Reference: Christabel Kelly; Leo Swadling; Stefania Capone; Anthony Brown; Rachel Richardson; John Halliday; Annette von Delft; Ye Oo; David Mutimer; Ayako Kurioka; Felicity Hartnell; Jane Collier; Virginia Ammendola; Mariarosaria Del Sorbo; Fabiana Grazioli; Maria Luisa Esposito; Stefania Di Marco; Loredana Siani; Cinzia Traboni; Adrian V S Hill; Stefano Colloca; Alfredo Nicosia; Riccardo Cortese; Antonella Folgori; Paul Klenerman; Eleanor Barnes. "Chronic hepatitis C viral infection subverts vaccine-induced T-cell immunity in humans." Hepatology (Baltimore, Md.) (2016).

Epitope: HCV BK (1073-1081)
Chemical type: Peptide from protein
Sequence: CVNGVCWTV
Position: 1073-1081
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1073-1081)
Chemical type: Peptide from protein
Sequence: CVNGVCWTV
Position: 1073-1081
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1073-1081)
Chemical type: Peptide from protein
Sequence: CVNGVCWTV
Position: 1073-1081
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1406-1415)
Chemical type: Peptide from protein
Sequence: KLSGLGINAV
Position: 1406-1415
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive-Low
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1406-1415)
Chemical type: Peptide from protein
Sequence: KLSGLGINAV
Position: 1406-1415
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1406-1415)
Chemical type: Peptide from protein
Sequence: KLSGLGINAV
Position: 1406-1415
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive-Low
Host:  18-65 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1406-1415)
Chemical type: Peptide from protein
Sequence: KLSGLGINAV
Position: 1406-1415
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1406-1415)
Chemical type: Peptide from protein
Sequence: KLSGLGINAV
Position: 1406-1415
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1675-1689)
Chemical type: Peptide from protein
Sequence: LTTGSVVIVGRIILS
Position: 1675-1689
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1675-1689)
Chemical type: Peptide from protein
Sequence: LTTGSVVIVGRIILS
Position: 1675-1689
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1679-1693)
Chemical type: Peptide from protein
Sequence: SVVIVGRIILSGRPA
Position: 1679-1693
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1679-1693)
Chemical type: Peptide from protein
Sequence: SVVIVGRIILSGRPA
Position: 1679-1693
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1703-1717)
Chemical type: Peptide from protein
Sequence: QEFDEMEECASHLPY
Position: 1703-1717
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1851-1865)
Chemical type: Peptide from protein
Sequence: ILAGYGAGVAGALVA
Position: 1851-1865
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (2587-2601)
Chemical type: Peptide from protein
Sequence: RVCEKMALYDVVSTL
Position: 2587-2601
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (2071-2085)
Chemical type: Peptide from protein
Sequence: TPSPAPNYSRALWRV
Position: 2071-2085
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (2075-2089)
Chemical type: Peptide from protein
Sequence: APNYSRALWRVAAEE
Position: 2075-2089
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (2147-2161)
Chemical type: Peptide from protein
Sequence: FQVGLNQYLVGSQLP
Position: 2147-2161
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (2983-2997)
Chemical type: Peptide from protein
Sequence: LSRARPRWFMLCLLL
Position: 2983-2997
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1395-1403)
Chemical type: Peptide from protein
Sequence: HSKKKCDEL
Position: 1395-1403
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host: F 35 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1635-1649)
Chemical type: Peptide from protein
Sequence: VTLTHPITKYIMACM
Position: 1635-1649
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (2840-2848)
Chemical type: Peptide from protein
Sequence: ARMILMTHF
Position: 2840-2848
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (2840-2848)
Chemical type: Peptide from protein
Sequence: ARMILMTHF
Position: 2840-2848
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (2803-2812)
Chemical type: Peptide from protein
Sequence: LTRDPTTPLA
Position: 2803-2812
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host: M 35 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (2803-2812)
Chemical type: Peptide from protein
Sequence: LTRDPTTPLA
Position: 2803-2812
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1411-1425)
Chemical type: Peptide from protein
Sequence: GINAVAYYRGLDVSV
Position: 1411-1425
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host: M 59 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1891-1899)
Chemical type: Peptide from protein
Sequence: ALVVGVVCA
Position: 1891-1899
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1891-1899)
Chemical type: Peptide from protein
Sequence: ALVVGVVCA
Position: 1891-1899
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (1406-1415)
Chemical type: Peptide from protein
Sequence: KLVALGINAV
Position: 1406-1415
Source molecule (GenBank): AAA45534.1
Assay category: TCell
Result: Negative
Host: M 35-50 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (1406-1415)
Chemical type: Peptide from protein
Sequence: KLVAMGVNAV
Position: 1406-1415
Source molecule (GenBank): AAY29640.1
Assay category: TCell
Result: Negative
Host: M 35-50 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (32-41)
Chemical type: Peptide from protein
Sequence: KLVSLGLNAV
Position: 32-41
Source molecule (GenBank): AAS18644.1
Assay category: TCell
Result: Negative
Host: M 35-50 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (1395-1403)
Chemical type: Peptide from protein
Sequence: HSKRKCDEL
Position: 1395-1403
Source molecule (GenBank): AAY82032.1
Assay category: TCell
Result: Negative
Host: F 35 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (2811-2821)
Chemical type: Peptide from protein
Sequence: LTRDPITPLAR
Position: 2811-2821
Source molecule (GenBank): ABX80367.1
Assay category: TCell
Result: Negative
Host: M 35 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (1073-1081)
Chemical type: Peptide from protein
Sequence: CINGVCWTV
Position: 1073-1081
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive
Host:  33-49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (1073-1081)
Chemical type: Peptide from protein
Sequence: CINGVCWTV
Position: 1073-1081
Source molecule (GenBank): BAA01582.1
Assay category: TCell
Result: Positive-Low
Host:  33-49 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV (1415-1429)
Chemical type: Peptide from protein
Sequence: GVNAVAYYRGLDVSV
Position: 1415-1429
Source molecule (GenBank): BAA01761.1
Assay category: TCell
Result: Positive
Host: M 59 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1851-1859)
Chemical type: Peptide from protein
Sequence: ILAGYGAGV
Position: 1851-1859
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1636-1643)
Chemical type: Peptide from protein
Sequence: TLTHPITK
Position: 1636-1643
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Positive
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1888-1896)
Chemical type: Peptide from protein
Sequence: SPGALVVGV
Position: 1888-1896
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Negative
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (2803-2811)
Chemical type: Peptide from protein
Sequence: LTRDPTTPL
Position: 2803-2811
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Negative
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV BK (1887-1896)
Chemical type: Peptide from protein
Sequence: LSPGALVVGV
Position: 1887-1896
Source molecule (GenBank): AAA72945.1
Assay category: TCell
Result: Negative
Host:  18-65 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo