Reference: Katharina Ochs; Martina Ott; Theresa Bunse; Felix Sahm; Lukas Bunse; Katrin Deumelandt; Jana K Sonner; Melanie Keil; Andreas von Deimling; Wolfgang Wick; Michael Platten. "K27M-mutant histone-3 as a novel target for glioma immunotherapy." Oncoimmunology (2017).

Epitope: H3 wt p14-40
Chemical type: Peptide from protein
Sequence: KAPRKQLATKAARKSAPSTGGVKKPHR
Position: 15-41
Source molecule (GenBank): K7EK07.1
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H3 wt p14-40
Chemical type: Peptide from protein
Sequence: KAPRKQLATKAARKSAPSTGGVKKPHR
Position: 15-41
Source molecule (GenBank): K7EK07.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H3K27M p14-40
Chemical type: Peptide, no natural source
Sequence: KAPRKQLATKAARMSAPSTGGVKKPHR
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Culture conditions: Direct Ex Vivo

Epitope: H3K27M p14-40
Chemical type: Peptide, no natural source
Sequence: KAPRKQLATKAARMSAPSTGGVKKPHR
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H3K27M p14-40
Chemical type: Peptide, no natural source
Sequence: KAPRKQLATKAARMSAPSTGGVKKPHR
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H3K27M p14-40
Chemical type: Peptide, no natural source
Sequence: KAPRKQLATKAARMSAPSTGGVKKPHR
Assay category: TCell
Result: Positive

Epitope: H3K27M p14-40
Chemical type: Peptide, no natural source
Sequence: KAPRKQLATKAARMSAPSTGGVKKPHR
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Culture conditions: Direct Ex Vivo

Epitope: H3K27M p14-40
Chemical type: Peptide, no natural source
Sequence: KAPRKQLATKAARMSAPSTGGVKKPHR
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H3K27M p14-40
Chemical type: Peptide, no natural source
Sequence: KAPRKQLATKAARMSAPSTGGVKKPHR
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H3 wt p26-35
Chemical type: Peptide from protein
Sequence: RKSAPSTGGV
Position: 27-36
Source molecule (GenBank): K7EK07.1
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H3 wt p26-35
Chemical type: Peptide from protein
Sequence: RKSAPSTGGV
Position: 27-36
Source molecule (GenBank): K7EK07.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H3 wt p26-35
Chemical type: Peptide from protein
Sequence: RKSAPSTGGV
Position: 27-36
Source molecule (GenBank): K7EK07.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H3K27M p26-35
Chemical type: Peptide, no natural source
Sequence: RMSAPSTGGV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H3K27M p26-35
Chemical type: Peptide, no natural source
Sequence: RMSAPSTGGV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H3K27M p26-35
Chemical type: Peptide, no natural source
Sequence: RMSAPSTGGV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H3K27M p26-35
Chemical type: Peptide, no natural source
Sequence: RMSAPSTGGV
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: H3K27M p26-35
Chemical type: Peptide, no natural source
Sequence: RMSAPSTGGV
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H3K27M p26-35
Chemical type: Peptide, no natural source
Sequence: RMSAPSTGGV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H3K27M p26-35
Chemical type: Peptide, no natural source
Sequence: RMSAPSTGGV
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo