Reference: Salvatore G De-Simone; Paloma Napoleão-Pêgo; Priscila S Gonçalves; Guilherme C Lechuga; Arnaldo Mandonado; Carlos Graeff-Teixeira; David W Provance. "an Atypical Presenilin: Epitope Mapping, Characterization, and Development of an ELISA Peptide Assay for Specific Diagnostic of Angiostrongyliasis." Membranes (2022).

Epitope: Aspartyl Protease 1-15
Chemical type: Peptide from protein
Sequence: IHGRFVMEDGSGSNT
Position: 1-15
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 6-20
Chemical type: Peptide from protein
Sequence: VMEDGSGSNTDLKQE
Position: 6-20
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 11-25
Chemical type: Peptide from protein
Sequence: SGSNTDLKQEVKTVN
Position: 11-25
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 21-35
Chemical type: Peptide from protein
Sequence: VKTVNDETASKSKER
Position: 21-35
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 26-40
Chemical type: Peptide from protein
Sequence: DETASKSKERTISTT
Position: 26-40
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 31-45
Chemical type: Peptide from protein
Sequence: KSKERTISTTARNSK
Position: 31-45
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: PsAg1
Chemical type: Peptide from protein
Sequence: TISTTARNSKAASTN
Position: 36-50
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 41-55
Chemical type: Peptide from protein
Sequence: ARNSKAASTNGISEK
Position: 41-55
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 46-60
Chemical type: Peptide from protein
Sequence: AASTNGISEKVKRLY
Position: 46-60
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 56-70
Chemical type: Peptide from protein
Sequence: VKRLYGPTDMVKVFV
Position: 56-70
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 61-75
Chemical type: Peptide from protein
Sequence: GPTDMVKVFVPVSIT
Position: 61-75
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 66-80
Chemical type: Peptide from protein
Sequence: VKVFVPVSITMFIVV
Position: 66-80
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 71-85
Chemical type: Peptide from protein
Sequence: PVSITMFIVVTCVRN
Position: 71-85
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 76-90
Chemical type: Peptide from protein
Sequence: MFIVVTCVRNFDIYH
Position: 76-90
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 81-95
Chemical type: Peptide from protein
Sequence: TCVRNFDIYHGVNLI
Position: 81-95
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 96-110
Chemical type: Peptide from protein
Sequence: PTPYVIYNEPAADPG
Position: 96-110
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 101-115
Chemical type: Peptide from protein
Sequence: IYNEPAADPGTKLLH
Position: 101-115
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 106-120
Chemical type: Peptide from protein
Sequence: AADPGTKLLHAVANA
Position: 106-120
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: PsAg4
Chemical type: Peptide from protein
Sequence: TKLLHA
Position: 111-116
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 116-130
Chemical type: Peptide from protein
Sequence: AVANAATFLVVVAIS
Position: 116-130
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 121-135
Chemical type: Peptide from protein
Sequence: ATFLVVVAISTFALL
Position: 121-135
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 126-140
Chemical type: Peptide from protein
Sequence: VVAISTFALLCLFYY
Position: 126-140
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 136-150
Chemical type: Peptide from protein
Sequence: CLFYYKFYCFLTGFI
Position: 136-150
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 141-155
Chemical type: Peptide from protein
Sequence: KFYCFLTGFIMFSTF
Position: 141-155
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 146-160
Chemical type: Peptide from protein
Sequence: LTGFIMFSTFLLVSL
Position: 146-160
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 151-165
Chemical type: Peptide from protein
Sequence: MFSTFLLVSLFSFVQ
Position: 151-165
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 156-170
Chemical type: Peptide from protein
Sequence: LLVSLFSFVQYQQIL
Position: 156-170
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 161-175
Chemical type: Peptide from protein
Sequence: FSFVQYQQILSDLNV
Position: 161-175
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 166-180
Chemical type: Peptide from protein
Sequence: YQQILSDLNVPVSIV
Position: 166-180
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 171-185
Chemical type: Peptide from protein
Sequence: SDLNVPVSIVFIGFL
Position: 171-185
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 176-190
Chemical type: Peptide from protein
Sequence: PVSIVFIGFLHINLS
Position: 176-190
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 186-200
Chemical type: Peptide from protein
Sequence: HINLSAIELMSIFWK
Position: 186-200
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 191-205
Chemical type: Peptide from protein
Sequence: AIELMSIFWKGPMRL
Position: 191-205
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: PsAg6
Chemical type: Peptide from protein
Sequence: SIFWKGPMRLQQASL
Position: 196-210
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 201-215
Chemical type: Peptide from protein
Sequence: GPMRLQQASLILIAV
Position: 201-215
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 211-225
Chemical type: Peptide from protein
Sequence: ILIAVTVTLTIMQIL
Position: 211-225
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: PsAg7
Chemical type: Peptide from protein
Sequence: PQWTS
Position: 226-230
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 221-235
Chemical type: Peptide from protein
Sequence: IMQILPQWTSWALLV
Position: 221-235
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 226-240
Chemical type: Peptide from protein
Sequence: PQWTSWALLVTLALW
Position: 226-240
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 231-245
Chemical type: Peptide from protein
Sequence: WALLVTLALWDLFAV
Position: 231-245
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 236-250
Chemical type: Peptide from protein
Sequence: TLALWDLFAVLTPCG
Position: 236-250
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 241-255
Chemical type: Peptide from protein
Sequence: DLFAVLTPCGPLKLL
Position: 241-255
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 246-260
Chemical type: Peptide from protein
Sequence: LTPCGPLKLLVETAE
Position: 246-260
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 251-265
Chemical type: Peptide from protein
Sequence: PLKLLVETAEERGED
Position: 251-265
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 256-270
Chemical type: Peptide from protein
Sequence: VETAEERGEDLMPAI
Position: 256-270
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 261-275
Chemical type: Peptide from protein
Sequence: ERGEDLMPAIIYTGS
Position: 261-275
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 266-280
Chemical type: Peptide from protein
Sequence: LMPAIIYTGSASLPQ
Position: 266-280
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 271-285
Chemical type: Peptide from protein
Sequence: IYTGSASLPQSDSIE
Position: 271-285
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 276-290
Chemical type: Peptide from protein
Sequence: ASLPQSDSIESRRTS
Position: 276-290
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 286-300
Chemical type: Peptide from protein
Sequence: SRRTSEVKECTPVQD
Position: 286-300
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 291-305
Chemical type: Peptide from protein
Sequence: EVKECTPVQDKVKSV
Position: 291-305
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 296-310
Chemical type: Peptide from protein
Sequence: TPVQDKVKSVPSSGR
Position: 296-310
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 301-315
Chemical type: Peptide from protein
Sequence: KVKSVPSSGRFIESF
Position: 301-315
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: PsAg8
Chemical type: Peptide from protein
Sequence: PSSGRFIESFRMPSL
Position: 306-320
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 311-325
Chemical type: Peptide from protein
Sequence: FIESFRMPSLKSNDD
Position: 311-325
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 316-330
Chemical type: Peptide from protein
Sequence: RMPSLKSNDDERNIR
Position: 316-330
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 321-335
Chemical type: Peptide from protein
Sequence: KSNDDERNIRLGLGD
Position: 321-335
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: PsAg9
Chemical type: Peptide from protein
Sequence: ERNIRLGLG
Position: 326-334
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 336-350
Chemical type: Peptide from protein
Sequence: FIFYSLLVGTASTHG
Position: 336-350
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 341-355
Chemical type: Peptide from protein
Sequence: LLVGTASTHGDWATT
Position: 341-355
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 346-360
Chemical type: Peptide from protein
Sequence: ASTHGDWATTLALFR
Position: 346-360
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 351-365
Chemical type: Peptide from protein
Sequence: DWATTLALFRVYLNR
Position: 351-365
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 356-370
Chemical type: Peptide from protein
Sequence: LALFRVYLNRSWFHS
Position: 356-370
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 361-375
Chemical type: Peptide from protein
Sequence: VYLNRSWFHSCSPSS
Position: 361-375
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 371-385
Chemical type: Peptide from protein
Sequence: CSPSSTSKGTASTTN
Position: 371-385
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: PsAg11
Chemical type: Peptide from protein
Sequence: TSKGTASTTNIRHIW
Position: 376-390
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 381-395
Chemical type: Peptide from protein
Sequence: ASTTNIRHIWCDRYF
Position: 381-395
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Negative

Epitope: Aspartyl Protease 386-400
Chemical type: Peptide from protein
Sequence: IRHIWCDRYFSSRFA
Position: 386-400
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: Aspartyl Protease 401-415
Chemical type: Peptide from protein
Sequence: MSKFAVELNRKQIFI
Position: 401-415
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive

Epitope: PsAg2
Chemical type: Peptide from protein
Sequence: VKRLYGPTDM
Position: 56-65
Source molecule (GenBank): CAR63640.1
Assay category: BCell
Result: Positive