Reference: Guihai Liu; Elie Antoun; Anastasia Fries; Xuan Yao; Zixi Yin; Danning Dong; Wenbo Wang; Peter A C Wing; Wanwisa Dejnirattisa; Piyada Supasa; Chang Liu; Timothy Rostron; Craig Waugh; Kevin Clark; Paul Sopp; Jeremy W Fry; Iolanda Vendrell; Jane A McKeating; Juthathip Mongkolsapaya; Gavin R Screaton; Benedikt M Kessler; Roman Fisher; Graham Ogg; Alexander J Mentzer; Julian C Knight; Yanchun Peng; Tao Dong. "Long-persisting SARS-CoV-2 spike-specific CD4<sup>+</sup> T cells associated with mild disease and increased cytotoxicity post COVID-19." Nature communications (2025).

Epitope: S 166-180
Chemical type: Peptide from protein
Sequence: CTFEYVSQPFLMDLE
Position: 166-180
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 166-180
Chemical type: Peptide from protein
Sequence: CTFEYVSQPFLMDLE
Position: 166-180
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S 166-180
Chemical type: Peptide from protein
Sequence: CTFEYVSQPFLMDLE
Position: 166-180
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 166-180
Chemical type: Peptide from protein
Sequence: CTFEYVSQPFLMDLE
Position: 166-180
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 166-180
Chemical type: Peptide from protein
Sequence: CTFEYVSQPFLMDLE
Position: 166-180
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S 166-180
Chemical type: Peptide from protein
Sequence: CTFEYVSQPFLMDLE
Position: 166-180
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 166-180
Chemical type: Peptide from protein
Sequence: CTFEYVSQPFLMDLE
Position: 166-180
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 751-765
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNR
Position: 751-765
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 751-765
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNR
Position: 751-765
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 751-765
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNR
Position: 751-765
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 751-765
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNR
Position: 751-765
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 751-765
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNR
Position: 751-765
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S 751-765
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNR
Position: 751-765
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S 751-765
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNR
Position: 751-765
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 751-765
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNR
Position: 751-765
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 751-765
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNR
Position: 751-765
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 751-765
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNR
Position: 751-765
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 751-765
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNR
Position: 751-765
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 751-765
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNR
Position: 751-765
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 751-765
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNR
Position: 751-765
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 751-765
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNR
Position: 751-765
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 866-880
Chemical type: Peptide from protein
Sequence: TDEMIAQYTSALLAG
Position: 866-880
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 866-880
Chemical type: Peptide from protein
Sequence: TDEMIAQYTSALLAG
Position: 866-880
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 866-880
Chemical type: Peptide from protein
Sequence: TDEMIAQYTSALLAG
Position: 866-880
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 866-880
Chemical type: Peptide from protein
Sequence: TDEMIAQYTSALLAG
Position: 866-880
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 866-880
Chemical type: Peptide from protein
Sequence: TDEMIAQYTSALLAG
Position: 866-880
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: S 866-880
Chemical type: Peptide from protein
Sequence: TDEMIAQYTSALLAG
Position: 866-880
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S 866-880
Chemical type: Peptide from protein
Sequence: TDEMIAQYTSALLAG
Position: 866-880
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo