Reference: Inga Rimkute; Adam S Olia; Mehin Suleiman; Kamron D Woods; Tatsiana Bylund; Nicholas C Morano; Ena S Tully; Raffaello Verardi; Saran Bao; Margaret H Beddall; Natthawan Chaimongkol; Mitzi M Donaldson; Renguang Du; Caitlyn N M Dulan; Jason Gorman; Amy R Henry; Chaim A Schramm; Stanislav V Sosnovtsev; Tyler Stephens; John-Paul Todd; Yaroslav Tsybovsky; Daniel C Douek; Kim Y Green; Reda Rawi; Lawrence Shapiro; Tongqing Zhou; Peter D Kwong; Mario Roederer. "A broadly protective human antibody for GI genogroup noroviruses." Nature microbiology (2025).

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Quantitative measurement: 16.0
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4700.0
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Quantitative measurement: 79100.0
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Quantitative measurement: 38.8
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Quantitative measurement: 40.0
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Quantitative measurement: 20.0
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Host: M 59 years

Epitope: Epitope of 16E10 Fab on norovirus GI.1 P domain
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L236, P237, S240, P464, D465, L470, Q493, Q494, L495, P496, I497, N498; B: G274, R275, L276, G278, T280, R291, E303, D305, G306, T307, P308, F309, H310, F312, E313, I318, E401, A446, Q449, P451
Source molecule (GenBank): AFJ38516.1
Assay category: BCell
Result: Positive
Host: M 59 years