Reference: Jose L Garrido; Matías A Medina; Felipe Bravo; Sarah McGee; Francisco Fuentes-Villalobos; Mario Calvo; Yazmin Pinos; James W Bowman; Christopher D Bahl; Maria Ines Barria; Rebecca A Brachman; Raymond A Alvarez. "IgG targeting distinct seasonal coronavirus- conserved SARS-CoV-2 spike subdomains correlates with differential COVID-19 disease outcomes." Cell reports (2022).

Epitope: C-terminus domain (CTD1) S1-556-576
Chemical type: Peptide from protein
Sequence: NKKFLPFQQFGRDIADTTDAV
Position: 556-576
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Host:  mean: 38 years

Epitope: C-terminus domain (CTD1) S1-556-576
Chemical type: Peptide from protein
Sequence: NKKFLPFQQFGRDIADTTDAV
Position: 556-576
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low
Host:  mean: 38 years

Epitope: C-terminus domain (CTD2) S1-618-638
Chemical type: Peptide from protein
Sequence: TEVPVAIHADQLTPTWRVYST
Position: 618-638
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Host:  mean: 38 years

Epitope: C-terminus domain (CTD2) S1-618-638
Chemical type: Peptide from protein
Sequence: TEVPVAIHADQLTPTWRVYST
Position: 618-638
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low
Host:  mean: 38 years

Epitope: Furin cleavage site (S1/S2) S1/S2-672- 687
Chemical type: Peptide from protein
Sequence: ASYQTQTNSPRRARSV
Position: 672-687
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Host:  mean: 38 years

Epitope: Furin cleavage site (S1/S2) S1/S2-672- 687
Chemical type: Peptide from protein
Sequence: ASYQTQTNSPRRARSV
Position: 672-687
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low
Host:  mean: 38 years

Epitope: S2' Fusion protein (S2'FP) S2-805-823
Chemical type: Peptide from protein
Sequence: ILPDPSKPSKRSFIEDLLF
Position: 805-823
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Host:  mean: 38 years

Epitope: S2' Fusion protein (S2'FP) S2-805-823
Chemical type: Peptide from protein
Sequence: ILPDPSKPSKRSFIEDLLF
Position: 805-823
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low
Host:  mean: 38 years

Epitope: 5' HR2 flanking region (5'fHR2) S2-1143-1167
Chemical type: Peptide from protein
Sequence: PELDSFKEELDKYFKNHTSPDVDLG
Position: 1143-1167
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Host:  mean: 38 years

Epitope: 5' HR2 flanking region (5'fHR2) S2-1143-1167
Chemical type: Peptide from protein
Sequence: PELDSFKEELDKYFKNHTSPDVDLG
Position: 1143-1167
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low
Host:  mean: 38 years

Epitope: Heptad Repeat- 2 (HR2) region S2-1179-1213
Chemical type: Peptide from protein
Sequence: IQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWP
Position: 1179-1213
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Host:  mean: 38 years

Epitope: Heptad Repeat- 2 (HR2) region S2-1179-1213
Chemical type: Peptide from protein
Sequence: IQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWP
Position: 1179-1213
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low
Host:  mean: 38 years