Reference: Piyada Supasa; Daming Zhou; Wanwisa Dejnirattisai; Chang Liu; Alexander J Mentzer; Helen M Ginn; Yuguang Zhao; Helen M E Duyvesteyn; Rungtiwa Nutalai; Aekkachai Tuekprakhon; Beibei Wang; Guido C Paesen; Jose Slon-Campos; César López-Camacho; Bassam Hallis; Naomi Coombes; Kevin R Bewley; Sue Charlton; Thomas S Walter; Eleanor Barnes; Susanna J Dunachie; Donal Skelly; Sheila F Lumley; Natalie Baker; Imam Shaik; Holly E Humphries; Kerry Godwin; Nick Gent; Alex Sienkiewicz; Christina Dold; Robert Levin; Tao Dong; Andrew J Pollard; Julian C Knight; Paul Klenerman; Derrick Crook; Teresa Lambe; Elizabeth Clutterbuck; Sagida Bibi; Amy Flaxman; Mustapha Bittaye; Sandra Belij-Rammerstorfer; Sarah Gilbert; David R Hall; Mark A Williams; Neil G Paterson; William James; Miles W Carroll; Elizabeth E Fry; Juthathip Mongkolsapaya; Jingshan Ren; David I Stuart; Gavin R Screaton. "Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera." Cell (2021).

Epitope: Epitope of 269 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R403, D405, R408, T415, G416, K417, D420, Y421, Y453, L455, F456, R457, K458, N460, Y473, Q474, A475, G476, S477, F486, N487, Y489, Q493, S494, Y495, G496, Q498, T500, N501, G502, Y505
Source molecule (GenBank): QHR84449.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 269 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R403, D405, R408, T415, G416, K417, D420, Y421, Y453, L455, F456, R457, K458, N460, Y473, Q474, A475, G476, S477, F486, N487, Y489, Q493, S494, Y495, G496, Q498, T500, N501, G502, Y505
Source molecule (GenBank): QHR84449.1
Assay category: BCell
Result: Negative

Epitope: Epitope of 269 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R403, D405, R408, T415, G416, K417, D420, Y421, Y453, L455, F456, R457, K458, N460, Y473, Q474, A475, G476, S477, F486, N487, Y489, Q493, S494, Y495, G496, Q498, T500, N501, G502, Y505
Source molecule (GenBank): QHR84449.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 45.4

Epitope: Epitope of 269 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R403, D405, R408, T415, G416, K417, D420, Y421, Y453, L455, F456, R457, K458, N460, Y473, Q474, A475, G476, S477, F486, N487, Y489, Q493, S494, Y495, G496, Q498, T500, N501, G502, Y505
Source molecule (GenBank): QHR84449.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.77

Epitope: Epitope of 269 Fab on SARS-CoV-2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: R403, D405, R408, T415, G416, K417, D420, Y421, Y453, L455, F456, R457, K458, N460, Y473, Q474, A475, G476, S477, F486, N487, Y489, Q493, S494, Y495, G496, Q498, T500, N501, G502, Y505
Source molecule (GenBank): QHR84449.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.59

Epitope: Epitope of 269 Fab on SARS-CoV-2 RBD N501Y (B.1.1.7)
Chemical type: Discontinuous protein residues
Discontinuous residues: R400, T412, G413, K414, D417, Y418, Y450, L452, F453, R454, K455, N457, Y470, Q471, A472, G473, S474, F483, N484, Y486, Q490, S491, Q495, Y498, G499, Y502
Source molecule (GenBank): QWE88920.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 45.4

Epitope: Epitope of 269 Fab on SARS-CoV-2 RBD N501Y (B.1.1.7)
Chemical type: Discontinuous protein residues
Discontinuous residues: R400, T412, G413, K414, D417, Y418, Y450, L452, F453, R454, K455, N457, Y470, Q471, A472, G473, S474, F483, N484, Y486, Q490, S491, Q495, Y498, G499, Y502
Source molecule (GenBank): QWE88920.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.59

Epitope: Epitope of 269 Fab on SARS-CoV-2 RBD N501Y (B.1.1.7)
Chemical type: Discontinuous protein residues
Discontinuous residues: R400, T412, G413, K414, D417, Y418, Y450, L452, F453, R454, K455, N457, Y470, Q471, A472, G473, S474, F483, N484, Y486, Q490, S491, Q495, Y498, G499, Y502
Source molecule (GenBank): QWE88920.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 269 Fab on SARS-CoV-2 RBD N501Y (B.1.1.7)
Chemical type: Discontinuous protein residues
Discontinuous residues: R400, T412, G413, K414, D417, Y418, Y450, L452, F453, R454, K455, N457, Y470, Q471, A472, G473, S474, F483, N484, Y486, Q490, S491, Q495, Y498, G499, Y502
Source molecule (GenBank): QWE88920.1
Assay category: BCell
Result: Negative

Epitope: Epitope of 269 Fab on SARS-CoV-2 RBD N501Y (B.1.1.7)
Chemical type: Discontinuous protein residues
Discontinuous residues: R400, T412, G413, K414, D417, Y418, Y450, L452, F453, R454, K455, N457, Y470, Q471, A472, G473, S474, F483, N484, Y486, Q490, S491, Q495, Y498, G499, Y502
Source molecule (GenBank): QWE88920.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.19