Reference: M-W Lai; K-H Liang; C-T Yeh. "Diverse immune responses to HBV surface epitope variants after vaccine booster in adolescents immunized in infancy." Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases (2019).

Epitope: S16-33 WT
Chemical type: Peptide from protein
Sequence: QAGFFLLTRILTIPQSLD
Position: 16-33
Source molecule (GenBank): ABE01765.1
Assay category: TCell
Result: Positive
Host:  15-21 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S16-33 WT
Chemical type: Peptide from protein
Sequence: QAGFFLLTRILTIPQSLD
Position: 16-33
Source molecule (GenBank): ABE01765.1
Assay category: TCell
Result: Positive
Host:  15-21 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S16-33 L21W
Chemical type: Peptide from protein
Sequence: QAGFFWLTRILTIPQSLD
Position: 16-33
Source molecule (GenBank): CAA53363.1
Assay category: TCell
Result: Positive
Host:  15-21 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S16-33 L21W
Chemical type: Peptide from protein
Sequence: QAGFFWLTRILTIPQSLD
Position: 16-33
Source molecule (GenBank): CAA53363.1
Assay category: TCell
Result: Positive
Host:  15-21 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S16-33 L21S/R24K
Chemical type: Peptide from protein
Sequence: QAGFFSLTKILTIPQSLD
Position: 16-33
Source molecule (GenBank): BAC55954.1
Assay category: TCell
Result: Positive
Host:  15-21 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S16-33 L21S/R24K
Chemical type: Peptide from protein
Sequence: QAGFFSLTKILTIPQSLD
Position: 16-33
Source molecule (GenBank): BAC55954.1
Assay category: TCell
Result: Positive-Low
Host:  15-21 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S16-33 L21S/R24K/Q30L
Chemical type: Peptide from protein
Sequence: QAGFFSLTKILTIPLSLD
Position: 179-196
Source molecule (GenBank): P17397.3
Assay category: TCell
Result: Positive
Host:  15-21 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S16-33 L21S/R24K/Q30L
Chemical type: Peptide from protein
Sequence: QAGFFSLTKILTIPLSLD
Position: 179-196
Source molecule (GenBank): P17397.3
Assay category: TCell
Result: Positive
Host:  15-21 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S213-226 WT
Chemical type: Peptide from protein
Sequence: LPLLPIFFCLWVYI
Position: 213-226
Source molecule (GenBank): AAC06360.1
Assay category: TCell
Result: Positive
Host:  15-21 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S213-226 WT
Chemical type: Peptide from protein
Sequence: LPLLPIFFCLWVYI
Position: 213-226
Source molecule (GenBank): AAC06360.1
Assay category: TCell
Result: Positive
Host:  15-21 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S213-226 F219Y
Chemical type: Peptide from protein
Sequence: LPLLPIYFCLWVYI
Position: 213-226
Source molecule (GenBank): ATV92755.1
Assay category: TCell
Result: Positive
Host:  15-21 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S213-226 F219Y
Chemical type: Peptide from protein
Sequence: LPLLPIYFCLWVYI
Position: 213-226
Source molecule (GenBank): ATV92755.1
Assay category: TCell
Result: Positive
Host:  15-21 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S213-226 L213I/F220C
Chemical type: Peptide from protein
Sequence: IPLLPIFCCLWVSI
Position: 213-226
Source molecule (GenBank): CAA53348.1
Assay category: TCell
Result: Positive
Host:  15-21 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S213-226 L213I/F220C
Chemical type: Peptide from protein
Sequence: IPLLPIFCCLWVSI
Position: 213-226
Source molecule (GenBank): CAA53348.1
Assay category: TCell
Result: Positive
Host:  15-21 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S213-226 V223A/S224Y
Chemical type: Peptide from protein
Sequence: LPLLPIFCCLWAYI
Position: 213-226
Source molecule (GenBank): ABE01571.1
Assay category: TCell
Result: Positive
Host:  15-21 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S213-226 V223A/S224Y
Chemical type: Peptide from protein
Sequence: LPLLPIFCCLWAYI
Position: 213-226
Source molecule (GenBank): ABE01571.1
Assay category: TCell
Result: Positive
Host:  15-21 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S119-145 P120A
Chemical type: Peptide from protein
Sequence: GACKTCTTPAQGNSMFPSCCCTKPTDG
Position: 6-32
Source molecule (GenBank): AAO40347.1
Assay category: BCell
Result: Positive-Low
Host:  15-21 years

Epitope: S124-147 G145R
Chemical type: Peptide from protein
Sequence: CTTPAQGNSMFPSCCCTKPTDRNC
Position: 124-147
Source molecule (GenBank): AAD31851.1
Assay category: BCell
Result: Positive-Low
Host:  15-21 years

Epitope: S124-147 F161L (rtI169T)
Chemical type: Peptide from protein
Sequence: CIPIPSSWAFAKLLWEWASVRFSWLS
Position: 149-174
Source molecule (GenBank): AGN92518.1
Assay category: BCell
Result: Positive
Host:  15-21 years

Epitope: S149-174 E164D (rtV173L)
Chemical type: Peptide from protein
Sequence: CIPIPSSWAFAKLLWEWASVRFSWLS
Position: 149-174
Source molecule (GenBank): AGN92518.1
Assay category: BCell
Result: Positive
Host:  15-21 years

Epitope: S149-177 L175F/L176V (rtT184C,F,G,L,S)
Chemical type: Peptide, no natural source
Sequence: CIPIPSSWAFAKYLWDWASVRFSWLSFVV
Assay category: BCell
Result: Positive
Host:  15-21 years

Epitope: S149-172 W172*(rtA181T)
Chemical type: Peptide from protein
Sequence: CIPIPSSWAFAKYLWEWASVRFS
Position: 149-171
Source molecule (GenBank): ABE01765.1
Assay category: BCell
Result: Positive
Host:  15-21 years

Epitope: S193-202 I195M (rtM204V)
Chemical type: Peptide from protein
Sequence: SVMWMMWYWG
Position: 412-421
Source molecule (GenBank): ADD17630.1
Assay category: BCell
Result: Positive
Host:  15-21 years

Epitope: S193-202 W196S (rtM204I)
Chemical type: Peptide from protein
Sequence: SVISMMWYWG
Position: 372-381
Source molecule (GenBank): BAG70811.1
Assay category: BCell
Result: Positive
Host:  15-21 years

Epitope: S124-147 T126A
Chemical type: Peptide from protein
Sequence: CTTPAQGNSMFPSCCCTKPTDGNC
Position: 85-108
Source molecule (GenBank): Q0EED2.1
Assay category: BCell
Result: Positive
Host:  15-21 years