Reference: Adriana Irimia; Andreia M Serra; Anita Sarkar; Ronald Jacak; Oleksandr Kalyuzhniy; Devin Sok; Karen L Saye-Francisco; Torben Schiffner; Ryan Tingle; Michael Kubitz; Yumiko Adachi; Robyn L Stanfield; Marc C Deller; Dennis R Burton; William R Schief; Ian A Wilson. "Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design." PLoS pathogens (2017).

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.07

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0112

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0164

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.17

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.03

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000211

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1300000.0

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00016

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000040

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2800000.0

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000046

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 559000.0

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.123

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3570000.0

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3170000.0

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0285

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000904

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.62

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.62

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.1

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.37

Epitope: Epitope of 10E8 WT and mutant Fabs on MPER/T117v2 scaffold
Chemical type: Discontinuous protein residues
Discontinuous residues: N646, W647, F648, T651, N652, L654, W655
Source molecule (GenBank): ADZ13338.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.379