Reference: Carl U Bialucha; Scott D Collins; Xiao Li; Parmita Saxena; Xiamei Zhang; Clemens Dürr; Bruno Lafont; Pierric Prieur; Yeonju Shim; Rebecca Mosher; David Lee; Lance Ostrom; Tiancen Hu; Sanela Bilic; Ivana Liric Rajlic; Vladimir Capka; Wei Jiang; Joel P Wagner; GiNell Elliott; Artur Veloso; Jessica C Piel; Meghan M Flaherty; Keith G Mansfield; Emily K Meseck; Tina Rubic-Schneider; Anne Serdakowski London; William R Tschantz; Markus Kurz; Duc Nguyen; Aaron Bourret; Matthew J Meyer; Jason E Faris; Mary J Janatpour; Vivien W Chan; Nicholas C Yoder; Kalli C Catcott; Molly A McShea; Xiuxia Sun; Hui Gao; Juliet Williams; Francesco Hofmann; Jeffrey A Engelman; Seth A Ettenberg; William R Sellers; Emma Lees. "Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers." Cancer discovery (2017).

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0109

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive
Quantitative measurement: 9.0

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4485000.0

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.04037

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.34

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.03564

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive
Quantitative measurement: 8.62

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1249000.0

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.01077

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive
Quantitative measurement: 7.73

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1410000.0

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive
Quantitative measurement: 8.81

Epitope: Epitope of LTV977 Fab on Cadherin-6
Chemical type: Discontinuous protein residues
Discontinuous residues: D503, G520, H521, Q522, F523, S524, F525, S526, L527, P529, A532, S533, G534, T538, I539, Q540, D541, N542, K543, L550, R552, V569, S571, D572, N573, D574, Y575, P576, V577
Source molecule (GenBank): P55285.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4048000.0