Reference: Metin Aksu; Priya Kumar; Thomas Güttler; Waltraud Taxer; Kathrin Gregor; Bianka Mußil; Oleh Rymarenko; Kim M Stegmann; Antje Dickmanns; Sabrina Gerber; Wencke Reineking; Claudia Schulz; Timo Henneck; Ahmed Mohamed; Gerhard Pohlmann; Mehmet Ramazanoglu; Kemal Mese; Uwe Groß; Tamar Ben-Yedidia; Oded Ovadia; Dalit Weinstein Fischer; Merav Kamensky; Amir Reichman; Wolfgang Baumgärtner; Maren von Köckritz-Blickwede; Matthias Dobbelstein; Dirk Görlich. "Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters." Antiviral research (2024).

Epitope: Epitope of nanobody Re30H02 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, R403, K417, G446, Y449, L452, L455, F456, T470, E484, F486, Y489, F490, L492, Q493, S494, Y495, Q498, N501, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of nanobody Re30H02 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, R403, K417, G446, Y449, L452, L455, F456, T470, E484, F486, Y489, F490, L492, Q493, S494, Y495, Q498, N501, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of nanobody Re30H02 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, R403, K417, G446, Y449, L452, L455, F456, T470, E484, F486, Y489, F490, L492, Q493, S494, Y495, Q498, N501, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.1
Host: F

Epitope: Epitope of nanobody Re30H02 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, R403, K417, G446, Y449, L452, L455, F456, T470, E484, F486, Y489, F490, L492, Q493, S494, Y495, Q498, N501, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.1
Host: F

Epitope: Epitope of nanobody Re30H02 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, R403, K417, G446, Y449, L452, L455, F456, T470, E484, F486, Y489, F490, L492, Q493, S494, Y495, Q498, N501, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.02
Host: F

Epitope: Epitope of nanobody Re30H02 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, R403, K417, G446, Y449, L452, L455, F456, T470, E484, F486, Y489, F490, L492, Q493, S494, Y495, Q498, N501, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of nanobody Re30H02 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, R403, K417, G446, Y449, L452, L455, F456, T470, E484, F486, Y489, F490, L492, Q493, S494, Y495, Q498, N501, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of nanobody Re30H02 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, R403, K417, G446, Y449, L452, L455, F456, T470, E484, F486, Y489, F490, L492, Q493, S494, Y495, Q498, N501, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.05
Host: F

Epitope: Epitope of nanobody Re30H02 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, R403, K417, G446, Y449, L452, L455, F456, T470, E484, F486, Y489, F490, L492, Q493, S494, Y495, Q498, N501, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.05
Host: F

Epitope: Epitope of nanobody Re30H02 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, R403, K417, G446, Y449, L452, L455, F456, T470, E484, F486, Y489, F490, L492, Q493, S494, Y495, Q498, N501, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Low
Host: F

Epitope: Epitope of nanobody Re32D03 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V442, S443, G444, Y446, L452, F453, G482, F483, N484, Y486, F487, L489, Q490, S491, Y492, G493, R495
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of nanobody Re32D03 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V442, S443, G444, Y446, L452, F453, G482, F483, N484, Y486, F487, L489, Q490, S491, Y492, G493, R495
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of nanobody Re32D03 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V442, S443, G444, Y446, L452, F453, G482, F483, N484, Y486, F487, L489, Q490, S491, Y492, G493, R495
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of nanobody Re32D03 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V442, S443, G444, Y446, L452, F453, G482, F483, N484, Y486, F487, L489, Q490, S491, Y492, G493, R495
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of nanobody Re32D03 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V442, S443, G444, Y446, L452, F453, G482, F483, N484, Y486, F487, L489, Q490, S491, Y492, G493, R495
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 20.0
Host: F

Epitope: Epitope of nanobody Re32D03 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V442, S443, G444, Y446, L452, F453, G482, F483, N484, Y486, F487, L489, Q490, S491, Y492, G493, R495
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.01
Host: F

Epitope: Epitope of nanobody Re32D03 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V442, S443, G444, Y446, L452, F453, G482, F483, N484, Y486, F487, L489, Q490, S491, Y492, G493, R495
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 50.0
Host: F

Epitope: Epitope of nanobody Re32D03 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V442, S443, G444, Y446, L452, F453, G482, F483, N484, Y486, F487, L489, Q490, S491, Y492, G493, R495
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.35
Host: F

Epitope: Epitope of nanobody Re32D03 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V442, S443, G444, Y446, L452, F453, G482, F483, N484, Y486, F487, L489, Q490, S491, Y492, G493, R495
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.01
Host: F

Epitope: Epitope of nanobody Re32D03 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V442, S443, G444, Y446, L452, F453, G482, F483, N484, Y486, F487, L489, Q490, S491, Y492, G493, R495
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.01
Host: F

Epitope: Epitope of nanobody Re32D03 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V442, S443, G444, Y446, L452, F453, G482, F483, N484, Y486, F487, L489, Q490, S491, Y492, G493, R495
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of nanobody Re32D03 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V442, S443, G444, Y446, L452, F453, G482, F483, N484, Y486, F487, L489, Q490, S491, Y492, G493, R495
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.5
Host: F

Epitope: Epitope of nanobody Re32D03 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V442, S443, G444, Y446, L452, F453, G482, F483, N484, Y486, F487, L489, Q490, S491, Y492, G493, R495
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00009804
Host: F

Epitope: Epitope of nanobody Re32D03 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V442, S443, G444, Y446, L452, F453, G482, F483, N484, Y486, F487, L489, Q490, S491, Y492, G493, R495
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of nanobody Re32D03 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V442, S443, G444, Y446, L452, F453, G482, F483, N484, Y486, F487, L489, Q490, S491, Y492, G493, R495
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.01
Host: F

Epitope: Epitope of nanobody Re32D03 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: V442, S443, G444, Y446, L452, F453, G482, F483, N484, Y486, F487, L489, Q490, S491, Y492, G493, R495
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive
Quantitative measurement: 486200.0
Host: F

Epitope: Epitope of nanobody Ma3B12 on SARS-CoV-2 Omicron BA.2.75 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: F372, T373, F374, K375, C376, Y377, V379, S380, P381, G401, V404, R405, Q411, V500, Y505
Source molecule (GenBank): UNL31452.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.5
Host: F

Epitope: Epitope of nanobody Ma6F06 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K417, G446, G447, Y449, L455, F456, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of nanobody Ma6F06 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K417, G446, G447, Y449, L455, F456, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of nanobody Ma6F06 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K417, G446, G447, Y449, L455, F456, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.05
Host: F

Epitope: Epitope of nanobody Ma6F06 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K417, G446, G447, Y449, L455, F456, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.03
Host: F

Epitope: Epitope of nanobody Ma6F06 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K417, G446, G447, Y449, L455, F456, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.01
Host: F

Epitope: Epitope of nanobody Ma6F06 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K417, G446, G447, Y449, L455, F456, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.06
Host: F

Epitope: Epitope of nanobody Ma6F06 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: K417, G446, G447, Y449, L455, F456, E484, G485, F486, N487, Y489, F490, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.7
Host: F

Epitope: Epitope of nanobody Re21H01 on SARS-CoV-2 WT RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, N370, S371, A372, F374, S375, T376, F377, K378, C379, Y380, P384, G404, D405, V407, R408, Q414, T500, N501, G502, V503, Y508
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.7
Host: F

Epitope: Epitope of nanobody Ma16B06 on SARS-CoV-2 Omicron BA.1 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y348, K441, V442, S443, G444, Y446, N447, L449, T467, F487, L489, R490, S491, R495
Source molecule (GenBank): UJU86738.1
Assay category: BCell
Result: Positive-Low
Host: F

Epitope: Epitope of nanobody Ma16B06 on SARS-CoV-2 Omicron BA.1 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y348, K441, V442, S443, G444, Y446, N447, L449, T467, F487, L489, R490, S491, R495
Source molecule (GenBank): UJU86738.1
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 20.0
Host: F

Epitope: Epitope of nanobody Ma16B06 on SARS-CoV-2 Omicron BA.1 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y348, K441, V442, S443, G444, Y446, N447, L449, T467, F487, L489, R490, S491, R495
Source molecule (GenBank): UJU86738.1
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 25.0
Host: F

Epitope: Epitope of nanobody Ma16B06 on SARS-CoV-2 Omicron BA.1 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y348, K441, V442, S443, G444, Y446, N447, L449, T467, F487, L489, R490, S491, R495
Source molecule (GenBank): UJU86738.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of nanobody Ma16B06 on SARS-CoV-2 Omicron BA.1 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y348, K441, V442, S443, G444, Y446, N447, L449, T467, F487, L489, R490, S491, R495
Source molecule (GenBank): UJU86738.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of nanobody Ma16B06 on SARS-CoV-2 Omicron BA.1 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y348, K441, V442, S443, G444, Y446, N447, L449, T467, F487, L489, R490, S491, R495
Source molecule (GenBank): UJU86738.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.01
Host: F

Epitope: Epitope of nanobody Ma16B06 on SARS-CoV-2 Omicron BA.1 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y348, K441, V442, S443, G444, Y446, N447, L449, T467, F487, L489, R490, S491, R495
Source molecule (GenBank): UJU86738.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.25
Host: F

Epitope: Epitope of nanobody Ma16B06 on SARS-CoV-2 Omicron BA.1 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y348, K441, V442, S443, G444, Y446, N447, L449, T467, F487, L489, R490, S491, R495
Source molecule (GenBank): UJU86738.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.06
Host: F

Epitope: Epitope of nanobody Ma16B06 on SARS-CoV-2 Omicron BA.1 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y348, K441, V442, S443, G444, Y446, N447, L449, T467, F487, L489, R490, S491, R495
Source molecule (GenBank): UJU86738.1
Assay category: BCell
Result: Positive-Intermediate
Quantitative measurement: 20.0
Host: F

Epitope: Epitope of nanobody Ma16B06 on SARS-CoV-2 Omicron BA.1 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y348, K441, V442, S443, G444, Y446, N447, L449, T467, F487, L489, R490, S491, R495
Source molecule (GenBank): UJU86738.1
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of nanobody Ma16B06 on SARS-CoV-2 Omicron BA.1 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y348, K441, V442, S443, G444, Y446, N447, L449, T467, F487, L489, R490, S491, R495
Source molecule (GenBank): UJU86738.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.04
Host: F

Epitope: Epitope of nanobody Ma16B06 on SARS-CoV-2 Omicron BA.1 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y348, K441, V442, S443, G444, Y446, N447, L449, T467, F487, L489, R490, S491, R495
Source molecule (GenBank): UJU86738.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.6
Host: F

Epitope: Epitope of nanobody Ma3F05 on SARS-CoV-2 Omicron BA.1 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y362, Y366, F372, T373, F374, K375, C376, Y377, V379, S380, P381, G401, V404, R405, Q411, Y505
Source molecule (GenBank): UJU86738.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.6
Host: F