Reference: Joseph R Podojil; Mahesh V Padval; Stephen D Miller. "Combination treatment of mice with CRx-153 (nortriptyline and desloratadine) decreases the severity of experimental autoimmune encephalomyelitis." Cellular immunology (2011).

Epitope: PLP<sub>178-191</sub>
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSK
Position: 179-192
Source molecule (GenBank): CAA30184.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP<sub>178-191</sub>
Chemical type: Peptide from protein
Sequence: NTWTTCQSIAFPSK
Position: 179-192
Source molecule (GenBank): CAA30184.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>84-104</sub>
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTPPPSQGKGR
Position: 111-131
Source molecule (GenBank): AAB59711.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MBP<sub>84-104</sub>
Chemical type: Peptide from protein
Sequence: VHFFKNIVTPRTPPPSQGKGR
Position: 111-131
Source molecule (GenBank): AAB59711.1
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks

Epitope: PLP 139-151
Chemical type: Peptide, no natural source
Sequence: HSLGKWLGHPDKF
Assay category: TCell
Result: Positive
Host: F 6-7 weeks