sequence: YLEPGPVTV
Assay category: TCell
Result: Positive
Quantitative measurement: 21900.0

Epitope: A2-YLE-9V
Chemical type: Peptide, no natural source
Sequence: YLEPGPVTV
Assay category: TCell
Result: Positive
Quantitative measurement: 2.02

Epitope: A2-YLE-9V
Chemical type: Peptide, no natural source
Sequence: YLEPGPVTV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.02

Epitope: A2-YLE-3A
Chemical type: Peptide, no natural source
Sequence: YLAPGPVTA
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-3A
Chemical type: Peptide, no natural source
Sequence: YLAPGPVTA
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-3A
Chemical type: Peptide, no natural source
Sequence: YLAPGPVTA
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-3A
Chemical type: Peptide, no natural source
Sequence: YLAPGPVTA
Assay category: TCell
Result: Negative

Epitope: A2-YLE-3A
Chemical type: Peptide, no natural source
Sequence: YLAPGPVTA
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.12

Epitope: A2-YLE-5A
Chemical type: Peptide, no natural source
Sequence: YLEPAPVTA
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-5A
Chemical type: Peptide, no natural source
Sequence: YLEPAPVTA
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-5A
Chemical type: Peptide, no natural source
Sequence: YLEPAPVTA
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-5A
Chemical type: Peptide, no natural source
Sequence: YLEPAPVTA
Assay category: TCell
Result: Negative
Quantitative measurement: 1000000.0

Epitope: A2-YLE-5A
Chemical type: Peptide, no natural source
Sequence: YLEPAPVTA
Assay category: TCell
Result: Negative
Quantitative measurement: 1000000.0

Epitope: A2-YLE-5A
Chemical type: Peptide, no natural source
Sequence: YLEPAPVTA
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.54

Epitope: A2-YLE-1A
Chemical type: Peptide, no natural source
Sequence: ALEPGPVTA
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-1A
Chemical type: Peptide, no natural source
Sequence: ALEPGPVTA
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-1A
Chemical type: Peptide, no natural source
Sequence: ALEPGPVTA
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-1A
Chemical type: Peptide, no natural source
Sequence: ALEPGPVTA
Assay category: TCell
Result: Positive
Quantitative measurement: 15900.0

Epitope: A2-YLE-1A
Chemical type: Peptide, no natural source
Sequence: ALEPGPVTA
Assay category: TCell
Result: Positive
Quantitative measurement: 60600.0

Epitope: A2-YLE-4A
Chemical type: Peptide, no natural source
Sequence: YLEAGPVTA
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-4A
Chemical type: Peptide, no natural source
Sequence: YLEAGPVTA
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-4A
Chemical type: Peptide, no natural source
Sequence: YLEAGPVTA
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-4A
Chemical type: Peptide, no natural source
Sequence: YLEAGPVTA
Assay category: TCell
Result: Positive
Quantitative measurement: 19700.0

Epitope: A2-YLE-4A
Chemical type: Peptide, no natural source
Sequence: YLEAGPVTA
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 144100.0

Epitope: A2-YLE-6A
Chemical type: Peptide, no natural source
Sequence: YLEPGAVTA
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-6A
Chemical type: Peptide, no natural source
Sequence: YLEPGAVTA
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-6A
Chemical type: Peptide, no natural source
Sequence: YLEPGAVTA
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-6A
Chemical type: Peptide, no natural source
Sequence: YLEPGAVTA
Assay category: TCell
Result: Positive
Quantitative measurement: 11400.0

Epitope: A2-YLE-6A
Chemical type: Peptide, no natural source
Sequence: YLEPGAVTA
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 954900.0

Epitope: A2-YLE-7A
Chemical type: Peptide, no natural source
Sequence: YLEPGPATA
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-7A
Chemical type: Peptide, no natural source
Sequence: YLEPGPATA
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-7A
Chemical type: Peptide, no natural source
Sequence: YLEPGPATA
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-7A
Chemical type: Peptide, no natural source
Sequence: YLEPGPATA
Assay category: TCell
Result: Positive
Quantitative measurement: 31100.0

Epitope: A2-YLE-7A
Chemical type: Peptide, no natural source
Sequence: YLEPGPATA
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 102000.0

Epitope: A2-YLE-8A
Chemical type: Peptide, no natural source
Sequence: YLEPGPVAA
Assay category: TCell
Result: Positive
Quantitative measurement: 38100.0

Epitope: A2-YLE-8A
Chemical type: Peptide, no natural source
Sequence: YLEPGPVAA
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 121000.0

Epitope: A2-YLE-8A
Chemical type: Peptide, no natural source
Sequence: YLEPGPVAA
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-8A
Chemical type: Peptide, no natural source
Sequence: YLEPGPVAA
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A2-YLE-8A
Chemical type: Peptide, no natural source
Sequence: YLEPGPVAA
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo