Reference: Robyn S Lymbury; Colleen Olive; Kellie A Powell; Michael F Good; Robert G Hirst; Justin T LaBrooy; Natkunam Ketheesan. "Induction of autoimmune valvulitis in Lewis rats following immunization with peptides from the conserved region of group A streptococcal M protein." Journal of autoimmunity (2003).

Epitope: Group A streptococcal M protein peptide 145
Chemical type: Peptide from protein
Sequence: LRRDLDASREAKKQVEKALE
Position: 321-340
Source molecule (GenBank): AAP32473.1
Assay category: TCell
Result: Negative
Host: F 10 weeks
Cell type: mononuclear cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Group A streptococcal M protein peptide 146
Chemical type: Peptide from protein
Sequence: AKKQVEKALEEANSLKAALE
Assay category: TCell
Result: Positive-Low
Host: F 10 weeks
Cell type: mononuclear cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Group A streptococcal M protein peptide 147
Chemical type: Peptide from protein
Sequence: EANSKLAALEKLNKELEESK
Position: 341-360
Source molecule (GenBank): AAP32473.1
Assay category: TCell
Result: Negative
Host: F 10 weeks
Cell type: mononuclear cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Group A streptococcal M protein peptide 148
Chemical type: Peptide from protein
Sequence: KLNKELEESKKLTEKEKAEL
Position: 351-370
Source molecule (GenBank): AAP32473.1
Assay category: TCell
Result: Negative
Host: F 10 weeks
Cell type: mononuclear cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Group A streptococcal M protein peptide 149
Chemical type: Peptide from protein
Sequence: KLTEKEKAELQAKLEAEAKA
Position: 361-380
Source molecule (GenBank): AAP32473.1
Assay category: TCell
Result: Negative
Host: F 10 weeks
Cell type: mononuclear cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Group A streptococcal M protein peptide 150
Chemical type: Peptide from protein
Sequence: QAKLEAEAKALKEQLAKQAE
Position: 371-390
Source molecule (GenBank): AAP32473.1
Assay category: TCell
Result: Positive
Host: F 10 weeks
Cell type: mononuclear cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Group A streptococcal M protein peptide 151
Chemical type: Peptide from protein
Sequence: LKEQLAKQAEELAKLRAGKA
Position: 381-400
Source molecule (GenBank): AAP32473.1
Assay category: TCell
Result: Negative
Host: F 10 weeks
Cell type: mononuclear cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Group A streptococcal M protein peptide 152
Chemical type: Peptide from protein
Sequence: ELAKLRAGKASDSQTPDTKP
Position: 391-410
Source molecule (GenBank): AAP32473.1
Assay category: TCell
Result: Negative
Host: F 10 weeks
Cell type: mononuclear cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Group A streptococcal M protein peptide 153
Chemical type: Peptide from protein
Sequence: SDSQTPDTKPGNKAVPGKGQ
Position: 401-420
Source molecule (GenBank): AAP32473.1
Assay category: TCell
Result: Positive-Low
Host: F 10 weeks
Cell type: mononuclear cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Group A streptococcal M protein peptide 154
Chemical type: Peptide from protein
Sequence: GNKAVPGKGQAPQAGTKPNQ
Position: 411-430
Source molecule (GenBank): AAP32473.1
Assay category: TCell
Result: Negative
Host: F 10 weeks
Cell type: mononuclear cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Group A streptococcal M protein peptide 155
Chemical type: Peptide from protein
Sequence: APQAGTKPNQNKAPMKETKR
Position: 421-440
Source molecule (GenBank): AAP32473.1
Assay category: TCell
Result: Negative
Host: F 10 weeks
Cell type: mononuclear cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Group A streptococcal M protein peptide 156
Chemical type: Peptide from protein
Sequence: NKAPMKETKRQLPSTGETAN
Position: 431-450
Source molecule (GenBank): AAP32473.1
Assay category: TCell
Result: Negative
Host: F 10 weeks
Cell type: mononuclear cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Group A streptococcal M protein peptide 157
Chemical type: Peptide from protein
Sequence: QLPSTGETANPFFTAAALTV
Position: 441-460
Source molecule (GenBank): AAP32473.1
Assay category: TCell
Result: Positive
Host: F 10 weeks
Cell type: mononuclear cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Group A streptococcal M protein peptide 158
Chemical type: Peptide from protein
Sequence: PFFTAAALTVMATAGVAAVV
Position: 533-552
Source molecule (GenBank): Q54718
Assay category: TCell
Result: Negative
Host: F 10 weeks
Cell type: mononuclear cell
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Group A streptococcal M protein peptide 159
Chemical type: Peptide from protein
Sequence: MATAGVAAVVKRKEEN
Position: 543-558
Source molecule (GenBank): Q54718
Assay category: TCell
Result: Positive
Host: F 10 weeks
Cell type: mononuclear cell
Tissue: spleen
Culture conditions: Direct Ex Vivo