LiteFold/IEDB huggingface dataset:
Reference: Joseph G Jardine; Devin Sok; Jean-Philippe Julien; Bryan Briney; Anita Sarkar; Chi-Hui Liang; Erin A Scherer; Carole J Henry Dunand; Yumiko Adachi; Devan Diwanji; Jessica Hsueh; Meaghan Jones; Oleksandr Kalyuzhniy; Michael Kubitz; Skye Spencer; Matthias Pauthner; Karen L Saye-Francisco; Fabian Sesterhenn; Patrick C Wilson; Denise M Galloway; Robyn L Stanfield; Ian A Wilson; Dennis R Burton; William R Schief. "Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design." PLoS pathogens (2016).

Epitope: Epitope of VRC01 Fab on HIV-1 gp120 engineered outer domain eOD
Chemical type: Discontinuous protein residues
Discontinuous residues: T455, R456, D457, G458, G459, N460, S465, R469, G472, D474, R476, N276, T278, D279, N280, A281, S365, G366, G367, D368, I371
Source molecule (GenBank): P04578.2
Assay category: BCell
Result: Positive
Quantitative measurement: 3.25

Epitope: Epitope of VRC01 Fab on HIV-1 gp120 engineered outer domain eOD
Chemical type: Discontinuous protein residues
Discontinuous residues: T455, R456, D457, G458, G459, N460, S465, R469, G472, D474, R476, N276, T278, D279, N280, A281, S365, G366, G367, D368, I371
Source molecule (GenBank): P04578.2
Assay category: BCell
Result: Positive

Epitope: Epitope of PGT122 Fab on HIV-1 gp120 BG505 SOSIP
Chemical type: Discontinuous protein residues
Discontinuous residues: K58, T134, N135, N136, I137, T138, D139, D140, M141, Q292, I293, N294, C295, T296, R297, P298, N299, N300, N301, D319, I320, I321, G322, D323, I324, R325, Q326, A327, H328, C329, V331, S332, N408, D409, S410, I411, T412, L413, P414, Q437, G438, V439, I440, R441, C442, V443, S444, N445
Source molecule (GenBank): Q2N0S6.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.4
Reference: P Fredman; L Mattsson; K Andersson; P Davidsson; I Ishizuka; S Jeansson; J E Månsson; L Svennerholm. "Characterization of the binding epitope of a monoclonal antibody to sulphatide." The Biochemical journal (1988).

Epitope: sulphatide (3'-sulphogalactosylceramide)
Chemical type: Glycolipid
Assay category: BCell
Result: Positive-Intermediate

Epitope: sulphatide (3'-sulphogalactosylceramide)
Chemical type: Glycolipid
Assay category: BCell
Result: Positive

Epitope: sulphatide (3'-sulphogalactosylceramide)
Chemical type: Glycolipid
Assay category: BCell
Result: Positive

Epitope: sulphatide (3'-sulphogalactosylceramide)
Chemical type: Glycolipid
Assay category: BCell
Result: Positive

Epitope: sulphatide (3'-sulphogalactosylceramide)
Chemical type: Glycolipid
Assay category: BCell
Result: Positive-Intermediate

Epitope: sulphatide (3'-sulphogalactosylceramide)
Chemical type: Glycolipid
Assay category: BCell
Result: Positive-Intermediate

Epitope: sulphatide (3'-sulphogalactosylceramide)
Chemical type: Glycolipid
Assay category: BCell
Result: Positive

Epitope: Lactosylceramide 3-sulphate
Chemical type: Glycolipid
Assay category: BCell
Result: Positive

Epitope: Lysosulphatide
Chemical type: Glycolipid
Assay category: BCell
Result: Positive-Intermediate

Epitope: Lysosulphatide
Chemical type: Glycolipid
Assay category: BCell
Result: Positive-Intermediate

Epitope: Seminolipid
Chemical type: Glycolipid
Assay category: BCell
Result: Positive

Epitope: Lysoseminolipid
Chemical type: Glycolipid
Assay category: BCell
Result: Positive-Intermediate
Reference: Michelle P Ashton; Anne Eugster; Denise Walther; Natalie Daehling; Stephanie Riethausen; Denise Kuehn; Karin Klingel; Andreas Beyerlein; Stephanie Zillmer; Anette-Gabriele Ziegler; Ezio Bonifacio. "Incomplete immune response to coxsackie B viruses associates with early autoimmunity against insulin." Scientific reports (2016).

Epitope: GAD65 (247-266)
Chemical type: Peptide from protein
Sequence: NMYAMMIARFKMFPEVKEKG
Position: 247-266
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: GAD65 (247-266)
Chemical type: Peptide from protein
Sequence: NMYAMMIARFKMFPEVKEKG
Position: 247-266
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: GAD65 (247-266)
Chemical type: Peptide from protein
Sequence: NMYAMMIARFKMFPEVKEKG
Position: 247-266
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: CVB4 p2C (30-51)
Chemical type: Peptide from protein
Sequence: WLKNKLIPEVKEKHEFLSRL
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: CVB4 p2C (30-51)
Chemical type: Peptide from protein
Sequence: WLKNKLIPEVKEKHEFLSRL
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: CVB4 p2C (30-51)
Chemical type: Peptide from protein
Sequence: WLKNKLIPEVKEKHEFLSRL
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone
Reference: Sonia Hesam Shariati; Anoosha Alaei; Rouhollah Keshavarz; Nader Mosavari; Ali Rabbani; Magdalena Niegowska; Leonardo A Sechi; Mohammad Mehdi Feizabadi. "Detection of Mycobacterium avium subsp. paratuberculosis in Iranian patients with type 1 diabetes mellitus by PCR and ELISA." Journal of infection in developing countries (2016).

Epitope: MAP3865c 125–133
Chemical type: Peptide from protein
Sequence: MIAVALAGL
Position: 125-133
Source molecule (GenBank): NP_962799.1
Assay category: BCell
Result: Positive
Host:  8-30 years

Epitope: MAP3865c 125–133
Chemical type: Peptide from protein
Sequence: MIAVALAGL
Position: 125-133
Source molecule (GenBank): NP_962799.1
Assay category: BCell
Result: Positive-Low
Host:  8-30 years

Epitope: MAP3865c 133-141
Chemical type: Peptide from protein
Sequence: LAANFVVAL
Position: 133-141
Source molecule (GenBank): NP_962799.1
Assay category: BCell
Result: Positive
Host:  8-30 years

Epitope: MAP3865c 133-141
Chemical type: Peptide from protein
Sequence: LAANFVVAL
Position: 133-141
Source molecule (GenBank): NP_962799.1
Assay category: BCell
Result: Positive-Low
Host:  8-30 years

Epitope: MAP ZnT8 178-186
Chemical type: Peptide from protein
Sequence: MIIVSSCAV
Position: 178-186
Source molecule (GenBank): Q8IWU4.2
Assay category: BCell
Result: Negative
Host:  8-30 years

Epitope: MAP ZnT8 178-186
Chemical type: Peptide from protein
Sequence: MIIVSSCAV
Position: 178-186
Source molecule (GenBank): Q8IWU4.2
Assay category: BCell
Result: Positive
Host:  8-30 years

Epitope: MAP ZnT8 186-194
Chemical type: Peptide from protein
Sequence: VAANIVLTV
Position: 186-194
Source molecule (GenBank): Q8IWU4.2
Assay category: BCell
Result: Negative
Host:  8-30 years

Epitope: MAP ZnT8 186-194
Chemical type: Peptide from protein
Sequence: VAANIVLTV
Position: 186-194
Source molecule (GenBank): Q8IWU4.2
Assay category: BCell
Result: Positive
Host:  8-30 years
Reference: Tian-Fei Yu; Bo Ma; Jun-Wei Wang. "Identification of linear B-cell epitopes on goose parvovirus non-structural protein." Veterinary immunology and immunopathology (2016).

Epitope: NS (498-532)
Chemical type: Peptide from protein
Sequence: EPVPERANEPKEPPKIWAPPTREELEELLRASPEL
Position: 498-532
Source molecule (GenBank): AFI49447.1
Assay category: BCell
Result: Positive

Epitope: NS (498-532)
Chemical type: Peptide from protein
Sequence: EPVPERANEPKEPPKIWAPPTREELEELLRASPEL
Position: 498-532
Source molecule (GenBank): AFI49447.1
Assay category: BCell
Result: Positive
Reference: Xiaofei Li; Liting Qin; Haibo Zhu; Yingjun Sun; Xuezhi Cui; Yadong Gao; Xiaole Qi; Yongqiang Wang; Honglei Gao; Yulong Gao; Xiaomei Wang. "Identification of a linear B-cell epitope on the avian leukosis virus P27 protein using monoclonal antibodies." Archives of virology (2016).

Epitope: mAb 3A9 (P27 181-185)
Chemical type: Peptide from protein
Sequence: PPSAR
Position: 423-427
Source molecule (GenBank): ABC94885.1
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: mAb 3A9 (P27 181-185)
Chemical type: Peptide from protein
Sequence: PPSAR
Position: 423-427
Source molecule (GenBank): ABC94885.1
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: mAb 3A9 (P27 181-185)
Chemical type: Peptide from protein
Sequence: PPSAR
Position: 423-427
Source molecule (GenBank): ABC94885.1
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: mAb 3A9 (P27 181-185)
Chemical type: Peptide from protein
Sequence: PPSAR
Position: 423-427
Source molecule (GenBank): ABC94885.1
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: mAb 3A9 (P27 181-185)
Chemical type: Peptide from protein
Sequence: PPSAR
Position: 423-427
Source molecule (GenBank): ABC94885.1
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: mAb 3A9 (P27 181-185)
Chemical type: Peptide from protein
Sequence: PPSAR
Position: 423-427
Source molecule (GenBank): ABC94885.1
Assay category: BCell
Result: Positive

Epitope: mAb 3A9 (P27 181-185)
Chemical type: Peptide from protein
Sequence: PPSAR
Position: 423-427
Source molecule (GenBank): ABC94885.1
Assay category: BCell
Result: Positive
Reference: Jin Xiao; Wangzhen Xiang; Yan Chai; Joel Haywood; Jianxun Qi; Limin Ba; Peng Qi; Ming Wang; Jun Liu; George F Gao. "Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I." Journal of immunology (Baltimore, Md. : 1950) (2016).

Epitope: K9
Chemical type: Peptide from protein
Sequence: KLFSGELTK
Position: 289-297
Source molecule (GenBank): XP_853004.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.9

Epitope: K9
Chemical type: Peptide from protein
Sequence: KLFSGELTK
Position: 289-297
Source molecule (GenBank): XP_853004.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 59.8

Epitope: K11
Chemical type: Peptide from protein
Sequence: RFLDKDGFIDK
Position: 444-454
Source molecule (GenBank): NP_001153156.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.0

Epitope: K11
Chemical type: Peptide from protein
Sequence: RFLDKDGFIDK
Position: 444-454
Source molecule (GenBank): NP_001153156.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 61.6

Epitope: K9-P1A
Chemical type: Peptide, no natural source
Sequence: ALFSGELTK
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 57.4

Epitope: K9-P2A
Chemical type: Peptide, no natural source
Sequence: KAFSGELTK
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 55.2

Epitope: K9-P6A
Chemical type: Peptide, no natural source
Sequence: KLFSGALTK
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 56.3

Epitope: K9-P9A
Chemical type: Peptide, no natural source
Sequence: KLFSGELTA
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 34.5

Epitope: K11-P1A
Chemical type: Peptide, no natural source
Sequence: AFLDKDGFIDK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 61.3

Epitope: K11-P2A
Chemical type: Peptide, no natural source
Sequence: RALDKDGFIDK
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 60.8

Epitope: K11-P8A
Chemical type: Peptide, no natural source
Sequence: RFLDKDGAIDK
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 34.2

Epitope: K11-P11A
Chemical type: Peptide, no natural source
Sequence: RFLDKDGFIDA
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 40.4

Epitope: CDV-P1A
Chemical type: Peptide, no natural source
Sequence: AVFPLSVSLSM
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 47.4

Epitope: CDV-P2A
Chemical type: Peptide, no natural source
Sequence: KAFPLSVSLSM
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 46.4

Epitope: CDV-P8A
Chemical type: Peptide, no natural source
Sequence: KVFPLSVALSM
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 52.4

Epitope: CDV-P11A
Chemical type: Peptide, no natural source
Sequence: KVFPLSVSLSA
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 38.7
Reference: Saleh Umair; Qing Deng; Joanna M Roberts; Richard J Shaw; Ian A Sutherland; Anton Pernthaner. "Identification of Peptide Mimics of a Glycan Epitope on the Surface of Parasitic Nematode Larvae." PloS one (2016).

Epitope: PAB1.C7C-7
Chemical type: Peptide, no natural source
Sequence: CPQHFKTFC
Assay category: BCell
Result: Positive

Epitope: PAB1.C7C-3
Chemical type: Peptide, no natural source
Sequence: CSSSPYAWC
Assay category: BCell
Result: Positive

Epitope: PAB1.C7C-3
Chemical type: Peptide, no natural source
Sequence: CSSSPYAWC
Assay category: BCell
Result: Positive

Epitope: PAB1.C7C-3
Chemical type: Peptide, no natural source
Sequence: CSSSPYAWC
Assay category: BCell
Result: Positive

Epitope: PAB1.C7C-3
Chemical type: Peptide, no natural source
Sequence: CSSSPYAWC
Assay category: BCell
Result: Positive
Host: M 2-3 months

Epitope: PAB1.C7C-15
Chemical type: Peptide, no natural source
Sequence: CITTPGFLC
Assay category: BCell
Result: Positive

Epitope: PAB1.C7C-16
Chemical type: Peptide, no natural source
Sequence: CNTPMQRSC
Assay category: BCell
Result: Positive

Epitope: PAB1.C7C-16
Chemical type: Peptide, no natural source
Sequence: CNTPMQRSC
Assay category: BCell
Result: Positive-Low

Epitope: PAB1.C7C-16
Chemical type: Peptide, no natural source
Sequence: CNTPMQRSC
Assay category: BCell
Result: Positive

Epitope: PAB1.C7C-16
Chemical type: Peptide, no natural source
Sequence: CNTPMQRSC
Assay category: BCell
Result: Positive-Low
Host: M 2-3 months

Epitope: PAB1.C7C-17
Chemical type: Peptide, no natural source
Sequence: CSLRGHDLC
Assay category: BCell
Result: Positive

Epitope: PAB1.C7C-17
Chemical type: Peptide, no natural source
Sequence: CSLRGHDLC
Assay category: BCell
Result: Positive

Epitope: PAB1.C7C-18
Chemical type: Peptide, no natural source
Sequence: CTKHTLSIC
Assay category: BCell
Result: Positive

Epitope: PAB1.C7C-18
Chemical type: Peptide, no natural source
Sequence: CTKHTLSIC
Assay category: BCell
Result: Positive

Epitope: PAB1.C7C-4
Chemical type: Peptide, no natural source
Sequence: CKNPTTGTC
Assay category: BCell
Result: Positive-Low

Epitope: PAB1.C7C-4
Chemical type: Peptide, no natural source
Sequence: CKNPTTGTC
Assay category: BCell
Result: Positive
Host: M 2-3 months

Epitope: PAB1.C7C-4
Chemical type: Peptide, no natural source
Sequence: CKNPTTGTC
Assay category: BCell
Result: Positive

Epitope: PAB1.C7C-4
Chemical type: Peptide, no natural source
Sequence: CKNPTTGTC
Assay category: BCell
Result: Positive-Low

Epitope: PAB1.C7C-36
Chemical type: Peptide, no natural source
Sequence: CGEASSPRC
Assay category: BCell
Result: Positive-Low

Epitope: PAB1.C7C-40
Chemical type: Peptide, no natural source
Sequence: CKSTPTNGC
Assay category: BCell
Result: Positive

Epitope: PAB1.C7C-37
Chemical type: Peptide, no natural source
Sequence: CWSSFRDEC
Assay category: BCell
Result: Positive-Low

Epitope: PAB1.C7C-37
Chemical type: Peptide, no natural source
Sequence: CWSSFRDEC
Assay category: BCell
Result: Positive
Reference: Michal Bassani-Sternberg; David Gfeller. "Unsupervised HLA Peptidome Deconvolution Improves Ligand Prediction Accuracy and Predicts Cooperative Effects in Peptide-HLA Interactions." Journal of immunology (Baltimore, Md. : 1950) (2016).

Epitope: GCC1 (526-534)
Chemical type: Peptide from protein
Sequence: ELKEKYISL
Position: 526-534
Source molecule (GenBank): NP_078799.2
Assay category: MhcBinding
Result: Positive-High

Epitope: GCC 1 (525-534)
Chemical type: Peptide from protein
Sequence: AELKEKYISL
Position: 525-534
Source molecule (GenBank): NP_078799.2
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: GCC1 (526-534) analog 1
Chemical type: Peptide, no natural source
Sequence: ELKEAKYISL
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: GCC1 (526-534) analog 2
Chemical type: Peptide, no natural source
Sequence: ELKEKYIASL
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: ANKLE2 protein (512-520)
Chemical type: Peptide from protein
Sequence: SPRDPVLTL
Position: 512-520
Source molecule (GenBank): AAH43157.2
Assay category: MhcBinding
Result: Positive-High

Epitope: ANKLE2 protein (512-520) analog 1
Chemical type: Peptide, no natural source
Sequence: SPQDPVLTL
Assay category: MhcBinding
Result: Positive

Epitope: ANKLE2 protein (512-520) analog 2
Chemical type: Peptide, no natural source
Sequence: SPADPVLTL
Assay category: MhcBinding
Result: Positive

Epitope: ANKLE2 protein (512-520) analog 3
Chemical type: Peptide, no natural source
Sequence: SPRDPVALTL
Assay category: MhcBinding
Result: Positive

Epitope: ANKLE2 protein (512-520) analog 4
Chemical type: Peptide, no natural source
Sequence: SPQDPVALTL
Assay category: MhcBinding
Result: Positive

Epitope: ANKLE2 protein (512-520) analog 5
Chemical type: Peptide, no natural source
Sequence: SPADPVALTL
Assay category: MhcBinding
Result: Positive

Epitope: ANKLE2 protein (512-520) analog 6
Chemical type: Peptide, no natural source
Sequence: SPRDPAVALTL
Assay category: MhcBinding
Result: Positive

Epitope: ANKLE2 protein (512-520) analog 7
Chemical type: Peptide, no natural source
Sequence: SPQDPAVALTL
Assay category: MhcBinding
Result: Positive

Epitope: ANKLE2 protein (512-520) analog 8
Chemical type: Peptide, no natural source
Sequence: SPADPAVALTL
Assay category: MhcBinding
Result: Positive

Epitope: ANKLE2 protein (512-520) analog 9
Chemical type: Peptide, no natural source
Sequence: SPRDPAVSALTL
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: ANKLE2 protein (512-520) analog 10
Chemical type: Peptide, no natural source
Sequence: SPQDPAVSALTL
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: ANKLE2 protein (512-520) analog 11
Chemical type: Peptide, no natural source
Sequence: SPADPAVSALTL
Assay category: MhcBinding
Result: Positive-Intermediate
Reference: Weifeng Liang; Guohui Zhou; Wenming Liu; Baolin Yang; Chaosi Li; Haiwei Wang; Decheng Yang; Wenge Ma; Li Yu. "Identification of a conserved linear neutralizing epitope recognized by monoclonal antibody 9A9 against serotype A foot-and-mouth disease virus." Archives of virology (2016).

Epitope: FMDV VP1 (143-153)
Chemical type: Peptide from protein
Sequence: RGDLGPLAARL
Position: 667-677
Source molecule (GenBank): AGO58327.1
Assay category: BCell
Result: Positive

Epitope: FMDV VP1 (143-153)
Chemical type: Peptide from protein
Sequence: RGDLGPLAARL
Position: 667-677
Source molecule (GenBank): AGO58327.1
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: FMDV VP1 (143-153)
Chemical type: Peptide from protein
Sequence: RGDLGPLAARL
Position: 667-677
Source molecule (GenBank): AGO58327.1
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: FMDV VP1 (143-153)
Chemical type: Peptide from protein
Sequence: RGDLGPLAARL
Position: 667-677
Source molecule (GenBank): AGO58327.1
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: FMDV VP1 (143-153)
Chemical type: Peptide from protein
Sequence: RGDLGPLAARL
Position: 667-677
Source molecule (GenBank): AGO58327.1
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: FMDV VP1 (143-153)
Chemical type: Peptide from protein
Sequence: RGDLGPLAARL
Position: 667-677
Source molecule (GenBank): AGO58327.1
Assay category: BCell
Result: Positive
Reference: Yaming Shao; Hao Huang; Daoming Qin; Nan-Sheng Li; Akiko Koide; Jonathan P Staley; Shohei Koide; Anthony A Kossiakoff; Joseph A Piccirilli. "Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment." Journal of molecular biology (2016).

Epitope: 12 nt ssRNA (R-12)
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 2.38

Epitope: 12 nt ssRNA (R-12)
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Quantitative measurement: 12.0

Epitope: 12 nt ssRNA (R-12)
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Reference: Shenping Liu; Leslie A Dakin; Li Xing; Jane M Withka; Parag V Sahasrabudhe; Wei Li; Mary Ellen Banker; Paul Balbo; Suman Shanker; Boris A Chrunyk; Zuojun Guo; Jinshan M Chen; Jennifer A Young; Guoyun Bai; Jeremy T Starr; Stephen W Wright; Joerg Bussenius; Sheng Tan; Ariamala Gopalsamy; Bruce A Lefker; Fabien Vincent; Lyn H Jones; Hua Xu; Lise R Hoth; Kieran F Geoghegan; Xiayang Qiu; Mark E Bunnage; Atli Thorarensen. "Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists." Scientific reports (2016).

Epitope: Epitope of CAT-2000 Fab on IL-17A
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K38, R39, S40, S41, D42, Y43, R46; B: L74, Y85, H86, M87, N88, Q93, V124, P126, I127
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.8

Epitope: Epitope of CAT-2000 Fab on IL-17A
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K38, R39, S40, S41, D42, Y43, R46; B: L74, Y85, H86, M87, N88, Q93, V124, P126, I127
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.8

Epitope: Epitope of CAT-2000 Fab on IL-17A
Chemical type: Region on multi-chain protein
Discontinuous residues: A: K38, R39, S40, S41, D42, Y43, R46; B: L74, Y85, H86, M87, N88, Q93, V124, P126, I127
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.15
Reference: Dorothy M Kim; Igor Dikiy; Vikrant Upadhyay; David J Posson; David Eliezer; Crina M Nimigean. "Conformational heterogeneity in closed and open states of the KcsA potassium channel in lipid bicelles." The Journal of general physiology (2016).

Epitope: Epitope of Fab on pH-gated potassium channel KcsA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y45, L49, R52, G53, A54, P55, G56, A57, Q58, I60, T61, Y62, P63, R64
Source molecule (GenBank): P0A334.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.4
Reference: Yu Kitago; Mika K Kaneko; Satoshi Ogasawara; Yukinari Kato; Junichi Takagi. "Structural basis for multi-specific peptide recognition by the anti-IDH1/2 monoclonal antibody, MsMab-1." Biochemical and biophysical research communications (2016).

Epitope: IDH1(Ser)
Chemical type: Peptide, no natural source
Sequence: KPIIIGSHAYGD
Assay category: BCell
Result: Positive
Quantitative measurement: 1.93

Epitope: IDH1(Ser)
Chemical type: Peptide, no natural source
Sequence: KPIIIGSHAYGD
Assay category: BCell
Result: Positive

Epitope: IDH2(Ser)
Chemical type: Peptide, no natural source
Sequence: TKPITIGSHAHGDQYK
Assay category: BCell
Result: Positive
Quantitative measurement: 1.93

Epitope: IDH1(R132G)
Chemical type: Peptide, no natural source
Sequence: GGVKPIIIGGHAYGDQYRA
Assay category: BCell
Result: Positive

Epitope: IDH1
Chemical type: Peptide from protein
Sequence: GWVKPIIIGRHAYGDQYRA
Position: 123-141
Source molecule (GenBank): O75874.2
Assay category: BCell
Result: Negative
Reference: Li Zhang; Jin Wang; Aizhang Xu; Conghao Zhong; Wuguang Lu; Li Deng; Rongxiu Li. "A Rationally Designed TNF-α Epitope-Scaffold Immunogen Induces Sustained Antibody Response and Alleviates Collagen-Induced Arthritis in Mice." PloS one (2016).

Epitope: TNF-α (80-97)
Chemical type: Peptide from protein
Sequence: VSRFAISYQEKVNLLSAV
Position: 158-175
Source molecule (GenBank): NP_038721.1
Assay category: BCell
Result: Positive
Host: F 6-7 weeks

Epitope: TNF-α (80-97)
Chemical type: Peptide from protein
Sequence: VSRFAISYQEKVNLLSAV
Position: 158-175
Source molecule (GenBank): NP_038721.1
Assay category: BCell
Result: Positive
Host: M 6 weeks