Reference: Hiromitsu Asashima; Hiroto Tsuboi; Hiroyuki Takahashi; Tomoya Hirota; Mana Iizuka; Yuya Kondo; Minoru Matsui; Isao Matsumoto; Takayuki Sumida. "The anergy induction of M3 muscarinic acetylcholine receptor-reactive CD4+ T cells suppresses experimental sialadenitis-like Sjögren's syndrome." Arthritis & rheumatology (Hoboken, N.J.) (2015).

Epitope: M3R N1 peptide
Chemical type: Peptide from protein
Sequence: MTLHSNSTTSPLFPNISSSWVHSPSEAGLP
Position: 1-30
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R N1 peptide
Chemical type: Peptide from protein
Sequence: MTLHSNSTTSPLFPNISSSWVHSPSEAGLP
Position: 1-30
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R N1 peptide
Chemical type: Peptide from protein
Sequence: MTLHSNSTTSPLFPNISSSWVHSPSEAGLP
Position: 1-30
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Positive

Epitope: M3R N1 peptide
Chemical type: Peptide from protein
Sequence: MTLHSNSTTSPLFPNISSSWVHSPSEAGLP
Position: 1-30
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R N1 peptide
Chemical type: Peptide from protein
Sequence: MTLHSNSTTSPLFPNISSSWVHSPSEAGLP
Position: 1-30
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R N1 peptide
Chemical type: Peptide from protein
Sequence: MTLHSNSTTSPLFPNISSSWVHSPSEAGLP
Position: 1-30
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R N1 peptide
Chemical type: Peptide from protein
Sequence: MTLHSNSTTSPLFPNISSSWVHSPSEAGLP
Position: 1-30
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R 1st peptide
Chemical type: Peptide from protein
Sequence: FTTYIIMNRWALGNLACDLW
Position: 124-143
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R 1st peptide
Chemical type: Peptide from protein
Sequence: FTTYIIMNRWALGNLACDLW
Position: 124-143
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R 1st peptide
Chemical type: Peptide from protein
Sequence: FTTYIIMNRWALGNLACDLW
Position: 124-143
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R 1st peptide
Chemical type: Peptide from protein
Sequence: FTTYIIMNRWALGNLACDLW
Position: 124-143
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R 1st peptide
Chemical type: Peptide from protein
Sequence: FTTYIIMNRWALGNLACDLW
Position: 124-143
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Positive

Epitope: M3R 1st peptide
Chemical type: Peptide from protein
Sequence: FTTYIIMNRWALGNLACDLW
Position: 124-143
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R 1st peptide
Chemical type: Peptide from protein
Sequence: FTTYIIMNRWALGNLACDLW
Position: 124-143
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R N2 peptide
Chemical type: Peptide from protein
Sequence: VHSPSEAGLPLGTVSQLDSYNISQTSGNFS
Position: 21-50
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R N2 peptide
Chemical type: Peptide from protein
Sequence: VHSPSEAGLPLGTVSQLDSYNISQTSGNFS
Position: 21-50
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R N2 peptide
Chemical type: Peptide from protein
Sequence: VHSPSEAGLPLGTVSQLDSYNISQTSGNFS
Position: 21-50
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R N3 peptide
Chemical type: Peptide from protein
Sequence: NISQTSGNFSSNDTSSDPLGGHTIWQV
Position: 41-67
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R N3 peptide
Chemical type: Peptide from protein
Sequence: NISQTSGNFSSNDTSSDPLGGHTIWQV
Position: 41-67
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R N3 peptide
Chemical type: Peptide from protein
Sequence: NISQTSGNFSSNDTSSDPLGGHTIWQV
Position: 41-67
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R 2nd peptide
Chemical type: Peptide from protein
Sequence: QYFVGKRTVPPGECFIQFLSEP
Position: 207-228
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R 2nd peptide
Chemical type: Peptide from protein
Sequence: QYFVGKRTVPPGECFIQFLSEP
Position: 207-228
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R 2nd peptide
Chemical type: Peptide from protein
Sequence: QYFVGKRTVPPGECFIQFLSEP
Position: 207-228
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R 3rd peptide
Chemical type: Peptide from protein
Sequence: VLVNTFCDSCIPKTYWNLGY
Position: 510-529
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R 3rd peptide
Chemical type: Peptide from protein
Sequence: VLVNTFCDSCIPKTYWNLGY
Position: 510-529
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R 3rd peptide
Chemical type: Peptide from protein
Sequence: VLVNTFCDSCIPKTYWNLGY
Position: 510-529
Source molecule (GenBank): NP_150372.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M3R N1-APL7
Chemical type: Peptide, no natural source
Sequence: TTSPLFPSI
Assay category: TCell
Result: Positive

Epitope: M3R N1-APL5
Chemical type: Peptide, no natural source
Sequence: TTSPLFPTI
Assay category: TCell
Result: Negative

Epitope: M3R N1-APL6
Chemical type: Peptide, no natural source
Sequence: TTSPLFPCI
Assay category: TCell
Result: Negative

Epitope: M3R 1st-APL8
Chemical type: Peptide, no natural source
Sequence: RWALGNLMC
Assay category: TCell
Result: Negative