Reference: Wenhai Liu; Masanori Onda; Byungkook Lee; Robert J Kreitman; Raffit Hassan; Laiman Xiang; Ira Pastan. "Recombinant immunotoxin engineered for low immunogenicity and antigenicity by identifying and silencing human B-cell epitopes." Proceedings of the National Academy of Sciences of the United States of America (2012).

Epitope: H1
Chemical type: Discontinuous protein residues
Discontinuous residues: D428, E445, R452
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive

Epitope: H1 variation 2
Chemical type: Discontinuous protein residues
Discontinuous residues: D428, R452, E456
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive

Epitope: H2
Chemical type: Discontinuous protein residues
Discontinuous residues: R492, R576
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive

Epitope: H2 variation 1
Chemical type: Discontinuous protein residues
Discontinuous residues: R492, E573, R576
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive

Epitope: H2 variation 2
Chemical type: Discontinuous protein residues
Discontinuous residues: R492, Y506, D606
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive

Epitope: H2 variation 3
Chemical type: Discontinuous protein residues
Discontinuous residues: D488, R492, Y506, E547
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive

Epitope: H2 variation 4
Chemical type: Discontinuous protein residues
Discontinuous residues: D488, R492, L541
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive

Epitope: H2 variation 6
Chemical type: Discontinuous protein residues
Discontinuous residues: D488, R492
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive

Epitope: H2 variation 7
Chemical type: Discontinuous protein residues
Discontinuous residues: D486, R492
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive

Epitope: H3
Chemical type: Discontinuous protein residues
Discontinuous residues: R483
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive

Epitope: H4
Chemical type: Discontinuous protein residues
Discontinuous residues: R530
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive

Epitope: H4 variation 1
Chemical type: Discontinuous protein residues
Discontinuous residues: R457, R530
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive

Epitope: H5
Chemical type: Discontinuous protein residues
Discontinuous residues: R515, R601
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive

Epitope: H5 variation 1
Chemical type: Discontinuous protein residues
Discontinuous residues: R515
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive

Epitope: H6
Chemical type: Discontinuous protein residues
Discontinuous residues: R563, R588
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive

Epitope: H6 variation 1
Chemical type: Discontinuous protein residues
Discontinuous residues: R588
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive

Epitope: HA22-LR-LO10
Chemical type: Discontinuous protein residues
Discontinuous residues: R452, R483, D488, R492, R515, R530, R563
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive-Low

Epitope: HA22-LR-8M
Chemical type: Discontinuous protein residues
Discontinuous residues: D431, R457,R492, R515, R538, E573, K615, Q617
Source molecule (GenBank): P11439.2
Assay category: BCell
Result: Positive-Intermediate