Reference: Eleni Tiniakou; Alex Girgis; Tiara Siafei; Jemima Albayda; Brittany Adler; Julie J Paik; Christopher A Mecoli; Alison Rebman; Mark J Soloski; Lisa Christopher-Stine; Kellie N Smith; Antony Rosen; Andrew Lee Mammen; Erika Darrah. "Precise identification and tracking of HMGCR-reactive CD4+ T cells in the target tissue of patients with anti-HMGCR immune-mediated necrotising myopathy." Annals of the rheumatic diseases (2025).

Epitope: ERKVEVIKPLVAETDTPNR
Chemical type: Peptide from protein
Sequence: ERKVEVIKPLVAETDTPNR
Position: 394-412
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 416 422

Epitope: KVEVIKPLVAETDTPN
Chemical type: Peptide from protein
Sequence: KVEVIKPLVAETDTPN
Position: 396-411
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 416 422

Epitope: ETDTPNRATFVVGNSSLLDTSS
Chemical type: Peptide from protein
Sequence: ETDTPNRATFVVGNSSLLDTSS
Position: 406-427
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 416 422

Epitope: DTPNRATFVVGNSSLLDTSS
Chemical type: Peptide from protein
Sequence: DTPNRATFVVGNSSLLDTSS
Position: 408-427
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 419 52

Epitope: TPNRATFVVGNSSLLDT
Chemical type: Peptide from protein
Sequence: TPNRATFVVGNSSLLDT
Position: 409-425
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 419 52

Epitope: TPNRATFVVGNSSLLDTS
Chemical type: Peptide from protein
Sequence: TPNRATFVVGNSSLLDTS
Position: 409-426
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 419 52

Epitope: VGNSSLLDTSSVLVTQEPE
Chemical type: Peptide from protein
Sequence: VGNSSLLDTSSVLVTQEPE
Position: 417-435
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: NSSLLDTSSVLVTQEP
Chemical type: Peptide from protein
Sequence: NSSLLDTSSVLVTQEP
Position: 419-434
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: SSLLDTSSVLVTQEP
Chemical type: Peptide from protein
Sequence: SSLLDTSSVLVTQEP
Position: 420-434
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: SDAEIIQLVNAKHIPA
Chemical type: Peptide from protein
Sequence: SDAEIIQLVNAKHIPA
Position: 463-478
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: SDAEIIQLVNAKHIPAYK
Chemical type: Peptide from protein
Sequence: SDAEIIQLVNAKHIPAYK
Position: 463-480
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: SDAEIIQLVNAKHIPAYK
Chemical type: Peptide from protein
Sequence: SDAEIIQLVNAKHIPAYK
Position: 463-480
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 416 422

Epitope: DAEIIQLVNAKHIPA
Chemical type: Peptide from protein
Sequence: DAEIIQLVNAKHIPA
Position: 464-478
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 419 413

Epitope: DAEIIQLVNAKHIPA
Chemical type: Peptide from protein
Sequence: DAEIIQLVNAKHIPA
Position: 464-478
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: DAEIIQLVNAKHIPAY
Chemical type: Peptide from protein
Sequence: DAEIIQLVNAKHIPAY
Position: 464-479
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: DAEIIQLVNAKHIPAY
Chemical type: Peptide from protein
Sequence: DAEIIQLVNAKHIPAY
Position: 464-479
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 419 413

Epitope: DAEIIQLVNAKHIPAYK
Chemical type: Peptide from protein
Sequence: DAEIIQLVNAKHIPAYK
Position: 464-480
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: DAEIIQLVNAKHIPAYK
Chemical type: Peptide from protein
Sequence: DAEIIQLVNAKHIPAYK
Position: 464-480
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 419 52

Epitope: DAEIIQLVNAKHIPAYK
Chemical type: Peptide from protein
Sequence: DAEIIQLVNAKHIPAYK
Position: 464-480
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 416 422

Epitope: DAEIIQLVNAKHIPAYK
Chemical type: Peptide from protein
Sequence: DAEIIQLVNAKHIPAYK
Position: 464-480
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 436 422

Epitope: DAEIIQLVNAKHIPAYK
Chemical type: Peptide from protein
Sequence: DAEIIQLVNAKHIPAYK
Position: 464-480
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 419 413

Epitope: IIQLVNAKHIPA
Chemical type: Peptide from protein
Sequence: IIQLVNAKHIPA
Position: 467-478
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: IIQLVNAKHIPAYK
Chemical type: Peptide from protein
Sequence: IIQLVNAKHIPAYK
Position: 467-480
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 419 52

Epitope: IIQLVNAKHIPAYK
Chemical type: Peptide from protein
Sequence: IIQLVNAKHIPAYK
Position: 467-480
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 416 422

Epitope: TSRFARLQKLHT
Chemical type: Peptide from protein
Sequence: TSRFARLQKLHT
Position: 625-636
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 416 422

Epitope: DAMGMNMISKGTEK
Chemical type: Peptide from protein
Sequence: DAMGMNMISKGTEK
Position: 653-666
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 416 422

Epitope: DAMGMNMISKGTEK
Chemical type: Peptide from protein
Sequence: DAMGMNMISKGTEK
Position: 653-666
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: DAMGMNMISKGTEK
Chemical type: Peptide from protein
Sequence: DAMGMNMISKGTEK
Position: 653-666
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 425

Epitope: DAMGMNMISKGTEKA
Chemical type: Peptide from protein
Sequence: DAMGMNMISKGTEKA
Position: 653-667
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: DAMGMNMISKGTEKAL
Chemical type: Peptide from protein
Sequence: DAMGMNMISKGTEKAL
Position: 653-668
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: AMGMNMISKGTEK
Chemical type: Peptide from protein
Sequence: AMGMNMISKGTEK
Position: 654-666
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 425

Epitope: AMGMNMISKGTEK
Chemical type: Peptide from protein
Sequence: AMGMNMISKGTEK
Position: 654-666
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: AMGMNMISKGTEKA
Chemical type: Peptide from protein
Sequence: AMGMNMISKGTEKA
Position: 654-667
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: ISKGTEKALSKLHE
Chemical type: Peptide from protein
Sequence: ISKGTEKALSKLHE
Position: 660-673
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 416 422

Epitope: SIGGYNAHAANIVT
Chemical type: Peptide from protein
Sequence: SIGGYNAHAANIVT
Position: 745-758
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 419 413

Epitope: SIGGYNAHAANIVT
Chemical type: Peptide from protein
Sequence: SIGGYNAHAANIVT
Position: 745-758
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: SIGGYNAHAANIVT
Chemical type: Peptide from protein
Sequence: SIGGYNAHAANIVT
Position: 745-758
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 436 422

Epitope: SIGGYNAHAANIVTA
Chemical type: Peptide from protein
Sequence: SIGGYNAHAANIVTA
Position: 745-759
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 419 413

Epitope: SIGGYNAHAANIVTA
Chemical type: Peptide from protein
Sequence: SIGGYNAHAANIVTA
Position: 745-759
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 436 422

Epitope: SIGGYNAHAANIVTA
Chemical type: Peptide from protein
Sequence: SIGGYNAHAANIVTA
Position: 745-759
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: IGGYNAHAANIVT
Chemical type: Peptide from protein
Sequence: IGGYNAHAANIVT
Position: 746-758
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: IGGYNAHAANIVT
Chemical type: Peptide from protein
Sequence: IGGYNAHAANIVT
Position: 746-758
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 419 413

Epitope: IGGYNAHAANIVT
Chemical type: Peptide from protein
Sequence: IGGYNAHAANIVT
Position: 746-758
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 436 422

Epitope: IGGYNAHAANIVTA
Chemical type: Peptide from protein
Sequence: IGGYNAHAANIVTA
Position: 746-759
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 419 413

Epitope: IGGYNAHAANIVTA
Chemical type: Peptide from protein
Sequence: IGGYNAHAANIVTA
Position: 746-759
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 414 413

Epitope: GGYNAHAANIVT
Chemical type: Peptide from protein
Sequence: GGYNAHAANIVT
Position: 747-758
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 419 413

Epitope: GGYNAHAANIVT
Chemical type: Peptide from protein
Sequence: GGYNAHAANIVT
Position: 747-758
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 436 422

Epitope: GGYNAHAANIVTA
Chemical type: Peptide from protein
Sequence: GGYNAHAANIVTA
Position: 747-759
Source molecule (GenBank): P04035.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 419 413