Reference: J H Robinson; M C Atherton; J A Goodacre; M Pinkney; H Weightman; M A Kehoe. "Mapping T-cell epitopes in group A streptococcal type 5 M protein." Infection and immunity (1991).

Epitope: sM5 [1-35]
Chemical type: Peptide from protein
Sequence: AVTRGTINDPQRAKEALDKYELENHDLKTKNEGLK
Position: 43-77
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [1-35]
Chemical type: Peptide from protein
Sequence: AVTRGTINDPQRAKEALDKYELENHDLKTKNEGLK
Position: 43-77
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [1-35]
Chemical type: Peptide from protein
Sequence: AVTRGTINDPQRAKEALDKYELENHDLKTKNEGLK
Position: 43-77
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [1-35]
Chemical type: Peptide from protein
Sequence: AVTRGTINDPQRAKEALDKYELENHDLKTKNEGLK
Position: 43-77
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [1-35]
Chemical type: Peptide from protein
Sequence: AVTRGTINDPQRAKEALDKYELENHDLKTKNEGLK
Position: 43-77
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [28-54]
Chemical type: Peptide from protein
Sequence: KTKNEGLKTENEGLKTENEGLKTENEG
Position: 70-96
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [28-54]
Chemical type: Peptide from protein
Sequence: KTKNEGLKTENEGLKTENEGLKTENEG
Position: 70-96
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [28-54]
Chemical type: Peptide from protein
Sequence: KTKNEGLKTENEGLKTENEGLKTENEG
Position: 70-96
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [28-54]
Chemical type: Peptide from protein
Sequence: KTKNEGLKTENEGLKTENEGLKTENEG
Position: 70-96
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [28-54]
Chemical type: Peptide from protein
Sequence: KTKNEGLKTENEGLKTENEGLKTENEG
Position: 70-96
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [55-70]
Chemical type: Peptide from protein
Sequence: LKTEKKEHEAENDKLK
Position: 97-112
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [55-70]
Chemical type: Peptide from protein
Sequence: LKTEKKEHEAENDKLK
Position: 97-112
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [55-70]
Chemical type: Peptide from protein
Sequence: LKTEKKEHEAENDKLK
Position: 97-112
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [55-70]
Chemical type: Peptide from protein
Sequence: LKTEKKEHEAENDKLK
Position: 97-112
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [55-70]
Chemical type: Peptide from protein
Sequence: LKTEKKEHEAENDKLK
Position: 97-112
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [61-90]
Chemical type: Peptide from protein
Sequence: EHEAENDKLKQQRDTLSTQKETLEREVQNT
Position: 103-132
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [61-90]
Chemical type: Peptide from protein
Sequence: EHEAENDKLKQQRDTLSTQKETLEREVQNT
Position: 103-132
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [61-90]
Chemical type: Peptide from protein
Sequence: EHEAENDKLKQQRDTLSTQKETLEREVQNT
Position: 103-132
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [70-102]
Chemical type: Peptide from protein
Sequence: KQQRDTLSTQKETLEREVQNTQYNNETLKIKNG
Position: 112-144
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [70-102]
Chemical type: Peptide from protein
Sequence: KQQRDTLSTQKETLEREVQNTQYNNETLKIKNG
Position: 112-144
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [70-102]
Chemical type: Peptide from protein
Sequence: KQQRDTLSTQKETLEREVQNTQYNNETLKIKNG
Position: 112-144
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [133-162]
Chemical type: Peptide from protein
Sequence: LEKTVKDKIAKEQENKETIGTLKKILDETV
Position: 175-204
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [133-162]
Chemical type: Peptide from protein
Sequence: LEKTVKDKIAKEQENKETIGTLKKILDETV
Position: 175-204
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [133-162]
Chemical type: Peptide from protein
Sequence: LEKTVKDKIAKEQENKETIGTLKKILDETV
Position: 175-204
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [133-162]
Chemical type: Peptide from protein
Sequence: LEKTVKDKIAKEQENKETIGTLKKILDETV
Position: 175-204
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [175-208]
Chemical type: Peptide from protein
Sequence: TIGTLKKILDETVKDKLAKEQKSKQNIGALKQEL
Position: 217-250
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [175-208]
Chemical type: Peptide from protein
Sequence: TIGTLKKILDETVKDKLAKEQKSKQNIGALKQEL
Position: 217-250
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [175-208]
Chemical type: Peptide from protein
Sequence: TIGTLKKILDETVKDKLAKEQKSKQNIGALKQEL
Position: 217-250
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [175-208]
Chemical type: Peptide from protein
Sequence: TIGTLKKILDETVKDKLAKEQKSKQNIGALKQEL
Position: 217-250
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [175-208]
Chemical type: Peptide from protein
Sequence: TIGTLKKILDETVKDKLAKEQKSKQNIGALKQEL
Position: 217-250
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [209-223]
Chemical type: Peptide from protein
Sequence: AKKQLEAEHQKLEEQNKISEASRK
Position: 277-300
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [209-223]
Chemical type: Peptide from protein
Sequence: AKKQLEAEHQKLEEQNKISEASRK
Position: 277-300
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [209-223]
Chemical type: Peptide from protein
Sequence: AKKQLEAEHQKLEEQNKISEASRK
Position: 277-300
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [209-223]
Chemical type: Peptide from protein
Sequence: AKKQLEAEHQKLEEQNKISEASRK
Position: 277-300
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [217-237]
Chemical type: Peptide from protein
Sequence: ISDASRKGLRRDLDASREAKK
Position: 259-279
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [217-237]
Chemical type: Peptide from protein
Sequence: ISDASRKGLRRDLDASREAKK
Position: 259-279
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [217-237]
Chemical type: Peptide from protein
Sequence: ISDASRKGLRRDLDASREAKK
Position: 259-279
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [217-237]
Chemical type: Peptide from protein
Sequence: ISDASRKGLRRDLDASREAKK
Position: 259-279
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [230-251]
Chemical type: Peptide from protein
Sequence: DASREAKKQLEAEHQKLEEQNK
Position: 272-293
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [230-251]
Chemical type: Peptide from protein
Sequence: DASREAKKQLEAEHQKLEEQNK
Position: 272-293
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [230-251]
Chemical type: Peptide from protein
Sequence: DASREAKKQLEAEHQKLEEQNK
Position: 272-293
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [300-319]
Chemical type: Peptide from protein
Sequence: DASREAKKQVEKALEEANSK
Position: 342-361
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [300-319]
Chemical type: Peptide from protein
Sequence: DASREAKKQVEKALEEANSK
Position: 342-361
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [300-319]
Chemical type: Peptide from protein
Sequence: DASREAKKQVEKALEEANSK
Position: 342-361
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [300-319]
Chemical type: Peptide from protein
Sequence: DASREAKKQVEKALEEANSK
Position: 342-361
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [300-319]
Chemical type: Peptide from protein
Sequence: DASREAKKQVEKALEEANSK
Position: 342-361
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [312-331]
Chemical type: Peptide from protein
Sequence: ALEEANSKLAALEKLNKELE
Position: 354-373
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [312-331]
Chemical type: Peptide from protein
Sequence: ALEEANSKLAALEKLNKELE
Position: 354-373
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [312-331]
Chemical type: Peptide from protein
Sequence: ALEEANSKLAALEKLNKELE
Position: 354-373
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [312-331]
Chemical type: Peptide from protein
Sequence: ALEEANSKLAALEKLNKELE
Position: 354-373
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [329-359]
Chemical type: Peptide from protein
Sequence: ELEESKKLTEKEKAELQAKLEAEAKALKEQL
Position: 371-401
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [329-359]
Chemical type: Peptide from protein
Sequence: ELEESKKLTEKEKAELQAKLEAEAKALKEQL
Position: 371-401
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [329-359]
Chemical type: Peptide from protein
Sequence: ELEESKKLTEKEKAELQAKLEAEAKALKEQL
Position: 371-401
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [329-359]
Chemical type: Peptide from protein
Sequence: ELEESKKLTEKEKAELQAKLEAEAKALKEQL
Position: 371-401
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [359-388]
Chemical type: Peptide from protein
Sequence: LAKQAEELAKLRAGKASDSQTPDTKPGNKA
Position: 401-430
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [359-388]
Chemical type: Peptide from protein
Sequence: LAKQAEELAKLRAGKASDSQTPDTKPGNKA
Position: 401-430
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [359-388]
Chemical type: Peptide from protein
Sequence: LAKQAEELAKLRAGKASDSQTPDTKPGNKA
Position: 401-430
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [359-388]
Chemical type: Peptide from protein
Sequence: LAKQAEELAKLRAGKASDSQTPDTKPGNKA
Position: 401-430
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [389-425]
Chemical type: Peptide from protein
Sequence: VPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANP
Position: 431-467
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [389-425]
Chemical type: Peptide from protein
Sequence: VPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANP
Position: 431-467
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [389-425]
Chemical type: Peptide from protein
Sequence: VPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANP
Position: 431-467
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: sM5 [389-425]
Chemical type: Peptide from protein
Sequence: VPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANP
Position: 431-467
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [426-450]
Chemical type: Peptide from protein
Sequence: FFTAAALTVMATAGVAAVVKRKEEN
Position: 468-492
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [426-450]
Chemical type: Peptide from protein
Sequence: FFTAAALTVMATAGVAAVVKRKEEN
Position: 468-492
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: sM5 [426-450]
Chemical type: Peptide from protein
Sequence: FFTAAALTVMATAGVAAVVKRKEEN
Position: 468-492
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Negative
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: M5 [21-27]
Chemical type: Peptide from protein
Sequence: ELENHDL
Position: 63-69
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: M5 [21-27]
Chemical type: Peptide from protein
Sequence: ELENHDL
Position: 63-69
Source molecule (GenBank): P02977.2
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone