Reference: Sophie A Valkenburg; Tracy M Josephs; E Bridie Clemens; Emma J Grant; Thi H O Nguyen; George C Wang; David A Price; Adrian Miller; Steven Y C Tong; Paul G Thomas; Peter C Doherty; Jamie Rossjohn; Stephanie Gras; Katherine Kedzierska. "Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses." Proceedings of the National Academy of Sciences of the United States of America (2016).

Epitope: M1-L3W
Chemical type: Peptide from protein
Sequence: GIWGFVFTL
Position: 58-66
Source molecule (GenBank): ADG59529.1
Assay category: TCell
Result: Positive-High
Host:  22-25 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1-L3W
Chemical type: Peptide from protein
Sequence: GIWGFVFTL
Position: 58-66
Source molecule (GenBank): ADG59529.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1-L3W
Chemical type: Peptide from protein
Sequence: GIWGFVFTL
Position: 58-66
Source molecule (GenBank): ADG59529.1
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 600000.0

Epitope: M1-L3W
Chemical type: Peptide from protein
Sequence: GIWGFVFTL
Position: 58-66
Source molecule (GenBank): ADG59529.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.1

Epitope: M1-L3W
Chemical type: Peptide from protein
Sequence: GIWGFVFTL
Position: 58-66
Source molecule (GenBank): ADG59529.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 65.9

Epitope: M1-F5L
Chemical type: Peptide from protein
Sequence: GILGLVFTL
Position: 58-66
Source molecule (GenBank): ABC84521.1
Assay category: TCell
Result: Positive
Host:  22-25 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1-F5L
Chemical type: Peptide from protein
Sequence: GILGLVFTL
Position: 58-66
Source molecule (GenBank): ABC84521.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1-F5L
Chemical type: Peptide from protein
Sequence: GILGLVFTL
Position: 58-66
Source molecule (GenBank): ABC84521.1
Assay category: TCell
Result: Positive
Quantitative measurement: 2.5

Epitope: M1-F5L
Chemical type: Peptide from protein
Sequence: GILGLVFTL
Position: 58-66
Source molecule (GenBank): ABC84521.1
Assay category: TCell
Result: Positive-Low
Quantitative measurement: 200000.0

Epitope: M1-F5L
Chemical type: Peptide from protein
Sequence: GILGLVFTL
Position: 58-66
Source molecule (GenBank): ABC84521.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.03

Epitope: M1-F5L
Chemical type: Peptide from protein
Sequence: GILGLVFTL
Position: 58-66
Source molecule (GenBank): ABC84521.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.5

Epitope: M1-F5L
Chemical type: Peptide from protein
Sequence: GILGLVFTL
Position: 58-66
Source molecule (GenBank): ABC84521.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 65.6

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: bronchial aveolar lavage (BAL)
Culture conditions: Direct Ex Vivo

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: bronchial aveolar lavage (BAL)
Culture conditions: Direct Ex Vivo

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Quantitative measurement: 1790.0

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Host:  22-25 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive-High
Host:  22-25 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Host:  22-25 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 (58)
Chemical type: Peptide from protein
Sequence: GILGFVFTL
Position: 58-66
Source molecule (GenBank): P03485.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 65.8

Epitope: M1-G1W
Chemical type: Peptide from protein
Sequence: WILGFVFTL
Position: 58-66
Source molecule (GenBank): ABR22242.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1-I2T
Chemical type: Peptide from protein
Sequence: GTLGFVFTL
Position: 58-66
Source molecule (GenBank): AAT12044.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1-I2M
Chemical type: Peptide from protein
Sequence: GMLGFVFTL
Position: 58-66
Source molecule (GenBank): ACZ48143.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1-I2V
Chemical type: Peptide from protein
Sequence: GVLGFVFTL
Position: 58-66
Source molecule (GenBank): BAF57597.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1-F5V
Chemical type: Peptide from protein
Sequence: GILGVVFTL
Position: 58-66
Source molecule (GenBank): ABD79113.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1-V6I
Chemical type: Peptide from protein
Sequence: GILGFIFTL
Position: 58-66
Source molecule (GenBank): AAO46406.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1-F7Y
Chemical type: Peptide from protein
Sequence: GILGFVYTL
Position: 58-66
Source molecule (GenBank): ABJ09295.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PA (46)
Chemical type: Peptide from protein
Sequence: FMYSDFHFI
Position: 46-54
Source molecule (GenBank): NP_040986.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: bronchial aveolar lavage (BAL)
Culture conditions: Direct Ex Vivo

Epitope: PA (46)
Chemical type: Peptide from protein
Sequence: FMYSDFHFI
Position: 46-54
Source molecule (GenBank): NP_040986.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: bronchial aveolar lavage (BAL)
Culture conditions: Direct Ex Vivo

Epitope: NP (122)
Chemical type: Peptide from protein
Sequence: AIMDKKIIL
Position: 28-36
Source molecule (GenBank): AAD39466.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: bronchial aveolar lavage (BAL)
Culture conditions: Direct Ex Vivo

Epitope: NP (122)
Chemical type: Peptide from protein
Sequence: AIMDKKIIL
Position: 28-36
Source molecule (GenBank): AAD39466.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: bronchial aveolar lavage (BAL)
Culture conditions: Direct Ex Vivo

Epitope: NP (265)
Chemical type: Peptide from protein
Sequence: ILRGSVAHK
Position: 265-273
Source molecule (GenBank): CAA24268.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NP (418) variant
Chemical type: Peptide from protein
Sequence: LPFDRPTIM
Position: 418-426
Source molecule (GenBank): P15682.1
Assay category: TCell
Result: Positive-Low
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NP (418) variant
Chemical type: Peptide from protein
Sequence: LPFDKPTIM
Position: 418-426
Source molecule (GenBank): P03467.1
Assay category: TCell
Result: Positive-Low
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NP (418) variant
Chemical type: Peptide from protein
Sequence: LPFDKSTIM
Position: 418-426
Source molecule (GenBank): Q07531.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NP (418) variant
Chemical type: Peptide from protein
Sequence: LPFDKTTIM
Position: 418-426
Source molecule (GenBank): AGQ47768.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NP (418) variant
Chemical type: Peptide from protein
Sequence: LPFEKSTIM
Position: 418-426
Source molecule (GenBank): AAR12356.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NP (418) variant
Chemical type: Peptide from protein
Sequence: LPFDKATIM
Position: 418-426
Source molecule (GenBank): ADE28751.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NP (418) variant
Chemical type: Peptide from protein
Sequence: LPFDIATIM
Position: 418-426
Source molecule (GenBank): ACX46218.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NP (418) variant
Chemical type: Peptide from protein
Sequence: LPFEKSTVM
Position: 418-426
Source molecule (GenBank): ABC46569.1
Assay category: TCell
Result: Positive-Low
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NP (418) variant
Chemical type: Peptide from protein
Sequence: LPFERATVM
Position: 418-426
Source molecule (GenBank): ACP41106.1
Assay category: TCell
Result: Positive-Low
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NP (418) variant
Chemical type: Peptide from protein
Sequence: LPFERATIM
Position: 418-426
Source molecule (GenBank): AAV48837.1
Assay category: TCell
Result: Positive-Low
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated