Reference: Weijun Zhou; Jinyi Yu; Fuyu Li; Yuting Huang; Jingwen Du; Anqin Wu; Kankan Wang. "Identification of specific T-cell response and T-cell receptor targeting shared neoantigen for acute myeloid leukemia." Blood cancer journal (2025).

Epitope: NPM1 W288fs
Chemical type: Neo-epitope
Sequence: AIQDLCLAV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NPM1 W288fs
Chemical type: Neo-epitope
Sequence: AIQDLCLAV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NPM1 W288fs
Chemical type: Neo-epitope
Sequence: AIQDLCLAV
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NPM1 W288fs
Chemical type: Neo-epitope
Sequence: AIQDLCLAV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NPM1 W288fs
Chemical type: Neo-epitope
Sequence: AIQDLCLAV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NPM1 W288fs
Chemical type: Neo-epitope
Sequence: AIQDLCLAV
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: NPM1 W288fs
Chemical type: Neo-epitope
Sequence: AIQDLCLAV
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: NPM1 W288fs
Chemical type: Neo-epitope
Sequence: AIQDLCLAV
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: NPM1 W288fs
Chemical type: Neo-epitope
Sequence: AIQDLCLAV
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: NPM1 W288fs
Chemical type: Neo-epitope
Sequence: AIQDLCLAV
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: NPM1 W288fs
Chemical type: Neo-epitope
Sequence: AIQDLCLAV
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: NPM1 W288fs
Chemical type: Neo-epitope
Sequence: AIQDLCLAV
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: NPM1 W288fs
Chemical type: Neo-epitope
Sequence: AIQDLCLAV
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: NPM1 W288fs
Chemical type: Neo-epitope
Sequence: AIQDLCLAV
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: NPM1 W288fs
Chemical type: Neo-epitope
Sequence: AIQDLCLAV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 439.8

Epitope: NPM1 W288fs
Chemical type: Neo-epitope
Sequence: AIQDLCLAV
Assay category: MhcBinding
Result: Positive

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 451.2

Epitope: FLT3 D835H
Chemical type: Neo-epitope
Sequence: HIMSDSNYV
Assay category: MhcBinding
Result: Positive

Epitope: FLT3 D835Y
Chemical type: Neo-epitope
Sequence: YIMSDSNYV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: FLT3 D835Y
Chemical type: Neo-epitope
Sequence: YIMSDSNYV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: FLT3 D835Y
Chemical type: Neo-epitope
Sequence: YIMSDSNYV
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: FLT3 D835Y
Chemical type: Neo-epitope
Sequence: YIMSDSNYV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 454.2

Epitope: FLT3 D835Y
Chemical type: Neo-epitope
Sequence: YIMSDSNYV
Assay category: MhcBinding
Result: Positive

Epitope: DNMT3A R899H
Chemical type: Neo-epitope
Sequence: WSVPVIHHL
Assay category: MhcBinding
Result: Negative

Epitope: FLT3 N676K
Chemical type: Neo-epitope
Sequence: QLGSHENIVKL
Assay category: MhcBinding
Result: Negative

Epitope: TP53 G266V
Chemical type: Neo-epitope
Sequence: LLVRNSFEV
Assay category: MhcBinding
Result: Positive-Low

Epitope: TP53 H193D
Chemical type: Neo-epitope
Sequence: GLAPPQDLI
Assay category: MhcBinding
Result: Positive

Epitope: TP53 H193D
Chemical type: Neo-epitope
Sequence: GLAPPQDLI
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 480.0