Reference: M P Protti; A A Manfredi; C Straub; J F Howard; B M Conti-Tronconi. "CD4+ T cell response to the human acetylcholine receptor alpha subunit in myasthenia gravis. A study with synthetic peptides." Journal of immunology (Baltimore, Md. : 1950) (1990).

Epitope: Human AChR alpha residues 1-14
Chemical type: Peptide from protein
Sequence: SEHETRLVAKLFKD
Position: 21-34
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 1-14
Chemical type: Peptide from protein
Sequence: SEHETRLVAKLFKD
Position: 21-34
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 19-34
Chemical type: Peptide from protein
Sequence: VRPVEDHRQVVEVTVG
Position: 39-54
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 19-34
Chemical type: Peptide from protein
Sequence: VRPVEDHRQVVEVTVG
Position: 39-54
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 32-51
Chemical type: Peptide from protein
Sequence: TVGLQLIQLINVDEVNQIVT
Position: 52-71
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 32-51
Chemical type: Peptide from protein
Sequence: TVGLQLIQLINVDEVNQIVT
Position: 52-71
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 48-67
Chemical type: Peptide from protein
Sequence: QIVTTNVRLKQQWVDYNLKW
Position: 68-87
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 48-67
Chemical type: Peptide from protein
Sequence: QIVTTNVRLKQQWVDYNLKW
Position: 68-87
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 63-80
Chemical type: Peptide from protein
Sequence: YNLKWNPDDYGGVKKIHI
Position: 83-100
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 63-80
Chemical type: Peptide from protein
Sequence: YNLKWNPDDYGGVKKIHI
Position: 83-100
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 76-93
Chemical type: Peptide from protein
Sequence: KKIHIPSE
Position: 96-103
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 76-93
Chemical type: Peptide from protein
Sequence: KKIHIPSE
Position: 96-103
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 89-105
Chemical type: Peptide from protein
Sequence: DLVLYNNADGDFAIVKF
Position: 109-125
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 89-105
Chemical type: Peptide from protein
Sequence: DLVLYNNADGDFAIVKF
Position: 109-125
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 118-137
Chemical type: Peptide from protein
Sequence: WTPPAIFKSYCEIIVTHFPF
Position: 138-157
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 118-137
Chemical type: Peptide from protein
Sequence: WTPPAIFKSYCEIIVTHFPF
Position: 138-157
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 135-154
Chemical type: Peptide from protein
Sequence: FPFDEQNCSMKLGTWTYDGS
Position: 155-174
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 135-154
Chemical type: Peptide from protein
Sequence: FPFDEQNCSMKLGTWTYDGS
Position: 155-174
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 151-168
Chemical type: Peptide from protein
Sequence: YDGSVVAINPESDQPDLS
Position: 171-188
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 151-168
Chemical type: Peptide from protein
Sequence: YDGSVVAINPESDQPDLS
Position: 171-188
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 166-185
Chemical type: Peptide from protein
Sequence: SNFMESGEWVIKESRGWK
Position: 188-205
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 166-185
Chemical type: Peptide from protein
Sequence: SNFMESGEWVIKESRGWK
Position: 188-205
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 181-195
Chemical type: Peptide from protein
Sequence: SRGWKHSVTYSCCPD
Position: 201-215
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 181-195
Chemical type: Peptide from protein
Sequence: SRGWKHSVTYSCCPD
Position: 201-215
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 191-207
Chemical type: Peptide from protein
Sequence: SCCPDTPYLDITYHFVM
Position: 211-227
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 191-207
Chemical type: Peptide from protein
Sequence: SCCPDTPYLDITYHFVM
Position: 211-227
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 203-218
Chemical type: Peptide from protein
Sequence: YHFVMQRLPLYFIVNV
Position: 223-238
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 203-218
Chemical type: Peptide from protein
Sequence: YHFVMQRLPLYFIVNV
Position: 223-238
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 214-234
Chemical type: Peptide from protein
Sequence: FIVNVIIPCLLFSFLTGLVFY
Position: 234-254
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 214-234
Chemical type: Peptide from protein
Sequence: FIVNVIIPCLLFSFLTGLVFY
Position: 234-254
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 230-249
Chemical type: Peptide from protein
Sequence: GLVFYLPTDSGEKMTLSISV
Position: 250-269
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 230-249
Chemical type: Peptide from protein
Sequence: GLVFYLPTDSGEKMTLSISV
Position: 250-269
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 246-264
Chemical type: Peptide from protein
Sequence: SISVLLSLTVFLLVIVELI
Position: 266-284
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 246-264
Chemical type: Peptide from protein
Sequence: SISVLLSLTVFLLVIVELI
Position: 266-284
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 261-289
Chemical type: Peptide from protein
Sequence: VELIPSTSSAVPLIGKYMLFTMVFVIASI
Position: 281-309
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 261-289
Chemical type: Peptide from protein
Sequence: VELIPSTSSAVPLIGKYMLFTMVFVIASI
Position: 281-309
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 280-297
Chemical type: Peptide from protein
Sequence: FTMVFVIASIIITVIVIN
Position: 300-317
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 280-297
Chemical type: Peptide from protein
Sequence: FTMVFVIASIIITVIVIN
Position: 300-317
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 304-322
Chemical type: Peptide from protein
Sequence: STHVMPNWVRKVFIDTIPN
Position: 324-342
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 304-322
Chemical type: Peptide from protein
Sequence: STHVMPNWVRKVFIDTIPN
Position: 324-342
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 320-337
Chemical type: Peptide from protein
Sequence: IPNIMFFSTMKRPSREKQ
Position: 340-357
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 320-337
Chemical type: Peptide from protein
Sequence: IPNIMFFSTMKRPSREKQ
Position: 340-357
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 329-347
Chemical type: Peptide from protein
Sequence: MKRPSREKQDKKIFTEDID
Position: 349-367
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 329-347
Chemical type: Peptide from protein
Sequence: MKRPSREKQDKKIFTEDID
Position: 349-367
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 343-356
Chemical type: Peptide from protein
Sequence: TEDIDISDISGKPG
Position: 363-376
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 343-356
Chemical type: Peptide from protein
Sequence: TEDIDISDISGKPG
Position: 363-376
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 352-368
Chemical type: Peptide from protein
Sequence: SGKPGPPPMGFHSPLIK
Position: 372-388
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 352-368
Chemical type: Peptide from protein
Sequence: SGKPGPPPMGFHSPLIK
Position: 372-388
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 364-380
Chemical type: Peptide from protein
Sequence: SPLIKHFEVKSAIEGIK
Position: 384-400
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 364-380
Chemical type: Peptide from protein
Sequence: SPLIKHFEVKSAIEGIK
Position: 384-400
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 376-393
Chemical type: Peptide from protein
Sequence: IEGIKYIAETMKSDQESN
Position: 396-413
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 376-393
Chemical type: Peptide from protein
Sequence: IEGIKYIAETMKSDQESN
Position: 396-413
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 387-400
Chemical type: Peptide from protein
Sequence: KSDQESNNAAAEWK
Position: 407-420
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 387-400
Chemical type: Peptide from protein
Sequence: KSDQESNNAAAEWK
Position: 407-420
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 387-505
Chemical type: Peptide from protein
Sequence: KSDQESNNAAAEWKYVAMV
Position: 407-425
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 387-505
Chemical type: Peptide from protein
Sequence: KSDQESNNAAAEWKYVAMV
Position: 407-425
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 403-421
Chemical type: Peptide from protein
Sequence: AMVMDHILLGVFMLVCIIG
Position: 423-441
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 403-421
Chemical type: Peptide from protein
Sequence: AMVMDHILLGVFMLVCIIG
Position: 423-441
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 419-437
Chemical type: Peptide from protein
Sequence: IIGTLAVFAGRLIELNQQG
Position: 439-457
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 419-437
Chemical type: Peptide from protein
Sequence: IIGTLAVFAGRLIELNQQG
Position: 439-457
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo