Reference: Henrik Østergaard; Jacob Lund; Per J Greisen; Stine Kjellev; Anette Henriksen; Nikolai Lorenzen; Eva Johansson; Gustav Røder; Morten G Rasch; Laust B Johnsen; Thomas Egebjerg; Søren Lund; Henrik Rahbek-Nielsen; Prafull S Gandhi; Kasper Lamberth; Mette Loftager; Lisbeth M Andersen; Amalie C Bonde; Fabian Stavenuiter; Daniel E Madsen; Xun Li; Thomas L Holm; Carsten D Ley; Peter Thygesen; Haisun Zhu; Rong Zhou; Karina Thorn; Zhiru Yang; Mette B Hermit; Jais R Bjelke; Bjarne G Hansen; Ida Hilden. "A factor VIIIa-mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice." Blood (2021).

Epitope: Epitope of Mim8 anti-FIXa
Chemical type: Discontinuous protein residues
Discontinuous residues: A380, T381, L383, R384, S385, T386, K387,F388, T389, H400
Source molecule (GenBank): P00740.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Mim8 anti-FIXa
Chemical type: Discontinuous protein residues
Discontinuous residues: A380, T381, L383, R384, S385, T386, K387,F388, T389, H400
Source molecule (GenBank): P00740.2
Assay category: BCell
Result: Positive
Quantitative measurement: 3.1

Epitope: Epitope of Mim8 anti-FIXa
Chemical type: Discontinuous protein residues
Discontinuous residues: A380, T381, L383, R384, S385, T386, K387,F388, T389, H400
Source molecule (GenBank): P00740.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Mim8 anti-FIXa
Chemical type: Discontinuous protein residues
Discontinuous residues: A380, T381, L383, R384, S385, T386, K387,F388, T389, H400
Source molecule (GenBank): P00740.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Mim8 anti-FIXa
Chemical type: Discontinuous protein residues
Discontinuous residues: A380, T381, L383, R384, S385, T386, K387,F388, T389, H400
Source molecule (GenBank): P00740.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2300.0

Epitope: Epitope of Mim8 anti-FX
Chemical type: Region on multi-chain protein
Discontinuous residues: C: S267, E268, F269, Y270, E306, R327, P331, L343, P344, E345, L459, K460, D463, R464, M466, K467, T468; D: E143, R153, T156, L157, A158, D159, I165, T167, G168, P169
Source molecule (GenBank): P00742.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Mim8 anti-FX
Chemical type: Region on multi-chain protein
Discontinuous residues: C: S267, E268, F269, Y270, E306, R327, P331, L343, P344, E345, L459, K460, D463, R464, M466, K467, T468; D: E143, R153, T156, L157, A158, D159, I165, T167, G168, P169
Source molecule (GenBank): P00742.2
Assay category: BCell
Result: Positive
Quantitative measurement: 2.6

Epitope: Epitope of Mim8 anti-FX
Chemical type: Region on multi-chain protein
Discontinuous residues: C: S267, E268, F269, Y270, E306, R327, P331, L343, P344, E345, L459, K460, D463, R464, M466, K467, T468; D: E143, R153, T156, L157, A158, D159, I165, T167, G168, P169
Source molecule (GenBank): P00742.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Mim8 anti-FX
Chemical type: Region on multi-chain protein
Discontinuous residues: C: S267, E268, F269, Y270, E306, R327, P331, L343, P344, E345, L459, K460, D463, R464, M466, K467, T468; D: E143, R153, T156, L157, A158, D159, I165, T167, G168, P169
Source molecule (GenBank): P00742.2
Assay category: BCell
Result: Positive

Epitope: Epitope of Mim8 anti-FX
Chemical type: Region on multi-chain protein
Discontinuous residues: C: S267, E268, F269, Y270, E306, R327, P331, L343, P344, E345, L459, K460, D463, R464, M466, K467, T468; D: E143, R153, T156, L157, A158, D159, I165, T167, G168, P169
Source molecule (GenBank): P00742.2
Assay category: BCell
Result: Positive
Quantitative measurement: 300.0