Reference: Tobias Boettler; Philippe P Pagni; Rachel Jaffe; Yang Cheng; Peter Zerhouni; Matthias von Herrath. "The clinical and immunological significance of GAD-specific autoantibody and T-cell responses in type 1 diabetes." Journal of autoimmunity (2013).

Epitope: GAD P1
Chemical type: Peptide from protein
Sequence: MASPGSGFWSFGSEDGSGDS
Position: 1-20
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P1
Chemical type: Peptide from protein
Sequence: MASPGSGFWSFGSEDGSGDS
Position: 1-20
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P2
Chemical type: Peptide from protein
Sequence: FGSEDGSGDSENPGTARAWC
Position: 11-30
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P2
Chemical type: Peptide from protein
Sequence: FGSEDGSGDSENPGTARAWC
Position: 11-30
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P3
Chemical type: Peptide from protein
Sequence: ENPGTARAWCQVAQKFTGGI
Position: 21-40
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P3
Chemical type: Peptide from protein
Sequence: ENPGTARAWCQVAQKFTGGI
Position: 21-40
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P4
Chemical type: Peptide from protein
Sequence: QVAQKFTGGIGNKLCALLYG
Position: 31-50
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P4
Chemical type: Peptide from protein
Sequence: QVAQKFTGGIGNKLCALLYG
Position: 31-50
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P5
Chemical type: Peptide from protein
Sequence: GNKLCALLYGDAEKPAESGG
Position: 41-60
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P5
Chemical type: Peptide from protein
Sequence: GNKLCALLYGDAEKPAESGG
Position: 41-60
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P7
Chemical type: Peptide from protein
Sequence: SQPPRAAARKAACACDQKPC
Position: 61-80
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P7
Chemical type: Peptide from protein
Sequence: SQPPRAAARKAACACDQKPC
Position: 61-80
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P8
Chemical type: Peptide from protein
Sequence: AACACDQKPCSCSKVDVNYA
Position: 71-90
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P8
Chemical type: Peptide from protein
Sequence: AACACDQKPCSCSKVDVNYA
Position: 71-90
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P9
Chemical type: Peptide from protein
Sequence: SCSKVDVNYAFLHATDLLPA
Position: 81-100
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P9
Chemical type: Peptide from protein
Sequence: SCSKVDVNYAFLHATDLLPA
Position: 81-100
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P10
Chemical type: Peptide from protein
Sequence: FLHATDLLPACDGERPTLAF
Position: 91-110
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P10
Chemical type: Peptide from protein
Sequence: FLHATDLLPACDGERPTLAF
Position: 91-110
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P11
Chemical type: Peptide from protein
Sequence: CDGERPTLAFLQDVMNILLQ
Position: 101-120
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P11
Chemical type: Peptide from protein
Sequence: CDGERPTLAFLQDVMNILLQ
Position: 101-120
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P12
Chemical type: Peptide from protein
Sequence: LQDVMNILLQYVVKSFDRST
Position: 111-130
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P12
Chemical type: Peptide from protein
Sequence: LQDVMNILLQYVVKSFDRST
Position: 111-130
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P13
Chemical type: Peptide from protein
Sequence: YVVKSFDRSTKVIDFHYPNE
Position: 121-140
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P13
Chemical type: Peptide from protein
Sequence: YVVKSFDRSTKVIDFHYPNE
Position: 121-140
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P14
Chemical type: Peptide from protein
Sequence: KVIDFHYPNELLQEYNWELA
Position: 131-150
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P14
Chemical type: Peptide from protein
Sequence: KVIDFHYPNELLQEYNWELA
Position: 131-150
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P16
Chemical type: Peptide from protein
Sequence: DQPQNLEEILMHCQTTLKYA
Position: 151-170
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P16
Chemical type: Peptide from protein
Sequence: DQPQNLEEILMHCQTTLKYA
Position: 151-170
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P17
Chemical type: Peptide from protein
Sequence: MHCQTTLKYAIKTGHPRYFN
Position: 161-180
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P17
Chemical type: Peptide from protein
Sequence: MHCQTTLKYAIKTGHPRYFN
Position: 161-180
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P18
Chemical type: Peptide from protein
Sequence: IKTGHPRYFNQLSTGLDMVG
Position: 171-190
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P18
Chemical type: Peptide from protein
Sequence: IKTGHPRYFNQLSTGLDMVG
Position: 171-190
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P19
Chemical type: Peptide from protein
Sequence: QLSTGLDMVGLAADWLTSTA
Position: 181-200
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P19
Chemical type: Peptide from protein
Sequence: QLSTGLDMVGLAADWLTSTA
Position: 181-200
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P20
Chemical type: Peptide from protein
Sequence: LAADWLTSTANTNMFTYEIA
Position: 191-210
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P20
Chemical type: Peptide from protein
Sequence: LAADWLTSTANTNMFTYEIA
Position: 191-210
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P21
Chemical type: Peptide from protein
Sequence: NTNMFTYEIAPVFVLLEYVT
Position: 201-220
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P21
Chemical type: Peptide from protein
Sequence: NTNMFTYEIAPVFVLLEYVT
Position: 201-220
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P22
Chemical type: Peptide from protein
Sequence: PVFVLLEYVTLKKMREIIGW
Position: 211-230
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P22
Chemical type: Peptide from protein
Sequence: PVFVLLEYVTLKKMREIIGW
Position: 211-230
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P23
Chemical type: Peptide from protein
Sequence: LKKMREIIGWPGGSGDGIFS
Position: 221-240
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P23
Chemical type: Peptide from protein
Sequence: LKKMREIIGWPGGSGDGIFS
Position: 221-240
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P24
Chemical type: Peptide from protein
Sequence: PGGSGDGIFSPGGAISNMYA
Position: 231-250
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P24
Chemical type: Peptide from protein
Sequence: PGGSGDGIFSPGGAISNMYA
Position: 231-250
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P25
Chemical type: Peptide from protein
Sequence: PGGAISNMYAMMIARFKMFP
Position: 241-260
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P25
Chemical type: Peptide from protein
Sequence: PGGAISNMYAMMIARFKMFP
Position: 241-260
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P27
Chemical type: Peptide from protein
Sequence: EVKEKGMAALPRLIAFTSEH
Position: 261-280
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P27
Chemical type: Peptide from protein
Sequence: EVKEKGMAALPRLIAFTSEH
Position: 261-280
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P28
Chemical type: Peptide from protein
Sequence: PRLIAFTSEHSHFSLKKGAA
Position: 271-290
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P28
Chemical type: Peptide from protein
Sequence: PRLIAFTSEHSHFSLKKGAA
Position: 271-290
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P29
Chemical type: Peptide from protein
Sequence: SHFSLKKGAAALGIGTDSVI
Position: 281-300
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P29
Chemical type: Peptide from protein
Sequence: SHFSLKKGAAALGIGTDSVI
Position: 281-300
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P30
Chemical type: Peptide from protein
Sequence: ALGIGTDSVILIKCDERGKM
Position: 291-310
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P30
Chemical type: Peptide from protein
Sequence: ALGIGTDSVILIKCDERGKM
Position: 291-310
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P31
Chemical type: Peptide from protein
Sequence: LIKCDERGKMIPSDLERRIL
Position: 301-320
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P31
Chemical type: Peptide from protein
Sequence: LIKCDERGKMIPSDLERRIL
Position: 301-320
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P32
Chemical type: Peptide from protein
Sequence: IPSDLERRILEAKQKGFVPF
Position: 311-330
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P32
Chemical type: Peptide from protein
Sequence: IPSDLERRILEAKQKGFVPF
Position: 311-330
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P48
Chemical type: Peptide from protein
Sequence: VDKCLELAEYLYNIIKNREG
Position: 471-490
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P49
Chemical type: Peptide from protein
Sequence: LYNIIKNREGYEMVFDGKPQ
Position: 481-500
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P50
Chemical type: Peptide from protein
Sequence: YEMVFDGKPQHTNVCFWYIP
Position: 491-510
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P51
Chemical type: Peptide from protein
Sequence: HTNVCFWYIPPSLRTLEDNE
Position: 501-520
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P52
Chemical type: Peptide from protein
Sequence: PSLRTLEDNEERMSRLSKVA
Position: 511-530
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P53
Chemical type: Peptide from protein
Sequence: ERMSRLSKVAPVIKARMMEY
Position: 521-540
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P53
Chemical type: Peptide from protein
Sequence: ERMSRLSKVAPVIKARMMEY
Position: 521-540
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P55
Chemical type: Peptide from protein
Sequence: GTTMVSYQPLGDKVNFFRMV
Position: 541-560
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P55
Chemical type: Peptide from protein
Sequence: GTTMVSYQPLGDKVNFFRMV
Position: 541-560
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P56
Chemical type: Peptide from protein
Sequence: GDKVNFFRMVISNPAATHQD
Position: 551-570
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P56
Chemical type: Peptide from protein
Sequence: GDKVNFFRMVISNPAATHQD
Position: 551-570
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P58
Chemical type: Peptide from protein
Sequence: IDFLIEEIERLGQDL
Position: 571-585
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD P58
Chemical type: Peptide from protein
Sequence: IDFLIEEIERLGQDL
Position: 571-585
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Gp (33-41)
Chemical type: Peptide from protein
Sequence: KAVYNFATC
Position: 33-41
Source molecule (GenBank): ABC96001.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Gp (33-41)
Chemical type: Peptide from protein
Sequence: KAVYNFATC
Position: 33-41
Source molecule (GenBank): ABC96001.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Gp (33-41)
Chemical type: Peptide from protein
Sequence: KAVYNFATC
Position: 33-41
Source molecule (GenBank): ABC96001.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Gp (33-41)
Chemical type: Peptide from protein
Sequence: KAVYNFATC
Position: 33-41
Source molecule (GenBank): ABC96001.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo