Reference: Sandeep Kumar Dhanda; Alba Grifoni; John Pham; Kerrie Vaughan; John Sidney; Bjoern Peters; Alessandro Sette. "Development of a strategy and computational application to select candidate protein analogues with reduced HLA binding and immunogenicity." Immunology (2018).

Epitope: V299M
Chemical type: Peptide, no natural source
Sequence: GATALVLQMLNVPRL
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: V299M
Chemical type: Peptide, no natural source
Sequence: GATALVLQMLNVPRL
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P303A
Chemical type: Peptide, no natural source
Sequence: GATALVLQVLNVARL
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P303A
Chemical type: Peptide, no natural source
Sequence: GATALVLQVLNVARL
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A294F
Chemical type: Peptide, no natural source
Sequence: GATFLVLQVLNVPRL
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A294F
Chemical type: Peptide, no natural source
Sequence: GATFLVLQVLNVPRL
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A294Y
Chemical type: Peptide, no natural source
Sequence: GATYLVLQVLNVPRL
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A294Y
Chemical type: Peptide, no natural source
Sequence: GATYLVLQVLNVPRL
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: V299Y
Chemical type: Peptide, no natural source
Sequence: VLQYLNVPRLMTQDC
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: V299Y
Chemical type: Peptide, no natural source
Sequence: VLQYLNVPRLMTQDC
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Q298F
Chemical type: Peptide, no natural source
Sequence: VLFVLNVPRLMTQDC
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Q298F
Chemical type: Peptide, no natural source
Sequence: VLFVLNVPRLMTQDC
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Q298Y
Chemical type: Peptide, no natural source
Sequence: VLYVLNVPRLMTQDC
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Q298Y
Chemical type: Peptide, no natural source
Sequence: VLYVLNVPRLMTQDC
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: V302A
Chemical type: Peptide, no natural source
Sequence: VLQVLNAPRLMTQDC
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: V302A
Chemical type: Peptide, no natural source
Sequence: VLQVLNAPRLMTQDC
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L297P
Chemical type: Peptide, no natural source
Sequence: GATALVPQVLNVPRL
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L297P
Chemical type: Peptide, no natural source
Sequence: GATALVPQVLNVPRL
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L300G
Chemical type: Peptide, no natural source
Sequence: GATALVLQVGNVPRL
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L300G
Chemical type: Peptide, no natural source
Sequence: GATALVLQVGNVPRL
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L300R
Chemical type: Peptide, no natural source
Sequence: GATALVLQVRNVPRL
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L300R
Chemical type: Peptide, no natural source
Sequence: GATALVLQVRNVPRL
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: R304G
Chemical type: Peptide, no natural source
Sequence: GATALVLQVLNVPGL
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: R304G
Chemical type: Peptide, no natural source
Sequence: GATALVLQVLNVPGL
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L305E
Chemical type: Peptide, no natural source
Sequence: GATALVLQVLNVPRE
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L305E
Chemical type: Peptide, no natural source
Sequence: GATALVLQVLNVPRE
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L305D
Chemical type: Peptide, no natural source
Sequence: GATALVLQVLNVPRD
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L305D
Chemical type: Peptide, no natural source
Sequence: GATALVLQVLNVPRD
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L297P
Chemical type: Peptide, no natural source
Sequence: VPQVLNVPRLMTQDC
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L297P
Chemical type: Peptide, no natural source
Sequence: VPQVLNVPRLMTQDC
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L297G
Chemical type: Peptide, no natural source
Sequence: VGQVLNVPRLMTQDC
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L297G
Chemical type: Peptide, no natural source
Sequence: VGQVLNVPRLMTQDC
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L300G
Chemical type: Peptide, no natural source
Sequence: VLQVGNVPRLMTQDC
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L300G
Chemical type: Peptide, no natural source
Sequence: VLQVGNVPRLMTQDC
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L300R
Chemical type: Peptide, no natural source
Sequence: VLQVRNVPRLMTQDC
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L300R
Chemical type: Peptide, no natural source
Sequence: VLQVRNVPRLMTQDC
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: R304G
Chemical type: Peptide, no natural source
Sequence: VLQVLNVPGLMTQDC
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: R304G
Chemical type: Peptide, no natural source
Sequence: VLQVLNVPGLMTQDC
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L305E
Chemical type: Peptide, no natural source
Sequence: VLQVLNVPREMTQDC
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L305E
Chemical type: Peptide, no natural source
Sequence: VLQVLNVPREMTQDC
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L297P
Chemical type: Peptide, no natural source
Sequence: QLLDRGATALVPQVL
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L297P
Chemical type: Peptide, no natural source
Sequence: QLLDRGATALVPQVL
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L297G
Chemical type: Peptide, no natural source
Sequence: QLLDRGATALVGQVL
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L297G
Chemical type: Peptide, no natural source
Sequence: QLLDRGATALVGQVL
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L300G
Chemical type: Peptide, no natural source
Sequence: QLLDRGATALVLQVG
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L300G
Chemical type: Peptide, no natural source
Sequence: QLLDRGATALVLQVG
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L300R
Chemical type: Peptide, no natural source
Sequence: QLLDRGATALVLQVR
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L300R
Chemical type: Peptide, no natural source
Sequence: QLLDRGATALVLQVR
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L305E
Chemical type: Peptide, no natural source
Sequence: NVPREMTQDCLQQSR
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L305E
Chemical type: Peptide, no natural source
Sequence: NVPREMTQDCLQQSR
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L305D
Chemical type: Peptide, no natural source
Sequence: NVPRDMTQDCLQQSR
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: L305D
Chemical type: Peptide, no natural source
Sequence: NVPRDMTQDCLQQSR
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated