Reference: José M Casasnovas; Yago Margolles; María A Noriega; María Guzmán; Rocío Arranz; Roberto Melero; Mercedes Casanova; Juan Alberto Corbera; Nereida Jiménez-de-Oya; Pablo Gastaminza; Urtzi Garaigorta; Juan Carlos Saiz; Miguel Ángel Martín-Acebes; Luis Ángel Fernández. "Nanobodies Protecting From Lethal SARS-CoV-2 Infection Target Receptor Binding Epitopes Preserved in Virus Variants Other Than Omicron." Frontiers in immunology (2022).

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.001366

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.88

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 273000.0

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00106

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.96

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 345000.0

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.10 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351, K444, N448, Y449, N450, Y451, L452, Y453, R454, G482, Y489, F490, L492, Q493, S494, G496, F497, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.58

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 944000.0

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00432

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 12.9

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 476000.0

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.006136

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 1.29 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: A372, S375, D405, R408, N437, N440, V503, Q506
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 2.15 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, N448, Y449, N450, Y451, L452, L455, F456, E484, G485, Y489, F490, P491, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2162000.0

Epitope: Epitope of Nb 2.15 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, N448, Y449, N450, Y451, L452, L455, F456, E484, G485, Y489, F490, P491, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000671

Epitope: Epitope of Nb 2.15 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, N448, Y449, N450, Y451, L452, L455, F456, E484, G485, Y489, F490, P491, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 2.15 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, N448, Y449, N450, Y451, L452, L455, F456, E484, G485, Y489, F490, P491, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.39

Epitope: Epitope of Nb 2.15 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, N448, Y449, N450, Y451, L452, L455, F456, E484, G485, Y489, F490, P491, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2018000.0

Epitope: Epitope of Nb 2.15 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, N448, Y449, N450, Y451, L452, L455, F456, E484, G485, Y489, F490, P491, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000778

Epitope: Epitope of Nb 2.15 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, N448, Y449, N450, Y451, L452, L455, F456, E484, G485, Y489, F490, P491, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.31

Epitope: Epitope of Nb 2.15 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, N448, Y449, N450, Y451, L452, L455, F456, E484, G485, Y489, F490, P491, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 2.15 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, N448, Y449, N450, Y451, L452, L455, F456, E484, G485, Y489, F490, P491, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 2.15 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, N448, Y449, N450, Y451, L452, L455, F456, E484, G485, Y489, F490, P491, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of Nb 2.15 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, N448, Y449, N450, Y451, L452, L455, F456, E484, G485, Y489, F490, P491, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 2.15 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, N448, Y449, N450, Y451, L452, L455, F456, E484, G485, Y489, F490, P491, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 2.15 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, N448, Y449, N450, Y451, L452, L455, F456, E484, G485, Y489, F490, P491, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Nb 2.15 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, N448, Y449, N450, Y451, L452, L455, F456, E484, G485, Y489, F490, P491, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 2.15 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, N448, Y449, N450, Y451, L452, L455, F456, E484, G485, Y489, F490, P491, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Nb 2.15 on SARS-CoV2 S
Chemical type: Discontinuous protein residues
Discontinuous residues: G446, N448, Y449, N450, Y451, L452, L455, F456, E484, G485, Y489, F490, P491, L492, Q493, S494, Y495, G496, Q498, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive