Reference: M W Cunningham; S M Antone; M Smart; R Liu; S Kosanke. "Molecular analysis of human cardiac myosin-cross-reactive B- and T-cell epitopes of the group A streptococcal M5 protein." Infection and immunity (1997).

Epitope: NT1 p1-18
Chemical type: Peptide from protein
Sequence: AVTRGTINDPQRAKEALD
Position: 43-60
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: NT1 p1-18
Chemical type: Peptide from protein
Sequence: AVTRGTINDPQRAKEALD
Position: 43-60
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NT2 p14-31
Chemical type: Peptide from protein
Sequence: KEALDKYELENHDLKTKN
Position: 56-73
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: NT2 p14-31
Chemical type: Peptide from protein
Sequence: KEALDKYELENHDLKTKN
Position: 56-73
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NT3 p27-44
Chemical type: Peptide from protein
Sequence: LKTKNEGLKTENEGLKTE
Position: 69-86
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: NT3 p27-44
Chemical type: Peptide from protein
Sequence: LKTKNEGLKTENEGLKTE
Position: 69-86
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NT4 p40-58
Chemical type: Peptide from protein
Sequence: GLKTENEGLKTENEGLKTE
Position: 75-93
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: NT4 p40-58
Chemical type: Peptide from protein
Sequence: GLKTENEGLKTENEGLKTE
Position: 75-93
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NT6 p72-89
Chemical type: Peptide from protein
Sequence: QRDTLSTQKETLEREVQN
Position: 114-131
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: NT6 p72-89
Chemical type: Peptide from protein
Sequence: QRDTLSTQKETLEREVQN
Position: 114-131
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NT7 p85-102
Chemical type: Peptide from protein
Sequence: REVQNTQYNNETLKIKNG
Position: 127-144
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: NT7 p85-102
Chemical type: Peptide from protein
Sequence: REVQNTQYNNETLKIKNG
Position: 127-144
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: NT8 p98-115
Chemical type: Peptide from protein
Sequence: KIKNGDLTKELNKTRQEL
Position: 140-157
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: NT8 p98-115
Chemical type: Peptide from protein
Sequence: KIKNGDLTKELNKTRQEL
Position: 140-157
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B1A p111-129
Chemical type: Peptide from protein
Sequence: TRQELANKQQESKENEKAL
Position: 153-171
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: B1A p111-129
Chemical type: Peptide from protein
Sequence: TRQELANKQQESKENEKAL
Position: 153-171
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B1B p124-141
Chemical type: Peptide from protein
Sequence: ENEKALNELLEKTVKDKI
Position: 166-183
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: B1B p124-141
Chemical type: Peptide from protein
Sequence: ENEKALNELLEKTVKDKI
Position: 166-183
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B1B2 p137-154
Chemical type: Peptide from protein
Sequence: VKDKIAKEQENKETIGTL
Position: 179-196
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: B1B2 p137-154
Chemical type: Peptide from protein
Sequence: VKDKIAKEQENKETIGTL
Position: 179-196
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B2 p150-167
Chemical type: Peptide from protein
Sequence: TIGTLKKILDETVKDKIA
Position: 192-209
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: B2 p150-167
Chemical type: Peptide from protein
Sequence: TIGTLKKILDETVKDKIA
Position: 192-209
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B2B3A p163-180
Chemical type: Peptide from protein
Sequence: KDKIAKEQENKETIGTLK
Position: 180-197
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: B2B3A p163-180
Chemical type: Peptide from protein
Sequence: KDKIAKEQENKETIGTLK
Position: 180-197
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B3A p176-193
Chemical type: Peptide from protein
Sequence: IGTLKKILDETVKDKLAK
Position: 218-235
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: B3A p176-193
Chemical type: Peptide from protein
Sequence: IGTLKKILDETVKDKLAK
Position: 218-235
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B2B3B p189-206
Chemical type: Peptide from protein
Sequence: DKLAKEQKSKQNIGALKQ
Position: 231-248
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: B2B3B p189-206
Chemical type: Peptide from protein
Sequence: DKLAKEQKSKQNIGALKQ
Position: 231-248
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B3B p202-219
Chemical type: Peptide from protein
Sequence: GALKQELAKKDEANKISD
Position: 244-261
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: B3B p202-219
Chemical type: Peptide from protein
Sequence: GALKQELAKKDEANKISD
Position: 244-261
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: C1A p215-232
Chemical type: Peptide from protein
Sequence: NKISDASRKGLRRDLDAS
Position: 257-274
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: C1A p215-232
Chemical type: Peptide from protein
Sequence: NKISDASRKGLRRDLDAS
Position: 257-274
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: C1B p228-245
Chemical type: Peptide from protein
Sequence: DLDASREAKKQLEAEHQK
Position: 270-287
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: C1B p228-245
Chemical type: Peptide from protein
Sequence: DLDASREAKKQLEAEHQK
Position: 270-287
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: C1C2 p241-258
Chemical type: Peptide from protein
Sequence: AEHQKLEEQNKISEASRK
Position: 283-300
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: C1C2 p241-258
Chemical type: Peptide from protein
Sequence: AEHQKLEEQNKISEASRK
Position: 283-300
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: C2C3 p280-297
Chemical type: Peptide from protein
Sequence: KLEEQNKISEASRKGLRR
Position: 287-304
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: C2C3 p280-297
Chemical type: Peptide from protein
Sequence: KLEEQNKISEASRKGLRR
Position: 287-304
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: C3 p293-308
Chemical type: Peptide from protein
Sequence: KGLRRDLDASREAKKQ
Position: 265-280
Source molecule (GenBank): P02977.2
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: C3 p293-308
Chemical type: Peptide from protein
Sequence: KGLRRDLDASREAKKQ
Position: 265-280
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
MHC allele types: 169
Host:  4 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo