LiteFold/IEDB huggingface dataset:
Reference: Klaus Pechhold; Sagarika Chakrabarty; David M Harlan. "Cytotoxic T cell-mediated diabetes in RIP-CD80 transgenic mice: autoantigen peptide sensitivity and fine specificity." Annals of the New York Academy of Sciences (2007).

Epitope: Ins1<sub>3-10</sub>
Chemical type: Peptide from protein
Sequence: LLVHFLPL
Position: 3-10
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative

Epitope: Ins2<sub>3-10</sub>
Chemical type: Peptide from protein
Sequence: LWMRFLPL
Position: 3-10
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Negative

Epitope: Ins2B<sub>31-39</sub>
Chemical type: Peptide from protein
Sequence: CGSHLVEAL
Position: 31-39
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Negative

Epitope: Ins2B<sub>46-53</sub>
Chemical type: Peptide from protein
Sequence: RGFFYTPM
Position: 46-53
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Negative

Epitope: InsA<sub>101-110</sub>
Chemical type: Peptide from protein
Sequence: SLYQLENYCN
Position: 101-110
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Negative

Epitope: LCMV-GP (33-41)
Chemical type: Peptide, no natural source
Sequence: KAVYNFATM
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: LCMV-GP (33-41)
Chemical type: Peptide, no natural source
Sequence: KAVYNFATM
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: lymphoid
Culture conditions: Direct Ex Vivo

Epitope: LCMV-GP (33-41)
Chemical type: Peptide, no natural source
Sequence: KAVYNFATM
Assay category: TCell
Result: Positive
Reference: Sabine Sévère; Anne Gauvrit; Anh-Tuan Vu; Jean-Marie Bach. "CD8+ T lymphocytes specific for glutamic acid decarboxylase 90-98 epitope mediate diabetes in NOD SCID mouse." Molecular immunology (2007).

Epitope: Mouse GAD65 p436 (436-444)
Chemical type: Peptide from protein
Sequence: SYDTGDKAL
Position: 436-444
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Negative
Host: F 3 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Human GAD65 p507 (507-516)
Chemical type: Peptide from protein
Sequence: WYIPPSLRTL
Position: 507-516
Source molecule (GenBank): NP_000809.1
Assay category: TCell
Result: Negative
Host: F 3 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Mouse GAD65 p109 (109-117)
Chemical type: Peptide from protein
Sequence: AFLQDVMNI
Position: 109-117
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Negative
Host: F 3 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Mouse GAD65 p178 (178-186)
Chemical type: Peptide from protein
Sequence: YFNQLSTGL
Position: 178-186
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Negative
Host: F 3 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo
Reference: John A Gebe; Kellee A Unrath; Ben A Falk; Kouichi Ito; Li Wen; Terri L Daniels; Ake Lernmark; Gerald T Nepom. "Age-dependent loss of tolerance to an immunodominant epitope of glutamic acid decarboxylase in diabetic-prone RIP-B7/DR4 mice." Clinical immunology (Orlando, Fla.) (2006).

Epitope: GAD65 (555-567)
Chemical type: Peptide from protein
Sequence: NFFRMVISNPAAT
Position: 555-567
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive
Host:  >24 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: GAD65 (555-567)
Chemical type: Peptide from protein
Sequence: NFFRMVISNPAAT
Position: 555-567
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive-High
Host:  8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: GFAP (240-252)
Chemical type: Peptide from protein
Sequence: TQYEAVATSNMQE
Position: 237-249
Source molecule (GenBank): EDL34160.1
Assay category: TCell
Result: Positive
Host:  >24 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: GFAP (240-252)
Chemical type: Peptide from protein
Sequence: TQYEAVATSNMQE
Position: 237-249
Source molecule (GenBank): EDL34160.1
Assay category: TCell
Result: Positive-Low
Host:  8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: IGRP (247-258)
Chemical type: Peptide from protein
Sequence: DWIHIDSTPFAG
Position: 247-258
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Negative
Host:  8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: IGRP (247-258)
Chemical type: Peptide from protein
Sequence: DWIHIDSTPFAG
Position: 247-258
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Negative
Host:  >24 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: IGRP (247-258)
Chemical type: Peptide from protein
Sequence: DWIHIDSTPFAG
Position: 247-258
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo
Reference: Gustavo Fenalti; Christiane S Hampe; Karen O'connor; J Paul Banga; Ian R Mackay; Merrill J Rowley; Ossama El-Kabbani. "Molecular characterization of a disease associated conformational epitope on GAD65 recognised by a human monoclonal antibody b96.11." Molecular immunology (2007).

Epitope: mAb b96.11-selected mimotope
Chemical type: Peptide, no natural source
Sequence: SILPYPY
Assay category: BCell
Result: Positive
Host: M 28 years

Epitope: mAb b96.11-selected mimotope
Chemical type: Peptide, no natural source
Sequence: YLTMPTP
Assay category: BCell
Result: Positive
Host: M 28 years

Epitope: mAb b96.11-selected mimotope
Chemical type: Peptide, no natural source
Sequence: TCHPVII
Assay category: BCell
Result: Positive
Host: M 28 years

Epitope: mAb b96.11-selected mimotope
Chemical type: Peptide, no natural source
Sequence: PANAHPQ
Assay category: BCell
Result: Positive
Host: M 28 years

Epitope: mAb b96.11-selected mimotope
Chemical type: Peptide, no natural source
Sequence: PTNAHPQ
Assay category: BCell
Result: Positive
Host: M 28 years

Epitope: mAb b96.11-selected mimotope
Chemical type: Peptide, no natural source
Sequence: SQNALPK
Assay category: BCell
Result: Positive
Host: M 28 years

Epitope: mAb b96.11-selected mimotope
Chemical type: Peptide, no natural source
Sequence: TRSQAAT
Assay category: BCell
Result: Positive
Host: M 28 years

Epitope: mAb b96.11-selected mimotope
Chemical type: Peptide, no natural source
Sequence: TTYQAAT
Assay category: BCell
Result: Positive
Host: M 28 years

Epitope: mAb b96.11-selected mimotope
Chemical type: Peptide, no natural source
Sequence: RPSTYPL
Assay category: BCell
Result: Positive
Host: M 28 years

Epitope: mAb b96.11-selected mimotope
Chemical type: Peptide, no natural source
Sequence: PATLTKK
Assay category: BCell
Result: Positive
Host: M 28 years

Epitope: mAb b96.11-selected mimotope
Chemical type: Peptide, no natural source
Sequence: SNYWLRS
Assay category: BCell
Result: Positive
Host: M 28 years

Epitope: mAb b96.11-selected mimotope
Chemical type: Peptide, no natural source
Sequence: PNFSWLR
Assay category: BCell
Result: Positive
Host: M 28 years

Epitope: mAb b96.11-selected mimotope
Chemical type: Peptide, no natural source
Sequence: ERYELRS
Assay category: BCell
Result: Positive
Host: M 28 years

Epitope: mAb b96.11-selected mimotope
Chemical type: Peptide, no natural source
Sequence: TYYNLRS
Assay category: BCell
Result: Positive
Host: M 28 years

Epitope: mAb b96.11-selected mimotope
Chemical type: Peptide, no natural source
Sequence: KHHYLRS
Assay category: BCell
Result: Positive
Host: M 28 years

Epitope: mAb b96.11-selected mimotope
Chemical type: Peptide, no natural source
Sequence: SPNHNSF
Assay category: BCell
Result: Positive
Host: M 28 years

Epitope: epitope of mAb b96.11
Chemical type: Discontinuous protein residues
Discontinuous residues: D305, E306, R307, T338, T339, V340, Y341, F344, S374, R375, K376, W456, L457, K498, P499, Q500
Source molecule (GenBank): Q05329.1
Assay category: BCell
Result: Positive
Host: M 28 years
Reference: Jean M Jasinski; Liping Yu; Maki Nakayama; Marcella M Li; Myra A Lipes; George S Eisenbarth; Edwin Liu. "Transgenic insulin (B:9-23) T-cell receptor mice develop autoimmune diabetes dependent upon RAG genotype, H-2g7 homozygosity, and insulin 2 gene knockout." Diabetes (2006).

Epitope: insulin B chain (B:9-23)
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo
Reference: Anthony Quinn; Marcia McInerney; Donald Huffman; Brigid McInerney; Stella Mayo; Kathryn Haskins; Eli Sercarz. "T cells to a dominant epitope of GAD65 express a public CDR3 motif." International immunology (2006).

Epitope: GAD65 530-543
Chemical type: Peptide from protein
Sequence: APVIKARMMEY
Position: 530-540
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: GAD65 530-543
Chemical type: Peptide from protein
Sequence: APVIKARMMEY
Position: 530-540
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: GAD65 530-543
Chemical type: Peptide from protein
Sequence: APVIKARMMEY
Position: 530-540
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive
Host: F 
Cell type: T cell
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: GAD65 530-543
Chemical type: Peptide from protein
Sequence: APVIKARMMEY
Position: 530-540
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive
Host: F
Reference: Thomas O Ola; Paul A Biro; Mohammed I Hawa; Johnny Ludvigsson; Mattia Locatelli; Maria Ausiliatrice Puglisi; Gian Franco Bottazzo; Alessandra Fierabracci. "Importin beta: a novel autoantigen in human autoimmunity identified by screening random peptide libraries on phage." Journal of autoimmunity (2006).

Epitope: 195Dyn phagotope
Chemical type: Peptide, no natural source
Sequence: CHAVKVGNPSC
Assay category: BCell
Result: Positive
Host:  3-4 weeks

Epitope: 195Dyn phagotope
Chemical type: Peptide, no natural source
Sequence: CHAVKVGNPSC
Assay category: BCell
Result: Positive
Host:  3-4 weeks

Epitope: 195Dyn phagotope
Chemical type: Peptide, no natural source
Sequence: CHAVKVGNPSC
Assay category: BCell
Result: Positive
Host:  3-4 weeks

Epitope: 195Dyn phagotope
Chemical type: Peptide, no natural source
Sequence: CHAVKVGNPSC
Assay category: BCell
Result: Positive

Epitope: 195Dyn phagotope
Chemical type: Peptide, no natural source
Sequence: CHAVKVGNPSC
Assay category: BCell
Result: Positive
Host:  3-4 weeks

Epitope: 195Dyn phagotope
Chemical type: Peptide, no natural source
Sequence: CHAVKVGNPSC
Assay category: BCell
Result: Negative
Reference: Sandra Piquer; Lionel Valera; Vito Lampasona; Bénédicte Jardin-Watelet; Stéphanie Roche; Claude Granier; Francoise Roquet; Michael R Christie; Tiziana Giordano; Maria-Luisa Malosio; Ezio Bonifacio; Daniel Laune. "Monoclonal antibody 76F distinguishes IA-2 from IA-2beta and overlaps an autoantibody epitope." Journal of autoimmunity (2006).

Epitope: 76F mAb epitope
Chemical type: Peptide from protein
Sequence: FEYQD
Position: 626-630
Source molecule (GenBank): Q16849.1
Assay category: BCell
Result: Positive
Host:  6 weeks

Epitope: 76F mAb epitope
Chemical type: Peptide from protein
Sequence: FEYQD
Position: 626-630
Source molecule (GenBank): Q16849.1
Assay category: BCell
Result: Positive
Host:  6 weeks

Epitope: 76F mAb epitope
Chemical type: Peptide from protein
Sequence: FEYQD
Position: 626-630
Source molecule (GenBank): Q16849.1
Assay category: BCell
Result: Positive
Quantitative measurement: 92.0
Host:  6 weeks

Epitope: A9 mAb epitope
Chemical type: Peptide from protein
Sequence: WQALCAYQAE
Position: 713-722
Source molecule (GenBank): Q16849.1
Assay category: BCell
Result: Positive
Host:  6 weeks

Epitope: A9 mAb epitope
Chemical type: Peptide from protein
Sequence: WQALCAYQAE
Position: 713-722
Source molecule (GenBank): Q16849.1
Assay category: BCell
Result: Positive
Host:  6 weeks

Epitope: A9 mAb epitope
Chemical type: Peptide from protein
Sequence: WQALCAYQAE
Position: 713-722
Source molecule (GenBank): Q16849.1
Assay category: BCell
Result: Positive
Quantitative measurement: 95.0
Host:  6 weeks
Reference: Carmen P Wong; Li Li; Jeffrey A Frelinger; Roland Tisch. "Early autoimmune destruction of islet grafts is associated with a restricted repertoire of IGRP-specific CD8+ T cells in diabetic nonobese diabetic mice." Journal of immunology (Baltimore, Md. : 1950) (2006).

Epitope: IGRP206–214
Chemical type: Peptide from protein
Sequence: VYLKTNVFL
Position: 206-214
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Positive

Epitope: IGRP206–214
Chemical type: Peptide from protein
Sequence: VYLKTNVFL
Position: 206-214
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Positive
Host: F 20 weeks
Cell type: T cell
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: IGRP206–214
Chemical type: Peptide from protein
Sequence: VYLKTNVFL
Position: 206-214
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: InsB15–23
Chemical type: Peptide from protein
Sequence: LYLVCGERG
Position: 15-23
Source molecule (GenBank): 1XDA_B
Assay category: TCell
Result: Negative
Host: F 20 weeks
Cell type: T cell
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: InsB15–23
Chemical type: Peptide from protein
Sequence: LYLVCGERG
Position: 15-23
Source molecule (GenBank): 1XDA_B
Assay category: TCell
Result: Positive-Low
Host: F 20 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: proinsulin
Chemical type: Peptide from protein
Sequence: FYTPMSRREV
Position: 49-58
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Negative
Host: F 20 weeks
Cell type: T cell
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: DMK138–146
Chemical type: Peptide from protein
Sequence: FQDENYLYL
Position: 138-146
Source molecule (GenBank): NP_115794.1
Assay category: TCell
Result: Negative
Host: F 20 weeks
Cell type: T cell
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: NRP-V7
Chemical type: Peptide, no natural source
Sequence: KYNKANVFL
Assay category: TCell
Result: Positive
Host: F 20 weeks
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: NRP-V7
Chemical type: Peptide, no natural source
Sequence: KYNKANVFL
Assay category: TCell
Result: Positive
Host: F 20 weeks
Cell type: T cell
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: NRP-V7
Chemical type: Peptide, no natural source
Sequence: KYNKANVFL
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo
Reference: Viveka Oling; Jane Marttila; Jorma Ilonen; William W Kwok; Gerald Nepom; Mikael Knip; Olli Simell; Helena Reijonen. "GAD65- and proinsulin-specific CD4+ T-cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects." Journal of autoimmunity (2005).

Epitope: GAD65 555-567 557I
Chemical type: Peptide, no natural source
Sequence: NFIRMVISNPAAT
Assay category: TCell
Result: Positive
Host:  median: 6.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GAD65 555-567 557I
Chemical type: Peptide, no natural source
Sequence: NFIRMVISNPAAT
Assay category: TCell
Result: Negative
Host:  median: 5.5 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GAD65 555-567 557I
Chemical type: Peptide, no natural source
Sequence: NFIRMVISNPAAT
Assay category: TCell
Result: Positive
Host:  median: 11.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GAD56 (274-286)
Chemical type: Peptide from protein
Sequence: IAFTSEHSHFSLK
Position: 274-286
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Host:  median: 5.5 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GAD56 (274-286)
Chemical type: Peptide from protein
Sequence: IAFTSEHSHFSLK
Position: 274-286
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Positive
Host:  median: 11.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GAD56 (274-286)
Chemical type: Peptide from protein
Sequence: IAFTSEHSHFSLK
Position: 274-286
Source molecule (GenBank): Q05329.1
Assay category: TCell
Result: Negative
Host:  median: 6.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Proinsulin (24-36)
Chemical type: Peptide from protein
Sequence: FFYTPKTRREAED
Position: 48-60
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Negative
Host:  median: 6.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Proinsulin (24-36)
Chemical type: Peptide from protein
Sequence: FFYTPKTRREAED
Position: 48-60
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  median: 11.3 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Proinsulin (24-36)
Chemical type: Peptide from protein
Sequence: FFYTPKTRREAED
Position: 48-60
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  median: 5.5 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated
Reference: Yang D Dai; Kent P Jensen; Agnes Lehuen; Emma L Masteller; Jeffrey A Bluestone; Darcy B Wilson; Eli E Sercarz. "A peptide of glutamic acid decarboxylase 65 can recruit and expand a diabetogenic T cell clone, BDC2.5, in the pancreas." Journal of immunology (Baltimore, Md. : 1950) (2005).

Epitope: GAD65 p524-543
Chemical type: Peptide from protein
Sequence: SRLSKVAPVIKARMMEYGTT
Position: 524-543
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive

Epitope: GAD65 p524-543
Chemical type: Peptide from protein
Sequence: SRLSKVAPVIKARMMEYGTT
Position: 524-543
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive-Low
Host: F 6-8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: GAD65 p524-543
Chemical type: Peptide from protein
Sequence: SRLSKVAPVIKARMMEYGTT
Position: 524-543
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: GAD65 p524-543
Chemical type: Peptide from protein
Sequence: SRLSKVAPVIKARMMEYGTT
Position: 524-543
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: GAD65 p524-543
Chemical type: Peptide from protein
Sequence: SRLSKVAPVIKARMMEYGTT
Position: 524-543
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive-Low
Host: F 6-8 weeks
Cell type: T cell
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: m1040-31
Chemical type: Peptide, no natural source
Sequence: YVRPLWVRME
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: m1040-31
Chemical type: Peptide, no natural source
Sequence: YVRPLWVRME
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: m1040-31
Chemical type: Peptide, no natural source
Sequence: YVRPLWVRME
Assay category: TCell
Result: Negative

Epitope: m1040-31
Chemical type: Peptide, no natural source
Sequence: YVRPLWVRME
Assay category: TCell
Result: Positive-High
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo
Reference: Bingye Han; Pau Serra; Jun Yamanouchi; Abdelaziz Amrani; John F Elliott; Peter Dickie; Teresa P Dilorenzo; Pere Santamaria. "Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes." The Journal of clinical investigation (2005).

Epitope: IGRP<sub>206-214</sub>
Chemical type: Peptide from protein
Sequence: VYLKTNVFL
Position: 206-214
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Positive
Host:  9-20 weeks
Cell type: T cell hybridoma
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: IGRP<sub>206-214</sub>
Chemical type: Peptide from protein
Sequence: VYLKTNVFL
Position: 206-214
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Positive
Host:  9-20 weeks
Cell type: T cell hybridoma
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: IGRP<sub>206-214</sub>
Chemical type: Peptide from protein
Sequence: VYLKTNVFL
Position: 206-214
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Positive
Host:  9-20 weeks
Cell type: T cell hybridoma
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: NRP-V7
Chemical type: Peptide, no natural source
Sequence: KYNKANVFL
Assay category: TCell
Result: Positive
Host:  9-20 weeks
Cell type: T cell hybridoma
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: NRP-V7
Chemical type: Peptide, no natural source
Sequence: KYNKANVFL
Assay category: TCell
Result: Positive
Host:  9-20 weeks
Cell type: T cell hybridoma
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: NRP-V7
Chemical type: Peptide, no natural source
Sequence: KYNKANVFL
Assay category: TCell
Result: Positive
Host:  9-20 weeks
Cell type: T cell hybridoma
Tissue: pancreas
Culture conditions: Direct Ex Vivo
Reference: Sally C Kent; Yahua Chen; Lisa Bregoli; Sue M Clemmings; Norma Sue Kenyon; Camillo Ricordi; Bernhard J Hering; David A Hafler. "Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope." Nature (2005).

Epitope: A1-15
Chemical type: Peptide from protein
Sequence: GIVEQCCTSICSLYQ
Position: 90-104
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: A1-15
Chemical type: Peptide from protein
Sequence: GIVEQCCTSICSLYQ
Position: 90-104
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone
Reference: Erik A Ranheim; Kristin V Tarbell; Michelle Krogsgaard; Valérie Mallet-Designe; Luc Teyton; Hugh O McDevitt; Irving L Weissman. "Selection of aberrant class II restricted CD8+ T cells in NOD mice expressing a glutamic acid decarboxylase (GAD)65-specific T cell receptor transgene." Autoimmunity (2004).

Epitope: Mouse GAD65 (286-300)
Chemical type: Peptide from protein
Sequence: KKGAAALGIGTDSVI
Position: 286-300
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Mouse GAD65 (286-300)
Chemical type: Peptide from protein
Sequence: KKGAAALGIGTDSVI
Position: 286-300
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive
Host:  12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Mouse GAD65 (286-300)
Chemical type: Peptide from protein
Sequence: KKGAAALGIGTDSVI
Position: 286-300
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Negative
Host:  12 weeks
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Mouse GAD65 (286-300)
Chemical type: Peptide from protein
Sequence: KKGAAALGIGTDSVI
Position: 286-300
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Negative

Epitope: Mouse GAD65 (286-300)
Chemical type: Peptide from protein
Sequence: KKGAAALGIGTDSVI
Position: 286-300
Source molecule (GenBank): P48320.1
Assay category: TCell
Result: Positive
Host:  12 weeks
Cell type: T cell CD8+
Tissue: lymph node
Culture conditions: Direct Ex Vivo