Reference: Martine Bruley Rosset; Clara Ballerini; Sylvie Gregoire; Pat Metharom; Claude Carnaud; Pierre Aucouturier. "Breaking immune tolerance to the prion protein using prion protein peptides plus oligodeoxynucleotide-CpG in mice." Journal of immunology (Baltimore, Md. : 1950) (2004).

Epitope: PrP 98-127
Chemical type: Peptide from protein
Sequence: WNKPSKPKTNLKHVAGAAAAGAVVGGLG
Position: 98-125
Source molecule (GenBank): P04925.2
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: PrP 98-127
Chemical type: Peptide from protein
Sequence: WNKPSKPKTNLKHVAGAAAAGAVVGGLG
Position: 98-125
Source molecule (GenBank): P04925.2
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: PrP 98-127
Chemical type: Peptide from protein
Sequence: WNKPSKPKTNLKHVAGAAAAGAVVGGLG
Position: 98-125
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Negative
Quantitative measurement: 10.0
Host: F 6 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP 143-172
Chemical type: Peptide from protein
Sequence: DWEDRYYRENMYRYPNQVYYRPVDQYSN
Position: 143-170
Source molecule (GenBank): P04925.2
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: PrP 143-172
Chemical type: Peptide from protein
Sequence: DWEDRYYRENMYRYPNQVYYRPVDQYSN
Position: 143-170
Source molecule (GenBank): P04925.2
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: PrP 143-172
Chemical type: Peptide from protein
Sequence: DWEDRYYRENMYRYPNQVYYRPVDQYSN
Position: 143-170
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Positive
Quantitative measurement: 67.0
Host: F 6 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP 143-172
Chemical type: Peptide from protein
Sequence: DWEDRYYRENMYRYPNQVYYRPVDQYSN
Position: 143-170
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Negative
Host: F 6 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP 158-187
Chemical type: Peptide from protein
Sequence: NQVYYRPVDQYSNQNNFVHDCVNITIKQHT
Position: 158-187
Source molecule (GenBank): P04925.2
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: PrP 158-187
Chemical type: Peptide from protein
Sequence: NQVYYRPVDQYSNQNNFVHDCVNITIKQHT
Position: 158-187
Source molecule (GenBank): P04925.2
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: PrP 158-187
Chemical type: Peptide from protein
Sequence: NQVYYRPVDQYSNQNNFVHDCVNITIKQHT
Position: 158-187
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Positive
Quantitative measurement: 223.0
Host: F 6 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP 144-158
Chemical type: Peptide from protein
Sequence: WEDRYYRENMYRYPN
Position: 144-158
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Negative
Host: F 6 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP 148-162
Chemical type: Peptide from protein
Sequence: RYYRENMYRYPNQVYY
Position: 147-162
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Negative
Host: F 6 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP 152-166
Chemical type: Peptide from protein
Sequence: NMYRYPNQVYYRPVD
Position: 152-166
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Negative
Host: F 6 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP 168-182
Chemical type: Peptide from protein
Sequence: YSNQNNFVHDCVNIT
Position: 168-182
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Negative
Host: F 6 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP 172-186
Chemical type: Peptide from protein
Sequence: NNFVHDCVNITIKQH
Position: 172-186
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Negative
Host: F 6 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP 156-170
Chemical type: Peptide from protein
Sequence: YPNQVYYRPVDQYSN
Position: 156-170
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Positive
Host: F 6 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP 160-174
Chemical type: Peptide from protein
Sequence: VYYRPVDQYSNQNNF
Position: 160-174
Source molecule (GenBank): P04925.2
Assay category: TCell
Result: Positive
Host: F 6 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PrP 39-67
Chemical type: Peptide from protein
Sequence: YPGQGSPGGDRYPPQGGTWGQPHGGGT
Assay category: TCell
Result: Negative
Host: F 6 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo