Reference: V L Heath; P Hutchings; D J Fowell; A Cooke; D W Mason. "Peptides derived from murine insulin are diabetogenic in both rats and mice, but the disease-inducing epitopes are different: evidence against a common environmental cross-reactivity in the pathogenicity of type 1 diabetes." Diabetes (1999).

Epitope: B1
Chemical type: Peptide from protein
Sequence: HLVEALYLVCGERGFFYTPK
Position: 34-53
Source molecule (GenBank): NP_062002.1
Assay category: TCell
Result: Negative
Host:  adult
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B1
Chemical type: Peptide from protein
Sequence: HLVEALYLVCGERGFFYTPK
Position: 34-53
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Positive
Host: M 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B2
Chemical type: Peptide from protein
Sequence: FVKQHLCGSHLVEALYLV
Position: 25-42
Source molecule (GenBank): NP_062003.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Short Term Restimulated

Epitope: B2
Chemical type: Peptide from protein
Sequence: FVKQHLCGSHLVEALYLV
Position: 25-42
Source molecule (GenBank): NP_062003.1
Assay category: TCell
Result: Positive
Host:  adult

Epitope: B2
Chemical type: Peptide from protein
Sequence: FVKQHLCGSHLVEALYLV
Position: 25-42
Source molecule (GenBank): NP_062003.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Short Term Restimulated

Epitope: B2
Chemical type: Peptide from protein
Sequence: FVKQHLCGSHLVEALYLV
Position: 25-42
Source molecule (GenBank): NP_062003.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B2
Chemical type: Peptide from protein
Sequence: FVKQHLCGSHLVEALYLV
Position: 25-42
Source molecule (GenBank): NP_062003.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Short Term Restimulated

Epitope: B2
Chemical type: Peptide from protein
Sequence: FVKQHLCGSHLVEALYLV
Position: 25-42
Source molecule (GenBank): NP_062003.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Short Term Restimulated

Epitope: B2
Chemical type: Peptide from protein
Sequence: FVKQHLCGSHLVEALYLV
Position: 25-42
Source molecule (GenBank): P01326.1
Assay category: TCell
Result: Negative
Host: M 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B3
Chemical type: Peptide from protein
Sequence: FVKQHLCGPHLVEALYLV
Position: 25-42
Source molecule (GenBank): NP_062002.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Short Term Restimulated

Epitope: B3
Chemical type: Peptide from protein
Sequence: FVKQHLCGPHLVEALYLV
Position: 25-42
Source molecule (GenBank): NP_062002.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Short Term Restimulated

Epitope: B3
Chemical type: Peptide from protein
Sequence: FVKQHLCGPHLVEALYLV
Position: 25-42
Source molecule (GenBank): NP_062002.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Short Term Restimulated

Epitope: B3
Chemical type: Peptide from protein
Sequence: FVKQHLCGPHLVEALYLV
Position: 25-42
Source molecule (GenBank): NP_062002.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Short Term Restimulated

Epitope: B3
Chemical type: Peptide from protein
Sequence: FVKQHLCGPHLVEALYLV
Position: 25-42
Source molecule (GenBank): NP_062002.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Short Term Restimulated

Epitope: B3
Chemical type: Peptide from protein
Sequence: FVKQHLCGPHLVEALYLV
Position: 25-42
Source molecule (GenBank): NP_062002.1
Assay category: TCell
Result: Positive
Host:  adult
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B3
Chemical type: Peptide from protein
Sequence: FVKQHLCGPHLVEALYLV
Position: 25-42
Source molecule (GenBank): NP_032412.3
Assay category: TCell
Result: Negative
Host: M 8-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo