Reference: Kuang-Ting Ko; Frank Lennartz; David Mekhaiel; Bora Guloglu; Arianna Marini; Danielle J Deuker; Carole A Long; Matthijs M Jore; Kazutoyo Miura; Sumi Biswas; Matthew K Higgins. "Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies." Nature communications (2022).

Epitope: Epitope of 85RF45.1 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: D321, D347, I349, P350, D351, Q355, S367, I369, Y371, K392, K394, K413, K414, D415, K416
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1380000.0

Epitope: Epitope of 85RF45.1 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: D321, D347, I349, P350, D351, Q355, S367, I369, Y371, K392, K394, K413, K414, D415, K416
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.34

Epitope: Epitope of 85RF45.1 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: D321, D347, I349, P350, D351, Q355, S367, I369, Y371, K392, K394, K413, K414, D415, K416
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.001862

Epitope: Epitope of 85RF45.1 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: D321, D347, I349, P350, D351, Q355, S367, I369, Y371, K392, K394, K413, K414, D415, K416
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 85RF45.1 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: D321, D347, I349, P350, D351, Q355, S367, I369, Y371, K392, K394, K413, K414, D415, K416
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.72

Epitope: Epitope of 32F3 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: S322, A323, H324, D347, I349, Y357, Q358, P359, E360, S361, E362, E363, L364, E365, P366, S367, N368, I369, T409, I411, K413, D415, K416, Y420
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.69

Epitope: Epitope of 32F3 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: S322, A323, H324, D347, I349, Y357, Q358, P359, E360, S361, E362, E363, L364, E365, P366, S367, N368, I369, T409, I411, K413, D415, K416, Y420
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.9

Epitope: Epitope of 32F3 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: S322, A323, H324, D347, I349, Y357, Q358, P359, E360, S361, E362, E363, L364, E365, P366, S367, N368, I369, T409, I411, K413, D415, K416, Y420
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2940000.0

Epitope: Epitope of 32F3 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: S322, A323, H324, D347, I349, Y357, Q358, P359, E360, S361, E362, E363, L364, E365, P366, S367, N368, I369, T409, I411, K413, D415, K416, Y420
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.13

Epitope: Epitope of 32F3 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: S322, A323, H324, D347, I349, Y357, Q358, P359, E360, S361, E362, E363, L364, E365, P366, S367, N368, I369, T409, I411, K413, D415, K416, Y420
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000121

Epitope: Epitope of 32F3 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: S322, A323, H324, D347, I349, Y357, Q358, P359, E360, S361, E362, E363, L364, E365, P366, S367, N368, I369, T409, I411, K413, D415, K416, Y420
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.1

Epitope: Epitope of 10D8 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: Y203, E205, S206, N207, F208, V209, S210, E214, V215, E216, D268, V285, L286, K287, P288, K289, Y290
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.69
Host: F 6-8 weeks

Epitope: Epitope of 10D8 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: Y203, E205, S206, N207, F208, V209, S210, E214, V215, E216, D268, V285, L286, K287, P288, K289, Y290
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.2
Host: F 6-8 weeks

Epitope: Epitope of 10D8 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: Y203, E205, S206, N207, F208, V209, S210, E214, V215, E216, D268, V285, L286, K287, P288, K289, Y290
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.72
Host: F 6-8 weeks

Epitope: Epitope of 10D8 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: Y203, E205, S206, N207, F208, V209, S210, E214, V215, E216, D268, V285, L286, K287, P288, K289, Y290
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.002702
Host: F 6-8 weeks

Epitope: Epitope of 10D8 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: Y203, E205, S206, N207, F208, V209, S210, E214, V215, E216, D268, V285, L286, K287, P288, K289, Y290
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: Epitope of 10D8 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: Y203, E205, S206, N207, F208, V209, S210, E214, V215, E216, D268, V285, L286, K287, P288, K289, Y290
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Quantitative measurement: 75500.0
Host: F 6-8 weeks

Epitope: Epitope of 10D8 Fab on P. falciparum gametocyte surface protein P48/45
Chemical type: Discontinuous protein residues
Discontinuous residues: Y203, E205, S206, N207, F208, V209, S210, E214, V215, E216, D268, V285, L286, K287, P288, K289, Y290
Source molecule (GenBank): Q8I6T1.1
Assay category: BCell
Result: Positive
Quantitative measurement: 35.8
Host: F 6-8 weeks