Reference: Yu Sawada; Hiroyuki Komori; Yoshiyuki Tsunoda; Manami Shimomura; Mari Takahashi; Hideo Baba; Masaaki Ito; Norio Saito; Hiroyuki Kuwano; Itaru Endo; Yasuharu Nishimura; Tetsuya Nakatsura. "Identification of HLA-A2 or HLA-A24-restricted CTL epitopes for potential HSP105-targeted immunotherapy in colorectal cancer." Oncology reports (2014).

Epitope: HSP105 A2-4
Chemical type: Peptide from protein
Sequence: MLLTKLKET
Position: 120-128
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A2-5
Chemical type: Peptide from protein
Sequence: VISVPSFFT
Position: 141-149
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A2-6
Chemical type: Peptide from protein
Sequence: SVLDAAQIV
Position: 155-163
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A2-9
Chemical type: Peptide from protein
Sequence: DMGHSAFQV
Position: 202-210
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A2-10
Chemical type: Peptide from protein
Sequence: VLGTAFDPFL
Position: 222-231
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A2-12
Chemical type: Peptide from protein
Sequence: KLMSSNSTDL
Position: 275-284
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HSP105 A2-12
Chemical type: Peptide from protein
Sequence: KLMSSNSTDL
Position: 275-284
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HSP105 A2-12
Chemical type: Peptide from protein
Sequence: KLMSSNSTDL
Position: 275-284
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive
Host:  51-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HSP105 A2-12
Chemical type: Peptide from protein
Sequence: KLMSSNSTDL
Position: 275-284
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HSP105 A2-12
Chemical type: Peptide from protein
Sequence: KLMSSNSTDL
Position: 275-284
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A2-13
Chemical type: Peptide from protein
Sequence: LMSSNSTDL
Position: 276-284
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A2-14
Chemical type: Peptide from protein
Sequence: KMNRSQFEEL
Position: 300-309
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A2-15
Chemical type: Peptide from protein
Sequence: SQFEELCAEL
Position: 304-313
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A2-19
Chemical type: Peptide from protein
Sequence: FLRRGPFEL
Position: 434-442
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A2-20
Chemical type: Peptide from protein
Sequence: KIGRFVVQNT
Assay category: TCell
Result: Negative
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A2-25
Chemical type: Peptide from protein
Sequence: LLTETEDWL
Position: 668-676
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A2-26
Chemical type: Peptide from protein
Sequence: WLYEEGEDQA
Position: 675-684
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A2-29
Chemical type: Peptide from protein
Sequence: EVMEWMNNV
Position: 757-765
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A24-1
Chemical type: Peptide from protein
Sequence: NYGIYKQDL
Position: 180-188
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive
Host:  46-71 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HSP105 A24-1
Chemical type: Peptide from protein
Sequence: NYGIYKQDL
Position: 180-188
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A24-2
Chemical type: Peptide from protein
Sequence: AFNKGKLKVL
Position: 214-223
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A24-3
Chemical type: Peptide from protein
Sequence: KYKLDAKSKI
Position: 251-260
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A24-4
Chemical type: Peptide from protein
Sequence: QFEELCAEL
Position: 305-313
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A24-5
Chemical type: Peptide from protein
Sequence: TFLRRGPFEL
Position: 433-442
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A24-7
Chemical type: Peptide from protein
Sequence: EYVYEFRDKL
Position: 640-649
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive
Host:  46-71 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HSP105 A24-7
Chemical type: Peptide from protein
Sequence: EYVYEFRDKL
Position: 640-649
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A24-7
Chemical type: Peptide from protein
Sequence: EYVYEFRDKL
Position: 640-649
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive-High
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A24-8
Chemical type: Peptide from protein
Sequence: HYAKIAADF
Position: 725-733
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A24-9
Chemical type: Peptide from protein
Sequence: KYNHIDESEM
Position: 739-748
Source molecule (GenBank): Q92598.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A24-1
Chemical type: Peptide from protein
Sequence: NYGIYKQDL
Position: 180-188
Source molecule (GenBank): Q61699.2
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A24-2
Chemical type: Peptide from protein
Sequence: AFNKGKLKVL
Position: 214-223
Source molecule (GenBank): Q61699.2
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A24-3
Chemical type: Peptide from protein
Sequence: KYKLDAKSKI
Position: 251-260
Source molecule (GenBank): Q61699.2
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A24-4
Chemical type: Peptide from protein
Sequence: QFEELCAEL
Position: 305-313
Source molecule (GenBank): Q61699.2
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A24-5
Chemical type: Peptide from protein
Sequence: TFLRRGPFEL
Position: 433-442
Source molecule (GenBank): Q61699.2
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A24-8
Chemical type: Peptide from protein
Sequence: HYAKIAADF
Position: 726-734
Source molecule (GenBank): Q61699.2
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HSP105 A24-9
Chemical type: Peptide from protein
Sequence: KYNHIDESEM
Position: 740-749
Source molecule (GenBank): Q61699.2
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated