Reference: Amanda Atanasio; Matthew C Franklin; Vishal Kamat; Annabel Romero Hernandez; Ashok Badithe; Li-Hong Ben; Jennifer Jones; Joannie Bautista; George D Yancopoulos; William Olson; Andrew J Murphy; Matthew A Sleeman; Jamie M Orengo. "Targeting immunodominant Bet v 1 epitopes with monoclonal antibodies prevents the birch allergic response." The Journal of allergy and clinical immunology (2022).

Epitope: Epitope of REGN5713 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: T11, S12, V13, P32, K33, V34, P36, Q37, E142, T143, R146, A147, E149, S150, Y151, L153, A154, H155
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 1.29

Epitope: Epitope of REGN5713 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: T11, S12, V13, P32, K33, V34, P36, Q37, E142, T143, R146, A147, E149, S150, Y151, L153, A154, H155
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 281000.0

Epitope: Epitope of REGN5713 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: T11, S12, V13, P32, K33, V34, P36, Q37, E142, T143, R146, A147, E149, S150, Y151, L153, A154, H155
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000337

Epitope: Epitope of REGN5713 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: T11, S12, V13, P32, K33, V34, P36, Q37, E142, T143, R146, A147, E149, S150, Y151, L153, A154, H155
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 697000.0

Epitope: Epitope of REGN5713 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: T11, S12, V13, P32, K33, V34, P36, Q37, E142, T143, R146, A147, E149, S150, Y151, L153, A154, H155
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000331

Epitope: Epitope of REGN5713 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: T11, S12, V13, P32, K33, V34, P36, Q37, E142, T143, R146, A147, E149, S150, Y151, L153, A154, H155
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 1400000.0

Epitope: Epitope of REGN5713 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: T11, S12, V13, P32, K33, V34, P36, Q37, E142, T143, R146, A147, E149, S150, Y151, L153, A154, H155
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000861

Epitope: Epitope of REGN5713 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: T11, S12, V13, P32, K33, V34, P36, Q37, E142, T143, R146, A147, E149, S150, Y151, L153, A154, H155
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Negative

Epitope: Epitope of REGN5713 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: T11, S12, V13, P32, K33, V34, P36, Q37, E142, T143, R146, A147, E149, S150, Y151, L153, A154, H155
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.475

Epitope: Epitope of REGN5713 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: T11, S12, V13, P32, K33, V34, P36, Q37, E142, T143, R146, A147, E149, S150, Y151, L153, A154, H155
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.617

Epitope: Epitope of REGN5713 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: T11, S12, V13, P32, K33, V34, P36, Q37, E142, T143, R146, A147, E149, S150, Y151, L153, A154, H155
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive

Epitope: Epitope of REGN5713 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: T11, S12, V13, P32, K33, V34, P36, Q37, E142, T143, R146, A147, E149, S150, Y151, L153, A154, H155
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 3.0

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0418

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 1250000.0

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0374

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 396.0

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 106000.0

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 29.8

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 1.03

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 312000.0

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000323

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00124

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 90.5

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 390000.0

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0353

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2180000.0

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 951000.0

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00172

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.567

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Negative

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 1.81

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive

Epitope: Epitope of REGN5715 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: E43, N44, I45, E46, G47, N48, G49, G50, P51, V75
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 3.71

Epitope: Epitope of REGN5714 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: G2, V3, N5, E7, R71, D73, E74, N79, K81, N83, Y84, S85, E97, K98, S100, E102, K104, K116, S118, K120, H122, T123
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 41.4

Epitope: Epitope of REGN5714 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: G2, V3, N5, E7, R71, D73, E74, N79, K81, N83, Y84, S85, E97, K98, S100, E102, K104, K116, S118, K120, H122, T123
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 151000.0

Epitope: Epitope of REGN5714 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: G2, V3, N5, E7, R71, D73, E74, N79, K81, N83, Y84, S85, E97, K98, S100, E102, K104, K116, S118, K120, H122, T123
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00623

Epitope: Epitope of REGN5714 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: G2, V3, N5, E7, R71, D73, E74, N79, K81, N83, Y84, S85, E97, K98, S100, E102, K104, K116, S118, K120, H122, T123
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 3.24

Epitope: Epitope of REGN5714 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: G2, V3, N5, E7, R71, D73, E74, N79, K81, N83, Y84, S85, E97, K98, S100, E102, K104, K116, S118, K120, H122, T123
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Negative

Epitope: Epitope of REGN5714 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: G2, V3, N5, E7, R71, D73, E74, N79, K81, N83, Y84, S85, E97, K98, S100, E102, K104, K116, S118, K120, H122, T123
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 50.5

Epitope: Epitope of REGN5714 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: G2, V3, N5, E7, R71, D73, E74, N79, K81, N83, Y84, S85, E97, K98, S100, E102, K104, K116, S118, K120, H122, T123
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 490000.0

Epitope: Epitope of REGN5714 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: G2, V3, N5, E7, R71, D73, E74, N79, K81, N83, Y84, S85, E97, K98, S100, E102, K104, K116, S118, K120, H122, T123
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00159

Epitope: Epitope of REGN5714 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: G2, V3, N5, E7, R71, D73, E74, N79, K81, N83, Y84, S85, E97, K98, S100, E102, K104, K116, S118, K120, H122, T123
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 128000.0

Epitope: Epitope of REGN5714 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: G2, V3, N5, E7, R71, D73, E74, N79, K81, N83, Y84, S85, E97, K98, S100, E102, K104, K116, S118, K120, H122, T123
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00648

Epitope: Epitope of REGN5714 on Bet v 1
Chemical type: Discontinuous protein residues
Discontinuous residues: G2, V3, N5, E7, R71, D73, E74, N79, K81, N83, Y84, S85, E97, K98, S100, E102, K104, K116, S118, K120, H122, T123
Source molecule (GenBank): P15494.2
Assay category: BCell
Result: Positive