Reference: Philip R Deitiker; Minako Oshima; R Glenn Smith; Dennis R Mosier; M Zouhair Atassi. "Subtle differences in HLA DQ haplotype-associated presentation of AChR alpha-chain peptides may suffice to mediate myasthenia gravis." Autoimmunity (2006).

Epitope: Peptide 1
Chemical type: Peptide from protein
Sequence: SEHETRLVAKLFKDYS
Position: 21-36
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-Intermediate
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 1
Chemical type: Peptide from protein
Sequence: SEHETRLVAKLFKDYS
Position: 21-36
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
MHC allele types: 314 96 103
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 1
Chemical type: Peptide from protein
Sequence: SEHETRLVAKLFKDYS
Position: 21-36
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-Intermediate
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 2
Chemical type: Peptide from protein
Sequence: FKDYSSVVRPVEDHRQ
Position: 32-47
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
MHC allele types: 314 103 315 524 96 97 93 105 658 659
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 3
Chemical type: Peptide from protein
Sequence: EDHRQVVEVTVGLQLI
Position: 43-58
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
MHC allele types: 105 93 97 96 315 659 658
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 3
Chemical type: Peptide from protein
Sequence: EDHRQVVEVTVGLQLI
Position: 43-58
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 4
Chemical type: Peptide from protein
Sequence: GLQLIQLINVDEVNQI
Position: 54-69
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 4
Chemical type: Peptide from protein
Sequence: GLQLIQLINVDEVNQI
Position: 54-69
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 4
Chemical type: Peptide from protein
Sequence: GLQLIQLINVDEVNQI
Position: 54-69
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 4
Chemical type: Peptide from protein
Sequence: GLQLIQLINVDEVNQI
Position: 54-69
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
MHC allele types: 314 93 524 103 658
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 5
Chemical type: Peptide from protein
Sequence: EVNQIVTTNVRLKQQW
Position: 65-80
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 5
Chemical type: Peptide from protein
Sequence: EVNQIVTTNVRLKQQW
Position: 65-80
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
MHC allele types: 105 93 524 103 658
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 7
Chemical type: Peptide from protein
Sequence: WNPDDYGGVKKIHIPS
Position: 87-102
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 7
Chemical type: Peptide from protein
Sequence: WNPDDYGGVKKIHIPS
Position: 87-102
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 7
Chemical type: Peptide from protein
Sequence: WNPDDYGGVKKIHIPS
Position: 87-102
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
MHC allele types: 105 96 524 315 659 658
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 7
Chemical type: Peptide from protein
Sequence: WNPDDYGGVKKIHIPS
Position: 87-102
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-Intermediate
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 9
Chemical type: Peptide from protein
Sequence: DLVLYNNADGDFAIVK
Position: 109-124
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
MHC allele types: 97 96 524 103 314 105
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 9
Chemical type: Peptide from protein
Sequence: DLVLYNNADGDFAIVK
Position: 109-124
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 9
Chemical type: Peptide from protein
Sequence: DLVLYNNADGDFAIVK
Position: 109-124
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 10
Chemical type: Peptide from protein
Sequence: FAIVKFTKVLLQYTGH
Position: 120-135
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-Intermediate
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 11
Chemical type: Peptide from protein
Sequence: QYTGHITWTPPAIFKS
Position: 131-146
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-Intermediate
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 11
Chemical type: Peptide from protein
Sequence: QYTGHITWTPPAIFKS
Position: 131-146
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-Intermediate
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 11
Chemical type: Peptide from protein
Sequence: QYTGHITWTPPAIFKS
Position: 131-146
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
MHC allele types: 314 97 524 315 659
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 12
Chemical type: Peptide from protein
Sequence: AIFKSYCEIIVTHFPFD
Position: 142-158
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-Intermediate
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 12
Chemical type: Peptide from protein
Sequence: AIFKSYCEIIVTHFPFD
Position: 142-158
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
MHC allele types: 105
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 12
Chemical type: Peptide from protein
Sequence: AIFKSYCEIIVTHFPFD
Position: 142-158
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 13
Chemical type: Peptide from protein
Sequence: HFPFDEQNCSMKLGTWT
Position: 154-170
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
MHC allele types: 105 524 658
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 14
Chemical type: Peptide from protein
Sequence: LGTWTYDGSVVAINPES
Position: 166-182
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 14
Chemical type: Peptide from protein
Sequence: LGTWTYDGSVVAINPES
Position: 166-182
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
MHC allele types: 314 97 93 315 103 659
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 15
Chemical type: Peptide from protein
Sequence: INPESDQPDLSNFMESG
Position: 178-194
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 15
Chemical type: Peptide from protein
Sequence: INPESDQPDLSNFMESG
Position: 178-194
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
MHC allele types: 314 105 93
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 17
Chemical type: Peptide from protein
Sequence: RGWKHSVTYSCCPDTPY
Position: 202-218
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive-High
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 17
Chemical type: Peptide from protein
Sequence: RGWKHSVTYSCCPDTPY
Position: 202-218
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
MHC allele types: 105 97 524 103 658
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 18
Chemical type: Peptide from protein
Sequence: PDTPYLDITYHFVMQRL
Position: 214-230
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Positive
MHC allele types: 105 103 97 96 524 658 659
Host:  11-79 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo