Reference: Grace E Mantus; Ankita J Chopde; Jason Gorman; Lauren Y Cominsky; Amine Ourahmane; Adrian Creanga; Geoffrey D Shimberg; Rebecca A Gillespie; David J Van Wazer; Tongqing Zhou; Suprabhath R Gajjala; Connor Williams; Emma Maestle; Douglas S Reed; Leonid Serebryannyy; Pamela Costner; Lasonji Holman; Joseph P Casazza; Richard A Koup; Lesia K Dropulic; Peter D Kwong; Adrian B McDermott; Masaru Kanekiyo; Sarah F Andrews. "Vaccination with different group 2 influenza subtypes alters epitope targeting and breadth of hemagglutinin stem-specific human B cells." Science translational medicine (2025).

Epitope: Epitope of Fab c115.131 on H10 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: G341, L342, F343, G344, E355, G356, V358, D359, R365, G371, T372, G373, Q374
Source molecule (GenBank): AHK10761.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab c115.131 on H10 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: G341, L342, F343, G344, E355, G356, V358, D359, R365, G371, T372, G373, Q374
Source molecule (GenBank): AHK10761.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab c968.180 on H10 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L342, I346, D359, R365, N368, A369, Q370, G371, T372, G373, Q374
Source molecule (GenBank): AHK10761.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab c968.180 on H10 HA trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: L342, I346, D359, R365, N368, A369, Q370, G371, T372, G373, Q374
Source molecule (GenBank): AHK10761.1
Assay category: BCell
Result: Positive

Epitope: Q34
Chemical type: Discontinuous protein residues
Discontinuous residues: Q374
Source molecule (GenBank): AHK10761.1
Assay category: BCell
Result: Positive

Epitope: Q34
Chemical type: Discontinuous protein residues
Discontinuous residues: Q374
Source molecule (GenBank): AHK10761.1
Assay category: BCell
Result: Positive

Epitope: I45
Chemical type: Discontinuous protein residues
Discontinuous residues: I385
Source molecule (GenBank): AHK10761.1
Assay category: BCell
Result: Positive

Epitope: I45
Chemical type: Discontinuous protein residues
Discontinuous residues: I385
Source molecule (GenBank): AHK10761.1
Assay category: BCell
Result: Positive

Epitope: I45
Chemical type: Discontinuous protein residues
Discontinuous residues: I385
Source molecule (GenBank): AHK10761.1
Assay category: BCell
Result: Positive-Low

Epitope: I45
Chemical type: Discontinuous protein residues
Discontinuous residues: I385
Source molecule (GenBank): AHK10761.1
Assay category: BCell
Result: Positive

Epitope: Q34
Chemical type: Discontinuous protein residues
Discontinuous residues: Q379
Source molecule (GenBank): AIU46082.1
Assay category: BCell
Result: Positive
Host:  18-50 years

Epitope: I45
Chemical type: Discontinuous protein residues
Discontinuous residues: I390
Source molecule (GenBank): AIU46082.1
Assay category: BCell
Result: Negative
Host:  18-50 years

Epitope: T34
Chemical type: Discontinuous protein residues
Discontinuous residues: T373
Source molecule (GenBank): YP_009118475.1
Assay category: BCell
Result: Positive

Epitope: I45
Chemical type: Discontinuous protein residues
Discontinuous residues: I384
Source molecule (GenBank): YP_009118475.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb CR8020 on H3 HA
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E341; B: E360, G361, I363, D364, R370, E375, T377, G378, Q379, A380, A381, L383, N491, E495
Source molecule (GenBank): Q91MA7.1
Assay category: BCell
Result: Positive

Epitope: Epitope of mAb CR8020 on H3 HA
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E341; B: E360, G361, I363, D364, R370, E375, T377, G378, Q379, A380, A381, L383, N491, E495
Source molecule (GenBank): Q91MA7.1
Assay category: BCell
Result: Positive-Low