Reference: Eun Joo Chung; Soyoung Park; Su-Hwan Kim; Ju-Yeon Choi; Hye-Sook Jeong; Jae-Hoon Ko; Joon Young Song; Young Jae Lee. "Impaired and restored CD8<sup>+</sup> T cell responses to a sequentially mutated spike epitope in Omicron variants." Frontiers in immunology (2025).

Epitope: LYN
Chemical type: Peptide from protein
Sequence: LYNSASFSTF
Position: 368-377
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: LYN
Chemical type: Peptide from protein
Sequence: LYNSASFSTF
Position: 368-377
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: LYN
Chemical type: Peptide from protein
Sequence: LYNSASFSTF
Position: 368-377
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: VYF
Chemical type: Peptide from protein
Sequence: VYFASTEKSNI
Position: 90-100
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: VYF
Chemical type: Peptide from protein
Sequence: VYFASTEKSNI
Position: 90-100
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: TQL
Chemical type: Peptide from protein
Sequence: TQLPPAYTNSF
Position: 22-32
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: TQL
Chemical type: Peptide from protein
Sequence: TQLPPAYTNSF
Position: 22-32
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: LYN S371L
Chemical type: Peptide from protein
Sequence: LYNLASFSTF
Position: 370-379
Source molecule (GenBank): UKT98745.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: LYN S371L
Chemical type: Peptide from protein
Sequence: LYNLASFSTF
Position: 370-379
Source molecule (GenBank): UKT98745.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: LYN S371F
Chemical type: Peptide from protein
Sequence: LYNFASFSTF
Position: 368-377
Source molecule (GenBank): WMQ66000.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: LYN S371F
Chemical type: Peptide from protein
Sequence: LYNFASFSTF
Position: 368-377
Source molecule (GenBank): WMQ66000.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: LYN S737P
Chemical type: Peptide from protein
Sequence: LYNSAPFSTF
Position: 370-379
Source molecule (GenBank): UMW82408.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: LYN S737P
Chemical type: Peptide from protein
Sequence: LYNSAPFSTF
Position: 370-379
Source molecule (GenBank): UMW82408.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: LYN S375F
Chemical type: Peptide from protein
Sequence: LYNSASFFTF
Position: 370-379
Source molecule (GenBank): ULV02921.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: LYN S375F
Chemical type: Peptide from protein
Sequence: LYNSASFFTF
Position: 370-379
Source molecule (GenBank): ULV02921.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: LYN T376A
Chemical type: Peptide from protein
Sequence: LYNSASFSAF
Position: 366-375
Source molecule (GenBank): UDJ78645.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: LYN T376A
Chemical type: Peptide from protein
Sequence: LYNSASFSAF
Position: 366-375
Source molecule (GenBank): UDJ78645.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: BA.1
Chemical type: Peptide from protein
Sequence: LYNSASFSTF
Position: 370-379
Source molecule (GenBank): UKF78016.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation

Epitope: BA.2
Chemical type: Peptide from protein
Sequence: LYNLAPFFAF
Position: 368-377
Source molecule (GenBank): WJJ65347.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Non-antigen specific activation