Reference: Nathali Kaushansky; Nicole Kerlero de Rosbo; Rina Zilkha-Falb; Reut Yosef-Hemo; Lydia Cohen; Avraham Ben-Nun. "'Multi-epitope-targeted' immune-specific therapy for a multiple sclerosis-like disease via engineered multi-epitope protein is superior to peptides." PloS one (2011).

Epitope: phOSP55-74
Chemical type: Peptide from protein
Sequence: DCVMATGLYHCKPLVDILIL
Position: 55-74
Source molecule (GenBank): NP_005593.2
Assay category: TCell
Result: Positive
Host: F 2-3 months
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: phMOBP55-77
Chemical type: Peptide from protein
Sequence: KEEDWICCACQKTRTSRRAKSPQ
Position: 56-78
Source molecule (GenBank): Q13875.2
Assay category: TCell
Result: Positive
Host: F 2-3 months

Epitope: phMOBP55-77
Chemical type: Peptide from protein
Sequence: KEEDWICCACQKTRTSRRAKSPQ
Position: 56-78
Source molecule (GenBank): Q13875.2
Assay category: TCell
Result: Positive
Host: F 2-3 months
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: phMOBP15-36
Chemical type: Peptide from protein
Sequence: QKYSEHFSIHCCPPFTFLNSKK
Position: 16-37
Source molecule (GenBank): BAA05660.1
Assay category: TCell
Result: Positive
Host: F 2-3 months

Epitope: phMOBP15-36
Chemical type: Peptide from protein
Sequence: QKYSEHFSIHCCPPFTFLNSKK
Position: 16-37
Source molecule (GenBank): BAA05660.1
Assay category: TCell
Result: Positive-High
Host: F 2-3 months
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: phMOG34-56
Chemical type: Peptide from protein
Sequence: GMEVGWYRPPFSRVVHLYRNGKD
Position: 33-55
Source molecule (GenBank): CAB89274.1
Assay category: TCell
Result: Positive
Host: F 2-3 months

Epitope: phMOG34-56
Chemical type: Peptide from protein
Sequence: GMEVGWYRPPFSRVVHLYRNGKD
Position: 33-55
Source molecule (GenBank): CAB89274.1
Assay category: TCell
Result: Positive-High
Host: F 2-3 months
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: phMOG34-56
Chemical type: Peptide from protein
Sequence: GMEVGWYRPPFSRVVHLYRNGKD
Position: 33-55
Source molecule (GenBank): CAB89274.1
Assay category: TCell
Result: Positive
Host: F 2-3 months

Epitope: phPLP178-191
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSK
Position: 176-189
Source molecule (GenBank): AAA60350.1
Assay category: TCell
Result: Positive
Host: F 2-3 months

Epitope: phPLP178-191
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSK
Position: 176-189
Source molecule (GenBank): AAA60350.1
Assay category: TCell
Result: Positive
Host: F 2-3 months
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: phPLP139-151
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKF
Position: 140-152
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Host: F 2-3 months
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: phPLP139-151
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKF
Position: 140-152
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Host: F 2-3 months
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: phPLP139-151
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKF
Position: 140-152
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Host: F 2-3 months
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: phPLP139-151
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKF
Position: 140-152
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Host: F 2-3 months
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: phPLP139-151
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKF
Position: 140-152
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Host: F 2-3 months
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: phPLP139-151
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKF
Position: 140-152
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: phPLP139-151
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKF
Position: 140-152
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: phPLP139-151
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKF
Position: 140-152
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Negative
Host: F 2-3 months
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: phPLP139-151
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKF
Position: 140-152
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Negative
Host: F 2-3 months

Epitope: phPLP139-151
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKF
Position: 140-152
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Host: F 2-3 months

Epitope: phPLP139-151
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKF
Position: 140-152
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Host: F 2-3 months

Epitope: phPLP139-151
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKF
Position: 140-152
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive
Host: F 2-3 months

Epitope: phPLP139-151
Chemical type: Peptide from protein
Sequence: HCLGKWLGHPDKF
Position: 140-152
Source molecule (GenBank): AAA59565.1
Assay category: TCell
Result: Positive-High
Host: F 2-3 months
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: phMBP89-104
Chemical type: Peptide from protein
Sequence: FFKNIVTPRTPPPSQG
Position: 90-105
Source molecule (GenBank): AAH08749.3
Assay category: TCell
Result: Positive
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: phMBP89-104
Chemical type: Peptide from protein
Sequence: FFKNIVTPRTPPPSQG
Position: 90-105
Source molecule (GenBank): AAH08749.3
Assay category: TCell
Result: Negative
Host: F 2-3 months

Epitope: phMBP89-104
Chemical type: Peptide from protein
Sequence: FFKNIVTPRTPPPSQG
Position: 90-105
Source molecule (GenBank): AAH08749.3
Assay category: TCell
Result: Positive
Host: F 2-3 months

Epitope: phOSP55-71
Chemical type: Peptide from protein
Sequence: DCVMATGLYHCKPLVDI
Position: 55-71
Source molecule (GenBank): NP_005593.2
Assay category: TCell
Result: Positive
Host: F 2-3 months
Cell type: splenocyte
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: phOSP55-80
Chemical type: Peptide from protein
Sequence: DCVMATGLYHCKPLVDILILPGYVQA
Position: 55-80
Source molecule (GenBank): NP_005593.2
Assay category: TCell
Result: Positive
Host: F 2-3 months