Reference: Benjamine Arellano; Rehana Hussain; William A Miller-Little; Emily Herndon; Doris Lambracht-Washington; Todd N Eagar; Robert Lewis; Don Healey; Steven Vernino; Benjamin M Greenberg; Olaf Stüve. "A Single Amino Acid Substitution Prevents Recognition of a Dominant Human Aquaporin-4 Determinant in the Context of HLA-DRB1*03:01 by a Murine TCR." PloS one (2016).

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: BCell
Result: Positive
Host: F 8-12 weeks

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: BCell
Result: Positive
Host: F 8-12 weeks

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: BCell
Result: Positive
Host: F 8-12 weeks

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: BCell
Result: Positive
Host: F 8-12 weeks

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: BCell
Result: Negative
Host: F 8-12 weeks

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: BCell
Result: Negative
Host: F 8-12 weeks

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: hAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETDDLILKPGVVH
Position: 281-300
Source molecule (GenBank): P55087.2
Assay category: MhcBinding
Result: Positive

Epitope: mAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETEDLILKPGVVH
Position: 281-300
Source molecule (GenBank): NP_033830.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: mAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETEDLILKPGVVH
Position: 281-300
Source molecule (GenBank): NP_033830.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: mAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETEDLILKPGVVH
Position: 281-300
Source molecule (GenBank): NP_033830.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: mAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETEDLILKPGVVH
Position: 281-300
Source molecule (GenBank): NP_033830.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: mAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETEDLILKPGVVH
Position: 281-300
Source molecule (GenBank): NP_033830.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks

Epitope: mAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETEDLILKPGVVH
Position: 281-300
Source molecule (GenBank): NP_033830.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks

Epitope: mAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETEDLILKPGVVH
Position: 281-300
Source molecule (GenBank): NP_033830.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: mAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETEDLILKPGVVH
Position: 281-300
Source molecule (GenBank): NP_033830.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: mAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETEDLILKPGVVH
Position: 281-300
Source molecule (GenBank): NP_033830.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: mAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETEDLILKPGVVH
Position: 281-300
Source molecule (GenBank): NP_033830.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: mAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETEDLILKPGVVH
Position: 281-300
Source molecule (GenBank): NP_033830.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: mAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETEDLILKPGVVH
Position: 281-300
Source molecule (GenBank): NP_033830.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: mAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETEDLILKPGVVH
Position: 281-300
Source molecule (GenBank): NP_033830.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: mAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETEDLILKPGVVH
Position: 281-300
Source molecule (GenBank): NP_033830.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: mAQP4 (281-300)
Chemical type: Peptide from protein
Sequence: EDNRSQVETEDLILKPGVVH
Position: 281-300
Source molecule (GenBank): NP_033830.2
Assay category: MhcBinding
Result: Positive

Epitope: PLP (91-110)
Chemical type: Peptide from protein
Sequence: YTTGAVRQIFGDYKTTICGK
Position: 92-111
Source molecule (GenBank): CAA30184.1
Assay category: TCell
Result: Positive
Host: F 8-12 weeks

Epitope: hAQP4 (284-299)
Chemical type: Peptide from protein
Sequence: RSQVETDDLILKPGVV
Position: 284-299
Source molecule (GenBank): P55087.2
Assay category: BCell
Result: Positive
Host: F 8-12 weeks

Epitope: hAQP4 (284-299)
Chemical type: Peptide from protein
Sequence: RSQVETDDLILKPGVV
Position: 284-299
Source molecule (GenBank): P55087.2
Assay category: BCell
Result: Negative
Host: F 8-12 weeks

Epitope: hAQP4 (284-299)
Chemical type: Peptide from protein
Sequence: RSQVETDDLILKPGVV
Position: 284-299
Source molecule (GenBank): P55087.2
Assay category: MhcBinding
Result: Positive