Reference: P Kjellén; U Brunsberg; J Broddefalk; B Hansen; M Vestberg; I Ivarsson; A Engström; A Svejgaard; J Kihlberg; L Fugger; R Holmdahl. "The structural basis of MHC control of collagen-induced arthritis; binding of the immunodominant type II collagen 256-270 glycopeptide to H-2Aq and H-2Ap molecules." European journal of immunology (1998).

Epitope: CII 256-270
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPK
Position: 388-402
Source molecule (GenBank): P05539.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: CII 256-270
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPK
Position: 388-402
Source molecule (GenBank): P05539.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: CII 256-270
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPK
Position: 388-402
Source molecule (GenBank): P05539.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: CII 256-270
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPK
Position: 388-402
Source molecule (GenBank): P05539.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: CII 256-270
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPK
Position: 388-402
Source molecule (GenBank): P05539.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 5700.0

Epitope: CII 256-270
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPK
Position: 388-402
Source molecule (GenBank): P05539.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10000.0

Epitope: CII 256-270 G256A
Chemical type: Peptide, no natural source
Sequence: AEPGIAGFKGEQGPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 4000.0

Epitope: CII 256-270 G256A
Chemical type: Peptide, no natural source
Sequence: AEPGIAGFKGEQGPK
Assay category: MhcBinding
Result: Positive

Epitope: CII 256-270 E257A
Chemical type: Peptide, no natural source
Sequence: GAPGIAGFKGEQGPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 3000.0

Epitope: CII 256-270 E257A
Chemical type: Peptide, no natural source
Sequence: GAPGIAGFKGEQGPK
Assay category: MhcBinding
Result: Positive

Epitope: CII 256-270 P258A
Chemical type: Peptide, no natural source
Sequence: GEAGIAGFKGEQGPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 4000.0

Epitope: CII 256-270 P258A
Chemical type: Peptide, no natural source
Sequence: GEAGIAGFKGEQGPK
Assay category: MhcBinding
Result: Positive

Epitope: CII 256-270 I260A
Chemical type: Peptide, no natural source
Sequence: GEPGAAGFKGEQGPK
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: CII 256-270 I260A
Chemical type: Peptide, no natural source
Sequence: GEPGAAGFKGEQGPK
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 70000.0

Epitope: CII 256-270 G262A
Chemical type: Peptide, no natural source
Sequence: GEPGIAAFKGEQGPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 4000.0

Epitope: CII 256-270 G262A
Chemical type: Peptide, no natural source
Sequence: GEPGIAAFKGEQGPK
Assay category: MhcBinding
Result: Positive

Epitope: CII 256-270 F263A
Chemical type: Peptide, no natural source
Sequence: GEPGIAGAKGEQGPK
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: CII 256-270 F263A
Chemical type: Peptide, no natural source
Sequence: GEPGIAGAKGEQGPK
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 80000.0

Epitope: CII 256-270 K264A
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFAGEQGPK
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 30000.0

Epitope: CII 256-270 K264A
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFAGEQGPK
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: CII 256-270 G265A
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKAEQGPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2000.0

Epitope: CII 256-270 G265A
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKAEQGPK
Assay category: MhcBinding
Result: Positive

Epitope: CII 256-270 E266A
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGAQGPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1200.0

Epitope: CII 256-270 E266A
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGAQGPK
Assay category: MhcBinding
Result: Positive

Epitope: CII 256-270 Q267A
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGEAGPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2500.0

Epitope: CII 256-270 Q267A
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGEAGPK
Assay category: MhcBinding
Result: Positive

Epitope: CII 256-270 G268A
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGEQAPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 3000.0

Epitope: CII 256-270 G268A
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGEQAPK
Assay category: MhcBinding
Result: Positive

Epitope: CII 256-270 P269A
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGEQGAK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2500.0

Epitope: CII 256-270 P269A
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGEQGAK
Assay category: MhcBinding
Result: Positive

Epitope: CII 256-270 K270A
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGEQGPA
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2000.0

Epitope: CII 256-270 K270A
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGEQGPA
Assay category: MhcBinding
Result: Positive

Epitope: CII 256-270 P258Hyl
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFKGEQGPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 3700.0

Epitope: CII 256-270 K264->Gal-HnV
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFVGEQGPK
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: CII 256-270 K264->Gal-HnV
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFVGEQGPK
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: CII 256-270 K264->Gal-HnV
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFVGEQGPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 15000.0

Epitope: CII 256-270 K264->Glc-Gal-HnV
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFVGEQGPK
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: CII 256-270 K264->Glc-Gal-HnV
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFVGEQGPK
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: CII 256-270 K264->Glc-Gal-HnV
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFVGEQGPK
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: CII 256-270 K264->Glc-Gal-HnV
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFVGEQGPK
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: CII 256-270 K264->Glc-Gal-HnV
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFVGEQGPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 20000.0

Epitope: CII 256-270 G259A
Chemical type: Peptide, no natural source
Sequence: GEPAIAGFKGEQGPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 4000.0

Epitope: CII 256-270 G259A
Chemical type: Peptide, no natural source
Sequence: GEPAIAGFKGEQGPK
Assay category: MhcBinding
Result: Positive

Epitope: CII 256-270 G259A, K264->Gal-HnV
Chemical type: Peptide, no natural source
Sequence: GEPAIAGFVGEQGPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10000.0

Epitope: CII 256-270 G262A, K264->Gal-HnV
Chemical type: Peptide, no natural source
Sequence: GEPGIAAFVGEQGPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10000.0

Epitope: CII 256-270 G265A, K264->Gal-HnV
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFVAEQGPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10000.0

Epitope: CII 256-270 E266A, K264->Gal-HnV
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFVGAQGPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 3000.0

Epitope: CII 256-270 Q267A, K264->Gal-HnV
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFVGEAGPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 17000.0

Epitope: CII 256-270 G268A, K264->Gal-HnV
Chemical type: Peptide, no natural source
Sequence: GEPGIAGFVGEQAPK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10000.0

Epitope: CII 256-270 K264->Glc-Gal-HnV
Chemical type: Peptide from protein
Sequence: GEPGIAGFKGEQGPK
Position: 388-402
Source molecule (GenBank): P05539.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 15000.0

Epitope: CII 256-270 I260A, K264->Gal-HnV
Chemical type: Peptide, no natural source
Sequence: GEPGAAGFVGEQGPK
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0

Epitope: CII 256-270 F263A, K264->Gal-HnV
Chemical type: Peptide, no natural source
Sequence: GEPGIAGAVGEQGPK
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 250000.0