Reference: Katja G Schmidt; Paulina Geißler; Ev-Marie Schuster; Christine Schülein; Ellen G Harrer; Verena Schönau; Markus Luber; Bernd Spriewald; Philipp Steininger; Silke Bergmann; Armin Ensser; Kilian Schober; Krystelle Nganou-Makamdop; Thomas Harrer. "Coronavirus replicase epitopes induce cross-reactive CD8 T cell responses in SARS-CoV-2-naive people with HIV-1." iScience (2025).

Epitope: RF16
Chemical type: Peptide from protein
Sequence: RWVLNNDYYRSLPGVF
Position: 3003-3018
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: RF16
Chemical type: Peptide from protein
Sequence: RWVLNNDYYRSLPGVF
Position: 3003-3018
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: KL17
Chemical type: Peptide from protein
Sequence: KVTSAMQTMLFTMLRKL
Position: 4024-4040
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: GY18
Chemical type: Peptide from protein
Sequence: GIVGVLTLDNQDLNGNWY
Position: 4592-4609
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: GY18
Chemical type: Peptide from protein
Sequence: GIVGVLTLDNQDLNGNWY
Position: 4592-4609
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: DF14
Chemical type: Peptide from protein
Sequence: DRCILHCANFNVLF
Position: 4696-4709
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TV20
Chemical type: Peptide from protein
Sequence: TITQMNLKYAISAKNRARTV
Position: 4930-4949
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TV20
Chemical type: Peptide from protein
Sequence: TITQMNLKYAISAKNRARTV
Position: 4930-4949
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: II15
Chemical type: Peptide from protein
Sequence: ISAKNRARTVAGVSI
Position: 4940-4954
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: II15
Chemical type: Peptide from protein
Sequence: ISAKNRARTVAGVSI
Position: 4940-4954
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HI20
Chemical type: Peptide from protein
Sequence: HLMGWDYPKCDRAMPNMLRI
Position: 5005-5024
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HI20
Chemical type: Peptide from protein
Sequence: HLMGWDYPKCDRAMPNMLRI
Position: 5005-5024
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HC20
Chemical type: Peptide from protein
Sequence: HRFYRLANECAQVLSEMVMC
Position: 5042-5061
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HC20
Chemical type: Peptide from protein
Sequence: HRFYRLANECAQVLSEMVMC
Position: 5042-5061
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: LS20
Chemical type: Peptide from protein
Sequence: LYVKPGGTSSGDATTAYANS
Position: 5065-5084
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: GV18
Chemical type: Peptide from protein
Sequence: GDATTAYANSVFNICQAV
Position: 5075-5092
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: SK15
Chemical type: Peptide from protein
Sequence: SVLYYQNNVFMSEAK
Position: 5176-5190
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: SK15
Chemical type: Peptide from protein
Sequence: SVLYYQNNVFMSEAK
Position: 5176-5190
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: VV22
Chemical type: Peptide from protein
Sequence: VYLPYPDPSRILGAGCFVDDIV
Position: 5219-5240
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: VV22
Chemical type: Peptide from protein
Sequence: VYLPYPDPSRILGAGCFVDDIV
Position: 5219-5240
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: GL18
Chemical type: Peptide from protein
Sequence: GTLMIERFVSLAIDAYPL
Position: 5244-5261
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: GL18
Chemical type: Peptide from protein
Sequence: GTLMIERFVSLAIDAYPL
Position: 5244-5261
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TY21
Chemical type: Peptide from protein
Sequence: TLQGPPGTGKSHFAIGLALYY
Position: 5603-5623
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: AL20
Chemical type: Peptide from protein
Sequence: AKHYVYIGDPAQLPAPRTLL
Position: 5717-5736
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: AL20
Chemical type: Peptide from protein
Sequence: AKHYVYIGDPAQLPAPRTLL
Position: 5717-5736
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: CA20
Chemical type: Peptide from protein
Sequence: CPAEIVDTVSALVYDNKLKA
Position: 5768-5787
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: CA20
Chemical type: Peptide from protein
Sequence: CPAEIVDTVSALVYDNKLKA
Position: 5768-5787
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NM20
Chemical type: Peptide from protein
Sequence: NVNRFNVAITRAKVGILCIM
Position: 5881-5900
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: NM20
Chemical type: Peptide from protein
Sequence: NVNRFNVAITRAKVGILCIM
Position: 5881-5900
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: RM11
Chemical type: Peptide from protein
Sequence: RRLISMMGFKM
Position: 5977-5987
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: CV14
Chemical type: Peptide from protein
Sequence: CVCSVIDLLLDDFV
Position: 6742-6755
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: QI13
Chemical type: Peptide from protein
Sequence: QKLALGGSVAIKI
Position: 6957-6969
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: CV9
Chemical type: Peptide from protein
Sequence: CPAEIVDTV
Position: 5768-5776
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: SF10
Chemical type: Peptide from protein
Sequence: SVLYYQNNVF
Position: 5176-5185
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: QF10
Chemical type: Peptide from protein
Sequence: QVLYYQNNVF
Position: 5149-5158
Source molecule (GenBank): P0C6X6
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TM11
Chemical type: Peptide from protein
Sequence: TRAKVGILCIM
Position: 5890-5900
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: YL8 D/N
Chemical type: Peptide from protein
Sequence: YPNPSRIL
Position: 5196-5203
Source molecule (GenBank): P0C6X6
Assay category: MhcBinding
Result: Positive