Reference: Ida Paciello; Emily J Rundlet; Ling Zhou; Giulia Realini; Federica Perrone; Giulio Pierleoni; Marco Troisi; Jeanne Postal; Florence Guivel-Benhassine; Françoise Porrot; Connor M Mullins; Davide Moschese; Maria Vittoria Cossu; Federico Sabaini; Silvia Accordini; Natasha Gianesini; Rebeca Passarelli Mantovani; Francesca Panza; Massimiliano Fabbiani; Mario Tumbarello; Spinello Antinori; Concetta Castilletti; Francesca Montagnani; Olivier Schwartz; Rino Rappuoli; Jason S McLellan; Emanuele Andreano. "Antigen-agnostic identification of poxvirus broadly neutralizing antibodies targeting OPG153." Science translational medicine (2025).

Epitope: Epitope of Fab 08E11 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: Q83, L87, N104, F107, K108, L110, N111, Y113, Y124, K133, H135, D136, G137, Y142, R157, Y160, K163, Q164, H167
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive
Quantitative measurement: 18.1

Epitope: Epitope of Fab 08E11 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: Q83, L87, N104, F107, K108, L110, N111, Y113, Y124, K133, H135, D136, G137, Y142, R157, Y160, K163, Q164, H167
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive
Quantitative measurement: 17.3

Epitope: Epitope of Fab 08E11 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: Q83, L87, N104, F107, K108, L110, N111, Y113, Y124, K133, H135, D136, G137, Y142, R157, Y160, K163, Q164, H167
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 08E11 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: Q83, L87, N104, F107, K108, L110, N111, Y113, Y124, K133, H135, D136, G137, Y142, R157, Y160, K163, Q164, H167
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 08E11 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: Q83, L87, N104, F107, K108, L110, N111, Y113, Y124, K133, H135, D136, G137, Y142, R157, Y160, K163, Q164, H167
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 08E11 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: Q83, L87, N104, F107, K108, L110, N111, Y113, Y124, K133, H135, D136, G137, Y142, R157, Y160, K163, Q164, H167
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 08E11 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: Q83, L87, N104, F107, K108, L110, N111, Y113, Y124, K133, H135, D136, G137, Y142, R157, Y160, K163, Q164, H167
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 08E11 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: Q83, L87, N104, F107, K108, L110, N111, Y113, Y124, K133, H135, D136, G137, Y142, R157, Y160, K163, Q164, H167
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 08E11 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: Q83, L87, N104, F107, K108, L110, N111, Y113, Y124, K133, H135, D136, G137, Y142, R157, Y160, K163, Q164, H167
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 08E11 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: Q83, L87, N104, F107, K108, L110, N111, Y113, Y124, K133, H135, D136, G137, Y142, R157, Y160, K163, Q164, H167
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive
Quantitative measurement: 18.5

Epitope: Epitope of Fab 08E11 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: Q83, L87, N104, F107, K108, L110, N111, Y113, Y124, K133, H135, D136, G137, Y142, R157, Y160, K163, Q164, H167
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 12I12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: D156, N194, S196, H197, H200, E201, Y203, D204, R205, V207, H210
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 12I12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: D156, N194, S196, H197, H200, E201, Y203, D204, R205, V207, H210
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 12I12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: D156, N194, S196, H197, H200, E201, Y203, D204, R205, V207, H210
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 12I12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: D156, N194, S196, H197, H200, E201, Y203, D204, R205, V207, H210
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of Fab 12I12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: D156, N194, S196, H197, H200, E201, Y203, D204, R205, V207, H210
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.2

Epitope: Epitope of Fab 12I12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: D156, N194, S196, H197, H200, E201, Y203, D204, R205, V207, H210
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 12I12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: D156, N194, S196, H197, H200, E201, Y203, D204, R205, V207, H210
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 12I12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: D156, N194, S196, H197, H200, E201, Y203, D204, R205, V207, H210
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 12I12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: D156, N194, S196, H197, H200, E201, Y203, D204, R205, V207, H210
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.2

Epitope: Epitope of Fab 02M12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: E270, K271, F272, F294, N295, K296, K297, G298, I299, V300, K301, T303, E304, D305, N364
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 02M12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: E270, K271, F272, F294, N295, K296, K297, G298, I299, V300, K301, T303, E304, D305, N364
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive
Quantitative measurement: 37.7

Epitope: Epitope of Fab 02M12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: E270, K271, F272, F294, N295, K296, K297, G298, I299, V300, K301, T303, E304, D305, N364
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive
Quantitative measurement: 30.7

Epitope: Epitope of Fab 02M12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: E270, K271, F272, F294, N295, K296, K297, G298, I299, V300, K301, T303, E304, D305, N364
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive
Quantitative measurement: 16.6

Epitope: Epitope of Fab 02M12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: E270, K271, F272, F294, N295, K296, K297, G298, I299, V300, K301, T303, E304, D305, N364
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of Fab 02M12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: E270, K271, F272, F294, N295, K296, K297, G298, I299, V300, K301, T303, E304, D305, N364
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of Fab 02M12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: E270, K271, F272, F294, N295, K296, K297, G298, I299, V300, K301, T303, E304, D305, N364
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 02M12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: E270, K271, F272, F294, N295, K296, K297, G298, I299, V300, K301, T303, E304, D305, N364
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab 02M12 on MPXV OPG153
Chemical type: Discontinuous protein residues
Discontinuous residues: E270, K271, F272, F294, N295, K296, K297, G298, I299, V300, K301, T303, E304, D305, N364
Source molecule (GenBank): NP_536565.1
Assay category: BCell
Result: Positive