Reference: Yanli Yang; Sherry H Yeh; Shravan Madireddi; Wadim L Matochko; Chen Gu; Patricia Pacheco Sanchez; Mark Ultsch; Gladys De Leon Boenig; Seth F Harris; Brandon Leonard; Suzie J Scales; Jing W Zhu; Erin Christensen; Julie Q Hang; Randall J Brezski; Scot Marsters; Avi Ashkenazi; Siddharth Sukumaran; Henry Chiu; Rafael Cubas; Jeong M Kim; Greg A Lazar. "Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members." mAbs (2019).

Epitope: Epitope of Fab1 on OX40 (TNFRSF4)
Chemical type: Discontinuous protein residues
Discontinuous residues: N88, R90, S91, Q114, L116, S118, Y119, V123, D124, C125, A126, P127, C128, P129, P130, H132, A140, C141, K142, P143
Source molecule (GenBank): P43489.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab1 on OX40 (TNFRSF4)
Chemical type: Discontinuous protein residues
Discontinuous residues: N88, R90, S91, Q114, L116, S118, Y119, V123, D124, C125, A126, P127, C128, P129, P130, H132, A140, C141, K142, P143
Source molecule (GenBank): P43489.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.45

Epitope: Epitope of Fab1 on OX40 (TNFRSF4)
Chemical type: Discontinuous protein residues
Discontinuous residues: N88, R90, S91, Q114, L116, S118, Y119, V123, D124, C125, A126, P127, C128, P129, P130, H132, A140, C141, K142, P143
Source molecule (GenBank): P43489.1
Assay category: BCell
Result: Negative

Epitope: Epitope of Fab1 on OX40 (TNFRSF4)
Chemical type: Discontinuous protein residues
Discontinuous residues: N88, R90, S91, Q114, L116, S118, Y119, V123, D124, C125, A126, P127, C128, P129, P130, H132, A140, C141, K142, P143
Source molecule (GenBank): P43489.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab1 on OX40 (TNFRSF4)
Chemical type: Discontinuous protein residues
Discontinuous residues: N88, R90, S91, Q114, L116, S118, Y119, V123, D124, C125, A126, P127, C128, P129, P130, H132, A140, C141, K142, P143
Source molecule (GenBank): P43489.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.25

Epitope: Epitope of Fab1 on OX40 (TNFRSF4)
Chemical type: Discontinuous protein residues
Discontinuous residues: N88, R90, S91, Q114, L116, S118, Y119, V123, D124, C125, A126, P127, C128, P129, P130, H132, A140, C141, K142, P143
Source molecule (GenBank): P43489.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.77

Epitope: Epitope of Fab2 on OX40 (TNFRSF4)
Chemical type: Discontinuous protein residues
Discontinuous residues: G68, P69, G70, F71, P83, W86, C87, N88, L89, R90, R95, K96, Q97, L98
Source molecule (GenBank): P43489.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.5

Epitope: Epitope of Fab2 on OX40 (TNFRSF4)
Chemical type: Discontinuous protein residues
Discontinuous residues: G68, P69, G70, F71, P83, W86, C87, N88, L89, R90, R95, K96, Q97, L98
Source molecule (GenBank): P43489.1
Assay category: BCell
Result: Negative

Epitope: Epitope of Fab2 on OX40 (TNFRSF4)
Chemical type: Discontinuous protein residues
Discontinuous residues: G68, P69, G70, F71, P83, W86, C87, N88, L89, R90, R95, K96, Q97, L98
Source molecule (GenBank): P43489.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab2 on OX40 (TNFRSF4)
Chemical type: Discontinuous protein residues
Discontinuous residues: G68, P69, G70, F71, P83, W86, C87, N88, L89, R90, R95, K96, Q97, L98
Source molecule (GenBank): P43489.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.77

Epitope: Epitope of Fab2 on OX40 (TNFRSF4)
Chemical type: Discontinuous protein residues
Discontinuous residues: G68, P69, G70, F71, P83, W86, C87, N88, L89, R90, R95, K96, Q97, L98
Source molecule (GenBank): P43489.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.1