Reference: Obinna C Ubah; Eric W Lake; Gihan S Gunaratne; Joseph P Gallant; Marie Fernie; Austin J Robertson; Jonathan S Marchant; Tyler D Bold; Ryan A Langlois; William E Matchett; Joshua M Thiede; Ke Shi; Lulu Yin; Nicholas H Moeller; Surajit Banerjee; Laura Ferguson; Marina Kovaleva; Andrew J Porter; Hideki Aihara; Aaron M LeBeau; Caroline J Barelle. "Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography." Nature communications (2021).

Epitope: Epitope of VNAR 3B4 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, A372, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, P412, G413, D427, V503
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VNAR 3B4 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, A372, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, P412, G413, D427, V503
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VNAR 3B4 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, A372, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, P412, G413, D427, V503
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 17.2

Epitope: Epitope of VNAR 3B4 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, A372, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, P412, G413, D427, V503
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VNAR 3B4 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, A372, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, P412, G413, D427, V503
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VNAR 3B4 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, A372, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, P412, G413, D427, V503
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of VNAR 3B4 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, A372, F374, S375, T376, F377, K378, C379, Y380, G381, V382, S383, P384, T385, K386, P412, G413, D427, V503
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.92

Epitope: Epitope of VNAR 2C02 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, F347, S349, Y351, A352, N354, R355, G446, Y449, N450, L452, I468, T470, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 63.0

Epitope: Epitope of VNAR 2C02 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, F347, S349, Y351, A352, N354, R355, G446, Y449, N450, L452, I468, T470, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VNAR 2C02 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, F347, S349, Y351, A352, N354, R355, G446, Y449, N450, L452, I468, T470, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.96

Epitope: Epitope of VNAR 2C02 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, F347, S349, Y351, A352, N354, R355, G446, Y449, N450, L452, I468, T470, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VNAR 2C02 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, F347, S349, Y351, A352, N354, R355, G446, Y449, N450, L452, I468, T470, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VNAR 2C02 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, F347, S349, Y351, A352, N354, R355, G446, Y449, N450, L452, I468, T470, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VNAR 2C02 on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, F347, S349, Y351, A352, N354, R355, G446, Y449, N450, L452, I468, T470, V483, E484, F490, L492
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low