Reference: Priyanka Chaurasia; Thi H O Nguyen; Louise C Rowntree; Jennifer A Juno; Adam K Wheatley; Stephen J Kent; Katherine Kedzierska; Jamie Rossjohn; Jan Petersen. "Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein." The Journal of biological chemistry (2021).

Epitope: HLA-A2 S 269-277 epitope
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HLA-A2 S 269-277 epitope
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive
Quantitative measurement: 3720.0

Epitope: HLA-A2 S 269-277 epitope
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 109300.0

Epitope: HLA-A2 S 269-277 epitope
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Negative
Quantitative measurement: 100000.0

Epitope: HLA-A2 S 269-277 epitope
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive
Quantitative measurement: 2750.0

Epitope: HLA-A2 S 269-277 epitope
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 272400.0

Epitope: HLA-A2 S 269-277 epitope
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive
Quantitative measurement: 3.2

Epitope: HLA-A2 S 269-277 epitope
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive
Quantitative measurement: 2710.0

Epitope: HLA-A2 S 269-277 epitope
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 77600.0

Epitope: HLA-A2 S 269-277 epitope
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive
Quantitative measurement: 2360.0

Epitope: HLA-A2 S 269-277 epitope
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): YP_009724390.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.3

Epitope: S 269-277 P272L
Chemical type: Peptide from protein
Sequence: YLQLRTFLL
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S 269-277 P272L
Chemical type: Peptide from protein
Sequence: YLQLRTFLL
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 157500.0

Epitope: S 269-277 P272L
Chemical type: Peptide from protein
Sequence: YLQLRTFLL
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 163100.0

Epitope: S 269-277 P272L
Chemical type: Peptide from protein
Sequence: YLQLRTFLL
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 170200.0

Epitope: S 269-277 P272L
Chemical type: Peptide from protein
Sequence: YLQLRTFLL
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 272400.0

Epitope: S 269-277 R273S
Chemical type: Peptide from protein
Sequence: YLQPSTFLL
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S 269-277 T274I
Chemical type: Peptide from protein
Sequence: YLQPRIFLL
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S 269-277 T274I
Chemical type: Peptide from protein
Sequence: YLQPRIFLL
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 109300.0

Epitope: S 269-277 T274I
Chemical type: Peptide from protein
Sequence: YLQPRIFLL
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 360300.0

Epitope: PNRL
Chemical type: Peptide from protein
Sequence: YLQQRTFLL
Position: 269-277
Source molecule (GenBank): QIQ54048.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PNRL
Chemical type: Peptide from protein
Sequence: YLQQRTFLL
Position: 269-277
Source molecule (GenBank): QIQ54048.1
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 77600.0

Epitope: PNRL
Chemical type: Peptide from protein
Sequence: YLQQRTFLL
Position: 269-277
Source molecule (GenBank): QIQ54048.1
Assay category: TCell
Result: Positive
Quantitative measurement: 5870.0

Epitope: BTRL
Chemical type: Peptide from protein
Sequence: YLKPRTFML
Position: 265-273
Source molecule (GenBank): QSQ01650.1
Assay category: TCell
Result: Negative
Quantitative measurement: 100000.0

Epitope: BTRL
Chemical type: Peptide from protein
Sequence: YLKPRTFML
Position: 265-273
Source molecule (GenBank): QSQ01650.1
Assay category: TCell
Result: Negative
Quantitative measurement: 100000.0