Reference: Michael Schoof; Bryan Faust; Reuben A Saunders; Smriti Sangwan; Veronica Rezelj; Nick Hoppe; Morgane Boone; Christian B Billesbølle; Cristina Puchades; Caleigh M Azumaya; Huong T Kratochvil; Marcell Zimanyi; Ishan Deshpande; Jiahao Liang; Sasha Dickinson; Henry C Nguyen; Cynthia M Chio; Gregory E Merz; Michael C Thompson; Devan Diwanji; Kaitlin Schaefer; Aditya A Anand; Niv Dobzinski; Beth Shoshana Zha; Camille R Simoneau; Kristoffer Leon; Kris M White; Un Seng Chio; Meghna Gupta; Mingliang Jin; Fei Li; Yanxin Liu; Kaihua Zhang; David Bulkley; Ming Sun; Amber M Smith; Alexandrea N Rizo; Frank Moss; Axel F Brilot; Sergei Pourmal; Raphael Trenker; Thomas Pospiech; Sayan Gupta; Benjamin Barsi-Rhyne; Vladislav Belyy; Andrew W Barile-Hill; Silke Nock; Yuwei Liu; Nevan J Krogan; Corie Y Ralston; Danielle L Swaney; Adolfo García-Sastre; Melanie Ott; Marco Vignuzzi; Peter Walter; Aashish Manglik. "An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike." Science (New York, N.Y.) (2020).

Epitope: Epitope of Nb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, L492, Q493, S494, Y495, G496, Q498, N501, Y505; C: F342, N343, S371, S373, W436, N440
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 41.0

Epitope: Epitope of Nb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, L492, Q493, S494, Y495, G496, Q498, N501, Y505; C: F342, N343, S371, S373, W436, N440
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 270000.0

Epitope: Epitope of Nb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, L492, Q493, S494, Y495, G496, Q498, N501, Y505; C: F342, N343, S371, S373, W436, N440
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.056

Epitope: Epitope of Nb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, L492, Q493, S494, Y495, G496, Q498, N501, Y505; C: F342, N343, S371, S373, W436, N440
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2100000.0

Epitope: Epitope of Nb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, L492, Q493, S494, Y495, G496, Q498, N501, Y505; C: F342, N343, S371, S373, W436, N440
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.087

Epitope: Epitope of Nb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, L492, Q493, S494, Y495, G496, Q498, N501, Y505; C: F342, N343, S371, S373, W436, N440
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, L492, Q493, S494, Y495, G496, Q498, N501, Y505; C: F342, N343, S371, S373, W436, N440
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, L492, Q493, S494, Y495, G496, Q498, N501, Y505; C: F342, N343, S371, S373, W436, N440
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, L492, Q493, S494, Y495, G496, Q498, N501, Y505; C: F342, N343, S371, S373, W436, N440
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, L492, Q493, S494, Y495, G496, Q498, N501, Y505; C: F342, N343, S371, S373, W436, N440
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, L492, Q493, S494, Y495, G496, Q498, N501, Y505; C: F342, N343, S371, S373, W436, N440
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 210.0

Epitope: Epitope of mNb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R403, K417, G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, Q493, S494, Y495, G496, Q498, Y505; C: A372, S373, F374, N439, N440, P499, T500, V503
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00064

Epitope: Epitope of mNb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R403, K417, G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, Q493, S494, Y495, G496, Q498, Y505; C: A372, S373, F374, N439, N440, P499, T500, V503
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mNb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R403, K417, G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, Q493, S494, Y495, G496, Q498, Y505; C: A372, S373, F374, N439, N440, P499, T500, V503
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mNb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R403, K417, G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, Q493, S494, Y495, G496, Q498, Y505; C: A372, S373, F374, N439, N440, P499, T500, V503
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.45

Epitope: Epitope of mNb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R403, K417, G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, Q493, S494, Y495, G496, Q498, Y505; C: A372, S373, F374, N439, N440, P499, T500, V503
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1000000.0

Epitope: Epitope of mNb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R403, K417, G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, Q493, S494, Y495, G496, Q498, Y505; C: A372, S373, F374, N439, N440, P499, T500, V503
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00045

Epitope: Epitope of mNb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R403, K417, G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, Q493, S494, Y495, G496, Q498, Y505; C: A372, S373, F374, N439, N440, P499, T500, V503
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.56

Epitope: Epitope of mNb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R403, K417, G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, Q493, S494, Y495, G496, Q498, Y505; C: A372, S373, F374, N439, N440, P499, T500, V503
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1100000.0

Epitope: Epitope of mNb6 on SARS-CoV-2 S
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R403, K417, G446, Y449, L455, F456, V483, E484, G485, F486, Y489, F490, Q493, S494, Y495, G496, Q498, Y505; C: A372, S373, F374, N439, N440, P499, T500, V503
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive