Reference: Jason M Hogan; Peter S Lee; Susan C Wong; Sean M West; Winse H Morishige; Christine Bee; Gamze Camdere Tapia; Arvind Rajpal; Pavel Strop; Gavin Dollinger. "Residue-Level Characterization of Antibody Binding Epitopes Using Carbene Chemical Footprinting." Analytical chemistry (2023).

Epitope: Epitope of Fab-1 on MICA
Chemical type: Discontinuous protein residues
Discontinuous residues: R240, Q241, D242, G243, V244, S245, L246, S247, T250, C273, E276, Q278, R279, F280, Y283, H290, T292
Source molecule (GenBank): NP_001170990.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab-1 on MICA
Chemical type: Discontinuous protein residues
Discontinuous residues: R240, Q241, D242, G243, V244, S245, L246, S247, T250, C273, E276, Q278, R279, F280, Y283, H290, T292
Source molecule (GenBank): NP_001170990.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab-1 on MICA
Chemical type: Discontinuous protein residues
Discontinuous residues: R240, Q241, D242, G243, V244, S245, L246, S247, T250, C273, E276, Q278, R279, F280, Y283, H290, T292
Source molecule (GenBank): NP_001170990.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.4

Epitope: Epitope of Fab-2 on MICA
Chemical type: Discontinuous protein residues
Discontinuous residues: M183, R226, Y231, R233, N234, I235, I236, L237, T238, D242, G243, V244, S245, S247, H248, Q252, W253, L257, P258, D259, N261, G262, Y264, Q265, W267, R271, Q278, Y283, M284, E285
Source molecule (GenBank): NP_001170990.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab-2 on MICA
Chemical type: Discontinuous protein residues
Discontinuous residues: M183, R226, Y231, R233, N234, I235, I236, L237, T238, D242, G243, V244, S245, S247, H248, Q252, W253, L257, P258, D259, N261, G262, Y264, Q265, W267, R271, Q278, Y283, M284, E285
Source molecule (GenBank): NP_001170990.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab-3 on MICA
Chemical type: Discontinuous protein residues
Discontinuous residues: R29, L46, E120, S130, L139, N144, L145, E148, E149, W150, P153, Q159, L169, K170, H179
Source molecule (GenBank): NP_001170990.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab-3 on MICA
Chemical type: Discontinuous protein residues
Discontinuous residues: R29, L46, E120, S130, L139, N144, L145, E148, E149, W150, P153, Q159, L169, K170, H179
Source molecule (GenBank): NP_001170990.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab-3 on MICA
Chemical type: Discontinuous protein residues
Discontinuous residues: R29, L46, E120, S130, L139, N144, L145, E148, E149, W150, P153, Q159, L169, K170, H179
Source molecule (GenBank): NP_001170990.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab-4 on MICA
Chemical type: Discontinuous protein residues
Discontinuous residues: R29, M98, T99, D105, R117, V152, P153, S155, S156, R157, A158, Q159, T160, M163, N164, V165, R166, H179, H181, M183
Source molecule (GenBank): NP_001170990.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab-4 on MICA
Chemical type: Discontinuous protein residues
Discontinuous residues: R29, M98, T99, D105, R117, V152, P153, S155, S156, R157, A158, Q159, T160, M163, N164, V165, R166, H179, H181, M183
Source molecule (GenBank): NP_001170990.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab-5 on MICA
Chemical type: Discontinuous protein residues
Discontinuous residues: R29, V49, D105, R117, P153, S156, R157, Q159, T160, M163, N164, V165, R166, H179
Source molecule (GenBank): NP_001170990.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab-5 on MICA
Chemical type: Discontinuous protein residues
Discontinuous residues: R29, V49, D105, R117, P153, S156, R157, Q159, T160, M163, N164, V165, R166, H179
Source molecule (GenBank): NP_001170990.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab-6 on MICA
Chemical type: Discontinuous protein residues
Discontinuous residues: R29, N31, L32, V34, W37, V41, Q42, S43, G44, F45, L46, E48, F56, R58, Y59, R61, Q62, K63, R65, K67, L77, D83, G91, K94, R97, K104, D105, K107, E108, E115, Y135, P153, H179, Y194, W253
Source molecule (GenBank): NP_001170990.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab-6 on MICA
Chemical type: Discontinuous protein residues
Discontinuous residues: R29, N31, L32, V34, W37, V41, Q42, S43, G44, F45, L46, E48, F56, R58, Y59, R61, Q62, K63, R65, K67, L77, D83, G91, K94, R97, K104, D105, K107, E108, E115, Y135, P153, H179, Y194, W253
Source molecule (GenBank): NP_001170990.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab-6 on MICA
Chemical type: Discontinuous protein residues
Discontinuous residues: R29, N31, L32, V34, W37, V41, Q42, S43, G44, F45, L46, E48, F56, R58, Y59, R61, Q62, K63, R65, K67, L77, D83, G91, K94, R97, K104, D105, K107, E108, E115, Y135, P153, H179, Y194, W253
Source molecule (GenBank): NP_001170990.1
Assay category: BCell
Result: Positive