Reference: Lance M Hellman; Kendra C Foley; Nishant K Singh; Jesus A Alonso; Timothy P Riley; Jason R Devlin; Cory M Ayres; Grant L J Keller; Yuting Zhang; Craig W Vander Kooi; Michael I Nishimura; Brian M Baker. "Improving T Cell Receptor On-Target Specificity via Structure-Guided Design." Molecular therapy : the journal of the American Society of Gene Therapy (2019).

Epitope: MART-1 (26-35; A2L) (10 mer)
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 43000.0

Epitope: MART-1 (26-35; A2L) (10 mer)
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: MART-1 (26-35; A2L) (10 mer)
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 36400.0

Epitope: MART-1 (26-35; A2L) (10 mer)
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 11000.0

Epitope: MART-1 (26-35; A2L) (10 mer)
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: MART-1 (26-35; A2L) (10 mer)
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 2.966

Epitope: MART-1 (26-35; A2L) (10 mer)
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: MART-1 (26-35; A2L) (10 mer)
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 61.2

Epitope: MART-1 (26-35; A2L) (10 mer)
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.347

Epitope: Mtub2
Chemical type: Peptide from protein
Sequence: IAGPGTITL
Position: 305-313
Source molecule (GenBank): AAA25361.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: hCD9
Chemical type: Peptide from protein
Sequence: AVGIGIAVV
Position: 198-206
Source molecule (GenBank): P21926.4
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: hCD9
Chemical type: Peptide from protein
Sequence: AVGIGIAVV
Position: 198-206
Source molecule (GenBank): P21926.4
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: hCD9
Chemical type: Peptide from protein
Sequence: AVGIGIAVV
Position: 198-206
Source molecule (GenBank): P21926.4
Assay category: TCell
Result: Positive-Low

Epitope: hCD9
Chemical type: Peptide from protein
Sequence: AVGIGIAVV
Position: 198-206
Source molecule (GenBank): P21926.4
Assay category: TCell
Result: Positive
Quantitative measurement: 22000.0

Epitope: hCD9
Chemical type: Peptide from protein
Sequence: AVGIGIAVV
Position: 198-206
Source molecule (GenBank): P21926.4
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 50.5

Epitope: HSV-2gpF
Chemical type: Peptide from protein
Sequence: GAGIGVAVL
Position: 447-455
Source molecule (GenBank): Q89730.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: ß-endoxylanase
Chemical type: Peptide from protein
Sequence: GAGIGVLTA
Position: 149-157
Source molecule (GenBank): WP_124065084.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: hEF1α
Chemical type: Peptide from protein
Sequence: IGGIGTVPV
Position: 256-264
Source molecule (GenBank): Q6IPT9.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: GPCR
Chemical type: Peptide from protein
Sequence: ALGLGLLPV
Position: 508-516
Source molecule (GenBank): WP_096634628.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: hREP1
Chemical type: Peptide from protein
Sequence: LGVIGLVAL
Position: 39-47
Source molecule (GenBank): Q00765.3
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: ADP
Chemical type: Peptide from protein
Sequence: VDGIGILTI
Position: 77-85
Source molecule (GenBank): Q01976.2
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: ADP
Chemical type: Peptide from protein
Sequence: VDGIGILTI
Position: 77-85
Source molecule (GenBank): Q01976.2
Assay category: TCell
Result: Positive-Low

Epitope: ADP
Chemical type: Peptide from protein
Sequence: VDGIGILTI
Position: 77-85
Source molecule (GenBank): Q01976.2
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: ADP
Chemical type: Peptide from protein
Sequence: VDGIGILTI
Position: 77-85
Source molecule (GenBank): Q01976.2
Assay category: TCell
Result: Positive
Quantitative measurement: 58000.0

Epitope: ADP
Chemical type: Peptide from protein
Sequence: VDGIGILTI
Position: 77-85
Source molecule (GenBank): Q01976.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 56.1

Epitope: ImrA
Chemical type: Peptide from protein
Sequence: LAGIGLIAA
Position: 12-20
Source molecule (GenBank): WP_085594716.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: Mtub1
Chemical type: Peptide from protein
Sequence: LGGLGLFFA
Position: 1773-1781
Source molecule (GenBank): Q02251.2
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: Mtub1
Chemical type: Peptide from protein
Sequence: LGGLGLFFA
Position: 1773-1781
Source molecule (GenBank): Q02251.2
Assay category: TCell
Result: Positive-Low

Epitope: Mtub1
Chemical type: Peptide from protein
Sequence: LGGLGLFFA
Position: 1773-1781
Source molecule (GenBank): Q02251.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Engineered

Epitope: Mtub1
Chemical type: Peptide from protein
Sequence: LGGLGLFFA
Position: 1773-1781
Source molecule (GenBank): Q02251.2
Assay category: TCell
Result: Positive
Quantitative measurement: 50000.0

Epitope: Mtub1
Chemical type: Peptide from protein
Sequence: LGGLGLFFA
Position: 1773-1781
Source molecule (GenBank): Q02251.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 50.5

Epitope: NLS
Chemical type: Peptide, no natural source
Sequence: NLSNLGILPV
Assay category: TCell
Result: Positive
Quantitative measurement: 12000.0

Epitope: NLS
Chemical type: Peptide, no natural source
Sequence: NLSNLGILPV
Assay category: TCell
Result: Positive
Quantitative measurement: 10000.0

Epitope: SLA
Chemical type: Peptide, no natural source
Sequence: SLANIGILPV
Assay category: TCell
Result: Positive
Quantitative measurement: 33000.0

Epitope: SLA
Chemical type: Peptide, no natural source
Sequence: SLANIGILPV
Assay category: TCell
Result: Positive
Quantitative measurement: 16000.0

Epitope: MMW
Chemical type: Peptide, no natural source
Sequence: MMWDRGLGMM
Assay category: TCell
Result: Positive
Quantitative measurement: 35000.0

Epitope: MMW
Chemical type: Peptide, no natural source
Sequence: MMWDRGLGMM
Assay category: TCell
Result: Positive
Quantitative measurement: 13000.0

Epitope: MMW
Chemical type: Peptide, no natural source
Sequence: MMWDRGLGMM
Assay category: TCell
Result: Positive
Quantitative measurement: 97600.0