Reference: T M Redmond; H Sanui; L H Hu; B Wiggert; H Margalit; J A Berzofsky; G J Chader; I Gery. "Immune responses to peptides derived from the retinal protein IRBP: immunopathogenic determinants are not necessarily immunodominant." Clinical immunology and immunopathology (1989).

Epitope: R1
Chemical type: Peptide from protein
Sequence: SQLEGERYGSKKSM
Position: 1124-1137
Source molecule (GenBank): NP_776589.1
Assay category: BCell
Result: Negative
Host: M 8-12 weeks

Epitope: R2
Chemical type: Peptide from protein
Sequence: DKIYNRPNNSVSEL
Position: 1107-1120
Source molecule (GenBank): NP_776589.1
Assay category: BCell
Result: Negative
Host: M 8-12 weeks

Epitope: R3
Chemical type: Peptide from protein
Sequence: KRLGRALVIGEVTSGGCQPPQTY
Position: 1157-1179
Source molecule (GenBank): NP_776589.1
Assay category: BCell
Result: Positive
Host: M 8-12 weeks

Epitope: R3
Chemical type: Peptide from protein
Sequence: KRLGRALVIGEVTSGGCQPPQTY
Position: 1157-1179
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: R3
Chemical type: Peptide from protein
Sequence: KRLGRALVIGEVTSGGCQPPQTY
Position: 1157-1179
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Negative
Host: M 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: R4
Chemical type: Peptide from protein
Sequence: HVDDTDLYLTIPTARSVGAADGS
Position: 1180-1202
Source molecule (GenBank): NP_776589.1
Assay category: BCell
Result: Negative
Host: M 8-12 weeks

Epitope: R4
Chemical type: Peptide from protein
Sequence: HVDDTDLYLTIPTARSVGAADGS
Position: 1180-1202
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Negative
Host: M 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: R4
Chemical type: Peptide from protein
Sequence: HVDDTDLYLTIPTARSVGAADGS
Position: 1180-1202
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks

Epitope: R4
Chemical type: Peptide from protein
Sequence: HVDDTDLYLTIPTARSVGAADGS
Position: 1180-1202
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: R4
Chemical type: Peptide from protein
Sequence: HVDDTDLYLTIPTARSVGAADGS
Position: 1180-1202
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Negative
Host: M 8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: R4
Chemical type: Peptide from protein
Sequence: HVDDTDLYLTIPTARSVGAADGS
Position: 1180-1202
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: R5
Chemical type: Peptide from protein
Sequence: ELLTQVSELLVEHVWKK
Position: 1052-1068
Source molecule (GenBank): NP_776589.1
Assay category: BCell
Result: Negative
Host: M 8-12 weeks

Epitope: R5
Chemical type: Peptide from protein
Sequence: ELLTQVSELLVEHVWKK
Position: 1052-1068
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: R5
Chemical type: Peptide from protein
Sequence: ELLTQVSELLVEHVWKK
Position: 1052-1068
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Negative
Host: M 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: R6
Chemical type: Peptide from protein
Sequence: GPTSSISALCSYFFDE
Position: 1085-1100
Source molecule (GenBank): NP_776589.1
Assay category: BCell
Result: Negative
Host: M 8-12 weeks

Epitope: R6
Chemical type: Peptide from protein
Sequence: GPTSSISALCSYFFDE
Position: 1085-1100
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: R6
Chemical type: Peptide from protein
Sequence: GPTSSISALCSYFFDE
Position: 1085-1100
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Negative
Host: M 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: R7
Chemical type: Peptide from protein
Sequence: EFTYIMKRLGRALV
Position: 1151-1164
Source molecule (GenBank): NP_776589.1
Assay category: BCell
Result: Negative
Host: M 8-12 weeks

Epitope: R7
Chemical type: Peptide from protein
Sequence: EFTYIMKRLGRALV
Position: 1151-1164
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Negative
Host: M 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: R7
Chemical type: Peptide from protein
Sequence: EFTYIMKRLGRALV
Position: 1151-1164
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Negative
Host: M 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: R9
Chemical type: Peptide from protein
Sequence: PQTYHVDDTDLYLTIPTARSVGAADGS
Position: 1176-1202
Source molecule (GenBank): NP_776589.1
Assay category: BCell
Result: Negative
Host: M 8-12 weeks

Epitope: R9
Chemical type: Peptide from protein
Sequence: PQTYHVDDTDLYLTIPTARSVGAADGS
Position: 1176-1202
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Positive
Host: M 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: R9
Chemical type: Peptide from protein
Sequence: PQTYHVDDTDLYLTIPTARSVGAADGS
Position: 1176-1202
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Negative
Host: M 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: R10
Chemical type: Peptide from protein
Sequence: PTARSVGAADGSSWEGVGVV
Position: 1191-1210
Source molecule (GenBank): NP_776589.1
Assay category: BCell
Result: Negative
Host: M 8-12 weeks

Epitope: R10
Chemical type: Peptide from protein
Sequence: PTARSVGAADGSSWEGVGVV
Position: 1191-1210
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Negative
Host: M 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: R10
Chemical type: Peptide from protein
Sequence: PTARSVGAADGSSWEGVGVV
Position: 1191-1210
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Negative
Host: M 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo