Reference: Anne S De Groot; Amy S Rosenberg; S M Shahjahan Miah; Gail Skowron; Brian J Roberts; Sandra Lélias; Frances E Terry; William D Martin. "Identification of a potent regulatory T cell epitope in factor V that modulates CD4+ and CD8+ memory T cell responses." Clinical immunology (Orlando, Fla.) (2021).

Epitope: FV432
Chemical type: Peptide from protein
Sequence: KIVFKNMASRPYSIY
Position: 432-446
Source molecule (GenBank): P12259.4
Assay category: TCell
Result: Negative
Host:  29-76 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: FV432
Chemical type: Peptide from protein
Sequence: KIVFKNMASRPYSIY
Position: 432-446
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2690.0

Epitope: FV432
Chemical type: Peptide from protein
Sequence: KIVFKNMASRPYSIY
Position: 432-446
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2170.0

Epitope: FV432
Chemical type: Peptide from protein
Sequence: KIVFKNMASRPYSIY
Position: 432-446
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 78590.0

Epitope: FV432
Chemical type: Peptide from protein
Sequence: KIVFKNMASRPYSIY
Position: 432-446
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 20110.0

Epitope: FV432
Chemical type: Peptide from protein
Sequence: KIVFKNMASRPYSIY
Position: 432-446
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 7030.0

Epitope: FV432
Chemical type: Peptide from protein
Sequence: KIVFKNMASRPYSIY
Position: 432-446
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 4360.0

Epitope: FV432
Chemical type: Peptide from protein
Sequence: KIVFKNMASRPYSIY
Position: 432-446
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2960.0

Epitope: FV548
Chemical type: Peptide from protein
Sequence: FAVFDENKSWYLEDN
Position: 548-562
Source molecule (GenBank): P12259.4
Assay category: TCell
Result: Negative
Host:  29-76 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: FV548
Chemical type: Peptide from protein
Sequence: FAVFDENKSWYLEDN
Position: 548-562
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 21020.0

Epitope: FV548
Chemical type: Peptide from protein
Sequence: FAVFDENKSWYLEDN
Position: 548-562
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 27510.0

Epitope: FV548
Chemical type: Peptide from protein
Sequence: FAVFDENKSWYLEDN
Position: 548-562
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: FV548
Chemical type: Peptide from protein
Sequence: FAVFDENKSWYLEDN
Position: 548-562
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1620.0

Epitope: FV548
Chemical type: Peptide from protein
Sequence: FAVFDENKSWYLEDN
Position: 548-562
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: FV548
Chemical type: Peptide from protein
Sequence: FAVFDENKSWYLEDN
Position: 548-562
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: FV548
Chemical type: Peptide from protein
Sequence: FAVFDENKSWYLEDN
Position: 548-562
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 29800.0

Epitope: FV582
Chemical type: Peptide from protein
Sequence: ESNIMSTINGYVPES
Position: 582-596
Source molecule (GenBank): P12259.4
Assay category: TCell
Result: Negative
Host:  29-76 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: FV582
Chemical type: Peptide from protein
Sequence: ESNIMSTINGYVPES
Position: 582-596
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: FV582
Chemical type: Peptide from protein
Sequence: ESNIMSTINGYVPES
Position: 582-596
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 80510.0

Epitope: FV582
Chemical type: Peptide from protein
Sequence: ESNIMSTINGYVPES
Position: 582-596
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 96420.0

Epitope: FV582
Chemical type: Peptide from protein
Sequence: ESNIMSTINGYVPES
Position: 582-596
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2790.0

Epitope: FV582
Chemical type: Peptide from protein
Sequence: ESNIMSTINGYVPES
Position: 582-596
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: FV582
Chemical type: Peptide from protein
Sequence: ESNIMSTINGYVPES
Position: 582-596
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: FV582
Chemical type: Peptide from protein
Sequence: ESNIMSTINGYVPES
Position: 582-596
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 4220.0

Epitope: FV1737
Chemical type: Peptide from protein
Sequence: EKDIHSGLIGPLLI
Position: 1737-1750
Source molecule (GenBank): P12259.4
Assay category: TCell
Result: Negative
Host:  29-76 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: FV1737
Chemical type: Peptide from protein
Sequence: EKDIHSGLIGPLLI
Position: 1737-1750
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1920.0

Epitope: FV1737
Chemical type: Peptide from protein
Sequence: EKDIHSGLIGPLLI
Position: 1737-1750
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: FV1737
Chemical type: Peptide from protein
Sequence: EKDIHSGLIGPLLI
Position: 1737-1750
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: FV1737
Chemical type: Peptide from protein
Sequence: EKDIHSGLIGPLLI
Position: 1737-1750
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: FV1737
Chemical type: Peptide from protein
Sequence: EKDIHSGLIGPLLI
Position: 1737-1750
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: FV1737
Chemical type: Peptide from protein
Sequence: EKDIHSGLIGPLLI
Position: 1737-1750
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: FV1737
Chemical type: Peptide from protein
Sequence: EKDIHSGLIGPLLI
Position: 1737-1750
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2020.0

Epitope: FV1802
Chemical type: Peptide from protein
Sequence: SHEFHAINGMIYSLP
Position: 1802-1816
Source molecule (GenBank): P12259.4
Assay category: TCell
Result: Negative
Host:  29-76 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: FV1802
Chemical type: Peptide from protein
Sequence: SHEFHAINGMIYSLP
Position: 1802-1816
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: FV1802
Chemical type: Peptide from protein
Sequence: SHEFHAINGMIYSLP
Position: 1802-1816
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 3370.0

Epitope: FV1802
Chemical type: Peptide from protein
Sequence: SHEFHAINGMIYSLP
Position: 1802-1816
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 84430.0

Epitope: FV1802
Chemical type: Peptide from protein
Sequence: SHEFHAINGMIYSLP
Position: 1802-1816
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: FV1802
Chemical type: Peptide from protein
Sequence: SHEFHAINGMIYSLP
Position: 1802-1816
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: FV1802
Chemical type: Peptide from protein
Sequence: SHEFHAINGMIYSLP
Position: 1802-1816
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: FV1802
Chemical type: Peptide from protein
Sequence: SHEFHAINGMIYSLP
Position: 1802-1816
Source molecule (GenBank): P12259.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 30620.0

Epitope: Tregitope 167
Chemical type: Peptide from protein
Sequence: PAVLQSSGLYSLSSVVTVPSSSLGTQ
Position: 54-79
Source molecule (GenBank): P01857.1
Assay category: TCell
Result: Positive
Host:  29-76 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Tregitope 167
Chemical type: Peptide from protein
Sequence: PAVLQSSGLYSLSSVVTVPSSSLGTQ
Position: 54-79
Source molecule (GenBank): P01857.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: Tregitope 167
Chemical type: Peptide from protein
Sequence: PAVLQSSGLYSLSSVVTVPSSSLGTQ
Position: 54-79
Source molecule (GenBank): P01857.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 11530.0

Epitope: Tregitope 167
Chemical type: Peptide from protein
Sequence: PAVLQSSGLYSLSSVVTVPSSSLGTQ
Position: 54-79
Source molecule (GenBank): P01857.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 12320.0

Epitope: Tregitope 167
Chemical type: Peptide from protein
Sequence: PAVLQSSGLYSLSSVVTVPSSSLGTQ
Position: 54-79
Source molecule (GenBank): P01857.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 12310.0

Epitope: Tregitope 167
Chemical type: Peptide from protein
Sequence: PAVLQSSGLYSLSSVVTVPSSSLGTQ
Position: 54-79
Source molecule (GenBank): P01857.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 66570.0

Epitope: Tregitope 167
Chemical type: Peptide from protein
Sequence: PAVLQSSGLYSLSSVVTVPSSSLGTQ
Position: 54-79
Source molecule (GenBank): P01857.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 81150.0

Epitope: Tregitope 167
Chemical type: Peptide from protein
Sequence: PAVLQSSGLYSLSSVVTVPSSSLGTQ
Position: 54-79
Source molecule (GenBank): P01857.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 7580.0

Epitope: Tregitope 289
Chemical type: Peptide from protein
Sequence: EEQYNSTYRVVSVLTVLHQDW
Position: 176-196
Source molecule (GenBank): P01857.1
Assay category: TCell
Result: Positive
Host:  29-76 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Tregitope 289
Chemical type: Peptide from protein
Sequence: EEQYNSTYRVVSVLTVLHQDW
Position: 176-196
Source molecule (GenBank): P01857.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: Tregitope 289
Chemical type: Peptide from protein
Sequence: EEQYNSTYRVVSVLTVLHQDW
Position: 176-196
Source molecule (GenBank): P01857.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1570.0

Epitope: Tregitope 289
Chemical type: Peptide from protein
Sequence: EEQYNSTYRVVSVLTVLHQDW
Position: 176-196
Source molecule (GenBank): P01857.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1210.0

Epitope: Tregitope 289
Chemical type: Peptide from protein
Sequence: EEQYNSTYRVVSVLTVLHQDW
Position: 176-196
Source molecule (GenBank): P01857.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: Tregitope 289
Chemical type: Peptide from protein
Sequence: EEQYNSTYRVVSVLTVLHQDW
Position: 176-196
Source molecule (GenBank): P01857.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: Tregitope 289
Chemical type: Peptide from protein
Sequence: EEQYNSTYRVVSVLTVLHQDW
Position: 176-196
Source molecule (GenBank): P01857.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1860.0

Epitope: Tregitope 289
Chemical type: Peptide from protein
Sequence: EEQYNSTYRVVSVLTVLHQDW
Position: 176-196
Source molecule (GenBank): P01857.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2110.0

Epitope: FV621_I624A
Chemical type: Peptide, no natural source
Sequence: ILTAHFTGHSFIYGK
Assay category: TCell
Result: Positive
Host:  29-76 years
Cell type: T cell

Epitope: FV621_I624A
Chemical type: Peptide, no natural source
Sequence: ILTAHFTGHSFIYGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1710.0

Epitope: FV621_I624A
Chemical type: Peptide, no natural source
Sequence: ILTAHFTGHSFIYGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10900.0

Epitope: FV621_I624A
Chemical type: Peptide, no natural source
Sequence: ILTAHFTGHSFIYGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 18900.0

Epitope: FV621_I624A
Chemical type: Peptide, no natural source
Sequence: ILTAHFTGHSFIYGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: FV621_I624A
Chemical type: Peptide, no natural source
Sequence: ILTAHFTGHSFIYGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2520.0

Epitope: FV621_I624A
Chemical type: Peptide, no natural source
Sequence: ILTAHFTGHSFIYGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2260.0

Epitope: FV621_G628
Chemical type: Peptide, no natural source
Sequence: ILTIHFTHHSFIYGK
Assay category: TCell
Result: Negative
Host:  29-76 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: FV621_G628
Chemical type: Peptide, no natural source
Sequence: ILTIHFTHHSFIYGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: FV621_G628
Chemical type: Peptide, no natural source
Sequence: ILTIHFTHHSFIYGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: FV621_G628
Chemical type: Peptide, no natural source
Sequence: ILTIHFTHHSFIYGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1040.0

Epitope: FV621_G628
Chemical type: Peptide, no natural source
Sequence: ILTIHFTHHSFIYGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: FV621_G628
Chemical type: Peptide, no natural source
Sequence: ILTIHFTHHSFIYGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0

Epitope: FV621_G628
Chemical type: Peptide, no natural source
Sequence: ILTIHFTHHSFIYGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1000.0