Reference: Parth Narendran; Alistair J Williams; Kathryn Elsegood; Nicola J Leech; Colin M Dayan. "Humoral and cellular immune responses to proinsulin in adults with newly diagnosed type 1 diabetes." Diabetes/metabolism research and reviews (2003).

Epitope: Insulin (1-16)
Chemical type: Peptide from protein
Sequence: FVNQHLCGSHLVEALY
Position: 25-40
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 340 341 316 515 318
Host:  17-36 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Insulin (7-23)
Chemical type: Peptide from protein
Sequence: CGSHLVEALYLVCGERG
Position: 31-47
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 340 341 316 515 318
Host:  17-36 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Insulin (14-30)
Chemical type: Peptide from protein
Sequence: ALYLVCGERGFFYTPKT
Position: 38-54
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 340 341 316 515 318
Host:  17-36 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Insulin (21-37)
Chemical type: Peptide from protein
Sequence: ERGFFYTPKTRREAEDL
Position: 45-61
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 340 341 316 515 318
Host:  17-36 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Insulin (28-44)
Chemical type: Peptide from protein
Sequence: PKTRREAEDLQVGQVEL
Position: 52-68
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 340 341 316 515 318
Host:  17-36 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Insulin (42-58)
Chemical type: Peptide from protein
Sequence: VELGGGPGAGSLQPLAL
Position: 66-82
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 340 341 316 515 318
Host:  17-36 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Insulin (49-65)
Chemical type: Peptide from protein
Sequence: GAGSLQPLALEGSLQKR
Position: 73-89
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 340 341 316 515 318
Host:  17-36 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Insulin (56-72)
Chemical type: Peptide from protein
Sequence: LALEGSLQKRGIVEQCC
Position: 80-96
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 340 341 316 515 318
Host:  17-36 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Insulin (63-79)
Chemical type: Peptide from protein
Sequence: QKRGIVEQCCTSICSLY
Position: 87-103
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 340 341 316 515 318
Host:  17-36 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Insulin (70-86)
Chemical type: Peptide from protein
Sequence: CCTSICSLYQLENYCN
Position: 95-110
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
MHC allele types: 340 341 316 515 318
Host:  17-36 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo