Reference: Michele A Kutzler; Chuanhai Cao; Yun Bai; Huiqin Dong; Philip Y Choe; Vera Saulino; Laura McLaughlin; Alex Whelan; Andrew Y Choo; David B Weiner; Kenneth E Ugen. "Mapping of immune responses following wild-type and mutant ABeta42 plasmid or peptide vaccination in different mouse haplotypes and HLA Class II transgenic mice." Vaccine (2006).

Epitope: Abeta 1-42
Chemical type: Peptide from protein
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Position: 1-42
Source molecule (GenBank): 1IYT_A
Assay category: BCell
Result: Positive
Host:  8-12 weeks

Epitope: Abeta 1-42
Chemical type: Peptide from protein
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Position: 1-42
Source molecule (GenBank): 1IYT_A
Assay category: BCell
Result: Positive-Low
Host:  8-12 weeks

Epitope: Abeta 1-10
Chemical type: Peptide from protein
Sequence: DAEFRHDSGY
Position: 1-10
Source molecule (GenBank): 1IYT_A
Assay category: BCell
Result: Positive-High
Host:  8-12 weeks

Epitope: A beta 6-15
Chemical type: Peptide from protein
Sequence: DSGYEVHHQK
Position: 7-16
Source molecule (GenBank): 1IYT_A
Assay category: BCell
Result: Negative
Host:  8-12 weeks

Epitope: A beta 11-20
Chemical type: Peptide from protein
Sequence: EVHHQKLVFF
Position: 11-20
Source molecule (GenBank): 1IYT_A
Assay category: BCell
Result: Negative
Host:  8-12 weeks

Epitope: Abeta 17-40
Chemical type: Peptide from protein
Sequence: VFFAEDVGSNKGAIIGLMVGGVVIA
Position: 18-42
Source molecule (GenBank): 1IYT_A
Assay category: BCell
Result: Negative
Host:  8-12 weeks

Epitope: Abeta 1-43
Chemical type: Peptide from protein
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIAT
Position: 672-714
Source molecule (GenBank): P05067.3
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Abeta 1-43
Chemical type: Peptide from protein
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIAT
Position: 672-714
Source molecule (GenBank): P05067.3
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Abeta 1-43
Chemical type: Peptide from protein
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIAT
Position: 672-714
Source molecule (GenBank): P05067.3
Assay category: TCell
Result: Positive-High
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Abeta 10-20
Chemical type: Peptide from protein
Sequence: YEVHHQKLVFF
Position: 10-20
Source molecule (GenBank): 1IYT_A
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Abeta 12-28
Chemical type: Peptide from protein
Sequence: VHHQKLVFFAEDVGSNK
Position: 12-28
Source molecule (GenBank): 1IYT_A
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Abeta 29-40
Chemical type: Peptide from protein
Sequence: GAIIGLMVGGVVIAT
Position: 700-714
Source molecule (GenBank): P05067.3
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Abeta 1-28
Chemical type: Peptide from protein
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNK
Position: 1-28
Source molecule (GenBank): 1IYT_A
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Abeta 1-28
Chemical type: Peptide from protein
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNK
Position: 1-28
Source molecule (GenBank): 1IYT_A
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Abeta 1-28
Chemical type: Peptide from protein
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNK
Position: 1-28
Source molecule (GenBank): 1IYT_A
Assay category: TCell
Result: Positive-High
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Abeta 17-41
Chemical type: Peptide from protein
Sequence: LVFFAEDVGSNKGAIIGLMVGGVVI
Position: 17-41
Source molecule (GenBank): 1IYT_A
Assay category: TCell
Result: Positive-Low
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Abeta 17-41
Chemical type: Peptide from protein
Sequence: LVFFAEDVGSNKGAIIGLMVGGVVI
Position: 17-41
Source molecule (GenBank): 1IYT_A
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Abeta 17-41
Chemical type: Peptide from protein
Sequence: LVFFAEDVGSNKGAIIGLMVGGVVI
Position: 17-41
Source molecule (GenBank): 1IYT_A
Assay category: TCell
Result: Positive-Low
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo