Reference: William D Tolbert; Neelakshi Gohain; Nirmin Alsahafi; Verna Van; Chiara Orlandi; Shilei Ding; Loïc Martin; Andrés Finzi; George K Lewis; Krishanu Ray; Marzena Pazgier. "Targeting the Late Stage of HIV-1 Entry for Antibody-Dependent Cellular Cytotoxicity: Structural Basis for Env Epitopes in the C11 Region." Structure (London, England : 1993) (2017).

Epitope: Epitope of N5-i5 Fab on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: T50, L51, F52, C53, S55, A57, K58, A59, V67, W68, A69, T70, H71, A72, C73, V74, P75, T76, D77, P78, N79, Q102, E105, D106, S109, Q113, Y219, T221, P222, A223
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of N5-i5 Fab on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: T50, L51, F52, C53, S55, A57, K58, A59, V67, W68, A69, T70, H71, A72, C73, V74, P75, T76, D77, P78, N79, Q102, E105, D106, S109, Q113, Y219, T221, P222, A223
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of N5-i5 Fab on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: T50, L51, F52, C53, S55, A57, K58, A59, V67, W68, A69, T70, H71, A72, C73, V74, P75, T76, D77, P78, N79, Q102, E105, D106, S109, Q113, Y219, T221, P222, A223
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.92

Epitope: Epitope of N12-i3 Fab on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: S30, D31, N32, L33, W34, V35, T36, V37, Y38, Y39, V41, P42, Q81, I83, H84, L85, E86, V226, S246, V247, Q248, I485
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.25

Epitope: Epitope of N12-i3 Fab on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: S30, D31, N32, L33, W34, V35, T36, V37, Y38, Y39, V41, P42, Q81, I83, H84, L85, E86, V226, S246, V247, Q248, I485
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.92

Epitope: Epitope of N12-i3 Fab on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: S30, D31, N32, L33, W34, V35, T36, V37, Y38, Y39, V41, P42, Q81, I83, H84, L85, E86, V226, S246, V247, Q248, I485
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of N12-i3 Fab on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: S30, D31, N32, L33, W34, V35, T36, V37, Y38, Y39, V41, P42, Q81, I83, H84, L85, E86, V226, S246, V247, Q248, I485
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive

Epitope: Epitope of N12-i3 Fab on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: S30, D31, N32, L33, W34, V35, T36, V37, Y38, Y39, V41, P42, Q81, I83, H84, L85, E86, V226, S246, V247, Q248, I485
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1000000.0

Epitope: Epitope of N12-i3 Fab on HIV-1 gp120
Chemical type: Discontinuous protein residues
Discontinuous residues: S30, D31, N32, L33, W34, V35, T36, V37, Y38, Y39, V41, P42, Q81, I83, H84, L85, E86, V226, S246, V247, Q248, I485
Source molecule (GenBank): Q0ED31.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000024