Reference: Anna H Mooney; Sarah L Draper; Olivia K Burn; Regan J Anderson; Benjamin J Compton; Chingwen Tang; Kathryn J Farrand; Pietro Di Lucia; Micol Ravà; Valeria Fumagalli; Leonardo Giustini; Elisa Bono; Dale I Godfrey; William R Heath; Weiming Yuan; Francis V Chisari; Luca G Guidotti; Matteo Iannacone; John Sidney; Alessandro Sette; Shivali A Gulab; Gavin F Painter; Ian F Hermans. "Preclinical evaluation of therapeutic vaccines for chronic hepatitis B that stimulate antiviral activities of T cells and NKT cells." JHEP reports : innovation in hepatology (2024).

Epitope: HBsAg 179-186
Chemical type: Peptide from protein
Sequence: FVQWFVGL
Position: 179-186
Source molecule (GenBank): ABE01571.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBsAg 353-360
Chemical type: Peptide from protein
Sequence: VWLSVIWM
Position: 364-371
Source molecule (GenBank): Q2EID8.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBsAg 371-378
Chemical type: Peptide from protein
Sequence: ILSPFLPL
Position: 371-378
Source molecule (GenBank): V5JZH5.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBsAg 93-100
Chemical type: Peptide from protein
Sequence: MGLKFRQL
Position: 93-100
Source molecule (GenBank): AAL31859.1
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBsAg 93-100
Chemical type: Peptide from protein
Sequence: MGLKFRQL
Position: 93-100
Source molecule (GenBank): AAL31859.1
Assay category: TCell
Result: Negative

Epitope: HBsAg 93-100
Chemical type: Peptide from protein
Sequence: MGLKFRQL
Position: 93-100
Source molecule (GenBank): AAL31859.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBsAg 93-100
Chemical type: Peptide from protein
Sequence: MGLKFRQL
Position: 93-100
Source molecule (GenBank): AAL31859.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Culture conditions: Direct Ex Vivo

Epitope: HBsAg 93-100
Chemical type: Peptide from protein
Sequence: MGLKFRQL
Position: 93-100
Source molecule (GenBank): AAL31859.1
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBsAg 93-100
Chemical type: Peptide from protein
Sequence: MGLKFRQL
Position: 93-100
Source molecule (GenBank): AAL31859.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBsAg 93-100
Chemical type: Peptide from protein
Sequence: MGLKFRQL
Position: 93-100
Source molecule (GenBank): AAL31859.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBsAg 93-100
Chemical type: Peptide from protein
Sequence: MGLKFRQL
Position: 93-100
Source molecule (GenBank): AAL31859.1
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBsAg 93-100
Chemical type: Peptide from protein
Sequence: MGLKFRQL
Position: 93-100
Source molecule (GenBank): AAL31859.1
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBsAg 47-56
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 47-56
Source molecule (GenBank): A0A0H4BJV6.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBsAg 136-144
Chemical type: Peptide from protein
Sequence: CLTFGRETV
Position: 71-79
Source molecule (GenBank): AAQ67370.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBsAg 72-82
Chemical type: Peptide from protein
Sequence: LTFGRETVLEN
Position: 72-82
Source molecule (GenBank): Q6UFV9.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: HBsAg 652-660
Chemical type: Peptide from protein
Sequence: FLKQQYMNL
Position: 652-660
Source molecule (GenBank): AFH87851.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo