Reference: Luca Simonelli; Mattia Pedotti; Martina Beltramello; Elsa Livoti; Luigi Calzolai; Federica Sallusto; Antonio Lanzavecchia; Luca Varani. "Rational engineering of a human anti-dengue antibody through experimentally validated computational docking." PloS one (2013).

Epitope: mAb DV32.6 (DENV1 Env DIII)
Chemical type: Discontinuous protein residues
Discontinuous residues: F586, K587, L588, E589, K590, E591, V592, A593, E594, T595, G598, T599, V600, L601, V602, Q603, V604, K605, E642, I647, E648, S670, F672, K674, G675, S676, S677, I678, G679, K680
Source molecule (GenBank): BAU61357.1
Assay category: BCell
Result: Positive
Quantitative measurement: 145.0

Epitope: mAb DV32.6 (DENV1 Env DIII)
Chemical type: Discontinuous protein residues
Discontinuous residues: F586, K587, L588, E589, K590, E591, V592, A593, E594, T595, G598, T599, V600, L601, V602, Q603, V604, K605, E642, I647, E648, S670, F672, K674, G675, S676, S677, I678, G679, K680
Source molecule (GenBank): BAU61357.1
Assay category: BCell
Result: Positive

Epitope: mAb DV32.6 (DENV1 Env DIII)
Chemical type: Discontinuous protein residues
Discontinuous residues: F586, K587, L588, E589, K590, E591, V592, A593, E594, T595, G598, T599, V600, L601, V602, Q603, V604, K605, E642, I647, E648, S670, F672, K674, G675, S676, S677, I678, G679, K680
Source molecule (GenBank): BAU61357.1
Assay category: BCell
Result: Positive

Epitope: mAb DV32.6 (DENV1 Env DIII)
Chemical type: Discontinuous protein residues
Discontinuous residues: F586, K587, L588, E589, K590, E591, V592, A593, E594, T595, G598, T599, V600, L601, V602, Q603, V604, K605, E642, I647, E648, S670, F672, K674, G675, S676, S677, I678, G679, K680
Source molecule (GenBank): BAU61357.1
Assay category: BCell
Result: Positive

Epitope: mAb DV32.6 (DENV1 Env DIII)
Chemical type: Discontinuous protein residues
Discontinuous residues: F586, K587, L588, E589, K590, E591, V592, A593, E594, T595, G598, T599, V600, L601, V602, Q603, V604, K605, E642, I647, E648, S670, F672, K674, G675, S676, S677, I678, G679, K680
Source molecule (GenBank): BAU61357.1
Assay category: BCell
Result: Positive

Epitope: mAb DV32.6 (DENV2 Env DIII)
Chemical type: Discontinuous protein residues
Discontinuous residues: F586, K587, V588, V589, K590, E591, I592, A593, E594, T595, H597, T599, I600, V601, R603, Q605, V645, N646, I647, E648, S676, S677
Source molecule (GenBank): AIU39216.1
Assay category: BCell
Result: Positive
Quantitative measurement: 7.0

Epitope: mAb DV32.6 (DENV2 Env DIII)
Chemical type: Discontinuous protein residues
Discontinuous residues: F586, K587, V588, V589, K590, E591, I592, A593, E594, T595, H597, T599, I600, V601, R603, Q605, V645, N646, I647, E648, S676, S677
Source molecule (GenBank): AIU39216.1
Assay category: BCell
Result: Positive

Epitope: mAb DV32.6 (DENV2 Env DIII)
Chemical type: Discontinuous protein residues
Discontinuous residues: F586, K587, V588, V589, K590, E591, I592, A593, E594, T595, H597, T599, I600, V601, R603, Q605, V645, N646, I647, E648, S676, S677
Source molecule (GenBank): AIU39216.1
Assay category: BCell
Result: Positive

Epitope: mAb DV32.6 (DENV2 Env DIII)
Chemical type: Discontinuous protein residues
Discontinuous residues: F586, K587, V588, V589, K590, E591, I592, A593, E594, T595, H597, T599, I600, V601, R603, Q605, V645, N646, I647, E648, S676, S677
Source molecule (GenBank): AIU39216.1
Assay category: BCell
Result: Positive

Epitope: mAb DV32.6 (DENV2 Env DIII)
Chemical type: Discontinuous protein residues
Discontinuous residues: F586, K587, V588, V589, K590, E591, I592, A593, E594, T595, H597, T599, I600, V601, R603, Q605, V645, N646, I647, E648, S676, S677
Source molecule (GenBank): AIU39216.1
Assay category: BCell
Result: Positive

Epitope: mAb DV32.6 (DENV3 Env DIII)
Chemical type: Discontinuous protein residues
Discontinuous residues: V585, L586, K587, K588, E589, V590, S591, E592, G596, T597, I598, L599, I600, K601, V602, E603, V643, N644, I645, I667, W669, S674
Source molecule (GenBank): P27915.1
Assay category: BCell
Result: Positive

Epitope: mAb DV32.6 (DENV3 Env DIII)
Chemical type: Discontinuous protein residues
Discontinuous residues: V585, L586, K587, K588, E589, V590, S591, E592, G596, T597, I598, L599, I600, K601, V602, E603, V643, N644, I645, I667, W669, S674
Source molecule (GenBank): P27915.1
Assay category: BCell
Result: Positive
Quantitative measurement: 73.0

Epitope: mAb DV32.6 (DENV3 Env DIII)
Chemical type: Discontinuous protein residues
Discontinuous residues: V585, L586, K587, K588, E589, V590, S591, E592, G596, T597, I598, L599, I600, K601, V602, E603, V643, N644, I645, I667, W669, S674
Source molecule (GenBank): P27915.1
Assay category: BCell
Result: Positive

Epitope: mAb DV32.6 (DENV3 Env DIII)
Chemical type: Discontinuous protein residues
Discontinuous residues: V585, L586, K587, K588, E589, V590, S591, E592, G596, T597, I598, L599, I600, K601, V602, E603, V643, N644, I645, I667, W669, S674
Source molecule (GenBank): P27915.1
Assay category: BCell
Result: Positive

Epitope: mAb DV32.6 (DENV3 Env DIII)
Chemical type: Discontinuous protein residues
Discontinuous residues: V585, L586, K587, K588, E589, V590, S591, E592, G596, T597, I598, L599, I600, K601, V602, E603, V643, N644, I645, I667, W669, S674
Source molecule (GenBank): P27915.1
Assay category: BCell
Result: Positive