Reference: Tamar Ratishvili; Huy Quang Quach; Iana H Haralambieva; Yogesh R Suryawanshi; Inna G Ovsyannikova; Richard B Kennedy; Gregory A Poland. "A multifaceted approach for identification, validation, and immunogenicity of naturally processed and in silico-predicted highly conserved SARS-CoV-2 peptides." Vaccine (2024).

Epitope: M1
Chemical type: Peptide from protein
Sequence: WLLWPVTLA
Position: 55-63
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M2
Chemical type: Peptide from protein
Sequence: LLWPVTLACF
Position: 56-65
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M3
Chemical type: Peptide from protein
Sequence: TLACFVLAA
Position: 61-69
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M6
Chemical type: Peptide from protein
Sequence: SMWSFNPET
Position: 108-116
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N7
Chemical type: Peptide from protein
Sequence: MEVTPSGTWL
Position: 322-331
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N8
Chemical type: Peptide from protein
Sequence: VTPSGTWLTY
Position: 324-333
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N11
Chemical type: Peptide from protein
Sequence: WLTYTGAIKL
Position: 330-339
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N12
Chemical type: Peptide from protein
Sequence: PNFKDQVILL
Position: 344-353
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N14
Chemical type: Peptide from protein
Sequence: LLNKHIDAY
Position: 352-360
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Orf9b-2
Chemical type: Peptide from protein
Sequence: LVDPQIQL
Position: 14-21
Source molecule (GenBank): P0DTD2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Orf9b-3
Chemical type: Peptide from protein
Sequence: KLATTEELPDE
Position: 80-90
Source molecule (GenBank): P0DTD2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Orf9b-4
Chemical type: Peptide from protein
Sequence: TEELPDEF
Position: 84-91
Source molecule (GenBank): P0DTD2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S3
Chemical type: Peptide from protein
Sequence: YSSANNCTF
Position: 160-168
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S9
Chemical type: Peptide from protein
Sequence: KLNDLCFTNV
Position: 386-395
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S14
Chemical type: Peptide from protein
Sequence: FIEDLLFNKV
Position: 817-826
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S17
Chemical type: Peptide from protein
Sequence: VLNDILSRL
Position: 976-984
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S18
Chemical type: Peptide from protein
Sequence: VVFLHVTYV
Position: 1060-1068
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S19
Chemical type: Peptide from protein
Sequence: FIAGLIAIV
Position: 1220-1228
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M4
Chemical type: Peptide from protein
Sequence: YRINWITGGIAIAMA
Position: 71-85
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M7
Chemical type: Peptide from protein
Sequence: ESELVIGAVILRGHL
Position: 135-149
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M8
Chemical type: Peptide from protein
Sequence: GAVILRGHLRIAGHHLGR
Position: 141-158
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M9
Chemical type: Peptide from protein
Sequence: EITVATSRTLSYYKL
Position: 167-181
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M10
Chemical type: Peptide from protein
Sequence: TSRTLSYYKLGASQRVA
Position: 172-188
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M12
Chemical type: Peptide from protein
Sequence: SQRVAGDSGFAAYSR
Position: 184-198
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N1
Chemical type: Peptide from protein
Sequence: LSPRWYFYYLGTGPEAGL
Position: 104-121
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N2
Chemical type: Peptide from protein
Sequence: LGTGPEAGLPYGANKDGIIWVA
Position: 113-134
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N4
Chemical type: Peptide from protein
Sequence: DQELIRQGTDYKHWPQIAQFAPS
Position: 288-310
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N5
Chemical type: Peptide from protein
Sequence: IRQGTDYKHWPQIAQFAPSASAFFG
Position: 292-316
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N6
Chemical type: Peptide from protein
Sequence: SRIGMEVTPSGTWLT
Position: 318-332
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N9
Chemical type: Peptide from protein
Sequence: VTPSGTWLTYTGAIK
Position: 324-338
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N10
Chemical type: Peptide from protein
Sequence: VTPSGTWLTYTGAIKLDDKDPNFK
Position: 324-347
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N13
Chemical type: Peptide from protein
Sequence: DQVILLNKHIDAYK
Position: 348-361
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Orf3a-1
Chemical type: Peptide from protein
Sequence: YFTSDYYQLYSTQLSTDTGV
Position: 206-225
Source molecule (GenBank): P0DTC3.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Orf7b-1
Chemical type: Peptide from protein
Sequence: VKHVYQLRARSVSPK
Position: 71-85
Source molecule (GenBank): P0DTC7.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Orf9b-1
Chemical type: Peptide from protein
Sequence: PKISEMHPALRLVD
Position: 3-16
Source molecule (GenBank): P0DTD2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Orf9b-5
Chemical type: Peptide from protein
Sequence: NAVGRDQNNVGPKVYPIIL
Position: 28-46
Source molecule (GenBank): P0DTD2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Orf9b-6
Chemical type: Peptide from protein
Sequence: PQIQLAVTRMENAVGRD
Position: 17-33
Source molecule (GenBank): P0DTD2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S1
Chemical type: Peptide from protein
Sequence: PFFSNVTWFHAIHVS
Position: 57-71
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S2
Chemical type: Peptide from protein
Sequence: SNVTWFHAIHVSGTN
Position: 60-74
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S4
Chemical type: Peptide from protein
Sequence: NCTFEYVSQPFLMDL
Position: 165-179
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S5
Chemical type: Peptide from protein
Sequence: CTFEYVSQPFLMDLE
Position: 166-180
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S6
Chemical type: Peptide from protein
Sequence: NITRFQTLLALHRSY
Position: 234-248
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S7
Chemical type: Peptide from protein
Sequence: RFASVYAWNRKRISN
Position: 346-360
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S8
Chemical type: Peptide from protein
Sequence: ASVYAWNRKRISNCVA
Position: 348-363
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S10
Chemical type: Peptide from protein
Sequence: FNCYFPLQSYGFQPT
Position: 486-500
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S11
Chemical type: Peptide from protein
Sequence: QTQTNSPRRARSV
Position: 675-687
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S12
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNR
Position: 751-765
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S13
Chemical type: Peptide from protein
Sequence: RSFIEDLLFNKVTLA
Position: 815-829
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S15
Chemical type: Peptide from protein
Sequence: LTDEMIAQYTSALLA
Position: 865-879
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S16
Chemical type: Peptide from protein
Sequence: TDEMIAQYTSALLAG
Position: 866-880
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo