Reference: Laura A VanBlargan; Lucas J Adams; Zhuoming Liu; Rita E Chen; Pavlo Gilchuk; Saravanan Raju; Brittany K Smith; Haiyan Zhao; James Brett Case; Emma S Winkler; Bradley M Whitener; Lindsay Droit; Ishmael D Aziati; Traci L Bricker; Astha Joshi; Pei-Yong Shi; Adrian Creanga; Amarendra Pegu; Scott A Handley; David Wang; Adrianus C M Boon; James E Crowe; Sean P J Whelan; Daved H Fremont; Michael S Diamond. "A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope." Immunity (2021).

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 6.5

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-38 Fab on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, N439, N440, L441, D442, S443, K444, V445, G446, N448, Y449, N450, Y451,P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-01 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, A352, G446, N450, L452, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-01 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, A352, G446, N450, L452, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-01 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, A352, G446, N450, L452, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-01 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, A352, G446, N450, L452, S494
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-02 and SARS2-55 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, L452, E484
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-02 and SARS2-55 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, L452, E484
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-02 and SARS2-55 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, L452, E484
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-02 and SARS2-55 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, L452, E484
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-02 and SARS2-55 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, L452, E484
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-02 and SARS2-55 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, L452, E484
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-02 and SARS2-55 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, L452, E484
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-02 and SARS2-55 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, L452, E484
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-34 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q474, G476, S477, T478, P479, F486, P499
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-34 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q474, G476, S477, T478, P479, F486, P499
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-34 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q474, G476, S477, T478, P479, F486, P499
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative

Epitope: Epitope of SARS2-34 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Q474, G476, S477, T478, P479, F486, P499
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-71 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G476, S477, T478, P479, F486, P499
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative

Epitope: Epitope of SARS2-71 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G476, S477, T478, P479, F486, P499
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-71 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G476, S477, T478, P479, F486, P499
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-71 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G476, S477, T478, P479, F486, P499
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-31 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: K378, R408, G504
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-31 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: K378, R408, G504
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-31 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: K378, R408, G504
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-31 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: K378, R408, G504
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-31 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: K378, R408, G504
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of SARS2-31 on SARS-CoV-2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: K378, R408, G504
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Negative