Reference: W M Kast; R M Brandt; J W Drijfhout; C J Melief. "Human leukocyte antigen-A2.1 restricted candidate cytotoxic T lymphocyte epitopes of human papillomavirus type 16 E6 and E7 proteins identified by using the processing-defective human cell line T2." Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy (1993).

Epitope: HPV16 E6 peak 1
Chemical type: Peptide from protein
Sequence: KLPQLCTEL
Position: 18-26
Source molecule (GenBank): P03126
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 12000.0

Epitope: HPV16 E6 peak 2
Chemical type: Peptide from protein
Sequence: QLCTELQTT
Position: 21-29
Source molecule (GenBank): P03126
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 25000.0

Epitope: HPV16 E6 peak 3
Chemical type: Peptide from protein
Sequence: LCTELQTTI
Position: 22-30
Source molecule (GenBank): P03126
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: HPV16 E6 peak 4
Chemical type: Peptide from protein
Sequence: ELQTTIHDI
Position: 25-33
Source molecule (GenBank): P03126
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 200000.0

Epitope: HPV16 E6 peak 5
Chemical type: Peptide from protein
Sequence: LQTTIHDII
Position: 26-34
Source molecule (GenBank): P03126
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 25000.0

Epitope: HPV16 E6 peak 6
Chemical type: Peptide from protein
Sequence: TIHDIILEC
Position: 29-37
Source molecule (GenBank): P03126
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 50000.0

Epitope: HPV16 E6 peak 7
Chemical type: Peptide from protein
Sequence: IHDIILECV
Position: 30-38
Source molecule (GenBank): P03126
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 50000.0

Epitope: HPV16 E6 peak 8
Chemical type: Peptide from protein
Sequence: CVYCKQQLL
Position: 37-45
Source molecule (GenBank): P03126
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: HPV16 E6 peak 9
Chemical type: Peptide from protein
Sequence: KISEYRHYC
Position: 79-87
Source molecule (GenBank): P03126
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 125000.0

Epitope: HPV16 E6 peak 10
Chemical type: Peptide from protein
Sequence: PLCDLLIRC
Position: 102-110
Source molecule (GenBank): P03126
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 150000.0

Epitope: HPV16 E7 peak 12
Chemical type: Peptide from protein
Sequence: YMLDLQPET
Position: 11-19
Source molecule (GenBank): P03129
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 15000.0

Epitope: HPV16 E7 peak 13
Chemical type: Peptide from protein
Sequence: MLDLQPETT
Position: 12-20
Source molecule (GenBank): P03129
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HPV16 E7 peak 13
Chemical type: Peptide from protein
Sequence: MLDLQPETT
Position: 12-20
Source molecule (GenBank): P03129
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 15000.0

Epitope: HPV16 E7 peak 14
Chemical type: Peptide from protein
Sequence: RLCVQSTHV
Position: 66-74
Source molecule (GenBank): P03129
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 75000.0

Epitope: HPV16 E7 peak 15
Chemical type: Peptide from protein
Sequence: TLEDLLMGT
Position: 78-86
Source molecule (GenBank): P03129
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 62000.0

Epitope: HPV16 E7 peak 16
Chemical type: Peptide from protein
Sequence: LLMGTLGIV
Position: 82-90
Source molecule (GenBank): P03129
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 50000.0

Epitope: HPV16 E7 peak 17
Chemical type: Peptide from protein
Sequence: GTLGIVCPI
Position: 85-93
Source molecule (GenBank): P03129
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 200.0

Epitope: HPV16 E7 peak 18
Chemical type: Peptide from protein
Sequence: TLGIVCPIC
Position: 86-94
Source molecule (GenBank): P03129
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 12000.0