Reference: Arthur S Kim; Natasha M Kafai; Emma S Winkler; Theron C Gilliland; Emily L Cottle; James T Earnest; Prashant N Jethva; Paulina Kaplonek; Aadit P Shah; Rachel H Fong; Edgar Davidson; Ryan J Malonis; Jose A Quiroz; Lauren E Williamson; Lo Vang; Matthias Mack; James E Crowe; Benjamin J Doranz; Jonathan R Lai; Galit Alter; Michael L Gross; William B Klimstra; Daved H Fremont; Michael S Diamond. "Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope." Cell (2021).

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-High

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-High

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-High

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-High

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-Low

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-Low

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive
Quantitative measurement: 240000.0

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00018

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-Low

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.112
Chemical type: Discontinuous protein residues
Discontinuous residues: W898, G900, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive
Quantitative measurement: 0.8

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-High

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-High

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-Low

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-High

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000020

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive
Quantitative measurement: 100000.0

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-Low

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive-Low

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive
Quantitative measurement: 5.4

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: E1-DC2.315
Chemical type: Discontinuous protein residues
Discontinuous residues: K861, V863, I864, K870, G892, V893, Y894, M897, Y902, F904, N909
Source molecule (GenBank): Q8JUX5
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00018

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive
Quantitative measurement: 240000.0

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive-High

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.8

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive-Low

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive-High

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive-High

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive-Low

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive-Low

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive-High

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive

Epitope: DC2.112_EEV_epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K50, Y51, K52, T53, K54, V55, P56, S57, P58, V59, V60, K61, V80, F81, T82, G83, V84, Y85, P86, F87, M88, W89, G90, G91, A92, Y93, C94, F95
Source molecule (GenBank): NP_740648.1
Assay category: BCell
Result: Positive