Reference: Louise C Rowntree; Jennifer Audsley; Lilith F Allen; Hayley A McQuilten; Ruth R Hagen; Priyanka Chaurasia; Jan Petersen; Dene R Littler; Hyon-Xhi Tan; Lydia Murdiyarso; Jennifer R Habel; Isabelle J H Foo; Wuji Zhang; Elizabeth R V Ten Berge; Hanujah Ganesh; Prathanporn Kaewpreedee; Kelly W K Lee; Samuel M S Cheng; Janette S Y Kwok; Dhilshan Jayasinghe; Stephanie Gras; Jennifer A Juno; Adam K Wheatley; Stephen J Kent; Jamie Rossjohn; Allen C Cheng; Tom C Kotsimbos; Jason A Trubiano; Natasha E Holmes; Ken Ka Pang Chan; David S C Hui; Malik Peiris; Leo L M Poon; Sharon R Lewin; Peter C Doherty; Irani Thevarajan; Sophie A Valkenburg; Katherine Kedzierska; Thi H O Nguyen. "SARS-CoV-2-specific CD8<sup>+</sup> T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years." Proceedings of the National Academy of Sciences of the United States of America (2024).

Epitope: ORF1a1637
Chemical type: Peptide from protein
Sequence: TTDPSFLGRY
Position: 1637-1646
Source molecule (GenBank): P0DTC1.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: ORF1a1637
Chemical type: Peptide from protein
Sequence: TTDPSFLGRY
Position: 1637-1646
Source molecule (GenBank): P0DTC1.1
Assay category: TCell
Result: Positive-High
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: ORF1a1637
Chemical type: Peptide from protein
Sequence: TTDPSFLGRY
Position: 1637-1646
Source molecule (GenBank): P0DTC1.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S865
Chemical type: Peptide from protein
Sequence: LTDEMIAQY
Position: 865-873
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S865
Chemical type: Peptide from protein
Sequence: LTDEMIAQY
Position: 865-873
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S865
Chemical type: Peptide from protein
Sequence: LTDEMIAQY
Position: 865-873
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S269
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S269
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S269
Chemical type: Peptide from protein
Sequence: YLQPRTFLL
Position: 269-277
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N361
Chemical type: Peptide from protein
Sequence: KTFPPTEPK
Position: 361-369
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N361
Chemical type: Peptide from protein
Sequence: KTFPPTEPK
Position: 361-369
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N361
Chemical type: Peptide from protein
Sequence: KTFPPTEPK
Position: 361-369
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S378
Chemical type: Peptide from protein
Sequence: KCYGVSPTK
Position: 378-386
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S378
Chemical type: Peptide from protein
Sequence: KCYGVSPTK
Position: 378-386
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S378
Chemical type: Peptide from protein
Sequence: KCYGVSPTK
Position: 378-386
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N105
Chemical type: Peptide from protein
Sequence: SPRWYFYYL
Position: 105-113
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N105
Chemical type: Peptide from protein
Sequence: SPRWYFYYL
Position: 105-113
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N105
Chemical type: Peptide from protein
Sequence: SPRWYFYYL
Position: 105-113
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S919
Chemical type: Peptide from protein
Sequence: NQKLIANQF
Position: 919-927
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S919
Chemical type: Peptide from protein
Sequence: NQKLIANQF
Position: 919-927
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S919
Chemical type: Peptide from protein
Sequence: NQKLIANQF
Position: 919-927
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N9
Chemical type: Peptide from protein
Sequence: QRNAPRITF
Position: 9-17
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N9
Chemical type: Peptide from protein
Sequence: QRNAPRITF
Position: 9-17
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: N9
Chemical type: Peptide from protein
Sequence: QRNAPRITF
Position: 9-17
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S167
Chemical type: Peptide from protein
Sequence: TFEYVSQPFLMDLE
Position: 167-180
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S167
Chemical type: Peptide from protein
Sequence: TFEYVSQPFLMDLE
Position: 167-180
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S167
Chemical type: Peptide from protein
Sequence: TFEYVSQPFLMDLE
Position: 167-180
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S751
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNRAL
Position: 751-767
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S751
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNRAL
Position: 751-767
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S751
Chemical type: Peptide from protein
Sequence: NLLLQYGSFCTQLNRAL
Position: 751-767
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo