Reference: Ezra T Bekkering; Randy Yoo; Sophia Hailemariam; Fabian Heide; Danton Ivanochko; Matthew Jackman; Nicholas I Proellochs; Rianne Stoter; Geert-Jan van Gemert; Ayana Maeda; Takaaki Yuguchi; Oscar T Wanders; Renate C van Daalen; Maartje R Inklaar; Carolina M Andrade; Pascal W T C Jansen; Michiel Vermeulen; Teun Bousema; Eizo Takashima; John L Rubinstein; Taco W A Kooij; Matthijs M Jore; Jean-Philippe Julien. "Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity." Immunity (2025).

Epitope: Epitope of Fab RUPA-97 on Pfs230
Chemical type: Discontinuous protein residues
Discontinuous residues: D580, K581, Y582, A583, N585, C593, D594, F595, D597, Q598, K600, T602, E603, K609, C611, E612, K614, L635, K716
Source molecule (GenBank): P68874.1
Assay category: BCell
Result: Positive
Host: M 69 years

Epitope: Epitope of Fab RUPA-97 on Pfs230
Chemical type: Discontinuous protein residues
Discontinuous residues: D580, K581, Y582, A583, N585, C593, D594, F595, D597, Q598, K600, T602, E603, K609, C611, E612, K614, L635, K716
Source molecule (GenBank): P68874.1
Assay category: BCell
Result: Positive
Host: M 69 years

Epitope: Epitope of Fab RUPA-97 on Pfs230
Chemical type: Discontinuous protein residues
Discontinuous residues: D580, K581, Y582, A583, N585, C593, D594, F595, D597, Q598, K600, T602, E603, K609, C611, E612, K614, L635, K716
Source molecule (GenBank): P68874.1
Assay category: BCell
Result: Positive
Host: M 69 years

Epitope: Epitope of Fab RUPA-97 on Pfs230
Chemical type: Discontinuous protein residues
Discontinuous residues: D580, K581, Y582, A583, N585, C593, D594, F595, D597, Q598, K600, T602, E603, K609, C611, E612, K614, L635, K716
Source molecule (GenBank): P68874.1
Assay category: BCell
Result: Positive
Host: M 69 years

Epitope: Epitope of Fab RUPA-71 on Pfs45/48
Chemical type: Discontinuous protein residues
Discontinuous residues: K88, K89, S90, K101, Q104, Y126, E127, I128, E129, E130, N131, D132, T133, N134, P135
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Host: M 69 years

Epitope: Epitope of Fab RUPA-71 on Pfs45/48
Chemical type: Discontinuous protein residues
Discontinuous residues: K88, K89, S90, K101, Q104, Y126, E127, I128, E129, E130, N131, D132, T133, N134, P135
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Host: M 69 years

Epitope: Epitope of Fab RUPA-71 on Pfs45/48
Chemical type: Discontinuous protein residues
Discontinuous residues: K88, K89, S90, K101, Q104, Y126, E127, I128, E129, E130, N131, D132, T133, N134, P135
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Host: M 69 years

Epitope: Epitope of Fab RUPA-71 on Pfs45/48
Chemical type: Discontinuous protein residues
Discontinuous residues: K88, K89, S90, K101, Q104, Y126, E127, I128, E129, E130, N131, D132, T133, N134, P135
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Host: M 69 years

Epitope: Epitope of Fab RUPA-44 on Pfs45/48
Chemical type: Discontinuous protein residues
Discontinuous residues: D312, L314, L318, V319, D320, S322, A323, H324, S326, C327, N328, E362, E365
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Host: M 69 years

Epitope: Epitope of Fab RUPA-44 on Pfs45/48
Chemical type: Discontinuous protein residues
Discontinuous residues: D312, L314, L318, V319, D320, S322, A323, H324, S326, C327, N328, E362, E365
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Host: M 69 years

Epitope: Epitope of Fab RUPA-44 on Pfs45/48
Chemical type: Discontinuous protein residues
Discontinuous residues: D312, L314, L318, V319, D320, S322, A323, H324, S326, C327, N328, E362, E365
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Host: M 69 years

Epitope: Epitope of Fab RUPA-44 on Pfs45/48
Chemical type: Discontinuous protein residues
Discontinuous residues: D312, L314, L318, V319, D320, S322, A323, H324, S326, C327, N328, E362, E365
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Host: M 69 years

Epitope: Epitope of Fab LMIV230-01-97 on Pfs230
Chemical type: Discontinuous protein residues
Discontinuous residues: T567, E568, S569, G570, A573, E576, D577, Y579, K581, K653, E655, T656, K657, V701, Y703, E724, Y726
Source molecule (GenBank): P68874.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab LMIV230-01-97 on Pfs230
Chemical type: Discontinuous protein residues
Discontinuous residues: T567, E568, S569, G570, A573, E576, D577, Y579, K581, K653, E655, T656, K657, V701, Y703, E724, Y726
Source molecule (GenBank): P68874.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab LMIV230-01-97 on Pfs230
Chemical type: Discontinuous protein residues
Discontinuous residues: T567, E568, S569, G570, A573, E576, D577, Y579, K581, K653, E655, T656, K657, V701, Y703, E724, Y726
Source molecule (GenBank): P68874.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab LMIV230-01-97 on Pfs230
Chemical type: Discontinuous protein residues
Discontinuous residues: T567, E568, S569, G570, A573, E576, D577, Y579, K581, K653, E655, T656, K657, V701, Y703, E724, Y726
Source molecule (GenBank): P68874.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab LMIV230-01-97 on Pfs230
Chemical type: Discontinuous protein residues
Discontinuous residues: T567, E568, S569, G570, A573, E576, D577, Y579, K581, K653, E655, T656, K657, V701, Y703, E724, Y726
Source molecule (GenBank): P68874.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 18F25 on Pfs230
Chemical type: Discontinuous protein residues
Discontinuous residues: K1751, V1752, I1754, D1803, N1804, S1805, T1806, K1809, K1856
Source molecule (GenBank): P68874.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 18F25 on Pfs230
Chemical type: Discontinuous protein residues
Discontinuous residues: K1751, V1752, I1754, D1803, N1804, S1805, T1806, K1809, K1856
Source molecule (GenBank): P68874.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 18F25 on Pfs230
Chemical type: Discontinuous protein residues
Discontinuous residues: K1751, V1752, I1754, D1803, N1804, S1805, T1806, K1809, K1856
Source molecule (GenBank): P68874.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.8

Epitope: Epitope of Fab 18F25 on Pfs230
Chemical type: Discontinuous protein residues
Discontinuous residues: K1751, V1752, I1754, D1803, N1804, S1805, T1806, K1809, K1856
Source molecule (GenBank): P68874.1
Assay category: BCell
Result: Positive