Reference: Takeo Kuwata; Yu Kaku; Shashwata Biswas; Kaho Matsumoto; Mikiko Shimizu; Yoko Kawanami; Ryuta Uraki; Kyo Okazaki; Rumi Minami; Yoji Nagasaki; Mami Nagashima; Isao Yoshida; Kenji Sadamasu; Kazuhisa Yoshimura; Mutsumi Ito; Maki Kiso; Seiya Yamayoshi; Masaki Imai; Terumasa Ikeda; Kei Sato; Mako Toyoda; Takamasa Ueno; Takako Inoue; Yasuhito Tanaka; Kanako Tarakado Kimura; Takao Hashiguchi; Yukihiko Sugita; Takeshi Noda; Hiroshi Morioka; Yoshihiro Kawaoka; Shuzo Matsushita. "Induction of IGHV3-53 public antibodies with broadly neutralising activity against SARS-CoV-2 including Omicron subvariants in a Delta breakthrough infection case." EBioMedicine (2024).

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-Intermediate
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-Intermediate
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-Intermediate
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-Low
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-Intermediate
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-Intermediate
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00064
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Quantitative measurement: 0.00000010
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Quantitative measurement: 350000.0
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive
Quantitative measurement: 8.9
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive
Quantitative measurement: 72000.0
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-Low
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-Intermediate
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Quantitative measurement: 0.00010
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-Intermediate
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-Low
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-Intermediate
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-Low
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-Intermediate
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Host: F 26 years

Epitope: Epitope of mAb K4-66 on Omicron XBB.1.5 S
Chemical type: Discontinuous protein residues
Discontinuous residues: L451, F452, Q489
Source molecule (GenBank): WBW01504.1
Assay category: BCell
Result: Positive-High
Host: F 26 years