Reference: Christopher O Barnes; Harry B Gristick; Natalia T Freund; Amelia Escolano; Artem Y Lyubimov; Harald Hartweger; Anthony P West; Aina E Cohen; Michel C Nussenzweig; Pamela J Bjorkman. "Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope." Nature communications (2018).

Epitope: Epitope of 35O22 Fab on HIV-1 clade A gp120/gp41
Chemical type: Region on multi-chain protein
Discontinuous residues: B: T526, R614, N615, S617, E618, D621, N622, M623, T624, Q627, K630; G: E86, T89, E90, E91, P237, P239
Source molecule (GenBank): Q2N0S7
Assay category: BCell
Result: Positive
Quantitative measurement: 3.8

Epitope: Epitope of 35O22 Fab on HIV-1 clade A gp120/gp41
Chemical type: Region on multi-chain protein
Discontinuous residues: B: T526, R614, N615, S617, E618, D621, N622, M623, T624, Q627, K630; G: E86, T89, E90, E91, P237, P239
Source molecule (GenBank): Q2N0S7
Assay category: BCell
Result: Positive
Quantitative measurement: 4.1

Epitope: Epitope of BG18 Fab on HIV-1 clade A gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: T134, N136, I137, T138, D323, I324, R325, Q326, A327, H328, T412, L413, P414
Source molecule (GenBank): Q2N0S6.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.8

Epitope: Epitope of BG18 Fab on HIV-1 clade A gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: T134, N136, I137, T138, D323, I324, R325, Q326, A327, H328, T412, L413, P414
Source molecule (GenBank): Q2N0S6.1
Assay category: BCell
Result: Positive
Quantitative measurement: 100000.0

Epitope: Epitope of BG18 Fab on HIV-1 clade A gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: T134, N136, I137, T138, D323, I324, R325, Q326, A327, H328, T412, L413, P414
Source molecule (GenBank): Q2N0S6.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00016

Epitope: Epitope of BG18 Fab on HIV-1 clade A gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: T134, N136, I137, T138, D323, I324, R325, Q326, A327, H328, T412, L413, P414
Source molecule (GenBank): Q2N0S6.1
Assay category: BCell
Result: Positive

Epitope: Epitope of BG18 Fab on HIV-1 clade A gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: T134, N136, I137, T138, D323, I324, R325, Q326, A327, H328, T412, L413, P414
Source molecule (GenBank): Q2N0S6.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.6

Epitope: Epitope of BG18 Fab on HIV-1 clade A gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: T134, N136, I137, T138, D323, I324, R325, Q326, A327, H328, T412, L413, P414
Source molecule (GenBank): Q2N0S6.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.1

Epitope: Epitope of BG18 Fab on HIV-1 clade A gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: T134, N136, I137, T138, D323, I324, R325, Q326, A327, H328, T412, L413, P414
Source molecule (GenBank): Q2N0S6.1
Assay category: BCell
Result: Positive
Quantitative measurement: 6.801

Epitope: Epitope of IOMA Fab on HIV-1 clade A gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: N196, T197, T277, N278, N279, A280, R358, S363, G364, G365, D366, E368, V369, Q425, I427, R453, D454, G455, G456, T464, R466, D471, R473, R477
Source molecule (GenBank): Q2N0S6.1
Assay category: BCell
Result: Positive
Quantitative measurement: 6.801

Epitope: Epitope of 35O22 Fab on HIV-1 clade B gp120/gp41
Chemical type: Region on multi-chain protein
Discontinuous residues: B: T622, N624, E625, D628, N629, M633, Q634; G: N86, T88, P247, C248
Source molecule (GenBank): ACE67267.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.85

Epitope: Epitope of BG18 Fab on HIV-1 clade B gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: T134, N135, T137, N333, R335, H338
Source molecule (GenBank): ACE67267.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.85