Reference: Yoh Matsumoto; Il-Kwon Park; Keiko Hiraki; Shin Ohtani; Kuniko Kohyama. "Role of pathogenic T cells and autoantibodies in relapse and progression of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis in LEW.1AV1 rats." Immunology (2009).

Epitope: P1
Chemical type: Peptide from protein
Sequence: GQFRVIGPGHPIRALVGDEAELP
Position: 1-23
Source molecule (GenBank): AAF74786.1
Assay category: BCell
Result: Positive
Host:  8-12 weeks

Epitope: P1
Chemical type: Peptide from protein
Sequence: GQFRVIGPGHPIRALVGDEAELP
Position: 1-23
Source molecule (GenBank): AAF74786.1
Assay category: BCell
Result: Positive-Low
Host:  8-12 weeks

Epitope: P1
Chemical type: Peptide from protein
Sequence: GQFRVIGPGHPIRALVGDEAELP
Position: 1-23
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: P1
Chemical type: Peptide from protein
Sequence: GQFRVIGPGHPIRALVGDEAELP
Position: 1-23
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks

Epitope: P2
Chemical type: Peptide from protein
Sequence: DEAELPCRISPGKNATGMEVGWY
Position: 18-40
Source molecule (GenBank): AAF74786.1
Assay category: BCell
Result: Negative
Host:  8-12 weeks

Epitope: P2
Chemical type: Peptide from protein
Sequence: DEAELPCRISPGKNATGMEVGWY
Position: 18-40
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: P2
Chemical type: Peptide from protein
Sequence: DEAELPCRISPGKNATGMEVGWY
Position: 18-40
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks

Epitope: P3
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 35-55
Source molecule (GenBank): AAF74786.1
Assay category: BCell
Result: Negative
Host:  8-12 weeks

Epitope: P3
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 35-55
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: P3
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 35-55
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks

Epitope: P4
Chemical type: Peptide from protein
Sequence: LYRNGKDQDAEQAPEYRGRTE
Position: 50-70
Source molecule (GenBank): AAF74786.1
Assay category: BCell
Result: Negative
Host:  8-12 weeks

Epitope: P4
Chemical type: Peptide from protein
Sequence: LYRNGKDQDAEQAPEYRGRTE
Position: 50-70
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: P4
Chemical type: Peptide from protein
Sequence: LYRNGKDQDAEQAPEYRGRTE
Position: 50-70
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks

Epitope: P5
Chemical type: Peptide from protein
Sequence: YRGRTELLKESIGEGKVALR
Position: 65-84
Source molecule (GenBank): AAF74786.1
Assay category: BCell
Result: Negative
Host:  8-12 weeks

Epitope: P5
Chemical type: Peptide from protein
Sequence: YRGRTELLKESIGEGKVALR
Position: 65-84
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: P5
Chemical type: Peptide from protein
Sequence: YRGRTELLKESIGEGKVALR
Position: 65-84
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks

Epitope: P6
Chemical type: Peptide from protein
Sequence: GKVALRIQNVRFSDEGGY
Position: 79-96
Source molecule (GenBank): AAF74786.1
Assay category: BCell
Result: Negative
Host:  8-12 weeks

Epitope: P6
Chemical type: Peptide from protein
Sequence: GKVALRIQNVRFSDEGGY
Position: 79-96
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: P6
Chemical type: Peptide from protein
Sequence: GKVALRIQNVRFSDEGGY
Position: 79-96
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks

Epitope: P7
Chemical type: Peptide from protein
Sequence: SDEGGYTCFFRDHSYQEE
Position: 91-108
Source molecule (GenBank): AAF74786.1
Assay category: BCell
Result: Negative
Host:  8-12 weeks

Epitope: P7
Chemical type: Peptide from protein
Sequence: SDEGGYTCFFRDHSYQEE
Position: 91-108
Source molecule (GenBank): AAF74786.1
Assay category: BCell
Result: Positive
Host:  8-12 weeks

Epitope: P7
Chemical type: Peptide from protein
Sequence: SDEGGYTCFFRDHSYQEE
Position: 91-108
Source molecule (GenBank): AAF74786.1
Assay category: BCell
Result: Negative
Host:  8-12 weeks

Epitope: P7
Chemical type: Peptide from protein
Sequence: SDEGGYTCFFRDHSYQEE
Position: 91-108
Source molecule (GenBank): AAF74786.1
Assay category: BCell
Result: Positive
Host:  8-12 weeks

Epitope: P7
Chemical type: Peptide from protein
Sequence: SDEGGYTCFFRDHSYQEE
Position: 91-108
Source molecule (GenBank): AAF74786.1
Assay category: BCell
Result: Negative
Host:  8-12 weeks

Epitope: P7
Chemical type: Peptide from protein
Sequence: SDEGGYTCFFRDHSYQEE
Position: 91-108
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: P7
Chemical type: Peptide from protein
Sequence: SDEGGYTCFFRDHSYQEE
Position: 91-108
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: P7
Chemical type: Peptide from protein
Sequence: SDEGGYTCFFRDHSYQEE
Position: 91-108
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: P7
Chemical type: Peptide from protein
Sequence: SDEGGYTCFFRDHSYQEE
Position: 91-108
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: P8
Chemical type: Peptide from protein
Sequence: HSYQEEAAVELKVEDPFYWINPG
Position: 103-125
Source molecule (GenBank): AAF74786.1
Assay category: BCell
Result: Negative
Host:  8-12 weeks

Epitope: P8
Chemical type: Peptide from protein
Sequence: HSYQEEAAVELKVEDPFYWINPG
Position: 103-125
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: P8
Chemical type: Peptide from protein
Sequence: HSYQEEAAVELKVEDPFYWINPG
Position: 103-125
Source molecule (GenBank): AAF74786.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks