Reference: Yiyuan Yin; Stevan Djakovic; Scot Marsters; Janet Tien; Jing Peng; Jarrod Tremayne; Genee Lee; Richard M Neve; Yan Wu; Mark Merchant; Avi Ashkenazi; Paul J Carter. "Redesigning a Monospecific Anti-FGFR3 Antibody to Add Selectivity for FGFR2 and Expand Antitumor Activity." Molecular cancer therapeutics (2015).

Epitope: Epitope of 2B.1.3 Fab on FGFR2 IIIb
Chemical type: Discontinuous protein residues
Discontinuous residues: T157, N158, K161, K164, L166, H167, P170, A171, A172, N173, T174, V175, K176, R178, P180, K208, R210, H213, I217, E219, Y244, R251
Source molecule (GenBank): P21802.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B.1.3 Fab on FGFR2 IIIb
Chemical type: Discontinuous protein residues
Discontinuous residues: T157, N158, K161, K164, L166, H167, P170, A171, A172, N173, T174, V175, K176, R178, P180, K208, R210, H213, I217, E219, Y244, R251
Source molecule (GenBank): P21802.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.1

Epitope: Epitope of 2B.1.3 Fab on FGFR2 IIIb
Chemical type: Discontinuous protein residues
Discontinuous residues: T157, N158, K161, K164, L166, H167, P170, A171, A172, N173, T174, V175, K176, R178, P180, K208, R210, H213, I217, E219, Y244, R251
Source molecule (GenBank): P21802.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B.1.3 Fab on FGFR2 IIIb
Chemical type: Discontinuous protein residues
Discontinuous residues: T157, N158, K161, K164, L166, H167, P170, A171, A172, N173, T174, V175, K176, R178, P180, K208, R210, H213, I217, E219, Y244, R251
Source molecule (GenBank): P21802.1
Assay category: BCell
Result: Positive
Quantitative measurement: 32.0

Epitope: Epitope of 2B.1.3 Fab on FGFR2 IIIb
Chemical type: Discontinuous protein residues
Discontinuous residues: T157, N158, K161, K164, L166, H167, P170, A171, A172, N173, T174, V175, K176, R178, P180, K208, R210, H213, I217, E219, Y244, R251
Source molecule (GenBank): P21802.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B.1.3 Fab on FGFR2 IIIb
Chemical type: Discontinuous protein residues
Discontinuous residues: T157, N158, K161, K164, L166, H167, P170, A171, A172, N173, T174, V175, K176, R178, P180, K208, R210, H213, I217, E219, Y244, R251
Source molecule (GenBank): P21802.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.0

Epitope: Epitope of 2B.1.3 Fab on FGFR2 IIIb
Chemical type: Discontinuous protein residues
Discontinuous residues: T157, N158, K161, K164, L166, H167, P170, A171, A172, N173, T174, V175, K176, R178, P180, K208, R210, H213, I217, E219, Y244, R251
Source molecule (GenBank): P21802.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B.1.3 Fab on FGFR2 IIIb
Chemical type: Discontinuous protein residues
Discontinuous residues: T157, N158, K161, K164, L166, H167, P170, A171, A172, N173, T174, V175, K176, R178, P180, K208, R210, H213, I217, E219, Y244, R251
Source molecule (GenBank): P21802.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.36

Epitope: Epitope of 2B.1.3 Fab on FGFR2 IIIb
Chemical type: Discontinuous protein residues
Discontinuous residues: T157, N158, K161, K164, L166, H167, P170, A171, A172, N173, T174, V175, K176, R178, P180, K208, R210, H213, I217, E219, Y244, R251
Source molecule (GenBank): P21802.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B.1.3 Fab on FGFR2 IIIb
Chemical type: Discontinuous protein residues
Discontinuous residues: T157, N158, K161, K164, L166, H167, P170, A171, A172, N173, T174, V175, K176, R178, P180, K208, R210, H213, I217, E219, Y244, R251
Source molecule (GenBank): P21802.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 2B.1.3 Fab on FGFR2 IIIb
Chemical type: Discontinuous protein residues
Discontinuous residues: T157, N158, K161, K164, L166, H167, P170, A171, A172, N173, T174, V175, K176, R178, P180, K208, R210, H213, I217, E219, Y244, R251
Source molecule (GenBank): P21802.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.6

Epitope: Epitope of 2B.1.3 Fab on FGFR2 IIIb
Chemical type: Discontinuous protein residues
Discontinuous residues: T157, N158, K161, K164, L166, H167, P170, A171, A172, N173, T174, V175, K176, R178, P180, K208, R210, H213, I217, E219, Y244, R251
Source molecule (GenBank): P21802.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.0

Epitope: Epitope of 2B.1.3 Fab on FGFR2 IIIb
Chemical type: Discontinuous protein residues
Discontinuous residues: T157, N158, K161, K164, L166, H167, P170, A171, A172, N173, T174, V175, K176, R178, P180, K208, R210, H213, I217, E219, Y244, R251
Source molecule (GenBank): P21802.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.09

Epitope: Epitope of 2B.1.3 Fab on FGFR2 IIIb
Chemical type: Discontinuous protein residues
Discontinuous residues: T157, N158, K161, K164, L166, H167, P170, A171, A172, N173, T174, V175, K176, R178, P180, K208, R210, H213, I217, E219, Y244, R251
Source molecule (GenBank): P21802.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.07