Reference: Yan Wu; Carol Cain-Hom; Lisa Choy; Thijs J Hagenbeek; Gladys P de Leon; Yongmei Chen; David Finkle; Rayna Venook; Xiumin Wu; John Ridgway; Dorreyah Schahin-Reed; Graham J Dow; Amy Shelton; Scott Stawicki; Ryan J Watts; Jeff Zhang; Robert Choy; Peter Howard; Lisa Kadyk; Minhong Yan; Jiping Zha; Christopher A Callahan; Sarah G Hymowitz; Christian W Siebel. "Therapeutic antibody targeting of individual Notch receptors." Nature (2010).

Epitope: Epitope of anti-NRR1 on human Notch1 negative regulatory region (NRR1)
Chemical type: Discontinuous protein residues
Discontinuous residues: V1462, C1463, S1464, L1465, Q1466, N1468, W1497, K1498, Y1499, F1500, S1501, D1502, H1504, D1506, A1707, S1708, L1709, G1710, N1713, I1714, P1715, K1717
Source molecule (GenBank): P46531.4
Assay category: BCell
Result: Positive
Quantitative measurement: 3.1

Epitope: Epitope of anti-NRR1 on human Notch1 negative regulatory region (NRR1)
Chemical type: Discontinuous protein residues
Discontinuous residues: V1462, C1463, S1464, L1465, Q1466, N1468, W1497, K1498, Y1499, F1500, S1501, D1502, H1504, D1506, A1707, S1708, L1709, G1710, N1713, I1714, P1715, K1717
Source molecule (GenBank): P46531.4
Assay category: BCell
Result: Positive

Epitope: Epitope of anti-NRR1 on human Notch1 negative regulatory region (NRR1)
Chemical type: Discontinuous protein residues
Discontinuous residues: V1462, C1463, S1464, L1465, Q1466, N1468, W1497, K1498, Y1499, F1500, S1501, D1502, H1504, D1506, A1707, S1708, L1709, G1710, N1713, I1714, P1715, K1717
Source molecule (GenBank): P46531.4
Assay category: BCell
Result: Positive

Epitope: Epitope of anti-NRR1 on human Notch1 negative regulatory region (NRR1)
Chemical type: Discontinuous protein residues
Discontinuous residues: V1462, C1463, S1464, L1465, Q1466, N1468, W1497, K1498, Y1499, F1500, S1501, D1502, H1504, D1506, A1707, S1708, L1709, G1710, N1713, I1714, P1715, K1717
Source molecule (GenBank): P46531.4
Assay category: BCell
Result: Positive

Epitope: Epitope of anti-NRR1 on human Notch1 negative regulatory region (NRR1)
Chemical type: Discontinuous protein residues
Discontinuous residues: V1462, C1463, S1464, L1465, Q1466, N1468, W1497, K1498, Y1499, F1500, S1501, D1502, H1504, D1506, A1707, S1708, L1709, G1710, N1713, I1714, P1715, K1717
Source molecule (GenBank): P46531.4
Assay category: BCell
Result: Positive
Quantitative measurement: 2.19

Epitope: Epitope of anti-NRR1 on human Notch1 negative regulatory region (NRR1)
Chemical type: Discontinuous protein residues
Discontinuous residues: V1462, C1463, S1464, L1465, Q1466, N1468, W1497, K1498, Y1499, F1500, S1501, D1502, H1504, D1506, A1707, S1708, L1709, G1710, N1713, I1714, P1715, K1717
Source molecule (GenBank): P46531.4
Assay category: BCell
Result: Positive
Quantitative measurement: 87000.0

Epitope: Epitope of anti-NRR1 on human Notch1 negative regulatory region (NRR1)
Chemical type: Discontinuous protein residues
Discontinuous residues: V1462, C1463, S1464, L1465, Q1466, N1468, W1497, K1498, Y1499, F1500, S1501, D1502, H1504, D1506, A1707, S1708, L1709, G1710, N1713, I1714, P1715, K1717
Source molecule (GenBank): P46531.4
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00022

Epitope: Epitope of anti-NRR1 on human Notch1 negative regulatory region (NRR1)
Chemical type: Discontinuous protein residues
Discontinuous residues: V1462, C1463, S1464, L1465, Q1466, N1468, W1497, K1498, Y1499, F1500, S1501, D1502, H1504, D1506, A1707, S1708, L1709, G1710, N1713, I1714, P1715, K1717
Source molecule (GenBank): P46531.4
Assay category: BCell
Result: Positive
Quantitative measurement: 2.5

Epitope: Epitope of anti-NRR1 on human Notch1 negative regulatory region (NRR1)
Chemical type: Discontinuous protein residues
Discontinuous residues: V1462, C1463, S1464, L1465, Q1466, N1468, W1497, K1498, Y1499, F1500, S1501, D1502, H1504, D1506, A1707, S1708, L1709, G1710, N1713, I1714, P1715, K1717
Source molecule (GenBank): P46531.4
Assay category: BCell
Result: Positive
Quantitative measurement: 11000.0

Epitope: Epitope of anti-NRR1 on human Notch1 negative regulatory region (NRR1)
Chemical type: Discontinuous protein residues
Discontinuous residues: V1462, C1463, S1464, L1465, Q1466, N1468, W1497, K1498, Y1499, F1500, S1501, D1502, H1504, D1506, A1707, S1708, L1709, G1710, N1713, I1714, P1715, K1717
Source molecule (GenBank): P46531.4
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00034