Reference: Jinsheng Wen; Annie Elong Ngono; Jose Angel Regla-Nava; Kenneth Kim; Matthew J Gorman; Michael S Diamond; Sujan Shresta. "Dengue virus-reactive CD8<sup>+</sup> T cells mediate cross-protection against subsequent Zika virus challenge." Nature communications (2017).

Epitope: MR-prM (20-28)
Chemical type: Peptide from protein
Sequence: ISFATTLGV
Position: 145-153
Source molecule (GenBank): AHL43501.1
Assay category: TCell
Result: Negative
MHC allele types: 167
Host:  5-6 weeks

Epitope: MR-prM (20-28)
Chemical type: Peptide from protein
Sequence: ISFATTLGV
Position: 145-153
Source molecule (GenBank): AHL43501.1
Assay category: TCell
Result: Positive
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MR-prM (20-28)
Chemical type: Peptide from protein
Sequence: ISFATTLGV
Position: 145-153
Source molecule (GenBank): AHL43501.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-prM (44-52)
Chemical type: Peptide from protein
Sequence: ATMSYECPM
Position: 169-177
Source molecule (GenBank): AEN75265.1
Assay category: TCell
Result: Positive
MHC allele types: 167
Host:  5-6 weeks

Epitope: FSS/MR-prM (44-52)
Chemical type: Peptide from protein
Sequence: ATMSYECPM
Position: 169-177
Source molecule (GenBank): AEN75265.1
Assay category: TCell
Result: Positive
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-prM (44-52)
Chemical type: Peptide from protein
Sequence: ATMSYECPM
Position: 169-177
Source molecule (GenBank): AEN75265.1
Assay category: TCell
Result: Positive
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-E (4-12)
Chemical type: Peptide from protein
Sequence: IGVSNRDFV
Position: 4-12
Source molecule (GenBank): AIC06934.1
Assay category: TCell
Result: Positive
MHC allele types: 167
Host:  5-6 weeks

Epitope: FSS/MR-E (4-12)
Chemical type: Peptide from protein
Sequence: IGVSNRDFV
Position: 4-12
Source molecule (GenBank): AIC06934.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS3 (347-355)
Chemical type: Peptide from protein
Sequence: PSVRNGNEI
Position: 364-372
Source molecule (GenBank): YP_009227202.1
Assay category: TCell
Result: Positive
MHC allele types: 167
Host:  5-6 weeks

Epitope: FSS/MR-NS3 (347-355)
Chemical type: Peptide from protein
Sequence: PSVRNGNEI
Position: 364-372
Source molecule (GenBank): YP_009227202.1
Assay category: TCell
Result: Positive
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS3 (347-355)
Chemical type: Peptide from protein
Sequence: PSVRNGNEI
Position: 364-372
Source molecule (GenBank): YP_009227202.1
Assay category: TCell
Result: Positive
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS5 (18-27)
Chemical type: Peptide from protein
Sequence: CAEAPNMKII
Position: 2789-2798
Source molecule (GenBank): AMD61711.1
Assay category: TCell
Result: Positive
MHC allele types: 167
Host:  5-6 weeks

Epitope: FSS/MR-NS5 (18-27)
Chemical type: Peptide from protein
Sequence: CAEAPNMKII
Position: 2789-2798
Source molecule (GenBank): AMD61711.1
Assay category: TCell
Result: Positive
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS5 (18-27)
Chemical type: Peptide from protein
Sequence: CAEAPNMKII
Position: 2789-2798
Source molecule (GenBank): AMD61711.1
Assay category: TCell
Result: Positive
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: DENV2-prM (44-52)
Chemical type: Peptide from protein
Sequence: DTITYKCPL
Position: 161-169
Source molecule (GenBank): AAA73185.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: DENV2-prM (44-52)
Chemical type: Peptide from protein
Sequence: DTITYKCPL
Position: 161-169
Source molecule (GenBank): AAA73185.1
Assay category: TCell
Result: Positive
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: DENV2-E (4-12)
Chemical type: Peptide from protein
Sequence: IGISNRDFV
Position: 4-12
Source molecule (GenBank): AJP06038.1
Assay category: TCell
Result: Positive
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: DENV2-E (4-12)
Chemical type: Peptide from protein
Sequence: IGISNRDFV
Position: 4-12
Source molecule (GenBank): AJP06038.1
Assay category: TCell
Result: Positive
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: DENV2-NS3 (347-355)
Chemical type: Peptide from protein
Sequence: PSIKAGNDI
Position: 47-55
Source molecule (GenBank): Q3LXL6.1
Assay category: TCell
Result: Positive-Low
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: DENV2-NS3 (347-355)
Chemical type: Peptide from protein
Sequence: PSIKAGNDI
Position: 47-55
Source molecule (GenBank): Q3LXL6.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: DENV2-E (7-15)
Chemical type: Peptide from protein
Sequence: SNRDFVEGV
Position: 7-15
Source molecule (GenBank): AAM75194.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: DENV2-E (7-15)
Chemical type: Peptide from protein
Sequence: SNRDFVEGV
Position: 7-15
Source molecule (GenBank): AAM75194.1
Assay category: TCell
Result: Positive-Low
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: DENV2-NS5 (18-27)
Chemical type: Peptide from protein
Sequence: ESEVPNLDII
Position: 2759-2768
Source molecule (GenBank): AHG25310.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: DENV2-NS5 (18-27)
Chemical type: Peptide from protein
Sequence: ESEVPNLDII
Position: 2759-2768
Source molecule (GenBank): AHG25310.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: prM25-33
Chemical type: Peptide from protein
Sequence: TLGMNKCYI
Position: 150-158
Source molecule (GenBank): ALU33341.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: prM25-33
Chemical type: Peptide from protein
Sequence: TLGMNKCYI
Position: 150-158
Source molecule (GenBank): ALU33341.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-prM46-54
Chemical type: Peptide from protein
Sequence: MSYECPML
Position: 171-178
Source molecule (GenBank): APO08504.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-prM46-54
Chemical type: Peptide from protein
Sequence: MSYECPML
Position: 171-178
Source molecule (GenBank): APO08504.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-E48-56
Chemical type: Peptide, no natural source
Sequence: TTSVNMAEV
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-E48-56
Chemical type: Peptide, no natural source
Sequence: TTSVNMAEV
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-E57-65
Chemical type: Peptide from protein
Sequence: RSYCYEASI
Position: 57-65
Source molecule (GenBank): AIC06934.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-E57-65
Chemical type: Peptide from protein
Sequence: RSYCYEASI
Position: 57-65
Source molecule (GenBank): AIC06934.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MR-E310-317
Chemical type: Peptide from protein
Sequence: AAFTFTKI
Position: 310-317
Source molecule (GenBank): AIC06934.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MR-E310-317
Chemical type: Peptide from protein
Sequence: AAFTFTKI
Position: 310-317
Source molecule (GenBank): AIC06934.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-E345-355
Chemical type: Peptide from protein
Sequence: MAVDMQTLTPV
Position: 345-355
Source molecule (GenBank): AIC06934.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-E345-355
Chemical type: Peptide from protein
Sequence: MAVDMQTLTPV
Position: 345-355
Source molecule (GenBank): AIC06934.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-E420-428
Chemical type: Peptide from protein
Sequence: RMAVLGDTA
Position: 420-428
Source molecule (GenBank): AIC06934.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-E420-428
Chemical type: Peptide from protein
Sequence: RMAVLGDTA
Position: 420-428
Source molecule (GenBank): AIC06934.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MR-E494-502
Chemical type: Peptide from protein
Sequence: VMIFLSTAV
Position: 490-498
Source molecule (GenBank): YP_009227198.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MR-E494-502
Chemical type: Peptide from protein
Sequence: VMIFLSTAV
Position: 490-498
Source molecule (GenBank): YP_009227198.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS1 (174-183)
Chemical type: Peptide from protein
Sequence: YSLECDPAVI
Position: 969-978
Source molecule (GenBank): AMA12084.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS1 (174-183)
Chemical type: Peptide from protein
Sequence: YSLECDPAVI
Position: 969-978
Source molecule (GenBank): AMA12084.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS2A80-87
Chemical type: Peptide from protein
Sequence: VSFIFRAN
Position: 1237-1244
Source molecule (GenBank): AMA12084.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS2A80-87
Chemical type: Peptide from protein
Sequence: VSFIFRAN
Position: 1237-1244
Source molecule (GenBank): AMA12084.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS2A 179-188
Chemical type: Peptide from protein
Sequence: SVKKNLPFVM
Position: 1330-1339
Source molecule (GenBank): ANW07474.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS2A 179-188
Chemical type: Peptide from protein
Sequence: SVKKNLPFVM
Position: 1330-1339
Source molecule (GenBank): ANW07474.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS2B 114-122
Chemical type: Peptide from protein
Sequence: AAGAWYVYV
Position: 1483-1491
Source molecule (GenBank): ANW07474.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS2B 114-122
Chemical type: Peptide from protein
Sequence: AAGAWYVYV
Position: 1483-1491
Source molecule (GenBank): ANW07474.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS3 137-145
Chemical type: Peptide from protein
Sequence: VVIKNGSYV
Position: 154-162
Source molecule (GenBank): YP_009227202.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS3 137-145
Chemical type: Peptide from protein
Sequence: VVIKNGSYV
Position: 154-162
Source molecule (GenBank): YP_009227202.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS3 276-284
Chemical type: Peptide from protein
Sequence: SSIAARGYI
Position: 293-301
Source molecule (GenBank): YP_009227202.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS3 276-284
Chemical type: Peptide from protein
Sequence: SSIAARGYI
Position: 293-301
Source molecule (GenBank): YP_009227202.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS4A 135-142
Chemical type: Peptide from protein
Sequence: IMVAVGLL
Position: 2251-2258
Source molecule (GenBank): ANW07474.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS4A 135-142
Chemical type: Peptide from protein
Sequence: IMVAVGLL
Position: 2251-2258
Source molecule (GenBank): ANW07474.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS4B 102-110
Chemical type: Peptide from protein
Sequence: SQLTPLTLI
Position: 102-110
Source molecule (GenBank): YP_009227204.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS4B 102-110
Chemical type: Peptide from protein
Sequence: SQLTPLTLI
Position: 102-110
Source molecule (GenBank): YP_009227204.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS-NS5 68-77
Chemical type: Peptide from protein
Sequence: SSLVNGVVRL
Position: 320-329
Source molecule (GenBank): YP_001527887.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS-NS5 68-77
Chemical type: Peptide from protein
Sequence: SSLVNGVVRL
Position: 320-329
Source molecule (GenBank): YP_001527887.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MR-NS5 121-131
Chemical type: Peptide from protein
Sequence: RQVMNIVSSWL
Position: 2892-2902
Source molecule (GenBank): ANK57895.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MR-NS5 121-131
Chemical type: Peptide from protein
Sequence: RQVMNIVSSWL
Position: 2892-2902
Source molecule (GenBank): ANK57895.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS5 128-135
Chemical type: Peptide from protein
Sequence: SSWLWKEL
Position: 2893-2900
Source molecule (GenBank): ANW07474.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS5 128-135
Chemical type: Peptide from protein
Sequence: SSWLWKEL
Position: 2893-2900
Source molecule (GenBank): ANW07474.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS5 222-229
Chemical type: Peptide from protein
Sequence: RAIWYMWL
Position: 153-160
Source molecule (GenBank): ABA25478.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: FSS/MR-NS5 222-229
Chemical type: Peptide from protein
Sequence: RAIWYMWL
Position: 153-160
Source molecule (GenBank): ABA25478.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MR-NS5 449-557
Chemical type: Peptide from protein
Sequence: TGWSNWEEV
Position: 218-226
Source molecule (GenBank): AHL43473.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MR-NS5 449-557
Chemical type: Peptide from protein
Sequence: TGWSNWEEV
Position: 218-226
Source molecule (GenBank): AHL43473.1
Assay category: TCell
Result: Negative
Host:  5-6 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo