Reference: Rui Wang; Jingni Wu; Yifeng Lin; Yufei Xiao; Bin Yang; Sheng Yao; Tianhui Pan; Zhixuan Fu; Shuyu Li; Caihua Wang; Yongliang Zhu. "An epitope-directed mRNA vaccine inhibits tumor metastasis through the blockade of MICA/B α1/2 shedding." Cell reports. Medicine (2025).

Epitope: Epitope of mAb MIA-2
Chemical type: Peptide from protein
Sequence: SHDTQQ
Position: 247-252
Source molecule (GenBank): AAH16929.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb MIA-2
Chemical type: Peptide from protein
Sequence: SHDTQQ
Position: 247-252
Source molecule (GenBank): AAH16929.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb MIA-2
Chemical type: Peptide from protein
Sequence: SHDTQQ
Position: 247-252
Source molecule (GenBank): AAH16929.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb MIA-2
Chemical type: Peptide from protein
Sequence: SHDTQQ
Position: 247-252
Source molecule (GenBank): AAH16929.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb MIA-2
Chemical type: Peptide from protein
Sequence: SHDTQQ
Position: 247-252
Source molecule (GenBank): AAH16929.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb MIA-2
Chemical type: Peptide from protein
Sequence: SHDTQQ
Position: 247-252
Source molecule (GenBank): AAH16929.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Ma3P
Chemical type: Peptide from protein
Sequence: SWRQDGVSLSHDTQQWGDVLPD
Position: 238-259
Source molecule (GenBank): AAH16929.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Ma3P
Chemical type: Peptide from protein
Sequence: SWRQDGVSLSHDTQQWGDVLPD
Position: 238-259
Source molecule (GenBank): AAH16929.1
Assay category: BCell
Result: Positive
Host: F 13 weeks

Epitope: Ma3P
Chemical type: Peptide from protein
Sequence: SWRQDGVSLSHDTQQWGDVLPD
Position: 238-259
Source molecule (GenBank): AAH16929.1
Assay category: BCell
Result: Positive
Host: F 13 weeks

Epitope: Ma3P
Chemical type: Peptide from protein
Sequence: SWRQDGVSLSHDTQQWGDVLPD
Position: 238-259
Source molecule (GenBank): AAH16929.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Ma3P
Chemical type: Peptide from protein
Sequence: SWRQDGVSLSHDTQQWGDVLPD
Position: 238-259
Source molecule (GenBank): AAH16929.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Ma3P
Chemical type: Peptide from protein
Sequence: SWRQDGVSLSHDTQQWGDVLPD
Position: 238-259
Source molecule (GenBank): AAH16929.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Ma3P
Chemical type: Peptide from protein
Sequence: SWRQDGVSLSHDTQQWGDVLPD
Position: 238-259
Source molecule (GenBank): AAH16929.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Ma3P
Chemical type: Peptide from protein
Sequence: SWRQDGVSLSHDTQQWGDVLPD
Position: 238-259
Source molecule (GenBank): AAH16929.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ma3P
Chemical type: Peptide from protein
Sequence: SWRQDGVSLSHDTQQWGDVLPD
Position: 238-259
Source molecule (GenBank): AAH16929.1
Assay category: TCell
Result: Positive
MHC allele types: 216 247
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ma3P
Chemical type: Peptide from protein
Sequence: SWRQDGVSLSHDTQQWGDVLPD
Position: 238-259
Source molecule (GenBank): AAH16929.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ma3P
Chemical type: Peptide from protein
Sequence: SWRQDGVSLSHDTQQWGDVLPD
Position: 238-259
Source molecule (GenBank): AAH16929.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Ma3P
Chemical type: Peptide from protein
Sequence: SWRQDGVSLSHDTQQWGDVLPD
Position: 238-259
Source molecule (GenBank): AAH16929.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo