Reference: Jinpan Hu; Zijing Jia; Meng Wang; Lingling Nie; Wangjun Fu; Qingfeng Zhang; Haiyang Qin; Jianhui Nie; Xiaoyu Xu; Lingjie Xu; Fengze Wang; Yingping Chen; Bo Xing; Tao Li; Danfeng Li; Shaowei Li; Ningshao Xia; Xiangxi Wang; Weijin Huang. "Establishing a universal IVRP method for quadrivalent HPV vaccines to replace in vivo potency tests." NPJ vaccines (2025).

Epitope: Epitope of Fab F5-77 on HPV6 L1 pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: J: D124, D125, N128, G130, S131, G132, G133, N134, P135, G136, Q137, N278, R279, S281, V282, G283; K: Y123, D124, G130, S131, G132, G133, N134, N139, G277, N278
Source molecule (GenBank): CAS89487.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-77 on HPV6 L1 pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: J: D124, D125, N128, G130, S131, G132, G133, N134, P135, G136, Q137, N278, R279, S281, V282, G283; K: Y123, D124, G130, S131, G132, G133, N134, N139, G277, N278
Source molecule (GenBank): CAS89487.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-77 on HPV6 L1 pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: J: D124, D125, N128, G130, S131, G132, G133, N134, P135, G136, Q137, N278, R279, S281, V282, G283; K: Y123, D124, G130, S131, G132, G133, N134, N139, G277, N278
Source molecule (GenBank): CAS89487.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-77 on HPV6 L1 pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: J: D124, D125, N128, G130, S131, G132, G133, N134, P135, G136, Q137, N278, R279, S281, V282, G283; K: Y123, D124, G130, S131, G132, G133, N134, N139, G277, N278
Source molecule (GenBank): CAS89487.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-77 on HPV6 L1 pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: J: D124, D125, N128, G130, S131, G132, G133, N134, P135, G136, Q137, N278, R279, S281, V282, G283; K: Y123, D124, G130, S131, G132, G133, N134, N139, G277, N278
Source molecule (GenBank): CAS89487.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-187 on HPV11 L1 pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: D: G131, Y132, G134, N135, N279; F: D124, S129, G130, G134, N135, N353, S354
Source molecule (GenBank): ACL12350.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-187 on HPV11 L1 pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: D: G131, Y132, G134, N135, N279; F: D124, S129, G130, G134, N135, N353, S354
Source molecule (GenBank): ACL12350.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-187 on HPV11 L1 pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: D: G131, Y132, G134, N135, N279; F: D124, S129, G130, G134, N135, N353, S354
Source molecule (GenBank): ACL12350.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-187 on HPV11 L1 pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: D: G131, Y132, G134, N135, N279; F: D124, S129, G130, G134, N135, N353, S354
Source molecule (GenBank): ACL12350.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-187 on HPV11 L1 pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: D: G131, Y132, G134, N135, N279; F: D124, S129, G130, G134, N135, N353, S354
Source molecule (GenBank): ACL12350.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-196 on HPV16 L1 pentamer
Chemical type: Discontinuous protein residues
Discontinuous residues: N164, A165, G166, G291, V293, N296, K304, S306, G307, S308, A310, N311, L312
Source molecule (GenBank): P03101.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-196 on HPV16 L1 pentamer
Chemical type: Discontinuous protein residues
Discontinuous residues: N164, A165, G166, G291, V293, N296, K304, S306, G307, S308, A310, N311, L312
Source molecule (GenBank): P03101.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-196 on HPV16 L1 pentamer
Chemical type: Discontinuous protein residues
Discontinuous residues: N164, A165, G166, G291, V293, N296, K304, S306, G307, S308, A310, N311, L312
Source molecule (GenBank): P03101.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-196 on HPV16 L1 pentamer
Chemical type: Discontinuous protein residues
Discontinuous residues: N164, A165, G166, G291, V293, N296, K304, S306, G307, S308, A310, N311, L312
Source molecule (GenBank): P03101.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-196 on HPV16 L1 pentamer
Chemical type: Discontinuous protein residues
Discontinuous residues: N164, A165, G166, G291, V293, N296, K304, S306, G307, S308, A310, N311, L312
Source molecule (GenBank): P03101.2
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Fab F5-203 on HPV18 L1 pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: D127, S132, A134, T136, S137, N138, V139, S140, E141, T280, M282, R283, G287; B: P121, F122, L126, A134, E141, V143, R144, D145, N146
Source molecule (GenBank): ATL15246.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-203 on HPV18 L1 pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: D127, S132, A134, T136, S137, N138, V139, S140, E141, T280, M282, R283, G287; B: P121, F122, L126, A134, E141, V143, R144, D145, N146
Source molecule (GenBank): ATL15246.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-203 on HPV18 L1 pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: D127, S132, A134, T136, S137, N138, V139, S140, E141, T280, M282, R283, G287; B: P121, F122, L126, A134, E141, V143, R144, D145, N146
Source molecule (GenBank): ATL15246.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-203 on HPV18 L1 pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: D127, S132, A134, T136, S137, N138, V139, S140, E141, T280, M282, R283, G287; B: P121, F122, L126, A134, E141, V143, R144, D145, N146
Source molecule (GenBank): ATL15246.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab F5-203 on HPV18 L1 pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: D127, S132, A134, T136, S137, N138, V139, S140, E141, T280, M282, R283, G287; B: P121, F122, L126, A134, E141, V143, R144, D145, N146
Source molecule (GenBank): ATL15246.1
Assay category: BCell
Result: Positive