LiteFold/IEDB huggingface dataset:
Reference: Weiwen Zhang; Fernanda M Roversi; Anna B Morris; Kristina Ortiz; Grace Zhou; Annette Hadley; Xueqiong Zhang; Juliete A F Silva; Cynthia P Breeden; Zhuldyz Zhanzak; Haydn T Kissick; Christian P Larsen. "Major histocompatibility complex and peptide specificity underpin CD8<sup>+</sup> T cell direct alloresponse." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons (2025).

Epitope: NLV
Chemical type: Peptide from protein
Sequence: NLVPMVATV
Position: 485-493
Source molecule (GenBank): AAA45994.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NLV
Chemical type: Peptide from protein
Sequence: NLVPMVATV
Position: 485-493
Source molecule (GenBank): AAA45994.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NLV
Chemical type: Peptide from protein
Sequence: NLVPMVATV
Position: 485-493
Source molecule (GenBank): AAA45994.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NDUFA1.16
Chemical type: Peptide from protein
Sequence: LLIPGLATAY
Position: 16-25
Source molecule (GenBank): Q6IBB5.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NDUFA1.16
Chemical type: Peptide from protein
Sequence: LLIPGLATAY
Position: 16-25
Source molecule (GenBank): Q6IBB5.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NDUFA1.16
Chemical type: Peptide from protein
Sequence: LLIPGLATAY
Position: 16-25
Source molecule (GenBank): Q6IBB5.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: ATP5F1A.449
Chemical type: Peptide from protein
Sequence: FGSDLDAATQQL
Position: 264-275
Source molecule (GenBank): AAH03119.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: ATP5F1A.449
Chemical type: Peptide from protein
Sequence: FGSDLDAATQQL
Position: 264-275
Source molecule (GenBank): AAH03119.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: ATP5F1A.449
Chemical type: Peptide from protein
Sequence: FGSDLDAATQQL
Position: 264-275
Source molecule (GenBank): AAH03119.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: Liyen Loh; Philippa M Saunders; Camilla Faoro; Neus Font-Porterias; Neda Nemat-Gorgani; Genelle F Harrison; Suraju Sadeeq; Luca Hensen; Shu Cheng Wong; Jacqueline Widjaja; E Bridie Clemens; Shiying Zhu; Katherine M Kichula; Sudan Tao; Faming Zhu; Gonzalo Montero-Martin; Marcelo Fernandez-Vina; Lisbeth A Guethlein; Julian P Vivian; Jane Davies; Alexander J Mentzer; Stephen J Oppenheimer; William Pomat; Alexander G Ioannidis; Carmina Barberena-Jonas; Andrés Moreno-Estrada; Adrian Miller; Peter Parham; Jamie Rossjohn; Steven Y C Tong; Katherine Kedzierska; Andrew G Brooks; Paul J Norman. "An archaic HLA class I receptor allele diversifies natural killer cell-driven immunity in First Nations peoples of Oceania." Cell (2024).

Epitope: TW9 (549-557)
Chemical type: Peptide from protein
Sequence: TYQWIIRNW
Position: 549-557
Source molecule (GenBank): P03428.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.0

Epitope: TW9 (549-557)
Chemical type: Peptide from protein
Sequence: TYQWIIRNW
Position: 549-557
Source molecule (GenBank): P03428.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.4

Epitope: NEF (134-141)
Chemical type: Peptide from protein
Sequence: RYPLTFGW
Position: 134-141
Source molecule (GenBank): Q9YYU8.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 3.0

Epitope: NEF (134-141)
Chemical type: Peptide from protein
Sequence: RYPLTFGW
Position: 134-141
Source molecule (GenBank): Q9YYU8.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.6

Epitope: AW10 (850-859)
Chemical type: Peptide from protein
Sequence: ASLNLPAVSW
Position: 850-859
Source molecule (GenBank): P35221.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.1

Epitope: AW10 (850-859)
Chemical type: Peptide from protein
Sequence: ASLNLPAVSW
Position: 850-859
Source molecule (GenBank): P35221.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.0

Epitope: AW10 (850-859)
Chemical type: Peptide from protein
Sequence: ASLNLPAVSW
Position: 850-859
Source molecule (GenBank): P35221.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.75
Reference: Brayden D Whitlock; Yingze Ma; Gwenaëlle Conseil; Alicia R O'Brien; Mayukh Banerjee; Diane P Swanlund; Z Ping Lin; Yao Wang; X Chris Le; John D Schuetz; Susan P C Cole; Elaine M Leslie. "Differential Selectivity of Human and Mouse ABCC4/Abcc4 for Arsenic Metabolites." Drug metabolism and disposition: the biological fate of chemicals (2024).

Epitope: M4I-10
Chemical type: Peptide from protein
Sequence: HVQDFTAF
Position: 411-418
Source molecule (GenBank): A0A2R8Y6V8.1
Assay category: BCell
Result: Positive

Epitope: M4I-10
Chemical type: Peptide from protein
Sequence: HVQDFTAF
Position: 411-418
Source molecule (GenBank): A0A2R8Y6V8.1
Assay category: BCell
Result: Positive

Epitope: M4I-10
Chemical type: Peptide from protein
Sequence: HVQDFTAF
Position: 411-418
Source molecule (GenBank): A0A2R8Y6V8.1
Assay category: BCell
Result: Positive
Reference: Junjuan Wang; Mengzhen Hao; QianWei Wang; Manman Liu; Guirong Liu; Shiwen Han; Xiaoyan Zhao; Huilian Che. "The conformational epitope of Ara h 5 was crucial to the severe reactivity of peanut allergy." Molecular immunology (2024).

Epitope: WETIYSR
Chemical type: Peptide, no natural source
Sequence: WETIYSR
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: WETIYSR
Chemical type: Peptide, no natural source
Sequence: WETIYSR
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: FHWWYLK
Chemical type: Peptide, no natural source
Sequence: FHWWYLK
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: FHWWYLK
Chemical type: Peptide, no natural source
Sequence: FHWWYLK
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: GPLWNVN
Chemical type: Peptide, no natural source
Sequence: GPLWNVN
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: FMHREPD
Chemical type: Peptide, no natural source
Sequence: FMHREPD
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: FLHRDND
Chemical type: Peptide, no natural source
Sequence: FLHRDND
Assay category: BCell
Result: Positive
Host:  6-8 weeks
Reference: Yurong Duan; Xiaowen Tang; Sha Liu; Weiwei Cui; Mengge Li; Shiyu Tang; Wenrong Yao; Wenjie Li; Jiachen Weng; Junjie Zhao; Zhun Wei. "Structure-guided design and evaluation of CRM197-scaffolded vaccine targeting GnRH for animal immunocastration." Applied microbiology and biotechnology (2024).

Epitope: GnRH peptide
Chemical type: Peptide from protein
Sequence: HWSYGLRPG
Position: 29-37
Source molecule (GenBank): Q14AC4.1
Assay category: BCell
Result: Positive
Host:  8 weeks

Epitope: GnRH peptide
Chemical type: Peptide from protein
Sequence: HWSYGLRPG
Position: 29-37
Source molecule (GenBank): Q14AC4.1
Assay category: BCell
Result: Positive
Host: M 8 weeks
Reference: Shan Wang; Shasha Jiang; Xu Li; Huan Huang; Xu Qiu; Meng Yu; Xiaoli Yang; Fengjun Liu; Chen Wang; Wen Shen; Yunyang Wang; Bin Wang. "FGL2<sub>172-220</sub> peptides improve the antitumor effect of HCMV-IE1mut vaccine against glioblastoma by modulating immunosuppressive cells in the tumor microenvironment." Oncoimmunology (2024).

Epitope: FGL2<sub>172-220<sub>
Chemical type: Peptide from protein
Sequence: NLTVVVNSLDGKCSKCPSQEHMQSQPVQHLIYKDCSDHYVLGRRSSGAY
Position: 172-220
Source molecule (GenBank): NP_032039.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks

Epitope: FGL2<sub>172-220<sub>
Chemical type: Peptide from protein
Sequence: NLTVVVNSLDGKCSKCPSQEHMQSQPVQHLIYKDCSDHYVLGRRSSGAY
Position: 172-220
Source molecule (GenBank): NP_032039.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FGL2<sub>172-220<sub>
Chemical type: Peptide from protein
Sequence: NLTVVVNSLDGKCSKCPSQEHMQSQPVQHLIYKDCSDHYVLGRRSSGAY
Position: 172-220
Source molecule (GenBank): NP_032039.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FGL2<sub>172-220<sub>
Chemical type: Peptide from protein
Sequence: NLTVVVNSLDGKCSKCPSQEHMQSQPVQHLIYKDCSDHYVLGRRSSGAY
Position: 172-220
Source molecule (GenBank): NP_032039.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FGL2<sub>172-220<sub>
Chemical type: Peptide from protein
Sequence: NLTVVVNSLDGKCSKCPSQEHMQSQPVQHLIYKDCSDHYVLGRRSSGAY
Position: 172-220
Source molecule (GenBank): NP_032039.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FGL2<sub>172-220<sub>
Chemical type: Peptide from protein
Sequence: NLTVVVNSLDGKCSKCPSQEHMQSQPVQHLIYKDCSDHYVLGRRSSGAY
Position: 172-220
Source molecule (GenBank): NP_032039.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Reference: Shu-Jian Zhang; Bei Niu; Shi-Meng Liu; Zhi-Gao Bu; Rong-Hong Hua. "Identification of linear B cell epitopes on the E146L protein of African swine fever virus with monoclonal antibodies." Virology journal (2024).

Epitope: EP1
Chemical type: Peptide from protein
Sequence: GWSPFKYSKGNT
Position: 30-41
Source molecule (GenBank): QBH90616.1
Assay category: BCell
Result: Positive
Host: F

Epitope: EP1
Chemical type: Peptide from protein
Sequence: GWSPFKYSKGNT
Position: 30-41
Source molecule (GenBank): QBH90616.1
Assay category: BCell
Result: Positive
Host: F

Epitope: EP1
Chemical type: Peptide from protein
Sequence: GWSPFKYSKGNT
Position: 30-41
Source molecule (GenBank): QBH90616.1
Assay category: BCell
Result: Positive
Host: F

Epitope: EP1
Chemical type: Peptide from protein
Sequence: GWSPFKYSKGNT
Position: 30-41
Source molecule (GenBank): QBH90616.1
Assay category: BCell
Result: Positive
Host: F

Epitope: EP1
Chemical type: Peptide from protein
Sequence: GWSPFKYSKGNT
Position: 30-41
Source molecule (GenBank): QBH90616.1
Assay category: BCell
Result: Positive

Epitope: EP1
Chemical type: Peptide from protein
Sequence: GWSPFKYSKGNT
Position: 30-41
Source molecule (GenBank): QBH90616.1
Assay category: BCell
Result: Positive

Epitope: EP2
Chemical type: Peptide from protein
Sequence: PDESSIAYMRFRN
Position: 47-59
Source molecule (GenBank): QBH90616.1
Assay category: BCell
Result: Positive
Host: F

Epitope: EP2
Chemical type: Peptide from protein
Sequence: PDESSIAYMRFRN
Position: 47-59
Source molecule (GenBank): QBH90616.1
Assay category: BCell
Result: Positive
Host: F

Epitope: EP2
Chemical type: Peptide from protein
Sequence: PDESSIAYMRFRN
Position: 47-59
Source molecule (GenBank): QBH90616.1
Assay category: BCell
Result: Positive
Host: F

Epitope: EP2
Chemical type: Peptide from protein
Sequence: PDESSIAYMRFRN
Position: 47-59
Source molecule (GenBank): QBH90616.1
Assay category: BCell
Result: Positive-Low

Epitope: EP7
Chemical type: Peptide from protein
Sequence: TLTGLQRII
Position: 138-146
Source molecule (GenBank): QBH90616.1
Assay category: BCell
Result: Positive
Host: F

Epitope: EP7
Chemical type: Peptide from protein
Sequence: TLTGLQRII
Position: 138-146
Source molecule (GenBank): QBH90616.1
Assay category: BCell
Result: Positive
Host: F

Epitope: EP7
Chemical type: Peptide from protein
Sequence: TLTGLQRII
Position: 138-146
Source molecule (GenBank): QBH90616.1
Assay category: BCell
Result: Positive
Host: F

Epitope: EP7
Chemical type: Peptide from protein
Sequence: TLTGLQRII
Position: 138-146
Source molecule (GenBank): QBH90616.1
Assay category: BCell
Result: Positive
Host: F

Epitope: EP7
Chemical type: Peptide from protein
Sequence: TLTGLQRII
Position: 138-146
Source molecule (GenBank): QBH90616.1
Assay category: BCell
Result: Positive-Low
Reference: Isabela Ferreira Soares; Barbara de Oliveira Baptista; Ada da Silva Matos; Rodrigo Nunes Rodrigues-da-Silva; Mario Antonio Kujbida Junior; Letusa Albrecht; Cinthia Magalhães Rodolphi; Kézia Katiani Gorza Scopel; Ana Luiza Carneiro Alencar; Rodrigo Medeiros de Souza; Hugo Amorim Dos Santos de Souza; Evelyn Kety Pratt Riccio; Jenifer Peixoto de Barros; Paulo Renato Rivas Totino; Cláudio Tadeu Daniel-Ribeiro; Lilian Rose Pratt-Riccio; Josué da Costa Lima-Junior. "Characterization of T and B cell epitopes in PvCyRPA by studying the naturally acquired immune response in Brazilian Amazon communities." Scientific reports (2024).

Epitope: B1-PvCyRPA(81−91)
Chemical type: Peptide from protein
Sequence: INSTWETQTTL
Position: 81-91
Source molecule (GenBank): A5K678
Assay category: BCell
Result: Positive

Epitope: B1-PvCyRPA(81−91)
Chemical type: Peptide from protein
Sequence: INSTWETQTTL
Position: 81-91
Source molecule (GenBank): A5K678
Assay category: BCell
Result: Positive

Epitope: B2-PvCyRPA(119−129)
Chemical type: Peptide from protein
Sequence: YKQRSKREGTI
Position: 119-129
Source molecule (GenBank): A5K678
Assay category: BCell
Result: Positive

Epitope: B2-PvCyRPA(119−129)
Chemical type: Peptide from protein
Sequence: YKQRSKREGTI
Position: 119-129
Source molecule (GenBank): A5K678
Assay category: BCell
Result: Negative

Epitope: B3-PvCyRPA(134−151)
Chemical type: Peptide from protein
Sequence: NSVTGTIYQKEDVQIDKE
Position: 134-151
Source molecule (GenBank): A5K678
Assay category: BCell
Result: Positive

Epitope: B3-PvCyRPA(134−151)
Chemical type: Peptide from protein
Sequence: NSVTGTIYQKEDVQIDKE
Position: 134-151
Source molecule (GenBank): A5K678
Assay category: BCell
Result: Negative

Epitope: B4-PvCyRPA(181−192)
Chemical type: Peptide from protein
Sequence: SYEYKTANKDNF
Position: 181-192
Source molecule (GenBank): A5K678
Assay category: BCell
Result: Positive

Epitope: B4-PvCyRPA(181−192)
Chemical type: Peptide from protein
Sequence: SYEYKTANKDNF
Position: 181-192
Source molecule (GenBank): A5K678
Assay category: BCell
Result: Positive

Epitope: B5-PvCyRPA(241−249)
Chemical type: Peptide from protein
Sequence: RISTNNTAR
Position: 241-249
Source molecule (GenBank): A5K678
Assay category: BCell
Result: Positive

Epitope: B5-PvCyRPA(241−249)
Chemical type: Peptide from protein
Sequence: RISTNNTAR
Position: 241-249
Source molecule (GenBank): A5K678
Assay category: BCell
Result: Positive

Epitope: B7-PvCyRPA(312−330)
Chemical type: Peptide from protein
Sequence: TEQNAIVVKPKVQNDDLNG
Position: 312-330
Source molecule (GenBank): A5K678
Assay category: BCell
Result: Positive

Epitope: B7-PvCyRPA(312−330)
Chemical type: Peptide from protein
Sequence: TEQNAIVVKPKVQNDDLNG
Position: 312-330
Source molecule (GenBank): A5K678
Assay category: BCell
Result: Positive
Reference: Qinggang Xie; Yuhao Huang; Xianli Zhang; Xiaoxi Xu; Zhenxing Li. "Development of an Indirect Competitive ELISA Based on a Stable Epitope of β-Lactoglobulin for Its Detection in Hydrolyzed Formula Milk Powder." Foods (Basel, Switzerland) (2024).

Epitope: BLG-1
Chemical type: Peptide from protein
Sequence: KPTPEGDLEILLQK
Position: 63-76
Source molecule (GenBank): P02754.3
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: BLG-2
Chemical type: Peptide from protein
Sequence: CAQKKIIAEKTKIPAVFKIDA
Position: 82-102
Source molecule (GenBank): P02754.3
Assay category: BCell
Result: Positive-High
Host: F 6-8 weeks

Epitope: BLG-2
Chemical type: Peptide from protein
Sequence: CAQKKIIAEKTKIPAVFKIDA
Position: 82-102
Source molecule (GenBank): P02754.3
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: BLG-3
Chemical type: Peptide from protein
Sequence: KALKALPMHIRLSFN
Position: 154-168
Source molecule (GenBank): P02754.3
Assay category: BCell
Result: Positive
Host: F 6-8 weeks
Reference: Pushpak Bhattacharjee; Miha Pakusch; Matthew Lacorcia; Chris Y Chiu; Xin Liu; Eleonora Tresoldi; Abby Foster; Laura King; Fergus J Cameron; Stuart I Mannering. "A minority of proliferating human CD4<sup>+</sup> T cells in antigen-driven proliferation assays are antigen specific." Frontiers in immunology (2024).

Epitope: C-peptide 33-63
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ
Position: 57-87
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: Jurkat cell (T cell)
Tissue: blood
Culture conditions: Engineered

Epitope: C-peptide 33-63
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ
Position: 57-87
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: Peng Liu; Mei-Ling Huang; Hua Guo; Matthew McCallum; Jun-Yu Si; Yuan-Mei Chen; Chun-Li Wang; Xiao Yu; Lu-Lu Shi; Qing Xiong; Cheng-Bao Ma; John E Bowen; Fei Tong; Chen Liu; Ye-Hui Sun; Xiao Yang; Jing Chen; Ming Guo; Jing Li; Davide Corti; David Veesler; Zheng-Li Shi; Huan Yan. "Design of customized coronavirus receptors." Nature (2024).

Epitope: Epitope of Fab S2L20 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: P26, Y28, T63, P82, V83, P85, N87, D88, T108, T109, D111, K113, T114, T236, R237, Y269, L270
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of Fab S2L20 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: P26, Y28, T63, P82, V83, P85, N87, D88, T108, T109, D111, K113, T114, T236, R237, Y269, L270
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab S2L20 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: P26, Y28, T63, P82, V83, P85, N87, D88, T108, T109, D111, K113, T114, T236, R237, Y269, L270
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab S2L20 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: P26, Y28, T63, P82, V83, P85, N87, D88, T108, T109, D111, K113, T114, T236, R237, Y269, L270
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab S2L20 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: P26, Y28, T63, P82, V83, P85, N87, D88, T108, T109, D111, K113, T114, T236, R237, Y269, L270
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab S2L20 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: P26, Y28, T63, P82, V83, P85, N87, D88, T108, T109, D111, K113, T114, T236, R237, Y269, L270
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab S2L20 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: P26, Y28, T63, P82, V83, P85, N87, D88, T108, T109, D111, K113, T114, T236, R237, Y269, L270
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab S2L20 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: P26, Y28, T63, P82, V83, P85, N87, D88, T108, T109, D111, K113, T114, T236, R237, Y269, L270
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Reference: Lu Wang; Jialing Wang; Jihong Li; Thomas Walz; Barry S Coller. "An αIIbβ3 monoclonal antibody traps a semiextended conformation and allosterically inhibits large ligand binding." Blood advances (2024).

Epitope: Epitope of Fab R21D10 on integrin beta-3
Chemical type: Discontinuous protein residues
Discontinuous residues: D54, E55, A56, L57, P58, L59, N74, Q466, E468, N470, S471, H472, R473, F481, Q496, K545, C549
Source molecule (GenBank): P05106.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab R21D10 on integrin beta-3
Chemical type: Discontinuous protein residues
Discontinuous residues: D54, E55, A56, L57, P58, L59, N74, Q466, E468, N470, S471, H472, R473, F481, Q496, K545, C549
Source molecule (GenBank): P05106.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab R21D10 on integrin beta-3
Chemical type: Discontinuous protein residues
Discontinuous residues: D54, E55, A56, L57, P58, L59, N74, Q466, E468, N470, S471, H472, R473, F481, Q496, K545, C549
Source molecule (GenBank): P05106.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab R21D10 on integrin beta-3
Chemical type: Discontinuous protein residues
Discontinuous residues: D54, E55, A56, L57, P58, L59, N74, Q466, E468, N470, S471, H472, R473, F481, Q496, K545, C549
Source molecule (GenBank): P05106.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab R21D10 on integrin beta-3
Chemical type: Discontinuous protein residues
Discontinuous residues: D54, E55, A56, L57, P58, L59, N74, Q466, E468, N470, S471, H472, R473, F481, Q496, K545, C549
Source molecule (GenBank): P05106.2
Assay category: BCell
Result: Positive
Reference: Bryce A Harrison; James E Dowling; Matthew G Bursavich; Dawn M Troast; Katherine M Chong; Kristopher N Hahn; Cheng Zhong; Kristen M Mulvihill; Hanh Nguyen; Meghan F Monroy; Qi Qiao; Brian Sosa; Siavash Mostafavi; Inese Smukste; Dooyoung Lee; Laura Cappellucci; Elizabeth H Konopka; Patrycja Nowakowski; Lukasz Stawski; Mayra Senices; Minh Hai Nguyen; Parmita S Kapoor; Lia Luus; Andrew Sullivan; Andrea Bortolato; Mats Svensson; Eugene R Hickey; Kyle D Konze; Tyler Day; Byungchan Kim; Ana Negri; Aleksey I Gerasyuto; Terence I Moy; Min Lu; Adrian S Ray; Liangsu Wang; Dan Cui; Fu-Yang Lin; Blaise Lippa; Bruce N Rogers. "The Discovery of MORF-627, a Highly Selective Conformationally-Biased Zwitterionic Integrin αvβ6 Inhibitor for Fibrosis." Journal of medicinal chemistry (2024).

Epitope: Epitope of Fab 17E6 R54N on integrin alpha-V
Chemical type: Discontinuous protein residues
Discontinuous residues: Y110, E147, M148, S174, Q175, D176, I177, Q182, F207, N228, V229, Y230, S231, I232, K233, N235, Q237, R241, T242
Source molecule (GenBank): P06756.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2.23
Host: F 8 weeks

Epitope: Epitope of Fab 17E6 R54N on integrin alpha-V
Chemical type: Discontinuous protein residues
Discontinuous residues: Y110, E147, M148, S174, Q175, D176, I177, Q182, F207, N228, V229, Y230, S231, I232, K233, N235, Q237, R241, T242
Source molecule (GenBank): P06756.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2.57
Host: F 8 weeks

Epitope: Epitope of Fab 17E6 R54N on integrin alpha-V
Chemical type: Discontinuous protein residues
Discontinuous residues: Y110, E147, M148, S174, Q175, D176, I177, Q182, F207, N228, V229, Y230, S231, I232, K233, N235, Q237, R241, T242
Source molecule (GenBank): P06756.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2.53
Host: F 8 weeks

Epitope: Epitope of Fab 17E6 R54N on integrin alpha-V
Chemical type: Discontinuous protein residues
Discontinuous residues: Y110, E147, M148, S174, Q175, D176, I177, Q182, F207, N228, V229, Y230, S231, I232, K233, N235, Q237, R241, T242
Source molecule (GenBank): P06756.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2.49
Host: F 8 weeks
Reference: Kaho Shionoya; Jae-Hyun Park; Toru Ekimoto; Junko S Takeuchi; Junki Mifune; Takeshi Morita; Naito Ishimoto; Haruka Umezawa; Kenichiro Yamamoto; Chisa Kobayashi; Atsuto Kusunoki; Norimichi Nomura; So Iwata; Masamichi Muramatsu; Jeremy R H Tame; Mitsunori Ikeguchi; Sam-Yong Park; Koichi Watashi. "Structural basis for hepatitis B virus restriction by a viral receptor homologue." Nature communications (2024).

Epitope: Epitope of YN69083 Fab on mNTCP
Chemical type: Discontinuous protein residues
Discontinuous residues: R21, D24, N86, I88, Y146, K212, F216, A217, V272, A273, F274, P275, P276, E277, V278, P281, F283, F284
Source molecule (GenBank): ALX38777.1
Assay category: BCell
Result: Positive
Host: F 6 weeks