Reference: Mattia Bonsignori; Tongqing Zhou; Zizhang Sheng; Lei Chen; Feng Gao; M Gordon Joyce; Gabriel Ozorowski; Gwo-Yu Chuang; Chaim A Schramm; Kevin Wiehe; S Munir Alam; Todd Bradley; Morgan A Gladden; Kwan-Ki Hwang; Sheelah Iyengar; Amit Kumar; Xiaozhi Lu; Kan Luo; Michael C Mangiapani; Robert J Parks; Hongshuo Song; Priyamvada Acharya; Robert T Bailer; Allen Cao; Aliaksandr Druz; Ivelin S Georgiev; Young D Kwon; Mark K Louder; Baoshan Zhang; Anqi Zheng; Brenna J Hill; Rui Kong; Cinque Soto; James C Mullikin; Daniel C Douek; David C Montefiori; Michael A Moody; George M Shaw; Beatrice H Hahn; Garnett Kelsoe; Peter T Hraber; Bette T Korber; Scott D Boyd; Andrew Z Fire; Thomas B Kepler; Lawrence Shapiro; Andrew B Ward; John R Mascola; Hua-Xin Liao; Peter D Kwong; Barton F Haynes. "Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody." Cell (2016).

Epitope: Epitope of CH325 Fab HIV-1 Env gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, E277, N278, L279, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, T449, R450, D451, G452, G453, N455, G465, G466, G467, K470, R474
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of CH325 Fab HIV-1 Env gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, E277, N278, L279, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, T449, R450, D451, G452, G453, N455, G465, G466, G467, K470, R474
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of CH325 Fab HIV-1 Env gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, E277, N278, L279, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, T449, R450, D451, G452, G453, N455, G465, G466, G467, K470, R474
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.89
Host: M

Epitope: Epitope of CH325 Fab HIV-1 Env gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, E277, N278, L279, T280, N281, N282, A283, K284, S365, G366, G367, D368, E370, I371, N419, M420, W421, T449, R450, D451, G452, G453, N455, G465, G466, G467, K470, R474
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of CH325.12 Fab HIV-1 Env gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, E277, N278, L279, T280, N281, N282, A283, K284, S365, G366, G367, D368, I371, G423, T449, R450, D451, G452, G453, R463, G466, R474
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of CH325.12 Fab HIV-1 Env gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, E277, N278, L279, T280, N281, N282, A283, K284, S365, G366, G367, D368, I371, G423, T449, R450, D451, G452, G453, R463, G466, R474
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive-High
Host: M

Epitope: Epitope of CH325.12 Fab HIV-1 Env gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, E277, N278, L279, T280, N281, N282, A283, K284, S365, G366, G367, D368, I371, G423, T449, R450, D451, G452, G453, R463, G466, R474
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of CH325.12 Fab HIV-1 Env gp120 core
Chemical type: Discontinuous protein residues
Discontinuous residues: W95, E277, N278, L279, T280, N281, N282, A283, K284, S365, G366, G367, D368, I371, G423, T449, R450, D451, G452, G453, R463, G466, R474
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.24
Host: M