Reference: Dapeng Sun; Zhe Sang; Yong Joon Kim; Yufei Xiang; Tomer Cohen; Anna K Belford; Alexis Huet; James F Conway; Ji Sun; Derek J Taylor; Dina Schneidman-Duhovny; Cheng Zhang; Wei Huang; Yi Shi. "Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes." Nature communications (2021).

Epitope: Epitope of nanobody Nb21 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y449, N450, Y451, L452, I472, V483, E484, G485, F486, N487, Y489, F490, S494
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody Nb21 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y449, N450, Y451, L452, I472, V483, E484, G485, F486, N487, Y489, F490, S494
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.48
Host: M

Epitope: Epitope of nanobody Nb21 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y449, N450, Y451, L452, I472, V483, E484, G485, F486, N487, Y489, F490, S494
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody Nb21 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y449, N450, Y451, L452, I472, V483, E484, G485, F486, N487, Y489, F490, S494
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody Nb21 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y449, N450, Y451, L452, I472, V483, E484, G485, F486, N487, Y489, F490, S494
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody Nb21 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y449, N450, Y451, L452, I472, V483, E484, G485, F486, N487, Y489, F490, S494
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody Nb95 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, G404, D405, V407, R408, V503, G504
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 31.63
Host: M

Epitope: Epitope of nanobody Nb95 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, G404, D405, V407, R408, V503, G504
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody Nb95 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, G404, D405, V407, R408, V503, G504
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody Nb95 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, G404, D405, V407, R408, V503, G504
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 6.05
Host: M

Epitope: Epitope of nanobody Nb17 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: F347, A348, S349, Y351, N354, R355, Y449, N450, L452, R466, I468, T470, N481, G482, V483, E484, F490, L492, Q493, S494
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody Nb17 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: F347, A348, S349, Y351, N354, R355, Y449, N450, L452, R466, I468, T470, N481, G482, V483, E484, F490, L492, Q493, S494
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody Nb17 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: F347, A348, S349, Y351, N354, R355, Y449, N450, L452, R466, I468, T470, N481, G482, V483, E484, F490, L492, Q493, S494
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.69
Host: M

Epitope: Epitope of nanobody Nb17 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: F347, A348, S349, Y351, N354, R355, Y449, N450, L452, R466, I468, T470, N481, G482, V483, E484, F490, L492, Q493, S494
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody Nb36 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, A352, N354, R355, K356, E465, R466, D467, I468
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.7
Host: M

Epitope: Epitope of nanobody Nb36 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, A352, N354, R355, K356, E465, R466, D467, I468
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody Nb36 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, A352, N354, R355, K356, E465, R466, D467, I468
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: M