Reference: Lei Yan; Fulian Wang; Michelle Hill; Juliane Brun; Ze Liang; Xinyu Shi; Liangminghui Zhang; Xiuxiu He; Yu Li; Qianping Huang; Xuxue Dong; Huanzhen Liu; Yi Zhang; Lili Liu; Raymond A Dwek; Nicole Zitzmann; Aibin Liang; Guang Yang. "A broadly neutralizing antibody recognizes a unique epitope with a signature motif common across coronaviruses." Nature communications (2025).

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.4

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.1

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.4

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.57

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.2

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 7.2

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 5.3

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 11.0

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.36

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 11.0

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 9.0

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 25.0

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.4

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 12.1

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 6.8

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.14

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 19.0

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.16

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 13.0

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 15.0

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.0

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.51

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.03

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.7

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on SARS-CoV-2 S HR1 peptide
Chemical type: Peptide from protein
Sequence: DVVNQN
Position: 950-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.28

Epitope: Epitope of 3D1 on HCoV-229E S peptide
Chemical type: Peptide from protein
Sequence: DVVNQQ
Position: 835-840
Source molecule (GenBank): P15423.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.14

Epitope: Epitope of 3D1 on HCoV-229E S peptide
Chemical type: Peptide from protein
Sequence: DVVNQQ
Position: 835-840
Source molecule (GenBank): P15423.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 3D1 on HCoV-229E S peptide
Chemical type: Peptide from protein
Sequence: DVVNQQ
Position: 835-840
Source molecule (GenBank): P15423.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.28

Epitope: MERS-CoV HR1 peptide
Chemical type: Peptide from protein
Sequence: VGITQQ
Position: 983-988
Source molecule (GenBank): AHX00711.1
Assay category: BCell
Result: Positive

Epitope: MERS-CoV HR1 peptide
Chemical type: Peptide from protein
Sequence: VGITQQ
Position: 983-988
Source molecule (GenBank): AHX00711.1
Assay category: BCell
Result: Positive
Quantitative measurement: 13.0

Epitope: CCoV-HuPn-2018 HR1 peptide
Chemical type: Peptide from protein
Sequence: TVQLQN
Position: 1117-1122
Source molecule (GenBank): QVL91811.1
Assay category: BCell
Result: Positive
Quantitative measurement: 19.0

Epitope: CCoV-HuPn-2018 HR1 peptide
Chemical type: Peptide from protein
Sequence: TVQLQN
Position: 1117-1122
Source molecule (GenBank): QVL91811.1
Assay category: BCell
Result: Positive

Epitope: MARV peptide
Chemical type: Peptide from protein
Sequence: GLYTAVLIKNQNNLV
Position: 542-556
Source molecule (GenBank): P35253.1
Assay category: BCell
Result: Positive
Quantitative measurement: 15.0

Epitope: HIV peptide
Chemical type: Peptide from protein
Sequence: LLSGIVQQQNNLL
Position: 535-547
Source molecule (GenBank): Q6BC19
Assay category: BCell
Result: Positive
Quantitative measurement: 3.0

Epitope: BaEV peptide
Chemical type: Peptide from protein
Sequence: DSLAEVVLQNRRGLD
Position: 433-447
Source molecule (GenBank): P10269.1
Assay category: BCell
Result: Positive
Quantitative measurement: 25.0

Epitope: HCoV-NL63 HR1C peptide
Chemical type: Peptide from protein
Sequence: AIHTVTIALNKIQDVVNQQ
Position: 1002-1020
Source molecule (GenBank): QEG03731.1
Assay category: BCell
Result: Positive

Epitope: HCoV-NL63 HR1C peptide
Chemical type: Peptide from protein
Sequence: AIHTVTIALNKIQDVVNQQ
Position: 1002-1020
Source molecule (GenBank): QEG03731.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.36

Epitope: SADS-CoV HR1C peptide
Chemical type: Peptide from protein
Sequence: LALTTSSALQAIQAVVNQN
Position: 791-809
Source molecule (GenBank): MF094681
Assay category: BCell
Result: Positive
Quantitative measurement: 7.2

Epitope: BANAL-20-247 HR1C peptide
Chemical type: Peptide from protein
Sequence: SLLSTASALGKLQDVVNQN
Position: 891-909
Source molecule (GenBank): UAY13265.1
Assay category: BCell
Result: Positive
Quantitative measurement: 12.1

Epitope: BM48-31 HR1C peptide
Chemical type: Peptide from protein
Sequence: SLSTTTTALGKLQDVINQN
Position: 923-941
Source molecule (GenBank): YP_003858584.1
Assay category: BCell
Result: Positive
Quantitative measurement: 9.0

Epitope: RpYN06 R1C peptide
Chemical type: Peptide from protein
Sequence: SLTSTASALGKLQDVVNQN
Position: 910-928
Source molecule (GenBank): QWN56252.1
Assay category: BCell
Result: Positive
Quantitative measurement: 6.8

Epitope: FCoV HR1C peptide
Chemical type: Peptide from protein
Sequence: GFNTMASALTKIQSVVNQQ
Position: 1112-1130
Source molecule (GenBank): ABI14448.1
Assay category: BCell
Result: Positive
Quantitative measurement: 5.3

Epitope: white-eye HKU16 HR1C peptide
Chemical type: Peptide from protein
Sequence: ALLTVSNAINKIQTVVNQQ
Position: 826-844
Source molecule (GenBank): YP_005352838.1
Assay category: BCell
Result: Positive
Quantitative measurement: 11.0

Epitope: SARS-CoV-2 HR1C
Chemical type: Peptide from protein
Sequence: SLSSTASALGKLQDVVNQN
Position: 937-955
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.2

Epitope: HKU13 HR1C peptide
Chemical type: Peptide from protein
Sequence: ALNTVANAINKIQTVVNQQ
Position: 802-820
Source molecule (GenBank): YP_002308506.1
Assay category: BCell
Result: Positive
Quantitative measurement: 11.0

Epitope: Canada goose CoV HR1C peptide
Chemical type: Peptide from protein
Sequence: GFEATSSALQQIQDVVNQQ
Position: 829-847
Source molecule (GenBank): YP_009755897.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.24