Reference: Timothy C Cheung; Shane Atwell; Lisa Bafetti; Paulina Delgado Cuenca; Karen Froning; Jorg Hendle; Michael Hickey; Carolyn Ho; Jiawen Huang; Ricky Lieu; Stacie Lim; David Lippner; Victor Obungu; Lindsay Ward-Kavanagh; Kenneth Weichert; Carl F Ware; Andrew C Vendel. "Epitope topography of agonist antibodies to the checkpoint inhibitory receptor BTLA." Structure (London, England : 1993) (2023).

Epitope: Epitope of 25F7 Fab on BTLA
Chemical type: Discontinuous protein residues
Discontinuous residues: N65, R66, H68, Q86, T87, S88, W89, K90, E91, N118
Source molecule (GenBank): Q7Z6A9.3
Assay category: BCell
Result: Positive

Epitope: Epitope of 25F7 Fab on BTLA
Chemical type: Discontinuous protein residues
Discontinuous residues: N65, R66, H68, Q86, T87, S88, W89, K90, E91, N118
Source molecule (GenBank): Q7Z6A9.3
Assay category: BCell
Result: Positive

Epitope: Epitope of 25F7 Fab on BTLA
Chemical type: Discontinuous protein residues
Discontinuous residues: N65, R66, H68, Q86, T87, S88, W89, K90, E91, N118
Source molecule (GenBank): Q7Z6A9.3
Assay category: BCell
Result: Positive
Quantitative measurement: 1.85

Epitope: Epitope of 25F7 Fab on BTLA
Chemical type: Discontinuous protein residues
Discontinuous residues: N65, R66, H68, Q86, T87, S88, W89, K90, E91, N118
Source molecule (GenBank): Q7Z6A9.3
Assay category: BCell
Result: Positive
Quantitative measurement: 1.62

Epitope: Epitope of 25F7 Fab on BTLA
Chemical type: Discontinuous protein residues
Discontinuous residues: N65, R66, H68, Q86, T87, S88, W89, K90, E91, N118
Source molecule (GenBank): Q7Z6A9.3
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of 25F7 Fab on BTLA
Chemical type: Discontinuous protein residues
Discontinuous residues: N65, R66, H68, Q86, T87, S88, W89, K90, E91, N118
Source molecule (GenBank): Q7Z6A9.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.357

Epitope: Epitope of 25F7 Fab on BTLA
Chemical type: Discontinuous protein residues
Discontinuous residues: N65, R66, H68, Q86, T87, S88, W89, K90, E91, N118
Source molecule (GenBank): Q7Z6A9.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.867

Epitope: Epitope of 22B3 Fab on BTLA
Chemical type: Discontinuous protein residues
Discontinuous residues: D35, Q37, L38, Y39, I40, K41, R42, L74, G76, T77, T78, R114, F119, Q120, S121, N122, L123, I124, E125, S126, H127, S128
Source molecule (GenBank): Q7Z6A9.3
Assay category: BCell
Result: Positive

Epitope: Epitope of 22B3 Fab on BTLA
Chemical type: Discontinuous protein residues
Discontinuous residues: D35, Q37, L38, Y39, I40, K41, R42, L74, G76, T77, T78, R114, F119, Q120, S121, N122, L123, I124, E125, S126, H127, S128
Source molecule (GenBank): Q7Z6A9.3
Assay category: BCell
Result: Positive-High

Epitope: Epitope of 22B3 Fab on BTLA
Chemical type: Discontinuous protein residues
Discontinuous residues: D35, Q37, L38, Y39, I40, K41, R42, L74, G76, T77, T78, R114, F119, Q120, S121, N122, L123, I124, E125, S126, H127, S128
Source molecule (GenBank): Q7Z6A9.3
Assay category: BCell
Result: Positive

Epitope: Epitope of 22B3 Fab on BTLA
Chemical type: Discontinuous protein residues
Discontinuous residues: D35, Q37, L38, Y39, I40, K41, R42, L74, G76, T77, T78, R114, F119, Q120, S121, N122, L123, I124, E125, S126, H127, S128
Source molecule (GenBank): Q7Z6A9.3
Assay category: BCell
Result: Positive
Quantitative measurement: 2.31

Epitope: Epitope of 22B3 Fab on BTLA
Chemical type: Discontinuous protein residues
Discontinuous residues: D35, Q37, L38, Y39, I40, K41, R42, L74, G76, T77, T78, R114, F119, Q120, S121, N122, L123, I124, E125, S126, H127, S128
Source molecule (GenBank): Q7Z6A9.3
Assay category: BCell
Result: Positive
Quantitative measurement: 57.1

Epitope: Epitope of 22B3 Fab on BTLA
Chemical type: Discontinuous protein residues
Discontinuous residues: D35, Q37, L38, Y39, I40, K41, R42, L74, G76, T77, T78, R114, F119, Q120, S121, N122, L123, I124, E125, S126, H127, S128
Source molecule (GenBank): Q7Z6A9.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.365

Epitope: Epitope of 22B3 Fab on BTLA
Chemical type: Discontinuous protein residues
Discontinuous residues: D35, Q37, L38, Y39, I40, K41, R42, L74, G76, T77, T78, R114, F119, Q120, S121, N122, L123, I124, E125, S126, H127, S128
Source molecule (GenBank): Q7Z6A9.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.274

Epitope: Epitope of 22B3 Fab on BTLA
Chemical type: Discontinuous protein residues
Discontinuous residues: D35, Q37, L38, Y39, I40, K41, R42, L74, G76, T77, T78, R114, F119, Q120, S121, N122, L123, I124, E125, S126, H127, S128
Source molecule (GenBank): Q7Z6A9.3
Assay category: BCell
Result: Positive