Reference: S Urbani; J Uggeri; Y Matsuura; T Miyamura; A Penna; C Boni; C Ferrari. "Identification of immunodominant hepatitis C virus (HCV)-specific cytotoxic T-cell epitopes by stimulation with endogenously synthesized HCV antigens." Hepatology (Baltimore, Md.) (2001).

Epitope: Core.29-37
Chemical type: Peptide from protein
Sequence: QIVGGVYLL
Position: 29-37
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core.132-140
Chemical type: Peptide from protein
Sequence: DLMGYIPLV
Position: 132-140
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core.136-144
Chemical type: Peptide from protein
Sequence: YIPLVGAPL
Position: 136-144
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core.177-185
Chemical type: Peptide from protein
Sequence: FLLALLSCL
Position: 177-185
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core.35-44
Chemical type: Peptide from protein
Sequence: YLLPRRGPRL
Position: 35-44
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core.133-142
Chemical type: Peptide from protein
Sequence: LMGYIPLVGA
Position: 133-142
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core.181-189
Chemical type: Peptide from protein
Sequence: LLSCLTVPA
Position: 181-189
Source molecule (GenBank): BAA00705.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E1.268-277
Chemical type: Peptide from protein
Sequence: SATLCSALYV
Position: 268-277
Source molecule (GenBank): BAA00705.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E1.283-293
Chemical type: Peptide from protein
Sequence: SVFLVGQLFT
Position: 107-116
Source molecule (GenBank): AAD21270.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E1.323-331
Chemical type: Peptide from protein
Sequence: MMNWSPTTA
Position: 323-331
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E1.336-344
Chemical type: Peptide from protein
Sequence: QLLRIPQAI
Position: 336-344
Source molecule (GenBank): BAA00705.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E1.331-340
Chemical type: Peptide from protein
Sequence: ALVMAQLLRI
Position: 331-340
Source molecule (GenBank): BAA00705.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E1.364-372
Chemical type: Peptide from protein
Sequence: MVGNWAKVL
Position: 364-372
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E1.370-379
Chemical type: Peptide from protein
Sequence: KVLVVLLLFA
Position: 370-379
Source molecule (GenBank): BAA00705.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E1.373-381
Chemical type: Peptide from protein
Sequence: VVLLLFAGV
Position: 373-381
Source molecule (GenBank): BAA00705.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E1.375-383
Chemical type: Peptide from protein
Sequence: LLLFAGVDA
Position: 375-383
Source molecule (GenBank): BAA00705.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E1.371-379
Chemical type: Peptide from protein
Sequence: VLVVLLLFA
Position: 371-379
Source molecule (GenBank): BAA00705.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E2.400-408
Chemical type: Peptide from protein
Sequence: FVSLLAPGA
Position: 399-407
Source molecule (GenBank): AAA45676.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E2.565-573
Chemical type: Peptide from protein
Sequence: KVCGAPPCV
Position: 564-572
Source molecule (GenBank): AAY82019.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E2.612-620
Chemical type: Peptide from protein
Sequence: CLVDYPYRL
Position: 607-615
Source molecule (GenBank): AAY82030.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E2.678-687
Chemical type: Peptide from protein
Sequence: QVLPCSFTTL
Position: 673-682
Source molecule (GenBank): AAY82055.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E2.689-697
Chemical type: Peptide from protein
Sequence: ALSTGLIHL
Position: 684-692
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E2.694-702
Chemical type: Peptide from protein
Sequence: LIHLHQNIV
Position: 689-697
Source molecule (GenBank): AAY82055.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3.1044-1052
Chemical type: Peptide from protein
Sequence: LLGCIITSL
Position: 1039-1047
Source molecule (GenBank): AAY82030.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3.1084-1092
Chemical type: Peptide from protein
Sequence: WTVYHGQGT
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3.1136-1144
Chemical type: Peptide from protein
Sequence: YLVTRHADV
Position: 1131-1139
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3.1043-1052
Chemical type: Peptide from protein
Sequence: GLLGCIITSL
Position: 1038-1047
Source molecule (GenBank): AAY82030.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3.1173-1181
Chemical type: Peptide from protein
Sequence: PLLCPAGHA
Position: 1168-1176
Source molecule (GenBank): AAY82030.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3.1174-1182
Chemical type: Peptide from protein
Sequence: LLCPAGHAV
Position: 1169-1177
Source molecule (GenBank): AAY82030.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3.1255-1263
Chemical type: Peptide from protein
Sequence: KVLVLNPSV
Position: 1250-1258
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3.1256-1264
Chemical type: Peptide from protein
Sequence: VLVLNPSVA
Position: 1251-1259
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3.1520-1528
Chemical type: Peptide from protein
Sequence: VLCECYDA
Position: 1516-1523
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3.1545-1553
Chemical type: Peptide from protein
Sequence: RAYMNTPGL
Position: 1540-1548
Source molecule (GenBank): AAY82030.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1653-1661
Chemical type: Peptide from protein
Sequence: CMSADLEVV
Position: 1648-1656
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1650-1658
Chemical type: Peptide from protein
Sequence: IMTCMSADL
Position: 1195-1203
Source molecule (GenBank): AAA45677.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1660-1668
Chemical type: Peptide from protein
Sequence: VVTSTWVLV
Position: 1655-1663
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1665-1673
Chemical type: Peptide from protein
Sequence: WVLVGGVLA
Position: 1660-1668
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1649-1658
Chemical type: Peptide from protein
Sequence: YIMTCMSADL
Position: 1644-1653
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1665-1674
Chemical type: Peptide from protein
Sequence: WVLVGGVLAA
Position: 1660-1669
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1674-1682
Chemical type: Peptide from protein
Sequence: ALAAYCLST
Position: 1669-1677
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1676-1685
Chemical type: Peptide from protein
Sequence: AAYCLSTGCV
Position: 1671-1680
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1692-1700
Chemical type: Peptide from protein
Sequence: VLSGKPAII
Position: 1687-1695
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1769-1777
Chemical type: Peptide from protein
Sequence: HMWNFISGI
Position: 1764-1772
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1773-1789
Chemical type: Peptide from protein
Sequence: FISGIQYLA
Position: 1768-1776
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1785-1793
Chemical type: Peptide from protein
Sequence: TLPGNPAIA
Position: 1780-1788
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1791-1799
Chemical type: Peptide from protein
Sequence: AIASMLMAFT
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1794-1802
Chemical type: Peptide from protein
Sequence: SLMAFTAAV
Position: 1789-1797
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1791-1800
Chemical type: Peptide from protein
Sequence: AIASMLMAFTA
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1890-1898
Chemical type: Peptide from protein
Sequence: AILSPGALV
Position: 1885-1893
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1891-1899
Chemical type: Peptide from protein
Sequence: ILSPGALVV
Position: 1886-1894
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1896-1904
Chemical type: Peptide from protein
Sequence: ALVVGVVCA
Position: 1891-1899
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1981-1989
Chemical type: Peptide from protein
Sequence: WLRDIWDWI
Position: 1976-1984
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1984-1992
Chemical type: Peptide from protein
Sequence: DIWDWICEV
Position: 1979-1987
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1992-2000
Chemical type: Peptide from protein
Sequence: VLSDFKTWL
Position: 1987-1995
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.2003-2011
Chemical type: Peptide from protein
Sequence: KLMPQLPGI
Position: 1998-2006
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1973-1982
Chemical type: Peptide from protein
Sequence: STTPCSGSWL
Position: 1968-1977
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1611-1619
Chemical type: Peptide from protein
Sequence: QMWKCLIRL
Position: 1606-1614
Source molecule (GenBank): AAY82030.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1622-1630
Chemical type: Peptide from protein
Sequence: TLHGPTPLL
Position: 1617-1625
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1856-1864
Chemical type: Peptide from protein
Sequence: ILAGYGAGV
Position: 1401-1409
Source molecule (GenBank): AAA45677.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1873-1881
Chemical type: Peptide from protein
Sequence: IMSGEVPST
Position: 1418-1426
Source molecule (GenBank): AAA45677.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1920-1928
Chemical type: Peptide from protein
Sequence: WMNRLIAFA
Position: 1915-1923
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1812-1821
Chemical type: Peptide from protein
Sequence: LLFNILGGWV
Position: 1807-1816
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1838-1847
Chemical type: Peptide from protein
Sequence: GLAGAAIGSV
Position: 1383-1392
Source molecule (GenBank): AAA45677.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1856-1865
Chemical type: Peptide from protein
Sequence: ILAGYGAGVA
Position: 1851-1860
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5A.2059-2067
Chemical type: Peptide from protein
Sequence: NMWSGTFPI
Position: 1604-1612
Source molecule (GenBank): AAA45677.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5A.2153-2161
Chemical type: Peptide from protein
Sequence: RVGLHEYPV
Position: 1698-1706
Source molecule (GenBank): AAA45677.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5A.2178-2186
Chemical type: Peptide from protein
Sequence: SMLTDPSHI
Position: 2173-2181
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5A.2179-2187
Chemical type: Peptide from protein
Sequence: MLTDPSHIT
Position: 2174-2182
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5A.2195-2203
Chemical type: Peptide from protein
Sequence: LARGSPPSV
Position: 1740-1748
Source molecule (GenBank): AAA45677.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5A.2261-2269
Chemical type: Peptide from protein
Sequence: ILDSFDPLV
Position: 2252-2260
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5A.2145-2154
Chemical type: Peptide from protein
Sequence: LLREEVSFRV
Position: 2140-2149
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: E1.220-227
Chemical type: Peptide from protein
Sequence: ILHTPGCV
Position: 220-227
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3.402-412
Chemical type: Peptide from protein
Sequence: SLLAPGAKQNV
Position: 401-411
Source molecule (GenBank): AAA45676.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3.1073-1081
Chemical type: Peptide from protein
Sequence: CINGVCWTTV
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3.1287-1296
Chemical type: Peptide from protein
Sequence: TGAPVTYSTY
Position: 1287-1296
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1406-1415
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4.1671-1680
Chemical type: Peptide from protein
Sequence: VLAALAAYCL
Position: 1666-1675
Source molecule (GenBank): P29846.3
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated