Reference: Adi Vaknin-Dembinsky; Livnat Brill; Ibrahim Kassis; Panayiota Petrou; Haim Ovadia; Tamir Ben-Hur; Oded Abramsky; Dimitrios Karussis. "T-cell responses to distinct AQP4 peptides in patients with neuromyelitis optica (NMO)." Multiple sclerosis and related disorders (2016).

Epitope: AQP4 p54-68
Chemical type: Peptide from protein
Sequence: GSTINWGGTEKPLPV
Position: 54-68
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p54-68
Chemical type: Peptide from protein
Sequence: GSTINWGGTEKPLPV
Position: 54-68
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p54-68
Chemical type: Peptide from protein
Sequence: GSTINWGGTEKPLPV
Position: 54-68
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p59-72
Chemical type: Peptide from protein
Sequence: WGGTEKPLPVDMVL
Position: 59-72
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p59-72
Chemical type: Peptide from protein
Sequence: WGGTEKPLPVDMVL
Position: 59-72
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p59-72
Chemical type: Peptide from protein
Sequence: WGGTEKPLPVDMVL
Position: 59-72
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p137-151
Chemical type: Peptide from protein
Sequence: TPPSVVGGLGVTMVH
Position: 137-151
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p137-151
Chemical type: Peptide from protein
Sequence: TPPSVVGGLGVTMVH
Position: 137-151
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p137-151
Chemical type: Peptide from protein
Sequence: TPPSVVGGLGVTMVH
Position: 137-151
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p137-151
Chemical type: Peptide from protein
Sequence: TPPSVVGGLGVTMVH
Position: 137-151
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p137-151
Chemical type: Peptide from protein
Sequence: TPPSVVGGLGVTMVH
Position: 137-151
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p137-151
Chemical type: Peptide from protein
Sequence: TPPSVVGGLGVTMVH
Position: 137-151
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p137-151
Chemical type: Peptide from protein
Sequence: TPPSVVGGLGVTMVH
Position: 137-151
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p137-151
Chemical type: Peptide from protein
Sequence: TPPSVVGGLGVTMVH
Position: 137-151
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p137-151
Chemical type: Peptide from protein
Sequence: TPPSVVGGLGVTMVH
Position: 137-151
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p137-151
Chemical type: Peptide from protein
Sequence: TPPSVVGGLGVTMVH
Position: 137-151
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p137-151
Chemical type: Peptide from protein
Sequence: TPPSVVGGLGVTMVH
Position: 137-151
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p137-151
Chemical type: Peptide from protein
Sequence: TPPSVVGGLGVTMVH
Position: 137-151
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p137-151
Chemical type: Peptide from protein
Sequence: TPPSVVGGLGVTMVH
Position: 137-151
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p137-151
Chemical type: Peptide from protein
Sequence: TPPSVVGGLGVTMVH
Position: 137-151
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p137-151
Chemical type: Peptide from protein
Sequence: TPPSVVGGLGVTMVH
Position: 137-151
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p142-156
Chemical type: Peptide from protein
Sequence: VGGLGVTMVHGNLTA
Position: 142-156
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p142-156
Chemical type: Peptide from protein
Sequence: VGGLGVTMVHGNLTA
Position: 142-156
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p142-156
Chemical type: Peptide from protein
Sequence: VGGLGVTMVHGNLTA
Position: 142-156
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p147-161
Chemical type: Peptide from protein
Sequence: VTMVHGNLTAGHGLL
Position: 147-161
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p147-161
Chemical type: Peptide from protein
Sequence: VTMVHGNLTAGHGLL
Position: 147-161
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p147-161
Chemical type: Peptide from protein
Sequence: VTMVHGNLTAGHGLL
Position: 147-161
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p207-221
Chemical type: Peptide from protein
Sequence: YTGASMNPARSFGPA
Position: 207-221
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p207-221
Chemical type: Peptide from protein
Sequence: YTGASMNPARSFGPA
Position: 207-221
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p207-221
Chemical type: Peptide from protein
Sequence: YTGASMNPARSFGPA
Position: 207-221
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p212-226
Chemical type: Peptide from protein
Sequence: MNPARSFGPAVIMGN
Position: 212-226
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p212-226
Chemical type: Peptide from protein
Sequence: MNPARSFGPAVIMGN
Position: 212-226
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p212-226
Chemical type: Peptide from protein
Sequence: MNPARSFGPAVIMGN
Position: 212-226
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p217-231
Chemical type: Peptide from protein
Sequence: SFGPAVIMGNWENHW
Position: 217-231
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p217-231
Chemical type: Peptide from protein
Sequence: SFGPAVIMGNWENHW
Position: 217-231
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p217-231
Chemical type: Peptide from protein
Sequence: SFGPAVIMGNWENHW
Position: 217-231
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p222-236
Chemical type: Peptide from protein
Sequence: VIMGNWENHWIYWVG
Position: 222-236
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p222-236
Chemical type: Peptide from protein
Sequence: VIMGNWENHWIYWVG
Position: 222-236
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p222-236
Chemical type: Peptide from protein
Sequence: VIMGNWENHWIYWVG
Position: 222-236
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p222-236
Chemical type: Peptide from protein
Sequence: VIMGNWENHWIYWVG
Position: 222-236
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p222-236
Chemical type: Peptide from protein
Sequence: VIMGNWENHWIYWVG
Position: 222-236
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p222-236
Chemical type: Peptide from protein
Sequence: VIMGNWENHWIYWVG
Position: 222-236
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p222-236
Chemical type: Peptide from protein
Sequence: VIMGNWENHWIYWVG
Position: 222-236
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p222-236
Chemical type: Peptide from protein
Sequence: VIMGNWENHWIYWVG
Position: 222-236
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p222-236
Chemical type: Peptide from protein
Sequence: VIMGNWENHWIYWVG
Position: 222-236
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p222-236
Chemical type: Peptide from protein
Sequence: VIMGNWENHWIYWVG
Position: 222-236
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p222-236
Chemical type: Peptide from protein
Sequence: VIMGNWENHWIYWVG
Position: 222-236
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p222-236
Chemical type: Peptide from protein
Sequence: VIMGNWENHWIYWVG
Position: 222-236
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p222-236
Chemical type: Peptide from protein
Sequence: VIMGNWENHWIYWVG
Position: 222-236
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p222-236
Chemical type: Peptide from protein
Sequence: VIMGNWENHWIYWVG
Position: 222-236
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p222-236
Chemical type: Peptide from protein
Sequence: VIMGNWENHWIYWVG
Position: 222-236
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p259-273
Chemical type: Peptide from protein
Sequence: KRRFKEAFSKAAQQT
Position: 259-273
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p259-273
Chemical type: Peptide from protein
Sequence: KRRFKEAFSKAAQQT
Position: 259-273
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p259-273
Chemical type: Peptide from protein
Sequence: KRRFKEAFSKAAQQT
Position: 259-273
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p269-283
Chemical type: Peptide from protein
Sequence: AAQQTKGSYMEVEDN
Position: 269-283
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p269-283
Chemical type: Peptide from protein
Sequence: AAQQTKGSYMEVEDN
Position: 269-283
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p269-283
Chemical type: Peptide from protein
Sequence: AAQQTKGSYMEVEDN
Position: 269-283
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p279-283
Chemical type: Peptide from protein
Sequence: EVEDNRSQVETDDLI
Position: 279-293
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p279-283
Chemical type: Peptide from protein
Sequence: EVEDNRSQVETDDLI
Position: 279-293
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p279-283
Chemical type: Peptide from protein
Sequence: EVEDNRSQVETDDLI
Position: 279-293
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p289-303
Chemical type: Peptide from protein
Sequence: TDDLILKPGVVHVID
Position: 289-303
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p289-303
Chemical type: Peptide from protein
Sequence: TDDLILKPGVVHVID
Position: 289-303
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p289-303
Chemical type: Peptide from protein
Sequence: TDDLILKPGVVHVID
Position: 289-303
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p299-313
Chemical type: Peptide from protein
Sequence: VHVIDVDRGEEKKGK
Position: 299-313
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p299-313
Chemical type: Peptide from protein
Sequence: VHVIDVDRGEEKKGK
Position: 299-313
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p299-313
Chemical type: Peptide from protein
Sequence: VHVIDVDRGEEKKGK
Position: 299-313
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p309-323
Chemical type: Peptide from protein
Sequence: EKKGKDQSGEVLSSV
Position: 309-323
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host:  20-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p309-323
Chemical type: Peptide from protein
Sequence: EKKGKDQSGEVLSSV
Position: 309-323
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AQP4 p309-323
Chemical type: Peptide from protein
Sequence: EKKGKDQSGEVLSSV
Position: 309-323
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo