Reference: Serena Stadler; Rafael B Blasco; Vijay Kumar Singh; Christine Damm-Welk; Amin Ben-Hamza; Carlotta Welters; Leo Hansmann; Roberto Chiarle; Wilhelm Woessmann. "Endogenous CD4+ T Cells That Recognize ALK and the NPM1::ALK Fusion Protein Can Be Expanded from Human Peripheral Blood." Cancer immunology research (2025).

Epitope: NT1
Chemical type: Peptide from protein
Sequence: VVYRRKHQELQAMQMELQSPEYKLSKLRTS
Position: 117-146
Source molecule (GenBank): BAA08343.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NT2
Chemical type: Peptide from protein
Sequence: MELQSPEYKLSKLRTSTIMTDYNPNYCFAG
Position: 1071-1100
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A1
Chemical type: Peptide from protein
Sequence: RKNITLIRGLGHGAFGEVYEGQVSGMPNDP
Position: 1113-1142
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A2
Chemical type: Peptide from protein
Sequence: FGEVYEGQVSGMPNDPSPLQVAVKTLPEVC
Position: 1127-1156
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A3
Chemical type: Peptide from protein
Sequence: DPSPLQVAVKTLPEVCSEQDELDFLMEALI
Position: 1141-1170
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A4
Chemical type: Peptide from protein
Sequence: VCSEQDELDFLMEALIISKFNHQNIVRCIG
Position: 1155-1184
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A5
Chemical type: Peptide from protein
Sequence: LIISKFNHQNIVRCIGVSLQSLPRFILLEL
Position: 1169-1198
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B1
Chemical type: Peptide from protein
Sequence: ELMAGGDLKSFLRETRPRPSQPSSLAMLDL
Position: 1197-1226
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B2
Chemical type: Peptide from protein
Sequence: TRPRPSQPSSLAMLDLLHVARDIACGCQYL
Position: 1211-1240
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B3
Chemical type: Peptide from protein
Sequence: DLLHVARDIACGCQYLEENHFIHRDIAARN
Position: 1225-1254
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B4
Chemical type: Peptide from protein
Sequence: YLEENHFIHRDIAARNCLLTCPGPGRVAKI
Position: 1239-1268
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B5
Chemical type: Peptide from protein
Sequence: RNCLLTCPGPGRVAKIGDFGMARDIYRASY
Position: 1253-1282
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B6
Chemical type: Peptide from protein
Sequence: KIGDFGMARDIYRASYYRKGGCAMLPVKWM
Position: 1267-1296
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B2_B2
Chemical type: Peptide from protein
Sequence: GDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGC
Position: 1202-1237
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B2_B3
Chemical type: Peptide from protein
Sequence: LLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG
Position: 1226-1261
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B2_B4
Chemical type: Peptide from protein
Sequence: IAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRK
Position: 1250-1285
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: B2_B5
Chemical type: Peptide from protein
Sequence: ARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSK
Position: 1274-1309
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C1
Chemical type: Peptide from protein
Sequence: SYYRKGGCAMLPVKWMPPEAFMEGIFTSKT
Position: 1281-1310
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C2
Chemical type: Peptide from protein
Sequence: WMPPEAFMEGIFTSKTDTWSFGVLLWEIFS
Position: 1295-1324
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C3
Chemical type: Peptide from protein
Sequence: KTDTWSFGVLLWEIFSLGYMPYPSKSNQEV
Position: 1309-1338
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C4
Chemical type: Peptide from protein
Sequence: FSLGYMPYPSKSNQEVLEFVTSGGRMDPPK
Position: 1323-1352
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C5
Chemical type: Peptide from protein
Sequence: EVLEFVTSGGRMDPPKNCPGPVYRIMTQCW
Position: 1337-1366
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: D1
Chemical type: Peptide from protein
Sequence: CWQHQPEDRPNFAIILERIEYCTQDPDVIN
Position: 1365-1394
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: D2
Chemical type: Peptide from protein
Sequence: ILERIEYCTQDPDVINTALPIEYGPLVEEE
Position: 1379-1408
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: D3
Chemical type: Peptide from protein
Sequence: INTALPIEYGPLVEEEEKVPVRPKDPEGVP
Position: 1393-1422
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: D4
Chemical type: Peptide from protein
Sequence: EEEKVPVRPKDPEGVPPLLVSQQAKREEER
Position: 1407-1436
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: D5
Chemical type: Peptide from protein
Sequence: VPPLLVSQQAKREEERSPAAPPPLPTTSSG
Position: 1421-1450
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: D6
Chemical type: Peptide from protein
Sequence: ERSPAAPPPLPTTSSGKAAKKPTAAEVSVR
Position: 1441-1470
Source molecule (GenBank): BAD92714.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CT1
Chemical type: Peptide from protein
Sequence: LGLEGSCTVPPNVATGRLPGASLLLEPSSL
Position: 1533-1562
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CT3
Chemical type: Peptide from protein
Sequence: SLTANMKEVPLFRLRHFPCGNVNYGYQQQG
Position: 1561-1590
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CT6
Chemical type: Peptide from protein
Sequence: HYEDTILKSKNSMNQPGP
Position: 1603-1620
Source molecule (GenBank): Q9UM73.3
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Fusion 15mer
Chemical type: Peptide, no natural source
Sequence: SGQHLVVYRRKHQEL
Assay category: TCell
Result: Negative
Host: M 
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Fusion 15mer
Chemical type: Peptide, no natural source
Sequence: SGQHLVVYRRKHQEL
Assay category: TCell
Result: Negative
Host: M 
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Fusion 15mer
Chemical type: Peptide, no natural source
Sequence: SGQHLVVYRRKHQEL
Assay category: TCell
Result: Negative
Host: M 
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Fusion 15mer
Chemical type: Peptide, no natural source
Sequence: SGQHLVVYRRKHQEL
Assay category: TCell
Result: Negative
Host: M 
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Fusion 15mer
Chemical type: Peptide, no natural source
Sequence: SGQHLVVYRRKHQEL
Assay category: TCell
Result: Negative
Host: M 
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Fusion 15mer
Chemical type: Peptide, no natural source
Sequence: SGQHLVVYRRKHQEL
Assay category: TCell
Result: Negative
Host: M 
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Fusion 15mer
Chemical type: Peptide, no natural source
Sequence: SGQHLVVYRRKHQEL
Assay category: TCell
Result: Negative
Host: M 
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Fusion 15mer
Chemical type: Peptide, no natural source
Sequence: SGQHLVVYRRKHQEL
Assay category: TCell
Result: Positive
Host: M 
Cell type: T cell CD4+
Tissue: lymphoid
Culture conditions: Engineered

Epitope: Fusion 15mer
Chemical type: Peptide, no natural source
Sequence: SGQHLVVYRRKHQEL
Assay category: TCell
Result: Positive
Host: M 
Cell type: T cell CD4+
Tissue: lymphoid
Culture conditions: Engineered

Epitope: Fusion 15mer
Chemical type: Peptide, no natural source
Sequence: SGQHLVVYRRKHQEL
Assay category: TCell
Result: Positive
Host: M 
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: Fusion 15mer
Chemical type: Peptide, no natural source
Sequence: SGQHLVVYRRKHQEL
Assay category: TCell
Result: Positive
Host: M 
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: Fusion 15mer
Chemical type: Peptide, no natural source
Sequence: SGQHLVVYRRKHQEL
Assay category: TCell
Result: Negative
Host: M 
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Fusion 15mer
Chemical type: Peptide, no natural source
Sequence: SGQHLVVYRRKHQEL
Assay category: TCell
Result: Negative
Host: M 
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Fusion 15mer
Chemical type: Peptide, no natural source
Sequence: SGQHLVVYRRKHQEL
Assay category: TCell
Result: Negative
Host: M 
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated