Reference: Michelle So; Colleen M Elso; Eleonora Tresoldi; Miha Pakusch; Vimukthi Pathiraja; John M Wentworth; Leonard C Harrison; Balasubramanian Krishnamurthy; Helen E Thomas; Christine Rodda; Fergus J Cameron; Jacinta McMahon; Thomas W H Kay; Stuart I Mannering. "Proinsulin C-peptide is an autoantigen in people with type 1 diabetes." Proceedings of the National Academy of Sciences of the United States of America (2018).

Epitope: C-protein
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ
Position: 57-87
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  8-47 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C-protein
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ
Position: 57-87
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive-Low
Host:  12-61 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PI 50-59
Chemical type: Peptide from protein
Sequence: AGSLQPLALE
Position: 74-83
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone

Epitope: PI 50-59
Chemical type: Peptide from protein
Sequence: AGSLQPLALE
Position: 74-83
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone

Epitope: PI 50-58
Chemical type: Peptide from protein
Sequence: AGSLQPLAL
Position: 74-82
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 50-58
Chemical type: Peptide from protein
Sequence: AGSLQPLAL
Position: 74-82
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 52-62
Chemical type: Peptide from protein
Sequence: SLQPLALEGSL
Position: 76-86
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone

Epitope: PI 52-62
Chemical type: Peptide from protein
Sequence: SLQPLALEGSL
Position: 76-86
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 52-62
Chemical type: Peptide from protein
Sequence: SLQPLALEGSL
Position: 76-86
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 52-62
Chemical type: Peptide from protein
Sequence: SLQPLALEGSL
Position: 76-86
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone

Epitope: PI 52-62
Chemical type: Peptide from protein
Sequence: SLQPLALEGSL
Position: 76-86
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 41-49
Chemical type: Peptide from protein
Sequence: QVELGGGPG
Position: 65-73
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone

Epitope: PI 41-49
Chemical type: Peptide from protein
Sequence: QVELGGGPG
Position: 65-73
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: pancreas
Culture conditions: Cell Line / Clone

Epitope: PI 48-59
Chemical type: Peptide from protein
Sequence: PGAGSLQPLALE
Position: 72-83
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 48-59
Chemical type: Peptide from protein
Sequence: PGAGSLQPLALE
Position: 72-83
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 54-63
Chemical type: Peptide from protein
Sequence: QPLALEGSL
Position: 78-86
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 54-63
Chemical type: Peptide from protein
Sequence: QPLALEGSL
Position: 78-86
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 54-63
Chemical type: Peptide from protein
Sequence: QPLALEGSL
Position: 78-86
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 54-64
Chemical type: Peptide from protein
Sequence: QPLALEGSLQ
Position: 78-87
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 54-64
Chemical type: Peptide from protein
Sequence: QPLALEGSLQ
Position: 78-87
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 34-43
Chemical type: Peptide from protein
Sequence: AEDLQVGQVE
Position: 58-67
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 34-43
Chemical type: Peptide from protein
Sequence: AEDLQVGQVE
Position: 58-67
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 34-43
Chemical type: Peptide from protein
Sequence: AEDLQVGQVE
Position: 58-67
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 56-62
Chemical type: Peptide from protein
Sequence: LALEGSL
Position: 80-86
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 56-62
Chemical type: Peptide from protein
Sequence: LALEGSL
Position: 80-86
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 56-62
Chemical type: Peptide from protein
Sequence: LALEGSL
Position: 80-86
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 56-62
Chemical type: Peptide from protein
Sequence: LALEGSL
Position: 80-86
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 56-62
Chemical type: Peptide from protein
Sequence: LALEGSL
Position: 80-86
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 52-61
Chemical type: Peptide from protein
Sequence: SLQPLALEGS
Position: 76-85
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 52-61
Chemical type: Peptide from protein
Sequence: SLQPLALEGS
Position: 76-85
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 42-51
Chemical type: Peptide from protein
Sequence: VELGGGPGA
Position: 66-74
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 42-51
Chemical type: Peptide from protein
Sequence: VELGGGPGA
Position: 66-74
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 42-51
Chemical type: Peptide from protein
Sequence: VELGGGPGA
Position: 66-74
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 35-46
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVELGG
Position: 57-70
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 35-46
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVELGG
Position: 57-70
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 52-63
Chemical type: Peptide from protein
Sequence: SLQPLALEGSLQ
Position: 76-87
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 52-63
Chemical type: Peptide from protein
Sequence: SLQPLALEGSLQ
Position: 76-87
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 49-58
Chemical type: Peptide from protein
Sequence: GAGSLQPLAL
Position: 73-82
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 49-58
Chemical type: Peptide from protein
Sequence: GAGSLQPLAL
Position: 73-82
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PI 49-58
Chemical type: Peptide from protein
Sequence: GAGSLQPLAL
Position: 73-82
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  12-36 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone