Reference: Roberto Gozalbo-Rovira; Jesús Rodríguez-Díaz; Juan Saus; Javier Cervera. "Precise mapping of the Goodpasture epitope(s) using phage display, site-directed mutagenesis, and surface plasmon resonance." Kidney international (2013).

Epitope: Goodpasture disease autoimmune epitope in α3(IV)NC1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T1455, A1456, I1457, S1459, E1462, T1464, V1465, P1466, Y1468, S1469, Q1495, T1537, T1565, P1569, H1572, K1579, A1634
Source molecule (GenBank): CAC36101.1
Assay category: BCell
Result: Positive
Host: M 58 years

Epitope: Goodpasture disease autoimmune epitope in α3(IV)NC1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T1455, A1456, I1457, S1459, E1462, T1464, V1465, P1466, Y1468, S1469, Q1495, T1537, T1565, P1569, H1572, K1579, A1634
Source molecule (GenBank): CAC36101.1
Assay category: BCell
Result: Positive
Host: M 58 years

Epitope: Goodpasture disease autoimmune epitope in α3(IV)NC1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T1455, A1456, I1457, S1459, E1462, T1464, V1465, P1466, Y1468, S1469, Q1495, T1537, T1565, P1569, H1572, K1579, A1634
Source molecule (GenBank): CAC36101.1
Assay category: BCell
Result: Positive
Host: M 58 years

Epitope: Goodpasture disease autoimmune epitope in α3(IV)NC1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T1455, A1456, I1457, S1459, E1462, T1464, V1465, P1466, Y1468, S1469, Q1495, T1537, T1565, P1569, H1572, K1579, A1634
Source molecule (GenBank): CAC36101.1
Assay category: BCell
Result: Positive
Host: M 58 years

Epitope: Goodpasture disease autoimmune epitope in α3(IV)NC1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T1455, A1456, I1457, S1459, E1462, T1464, V1465, P1466, Y1468, S1469, Q1495, T1537, T1565, P1569, H1572, K1579, A1634
Source molecule (GenBank): CAC36101.1
Assay category: BCell
Result: Positive
Host: M 58 years

Epitope: Goodpasture disease autoimmune epitope in α3(IV)NC1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T1455, A1456, I1457, S1459, E1462, T1464, V1465, P1466, Y1468, S1469, Q1495, T1537, T1565, P1569, H1572, K1579, A1634
Source molecule (GenBank): CAC36101.1
Assay category: BCell
Result: Positive
Host: M 58 years

Epitope: Goodpasture disease autoimmune epitope in α3(IV)NC1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T1455, A1456, I1457, S1459, E1462, T1464, V1465, P1466, Y1468, S1469, Q1495, T1537, T1565, P1569, H1572, K1579, A1634
Source molecule (GenBank): CAC36101.1
Assay category: BCell
Result: Positive
Host: M 58 years

Epitope: Goodpasture disease autoimmune epitope in α3(IV)NC1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T1455, A1456, I1457, S1459, E1462, T1464, V1465, P1466, Y1468, S1469, Q1495, T1537, T1565, P1569, H1572, K1579, A1634
Source molecule (GenBank): CAC36101.1
Assay category: BCell
Result: Positive
Host: M 58 years

Epitope: Goodpasture disease autoimmune epitope in α3(IV)NC1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T1455, A1456, I1457, S1459, E1462, T1464, V1465, P1466, Y1468, S1469, Q1495, T1537, T1565, P1569, H1572, K1579, A1634
Source molecule (GenBank): CAC36101.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.5
Host: M 58 years

Epitope: Goodpasture disease autoimmune epitope in α3(IV)NC1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T1455, A1456, I1457, S1459, E1462, T1464, V1465, P1466, Y1468, S1469, Q1495, T1537, T1565, P1569, H1572, K1579, A1634
Source molecule (GenBank): CAC36101.1
Assay category: BCell
Result: Positive
Host: M 58 years

Epitope: Goodpasture disease autoimmune epitope in α3(IV)NC1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T1455, A1456, I1457, S1459, E1462, T1464, V1465, P1466, Y1468, S1469, Q1495, T1537, T1565, P1569, H1572, K1579, A1634
Source molecule (GenBank): CAC36101.1
Assay category: BCell
Result: Positive
Host: M 58 years

Epitope: Goodpasture disease autoimmune epitope in α3(IV)NC1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T1455, A1456, I1457, S1459, E1462, T1464, V1465, P1466, Y1468, S1469, Q1495, T1537, T1565, P1569, H1572, K1579, A1634
Source molecule (GenBank): CAC36101.1
Assay category: BCell
Result: Positive
Host: M 58 years

Epitope: Goodpasture disease autoimmune epitope in α3(IV)NC1 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: T1455, A1456, I1457, S1459, E1462, T1464, V1465, P1466, Y1468, S1469, Q1495, T1537, T1565, P1569, H1572, K1579, A1634
Source molecule (GenBank): CAC36101.1
Assay category: BCell
Result: Positive
Host: M 58 years

Epitope: Epitope of mAb M31A
Chemical type: Peptide from protein
Sequence: KGKRGDSGSPATWTTRGFVFT
Position: 1429-1449
Source molecule (GenBank): CAC36101.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb3
Chemical type: Discontinuous protein residues
Discontinuous residues: S1459, P1466, S1469
Source molecule (GenBank): CAC36101.1
Assay category: BCell
Result: Positive