Reference: Thomas Marti; Oyvind Molberg; Qing Li; Gary M Gray; Chaitan Khosla; Ludvig M Sollid. "Prolyl endopeptidase-mediated destruction of T cell epitopes in whole gluten: chemical and immunological characterization." The Journal of pharmacology and experimental therapeutics (2005).

Epitope: α-I (Var1) core
Chemical type: Peptide from protein
Sequence: PFPQPQLPY
Position: 80-88
Source molecule (GenBank): P18573.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: gastrointestinal tract
Culture conditions: Cell Line / Clone

Epitope: α-II core
Chemical type: Peptide from protein
Sequence: PQPQLPYPQ
Position: 82-90
Source molecule (GenBank): P18573.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: gastrointestinal tract
Culture conditions: Cell Line / Clone

Epitope: α-III (Var2 of α-I) core
Chemical type: Peptide from protein
Sequence: PYPQPQLPY
Position: 87-95
Source molecule (GenBank): P18573.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: gastrointestinal tract
Culture conditions: Cell Line / Clone

Epitope: γ-I core
Chemical type: Peptide from protein
Sequence: PQQSFPQQQ
Position: 161-169
Source molecule (GenBank): P08453.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: gastrointestinal tract
Culture conditions: Cell Line / Clone

Epitope: γ-II (Glia-γ30) core
Chemical type: Peptide from protein
Sequence: IQPQQPAQL
Position: 279-287
Source molecule (GenBank): P08453.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: gastrointestinal tract
Culture conditions: Cell Line / Clone

Epitope: γ-III core
Chemical type: Peptide from protein
Sequence: QQPQQPYPQ
Position: 86-94
Source molecule (GenBank): P08079.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: gastrointestinal tract
Culture conditions: Cell Line / Clone

Epitope: γ-IV core
Chemical type: Peptide from protein
Sequence: SQPQQQFPQ
Position: 121-129
Source molecule (GenBank): P08079.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: gastrointestinal tract
Culture conditions: Cell Line / Clone

Epitope: γ-VI core
Chemical type: Peptide from protein
Sequence: QQPFPQQPQ
Position: 63-71
Source molecule (GenBank): Q8L6B2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: gastrointestinal tract
Culture conditions: Cell Line / Clone

Epitope: αG-33
Chemical type: Peptide from protein
Sequence: LQLQPFPQPQLPYPQPQLPYPQPQLPYPQPQPF
Position: 76-108
Source molecule (GenBank): P18573.1
Assay category: TCell
Result: Positive-High
Cell type: T cell
Tissue: gastrointestinal tract
Culture conditions: Cell Line / Clone

Epitope: α-I
Chemical type: Peptide from protein
Sequence: QLQPFPQPQLPY
Position: 77-88
Source molecule (GenBank): P18573.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: gastrointestinal tract
Culture conditions: Cell Line / Clone

Epitope: α-II
Chemical type: Peptide from protein
Sequence: PQPQLPYPQPQLPY
Position: 82-95
Source molecule (GenBank): P18573.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: gastrointestinal tract
Culture conditions: Cell Line / Clone

Epitope: γ-II
Chemical type: Peptide from protein
Sequence: GIIQPQQPAQL
Position: 277-287
Source molecule (GenBank): P08453.1
Assay category: TCell
Result: Positive-High
Cell type: T cell
Tissue: gastrointestinal tract
Culture conditions: Cell Line / Clone

Epitope: γ-III and γ-VI
Chemical type: Peptide from protein
Sequence: LQPQQPFPQQPQQPYPQQPQ
Position: 60-79
Source molecule (GenBank): Q8L6B2.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: gastrointestinal tract
Culture conditions: Cell Line / Clone

Epitope: Glu-5
Chemical type: Peptide, no natural source
Sequence: QQXSQPQXPQQQQXPQQPQQF
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: gastrointestinal tract
Culture conditions: Cell Line / Clone