Reference: Ikbel Naouar; Thouraya Boussoffara; Mehdi Chenik; Sami Gritli; Melika Ben Ahmed; Nabil Belhadj Hmida; Narges Bahi-Jaber; Rafika Bardi; Yousr Gorgi; Afif Ben Salah; Hechmi Louzir. "Prediction of T Cell Epitopes from Leishmania major Potentially Excreted/Secreted Proteins Inducing Granzyme B Production." PloS one (2016).

Epitope: A1
Chemical type: Peptide from protein
Sequence: ALQEETHVL
Position: 85-93
Source molecule (GenBank): XP_001687683.1
Assay category: MhcBinding
Result: Negative

Epitope: A2
Chemical type: Peptide from protein
Sequence: YMAQKAEEV
Position: 445-453
Source molecule (GenBank): XP_001687683.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: A3
Chemical type: Peptide from protein
Sequence: KLTVSSAAV
Position: 277-285
Source molecule (GenBank): XP_001687683.1
Assay category: MhcBinding
Result: Negative

Epitope: A4
Chemical type: Peptide from protein
Sequence: VLGSHVQTL
Position: 92-100
Source molecule (GenBank): XP_001687683.1
Assay category: MhcBinding
Result: Negative

Epitope: A6
Chemical type: Peptide from protein
Sequence: HLMGQLNEL
Position: 380-388
Source molecule (GenBank): XP_001687683.1
Assay category: MhcBinding
Result: Negative

Epitope: A7
Chemical type: Peptide from protein
Sequence: RLRDDLERL
Position: 107-115
Source molecule (GenBank): XP_001686666.1
Assay category: MhcBinding
Result: Negative

Epitope: A9
Chemical type: Peptide from protein
Sequence: NLIDFNFKL
Position: 198-206
Source molecule (GenBank): AAY89227.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: A10
Chemical type: Peptide from protein
Sequence: LLKDSFAFL
Position: 185-193
Source molecule (GenBank): AAY89227.1
Assay category: MhcBinding
Result: Negative

Epitope: A11
Chemical type: Peptide from protein
Sequence: CLLDSFKEL
Position: 230-238
Source molecule (GenBank): AAY89227.1
Assay category: MhcBinding
Result: Negative

Epitope: A12
Chemical type: Peptide from protein
Sequence: VLEENRTTL
Position: 167-175
Source molecule (GenBank): AAY89227.1
Assay category: MhcBinding
Result: Negative

Epitope: B1
Chemical type: Peptide from protein
Sequence: VLCALLFCV
Position: 9-17
Source molecule (GenBank): AAN75008.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: B2
Chemical type: Peptide from protein
Sequence: KLHPVYDKV
Position: 387-395
Source molecule (GenBank): AAN75008.1
Assay category: MhcBinding
Result: Negative

Epitope: B4
Chemical type: Peptide from protein
Sequence: KLHPVYDKV
Position: 387-395
Source molecule (GenBank): AAN75008.1
Assay category: MhcBinding
Result: Negative

Epitope: B5
Chemical type: Peptide from protein
Sequence: EMASMITKV
Position: 157-165
Source molecule (GenBank): AAN75008.1
Assay category: MhcBinding
Result: Negative

Epitope: B6
Chemical type: Peptide from protein
Sequence: DMLAGIATL
Position: 63-71
Source molecule (GenBank): AAN75008.1
Assay category: MhcBinding
Result: Negative

Epitope: B7
Chemical type: Peptide from protein
Sequence: LLSAQIARL
Position: 321-329
Source molecule (GenBank): AAY42352.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: B8
Chemical type: Peptide from protein
Sequence: LLFDELTAL
Position: 256-264
Source molecule (GenBank): AAY42352.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: B9
Chemical type: Peptide from protein
Sequence: RLMQCVQQL
Position: 737-745
Source molecule (GenBank): AAY42352.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: B10
Chemical type: Peptide from protein
Sequence: SLVVVSASL
Position: 33-41
Source molecule (GenBank): AAY42352.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: B11
Chemical type: Peptide from protein
Sequence: SLCRSLVVV
Position: 29-37
Source molecule (GenBank): AAY42352.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: B12
Chemical type: Peptide from protein
Sequence: HLVAPLASL
Position: 22-30
Source molecule (GenBank): AAY42352.1
Assay category: MhcBinding
Result: Negative

Epitope: C1
Chemical type: Peptide from protein
Sequence: ALNDALWAV
Position: 395-403
Source molecule (GenBank): XP_001685653.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: C2
Chemical type: Peptide from protein
Sequence: RLLVDLAQL
Position: 77-85
Source molecule (GenBank): XP_001685653.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: C4
Chemical type: Peptide from protein
Sequence: VIAGTSNAV
Position: 367-375
Source molecule (GenBank): XP_001685653.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: C5
Chemical type: Peptide from protein
Sequence: AMREALRYL
Position: 128-136
Source molecule (GenBank): XP_001685653.1
Assay category: MhcBinding
Result: Negative

Epitope: C6
Chemical type: Peptide from protein
Sequence: GVFDAAISI
Position: 212-220
Source molecule (GenBank): XP_001686842.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: C8
Chemical type: Peptide from protein
Sequence: GLDYSEELL
Position: 144-152
Source molecule (GenBank): XP_001686842.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: C9
Chemical type: Peptide from protein
Sequence: RVAASVAAV
Position: 111-119
Source molecule (GenBank): AAY89228.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: C11
Chemical type: Peptide from protein
Sequence: TIPSFIVRV
Position: 141-149
Source molecule (GenBank): XP_001680975.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: C12
Chemical type: Peptide from protein
Sequence: RLLEGSAIM
Position: 68-76
Source molecule (GenBank): XP_001680975.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: D1
Chemical type: Peptide from protein
Sequence: LIQQRHIAV
Position: 127-135
Source molecule (GenBank): XP_001680975.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: D2
Chemical type: Peptide from protein
Sequence: AVAKQIVTI
Position: 134-142
Source molecule (GenBank): XP_001680975.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: D3
Chemical type: Peptide from protein
Sequence: ILERRLQTI
Position: 103-111
Source molecule (GenBank): XP_001680975.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: D4
Chemical type: Peptide from protein
Sequence: NMMAVVGLL
Position: 24-32
Source molecule (GenBank): XP_003721772.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: D5
Chemical type: Peptide from protein
Sequence: KLEDEVFAL
Position: 1086-1094
Source molecule (GenBank): AAY42351.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: D6
Chemical type: Peptide from protein
Sequence: ELLGNLEEV
Position: 1142-1150
Source molecule (GenBank): AAY42351.1
Assay category: MhcBinding
Result: Positive-High

Epitope: D7
Chemical type: Peptide from protein
Sequence: RMADEVQRL
Position: 496-504
Source molecule (GenBank): AAY42351.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: D8
Chemical type: Peptide from protein
Sequence: RLAVSLHEL
Position: 385-393
Source molecule (GenBank): AAY42351.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: D9
Chemical type: Peptide from protein
Sequence: LLGPAYQSI
Position: 454-462
Source molecule (GenBank): AAY42351.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: D10
Chemical type: Peptide from protein
Sequence: VIAEEPLYV
Position: 587-595
Source molecule (GenBank): AAY42351.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: D11
Chemical type: Peptide from protein
Sequence: PLSAVISPV
Position: 291-299
Source molecule (GenBank): AAY42351.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: D12
Chemical type: Peptide from protein
Sequence: LLPAPLVSV
Position: 320-328
Source molecule (GenBank): AAY42350.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: D12
Chemical type: Peptide from protein
Sequence: LLPAPLVSV
Position: 320-328
Source molecule (GenBank): AAY42350.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: E1
Chemical type: Peptide from protein
Sequence: MLLWTAVAV
Position: 575-583
Source molecule (GenBank): AAY42350.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E1
Chemical type: Peptide from protein
Sequence: MLLWTAVAV
Position: 575-583
Source molecule (GenBank): AAY42350.1
Assay category: MhcBinding
Result: Positive-High

Epitope: E2
Chemical type: Peptide from protein
Sequence: YLRTFPAAL
Position: 135-143
Source molecule (GenBank): AAY42350.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E2
Chemical type: Peptide from protein
Sequence: YLRTFPAAL
Position: 135-143
Source molecule (GenBank): AAY42350.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: E3
Chemical type: Peptide from protein
Sequence: RLAGFLAGL
Position: 336-344
Source molecule (GenBank): AAY89230.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E3
Chemical type: Peptide from protein
Sequence: RLAGFLAGL
Position: 336-344
Source molecule (GenBank): AAY89230.1
Assay category: MhcBinding
Result: Negative

Epitope: E4
Chemical type: Peptide from protein
Sequence: CLALIAWRV
Position: 385-393
Source molecule (GenBank): AAY89230.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E4
Chemical type: Peptide from protein
Sequence: CLALIAWRV
Position: 385-393
Source molecule (GenBank): AAY89230.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: E5
Chemical type: Peptide from protein
Sequence: VVAGMLRWV
Position: 69-77
Source molecule (GenBank): AAY89230.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E5
Chemical type: Peptide from protein
Sequence: VVAGMLRWV
Position: 69-77
Source molecule (GenBank): AAY89230.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: E6
Chemical type: Peptide from protein
Sequence: PLSPATRRL
Position: 143-151
Source molecule (GenBank): AAY89230.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E6
Chemical type: Peptide from protein
Sequence: PLSPATRRL
Position: 143-151
Source molecule (GenBank): AAY89230.1
Assay category: MhcBinding
Result: Negative

Epitope: E7
Chemical type: Peptide from protein
Sequence: MVLNAMAWL
Position: 92-100
Source molecule (GenBank): AAY89230.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E7
Chemical type: Peptide from protein
Sequence: MVLNAMAWL
Position: 92-100
Source molecule (GenBank): AAY89230.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: E8
Chemical type: Peptide from protein
Sequence: KIMEAITVV
Position: 53-61
Source molecule (GenBank): XP_001684092.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: E9
Chemical type: Peptide from protein
Sequence: FLAYDKFLL
Position: 115-123
Source molecule (GenBank): XP_001684092.1
Assay category: MhcBinding
Result: Negative

Epitope: E10
Chemical type: Peptide from protein
Sequence: HIFDRVAGV
Position: 461-469
Source molecule (GenBank): AAY42349.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: E11
Chemical type: Peptide from protein
Sequence: ALNQFTKVL
Position: 75-83
Source molecule (GenBank): XP_001680956.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: E12
Chemical type: Peptide from protein
Sequence: AIVKDMARL
Position: 179-187
Source molecule (GenBank): XP_001680956.1
Assay category: MhcBinding
Result: Negative

Epitope: F1
Chemical type: Peptide from protein
Sequence: GLQEVTRAI
Position: 136-144
Source molecule (GenBank): XP_001680956.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: F2
Chemical type: Peptide from protein
Sequence: VIANNVDPV
Position: 153-161
Source molecule (GenBank): XP_001680956.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: F3
Chemical type: Peptide from protein
Sequence: TLKNLIRSV
Position: 211-219
Source molecule (GenBank): XP_001680956.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: F4
Chemical type: Peptide from protein
Sequence: TLLDALGML
Position: 215-223
Source molecule (GenBank): XP_001682260.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: F4
Chemical type: Peptide from protein
Sequence: TLLDALGML
Position: 215-223
Source molecule (GenBank): XP_001682260.1
Assay category: MhcBinding
Result: Negative

Epitope: F5
Chemical type: Peptide from protein
Sequence: ALLAFTLGV
Position: 137-145
Source molecule (GenBank): XP_001682260.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: F5
Chemical type: Peptide from protein
Sequence: ALLAFTLGV
Position: 137-145
Source molecule (GenBank): XP_001682260.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: F6
Chemical type: Peptide from protein
Sequence: TLGVKQMVV
Position: 142-150
Source molecule (GenBank): XP_001682260.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: F6
Chemical type: Peptide from protein
Sequence: TLGVKQMVV
Position: 142-150
Source molecule (GenBank): XP_001682260.1
Assay category: MhcBinding
Result: Positive-High

Epitope: F7
Chemical type: Peptide from protein
Sequence: KLVRELFRV
Position: 263-271
Source molecule (GenBank): XP_001681853.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: F7
Chemical type: Peptide from protein
Sequence: KLVRELFRV
Position: 263-271
Source molecule (GenBank): XP_001681853.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: F8
Chemical type: Peptide from protein
Sequence: TMLELLTQL
Position: 306-314
Source molecule (GenBank): XP_001681853.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: F8
Chemical type: Peptide from protein
Sequence: TMLELLTQL
Position: 306-314
Source molecule (GenBank): XP_001681853.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: F9
Chemical type: Peptide from protein
Sequence: ALRERRMKV
Position: 404-412
Source molecule (GenBank): XP_001681853.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: F9
Chemical type: Peptide from protein
Sequence: ALRERRMKV
Position: 404-412
Source molecule (GenBank): XP_001681853.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: F10
Chemical type: Peptide from protein
Sequence: LLHDRQHSI
Position: 149-157
Source molecule (GenBank): XP_001681853.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: F10
Chemical type: Peptide from protein
Sequence: LLHDRQHSI
Position: 149-157
Source molecule (GenBank): XP_001681853.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: F11
Chemical type: Peptide from protein
Sequence: GLEQQIQEI
Position: 187-195
Source molecule (GenBank): XP_001681853.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: F11
Chemical type: Peptide from protein
Sequence: GLEQQIQEI
Position: 187-195
Source molecule (GenBank): XP_001681853.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: F12
Chemical type: Peptide from protein
Sequence: MLQTNSLAL
Position: 150-158
Source molecule (GenBank): AAY42348.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: F12
Chemical type: Peptide from protein
Sequence: MLQTNSLAL
Position: 150-158
Source molecule (GenBank): AAY42348.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: G1
Chemical type: Peptide from protein
Sequence: SLQFSAFLL
Position: 24-32
Source molecule (GenBank): AAY42348.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: G1
Chemical type: Peptide from protein
Sequence: SLQFSAFLL
Position: 24-32
Source molecule (GenBank): AAY42348.1
Assay category: MhcBinding
Result: Positive-High

Epitope: G2
Chemical type: Peptide from protein
Sequence: FMEVFGMLV
Position: 77-85
Source molecule (GenBank): AAY42348.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: G2
Chemical type: Peptide from protein
Sequence: FMEVFGMLV
Position: 77-85
Source molecule (GenBank): AAY42348.1
Assay category: MhcBinding
Result: Positive-High

Epitope: G3
Chemical type: Peptide from protein
Sequence: MLVQSCTSI
Position: 83-91
Source molecule (GenBank): AAY42348.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: G3
Chemical type: Peptide from protein
Sequence: MLVQSCTSI
Position: 83-91
Source molecule (GenBank): AAY42348.1
Assay category: MhcBinding
Result: Positive-High

Epitope: G5
Chemical type: Peptide from protein
Sequence: WIPPVVSVL
Position: 106-114
Source molecule (GenBank): AAY42348.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: G5
Chemical type: Peptide from protein
Sequence: WIPPVVSVL
Position: 106-114
Source molecule (GenBank): AAY42348.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: G6
Chemical type: Peptide from protein
Sequence: KIYQIGRSV
Position: 286-294
Source molecule (GenBank): XP_001685639.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: G6
Chemical type: Peptide from protein
Sequence: KIYQIGRSV
Position: 286-294
Source molecule (GenBank): XP_001685639.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: G7
Chemical type: Peptide from protein
Sequence: QLNKKIYQI
Position: 282-290
Source molecule (GenBank): XP_001685639.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: G7
Chemical type: Peptide from protein
Sequence: QLNKKIYQI
Position: 282-290
Source molecule (GenBank): XP_001685639.1
Assay category: MhcBinding
Result: Negative