Reference: Sylvia Kamphuis; Kolbrún Hrafnkelsdóttir; Mark R Klein; Wilco de Jager; Margje H Haverkamp; Jolanda H M van Bilsen; Salvatore Albani; Wietse Kuis; Marca H M Wauben; Berent J Prakken. "Novel self-epitopes derived from aggrecan, fibrillin, and matrix metalloproteinase-3 drive distinct autoreactive T-cell responses in juvenile idiopathic arthritis and in health." Arthritis research & therapy (2006).

Epitope: aggrecan
Chemical type: Peptide from protein
Sequence: LSGLPSGGEVLEISV
Position: 1352-1366
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: aggrecan
Chemical type: Peptide from protein
Sequence: LSGLPSGGEVLEISV
Position: 1352-1366
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: aggrecan
Chemical type: Peptide from protein
Sequence: LSGLPSGGEVLEISV
Position: 1352-1366
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: aggrecan
Chemical type: Peptide from protein
Sequence: LSGLPSGGEVLEISV
Position: 1352-1366
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: aggrecan
Chemical type: Peptide from protein
Sequence: LSGLPSGGEVLEISV
Position: 1352-1366
Source molecule (GenBank): P16112.2
Assay category: TCell
Result: Positive-High
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: aggrecan3
Chemical type: Peptide from protein
Sequence: ISGLPSGGDDLETST
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: aggrecan3
Chemical type: Peptide from protein
Sequence: ISGLPSGGDDLETST
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: calpain
Chemical type: Peptide from protein
Sequence: HAYSVTGAEEVESNG
Position: 184-198
Source molecule (GenBank): NP_001139540.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: calpain
Chemical type: Peptide from protein
Sequence: HAYSVTGAEEVESNG
Position: 184-198
Source molecule (GenBank): NP_001139540.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: fibrillin
Chemical type: Peptide from protein
Sequence: CVDTRSGNCYLDIRP
Position: 1526-1540
Source molecule (GenBank): EAW77353.1
Assay category: TCell
Result: Positive-High
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: fibrillin
Chemical type: Peptide from protein
Sequence: CVDTRSGNCYLDIRP
Position: 1526-1540
Source molecule (GenBank): EAW77353.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: fibrillin
Chemical type: Peptide from protein
Sequence: CVDTRSGNCYLDIRP
Position: 1526-1540
Source molecule (GenBank): EAW77353.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: fibrillin
Chemical type: Peptide from protein
Sequence: CVDTRSGNCYLDIRP
Position: 1526-1540
Source molecule (GenBank): EAW77353.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: fibrillin
Chemical type: Peptide from protein
Sequence: CVDTRSGNCYLDIRP
Position: 1526-1540
Source molecule (GenBank): EAW77353.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MMP-1
Chemical type: Peptide from protein
Sequence: GVVSHSFPATLETQE
Position: 14-28
Source molecule (GenBank): AAV38949.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MMP-1
Chemical type: Peptide from protein
Sequence: GVVSHSFPATLETQE
Position: 14-28
Source molecule (GenBank): AAV38949.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MMP-3
Chemical type: Peptide from protein
Sequence: FFYFFTGSSQLEFDP
Position: 446-460
Source molecule (GenBank): AAA36321.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MMP-3
Chemical type: Peptide from protein
Sequence: FFYFFTGSSQLEFDP
Position: 446-460
Source molecule (GenBank): AAA36321.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MMP-3
Chemical type: Peptide from protein
Sequence: FFYFFTGSSQLEFDP
Position: 446-460
Source molecule (GenBank): AAA36321.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MMP-3
Chemical type: Peptide from protein
Sequence: FFYFFTGSSQLEFDP
Position: 446-460
Source molecule (GenBank): AAA36321.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MMP-3
Chemical type: Peptide from protein
Sequence: FFYFFTGSSQLEFDP
Position: 446-460
Source molecule (GenBank): AAA36321.1
Assay category: TCell
Result: Positive-High
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MMP-10
Chemical type: Peptide from protein
Sequence: SAFWPSLPSGLDAAY
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MMP-10
Chemical type: Peptide from protein
Sequence: SAFWPSLPSGLDAAY
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MMP-16
Chemical type: Peptide from protein
Sequence: VKEGHSPPDDVDIVI
Position: 539-553
Source molecule (GenBank): NP_005932.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MMP-16
Chemical type: Peptide from protein
Sequence: VKEGHSPPDDVDIVI
Position: 539-553
Source molecule (GenBank): NP_005932.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: tenascin
Chemical type: Peptide from protein
Sequence: EPVSGSFTTALDGPS
Position: 1789-1803
Source molecule (GenBank): P24821.2
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: tenascin
Chemical type: Peptide from protein
Sequence: EPVSGSFTTALDGPS
Position: 1789-1803
Source molecule (GenBank): P24821.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo