Reference: Julie A Hixon; Caroline Andrews; Lila Kashi; Casey L Kohnhorst; Emilee Senkevitch; Kelli Czarra; Joao T Barata; Wenqing Li; Joel P Schneider; Scott T R Walsh; Scott K Durum. "New anti-IL-7Rα monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models." Leukemia (2020).

Epitope: Epitope of 4A10 Fab on IL-7Rα
Chemical type: Discontinuous protein residues
Discontinuous residues: E72, C74, G75, E79, K81, C82, K104, S105, N106, C108, K110, E113, K114, S115, C118, K120
Source molecule (GenBank): NP_002176.2
Assay category: BCell
Result: Positive
Quantitative measurement: 1.0

Epitope: Epitope of 4A10 Fab on IL-7Rα
Chemical type: Discontinuous protein residues
Discontinuous residues: E72, C74, G75, E79, K81, C82, K104, S105, N106, C108, K110, E113, K114, S115, C118, K120
Source molecule (GenBank): NP_002176.2
Assay category: BCell
Result: Positive
Quantitative measurement: 260000.0

Epitope: Epitope of 4A10 Fab on IL-7Rα
Chemical type: Discontinuous protein residues
Discontinuous residues: E72, C74, G75, E79, K81, C82, K104, S105, N106, C108, K110, E113, K114, S115, C118, K120
Source molecule (GenBank): NP_002176.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00027

Epitope: Epitope of 4A10 Fab on IL-7Rα
Chemical type: Discontinuous protein residues
Discontinuous residues: E72, C74, G75, E79, K81, C82, K104, S105, N106, C108, K110, E113, K114, S115, C118, K120
Source molecule (GenBank): NP_002176.2
Assay category: BCell
Result: Positive

Epitope: Epitope of 4A10 Fab on IL-7Rα
Chemical type: Discontinuous protein residues
Discontinuous residues: E72, C74, G75, E79, K81, C82, K104, S105, N106, C108, K110, E113, K114, S115, C118, K120
Source molecule (GenBank): NP_002176.2
Assay category: BCell
Result: Positive

Epitope: Epitope of 4A10 Fab on IL-7Rα
Chemical type: Discontinuous protein residues
Discontinuous residues: E72, C74, G75, E79, K81, C82, K104, S105, N106, C108, K110, E113, K114, S115, C118, K120
Source molecule (GenBank): NP_002176.2
Assay category: BCell
Result: Positive

Epitope: Epitope of 4A10 Fab on IL-7Rα
Chemical type: Discontinuous protein residues
Discontinuous residues: E72, C74, G75, E79, K81, C82, K104, S105, N106, C108, K110, E113, K114, S115, C118, K120
Source molecule (GenBank): NP_002176.2
Assay category: BCell
Result: Positive

Epitope: Epitope of 4A10 Fab on IL-7Rα
Chemical type: Discontinuous protein residues
Discontinuous residues: E72, C74, G75, E79, K81, C82, K104, S105, N106, C108, K110, E113, K114, S115, C118, K120
Source molecule (GenBank): NP_002176.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2.9

Epitope: Epitope of 2B8 Fab on IL-7Rα
Chemical type: Discontinuous protein residues
Discontinuous residues: D134, L135, S136, V137, V138, Y139, R140, E141, G142, T149, M200, Y224, Y225, F226, R227, P229
Source molecule (GenBank): NP_002176.2
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00012

Epitope: Epitope of 2B8 Fab on IL-7Rα
Chemical type: Discontinuous protein residues
Discontinuous residues: D134, L135, S136, V137, V138, Y139, R140, E141, G142, T149, M200, Y224, Y225, F226, R227, P229
Source molecule (GenBank): NP_002176.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2.9

Epitope: Epitope of 2B8 Fab on IL-7Rα
Chemical type: Discontinuous protein residues
Discontinuous residues: D134, L135, S136, V137, V138, Y139, R140, E141, G142, T149, M200, Y224, Y225, F226, R227, P229
Source molecule (GenBank): NP_002176.2
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B8 Fab on IL-7Rα
Chemical type: Discontinuous protein residues
Discontinuous residues: D134, L135, S136, V137, V138, Y139, R140, E141, G142, T149, M200, Y224, Y225, F226, R227, P229
Source molecule (GenBank): NP_002176.2
Assay category: BCell
Result: Positive
Quantitative measurement: 8.7

Epitope: Epitope of 2B8 Fab on IL-7Rα
Chemical type: Discontinuous protein residues
Discontinuous residues: D134, L135, S136, V137, V138, Y139, R140, E141, G142, T149, M200, Y224, Y225, F226, R227, P229
Source molecule (GenBank): NP_002176.2
Assay category: BCell
Result: Positive
Quantitative measurement: 14000.0

Epitope: Epitope of 2B8 Fab on IL-7Rα
Chemical type: Discontinuous protein residues
Discontinuous residues: D134, L135, S136, V137, V138, Y139, R140, E141, G142, T149, M200, Y224, Y225, F226, R227, P229
Source molecule (GenBank): NP_002176.2
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B8 Fab on IL-7Rα
Chemical type: Discontinuous protein residues
Discontinuous residues: D134, L135, S136, V137, V138, Y139, R140, E141, G142, T149, M200, Y224, Y225, F226, R227, P229
Source molecule (GenBank): NP_002176.2
Assay category: BCell
Result: Positive-Intermediate