Reference: So Jin Bing; Sune Justesen; Wells W Wu; Abdul Mohin Sajib; Stephanee Warrington; Alan Baer; Stephan Thorgrimsen; Rong-Fong Shen; Ronit Mazor. "Differential T cell immune responses to deamidated adeno-associated virus vector." Molecular therapy. Methods & clinical development (2022).

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Positive

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Positive

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Positive

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Positive

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Positive

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: MhcBinding
Result: Positive

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: MhcBinding
Result: Positive

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: MhcBinding
Result: Positive

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: MhcBinding
Result: Positive

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: MhcBinding
Result: Positive

Epitope: AAV8 N540D 20-mer
Chemical type: Peptide, no natural source
Sequence: KDDEERFFPSDGILIFGKQN
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Positive

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Positive

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative

Epitope: AAV8 N540iD 20-mer
Chemical type: Peptide from protein
Sequence: KDDEERFFPSNGILIFGKQN
Position: 530-549
Source molecule (GenBank): YP_077180.1
Assay category: MhcBinding
Result: Negative