Reference: Katherine Cook; Wei Xue; Suha Atabani; Peter Symonds; Abdullah Al Omari; Ian Daniels; Sabaria Shah; Ruhul Hasan Choudhury; Daisy Weston; Rachael Metheringham; Victoria Brentville; Lindy Durrant. "Vaccine Can Induce CD4-Mediated Responses to Homocitrullinated Peptides  Multiple HLA-Types and Confer Anti-Tumor Immunity." Frontiers in immunology (2022).

Epitope: Aldo 140-157 (Hcit)
Chemical type: Peptide from protein
Sequence: DGADFAKWRCVLKIGEH
Position: 141-157
Source molecule (GenBank): P04075.2
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Aldo 140-157 (Hcit)
Chemical type: Peptide from protein
Sequence: DGADFAKWRCVLKIGEH
Position: 141-157
Source molecule (GenBank): P04075.2
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Aldo 140-157 (Hcit)
Chemical type: Peptide from protein
Sequence: DGADFAKWRCVLKIGEH
Position: 141-157
Source molecule (GenBank): P04075.2
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: Aldo 140-157 (Hcit)
Chemical type: Peptide from protein
Sequence: DGADFAKWRCVLKIGEH
Position: 141-157
Source molecule (GenBank): P04075.2
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 101-120 (Hcit)
Chemical type: Peptide from protein
Sequence: KFASFIDKVRFLEQQNKMLE
Position: 101-120
Source molecule (GenBank): P05787.7
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 101-120 (Hcit)
Chemical type: Peptide from protein
Sequence: KFASFIDKVRFLEQQNKMLE
Position: 101-120
Source molecule (GenBank): P05787.7
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 112-131 (Hcit)
Chemical type: Peptide from protein
Sequence: LEQQNKMLETKWSLLQQQKT
Position: 112-131
Source molecule (GenBank): P05787.7
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 112-131 (Hcit)
Chemical type: Peptide from protein
Sequence: LEQQNKMLETKWSLLQQQKT
Position: 112-131
Source molecule (GenBank): P05787.7
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 112-131 (Hcit)
Chemical type: Peptide from protein
Sequence: LEQQNKMLETKWSLLQQQKT
Position: 112-131
Source molecule (GenBank): P05787.7
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 182-202 (Hcit)
Chemical type: Peptide from protein
Sequence: EINKRTEMENEFVLIKKDVDE
Position: 182-202
Source molecule (GenBank): P05787.7
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 371-388 (Hcit)
Chemical type: Peptide from protein
Sequence: LREYQELMNVKLALDIEI
Position: 371-388
Source molecule (GenBank): P05787.7
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 371-388 (Hcit)
Chemical type: Peptide from protein
Sequence: LREYQELMNVKLALDIEI
Position: 371-388
Source molecule (GenBank): P05787.7
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: Cyk8 371-388 (Hcit)
Chemical type: Peptide from protein
Sequence: LREYQELMNVKLALDIEI
Position: 371-388
Source molecule (GenBank): P05787.7
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 371-388 (Hcit)
Chemical type: Peptide from protein
Sequence: LREYQELMNVKLALDIEI
Position: 371-388
Source molecule (GenBank): P05787.7
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 371-388 (Hcit)
Chemical type: Peptide from protein
Sequence: LREYQELMNVKLALDIEI
Position: 371-388
Source molecule (GenBank): P05787.7
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 381-399 (Hcit)
Chemical type: Peptide from protein
Sequence: KLALDIEIATYRKLLEGEE
Position: 381-399
Source molecule (GenBank): P05787.7
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 116-135 (Hcit)
Chemical type: Peptide from protein
Sequence: NYIDKVRFLEQQNKILLAEL
Position: 116-135
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: Vim 116-135 (Hcit)
Chemical type: Peptide from protein
Sequence: NYIDKVRFLEQQNKILLAEL
Position: 116-135
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: Vim 116-135 (Hcit)
Chemical type: Peptide from protein
Sequence: NYIDKVRFLEQQNKILLAEL
Position: 116-135
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 116-135 (Hcit)
Chemical type: Peptide from protein
Sequence: NYIDKVRFLEQQNKILLAEL
Position: 116-135
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Vim 116-135 (Hcit)
Chemical type: Peptide from protein
Sequence: NYIDKVRFLEQQNKILLAEL
Position: 116-135
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Vim 116-135 (Hcit)
Chemical type: Peptide from protein
Sequence: NYIDKVRFLEQQNKILLAEL
Position: 116-135
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Vim 116-135 (Hcit)
Chemical type: Peptide from protein
Sequence: NYIDKVRFLEQQNKILLAEL
Position: 116-135
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: Vim 116-135 (Hcit)
Chemical type: Peptide from protein
Sequence: NYIDKVRFLEQQNKILLAEL
Position: 116-135
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 116-135 (Hcit)
Chemical type: Peptide from protein
Sequence: NYIDKVRFLEQQNKILLAEL
Position: 116-135
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 116-135 (Hcit)
Chemical type: Peptide from protein
Sequence: NYIDKVRFLEQQNKILLAEL
Position: 116-135
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 116-135 (Hcit)
Chemical type: Peptide from protein
Sequence: NYIDKVRFLEQQNKILLAEL
Position: 116-135
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 215-235 (Hcit)
Chemical type: Peptide from protein
Sequence: LARLDLERKVESLQEEIAFLK
Position: 215-235
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 215-235 (Hcit)
Chemical type: Peptide from protein
Sequence: LARLDLERKVESLQEEIAFLK
Position: 215-235
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 255-275 (Hcit)
Chemical type: Peptide from protein
Sequence: QIDVDVSKPDLTAALRDVRQQ
Position: 255-275
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 255-275 (Hcit)
Chemical type: Peptide from protein
Sequence: QIDVDVSKPDLTAALRDVRQQ
Position: 255-275
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 286-303 (Hcit)
Chemical type: Peptide from protein
Sequence: EAEEWYKSKFADLSEAAN
Position: 286-303
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 286-303 (Hcit)
Chemical type: Peptide from protein
Sequence: EAEEWYKSKFADLSEAAN
Position: 286-303
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 431-460 (Hcit)
Chemical type: Peptide from protein
Sequence: LPLVDTHSKRTLLIKTVETRDGQV
Position: 431-454
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 431-460 (Hcit)
Chemical type: Peptide from protein
Sequence: LPLVDTHSKRTLLIKTVETRDGQV
Position: 431-454
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Aldo 74-93
Chemical type: Peptide from protein
Sequence: IGGVILFHETLYQKADDGRP
Position: 74-93
Source molecule (GenBank): P04075.2
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Aldo 74-93
Chemical type: Peptide from protein
Sequence: IGGVILFHETLYQKADDGRP
Position: 74-93
Source molecule (GenBank): P04075.2
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Aldo 140-157
Chemical type: Peptide from protein
Sequence: DGADFAKWRCVLKIGEH
Position: 141-157
Source molecule (GenBank): P04075.2
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 120-134 (Hcit)
Chemical type: Peptide from protein
Sequence: KVRFLEQQNKILLAE
Position: 120-134
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 120-134 (Hcit)
Chemical type: Peptide from protein
Sequence: KVRFLEQQNKILLAE
Position: 120-134
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Vim 120-134 (Hcit)
Chemical type: Peptide from protein
Sequence: KVRFLEQQNKILLAE
Position: 120-134
Source molecule (GenBank): P08670.4
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 371-388
Chemical type: Peptide from protein
Sequence: LREYQELMNVKLALDIEI
Position: 371-388
Source molecule (GenBank): P05787.7
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Cyk8 371-388
Chemical type: Peptide from protein
Sequence: LREYQELMNVKLALDIEI
Position: 371-388
Source molecule (GenBank): P05787.7
Assay category: TCell
Result: Negative
Host:  8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo