Reference: Victoria A Brentville; Peter Symonds; Katherine W Cook; Ian Daniels; Tracy Pitt; Mohamed Gijon; Poonam Vaghela; Wei Xue; Sabaria Shah; Rachael L Metheringham; Lindy G Durrant. "T cell repertoire to citrullinated self-peptides in healthy humans is not confined to the HLA-DR SE alleles; Targeting of citrullinated self-peptides presented by HLA-DP4 for tumour therapy." Oncoimmunology (2019).

Epitope: Vim 28-49 cit
Chemical type: Peptide from protein
Sequence: RSYVTTSTRTYSLGSALRPSTS
Position: 28-49
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  20-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Vim 28-49 cit
Chemical type: Peptide from protein
Sequence: RSYVTTSTRTYSLGSALRPSTS
Position: 28-49
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 28-49 cit
Chemical type: Peptide from protein
Sequence: RSYVTTSTRTYSLGSALRPSTS
Position: 28-49
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: Vim 28-49 cit
Chemical type: Peptide from protein
Sequence: RSYVTTSTRTYSLGSALRPSTS
Position: 28-49
Source molecule (GenBank): P08670.4
Assay category: MhcBinding
Result: Positive

Epitope: Vim 415-433 cit
Chemical type: Peptide from protein
Sequence: LPNFSSLNLRETNLDSLPL
Position: 415-433
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: Vim 415-433 cit
Chemical type: Peptide from protein
Sequence: LPNFSSLNLRETNLDSLPL
Position: 415-433
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  20-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Vim 415-433 cit
Chemical type: Peptide from protein
Sequence: LPNFSSLNLRETNLDSLPL
Position: 415-433
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 415-433 cit
Chemical type: Peptide from protein
Sequence: LPNFSSLNLRETNLDSLPL
Position: 415-433
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 415-433 cit
Chemical type: Peptide from protein
Sequence: LPNFSSLNLRETNLDSLPL
Position: 415-433
Source molecule (GenBank): P08670.4
Assay category: MhcBinding
Result: Positive

Epitope: Eno 241-260 cit
Chemical type: Peptide from protein
Sequence: VIGMDVAASEFFRSGKYDLD
Position: 241-260
Source molecule (GenBank): P06733.2
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Eno 241-260 cit
Chemical type: Peptide from protein
Sequence: VIGMDVAASEFFRSGKYDLD
Position: 241-260
Source molecule (GenBank): P06733.2
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Eno 241-260 cit
Chemical type: Peptide from protein
Sequence: VIGMDVAASEFFRSGKYDLD
Position: 241-260
Source molecule (GenBank): P06733.2
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: Eno 241-260 cit
Chemical type: Peptide from protein
Sequence: VIGMDVAASEFFRSGKYDLD
Position: 241-260
Source molecule (GenBank): P06733.2
Assay category: TCell
Result: Positive
Host:  20-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Eno 241-260 cit
Chemical type: Peptide from protein
Sequence: VIGMDVAASEFFRSGKYDLD
Position: 241-260
Source molecule (GenBank): P06733.2
Assay category: MhcBinding
Result: Positive

Epitope: Vim 28-42 cit
Chemical type: Peptide from protein
Sequence: RSYVTTSTRTYSLGS
Position: 28-42
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 418-431 cit
Chemical type: Peptide from protein
Sequence: FSSLNLRETNLDSL
Position: 418-431
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Eno 241-255 cit
Chemical type: Peptide from protein
Sequence: VIGMDVAASEFFRSG
Position: 241-255
Source molecule (GenBank): P06733.2
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 28-49 wt
Chemical type: Peptide from protein
Sequence: RSYVTTSTRTYSLGSALRPSTS
Position: 28-49
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: Vim 28-49 wt
Chemical type: Peptide from protein
Sequence: RSYVTTSTRTYSLGSALRPSTS
Position: 28-49
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive-Low
Host:  20-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Vim 28-49 wt
Chemical type: Peptide from protein
Sequence: RSYVTTSTRTYSLGSALRPSTS
Position: 28-49
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 28-49 wt
Chemical type: Peptide from protein
Sequence: RSYVTTSTRTYSLGSALRPSTS
Position: 28-49
Source molecule (GenBank): P08670.4
Assay category: MhcBinding
Result: Positive-Low

Epitope: Vim 415-433 wt
Chemical type: Peptide from protein
Sequence: LPNFSSLNLRETNLDSLPL
Position: 415-433
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive-Low
Host:  20-60 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Vim 415-433 wt
Chemical type: Peptide from protein
Sequence: LPNFSSLNLRETNLDSLPL
Position: 415-433
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive-Low
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 415-433 wt
Chemical type: Peptide from protein
Sequence: LPNFSSLNLRETNLDSLPL
Position: 415-433
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: Vim 415-433 wt
Chemical type: Peptide from protein
Sequence: LPNFSSLNLRETNLDSLPL
Position: 415-433
Source molecule (GenBank): P08670.4
Assay category: MhcBinding
Result: Positive-Low

Epitope: mo Vim 415-433 cit
Chemical type: Peptide from protein
Sequence: LPTFSSLNLRETNLESLPL
Position: 415-433
Source molecule (GenBank): P20152.3
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: mo Vim 415-433 cit
Chemical type: Peptide from protein
Sequence: LPTFSSLNLRETNLESLPL
Position: 415-433
Source molecule (GenBank): P20152.3
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mo Vim 415-433 cit
Chemical type: Peptide from protein
Sequence: LPTFSSLNLRETNLESLPL
Position: 415-433
Source molecule (GenBank): P20152.3
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mo Vim 415-433 wt
Chemical type: Peptide from protein
Sequence: LPTFSSLNLRETNLESLPL
Position: 415-433
Source molecule (GenBank): P20152.3
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mo Vim 415-433 wt
Chemical type: Peptide from protein
Sequence: LPTFSSLNLRETNLESLPL
Position: 415-433
Source molecule (GenBank): P20152.3
Assay category: TCell
Result: Negative
Host:  8-12 weeks

Epitope: mo Eno 241-260 cit
Chemical type: Peptide from protein
Sequence: VIGMDVAASEFYRSGKYDLD
Position: 241-260
Source molecule (GenBank): P17182.3
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mo Eno 241-260 cit
Chemical type: Peptide from protein
Sequence: VIGMDVAASEFYRSGKYDLD
Position: 241-260
Source molecule (GenBank): P17182.3
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: mo Eno 241-260 cit
Chemical type: Peptide from protein
Sequence: VIGMDVAASEFYRSGKYDLD
Position: 241-260
Source molecule (GenBank): P17182.3
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mo Eno 241-260 wt
Chemical type: Peptide from protein
Sequence: VIGMDVAASEFYRSGKYDLD
Position: 241-260
Source molecule (GenBank): P17182.3
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: mo Eno 241-260 wt
Chemical type: Peptide from protein
Sequence: VIGMDVAASEFYRSGKYDLD
Position: 241-260
Source molecule (GenBank): P17182.3
Assay category: TCell
Result: Negative
Host:  8-12 weeks

Epitope: collagen II 1236-1249 cit
Chemical type: Peptide from protein
Sequence: LQYMRADQAAGGLR
Position: 1236-1249
Source molecule (GenBank): P02458.3
Assay category: MhcBinding
Result: Negative

Epitope: Hep B peptide
Chemical type: Peptide from protein
Sequence: FFLLTRILTI
Position: 182-191
Source molecule (GenBank): P03142.4
Assay category: MhcBinding
Result: Positive