Reference: Sebastian Spindeldreher; Anette Karle; Evelyne Correia; Maxime Tenon; Sascha Gottlieb; Thomas Huber; Bernard Maillere; Frank Kolbinger. "T cell epitope mapping of secukinumab and ixekizumab in healthy donors." mAbs (2020).

Epitope: Ixekizumab heavy P 83
Chemical type: Peptide from protein
Sequence: ADESTSTAYMELSSLRSEDTA
Position: 72-92
Source molecule (GenBank): 21669745
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 71
Chemical type: Peptide from protein
Sequence: ADYEKHKVYACEVTH
Position: 185-199
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 72
Chemical type: Peptide from protein
Sequence: ADYEKHKVYACEVTHQ
Position: 185-200
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 143
Chemical type: Peptide from protein
Sequence: ADYEKHKVYACEVTHQGLSSPV
Position: 189-210
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 174
Chemical type: Peptide from protein
Sequence: ADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
Position: 189-219
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 151
Chemical type: Peptide from protein
Sequence: AEDVGVYYCSQSTHLP
Position: 85-100
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 113
Chemical type: Peptide from protein
Sequence: AINQDGSEKYYVGS
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 64
Chemical type: Peptide from protein
Sequence: AKNSLYLQMNSLRVED
Position: 53-68
Source molecule (GenBank): 662357801
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 41
Chemical type: Peptide from protein
Sequence: AKNSLYLQMNSLRVEDT
Position: 75-91
Source molecule (GenBank): 519672386
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 31
Chemical type: Peptide from protein
Sequence: AKNSLYLQMNSLRVEDTA
Position: 61-78
Source molecule (GenBank): 4456588
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 60
Chemical type: Peptide from protein
Sequence: AKVQWKVDNALQSGNS
Position: 145-160
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab P 111
Chemical type: Peptide from protein
Sequence: AKVQWKVDNALQSGNSQESVTEQD
Position: 145-168
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 2
Chemical type: Peptide from protein
Sequence: ALHNHYTQKSLSLSLG
Position: 201-216
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 8
Chemical type: Peptide from protein
Sequence: ALHNHYTQKSLSLSPG
Position: 440-455
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 29
Chemical type: Peptide from protein
Sequence: ALHNHYTQKSLSLSPGK
Position: 440-456
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 41
Chemical type: Peptide from protein
Sequence: ALQSGNSQESVTEQD
Position: 175-189
Source molecule (GenBank): CAA75031.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 144
Chemical type: Peptide from protein
Sequence: APGKGLEWVAAINQD
Position: 42-56
Source molecule (GenBank): 106897113
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 86
Chemical type: Peptide from protein
Sequence: APGKGLEWVAAINQDGSEK
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 63
Chemical type: Peptide from protein
Sequence: APRLLIYGASSR
Position: 44-55
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 53
Chemical type: Peptide from protein
Sequence: APRLLIYGASSRA
Position: 44-56
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 54
Chemical type: Peptide from protein
Sequence: APRLLIYGASSRAT
Position: 44-57
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 55
Chemical type: Peptide from protein
Sequence: APRLLIYGASSRATG
Position: 64-78
Source molecule (GenBank): P01619.2
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 56
Chemical type: Peptide from protein
Sequence: APRLLIYGASSRATGIPD
Position: 44-61
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 147
Chemical type: Peptide from protein
Sequence: DGSFFLYSKLTVDKSR
Position: 410-425
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 130
Chemical type: Peptide from protein
Sequence: DIAVEWESNGQPENNYK
Position: 385-401
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 94
Chemical type: Peptide from protein
Sequence: DIVMTQTPLS
Position: 1-10
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 45
Chemical type: Peptide from protein
Sequence: DIVMTQTPLSL
Position: 1-11
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 68
Chemical type: Peptide from protein
Sequence: DIVMTQTPLSLS
Position: 1-12
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 133
Chemical type: Peptide from protein
Sequence: DIVMTQTPLSLSVT
Position: 1-14
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 64
Chemical type: Peptide from protein
Sequence: DIVMTQTPLSLSVTPG
Position: 1-16
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 24
Chemical type: Peptide from protein
Sequence: DIVMTQTPLSLSVTPGQ
Position: 1-17
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 82
Chemical type: Peptide from protein
Sequence: DIVMTQTPLSLSVTPGQPA
Position: 1-19
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 52
Chemical type: Peptide from protein
Sequence: DIVMTQTPLSLSVTPGQPAS
Position: 1-20
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 79
Chemical type: Peptide from protein
Sequence: DIVMTQTPLSLSVTPGQPASI
Position: 1-21
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 23
Chemical type: Peptide from protein
Sequence: DLWGRGTLVTVSSA
Position: 109-122
Source molecule (GenBank): 8250273
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 20
Chemical type: Peptide from protein
Sequence: DLWGRGTLVTVSSASTKGPSVFPLAPSSK
Position: 97-125
Source molecule (GenBank): 86438950
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 133
Chemical type: Peptide from protein
Sequence: DLWGRGTLVTVSSASTKGPSVFPLAPSSKS
Position: 97-126
Source molecule (GenBank): 86438950
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 46
Chemical type: Peptide from protein
Sequence: DNAKNSLYLQMNSLRVED
Position: 73-90
Source molecule (GenBank): 118406433
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 30
Chemical type: Peptide from protein
Sequence: DNAKNSLYLQMNSLRVEDTA
Position: 57-76
Source molecule (GenBank): 815084992
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 92
Chemical type: Peptide from protein
Sequence: DSDGSFFLYSRLTVDKS
Position: 341-357
Source molecule (GenBank): 9857759
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 93
Chemical type: Peptide from protein
Sequence: DSDGSFFLYSRLTVDKSR
Position: 314-331
Source molecule (GenBank): 10334595
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab P 70
Chemical type: Peptide from protein
Sequence: DSKDSTYSLSSTLTLSK
Position: 168-184
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 43
Chemical type: Peptide from protein
Sequence: DSKDSTYSLSSTLTLSKA
Position: 168-185
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 102
Chemical type: Peptide from protein
Sequence: DSTYSLSSTLTLSKA
Position: 171-185
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 28
Chemical type: Peptide from protein
Sequence: DVGVYYCSQSTHLPF
Position: 87-101
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 1
Chemical type: Peptide from protein
Sequence: DVGVYYCSQSTHLPFT
Position: 87-102
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 97
Chemical type: Peptide from protein
Sequence: DYEKHKVYACEVTHQGLSSPV
Position: 186-206
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 115
Chemical type: Peptide from protein
Sequence: EAKVQWKVDNALQSGNS
Position: 148-164
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 3
Chemical type: Peptide from protein
Sequence: EALHNHYTQKSLSLSLG
Position: 200-216
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 9
Chemical type: Peptide from protein
Sequence: EALHNHYTQKSLSLSPG
Position: 439-455
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 92
Chemical type: Peptide from protein
Sequence: EALHNHYTQKSLSLSPGK
Position: 439-456
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 87
Chemical type: Peptide from protein
Sequence: EDTAVYYCARYDY
Position: 68-80
Source molecule (GenBank): 270046958
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 88
Chemical type: Peptide from protein
Sequence: EDTAVYYCARYDYFTG
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 149
Chemical type: Peptide from protein
Sequence: EDVGVYYCSQSTHL
Position: 86-99
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 59
Chemical type: Peptide from protein
Sequence: EDVGVYYCSQSTHLPF
Position: 86-101
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 16
Chemical type: Peptide from protein
Sequence: EDVGVYYCSQSTHLPFT
Position: 86-102
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 21
Chemical type: Peptide from protein
Sequence: EIVLTQSPGTL
Position: 1-11
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 14
Chemical type: Peptide from protein
Sequence: EIVLTQSPGTLSL
Position: 1-13
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 18
Chemical type: Peptide from protein
Sequence: EIVLTQSPGTLSLS
Position: 1-14
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 31
Chemical type: Peptide from protein
Sequence: EIVLTQSPGTLSLSPGE
Position: 1-17
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 3
Chemical type: Peptide from protein
Sequence: EIVLTQSPGTLSLSPGER
Position: 1-18
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 1
Chemical type: Peptide from protein
Sequence: EIVLTQSPGTLSLSPGERA
Position: 1-19
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 22
Chemical type: Peptide from protein
Sequence: EIVLTQSPGTLSLSPGERATL
Position: 1-21
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 9
Chemical type: Peptide from protein
Sequence: EIVLTQSPGTLSLSPGERATLS
Position: 1-22
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 96
Chemical type: Peptide from protein
Sequence: EIVLTQSPGTLSLSPGERATLSCRAS
Position: 1-26
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 113
Chemical type: Peptide from protein
Sequence: EIVLTQSPGTLSLSPGERATLSCRASQSVS
Position: 1-30
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 89
Chemical type: Peptide from protein
Sequence: EIVLTQSPGTLSLSPGERATLSCRASQSVSS
Position: 1-31
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 116
Chemical type: Peptide from protein
Sequence: EKHKVYACEVTHQG
Position: 192-205
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 93
Chemical type: Peptide from protein
Sequence: EKHKVYACEVTHQGLS
Position: 192-207
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 37
Chemical type: Peptide from protein
Sequence: EKHKVYACEVTHQGLSSPV
Position: 188-206
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 145
Chemical type: Peptide from protein
Sequence: EQDSKDSTYSLSSTLTLSK
Position: 170-188
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 57
Chemical type: Peptide from protein
Sequence: EQDSKDSTYSLSSTLTLSKA
Position: 166-185
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 45
Chemical type: Peptide from protein
Sequence: ESNGQPENNYKTTPPVLD
Position: 391-408
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 42
Chemical type: Peptide from protein
Sequence: ESNGQPENNYKTTPPVLDSD
Position: 391-410
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 96
Chemical type: Peptide from protein
Sequence: ESTSTAYMELSSLRSE
Position: 74-89
Source molecule (GenBank): 21669745
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 51
Chemical type: Peptide from protein
Sequence: ESTSTAYMELSSLRSED
Position: 74-90
Source molecule (GenBank): 21669745
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 61
Chemical type: Peptide from protein
Sequence: ESTSTAYMELSSLRSEDT
Position: 74-91
Source molecule (GenBank): 21669745
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 48
Chemical type: Peptide from protein
Sequence: ESTSTAYMELSSLRSEDTA
Position: 74-92
Source molecule (GenBank): 21669745
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 116
Chemical type: Peptide from protein
Sequence: EVQLVESGGGL
Position: 1-11
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 5
Chemical type: Peptide from protein
Sequence: EVQLVESGGGLVQPG
Position: 1-15
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 15
Chemical type: Peptide from protein
Sequence: EVQLVESGGGLVQPGG
Position: 1-16
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 75
Chemical type: Peptide from protein
Sequence: EVQLVESGGGLVQPGGS
Position: 1-17
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 62
Chemical type: Peptide from protein
Sequence: EVQLVESGGGLVQPGGSLR
Position: 1-19
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 37
Chemical type: Peptide from protein
Sequence: EVQLVESGGGLVQPGGSLRL
Position: 1-20
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 35
Chemical type: Peptide from protein
Sequence: EVQLVESGGGLVQPGGSLRLS
Position: 1-21
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 156
Chemical type: Peptide from protein
Sequence: EVTHQGLSSPVTKSFNRGEC
Position: 200-219
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 114
Chemical type: Peptide from protein
Sequence: FFLYSRLTVDKSR
Position: 319-331
Source molecule (GenBank): 10334595
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 105
Chemical type: Peptide from protein
Sequence: FLYSRLTVDKSR
Position: 320-331
Source molecule (GenBank): 10334595
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 137
Chemical type: Peptide from protein
Sequence: FSGSGSGTDFTLKISRVEAEDVG
Position: 67-89
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 65
Chemical type: Peptide from protein
Sequence: FTLKISRVEAED
Position: 76-87
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 40
Chemical type: Peptide from protein
Sequence: FTLTISRLEPED
Position: 72-83
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 176
Chemical type: Peptide from protein
Sequence: FYPREAKVQWKVDNALQSGNSQESVTEQD
Position: 144-172
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 140
Chemical type: Peptide from protein
Sequence: GGPSVFLFPPKPKD
Position: 245-258
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 115
Chemical type: Peptide from protein
Sequence: GLEWVAAINQDGSEK
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 72
Chemical type: Peptide from protein
Sequence: GLPSSIEKTISKAKGQPR
Position: 97-114
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 73
Chemical type: Peptide from protein
Sequence: GLPSSIEKTISKAKGQPREPQ
Position: 97-117
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 17
Chemical type: Peptide from protein
Sequence: GNSQESVTEQDSKD
Position: 158-171
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 73
Chemical type: Peptide from protein
Sequence: GNTYLHWYLQKPGQSPQ
Position: 34-50
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 128
Chemical type: Peptide from protein
Sequence: GNTYLHWYLQKPGQSPQL
Position: 34-51
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 129
Chemical type: Peptide from protein
Sequence: GNTYLHWYLQKPGQSPQLLI
Position: 34-53
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 90
Chemical type: Peptide from protein
Sequence: GQAPRLLIYGASSRA
Position: 42-56
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 92
Chemical type: Peptide from protein
Sequence: GQAPRLLIYGASSRAT
Position: 42-57
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 30
Chemical type: Peptide from protein
Sequence: GQAPRLLIYGASSRATG
Position: 42-58
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 65
Chemical type: Peptide from protein
Sequence: GQAPRLLIYGASSRATGIPD
Position: 42-61
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 118
Chemical type: Peptide from protein
Sequence: GQGTLVTVSSASTKG
Position: 130-144
Source molecule (GenBank): QBK47431.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 70
Chemical type: Peptide from protein
Sequence: GQPENNYKTTPPVLD
Position: 394-408
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 62
Chemical type: Peptide from protein
Sequence: GQSPQLLIYKVSNRFIG
Position: 46-62
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 92
Chemical type: Peptide from protein
Sequence: GQSPQLLIYKVSNRFIGVPDR
Position: 46-66
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 124
Chemical type: Peptide from protein
Sequence: GRGTLVTVSS
Position: 132-141
Source molecule (GenBank): 346139
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 1
Chemical type: Peptide from protein
Sequence: GRGTLVTVSSA
Position: 112-122
Source molecule (GenBank): 8250273
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 96
Chemical type: Peptide from protein
Sequence: GRGTLVTVSSASTK
Position: 105-118
Source molecule (GenBank): 4426734
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 136
Chemical type: Peptide from protein
Sequence: GRGTLVTVSSASTKG
Position: 112-126
Source molecule (GenBank): 8250273
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 81
Chemical type: Peptide from protein
Sequence: GRGTLVTVSSASTKGPSVFPLAPSSK
Position: 117-142
Source molecule (GenBank): 323432279
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 121
Chemical type: Peptide from protein
Sequence: GSEKYYVGSVKG
Position: 12-23
Source molecule (GenBank): 2808892
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 43
Chemical type: Peptide from protein
Sequence: GSEKYYVGSVKGRFTISRD
Position: 12-30
Source molecule (GenBank): 2808892
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 33
Chemical type: Peptide from protein
Sequence: GSFFLYSKLTVDKSR
Position: 411-425
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 97
Chemical type: Peptide from protein
Sequence: GSFFLYSRLTVD
Position: 317-328
Source molecule (GenBank): 10334595
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 27
Chemical type: Peptide from protein
Sequence: GSFFLYSRLTVDKSR
Position: 317-331
Source molecule (GenBank): 10334595
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 98
Chemical type: Peptide from protein
Sequence: GSFFLYSRLTVDKSRWQEG
Position: 317-335
Source molecule (GenBank): 10334595
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 138
Chemical type: Peptide from protein
Sequence: GSGSGTDFTLKISRVEAE
Position: 69-86
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 90
Chemical type: Peptide from protein
Sequence: GSGSGTDFTLKISRVEAEDVG
Position: 69-89
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 119
Chemical type: Peptide from protein
Sequence: GSGTDFTLKISRVEA
Position: 71-85
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 91
Chemical type: Peptide from protein
Sequence: GSGTDFTLKISRVEAED
Position: 71-87
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 103
Chemical type: Peptide from protein
Sequence: GSGTDFTLTISRLEPED
Position: 67-83
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 104
Chemical type: Peptide from protein
Sequence: GSGTDFTLTISRLEPEDF
Position: 67-84
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 120
Chemical type: Peptide from protein
Sequence: GTDFTLKISRVEAED
Position: 73-87
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 118
Chemical type: Peptide from protein
Sequence: GTDFTLTISRLEPE
Position: 69-82
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 61
Chemical type: Peptide from protein
Sequence: GTQTYICNVNHKPSN
Position: 203-217
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 73
Chemical type: Peptide from protein
Sequence: GVEVHNAKTK
Position: 290-299
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 139
Chemical type: Peptide from protein
Sequence: GVEVHNAKTKPRE
Position: 290-302
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 77
Chemical type: Peptide from protein
Sequence: GVEVHNAKTKPREE
Position: 290-303
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 71
Chemical type: Peptide from protein
Sequence: GVEVHNAKTKPREEQ
Position: 290-304
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 7
Chemical type: Peptide from protein
Sequence: HEALHNHYTQKSLSLSLG
Position: 199-216
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 7
Chemical type: Peptide from protein
Sequence: HEALHNHYTQKSLSLSPG
Position: 438-455
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 111
Chemical type: Peptide from protein
Sequence: HKPSNTKVD
Position: 226-234
Source molecule (GenBank): QBK47431.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 112
Chemical type: Peptide from protein
Sequence: HKPSNTKVDKRVE
Position: 226-238
Source molecule (GenBank): QBK47431.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 99
Chemical type: Peptide from protein
Sequence: HKPSNTKVDKRVESK
Position: 87-101
Source molecule (GenBank): 12054078
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 45
Chemical type: Peptide from protein
Sequence: HKPSNTKVDKRVESKY
Position: 87-102
Source molecule (GenBank): 12054078
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 116
Chemical type: Peptide from protein
Sequence: HKPSNTKVDKRVESKYG
Position: 87-103
Source molecule (GenBank): 12054078
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 4
Chemical type: Peptide from protein
Sequence: HNHYTQKSLSLSLG
Position: 215-228
Source molecule (GenBank): CAA04843.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 6
Chemical type: Peptide from protein
Sequence: HNHYTQKSLSLSPG
Position: 442-455
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 24
Chemical type: Peptide from protein
Sequence: HNHYTQKSLSLSPGK
Position: 442-456
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 8
Chemical type: Peptide from protein
Sequence: HYTQKSLSLSLG
Position: 315-326
Source molecule (GenBank): P01861.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 2
Chemical type: Peptide from protein
Sequence: HYTQKSLSLSPG
Position: 444-455
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 10
Chemical type: Peptide from protein
Sequence: HYTQKSLSLSPGK
Position: 444-456
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 67
Chemical type: Peptide from protein
Sequence: IAVEWESNGQPENNYK
Position: 386-401
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 54
Chemical type: Peptide from protein
Sequence: IAVEWESNGQPENNYKTTPPVLD
Position: 386-408
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 49
Chemical type: Peptide from protein
Sequence: IAVEWESNGQPENNYKTTPPVLDSD
Position: 386-410
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 90
Chemical type: Peptide from protein
Sequence: ISRDNAKNSLYLQMNSLRVEDTA
Position: 56-78
Source molecule (GenBank): 4456588
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 47
Chemical type: Peptide from protein
Sequence: ISRLEPEDFAVY
Position: 76-87
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 24
Chemical type: Peptide from protein
Sequence: ISRLEPEDFAVYY
Position: 76-88
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 44
Chemical type: Peptide from protein
Sequence: ISRLEPEDFAVYYC
Position: 76-89
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 15
Chemical type: Peptide from protein
Sequence: ISRLEPEDFAVYYCQ
Position: 76-90
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 100
Chemical type: Peptide from protein
Sequence: ISRLEPEDFAVYYCQQ
Position: 76-91
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 108
Chemical type: Peptide from protein
Sequence: ISRTPEVTCVVVDVSHEDPE
Position: 262-281
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 155
Chemical type: Peptide from protein
Sequence: ISRVEAEDVGVYYCSQSTHL
Position: 80-99
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 49
Chemical type: Peptide from protein
Sequence: ISRVEAEDVGVYYCSQSTHLPFT
Position: 80-102
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 148
Chemical type: Peptide from protein
Sequence: IYKVSNRFIG
Position: 53-62
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 46
Chemical type: Peptide from protein
Sequence: IYKVSNRFIGVPDR
Position: 53-66
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 85
Chemical type: Peptide from protein
Sequence: KDSTYSLSSTLTL
Position: 170-182
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 86
Chemical type: Peptide from protein
Sequence: KDSTYSLSSTLTLS
Position: 170-183
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 68
Chemical type: Peptide from protein
Sequence: KDSTYSLSSTLTLSKA
Position: 170-185
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 114
Chemical type: Peptide from protein
Sequence: KDSTYSLSSTLTLSKAD
Position: 174-190
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 143
Chemical type: Peptide from protein
Sequence: KGLEWVAAINQD
Position: 45-56
Source molecule (GenBank): 106897113
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 114
Chemical type: Peptide from protein
Sequence: KGLEWVAAINQDGSEK
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 78
Chemical type: Peptide from protein
Sequence: KHKVYACEVTH
Position: 189-199
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 61
Chemical type: Peptide from protein
Sequence: KHKVYACEVTHQGLSSP
Position: 189-205
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 36
Chemical type: Peptide from protein
Sequence: KHKVYACEVTHQGLSSPV
Position: 189-206
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 40
Chemical type: Peptide from protein
Sequence: KNSLYLQMNSLRVEDT
Position: 76-91
Source molecule (GenBank): 62871008
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 47
Chemical type: Peptide from protein
Sequence: KNSLYLQMNSLRVEDTA
Position: 62-78
Source molecule (GenBank): 4456588
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 59
Chemical type: Peptide from protein
Sequence: KPGQAPRLLIYGASS
Position: 40-54
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 25
Chemical type: Peptide from protein
Sequence: KPGQAPRLLIYGASSR
Position: 40-55
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 23
Chemical type: Peptide from protein
Sequence: KPGQAPRLLIYGASSRA
Position: 40-56
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 20
Chemical type: Peptide from protein
Sequence: KPGQAPRLLIYGASSRAT
Position: 40-57
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 13
Chemical type: Peptide from protein
Sequence: KPGQAPRLLIYGASSRATG
Position: 40-58
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 75
Chemical type: Peptide from protein
Sequence: KPGQAPRLLIYGASSRATGIP
Position: 40-60
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 19
Chemical type: Peptide from protein
Sequence: KPGQAPRLLIYGASSRATGIPD
Position: 40-61
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 39
Chemical type: Peptide from protein
Sequence: KPGQAPRLLIYGASSRATGIPDR
Position: 40-62
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 97
Chemical type: Peptide from protein
Sequence: KPGQSPQLLIYKVSNRF
Position: 44-60
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 96
Chemical type: Peptide from protein
Sequence: KPGQSPQLLIYKVSNRFI
Position: 44-61
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 5
Chemical type: Peptide from protein
Sequence: KPGQSPQLLIYKVSNRFIG
Position: 44-62
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: IXE38
Chemical type: Peptide from protein
Sequence: KPGQSPQLLIYKVSNRFIGVPD
Position: 188-209
Source molecule (GenBank): 6NOU_A
Assay category: TCell
Result: Positive
MHC allele types: 419 57
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: IXE38
Chemical type: Peptide from protein
Sequence: KPGQSPQLLIYKVSNRFIGVPD
Position: 188-209
Source molecule (GenBank): 6NOU_A
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 8
Chemical type: Peptide from protein
Sequence: KPGQSPQLLIYKVSNRFIGVPDR
Position: 44-66
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 47
Chemical type: Peptide from protein
Sequence: KPGQSPQLLIYKVSNRFIGVPDRF
Position: 44-67
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 101
Chemical type: Peptide from protein
Sequence: KPGQSPQLLIYKVSNRFIGVPDRFS
Position: 44-68
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 57
Chemical type: Peptide from protein
Sequence: KSLSLSPGK
Position: 448-456
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 70
Chemical type: Peptide from protein
Sequence: KTTPPVLDSD
Position: 414-423
Source molecule (GenBank): QBK47431.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 105
Chemical type: Peptide from protein
Sequence: KVDNALQSGNSQE
Position: 150-162
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 120
Chemical type: Peptide from protein
Sequence: KVDNALQSGNSQESVTE
Position: 150-166
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 77
Chemical type: Peptide from protein
Sequence: KVDNALQSGNSQESVTEQ
Position: 150-167
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 4
Chemical type: Peptide from protein
Sequence: KVDNALQSGNSQESVTEQD
Position: 150-168
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 66
Chemical type: Peptide from protein
Sequence: KVDNALQSGNSQESVTEQDSK
Position: 154-174
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 7
Chemical type: Peptide from protein
Sequence: KVDNALQSGNSQESVTEQDSKD
Position: 150-171
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 66
Chemical type: Peptide from protein
Sequence: KVQWKVDNALQSGNS
Position: 146-160
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 79
Chemical type: Peptide from protein
Sequence: LGTQTYICNVNHKPSN
Position: 202-217
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 1
Chemical type: Peptide from protein
Sequence: LHNHYTQKSLSLSLG
Position: 202-216
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 4
Chemical type: Peptide from protein
Sequence: LHNHYTQKSLSLSPG
Position: 441-455
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 22
Chemical type: Peptide from protein
Sequence: LHNHYTQKSLSLSPGK
Position: 441-456
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 77
Chemical type: Peptide from protein
Sequence: LHWYLQKPGQSPQ
Position: 38-50
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 78
Chemical type: Peptide from protein
Sequence: LHWYLQKPGQSPQL
Position: 38-51
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 130
Chemical type: Peptide from protein
Sequence: LHWYLQKPGQSPQLLI
Position: 38-53
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 55
Chemical type: Peptide from protein
Sequence: LIYKVSNRFIGVPD
Position: 52-65
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 36
Chemical type: Peptide from protein
Sequence: LIYKVSNRFIGVPDR
Position: 52-66
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 95
Chemical type: Peptide from protein
Sequence: LLIYGASSRATG
Position: 47-58
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 82
Chemical type: Peptide from protein
Sequence: LLIYGASSRATGIPDR
Position: 47-62
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 20
Chemical type: Peptide from protein
Sequence: LLIYKVSNRFIGVPD
Position: 51-65
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 21
Chemical type: Peptide from protein
Sequence: LLIYKVSNRFIGVPDR
Position: 51-66
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 38
Chemical type: Peptide from protein
Sequence: LLIYKVSNRFIGVPDRF
Position: 51-67
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 54
Chemical type: Peptide from protein
Sequence: LPSSIEKTISKAKGQPREPQ
Position: 98-117
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 146
Chemical type: Peptide from protein
Sequence: LSKADYEKHKVYACEVTHQGLSSPVT
Position: 186-211
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 149
Chemical type: Peptide from protein
Sequence: LVKDYFPEPVTVSWNSG
Position: 154-170
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 25
Chemical type: Peptide from protein
Sequence: LWGRGTLVTVSSA
Position: 110-122
Source molecule (GenBank): 8250273
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 36
Chemical type: Peptide from protein
Sequence: LWGRGTLVTVSSASTKGPSVFPLAPSSK
Position: 98-125
Source molecule (GenBank): 86438950
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 106
Chemical type: Peptide from protein
Sequence: LYSRLTVDKSR
Position: 321-331
Source molecule (GenBank): 10334595
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 84
Chemical type: Peptide from protein
Sequence: MELSSLRSEDT
Position: 81-91
Source molecule (GenBank): 21669745
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 13
Chemical type: Peptide from protein
Sequence: MHEALHNHYTQKSLSLSLG
Position: 198-216
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 18
Chemical type: Peptide from protein
Sequence: MHEALHNHYTQKSLSLSPG
Position: 437-455
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 126
Chemical type: Peptide from protein
Sequence: MNSLRVEDT
Position: 69-77
Source molecule (GenBank): 4456588
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 99
Chemical type: Peptide from protein
Sequence: NAKNSLYLQMNSLRVED
Position: 60-76
Source molecule (GenBank): 4456588
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab  light P 42
Chemical type: Peptide from protein
Sequence: NALQSGNSQESVTEQ
Position: 153-167
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 5
Chemical type: Peptide from protein
Sequence: NALQSGNSQESVTEQD
Position: 153-168
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 46
Chemical type: Peptide from protein
Sequence: NALQSGNSQESVTEQDSK
Position: 153-170
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 2
Chemical type: Peptide from protein
Sequence: NALQSGNSQESVTEQDSKD
Position: 153-171
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 76
Chemical type: Peptide from protein
Sequence: NALQSGNSQESVTEQDSKDSTYSLSSTLTLSKAD
Position: 153-186
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 177
Chemical type: Peptide from protein
Sequence: NFYPREAKVQWKVDNALQSGNSQESVTEQD
Position: 143-172
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 146
Chemical type: Peptide from protein
Sequence: NGKEYKCKVSNKALPAPI
Position: 324-341
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 75
Chemical type: Peptide from protein
Sequence: NGKEYKCKVSNKGLPS
Position: 85-100
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 5
Chemical type: Peptide from protein
Sequence: NHYTQKSLSLSLG
Position: 204-216
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 3
Chemical type: Peptide from protein
Sequence: NHYTQKSLSLSPG
Position: 443-455
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 16
Chemical type: Peptide from protein
Sequence: NHYTQKSLSLSPGK
Position: 443-456
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 123
Chemical type: Peptide from protein
Sequence: NNYKTTPPVLD
Position: 398-408
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 119
Chemical type: Peptide from protein
Sequence: NNYKTTPPVLDSD
Position: 398-410
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 68
Chemical type: Peptide from protein
Sequence: NSGALTSGVHTFPAVLQS
Position: 181-198
Source molecule (GenBank): QBK47431.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 119
Chemical type: Peptide from protein
Sequence: NSGALTSGVHTFPAVLQSSG
Position: 181-200
Source molecule (GenBank): QBK47431.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 55
Chemical type: Peptide from protein
Sequence: NSLYLQMNSLRVED
Position: 63-76
Source molecule (GenBank): 4456588
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 26
Chemical type: Peptide from protein
Sequence: NSLYLQMNSLRVEDT
Position: 47-61
Source molecule (GenBank): 1360487213
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 56
Chemical type: Peptide from protein
Sequence: NSLYLQMNSLRVEDTA
Position: 63-78
Source molecule (GenBank): 4456588
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 11
Chemical type: Peptide from protein
Sequence: NSQESVTEQDSKD
Position: 159-171
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 76
Chemical type: Peptide from protein
Sequence: NVNHKPSNTKVD
Position: 210-221
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 88
Chemical type: Peptide from protein
Sequence: NYKTTPPVLD
Position: 399-408
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 59
Chemical type: Peptide from protein
Sequence: NYKTTPPVLDSD
Position: 399-410
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 98
Chemical type: Peptide from protein
Sequence: PENNYKTTPPVLD
Position: 396-408
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 60
Chemical type: Peptide from protein
Sequence: PENNYKTTPPVLDSD
Position: 396-410
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 87
Chemical type: Peptide from protein
Sequence: PEVKFNW
Position: 280-286
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 145
Chemical type: Peptide from protein
Sequence: PEVKFNWYV
Position: 280-288
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 17
Chemical type: Peptide from protein
Sequence: PEVKFNWYVD
Position: 280-289
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 39
Chemical type: Peptide from protein
Sequence: PEVKFNWYVDGVEVH
Position: 280-294
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 66
Chemical type: Peptide from protein
Sequence: PEVKFNWYVDGVEVHNAKTK
Position: 280-299
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 142
Chemical type: Peptide from protein
Sequence: PEVKFNWYVDGVEVHNAKTKPR
Position: 280-301
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 134
Chemical type: Peptide from protein
Sequence: PEVKFNWYVDGVEVHNAKTKPRE
Position: 280-302
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 100
Chemical type: Peptide from protein
Sequence: PEVKFNWYVDGVEVHNAKTKPREE
Position: 280-303
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 52
Chemical type: Peptide from protein
Sequence: PEVQFNWYVD
Position: 150-159
Source molecule (GenBank): 1463807526
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 32
Chemical type: Peptide from protein
Sequence: PEVQFNWYVDGVEVHNAKTK
Position: 150-169
Source molecule (GenBank): 1463807526
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 101
Chemical type: Peptide from protein
Sequence: PEVQFNWYVDGVEVHNAKTKPRE
Position: 150-172
Source molecule (GenBank): 1463807526
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 102
Chemical type: Peptide from protein
Sequence: PEVQFNWYVDGVEVHNAKTKPREE
Position: 150-173
Source molecule (GenBank): 1463807526
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 59
Chemical type: Peptide from protein
Sequence: PEVQFNWYVDGVEVHNAKTKPREEQ
Position: 150-174
Source molecule (GenBank): 1463807526
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 132
Chemical type: Peptide from protein
Sequence: PGQPASISCRSSRS
Position: 15-28
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 180
Chemical type: Peptide from protein
Sequence: PREAKVQWKVDNALQSGNSQESVTEQDSKD
Position: 146-175
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 95
Chemical type: Peptide from protein
Sequence: PSVFLFPPKPKD
Position: 247-258
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 104
Chemical type: Peptide from protein
Sequence: PVTVSWNSGALTSGVH
Position: 175-190
Source molecule (GenBank): QBK47431.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 33
Chemical type: Peptide from protein
Sequence: QAPRLLIYGASSR
Position: 43-55
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 26
Chemical type: Peptide from protein
Sequence: QAPRLLIYGASSRA
Position: 43-56
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 50
Chemical type: Peptide from protein
Sequence: QAPRLLIYGASSRAT
Position: 43-57
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 51
Chemical type: Peptide from protein
Sequence: QAPRLLIYGASSRATG
Position: 43-58
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 52
Chemical type: Peptide from protein
Sequence: QAPRLLIYGASSRATGIPD
Position: 43-61
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 153
Chemical type: Peptide from protein
Sequence: QDSKDSTYSLSSTLTLSKA
Position: 171-189
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 91
Chemical type: Peptide from protein
Sequence: QGTLVTVSSASTKGPSVFPL
Position: 131-150
Source molecule (GenBank): QBK47431.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 91
Chemical type: Peptide from protein
Sequence: QKPGQAPRLLIYGASSRATG
Position: 39-58
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 45
Chemical type: Peptide from protein
Sequence: QSGNSQESVTEQDSKD
Position: 156-171
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 134
Chemical type: Peptide from protein
Sequence: QSPQLLIYKVSNRFI
Position: 47-61
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 48
Chemical type: Peptide from protein
Sequence: QSPQLLIYKVSNRFIG
Position: 47-62
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 31
Chemical type: Peptide from protein
Sequence: QVQLVQSGAEVKK
Position: 20-32
Source molecule (GenBank): QBK47431.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 20
Chemical type: Peptide from protein
Sequence: QVQLVQSGAEVKKPG
Position: 20-34
Source molecule (GenBank): QBK47431.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 47
Chemical type: Peptide from protein
Sequence: QVQLVQSGAEVKKPGS
Position: 1-16
Source molecule (GenBank): 21669745
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 71
Chemical type: Peptide from protein
Sequence: QVQLVQSGAEVKKPGSSVKV
Position: 1-20
Source molecule (GenBank): 21669745
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 122
Chemical type: Peptide from protein
Sequence: RDNAKNSLYLQMNSLRVEDT
Position: 72-91
Source molecule (GenBank): 62871008
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 91
Chemical type: Peptide from protein
Sequence: RDNAKNSLYLQMNSLRVEDTA
Position: 58-78
Source molecule (GenBank): 4456588
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 157
Chemical type: Peptide from protein
Sequence: RFSGSGSGTDFTLKISRVEAE
Position: 66-86
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 56
Chemical type: Peptide from protein
Sequence: RFSGSGSGTDFTLKISRVEAED
Position: 66-87
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 107
Chemical type: Peptide from protein
Sequence: RFSGSGSGTDFTLTISRLEPED
Position: 62-83
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 132
Chemical type: Peptide from protein
Sequence: RGTLVTVSSA
Position: 113-122
Source molecule (GenBank): 8250273
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 125
Chemical type: Peptide from protein
Sequence: RTPEVTCVVVDVSHED
Position: 264-279
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 52
Chemical type: Peptide from protein
Sequence: RTPEVTCVVVDVSHEDPE
Position: 264-281
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 21
Chemical type: Peptide from protein
Sequence: RTPEVTCVVVDVSQEDPE
Position: 25-42
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 107
Chemical type: Peptide from protein
Sequence: RVVSVLTVLHQD
Position: 323-334
Source molecule (GenBank): QBK47431.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 44
Chemical type: Peptide from protein
Sequence: SDGSFFLYSKLTVDKSR
Position: 409-425
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 89
Chemical type: Peptide from protein
Sequence: SDGSFFLYSRLTVDKS
Position: 342-357
Source molecule (GenBank): 9857759
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 24
Chemical type: Peptide from protein
Sequence: SDGSFFLYSRLTVDKSR
Position: 315-331
Source molecule (GenBank): 10334595
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 90
Chemical type: Peptide from protein
Sequence: SDGSFFLYSRLTVDKSRW
Position: 315-332
Source molecule (GenBank): 10334595
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 49
Chemical type: Peptide from protein
Sequence: SDGSFFLYSRLTVDKSRWQ
Position: 315-333
Source molecule (GenBank): 10334595
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 108
Chemical type: Peptide from protein
Sequence: SFFLYSRLTVDKSR
Position: 318-331
Source molecule (GenBank): 10334595
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 81
Chemical type: Peptide from protein
Sequence: SFFLYSRLTVDKSRWQ
Position: 318-333
Source molecule (GenBank): 10334595
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 82
Chemical type: Peptide from protein
Sequence: SFFLYSRLTVDKSRWQE
Position: 318-334
Source molecule (GenBank): 10334595
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 76
Chemical type: Peptide from protein
Sequence: SFTDYHIHWVRQAPG
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 77
Chemical type: Peptide from protein
Sequence: SFTDYHIHWVRQAPGQG
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 12
Chemical type: Peptide from protein
Sequence: SGNSQESVTEQDSKD
Position: 157-171
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 171
Chemical type: Peptide from protein
Sequence: SGSGSGTDFTLKISRVEAED
Position: 68-87
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 87
Chemical type: Peptide from protein
Sequence: SGSGTDFTLKISRVEAED
Position: 70-87
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 117
Chemical type: Peptide from protein
Sequence: SGTDFTLKISRVEA
Position: 72-85
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 88
Chemical type: Peptide from protein
Sequence: SGTDFTLKISRVEAE
Position: 72-86
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 61
Chemical type: Peptide from protein
Sequence: SGTDFTLKISRVEAED
Position: 15-30
Source molecule (GenBank): CAC94636.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 136
Chemical type: Peptide from protein
Sequence: SGTDFTLKISRVEAEDVG
Position: 72-89
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 64
Chemical type: Peptide from protein
Sequence: SGTDFTLTISRLEPE
Position: 68-82
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 74
Chemical type: Peptide from protein
Sequence: SGTDFTLTISRLEPED
Position: 68-83
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 101
Chemical type: Peptide from protein
Sequence: SGTDFTLTISRLEPEDF
Position: 68-84
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 104
Chemical type: Peptide from protein
Sequence: SGVHTFPAVLQSSG
Position: 174-187
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 66
Chemical type: Peptide from protein
Sequence: SIEKTISKAKGQPR
Position: 101-114
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 43
Chemical type: Peptide from protein
Sequence: SIEKTISKAKGQPREPQ
Position: 101-117
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 87
Chemical type: Peptide from protein
Sequence: SKADYEKHKVYACEVT
Position: 183-198
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 88
Chemical type: Peptide from protein
Sequence: SKADYEKHKVYACEVTH
Position: 183-199
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 181
Chemical type: Peptide from protein
Sequence: SKDSTYSLSSTLTL
Position: 173-186
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 35
Chemical type: Peptide from protein
Sequence: SKDSTYSLSSTLTLSKA
Position: 169-185
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 10
Chemical type: Peptide from protein
Sequence: SKDSTYSLSSTLTLSKAD
Position: 169-186
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 158
Chemical type: Peptide from protein
Sequence: SKDSTYSLSSTLTLSKADY
Position: 173-191
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 159
Chemical type: Peptide from protein
Sequence: SKDSTYSLSSTLTLSKADYE
Position: 173-192
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 160
Chemical type: Peptide from protein
Sequence: SKDSTYSLSSTLTLSKADYEK
Position: 173-193
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 67
Chemical type: Peptide from protein
Sequence: SKDSTYSLSSTLTLSKADYEKH
Position: 169-190
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 161
Chemical type: Peptide from protein
Sequence: SKDSTYSLSSTLTLSKADYEKHK
Position: 173-195
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 81
Chemical type: Peptide from protein
Sequence: SKDSTYSLSSTLTLSKADYEKHKV
Position: 169-192
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 162
Chemical type: Peptide from protein
Sequence: SKDSTYSLSSTLTLSKADYEKHKVY
Position: 173-197
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 163
Chemical type: Peptide from protein
Sequence: SKDSTYSLSSTLTLSKADYEKHKVYA
Position: 173-198
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 74
Chemical type: Peptide from protein
Sequence: SLVHSRGNTYLHWYLQKPGQSPQ
Position: 28-50
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 75
Chemical type: Peptide from protein
Sequence: SLVHSRGNTYLHWYLQKPGQSPQLL
Position: 28-52
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 110
Chemical type: Peptide from protein
Sequence: SLYLQMNSLRVED
Position: 64-76
Source molecule (GenBank): 4456588
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 80
Chemical type: Peptide from protein
Sequence: SLYLQMNSLRVEDT
Position: 48-61
Source molecule (GenBank): 1360487213
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 106
Chemical type: Peptide from protein
Sequence: SLYLQMNSLRVEDTA
Position: 64-78
Source molecule (GenBank): 4456588
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 78
Chemical type: Peptide from protein
Sequence: SNGQPENNYKTTPPVLD
Position: 392-408
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 89
Chemical type: Peptide from protein
Sequence: SNGQPENNYKTTPPVLDSD
Position: 392-410
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 93
Chemical type: Peptide from protein
Sequence: SPGERATLSCRASQS
Position: 14-28
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 94
Chemical type: Peptide from protein
Sequence: SPGERATLSCRASQSVS
Position: 14-30
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 13
Chemical type: Peptide from protein
Sequence: SPQLLIYKVSNRFIG
Position: 48-62
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 15
Chemical type: Peptide from protein
Sequence: SPQLLIYKVSNRFIGVPD
Position: 48-65
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 27
Chemical type: Peptide from protein
Sequence: SPQLLIYKVSNRFIGVPDR
Position: 48-66
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 102
Chemical type: Peptide from protein
Sequence: SPQLLIYKVSNRFIGVPDRF
Position: 48-67
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 178
Chemical type: Peptide from protein
Sequence: SQESVTEQDSKDSTYSLSSTLTLSKAD
Position: 164-190
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 70
Chemical type: Peptide from protein
Sequence: SRGNTYLHWYLQKPGQSPQ
Position: 32-50
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 122
Chemical type: Peptide from protein
Sequence: SRGNTYLHWYLQKPGQSPQL
Position: 32-51
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 123
Chemical type: Peptide from protein
Sequence: SRGNTYLHWYLQKPGQSPQLL
Position: 32-52
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 124
Chemical type: Peptide from protein
Sequence: SRGNTYLHWYLQKPGQSPQLLI
Position: 32-53
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 56
Chemical type: Peptide from protein
Sequence: SSIEKTISKAKGQPREPQ
Position: 100-117
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 116
Chemical type: Peptide from protein
Sequence: SSPVTKSFNRGEC
Position: 203-215
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: IXE36
Chemical type: Peptide from protein
Sequence: SSRSLVHSRGNTY
Position: 169-181
Source molecule (GenBank): 6NOU_A
Assay category: TCell
Result: Positive
MHC allele types: 354 425 419 413
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: IXE36
Chemical type: Peptide from protein
Sequence: SSRSLVHSRGNTY
Position: 169-181
Source molecule (GenBank): 6NOU_A
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 79
Chemical type: Peptide from protein
Sequence: STAYMELSSLRSED
Position: 77-90
Source molecule (GenBank): 21669745
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 40
Chemical type: Peptide from protein
Sequence: STAYMELSSLRSEDT
Position: 77-91
Source molecule (GenBank): 21669745
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 85
Chemical type: Peptide from protein
Sequence: STAYMELSSLRSEDTA
Position: 77-92
Source molecule (GenBank): 21669745
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 62
Chemical type: Peptide from protein
Sequence: STSTAYMELSSLRSEDTA
Position: 75-92
Source molecule (GenBank): 21669745
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 164
Chemical type: Peptide from protein
Sequence: STYSLSSTLTLSK
Position: 176-188
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 108
Chemical type: Peptide from protein
Sequence: STYSLSSTLTLSKA
Position: 172-185
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 165
Chemical type: Peptide from protein
Sequence: STYSLSSTLTLSKADYE
Position: 176-192
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 166
Chemical type: Peptide from protein
Sequence: STYSLSSTLTLSKADYEK
Position: 176-193
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 167
Chemical type: Peptide from protein
Sequence: STYSLSSTLTLSKADYEKHK
Position: 176-195
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 110
Chemical type: Peptide from protein
Sequence: STYSLSSTLTLSKADYEKHKV
Position: 172-192
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 168
Chemical type: Peptide from protein
Sequence: STYSLSSTLTLSKADYEKHKVY
Position: 176-197
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 41
Chemical type: Peptide from protein
Sequence: STYSLSSTLTLSKADYEKHKVYA
Position: 176-198
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 28
Chemical type: Peptide from protein
Sequence: SVMHEALHNHYTQKSLSLSLG
Position: 196-216
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 34
Chemical type: Peptide from protein
Sequence: SVMHEALHNHYTQKSLSLSPG
Position: 435-455
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 138
Chemical type: Peptide from protein
Sequence: SVMHEALHNHYTQKSLSLSPGK
Position: 435-456
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 135
Chemical type: Peptide from protein
Sequence: SVTPGQPASISCRSSRSL
Position: 12-29
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 147
Chemical type: Peptide from protein
Sequence: TASVVCLLNNFYPR
Position: 134-147
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 84
Chemical type: Peptide from protein
Sequence: TASVVCLLNNFYPRE
Position: 130-144
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 42
Chemical type: Peptide from protein
Sequence: TAYMELSSLRSEDT
Position: 78-91
Source molecule (GenBank): 21669745
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 118
Chemical type: Peptide from protein
Sequence: TDFTLKISRVEAED
Position: 74-87
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 74
Chemical type: Peptide from protein
Sequence: TDYHIHWVRQAPG
Position: 30-42
Source molecule (GenBank): 1148301179
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 135
Chemical type: Peptide from protein
Sequence: TLMISRTPEVTCVVVDVSHED
Position: 259-279
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 86
Chemical type: Peptide from protein
Sequence: TPGQPASISCRSSRS
Position: 14-28
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 67
Chemical type: Peptide from protein
Sequence: TPGQPASISCRSSRSLVH
Position: 14-31
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 31
Chemical type: Peptide from protein
Sequence: TPGQPASISCRSSRSLVHSR
Position: 14-33
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 9
Chemical type: Peptide from protein
Sequence: TQKSLSLSLG
Position: 207-216
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 13
Chemical type: Peptide from protein
Sequence: TQKSLSLSPG
Position: 446-455
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 27
Chemical type: Peptide from protein
Sequence: TQKSLSLSPGK
Position: 446-456
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 120
Chemical type: Peptide from protein
Sequence: TQTYICNVNHKPSNTKVDKRVEPK
Position: 204-227
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 78
Chemical type: Peptide from protein
Sequence: TSGVHTFPAVLQS
Position: 186-198
Source molecule (GenBank): QBK47431.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 33
Chemical type: Peptide from protein
Sequence: TSTAYMELSSLRSED
Position: 76-90
Source molecule (GenBank): 21669745
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 11
Chemical type: Peptide from protein
Sequence: TSTAYMELSSLRSEDT
Position: 76-91
Source molecule (GenBank): 21669745
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 12
Chemical type: Peptide from protein
Sequence: TSTAYMELSSLRSEDTA
Position: 76-92
Source molecule (GenBank): 21669745
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 72
Chemical type: Peptide from protein
Sequence: TYLHWYLQKPGQSPQL
Position: 36-51
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 127
Chemical type: Peptide from protein
Sequence: TYLHWYLQKPGQSPQLLI
Position: 36-53
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 84
Chemical type: Peptide from protein
Sequence: VAAINQDGSEKYYVG
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 128
Chemical type: Peptide from protein
Sequence: VDGVEVHNAKTKPREEQ
Position: 288-304
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 94
Chemical type: Peptide from protein
Sequence: VDKSRWQEGNVFSCSVMHEALHNH
Position: 79-102
Source molecule (GenBank): 223060
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 99
Chemical type: Peptide from protein
Sequence: VDNALQSGNSQESVTEQ
Position: 151-167
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 115
Chemical type: Peptide from protein
Sequence: VDNALQSGNSQESVTEQDSKD
Position: 151-171
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab P 117
Chemical type: Peptide from protein
Sequence: VEWESNGQPENNYK
Position: 388-401
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 99
Chemical type: Peptide from protein
Sequence: VGVYYCSQSTHLPFT
Position: 88-102
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 125
Chemical type: Peptide from protein
Sequence: VHSRGNTYLHWYLQKPGQSPQ
Position: 30-50
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 126
Chemical type: Peptide from protein
Sequence: VHSRGNTYLHWYLQKPGQSPQLL
Position: 30-52
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 64
Chemical type: Peptide from protein
Sequence: VKDYFPEPVTVSWNSG
Position: 168-183
Source molecule (GenBank): QBK47431.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 141
Chemical type: Peptide from protein
Sequence: VKGRFTISRDNAKNSL
Position: 31-46
Source molecule (GenBank): 26801144
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 18
Chemical type: Peptide from protein
Sequence: VMHEALHNHYTQKSLSLSLG
Position: 197-216
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 12
Chemical type: Peptide from protein
Sequence: VMHEALHNHYTQKSLSLSPG
Position: 436-455
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 42
Chemical type: Peptide from protein
Sequence: VPDRFSGSGSGTD
Position: 63-75
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 105
Chemical type: Peptide from protein
Sequence: VPSSSLGTQTYICNVNHKPSN
Position: 197-217
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 112
Chemical type: Peptide from protein
Sequence: VRQAPGKGLE
Position: 37-46
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 101
Chemical type: Peptide from protein
Sequence: VSHEDPEVKFN
Position: 275-285
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 103
Chemical type: Peptide from protein
Sequence: VSHEDPEVKFNWYVD
Position: 275-289
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 18
Chemical type: Peptide from protein
Sequence: VTPGQPASISCRSSR
Position: 13-27
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 131
Chemical type: Peptide from protein
Sequence: VTPGQPASISCRSSRS
Position: 13-28
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: IXE35
Chemical type: Peptide from protein
Sequence: VTPGQPASISCRSSRSL
Position: 157-173
Source molecule (GenBank): 6NOU_A
Assay category: TCell
Result: Positive
MHC allele types: 419 57
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: IXE35
Chemical type: Peptide from protein
Sequence: VTPGQPASISCRSSRSL
Position: 157-173
Source molecule (GenBank): 6NOU_A
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 74
Chemical type: Peptide from protein
Sequence: VVVDVSHED
Position: 271-279
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 19
Chemical type: Peptide from protein
Sequence: WGRGTLVTVSSA
Position: 111-122
Source molecule (GenBank): 8250273
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 50
Chemical type: Peptide from protein
Sequence: WGRGTLVTVSSASTKGPSVFPLAPSSK
Position: 116-142
Source molecule (GenBank): 323432279
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 82
Chemical type: Peptide from protein
Sequence: WVAAINQDGSEKYYVG
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 93
Chemical type: Peptide from protein
Sequence: WVAAINQDGSEKYYVGS
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 127
Chemical type: Peptide from protein
Sequence: WVAAINQDGSEKYYVGSV
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 83
Chemical type: Peptide from protein
Sequence: WVAAINQDGSEKYYVGSVK
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 65
Chemical type: Peptide from protein
Sequence: WYFDLWGRGTLVTVSSASTKGPSVFPLAPSSK
Position: 94-125
Source molecule (GenBank): 86438950
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 69
Chemical type: Peptide from protein
Sequence: YEKHKVYACEVTH
Position: 187-199
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 83
Chemical type: Peptide from protein
Sequence: YEKHKVYACEVTHQG
Position: 187-201
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 98
Chemical type: Peptide from protein
Sequence: YEKHKVYACEVTHQGLSSPV
Position: 187-206
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 49
Chemical type: Peptide from protein
Sequence: YEKHKVYACEVTHQGLSSPVTKSFNRGEC
Position: 187-215
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 28
Chemical type: Peptide from protein
Sequence: YFDLWGRGTLVTVSS
Position: 127-141
Source molecule (GenBank): 346139
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 14
Chemical type: Peptide from protein
Sequence: YFDLWGRGTLVTVSSA
Position: 107-122
Source molecule (GenBank): 8250273
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 111
Chemical type: Peptide from protein
Sequence: YFDLWGRGTLVTVSSASTKGPSVFPLAPSS
Position: 95-124
Source molecule (GenBank): 86438950
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 32
Chemical type: Peptide from protein
Sequence: YFDLWGRGTLVTVSSASTKGPSVFPLAPSSK
Position: 95-125
Source molecule (GenBank): 86438950
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 131
Chemical type: Peptide from protein
Sequence: YFDLWGRGTLVTVSSASTKGPSVFPLAPSSKS
Position: 95-126
Source molecule (GenBank): 86438950
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 115
Chemical type: Peptide from protein
Sequence: YHIHWVRQAPG
Position: 32-42
Source molecule (GenBank): 21670675
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 67
Chemical type: Peptide from protein
Sequence: YHIHWVRQAPGQGLE
Position: 32-46
Source molecule (GenBank): 21670675
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 117
Chemical type: Peptide from protein
Sequence: YKTTPPVLD
Position: 413-421
Source molecule (GenBank): QBK47431.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 53
Chemical type: Peptide from protein
Sequence: YKTTPPVLDSD
Position: 413-423
Source molecule (GenBank): QBK47431.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 76
Chemical type: Peptide from protein
Sequence: YLHWYLQKPGQSPQ
Position: 37-50
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 109
Chemical type: Peptide from protein
Sequence: YLHWYLQKPGQSPQL
Position: 37-51
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 107
Chemical type: Peptide from protein
Sequence: YLQMNSLRVEDT
Position: 66-77
Source molecule (GenBank): 4456588
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 129
Chemical type: Peptide from protein
Sequence: YLQMNSLRVEDTA
Position: 66-78
Source molecule (GenBank): 4456588
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 73
Chemical type: Peptide from protein
Sequence: YPREAKVQWKVDNALQSGNS
Position: 141-160
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab light P 79
Chemical type: Peptide from protein
Sequence: YPREAKVQWKVDNALQSGNSQ
Position: 141-161
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 172
Chemical type: Peptide from protein
Sequence: YPREAKVQWKVDNALQSGNSQESVTEQD
Position: 145-172
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 173
Chemical type: Peptide from protein
Sequence: YPREAKVQWKVDNALQSGNSQESVTEQDSKD
Position: 145-175
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab/ixekizumab heavy P 48
Chemical type: Peptide from protein
Sequence: YPSDIAVEWESNGQPENNYK
Position: 382-401
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab light P 38
Chemical type: Peptide from protein
Sequence: YQQKPGQAPRLLIYGASSRATGIPD
Position: 37-61
Source molecule (GenBank): BAF64541.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 110
Chemical type: Peptide from protein
Sequence: YSRLTVDKSR
Position: 322-331
Source molecule (GenBank): 10334595
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab heavy P 6
Chemical type: Peptide from protein
Sequence: YTQKSLSLSLG
Position: 206-216
Source molecule (GenBank): 2414494
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 11
Chemical type: Peptide from protein
Sequence: YTQKSLSLSPG
Position: 445-455
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 21
Chemical type: Peptide from protein
Sequence: YTQKSLSLSPGK
Position: 445-456
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Secukinumab heavy P 137
Chemical type: Peptide from protein
Sequence: YVDGVEVHNAKTKPREEQ
Position: 287-304
Source molecule (GenBank): ARA90391.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Ixekizumab light P 183
Chemical type: Peptide from protein
Sequence: RFSGSGSGTD
Position: 66-75
Source molecule (GenBank): 6NOV_B
Assay category: MhcLigandElution
Result: Positive

Epitope: IXE12
Chemical type: Peptide from protein
Sequence: EDTAVYYCARYDYFTGTGVY
Position: 89-108
Source molecule (GenBank): 6NOU_A
Assay category: TCell
Result: Positive
MHC allele types: 63 413 53 419 54
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: IXE13
Chemical type: Peptide from protein
Sequence: ARYDYFTGTGVYWGQGTLVT
Position: 97-116
Source molecule (GenBank): 6NOU_A
Assay category: TCell
Result: Positive
MHC allele types: 63 413 53 419 54
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: IXE15
Chemical type: Peptide from protein
Sequence: TLVTVSSASTKGPSVFPLAP
Position: 133-152
Source molecule (GenBank): QBK47431.1
Assay category: TCell
Result: Positive
MHC allele types: 53 413 419 63
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: IXE37
Chemical type: Peptide from protein
Sequence: SLVHSRGNTYLHWYLQ
Position: 172-187
Source molecule (GenBank): 6NOU_A
Assay category: TCell
Result: Positive
MHC allele types: 354 425 419 57 413
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: IXE18
Chemical type: Peptide from protein
Sequence: QPASISCRSSRSLVHSRGNT
Position: 161-180
Source molecule (GenBank): 6NOU_A
Assay category: TCell
Result: Positive
MHC allele types: 419 413
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: IXE19
Chemical type: Peptide from protein
Sequence: SSRSLVHSRGNTYLHWYLQK
Position: 169-188
Source molecule (GenBank): 6NOU_A
Assay category: TCell
Result: Positive
MHC allele types: 419 413 425 436
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: IXE27
Chemical type: Peptide from protein
Sequence: GVYYCSQSTHLPFTFGQGTK
Position: 89-108
Source molecule (GenBank): 6NOV_B
Assay category: TCell
Result: Positive
MHC allele types: 419 413 425 436
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone