Reference: Elisabetta Cameroni; John E Bowen; Laura E Rosen; Christian Saliba; Samantha K Zepeda; Katja Culap; Dora Pinto; Laura A VanBlargan; Anna De Marco; Julia di Iulio; Fabrizia Zatta; Hannah Kaiser; Julia Noack; Nisar Farhat; Nadine Czudnochowski; Colin Havenar-Daughton; Kaitlin R Sprouse; Josh R Dillen; Abigail E Powell; Alex Chen; Cyrus Maher; Li Yin; David Sun; Leah Soriaga; Jessica Bassi; Chiara Silacci-Fregni; Claes Gustafsson; Nicholas M Franko; Jenni Logue; Najeeha Talat Iqbal; Ignacio Mazzitelli; Jorge Geffner; Renata Grifantini; Helen Chu; Andrea Gori; Agostino Riva; Olivier Giannini; Alessandro Ceschi; Paolo Ferrari; Pietro E Cippà; Alessandra Franzetti-Pellanda; Christian Garzoni; Peter J Halfmann; Yoshihiro Kawaoka; Christy Hebner; Lisa A Purcell; Luca Piccoli; Matteo Samuele Pizzuto; Alexandra C Walls; Michael S Diamond; Amalio Telenti; Herbert W Virgin; Antonio Lanzavecchia; Gyorgy Snell; David Veesler; Davide Corti. "Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift." Nature (2022).

Epitope: Sotrovimab epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: I332, T333, N334, L335, C336, P337, G339, E340, V341, N343, A344, T345, R346, N354, K356, R357, I358, S359, N360, C361, N440, L441, R509
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Sotrovimab epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: I332, T333, N334, L335, C336, P337, G339, E340, V341, N343, A344, T345, R346, N354, K356, R357, I358, S359, N360, C361, N440, L441, R509
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Sotrovimab epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: I332, T333, N334, L335, C336, P337, G339, E340, V341, N343, A344, T345, R346, N354, K356, R357, I358, S359, N360, C361, N440, L441, R509
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Sotrovimab epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: I332, T333, N334, L335, C336, P337, G339, E340, V341, N343, A344, T345, R346, N354, K356, R357, I358, S359, N360, C361, N440, L441, R509
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: Sotrovimab epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: I332, T333, N334, L335, C336, P337, G339, E340, V341, N343, A344, T345, R346, N354, K356, R357, I358, S359, N360, C361, N440, L441, R509
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: LY-CoV016 epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: R403, D405, E406, R408, Q409, T415, G416, K417, D420, Y421, Y453, L455, F456, R457, K458, S459, N460, Y473, Q474, A475, G476, S477, F486, N487, Y489, Q493, S494, Y495, T500, N501, G502, V503, G504, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: LY-CoV555 epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: Y351,Y449, N450, L452, L455, F456, R457, T470, I472, N481, G482, V483, E484, G485, F486, N487, C488, Y489, F490, L492, Q493, S494, Y495, G496,
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: REGN10933 epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: V350, Y351, A352, W353, N354, R355, K356, R357, I358, S359, N360, I402, E484, E406, K417, Y421, Y453, L455, F456, Y473, A475, G476, S477, T478, E484, G485, F486, N487, C488, Y489, F490, L492, Q493, Q498
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: REGN10987 epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: R346, N439, N440, L441, S443, K444, V445, G446, G447, N448, Y449, N450, Q498, P499, T500
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: CT-P59 epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: R403, K417, G446, Y449, N450, L452, Y453, L455, F456, V483, E484, G485, F486, Y489, F490, L492, Q493, S494, Y495, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: COV2-2130 epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, R346, N439, N440, L441, S443, K444, V445, G446,G447, Y449, N450, L452, E484, F490, L492, Q493, S494, P499
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: COV2-2130 epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: T345, R346, N439, N440, L441, S443, K444, V445, G446,G447, Y449, N450, L452, E484, F490, L492, Q493, S494, P499
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: COV2-2196 epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: L455, F456, Q474, A475, G476, S477, T478, P479, E484, G485, F486, N487, C488, Y489, Q493
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: COV2-2196 epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: L455, F456, Q474, A475, G476, S477, T478, P479, E484, G485, F486, N487, C488, Y489, Q493
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S2K146 epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: K417, Y421, Y449, L452, L455, F456, A475, G476, T478, E484, G485, F486, N487, C488, Y489, F490, L492, Q493, S494, G496, Q498, N501, G502, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: S2K146 epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: K417, Y421, Y449, L452, L455, F456, A475, G476, T478, E484, G485, F486, N487, C488, Y489, F490, L492, Q493, S494, G496, Q498, N501, G502, Y505
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S2X259 epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, N370, S371, A372,S373, F374, S375, T376, F377, K378, C379, Y380, V382, S383, P384, T385, K386, L387, G404, D405, R408, Q409, G502, V503, G504, Q506, Y508
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low

Epitope: S2X259 epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, N370, S371, A372,S373, F374, S375, T376, F377, K378, C379, Y380, V382, S383, P384, T385, K386, L387, G404, D405, R408, Q409, G502, V503, G504, Q506, Y508
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: S2H97 epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: W353, R355, T393, N394, Y396, P426, D427, D428, F429, T430, K462, P463, F464, S514, F515, E516, L518, H519, A520, P521
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive

Epitope: S2H97 epitope on SARS-Cov2 S protein
Chemical type: Discontinuous protein residues
Discontinuous residues: W353, R355, T393, N394, Y396, P426, D427, D428, F429, T430, K462, P463, F464, S514, F515, E516, L518, H519, A520, P521
Source molecule (GenBank): P0DTC2.1
Assay category: BCell
Result: Positive-Low