Reference: Jan Petersen; Laura Ciacchi; Mai T Tran; Khai Lee Loh; Yvonne Kooy-Winkelaar; Nathan P Croft; Melinda Y Hardy; Zhenjun Chen; James McCluskey; Robert P Anderson; Anthony W Purcell; Jason A Tye-Din; Frits Koning; Hugh H Reid; Jamie Rossjohn. "T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease." Nature structural & molecular biology (2020).

Epitope: P.fluor-α1a
Chemical type: Peptide from protein
Sequence: PMPMPELPYP
Position: 275-284
Source molecule (GenBank): WP_134923046.1
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 200000.0

Epitope: P.fluor-α1a
Chemical type: Peptide from protein
Sequence: PMPMPELPYP
Position: 275-284
Source molecule (GenBank): WP_134923046.1
Assay category: TCell
Result: Positive
Quantitative measurement: 2.8

Epitope: P.fluor-α1a
Chemical type: Peptide from protein
Sequence: PMPMPELPYP
Position: 275-284
Source molecule (GenBank): WP_134923046.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: P.fluor-α1a
Chemical type: Peptide from protein
Sequence: PMPMPELPYP
Position: 275-284
Source molecule (GenBank): WP_134923046.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: P.fluor-α1a
Chemical type: Peptide from protein
Sequence: PMPMPELPYP
Position: 275-284
Source molecule (GenBank): WP_134923046.1
Assay category: TCell
Result: Positive
Quantitative measurement: 36900.0

Epitope: P.fluor-α1a
Chemical type: Peptide from protein
Sequence: PMPMPELPYP
Position: 275-284
Source molecule (GenBank): WP_134923046.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.8

Epitope: P.fluor-α1a
Chemical type: Peptide from protein
Sequence: PMPMPELPYP
Position: 275-284
Source molecule (GenBank): WP_134923046.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.9

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 200000.0

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 200000.0

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Quantitative measurement: 21400.0

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Quantitative measurement: 91500.0

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Quantitative measurement: 39600.0

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive-High
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α1
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPY
Position: 59-69
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α2
Chemical type: Peptide from protein
Sequence: FPQPQLPYPQP
Position: 62-72
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: DQ2.5-glia-α2
Chemical type: Peptide from protein
Sequence: FPQPQLPYPQP
Position: 62-72
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: DQ2.5-glia-α2
Chemical type: Peptide from protein
Sequence: FPQPQLPYPQP
Position: 62-72
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: DQ2.5-glia-α2
Chemical type: Peptide from protein
Sequence: FPQPQLPYPQP
Position: 62-72
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α2
Chemical type: Peptide from protein
Sequence: FPQPQLPYPQP
Position: 62-72
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α2
Chemical type: Peptide from protein
Sequence: FPQPQLPYPQP
Position: 62-72
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α2
Chemical type: Peptide from protein
Sequence: FPQPQLPYPQP
Position: 62-72
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α2
Chemical type: Peptide from protein
Sequence: FPQPQLPYPQP
Position: 62-72
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Quantitative measurement: 13500.0

Epitope: DQ2.5-glia-α2
Chemical type: Peptide from protein
Sequence: FPQPQLPYPQP
Position: 62-72
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α2
Chemical type: Peptide from protein
Sequence: FPQPQLPYPQP
Position: 62-72
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α2
Chemical type: Peptide from protein
Sequence: FPQPQLPYPQP
Position: 62-72
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α2
Chemical type: Peptide from protein
Sequence: FPQPQLPYPQP
Position: 62-72
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Quantitative measurement: 83700.0

Epitope: DQ2.5-glia-α2
Chemical type: Peptide from protein
Sequence: FPQPQLPYPQP
Position: 62-72
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α2
Chemical type: Peptide from protein
Sequence: FPQPQLPYPQP
Position: 62-72
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α2
Chemical type: Peptide from protein
Sequence: FPQPQLPYPQP
Position: 62-72
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: P.aerug-α2a-13mer
Chemical type: Peptide from protein
Sequence: MVVQSELPYPEGV
Position: 402-414
Source molecule (GenBank): WP_132802024.1
Assay category: TCell
Result: Positive
Host:  43-68 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P.aerug-α2a-13mer
Chemical type: Peptide from protein
Sequence: MVVQSELPYPEGV
Position: 402-414
Source molecule (GenBank): WP_132802024.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: P.fluor-α1b
Chemical type: Peptide from protein
Sequence: PMPLPDLPYP
Position: 275-284
Source molecule (GenBank): WP_214918363.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: P.fluor-α1b
Chemical type: Peptide from protein
Sequence: PMPLPDLPYP
Position: 275-284
Source molecule (GenBank): WP_214918363.1
Assay category: TCell
Result: Positive-High
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: P.fluor-α1b
Chemical type: Peptide from protein
Sequence: PMPLPDLPYP
Position: 275-284
Source molecule (GenBank): WP_214918363.1
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 200000.0

Epitope: A.baum-α1a
Chemical type: Peptide from protein
Sequence: VQPWPQPELPEY
Position: 395-406
Source molecule (GenBank): WP_005404987.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-ω1
Chemical type: Peptide from protein
Sequence: PFPQPQQPF
Position: 106-114
Source molecule (GenBank): Q9FUW7.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: P.fluor-α2a
Chemical type: Peptide from protein
Sequence: PMPELPYPAT
Position: 277-286
Source molecule (GenBank): WP_134923046.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: P.fluor-α2b
Chemical type: Peptide from protein
Sequence: PLPELPYPAT
Position: 283-292
Source molecule (GenBank): WP_034146782.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: B.copro-α2a
Chemical type: Peptide from protein
Sequence: LPLPDLPYPVA
Position: 92-102
Source molecule (GenBank): WP_008143626.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: IDGEPMPMPELPYPATP
Chemical type: Peptide from protein
Sequence: IDGEPMPMPELPYPATP
Position: 271-287
Source molecule (GenBank): WP_134923046.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P.fluor-α1/α2a-15mer
Chemical type: Peptide from protein
Sequence: GEPMPMPELPYPATP
Position: 273-287
Source molecule (GenBank): WP_134923046.1
Assay category: TCell
Result: Positive
Host:  43-68 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P.fluor-α1/α2a-15mer
Chemical type: Peptide from protein
Sequence: GEPMPMPELPYPATP
Position: 273-287
Source molecule (GenBank): WP_134923046.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: P.fluor-α1/α2a-15mer
Chemical type: Peptide from protein
Sequence: GEPMPMPELPYPATP
Position: 273-287
Source molecule (GenBank): WP_134923046.1
Assay category: MhcLigandElution
Result: Positive

Epitope: EPMPMPELPYPATP
Chemical type: Peptide from protein
Sequence: EPMPMPELPYPATP
Position: 274-287
Source molecule (GenBank): WP_134923046.1
Assay category: MhcLigandElution
Result: Positive

Epitope: PMPELPYPATP
Chemical type: Peptide from protein
Sequence: PMPELPYPATP
Position: 277-287
Source molecule (GenBank): WP_134923046.1
Assay category: MhcLigandElution
Result: Positive

Epitope: GEPmPmPELPYPATP
Chemical type: Peptide from protein
Sequence: GEPMPMPELPYPATP
Position: 273-287
Source molecule (GenBank): WP_134923046.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P.fluor-α1a-13mer
Chemical type: Peptide from protein
Sequence: GEPMPMPELPYPA
Position: 273-285
Source molecule (GenBank): WP_134923046.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: P.fluor-α2a-13mer
Chemical type: Peptide from protein
Sequence: PMPMPELPYPATP
Position: 275-287
Source molecule (GenBank): WP_134923046.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: B.copro-α2.2-13mer
Chemical type: Peptide from protein
Sequence: WLPLPDLPYPVAY
Position: 91-103
Source molecule (GenBank): WP_008143626.1
Assay category: TCell
Result: Positive
Host:  43-68 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: B.copro-α2.2-13mer
Chemical type: Peptide from protein
Sequence: WLPLPDLPYPVAY
Position: 91-103
Source molecule (GenBank): WP_008143626.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: P.fluor-α1/α2b-15mer
Chemical type: Peptide from protein
Sequence: GEPMPLPDLPYPATP
Position: 273-287
Source molecule (GenBank): WP_214918363.1
Assay category: TCell
Result: Positive
Host:  43-68 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P.fluor-α1/α2b-15mer
Chemical type: Peptide from protein
Sequence: GEPMPLPDLPYPATP
Position: 273-287
Source molecule (GenBank): WP_214918363.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Engineered

Epitope: DQ2.5-glia-α1a/α2-15mer
Chemical type: Peptide from protein
Sequence: LQPFPQPQLPYPQPQ
Position: 59-73
Source molecule (GenBank): Q9M4L6.1
Assay category: TCell
Result: Positive
Host:  43-68 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: DQ2.5-glia-ω1/ω2-15mer
Chemical type: Peptide from protein
Sequence: QPFPQPQQPFPWQP
Position: 105-118
Source molecule (GenBank): Q9FUW7.1
Assay category: TCell
Result: Positive
Host:  43-68 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo