Reference: Chun-Yu Wei; Wen-Hung Chung; Hsiao-Wen Huang; Yuan-Tsong Chen; Shuen-Iu Hung. "Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome." The Journal of allergy and clinical immunology (2012).

Epitope: pp1
Chemical type: Peptide from protein
Sequence: ELWKNPTAF
Position: 154-162
Source molecule (GenBank): O00762.1
Assay category: TCell
Result: Positive
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: pp1
Chemical type: Peptide from protein
Sequence: ELWKNPTAF
Position: 154-162
Source molecule (GenBank): O00762.1
Assay category: MhcBinding
Result: Positive

Epitope: pp3
Chemical type: Peptide from protein
Sequence: NVIRDAVTY
Position: 65-73
Source molecule (GenBank): P02304
Assay category: TCell
Result: Positive
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: pp3
Chemical type: Peptide from protein
Sequence: NVIRDAVTY
Position: 65-73
Source molecule (GenBank): P02304
Assay category: MhcBinding
Result: Positive

Epitope: pp5
Chemical type: Peptide from protein
Sequence: FLFDGSPTY
Position: 2335-2343
Source molecule (GenBank): P49327.3
Assay category: TCell
Result: Positive
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: pp5
Chemical type: Peptide from protein
Sequence: FLFDGSPTY
Position: 2335-2343
Source molecule (GenBank): P49327.3
Assay category: MhcBinding
Result: Positive

Epitope: pp6
Chemical type: Peptide from protein
Sequence: SQFGGGSQY
Position: 61-69
Source molecule (GenBank): O15371.1
Assay category: TCell
Result: Positive
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: pp6
Chemical type: Peptide from protein
Sequence: SQFGGGSQY
Position: 61-69
Source molecule (GenBank): O15371.1
Assay category: MhcBinding
Result: Positive

Epitope: pp8
Chemical type: Peptide from protein
Sequence: FPYGTTVTY
Position: 546-554
Source molecule (GenBank): AAA35786.1
Assay category: TCell
Result: Positive
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: pp8
Chemical type: Peptide from protein
Sequence: FPYGTTVTY
Position: 546-554
Source molecule (GenBank): AAA35786.1
Assay category: MhcBinding
Result: Positive

Epitope: pp9
Chemical type: Peptide from protein
Sequence: YMIDPSGVSY
Position: 150-159
Source molecule (GenBank): P25788.2
Assay category: TCell
Result: Positive
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: pp9
Chemical type: Peptide from protein
Sequence: YMIDPSGVSY
Position: 150-159
Source molecule (GenBank): P25788.2
Assay category: MhcBinding
Result: Positive

Epitope: pp10
Chemical type: Peptide from protein
Sequence: EQYEQILAF
Position: 202-210
Source molecule (GenBank): P41091.3
Assay category: TCell
Result: Positive
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: pp10
Chemical type: Peptide from protein
Sequence: EQYEQILAF
Position: 202-210
Source molecule (GenBank): P41091.3
Assay category: MhcBinding
Result: Positive

Epitope: pp12
Chemical type: Peptide, no natural source
Sequence: TILDSSSSF
Assay category: TCell
Result: Positive
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: pp12
Chemical type: Peptide, no natural source
Sequence: TILDSSSSF
Assay category: MhcBinding
Result: Positive

Epitope: np1
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 47-56
Source molecule (GenBank): AAK51536.1
Assay category: TCell
Result: Negative
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: np1
Chemical type: Peptide from protein
Sequence: FLPSDFFPSV
Position: 47-56
Source molecule (GenBank): AAK51536.1
Assay category: MhcBinding
Result: Negative

Epitope: np2
Chemical type: Peptide from protein
Sequence: FVPPPPPPP
Position: 45-53
Source molecule (GenBank): P02814.2
Assay category: TCell
Result: Negative
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: np2
Chemical type: Peptide from protein
Sequence: FVPPPPPPP
Position: 45-53
Source molecule (GenBank): P02814.2
Assay category: MhcBinding
Result: Negative

Epitope: np3
Chemical type: Peptide from protein
Sequence: APPPPPPPP
Position: 59-67
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Negative
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: np3
Chemical type: Peptide from protein
Sequence: APPPPPPPP
Position: 59-67
Source molecule (GenBank): P19544.2
Assay category: MhcBinding
Result: Negative

Epitope: np4
Chemical type: Peptide from protein
Sequence: APPPPPPGH
Position: 752-760
Source molecule (GenBank): AAN45858.1
Assay category: TCell
Result: Negative
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: np4
Chemical type: Peptide from protein
Sequence: APPPPPPGH
Position: 752-760
Source molecule (GenBank): AAN45858.1
Assay category: MhcBinding
Result: Negative

Epitope: carbamazepine (CBZ)
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: carbamazepine (CBZ)
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: carbamazepine (CBZ)
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: carbamazepine (CBZ)
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: carbamazepine (CBZ)
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: carbamazepine (CBZ)
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive

Epitope: carbamazepine (CBZ)
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Negative

Epitope: carbamazepine (CBZ)
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Negative

Epitope: carbamazepine (CBZ)
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Negative

Epitope: carbamazepine (CBZ)
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Negative

Epitope: carbamazepine 10,11-epoxide (ECBZ)
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: carbamazepine 10,11-epoxide (ECBZ)
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive

Epitope: carbamazepine 10,11-epoxide (ECBZ)
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Negative

Epitope: carbamazepine 10,11-epoxide (ECBZ)
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Negative

Epitope: carbamazepine 10,11-epoxide (ECBZ)
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Negative

Epitope: carbamazepine 10,11-epoxide (ECBZ)
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Negative

Epitope: oxcarbazepine (OXC)
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: oxcarbazepine (OXC)
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive

Epitope: licarbazepine (LIC)
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive-Low
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: licarbazepine (LIC)
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive-Low

Epitope: 5H-dibenzazepine (5HB; iminostilbbene)
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Negative
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: 5H-dibenzazepine (5HB; iminostilbbene)
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Negative

Epitope: eslicarbazepine acetate (ESL)
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Host:  11-80 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: eslicarbazepine acetate (ESL)
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive