Reference: Cailin Yu; Jeremy C Burns; William H Robinson; Paul J Utz; Peggy P Ho; Lawrence Steinman; Alan B Frey. "Identification of Candidate Tolerogenic CD8(+) T Cell Epitopes for Therapy of Type 1 Diabetes in the NOD Mouse Model." Journal of diabetes research (2016).

Epitope: Ins 39-47
Chemical type: Peptide, no natural source
Sequence: LYLVCGERV
Assay category: TCell
Result: Positive
Host: F 3-32 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Ins 39-47
Chemical type: Peptide, no natural source
Sequence: LYLVCGERV
Assay category: TCell
Result: Positive-Low
Host: F 4 weeks

Epitope: Ins 39-47
Chemical type: Peptide, no natural source
Sequence: LYLVCGERV
Assay category: TCell
Result: Positive
Host: F 3-32 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Ins 39-47
Chemical type: Peptide, no natural source
Sequence: LYLVCGERV
Assay category: TCell
Result: Positive
Host: F 3-32 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Ins 39-47
Chemical type: Peptide, no natural source
Sequence: LYLVCGERV
Assay category: MhcBinding
Result: Positive

Epitope: DbetaH 233-241
Chemical type: Peptide from protein
Sequence: TYWCYITEL
Position: 233-241
Source molecule (GenBank): AAB24330.1
Assay category: TCell
Result: Positive
Host: F 3-32 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: DbetaH 233-241
Chemical type: Peptide from protein
Sequence: TYWCYITEL
Position: 233-241
Source molecule (GenBank): AAB24330.1
Assay category: TCell
Result: Positive
Host: F 3-32 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: DbetaH 233-241
Chemical type: Peptide from protein
Sequence: TYWCYITEL
Position: 233-241
Source molecule (GenBank): AAB24330.1
Assay category: TCell
Result: Positive
Host: F 4 weeks

Epitope: DbetaH 233-241
Chemical type: Peptide from protein
Sequence: TYWCYITEL
Position: 233-241
Source molecule (GenBank): AAB24330.1
Assay category: TCell
Result: Positive
Host: F 3-32 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: DbetaH 233-241
Chemical type: Peptide from protein
Sequence: TYWCYITEL
Position: 233-241
Source molecule (GenBank): AAB24330.1
Assay category: MhcBinding
Result: Positive

Epitope: ZnT8 158-166
Chemical type: Peptide from protein
Sequence: LYLACERLL
Position: 158-166
Source molecule (GenBank): NP_766404.1
Assay category: TCell
Result: Positive
Host: F 3-32 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: ZnT8 158-166
Chemical type: Peptide from protein
Sequence: LYLACERLL
Position: 158-166
Source molecule (GenBank): NP_766404.1
Assay category: TCell
Result: Negative
Host: F 3-32 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: ZnT8 158-166
Chemical type: Peptide from protein
Sequence: LYLACERLL
Position: 158-166
Source molecule (GenBank): NP_766404.1
Assay category: TCell
Result: Positive
Host: F 3-32 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: ZnT8 158-166
Chemical type: Peptide from protein
Sequence: LYLACERLL
Position: 158-166
Source molecule (GenBank): NP_766404.1
Assay category: TCell
Result: Negative
Host: F 4 weeks

Epitope: ZnT8 158-166
Chemical type: Peptide from protein
Sequence: LYLACERLL
Position: 158-166
Source molecule (GenBank): NP_766404.1
Assay category: MhcBinding
Result: Positive

Epitope: IGRP 206-214
Chemical type: Peptide from protein
Sequence: VYLKTNVFL
Position: 206-214
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Negative
Host: F

Epitope: IGRP 206-214
Chemical type: Peptide from protein
Sequence: VYLKTNVFL
Position: 206-214
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Positive
Host: F 3-32 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: IGRP 206-214
Chemical type: Peptide from protein
Sequence: VYLKTNVFL
Position: 206-214
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Positive
Host: F 3-32 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: IGRP 206-214
Chemical type: Peptide from protein
Sequence: VYLKTNVFL
Position: 206-214
Source molecule (GenBank): NP_067306.1
Assay category: TCell
Result: Positive
Host: F 3-32 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: IGRP 206-214
Chemical type: Peptide from protein
Sequence: VYLKTNVFL
Position: 206-214
Source molecule (GenBank): NP_067306.1
Assay category: MhcBinding
Result: Positive

Epitope: GAD65 178-186
Chemical type: Peptide from protein
Sequence: YFNQLSTGL
Position: 178-186
Source molecule (GenBank): BAA22893.1
Assay category: TCell
Result: Positive
Host: F 3-32 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: GAD65 178-186
Chemical type: Peptide from protein
Sequence: YFNQLSTGL
Position: 178-186
Source molecule (GenBank): BAA22893.1
Assay category: TCell
Result: Negative
Host: F 3-32 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: GAD65 178-186
Chemical type: Peptide from protein
Sequence: YFNQLSTGL
Position: 178-186
Source molecule (GenBank): BAA22893.1
Assay category: TCell
Result: Positive-Low
Host: F 3-32 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GAD65 178-186
Chemical type: Peptide from protein
Sequence: YFNQLSTGL
Position: 178-186
Source molecule (GenBank): BAA22893.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: ICAp69 78-86
Chemical type: Peptide from protein
Sequence: LYQKRICFL
Position: 78-86
Source molecule (GenBank): AAC52992.1
Assay category: TCell
Result: Negative
Host: F 3-32 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: ICAp69 78-86
Chemical type: Peptide from protein
Sequence: LYQKRICFL
Position: 78-86
Source molecule (GenBank): AAC52992.1
Assay category: TCell
Result: Negative
Host: F 3-32 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: ICAp69 78-86
Chemical type: Peptide from protein
Sequence: LYQKRICFL
Position: 78-86
Source molecule (GenBank): AAC52992.1
Assay category: TCell
Result: Positive
Host: F 3-32 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: ICAp69 78-86
Chemical type: Peptide from protein
Sequence: LYQKRICFL
Position: 78-86
Source molecule (GenBank): AAC52992.1
Assay category: MhcBinding
Result: Positive