Reference: Sen Ma; Doudou Zhang; Qiwei Wang; Linjing Zhu; Xilin Wu; Sheng Ye; Yaxin Wang. "Structure defining of ultrapotent neutralizing nanobodies against MERS-CoV with novel epitopes on receptor binding domain." PLoS pathogens (2024).

Epitope: Epitope of nanobody Nb14 on MERS-CoV RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G391, T392, V484, P485, H486, N487, L488, T489, I491, T492, K493, L495, K496, T533, V534, W535, E536, D539, A562, M563
Source molecule (GenBank): AFS88936.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb14 on MERS-CoV RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G391, T392, V484, P485, H486, N487, L488, T489, I491, T492, K493, L495, K496, T533, V534, W535, E536, D539, A562, M563
Source molecule (GenBank): AFS88936.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: F 2-3 years

Epitope: Epitope of nanobody Nb14 on MERS-CoV RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G391, T392, V484, P485, H486, N487, L488, T489, I491, T492, K493, L495, K496, T533, V534, W535, E536, D539, A562, M563
Source molecule (GenBank): AFS88936.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.99
Host: F 2-3 years

Epitope: Epitope of nanobody Nb14 on MERS-CoV RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G391, T392, V484, P485, H486, N487, L488, T489, I491, T492, K493, L495, K496, T533, V534, W535, E536, D539, A562, M563
Source molecule (GenBank): AFS88936.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb14 on MERS-CoV RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G391, T392, V484, P485, H486, N487, L488, T489, I491, T492, K493, L495, K496, T533, V534, W535, E536, D539, A562, M563
Source molecule (GenBank): AFS88936.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb14 on MERS-CoV RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G391, T392, V484, P485, H486, N487, L488, T489, I491, T492, K493, L495, K496, T533, V534, W535, E536, D539, A562, M563
Source molecule (GenBank): AFS88936.1
Assay category: BCell
Result: Positive
Quantitative measurement: 934000.0
Host: F 2-3 years

Epitope: Epitope of nanobody Nb14 on MERS-CoV RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G391, T392, V484, P485, H486, N487, L488, T489, I491, T492, K493, L495, K496, T533, V534, W535, E536, D539, A562, M563
Source molecule (GenBank): AFS88936.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00000010
Host: F 2-3 years

Epitope: Epitope of nanobody Nb14 on MERS-CoV RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: G391, T392, V484, P485, H486, N487, L488, T489, I491, T492, K493, L495, K496, T533, V534, W535, E536, D539, A562, M563
Source molecule (GenBank): AFS88936.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb9 on MERS-CoV RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: S465, Q466, F467, K470, F473, R505, L507, S508, T512, E513, V514, P515, Q516, L517, V518, N519, A520, P525, L545, L548, E549, G550
Source molecule (GenBank): AFS88936.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: F 2-3 years

Epitope: Epitope of nanobody Nb9 on MERS-CoV RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: S465, Q466, F467, K470, F473, R505, L507, S508, T512, E513, V514, P515, Q516, L517, V518, N519, A520, P525, L545, L548, E549, G550
Source molecule (GenBank): AFS88936.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00000010
Host: F 2-3 years

Epitope: Epitope of nanobody Nb9 on MERS-CoV RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: S465, Q466, F467, K470, F473, R505, L507, S508, T512, E513, V514, P515, Q516, L517, V518, N519, A520, P525, L545, L548, E549, G550
Source molecule (GenBank): AFS88936.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb9 on MERS-CoV RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: S465, Q466, F467, K470, F473, R505, L507, S508, T512, E513, V514, P515, Q516, L517, V518, N519, A520, P525, L545, L548, E549, G550
Source molecule (GenBank): AFS88936.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb9 on MERS-CoV RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: S465, Q466, F467, K470, F473, R505, L507, S508, T512, E513, V514, P515, Q516, L517, V518, N519, A520, P525, L545, L548, E549, G550
Source molecule (GenBank): AFS88936.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb9 on MERS-CoV RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: S465, Q466, F467, K470, F473, R505, L507, S508, T512, E513, V514, P515, Q516, L517, V518, N519, A520, P525, L545, L548, E549, G550
Source molecule (GenBank): AFS88936.1
Assay category: BCell
Result: Positive
Host: F 2-3 years

Epitope: Epitope of nanobody Nb9 on MERS-CoV RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: S465, Q466, F467, K470, F473, R505, L507, S508, T512, E513, V514, P515, Q516, L517, V518, N519, A520, P525, L545, L548, E549, G550
Source molecule (GenBank): AFS88936.1
Assay category: BCell
Result: Positive
Quantitative measurement: 388000.0
Host: F 2-3 years

Epitope: Epitope of nanobody Nb9 on MERS-CoV RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: S465, Q466, F467, K470, F473, R505, L507, S508, T512, E513, V514, P515, Q516, L517, V518, N519, A520, P525, L545, L548, E549, G550
Source molecule (GenBank): AFS88936.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.76
Host: F 2-3 years