Reference: Dyantha I van der Lee; Georgia Koutsoumpli; Rogier M Reijmers; M Willy Honders; Rob C M de Jong; Dennis F G Remst; Tassilo L A Wachsmann; Renate S Hagedoorn; Kees L M C Franken; Michel G D Kester; Karl J Harber; Lisanne M Roelofsen; Annemiek M Schouten; Arend Mulder; Jan W Drijfhout; Hendrik Veelken; Peter A van Veelen; Mirjam H M Heemskerk; J H Frederik Falkenburg; Marieke Griffioen. "An HLA-A*11:01-Binding Neoantigen from Mutated NPM1 as Target for TCR Gene Therapy in AML." Cancers (2021).

Epitope: HIV peptide
Chemical type: Peptide from protein
Sequence: QVPLRPMTYK
Position: 72-81
Source molecule (GenBank): Q9WPU2.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 304.09

Epitope: HIV peptide
Chemical type: Peptide from protein
Sequence: QVPLRPMTYK
Position: 72-81
Source molecule (GenBank): Q9WPU2.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 51.18

Epitope: dNPM1
Chemical type: Peptide, no natural source
Sequence: AVEEVSLRK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: dNPM1
Chemical type: Peptide, no natural source
Sequence: AVEEVSLRK
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Engineered

Epitope: dNPM1
Chemical type: Peptide, no natural source
Sequence: AVEEVSLRK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: dNPM1
Chemical type: Peptide, no natural source
Sequence: AVEEVSLRK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: dNPM1
Chemical type: Peptide, no natural source
Sequence: AVEEVSLRK
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: dNPM1
Chemical type: Peptide, no natural source
Sequence: AVEEVSLRK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: dNPM1
Chemical type: Peptide, no natural source
Sequence: AVEEVSLRK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: dNPM1
Chemical type: Peptide, no natural source
Sequence: AVEEVSLRK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: dNPM1
Chemical type: Peptide, no natural source
Sequence: AVEEVSLRK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: dNPM1
Chemical type: Peptide, no natural source
Sequence: AVEEVSLRK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: dNPM1
Chemical type: Peptide, no natural source
Sequence: AVEEVSLRK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: dNPM1
Chemical type: Peptide, no natural source
Sequence: AVEEVSLRK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: dNPM1
Chemical type: Peptide, no natural source
Sequence: AVEEVSLRK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 50.85

Epitope: dNPM1
Chemical type: Peptide, no natural source
Sequence: AVEEVSLRK
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1332.47