Reference: Qin Hong; Wenyu Han; Jiawei Li; Shiqi Xu; Yifan Wang; Cong Xu; Zuyang Li; Yanxing Wang; Chao Zhang; Zhong Huang; Yao Cong. "Molecular basis of receptor binding and antibody neutralization of Omicron." Nature (2022).

Epitope: Epitope of mAb 8D3
Chemical type: Discontinuous protein residues
Discontinuous residues: F454, Y471, Q472, A473, G474, S475, K476, P477, G483, F484, N485, Y487
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive-Low
Host: F 6-8 weeks

Epitope: Epitope of mAb 8D3
Chemical type: Discontinuous protein residues
Discontinuous residues: F454, Y471, Q472, A473, G474, S475, K476, P477, G483, F484, N485, Y487
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb 8D3
Chemical type: Discontinuous protein residues
Discontinuous residues: F454, Y471, Q472, A473, G474, S475, K476, P477, G483, F484, N485, Y487
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb 8D3
Chemical type: Discontinuous protein residues
Discontinuous residues: F454, Y471, Q472, A473, G474, S475, K476, P477, G483, F484, N485, Y487
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb 8D3
Chemical type: Discontinuous protein residues
Discontinuous residues: F454, Y471, Q472, A473, G474, S475, K476, P477, G483, F484, N485, Y487
Source molecule (GenBank): UEO57867.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb S5D2
Chemical type: Discontinuous protein residues
Discontinuous residues: F453, S474, T475, P476, C477, N478, G482, F483, N484, Y486
Source molecule (GenBank): QWW93436.1
Assay category: BCell
Result: Positive-Low
Host: F 6-8 weeks

Epitope: Epitope of mAb S5D2
Chemical type: Discontinuous protein residues
Discontinuous residues: F453, S474, T475, P476, C477, N478, G482, F483, N484, Y486
Source molecule (GenBank): QWW93436.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb S5D2
Chemical type: Discontinuous protein residues
Discontinuous residues: F453, S474, T475, P476, C477, N478, G482, F483, N484, Y486
Source molecule (GenBank): QWW93436.1
Assay category: BCell
Result: Positive-Low
Host: F 6-8 weeks

Epitope: Epitope of mAb S5D2
Chemical type: Discontinuous protein residues
Discontinuous residues: F453, S474, T475, P476, C477, N478, G482, F483, N484, Y486
Source molecule (GenBank): QWW93436.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb S3H3 on Omicron S trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N532, L533, V534, K535, N536, K537, E554, S555, N556, T581, L582, E583, I584; B: T323, E324
Source molecule (GenBank): UJX89775.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb S3H3 on Omicron S trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N532, L533, V534, K535, N536, K537, E554, S555, N556, T581, L582, E583, I584; B: T323, E324
Source molecule (GenBank): UJX89775.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb S3H3 on Omicron S trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N532, L533, V534, K535, N536, K537, E554, S555, N556, T581, L582, E583, I584; B: T323, E324
Source molecule (GenBank): UJX89775.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb S3H3 on Omicron S trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N532, L533, V534, K535, N536, K537, E554, S555, N556, T581, L582, E583, I584; B: T323, E324
Source molecule (GenBank): UJX89775.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb S3H3 on Omicron S trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N532, L533, V534, K535, N536, K537, E554, S555, N556, T581, L582, E583, I584; B: T323, E324
Source molecule (GenBank): UJX89775.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb S3H3 on Omicron S trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N532, L533, V534, K535, N536, K537, E554, S555, N556, T581, L582, E583, I584; B: T323, E324
Source molecule (GenBank): UJX89775.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb S3H3 on Omicron S trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N532, L533, V534, K535, N536, K537, E554, S555, N556, T581, L582, E583, I584; B: T323, E324
Source molecule (GenBank): UJX89775.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb S3H3 on Omicron S trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N532, L533, V534, K535, N536, K537, E554, S555, N556, T581, L582, E583, I584; B: T323, E324
Source molecule (GenBank): UJX89775.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of mAb S3H3 on Omicron S trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N532, L533, V534, K535, N536, K537, E554, S555, N556, T581, L582, E583, I584; B: T323, E324
Source molecule (GenBank): UJX89775.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks