Reference: Xiaolin Wen; Naveenchandra Suryadevara; Nurgun Kose; Jing Liu; Xiaoyan Zhan; Laura S Handal; Lauren E Williamson; Andrew Trivette; Robert H Carnahan; Theodore S Jardetzky; James E Crowe. "Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode." Cell host & microbe (2023).

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Quantitative measurement: 56500.0
Host:  8 years

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000696
Host:  8 years

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.23
Host:  8 years

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on HMPV F monomer and dimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L36, T41, R156, N233, M234, P235, T236, S237, A238, Q240, L243, I275, G277, I279, D280, P282, Q312, N313, A314, E345
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on RSV F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N428, R429, G430; C: L45, Y53, M264, P265, I266, T267, N268, D269, Q270, L273, L305, G307, D310, T311, P312, D344, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000696
Host:  8 years

Epitope: Epitope of RSV-199 Fab on RSV F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N428, R429, G430; C: L45, Y53, M264, P265, I266, T267, N268, D269, Q270, L273, L305, G307, D310, T311, P312, D344, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on RSV F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N428, R429, G430; C: L45, Y53, M264, P265, I266, T267, N268, D269, Q270, L273, L305, G307, D310, T311, P312, D344, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.23
Host:  8 years

Epitope: Epitope of RSV-199 Fab on RSV F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N428, R429, G430; C: L45, Y53, M264, P265, I266, T267, N268, D269, Q270, L273, L305, G307, D310, T311, P312, D344, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Quantitative measurement: 56500.0
Host:  8 years

Epitope: Epitope of RSV-199 Fab on RSV F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N428, R429, G430; C: L45, Y53, M264, P265, I266, T267, N268, D269, Q270, L273, L305, G307, D310, T311, P312, D344, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on RSV F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N428, R429, G430; C: L45, Y53, M264, P265, I266, T267, N268, D269, Q270, L273, L305, G307, D310, T311, P312, D344, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on RSV F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N428, R429, G430; C: L45, Y53, M264, P265, I266, T267, N268, D269, Q270, L273, L305, G307, D310, T311, P312, D344, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on RSV F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N428, R429, G430; C: L45, Y53, M264, P265, I266, T267, N268, D269, Q270, L273, L305, G307, D310, T311, P312, D344, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on RSV F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N428, R429, G430; C: L45, Y53, M264, P265, I266, T267, N268, D269, Q270, L273, L305, G307, D310, T311, P312, D344, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on RSV F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N428, R429, G430; C: L45, Y53, M264, P265, I266, T267, N268, D269, Q270, L273, L305, G307, D310, T311, P312, D344, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on RSV F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N428, R429, G430; C: L45, Y53, M264, P265, I266, T267, N268, D269, Q270, L273, L305, G307, D310, T311, P312, D344, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on RSV F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N428, R429, G430; C: L45, Y53, M264, P265, I266, T267, N268, D269, Q270, L273, L305, G307, D310, T311, P312, D344, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on RSV F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N428, R429, G430; C: L45, Y53, M264, P265, I266, T267, N268, D269, Q270, L273, L305, G307, D310, T311, P312, D344, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on RSV F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N428, R429, G430; C: L45, Y53, M264, P265, I266, T267, N268, D269, Q270, L273, L305, G307, D310, T311, P312, D344, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on RSV F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N428, R429, G430; C: L45, Y53, M264, P265, I266, T267, N268, D269, Q270, L273, L305, G307, D310, T311, P312, D344, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of RSV-199 Fab on RSV F
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N428, R429, G430; C: L45, Y53, M264, P265, I266, T267, N268, D269, Q270, L273, L305, G307, D310, T311, P312, D344, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Host:  8 years

Epitope: Epitope of HPMV-4I3 Fab on HMPV F monomer
Chemical type: Discontinuous protein residues
Discontinuous residues: L19, K20, E21, E33, W284, K348, E349, N351, I352, I354, T356, N358, L378, Y409, T411, G432
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive

Epitope: Epitope of HPMV-4I3 Fab on HMPV F monomer
Chemical type: Discontinuous protein residues
Discontinuous residues: L19, K20, E21, E33, W284, K348, E349, N351, I352, I354, T356, N358, L378, Y409, T411, G432
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of HPMV-4I3 Fab on HMPV F monomer
Chemical type: Discontinuous protein residues
Discontinuous residues: L19, K20, E21, E33, W284, K348, E349, N351, I352, I354, T356, N358, L378, Y409, T411, G432
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive

Epitope: Epitope of HPMV-4I3 Fab on HMPV F monomer
Chemical type: Discontinuous protein residues
Discontinuous residues: L19, K20, E21, E33, W284, K348, E349, N351, I352, I354, T356, N358, L378, Y409, T411, G432
Source molecule (GenBank): ABD27846.1
Assay category: BCell
Result: Positive