Reference: Jin-Gen Xu; Huifeng Jia; Shi Chen; Jingyue Xu; Yifan Zhan; Haijia Yu; Wei Wang; Xi Kang; Xiaopei Cui; Yujie Feng; Xiaofang Chen; Wei Xu; Xianfei Pan; Xiaoyue Wei; Hui Li; Yanting Wang; Simin Xia; Xiaoyan Liu; Lixiang Yang; Yang He; Xiangyang Zhu. "Structural and functional insights into a novel pre-clinical-stage antibody targeting IL-17A for treatment of autoimmune diseases." International journal of biological macromolecules (2022).

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000402

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 11600000

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0667

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 27200000

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000142

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 5600000.0

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000404

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000602

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 37600000

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 14800000

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00524

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00348

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.78

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.81

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00273

Epitope: Epitope of HB0017 Fab on IL-17A
Chemical type: Discontinuous protein residues
Discontinuous residues: L49, I51, H52, N53, E80, D81, P82, E83, R84, Y85, S87, R124, P127, H128, F133
Source molecule (GenBank): Q16552.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0107