Reference: Morgan S A Gilman; Syed M Moin; Vicente Mas; Man Chen; Nita K Patel; Kari Kramer; Qing Zhu; Stephanie C Kabeche; Azad Kumar; Concepción Palomo; Tim Beaumont; Ulrich Baxa; Nancy D Ulbrandt; José A Melero; Barney S Graham; Jason S McLellan. "Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein." PLoS pathogens (2015).

Epitope: Epitope of Fab AM14 on RSV prefusion F glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N426, N428, R429, I432, K445, G446, E463, K465; C: L160, E161, S182, N183, G184
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab AM14 on RSV prefusion F glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N426, N428, R429, I432, K445, G446, E463, K465; C: L160, E161, S182, N183, G184
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.63

Epitope: Epitope of Fab AM14 on RSV prefusion F glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N426, N428, R429, I432, K445, G446, E463, K465; C: L160, E161, S182, N183, G184
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab AM14 on RSV prefusion F glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N426, N428, R429, I432, K445, G446, E463, K465; C: L160, E161, S182, N183, G184
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab AM14 on RSV prefusion F glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N426, N428, R429, I432, K445, G446, E463, K465; C: L160, E161, S182, N183, G184
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Quantitative measurement: 18700000

Epitope: Epitope of Fab AM14 on RSV prefusion F glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N426, N428, R429, I432, K445, G446, E463, K465; C: L160, E161, S182, N183, G184
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab AM14 on RSV prefusion F glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N426, N428, R429, I432, K445, G446, E463, K465; C: L160, E161, S182, N183, G184
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab AM14 on RSV prefusion F glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N426, N428, R429, I432, K445, G446, E463, K465; C: L160, E161, S182, N183, G184
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab AM14 on RSV prefusion F glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N426, N428, R429, I432, K445, G446, E463, K465; C: L160, E161, S182, N183, G184
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Quantitative measurement: 5.5

Epitope: Epitope of Fab AM14 on RSV prefusion F glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N426, N428, R429, I432, K445, G446, E463, K465; C: L160, E161, S182, N183, G184
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.18

Epitope: Epitope of Fab AM14 on RSV prefusion F glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N426, N428, R429, I432, K445, G446, E463, K465; C: L160, E161, S182, N183, G184
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab AM14 on RSV prefusion F glycoprotein
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N426, N428, R429, I432, K445, G446, E463, K465; C: L160, E161, S182, N183, G184
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0034

Epitope: Epitope of Fab Motavizumab on RSV fusion F glycoprotein
Chemical type: Discontinuous protein residues
Discontinuous residues: L258, S259, N262, D263, T267, N268, D269, K271, K272, S275, N276, D310, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Quantitative measurement: 5.5
Host: F

Epitope: Epitope of Fab Motavizumab on RSV fusion F glycoprotein
Chemical type: Discontinuous protein residues
Discontinuous residues: L258, S259, N262, D263, T267, N268, D269, K271, K272, S275, N276, D310, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of Fab Motavizumab on RSV fusion F glycoprotein
Chemical type: Discontinuous protein residues
Discontinuous residues: L258, S259, N262, D263, T267, N268, D269, K271, K272, S275, N276, D310, R364
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of Fab D25 on RSV fusion glycoprotein
Chemical type: Discontinuous protein residues
Discontinuous residues: N63, K65, E66, K68, K196, N197, Y198, I199, D200, K201, Q202, L203, L204, P205, I206, V207, N208, K209, Q210
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.07

Epitope: Epitope of Fab D25 on RSV fusion glycoprotein
Chemical type: Discontinuous protein residues
Discontinuous residues: N63, K65, E66, K68, K196, N197, Y198, I199, D200, K201, Q202, L203, L204, P205, I206, V207, N208, K209, Q210
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.9

Epitope: Epitope of Fab D25 on RSV fusion glycoprotein
Chemical type: Discontinuous protein residues
Discontinuous residues: N63, K65, E66, K68, K196, N197, Y198, I199, D200, K201, Q202, L203, L204, P205, I206, V207, N208, K209, Q210
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1350000.0

Epitope: Epitope of Fab D25 on RSV fusion glycoprotein
Chemical type: Discontinuous protein residues
Discontinuous residues: N63, K65, E66, K68, K196, N197, Y198, I199, D200, K201, Q202, L203, L204, P205, I206, V207, N208, K209, Q210
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000965

Epitope: Epitope of mAb 101F on RSV fusion F glycoprotein
Chemical type: Peptide from protein
Sequence: KNRGIIKTFSN
Position: 427-437
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of ME8 on RSV fusion F glycoprotein
Chemical type: Discontinuous protein residues
Discontinuous residues: T50, L305, G307, I309, D310
Source molecule (GenBank): P03420.1
Assay category: BCell
Result: Positive