Reference: James E Stefano; Dana M Lord; Yanfeng Zhou; Julie Jaworski; Joern Hopke; Tara Travaline; Ningning Zhang; Karen Wong; Amanda Lennon; Timothy He; Eva Bric-Furlong; Cornishia Cherrie; Tristan Magnay; Elisabeth Remy; William Brondyk; Huawei Qiu; Katarina Radošević. "A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms." The Journal of biological chemistry (2020).

Epitope: Epitope of TB19 Fab on CD73
Chemical type: Discontinuous protein residues
Discontinuous residues: N122, G123, V124, E125, K147, P149, P182, F183, S185, N186, P187, G188, T189, N190, L191, V192, F193, E194, R374, R517, D522
Source molecule (GenBank): P21589.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.25

Epitope: Epitope of TB19 Fab on CD73
Chemical type: Discontinuous protein residues
Discontinuous residues: N122, G123, V124, E125, K147, P149, P182, F183, S185, N186, P187, G188, T189, N190, L191, V192, F193, E194, R374, R517, D522
Source molecule (GenBank): P21589.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of TB19 Fab on CD73
Chemical type: Discontinuous protein residues
Discontinuous residues: N122, G123, V124, E125, K147, P149, P182, F183, S185, N186, P187, G188, T189, N190, L191, V192, F193, E194, R374, R517, D522
Source molecule (GenBank): P21589.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.18

Epitope: Epitope of TB19 Fab on CD73
Chemical type: Discontinuous protein residues
Discontinuous residues: N122, G123, V124, E125, K147, P149, P182, F183, S185, N186, P187, G188, T189, N190, L191, V192, F193, E194, R374, R517, D522
Source molecule (GenBank): P21589.1
Assay category: BCell
Result: Positive
Quantitative measurement: 165000.0

Epitope: Epitope of TB19 Fab on CD73
Chemical type: Discontinuous protein residues
Discontinuous residues: N122, G123, V124, E125, K147, P149, P182, F183, S185, N186, P187, G188, T189, N190, L191, V192, F193, E194, R374, R517, D522
Source molecule (GenBank): P21589.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00069

Epitope: Epitope of TB38 Fab on CD73
Chemical type: Discontinuous protein residues
Discontinuous residues: K145, A146, K147, A151, S152, S155, G156, L159, P160, Y161, K162, V163, P202, E203, K206, T209, L210, N211
Source molecule (GenBank): P21589.1
Assay category: BCell
Result: Positive
Quantitative measurement: 184000.0

Epitope: Epitope of TB38 Fab on CD73
Chemical type: Discontinuous protein residues
Discontinuous residues: K145, A146, K147, A151, S152, S155, G156, L159, P160, Y161, K162, V163, P202, E203, K206, T209, L210, N211
Source molecule (GenBank): P21589.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000102

Epitope: Epitope of TB38 Fab on CD73
Chemical type: Discontinuous protein residues
Discontinuous residues: K145, A146, K147, A151, S152, S155, G156, L159, P160, Y161, K162, V163, P202, E203, K206, T209, L210, N211
Source molecule (GenBank): P21589.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.73

Epitope: Epitope of TB38 Fab on CD73
Chemical type: Discontinuous protein residues
Discontinuous residues: K145, A146, K147, A151, S152, S155, G156, L159, P160, Y161, K162, V163, P202, E203, K206, T209, L210, N211
Source molecule (GenBank): P21589.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of TB38 Fab on CD73
Chemical type: Discontinuous protein residues
Discontinuous residues: K145, A146, K147, A151, S152, S155, G156, L159, P160, Y161, K162, V163, P202, E203, K206, T209, L210, N211
Source molecule (GenBank): P21589.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.814