Reference: Jia Jia Lim; Claerwen M Jones; Tiing Jen Loh; Yi Tian Ting; Pirooz Zareie; Khai L Loh; Nathan J Felix; Anish Suri; Murray McKinnon; Frederik Stevenaert; Ravi K Sharma; Lars Klareskog; Vivianne Malmström; Daniel G Baker; Anthony W Purcell; Hugh H Reid; Nicole L La Gruta; Jamie Rossjohn. "The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR." Science immunology (2021).

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Host:  10-18 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 12500.0

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 2.35

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 2.75

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 127700.0

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 9700.0
Host:  10-18 weeks

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 18600.0
Host:  10-18 weeks

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 9300.0
Host:  10-18 weeks

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 2.29
Host:  10-18 weeks

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Cell type: HEK293 cell (epithelial cell)
Tissue: kidney
Culture conditions: Engineered

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Cell type: HEK293 cell (epithelial cell)
Tissue: kidney
Culture conditions: Engineered

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 156400.0

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 81300.0

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive-Low
Cell type: HEK293 cell (epithelial cell)
Tissue: kidney
Culture conditions: Engineered

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 4700.0
Host:  10-18 weeks

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 27700.0
Host:  10-18 weeks

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Cell type: HEK293 cell (epithelial cell)
Tissue: kidney
Culture conditions: Engineered

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Host:  10-18 weeks
Cell type: HEK293 cell (epithelial cell)
Tissue: kidney
Culture conditions: Engineered

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Host:  10-18 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Cell type: HEK293 cell (epithelial cell)
Tissue: kidney
Culture conditions: Engineered

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 8500.0
Host:  10-18 weeks

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Cell type: HEK293 cell (epithelial cell)
Tissue: kidney
Culture conditions: Engineered

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Host:  10-18 weeks
Cell type: HEK293 cell (epithelial cell)
Tissue: kidney
Culture conditions: Engineered

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Host:  10-18 weeks
Cell type: HEK293 cell (epithelial cell)
Tissue: kidney
Culture conditions: Engineered

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.75

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.29

Epitope: Fibß 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.35

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 22300.0
Host:  10-18 weeks

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 155700.0
Host:  10-18 weeks

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 60800.0
Host:  10-18 weeks

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 13400.0
Host:  10-18 weeks

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Host:  10-18 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 654900.0

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 51400.0

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 104900.0

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 101900.0

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 2.6
Host:  10-18 weeks

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 2.7

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Quantitative measurement: 2.8

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Cell type: HEK293 cell (epithelial cell)
Tissue: kidney
Culture conditions: Engineered

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Host:  10-18 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Host:  10-18 weeks
Cell type: HEK293 cell (epithelial cell)
Tissue: kidney
Culture conditions: Engineered

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Host:  10-18 weeks
Cell type: HEK293 cell (epithelial cell)
Tissue: kidney
Culture conditions: Engineered

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: TCell
Result: Positive
Cell type: HEK293 cell (epithelial cell)
Tissue: kidney
Culture conditions: Engineered

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.6

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.7

Epitope: Fibß 72, 74-cit (69-81)
Chemical type: Peptide from protein
Sequence: GGYRARPAKAAAT
Position: 69-81
Source molecule (GenBank): P02675.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.8