Reference: Yongfeng Fan; Jianbo Dong; Jianlong Lou; Weihua Wen; Fraser Conrad; Isin N Geren; Consuelo Garcia-Rodriguez; Theresa J Smith; Leonard A Smith; Mengfei Ho; Melissa Pires-Alves; Brenda A Wilson; James D Marks. "Monoclonal Antibodies that Inhibit the Proteolytic Activity of Botulinum Neurotoxin Serotype/B." Toxins (2015).

Epitope: Epitope of mAb 16B3 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: G120, D121, Q178, N179, H180, R184, G186, I190
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of mAb 16B3 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: G120, D121, Q178, N179, H180, R184, G186, I190
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.84
Host: F

Epitope: Epitope of mAb 18E5 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: Y118, G120, R122, R123, I133, A134, Q178, H180
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive
Quantitative measurement: 1.0
Host: F

Epitope: Epitope of mAb 18E5 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: Y118, G120, R122, R123, I133, A134, Q178, H180
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of mAb 18A7, 18D10 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: R32, P56
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive
Quantitative measurement: 7.53
Host: F

Epitope: Epitope of mAb 18A7, 18D10 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: R32, P56
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive-Intermediate
Host: F

Epitope: Epitope of mAb 18A7, 18D10 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: R32, P56
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive
Quantitative measurement: 13.5
Host: F

Epitope: Epitope of mAb 18A7, 18D10 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: R32, P56
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of mAb 18A6 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: N304, L307, V308, K321, D333, E335, K337, S339
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Negative
Host: F

Epitope: Epitope of mAb 18A6 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: N304, L307, V308, K321, D333, E335, K337, S339
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive
Quantitative measurement: 4.21
Host: F

Epitope: Epitope of mAb 31A5 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: P125, A134, V136, G186, G189, H237, I310
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of mAb 31A5 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: P125, A134, V136, G186, G189, H237, I310
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive
Quantitative measurement: 1.75
Host: F

Epitope: Epitope of mAb 31H3 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: R32, R49, P56, F59
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive
Quantitative measurement: 1.39
Host: F

Epitope: Epitope of mAb 31H3 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: R32, R49, P56, F59
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive-Intermediate
Host: F

Epitope: Epitope of mAb 31G2 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: V342, S344, K347, K350
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive-Intermediate
Host: F

Epitope: Epitope of mAb 31G2 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: V342, S344, K347, K350
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive
Quantitative measurement: 3.34
Host: F

Epitope: Epitope of mAb 31E2 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: G238, L239, F296, K327, K347, K350
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive-Intermediate
Host: F

Epitope: Epitope of mAb 31E2 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: G238, L239, F296, K327, K347, K350
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive
Quantitative measurement: 17.0
Host: F

Epitope: Epitope of mAb 2B25.1 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: Y118, G120, E128, C309, I310
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.24

Epitope: Epitope of mAb 2B25.1 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: Y118, G120, E128, C309, I310
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb 1B22 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: E128, I310, P313, I315, N316
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive
Quantitative measurement: 1.05

Epitope: Epitope of mAb 1B22 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: E128, I310, P313, I315, N316
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of mAb 4B19 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: N7, N9, N11, D12, P13
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.54

Epitope: Epitope of mAb 4B19 on BoNT/B LC
Chemical type: Discontinuous protein residues
Discontinuous residues: N7, N9, N11, D12, P13
Source molecule (GenBank): P10844.3
Assay category: BCell
Result: Negative