Reference: Pavel Pichurin; Lise Schwarz-Lauer; Helen Braley-Mullen; Charmaine Paras; Oxana Pichurina; John C Morris; Basil Rapoport; Sandra M McLachlan. "Peptide scanning for thyrotropin receptor T-cell epitopes in mice vaccinated with naked DNA." Thyroid : official journal of the American Thyroid Association (2002).

Epitope: A
Chemical type: Peptide from protein
Sequence: MGCSSPPCECHQEEDFRVTC
Position: 22-41
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: A
Chemical type: Peptide from protein
Sequence: MGCSSPPCECHQEEDFRVTC
Position: 22-41
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: B
Chemical type: Peptide from protein
Sequence: FRVTCKDIQRIPSLPPSTQT
Position: 37-56
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: B
Chemical type: Peptide from protein
Sequence: FRVTCKDIQRIPSLPPSTQT
Position: 37-56
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C
Chemical type: Peptide from protein
Sequence: PSTQTLKLIETHLRTIPSHA
Position: 52-71
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C
Chemical type: Peptide from protein
Sequence: PSTQTLKLIETHLRTIPSHA
Position: 52-71
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive-High
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: D
Chemical type: Peptide from protein
Sequence: IPSHAFSNLPNISRIYVSID
Position: 67-86
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: D
Chemical type: Peptide from protein
Sequence: IPSHAFSNLPNISRIYVSID
Position: 67-86
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive-Low
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: E
Chemical type: Peptide from protein
Sequence: YVSIDVTLQQLESHSFYNLS
Position: 82-101
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: E
Chemical type: Peptide from protein
Sequence: YVSIDVTLQQLESHSFYNLS
Position: 82-101
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: G
Chemical type: Peptide from protein
Sequence: RNLTYIDPDALKELPLLKFL
Position: 112-131
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: G
Chemical type: Peptide from protein
Sequence: RNLTYIDPDALKELPLLKFL
Position: 112-131
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H
Chemical type: Peptide from protein
Sequence: LLKFLGIFNTGLKMFPDLTK
Position: 127-146
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: H
Chemical type: Peptide from protein
Sequence: LLKFLGIFNTGLKMFPDLTK
Position: 127-146
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: I
Chemical type: Peptide from protein
Sequence: PDLTKVYSTDIFFILEITDN
Position: 142-161
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: I
Chemical type: Peptide from protein
Sequence: PDLTKVYSTDIFFILEITDN
Position: 142-161
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: J
Chemical type: Peptide from protein
Sequence: EITDNPYMTSIPVNAFQGLC
Position: 157-176
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive-High
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: J
Chemical type: Peptide from protein
Sequence: EITDNPYMTSIPVNAFQGLC
Position: 157-176
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: K
Chemical type: Peptide from protein
Sequence: FQGLCNETLTLKLYNNGFTS
Position: 172-191
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: K
Chemical type: Peptide from protein
Sequence: FQGLCNETLTLKLYNNGFTS
Position: 172-191
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive-Low
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L
Chemical type: Peptide from protein
Sequence: NGFTSVQGYAFNGTKLDAVY
Position: 187-206
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L
Chemical type: Peptide from protein
Sequence: NGFTSVQGYAFNGTKLDAVY
Position: 187-206
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M
Chemical type: Peptide from protein
Sequence: LDAVYLNKNKYLTVIDKDAF
Position: 202-221
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M
Chemical type: Peptide from protein
Sequence: LDAVYLNKNKYLTVIDKDAF
Position: 202-221
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: N
Chemical type: Peptide from protein
Sequence: DKDAFGGVYSGPSLLDVSQT
Position: 217-236
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: N
Chemical type: Peptide from protein
Sequence: DKDAFGGVYSGPSLLDVSQT
Position: 217-236
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: O
Chemical type: Peptide from protein
Sequence: DVSQTSVTALPSKGLEHLKE
Position: 232-251
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: O
Chemical type: Peptide from protein
Sequence: DVSQTSVTALPSKGLEHLKE
Position: 232-251
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive-Low
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: P
Chemical type: Peptide from protein
Sequence: EHLKELIARNTWTLKKLPLS
Position: 247-266
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: P
Chemical type: Peptide from protein
Sequence: EHLKELIARNTWTLKKLPLS
Position: 247-266
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Q
Chemical type: Peptide from protein
Sequence: KLPLSLSFLHLTRADLSYPS
Position: 262-281
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Q
Chemical type: Peptide from protein
Sequence: KLPLSLSFLHLTRADLSYPS
Position: 262-281
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive-Low
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: R
Chemical type: Peptide from protein
Sequence: LSYPSHCCAFKNQKKIRGIL
Position: 277-296
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: R
Chemical type: Peptide from protein
Sequence: LSYPSHCCAFKNQKKIRGIL
Position: 277-296
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S
Chemical type: Peptide from protein
Sequence: IRGILESLMCNESSMQSLRQ
Position: 292-311
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S
Chemical type: Peptide from protein
Sequence: IRGILESLMCNESSMQSLRQ
Position: 292-311
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: T
Chemical type: Peptide from protein
Sequence: QSLRQRKSVNALNSPLHQEY
Position: 307-326
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: T
Chemical type: Peptide from protein
Sequence: QSLRQRKSVNALNSPLHQEY
Position: 307-326
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: U
Chemical type: Peptide from protein
Sequence: LHQEYEENLGDSIVGYKEKS
Position: 322-341
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: U
Chemical type: Peptide from protein
Sequence: LHQEYEENLGDSIVGYKEKS
Position: 322-341
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: V
Chemical type: Peptide from protein
Sequence: YKEKSKFQDTHNNAHYYVFF
Position: 337-356
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: V
Chemical type: Peptide from protein
Sequence: YKEKSKFQDTHNNAHYYVFF
Position: 337-356
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: X
Chemical type: Peptide from protein
Sequence: GQELKNPQEETLQAFDSHYD
Position: 367-386
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: X
Chemical type: Peptide from protein
Sequence: GQELKNPQEETLQAFDSHYD
Position: 367-386
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Y
Chemical type: Peptide from protein
Sequence: DSHYDYTICGDSEDMVCTPK
Position: 382-401
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Y
Chemical type: Peptide from protein
Sequence: DSHYDYTICGDSEDMVCTPK
Position: 382-401
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EC1
Chemical type: Peptide from protein
Sequence: DLYTHSEYYNHAIDWQTGPGC
Position: 474-494
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EC1
Chemical type: Peptide from protein
Sequence: DLYTHSEYYNHAIDWQTGPGC
Position: 474-494
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EC2
Chemical type: Peptide from protein
Sequence: SSYAKVSICLPMDTETPLAL
Position: 561-580
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EC2
Chemical type: Peptide from protein
Sequence: SSYAKVSICLPMDTETPLAL
Position: 561-580
Source molecule (GenBank): AAR07906.1
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EC3
Chemical type: Peptide from protein
Sequence: NKPLITVTNSKY
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: EC3
Chemical type: Peptide from protein
Sequence: NKPLITVTNSKY
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo