Reference: Audrey Le Floc'h; Kirsten Nagashima; Dylan Birchard; George Scott; Li-Hong Ben; Dharani Ajithdoss; Kaitlyn Gayvert; Annabel Romero Hernandez; Olivier Herbin; Amanda Tay; Pamela Farrales; Chandrashekhar K Korgaonkar; Hao Pan; Sweta Shah; Vishal Kamat; Ishita Chatterjee; Jon Popke; Adelekan Oyejide; Wei Keat Lim; Jee H Kim; Tammy Huang; Matthew Franklin; William Olson; Thomas Norton; Lorah Perlee; George D Yancopoulos; Andrew J Murphy; Matthew A Sleeman; Jamie M Orengo. "Blocking common γ chain cytokine signaling ameliorates T cell-mediated pathogenesis in disease models." Science translational medicine (2023).

Epitope: Epitope of REGN7257 on IL-2RG chain
Chemical type: Discontinuous protein residues
Discontinuous residues: W90, K92, N93, S94, D95, D97, V99, T127, R140, Q141, T143, Q144, M145
Source molecule (GenBank): P31785.1
Assay category: BCell
Result: Negative

Epitope: Epitope of REGN7257 on IL-2RG chain
Chemical type: Discontinuous protein residues
Discontinuous residues: W90, K92, N93, S94, D95, D97, V99, T127, R140, Q141, T143, Q144, M145
Source molecule (GenBank): P31785.1
Assay category: BCell
Result: Positive

Epitope: Epitope of REGN7257 on IL-2RG chain
Chemical type: Discontinuous protein residues
Discontinuous residues: W90, K92, N93, S94, D95, D97, V99, T127, R140, Q141, T143, Q144, M145
Source molecule (GenBank): P31785.1
Assay category: BCell
Result: Positive

Epitope: Epitope of REGN7257 on IL-2RG chain
Chemical type: Discontinuous protein residues
Discontinuous residues: W90, K92, N93, S94, D95, D97, V99, T127, R140, Q141, T143, Q144, M145
Source molecule (GenBank): P31785.1
Assay category: BCell
Result: Positive

Epitope: Epitope of REGN7257 on IL-2RG chain
Chemical type: Discontinuous protein residues
Discontinuous residues: W90, K92, N93, S94, D95, D97, V99, T127, R140, Q141, T143, Q144, M145
Source molecule (GenBank): P31785.1
Assay category: BCell
Result: Positive

Epitope: Epitope of REGN7257 on IL-2RG chain
Chemical type: Discontinuous protein residues
Discontinuous residues: W90, K92, N93, S94, D95, D97, V99, T127, R140, Q141, T143, Q144, M145
Source molecule (GenBank): P31785.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.318

Epitope: Epitope of REGN7257 on IL-2RG chain
Chemical type: Discontinuous protein residues
Discontinuous residues: W90, K92, N93, S94, D95, D97, V99, T127, R140, Q141, T143, Q144, M145
Source molecule (GenBank): P31785.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.386

Epitope: Epitope of REGN7257 on IL-2RG chain
Chemical type: Discontinuous protein residues
Discontinuous residues: W90, K92, N93, S94, D95, D97, V99, T127, R140, Q141, T143, Q144, M145
Source molecule (GenBank): P31785.1
Assay category: BCell
Result: Positive
Quantitative measurement: 260000.0

Epitope: Epitope of REGN7257 on IL-2RG chain
Chemical type: Discontinuous protein residues
Discontinuous residues: W90, K92, N93, S94, D95, D97, V99, T127, R140, Q141, T143, Q144, M145
Source molecule (GenBank): P31785.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00010

Epitope: Epitope of REGN7257 on IL-2RG chain
Chemical type: Discontinuous protein residues
Discontinuous residues: W90, K92, N93, S94, D95, D97, V99, T127, R140, Q141, T143, Q144, M145
Source molecule (GenBank): P31785.1
Assay category: BCell
Result: Positive

Epitope: Epitope of REGN7257 on IL-2RG chain
Chemical type: Discontinuous protein residues
Discontinuous residues: W90, K92, N93, S94, D95, D97, V99, T127, R140, Q141, T143, Q144, M145
Source molecule (GenBank): P31785.1
Assay category: BCell
Result: Positive
Quantitative measurement: 332000.0

Epitope: Epitope of REGN7257 on IL-2RG chain
Chemical type: Discontinuous protein residues
Discontinuous residues: W90, K92, N93, S94, D95, D97, V99, T127, R140, Q141, T143, Q144, M145
Source molecule (GenBank): P31785.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000105

Epitope: Epitope of REGN7257 on IL-2RG chain
Chemical type: Discontinuous protein residues
Discontinuous residues: W90, K92, N93, S94, D95, D97, V99, T127, R140, Q141, T143, Q144, M145
Source molecule (GenBank): P31785.1
Assay category: BCell
Result: Positive

Epitope: Epitope of REGN9432 on IL-2RG chain
Chemical type: Discontinuous protein residues
Discontinuous residues: R190, T191, D192, W193, H195, W197, R218, Y219, T220, R222, H242, P243, H245
Source molecule (GenBank): P31785.1
Assay category: BCell
Result: Positive