Reference: Timothy T Spear; Kendra C Foley; Elizabeth Garrett-Mayer; Michael I Nishimura. "TCR modifications that enhance chain pairing in gene-modified T cells can augment cross-reactivity and alleviate CD8 dependence." Journal of leukocyte biology (2018).

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8-
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8-
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8-
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8-
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8-
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8-
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8-
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8-
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: HCV NS3:1406-1415
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1410-1419
Source molecule (GenBank): QGQ76726.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8-
Tissue: blood
Culture conditions: Engineered

Epitope: I1412L
Chemical type: Peptide from protein
Sequence: KLVALGLNAV
Position: 1406-1415
Source molecule (GenBank): ABR27393.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: I1412L
Chemical type: Peptide from protein
Sequence: KLVALGLNAV
Position: 1406-1415
Source molecule (GenBank): ABR27393.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: I1412L
Chemical type: Peptide from protein
Sequence: KLVALGLNAV
Position: 1406-1415
Source molecule (GenBank): ABR27393.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: I1412L
Chemical type: Peptide from protein
Sequence: KLVALGLNAV
Position: 1406-1415
Source molecule (GenBank): ABR27393.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: I1412L
Chemical type: Peptide from protein
Sequence: KLVALGLNAV
Position: 1406-1415
Source molecule (GenBank): ABR27393.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8-
Tissue: blood
Culture conditions: Engineered

Epitope: I1412L
Chemical type: Peptide from protein
Sequence: KLVALGLNAV
Position: 1406-1415
Source molecule (GenBank): ABR27393.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: V1408T
Chemical type: Peptide from protein
Sequence: KLTALGINAV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: V1408T
Chemical type: Peptide from protein
Sequence: KLTALGINAV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: V1408T
Chemical type: Peptide from protein
Sequence: KLTALGINAV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: V1408T
Chemical type: Peptide from protein
Sequence: KLTALGINAV
Assay category: TCell
Result: Positive
Cell type: T cell CD8-
Tissue: blood
Culture conditions: Engineered

Epitope: V1408T
Chemical type: Peptide from protein
Sequence: KLTALGINAV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: V1408T
Chemical type: Peptide from protein
Sequence: KLTALGINAV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: V1408L
Chemical type: Peptide from protein
Sequence: KLLALGINAV
Position: 1406-1415
Source molecule (GenBank): ABR27414.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: V1408L
Chemical type: Peptide from protein
Sequence: KLLALGINAV
Position: 1406-1415
Source molecule (GenBank): ABR27414.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: V1408L
Chemical type: Peptide from protein
Sequence: KLLALGINAV
Position: 1406-1415
Source molecule (GenBank): ABR27414.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: V1408L
Chemical type: Peptide from protein
Sequence: KLLALGINAV
Position: 1406-1415
Source molecule (GenBank): ABR27414.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: V1408L
Chemical type: Peptide from protein
Sequence: KLLALGINAV
Position: 1406-1415
Source molecule (GenBank): ABR27414.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8-
Tissue: blood
Culture conditions: Engineered

Epitope: V1408L
Chemical type: Peptide from protein
Sequence: KLLALGINAV
Position: 1406-1415
Source molecule (GenBank): ABR27414.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: V1408S/A1409S/I1412L/A1414S
Chemical type: Peptide from protein
Sequence: KLSSLGLNSV
Position: 1406-1415
Source molecule (GenBank): ABR27408.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: V1408S/A1409S/I1412L/A1414S
Chemical type: Peptide from protein
Sequence: KLSSLGLNSV
Position: 1406-1415
Source molecule (GenBank): ABR27408.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: V1408S/A1409S/I1412L/A1414S
Chemical type: Peptide from protein
Sequence: KLSSLGLNSV
Position: 1406-1415
Source molecule (GenBank): ABR27408.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: V1408S/A1409S/I1412L/A1414S
Chemical type: Peptide from protein
Sequence: KLSSLGLNSV
Position: 1406-1415
Source molecule (GenBank): ABR27408.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8-
Tissue: blood
Culture conditions: Engineered

Epitope: V1408S/A1409S/I1412L/A1414S
Chemical type: Peptide from protein
Sequence: KLSSLGLNSV
Position: 1406-1415
Source molecule (GenBank): ABR27408.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: V1408S/A1409S/I1412L/A1414S
Chemical type: Peptide from protein
Sequence: KLSSLGLNSV
Position: 1406-1415
Source molecule (GenBank): ABR27408.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered