Reference: Preeti Sharma; Daniel T Harris; Jennifer D Stone; David M Kranz. "T-cell Receptors Engineered  for Peptide Specificity Can Mediate Optimal T-cell Activity without Self Cross-Reactivity." Cancer immunology research (2019).

Epitope: MART-1 (26-35) analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Engineered

Epitope: MART-1 (26-35) analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Engineered

Epitope: MART-1 (26-35) analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Engineered

Epitope: MART-1 (26-35) analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Engineered

Epitope: MART-1 (26-35) analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Engineered

Epitope: MART-1 (26-35) analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 2.0

Epitope: MART-1 (26-35) analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 2.0

Epitope: MART-1 (26-35) analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Engineered

Epitope: MART-1 (26-35) analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTV
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Engineered

Epitope: MART-1 (26-35) E1D analog
Chemical type: Peptide, no natural source
Sequence: DLAGIGILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 10.0

Epitope: MART-1 (26-35) E1D analog
Chemical type: Peptide, no natural source
Sequence: DLAGIGILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 1000.0

Epitope: MART-1 (26-35) L2I analog
Chemical type: Peptide, no natural source
Sequence: EIAGIGILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 100.0

Epitope: MART-1 (26-35) L2I analog
Chemical type: Peptide, no natural source
Sequence: EIAGIGILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 1000.0

Epitope: MART-1 (26-35) A3G analog
Chemical type: Peptide, no natural source
Sequence: ELGGIGILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 1000.0

Epitope: MART-1 (26-35) A3G analog
Chemical type: Peptide, no natural source
Sequence: ELGGIGILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 1000.0

Epitope: MART-1 (26-35) I7L analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGLLTV
Assay category: TCell
Result: Positive
Quantitative measurement: 100.0

Epitope: MART-1 (26-35) I7L analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGLLTV
Assay category: TCell
Result: Positive
Quantitative measurement: 1000.0

Epitope: MART-1 (26-35) L8I analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGIITV
Assay category: TCell
Result: Positive
Quantitative measurement: 100.0

Epitope: MART-1 (26-35) L8I analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGIITV
Assay category: TCell
Result: Positive
Quantitative measurement: 100.0

Epitope: MART-1 (26-35) T9S analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILSV
Assay category: TCell
Result: Positive
Quantitative measurement: 1000.0

Epitope: MART-1 (26-35) T9S analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILSV
Assay category: TCell
Result: Positive
Quantitative measurement: 1000.0

Epitope: MART-1 (26-35) V10I analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTI
Assay category: TCell
Result: Positive
Quantitative measurement: 1000.0

Epitope: MART-1 (26-35) V10I analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTI
Assay category: TCell
Result: Positive
Quantitative measurement: 1000.0

Epitope: MART-1 (26-35) E1A analog
Chemical type: Peptide, no natural source
Sequence: ALAGIGILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 10.0

Epitope: MART-1 (26-35) E1A analog
Chemical type: Peptide, no natural source
Sequence: ALAGIGILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 100.0

Epitope: MART-1 (26-35) G4A analog
Chemical type: Peptide, no natural source
Sequence: ELAAIGILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 100.0

Epitope: MART-1 (26-35) G4A analog
Chemical type: Peptide, no natural source
Sequence: ELAAIGILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 1000.0

Epitope: MART-1 (26-35) G6A analog
Chemical type: Peptide, no natural source
Sequence: ELAGIAILTV
Assay category: TCell
Result: Positive
Quantitative measurement: 1000.0

Epitope: MART-1 (26-35) L8A analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGIATV
Assay category: TCell
Result: Positive
Quantitative measurement: 1000.0

Epitope: MART-1 (26-35) T9A analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILAV
Assay category: TCell
Result: Positive
Quantitative measurement: 100.0

Epitope: MART-1 (26-35) T9A analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILAV
Assay category: TCell
Result: Positive
Quantitative measurement: 100.0

Epitope: MART-1 (26-35) V10A analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTA
Assay category: TCell
Result: Positive
Quantitative measurement: 100.0

Epitope: MART-1 (26-35) V10A analog
Chemical type: Peptide, no natural source
Sequence: ELAGIGILTA
Assay category: TCell
Result: Positive
Quantitative measurement: 100.0

Epitope: ILLGIGIYAL
Chemical type: Peptide from protein
Sequence: ILLGIGIYAL
Position: 61-70
Source molecule (GenBank): NP_001008740.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: LLLGIGILVL
Chemical type: Peptide from protein
Sequence: LLLGIGILVL
Position: 22-31
Source molecule (GenBank): Q10589.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: FLKGIGWIPI
Chemical type: Peptide from protein
Sequence: FLKGIGWIPI
Position: 1443-1452
Source molecule (GenBank): P20929.5
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: ILEGIGILSV
Chemical type: Peptide from protein
Sequence: ILEGIGILSV
Position: 773-782
Source molecule (GenBank): NP_001273544.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: ILEGIGILAV
Chemical type: Peptide from protein
Sequence: ILEGIGILAV
Position: 815-824
Source molecule (GenBank): Q9BYT9.2
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: GLGIGIASM
Chemical type: Peptide from protein
Sequence: GLGIGIASM
Position: 182-190
Source molecule (GenBank): Q96QE2.3
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: DIAGIGLKTV
Chemical type: Peptide from protein
Sequence: DIAGIGLKTV
Position: 90-99
Source molecule (GenBank): AAI36593.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: ALGIGVYPV
Chemical type: Peptide from protein
Sequence: ALGIGVYPV
Position: 990-998
Source molecule (GenBank): O00562.4
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: ALGIGIYSL
Chemical type: Peptide from protein
Sequence: ALGIGIYSL
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: LLGIGIYAL
Chemical type: Peptide from protein
Sequence: LLGIGIYAL
Position: 62-70
Source molecule (GenBank): NP_001008740.1
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: ALGIGAVPI
Chemical type: Peptide from protein
Sequence: ALGIGAVPI
Position: 12-20
Source molecule (GenBank): Q53XC6.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: LLGIGILVL
Chemical type: Peptide from protein
Sequence: LLGIGILVL
Position: 23-31
Source molecule (GenBank): Q10589.1
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: AIGIGAYLV
Chemical type: Peptide from protein
Sequence: AIGIGAYLV
Position: 1935-1943
Source molecule (GenBank): O00763.3
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: LIGIGLNLV
Chemical type: Peptide from protein
Sequence: LIGIGLNLV
Position: 721-729
Source molecule (GenBank): Q96JI7.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: KMGIGWKPL
Chemical type: Peptide from protein
Sequence: KMGIGWKPL
Position: 793-801
Source molecule (GenBank): A6NGG8.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: KLGIGFAKA
Chemical type: Peptide from protein
Sequence: KLGIGFAKA
Position: 830-838
Source molecule (GenBank): AAA75557.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: LIGIGVITI
Chemical type: Peptide from protein
Sequence: LGIGVITI
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LIGIGVITI
Chemical type: Peptide from protein
Sequence: LGIGVITI
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: GLGIGALVL
Chemical type: Peptide from protein
Sequence: GLGIGALVL
Position: 61-69
Source molecule (GenBank): Q9Y2R0.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: HIGIGLLSL
Chemical type: Peptide from protein
Sequence: HIGIGLLSL
Position: 1051-1059
Source molecule (GenBank): AAI12170.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: GIGIGSGQL
Chemical type: Peptide from protein
Sequence: GIGIGSGQL
Position: 158-166
Source molecule (GenBank): Q9H201.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: MART-1 (26-35)
Chemical type: Peptide from protein
Sequence: EAAGIGILTV
Position: 26-35
Source molecule (GenBank): U06654
Assay category: TCell
Result: Positive
Quantitative measurement: 100.0

Epitope: MART-1 (26-35)
Chemical type: Peptide from protein
Sequence: EAAGIGILTV
Position: 26-35
Source molecule (GenBank): U06654
Assay category: TCell
Result: Positive
Quantitative measurement: 100.0