Reference: Andréa Toma; Taghrid Laïka; Samy Haddouk; Sandrine Luce; Jean-Paul Briand; Luc Camoin; Francine Connan; Marion Lambert; Sophie Caillat-Zucman; Jean-Claude Carel; Sylviane Muller; Jeannine Choppin; François Lemonnier; Christian Boitard. "Recognition of human proinsulin leader sequence by class I-restricted T-cells in HLA-A*0201 transgenic mice and in human type 1 diabetes." Diabetes (2009).

Epitope: Preproinsulin 2-11
Chemical type: Peptide from protein
Sequence: ALWMRLLPLL
Position: 2-11
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 2-11
Chemical type: Peptide from protein
Sequence: ALWMRLLPLL
Position: 2-11
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 2-11
Chemical type: Peptide from protein
Sequence: ALWMRLLPLL
Position: 2-11
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 2-11
Chemical type: Peptide from protein
Sequence: ALWMRLLPLL
Position: 2-11
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 2-11
Chemical type: Peptide from protein
Sequence: ALWMRLLPLL
Position: 2-11
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 2-11
Chemical type: Peptide from protein
Sequence: ALWMRLLPLL
Position: 2-11
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 2-11
Chemical type: Peptide from protein
Sequence: ALWMRLLPLL
Position: 2-11
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 2-11
Chemical type: Peptide from protein
Sequence: ALWMRLLPLL
Position: 2-11
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 2-11
Chemical type: Peptide from protein
Sequence: ALWMRLLPLL
Position: 2-11
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: Preproinsulin 2-11
Chemical type: Peptide from protein
Sequence: ALWMRLLPLL
Position: 2-11
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 2-11
Chemical type: Peptide from protein
Sequence: ALWMRLLPLL
Position: 2-11
Source molecule (GenBank): ABI63346.1
Assay category: MhcBinding
Result: Positive-High

Epitope: Preproinsulin 2-11
Chemical type: Peptide from protein
Sequence: ALWMRLLPLL
Position: 2-11
Source molecule (GenBank): ABI63346.1
Assay category: MhcBinding
Result: Positive-High

Epitope: Preproinsulin 2-11
Chemical type: Peptide from protein
Sequence: ALWMRLLPLL
Position: 2-11
Source molecule (GenBank): ABI63346.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Preproinsulin 14-23
Chemical type: Peptide from protein
Sequence: LALWGPDPAA
Position: 14-23
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 14-23
Chemical type: Peptide from protein
Sequence: LALWGPDPAA
Position: 14-23
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 14-23
Chemical type: Peptide from protein
Sequence: LALWGPDPAA
Position: 14-23
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 14-23
Chemical type: Peptide from protein
Sequence: LALWGPDPAA
Position: 14-23
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: Preproinsulin 14-23
Chemical type: Peptide from protein
Sequence: LALWGPDPAA
Position: 14-23
Source molecule (GenBank): ABI63346.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Preproinsulin 15-24
Chemical type: Peptide from protein
Sequence: ALWGPDPAAA
Position: 15-24
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 15-24
Chemical type: Peptide from protein
Sequence: ALWGPDPAAA
Position: 15-24
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 15-24
Chemical type: Peptide from protein
Sequence: ALWGPDPAAA
Position: 15-24
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 15-24
Chemical type: Peptide from protein
Sequence: ALWGPDPAAA
Position: 15-24
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: Preproinsulin 15-24
Chemical type: Peptide from protein
Sequence: ALWGPDPAAA
Position: 15-24
Source molecule (GenBank): ABI63346.1
Assay category: MhcBinding
Result: Positive-High

Epitope: Preproinsulin 15-25
Chemical type: Peptide from protein
Sequence: ALWGPDPAAAF
Position: 15-25
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 15-25
Chemical type: Peptide from protein
Sequence: ALWGPDPAAAF
Position: 15-25
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 15-25
Chemical type: Peptide from protein
Sequence: ALWGPDPAAAF
Position: 15-25
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 15-25
Chemical type: Peptide from protein
Sequence: ALWGPDPAAAF
Position: 15-25
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 15-25
Chemical type: Peptide from protein
Sequence: ALWGPDPAAAF
Position: 15-25
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 15-25
Chemical type: Peptide from protein
Sequence: ALWGPDPAAAF
Position: 15-25
Source molecule (GenBank): ABI63346.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Preproinsulin 15-25
Chemical type: Peptide from protein
Sequence: ALWGPDPAAAF
Position: 15-25
Source molecule (GenBank): ABI63346.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Preproinsulin 15-25
Chemical type: Peptide from protein
Sequence: ALWGPDPAAAF
Position: 15-25
Source molecule (GenBank): ABI63346.1
Assay category: MhcBinding
Result: Positive-High

Epitope: M0 58-66
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): ABL61489.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M0 58-66
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): ABL61489.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NP 44-52
Chemical type: Peptide from protein
Sequence: CTELKLSDY
Position: 44-52
Source molecule (GenBank): ABG88425.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NP 44-52
Chemical type: Peptide from protein
Sequence: CTELKLSDY
Position: 44-52
Source molecule (GenBank): ABG88425.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NP 380-388
Chemical type: Peptide from protein
Sequence: ELRSRYWAI
Position: 380-388
Source molecule (GenBank): ABI36003.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NP 380-388
Chemical type: Peptide from protein
Sequence: ELRSRYWAI
Position: 380-388
Source molecule (GenBank): ABI36003.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Nef 83-91
Chemical type: Peptide from protein
Sequence: AAVDLSHFL
Position: 83-91
Source molecule (GenBank): ACR27130.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Nef 83-91
Chemical type: Peptide from protein
Sequence: AAVDLSHFL
Position: 83-91
Source molecule (GenBank): ACR27130.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Nef 182-189
Chemical type: Peptide from protein
Sequence: EWRFDSRLA
Position: 182-190
Source molecule (GenBank): P04324.3
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Nef 182-189
Chemical type: Peptide from protein
Sequence: EWRFDSRLA
Position: 182-190
Source molecule (GenBank): P04324.3
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo