Reference: S Matsushita; S Fujisao; Y Nishimura. "Molecular mechanisms underlying HLA-DR-associated susceptibility to autoimmunity." International journal of cardiology. (1996).

Epitope: 0405BP3
Chemical type: Peptide from protein
Sequence: GSTVFDNLPNPEIDGDYYGW
Assay category: MhcLigandElution
Result: Positive

Epitope: 0405BP3
Chemical type: Peptide from protein
Sequence: GSTVFDNLPNPEIDGDYYGW
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3
Chemical type: Peptide from protein
Sequence: GSTVFDNLPNPEIDGDYYGW
Assay category: MhcBinding
Result: Positive

Epitope: HLA-DR4 eluted self peptide (likely source CD23)
Chemical type: Peptide from protein
Sequence: SGQLVSINN
Assay category: MhcLigandElution
Result: Positive

Epitope: HLA-DR4 eluted self peptide from CD20
Chemical type: Peptide from protein
Sequence: GPKPLFRRM
Position: 26-34
Source molecule (GenBank): P11836.1
Assay category: MhcLigandElution
Result: Positive

Epitope: HLA-DR4 eluted self peptide from pyruvate kinase
Chemical type: Peptide from protein
Sequence: SDPILYRPVAVALD
Position: 100-113
Source molecule (GenBank): P14618.4
Assay category: MhcLigandElution
Result: Positive

Epitope: PKM2p99-117
Chemical type: Peptide from protein
Sequence: SDPILYRPVAVALDTKGPE
Position: 100-118
Source molecule (GenBank): P14618.4
Assay category: MhcBinding
Result: Positive

Epitope: PKM2p99-117
Chemical type: Peptide from protein
Sequence: SDPILYRPVAVALDTKGPE
Position: 100-118
Source molecule (GenBank): P14618.4
Assay category: MhcBinding
Result: Positive

Epitope: DR9BP1
Chemical type: Peptide, no natural source
Sequence: ANDGATGWVASMSSAY
Assay category: MhcBinding
Result: Positive

Chemical type: Peptide, no natural source
Sequence: KWAASAAAAA
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP1
Chemical type: Peptide from protein
Sequence: VPIQRAVYQNVNN
Assay category: MhcLigandElution
Result: Positive

Epitope: 0405BP1
Chemical type: Peptide from protein
Sequence: VPIQRAVYQNVNN
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP1
Chemical type: Peptide from protein
Sequence: VPIQRAVYQNVNN
Assay category: MhcBinding
Result: Positive

Epitope: HLA-DR4 eluted self peptide (likely source CD23)
Chemical type: Peptide from protein
Sequence: EGQLVSI
Position: 195-201
Source molecule (GenBank): P06734.1
Assay category: MhcLigandElution
Result: Positive

Epitope: DR4 binding motif peptide
Chemical type: Peptide, no natural source
Sequence: AAFAALANAA
Assay category: MhcBinding
Result: Positive

Epitope: DR4 binding motif peptide
Chemical type: Peptide, no natural source
Sequence: AAFAALANAA
Assay category: MhcBinding
Result: Positive

Epitope: DR4 binding motif peptide
Chemical type: Peptide, no natural source
Sequence: AAYAALANAA
Assay category: MhcBinding
Result: Positive

Epitope: DR4 binding motif peptide
Chemical type: Peptide, no natural source
Sequence: AAYAALANAA
Assay category: MhcBinding
Result: Positive

Epitope: DR4 binding motif peptide
Chemical type: Peptide, no natural source
Sequence: AAYAAVAVAA
Assay category: MhcBinding
Result: Positive

Epitope: DR4 binding motif peptide
Chemical type: Peptide, no natural source
Sequence: AAYAAVAVAA
Assay category: MhcBinding
Result: Positive

Epitope: DR4 binding motif peptide
Chemical type: Peptide, no natural source
Sequence: AALAAIASAA
Assay category: MhcBinding
Result: Positive

Epitope: DR4 binding motif peptide
Chemical type: Peptide, no natural source
Sequence: AALAAIASAA
Assay category: MhcBinding
Result: Positive

Epitope: DR4 binding motif peptide
Chemical type: Peptide, no natural source
Sequence: AAFAAMASAA
Assay category: MhcBinding
Result: Positive

Epitope: DR4 binding motif peptide
Chemical type: Peptide, no natural source
Sequence: AAFAAMASAA
Assay category: MhcBinding
Result: Positive

Epitope: K-Insαp1-10
Chemical type: Peptide from protein
Sequence: GIVEQCCTSI
Position: 90-99
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Negative
MHC allele types: 409
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: K-Insαp1-10
Chemical type: Peptide from protein
Sequence: GIVEQCCTSI
Position: 90-99
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 500000.0

Epitope: K-Insαp1-10
Chemical type: Peptide from protein
Sequence: GIVEQCCTSI
Position: 90-99
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 500000.0

Epitope: K-Insαp8-21
Chemical type: Peptide from protein
Sequence: TSICSLYQLENYCN
Position: 97-110
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: K-Insαp8-21
Chemical type: Peptide from protein
Sequence: TSICSLYQLENYCN
Position: 97-110
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 4100.0

Epitope: K-Insαp8-21
Chemical type: Peptide from protein
Sequence: TSICSLYQLENYCN
Position: 97-110
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 180000.0

Epitope: K-Insßp1-18
Chemical type: Peptide from protein
Sequence: FVNQHLCGSHLVEALYLV
Position: 25-42
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Negative
MHC allele types: 409
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: K-Insßp1-18
Chemical type: Peptide from protein
Sequence: FVNQHLCGSHLVEALYLV
Position: 25-42
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 500000.0

Epitope: K-Insßp1-18
Chemical type: Peptide from protein
Sequence: FVNQHLCGSHLVEALYLV
Position: 25-42
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 500000.0

Epitope: K-Insßp11-30
Chemical type: Peptide from protein
Sequence: LVEALYLVCGERGFFYTPKT
Position: 35-54
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: K-Insßp11-30
Chemical type: Peptide from protein
Sequence: LVEALYLVCGERGFFYTPKT
Position: 35-54
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 14500.0

Epitope: K-Insßp11-30
Chemical type: Peptide from protein
Sequence: LVEALYLVCGERGFFYTPKT
Position: 35-54
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 15000.0

Epitope: 0405BP3 with C-terminal truncation
Chemical type: Peptide from protein
Sequence: GSTVFDNLPNPE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 with C-terminal truncation
Chemical type: Peptide from protein
Sequence: GSTVFDNLPNPE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog G1S
Chemical type: Peptide, no natural source
Sequence: SSTVFDNLPNPE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog G1S
Chemical type: Peptide, no natural source
Sequence: SSTVFDNLPNPE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog S2A
Chemical type: Peptide, no natural source
Sequence: GASTVFDNLPNPE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog S2A
Chemical type: Peptide, no natural source
Sequence: GASTVFDNLPNPE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog T3A
Chemical type: Peptide, no natural source
Sequence: GSAVFDNLPNPE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog T3A
Chemical type: Peptide, no natural source
Sequence: GSAVFDNLPNPE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog V4S
Chemical type: Peptide, no natural source
Sequence: GSTSFDNLPNPE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog V4S
Chemical type: Peptide, no natural source
Sequence: GSTSFDNLPNPE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog D6A
Chemical type: Peptide, no natural source
Sequence: GSTVFANLPNPE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog D6A
Chemical type: Peptide, no natural source
Sequence: GSTVFANLPNPE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog N7A
Chemical type: Peptide, no natural source
Sequence: GSTVFDALPNPE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog N7A
Chemical type: Peptide, no natural source
Sequence: GSTVFDALPNPE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog L8S
Chemical type: Peptide, no natural source
Sequence: GSTVFDNSPNPE
Assay category: MhcBinding
Result: Negative

Epitope: 0405BP3 analog L8S
Chemical type: Peptide, no natural source
Sequence: GSTVFDNSPNPE
Assay category: MhcBinding
Result: Negative

Epitope: 0405BP3 analog P9S
Chemical type: Peptide, no natural source
Sequence: GSTVFDNLSNPE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog P9S
Chemical type: Peptide, no natural source
Sequence: GSTVFDNLSNPE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog N10A
Chemical type: Peptide, no natural source
Sequence: GSTVFDNLPAPE
Assay category: MhcBinding
Result: Negative

Epitope: 0405BP3 analog N10A
Chemical type: Peptide, no natural source
Sequence: GSTVFDNLPAPE
Assay category: MhcBinding
Result: Negative

Epitope: 0405BP3 analog P11S
Chemical type: Peptide, no natural source
Sequence: GSTVFDNLPNSE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog P11S
Chemical type: Peptide, no natural source
Sequence: GSTVFDNLPNSE
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog E12A
Chemical type: Peptide, no natural source
Sequence: GSTVFDNLPNPA
Assay category: MhcBinding
Result: Positive

Epitope: 0405BP3 analog E12A
Chemical type: Peptide, no natural source
Sequence: GSTVFDNLPNPA
Assay category: MhcBinding
Result: Positive