Reference: Taiki Aoshi; Toshi Nagata; Mina Suzuki; Masato Uchijima; Dai Hashimoto; Alireza Rafiei; Takafumi Suda; Kingo Chida; Yukio Koide. "Identification of an HLA-A*0201-restricted T-cell epitope on the MPT51 protein, a major secreted protein derived from Mycobacterium tuberculosis, by MPT51 overlapping peptide screening." Infection and immunity (2008).

Epitope: p001
Chemical type: Peptide from protein
Sequence: APYENIMVPSPSMGRDIPVA
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p011
Chemical type: Peptide from protein
Sequence: PSMGRDIPVAFLAGGPMAVY
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p031
Chemical type: Peptide from protein
Sequence: LLDAFNAGPDVSNWVTAGNA
Position: 64-83
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p041
Chemical type: Peptide from protein
Sequence: VSNWVTAGNAMNTLAGKGIS
Position: 74-93
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MPT51 p53-62
Chemical type: Peptide from protein
Sequence: TLAGKGISVV
Position: 86-95
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MPT51 p53-62
Chemical type: Peptide from protein
Sequence: TLAGKGISVV
Position: 86-95
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Positive
Host: F 2-3 months
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: MPT51 p53-62
Chemical type: Peptide from protein
Sequence: TLAGKGISVV
Position: 86-95
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MPT51 p53-62
Chemical type: Peptide from protein
Sequence: TLAGKGISVV
Position: 86-95
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Positive
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MPT51 p53-62
Chemical type: Peptide from protein
Sequence: TLAGKGISVV
Position: 86-95
Source molecule (GenBank): P0A4V6.1
Assay category: MhcBinding
Result: Positive-High

Epitope: p061
Chemical type: Peptide from protein
Sequence: VVAPAGGAYSMYTNWEQDGS
Position: 94-113
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p071
Chemical type: Peptide from protein
Sequence: MYTNWEQDGSKQWDTFLSAE
Position: 104-123
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p081
Chemical type: Peptide from protein
Sequence: KQWDTFLSAELPDWLAANRG
Position: 114-133
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p091
Chemical type: Peptide from protein
Sequence: LPDWLAANRGLAPGGHAAVG
Position: 124-143
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p101
Chemical type: Peptide from protein
Sequence: KQWDTFLSAELPDWLAANRG
Position: 114-133
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p111
Chemical type: Peptide from protein
Sequence: AAQGGYGAMALAAFHPDRFG
Position: 144-163
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p121
Chemical type: Peptide from protein
Sequence: LAAFHPDRFGFAGSMSGFLY
Position: 154-173
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p141
Chemical type: Peptide from protein
Sequence: PSNTTTNGAIAAGMQQFGGV
Position: 174-193
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p151
Chemical type: Peptide from protein
Sequence: AAGMQQFGGVDTNGMWGAPQ
Position: 184-203
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p161
Chemical type: Peptide from protein
Sequence: DTNGMWGAPQLGRWKWHDPW
Position: 194-213
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p171
Chemical type: Peptide from protein
Sequence: LGRWKWHDPWVHASLLAQNN
Position: 204-223
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Positive
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p181
Chemical type: Peptide from protein
Sequence: VHASLLAQNNTRVWVWSPTN
Position: 214-233
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p191
Chemical type: Peptide from protein
Sequence: TRVWVWSPTNPGASDPAAMI
Position: 224-243
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Positive-Low
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p211
Chemical type: Peptide from protein
Sequence: GQAAEAMGNSRMFYNQYRSV
Position: 244-263
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p221
Chemical type: Peptide from protein
Sequence: RMFYNQYRSVGGHNGHFDFP
Position: 254-273
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p231
Chemical type: Peptide from protein
Sequence: GGHNGHFDFPASGDNGWGSW
Position: 264-283
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: p241
Chemical type: Peptide from protein
Sequence: ASGDNGWGSWAPQLGAMSGD
Position: 274-293
Source molecule (GenBank): P0A4V6.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MPT51 p21-29
Chemical type: Peptide from protein
Sequence: FLAGGPHAV
Position: 54-62
Source molecule (GenBank): P0A4V6.1
Assay category: MhcBinding
Result: Positive-High

Epitope: MPT51 p53-61
Chemical type: Peptide from protein
Sequence: TLAGKGISV
Position: 86-94
Source molecule (GenBank): P0A4V6.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: Ag85A
Chemical type: Peptide from protein
Sequence: KLIANNTRV
Position: 242-250
Source molecule (GenBank): Q847N5.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: ESAT6
Chemical type: Peptide from protein
Sequence: LLDEGKQSL
Position: 28-36
Source molecule (GenBank): P0A564.2
Assay category: MhcBinding
Result: Positive-Low

Epitope: LLO
Chemical type: Peptide from protein
Sequence: GYKDGNEYI
Position: 91-99
Source molecule (GenBank): P13128.1
Assay category: MhcBinding
Result: Negative