Reference: Anthony E Zamora; Jeremy Chase Crawford; E Kaitlynn Allen; Xi-Zhi J Guo; Jesse Bakke; Robert A Carter; Hossam A Abdelsamed; Ardiana Moustaki; Yongjin Li; Ti-Cheng Chang; Walid Awad; Mari H Dallas; Charles G Mullighan; James R Downing; Terrence L Geiger; Taosheng Chen; Douglas R Green; Benjamin A Youngblood; Jinghui Zhang; Paul G Thomas. "Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8<sup>+</sup> T cell responses." Science translational medicine (2019).

Epitope: PLCD3_D314H mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KQHELMTLHGFMMYL
Assay category: TCell
Result: Negative
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLCD3_D314H mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KQHELMTLHGFMMYL
Assay category: TCell
Result: Negative
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLCD3_D314H mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KQHELMTLHGFMMYL
Assay category: TCell
Result: Negative
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLCD3_D314H mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KQHELMTLHGFMMYL
Assay category: TCell
Result: Negative
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLCD3_D314H mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KQHELMTLHGFMMYL
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3_D314H mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KQHELMTLHGFMMYL
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3_D314H mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KQHELMTLHGFMMYL
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3_D314H mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KQHELMTLHGFMMYL
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3_D314H mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KQHELMTLHGFMMYL
Assay category: TCell
Result: Positive
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3_D314H mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KQHELMTLHGFMMYL
Assay category: TCell
Result: Positive
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: EEF1A2_T142M mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: GQTREHALLAYMLGV
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: EEF1A2_T142M mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: GQTREHALLAYMLGV
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: EEF1A2_T142M mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: GQTREHALLAYMLGV
Assay category: TCell
Result: Negative
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SPATAS_S812C mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: IFKLQFHCMPVSNEV
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SPATAS_S812C mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: IFKLQFHCMPVSNEV
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SPATAS_S812C mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: IFKLQFHCMPVSNEV
Assay category: TCell
Result: Positive
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: MCTP1 _A899V mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: VQNILDEVVSFGERI
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: MCTP1 _A899V mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: VQNILDEVVSFGERI
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: MCTP1 _A899V mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: VQNILDEVVSFGERI
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: TECPR2_E1307A mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: PVGTAWAHVPGLQAC
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: TECPR2_E1307A mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: PVGTAWAHVPGLQAC
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: TECPR2_E1307A mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: PVGTAWAHVPGLQAC
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ETV6-RUNX1 15-mer
Chemical type: Peptide, no natural source
Sequence: AMPIGRIAECILGMN
Assay category: TCell
Result: Positive
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ETV6-RUNX1 15-mer
Chemical type: Peptide, no natural source
Sequence: AMPIGRIAECILGMN
Assay category: TCell
Result: Positive
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ETV6-RUNX1 15-mer
Chemical type: Peptide, no natural source
Sequence: AMPIGRIAECILGMN
Assay category: TCell
Result: Positive
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ETV6-RUNX1 15-mer
Chemical type: Peptide, no natural source
Sequence: AMPIGRIAECILGMN
Assay category: TCell
Result: Positive
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ETV6-RUNX1 15-mer
Chemical type: Peptide, no natural source
Sequence: AMPIGRIAECILGMN
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ETV6-RUNX1 15-mer
Chemical type: Peptide, no natural source
Sequence: AMPIGRIAECILGMN
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PCNXL2_ F118L mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: VAHLMWLERLYVWLQ
Assay category: TCell
Result: Positive
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PCNXL2_ F118L mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: VAHLMWLERLYVWLQ
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PCNXL2_ F118L mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: VAHLMWLERLYVWLQ
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PRRC2B_R923W mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: SSEPEWTPEPWSSSS
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PRRC2B_R923W mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: SSEPEWTPEPWSSSS
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PRRC2B_R923W mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: SSEPEWTPEPWSSSS
Assay category: TCell
Result: Positive
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: AHNAK_S5863F mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: GVSLASKKSRLFSSS
Assay category: TCell
Result: Positive
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: AHNAK_S5863F mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: GVSLASKKSRLFSSS
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: AHNAK_S5863F mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: GVSLASKKSRLFSSS
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139_A298T_var1 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KRFRTMAATTLKAFF
Assay category: TCell
Result: Negative
MHC allele types: 1017 211 44 259 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139_A298T_var1 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KRFRTMAATTLKAFF
Assay category: TCell
Result: Negative
MHC allele types: 1017 211 44 259 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139_A298T_var1 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KRFRTMAATTLKAFF
Assay category: TCell
Result: Negative
MHC allele types: 1017 211 44 259 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SCD_E240K_var1 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: PTLVPWYFWGKTFQN
Assay category: TCell
Result: Negative
MHC allele types: 1017 211 44 259 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SCD_E240K_var1 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: PTLVPWYFWGKTFQN
Assay category: TCell
Result: Negative
MHC allele types: 1017 211 44 259 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SCD_E240K_var1 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: PTLVPWYFWGKTFQN
Assay category: TCell
Result: Negative
MHC allele types: 1017 211 44 259 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: BTBD16_V298M_var1 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: IQAIPTYETMMTFFK
Assay category: TCell
Result: Negative
MHC allele types: 1017 211 44 259 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: BTBD16_V298M_var1 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: IQAIPTYETMMTFFK
Assay category: TCell
Result: Negative
MHC allele types: 1017 211 44 259 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: BTBD16_V298M_var1 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: IQAIPTYETMMTFFK
Assay category: TCell
Result: Negative
MHC allele types: 1017 211 44 259 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ACE2_061SY_var1 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: SPYAYQSIKVRISLK
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ACE2_061SY_var1 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: SPYAYQSIKVRISLK
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ACE2_061SY_var1 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: SPYAYQSIKVRISLK
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: MCTP1_R783H mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: LRNFIRMKHCVMVLV
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: MCTP1_R783H mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: LRNFIRMKHCVMVLV
Assay category: TCell
Result: Positive
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: MCTP1_R783H mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: LRNFIRMKHCVMVLV
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: NUDT10_A62V mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: EPEEEPGGAVVREVY
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: NUDT10_A62V mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: EPEEEPGGAVVREVY
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: NUDT10_A62V mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: EPEEEPGGAVVREVY
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: FMOD_I117T mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: VYFFQNNQTTSIQEG
Assay category: TCell
Result: Negative
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: FMOD_I117T mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: VYFFQNNQTTSIQEG
Assay category: TCell
Result: Negative
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: FMOD_I117T mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: VYFFQNNQTTSIQEG
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ACE2_061SY_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: GWSTDWSPYAYQSIK
Assay category: TCell
Result: Negative
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ACE2_061SY_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: GWSTDWSPYAYQSIK
Assay category: TCell
Result: Negative
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ACE2_061SY_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: GWSTDWSPYAYQSIK
Assay category: TCell
Result: Negative
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ANKS1A_E434K mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KYFPLTASKVLSMRP
Assay category: TCell
Result: Positive
MHC allele types: 200 32 195 932 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ANKS1A_E434K mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KYFPLTASKVLSMRP
Assay category: TCell
Result: Positive
MHC allele types: 200 32 195 932 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ANKS1A_E434K mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KYFPLTASKVLSMRP
Assay category: TCell
Result: Positive
MHC allele types: 200 32 195 932 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ASXL3_E1718K mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: STSSPMEKAISLATD
Assay category: TCell
Result: Positive
MHC allele types: 200 32 195 932 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ASXL3_E1718K mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: STSSPMEKAISLATD
Assay category: TCell
Result: Positive
MHC allele types: 200 32 195 932 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ASXL3_E1718K mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: STSSPMEKAISLATD
Assay category: TCell
Result: Positive
MHC allele types: 200 32 195 932 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PDS5B_D86H mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: RLLVACCLAHIFRIY
Assay category: TCell
Result: Positive
MHC allele types: 200 32 195 932 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PDS5B_D86H mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: RLLVACCLAHIFRIY
Assay category: TCell
Result: Positive
MHC allele types: 200 32 195 932 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PDS5B_D86H mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: RLLVACCLAHIFRIY
Assay category: TCell
Result: Positive
MHC allele types: 200 32 195 932 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: RBCK1 _L130V mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: AYLYVLSARNTSLNP
Assay category: TCell
Result: Positive
MHC allele types: 200 32 195 932 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: RBCK1 _L130V mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: AYLYVLSARNTSLNP
Assay category: TCell
Result: Positive
MHC allele types: 200 32 195 932 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: RBCK1 _L130V mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: AYLYVLSARNTSLNP
Assay category: TCell
Result: Positive
MHC allele types: 200 32 195 932 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: IPO13_I267M mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: AIVNAMSQPDAQRYV
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: IPO13_I267M mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: AIVNAMSQPDAQRYV
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: IPO13_I267M mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: AIVNAMSQPDAQRYV
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: FAM157B_L156F mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: EFFRFLHDLHLLAFA
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: FAM157B_L156F mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: EFFRFLHDLHLLAFA
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: FAM157B_L156F mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: EFFRFLHDLHLLAFA
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GRIN3A_A401T mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: ELVARAVTTATMIQP
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GRIN3A_A401T mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: ELVARAVTTATMIQP
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GRIN3A_A401T mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: ELVARAVTTATMIQP
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SPIRE1_R332W mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: VMVNGDIPPWLKKSA
Assay category: TCell
Result: Negative
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: SPIRE1_R332W mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: VMVNGDIPPWLKKSA
Assay category: TCell
Result: Negative
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: SPIRE1_R332W mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: VMVNGDIPPWLKKSA
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SPIRE1_R332W mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: VMVNGDIPPWLKKSA
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SPIRE1_R332W mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: VMVNGDIPPWLKKSA
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: CD101_S889F mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: RHLHCYRSSFTDFVL
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: CD101_S889F mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: RHLHCYRSSFTDFVL
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: CD101_S889F mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: RHLHCYRSSFTDFVL
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: AZI1_M681I mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KKLKELISATEKARR
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: AZI1_M681I mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KKLKELISATEKARR
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: AZI1_M681I mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: KKLKELISATEKARR
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: TMEM104_V281I mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: RNLFGVCIYSFMCQH
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: TMEM104_V281I mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: RNLFGVCIYSFMCQH
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: TMEM104_V281I mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: RNLFGVCIYSFMCQH
Assay category: TCell
Result: Positive
MHC allele types: 215 231 44 257 307 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3 WT 15-mer
Chemical type: Peptide from protein
Sequence: KQHELMTLDGFMMYL
Position: 306-320
Source molecule (GenBank): Q8N3E9.3
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3 WT 15-mer
Chemical type: Peptide from protein
Sequence: KQHELMTLDGFMMYL
Position: 306-320
Source molecule (GenBank): Q8N3E9.3
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3 WT 15-mer
Chemical type: Peptide from protein
Sequence: KQHELMTLDGFMMYL
Position: 306-320
Source molecule (GenBank): Q8N3E9.3
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3 WT 15-mer
Chemical type: Peptide from protein
Sequence: KQHELMTLDGFMMYL
Position: 306-320
Source molecule (GenBank): Q8N3E9.3
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139 WT 15-mer
Chemical type: Peptide from protein
Sequence: KRFRTMAAATLKAFF
Position: 290-304
Source molecule (GenBank): A0A0I9QQP3.1
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139 WT 15-mer
Chemical type: Peptide from protein
Sequence: KRFRTMAAATLKAFF
Position: 290-304
Source molecule (GenBank): A0A0I9QQP3.1
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139 WT 15-mer
Chemical type: Peptide from protein
Sequence: KRFRTMAAATLKAFF
Position: 290-304
Source molecule (GenBank): A0A0I9QQP3.1
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139 WT 15-mer
Chemical type: Peptide from protein
Sequence: KRFRTMAAATLKAFF
Position: 290-304
Source molecule (GenBank): A0A0I9QQP3.1
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SPIRE1 WT 15-mer
Chemical type: Peptide from protein
Sequence: VMVNGDIPPRLKKSA
Position: 323-337
Source molecule (GenBank): Q08AE8.3
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SPIRE1 WT 15-mer
Chemical type: Peptide from protein
Sequence: VMVNGDIPPRLKKSA
Position: 323-337
Source molecule (GenBank): Q08AE8.3
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3(311−319)MUT
Chemical type: Peptide, no natural source
Sequence: MTLHGFMMY
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3(311−319)MUT
Chemical type: Peptide, no natural source
Sequence: MTLHGFMMY
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139(293-301)MUT
Chemical type: Peptide, no natural source
Sequence: RTMAATTLK
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3(311−319)PAR
Chemical type: Peptide from protein
Sequence: MTLDGFMMY
Position: 311-319
Source molecule (GenBank): Q8N3E9.3
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3(312−320)MUT
Chemical type: Peptide, no natural source
Sequence: TLHGFMMYL
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139(293-301)PAR
Chemical type: Peptide from protein
Sequence: RTMAAATLK
Position: 293-301
Source molecule (GenBank): A0A0I9QQP3.1
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139(297-305)PAR
Chemical type: Peptide from protein
Sequence: AATLKAFFK
Position: 297-305
Source molecule (GenBank): A0A0I9QQP3.1
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139(297-305)MUT
Chemical type: Peptide, no natural source
Sequence: ATTLKAFFK
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3(308-316)MUT
Chemical type: Peptide, no natural source
Sequence: HELMTLHGF
Assay category: TCell
Result: Negative
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3(308-317)MUT
Chemical type: Peptide, no natural source
Sequence: HELMTLHGFM
Assay category: TCell
Result: Negative
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: EEF1A2(134-142)MUT
Chemical type: Peptide, no natural source
Sequence: REHALLAYM
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: MCTP1(779-787)MUT
Chemical type: Peptide, no natural source
Sequence: IRMKHCVMV
Assay category: TCell
Result: Negative
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ACE2(614-622)MUT
Chemical type: Peptide, no natural source
Sequence: AYQSIKVRI
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ETV6/RUNX1(336/20)
Chemical type: Peptide, no natural source
Sequence: RIAECILGM
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ETV6/RUNX1(336/20)
Chemical type: Peptide, no natural source
Sequence: RIAECILGM
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ETV6/RUNX1(336/20)
Chemical type: Peptide, no natural source
Sequence: RIAECILGM
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ETV6/RUNX1(336/20)
Chemical type: Peptide, no natural source
Sequence: RIAECILGM
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ETV6/RUNX1(336/20)
Chemical type: Peptide, no natural source
Sequence: RIAECILGM
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PCNXL2(1176-1184)MUT
Chemical type: Peptide, no natural source
Sequence: HLMWLERLY
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ANKS1A(428-436)MUT
Chemical type: Peptide, no natural source
Sequence: FPLTASKVL
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ASXL3(1714-1722)MUT
Chemical type: Peptide, no natural source
Sequence: SPMEKAISL
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ATP13A4(107-115)MUT
Chemical type: Peptide, no natural source
Sequence: HPFMTDEEY
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SLC6A7(57-65) MUT
Chemical type: Peptide, no natural source
Sequence: LGNVWCFPY
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: DTX3L(139-147)MUT
Chemical type: Peptide, no natural source
Sequence: TAHLNCNLF
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: IPO13(267-275)MUT
Chemical type: Peptide, no natural source
Sequence: MSQPDAQRY
Assay category: TCell
Result: Negative
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: FAM157B(155-163)MUT
Chemical type: Peptide, no natural source
Sequence: RFLHDLHLL
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: CD101(884-892)MUT
Chemical type: Peptide, no natural source
Sequence: HLHCYRSSF
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: TMEM104(276-284)MUT
Chemical type: Peptide, no natural source
Sequence: LFGVCIYSF
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo