Reference: C Rizou; J P Ioannidis; E Panou-Pomonis; M Sakarellos-Daitsiotis; C Sakarellos; H M Moutsopoulos; P G Vlachoyiannopoulos. "B-Cell epitope mapping of DNA topoisomerase I defines epitopes strongly associated with pulmonary fibrosis in systemic sclerosis." American journal of respiratory cell and molecular biology (2000).

Epitope: Peptide 7
Chemical type: Peptide from protein
Sequence: SSEKHKDKHKDRDKEKRKEE
Position: 73-92
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 7
Chemical type: Peptide from protein
Sequence: SSEKHKDKHKDRDKEKRKEE
Position: 73-92
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 14
Chemical type: Peptide from protein
Sequence: TKKEKKRKLEEEEDGKLKKP
Position: 157-176
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 14
Chemical type: Peptide from protein
Sequence: TKKEKKRKLEEEEDGKLKKP
Position: 157-176
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 21
Chemical type: Peptide from protein
Sequence: YYDGKVMKLSPKAEEVATFF
Position: 241-260
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 21
Chemical type: Peptide from protein
Sequence: YYDGKVMKLSPKAEEVATFF
Position: 241-260
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 23
Chemical type: Peptide from protein
Sequence: DHEYTTKEIFRKNFFKDWRK
Position: 265-284
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 23
Chemical type: Peptide from protein
Sequence: DHEYTTKEIFRKNFFKDWRK
Position: 265-284
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 26
Chemical type: Peptide from protein
Sequence: DFTQMSQYFKAQTEARKQMS
Position: 301-320
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 26
Chemical type: Peptide from protein
Sequence: DFTQMSQYFKAQTEARKQMS
Position: 301-320
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 33
Chemical type: Peptide from protein
Sequence: NCSKDAKVPSPPPGHKWKEV
Position: 385-404
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 33
Chemical type: Peptide from protein
Sequence: NCSKDAKVPSPPPGHKWKEV
Position: 385-404
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 34
Chemical type: Peptide from protein
Sequence: PGHKWKEVRHDNKVTWLVSW
Position: 397-416
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Positive

Epitope: Peptide 34
Chemical type: Peptide from protein
Sequence: PGHKWKEVRHDNKVTWLVSW
Position: 397-416
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 40
Chemical type: Peptide from protein
Sequence: EMKVRQRAVALYFIDKLALR
Position: 469-488
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 40
Chemical type: Peptide from protein
Sequence: EMKVRQRAVALYFIDKLALR
Position: 469-488
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 41
Chemical type: Peptide from protein
Sequence: FIDKLALRAGNEKEEGETAD
Position: 481-500
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 41
Chemical type: Peptide from protein
Sequence: FIDKLALRAGNEKEEGETAD
Position: 481-500
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 45
Chemical type: Peptide from protein
Sequence: FLGKDSIRYYNKVPVEKRVF
Position: 529-548
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 45
Chemical type: Peptide from protein
Sequence: FLGKDSIRYYNKVPVEKRVF
Position: 529-548
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 48
Chemical type: Peptide from protein
Sequence: FDRLNTGILNKHLQDLMEGL
Position: 565-584
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 48
Chemical type: Peptide from protein
Sequence: FDRLNTGILNKHLQDLMEGL
Position: 565-584
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 51
Chemical type: Peptide from protein
Sequence: QLKELTAPDENIPAKILSYN
Position: 601-620
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 51
Chemical type: Peptide from protein
Sequence: QLKELTAPDENIPAKILSYN
Position: 601-620
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 52
Chemical type: Peptide from protein
Sequence: PAKILSYNRANRAVAILCNH
Position: 613-632
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative

Epitope: Peptide 52
Chemical type: Peptide from protein
Sequence: PAKILSYNRANRAVAILCNH
Position: 613-632
Source molecule (GenBank): NP_003277.1
Assay category: BCell
Result: Negative