Reference: Kellie N Smith; Nicolas J Llosa; Tricia R Cottrell; Nicholas Siegel; Hongni Fan; Prerna Suri; Hok Yee Chan; Haidan Guo; Teniola Oke; Anas H Awan; Franco Verde; Ludmila Danilova; Valsamo Anagnostou; Ada J Tam; Brandon S Luber; Bjarne R Bartlett; Laveet K Aulakh; John-William Sidhom; Qingfeng Zhu; Cynthia L Sears; Leslie Cope; William H Sharfman; Elizabeth D Thompson; Joanne Riemer; Kristen A Marrone; Jarushka Naidoo; Victor E Velculescu; Patrick M Forde; Bert Vogelstein; Kenneth W Kinzler; Nickolas Papadopoulos; Jennifer N Durham; Hao Wang; Dung T Le; Sune Justesen; Janis M Taube; Luis A Diaz; Julie R Brahmer; Drew M Pardoll; Robert A Anders; Franck Housseau. "Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1." Journal for immunotherapy of cancer (2019).

Epitope: LUAD 3
Chemical type: Peptide, no natural source
Sequence: SSCFERLY
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 4
Chemical type: Peptide, no natural source
Sequence: PTSLEVVSY
Assay category: TCell
Result: Negative
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 5
Chemical type: Peptide, no natural source
Sequence: WSDPLKLTVK
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 6
Chemical type: Peptide, no natural source
Sequence: PSGSKLTFDY
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 7
Chemical type: Peptide, no natural source
Sequence: SGSKLTFDY
Assay category: TCell
Result: Negative
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 8
Chemical type: Peptide, no natural source
Sequence: CSSCFERLYF
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 9
Chemical type: Peptide, no natural source
Sequence: TSLEVVSY
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 11
Chemical type: Peptide, no natural source
Sequence: TVCSSCFERLY
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 12
Chemical type: Peptide, no natural source
Sequence: GSKLTFDY
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 22
Chemical type: Peptide, no natural source
Sequence: YMKATATV
Assay category: TCell
Result: Negative
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 23
Chemical type: Peptide, no natural source
Sequence: FIYIFHTL
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 24
Chemical type: Peptide, no natural source
Sequence: SLCAFNPNPHL
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 26
Chemical type: Peptide, no natural source
Sequence: IIFLHEDLTV
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 26
Chemical type: Peptide, no natural source
Sequence: IIFLHEDLTV
Assay category: MhcBinding
Result: Positive-Low

Epitope: LUAD 27
Chemical type: Peptide, no natural source
Sequence: LMFALAKGRRA
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 28
Chemical type: Peptide, no natural source
Sequence: SLQTPFPWPPM
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 29
Chemical type: Peptide, no natural source
Sequence: KLVPSGSKL
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 30
Chemical type: Peptide, no natural source
Sequence: FTQRWRVSHV
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 31
Chemical type: Peptide, no natural source
Sequence: NIIFLHEDLTV
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 32
Chemical type: Peptide, no natural source
Sequence: FLLPAPYWAR
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 36
Chemical type: Peptide, no natural source
Sequence: ELGHPYLWVL
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 41
Chemical type: Peptide, no natural source
Sequence: CEVSNPVSSNW
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 41
Chemical type: Peptide, no natural source
Sequence: CEVSNPVSSNW
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 45
Chemical type: Peptide, no natural source
Sequence: LEVVSYAPFTL
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 45
Chemical type: Peptide, no natural source
Sequence: LEVVSYAPFTL
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 56
Chemical type: Peptide, no natural source
Sequence: SHWAAQVI
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 56
Chemical type: Peptide, no natural source
Sequence: SHWAAQVI
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LUAD 61
Chemical type: Peptide, no natural source
Sequence: RRWNFIYIF
Assay category: TCell
Result: Positive
Host: F 76 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 1
Chemical type: Peptide, no natural source
Sequence: YYANAYIF
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 7
Chemical type: Peptide, no natural source
Sequence: RWAQALYDF
Assay category: TCell
Result: Positive
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 8
Chemical type: Peptide, no natural source
Sequence: KYIKTWRPRYF
Assay category: TCell
Result: Positive
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 8
Chemical type: Peptide, no natural source
Sequence: KYIKTWRPRYF
Assay category: MhcBinding
Result: Positive

Epitope: CRC 13
Chemical type: Peptide, no natural source
Sequence: MTWPGENTNLF
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 14
Chemical type: Peptide, no natural source
Sequence: HTADIKESAAY
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 16
Chemical type: Peptide, no natural source
Sequence: EAHDALHYF
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 17
Chemical type: Peptide, no natural source
Sequence: MTQFHFLSWY
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 18
Chemical type: Peptide, no natural source
Sequence: DSIDRICARF
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 19
Chemical type: Peptide, no natural source
Sequence: SHDIQHVL
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 20
Chemical type: Peptide, no natural source
Sequence: THWEQLDYEV
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 21
Chemical type: Peptide, no natural source
Sequence: EHLHAWISIL
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 22
Chemical type: Peptide, no natural source
Sequence: SHTLWLHL
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 23
Chemical type: Peptide, no natural source
Sequence: WRSSLYFL
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 24
Chemical type: Peptide, no natural source
Sequence: GEFGLWRSSLY
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 25
Chemical type: Peptide, no natural source
Sequence: SENRSLRF
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 27
Chemical type: Peptide, no natural source
Sequence: QEVHRFVVCEY
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CRC 28
Chemical type: Peptide, no natural source
Sequence: YEVQFTSSRKF
Assay category: TCell
Result: Negative
Host: F 69 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B-raf (581-590)
Chemical type: Peptide from protein
Sequence: NIFLHEDLTV
Position: 581-590
Source molecule (GenBank): P15056.4
Assay category: MhcBinding
Result: Negative

Epitope: Akt 1(17-27)
Chemical type: Peptide from protein
Sequence: EYIKTWRPRYF
Position: 17-27
Source molecule (GenBank): P31749.2
Assay category: MhcBinding
Result: Positive