Reference: Laurie G Landry; Amanda M Anderson; Holger A Russ; Liping Yu; Sally C Kent; Mark A Atkinson; Clayton E Mathews; Aaron W Michels; Maki Nakayama. "Proinsulin-Reactive CD4 T Cells in the Islets of Type 1 Diabetes Organ Donors." Frontiers in endocrinology (2021).

Epitope: PPI:24-38
Chemical type: Peptide from protein
Sequence: AFVNQHLCGSHLVEA
Position: 24-38
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:24-38
Chemical type: Peptide from protein
Sequence: AFVNQHLCGSHLVEA
Position: 24-38
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:29-43
Chemical type: Peptide from protein
Sequence: HLCGSHLVEALYLVC
Position: 29-43
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:29-43
Chemical type: Peptide from protein
Sequence: HLCGSHLVEALYLVC
Position: 29-43
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:33-47
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:33-47
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:33-47
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:33-47
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERG
Position: 33-47
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:36-50
Chemical type: Peptide from protein
Sequence: VEALYLVCGERGFFY
Position: 36-50
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:37-51
Chemical type: Peptide from protein
Sequence: EALYLVCGERGFFYT
Position: 37-51
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:37-51
Chemical type: Peptide from protein
Sequence: EALYLVCGERGFFYT
Position: 37-51
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:37-51
Chemical type: Peptide from protein
Sequence: EALYLVCGERGFFYT
Position: 37-51
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:40-54
Chemical type: Peptide from protein
Sequence: YLVCGERGFFYTPKT
Position: 40-54
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:40-54
Chemical type: Peptide from protein
Sequence: YLVCGERGFFYTPKT
Position: 40-54
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:40-54
Chemical type: Peptide from protein
Sequence: YLVCGERGFFYTPKT
Position: 40-54
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:40-54
Chemical type: Peptide from protein
Sequence: YLVCGERGFFYTPKT
Position: 40-54
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:40-54
Chemical type: Peptide from protein
Sequence: YLVCGERGFFYTPKT
Position: 40-54
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:40-54
Chemical type: Peptide from protein
Sequence: YLVCGERGFFYTPKT
Position: 40-54
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:40-54
Chemical type: Peptide from protein
Sequence: YLVCGERGFFYTPKT
Position: 40-54
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:40-54
Chemical type: Peptide from protein
Sequence: YLVCGERGFFYTPKT
Position: 40-54
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:55-69
Chemical type: Peptide from protein
Sequence: RREAEDLQVGQVELG
Position: 55-69
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:55-69
Chemical type: Peptide from protein
Sequence: RREAEDLQVGQVELG
Position: 55-69
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:58-72
Chemical type: Peptide from protein
Sequence: AEDLQVGQVELGGGP
Position: 58-72
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:58-72
Chemical type: Peptide from protein
Sequence: AEDLQVGQVELGGGP
Position: 58-72
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:72-87
Chemical type: Peptide from protein
Sequence: PGAGSLQPLALEGSLQ
Position: 72-87
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:72-87
Chemical type: Peptide from protein
Sequence: PGAGSLQPLALEGSLQ
Position: 72-87
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:72-87
Chemical type: Peptide from protein
Sequence: PGAGSLQPLALEGSLQ
Position: 72-87
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:72-87
Chemical type: Peptide from protein
Sequence: PGAGSLQPLALEGSLQ
Position: 72-87
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:72-87
Chemical type: Peptide from protein
Sequence: PGAGSLQPLALEGSLQ
Position: 72-87
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:86-100
Chemical type: Peptide from protein
Sequence: LQKRGIVEQCCTSIC
Position: 86-100
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:86-100
Chemical type: Peptide from protein
Sequence: LQKRGIVEQCCTSIC
Position: 86-100
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:87-101
Chemical type: Peptide from protein
Sequence: QKRGIVEQCCTSICS
Position: 87-101
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:87-101
Chemical type: Peptide from protein
Sequence: QKRGIVEQCCTSICS
Position: 87-101
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:94-108
Chemical type: Peptide from protein
Sequence: QCCTSICSLYQLENY
Position: 94-108
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:94-108
Chemical type: Peptide from protein
Sequence: QCCTSICSLYQLENY
Position: 94-108
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:22-36
Chemical type: Peptide from protein
Sequence: AAAFVNQHLCGSHLV
Position: 22-36
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:23-37
Chemical type: Peptide from protein
Sequence: AAFVNQHLCGSHLVE
Position: 23-37
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:25-39
Chemical type: Peptide from protein
Sequence: FVNQHLCGSHLVEAL
Position: 25-39
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:28-42
Chemical type: Peptide from protein
Sequence: QHLCGSHLVEALYLV
Position: 28-42
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:30-44
Chemical type: Peptide from protein
Sequence: LCGSHLVEALYLVCG
Position: 30-44
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:31-45
Chemical type: Peptide from protein
Sequence: CGSHLVEALYLVCGE
Position: 31-45
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:32-46
Chemical type: Peptide from protein
Sequence: GSHLVEALYLVCGER
Position: 32-46
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:34-48
Chemical type: Peptide from protein
Sequence: HLVEALYLVCGERGF
Position: 34-48
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:35-49
Chemical type: Peptide from protein
Sequence: LVEALYLVCGERGFF
Position: 35-49
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:38-52
Chemical type: Peptide from protein
Sequence: ALYLVCGERGFFYTP
Position: 38-52
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:39-53
Chemical type: Peptide from protein
Sequence: LYLVCGERGFFYTPK
Position: 39-53
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:41-55
Chemical type: Peptide from protein
Sequence: LVCGERGFFYTPKTR
Position: 41-55
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:56-70
Chemical type: Peptide from protein
Sequence: REAEDLQVGQVELGG
Position: 56-70
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:57-71
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVELGGG
Position: 57-71
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:59-73
Chemical type: Peptide from protein
Sequence: EDLQVGQVELGGGPG
Position: 59-73
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:73-87
Chemical type: Peptide from protein
Sequence: GAGSLQPLALEGSLQ
Position: 73-87
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:74-88
Chemical type: Peptide from protein
Sequence: AGSLQPLALEGSLQK
Position: 74-88
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:75-89
Chemical type: Peptide from protein
Sequence: GSLQPLALEGSLQKR
Position: 75-89
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:77-91
Chemical type: Peptide from protein
Sequence: LQPLALEGSLQKRGI
Position: 77-91
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:81-95
Chemical type: Peptide from protein
Sequence: ALEGSLQKRGIVEQC
Position: 81-95
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:88-102
Chemical type: Peptide from protein
Sequence: KRGIVEQCCTSICSL
Position: 88-102
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:89-103
Chemical type: Peptide from protein
Sequence: RGIVEQCCTSICSLY
Position: 89-103
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:92-106
Chemical type: Peptide from protein
Sequence: VEQCCTSICSLYQLE
Position: 92-106
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:93-107
Chemical type: Peptide from protein
Sequence: EQCCTSICSLYQLEN
Position: 93-107
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI:95-109
Chemical type: Peptide from protein
Sequence: CCTSICSLYQLENYC
Position: 95-109
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI 33-53 cit
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERGFFYTPK
Position: 33-53
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI 33-53 cit
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERGFFYTPK
Position: 33-53
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI 33-53 cit
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERGFFYTPK
Position: 33-53
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI 33-53 cit
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERGFFYTPK
Position: 33-53
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI 33-53 cit
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERGFFYTPK
Position: 33-53
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI 33-53 cit
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERGFFYTPK
Position: 33-53
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI 33-53 cit
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERGFFYTPK
Position: 33-53
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI 33-53 cit
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERGFFYTPK
Position: 33-53
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered

Epitope: PPI 33-53 cit
Chemical type: Peptide from protein
Sequence: SHLVEALYLVCGERGFFYTPK
Position: 33-53
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymphoid
Culture conditions: Engineered