Reference: Haonan Yang; Huimin Guo; Aojie Wang; Liwei Cao; Qing Fan; Jie Jiang; Miao Wang; Lin Lin; Xiangyang Ge; Haiyan Wang; Runze Zhang; Ming Liao; Renhong Yan; Bin Ju; Zheng Zhang. "Structural basis for the evolution and antibody evasion of SARS-CoV-2 BA.2.86 and JN.1 subvariants." Nature communications (2024).

Epitope: Epitope of S309 Fab on SARS-CoV-2 BA.2.86 S
Chemical type: Discontinuous protein residues
Discontinuous residues: N331, H336, E337, N340, A341, T342, R343, K437
Source molecule (GenBank): WMX20669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of S309 Fab on SARS-CoV-2 BA.2.86 S
Chemical type: Discontinuous protein residues
Discontinuous residues: N331, H336, E337, N340, A341, T342, R343, K437
Source molecule (GenBank): WMX20669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of S309 Fab on SARS-CoV-2 BA.2.86 S
Chemical type: Discontinuous protein residues
Discontinuous residues: N331, H336, E337, N340, A341, T342, R343, K437
Source molecule (GenBank): WMX20669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of S309 Fab on SARS-CoV-2 BA.2.86 S
Chemical type: Discontinuous protein residues
Discontinuous residues: N331, H336, E337, N340, A341, T342, R343, K437
Source molecule (GenBank): WMX20669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of S309 Fab on SARS-CoV-2 BA.2.86 S
Chemical type: Discontinuous protein residues
Discontinuous residues: N331, H336, E337, N340, A341, T342, R343, K437
Source molecule (GenBank): WMX20669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of S309 Fab on SARS-CoV-2 BA.2.86 S
Chemical type: Discontinuous protein residues
Discontinuous residues: N331, H336, E337, N340, A341, T342, R343, K437
Source molecule (GenBank): WMX20669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of S309 Fab on SARS-CoV-2 BA.2.86 S
Chemical type: Discontinuous protein residues
Discontinuous residues: N331, H336, E337, N340, A341, T342, R343, K437
Source molecule (GenBank): WMX20669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of S309 Fab on SARS-CoV-2 BA.2.86 S
Chemical type: Discontinuous protein residues
Discontinuous residues: N331, H336, E337, N340, A341, T342, R343, K437
Source molecule (GenBank): WMX20669.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of SA55 Fab on SARS-CoV-2 BA.2.86 S
Chemical type: Discontinuous protein residues
Discontinuous residues: F372, Q406, N414, N434, K437, T496, Y497, G498, V499, Y504
Source molecule (GenBank): WMX20669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SA55 Fab on SARS-CoV-2 BA.2.86 S
Chemical type: Discontinuous protein residues
Discontinuous residues: F372, Q406, N414, N434, K437, T496, Y497, G498, V499, Y504
Source molecule (GenBank): WMX20669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SA55 Fab on SARS-CoV-2 BA.2.86 S
Chemical type: Discontinuous protein residues
Discontinuous residues: F372, Q406, N414, N434, K437, T496, Y497, G498, V499, Y504
Source molecule (GenBank): WMX20669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SA55 Fab on SARS-CoV-2 BA.2.86 S
Chemical type: Discontinuous protein residues
Discontinuous residues: F372, Q406, N414, N434, K437, T496, Y497, G498, V499, Y504
Source molecule (GenBank): WMX20669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SA55 Fab on SARS-CoV-2 BA.2.86 S
Chemical type: Discontinuous protein residues
Discontinuous residues: F372, Q406, N414, N434, K437, T496, Y497, G498, V499, Y504
Source molecule (GenBank): WMX20669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SA55 Fab on SARS-CoV-2 BA.2.86 S
Chemical type: Discontinuous protein residues
Discontinuous residues: F372, Q406, N414, N434, K437, T496, Y497, G498, V499, Y504
Source molecule (GenBank): WMX20669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SA55 Fab on SARS-CoV-2 BA.2.86 S
Chemical type: Discontinuous protein residues
Discontinuous residues: F372, Q406, N414, N434, K437, T496, Y497, G498, V499, Y504
Source molecule (GenBank): WMX20669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SA55 Fab on SARS-CoV-2 BA.2.86 S
Chemical type: Discontinuous protein residues
Discontinuous residues: F372, Q406, N414, N434, K437, T496, Y497, G498, V499, Y504
Source molecule (GenBank): WMX20669.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb C118 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, S375, F377, K378, C379, Y380, G381, V382, S383, P384, T385, V407, R408, P412, G413, D427, D428, F429, T430, V503, G504
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb C118 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, S375, F377, K378, C379, Y380, G381, V382, S383, P384, T385, V407, R408, P412, G413, D427, D428, F429, T430, V503, G504
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb C118 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, S375, F377, K378, C379, Y380, G381, V382, S383, P384, T385, V407, R408, P412, G413, D427, D428, F429, T430, V503, G504
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb C118 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, S375, F377, K378, C379, Y380, G381, V382, S383, P384, T385, V407, R408, P412, G413, D427, D428, F429, T430, V503, G504
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb C118 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, S375, F377, K378, C379, Y380, G381, V382, S383, P384, T385, V407, R408, P412, G413, D427, D428, F429, T430, V503, G504
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb C118 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, S375, F377, K378, C379, Y380, G381, V382, S383, P384, T385, V407, R408, P412, G413, D427, D428, F429, T430, V503, G504
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb C118 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, S375, F377, K378, C379, Y380, G381, V382, S383, P384, T385, V407, R408, P412, G413, D427, D428, F429, T430, V503, G504
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb S2H97 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: W353, R355, R357, Y396, P426, D427, D428, F429, K462, P463, F464, R466, S514, E516, L518, H519, A520, P521
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb S2H97 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: W353, R355, R357, Y396, P426, D427, D428, F429, K462, P463, F464, R466, S514, E516, L518, H519, A520, P521
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb S2H97 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: W353, R355, R357, Y396, P426, D427, D428, F429, K462, P463, F464, R466, S514, E516, L518, H519, A520, P521
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb S2H97 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: W353, R355, R357, Y396, P426, D427, D428, F429, K462, P463, F464, R466, S514, E516, L518, H519, A520, P521
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb S2H97 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: W353, R355, R357, Y396, P426, D427, D428, F429, K462, P463, F464, R466, S514, E516, L518, H519, A520, P521
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb S2H97 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: W353, R355, R357, Y396, P426, D427, D428, F429, K462, P463, F464, R466, S514, E516, L518, H519, A520, P521
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb S2H97 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: W353, R355, R357, Y396, P426, D427, D428, F429, K462, P463, F464, R466, S514, E516, L518, H519, A520, P521
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb WRAIR-2057 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: R355, R457, S459, K462, P463, F464, E465, R466, D467, I468, S469, E471, Q474, P479, C480, N481, G482, L518
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb WRAIR-2057 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: R355, R457, S459, K462, P463, F464, E465, R466, D467, I468, S469, E471, Q474, P479, C480, N481, G482, L518
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb WRAIR-2057 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: R355, R457, S459, K462, P463, F464, E465, R466, D467, I468, S469, E471, Q474, P479, C480, N481, G482, L518
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb WRAIR-2057 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: R355, R457, S459, K462, P463, F464, E465, R466, D467, I468, S469, E471, Q474, P479, C480, N481, G482, L518
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb WRAIR-2057 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: R355, R457, S459, K462, P463, F464, E465, R466, D467, I468, S469, E471, Q474, P479, C480, N481, G482, L518
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb WRAIR-2057 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: R355, R457, S459, K462, P463, F464, E465, R466, D467, I468, S469, E471, Q474, P479, C480, N481, G482, L518
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb WRAIR-2057 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: R355, R457, S459, K462, P463, F464, E465, R466, D467, I468, S469, E471, Q474, P479, C480, N481, G482, L518
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb ION_300 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: W353, R355, Y396, R457, K462, P463, F464, E465, R466, D467, I468, E516, L518
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb ION_300 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: W353, R355, Y396, R457, K462, P463, F464, E465, R466, D467, I468, E516, L518
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb ION_300 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: W353, R355, Y396, R457, K462, P463, F464, E465, R466, D467, I468, E516, L518
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb ION_300 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: W353, R355, Y396, R457, K462, P463, F464, E465, R466, D467, I468, E516, L518
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb ION_300 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: W353, R355, Y396, R457, K462, P463, F464, E465, R466, D467, I468, E516, L518
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb ION_300 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: W353, R355, Y396, R457, K462, P463, F464, E465, R466, D467, I468, E516, L518
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb ION_300 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: W353, R355, Y396, R457, K462, P463, F464, E465, R466, D467, I468, E516, L518
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb S2K146 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: K417, Y449, L452, L455, F456, E484, G485, F486, N487, C488, Y489, F490, L492, Q493, S494, G496, Q498, N501, G502, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb S2K146 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: K417, Y449, L452, L455, F456, E484, G485, F486, N487, C488, Y489, F490, L492, Q493, S494, G496, Q498, N501, G502, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb S2K146 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: K417, Y449, L452, L455, F456, E484, G485, F486, N487, C488, Y489, F490, L492, Q493, S494, G496, Q498, N501, G502, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb S2K146 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: K417, Y449, L452, L455, F456, E484, G485, F486, N487, C488, Y489, F490, L492, Q493, S494, G496, Q498, N501, G502, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb S2K146 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: K417, Y449, L452, L455, F456, E484, G485, F486, N487, C488, Y489, F490, L492, Q493, S494, G496, Q498, N501, G502, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb N-612-056 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, A348, A352, W353, N354, R355, R357, Y396, R457, K462, F464, E465, R466, D467, I468, S469, T470, E471
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb N-612-056 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, A348, A352, W353, N354, R355, R357, Y396, R457, K462, F464, E465, R466, D467, I468, S469, T470, E471
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb N-612-056 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, A348, A352, W353, N354, R355, R357, Y396, R457, K462, F464, E465, R466, D467, I468, S469, T470, E471
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb N-612-056 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, A348, A352, W353, N354, R355, R357, Y396, R457, K462, F464, E465, R466, D467, I468, S469, T470, E471
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb N-612-056 on SARS-CoV-2  S
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, A348, A352, W353, N354, R355, R357, Y396, R457, K462, F464, E465, R466, D467, I468, S469, T470, E471
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate