Reference: Patrick A Ott; Siwen Hu-Lieskovan; Bartosz Chmielowski; Ramaswamy Govindan; Aung Naing; Nina Bhardwaj; Kim Margolin; Mark M Awad; Matthew D Hellmann; Jessica J Lin; Terence Friedlander; Meghan E Bushway; Kristen N Balogh; Tracey E Sciuto; Victoria Kohler; Samantha J Turnbull; Rana Besada; Riley R Curran; Benjamin Trapp; Julian Scherer; Asaf Poran; Dewi Harjanto; Dominik Barthelme; Ying Sonia Ting; Jesse Z Dong; Yvonne Ware; Yuting Huang; Zhengping Huang; Amy Wanamaker; Lisa D Cleary; Melissa A Moles; Kelledy Manson; Joel Greshock; Zakaria S Khondker; Ed Fritsch; Michael S Rooney; Mark DeMario; Richard B Gaynor; Lakshmi Srinivasan. "A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer." Cell (2020).

Epitope: M1-IM01-ASP0037
Chemical type: Peptide, no natural source
Sequence: RVYPETYEWARKMAV
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M1-IM02-ASP0033
Chemical type: Peptide, no natural source
Sequence: FPKPFESSFSIGAE
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M1-IM24-ASP0047
Chemical type: Peptide, no natural source
Sequence: FQVKDIPYFQTINI
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M2-IM02-ASP0017
Chemical type: Peptide, no natural source
Sequence: RVIHIKTSTVPPLLRK
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M2-IM27-ASP0035
Chemical type: Peptide, no natural source
Sequence: DAKEFTFIDLVPGRK
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M4-IM16-ASP0028
Chemical type: Peptide, no natural source
Sequence: VAFTSQWHSTSSPVSM
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M4-IM22-ASP0048
Chemical type: Peptide, no natural source
Sequence: STTASVAQKRKSDGS
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M5-IM34.ASP0032
Chemical type: Peptide, no natural source
Sequence: LCRRPSLLRQPLPTR
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M5-IM15.ASP0062
Chemical type: Peptide, no natural source
Sequence: RRPSLLRQPLPTRCD
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1-IM29-ASP0051
Chemical type: Peptide, no natural source
Sequence: AMGLGTPSEAIDITA
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1-IM20-ASP0004
Chemical type: Peptide, no natural source
Sequence: GGGRKVRLMKEVMEH
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1-IM25-ASP0012
Chemical type: Peptide, no natural source
Sequence: AAPLAGFVYGLPISRL
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M1-IM01-ASP0037 Wt
Chemical type: Peptide from protein
Sequence: RVHPETYEWARKMAV
Position: 1057-1071
Source molecule (GenBank): Q7KZ85.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M1-IM02-ASP0033 Wt
Chemical type: Peptide from protein
Sequence: FPKPFESSSSIGAE
Position: 1179-1192
Source molecule (GenBank): Q15154.5
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M1-IM24-ASP0047 Wt
Chemical type: Peptide from protein
Sequence: FQVKDIPYFQTKNI
Position: 1437-1450
Source molecule (GenBank): Q6R327.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M2-IM02-ASP0017 Wt
Chemical type: Peptide from protein
Sequence: RVIHIKTSTVPPSLRK
Position: 653-668
Source molecule (GenBank): Q99941.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M2-IM27-ASP0035 Wt
Chemical type: Peptide from protein
Sequence: DAKEFTFTDLVPGRK
Position: 516-530
Source molecule (GenBank): P23467.3
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M4-IM16-ASP0028 Wt
Chemical type: Peptide from protein
Sequence: VAFTPQWHSTSSPVSM
Position: 4760-4775
Source molecule (GenBank): Q8WXI7.3
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M4-IM22-ASP0048 Wt
Chemical type: Peptide from protein
Sequence: STTASVARKRKSDGS
Position: 566-580
Source molecule (GenBank): Q8IZT6.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M5-IM34.ASP0032 Wt
Chemical type: Peptide from protein
Sequence: LCRRPSLLRQPPPTR
Position: 510-524
Source molecule (GenBank): Q8WUG5.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M5-IM15.ASP0062 Wt
Chemical type: Peptide from protein
Sequence: RRPSLLRQPPPTRCD
Position: 512-526
Source molecule (GenBank): Q8WUG5.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1-IM29-ASP0051 Wt
Chemical type: Peptide from protein
Sequence: AMGLGTPSEAIEITA
Position: 2620-2634
Source molecule (GenBank): O95359.3
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1-IM20-ASP0004 Wt
Chemical type: Peptide from protein
Sequence: GGGQKVRLMKEVMEH
Position: 85-99
Source molecule (GenBank): O00469.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L1-IM25-ASP0012 Wt
Chemical type: Peptide from protein
Sequence: AAPLAGFGYGLPISRL
Position: 318-333
Source molecule (GenBank): Q15120.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo