Reference: Daniela Latorre; Ulf Kallweit; Eric Armentani; Mathilde Foglierini; Federico Mele; Antonino Cassotta; Sandra Jovic; David Jarrossay; Johannes Mathis; Francesco Zellini; Burkhard Becher; Antonio Lanzavecchia; Ramin Khatami; Mauro Manconi; Mehdi Tafti; Claudio L Bassetti; Federica Sallusto. "T cells in patients with narcolepsy target self-antigens of hypocretin neurons." Nature (2018).

Epitope: HCRT 105-124
Chemical type: Peptide from protein
Sequence: PAPRPCLGRRCSAPAAASVA
Position: 105-124
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: F 16 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 17-36
Chemical type: Peptide from protein
Sequence: LLLLLLPPALLSSGAAAQPL
Position: 17-36
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host:  21 years, 25 years, or 44 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 113-127
Chemical type: Peptide from protein
Sequence: RRCSAPAAASVAPGG
Position: 113-127
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: F 21 and 44 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 49-78
Chemical type: Peptide from protein
Sequence: LYELLHGAGNHAAGILTLGKRRSGPPGLQG
Position: 49-78
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: M 21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 17-31
Chemical type: Peptide from protein
Sequence: LLLLLLPPALLSSGA
Position: 17-31
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: M 21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 81-95
Chemical type: Peptide from protein
Sequence: QRLLQASGNHAAGIL
Position: 81-95
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: M 21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 81-95
Chemical type: Peptide from protein
Sequence: QRLLQASGNHAAGIL
Position: 81-95
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: M 21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 73-87
Chemical type: Peptide from protein
Sequence: PPGLQGRLQRLLQAS
Position: 73-87
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: F 16 and 44 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 105-119
Chemical type: Peptide from protein
Sequence: PAPRPCLGRRCSAPA
Position: 105-119
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: M 21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 57-76
Chemical type: Peptide from protein
Sequence: GNHAAGILTLGKRRSGPPGL
Position: 57-76
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: M 38 and 48 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 97-116
Chemical type: Peptide from protein
Sequence: MGRRAGAEPAPRPCLGRRCS
Position: 97-116
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host:  38 and 44 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 73-92
Chemical type: Peptide from protein
Sequence: PPGLQGRLQRLLQASGNHAA
Position: 73-92
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: M 38 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 65-84
Chemical type: Peptide from protein
Sequence: TLGKRRSGPPGLQGRLQRLL
Position: 65-84
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: F 38 and 44 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 57-75
Chemical type: Peptide from protein
Sequence: GNHAAGILTLGKRRSGPPG
Position: 57-75
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: M 48 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 57-71
Chemical type: Peptide from protein
Sequence: GNHAAGILTLGKRRS
Position: 57-71
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: M 48 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 29-43
Chemical type: Peptide from protein
Sequence: SGAAAQPLPDCCRQK
Position: 29-43
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: M 48 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 69-87
Chemical type: Peptide from protein
Sequence: RRSGPPGLQGRLQRLLQAS
Position: 69-87
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: F 44 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 47-68
Chemical type: Peptide from protein
Sequence: CRLYELLHGAGNHAAGILTLGK
Position: 47-68
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: F 44 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 45-59
Chemical type: Peptide from protein
Sequence: CSCRLYELLHGAGNH
Position: 45-59
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: F 44 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 33-52
Chemical type: Peptide from protein
Sequence: AQPLPDCCRQKTCSCRLYEL
Position: 33-52
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: F 44 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 87-108
Chemical type: Peptide from protein
Sequence: SGNHAAGILTMGRRAGAEPAPR
Position: 87-108
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: F 44 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 25-44
Chemical type: Peptide from protein
Sequence: ALLSSGAAAQPLPDCCRQKT
Position: 25-44
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: F 21 and 44 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 69-91
Chemical type: Peptide from protein
Sequence: RRSGPPGLQGRLQRLLQASGNHA
Position: 69-91
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: F 44 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 9-28
Chemical type: Peptide from protein
Sequence: SWAAVTLLLLLLLLPPALLS
Position: 9-28
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: F 44 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 111-131
Chemical type: Peptide from protein
Sequence: LGRRCSAPAAASVAPGGQSGI
Position: 111-131
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: F 44 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 65-92
Chemical type: Peptide from protein
Sequence: TLGKRRSGPPGLQGRLQRLLQASGNHAA
Position: 65-92
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: F 44 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 69-97
Chemical type: Peptide from protein
Sequence: RRSGPPGLQGRLQRLLQASGNHAAGILTM
Position: 69-97
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: F 44 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 53-67
Chemical type: Peptide from protein
Sequence: LHGAGNHAAGILTLG
Position: 53-67
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: M 21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 85-99
Chemical type: Peptide from protein
Sequence: QASGNHAAGILTMGR
Position: 85-99
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: M 21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 33-47
Chemical type: Peptide from protein
Sequence: AQPLPDCCRQKTCSC
Position: 33-47
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: M 21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 69-95
Chemical type: Peptide from protein
Sequence: RRSGPPGLQGRLQRLLQASGNHAAGIL
Position: 69-95
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: M 21 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TRIB2 1-20
Chemical type: Peptide from protein
Sequence: MNIHRSTPITIARYGRSRNK
Position: 1-20
Source molecule (GenBank): Q92519.1
Assay category: TCell
Result: Positive
Host: M 28 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TRIB2 1-20
Chemical type: Peptide from protein
Sequence: MNIHRSTPITIARYGRSRNK
Position: 1-20
Source molecule (GenBank): Q92519.1
Assay category: TCell
Result: Positive
Host: M 28 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TRIB2 257-284
Chemical type: Peptide from protein
Sequence: IEPSSLFSKIRRGQFNIPETLSPKAKCL
Position: 257-284
Source molecule (GenBank): Q92519.1
Assay category: TCell
Result: Positive
Host: F 43 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TRIB2 177-196
Chemical type: Peptide from protein
Sequence: KLRKFIFKDEERTRVKLESL
Position: 177-196
Source molecule (GenBank): Q92519.1
Assay category: TCell
Result: Positive
Host: F 43 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TRIB2 153-172
Chemical type: Peptide from protein
Sequence: ARLFYQIASAVAHCHDGGLV
Position: 153-172
Source molecule (GenBank): Q92519.1
Assay category: TCell
Result: Positive
Host: M 25 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TRIB2 113-132
Chemical type: Peptide from protein
Sequence: INQITEIILGETKAYVFFER
Position: 113-132
Source molecule (GenBank): Q92519.1
Assay category: TCell
Result: Positive
Host: M 25 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TRIB2 185-212
Chemical type: Peptide from protein
Sequence: DEERTRVKLESLEDAYILRGDDDSLSDK
Position: 185-212
Source molecule (GenBank): Q92519.1
Assay category: TCell
Result: Positive
Host: M 25 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TRIB2 265-284
Chemical type: Peptide from protein
Sequence: KIRRGQFNIPETLSPKAKCL
Position: 265-284
Source molecule (GenBank): Q92519.1
Assay category: TCell
Result: Positive
Host: M 25 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TRIB2 49-68
Chemical type: Peptide from protein
Sequence: PETPNLSHCVSCIGKYLLLE
Position: 49-68
Source molecule (GenBank): Q92519.1
Assay category: TCell
Result: Positive
Host: M 25 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TRIB2 313-332
Chemical type: Peptide from protein
Sequence: SVSNSAYGAKEVSDQLVPDV
Position: 313-332
Source molecule (GenBank): Q92519.1
Assay category: TCell
Result: Positive
Host: M 25 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HCRT 97-124
Chemical type: Peptide from protein
Sequence: MGRRAGAEPAPRPCLGRRCSAPAAASVA
Position: 97-124
Source molecule (GenBank): EAW60810.1
Assay category: TCell
Result: Positive
Host: F 43 years
Cell type: T cell CD8+
Tissue: cerebrospinal fluid (CSF)
Culture conditions: Cell Line / Clone