Reference: Maria Alejandra Garcia-Marquez; Martin Thelen; Eugen Bauer; Lukas Maas; Kerstin Wennhold; Jonas Lehmann; Diandra Keller; Miloš Nikolić; Julie George; Thomas Zander; Wolfgang Schröder; Philipp Müller; Ali M Yazbeck; Christiane Bruns; Roman Thomas; Birgit Gathof; Alexander Quaas; Martin Peifer; Axel M Hillmer; Michael von Bergwelt-Baildon; Hans Anton Schlößer. "Germline homozygosity and allelic imbalance of HLA-I are common in esophagogastric adenocarcinoma and impair the repertoire of immunogenic peptides." Journal for immunotherapy of cancer (2024).

Epitope: Peptide 1
Chemical type: Peptide from protein
Sequence: MQAEGRGTGGSTGDA
Position: 1-15
Source molecule (GenBank): O75638.3
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 2
Chemical type: Peptide from protein
Sequence: GRGTGGSTGDADGPG
Position: 5-19
Source molecule (GenBank): O75638.3
Assay category: TCell
Result: Positive
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 3
Chemical type: Peptide from protein
Sequence: GGSTGDADGPGGPGI
Position: 9-23
Source molecule (GenBank): O75638.3
Assay category: TCell
Result: Positive
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 4
Chemical type: Peptide from protein
Sequence: GDADGPGGPGIPDGP
Position: 13-27
Source molecule (GenBank): O75638.3
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 6
Chemical type: Peptide from protein
Sequence: PGIPDGPGGNAGGPG
Position: 21-35
Source molecule (GenBank): O75638.3
Assay category: TCell
Result: Positive
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 7
Chemical type: Peptide from protein
Sequence: DGPGGNAGGPGEAGA
Position: 25-39
Source molecule (GenBank): O75638.3
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 8
Chemical type: Peptide from protein
Sequence: GNAGGPGEAGATGGR
Position: 29-43
Source molecule (GenBank): O75638.3
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 9
Chemical type: Peptide from protein
Sequence: GPGEAGATGGRGPRG
Position: 33-47
Source molecule (GenBank): O75638.3
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 10
Chemical type: Peptide from protein
Sequence: AGATGGRGPRGAGAA
Position: 37-51
Source molecule (GenBank): O75638.3
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 11
Chemical type: Peptide from protein
Sequence: GGRGPRGAGAARASG
Position: 41-55
Source molecule (GenBank): O75638.3
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 12
Chemical type: Peptide from protein
Sequence: PRGAGAARASGPGGG
Position: 45-59
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Positive
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 13
Chemical type: Peptide from protein
Sequence: GAARASGPGGGAPRG
Position: 49-63
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Positive
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 14
Chemical type: Peptide from protein
Sequence: ASGPGGGAPRGPHGG
Position: 53-67
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 15
Chemical type: Peptide from protein
Sequence: GGGAPRGPHGGAASG
Position: 57-71
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 17
Chemical type: Peptide from protein
Sequence: HGGAASGLNGCCRCG
Position: 65-79
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 19
Chemical type: Peptide from protein
Sequence: NGCCRCGARGPESRL
Position: 73-87
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 21
Chemical type: Peptide from protein
Sequence: RGPESRLLEFYLAMP
Position: 81-95
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Positive
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 23
Chemical type: Peptide from protein
Sequence: EFYLAMPFATPMEAE
Position: 89-103
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 24
Chemical type: Peptide from protein
Sequence: AMPFATPMEAELARR
Position: 93-107
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 25
Chemical type: Peptide from protein
Sequence: ATPMEAELARRSLAQ
Position: 97-111
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 26
Chemical type: Peptide from protein
Sequence: EAELARRSLAQDAPP
Position: 101-115
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 28
Chemical type: Peptide from protein
Sequence: LAQDAPPLPVPGVLL
Position: 109-123
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 29
Chemical type: Peptide from protein
Sequence: APPLPVPGVLLKEFT
Position: 113-127
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Positive
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 30
Chemical type: Peptide from protein
Sequence: PVPGVLLKEFTVSGN
Position: 117-131
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Positive
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 31
Chemical type: Peptide from protein
Sequence: VLLKEFTVSGNILTI
Position: 121-135
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 32
Chemical type: Peptide from protein
Sequence: EFTVSGNILTIRLTA
Position: 125-139
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 33
Chemical type: Peptide from protein
Sequence: SGNILTIRLTAADHR
Position: 129-143
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Positive
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 34
Chemical type: Peptide from protein
Sequence: LTIRLTAADHRQLQL
Position: 133-147
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Positive
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 35
Chemical type: Peptide from protein
Sequence: LTAADHRQLQLSISS
Position: 137-151
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 36
Chemical type: Peptide from protein
Sequence: DHRQLQLSISSCLQQ
Position: 141-155
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 37
Chemical type: Peptide from protein
Sequence: LQLSISSCLQQLSLL
Position: 145-159
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 38
Chemical type: Peptide from protein
Sequence: ISSCLQQLSLLMWIT
Position: 149-163
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Positive
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 39
Chemical type: Peptide from protein
Sequence: LQQLSLLMWITQCFL
Position: 153-167
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Positive
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 40
Chemical type: Peptide from protein
Sequence: SLLMWITQCFLPVFL
Position: 157-171
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 41
Chemical type: Peptide from protein
Sequence: WITQCFLPVFLAQPP
Position: 161-175
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Positive
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 42
Chemical type: Peptide from protein
Sequence: CFLPVFLAQPPSGQR
Position: 165-179
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Positive
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 43
Chemical type: Peptide from protein
Sequence: FLPVFLAQPPSGQRR
Position: 166-180
Source molecule (GenBank): P78358.1
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Pat#31 Pep. 1
Chemical type: Peptide, no natural source
Sequence: ALVGSRATSY
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: T cell
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: Pat#31 Pep. 1
Chemical type: Peptide, no natural source
Sequence: ALVGSRATSY
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Pat#31 Pep. 2
Chemical type: Peptide, no natural source
Sequence: SQRCESFLY
Assay category: TCell
Result: Positive
MHC allele types: 143 211 195 265 307 629
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Pat#31 Pep. 2
Chemical type: Peptide, no natural source
Sequence: SQRCESFLY
Assay category: TCell
Result: Positive
MHC allele types: 143 211 195 265 307 629
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Pat#31 Pep. 2
Chemical type: Peptide, no natural source
Sequence: SQRCESFLY
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: T cell
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: Pat#31 Pep. 4
Chemical type: Peptide, no natural source
Sequence: GVVGQSASF
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: T cell
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: Pat#31 Pep. 4
Chemical type: Peptide, no natural source
Sequence: GVVGQSASF
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Pat#31 Pep. 5
Chemical type: Peptide, no natural source
Sequence: DALQPLHEY
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: T cell
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: Pat#31 Pep. 5
Chemical type: Peptide, no natural source
Sequence: DALQPLHEY
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Pat#31 Pep. 6
Chemical type: Peptide, no natural source
Sequence: ALQPLHEYV
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Pat#31 Pep. 6
Chemical type: Peptide, no natural source
Sequence: ALQPLHEYV
Assay category: TCell
Result: Negative
MHC allele types: 143 211 195 265 307 629
Cell type: T cell
Tissue: blood
Culture conditions: Non-antigen specific activation