Reference: Regina S Salvat; Yoonjoo Choi; Alexandra Bishop; Chris Bailey-Kellogg; Karl E Griswold. "Protein deimmunization via structure-based design enables efficient epitope deletion at high mutational loads." Biotechnology and bioengineering (2015).

Epitope: P99beta S257+R261+I262+S264
Chemical type: Peptide from protein
Sequence: ALAQSRYWRIGSMYQGL
Position: 273-289
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 41800.0

Epitope: P99beta S257+R261+I262+S264
Chemical type: Peptide from protein
Sequence: ALAQSRYWRIGSMYQGL
Position: 273-289
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 260.0

Epitope: P99beta S257+R261+I262+S264
Chemical type: Peptide from protein
Sequence: ALAQSRYWRIGSMYQGL
Position: 273-289
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 1790.0

Epitope: P99beta S257+R261+I262+S264
Chemical type: Peptide from protein
Sequence: ALAQSRYWRIGSMYQGL
Position: 273-289
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 850.0

Epitope: P99beta L A13+N14+T17
Chemical type: Peptide from protein
Sequence: EKQLAEVVANTITPLMK
Position: 25-41
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 156000.0

Epitope: P99beta L A13+N14+T17
Chemical type: Peptide from protein
Sequence: EKQLAEVVANTITPLMK
Position: 25-41
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 15950.0

Epitope: P99beta L A13+N14+T17
Chemical type: Peptide from protein
Sequence: EKQLAEVVANTITPLMK
Position: 25-41
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 620.0

Epitope: P99beta L A13+N14+T17
Chemical type: Peptide from protein
Sequence: EKQLAEVVANTITPLMK
Position: 25-41
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 7400.0

Epitope: P99beta R210+M215
Chemical type: Peptide from protein
Sequence: AVRVSPGMLDAQAYGVK
Position: 228-244
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta R210+M215
Chemical type: Peptide from protein
Sequence: AVRVSPGMLDAQAYGVK
Position: 228-244
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta R210+M215
Chemical type: Peptide from protein
Sequence: AVRVSPGMLDAQAYGVK
Position: 228-244
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 51100.0

Epitope: P99beta R210+M215
Chemical type: Peptide from protein
Sequence: AVRVSPGMLDAQAYGVK
Position: 228-244
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta Q102+R105
Chemical type: Peptide from protein
Sequence: GKQWQGIRMLDLATYT
Position: 118-133
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 220000.0

Epitope: P99beta Q102+R105
Chemical type: Peptide from protein
Sequence: GKQWQGIRMLDLATYT
Position: 118-133
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta Q102+R105
Chemical type: Peptide from protein
Sequence: GKQWQGIRMLDLATYT
Position: 118-133
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 10700.0

Epitope: P99beta Q102+R105
Chemical type: Peptide from protein
Sequence: GKQWQGIRMLDLATYT
Position: 118-133
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 96300.0

Epitope: P99beta V25
Chemical type: Peptide from protein
Sequence: ITPLMKAQSVPGMAVA
Position: 36-51
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 5610.0

Epitope: P99beta V25
Chemical type: Peptide from protein
Sequence: ITPLMKAQSVPGMAVA
Position: 36-51
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 3150.0

Epitope: P99beta V25
Chemical type: Peptide from protein
Sequence: ITPLMKAQSVPGMAVA
Position: 36-51
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 1700.0

Epitope: P99beta V25
Chemical type: Peptide from protein
Sequence: ITPLMKAQSVPGMAVA
Position: 36-51
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 42910.0

Epitope: P99beta F43
Chemical type: Peptide from protein
Sequence: KPHYYTFGKADIAAN
Position: 57-71
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 790.0

Epitope: P99beta F43
Chemical type: Peptide from protein
Sequence: KPHYYTFGKADIAAN
Position: 57-71
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 199000.0

Epitope: P99beta F43
Chemical type: Peptide from protein
Sequence: KPHYYTFGKADIAAN
Position: 57-71
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta F43
Chemical type: Peptide from protein
Sequence: KPHYYTFGKADIAAN
Position: 57-71
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta M235+V243
Chemical type: Peptide from protein
Sequence: ANWVMANMAPENVADASL
Position: 251-268
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 1710.0

Epitope: P99beta M235+V243
Chemical type: Peptide from protein
Sequence: ANWVMANMAPENVADASL
Position: 251-268
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 48000.0

Epitope: P99beta M235+V243
Chemical type: Peptide from protein
Sequence: ANWVMANMAPENVADASL
Position: 251-268
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta M235+V243
Chemical type: Peptide from protein
Sequence: ANWVMANMAPENVADASL
Position: 251-268
Source molecule (GenBank): P05364.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 4790.0

Epitope: P99beta S257Q+R261Q
Chemical type: Peptide, no natural source
Sequence: ALAQQRYWQIGSMYQGL
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 6080.0

Epitope: P99beta S257Q+R261Q
Chemical type: Peptide, no natural source
Sequence: ALAQQRYWQIGSMYQGL
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 640.0

Epitope: P99beta S257Q+R261Q
Chemical type: Peptide, no natural source
Sequence: ALAQQRYWQIGSMYQGL
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 3410.0

Epitope: P99beta S257Q+R261Q
Chemical type: Peptide, no natural source
Sequence: ALAQQRYWQIGSMYQGL
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 2830.0

Epitope: P99beta R261Q
Chemical type: Peptide, no natural source
Sequence: ALAQSRYWQIGSMYQGL
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 35800.0

Epitope: P99beta R261Q
Chemical type: Peptide, no natural source
Sequence: ALAQSRYWQIGSMYQGL
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 5120.0

Epitope: P99beta R261Q
Chemical type: Peptide, no natural source
Sequence: ALAQSRYWQIGSMYQGL
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 1720.0

Epitope: P99beta R261Q
Chemical type: Peptide, no natural source
Sequence: ALAQSRYWQIGSMYQGL
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 8080.0

Epitope: P99beta I262A
Chemical type: Peptide, no natural source
Sequence: ALAQSRYWRAGSMYQGL
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta I262A
Chemical type: Peptide, no natural source
Sequence: ALAQSRYWRAGSMYQGL
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 730.0

Epitope: P99beta I262A
Chemical type: Peptide, no natural source
Sequence: ALAQSRYWRAGSMYQGL
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 10300.0

Epitope: P99beta I262A
Chemical type: Peptide, no natural source
Sequence: ALAQSRYWRAGSMYQGL
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta S264E
Chemical type: Peptide, no natural source
Sequence: ALAQSRYWRIGEMYQGL
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta S264E
Chemical type: Peptide, no natural source
Sequence: ALAQSRYWRIGEMYQGL
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 86500.0

Epitope: P99beta S264E
Chemical type: Peptide, no natural source
Sequence: ALAQSRYWRIGEMYQGL
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 52900.0

Epitope: P99beta S264E
Chemical type: Peptide, no natural source
Sequence: ALAQSRYWRIGEMYQGL
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 1800.0

Epitope: P99beta M215Q
Chemical type: Peptide, no natural source
Sequence: AVRVSPGQLDAQAYGVK
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta M215Q
Chemical type: Peptide, no natural source
Sequence: AVRVSPGQLDAQAYGVK
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta M215Q
Chemical type: Peptide, no natural source
Sequence: AVRVSPGQLDAQAYGVK
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta M215Q
Chemical type: Peptide, no natural source
Sequence: AVRVSPGQLDAQAYGVK
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99betaN14R+T17Q
Chemical type: Peptide, no natural source
Sequence: EKQLAEVVARTIQPLMK
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 56000.0

Epitope: P99betaN14R+T17Q
Chemical type: Peptide, no natural source
Sequence: EKQLAEVVARTIQPLMK
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99betaN14R+T17Q
Chemical type: Peptide, no natural source
Sequence: EKQLAEVVARTIQPLMK
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 1410.0

Epitope: P99betaN14R+T17Q
Chemical type: Peptide, no natural source
Sequence: EKQLAEVVARTIQPLMK
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 1050.0

Epitope: P99beta Q102D
Chemical type: Peptide, no natural source
Sequence: GKQWDGIRMLDLATYT
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta Q102D
Chemical type: Peptide, no natural source
Sequence: GKQWDGIRMLDLATYT
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 11800.0

Epitope: P99beta Q102D
Chemical type: Peptide, no natural source
Sequence: GKQWDGIRMLDLATYT
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta Q102D
Chemical type: Peptide, no natural source
Sequence: GKQWDGIRMLDLATYT
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 80400.0

Epitope: P99beta V25I
Chemical type: Peptide, no natural source
Sequence: ITPLMKAQSIPGMAVA
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 4460.0

Epitope: P99beta V25I
Chemical type: Peptide, no natural source
Sequence: ITPLMKAQSIPGMAVA
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 4290.0

Epitope: P99beta V25I
Chemical type: Peptide, no natural source
Sequence: ITPLMKAQSIPGMAVA
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 21300.0

Epitope: P99beta V25I
Chemical type: Peptide, no natural source
Sequence: ITPLMKAQSIPGMAVA
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 2160.0

Epitope: P99beta F43W
Chemical type: Peptide, no natural source
Sequence: KPHYYTWGKADIAAN
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 380.0

Epitope: P99beta F43W
Chemical type: Peptide, no natural source
Sequence: KPHYYTWGKADIAAN
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 32600.0

Epitope: P99beta F43W
Chemical type: Peptide, no natural source
Sequence: KPHYYTWGKADIAAN
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta F43W
Chemical type: Peptide, no natural source
Sequence: KPHYYTWGKADIAAN
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta M235Q
Chemical type: Peptide, no natural source
Sequence: MANWVQANMAPENVA
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta M235Q
Chemical type: Peptide, no natural source
Sequence: MANWVQANMAPENVA
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta M235Q
Chemical type: Peptide, no natural source
Sequence: MANWVQANMAPENVA
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta M235Q
Chemical type: Peptide, no natural source
Sequence: MANWVQANMAPENVA
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta N281K
Chemical type: Peptide, no natural source
Sequence: MLNWPVEAKTVVEGSD
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta N281K
Chemical type: Peptide, no natural source
Sequence: MLNWPVEAKTVVEGSD
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta N281K
Chemical type: Peptide, no natural source
Sequence: MLNWPVEAKTVVEGSD
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 151000.0

Epitope: P99beta N281K
Chemical type: Peptide, no natural source
Sequence: MLNWPVEAKTVVEGSD
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta L149Q
Chemical type: Peptide, no natural source
Sequence: TTRQYANASIGLFGA
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 25100.0

Epitope: P99beta L149Q
Chemical type: Peptide, no natural source
Sequence: TTRQYANASIGLFGA
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 11800.0

Epitope: P99beta L149Q
Chemical type: Peptide, no natural source
Sequence: TTRQYANASIGLFGA
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 146000.0

Epitope: P99beta L149Q
Chemical type: Peptide, no natural source
Sequence: TTRQYANASIGLFGA
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 11800.0

Epitope: P99beta V243L
Chemical type: Peptide, no natural source
Sequence: WVMANMAPENLADASL
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 149000.0

Epitope: P99beta V243L
Chemical type: Peptide, no natural source
Sequence: WVMANMAPENLADASL
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: P99beta V243L
Chemical type: Peptide, no natural source
Sequence: WVMANMAPENLADASL
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 149000.0

Epitope: P99beta V243L
Chemical type: Peptide, no natural source
Sequence: WVMANMAPENLADASL
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0