Reference: Matthias Zehner; Mira Alt; Artem Ashurov; Jory A Goldsmith; Rebecca Spies; Nina Weiler; Justin Lerma; Lutz Gieselmann; Dagmar Stöhr; Henning Gruell; Eric P Schultz; Christoph Kreer; Linda Schlachter; Hanna Janicki; Kerstin Laib Sampaio; Cora Stegmann; Michelle D Nemetchek; Sabrina Dähling; Leon Ullrich; Ulf Dittmer; Oliver Witzke; Manuel Koch; Brent J Ryckman; Ramin Lotfi; Jason S McLellan; Adalbert Krawczyk; Christian Sinzger; Florian Klein. "Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer." Immunity (2023).

Epitope: Epitope of Fab CS2it1p2_F7K on HCMV trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: E90, F91, Q93, Y95, I101, N103, L211, R214, Y215, Q217, R218, N219, T221, Y225, V237, P238, K239, Y240, I241, G243, T244
Source molecule (GenBank): P16750.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS2it1p2_F7K on HCMV trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: E90, F91, Q93, Y95, I101, N103, L211, R214, Y215, Q217, R218, N219, T221, Y225, V237, P238, K239, Y240, I241, G243, T244
Source molecule (GenBank): P16750.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS2it1p2_F7K on HCMV trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: E90, F91, Q93, Y95, I101, N103, L211, R214, Y215, Q217, R218, N219, T221, Y225, V237, P238, K239, Y240, I241, G243, T244
Source molecule (GenBank): P16750.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS2it1p2_F7K on HCMV trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: E90, F91, Q93, Y95, I101, N103, L211, R214, Y215, Q217, R218, N219, T221, Y225, V237, P238, K239, Y240, I241, G243, T244
Source molecule (GenBank): P16750.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS2it1p2_F7K on HCMV trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: E90, F91, Q93, Y95, I101, N103, L211, R214, Y215, Q217, R218, N219, T221, Y225, V237, P238, K239, Y240, I241, G243, T244
Source molecule (GenBank): P16750.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS2it1p2_F7K on HCMV trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: E90, F91, Q93, Y95, I101, N103, L211, R214, Y215, Q217, R218, N219, T221, Y225, V237, P238, K239, Y240, I241, G243, T244
Source molecule (GenBank): P16750.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS2it1p2_F7K on HCMV trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: E90, F91, Q93, Y95, I101, N103, L211, R214, Y215, Q217, R218, N219, T221, Y225, V237, P238, K239, Y240, I241, G243, T244
Source molecule (GenBank): P16750.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS2it1p2_F7K on HCMV trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: E90, F91, Q93, Y95, I101, N103, L211, R214, Y215, Q217, R218, N219, T221, Y225, V237, P238, K239, Y240, I241, G243, T244
Source molecule (GenBank): P16750.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS2it1p2_F7K on HCMV trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: E90, F91, Q93, Y95, I101, N103, L211, R214, Y215, Q217, R218, N219, T221, Y225, V237, P238, K239, Y240, I241, G243, T244
Source molecule (GenBank): P16750.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS2it1p2_F7K on HCMV trimer
Chemical type: Discontinuous protein residues
Discontinuous residues: E90, F91, Q93, Y95, I101, N103, L211, R214, Y215, Q217, R218, N219, T221, Y225, V237, P238, K239, Y240, I241, G243, T244
Source molecule (GenBank): P16750.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS4tt1p1_E3K on HCMV trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E54, Q58, C59, Y61, S64, L65, R66, N67; B: R53, C54, L55, L56, G57, E58, V59, F60, Q61
Source molecule (GenBank): AFR55394.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS4tt1p1_E3K on HCMV trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E54, Q58, C59, Y61, S64, L65, R66, N67; B: R53, C54, L55, L56, G57, E58, V59, F60, Q61
Source molecule (GenBank): AFR55394.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS4tt1p1_E3K on HCMV trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E54, Q58, C59, Y61, S64, L65, R66, N67; B: R53, C54, L55, L56, G57, E58, V59, F60, Q61
Source molecule (GenBank): AFR55394.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS4tt1p1_E3K on HCMV trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E54, Q58, C59, Y61, S64, L65, R66, N67; B: R53, C54, L55, L56, G57, E58, V59, F60, Q61
Source molecule (GenBank): AFR55394.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS4tt1p1_E3K on HCMV trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E54, Q58, C59, Y61, S64, L65, R66, N67; B: R53, C54, L55, L56, G57, E58, V59, F60, Q61
Source molecule (GenBank): AFR55394.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS4tt1p1_E3K on HCMV trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E54, Q58, C59, Y61, S64, L65, R66, N67; B: R53, C54, L55, L56, G57, E58, V59, F60, Q61
Source molecule (GenBank): AFR55394.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS4tt1p1_E3K on HCMV trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E54, Q58, C59, Y61, S64, L65, R66, N67; B: R53, C54, L55, L56, G57, E58, V59, F60, Q61
Source molecule (GenBank): AFR55394.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS4tt1p1_E3K on HCMV trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E54, Q58, C59, Y61, S64, L65, R66, N67; B: R53, C54, L55, L56, G57, E58, V59, F60, Q61
Source molecule (GenBank): AFR55394.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS4tt1p1_E3K on HCMV trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E54, Q58, C59, Y61, S64, L65, R66, N67; B: R53, C54, L55, L56, G57, E58, V59, F60, Q61
Source molecule (GenBank): AFR55394.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS4tt1p1_E3K on HCMV trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E54, Q58, C59, Y61, S64, L65, R66, N67; B: R53, C54, L55, L56, G57, E58, V59, F60, Q61
Source molecule (GenBank): AFR55394.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS4tt1p1_E3K on HCMV trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E54, Q58, C59, Y61, S64, L65, R66, N67; B: R53, C54, L55, L56, G57, E58, V59, F60, Q61
Source molecule (GenBank): AFR55394.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS4tt1p1_E3K on HCMV trimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: E54, Q58, C59, Y61, S64, L65, R66, N67; B: R53, C54, L55, L56, G57, E58, V59, F60, Q61
Source molecule (GenBank): AFR55394.1
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS2pt1p2_A10L on HCMV pentamer
Chemical type: Discontinuous protein residues
Discontinuous residues: E32, I34, N35, V36, P39, P40, R51, F52, Y65, S66, P67, E68, K69, T70, E72, G75, I76
Source molecule (GenBank): Q38LY2
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS2pt1p2_A10L on HCMV pentamer
Chemical type: Discontinuous protein residues
Discontinuous residues: E32, I34, N35, V36, P39, P40, R51, F52, Y65, S66, P67, E68, K69, T70, E72, G75, I76
Source molecule (GenBank): Q38LY2
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS2pt1p2_A10L on HCMV pentamer
Chemical type: Discontinuous protein residues
Discontinuous residues: E32, I34, N35, V36, P39, P40, R51, F52, Y65, S66, P67, E68, K69, T70, E72, G75, I76
Source molecule (GenBank): Q38LY2
Assay category: BCell
Result: Positive
Host: F

Epitope: Epitope of Fab CS2pt1p2_A10L on HCMV pentamer
Chemical type: Discontinuous protein residues
Discontinuous residues: E32, I34, N35, V36, P39, P40, R51, F52, Y65, S66, P67, E68, K69, T70, E72, G75, I76
Source molecule (GenBank): Q38LY2
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab CS2pt1p2_A10L on HCMV pentamer
Chemical type: Discontinuous protein residues
Discontinuous residues: E32, I34, N35, V36, P39, P40, R51, F52, Y65, S66, P67, E68, K69, T70, E72, G75, I76
Source molecule (GenBank): Q38LY2
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS2pt1p2_A10L on HCMV pentamer
Chemical type: Discontinuous protein residues
Discontinuous residues: E32, I34, N35, V36, P39, P40, R51, F52, Y65, S66, P67, E68, K69, T70, E72, G75, I76
Source molecule (GenBank): Q38LY2
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS2pt1p2_A10L on HCMV pentamer
Chemical type: Discontinuous protein residues
Discontinuous residues: E32, I34, N35, V36, P39, P40, R51, F52, Y65, S66, P67, E68, K69, T70, E72, G75, I76
Source molecule (GenBank): Q38LY2
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS3pt1p4_C1L on HCMV pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: C: R42, Y44, D45, R57, P59, T85, Q87, V88, N91; D: T167, R168, Y169, Q170, M171, E198, N200, Q202
Source molecule (GenBank): Q38LY2
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS3pt1p4_C1L on HCMV pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: C: R42, Y44, D45, R57, P59, T85, Q87, V88, N91; D: T167, R168, Y169, Q170, M171, E198, N200, Q202
Source molecule (GenBank): Q38LY2
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS3pt1p4_C1L on HCMV pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: C: R42, Y44, D45, R57, P59, T85, Q87, V88, N91; D: T167, R168, Y169, Q170, M171, E198, N200, Q202
Source molecule (GenBank): Q38LY2
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS3pt1p4_C1L on HCMV pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: C: R42, Y44, D45, R57, P59, T85, Q87, V88, N91; D: T167, R168, Y169, Q170, M171, E198, N200, Q202
Source molecule (GenBank): Q38LY2
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS3pt1p4_C1L on HCMV pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: C: R42, Y44, D45, R57, P59, T85, Q87, V88, N91; D: T167, R168, Y169, Q170, M171, E198, N200, Q202
Source molecule (GenBank): Q38LY2
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab CS3pt1p4_C1L on HCMV pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: C: R42, Y44, D45, R57, P59, T85, Q87, V88, N91; D: T167, R168, Y169, Q170, M171, E198, N200, Q202
Source molecule (GenBank): Q38LY2
Assay category: BCell
Result: Positive
Host:  45-72 years

Epitope: Epitope of Fab CS3pt1p4_C1L on HCMV pentamer
Chemical type: Region on multi-chain protein
Discontinuous residues: C: R42, Y44, D45, R57, P59, T85, Q87, V88, N91; D: T167, R168, Y169, Q170, M171, E198, N200, Q202
Source molecule (GenBank): Q38LY2
Assay category: BCell
Result: Positive
Host:  45-72 years