Reference: Renato B Baleeiro; Louisa S Chard Dunmall; Peng Liu; Shuangshuang Lu; Yuchun Lone; Nicholas R Lemoine; Yaohe Wang. "Optimized Anchor-Modified Peptides Targeting Mutated RAS Are Promising Candidates for Immunotherapy." Frontiers in immunology (2022).

Epitope: G12A (10mer)
Chemical type: Peptide, no natural source
Sequence: KLVVVGAAGV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12A (10mer)
Chemical type: Peptide, no natural source
Sequence: KLVVVGAAGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 50220.0

Epitope: G12C (10mer)
Chemical type: Peptide, no natural source
Sequence: KLVVVGACGV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12C (10mer)
Chemical type: Peptide, no natural source
Sequence: KLVVVGACGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 95930.0

Epitope: G12R (10mer)
Chemical type: Peptide, no natural source
Sequence: KLVVVGARGV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12R (10mer)
Chemical type: Peptide, no natural source
Sequence: KLVVVGARGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 151200.0

Epitope: G12S (10mer)
Chemical type: Peptide, no natural source
Sequence: KLVVVGASGV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12S (10mer)
Chemical type: Peptide, no natural source
Sequence: KLVVVGASGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 71960.0

Epitope: G12V (10mer)
Chemical type: Peptide, no natural source
Sequence: KLVVVGAVGV
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V (10mer)
Chemical type: Peptide, no natural source
Sequence: KLVVVGAVGV
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V (10mer)
Chemical type: Peptide, no natural source
Sequence: KLVVVGAVGV
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V (10mer)
Chemical type: Peptide, no natural source
Sequence: KLVVVGAVGV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V (10mer)
Chemical type: Peptide, no natural source
Sequence: KLVVVGAVGV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V (10mer)
Chemical type: Peptide, no natural source
Sequence: KLVVVGAVGV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 35810.0

Epitope: G12A 9mer
Chemical type: Peptide, no natural source
Sequence: LLVVGAAGV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 17540.0

Epitope: G12C 9mer
Chemical type: Peptide, no natural source
Sequence: LLVVGACGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 73460.0

Epitope: G12D 9mer
Chemical type: Peptide, no natural source
Sequence: LLVVGADGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 83380.0

Epitope: G12R 9mer
Chemical type: Peptide, no natural source
Sequence: LLVVGARGV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 23700.0

Epitope: G12S 9mer
Chemical type: Peptide, no natural source
Sequence: LLVVGASGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 90570.0

Epitope: G12V  9mer
Chemical type: Peptide, no natural source
Sequence: LLVVGAVGV
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: G12V  9mer
Chemical type: Peptide, no natural source
Sequence: LLVVGAVGV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V  9mer
Chemical type: Peptide, no natural source
Sequence: LLVVGAVGV
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V  9mer
Chemical type: Peptide, no natural source
Sequence: LLVVGAVGV
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V  9mer
Chemical type: Peptide, no natural source
Sequence: LLVVGAVGV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V  9mer
Chemical type: Peptide, no natural source
Sequence: LLVVGAVGV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 25560.0

Epitope: G12R 10mer Anchor-modified
Chemical type: Peptide, no natural source
Sequence: LLVVVGARGV
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 6550.0

Epitope: G12D 9mer Original
Chemical type: Peptide, no natural source
Sequence: LVVVGADGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 453000.0

Epitope: G12R 9mer Original
Chemical type: Peptide, no natural source
Sequence: LVVVGARGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 429000.0

Epitope: G12S 9mer Original
Chemical type: Peptide, no natural source
Sequence: LVVVGASGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 580500.0

Epitope: G12V 9mer Original
Chemical type: Peptide, no natural source
Sequence: LVVVGAVGV
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: G12V 9mer Original
Chemical type: Peptide, no natural source
Sequence: LVVVGAVGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 610000.0

Epitope: G12A (9mer)
Chemical type: Peptide, no natural source
Sequence: VVGAAGVGK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12A (9mer)
Chemical type: Peptide, no natural source
Sequence: VVGAAGVGK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12A (9mer)
Chemical type: Peptide, no natural source
Sequence: VVGAAGVGK
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 277200.0

Epitope: G12A (9mer)
Chemical type: Peptide, no natural source
Sequence: VVGAAGVGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 11230.0

Epitope: G12C (9mer)
Chemical type: Peptide, no natural source
Sequence: VVGACGVGK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12C (9mer)
Chemical type: Peptide, no natural source
Sequence: VVGACGVGK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12C (9mer)
Chemical type: Peptide, no natural source
Sequence: VVGACGVGK
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 828300.0

Epitope: G12C (9mer)
Chemical type: Peptide, no natural source
Sequence: VVGACGVGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 29080.0

Epitope: G12V (9mer)
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V (9mer)
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V (9mer)
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 110100.0

Epitope: G12V (9mer)
Chemical type: Peptide, no natural source
Sequence: VVGAVGVGK
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 5071.0

Epitope: G12C (10mer)
Chemical type: Peptide, no natural source
Sequence: VVVGACGVGK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12C (10mer)
Chemical type: Peptide, no natural source
Sequence: VVVGACGVGK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12C (10mer)
Chemical type: Peptide, no natural source
Sequence: VVVGACGVGK
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 142600.0

Epitope: G12C (10mer)
Chemical type: Peptide, no natural source
Sequence: VVVGACGVGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 15630.0

Epitope: G12D (10mer)
Chemical type: Peptide, no natural source
Sequence: VVVGADGVGK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12D (10mer)
Chemical type: Peptide, no natural source
Sequence: VVVGADGVGK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12D (10mer)
Chemical type: Peptide, no natural source
Sequence: VVVGADGVGK
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 998800.0

Epitope: G12D (10mer)
Chemical type: Peptide, no natural source
Sequence: VVVGADGVGK
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 15030.0

Epitope: G12V (10mer)
Chemical type: Peptide, no natural source
Sequence: VVVGAVGVGK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V (10mer)
Chemical type: Peptide, no natural source
Sequence: VVVGAVGVGK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V (10mer)
Chemical type: Peptide, no natural source
Sequence: VVVGAVGVGK
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 63910.0

Epitope: G12V (10mer)
Chemical type: Peptide, no natural source
Sequence: VVVGAVGVGK
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 6954.0

Epitope: G12A 9mer
Chemical type: Peptide, no natural source
Sequence: YLVVGAAGV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 16410.0

Epitope: G12C 9mer
Chemical type: Peptide, no natural source
Sequence: YLVVGACGV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 26090.0

Epitope: G12D 9mer
Chemical type: Peptide, no natural source
Sequence: YLVVGADGV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 13420.0

Epitope: G12R 9mer
Chemical type: Peptide, no natural source
Sequence: YLVVGARGV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 15600.0

Epitope: G12S 9mer
Chemical type: Peptide, no natural source
Sequence: YLVVGASGV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 21170.0

Epitope: G12A 10mer Anchor-modified
Chemical type: Peptide, no natural source
Sequence: YLVVVGAAGV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 27740.0

Epitope: G12C 10mer Anchor-modified
Chemical type: Peptide, no natural source
Sequence: YLVVVGACGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 95490.0

Epitope: G12D 10mer Anchor-modified
Chemical type: Peptide, no natural source
Sequence: YLVVVGADGV
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 5683.0

Epitope: G12S 10mer Anchor-modified
Chemical type: Peptide, no natural source
Sequence: YLVVVGASGV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10650.0

Epitope: G12V 10mer Anchor-modified
Chemical type: Peptide, no natural source
Sequence: YLVVVGAVGV
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V 10mer Anchor-modified
Chemical type: Peptide, no natural source
Sequence: YLVVVGAVGV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V 10mer Anchor-modified
Chemical type: Peptide, no natural source
Sequence: YLVVVGAVGV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 15470.0

Epitope: G12A 9mer Anchor-modified
Chemical type: Peptide, no natural source
Sequence: YVVVGAAGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 116700.0

Epitope: G12C 9mer Anchor-modified
Chemical type: Peptide, no natural source
Sequence: YVVVGACGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 137600.0

Epitope: G12D 9mer Anchor-modified
Chemical type: Peptide, no natural source
Sequence: YVVVGADGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 199300.0

Epitope: G12R 9mer Anchor-modified
Chemical type: Peptide, no natural source
Sequence: YVVVGARGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 51620.0

Epitope: G12S 9mer Anchor-modified
Chemical type: Peptide, no natural source
Sequence: YVVVGASGV
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 206700.0

Epitope: G12V 9mer Anchor-modified
Chemical type: Peptide, no natural source
Sequence: YVVVGAVGV
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V 9mer Anchor-modified
Chemical type: Peptide, no natural source
Sequence: YVVVGAVGV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12V 9mer Anchor-modified
Chemical type: Peptide, no natural source
Sequence: YVVVGAVGV
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 28260.0

Epitope: WT-9mer
Chemical type: Peptide from protein
Sequence: LVVVGAGGV
Position: 6-14
Source molecule (GenBank): G3V4K2.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 31-mer G12V RAS
Chemical type: Peptide, no natural source
Sequence: MTEYKLLVVGAVGVGKSALTIQLIQNHFVDE
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 31-mer G12V RAS
Chemical type: Peptide, no natural source
Sequence: MTEYKLLVVGAVGVGKSALTIQLIQNHFVDE
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: G12A 9mer Original
Chemical type: Peptide from protein
Sequence: LVVVGAAGV
Position: 6-14
Source molecule (GenBank): UBF41787.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 191100.0

Epitope: G12R (9mer)
Chemical type: Peptide from protein
Sequence: VVGARGVGK
Position: 421-429
Source molecule (GenBank): Q8IXI1.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12R (9mer)
Chemical type: Peptide from protein
Sequence: VVGARGVGK
Position: 421-429
Source molecule (GenBank): Q8IXI1.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12R (9mer)
Chemical type: Peptide from protein
Sequence: VVGARGVGK
Position: 421-429
Source molecule (GenBank): Q8IXI1.2
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 695200.0

Epitope: G12R (9mer)
Chemical type: Peptide from protein
Sequence: VVGARGVGK
Position: 421-429
Source molecule (GenBank): Q8IXI1.2
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 156600.0

Epitope: G12S (9mer)
Chemical type: Peptide from protein
Sequence: VVGASGVGK
Position: 38-46
Source molecule (GenBank): Q9BPW5.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12S (9mer)
Chemical type: Peptide from protein
Sequence: VVGASGVGK
Position: 38-46
Source molecule (GenBank): Q9BPW5.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12S (9mer)
Chemical type: Peptide from protein
Sequence: VVGASGVGK
Position: 38-46
Source molecule (GenBank): Q9BPW5.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 174200.0

Epitope: G12S (9mer)
Chemical type: Peptide from protein
Sequence: VVGASGVGK
Position: 38-46
Source molecule (GenBank): Q9BPW5.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 12710.0

Epitope: G12S (10mer)
Chemical type: Peptide from protein
Sequence: VVVGASGVGK
Position: 45-54
Source molecule (GenBank): Q7Z444.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12S (10mer)
Chemical type: Peptide from protein
Sequence: VVVGASGVGK
Position: 45-54
Source molecule (GenBank): Q7Z444.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: G12S (10mer)
Chemical type: Peptide from protein
Sequence: VVVGASGVGK
Position: 45-54
Source molecule (GenBank): Q7Z444.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 78040.0

Epitope: G12S (10mer)
Chemical type: Peptide from protein
Sequence: VVVGASGVGK
Position: 45-54
Source molecule (GenBank): Q7Z444.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10230.0