Reference: M C Honeyman; N L Stone; L C Harrison. "T-cell epitopes in type 1 diabetes autoantigen tyrosine phosphatase IA-2: potential for mimicry with rotavirus and other environmental agents." Molecular medicine (Cambridge, Mass.) (1998).

Epitope: 685
Chemical type: Peptide from protein
Sequence: ANMDISTGHMILAYME
Position: 685-700
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 685
Chemical type: Peptide from protein
Sequence: ANMDISTGHMILAYME
Position: 685-700
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 9.0

Epitope: 713
Chemical type: Peptide from protein
Sequence: WQALCAYQAEPNTCAT
Position: 713-728
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 745
Chemical type: Peptide from protein
Sequence: PYDHARIKLKVESSPS
Position: 745-760
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 787
Chemical type: Peptide from protein
Sequence: LSHTIADFWQMVWESG
Position: 787-802
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 787
Chemical type: Peptide from protein
Sequence: LSHTIADFWQMVWESG
Position: 787-802
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 9.0

Epitope: 799
Chemical type: Peptide from protein
Sequence: WESGCTVIVMLTPLVE
Position: 799-814
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
MHC allele types: 341 340
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 841
Chemical type: Peptide from protein
Sequence: SEHIWCEDFLVRSFYL
Position: 841-856
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
MHC allele types: 341 340
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 841
Chemical type: Peptide from protein
Sequence: SEHIWCEDFLVRSFYL
Position: 841-856
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 9.0

Epitope: 845
Chemical type: Peptide from protein
Sequence: WCEDFLVRSFYLKNVQ
Position: 845-860
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 847
Chemical type: Peptide from protein
Sequence: EDFLVRSFYLKNVQTQ
Position: 847-862
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
MHC allele types: 341 340
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 889
Chemical type: Peptide from protein
Sequence: DFRRKVNKCYRGRSCP
Position: 889-904
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
MHC allele types: 341 340
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 959
Chemical type: Peptide from protein
Sequence: FEFALTAVAEEVNAIL
Position: 959-974
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 959
Chemical type: Peptide from protein
Sequence: FEFALTAVAEEVNAIL
Position: 959-974
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.0

Chemical type: Peptide from protein
Sequence: RQHARQQDKERLAALG
Position: 601-616
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: QDKERLAALGPEGAHG
Position: 607-622
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: AALGPEGAHGDTTFEY
Position: 613-628
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: GAHGDTTFEYQDLCRQ
Position: 619-634
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: TFEYQDLCRQHMATKS
Position: 625-640
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: LCRQHMATKSLFNRAE
Position: 631-646
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: ATKSLFNRAEGPPEPS
Position: 637-652
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: NRAEGPPEPSRVSSVS
Position: 643-658
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: PEPSRVSSVSSQFSDA
Position: 649-664
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: SSVSSQFSDAAQASPS
Position: 655-670
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: FSDAAQASPSSHSSTP
Position: 661-676
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: ASPSSHSSTPSWCEEP
Position: 667-682
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: SSTPSWCEEPAQANMD
Position: 673-688
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: CEEPAQANMDISTGHM
Position: 679-694
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: TGHMILAYMEDHLRNR
Position: 691-706
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: AYMEDHLRNRDRLAKE
Position: 697-712
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: LRNRDRLAKEWQALCA
Position: 703-718
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: LAKEWQALCAYQAEPN
Position: 709-724
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: ALCAYQAEPNTCATAQ
Position: 715-730
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: ATAQGEGNIKKNRHPD
Position: 727-742
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: GNIKKNRHPDFLPYDH
Position: 733-748
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: RHPDFLPYDHARIKLK
Position: 739-754
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: IKLKVESSPSRSDYIN
Position: 751-766
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: SSPSRSDYINASPIIE
Position: 757-772
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: PIIEHDPRMPAYIATQ
Position: 769-784
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: PRMPAYIATQGPLSHT
Position: 775-790
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: VKQCDRYWPDEGASLY
Position: 817-832
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: YWPDEGASLYHVYEVN
Position: 823-838
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: ASLYHVYEVNLVSEHI
Position: 829-844
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: YEVNLVSEHIWCEDFL
Position: 835-850
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: SFYLKNVQTQETRTLT
Position: 853-868
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: VQTQETRTLTQFHFLS
Position: 859-874
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: HFLSWPAEGTPASTRP
Position: 871-886
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: AEGTPASTRPLLDFRR
Position: 877-892
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: STRPLLDFRRKVNKCY
Position: 883-898
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: NKCYRGRSCPIIVHCS
Position: 895-910
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: VHCSDGAGRTGTYILI
Position: 907-922
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: AGRTGTYILIDMVLNR
Position: 913-928
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: VLNRMAKGVKEIDIAA
Position: 925-940
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: KGVKEIDIAATLEHVR
Position: 931-946
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: DIAATLEHVRDQRPGL
Position: 937-952
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: EHVRDQRPGLVRSKDQ
Position: 943-958
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: RPGLVRSKDQFEFALT
Position: 949-964
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: SKDQFEFALTAVAEEV
Position: 955-970
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: FALTAVAEEVNAILKA
Position: 961-976
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Chemical type: Peptide from protein
Sequence: AEEVNAILKALPQ
Position: 967-979
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  mean: 28.5 =/- 15 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo