Reference: M Scotto; G Afonso; E Larger; C Raverdy; F A Lemonnier; J C Carel; D Dubois-Laforgue; B Baz; D Levy; J F Gautier; O Launay; G Bruno; C Boitard; L A Sechi; J C Hutton; H W Davidson; R Mallone. "Zinc transporter (ZnT)8(186-194) is an immunodominant CD8+ T cell epitope in HLA-A2+ type 1 diabetic patients." Diabetologia (2012).

Epitope: 1
Chemical type: Peptide from protein
Sequence: EFLERTYLV
Position: 2-10
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 1
Chemical type: Peptide from protein
Sequence: EFLERTYLV
Position: 2-10
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 2
Chemical type: Peptide from protein
Sequence: VNDKAAKMY
Position: 10-18
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 2
Chemical type: Peptide from protein
Sequence: VNDKAAKMY
Position: 10-18
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 4
Chemical type: Peptide from protein
Sequence: KMYAFTLES
Position: 16-24
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 4
Chemical type: Peptide from protein
Sequence: KMYAFTLES
Position: 16-24
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  22-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 4
Chemical type: Peptide from protein
Sequence: KMYAFTLES
Position: 16-24
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  24-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 4
Chemical type: Peptide from protein
Sequence: KMYAFTLES
Position: 16-24
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 4
Chemical type: Peptide from protein
Sequence: KMYAFTLES
Position: 16-24
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  12-77 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 4
Chemical type: Peptide from protein
Sequence: KMYAFTLES
Position: 16-24
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 5
Chemical type: Peptide from protein
Sequence: MYAFTLESV
Position: 17-25
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 5
Chemical type: Peptide from protein
Sequence: MYAFTLESV
Position: 17-25
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 6
Chemical type: Peptide from protein
Sequence: CPRERPEEL
Position: 37-45
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 6
Chemical type: Peptide from protein
Sequence: CPRERPEEL
Position: 37-45
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 7
Chemical type: Peptide from protein
Sequence: MYHCHSGSK
Position: 50-58
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 7
Chemical type: Peptide from protein
Sequence: MYHCHSGSK
Position: 50-58
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 8
Chemical type: Peptide from protein
Sequence: HSGSKPTEK
Position: 54-62
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 8
Chemical type: Peptide from protein
Sequence: HSGSKPTEK
Position: 54-62
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 9
Chemical type: Peptide from protein
Sequence: PTEKGANEY
Position: 59-67
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 9
Chemical type: Peptide from protein
Sequence: PTEKGANEY
Position: 59-67
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive

Epitope: 10
Chemical type: Peptide from protein
Sequence: EYAYAKWKL
Position: 66-74
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 10
Chemical type: Peptide from protein
Sequence: EYAYAKWKL
Position: 66-74
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 11
Chemical type: Peptide from protein
Sequence: YAKWKLCSA
Position: 69-77
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 11
Chemical type: Peptide from protein
Sequence: YAKWKLCSA
Position: 69-77
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 12
Chemical type: Peptide from protein
Sequence: SAICFIFMI
Position: 78-86
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 12
Chemical type: Peptide from protein
Sequence: SAICFIFMI
Position: 78-86
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 13
Chemical type: Peptide from protein
Sequence: FIFMIAEVV
Position: 82-90
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 13
Chemical type: Peptide from protein
Sequence: FIFMIAEVV
Position: 82-90
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive

Epitope: 14
Chemical type: Peptide from protein
Sequence: VTDAAHLLI
Position: 101-109
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 14
Chemical type: Peptide from protein
Sequence: VTDAAHLLI
Position: 101-109
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive

Epitope: 15
Chemical type: Peptide from protein
Sequence: LLIDLTSFL
Position: 107-115
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 15
Chemical type: Peptide from protein
Sequence: LLIDLTSFL
Position: 107-115
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 16
Chemical type: Peptide from protein
Sequence: LIDLTSFLL
Position: 108-116
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 16
Chemical type: Peptide from protein
Sequence: LIDLTSFLL
Position: 108-116
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 17
Chemical type: Peptide from protein
Sequence: LTSFLLSLF
Position: 111-119
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 17
Chemical type: Peptide from protein
Sequence: LTSFLLSLF
Position: 111-119
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 18
Chemical type: Peptide from protein
Sequence: SFLLSLFSL
Position: 113-121
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 18
Chemical type: Peptide from protein
Sequence: SFLLSLFSL
Position: 113-121
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive

Epitope: 19
Chemical type: Peptide from protein
Sequence: LLSLFSLWL
Position: 115-123
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 19
Chemical type: Peptide from protein
Sequence: LLSLFSLWL
Position: 115-123
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive

Epitope: 20
Chemical type: Peptide from protein
Sequence: LFSLWLSSK
Position: 118-126
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 20
Chemical type: Peptide from protein
Sequence: LFSLWLSSK
Position: 118-126
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 21
Chemical type: Peptide from protein
Sequence: WLSSKPPSK
Position: 122-130
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 21
Chemical type: Peptide from protein
Sequence: WLSSKPPSK
Position: 122-130
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 22
Chemical type: Peptide from protein
Sequence: LSSKPPSKR
Position: 123-131
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 22
Chemical type: Peptide from protein
Sequence: LSSKPPSKR
Position: 123-131
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 23
Chemical type: Peptide from protein
Sequence: KPPSKRLTF
Position: 126-134
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 23
Chemical type: Peptide from protein
Sequence: KPPSKRLTF
Position: 126-134
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 24
Chemical type: Peptide from protein
Sequence: FGWHRAEIL
Position: 134-142
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 24
Chemical type: Peptide from protein
Sequence: FGWHRAEIL
Position: 134-142
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 25
Chemical type: Peptide from protein
Sequence: ILGALLSIL
Position: 141-149
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 25
Chemical type: Peptide from protein
Sequence: ILGALLSIL
Position: 141-149
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 26
Chemical type: Peptide from protein
Sequence: LLSILCIWV
Position: 145-153
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 26
Chemical type: Peptide from protein
Sequence: LLSILCIWV
Position: 145-153
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive

Epitope: 27
Chemical type: Peptide from protein
Sequence: IWVVTGVLV
Position: 151-159
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 27
Chemical type: Peptide from protein
Sequence: IWVVTGVLV
Position: 151-159
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 28
Chemical type: Peptide from protein
Sequence: WVVTGVLVY
Position: 152-160
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 28
Chemical type: Peptide from protein
Sequence: WVVTGVLVY
Position: 152-160
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 29
Chemical type: Peptide from protein
Sequence: VVTGVLVYL
Position: 153-161
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 29
Chemical type: Peptide from protein
Sequence: VVTGVLVYL
Position: 153-161
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  24-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 29
Chemical type: Peptide from protein
Sequence: VVTGVLVYL
Position: 153-161
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  12-77 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 29
Chemical type: Peptide from protein
Sequence: VVTGVLVYL
Position: 153-161
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 29
Chemical type: Peptide from protein
Sequence: VVTGVLVYL
Position: 153-161
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  22-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 29
Chemical type: Peptide from protein
Sequence: VVTGVLVYL
Position: 153-161
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 30
Chemical type: Peptide from protein
Sequence: VYLACERLL
Position: 159-167
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 30
Chemical type: Peptide from protein
Sequence: VYLACERLL
Position: 159-167
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 31
Chemical type: Peptide from protein
Sequence: YLACERLLY
Position: 160-168
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 31
Chemical type: Peptide from protein
Sequence: YLACERLLY
Position: 160-168
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 32
Chemical type: Peptide from protein
Sequence: RLLYPDYQI
Position: 165-173
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 32
Chemical type: Peptide from protein
Sequence: RLLYPDYQI
Position: 165-173
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  24-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 32
Chemical type: Peptide from protein
Sequence: RLLYPDYQI
Position: 165-173
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  22-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 32
Chemical type: Peptide from protein
Sequence: RLLYPDYQI
Position: 165-173
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  12-77 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 32
Chemical type: Peptide from protein
Sequence: RLLYPDYQI
Position: 165-173
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 32
Chemical type: Peptide from protein
Sequence: RLLYPDYQI
Position: 165-173
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 33
Chemical type: Peptide from protein
Sequence: DYQIQATVM
Position: 170-178
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 33
Chemical type: Peptide from protein
Sequence: DYQIQATVM
Position: 170-178
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 34
Chemical type: Peptide from protein
Sequence: YQIQATVMI
Position: 171-179
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 34
Chemical type: Peptide from protein
Sequence: YQIQATVMI
Position: 171-179
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 35
Chemical type: Peptide from protein
Sequence: IQATVMIIV
Position: 173-181
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 35
Chemical type: Peptide from protein
Sequence: IQATVMIIV
Position: 173-181
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  24-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 35
Chemical type: Peptide from protein
Sequence: IQATVMIIV
Position: 173-181
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  22-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 35
Chemical type: Peptide from protein
Sequence: IQATVMIIV
Position: 173-181
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  12-77 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 35
Chemical type: Peptide from protein
Sequence: IQATVMIIV
Position: 173-181
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 35
Chemical type: Peptide from protein
Sequence: IQATVMIIV
Position: 173-181
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 36
Chemical type: Peptide from protein
Sequence: MIIVSSCAV
Position: 178-186
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 36
Chemical type: Peptide from protein
Sequence: MIIVSSCAV
Position: 178-186
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 37
Chemical type: Peptide from protein
Sequence: VAANIVLTV
Position: 186-194
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 37
Chemical type: Peptide from protein
Sequence: VAANIVLTV
Position: 186-194
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  24-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 37
Chemical type: Peptide from protein
Sequence: VAANIVLTV
Position: 186-194
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  12-77 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 37
Chemical type: Peptide from protein
Sequence: VAANIVLTV
Position: 186-194
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  22-60 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 37
Chemical type: Peptide from protein
Sequence: VAANIVLTV
Position: 186-194
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  1-16 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 37
Chemical type: Peptide from protein
Sequence: VAANIVLTV
Position: 186-194
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 38
Chemical type: Peptide from protein
Sequence: VLTVVLHQR
Position: 191-199
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 38
Chemical type: Peptide from protein
Sequence: VLTVVLHQR
Position: 191-199
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 39
Chemical type: Peptide from protein
Sequence: VRAAFVHAL
Position: 214-222
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 39
Chemical type: Peptide from protein
Sequence: VRAAFVHAL
Position: 214-222
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 40
Chemical type: Peptide from protein
Sequence: ALGDLFQSI
Position: 221-229
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 40
Chemical type: Peptide from protein
Sequence: ALGDLFQSI
Position: 221-229
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  12-77 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 40
Chemical type: Peptide from protein
Sequence: ALGDLFQSI
Position: 221-229
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  22-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 40
Chemical type: Peptide from protein
Sequence: ALGDLFQSI
Position: 221-229
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 40
Chemical type: Peptide from protein
Sequence: ALGDLFQSI
Position: 221-229
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 41
Chemical type: Peptide from protein
Sequence: LFQSISVLI
Position: 225-233
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 41
Chemical type: Peptide from protein
Sequence: LFQSISVLI
Position: 225-233
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 42
Chemical type: Peptide from protein
Sequence: SISVLISAL
Position: 228-236
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 42
Chemical type: Peptide from protein
Sequence: SISVLISAL
Position: 228-236
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 43
Chemical type: Peptide from protein
Sequence: ISVLISALI
Position: 229-237
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 43
Chemical type: Peptide from protein
Sequence: ISVLISALI
Position: 229-237
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 44
Chemical type: Peptide from protein
Sequence: VLISALIIY
Position: 231-239
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 44
Chemical type: Peptide from protein
Sequence: VLISALIIY
Position: 231-239
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 45
Chemical type: Peptide from protein
Sequence: ISALIIYFK
Position: 233-241
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 45
Chemical type: Peptide from protein
Sequence: ISALIIYFK
Position: 233-241
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 46
Chemical type: Peptide from protein
Sequence: IIYFKPEYK
Position: 237-245
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 46
Chemical type: Peptide from protein
Sequence: IIYFKPEYK
Position: 237-245
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive

Epitope: 48
Chemical type: Peptide from protein
Sequence: CTFIFSILV
Position: 251-259
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 48
Chemical type: Peptide from protein
Sequence: CTFIFSILV
Position: 251-259
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive

Epitope: 49
Chemical type: Peptide from protein
Sequence: TFIFSILVL
Position: 252-260
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 49
Chemical type: Peptide from protein
Sequence: TFIFSILVL
Position: 252-260
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 50
Chemical type: Peptide from protein
Sequence: FIFSILVLA
Position: 253-261
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 50
Chemical type: Peptide from protein
Sequence: FIFSILVLA
Position: 253-261
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  24-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 50
Chemical type: Peptide from protein
Sequence: FIFSILVLA
Position: 253-261
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  12-77 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 50
Chemical type: Peptide from protein
Sequence: FIFSILVLA
Position: 253-261
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  22-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 50
Chemical type: Peptide from protein
Sequence: FIFSILVLA
Position: 253-261
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 50
Chemical type: Peptide from protein
Sequence: FIFSILVLA
Position: 253-261
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 51
Chemical type: Peptide from protein
Sequence: LVLASTITI
Position: 258-266
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 51
Chemical type: Peptide from protein
Sequence: LVLASTITI
Position: 258-266
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 52
Chemical type: Peptide from protein
Sequence: VLASTITIL
Position: 259-267
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 52
Chemical type: Peptide from protein
Sequence: VLASTITIL
Position: 259-267
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 53
Chemical type: Peptide from protein
Sequence: LASTITILK
Position: 260-268
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 53
Chemical type: Peptide from protein
Sequence: LASTITILK
Position: 260-268
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive

Epitope: 54
Chemical type: Peptide from protein
Sequence: ILKDFSILL
Position: 266-274
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 54
Chemical type: Peptide from protein
Sequence: ILKDFSILL
Position: 266-274
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  24-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 54
Chemical type: Peptide from protein
Sequence: ILKDFSILL
Position: 266-274
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  22-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 54
Chemical type: Peptide from protein
Sequence: ILKDFSILL
Position: 266-274
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 54
Chemical type: Peptide from protein
Sequence: ILKDFSILL
Position: 266-274
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  12-77 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 54
Chemical type: Peptide from protein
Sequence: ILKDFSILL
Position: 266-274
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 55
Chemical type: Peptide from protein
Sequence: ILLMEGVPK
Position: 272-280
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 55
Chemical type: Peptide from protein
Sequence: ILLMEGVPK
Position: 272-280
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 56
Chemical type: Peptide from protein
Sequence: LLMEGVPKS
Position: 273-281
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 56
Chemical type: Peptide from protein
Sequence: LLMEGVPKS
Position: 273-281
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 57
Chemical type: Peptide from protein
Sequence: KSLNYSGVK
Position: 280-288
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 57
Chemical type: Peptide from protein
Sequence: KSLNYSGVK
Position: 280-288
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  22-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 57
Chemical type: Peptide from protein
Sequence: KSLNYSGVK
Position: 280-288
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  24-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 57
Chemical type: Peptide from protein
Sequence: KSLNYSGVK
Position: 280-288
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  12-77 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 57
Chemical type: Peptide from protein
Sequence: KSLNYSGVK
Position: 280-288
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 57
Chemical type: Peptide from protein
Sequence: KSLNYSGVK
Position: 280-288
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 58
Chemical type: Peptide from protein
Sequence: NYSGVKELI
Position: 283-291
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 58
Chemical type: Peptide from protein
Sequence: NYSGVKELI
Position: 283-291
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 59
Chemical type: Peptide from protein
Sequence: LAVDGVLSV
Position: 292-300
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 59
Chemical type: Peptide from protein
Sequence: LAVDGVLSV
Position: 292-300
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive

Epitope: 60
Chemical type: Peptide from protein
Sequence: VLSVHSLHI
Position: 297-305
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 60
Chemical type: Peptide from protein
Sequence: VLSVHSLHI
Position: 297-305
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 61
Chemical type: Peptide from protein
Sequence: SLHIWSLTM
Position: 302-310
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 61
Chemical type: Peptide from protein
Sequence: SLHIWSLTM
Position: 302-310
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive

Epitope: 62
Chemical type: Peptide from protein
Sequence: IWSLTMNQV
Position: 305-313
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 62
Chemical type: Peptide from protein
Sequence: IWSLTMNQV
Position: 305-313
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 64
Chemical type: Peptide from protein
Sequence: ILSAHVATA
Position: 314-322
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 64
Chemical type: Peptide from protein
Sequence: ILSAHVATA
Position: 314-322
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High

Epitope: 65
Chemical type: Peptide from protein
Sequence: VRREIAKAL
Position: 330-338
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 65
Chemical type: Peptide from protein
Sequence: VRREIAKAL
Position: 330-338
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 66
Chemical type: Peptide from protein
Sequence: REIAKALSK
Position: 332-340
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 66
Chemical type: Peptide from protein
Sequence: REIAKALSK
Position: 332-340
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 67
Chemical type: Peptide from protein
Sequence: IAKALSKSF
Position: 334-342
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 67
Chemical type: Peptide from protein
Sequence: IAKALSKSF
Position: 334-342
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 68
Chemical type: Peptide from protein
Sequence: ALSKSFTMH
Position: 337-345
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 68
Chemical type: Peptide from protein
Sequence: ALSKSFTMH
Position: 337-345
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 69
Chemical type: Peptide from protein
Sequence: SFTMHSLTI
Position: 341-349
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 69
Chemical type: Peptide from protein
Sequence: SFTMHSLTI
Position: 341-349
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Negative

Epitope: 70
Chemical type: Peptide from protein
Sequence: TMHSLTIQM
Position: 343-351
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  24-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 70
Chemical type: Peptide from protein
Sequence: TMHSLTIQM
Position: 343-351
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  22-60 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 70
Chemical type: Peptide from protein
Sequence: TMHSLTIQM
Position: 343-351
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Negative
Host:  12-77 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 70
Chemical type: Peptide from protein
Sequence: TMHSLTIQM
Position: 343-351
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 70
Chemical type: Peptide from protein
Sequence: TMHSLTIQM
Position: 343-351
Source molecule (GenBank): NP_776250.2
Assay category: TCell
Result: Positive
Host:  1-16 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: 70
Chemical type: Peptide from protein
Sequence: TMHSLTIQM
Position: 343-351
Source molecule (GenBank): NP_776250.2
Assay category: MhcBinding
Result: Positive-High