Reference: Yi-Chun Isabella Tsai; Henrik Johansson; David Dixon; Stephen Martin; Chun-Wa Chung; Jane Clarkson; David House; Katrin Rittinger. "Single-Domain Antibodies as Crystallization Chaperones to Enable Structure-Based Inhibitor Development for RBR E3 Ubiquitin Ligases." Cell chemical biology (2020).

Epitope: Epitope of dAb3 dimer on RBR E3 ubiquitin ligase
Chemical type: Discontinuous protein residues
Discontinuous residues: R770, P775, Y778, H782, T786, R792, D793, P794, K795, F796, W798, A800, Q801, C802, S803, F804, Q819, C820, Q822, R827, C828, K829, R830, D852, E854, Y855, C874, Q892
Source molecule (GenBank): Q96EP0.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.47

Epitope: Epitope of dAb3 dimer on RBR E3 ubiquitin ligase
Chemical type: Discontinuous protein residues
Discontinuous residues: R770, P775, Y778, H782, T786, R792, D793, P794, K795, F796, W798, A800, Q801, C802, S803, F804, Q819, C820, Q822, R827, C828, K829, R830, D852, E854, Y855, C874, Q892
Source molecule (GenBank): Q96EP0.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.9

Epitope: Epitope of dAb3 dimer on RBR E3 ubiquitin ligase
Chemical type: Discontinuous protein residues
Discontinuous residues: R770, P775, Y778, H782, T786, R792, D793, P794, K795, F796, W798, A800, Q801, C802, S803, F804, Q819, C820, Q822, R827, C828, K829, R830, D852, E854, Y855, C874, Q892
Source molecule (GenBank): Q96EP0.1
Assay category: BCell
Result: Positive
Quantitative measurement: 940000.0

Epitope: Epitope of dAb3 dimer on RBR E3 ubiquitin ligase
Chemical type: Discontinuous protein residues
Discontinuous residues: R770, P775, Y778, H782, T786, R792, D793, P794, K795, F796, W798, A800, Q801, C802, S803, F804, Q819, C820, Q822, R827, C828, K829, R830, D852, E854, Y855, C874, Q892
Source molecule (GenBank): Q96EP0.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.083

Epitope: Epitope of dAb3 dimer on RBR E3 ubiquitin ligase
Chemical type: Discontinuous protein residues
Discontinuous residues: R770, P775, Y778, H782, T786, R792, D793, P794, K795, F796, W798, A800, Q801, C802, S803, F804, Q819, C820, Q822, R827, C828, K829, R830, D852, E854, Y855, C874, Q892
Source molecule (GenBank): Q96EP0.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.25

Epitope: Epitope of dAb3 dimer on RBR E3 ubiquitin ligase
Chemical type: Discontinuous protein residues
Discontinuous residues: R770, P775, Y778, H782, T786, R792, D793, P794, K795, F796, W798, A800, Q801, C802, S803, F804, Q819, C820, Q822, R827, C828, K829, R830, D852, E854, Y855, C874, Q892
Source molecule (GenBank): Q96EP0.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.106

Epitope: Epitope of dAb3 dimer on RBR E3 ubiquitin ligase
Chemical type: Discontinuous protein residues
Discontinuous residues: R770, P775, Y778, H782, T786, R792, D793, P794, K795, F796, W798, A800, Q801, C802, S803, F804, Q819, C820, Q822, R827, C828, K829, R830, D852, E854, Y855, C874, Q892
Source molecule (GenBank): Q96EP0.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.1

Epitope: Epitope of dAb3 dimer on RBR E3 ubiquitin ligase
Chemical type: Discontinuous protein residues
Discontinuous residues: R770, P775, Y778, H782, T786, R792, D793, P794, K795, F796, W798, A800, Q801, C802, S803, F804, Q819, C820, Q822, R827, C828, K829, R830, D852, E854, Y855, C874, Q892
Source molecule (GenBank): Q96EP0.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.56

Epitope: Epitope of dAb3 dimer on RBR E3 ubiquitin ligase
Chemical type: Discontinuous protein residues
Discontinuous residues: R770, P775, Y778, H782, T786, R792, D793, P794, K795, F796, W798, A800, Q801, C802, S803, F804, Q819, C820, Q822, R827, C828, K829, R830, D852, E854, Y855, C874, Q892
Source molecule (GenBank): Q96EP0.1
Assay category: BCell
Result: Positive

Epitope: Epitope of dAb3 dimer on RBR E3 ubiquitin ligase
Chemical type: Discontinuous protein residues
Discontinuous residues: R770, P775, Y778, H782, T786, R792, D793, P794, K795, F796, W798, A800, Q801, C802, S803, F804, Q819, C820, Q822, R827, C828, K829, R830, D852, E854, Y855, C874, Q892
Source molecule (GenBank): Q96EP0.1
Assay category: BCell
Result: Positive