Reference: Christine Jung; Christina Stoeckle; Karl-Heinz Wiesmüller; Rüdiger Laub; Frank Emmrich; Günther Jung; Arthur Melms. "Complementary strategies to elucidate T helper cell epitopes in myasthenia gravis." Journal of neuroimmunology (2008).

Epitope: AChR epsilon (1-15)
Chemical type: Peptide from protein
Sequence: KNEELRLYHHLFNNY
Position: 21-35
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (1-15)
Chemical type: Peptide from protein
Sequence: KNEELRLYHHLFNNY
Position: 21-35
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (1-15)
Chemical type: Peptide from protein
Sequence: KNEELRLYHHLFNNY
Position: 21-35
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (6-20)
Chemical type: Peptide from protein
Sequence: RLYHHLFNNYDPGSR
Position: 26-40
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (6-20)
Chemical type: Peptide from protein
Sequence: RLYHHLFNNYDPGSR
Position: 26-40
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (6-20)
Chemical type: Peptide from protein
Sequence: RLYHHLFNNYDPGSR
Position: 26-40
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (11-25)
Chemical type: Peptide from protein
Sequence: LFNNYDPGSRPVREP
Position: 31-45
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (11-25)
Chemical type: Peptide from protein
Sequence: LFNNYDPGSRPVREP
Position: 31-45
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (11-25)
Chemical type: Peptide from protein
Sequence: LFNNYDPGSRPVREP
Position: 31-45
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (21-35)
Chemical type: Peptide from protein
Sequence: PVREPEDTVTISLKV
Position: 41-55
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (21-35)
Chemical type: Peptide from protein
Sequence: PVREPEDTVTISLKV
Position: 41-55
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (21-35)
Chemical type: Peptide from protein
Sequence: PVREPEDTVTISLKV
Position: 41-55
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: AChR epsilon (26-40)
Chemical type: Peptide from protein
Sequence: EDTVTISLKVTLTNL
Position: 46-60
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (26-40)
Chemical type: Peptide from protein
Sequence: EDTVTISLKVTLTNL
Position: 46-60
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (26-40)
Chemical type: Peptide from protein
Sequence: EDTVTISLKVTLTNL
Position: 46-60
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: AChR epsilon (31-45)
Chemical type: Peptide from protein
Sequence: ISLKVTLTNLISLNE
Position: 51-65
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (31-45)
Chemical type: Peptide from protein
Sequence: ISLKVTLTNLISLNE
Position: 51-65
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (31-45)
Chemical type: Peptide from protein
Sequence: ISLKVTLTNLISLNE
Position: 51-65
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: AChR epsilon (36-50)
Chemical type: Peptide from protein
Sequence: TLTNLISLNEKEETL
Position: 56-70
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (36-50)
Chemical type: Peptide from protein
Sequence: TLTNLISLNEKEETL
Position: 56-70
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (36-50)
Chemical type: Peptide from protein
Sequence: TLTNLISLNEKEETL
Position: 56-70
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: AChR epsilon (41-55)
Chemical type: Peptide from protein
Sequence: ISLNEKEETLTTSVW
Position: 61-75
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (41-55)
Chemical type: Peptide from protein
Sequence: ISLNEKEETLTTSVW
Position: 61-75
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (41-55)
Chemical type: Peptide from protein
Sequence: ISLNEKEETLTTSVW
Position: 61-75
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: AChR epsilon (46-60)
Chemical type: Peptide from protein
Sequence: KEETLTTSVWIGIDW
Position: 66-80
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (46-60)
Chemical type: Peptide from protein
Sequence: KEETLTTSVWIGIDW
Position: 66-80
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (46-60)
Chemical type: Peptide from protein
Sequence: KEETLTTSVWIGIDW
Position: 66-80
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: AChR epsilon (51-65)
Chemical type: Peptide from protein
Sequence: TTSVWIGIDWQDYRL
Position: 71-85
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (51-65)
Chemical type: Peptide from protein
Sequence: TTSVWIGIDWQDYRL
Position: 71-85
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive-High
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (51-65)
Chemical type: Peptide from protein
Sequence: TTSVWIGIDWQDYRL
Position: 71-85
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-High

Epitope: AChR epsilon (61-75)
Chemical type: Peptide from protein
Sequence: QDYRLNYSKDDFGGI
Position: 81-95
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (61-75)
Chemical type: Peptide from protein
Sequence: QDYRLNYSKDDFGGI
Position: 81-95
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (61-75)
Chemical type: Peptide from protein
Sequence: QDYRLNYSKDDFGGI
Position: 81-95
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: AChR epsilon (66-80)
Chemical type: Peptide from protein
Sequence: NYSKDDFGGIETLRV
Position: 86-100
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (66-80)
Chemical type: Peptide from protein
Sequence: NYSKDDFGGIETLRV
Position: 86-100
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (66-80)
Chemical type: Peptide from protein
Sequence: NYSKDDFGGIETLRV
Position: 86-100
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (71-85)
Chemical type: Peptide from protein
Sequence: DFGGIETLRVPSELV
Position: 91-105
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (71-85)
Chemical type: Peptide from protein
Sequence: DFGGIETLRVPSELV
Position: 91-105
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (71-85)
Chemical type: Peptide from protein
Sequence: DFGGIETLRVPSELV
Position: 91-105
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (76-90)
Chemical type: Peptide from protein
Sequence: ETLRVPSELVWLPEI
Position: 96-110
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (76-90)
Chemical type: Peptide from protein
Sequence: ETLRVPSELVWLPEI
Position: 96-110
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (76-90)
Chemical type: Peptide from protein
Sequence: ETLRVPSELVWLPEI
Position: 96-110
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: AChR epsilon (81-95)
Chemical type: Peptide from protein
Sequence: PSELVWLPEIVLENN
Position: 101-115
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (81-95)
Chemical type: Peptide from protein
Sequence: PSELVWLPEIVLENN
Position: 101-115
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (81-95)
Chemical type: Peptide from protein
Sequence: PSELVWLPEIVLENN
Position: 101-115
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (86-100)
Chemical type: Peptide from protein
Sequence: WLPEIVLENNIDGQF
Position: 106-120
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (86-100)
Chemical type: Peptide from protein
Sequence: WLPEIVLENNIDGQF
Position: 106-120
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (86-100)
Chemical type: Peptide from protein
Sequence: WLPEIVLENNIDGQF
Position: 106-120
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (91-105)
Chemical type: Peptide from protein
Sequence: VLENNIDGQFGVAYD
Position: 111-125
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (91-105)
Chemical type: Peptide from protein
Sequence: VLENNIDGQFGVAYD
Position: 111-125
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (91-105)
Chemical type: Peptide from protein
Sequence: VLENNIDGQFGVAYD
Position: 111-125
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: AChR epsilon (101-115)
Chemical type: Peptide from protein
Sequence: GVAYDANVLVYEGGS
Position: 121-135
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (101-115)
Chemical type: Peptide from protein
Sequence: GVAYDANVLVYEGGS
Position: 121-135
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (101-115)
Chemical type: Peptide from protein
Sequence: GVAYDANVLVYEGGS
Position: 121-135
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-High

Epitope: AChR epsilon (106-120)
Chemical type: Peptide from protein
Sequence: ANVLVYEGGSVTWLP
Position: 126-140
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive-High
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (106-120)
Chemical type: Peptide from protein
Sequence: ANVLVYEGGSVTWLP
Position: 126-140
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (106-120)
Chemical type: Peptide from protein
Sequence: ANVLVYEGGSVTWLP
Position: 126-140
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: AChR epsilon (111-125)
Chemical type: Peptide from protein
Sequence: YEGGSVTWLPPAIYR
Position: 131-145
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (111-125)
Chemical type: Peptide from protein
Sequence: YEGGSVTWLPPAIYR
Position: 131-145
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (111-125)
Chemical type: Peptide from protein
Sequence: YEGGSVTWLPPAIYR
Position: 131-145
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (116-130)
Chemical type: Peptide from protein
Sequence: VTWLPPAIYRSVCAV
Position: 136-150
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (116-130)
Chemical type: Peptide from protein
Sequence: VTWLPPAIYRSVCAV
Position: 136-150
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (116-130)
Chemical type: Peptide from protein
Sequence: VTWLPPAIYRSVCAV
Position: 136-150
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: AChR epsilon (121-135)
Chemical type: Peptide from protein
Sequence: PAIYRSVCAVEVTYF
Position: 141-155
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (121-135)
Chemical type: Peptide from protein
Sequence: PAIYRSVCAVEVTYF
Position: 141-155
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (121-135)
Chemical type: Peptide from protein
Sequence: PAIYRSVCAVEVTYF
Position: 141-155
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: AChR epsilon (126-140)
Chemical type: Peptide from protein
Sequence: SVCAVEVTYFPFDWQ
Position: 146-160
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (126-140)
Chemical type: Peptide from protein
Sequence: SVCAVEVTYFPFDWQ
Position: 146-160
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (126-140)
Chemical type: Peptide from protein
Sequence: SVCAVEVTYFPFDWQ
Position: 146-160
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: AChR epsilon (131-145)
Chemical type: Peptide from protein
Sequence: EVTYFPFDWQNCSLI
Position: 151-165
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (131-145)
Chemical type: Peptide from protein
Sequence: EVTYFPFDWQNCSLI
Position: 151-165
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (131-145)
Chemical type: Peptide from protein
Sequence: EVTYFPFDWQNCSLI
Position: 151-165
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (136-150)
Chemical type: Peptide from protein
Sequence: PFDWQNCSLIFRSQT
Position: 156-170
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (136-150)
Chemical type: Peptide from protein
Sequence: PFDWQNCSLIFRSQT
Position: 156-170
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (136-150)
Chemical type: Peptide from protein
Sequence: PFDWQNCSLIFRSQT
Position: 156-170
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (141-155)
Chemical type: Peptide from protein
Sequence: NCSLIFRSQTYNAEE
Position: 161-175
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (141-155)
Chemical type: Peptide from protein
Sequence: NCSLIFRSQTYNAEE
Position: 161-175
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (141-155)
Chemical type: Peptide from protein
Sequence: NCSLIFRSQTYNAEE
Position: 161-175
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (146-160)
Chemical type: Peptide from protein
Sequence: FRSQTYNAEEVEFTF
Position: 166-180
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (146-160)
Chemical type: Peptide from protein
Sequence: FRSQTYNAEEVEFTF
Position: 166-180
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (146-160)
Chemical type: Peptide from protein
Sequence: FRSQTYNAEEVEFTF
Position: 166-180
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (156-170)
Chemical type: Peptide from protein
Sequence: VEFTFAVDNDGKTIN
Position: 176-190
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (156-170)
Chemical type: Peptide from protein
Sequence: VEFTFAVDNDGKTIN
Position: 176-190
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (156-170)
Chemical type: Peptide from protein
Sequence: VEFTFAVDNDGKTIN
Position: 176-190
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (171-185)
Chemical type: Peptide from protein
Sequence: KIDIDTEAYTENGEW
Position: 191-205
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (171-185)
Chemical type: Peptide from protein
Sequence: KIDIDTEAYTENGEW
Position: 191-205
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (171-185)
Chemical type: Peptide from protein
Sequence: KIDIDTEAYTENGEW
Position: 191-205
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (176-190)
Chemical type: Peptide from protein
Sequence: TEAYTENGEWAIDFC
Position: 196-210
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (176-190)
Chemical type: Peptide from protein
Sequence: TEAYTENGEWAIDFC
Position: 196-210
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (176-190)
Chemical type: Peptide from protein
Sequence: TEAYTENGEWAIDFC
Position: 196-210
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: AChR epsilon (181-195)
Chemical type: Peptide from protein
Sequence: ENGEWAIDFCPGVIR
Position: 201-215
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (181-195)
Chemical type: Peptide from protein
Sequence: ENGEWAIDFCPGVIR
Position: 201-215
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (181-195)
Chemical type: Peptide from protein
Sequence: ENGEWAIDFCPGVIR
Position: 201-215
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: AChR epsilon (186-200)
Chemical type: Peptide from protein
Sequence: AIDFCPGVIRRHHGG
Position: 206-220
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (186-200)
Chemical type: Peptide from protein
Sequence: AIDFCPGVIRRHHGG
Position: 206-220
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (186-200)
Chemical type: Peptide from protein
Sequence: AIDFCPGVIRRHHGG
Position: 206-220
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (191-205)
Chemical type: Peptide from protein
Sequence: PGVIRRHHGGATDGP
Position: 211-225
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (191-205)
Chemical type: Peptide from protein
Sequence: PGVIRRHHGGATDGP
Position: 211-225
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (191-205)
Chemical type: Peptide from protein
Sequence: PGVIRRHHGGATDGP
Position: 211-225
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (201-215)
Chemical type: Peptide from protein
Sequence: ATDGPGETDVIYSLI
Position: 221-235
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (201-215)
Chemical type: Peptide from protein
Sequence: ATDGPGETDVIYSLI
Position: 221-235
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (201-215)
Chemical type: Peptide from protein
Sequence: ATDGPGETDVIYSLI
Position: 221-235
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (196-210)
Chemical type: Peptide from protein
Sequence: RHHGGATDGPGETDV
Position: 216-230
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (196-210)
Chemical type: Peptide from protein
Sequence: RHHGGATDGPGETDV
Position: 216-230
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (196-210)
Chemical type: Peptide from protein
Sequence: RHHGGATDGPGETDV
Position: 216-230
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (206-220)
Chemical type: Peptide from protein
Sequence: GETDVIYSLIIRRKP
Position: 226-240
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (206-220)
Chemical type: Peptide from protein
Sequence: GETDVIYSLIIRRKP
Position: 226-240
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (206-220)
Chemical type: Peptide from protein
Sequence: GETDVIYSLIIRRKP
Position: 226-240
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-High

Epitope: AChR epsilon (211-225)
Chemical type: Peptide from protein
Sequence: IYSLIIRRKPLFYVI
Position: 231-245
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (211-225)
Chemical type: Peptide from protein
Sequence: IYSLIIRRKPLFYVI
Position: 231-245
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (211-225)
Chemical type: Peptide from protein
Sequence: IYSLIIRRKPLFYVI
Position: 231-245
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-High

Epitope: AChR epsilon (216-230)
Chemical type: Peptide from protein
Sequence: IRRKPLFYVINIIVP
Position: 236-250
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (216-230)
Chemical type: Peptide from protein
Sequence: IRRKPLFYVINIIVP
Position: 236-250
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive-High
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (216-230)
Chemical type: Peptide from protein
Sequence: IRRKPLFYVINIIVP
Position: 236-250
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Low