Reference: María G Alvarez; Miriam Postan; D Brent Weatherly; María C Albareda; John Sidney; Alessandro Sette; Carina Olivera; Alejandro H Armenti; Rick L Tarleton; Susana A Laucella. "HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease." PLoS neglected tropical diseases (2008).

Epitope: Ts 48
Chemical type: Peptide from protein
Sequence: FANYNFTLV
Position: 535-543
Source molecule (GenBank): BAA31361.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 48
Chemical type: Peptide from protein
Sequence: FANYNFTLV
Position: 535-543
Source molecule (GenBank): BAA31361.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 0.47

Epitope: Ts 3
Chemical type: Peptide from protein
Sequence: GLLPSLLLLL
Position: 39-48
Source molecule (GenBank): EAN80935.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 3
Chemical type: Peptide from protein
Sequence: GLLPSLLLLL
Position: 39-48
Source molecule (GenBank): EAN80935.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 3.1

Epitope: Ts 13
Chemical type: Peptide from protein
Sequence: LLGLWGTAAL
Position: 188-197
Source molecule (GenBank): EAN80945.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 13
Chemical type: Peptide from protein
Sequence: LLGLWGTAAL
Position: 188-197
Source molecule (GenBank): EAN80945.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 499.0

Epitope: Ts 46
Chemical type: Peptide from protein
Sequence: FANHNFTLV
Position: 572-580
Source molecule (GenBank): EAN82291.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 46
Chemical type: Peptide from protein
Sequence: FANHNFTLV
Position: 572-580
Source molecule (GenBank): EAN82291.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 119.0

Epitope: Ts 44
Chemical type: Peptide from protein
Sequence: FANYKFTLV
Position: 379-387
Source molecule (GenBank): EAN81560.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 44
Chemical type: Peptide from protein
Sequence: FANYKFTLV
Position: 379-387
Source molecule (GenBank): EAN81560.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 49.0

Epitope: Ts 43
Chemical type: Peptide from protein
Sequence: FANNKFTLV
Position: 179-187
Source molecule (GenBank): EAN80946.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 43
Chemical type: Peptide from protein
Sequence: FANNKFTLV
Position: 179-187
Source molecule (GenBank): EAN80946.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 116.0

Epitope: Ts 58
Chemical type: Peptide from protein
Sequence: RVSRPTTVV
Position: 181-189
Source molecule (GenBank): EAN82076.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 58
Chemical type: Peptide from protein
Sequence: RVSRPTTVV
Position: 181-189
Source molecule (GenBank): EAN82076.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 2487.0

Epitope: Ts 66
Chemical type: Peptide from protein
Sequence: DVSRPTAVV
Position: 121-129
Source molecule (GenBank): EAN81657.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 66
Chemical type: Peptide from protein
Sequence: DVSRPTAVV
Position: 121-129
Source molecule (GenBank): EAN81657.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: Ts 37
Chemical type: Peptide from protein
Sequence: FVNHRFTLV
Position: 32-40
Source molecule (GenBank): EAN80731.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 37
Chemical type: Peptide from protein
Sequence: FVNHRFTLV
Position: 32-40
Source molecule (GenBank): EAN80731.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 304.0

Epitope: Ts 51
Chemical type: Peptide from protein
Sequence: FANYNFTLL
Position: 621-629
Source molecule (GenBank): EAN84580.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 51
Chemical type: Peptide from protein
Sequence: FANYNFTLL
Position: 621-629
Source molecule (GenBank): EAN84580.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1499.0

Epitope: Ts 52
Chemical type: Peptide from protein
Sequence: ELLRPTTLV
Position: 168-176
Source molecule (GenBank): EAN81972.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 52
Chemical type: Peptide from protein
Sequence: ELLRPTTLV
Position: 168-176
Source molecule (GenBank): EAN81972.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 2407.0

Epitope: Ts 49
Chemical type: Peptide from protein
Sequence: FANNEFTLV
Position: 265-273
Source molecule (GenBank): EAN81456.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 49
Chemical type: Peptide from protein
Sequence: FANNEFTLV
Position: 265-273
Source molecule (GenBank): EAN81456.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 47.0

Epitope: Ts 68
Chemical type: Peptide from protein
Sequence: FTNNKFTLS
Position: 532-540
Source molecule (GenBank): EAN81686.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 68
Chemical type: Peptide from protein
Sequence: FTNNKFTLS
Position: 532-540
Source molecule (GenBank): EAN81686.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 50000.0

Epitope: Ts 35
Chemical type: Peptide from protein
Sequence: FVSCDFTIV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 35
Chemical type: Peptide from protein
Sequence: FVSCDFTIV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 30.0

Epitope: Ts 24
Chemical type: Peptide from protein
Sequence: FLSHDFTLV
Position: 551-559
Source molecule (GenBank): EAN82636.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 24
Chemical type: Peptide from protein
Sequence: FLSHDFTLV
Position: 551-559
Source molecule (GenBank): EAN82636.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 0.46

Epitope: Ts 6
Chemical type: Peptide from protein
Sequence: LLGLWGLATA
Position: 743-752
Source molecule (GenBank): P18269.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 6
Chemical type: Peptide from protein
Sequence: LLGLWGLATA
Position: 743-752
Source molecule (GenBank): P18269.2
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 24.0

Epitope: Ts 4
Chemical type: Peptide from protein
Sequence: RLLPSLLLLL
Position: 123-132
Source molecule (GenBank): EAN81345.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 4
Chemical type: Peptide from protein
Sequence: RLLPSLLLLL
Position: 123-132
Source molecule (GenBank): EAN81345.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 0.8

Epitope: Ts 28
Chemical type: Peptide from protein
Sequence: FVNYDFALV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 28
Chemical type: Peptide from protein
Sequence: FVNYDFALV
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 79.0

Epitope: Ts 32
Chemical type: Peptide from protein
Sequence: FANCNFTLV
Position: 570-578
Source molecule (GenBank): EAN88532.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 32
Chemical type: Peptide from protein
Sequence: FANCNFTLV
Position: 570-578
Source molecule (GenBank): EAN88532.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 79.0

Epitope: Ts 50
Chemical type: Peptide from protein
Sequence: FVNYDFTIV
Position: 513-521
Source molecule (GenBank): EAN98330.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 50
Chemical type: Peptide from protein
Sequence: FVNYDFTIV
Position: 513-521
Source molecule (GenBank): EAN98330.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 77.0

Epitope: Ts 47
Chemical type: Peptide from protein
Sequence: FVDYNFSLV
Position: 9-17
Source molecule (GenBank): EAN80886.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 47
Chemical type: Peptide from protein
Sequence: FVDYNFSLV
Position: 9-17
Source molecule (GenBank): EAN80886.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1.1

Epitope: Ts 45
Chemical type: Peptide from protein
Sequence: FVNYNFTLV
Position: 554-562
Source molecule (GenBank): EAN89832.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 45
Chemical type: Peptide from protein
Sequence: FVNYNFTLV
Position: 554-562
Source molecule (GenBank): EAN89832.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 0.25

Epitope: Ts 56
Chemical type: Peptide from protein
Sequence: IANYNFTLV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 56
Chemical type: Peptide from protein
Sequence: IANYNFTLV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 29640.0

Epitope: Ts 27
Chemical type: Peptide from protein
Sequence: FLSHNFTLVF
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 27
Chemical type: Peptide from protein
Sequence: FLSHNFTLVF
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 0.61

Epitope: Ts 26
Chemical type: Peptide from protein
Sequence: SLSHYFTLVF
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 26
Chemical type: Peptide from protein
Sequence: SLSHYFTLVF
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1.6

Epitope: Ts 34
Chemical type: Peptide from protein
Sequence: FANHDFTLV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts 34
Chemical type: Peptide from protein
Sequence: FANHDFTLV
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 101.0

Epitope: Ts (VTD)
Chemical type: Peptide from protein
Sequence: VTDNNRSFY
Position: 394-402
Source molecule (GenBank): EAN82716.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (LWL)
Chemical type: Peptide from protein
Sequence: LWLTDNTHI
Position: 168-176
Source molecule (GenBank): EAN80840.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (LLL)
Chemical type: Peptide from protein
Sequence: LLLGLWGFA
Position: 264-272
Source molecule (GenBank): EAN80725.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (YNF)
Chemical type: Peptide from protein
Sequence: YNFTLVATV
Position: 343-351
Source molecule (GenBank): EAN80840.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (FTS)
Chemical type: Peptide from protein
Sequence: FTSAVLLLL
Position: 44-52
Source molecule (GenBank): EAN82835.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (MLV)
Chemical type: Peptide from protein
Sequence: MLVTLPVYS
Position: 385-393
Source molecule (GenBank): EAN81042.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (NVM)
Chemical type: Peptide from protein
Sequence: NVMLVTLPV
Position: 141-149
Source molecule (GenBank): EAN80840.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (FVS)
Chemical type: Peptide from protein
Sequence: FVSPSLVSA
Position: 90-98
Source molecule (GenBank): EAN82716.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (ALS)
Chemical type: Peptide from protein
Sequence: ALSSSLGNV
Position: 715-723
Source molecule (GenBank): EAN81705.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (HLF)
Chemical type: Peptide from protein
Sequence: HLFYSAVLL
Position: 4-12
Source molecule (GenBank): EAN81657.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (FLY)
Chemical type: Peptide from protein
Sequence: FLYNRPLNS
Position: 209-217
Source molecule (GenBank): EAN80725.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (LLLL)
Chemical type: Peptide from protein
Sequence: LLLLVVMMCC
Position: 49-58
Source molecule (GenBank): EAN82076.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (SIP)
Chemical type: Peptide from protein
Sequence: SIPTAGLVAV
Position: 18-27
Source molecule (GenBank): EAN80725.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (RVL)
Chemical type: Peptide from protein
Sequence: RVLLLLLLGL
Position: 726-735
Source molecule (GenBank): EAN82235.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (MLS)
Chemical type: Peptide from protein
Sequence: MLSRVAAVK
Position: 1-9
Source molecule (GenBank): EAN81042.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (FTL)
Chemical type: Peptide from protein
Sequence: FTLVATVSI
Position: 345-353
Source molecule (GenBank): EAN80840.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (AVA)
Chemical type: Peptide from protein
Sequence: AVAEAQCKK
Position: 105-113
Source molecule (GenBank): EAN88532.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (VAL)
Chemical type: Peptide from protein
Sequence: VALMLQGNK
Position: 157-165
Source molecule (GenBank): EAN80918.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (DVA)
Chemical type: Peptide from protein
Sequence: DVAASSLLY
Position: 426-434
Source molecule (GenBank): EAN81042.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (ITA)
Chemical type: Peptide from protein
Sequence: ITATIEGRK
Position: 380-388
Source molecule (GenBank): EAN81650.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (IYM)
Chemical type: Peptide from protein
Sequence: IYMLVGKYS
Position: 134-142
Source molecule (GenBank): EAN81657.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Ts (GVI)
Chemical type: Peptide from protein
Sequence: GVIAAFAEGH
Position: 117-126
Source molecule (GenBank): EAN82636.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo