Reference: Gerald P Linette; Michelle Becker-Hapak; Zachary L Skidmore; Miren Lorea Baroja; Chong Xu; Jasreet Hundal; David H Spencer; Weixuan Fu; Casey Cummins; Maya Robnett; Saghar Kaabinejadian; William H Hildebrand; Vincent Magrini; Ryan Demeter; Alexander S Krupnick; Obi L Griffith; Malachi Griffith; Elaine R Mardis; Beatriz M Carreno. "Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens." Proceedings of the National Academy of Sciences of the United States of America (2019).

Epitope: AKAP9
Chemical type: Peptide from protein
Sequence: RLSDLSEQL
Position: 958-966
Source molecule (GenBank): Q99996.4
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AKAP9
Chemical type: Peptide from protein
Sequence: RLSDLSEQL
Position: 958-966
Source molecule (GenBank): Q99996.4
Assay category: MhcLigandElution
Result: Positive

Epitope: PORCN
Chemical type: Peptide from protein
Sequence: LLHGFSFHL
Position: 339-347
Source molecule (GenBank): Q9H237.2
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PORCN
Chemical type: Peptide from protein
Sequence: LLHGFSFHL
Position: 339-347
Source molecule (GenBank): Q9H237.2
Assay category: MhcLigandElution
Result: Positive

Epitope: ZDBF2
Chemical type: Peptide from protein
Sequence: YISKYSVFL
Position: 2226-2234
Source molecule (GenBank): Q9HCK1.3
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TLE2
Chemical type: Peptide from protein
Sequence: LPRAKELIL
Position: 283-291
Source molecule (GenBank): Q04725.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SOCS6
Chemical type: Peptide from protein
Sequence: SLRSHHYSP
Position: 126-134
Source molecule (GenBank): O14544.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PORCN-H346Y
Chemical type: Peptide, no natural source
Sequence: LLHGFSFYL
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PORCN-H346Y
Chemical type: Peptide, no natural source
Sequence: LLHGFSFYL
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PORCN-H346Y
Chemical type: Peptide, no natural source
Sequence: LLHGFSFYL
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PORCN-H346Y
Chemical type: Peptide, no natural source
Sequence: LLHGFSFYL
Assay category: MhcLigandElution
Result: Positive

Epitope: PORCN-H346Y
Chemical type: Peptide, no natural source
Sequence: LLHGFSFYL
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 232.3

Epitope: ZDBF2-S2228L
Chemical type: Peptide, no natural source
Sequence: YILKYSVFL
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ZDBF2-S2228L
Chemical type: Peptide, no natural source
Sequence: YILKYSVFL
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ZDBF2-S2228L
Chemical type: Peptide, no natural source
Sequence: YILKYSVFL
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ZDBF2-S2228L
Chemical type: Peptide, no natural source
Sequence: YILKYSVFL
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 542.0

Epitope: GCN1L1-P274L
Chemical type: Peptide, no natural source
Sequence: SLLRSLENV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GCN1L1-P274L
Chemical type: Peptide, no natural source
Sequence: SLLRSLENV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GCN1L1-P274L
Chemical type: Peptide, no natural source
Sequence: SLLRSLENV
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GCN1L1-P274L
Chemical type: Peptide, no natural source
Sequence: SLLRSLENV
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 1315.2

Epitope: RASAL2-P637S
Chemical type: Peptide, no natural source
Sequence: IMSSSLFNL
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RASAL2-P637S
Chemical type: Peptide, no natural source
Sequence: IMSSSLFNL
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RASAL2-P637S
Chemical type: Peptide, no natural source
Sequence: IMSSSLFNL
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 184.9

Epitope: TLE2-E288K
Chemical type: Peptide, no natural source
Sequence: LPRAKKLIL
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TLE2-E288K
Chemical type: Peptide, no natural source
Sequence: LPRAKKLIL
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TLE2-E288K
Chemical type: Peptide, no natural source
Sequence: LPRAKKLIL
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TLE2-E288K
Chemical type: Peptide, no natural source
Sequence: LPRAKKLIL
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 264.2

Epitope: SOCS6-P134L
Chemical type: Peptide, no natural source
Sequence: SLRSHHYSL
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SOCS6-P134L
Chemical type: Peptide, no natural source
Sequence: SLRSHHYSL
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SOCS6-P134L
Chemical type: Peptide, no natural source
Sequence: SLRSHHYSL
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SOCS6-P134L
Chemical type: Peptide, no natural source
Sequence: SLRSHHYSL
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 216.8

Epitope: LRRC42-S85F
Chemical type: Peptide, no natural source
Sequence: NLRYFAKSL
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LRRC42-S85F
Chemical type: Peptide, no natural source
Sequence: NLRYFAKSL
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LRRC42-S85F
Chemical type: Peptide, no natural source
Sequence: NLRYFAKSL
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 194.1

Epitope: CDKN2A-P114L
Chemical type: Peptide, no natural source
Sequence: LLVDLAEEL
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Short Term Restimulated

Epitope: PDE7B-G113R
Chemical type: Peptide, no natural source
Sequence: RMWDFDIFL
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Short Term Restimulated

Epitope: PNPLA4-P100S
Chemical type: Peptide, no natural source
Sequence: ILSPSAHEL
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Short Term Restimulated

Epitope: POGK-P46L
Chemical type: Peptide, no natural source
Sequence: WVLALFDEV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: lung
Culture conditions: Short Term Restimulated

Epitope: DDX60-Y194H
Chemical type: Peptide, no natural source
Sequence: LPSMHRHQI
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 677.6

Epitope: ERCC6L V476I
Chemical type: Peptide, no natural source
Sequence: KIYRRQIFK
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ERCC6L V476I
Chemical type: Peptide, no natural source
Sequence: KIYRRQIFK
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ERCC6L V476I
Chemical type: Peptide, no natural source
Sequence: KIYRRQIFK
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2.287

Epitope: SMARCC2 S624F
Chemical type: Peptide, no natural source
Sequence: KVFEHVGSR
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SMARCC2 S624F
Chemical type: Peptide, no natural source
Sequence: KVFEHVGSR
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SMARCC2 S624F
Chemical type: Peptide, no natural source
Sequence: KVFEHVGSR
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2.932

Epitope: GPC1 P201L
Chemical type: Peptide, no natural source
Sequence: RLFGEAPREL
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GPC1 P201L
Chemical type: Peptide, no natural source
Sequence: RLFGEAPREL
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GPC1 P201L
Chemical type: Peptide, no natural source
Sequence: RLFGEAPREL
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 3.375

Epitope: MPV17 R75G
Chemical type: Peptide, no natural source
Sequence: VLDGFIPGT
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPV17 R75G
Chemical type: Peptide, no natural source
Sequence: VLDGFIPGT
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MPV17 R75G
Chemical type: Peptide, no natural source
Sequence: VLDGFIPGT
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2.958

Epitope: PRRC1 A431V
Chemical type: Peptide, no natural source
Sequence: QMIYSAARV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PRRC1 A431V
Chemical type: Peptide, no natural source
Sequence: QMIYSAARV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PRRC1 A431V
Chemical type: Peptide, no natural source
Sequence: QMIYSAARV
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 3.367

Epitope: RUFY1 K225N
Chemical type: Peptide, no natural source
Sequence: KLADYLNVL
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RUFY1 K225N
Chemical type: Peptide, no natural source
Sequence: KLADYLNVL
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RUFY1 K225N
Chemical type: Peptide, no natural source
Sequence: KLADYLNVL
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2.81

Epitope: SCYL1 P13L
Chemical type: Peptide, no natural source
Sequence: FLFELIPEP
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SCYL1 P13L
Chemical type: Peptide, no natural source
Sequence: FLFELIPEP
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SCYL1 P13L
Chemical type: Peptide, no natural source
Sequence: FLFELIPEP
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2.459

Epitope: SIPA1L3 S893F
Chemical type: Peptide, no natural source
Sequence: ILGIFNEFV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SIPA1L3 S893F
Chemical type: Peptide, no natural source
Sequence: ILGIFNEFV
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SIPA1L3 S893F
Chemical type: Peptide, no natural source
Sequence: ILGIFNEFV
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2.541

Epitope: TMEM48 F169L
Chemical type: Peptide, no natural source
Sequence: CLNEYHLFL
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: TMEM48 F169L
Chemical type: Peptide, no natural source
Sequence: CLNEYHLFL
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AKAP13 Q285K
Chemical type: Peptide, no natural source
Sequence: KLMNIQQKL
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AKAP13 Q285K
Chemical type: Peptide, no natural source
Sequence: KLMNIQQKL
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SEC24A P469L
Chemical type: Peptide, no natural source
Sequence: FLYNLLTRV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SEC24A P469L
Chemical type: Peptide, no natural source
Sequence: FLYNLLTRV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G209-2M
Chemical type: Peptide, no natural source
Sequence: IMDQVPFSV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G209-2M
Chemical type: Peptide, no natural source
Sequence: IMDQVPFSV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G280-9V
Chemical type: Peptide, no natural source
Sequence: YLEPGPVTV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G280-9V
Chemical type: Peptide, no natural source
Sequence: YLEPGPVTV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: DDX60 Y194H
Chemical type: Peptide, no natural source
Sequence: LPSMHRHQI
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2.831