Reference: K C Faé; S E Oshiro; A Toubert; D Charron; J Kalil; L Guilherme. "How an autoimmune reaction triggered by molecular mimicry between streptococcal M protein and cardiac tissue proteins leads to heart lesions in rheumatic heart disease." Journal of autoimmunity (2005).

Epitope: M5 (81-96)
Chemical type: Peptide from protein
Sequence: DKLKQQRDTLSTQKET
Position: 112-127
Source molecule (GenBank): AAN04084.1
Assay category: TCell
Result: Positive
Host: M 6-10 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: M5 (81-96)
Chemical type: Peptide from protein
Sequence: DKLKQQRDTLSTQKET
Position: 112-127
Source molecule (GenBank): AAN04084.1
Assay category: TCell
Result: Positive
Host: M 6 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: M5 (81-96)
Chemical type: Peptide from protein
Sequence: DKLKQQRDTLSTQKET
Position: 112-127
Source molecule (GenBank): AAN04084.1
Assay category: TCell
Result: Positive
Host: M 10 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: M5 (81-96)
Chemical type: Peptide from protein
Sequence: DKLKQQRDTLSTQKET
Position: 112-127
Source molecule (GenBank): AAN04084.1
Assay category: TCell
Result: Positive
Host: M 6 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: M5 (81-96)
Chemical type: Peptide from protein
Sequence: DKLKQQRDTLSTQKET
Position: 112-127
Source molecule (GenBank): AAN04084.1
Assay category: TCell
Result: Positive
Host: M 6-10 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: M5 (81-96)
Chemical type: Peptide from protein
Sequence: DKLKQQRDTLSTQKET
Position: 112-127
Source molecule (GenBank): AAN04084.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 670.0

Epitope: M5 (163-177)
Chemical type: Peptide from protein
Sequence: ETIGLKKILDETVK
Assay category: TCell
Result: Positive
MHC allele types: 336 350 344 347 345 330 353
Host: M 6-10 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: LMM25 (1607-1624)
Chemical type: Peptide from protein
Sequence: RSRNEALRVKKKMEGDLN
Position: 1606-1623
Source molecule (GenBank): P12883.5
Assay category: TCell
Result: Positive
MHC allele types: 336 350 344 347
Host: M 6 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: LMM25 (1607-1624)
Chemical type: Peptide from protein
Sequence: RSRNEALRVKKKMEGDLN
Position: 1606-1623
Source molecule (GenBank): P12883.5
Assay category: TCell
Result: Positive
MHC allele types: 336 350 344 347
Host: M 6 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: LMM25 (1607-1624)
Chemical type: Peptide from protein
Sequence: RSRNEALRVKKKMEGDLN
Position: 1606-1623
Source molecule (GenBank): P12883.5
Assay category: TCell
Result: Positive
MHC allele types: 336 350 344 347
Host: M 6 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: LMM25 (1607-1624)
Chemical type: Peptide from protein
Sequence: RSRNEALRVKKKMEGDLN
Position: 1606-1623
Source molecule (GenBank): P12883.5
Assay category: TCell
Result: Positive
MHC allele types: 336 350 344 347
Host: M 6 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: M5 (1-20)
Chemical type: Peptide from protein
Sequence: TVTRGTISDPQRAKEALDKY
Assay category: TCell
Result: Positive
MHC allele types: 336 350 344 347
Host: M 6 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: M5 (1-20)
Chemical type: Peptide from protein
Sequence: TVTRGTISDPQRAKEALDKY
Assay category: TCell
Result: Positive
MHC allele types: 336 350 344 347
Host: M 6 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: LMM48 (1907-1924)
Chemical type: Peptide from protein
Sequence: AEERADIAESQVNKLRAK
Position: 1906-1923
Source molecule (GenBank): P12883.5
Assay category: TCell
Result: Positive
MHC allele types: 336 350 344 347
Host: M 6 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: LMM48 (1907-1924)
Chemical type: Peptide from protein
Sequence: AEERADIAESQVNKLRAK
Position: 1906-1923
Source molecule (GenBank): P12883.5
Assay category: TCell
Result: Positive
MHC allele types: 336 350 344 347
Host: M 6 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: LMM48 (1907-1924)
Chemical type: Peptide from protein
Sequence: AEERADIAESQVNKLRAK
Position: 1906-1923
Source molecule (GenBank): P12883.5
Assay category: TCell
Result: Positive
MHC allele types: 336 350 344 347
Host: M 6 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: LMM48 (1907-1924)
Chemical type: Peptide from protein
Sequence: AEERADIAESQVNKLRAK
Position: 1906-1923
Source molecule (GenBank): P12883.5
Assay category: TCell
Result: Positive
MHC allele types: 336 350 344 347
Host: M 6 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: M5 (11-25)
Chemical type: Peptide from protein
Sequence: QRAKEALDKYELENH
Position: 26-40
Source molecule (GenBank): CAI77246.1
Assay category: TCell
Result: Positive
MHC allele types: 353 330 345 347
Host: M 10 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone

Epitope: M5 (183-197)
Chemical type: Peptide from protein
Sequence: EQKSKQNIGALKQEL
Position: 207-221
Source molecule (GenBank): AAQ94545.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 89.0