Reference: Christiane S Eberhardt; Haydn T Kissick; Mihir R Patel; Maria A Cardenas; Nataliya Prokhnevska; Rebecca C Obeng; Tahseen H Nasti; Christopher C Griffith; Se Jin Im; Xu Wang; Dong M Shin; Mary Carrington; Zhuo G Chen; John Sidney; Alessandro Sette; Nabil F Saba; Andreas Wieland; Rafi Ahmed. "Functional HPV-specific PD-1<sup>+</sup> stem-like CD8 T cells in head and neck cancer." Nature (2021).

Epitope: HPV E2 151-159
Chemical type: Peptide from protein
Sequence: QVDYYGLYY
Position: 151-159
Source molecule (GenBank): P03120.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E2 151-159
Chemical type: Peptide from protein
Sequence: QVDYYGLYY
Position: 151-159
Source molecule (GenBank): P03120.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E2 151-159
Chemical type: Peptide from protein
Sequence: QVDYYGLYY
Position: 151-159
Source molecule (GenBank): P03120.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E2 151-159
Chemical type: Peptide from protein
Sequence: QVDYYGLYY
Position: 151-159
Source molecule (GenBank): P03120.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: other
Culture conditions: Direct Ex Vivo

Epitope: HPV E2 151-159
Chemical type: Peptide from protein
Sequence: QVDYYGLYY
Position: 151-159
Source molecule (GenBank): P03120.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 18.0

Epitope: HPV E2 329-337
Chemical type: Peptide from protein
Sequence: KSAIVTLTY
Position: 329-337
Source molecule (GenBank): P03120.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E2 329-337
Chemical type: Peptide from protein
Sequence: KSAIVTLTY
Position: 329-337
Source molecule (GenBank): P03120.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E2 329-337
Chemical type: Peptide from protein
Sequence: KSAIVTLTY
Position: 329-337
Source molecule (GenBank): P03120.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E2 329-337
Chemical type: Peptide from protein
Sequence: KSAIVTLTY
Position: 329-337
Source molecule (GenBank): P03120.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: other
Culture conditions: Direct Ex Vivo

Epitope: HPV E2 329-337
Chemical type: Peptide from protein
Sequence: KSAIVTLTY
Position: 329-337
Source molecule (GenBank): P03120.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 11.0

Epitope: HPV E5 46-54
Chemical type: Peptide from protein
Sequence: VLLLWITAA
Position: 46-54
Source molecule (GenBank): AAD24028.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HPV E5 46-54
Chemical type: Peptide from protein
Sequence: VLLLWITAA
Position: 46-54
Source molecule (GenBank): AAD24028.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: other
Culture conditions: Direct Ex Vivo

Epitope: HPV E5 46-54
Chemical type: Peptide from protein
Sequence: VLLLWITAA
Position: 46-54
Source molecule (GenBank): AAD24028.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 11.0

Epitope: HPV E5 55-63
Chemical type: Peptide from protein
Sequence: SAFRCFIVY
Position: 55-63
Source molecule (GenBank): AAD24028.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E5 55-63
Chemical type: Peptide from protein
Sequence: SAFRCFIVY
Position: 55-63
Source molecule (GenBank): AAD24028.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E5 55-63
Chemical type: Peptide from protein
Sequence: SAFRCFIVY
Position: 55-63
Source molecule (GenBank): AAD24028.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E5 55-63
Chemical type: Peptide from protein
Sequence: SAFRCFIVY
Position: 55-63
Source molecule (GenBank): AAD24028.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 1.4

Epitope: HPV E5 65-73
Chemical type: Peptide from protein
Sequence: IFVYIPLFL
Position: 65-73
Source molecule (GenBank): AAD24036.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E5 65-73
Chemical type: Peptide from protein
Sequence: IFVYIPLFL
Position: 65-73
Source molecule (GenBank): AAD24036.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E5 65-73
Chemical type: Peptide from protein
Sequence: IFVYIPLFL
Position: 65-73
Source molecule (GenBank): AAD24036.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E5 65-73
Chemical type: Peptide from protein
Sequence: IFVYIPLFL
Position: 65-73
Source molecule (GenBank): AAD24036.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 444.0

Epitope: HPV E6 81-90
Chemical type: Peptide from protein
Sequence: SEYRHYCYSL
Position: 81-90
Source molecule (GenBank): P03126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E6 81-90
Chemical type: Peptide from protein
Sequence: SEYRHYCYSL
Position: 81-90
Source molecule (GenBank): P03126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E6 81-90
Chemical type: Peptide from protein
Sequence: SEYRHYCYSL
Position: 81-90
Source molecule (GenBank): P03126
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 0.54

Epitope: HPV E6 83-90
Chemical type: Peptide from protein
Sequence: YRHYCYSL
Position: 83-90
Source molecule (GenBank): P03126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E6 83-90
Chemical type: Peptide from protein
Sequence: YRHYCYSL
Position: 83-90
Source molecule (GenBank): P03126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E6 83-90
Chemical type: Peptide from protein
Sequence: YRHYCYSL
Position: 83-90
Source molecule (GenBank): P03126
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HPV E6 83-90
Chemical type: Peptide from protein
Sequence: YRHYCYSL
Position: 83-90
Source molecule (GenBank): P03126
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 12.0