Reference: David J Vance; Saiful Basir; Carol Lyn Piazza; Graham G Willsey; H M Emranul Haque; Jacque M Tremblay; Michael J Rudolph; Beatrice Muriuki; Lisa Cavacini; David D Weis; Charles B Shoemaker; Nicholas J Mantis. "Single-domain antibodies reveal unique borrelicidal epitopes on the Lyme disease vaccine antigen, outer surface protein A (OspA)." Infection and immunity (2024).

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive
Quantitative measurement: 154000.0

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000429

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.09

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.28

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.07

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive
Quantitative measurement: 184000.0

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000382

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive
Quantitative measurement: 371000.0

Epitope: Epitope of L8H8 family Nb
Chemical type: Discontinuous protein residues
Discontinuous residues: K129, G130, E131, V132, S133, E134, K135, I136, I137, T138, R139, A140, D141, G142, T143, R144, L145, T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000403

Epitope: Epitope of Nb L8D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb L8D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb L8D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb L8D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb L8D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive
Quantitative measurement: 10.4

Epitope: Epitope of Nb L8D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive
Quantitative measurement: 114000.0

Epitope: Epitope of Nb L8D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00118

Epitope: Epitope of Nb L8D3
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb L8G12
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb L8G12
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb L8G12
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb L8G12
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb L8G12
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb L8G12
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of Nb L8G12
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb L8G12
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb L8G12
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.94

Epitope: Epitope of Nb L8G12
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive
Quantitative measurement: 132000.0

Epitope: Epitope of Nb L8G12
Chemical type: Discontinuous protein residues
Discontinuous residues: T148, G149, I150, K151, S152, D153, G154, S155, G156, K157, K159, V161, L162, K163, G164, Y165, V166, L167, E168, G169, T170, L171, E174, K175, T177
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000124

Epitope: Epitope of LA-2
Chemical type: Discontinuous protein residues
Discontinuous residues: S206, S207, A208, A209, T210, K211, K212, T213, A214, A215, T226, V227, N228, S229, K230, K231, D249, S250, N251, G252, T253
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive

Epitope: Epitope of LA-2
Chemical type: Discontinuous protein residues
Discontinuous residues: S206, S207, A208, A209, T210, K211, K212, T213, A214, A215, T226, V227, N228, S229, K230, K231, D249, S250, N251, G252, T253
Source molecule (GenBank): WP_010890378.1
Assay category: BCell
Result: Positive