Reference: Cecily Choy; Joseph Chen; Jiangyuan Li; D Travis Gallagher; Jian Lu; Daichao Wu; Ainslee Zou; Humza Hemani; Beverly A Baptiste; Emily Wichmann; Qian Yang; Jeffrey Ciffelo; Rui Yin; Julia McKelvy; Denise Melvin; Tonya Wallace; Christopher Dunn; Cuong Nguyen; Chee W Chia; Jinshui Fan; Jeannie Ruffolo; Linda Zukley; Guixin Shi; Tomokazu Amano; Yang An; Osorio Meirelles; Wells W Wu; Chao-Kai Chou; Rong-Fong Shen; Richard A Willis; Minoru S H Ko; Yu-Tsueng Liu; Supriyo De; Brian G Pierce; Luigi Ferrucci; Josephine Egan; Roy Mariuzza; Nan-Ping Weng. "SARS-CoV-2 infection establishes a stable and age-independent CD8<sup>+</sup> T cell response against a dominant nucleocapsid epitope using restricted T cell receptors." Nature communications (2023).

Epitope: ALN
Chemical type: Peptide from protein
Sequence: ALNTPKDHI
Position: 138-146
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ALN
Chemical type: Peptide from protein
Sequence: ALNTPKDHI
Position: 138-146
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ALN
Chemical type: Peptide from protein
Sequence: ALNTPKDHI
Position: 138-146
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: ALN
Chemical type: Peptide from protein
Sequence: ALNTPKDHI
Position: 138-146
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LQL
Chemical type: Peptide from protein
Sequence: LQLPQGTTL
Position: 159-167
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LQL
Chemical type: Peptide from protein
Sequence: LQLPQGTTL
Position: 159-167
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LQL
Chemical type: Peptide from protein
Sequence: LQLPQGTTL
Position: 159-167
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LQL
Chemical type: Peptide from protein
Sequence: LQLPQGTTL
Position: 159-167
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LAL
Chemical type: Peptide from protein
Sequence: LALLLLDRL
Position: 219-227
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LAL
Chemical type: Peptide from protein
Sequence: LALLLLDRL
Position: 219-227
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LAL
Chemical type: Peptide from protein
Sequence: LALLLLDRL
Position: 219-227
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LLL
Chemical type: Peptide from protein
Sequence: LLLDRLNQL
Position: 222-230
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Quantitative measurement: 3.18

Epitope: LLL
Chemical type: Peptide from protein
Sequence: LLLDRLNQL
Position: 222-230
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Quantitative measurement: 0.34

Epitope: LLL
Chemical type: Peptide from protein
Sequence: LLLDRLNQL
Position: 222-230
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: LLL
Chemical type: Peptide from protein
Sequence: LLLDRLNQL
Position: 222-230
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Quantitative measurement: 17000.0

Epitope: LLL
Chemical type: Peptide from protein
Sequence: LLLDRLNQL
Position: 222-230
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: LLL
Chemical type: Peptide from protein
Sequence: LLLDRLNQL
Position: 222-230
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LLL
Chemical type: Peptide from protein
Sequence: LLLDRLNQL
Position: 222-230
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LLL
Chemical type: Peptide from protein
Sequence: LLLDRLNQL
Position: 222-230
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LLL
Chemical type: Peptide from protein
Sequence: LLLDRLNQL
Position: 222-230
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LLL
Chemical type: Peptide from protein
Sequence: LLLDRLNQL
Position: 222-230
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Quantitative measurement: 20400.0

Epitope: LLL
Chemical type: Peptide from protein
Sequence: LLLDRLNQL
Position: 222-230
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: LLL
Chemical type: Peptide from protein
Sequence: LLLDRLNQL
Position: 222-230
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: LLL
Chemical type: Peptide from protein
Sequence: LLLDRLNQL
Position: 222-230
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 3.18

Epitope: GMS
Chemical type: Peptide from protein
Sequence: GMSRIGMEV
Position: 316-324
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GMS
Chemical type: Peptide from protein
Sequence: GMSRIGMEV
Position: 316-324
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GMS
Chemical type: Peptide from protein
Sequence: GMSRIGMEV
Position: 316-324
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: ILL
Chemical type: Peptide from protein
Sequence: ILLNKHIDA
Position: 351-359
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ILL
Chemical type: Peptide from protein
Sequence: ILLNKHIDA
Position: 351-359
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ILL
Chemical type: Peptide from protein
Sequence: ILLNKHIDA
Position: 351-359
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: ILL
Chemical type: Peptide from protein
Sequence: ILLNKHIDA
Position: 351-359
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo