Reference: R M Schulz; M Hawa; R D Leslie; F Sinigaglia; N Passini; L Rogge; J K Picard; M Londei. "Proliferative responses to selected peptides of IA-2 in identical twins discordant for Type 1 diabetes." Diabetes/metabolism research and reviews (2000).

Epitope: Peptide 5
Chemical type: Peptide from protein
Sequence: PSLSYEPALLQPY
Position: 197-209
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-41 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 5
Chemical type: Peptide from protein
Sequence: PSLSYEPALLQPY
Position: 197-209
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Negative
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 5
Chemical type: Peptide from protein
Sequence: PSLSYEPALLQPY
Position: 197-209
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 5
Chemical type: Peptide from protein
Sequence: PSLSYEPALLQPY
Position: 197-209
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: Peptide 10
Chemical type: Peptide from protein
Sequence: LEILAEHVHMSSG
Position: 490-502
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 10
Chemical type: Peptide from protein
Sequence: LEILAEHVHMSSG
Position: 490-502
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 10
Chemical type: Peptide from protein
Sequence: LEILAEHVHMSSG
Position: 490-502
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-41 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 10
Chemical type: Peptide from protein
Sequence: LEILAEHVHMSSG
Position: 490-502
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: Peptide 11
Chemical type: Peptide from protein
Sequence: GSFINISVVGPAL
Position: 502-514
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-41 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 11
Chemical type: Peptide from protein
Sequence: GSFINISVVGPAL
Position: 502-514
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 11
Chemical type: Peptide from protein
Sequence: GSFINISVVGPAL
Position: 502-514
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 11
Chemical type: Peptide from protein
Sequence: GSFINISVVGPAL
Position: 502-514
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 700.0

Epitope: Peptide 16
Chemical type: Peptide from protein
Sequence: RSVLLTLVALAGV
Position: 575-587
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 16
Chemical type: Peptide from protein
Sequence: RSVLLTLVALAGV
Position: 575-587
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 16
Chemical type: Peptide from protein
Sequence: RSVLLTLVALAGV
Position: 575-587
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-41 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 16
Chemical type: Peptide from protein
Sequence: RSVLLTLVALAGV
Position: 575-587
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: Peptide 19
Chemical type: Peptide from protein
Sequence: CAYQAEPNTCATA
Position: 717-729
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 19
Chemical type: Peptide from protein
Sequence: CAYQAEPNTCATA
Position: 717-729
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 19
Chemical type: Peptide from protein
Sequence: CAYQAEPNTCATA
Position: 717-729
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-41 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 19
Chemical type: Peptide from protein
Sequence: CAYQAEPNTCATA
Position: 717-729
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 500.0

Epitope: Peptide 21
Chemical type: Peptide from protein
Sequence: PAYIATQGPLSHT
Position: 778-790
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-41 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 21
Chemical type: Peptide from protein
Sequence: PAYIATQGPLSHT
Position: 778-790
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 21
Chemical type: Peptide from protein
Sequence: PAYIATQGPLSHT
Position: 778-790
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 21
Chemical type: Peptide from protein
Sequence: PAYIATQGPLSHT
Position: 778-790
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 150.0

Epitope: Peptide 25
Chemical type: Peptide from protein
Sequence: SLYHVYEVNLVSE
Position: 830-842
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 25
Chemical type: Peptide from protein
Sequence: SLYHVYEVNLVSE
Position: 830-842
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-41 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 25
Chemical type: Peptide from protein
Sequence: SLYHVYEVNLVSE
Position: 830-842
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 25
Chemical type: Peptide from protein
Sequence: SLYHVYEVNLVSE
Position: 830-842
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2000.0

Epitope: Peptide 30
Chemical type: Peptide from protein
Sequence: TYILIDMVLNRMA
Position: 918-930
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 30
Chemical type: Peptide from protein
Sequence: TYILIDMVLNRMA
Position: 918-930
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 30
Chemical type: Peptide from protein
Sequence: TYILIDMVLNRMA
Position: 918-930
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-41 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 30
Chemical type: Peptide from protein
Sequence: TYILIDMVLNRMA
Position: 918-930
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10000.0

Epitope: Peptide 32
Chemical type: Peptide from protein
Sequence: DQFEFALTAVAEE
Position: 957-969
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 32
Chemical type: Peptide from protein
Sequence: DQFEFALTAVAEE
Position: 957-969
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-64 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 32
Chemical type: Peptide from protein
Sequence: DQFEFALTAVAEE
Position: 957-969
Source molecule (GenBank): NP_002837.1
Assay category: TCell
Result: Positive
Host:  6-41 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 32
Chemical type: Peptide from protein
Sequence: DQFEFALTAVAEE
Position: 957-969
Source molecule (GenBank): NP_002837.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 600.0