Reference: Tiziano Gaiotto; Simon E Hufton. "Cross-Neutralising Nanobodies Bind to a Conserved Pocket in the Hemagglutinin Stem Region Identified Using Yeast Display and Deep Mutational Scanning." PloS one (2016).

Epitope: mAb R1a-G6
Chemical type: Discontinuous protein residues
Discontinuous residues: I183, D185, G187
Source molecule (GenBank): ACP44189.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R1a-G6
Chemical type: Discontinuous protein residues
Discontinuous residues: I183, D185, G187
Source molecule (GenBank): ACP44189.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R1a-G6
Chemical type: Discontinuous protein residues
Discontinuous residues: I183, D185, G187
Source molecule (GenBank): ACP44189.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R1a-F5
Chemical type: Discontinuous protein residues
Discontinuous residues: T30, K39
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R1a-F5
Chemical type: Discontinuous protein residues
Discontinuous residues: T30, K39
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R1a-F5
Chemical type: Discontinuous protein residues
Discontinuous residues: T30, K39
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000042
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000031
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00044
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00030
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000090
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000076
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000058
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.35
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.18
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.05
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.08
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.13
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.13
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.1
Host: M juvenile

Epitope: mAb R2b-D9
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0026
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0022
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00018
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000012
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00052
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.84
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.23
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.23
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.15
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.82
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.45
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.21
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00026
Host: M juvenile

Epitope: mAb R1a-B6
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389
Source molecule (GenBank): ACQ55359.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0018
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00017
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00017
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000086
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00045
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0018
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0019
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0017
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.62
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.81
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.21
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.45
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.69
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.39
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.35
Host: M juvenile

Epitope: mAb R1a-A5
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R2b-E8
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, D390, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R2b-E8
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, D390, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0016
Host: M juvenile

Epitope: mAb R2b-E8
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, D390, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00051
Host: M juvenile

Epitope: mAb R2b-E8
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, D390, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.013
Host: M juvenile

Epitope: mAb R2b-E8
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, D390, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00024
Host: M juvenile

Epitope: mAb R2b-E8
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, D390, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00035
Host: M juvenile

Epitope: mAb R2b-E8
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, D390, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R2b-E8
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, D390, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.64
Host: M juvenile

Epitope: mAb R2b-E8
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, D390, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.96
Host: M juvenile

Epitope: mAb R2b-E8
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, D390, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.8
Host: M juvenile

Epitope: mAb R2b-E8
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, D390, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 374.0
Host: M juvenile

Epitope: mAb R2b-E8
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, D390, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.65
Host: M juvenile

Epitope: mAb R2b-E8
Chemical type: Discontinuous protein residues
Discontinuous residues: G364, W365, I389, D390, I392, V396, N397
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00013
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000083
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00039
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00014
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00018
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0010
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.12
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.13
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.5
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.16
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.36
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.66
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.07
Host: M juvenile

Epitope: mAb R2a-G8
Chemical type: Discontinuous protein residues
Discontinuous residues: M361, D363, G364, W365, Y378, I389, I392
Source molecule (GenBank): AFM72832.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00019
Host: M juvenile

Epitope: mAb FC41
Chemical type: Region on multi-chain protein
Discontinuous residues: A: G319; B: M17, G20, W21, G23, T41, Q42, I45, I48
Source molecule (GenBank): 0704243A
Assay category: BCell
Result: Positive