Reference: P A Wentworth; A Sette; E Celis; J Sidney; S Southwood; C Crimi; S Stitely; E Keogh; N C Wong; B Livingston; D Alazard; A Vitiello; H M Grey; F V Chisari; R W Chesnut; J Fikes. "Identification of A2-restricted hepatitis C virus-specific cytotoxic T lymphocyte epitopes from conserved regions of the viral genome." International immunology (1996).

Epitope: NS1/E2 684-692
Chemical type: Peptide from protein
Sequence: ALSTGLIHL
Position: 684-692
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS1/E2 684-692
Chemical type: Peptide from protein
Sequence: ALSTGLIHL
Position: 684-692
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 313.0

Epitope: NS3 1183-1191
Chemical type: Peptide from protein
Sequence: AVCTRGVAK
Position: 1183-1191
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 385.0

Epitope: NS3 1183-1191
Chemical type: Peptide from protein
Sequence: AVCTRGVAK
Position: 1183-1191
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 240.0

Epitope: NS3 1123-1131
Chemical type: Peptide from protein
Sequence: CTCGSSDLY
Position: 1123-1131
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 108.0

Epitope: Core 132-140
Chemical type: Peptide from protein
Sequence: DLMGYIPLV
Position: 132-140
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 132-140
Chemical type: Peptide from protein
Sequence: DLMGYIPLV
Position: 132-140
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: Core 132-140
Chemical type: Peptide from protein
Sequence: DLMGYIPLV
Position: 132-140
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Core 132-140
Chemical type: Peptide from protein
Sequence: DLMGYIPLV
Position: 132-140
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 80.0

Epitope: NS5 2563-2571
Chemical type: Peptide from protein
Sequence: EVFCVQPEK
Position: 2562-2570
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 220.0

Epitope: NS1/E2 723-731
Chemical type: Peptide from protein
Sequence: FLLLADARV
Position: 723-731
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS1/E2 723-731
Chemical type: Peptide from protein
Sequence: FLLLADARV
Position: 723-731
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: NS1/E2 723-731
Chemical type: Peptide from protein
Sequence: FLLLADARV
Position: 723-731
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 18.0

Epitope: NS4 1858-1867
Chemical type: Peptide from protein
Sequence: GVAGALVAFK
Position: 1858-1867
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 4.0

Epitope: NS4 1858-1867
Chemical type: Peptide from protein
Sequence: GVAGALVAFK
Position: 1858-1867
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 26.0

Epitope: NS3 1227-1236
Chemical type: Peptide from protein
Sequence: HLHAPTGSGK
Position: 1227-1236
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 17.0

Epitope: NS3 1390-1398
Chemical type: Peptide from protein
Sequence: HLIFCHSKK
Position: 1390-1398
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 400.0

Epitope: NS3 1390-1399
Chemical type: Peptide from protein
Sequence: HLIFCHSKKK
Position: 1390-1399
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 385.0

Epitope: NS4 1769-1777
Chemical type: Peptide from protein
Sequence: HMWNFISGI
Position: 1764-1772
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4 1769-1777
Chemical type: Peptide from protein
Sequence: HMWNFISGI
Position: 1764-1772
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: NS4 1769-1777
Chemical type: Peptide from protein
Sequence: HMWNFISGI
Position: 1764-1772
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 15.0

Epitope: NS4 1851-1859
Chemical type: Peptide from protein
Sequence: ILAGYGAGV
Position: 1851-1859
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: NS4 1851-1859
Chemical type: Peptide from protein
Sequence: ILAGYGAGV
Position: 1851-1859
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4 1851-1859
Chemical type: Peptide from protein
Sequence: ILAGYGAGV
Position: 1851-1859
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 116.0

Epitope: NS4 1811-1820
Chemical type: Peptide from protein
Sequence: ILGGWVAAQL
Position: 1811-1820
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4 1811-1820
Chemical type: Peptide from protein
Sequence: ILGGWVAAQL
Position: 1811-1820
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: NS4 1811-1820
Chemical type: Peptide from protein
Sequence: ILGGWVAAQL
Position: 1811-1820
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 116.0

Epitope: NS4 1807-1816
Chemical type: Peptide from protein
Sequence: LLFNILGGWV
Position: 1807-1816
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4 1807-1816
Chemical type: Peptide from protein
Sequence: LLFNILGGWV
Position: 1807-1816
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: NS4 1807-1816
Chemical type: Peptide from protein
Sequence: LLFNILGGWV
Position: 1807-1816
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4 1807-1816
Chemical type: Peptide from protein
Sequence: LLFNILGGWV
Position: 1807-1816
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 4.0

Epitope: NS5 2879-2887
Chemical type: Peptide from protein
Sequence: LSAFSLHSY
Position: 2888-2896
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 49.0

Epitope: NS1/E2 631-640
Chemical type: Peptide from protein
Sequence: MYVGGVEHRL
Position: 631-640
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 259.0

Epitope: NS4 1773-1781
Chemical type: Peptide from protein
Sequence: QYLAGLSTL
Position: 1773-1781
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 146.0

Epitope: NS5 2885-2894
Chemical type: Peptide from protein
Sequence: RLHGLSAFSL
Position: 2884-2893
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5 2885-2894
Chemical type: Peptide from protein
Sequence: RLHGLSAFSL
Position: 2884-2893
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 179.0

Epitope: NS5 2578-2587
Chemical type: Peptide from protein
Sequence: RLIVFPDLGV
Position: 2577-2586
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS5 2578-2587
Chemical type: Peptide from protein
Sequence: RLIVFPDLGV
Position: 2577-2586
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 56.0

Epitope: NS3 1029-1037
Chemical type: Peptide from protein
Sequence: RLLAPITAY
Position: 1024-1032
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 4.0

Epitope: NS5 2621-2629
Chemical type: Peptide from protein
Sequence: RVCEKMALY
Position: 2587-2595
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 56.0

Epitope: NS5 2269-2277
Chemical type: Peptide from protein
Sequence: SVPAEILRK
Position: 2269-2277
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 13.0

Epitope: NS3 1261-1270
Chemical type: Peptide from protein
Sequence: TLGFGAYMSK
Position: 1261-1270
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 124.0

Epitope: NS3 1617-1626
Chemical type: Peptide from protein
Sequence: TLHGPTPLLY
Position: 1617-1626
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 112.0

Epitope: NS4 1666-1675
Chemical type: Peptide from protein
Sequence: VLAALAAYCL
Position: 1666-1675
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4 1666-1675
Chemical type: Peptide from protein
Sequence: VLAALAAYCL
Position: 1666-1675
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: NS4 1666-1675
Chemical type: Peptide from protein
Sequence: VLAALAAYCL
Position: 1666-1675
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 100.0

Epitope: NS1/E2 557-656
Chemical type: Peptide from protein
Sequence: WMNSTGFTK
Position: 554-562
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 189.0

Epitope: core 35-44
Chemical type: Peptide from protein
Sequence: YLLPRRGPRL
Position: 35-44
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: core 35-44
Chemical type: Peptide from protein
Sequence: YLLPRRGPRL
Position: 35-44
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: core 35-44
Chemical type: Peptide from protein
Sequence: YLLPRRGPRL
Position: 35-44
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: core 35-44
Chemical type: Peptide from protein
Sequence: YLLPRRGPRL
Position: 35-44
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 125.0

Epitope: NS4 1585-1593
Chemical type: Peptide from protein
Sequence: YLVAYQATV
Position: 1585-1593
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS4 1585-1593
Chemical type: Peptide from protein
Sequence: YLVAYQATV
Position: 1585-1593
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: NS4 1585-1593
Chemical type: Peptide from protein
Sequence: YLVAYQATV
Position: 1585-1593
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 20.0

Epitope: NS3 1131-1139
Chemical type: Peptide from protein
Sequence: YLVTRHADV
Position: 1131-1139
Source molecule (GenBank): P26663.3
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS3 1131-1139
Chemical type: Peptide from protein
Sequence: YLVTRHADV
Position: 1131-1139
Source molecule (GenBank): P26663.3
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 575.0