Reference: Mario Hidalgo-Ruiz; Susana Mejia-López; Rosa M Pérez-Serrano; Guadalupe Zaldívar-Lelo de Larrea; Sabrina Ganzinelli; Monica Florin-Christensen; Carlos E Suarez; Rubén Hernández-Ortiz; Miguel A Mercado-Uriostegui; Angelina Rodríguez-Torres; Bertha I Carvajal-Gamez; Minerva Camacho-Nuez; Silvina E Wilkowsky; Juan Mosqueda. "Babesia bovis AMA-1, MSA-2c and RAP-1 contain conserved B and T-cell epitopes, which generate neutralizing antibodies and a long-lasting Th1 immune response in vaccinated cattle." Vaccine (2022).

Epitope: P1MSA
Chemical type: Peptide from protein
Sequence: VPTKQVNGS
Position: 28-36
Source molecule (GenBank): ADE20181.1
Assay category: BCell
Result: Negative

Epitope: P2MSA
Chemical type: Peptide from protein
Sequence: HDALKAVKQLIKTDAPFNTSDFDT
Position: 80-103
Source molecule (GenBank): ADE20181.1
Assay category: BCell
Result: Positive

Epitope: P3MSA
Chemical type: Peptide from protein
Sequence: FINPSST
Position: 209-215
Source molecule (GenBank): ADE20182.1
Assay category: BCell
Result: Positive

Epitope: P3MSA
Chemical type: Peptide from protein
Sequence: FINPSST
Position: 209-215
Source molecule (GenBank): ADE20182.1
Assay category: BCell
Result: Positive

Epitope: P3MSA
Chemical type: Peptide from protein
Sequence: FINPSST
Position: 209-215
Source molecule (GenBank): ADE20182.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P3MSA
Chemical type: Peptide from protein
Sequence: FINPSST
Position: 209-215
Source molecule (GenBank): ADE20182.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P4MSA
Chemical type: Peptide from protein
Sequence: GENTAAQPPQPAE
Position: 226-238
Source molecule (GenBank): ABR28477.1
Assay category: BCell
Result: Positive

Epitope: P4MSA
Chemical type: Peptide from protein
Sequence: GENTAAQPPQPAE
Position: 226-238
Source molecule (GenBank): ABR28477.1
Assay category: BCell
Result: Positive

Epitope: P4MSA
Chemical type: Peptide from protein
Sequence: GENTAAQPPQPAE
Position: 226-238
Source molecule (GenBank): ABR28477.1
Assay category: BCell
Result: Positive

Epitope: P4MSA
Chemical type: Peptide from protein
Sequence: GENTAAQPPQPAE
Position: 226-238
Source molecule (GenBank): ABR28477.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P4MSA
Chemical type: Peptide from protein
Sequence: GENTAAQPPQPAE
Position: 226-238
Source molecule (GenBank): ABR28477.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P1RAP
Chemical type: Peptide from protein
Sequence: QIVNDVCSNAPEDSNCREVV
Position: 74-93
Source molecule (GenBank): AAC27386.1
Assay category: BCell
Result: Positive-High

Epitope: P1RAP
Chemical type: Peptide from protein
Sequence: QIVNDVCSNAPEDSNCREVV
Position: 74-93
Source molecule (GenBank): AAC27386.1
Assay category: BCell
Result: Positive

Epitope: P2RAP
Chemical type: Peptide from protein
Sequence: NVKYPLYQEYQPLSLPNPYQL
Position: 110-130
Source molecule (GenBank): AAC27386.1
Assay category: BCell
Result: Positive

Epitope: P3RAP
Chemical type: Peptide from protein
Sequence: VVHEEGTTDVEYLV
Position: 177-190
Source molecule (GenBank): AAC27386.1
Assay category: BCell
Result: Positive-High

Epitope: P3RAP
Chemical type: Peptide from protein
Sequence: VVHEEGTTDVEYLV
Position: 177-190
Source molecule (GenBank): AAC27386.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P3RAP
Chemical type: Peptide from protein
Sequence: VVHEEGTTDVEYLV
Position: 177-190
Source molecule (GenBank): AAC27386.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P4RAP
Chemical type: Peptide from protein
Sequence: VTQPTKKFIEDTNEVTKNYLK
Position: 314-334
Source molecule (GenBank): AAC27386.1
Assay category: BCell
Result: Positive

Epitope: P4RAP
Chemical type: Peptide from protein
Sequence: VTQPTKKFIEDTNEVTKNYLK
Position: 314-334
Source molecule (GenBank): AAC27386.1
Assay category: BCell
Result: Positive-High

Epitope: P4RAP
Chemical type: Peptide from protein
Sequence: VTQPTKKFIEDTNEVTKNYLK
Position: 314-334
Source molecule (GenBank): AAC27386.1
Assay category: BCell
Result: Positive

Epitope: P4RAP
Chemical type: Peptide from protein
Sequence: VTQPTKKFIEDTNEVTKNYLK
Position: 314-334
Source molecule (GenBank): AAC27386.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P4RAP
Chemical type: Peptide from protein
Sequence: VTQPTKKFIEDTNEVTKNYLK
Position: 314-334
Source molecule (GenBank): AAC27386.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P5RAP
Chemical type: Peptide from protein
Sequence: TKKFMQDTHEKTKGYLKENVAEP
Position: 341-363
Source molecule (GenBank): AAC27386.1
Assay category: BCell
Result: Positive

Epitope: P5RAP
Chemical type: Peptide from protein
Sequence: TKKFMQDTHEKTKGYLKENVAEP
Position: 341-363
Source molecule (GenBank): AAC27386.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P5RAP
Chemical type: Peptide from protein
Sequence: TKKFMQDTHEKTKGYLKENVAEP
Position: 341-363
Source molecule (GenBank): AAC27386.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P2AMA-1
Chemical type: Peptide from protein
Sequence: QEYANSTEDCAAILFDNSATDL
Position: 328-349
Source molecule (GenBank): ACM44018.1
Assay category: BCell
Result: Positive

Epitope: P2AMA-1
Chemical type: Peptide from protein
Sequence: QEYANSTEDCAAILFDNSATDL
Position: 328-349
Source molecule (GenBank): ACM44018.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P2AMA-1
Chemical type: Peptide from protein
Sequence: QEYANSTEDCAAILFDNSATDL
Position: 328-349
Source molecule (GenBank): ACM44018.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo