Reference: Jiefei Han; Ruofei Yu; Jianchun Duan; Jin Li; Wei Zhao; Guoshuang Feng; Hua Bai; Yuqi Wang; Xue Zhang; Rui Wan; Jiachen Xu; Xin Wang; Yanfang Guan; Xuefeng Xia; Zhuoran Yao; Kailun Fei; David P Carbone; Zhijie Wang; Jie Wang. "Weighting tumor-specific TCR repertoires as a classifier to stratify the immunotherapy delivery in non-small cell lung cancers." Science advances (2021).

Epitope: MANA 1
Chemical type: Peptide, no natural source
Sequence: APEAVTMPA
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 1 wt
Chemical type: Peptide from protein
Sequence: AAREGFLDT
Position: 34-42
Source molecule (GenBank): K7ES20
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 2
Chemical type: Peptide, no natural source
Sequence: MVGMNRRPI
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 4
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MANA 4
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MANA 4
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MANA 4
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 5
Chemical type: Peptide, no natural source
Sequence: WPILTIITL
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 6
Chemical type: Peptide, no natural source
Sequence: AAREGFLDK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 7
Chemical type: Peptide, no natural source
Sequence: VAAETGIPF
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 8
Chemical type: Peptide, no natural source
Sequence: FGITYYMEW
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 9
Chemical type: Peptide, no natural source
Sequence: STFDTQITQK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 10
Chemical type: Peptide, no natural source
Sequence: AAIPPPPPLR
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 11
Chemical type: Peptide, no natural source
Sequence: GSLLSATEK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 2 wt
Chemical type: Peptide from protein
Sequence: MGGMNRRPI
Position: 204-212
Source molecule (GenBank): A0A0U1RQC9.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 3 wt
Chemical type: Peptide from protein
Sequence: ARNDFLKEI
Position: 618-626
Source molecule (GenBank): Q16832.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 4 wt
Chemical type: Peptide from protein
Sequence: VVGAGGVGK
Position: 8-16
Source molecule (GenBank): G3V4K2.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MANA 4 wt
Chemical type: Peptide from protein
Sequence: VVGAGGVGK
Position: 8-16
Source molecule (GenBank): G3V4K2.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MANA 4 wt
Chemical type: Peptide from protein
Sequence: VVGAGGVGK
Position: 8-16
Source molecule (GenBank): G3V4K2.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 5 wt
Chemical type: Peptide from protein
Sequence: RPILTIITL
Position: 210-218
Source molecule (GenBank): A0A0U1RQC9.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 6 wt
Chemical type: Peptide from protein
Sequence: AAREGFLDT
Position: 34-42
Source molecule (GenBank): K7ES20
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 7 wt
Chemical type: Peptide from protein
Sequence: GAAETGIPF
Position: 70-78
Source molecule (GenBank): O15119.4
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 8 wt
Chemical type: Peptide from protein
Sequence: FGITYYMER
Position: 2301-2309
Source molecule (GenBank): A0A0A0MQS6
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 9 wt
Chemical type: Peptide from protein
Sequence: STFDTQITKK
Position: 1861-1870
Source molecule (GenBank): P78527.3
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 10 wt
Chemical type: Peptide from protein
Sequence: AAIPPPPPLP
Position: 951-960
Source molecule (GenBank): Q9NZ56.4
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 11 wt
Chemical type: Peptide from protein
Sequence: GSLLAATEK
Position: 101-109
Source molecule (GenBank): E9PPL6
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 12
Chemical type: Peptide, no natural source
Sequence: KAVLTGELF
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 13
Chemical type: Peptide, no natural source
Sequence: KQESDWNVLK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 14
Chemical type: Peptide, no natural source
Sequence: YYIMGEAEGF
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 12 wt
Chemical type: Peptide from protein
Sequence: NAVLTGELF
Position: 2285-2293
Source molecule (GenBank): H7BXU2.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 13 wt
Chemical type: Peptide from protein
Sequence: KQESDWKVLK
Position: 696-705
Source molecule (GenBank): A0A2R8YDR3.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: MANA 14 wt
Chemical type: Peptide from protein
Sequence: YYITGEAEGF
Position: 582-591
Source molecule (GenBank): P03372.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated