Reference: M Shenoy; M Oshima; M Z Atassi; P Christadoss. "Suppression of experimental autoimmune myasthenia gravis by epitope-specific neonatal tolerance to synthetic region alpha 146-162 of acetylcholine receptor." Clinical immunology and immunopathology (1993).

Epitope: tAChR α1-16
Chemical type: Peptide from protein
Sequence: SEHETRLVANLLENYN
Position: 25-40
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α1-16
Chemical type: Peptide from protein
Sequence: SEHETRLVANLLENYN
Position: 25-40
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α12-27
Chemical type: Peptide from protein
Sequence: LENYNKVIRPVEHHTH
Position: 36-51
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α12-27
Chemical type: Peptide from protein
Sequence: LENYNKVIRPVEHHTH
Position: 36-51
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α23-38
Chemical type: Peptide from protein
Sequence: EHHTHFVDITVGLQLI
Position: 47-62
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α23-38
Chemical type: Peptide from protein
Sequence: EHHTHFVDITVGLQLI
Position: 47-62
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α34-49
Chemical type: Peptide from protein
Sequence: GLQLIQLISVDEVNQI
Position: 58-73
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α34-49
Chemical type: Peptide from protein
Sequence: GLQLIQLISVDEVNQI
Position: 58-73
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α45-60
Chemical type: Peptide from protein
Sequence: EVNQIVETNVRLRQQW
Position: 69-84
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α45-60
Chemical type: Peptide from protein
Sequence: EVNQIVETNVRLRQQW
Position: 69-84
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α56-71
Chemical type: Peptide from protein
Sequence: LRQQWIDVRLRWNPAD
Position: 80-95
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α56-71
Chemical type: Peptide from protein
Sequence: LRQQWIDVRLRWNPAD
Position: 80-95
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α78-93
Chemical type: Peptide from protein
Sequence: IRLPSDDVWLPDLVLY
Position: 102-117
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α78-93
Chemical type: Peptide from protein
Sequence: IRLPSDDVWLPDLVLY
Position: 102-117
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α100-115
Chemical type: Peptide from protein
Sequence: FAIVHMTKLLLDYTGK
Position: 124-139
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α100-115
Chemical type: Peptide from protein
Sequence: FAIVHMTKLLLDYTGK
Position: 124-139
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α111-126
Chemical type: Peptide from protein
Sequence: DYTGKIMWTPPAIFKS
Position: 135-150
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α111-126
Chemical type: Peptide from protein
Sequence: DYTGKIMWTPPAIFKS
Position: 135-150
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α122-138
Chemical type: Peptide from protein
Sequence: AIFKSYCEIIVTHFPFD
Position: 146-162
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α122-138
Chemical type: Peptide from protein
Sequence: AIFKSYCEIIVTHFPFD
Position: 146-162
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α134-150
Chemical type: Peptide from protein
Sequence: HFPFDQQNCTMKLGIWT
Position: 158-174
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α134-150
Chemical type: Peptide from protein
Sequence: HFPFDQQNCTMKLGIWT
Position: 158-174
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): P02710.1
Assay category: BCell
Result: Positive
Host: F 8 weeks

Epitope: tAChR α146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): P02710.1
Assay category: BCell
Result: Positive
Host: F <24 hours

Epitope: tAChR α146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F <1 day
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F <1 day
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F <1 day

Epitope: tAChR α146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive-High
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α146-162
Chemical type: Peptide from protein
Sequence: LGIWTYDGTKVSISPES
Position: 170-186
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α158-174
Chemical type: Peptide from protein
Sequence: IWTYDGTKVSISPESDRPDLSTFMESG
Position: 172-198
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α158-174
Chemical type: Peptide from protein
Sequence: IWTYDGTKVSISPESDRPDLSTFMESG
Position: 172-198
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α170-186
Chemical type: Peptide from protein
Sequence: FMESGEWVMKDYRGWKH
Position: 194-210
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α170-186
Chemical type: Peptide from protein
Sequence: FMESGEWVMKDYRGWKH
Position: 194-210
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α182-198
Chemical type: Peptide from protein
Sequence: RGWKHWVYYTCCPDTPY
Position: 206-222
Source molecule (GenBank): P02710.1
Assay category: BCell
Result: Positive
Host: F 8 weeks

Epitope: tAChR α182-198
Chemical type: Peptide from protein
Sequence: RGWKHWVYYTCCPDTPY
Position: 206-222
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α182-198
Chemical type: Peptide from protein
Sequence: RGWKHWVYYTCCPDTPY
Position: 206-222
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive-High
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α182-198
Chemical type: Peptide from protein
Sequence: RGWKHWVYYTCCPDTPY
Position: 206-222
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α194-210
Chemical type: Peptide from protein
Sequence: PDTPYLDITYHFIMQRI
Position: 218-234
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α194-210
Chemical type: Peptide from protein
Sequence: PDTPYLDITYHFIMQRI
Position: 218-234
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: human AChR α182-198
Chemical type: Peptide from protein
Sequence: RGWKHSVTYSCCPDTPY
Position: 227-243
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Positive
Host: F <24 hours

Epitope: human AChR α182-198
Chemical type: Peptide from protein
Sequence: RGWKHSVTYSCCPDTPY
Position: 227-243
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: human AChR α182-198
Chemical type: Peptide from protein
Sequence: RGWKHSVTYSCCPDTPY
Position: 227-243
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: human AChR α182-198
Chemical type: Peptide from protein
Sequence: RGWKHSVTYSCCPDTPY
Position: 227-243
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host: F <1 day