Reference: Marije B Overdijk; Kristin Strumane; Frank J Beurskens; Antonio Ortiz Buijsse; Claudine Vermot-Desroches; Boris S Vuillermoz; Thessa Kroes; Bart de Jong; Naomi Hoevenaars; Richard G Hibbert; Andreas Lingnau; Ulf Forssmann; Janine Schuurman; Paul W H I Parren; Rob N de Jong; Esther C W Breij. "Dual Epitope Targeting and Enhanced Hexamerization by DR5 Antibodies as a Novel Approach to Induce Potent Antitumor Activity Through DR5 Agonism." Molecular cancer therapeutics (2020).

Epitope: Epitope of IgG1-DR5-01 Fab on Death receptor 5
Chemical type: Discontinuous protein residues
Discontinuous residues: R115, D120, S121, G122, E141, T143, E146, P150, M152, C153, R154, K155, R157, T158
Source molecule (GenBank): O14763.2
Assay category: BCell
Result: Positive
Quantitative measurement: 430000.0

Epitope: Epitope of IgG1-DR5-01 Fab on Death receptor 5
Chemical type: Discontinuous protein residues
Discontinuous residues: R115, D120, S121, G122, E141, T143, E146, P150, M152, C153, R154, K155, R157, T158
Source molecule (GenBank): O14763.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0055

Epitope: Epitope of IgG1-DR5-01 Fab on Death receptor 5
Chemical type: Discontinuous protein residues
Discontinuous residues: R115, D120, S121, G122, E141, T143, E146, P150, M152, C153, R154, K155, R157, T158
Source molecule (GenBank): O14763.2
Assay category: BCell
Result: Positive
Quantitative measurement: 12.8

Epitope: Epitope of IgG1-DR5-01 Fab on Death receptor 5
Chemical type: Discontinuous protein residues
Discontinuous residues: R115, D120, S121, G122, E141, T143, E146, P150, M152, C153, R154, K155, R157, T158
Source molecule (GenBank): O14763.2
Assay category: BCell
Result: Positive

Epitope: Epitope of IgG1-DR5-01 Fab on Death receptor 5
Chemical type: Discontinuous protein residues
Discontinuous residues: R115, D120, S121, G122, E141, T143, E146, P150, M152, C153, R154, K155, R157, T158
Source molecule (GenBank): O14763.2
Assay category: BCell
Result: Positive

Epitope: Epitope of IgG1-DR5-01 Fab on Death receptor 5
Chemical type: Discontinuous protein residues
Discontinuous residues: R115, D120, S121, G122, E141, T143, E146, P150, M152, C153, R154, K155, R157, T158
Source molecule (GenBank): O14763.2
Assay category: BCell
Result: Positive
Quantitative measurement: 3.05

Epitope: Epitope of IgG1-DR5-05 Fab on Death receptor 5
Chemical type: Discontinuous protein residues
Discontinuous residues: S74, S75, P76, G79, L80, I87, E89, D90, G91, H106, D109, L110, L111, F112
Source molecule (GenBank): O14763.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.013

Epitope: Epitope of IgG1-DR5-05 Fab on Death receptor 5
Chemical type: Discontinuous protein residues
Discontinuous residues: S74, S75, P76, G79, L80, I87, E89, D90, G91, H106, D109, L110, L111, F112
Source molecule (GenBank): O14763.2
Assay category: BCell
Result: Positive

Epitope: Epitope of IgG1-DR5-05 Fab on Death receptor 5
Chemical type: Discontinuous protein residues
Discontinuous residues: S74, S75, P76, G79, L80, I87, E89, D90, G91, H106, D109, L110, L111, F112
Source molecule (GenBank): O14763.2
Assay category: BCell
Result: Positive

Epitope: Epitope of IgG1-DR5-05 Fab on Death receptor 5
Chemical type: Discontinuous protein residues
Discontinuous residues: S74, S75, P76, G79, L80, I87, E89, D90, G91, H106, D109, L110, L111, F112
Source molecule (GenBank): O14763.2
Assay category: BCell
Result: Positive
Quantitative measurement: 3.05

Epitope: Epitope of IgG1-DR5-05 Fab on Death receptor 5
Chemical type: Discontinuous protein residues
Discontinuous residues: S74, S75, P76, G79, L80, I87, E89, D90, G91, H106, D109, L110, L111, F112
Source molecule (GenBank): O14763.2
Assay category: BCell
Result: Positive
Quantitative measurement: 28.5

Epitope: Epitope of IgG1-DR5-05 Fab on Death receptor 5
Chemical type: Discontinuous protein residues
Discontinuous residues: S74, S75, P76, G79, L80, I87, E89, D90, G91, H106, D109, L110, L111, F112
Source molecule (GenBank): O14763.2
Assay category: BCell
Result: Positive
Quantitative measurement: 440000.0