Reference: Frederic Morvan; Jean-Michel Rondeau; Chao Zou; Giulia Minetti; Clemens Scheufler; Meike Scharenberg; Carsten Jacobi; Pascale Brebbia; Veronique Ritter; Gauthier Toussaint; Claudia Koelbing; Xavier Leber; Alain Schilb; Florian Witte; Sylvie Lehmann; Elke Koch; Sabine Geisse; David J Glass; Estelle Lach-Trifilieff. "Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy." Proceedings of the National Academy of Sciences of the United States of America (2017).

Epitope: Epitope of bimagrumab (BXM338) on ActRIIA
Chemical type: Discontinuous protein residues
Discontinuous residues: K39, D40, D55, F61, T63, V74, K75, C78, W79, L80, D81, D82, I83, N84, Y86, V100, F102
Source molecule (GenBank): P27037.1
Assay category: BCell
Result: Positive

Epitope: Epitope of bimagrumab (BXM338) on ActRIIA
Chemical type: Discontinuous protein residues
Discontinuous residues: K39, D40, D55, F61, T63, V74, K75, C78, W79, L80, D81, D82, I83, N84, Y86, V100, F102
Source molecule (GenBank): P27037.1
Assay category: BCell
Result: Positive

Epitope: Epitope of bimagrumab (BXM338) on ActRIIA
Chemical type: Discontinuous protein residues
Discontinuous residues: K39, D40, D55, F61, T63, V74, K75, C78, W79, L80, D81, D82, I83, N84, Y86, V100, F102
Source molecule (GenBank): P27037.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.35

Epitope: Epitope of bimagrumab (BXM338) on ActRIIA
Chemical type: Discontinuous protein residues
Discontinuous residues: K39, D40, D55, F61, T63, V74, K75, C78, W79, L80, D81, D82, I83, N84, Y86, V100, F102
Source molecule (GenBank): P27037.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.973

Epitope: Epitope of bimagrumab (BXM338) on ActRIIA
Chemical type: Discontinuous protein residues
Discontinuous residues: K39, D40, D55, F61, T63, V74, K75, C78, W79, L80, D81, D82, I83, N84, Y86, V100, F102
Source molecule (GenBank): P27037.1
Assay category: BCell
Result: Positive

Epitope: Epitope of bimagrumab (BXM338) on ActRIIB
Chemical type: Discontinuous protein residues
Discontinuous residues: N35, L38, E39, E52, D54, K55, Y60, S62, K74, C77, W78, L79, D80, D81, F82, N83, Y85, E94, V99, F101
Source molecule (GenBank): Q13705.3
Assay category: BCell
Result: Positive
Quantitative measurement: 3.35

Epitope: Epitope of bimagrumab (BXM338) on ActRIIB
Chemical type: Discontinuous protein residues
Discontinuous residues: N35, L38, E39, E52, D54, K55, Y60, S62, K74, C77, W78, L79, D80, D81, F82, N83, Y85, E94, V99, F101
Source molecule (GenBank): Q13705.3
Assay category: BCell
Result: Positive

Epitope: Epitope of bimagrumab (BXM338) on ActRIIB
Chemical type: Discontinuous protein residues
Discontinuous residues: N35, L38, E39, E52, D54, K55, Y60, S62, K74, C77, W78, L79, D80, D81, F82, N83, Y85, E94, V99, F101
Source molecule (GenBank): Q13705.3
Assay category: BCell
Result: Positive

Epitope: Epitope of bimagrumab (BXM338) on ActRIIB
Chemical type: Discontinuous protein residues
Discontinuous residues: N35, L38, E39, E52, D54, K55, Y60, S62, K74, C77, W78, L79, D80, D81, F82, N83, Y85, E94, V99, F101
Source molecule (GenBank): Q13705.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.016

Epitope: Epitope of bimagrumab (BXM338) on ActRIIB
Chemical type: Discontinuous protein residues
Discontinuous residues: N35, L38, E39, E52, D54, K55, Y60, S62, K74, C77, W78, L79, D80, D81, F82, N83, Y85, E94, V99, F101
Source molecule (GenBank): Q13705.3
Assay category: BCell
Result: Positive
Quantitative measurement: 2.0

Epitope: Epitope of bimagrumab (BXM338) on ActRIIB
Chemical type: Discontinuous protein residues
Discontinuous residues: N35, L38, E39, E52, D54, K55, Y60, S62, K74, C77, W78, L79, D80, D81, F82, N83, Y85, E94, V99, F101
Source molecule (GenBank): Q13705.3
Assay category: BCell
Result: Positive