Reference: C Garrett Rappazzo; Ching-Lin Hsieh; Scott A Rush; Emma S Esterman; Teresa Delgado; James C Geoghegan; Anna Z Wec; Mrunal Sakharkar; Vicente Más; Jason S McLellan; Laura M Walker. "Potently neutralizing and protective anti-human metapneumovirus antibodies target diverse sites on the fusion glycoprotein." Immunity (2022).

Epitope: Epitope of MPE8 Fab on hMPV F
Chemical type: Region on multi-chain protein
Discontinuous residues: E: N395, R396, V397, G398, I399, N422, V424, Q426; F: L36, T41, G42, W43, R156, N233, M234, P235, T236, S237, L243, I275, G277, D280, T281, P282, Q312, A314, G315
Source molecule (GenBank): AEK26886.1
Assay category: BCell
Result: Positive
Quantitative measurement: 54.0

Epitope: Epitope of MPE8 Fab on hMPV F
Chemical type: Region on multi-chain protein
Discontinuous residues: E: N395, R396, V397, G398, I399, N422, V424, Q426; F: L36, T41, G42, W43, R156, N233, M234, P235, T236, S237, L243, I275, G277, D280, T281, P282, Q312, A314, G315
Source molecule (GenBank): AEK26886.1
Assay category: BCell
Result: Positive
Host:  21-72 years

Epitope: Epitope of MPE8 Fab on hMPV F
Chemical type: Region on multi-chain protein
Discontinuous residues: E: N395, R396, V397, G398, I399, N422, V424, Q426; F: L36, T41, G42, W43, R156, N233, M234, P235, T236, S237, L243, I275, G277, D280, T281, P282, Q312, A314, G315
Source molecule (GenBank): AEK26886.1
Assay category: BCell
Result: Positive

Epitope: Epitope of ADI-61026 Fab on hMPV F
Chemical type: Discontinuous protein residues
Discontinuous residues: D54, N57, L58, T59, K166, L173, T174, R175, I177, N178, K179, N180
Source molecule (GenBank): AEK26886.1
Assay category: BCell
Result: Positive
Host:  21-72 years

Epitope: Epitope of ADI-61026 Fab on hMPV F
Chemical type: Discontinuous protein residues
Discontinuous residues: D54, N57, L58, T59, K166, L173, T174, R175, I177, N178, K179, N180
Source molecule (GenBank): AEK26886.1
Assay category: BCell
Result: Positive
Host:  21-72 years

Epitope: Epitope of ADI-61026 Fab on hMPV F
Chemical type: Discontinuous protein residues
Discontinuous residues: D54, N57, L58, T59, K166, L173, T174, R175, I177, N178, K179, N180
Source molecule (GenBank): AEK26886.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.374
Host:  21-72 years

Epitope: Epitope of ADI-61026 Fab on hMPV F
Chemical type: Discontinuous protein residues
Discontinuous residues: D54, N57, L58, T59, K166, L173, T174, R175, I177, N178, K179, N180
Source molecule (GenBank): AEK26886.1
Assay category: BCell
Result: Positive
Host:  21-72 years

Epitope: Epitope of ADI-61026 Fab on hMPV F
Chemical type: Discontinuous protein residues
Discontinuous residues: D54, N57, L58, T59, K166, L173, T174, R175, I177, N178, K179, N180
Source molecule (GenBank): AEK26886.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.279
Host:  21-72 years

Epitope: Epitope of ADI-61026 Fab on hMPV F
Chemical type: Discontinuous protein residues
Discontinuous residues: D54, N57, L58, T59, K166, L173, T174, R175, I177, N178, K179, N180
Source molecule (GenBank): AEK26886.1
Assay category: BCell
Result: Positive
Host:  21-72 years

Epitope: Epitope of ADI-61026 Fab on hMPV F
Chemical type: Discontinuous protein residues
Discontinuous residues: D54, N57, L58, T59, K166, L173, T174, R175, I177, N178, K179, N180
Source molecule (GenBank): AEK26886.1
Assay category: BCell
Result: Positive
Host:  21-72 years

Epitope: Epitope of ADI-61026 Fab on hMPV F
Chemical type: Discontinuous protein residues
Discontinuous residues: D54, N57, L58, T59, K166, L173, T174, R175, I177, N178, K179, N180
Source molecule (GenBank): AEK26886.1
Assay category: BCell
Result: Positive
Host:  21-72 years

Epitope: Epitope of ADI-61026 Fab on hMPV F
Chemical type: Discontinuous protein residues
Discontinuous residues: D54, N57, L58, T59, K166, L173, T174, R175, I177, N178, K179, N180
Source molecule (GenBank): AEK26886.1
Assay category: BCell
Result: Positive
Host:  21-72 years