Reference: Leo Swadling; Mariana O Diniz; Nathalie M Schmidt; Oliver E Amin; Aneesh Chandran; Emily Shaw; Corinna Pade; Joseph M Gibbons; Nina Le Bert; Anthony T Tan; Anna Jeffery-Smith; Cedric C S Tan; Christine Y L Tham; Stephanie Kucykowicz; Gloryanne Aidoo-Micah; Joshua Rosenheim; Jessica Davies; Marina Johnson; Melanie P Jensen; George Joy; Laura E McCoy; Ana M Valdes; Benjamin M Chain; David Goldblatt; Daniel M Altmann; Rosemary J Boyton; Charlotte Manisty; Thomas A Treibel; James C Moon; Lucy van Dorp; Francois Balloux; Áine McKnight; Mahdad Noursadeghi; Antonio Bertoletti; Mala K Maini. "Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2." Nature (2022).

Epitope: NSP7-5a
Chemical type: Peptide from protein
Sequence: KLWAQCVQL
Position: 3886-3894
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP7-5a
Chemical type: Peptide from protein
Sequence: KLWAQCVQL
Position: 3886-3894
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NSP7-5a
Chemical type: Peptide from protein
Sequence: KLWAQCVQL
Position: 3886-3894
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP7-5a
Chemical type: Peptide from protein
Sequence: KLWAQCVQL
Position: 3886-3894
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NSP7-5a
Chemical type: Peptide from protein
Sequence: KLWAQCVQL
Position: 3886-3894
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP7-5c
Chemical type: Peptide from protein
Sequence: KLWQYCSVL
Position: 3951-3959
Source molecule (GenBank): ADN03337.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP7-5c
Chemical type: Peptide from protein
Sequence: KLWQYCSVL
Position: 3951-3959
Source molecule (GenBank): ADN03337.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NSP7-5c
Chemical type: Peptide from protein
Sequence: KLWQYCSVL
Position: 3951-3959
Source molecule (GenBank): ADN03337.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP7-5b
Chemical type: Peptide from protein
Sequence: KLWHYCSTL
Position: 3863-3871
Source molecule (GenBank): P0C6X6
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP7-5d
Chemical type: Peptide from protein
Sequence: SEWAYCVDL
Position: 3548-3556
Source molecule (GenBank): P0C6U6.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP7-5e
Chemical type: Peptide from protein
Sequence: KEWAYCVEM
Position: 3578-3586
Source molecule (GenBank): QRK03774.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-90a
Chemical type: Peptide from protein
Sequence: NAAISDYDY
Position: 4839-4847
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-90a
Chemical type: Peptide from protein
Sequence: NAAISDYDY
Position: 4839-4847
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NSP12-90b
Chemical type: Peptide from protein
Sequence: NAAITDYNY
Position: 4812-4820
Source molecule (GenBank): P0C6X6
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-90c
Chemical type: Peptide from protein
Sequence: DAAVKDFDF
Position: 4485-4493
Source molecule (GenBank): QEG03729.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-90d
Chemical type: Peptide from protein
Sequence: DAAIKDFDY
Position: 4515-4523
Source molecule (GenBank): QEG03783.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP7-5
Chemical type: Peptide from protein
Sequence: RVESSSKLWAQCVQL
Position: 3880-3894
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP7-5
Chemical type: Peptide from protein
Sequence: RVESSSKLWAQCVQL
Position: 3880-3894
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP7-11
Chemical type: Peptide from protein
Sequence: KMVSLLSVLLSMQGA
Position: 3910-3924
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP7-11
Chemical type: Peptide from protein
Sequence: KMVSLLSVLLSMQGA
Position: 3910-3924
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NSP7-15
Chemical type: Peptide from protein
Sequence: NKLCEEMLDNRATLQ
Position: 3928-3942
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP7-15
Chemical type: Peptide from protein
Sequence: NKLCEEMLDNRATLQ
Position: 3928-3942
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NSP12-88
Chemical type: Peptide from protein
Sequence: ELKHFFFAQDGNAAI
Position: 4828-4842
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-88
Chemical type: Peptide from protein
Sequence: ELKHFFFAQDGNAAI
Position: 4828-4842
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-90
Chemical type: Peptide from protein
Sequence: GNAAISDYDYYRYNL
Position: 4838-4852
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-90
Chemical type: Peptide from protein
Sequence: GNAAISDYDYYRYNL
Position: 4838-4852
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-102
Chemical type: Peptide from protein
Sequence: FNKWGKARLYYDSMS
Position: 4898-4912
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-102
Chemical type: Peptide from protein
Sequence: FNKWGKARLYYDSMS
Position: 4898-4912
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NSP12-171
Chemical type: Peptide from protein
Sequence: DGTLMIERFVSLAID
Position: 5243-5257
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-171
Chemical type: Peptide from protein
Sequence: DGTLMIERFVSLAID
Position: 5243-5257
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NSP13-79
Chemical type: Peptide from protein
Sequence: LRAKHYVYIGDPAQL
Position: 5715-5729
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP13-79
Chemical type: Peptide from protein
Sequence: LRAKHYVYIGDPAQL
Position: 5715-5729
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP13-118
Chemical type: Peptide from protein
Sequence: FTSLEIPRRNVATLQ
Position: 5911-5925
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP13-118
Chemical type: Peptide from protein
Sequence: FTSLEIPRRNVATLQ
Position: 5911-5925
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-166
Chemical type: Peptide from protein
Sequence: YVYLPYPDPSRILGA
Position: 5218-5232
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-166
Chemical type: Peptide from protein
Sequence: YVYLPYPDPSRILGA
Position: 5218-5232
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NSP12-166
Chemical type: Peptide from protein
Sequence: YVYLPYPDPSRILGA
Position: 5218-5232
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-84
Chemical type: Peptide from protein
Sequence: NKDFYDFAVSKGFFK
Position: 4808-4822
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-87
Chemical type: Peptide from protein
Sequence: EGSSVELKHFFFAQD
Position: 4823-4837
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-87
Chemical type: Peptide from protein
Sequence: EGSSVELKHFFFAQD
Position: 4823-4837
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-92
Chemical type: Peptide from protein
Sequence: YRYNLPTMCDIRQLL
Position: 4848-4862
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-92
Chemical type: Peptide from protein
Sequence: YRYNLPTMCDIRQLL
Position: 4848-4862
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-148
Chemical type: Peptide from protein
Sequence: DVDTDFVNEFYAYLR
Position: 5128-5142
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP12-148
Chemical type: Peptide from protein
Sequence: DVDTDFVNEFYAYLR
Position: 5128-5142
Source molecule (GenBank): QHD43415.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CoV-1 epitope 1
Chemical type: Peptide from protein
Sequence: KLWAQCVQL
Position: 3863-3871
Source molecule (GenBank): P59641.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CoV-1 epitope 1
Chemical type: Peptide from protein
Sequence: KLWAQCVQL
Position: 3863-3871
Source molecule (GenBank): P59641.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CoV-1 epitope 1
Chemical type: Peptide from protein
Sequence: KLWAQCVQL
Position: 3863-3871
Source molecule (GenBank): P59641.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CoV-1 epitope 1
Chemical type: Peptide from protein
Sequence: KLWAQCVQL
Position: 3863-3871
Source molecule (GenBank): P59641.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CoV-1 epitope 1
Chemical type: Peptide from protein
Sequence: KLWAQCVQL
Position: 3863-3871
Source molecule (GenBank): P59641.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CoV-1 epitope 2
Chemical type: Peptide from protein
Sequence: NAAISDYDY
Position: 4816-4824
Source molecule (GenBank): P59641.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CoV-1 epitope 2
Chemical type: Peptide from protein
Sequence: NAAISDYDY
Position: 4816-4824
Source molecule (GenBank): P59641.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MERS epitope
Chemical type: Peptide from protein
Sequence: NAAITDYNY
Position: 4825-4833
Source molecule (GenBank): AXP07343.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HKU1 epitope
Chemical type: Peptide from protein
Sequence: NAAITDYNY
Position: 4900-4908
Source molecule (GenBank): ADN03337.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated