Reference: Aaron W Michels; David A Ostrov; Li Zhang; Maki Nakayama; Masanori Fuse; Kristen McDaniel; Bart O Roep; Peter A Gottlieb; Mark A Atkinson; George S Eisenbarth. "Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentation." Journal of immunology (Baltimore, Md. : 1950) (2011).

Epitope: [p1:6]  S-(2-(dimethylamino)ethyl) hydrogen thiosulfate
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive

Epitope: [p1:17]  8-azaguanine
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive

Epitope: [p6:4]  1,3,6,8-tetraazatricyclo(6.2.1.1(3,6))dodecane
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive

Epitope: [p6:4]  1,3,6,8-tetraazatricyclo(6.2.1.1(3,6))dodecane
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive

Epitope: [p6:17]  [1,3]dithiolo[4,5-b]quinoxaline-2,2-diamine
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive

Epitope: [p6:18]  9-thia-1,3,6,8-tetraazatricyclo[4.3.1.1--3,8--] undecane 9,9-dioxide
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive

Epitope: [p9:12]  glyphosine
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Host: F 10 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: [p9:12]  glyphosine
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Host: F 4 weeks

Epitope: [p9:12]  glyphosine
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 70600.0

Epitope: [p9]  glyphosine derivative 2
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 194.0

Epitope: Insulin B:9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Positive
Host: F 10 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Insulin B:9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Positive-Low
Host:  9-39 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Insulin B:9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: Insulin B:9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Positive
Host: F 10 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Insulin B:9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: Insulin B:9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Positive
Host: M 18 years
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: Insulin B:9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Positive-Low
Host:  9-39 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: chromogranin mimotope
Chemical type: Peptide, no natural source
Sequence: EKAHRPIWARMDAKK
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone (Hybridoma)