Reference: Jonathan C Tong; Mark A Myers; Ian R Mackay; Paul Z Zimmet; Merrill J Rowley. "The PEVKEK region of the pyridoxal phosphate binding domain of GAD65 expresses a dominant B cell epitope for type 1 diabetes sera." Annals of the New York Academy of Sciences (2002).

Epitope: Hu HCgp39 263-275
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Hu HCgp39 263-275
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Hu HCgp39 263-275
Chemical type: Peptide from protein
Sequence: RSFTLASSETGVG
Position: 263-275
Source molecule (GenBank): P36222.2
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 440.0

Epitope: Hu PSA 64-78
Chemical type: Peptide from protein
Sequence: QVFQVSHSFPHPLYD
Position: 88-102
Source molecule (GenBank): P07288.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Hu PSA 64-78
Chemical type: Peptide from protein
Sequence: QVFQVSHSFPHPLYD
Position: 88-102
Source molecule (GenBank): P07288.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Hu PSA 64-78
Chemical type: Peptide from protein
Sequence: QVFQVSHSFPHPLYD
Position: 88-102
Source molecule (GenBank): P07288.2
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 2300.0

Epitope: Hu GAD65 552-572
Chemical type: Peptide from protein
Sequence: DKVNFFRMVISNPAATHQDID
Position: 552-572
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Hu GAD65 552-572
Chemical type: Peptide from protein
Sequence: DKVNFFRMVISNPAATHQDID
Position: 552-572
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Hu GAD65 552-572
Chemical type: Peptide from protein
Sequence: DKVNFFRMVISNPAATHQDID
Position: 552-572
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: Hu GAD65 552-572
Chemical type: Peptide from protein
Sequence: DKVNFFRMVISNPAATHQDID
Position: 552-572
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Hu GAD65 552-572
Chemical type: Peptide from protein
Sequence: DKVNFFRMVISNPAATHQDID
Position: 552-572
Source molecule (GenBank): Q05329.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 70.0

Epitope: Hu GAD 65 (274-286)
Chemical type: Peptide from protein
Sequence: IAFTSEHSHFSLK
Position: 274-286
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Hu GAD 65 (274-286)
Chemical type: Peptide from protein
Sequence: IAFTSEHSHFSLK
Position: 274-286
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Hu GAD 65 (274-286)
Chemical type: Peptide from protein
Sequence: IAFTSEHSHFSLK
Position: 274-286
Source molecule (GenBank): Q05329.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 5500.0

Epitope: Hu GAD65 555-567
Chemical type: Peptide from protein
Sequence: NFFRMVISNPAAT
Position: 555-567
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HA peptide 306-318
Chemical type: Peptide from protein
Sequence: PKYVKQNTLKLAT
Position: 306-318
Source molecule (GenBank): AAA43143.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 1400.0