Reference: Hidefumi Inaba; William Martin; Matt Ardito; Anne Searls De Groot; Leslie J De Groot. "The role of glutamic or aspartic acid in position four of the epitope binding motif and thyrotropin receptor-extracellular domain epitope selection in Graves' disease." The Journal of clinical endocrinology and metabolism (2010).

Epitope: TSHR-ECD 20-35 No.1
Chemical type: Peptide from protein
Sequence: GGMGCSSPPCECHQEE
Position: 20-35
Source molecule (GenBank): AAI27629.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 20-35 No.1
Chemical type: Peptide from protein
Sequence: GGMGCSSPPCECHQEE
Position: 20-35
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 20-35 No.1
Chemical type: Peptide from protein
Sequence: GGMGCSSPPCECHQEE
Position: 20-35
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 65000.0

Epitope: TSHR-ECD 20-35 No.1
Chemical type: Peptide from protein
Sequence: GGMGCSSPPCECHQEE
Position: 20-35
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 30-49 No.2
Chemical type: Peptide from protein
Sequence: ECHQEEDFRVTCKDIQRIPS
Position: 30-49
Source molecule (GenBank): AAI27629.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 30-49 No.2
Chemical type: Peptide from protein
Sequence: ECHQEEDFRVTCKDIQRIPS
Position: 30-49
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 30-49 No.2
Chemical type: Peptide from protein
Sequence: ECHQEEDFRVTCKDIQRIPS
Position: 30-49
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 80000.0

Epitope: TSHR-ECD 30-49 No.2
Chemical type: Peptide from protein
Sequence: ECHQEEDFRVTCKDIQRIPS
Position: 30-49
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 44-62 No.3
Chemical type: Peptide from protein
Sequence: IQRIPSLPPSTQTLKLIET
Position: 44-62
Source molecule (GenBank): AAI27629.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 44-62 No.3
Chemical type: Peptide from protein
Sequence: IQRIPSLPPSTQTLKLIET
Position: 44-62
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 44-62 No.3
Chemical type: Peptide from protein
Sequence: IQRIPSLPPSTQTLKLIET
Position: 44-62
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2100.0

Epitope: TSHR-ECD 44-62 No.3
Chemical type: Peptide from protein
Sequence: IQRIPSLPPSTQTLKLIET
Position: 44-62
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 46500.0

Epitope: TSHR-ECD 57-75 No.4
Chemical type: Peptide from protein
Sequence: LKLIETHLRTIPSHAFSNL
Position: 57-75
Source molecule (GenBank): AAI27629.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 57-75 No.4
Chemical type: Peptide from protein
Sequence: LKLIETHLRTIPSHAFSNL
Position: 57-75
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 57-75 No.4
Chemical type: Peptide from protein
Sequence: LKLIETHLRTIPSHAFSNL
Position: 57-75
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 300.0

Epitope: TSHR-ECD 57-75 No.4
Chemical type: Peptide from protein
Sequence: LKLIETHLRTIPSHAFSNL
Position: 57-75
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 42500.0

Epitope: TSHR-ECD 70-88 No.5
Chemical type: Peptide from protein
Sequence: HAFSNLPNISRIYVSIDVT
Position: 70-88
Source molecule (GenBank): AAI27629.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 70-88 No.5
Chemical type: Peptide from protein
Sequence: HAFSNLPNISRIYVSIDVT
Position: 70-88
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 29000.0

Epitope: TSHR-ECD 70-88 No.5
Chemical type: Peptide from protein
Sequence: HAFSNLPNISRIYVSIDVT
Position: 70-88
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 1400.0

Epitope: TSHR-ECD 70-88 No.5
Chemical type: Peptide from protein
Sequence: HAFSNLPNISRIYVSIDVT
Position: 70-88
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 36300.0

Epitope: TSHR-ECD 83-102 No.6
Chemical type: Peptide from protein
Sequence: VSIDVTLQQLESHSFYNLSK
Position: 83-102
Source molecule (GenBank): AAI27629.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 83-102 No.6
Chemical type: Peptide from protein
Sequence: VSIDVTLQQLESHSFYNLSK
Position: 83-102
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 41600.0

Epitope: TSHR-ECD 83-102 No.6
Chemical type: Peptide from protein
Sequence: VSIDVTLQQLESHSFYNLSK
Position: 83-102
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 51000.0

Epitope: TSHR-ECD 83-102 No.6
Chemical type: Peptide from protein
Sequence: VSIDVTLQQLESHSFYNLSK
Position: 83-102
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 61300.0

Epitope: TSHR-ECD 97-112 No.7
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTR
Position: 97-112
Source molecule (GenBank): AAI27629.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 97-112 No.7
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTR
Position: 97-112
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 42000.0

Epitope: TSHR-ECD 97-112 No.7
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTR
Position: 97-112
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 900.0

Epitope: TSHR-ECD 97-112 No.7
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTR
Position: 97-112
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 42000.0

Epitope: TSHR-ECD 109-124 No.8
Chemical type: Peptide from protein
Sequence: RNTRNLTYIDPDALKE
Position: 109-124
Source molecule (GenBank): AAI27629.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 109-124 No.8
Chemical type: Peptide from protein
Sequence: RNTRNLTYIDPDALKE
Position: 109-124
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 109-124 No.8
Chemical type: Peptide from protein
Sequence: RNTRNLTYIDPDALKE
Position: 109-124
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 5500.0

Epitope: TSHR-ECD 109-124 No.8
Chemical type: Peptide from protein
Sequence: RNTRNLTYIDPDALKE
Position: 109-124
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 43300.0

Epitope: TSHR-ECD 132-150 No.10
Chemical type: Peptide from protein
Sequence: GIFNTGLKMFPDLTKVYST
Position: 132-150
Source molecule (GenBank): AAI27629.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 132-150 No.10
Chemical type: Peptide from protein
Sequence: GIFNTGLKMFPDLTKVYST
Position: 132-150
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 640.0

Epitope: TSHR-ECD 132-150 No.10
Chemical type: Peptide from protein
Sequence: GIFNTGLKMFPDLTKVYST
Position: 132-150
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 13000.0

Epitope: TSHR-ECD 132-150 No.10
Chemical type: Peptide from protein
Sequence: GIFNTGLKMFPDLTKVYST
Position: 132-150
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 43000.0

Epitope: TSHR-ECD 132-150 No.11
Chemical type: Peptide from protein
Sequence: TKVYSTDIFFILEITDNPY
Position: 145-163
Source molecule (GenBank): AAI27629.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 132-150 No.11
Chemical type: Peptide from protein
Sequence: TKVYSTDIFFILEITDNPY
Position: 145-163
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 19300.0

Epitope: TSHR-ECD 132-150 No.11
Chemical type: Peptide from protein
Sequence: TKVYSTDIFFILEITDNPY
Position: 145-163
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 10000.0

Epitope: TSHR-ECD 132-150 No.11
Chemical type: Peptide from protein
Sequence: TKVYSTDIFFILEITDNPY
Position: 145-163
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 15000.0

Epitope: TSHR-ECD 158-176 No.12
Chemical type: Peptide from protein
Sequence: ITDNPYMTSIPVNAFQGLC
Position: 158-176
Source molecule (GenBank): AAI27629.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 158-176 No.12
Chemical type: Peptide from protein
Sequence: ITDNPYMTSIPVNAFQGLC
Position: 158-176
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 50000.0

Epitope: TSHR-ECD 158-176 No.12
Chemical type: Peptide from protein
Sequence: ITDNPYMTSIPVNAFQGLC
Position: 158-176
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 16700.0

Epitope: TSHR-ECD 158-176 No.12
Chemical type: Peptide from protein
Sequence: ITDNPYMTSIPVNAFQGLC
Position: 158-176
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 28300.0

Epitope: TSHR-ECD 172-186 No.13
Chemical type: Peptide from protein
Sequence: FQGLCNETLTLKLYN
Position: 172-186
Source molecule (GenBank): AAI27629.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 172-186 No.13
Chemical type: Peptide from protein
Sequence: FQGLCNETLTLKLYN
Position: 172-186
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 18300.0

Epitope: TSHR-ECD 172-186 No.13
Chemical type: Peptide from protein
Sequence: FQGLCNETLTLKLYN
Position: 172-186
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 4300.0

Epitope: TSHR-ECD 172-186 No.13
Chemical type: Peptide from protein
Sequence: FQGLCNETLTLKLYN
Position: 172-186
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 12500.0

Epitope: TSHR-ECD 183-198 No.14
Chemical type: Peptide from protein
Sequence: KLYNNGFTSVQGYAFN
Position: 183-198
Source molecule (GenBank): AAI27629.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 183-198 No.14
Chemical type: Peptide from protein
Sequence: KLYNNGFTSVQGYAFN
Position: 183-198
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 183-198 No.14
Chemical type: Peptide from protein
Sequence: KLYNNGFTSVQGYAFN
Position: 183-198
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 800.0

Epitope: TSHR-ECD 183-198 No.14
Chemical type: Peptide from protein
Sequence: KLYNNGFTSVQGYAFN
Position: 183-198
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 55500.0

Epitope: TSHR-ECD 195-210 No.15
Chemical type: Peptide from protein
Sequence: YAFNGTKLDAVYLNKN
Position: 195-210
Source molecule (GenBank): AAI27629.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 195-210 No.15
Chemical type: Peptide from protein
Sequence: YAFNGTKLDAVYLNKN
Position: 195-210
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 46600.0

Epitope: TSHR-ECD 195-210 No.15
Chemical type: Peptide from protein
Sequence: YAFNGTKLDAVYLNKN
Position: 195-210
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 55000.0

Epitope: TSHR-ECD 195-210 No.15
Chemical type: Peptide from protein
Sequence: YAFNGTKLDAVYLNKN
Position: 195-210
Source molecule (GenBank): AAI27629.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 79800.0

Epitope: TSHR-ECD 217-232 No.17
Chemical type: Peptide from protein
Sequence: DKDAFGGVYSGPSLLD
Position: 217-232
Source molecule (GenBank): AAA36783.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 217-232 No.17
Chemical type: Peptide from protein
Sequence: DKDAFGGVYSGPSLLD
Position: 217-232
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 90000.0

Epitope: TSHR-ECD 217-232 No.17
Chemical type: Peptide from protein
Sequence: DKDAFGGVYSGPSLLD
Position: 217-232
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 28300.0

Epitope: TSHR-ECD 217-232 No.17
Chemical type: Peptide from protein
Sequence: DKDAFGGVYSGPSLLD
Position: 217-232
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 227-242 No.18
Chemical type: Peptide from protein
Sequence: GPSLLDVSQTSVTALP
Position: 227-242
Source molecule (GenBank): AAA36783.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 227-242 No.18
Chemical type: Peptide from protein
Sequence: GPSLLDVSQTSVTALP
Position: 227-242
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 45000.0

Epitope: TSHR-ECD 227-242 No.18
Chemical type: Peptide from protein
Sequence: GPSLLDVSQTSVTALP
Position: 227-242
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 1200.0

Epitope: TSHR-ECD 227-242 No.18
Chemical type: Peptide from protein
Sequence: GPSLLDVSQTSVTALP
Position: 227-242
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 41300.0

Epitope: TSHR-ECD 237-252 No.19
Chemical type: Peptide from protein
Sequence: SVTALPSKGLEHLKEL
Position: 237-252
Source molecule (GenBank): AAA36783.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 237-252 No.19
Chemical type: Peptide from protein
Sequence: SVTALPSKGLEHLKEL
Position: 237-252
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 237-252 No.19
Chemical type: Peptide from protein
Sequence: SVTALPSKGLEHLKEL
Position: 237-252
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 20000.0

Epitope: TSHR-ECD 237-252 No.19
Chemical type: Peptide from protein
Sequence: SVTALPSKGLEHLKEL
Position: 237-252
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 248-263 No.20
Chemical type: Peptide from protein
Sequence: HLKELIARNTWTLKKL
Position: 248-263
Source molecule (GenBank): AAA36783.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 248-263 No.20
Chemical type: Peptide from protein
Sequence: HLKELIARNTWTLKKL
Position: 248-263
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 50500.0

Epitope: TSHR-ECD 248-263 No.20
Chemical type: Peptide from protein
Sequence: HLKELIARNTWTLKKL
Position: 248-263
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 40000.0

Epitope: TSHR-ECD 248-263 No.20
Chemical type: Peptide from protein
Sequence: HLKELIARNTWTLKKL
Position: 248-263
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 31600.0

Epitope: TSHR-ECD 258-277 No.21
Chemical type: Peptide from protein
Sequence: WTLKKLPLSLSFLHLTRADL
Position: 258-277
Source molecule (GenBank): AAA36783.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 258-277 No.21
Chemical type: Peptide from protein
Sequence: WTLKKLPLSLSFLHLTRADL
Position: 258-277
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 16700.0

Epitope: TSHR-ECD 258-277 No.21
Chemical type: Peptide from protein
Sequence: WTLKKLPLSLSFLHLTRADL
Position: 258-277
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 4000.0

Epitope: TSHR-ECD 258-277 No.21
Chemical type: Peptide from protein
Sequence: WTLKKLPLSLSFLHLTRADL
Position: 258-277
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 38800.0

Epitope: TSHR-ECD 286-305 No.23
Chemical type: Peptide from protein
Sequence: FKNQKKIRGILESLMCNESS
Position: 286-305
Source molecule (GenBank): AAA36783.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 286-305 No.23
Chemical type: Peptide from protein
Sequence: FKNQKKIRGILESLMCNESS
Position: 286-305
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 60000.0

Epitope: TSHR-ECD 286-305 No.23
Chemical type: Peptide from protein
Sequence: FKNQKKIRGILESLMCNESS
Position: 286-305
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 46700.0

Epitope: TSHR-ECD 286-305 No.23
Chemical type: Peptide from protein
Sequence: FKNQKKIRGILESLMCNESS
Position: 286-305
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 21000.0

Epitope: TSHR-ECD 301-320 No.24
Chemical type: Peptide from protein
Sequence: CNESSMQSLRQRKSVNALNS
Position: 301-320
Source molecule (GenBank): AAA36783.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 301-320 No.24
Chemical type: Peptide from protein
Sequence: CNESSMQSLRQRKSVNALNS
Position: 301-320
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 46700.0

Epitope: TSHR-ECD 301-320 No.24
Chemical type: Peptide from protein
Sequence: CNESSMQSLRQRKSVNALNS
Position: 301-320
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 3000.0

Epitope: TSHR-ECD 301-320 No.24
Chemical type: Peptide from protein
Sequence: CNESSMQSLRQRKSVNALNS
Position: 301-320
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 52800.0

Epitope: TSHR-ECD 315-334 No.25
Chemical type: Peptide from protein
Sequence: VNALNSPLHQEYEENLGDSI
Position: 315-334
Source molecule (GenBank): AAA36783.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 315-334 No.25
Chemical type: Peptide from protein
Sequence: VNALNSPLHQEYEENLGDSI
Position: 315-334
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 33800.0

Epitope: TSHR-ECD 315-334 No.25
Chemical type: Peptide from protein
Sequence: VNALNSPLHQEYEENLGDSI
Position: 315-334
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 315-334 No.25
Chemical type: Peptide from protein
Sequence: VNALNSPLHQEYEENLGDSI
Position: 315-334
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 56800.0

Epitope: TSHR-ECD 329-348 No.26
Chemical type: Peptide from protein
Sequence: NLGDSIVGYKEKSKFQDTHN
Position: 329-348
Source molecule (GenBank): AAA36783.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 329-348 No.26
Chemical type: Peptide from protein
Sequence: NLGDSIVGYKEKSKFQDTHN
Position: 329-348
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 80000.0

Epitope: TSHR-ECD 329-348 No.26
Chemical type: Peptide from protein
Sequence: NLGDSIVGYKEKSKFQDTHN
Position: 329-348
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 70000.0

Epitope: TSHR-ECD 329-348 No.26
Chemical type: Peptide from protein
Sequence: NLGDSIVGYKEKSKFQDTHN
Position: 329-348
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 82500.0

Epitope: TSHR-ECD 343-362 No.27
Chemical type: Peptide from protein
Sequence: FQDTHNNAHYYVFFEEQEDE
Position: 343-362
Source molecule (GenBank): AAA36783.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 343-362 No.27
Chemical type: Peptide from protein
Sequence: FQDTHNNAHYYVFFEEQEDE
Position: 343-362
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 20000.0

Epitope: TSHR-ECD 343-362 No.27
Chemical type: Peptide from protein
Sequence: FQDTHNNAHYYVFFEEQEDE
Position: 343-362
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 36600.0

Epitope: TSHR-ECD 343-362 No.27
Chemical type: Peptide from protein
Sequence: FQDTHNNAHYYVFFEEQEDE
Position: 343-362
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 53000.0

Epitope: TSHR-ECD 357-376 No.28
Chemical type: Peptide from protein
Sequence: EEQEDEIIGFGQELKNPQEE
Position: 357-376
Source molecule (GenBank): AAA36783.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 357-376 No.28
Chemical type: Peptide from protein
Sequence: EEQEDEIIGFGQELKNPQEE
Position: 357-376
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 38300.0

Epitope: TSHR-ECD 357-376 No.28
Chemical type: Peptide from protein
Sequence: EEQEDEIIGFGQELKNPQEE
Position: 357-376
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 60000.0

Epitope: TSHR-ECD 357-376 No.28
Chemical type: Peptide from protein
Sequence: EEQEDEIIGFGQELKNPQEE
Position: 357-376
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 45000.0

Epitope: TSHR-ECD 371-390 No.29
Chemical type: Peptide from protein
Sequence: KNPQEETLQAFDSHYDYTIC
Position: 371-390
Source molecule (GenBank): AAA36783.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 371-390 No.29
Chemical type: Peptide from protein
Sequence: KNPQEETLQAFDSHYDYTIC
Position: 371-390
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 18300.0

Epitope: TSHR-ECD 371-390 No.29
Chemical type: Peptide from protein
Sequence: KNPQEETLQAFDSHYDYTIC
Position: 371-390
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 9300.0

Epitope: TSHR-ECD 371-390 No.29
Chemical type: Peptide from protein
Sequence: KNPQEETLQAFDSHYDYTIC
Position: 371-390
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 73300.0

Epitope: TSHR-ECD 385-404 No.30
Chemical type: Peptide from protein
Sequence: YDYTICGDSEDMVCTPKSDE
Position: 385-404
Source molecule (GenBank): AAA36783.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 385-404 No.30
Chemical type: Peptide from protein
Sequence: YDYTICGDSEDMVCTPKSDE
Position: 385-404
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 13000.0

Epitope: TSHR-ECD 385-404 No.30
Chemical type: Peptide from protein
Sequence: YDYTICGDSEDMVCTPKSDE
Position: 385-404
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 385-404 No.30
Chemical type: Peptide from protein
Sequence: YDYTICGDSEDMVCTPKSDE
Position: 385-404
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 399-418 No.31
Chemical type: Peptide from protein
Sequence: TPKSDEFNPCEDIMGYKFLR
Position: 399-418
Source molecule (GenBank): AAA36783.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: TSHR-ECD 399-418 No.31
Chemical type: Peptide from protein
Sequence: TPKSDEFNPCEDIMGYKFLR
Position: 399-418
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 399-418 No.31
Chemical type: Peptide from protein
Sequence: TPKSDEFNPCEDIMGYKFLR
Position: 399-418
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 80000.0

Epitope: TSHR-ECD 399-418 No.31
Chemical type: Peptide from protein
Sequence: TPKSDEFNPCEDIMGYKFLR
Position: 399-418
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 51800.0

Epitope: TSHR-ECD 105-118 No.32
Chemical type: Peptide from protein
Sequence: HIEIRNTRNLTYID
Position: 105-118
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 10000.0

Epitope: TSHR-ECD 105-118 No.32
Chemical type: Peptide from protein
Sequence: HIEIRNTRNLTYID
Position: 105-118
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 450.0

Epitope: TSHR-ECD 105-118 No.32
Chemical type: Peptide from protein
Sequence: HIEIRNTRNLTYID
Position: 105-118
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 10000.0

Epitope: TSHR-ECD 267-282 No.34
Chemical type: Peptide from protein
Sequence: LSFLHLTRADLSYPSHC
Position: 267-283
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 27600.0

Epitope: TSHR-ECD 267-282 No.34
Chemical type: Peptide from protein
Sequence: LSFLHLTRADLSYPSHC
Position: 267-283
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 600.0

Epitope: TSHR-ECD 267-282 No.34
Chemical type: Peptide from protein
Sequence: LSFLHLTRADLSYPSHC
Position: 267-283
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 376-389 No.36
Chemical type: Peptide from protein
Sequence: ETLQAFDSHYDYTI
Position: 376-389
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 25000.0

Epitope: TSHR-ECD 376-389 No.36
Chemical type: Peptide from protein
Sequence: ETLQAFDSHYDYTI
Position: 376-389
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 15700.0

Epitope: TSHR-ECD 376-389 No.36
Chemical type: Peptide from protein
Sequence: ETLQAFDSHYDYTI
Position: 376-389
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 78-94 No.37
Chemical type: Peptide from protein
Sequence: ISRIYVSIDVTLQQLES
Position: 78-94
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 300.0

Epitope: TSHR-ECD 78-94 No.37
Chemical type: Peptide from protein
Sequence: ISRIYVSIDVTLQQLES
Position: 78-94
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 42000.0

Epitope: TSHR-ECD 103-119 No.38
Chemical type: Peptide from protein
Sequence: VTHIEIRNTRNLTYIDP
Position: 103-119
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 17500.0

Epitope: TSHR-ECD 103-119 No.38
Chemical type: Peptide from protein
Sequence: VTHIEIRNTRNLTYIDP
Position: 103-119
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 4800.0

Epitope: TSHR-ECD 201-217 No.39
Chemical type: Peptide from protein
Sequence: KLDAVYLNKNKYLTVID
Position: 201-217
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 201-217 No.39
Chemical type: Peptide from protein
Sequence: KLDAVYLNKNKYLTVID
Position: 201-217
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 283-297 No.41
Chemical type: Peptide from protein
Sequence: CCAFKNQKKIRGILE
Position: 283-297
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: TSHR-ECD 283-297 No.41
Chemical type: Peptide from protein
Sequence: CCAFKNQKKIRGILE
Position: 283-297
Source molecule (GenBank): AAA36783.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: HSP 3-13 ex1
Chemical type: Peptide from protein
Sequence: KITAYDEEARR
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 300.0

Epitope: HA 307–319 ex2
Chemical type: Peptide from protein
Sequence: PKYVKQNTLKLAT
Position: 306-318
Source molecule (GenBank): 0704243A
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 600.0

Epitope: HA 307–319 ex2
Chemical type: Peptide from protein
Sequence: PKYVKQNTLKLAT
Position: 306-318
Source molecule (GenBank): 0704243A
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 360.0