Reference: Alessandro Angelini; Yoshishige Miyabe; Daniel Newsted; Byron H Kwan; Chie Miyabe; Ryan L Kelly; Misha N Jamy; Andrew D Luster; K Dane Wittrup. "Directed evolution of broadly crossreactive chemokine-blocking antibodies efficacious in arthritis." Nature communications (2018).

Epitope: SA129
Chemical type: Discontinuous protein residues
Discontinuous residues: Q47, T48, L49, G51, I52, N56, K79, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: SA129
Chemical type: Discontinuous protein residues
Discontinuous residues: Q47, T48, L49, G51, I52, N56, K79, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA129
Chemical type: Discontinuous protein residues
Discontinuous residues: Q47, T48, L49, G51, I52, N56, K79, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA129
Chemical type: Discontinuous protein residues
Discontinuous residues: Q47, T48, L49, G51, I52, N56, K79, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-High
Quantitative measurement: 9.2

Epitope: SA129
Chemical type: Discontinuous protein residues
Discontinuous residues: Q47, T48, L49, G51, I52, N56, K79, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive
Quantitative measurement: 43.6

Epitope: SA129
Chemical type: Discontinuous protein residues
Discontinuous residues: Q47, T48, L49, G51, I52, N56, K79, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-High
Quantitative measurement: 2.9

Epitope: SA129
Chemical type: Discontinuous protein residues
Discontinuous residues: Q47, T48, L49, G51, I52, N56, K79, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA129
Chemical type: Discontinuous protein residues
Discontinuous residues: Q47, T48, L49, G51, I52, N56, K79, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-High
Quantitative measurement: 2.7

Epitope: SA129
Chemical type: Discontinuous protein residues
Discontinuous residues: Q47, T48, L49, G51, I52, N56, K79, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA129
Chemical type: Discontinuous protein residues
Discontinuous residues: Q47, T48, L49, G51, I52, N56, K79, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA129
Chemical type: Discontinuous protein residues
Discontinuous residues: Q47, T48, L49, G51, I52, N56, K79, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-High

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 1590.0

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive
Quantitative measurement: 33.7

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 356.0

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 836.0

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 5000.0

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive
Quantitative measurement: 14.7

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive
Quantitative measurement: 16.7

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive
Quantitative measurement: 29.4

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive
Quantitative measurement: 31.1

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-High

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-High

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-High

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive
Quantitative measurement: 96.7

Epitope: SA138
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, L46, Q47, T48, L49, I52, N80, G81, R82, A84
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Negative
Quantitative measurement: 32135.0

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Negative
Quantitative measurement: 43890.0

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 1034.0

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 1770.0

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 2018.0

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 2125.0

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 2647.0

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Negative
Quantitative measurement: 16033.0

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 751.0

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 528.0

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 591.0

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 666.0

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 853.0

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-High

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-High

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-High

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 1433.0

Epitope: SA157
Chemical type: Discontinuous protein residues
Discontinuous residues: I52, H53, K55, N56, K79, N80, G81, I92, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: Ab276
Chemical type: Discontinuous protein residues
Discontinuous residues: T48, L49, Q50, G51, I52, H53, K55, N56, K79, N80, G81, R82, A84, I92, K95, K99, K105
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive

Epitope: Ab275
Chemical type: Discontinuous protein residues
Discontinuous residues: R42, Q44, L46, Q47, T48, L49, Q50, G51, I52, N56, K79, N80, G81, R82, K83, A84, N87
Source molecule (GenBank): P09341.1
Assay category: BCell
Result: Positive