Reference: Azad Mamedov; Nadezhda Vorobyeva; Ioanna Filimonova; Maria Zakharova; Ivan Kiselev; Vitalina Bashinskaya; Natalia Baulina; Alexey Boyko; Alexander Favorov; Olga Kulakova; Rustam Ziganshin; Ivan Smirnov; Alina Poroshina; Igor Shilovskiy; Musa Khaitov; Yuri Sykulev; Olga Favorova; Valentin Vlassov; Alexander Gabibov; Alexey Belogurov. "Protective Allele for Multiple Sclerosis HLA-DRB1*01:01 Provides Kinetic Discrimination of Myelin and Exogenous Antigenic Peptides." Frontiers in immunology (2019).

Epitope: MBP 1-27
Chemical type: Peptide from protein
Sequence: MASQKRPSQRHGSKYLATASTMDHARHG
Position: 1-28
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Negative

Epitope: MBP 1-27
Chemical type: Peptide from protein
Sequence: MASQKRPSQRHGSKYLATASTMDHARHG
Position: 1-28
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Negative

Epitope: MBP 17-41
Chemical type: Peptide from protein
Sequence: TASTMDHARHGFLPRHRDTGILDSI
Position: 18-42
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Negative

Epitope: MBP 17-41
Chemical type: Peptide from protein
Sequence: TASTMDHARHGFLPRHRDTGILDSI
Position: 18-42
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Negative

Epitope: MBP 25-54
Chemical type: Peptide from protein
Sequence: RHGFLPRHRDTGILDSIGRFFGGDRGAPKR
Position: 26-55
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Positive-Low

Epitope: MBP 25-54
Chemical type: Peptide from protein
Sequence: RHGFLPRHRDTGILDSIGRFFGGDRGAPKR
Position: 26-55
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Negative

Epitope: MBP 43-68
Chemical type: Peptide from protein
Sequence: RFFGGDRGAPKRGSGKDSHHPARTAH
Position: 44-69
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Negative

Epitope: MBP 43-68
Chemical type: Peptide from protein
Sequence: RFFGGDRGAPKRGSGKDSHHPARTAH
Position: 44-69
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Negative

Epitope: MBP 81-104
Chemical type: Peptide from protein
Sequence: QDENPVVHFFKNIVTPRTPPPSQG
Position: 82-105
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Positive-High

Epitope: MBP 81-104
Chemical type: Peptide from protein
Sequence: QDENPVVHFFKNIVTPRTPPPSQG
Position: 82-105
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 22.0

Epitope: MBP 107-132
Chemical type: Peptide from protein
Sequence: RGLSLSRFSWGAEGQRPGFGYGGRAS
Position: 108-133
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Negative

Epitope: MBP 107-132
Chemical type: Peptide from protein
Sequence: RGLSLSRFSWGAEGQRPGFGYGGRAS
Position: 108-133
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Negative

Epitope: MBP 123-140
Chemical type: Peptide from protein
Sequence: PGFGYGGRASDYKSAHKGF
Position: 124-142
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Negative

Epitope: MBP 123-140
Chemical type: Peptide from protein
Sequence: PGFGYGGRASDYKSAHKGF
Position: 124-142
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Negative

Epitope: MBP 146-170
Chemical type: Peptide from protein
Sequence: AQGTLSKIFKLGGRDSRSGSPMARR
Position: 147-171
Source molecule (GenBank): AAH08749.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MBP 146-170
Chemical type: Peptide from protein
Sequence: AQGTLSKIFKLGGRDSRSGSPMARR
Position: 147-171
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Negative

Epitope: MBP 146-170
Chemical type: Peptide from protein
Sequence: AQGTLSKIFKLGGRDSRSGSPMARR
Position: 147-171
Source molecule (GenBank): AAH08749.3
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 52.0

Epitope: HA 306-318
Chemical type: Peptide from protein
Sequence: PKYVKQNTLKLAT
Position: 306-318
Source molecule (GenBank): AAA43143.1
Assay category: MhcBinding
Result: Negative

Epitope: HA 306-318
Chemical type: Peptide from protein
Sequence: PKYVKQNTLKLAT
Position: 306-318
Source molecule (GenBank): AAA43143.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 52.0