Reference: Derin B Keskin; Annabelle J Anandappa; Jing Sun; Itay Tirosh; Nathan D Mathewson; Shuqiang Li; Giacomo Oliveira; Anita Giobbie-Hurder; Kristen Felt; Evisa Gjini; Sachet A Shukla; Zhuting Hu; Letitia Li; Phuong M Le; Rosa L Allesøe; Alyssa R Richman; Monika S Kowalczyk; Sara Abdelrahman; Jack E Geduldig; Sarah Charbonneau; Kristine Pelton; J Bryan Iorgulescu; Liudmila Elagina; Wandi Zhang; Oriol Olive; Christine McCluskey; Lars R Olsen; Jonathan Stevens; William J Lane; Andres M Salazar; Heather Daley; Patrick Y Wen; E Antonio Chiocca; Maegan Harden; Niall J Lennon; Stacey Gabriel; Gad Getz; Eric S Lander; Aviv Regev; Jerome Ritz; Donna Neuberg; Scott J Rodig; Keith L Ligon; Mario L Suvà; Kai W Wucherpfennig; Nir Hacohen; Edward F Fritsch; Kenneth J Livak; Patrick A Ott; Catherine J Wu; David A Reardon. "Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial." Nature (2019).

Epitope: ARHGAP35 MUT (ASP34)
Chemical type: Peptide, no natural source
Sequence: HNLDLAEKDFMVNTV
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: ARHGAP35 MUT (ASP34)
Chemical type: Peptide, no natural source
Sequence: HNLDLAEKDFMVNTV
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GPC1 MUT
Chemical type: Peptide, no natural source
Sequence: NRSHAKLETALRDSS
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ARHGAP35 MUT (ASP35)
Chemical type: Peptide, no natural source
Sequence: LAEKDFMVNTVAGAMK
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: ARHGAP35 MUT (ASP35)
Chemical type: Peptide, no natural source
Sequence: LAEKDFMVNTVAGAMK
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ARHGAP35 WT
Chemical type: Peptide from protein
Sequence: LAEKDFTVNTVAGAMK
Position: 1307-1322
Source molecule (GenBank): Q9NRY4.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: ARHGAP35 WT
Chemical type: Peptide from protein
Sequence: LAEKDFTVNTVAGAMK
Position: 1307-1322
Source molecule (GenBank): Q9NRY4.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ARHGAP35 WT
Chemical type: Peptide from protein
Sequence: HNLDLAEKDFTVNTV
Position: 1303-1317
Source molecule (GenBank): Q9NRY4.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: ARHGAP35 WT
Chemical type: Peptide from protein
Sequence: HNLDLAEKDFTVNTV
Position: 1303-1317
Source molecule (GenBank): Q9NRY4.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GPC1 MUT
Chemical type: Peptide, no natural source
Sequence: HAKLETALRDSSRVL
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GPC1 WT
Chemical type: Peptide from protein
Sequence: EENLANRSHAELETAL
Position: 74-89
Source molecule (GenBank): P35052.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GPC1 WT
Chemical type: Peptide from protein
Sequence: NRSHAELETALRDSS
Position: 79-93
Source molecule (GenBank): P35052.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GPC1 WT
Chemical type: Peptide from protein
Sequence: HAELETALRDSSRVL
Position: 82-96
Source molecule (GenBank): P35052.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GPC1 WT
Chemical type: Peptide from protein
Sequence: ANRSHAELETALRDSS
Position: 78-93
Source molecule (GenBank): P35052.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SLX4 MUT
Chemical type: Peptide, no natural source
Sequence: TTAATHREK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ARHGAP35 MUT (EPTA12A)
Chemical type: Peptide, no natural source
Sequence: MVNTVAGAMK
Assay category: TCell
Result: Positive
MHC allele types: 215 230 196 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: ARHGAP35 MUT (EPTA12A)
Chemical type: Peptide, no natural source
Sequence: MVNTVAGAMK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SLX4 WT
Chemical type: Peptide from protein
Sequence: TTAATRREK
Position: 1809-1817
Source molecule (GenBank): Q8IY92.3
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ARHGAP35 WT
Chemical type: Peptide from protein
Sequence: TVNTVAGAMK
Position: 1313-1322
Source molecule (GenBank): Q9NRY4.3
Assay category: TCell
Result: Negative
MHC allele types: 215 230 196 197
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: ARHGAP35 WT
Chemical type: Peptide from protein
Sequence: TVNTVAGAMK
Position: 1313-1322
Source molecule (GenBank): Q9NRY4.3
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: COX18 MUT
Chemical type: Peptide, no natural source
Sequence: SSFMGLSQNLLLRSP
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SVEP1 MUT
Chemical type: Peptide, no natural source
Sequence: GPPAHVENAIARGIH
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SVEP1 MUT
Chemical type: Peptide, no natural source
Sequence: HVENAIARGIHYQYGD
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: COX18 WT
Chemical type: Peptide from protein
Sequence: SSFVGLSQNLLLRSP
Position: 285-299
Source molecule (GenBank): Q8N8Q8.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: COX18 WT
Chemical type: Peptide from protein
Sequence: GLSQNLLLRSPGFRQL
Position: 289-304
Source molecule (GenBank): Q8N8Q8.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SHANK2 MUT
Chemical type: Peptide, no natural source
Sequence: GEIPLHRSDRVKVLSI
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SHANK2 MUT
Chemical type: Peptide, no natural source
Sequence: PQVDGEIPLHRSDRV
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SHANK2 MUT
Chemical type: Peptide, no natural source
Sequence: GEIPLHRSDRVKVLS
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SVEP1 WT
Chemical type: Peptide from protein
Sequence: GPPAHVENAIARGVH
Position: 3417-3431
Source molecule (GenBank): Q4LDE5.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SVEP1 WT
Chemical type: Peptide from protein
Sequence: HVENAIARGVHYQYGD
Position: 3421-3436
Source molecule (GenBank): Q4LDE5.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SHANK2 WT
Chemical type: Peptide from protein
Sequence: PQVDGEIPLHRGDRV
Position: 160-174
Source molecule (GenBank): Q9UPX8.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: SHANK2 WT
Chemical type: Peptide from protein
Sequence: GEIPLHRGDRVKVLS
Position: 164-178
Source molecule (GenBank): Q9UPX8.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated