Reference: Yingxin Xian; Haixia Xu; Yifang Gao; Jinhua Yan; Jing Lv; Wenqian Ren; Qianwen Huang; Ziyu Jiang; Fen Xu; Bin Yao; Jianping Weng. "A pilot study of preproinsulin peptides reactivity in Chinese patients with type 1 diabetes." Diabetes/metabolism research and reviews (2020).

Epitope: B9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C19-A3
Chemical type: Peptide from protein
Sequence: GSLQPLALEGSLQKRGIV
Position: 75-92
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C19-A3
Chemical type: Peptide from protein
Sequence: GSLQPLALEGSLQKRGIV
Position: 75-92
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B1-16
Chemical type: Peptide from protein
Sequence: FVNQHLCGSHLVEALY
Position: 25-40
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B1-16
Chemical type: Peptide from protein
Sequence: FVNQHLCGSHLVEALY
Position: 25-40
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B10-24
Chemical type: Peptide from protein
Sequence: HLVEALYLVCGERGF
Position: 34-48
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B10-24
Chemical type: Peptide from protein
Sequence: HLVEALYLVCGERGF
Position: 34-48
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B30-C13
Chemical type: Peptide from protein
Sequence: TRREAEDLQVGQVELG
Position: 54-69
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B30-C13
Chemical type: Peptide from protein
Sequence: TRREAEDLQVGQVELG
Position: 54-69
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L9‐24
Chemical type: Peptide from protein
Sequence: PLLALLALWGPDPAAA
Position: 9-24
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L9‐24
Chemical type: Peptide from protein
Sequence: PLLALLALWGPDPAAA
Position: 9-24
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L17‐B8
Chemical type: Peptide from protein
Sequence: WGPDPAAAFVNQHLCG
Position: 17-32
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: L17‐B8
Chemical type: Peptide from protein
Sequence: WGPDPAAAFVNQHLCG
Position: 17-32
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B1‐16
Chemical type: Peptide from protein
Sequence: FVNQHLCGSHLVEALY
Position: 25-40
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B1‐16
Chemical type: Peptide from protein
Sequence: FVNQHLCGSHLVEALY
Position: 25-40
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B9‐24
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERGF
Position: 33-48
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B9‐24
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERGF
Position: 33-48
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B17‐R56
Chemical type: Peptide from protein
Sequence: LVCGERGFFYTPKTRR
Position: 41-56
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B17‐R56
Chemical type: Peptide from protein
Sequence: LVCGERGFFYTPKTRR
Position: 41-56
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B25‐C8
Chemical type: Peptide from protein
Sequence: FYTPKTRREAEDLQVG
Position: 49-64
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B25‐C8
Chemical type: Peptide from protein
Sequence: FYTPKTRREAEDLQVG
Position: 49-64
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C1‐16
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVELGGGP
Position: 57-72
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C1‐16
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVELGGGP
Position: 57-72
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C9‐24
Chemical type: Peptide from protein
Sequence: QVELGGGPGAGSLQPL
Position: 65-80
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C9‐24
Chemical type: Peptide from protein
Sequence: QVELGGGPGAGSLQPL
Position: 65-80
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C17‐K88
Chemical type: Peptide from protein
Sequence: GAGSLQPLALEGSLQK
Position: 73-88
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C17‐K88
Chemical type: Peptide from protein
Sequence: GAGSLQPLALEGSLQK
Position: 73-88
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C25‐A7
Chemical type: Peptide from protein
Sequence: ALEGSLQKRGIVEQCC
Position: 81-96
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: C25‐A7
Chemical type: Peptide from protein
Sequence: ALEGSLQKRGIVEQCC
Position: 81-96
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: R89‐A15
Chemical type: Peptide from protein
Sequence: RGIVEQCCTSICSLYQ
Position: 89-104
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: R89‐A15
Chemical type: Peptide from protein
Sequence: RGIVEQCCTSICSLYQ
Position: 89-104
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A8‐A21
Chemical type: Peptide from protein
Sequence: TSICSLYQLENYCN
Position: 97-110
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
Host:  5-25 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: A8‐A21
Chemical type: Peptide from protein
Sequence: TSICSLYQLENYCN
Position: 97-110
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Negative
MHC allele types: 57 408 417 313 87 413 437 415 436 84 774 94 88 316 515 818 318
Host:  1-55 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo