Reference: Kathleen P Pratt; Jiahua Qian; Ekram Ellaban; David K Okita; Brenda M Diethelm-Okita; Bianca Conti-Fine; David W Scott. "Immunodominant T-cell epitopes in the factor VIII C2 domain are located within an inhibitory antibody binding site." Thrombosis and haemostasis (2004).

Epitope: C2-2
Chemical type: Peptide from protein
Sequence: ESKAISDAQITASSYFTNMF
Position: 2200-2219
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-2
Chemical type: Peptide from protein
Sequence: ESKAISDAQITASSYFTNMF
Position: 2200-2219
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-3
Chemical type: Peptide from protein
Sequence: TASSYFTNMFATWSPSKARL
Position: 2210-2229
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: C2-3
Chemical type: Peptide from protein
Sequence: TASSYFTNMFATWSPSKARL
Position: 2210-2229
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-3
Chemical type: Peptide from protein
Sequence: TASSYFTNMFATWSPSKARL
Position: 2210-2229
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Short Term Restimulated

Epitope: C2-3
Chemical type: Peptide from protein
Sequence: TASSYFTNMFATWSPSKARL
Position: 2210-2229
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-4
Chemical type: Peptide from protein
Sequence: ATWSPSKARLHLQGRSNAWR
Position: 2220-2239
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-4
Chemical type: Peptide from protein
Sequence: ATWSPSKARLHLQGRSNAWR
Position: 2220-2239
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-5
Chemical type: Peptide from protein
Sequence: HLQGRSNAWRPQVNNPKEWL
Position: 2230-2249
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-5
Chemical type: Peptide from protein
Sequence: HLQGRSNAWRPQVNNPKEWL
Position: 2230-2249
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-6
Chemical type: Peptide from protein
Sequence: PQVNNPKEWLQVDFQKTMKV
Position: 2240-2259
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-6
Chemical type: Peptide from protein
Sequence: PQVNNPKEWLQVDFQKTMKV
Position: 2240-2259
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-7
Chemical type: Peptide from protein
Sequence: QVDFQKTMKVTGVTTQGVKS
Position: 2250-2269
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-7
Chemical type: Peptide from protein
Sequence: QVDFQKTMKVTGVTTQGVKS
Position: 2250-2269
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-8
Chemical type: Peptide from protein
Sequence: TGVTTQGVKSLLTSMYVKEF
Position: 2260-2279
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-8
Chemical type: Peptide from protein
Sequence: TGVTTQGVKSLLTSMYVKEF
Position: 2260-2279
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-9
Chemical type: Peptide from protein
Sequence: LLTSMYVKEFLISSSQDGHQ
Position: 2270-2289
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-9
Chemical type: Peptide from protein
Sequence: LLTSMYVKEFLISSSQDGHQ
Position: 2270-2289
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-10
Chemical type: Peptide from protein
Sequence: LISSSQDGHQWTLFFQNGKV
Position: 2280-2299
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-10
Chemical type: Peptide from protein
Sequence: LISSSQDGHQWTLFFQNGKV
Position: 2280-2299
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-11
Chemical type: Peptide from protein
Sequence: WTLFFQNGKVKVFQGNQDSF
Position: 2290-2309
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-11
Chemical type: Peptide from protein
Sequence: WTLFFQNGKVKVFQGNQDSF
Position: 2290-2309
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-12
Chemical type: Peptide from protein
Sequence: KVFQGNQDSFTPVVNSLDPP
Position: 2300-2319
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-12
Chemical type: Peptide from protein
Sequence: KVFQGNQDSFTPVVNSLDPP
Position: 2300-2319
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-13
Chemical type: Peptide from protein
Sequence: TPVVNSLDPPLLTRYLRIHP
Position: 2310-2329
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-13
Chemical type: Peptide from protein
Sequence: TPVVNSLDPPLLTRYLRIHP
Position: 2310-2329
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-14
Chemical type: Peptide from protein
Sequence: LLTRYLRIHPQSWVHQIALR
Position: 2320-2339
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-14
Chemical type: Peptide from protein
Sequence: LLTRYLRIHPQSWVHQIALR
Position: 2320-2339
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-15
Chemical type: Peptide from protein
Sequence: QSWVHQIALRMEVLGCEAQD
Position: 2330-2349
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-15
Chemical type: Peptide from protein
Sequence: QSWVHQIALRMEVLGCEAQD
Position: 2330-2349
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-16
Chemical type: Peptide from protein
Sequence: MEVLGCEAQDLY
Position: 2340-2351
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-16
Chemical type: Peptide from protein
Sequence: MEVLGCEAQDLY
Position: 2340-2351
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo