Reference: Jolene Su Yi Tan; Bernett Lee; Jackwee Lim; Dong Rui Ma; Jia Xin Goh; Suh Yee Goh; Muhammad Yaaseen Gulam; Ser Mei Koh; Weiling Wendy Lee; Lei Feng; Qing Wang; Yinxia Chao; Olaf Rötzschke; Eng King Tan. "Parkinson's Disease-Specific Autoantibodies against the Neuroprotective Co-Chaperone STIP1." Cells (2022).

Epitope: STIP1 peptide 1
Chemical type: Peptide from protein
Sequence: MEQVNELKEKGNKALSVG
Position: 1-18
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 1
Chemical type: Peptide from protein
Sequence: MEQVNELKEKGNKALSVG
Position: 1-18
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 2
Chemical type: Peptide from protein
Sequence: ELKEKGNKALSVGNIDDA
Position: 6-23
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 2
Chemical type: Peptide from protein
Sequence: ELKEKGNKALSVGNIDDA
Position: 6-23
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 3
Chemical type: Peptide from protein
Sequence: GNKALSVGNIDDALQCYS
Position: 11-28
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 3
Chemical type: Peptide from protein
Sequence: GNKALSVGNIDDALQCYS
Position: 11-28
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 4
Chemical type: Peptide from protein
Sequence: SVGNIDDALQCYSEAIKL
Position: 16-33
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 4
Chemical type: Peptide from protein
Sequence: SVGNIDDALQCYSEAIKL
Position: 16-33
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 5
Chemical type: Peptide from protein
Sequence: DDALQCYSEAIKLDPHNH
Position: 21-38
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 5
Chemical type: Peptide from protein
Sequence: DDALQCYSEAIKLDPHNH
Position: 21-38
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 36
Chemical type: Peptide from protein
Sequence: MTTLSVLLGVDLGSMDEE
Position: 176-193
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 36
Chemical type: Peptide from protein
Sequence: MTTLSVLLGVDLGSMDEE
Position: 176-193
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 37
Chemical type: Peptide from protein
Sequence: VLLGVDLGSMDEEEEIAT
Position: 181-198
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 37
Chemical type: Peptide from protein
Sequence: VLLGVDLGSMDEEEEIAT
Position: 181-198
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 38
Chemical type: Peptide from protein
Sequence: DLGSMDEEEEIATPPPPP
Position: 186-203
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 38
Chemical type: Peptide from protein
Sequence: DLGSMDEEEEIATPPPPP
Position: 186-203
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 39
Chemical type: Peptide from protein
Sequence: DEEEEIATPPPPPPPKKE
Position: 191-208
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 39
Chemical type: Peptide from protein
Sequence: DEEEEIATPPPPPPPKKE
Position: 191-208
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 40
Chemical type: Peptide from protein
Sequence: IATPPPPPPPKKETKPEP
Position: 196-213
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 40
Chemical type: Peptide from protein
Sequence: IATPPPPPPPKKETKPEP
Position: 196-213
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 40
Chemical type: Peptide from protein
Sequence: IATPPPPPPPKKETKPEP
Position: 196-213
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 40
Chemical type: Peptide from protein
Sequence: IATPPPPPPPKKETKPEP
Position: 196-213
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 41
Chemical type: Peptide from protein
Sequence: PPPPPKKETKPEPMEEDL
Position: 201-218
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 41
Chemical type: Peptide from protein
Sequence: PPPPPKKETKPEPMEEDL
Position: 201-218
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 41
Chemical type: Peptide from protein
Sequence: PPPPPKKETKPEPMEEDL
Position: 201-218
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 41
Chemical type: Peptide from protein
Sequence: PPPPPKKETKPEPMEEDL
Position: 201-218
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 42
Chemical type: Peptide from protein
Sequence: KKETKPEPMEEDLPENKK
Position: 206-223
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 42
Chemical type: Peptide from protein
Sequence: KKETKPEPMEEDLPENKK
Position: 206-223
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 42
Chemical type: Peptide from protein
Sequence: KKETKPEPMEEDLPENKK
Position: 206-223
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 42
Chemical type: Peptide from protein
Sequence: KKETKPEPMEEDLPENKK
Position: 206-223
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 43
Chemical type: Peptide from protein
Sequence: PEPMEEDLPENKKQALKE
Position: 211-228
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 43
Chemical type: Peptide from protein
Sequence: PEPMEEDLPENKKQALKE
Position: 211-228
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 43
Chemical type: Peptide from protein
Sequence: PEPMEEDLPENKKQALKE
Position: 211-228
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 43
Chemical type: Peptide from protein
Sequence: PEPMEEDLPENKKQALKE
Position: 211-228
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 45
Chemical type: Peptide from protein
Sequence: NKKQALKEKELGNDAYKK
Position: 221-238
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 45
Chemical type: Peptide from protein
Sequence: NKKQALKEKELGNDAYKK
Position: 221-238
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 45
Chemical type: Peptide from protein
Sequence: NKKQALKEKELGNDAYKK
Position: 221-238
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 45
Chemical type: Peptide from protein
Sequence: NKKQALKEKELGNDAYKK
Position: 221-238
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 46
Chemical type: Peptide from protein
Sequence: LKEKELGNDAYKKKDFDT
Position: 226-243
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 46
Chemical type: Peptide from protein
Sequence: LKEKELGNDAYKKKDFDT
Position: 226-243
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 46
Chemical type: Peptide from protein
Sequence: LKEKELGNDAYKKKDFDT
Position: 226-243
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 46
Chemical type: Peptide from protein
Sequence: LKEKELGNDAYKKKDFDT
Position: 226-243
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 47
Chemical type: Peptide from protein
Sequence: LGNDAYKKKDFDTALKHY
Position: 231-248
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 47
Chemical type: Peptide from protein
Sequence: LGNDAYKKKDFDTALKHY
Position: 231-248
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 47
Chemical type: Peptide from protein
Sequence: LGNDAYKKKDFDTALKHY
Position: 231-248
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 47
Chemical type: Peptide from protein
Sequence: LGNDAYKKKDFDTALKHY
Position: 231-248
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 48
Chemical type: Peptide from protein
Sequence: YKKKDFDTALKHYDKAKE
Position: 236-253
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 48
Chemical type: Peptide from protein
Sequence: YKKKDFDTALKHYDKAKE
Position: 236-253
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 48
Chemical type: Peptide from protein
Sequence: YKKKDFDTALKHYDKAKE
Position: 236-253
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 48
Chemical type: Peptide from protein
Sequence: YKKKDFDTALKHYDKAKE
Position: 236-253
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 49
Chemical type: Peptide from protein
Sequence: FDTALKHYDKAKELDPTN
Position: 241-258
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Negative

Epitope: STIP1 peptide 49
Chemical type: Peptide from protein
Sequence: FDTALKHYDKAKELDPTN
Position: 241-258
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 peptide 49
Chemical type: Peptide from protein
Sequence: FDTALKHYDKAKELDPTN
Position: 241-258
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 49
Chemical type: Peptide from protein
Sequence: FDTALKHYDKAKELDPTN
Position: 241-258
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 51
Chemical type: Peptide from protein
Sequence: AKELDPTNMTYITNQAAV
Position: 251-268
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 51
Chemical type: Peptide from protein
Sequence: AKELDPTNMTYITNQAAV
Position: 251-268
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 52
Chemical type: Peptide from protein
Sequence: PTNMTYITNQAAVYFEKG
Position: 256-273
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 52
Chemical type: Peptide from protein
Sequence: PTNMTYITNQAAVYFEKG
Position: 256-273
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 53
Chemical type: Peptide from protein
Sequence: YITNQAAVYFEKGDYNKC
Position: 261-278
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 53
Chemical type: Peptide from protein
Sequence: YITNQAAVYFEKGDYNKC
Position: 261-278
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 54
Chemical type: Peptide from protein
Sequence: AAVYFEKGDYNKCRELCE
Position: 266-283
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 54
Chemical type: Peptide from protein
Sequence: AAVYFEKGDYNKCRELCE
Position: 266-283
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 55
Chemical type: Peptide from protein
Sequence: EKGDYNKCRELCEKAIEV
Position: 271-288
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 peptide 55
Chemical type: Peptide from protein
Sequence: EKGDYNKCRELCEKAIEV
Position: 271-288
Source molecule (GenBank): P31948.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: STIP1 PD core epitope I
Chemical type: Peptide from protein
Sequence: ELKEKGN
Position: 6-12
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 PD core epitope II
Chemical type: Peptide from protein
Sequence: LGSMDEEEE
Position: 187-195
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 PD core epitope III
Chemical type: Peptide from protein
Sequence: TKPEPMEEDL
Position: 209-218
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive

Epitope: STIP1 PD core epitope IV
Chemical type: Peptide from protein
Sequence: LKEKELGNDAYKK
Position: 226-238
Source molecule (GenBank): P31948.1
Assay category: BCell
Result: Positive