Reference: Saskia C Stein; Guido Hansen; George Ssebyatika; Luisa J Ströh; Okechukwu Ochulor; Elisabeth Herold; Britta Schwarzloh; Doris Mutschall; Jasmin Zischke; Anne K Cordes; Talia Schneider; Imke Hinrichs; Rainer Blasczyk; Hannah Kleine-Weber; Markus Hoffmann; Florian Klein; Franziska K Kaiser; Mariana Gonzalez-Hernandez; Federico Armando; Malgorzata Ciurkiewicz; Georg Beythien; Stefan Pöhlmann; Wolfgang Baumgärtner; Albert Osterhaus; Thomas F Schulz; Thomas Krey. "A human monoclonal antibody neutralizing SARS-CoV-2 Omicron variants containing the L452R mutation." Journal of virology (2024).

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.24

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00019

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 780000.0

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000069

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.083

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 840000.0

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.11

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of pT1616 Fab on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, W353, N354, R355, K356, R357, S359, Y449, N450, L452, R457, K462, P463, F464, E465, R466, D467, I468, S469, T470, I472, G482, V483, E484, F490, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High