Reference: Walter G Ferlin; Evelyne Mougneau; Stéphanie Hugues; Heiner Appel; Mei-Huei Jang; Julie Cazareth; Lucie Beaudoin; Corinne Schricke; Agnès Lehuen; Kai W Wucherpfennig; Nicolas Glaichenhaus. "Self-peptides that bind with low affinity to the diabetes-associated I-A(g7) molecule readily induce T cell tolerance in non-obese diabetic mice." European journal of immunology (2004).

Epitope: LACK 54
Chemical type: Peptide from protein
Sequence: LRDGHEDWVSSICFSP
Position: 145-160
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 58
Chemical type: Peptide from protein
Sequence: HEDWVSSICFSPSLEH
Position: 149-164
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 62
Chemical type: Peptide from protein
Sequence: VSSICFSPSLEHPIVV
Position: 153-168
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 66
Chemical type: Peptide from protein
Sequence: CFSPSLEHPIVVSGSW
Position: 157-172
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 70
Chemical type: Peptide from protein
Sequence: SLEHPIVVSGSWDNTI
Position: 161-176
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 74
Chemical type: Peptide from protein
Sequence: PIVVSGSWDNTIKVWN
Position: 165-180
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 82
Chemical type: Peptide from protein
Sequence: DNTIKVWNVNGGKCER
Position: 173-188
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 86
Chemical type: Peptide from protein
Sequence: KVWNVNGGKCERTLKG
Position: 177-192
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 94
Chemical type: Peptide from protein
Sequence: KCERTLKGHSNYVSTV
Position: 185-200
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 98
Chemical type: Peptide from protein
Sequence: TLKGHSNYVSTVTVSP
Position: 189-204
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Positive
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 98
Chemical type: Peptide from protein
Sequence: TLKGHSNYVSTVTVSP
Position: 189-204
Source molecule (GenBank): Q25306.1
Assay category: MhcBinding
Result: Negative

Epitope: LACK 102
Chemical type: Peptide from protein
Sequence: HSNYVSTVTVSPDGSL
Position: 193-208
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Positive
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 102
Chemical type: Peptide from protein
Sequence: HSNYVSTVTVSPDGSL
Position: 193-208
Source molecule (GenBank): Q25306.1
Assay category: MhcBinding
Result: Positive

Epitope: LACK 106
Chemical type: Peptide from protein
Sequence: VSTVTVSPDGSLCASG
Position: 197-212
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 110
Chemical type: Peptide from protein
Sequence: TVSPDGSLCASGGKDG
Position: 201-216
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 114
Chemical type: Peptide from protein
Sequence: DGSLCASGGKDGAALL
Position: 205-220
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 122
Chemical type: Peptide from protein
Sequence: GKDGAALLWDLSTGEQ
Position: 213-228
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 126
Chemical type: Peptide from protein
Sequence: AALLWDLSTGEQLFKI
Position: 217-232
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 130
Chemical type: Peptide from protein
Sequence: WDLSTGEQLFKINVES
Position: 221-236
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 134
Chemical type: Peptide from protein
Sequence: TGEQLFKINVESPINQ
Position: 225-240
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 138
Chemical type: Peptide from protein
Sequence: LFKINVESPINQIGFS
Position: 229-244
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 142
Chemical type: Peptide from protein
Sequence: NVESPINQIGFSPNRF
Position: 233-248
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 146
Chemical type: Peptide from protein
Sequence: PINQIGFSPNRFWMCV
Position: 237-252
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 150
Chemical type: Peptide from protein
Sequence: IGFSPNRFWMCVATER
Position: 241-256
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 154
Chemical type: Peptide from protein
Sequence: PNRFWMCVATERSLSV
Position: 245-260
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 158
Chemical type: Peptide from protein
Sequence: WMCVATERSLSVYDLE
Position: 249-264
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 162
Chemical type: Peptide from protein
Sequence: ATERSLSVYDLESKAV
Position: 253-268
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 166
Chemical type: Peptide from protein
Sequence: SLSVYDLESKAVIAEL
Position: 257-272
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Positive
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 166
Chemical type: Peptide from protein
Sequence: SLSVYDLESKAVIAEL
Position: 257-272
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Positive
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 166
Chemical type: Peptide from protein
Sequence: SLSVYDLESKAVIAEL
Position: 257-272
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Positive
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 166
Chemical type: Peptide from protein
Sequence: SLSVYDLESKAVIAEL
Position: 257-272
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Positive
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 166
Chemical type: Peptide from protein
Sequence: SLSVYDLESKAVIAEL
Position: 257-272
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Positive
Host:  8-10 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: LACK 166
Chemical type: Peptide from protein
Sequence: SLSVYDLESKAVIAEL
Position: 257-272
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Positive
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 166
Chemical type: Peptide from protein
Sequence: SLSVYDLESKAVIAEL
Position: 257-272
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Positive
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 166
Chemical type: Peptide from protein
Sequence: SLSVYDLESKAVIAEL
Position: 257-272
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Positive
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 166
Chemical type: Peptide from protein
Sequence: SLSVYDLESKAVIAEL
Position: 257-272
Source molecule (GenBank): Q25306.1
Assay category: MhcBinding
Result: Positive

Epitope: LACK 170
Chemical type: Peptide from protein
Sequence: YDLESKAVIAELTPDG
Position: 261-276
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Positive
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 170
Chemical type: Peptide from protein
Sequence: YDLESKAVIAELTPDG
Position: 261-276
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Positive
Host:  8-10 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: LACK 170
Chemical type: Peptide from protein
Sequence: YDLESKAVIAELTPDG
Position: 261-276
Source molecule (GenBank): Q25306.1
Assay category: MhcBinding
Result: Positive

Epitope: LACK 174
Chemical type: Peptide from protein
Sequence: SKAVIAELTPDGAKPS
Position: 265-280
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 178
Chemical type: Peptide from protein
Sequence: IAELTPDGAKPSECIS
Position: 269-284
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 182
Chemical type: Peptide from protein
Sequence: TPDGAKPSECISIAWS
Position: 273-288
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 186
Chemical type: Peptide from protein
Sequence: AKPSECISIAWSADGN
Position: 277-292
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 190
Chemical type: Peptide from protein
Sequence: ECISIAWSADGNTLYS
Position: 281-296
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 198
Chemical type: Peptide from protein
Sequence: ADGNTLYSGHKDNLIR
Position: 289-304
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: LACK 202
Chemical type: Peptide from protein
Sequence: TLYSGHKDNLIRVWSI
Position: 293-308
Source molecule (GenBank): Q25306.1
Assay category: TCell
Result: Negative
Host:  8-10 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: transferrin 55-68
Chemical type: Peptide from protein
Sequence: GHNYVTAIRNQQEG
Position: 335-348
Source molecule (GenBank): Q921I1.1
Assay category: MhcBinding
Result: Positive

Epitope: GAD 206-220
Chemical type: Peptide from protein
Sequence: TYEIAPVFVLLEYVT
Position: 206-220
Source molecule (GenBank): P48320.1
Assay category: MhcBinding
Result: Positive

Epitope: MAS 560-574
Chemical type: Peptide from protein
Sequence: KPKATAEQLKTVMDD
Position: 560-574
Source molecule (GenBank): P07724.3
Assay category: MhcBinding
Result: Positive

Epitope: INS 9-23
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Positive