Reference: Lori Blanchfield; Joseph J Sabatino; Laurel Lawrence; Brian D Evavold. "NFM Cross-Reactivity to MOG Does Not Expand a Critical Threshold Level of High-Affinity T Cells Necessary for Onset of Demyelinating Disease." Journal of immunology (Baltimore, Md. : 1950) (2017).

Epitope: MOG 35–55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 35-55
Source molecule (GenBank): AAA03180.1
Assay category: TCell
Result: Negative
Host: F 6-11 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 35–55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 35-55
Source molecule (GenBank): AAA03180.1
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 35–55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 35-55
Source molecule (GenBank): AAA03180.1
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 35–55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 35-55
Source molecule (GenBank): AAA03180.1
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 35–55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 35-55
Source molecule (GenBank): AAA03180.1
Assay category: TCell
Result: Positive
Host: F 6-11 weeks

Epitope: MOG 35–55
Chemical type: Peptide from protein
Sequence: MEVGWYRSPFSRVVHLYRNGK
Position: 35-55
Source molecule (GenBank): AAA03180.1
Assay category: TCell
Result: Negative
Host: F 6-11 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NFM 15-35
Chemical type: Peptide from protein
Sequence: RRVTETRSSFSRVSGSPSSGF
Position: 15-35
Source molecule (GenBank): P08553.4
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NFM 15-35
Chemical type: Peptide from protein
Sequence: RRVTETRSSFSRVSGSPSSGF
Position: 15-35
Source molecule (GenBank): P08553.4
Assay category: TCell
Result: Negative
Host: F 6-11 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NFM 15-35
Chemical type: Peptide from protein
Sequence: RRVTETRSSFSRVSGSPSSGF
Position: 15-35
Source molecule (GenBank): P08553.4
Assay category: TCell
Result: Positive
Host: F 6-11 weeks

Epitope: NFM 15-35
Chemical type: Peptide from protein
Sequence: RRVTETRSSFSRVSGSPSSGF
Position: 15-35
Source molecule (GenBank): P08553.4
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NFM 15-35
Chemical type: Peptide from protein
Sequence: RRVTETRSSFSRVSGSPSSGF
Position: 15-35
Source molecule (GenBank): P08553.4
Assay category: TCell
Result: Negative
Host: F 6-11 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NFM 15-35
Chemical type: Peptide from protein
Sequence: RRVTETRSSFSRVSGSPSSGF
Position: 15-35
Source molecule (GenBank): P08553.4
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NFM 15-35
Chemical type: Peptide from protein
Sequence: RRVTETRSSFSRVSGSPSSGF
Position: 15-35
Source molecule (GenBank): P08553.4
Assay category: TCell
Result: Negative
Host: F 6-11 weeks

Epitope: MOG 38-49
Chemical type: Peptide from protein
Sequence: GWYRSPFSRVVH
Position: 38-49
Source molecule (GenBank): AAA03180.1
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 38-49
Chemical type: Peptide from protein
Sequence: GWYRSPFSRVVH
Position: 38-49
Source molecule (GenBank): AAA03180.1
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: MOG 38-49
Chemical type: Peptide from protein
Sequence: GWYRSPFSRVVH
Position: 38-49
Source molecule (GenBank): AAA03180.1
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: T cell CD4+
Tissue: central nervous system (CNS)
Culture conditions: Short Term Restimulated

Epitope: NFM 18-30
Chemical type: Peptide from protein
Sequence: TETRSSFSRVSGS
Position: 18-30
Source molecule (GenBank): P08553.4
Assay category: TCell
Result: Negative
Host: F 6-11 weeks
Cell type: T cell CD4+
Tissue: central nervous system (CNS)
Culture conditions: Short Term Restimulated

Epitope: NFM 18-30
Chemical type: Peptide from protein
Sequence: TETRSSFSRVSGS
Position: 18-30
Source molecule (GenBank): P08553.4
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NFM 18-30
Chemical type: Peptide from protein
Sequence: TETRSSFSRVSGS
Position: 18-30
Source molecule (GenBank): P08553.4
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NFM 18-30 E19W, T20Y
Chemical type: Peptide, no natural source
Sequence: RRVTWYRSSFSRVSGSPSSGF
Assay category: TCell
Result: Positive
Host: F 6-11 weeks

Epitope: NFM 18-30 E19W, T20Y
Chemical type: Peptide, no natural source
Sequence: RRVTWYRSSFSRVSGSPSSGF
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NFM 18-30 E19W, T20Y
Chemical type: Peptide, no natural source
Sequence: RRVTWYRSSFSRVSGSPSSGF
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NFM 18-30 E19W, T20Y
Chemical type: Peptide, no natural source
Sequence: RRVTWYRSSFSRVSGSPSSGF
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NFM 18-30 T20Y
Chemical type: Peptide, no natural source
Sequence: RRVTEYRSSFSRVSGSPSSGF
Assay category: TCell
Result: Positive
Host: F 6-11 weeks

Epitope: NFM 18-30 T20Y
Chemical type: Peptide, no natural source
Sequence: RRVTEYRSSFSRVSGSPSSGF
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NFM 18-30 T20Y
Chemical type: Peptide, no natural source
Sequence: RRVTEYRSSFSRVSGSPSSGF
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NFM 18-30 T20Y
Chemical type: Peptide, no natural source
Sequence: RRVTEYRSSFSRVSGSPSSGF
Assay category: TCell
Result: Positive
Host: F 6-11 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NFM 18-30 S28V
Chemical type: Peptide, no natural source
Sequence: RRVTEYRSPFSRVVGSPSSGF
Assay category: TCell
Result: Negative
Host: F 6-11 weeks