LiteFold/IEDB huggingface dataset:
Reference: L Moiola; P Karachunski; M P Protti; J F Howard; B M Conti-Tronconi. "Epitopes on the beta subunit of human muscle acetylcholine receptor recognized by CD4+ cells of myasthenia gravis patients and healthy subjects." The Journal of clinical investigation (1994).

Epitope: hAChRß166-185
Chemical type: Peptide from protein
Sequence: TMVFSSYSYDSSEVSLQTGL
Position: 166-185
Source molecule (GenBank): NP_000738.2
Assay category: TCell
Result: Positive
Host:  27-40 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRß316-335
Chemical type: Peptide from protein
Sequence: MVLVTFSVILSVVVLNLHHR
Position: 316-335
Source molecule (GenBank): NP_000738.2
Assay category: TCell
Result: Positive
Host:  25-61 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRß316-335
Chemical type: Peptide from protein
Sequence: MVLVTFSVILSVVVLNLHHR
Position: 316-335
Source molecule (GenBank): NP_000738.2
Assay category: TCell
Result: Positive
Host:  27-40 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRß391-410
Chemical type: Peptide from protein
Sequence: FIRKPPSDFLFPKPNRFQPE
Position: 391-410
Source molecule (GenBank): NP_000738.2
Assay category: TCell
Result: Positive
Host:  25-61 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRß391-410
Chemical type: Peptide from protein
Sequence: FIRKPPSDFLFPKPNRFQPE
Position: 391-410
Source molecule (GenBank): NP_000738.2
Assay category: TCell
Result: Positive
Host:  27-40 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone
Reference: L Verdot; M Ferrer-di-Martino; B Bertin; A D Strosberg; J Hoebeke. "Production of anti-peptide antibodies directed against the first and the second extracellular loop of the human serotonin 5-HT1A receptor." Biochimie (1994).

Epitope: human serotonin 5-HTIA receptor Y16L
Chemical type: Peptide from protein
Sequence: YQVLNKWTLGQVTCDL
Position: 96-111
Source molecule (GenBank): P08908.3
Assay category: BCell
Result: Positive

Epitope: human serotonin 5-HTIA receptor Y16L
Chemical type: Peptide from protein
Sequence: YQVLNKWTLGQVTCDL
Position: 96-111
Source molecule (GenBank): P08908.3
Assay category: BCell
Result: Positive

Epitope: human serotonin 5-HTIA receptor Y16L
Chemical type: Peptide from protein
Sequence: YQVLNKWTLGQVTCDL
Position: 96-111
Source molecule (GenBank): P08908.3
Assay category: BCell
Result: Negative
Reference: S J Tzartos; C Valcana; R Kouvatsou; A Kokla. "The tyrosine phosphorylation site of the acetylcholine receptor beta subunit is located in a highly immunogenic epitope implicated in channel function: antibody probes for beta subunit phosphorylation and function." The EMBO journal (1993).

Epitope: Torpedo AChR (357-366)
Chemical type: Peptide from protein
Sequence: IRKPAGDFVC
Position: 381-390
Source molecule (GenBank): P02712.1
Assay category: BCell
Result: Positive
Reference: M Bellone; N Ostlie; P Karachunski; A A Manfredi; B M Conti-Tronconi. "Cryptic epitopes on the nicotinic acetylcholine receptor are recognized by autoreactive CD4+ cells." Journal of immunology (Baltimore, Md. : 1950) (1993).

Epitope: T alpha 181-200
Chemical type: Peptide from protein
Sequence: YRGWKHWVYYTCCPDTPYLD
Position: 205-224
Source molecule (GenBank): AAA96705.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: T alpha 181-200
Chemical type: Peptide from protein
Sequence: YRGWKHWVYYTCCPDTPYLD
Position: 205-224
Source molecule (GenBank): AAA96705.1
Assay category: TCell
Result: Positive-High
Host: F 6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: T alpha 181-200
Chemical type: Peptide from protein
Sequence: YRGWKHWVYYTCCPDTPYLD
Position: 205-224
Source molecule (GenBank): AAA96705.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Tδ 1-20
Chemical type: Peptide from protein
Sequence: VNEEERLINDLLIVNKYNKH
Position: 22-41
Source molecule (GenBank): P02718.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Tδ 46-65
Chemical type: Peptide from protein
Sequence: KETDETLTSNVWMDHAWYDH
Position: 67-86
Source molecule (GenBank): P02718.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Tδ 196-215
Chemical type: Peptide from protein
Sequence: PAKKNIYPDKFPNGTNYQDV
Position: 217-236
Source molecule (GenBank): P02718.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Tδ 211-230
Chemical type: Peptide from protein
Sequence: NYQDVTFYLIIRRKPLFYVI
Position: 232-251
Source molecule (GenBank): P02718.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo
Reference: L Moiola; M P Protti; A A Manfredi; M H Yuen; J F Howard; B M Conti-Tronconi. "T-helper epitopes on human nicotinic acetylcholine receptor in myasthenia gravis." Annals of the New York Academy of Sciences (1993).

Epitope: alpha 7-22
Chemical type: Peptide from protein
Sequence: LVAKLFKDYSSVVRPV
Position: 27-42
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Host:  25-89 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha 76-93
Chemical type: Peptide from protein
Sequence: KKIHIPSEKIWRPDLVLY
Position: 121-138
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Host:  25-89 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha 101-120
Chemical type: Peptide from protein
Sequence: AIVKFTKVLLQYTGHITWTP
Position: 146-165
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  25-89 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: alpha 101-120
Chemical type: Peptide from protein
Sequence: AIVKFTKVLLQYTGHITWTP
Position: 146-165
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  25-89 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone
Reference: M Shenoy; M Oshima; M Z Atassi; P Christadoss. "Suppression of experimental autoimmune myasthenia gravis by epitope-specific neonatal tolerance to synthetic region alpha 146-162 of acetylcholine receptor." Clinical immunology and immunopathology (1993).

Epitope: tAChR α67-82
Chemical type: Peptide from protein
Sequence: WNPADYGGIKKIRLPS
Position: 91-106
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α67-82
Chemical type: Peptide from protein
Sequence: WNPADYGGIKKIRLPS
Position: 91-106
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α89-104
Chemical type: Peptide from protein
Sequence: DLVLYNNADGDFAIVH
Position: 113-128
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α89-104
Chemical type: Peptide from protein
Sequence: DLVLYNNADGDFAIVH
Position: 113-128
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host: F 8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo
Reference: M Z Atassi; K H Ruan; K Jinnai; M Oshima; T Ashizawa. "Epitope-specific suppression of antibody response in experimental autoimmune myasthenia gravis by a monomethoxypolyethylene glycol conjugate of a myasthenogenic synthetic peptide." Proceedings of the National Academy of Sciences of the United States of America (1992).

Epitope: Torpedo AChR residues 67-82
Chemical type: Peptide from protein
Sequence: WNPADYGGIKKIRLPS
Position: 91-106
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host:  8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Torpedo AChR residues 67-82
Chemical type: Peptide from protein
Sequence: WNPADYGGIKKIRLPS
Position: 91-106
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive-Low
Host:  8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Torpedo AChR residues 89-104
Chemical type: Peptide from protein
Sequence: DLVLYNNADGDFAIVH
Position: 113-128
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive-Low
Host:  8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Torpedo AChR residues 89-104
Chemical type: Peptide from protein
Sequence: DLVLYNNADGDFAIVH
Position: 113-128
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host:  8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo
Reference: H Eng; Y Magnusson; G Matell; A K Lefvert; R Saponja; J Hoebeke. "Beta 2-adrenergic receptor antibodies in myasthenia gravis." Journal of autoimmunity (1992).

Epitope: Beta 2 AR 172-187
Chemical type: Peptide from protein
Sequence: HWYRATHQEAINCYAN
Position: 172-187
Source molecule (GenBank): AAH12481.3
Assay category: BCell
Result: Positive
Reference: T Ashizawa; K H Ruan; K Jinnai; M Z Atassi. "Profile of the regions on the alpha-chain of human acetylcholine receptor recognized by autoantibodies in myasthenia gravis." Molecular immunology (1992).

Epitope: Human AChR α56-71
Chemical type: Peptide from protein
Sequence: LKQQWVDYNLKWNPDD
Position: 76-91
Source molecule (GenBank): AAD14247.1
Assay category: BCell
Result: Positive

Epitope: Human AChR α56-71
Chemical type: Peptide from protein
Sequence: LKQQWVDYNLKWNPDD
Position: 76-91
Source molecule (GenBank): AAD14247.1
Assay category: BCell
Result: Positive

Epitope: Human AChR α56-71
Chemical type: Peptide from protein
Sequence: LKQQWVDYNLKWNPDD
Position: 76-91
Source molecule (GenBank): AAD14247.1
Assay category: BCell
Result: Positive-Low

Epitope: Human AChR α78-93
Chemical type: Peptide from protein
Sequence: IHIPSEKIWRPDLVLY
Position: 123-138
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Negative

Epitope: Human AChR α78-93
Chemical type: Peptide from protein
Sequence: IHIPSEKIWRPDLVLY
Position: 123-138
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Positive

Epitope: Human AChR α78-93
Chemical type: Peptide from protein
Sequence: IHIPSEKIWRPDLVLY
Position: 123-138
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Positive

Epitope: Human AChR α170-186
Chemical type: Peptide from protein
Sequence: FMESGEWVIKESRGWKH
Position: 215-231
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Positive

Epitope: Human AChR α170-186
Chemical type: Peptide from protein
Sequence: FMESGEWVIKESRGWKH
Position: 215-231
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Positive

Epitope: Human AChR α170-186
Chemical type: Peptide from protein
Sequence: FMESGEWVIKESRGWKH
Position: 215-231
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Positive-Low
Reference: M Bellone; N Ostlie; S Lei; A A Manfredi; B M Conti-Tronconi. "T helper function of CD4+ cells specific for defined epitopes on the acetylcholine receptor in congenic mouse strains." Journal of autoimmunity (1992).

Epitope: Tα 181-200
Chemical type: Peptide from protein
Sequence: YRGWKHWVYYTCCPDTPYLD
Position: 205-224
Source molecule (GenBank): AAA96705.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Tα 181-200
Chemical type: Peptide from protein
Sequence: YRGWKHWVYYTCCPDTPYLD
Position: 205-224
Source molecule (GenBank): AAA96705.1
Assay category: TCell
Result: Negative
Host: F 6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Tα 181-200
Chemical type: Peptide from protein
Sequence: YRGWKHWVYYTCCPDTPYLD
Position: 205-224
Source molecule (GenBank): AAA96705.1
Assay category: TCell
Result: Positive-Low
Host: F 6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Tα 181-200
Chemical type: Peptide from protein
Sequence: YRGWKHWVYYTCCPDTPYLD
Position: 205-224
Source molecule (GenBank): AAA96705.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo
Reference: M Sano; D J McCormick; S Talib; G E Griesmann; V A Lennon. "Identification of three extended antibody-binding segments in recombinant human muscle acetylcholine receptor alpha subunit extracellular domain 1-210." International immunology (1991).

Epitope: Human AChRα 33-48
Chemical type: Peptide from protein
Sequence: VGLQLIQLINVDEVNQ
Position: 53-68
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Negative
Host: F 11 weeks

Epitope: Human AChRα 33-48
Chemical type: Peptide from protein
Sequence: VGLQLIQLINVDEVNQ
Position: 53-68
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Negative

Epitope: Human AChRα 33-48
Chemical type: Peptide from protein
Sequence: VGLQLIQLINVDEVNQ
Position: 53-68
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Negative
Host: F 20 weeks

Epitope: Human AChRα 49-64
Chemical type: Peptide from protein
Sequence: IVTTNVRLKQQWVDYN
Position: 69-84
Source molecule (GenBank): AAD14247.1
Assay category: BCell
Result: Negative
Host: F 11 weeks

Epitope: Human AChRα 49-64
Chemical type: Peptide from protein
Sequence: IVTTNVRLKQQWVDYN
Position: 69-84
Source molecule (GenBank): AAD14247.1
Assay category: BCell
Result: Negative

Epitope: Human AChRα 49-64
Chemical type: Peptide from protein
Sequence: IVTTNVRLKQQWVDYN
Position: 69-84
Source molecule (GenBank): AAD14247.1
Assay category: BCell
Result: Negative
Host: F 20 weeks

Epitope: Human AChRα 105-120
Chemical type: Peptide from protein
Sequence: FTKVLLQYTGHITWTP
Position: 150-165
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Negative
Host: F 11 weeks

Epitope: Human AChRα 105-120
Chemical type: Peptide from protein
Sequence: FTKVLLQYTGHITWTP
Position: 150-165
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Negative

Epitope: Human AChRα 105-120
Chemical type: Peptide from protein
Sequence: FTKVLLQYTGHITWTP
Position: 150-165
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Negative
Host: F 20 weeks

Epitope: Human AChRα 129-144
Chemical type: Peptide from protein
Sequence: EIIVTHFPFDEQNCSM
Position: 174-189
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Negative

Epitope: Human AChRα 129-144
Chemical type: Peptide from protein
Sequence: EIIVTHFPFDEQNCSM
Position: 174-189
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Negative
Host: F 20 weeks

Epitope: Human AChRα 129-144
Chemical type: Peptide from protein
Sequence: EIIVTHFPFDEQNCSM
Position: 174-189
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Negative
Host: F 11 weeks

Epitope: Human AChRα 137-152
Chemical type: Peptide from protein
Sequence: FDEQNCSMKLGTWTYD
Position: 182-197
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Negative

Epitope: Human AChRα 137-152
Chemical type: Peptide from protein
Sequence: FDEQNCSMKLGTWTYD
Position: 182-197
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Positive
Host: F 20 weeks

Epitope: Human AChRα 137-152
Chemical type: Peptide from protein
Sequence: FDEQNCSMKLGTWTYD
Position: 182-197
Source molecule (GenBank): P02708.2
Assay category: BCell
Result: Negative
Host: F 11 weeks
Reference: M P Protti; A A Manfredi; X D Wu; L Moiola; J F Howard; B M Conti-Tronconi. "Myasthenia gravis. T epitopes on the delta subunit of human muscle acetylcholine receptor." Journal of immunology (Baltimore, Md. : 1950) (1991).

Epitope: hAChR delta 1-20
Chemical type: Peptide from protein
Sequence: LNEEERLIRHLFQEKGYNKE
Position: 22-41
Source molecule (GenBank): NP_000742.1
Assay category: TCell
Result: Positive
Host:  33-87
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChR delta 61-80
Chemical type: Peptide from protein
Sequence: GWTDNRLKWNAEEFGNISVL
Position: 82-101
Source molecule (GenBank): NP_000742.1
Assay category: TCell
Result: Positive
Host:  33-87
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChR delta 196-215
Chemical type: Peptide from protein
Sequence: RVNVDPRAPLDSPSRQDI
Position: 219-236
Source molecule (GenBank): NP_000742.1
Assay category: TCell
Result: Positive
Host:  33-87
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChR delta 256-275
Chemical type: Peptide from protein
Sequence: EKTSVAISVLLAQSVFLLLIS
Position: 276-296
Source molecule (GenBank): NP_000742.1
Assay category: TCell
Result: Negative
Host:  33-87
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChR delta 346-362
Chemical type: Peptide from protein
Sequence: DGPSPGALVRRSSSLGY
Position: 367-383
Source molecule (GenBank): NP_000742.1
Assay category: TCell
Result: Negative
Host:  33-87
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone
Reference: M P Protti; A A Manfredi; C Straub; J F Howard; B M Conti-Tronconi. "Immunodominant regions for T helper-cell sensitization on the human nicotinic receptor alpha subunit in myasthenia gravis." Proceedings of the National Academy of Sciences of the United States of America (1990).

Epitope: hAChRα7-22
Chemical type: Peptide from protein
Sequence: LVAKLFKDYSSVVRPV
Position: 27-42
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: hAChRα76-93
Chemical type: Peptide from protein
Sequence: KKIHIPSEKIWRPDLVLY
Position: 121-138
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone
Reference: M P Protti; A A Manfredi; C Straub; J F Howard; B M Conti-Tronconi. "CD4+ T cell response to the human acetylcholine receptor alpha subunit in myasthenia gravis. A study with synthetic peptides." Journal of immunology (Baltimore, Md. : 1950) (1990).

Epitope: Human AChR alpha residues 7-22
Chemical type: Peptide from protein
Sequence: LVAKLFKDYSSVVRPV
Position: 27-42
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 7-22
Chemical type: Peptide from protein
Sequence: LVAKLFKDYSSVVRPV
Position: 27-42
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 101-120
Chemical type: Peptide from protein
Sequence: AIVKFTKVLLQYTGHITWTP
Position: 121-140
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Host:  23-78 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Human AChR alpha residues 101-120
Chemical type: Peptide from protein
Sequence: AIVKFTKVLLQYTGHITWTP
Position: 121-140
Source molecule (GenBank): AAD14247.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: M P Protti; A A Manfredi; C Straub; X D Wu; J F Howard; B M Conti-Tronconi. "Use of synthetic peptides to establish anti-human acetylcholine receptor CD4+ cell lines from myasthenia gravis patients." Journal of immunology (Baltimore, Md. : 1950) (1990).

Epitope: Hα 76-93
Chemical type: Peptide from protein
Sequence: KKIHIPSEKIWRPDLVLY
Position: 121-138
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
MHC allele types: 235 241 300 339 350
Host: F 72 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Hα 101-120
Chemical type: Peptide from protein
Sequence: AIVKFTKVLLQYTGHITWTP
Position: 146-165
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
MHC allele types: 235 241 300 339 350
Host: F 72 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Hα 7-22
Chemical type: Peptide from protein
Sequence: LVAKLFKDYSSVVRPV
Position: 27-42
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
MHC allele types: 235 241 300 339 350
Host: F 72 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone
Reference: G C Harcourt; N Sommer; J Rothbard; H N Willcox; J Newsom-Davis. "A juxta-membrane epitope on the human acetylcholine receptor recognized by T cells in myasthenia gravis." The Journal of clinical investigation (1988).

Epitope: AChR 99-116
Chemical type: Peptide from protein
Sequence: DFAIVKFTKVLLQYTGHI
Position: 144-161
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR 99-116
Chemical type: Peptide from protein
Sequence: DFAIVKFTKVLLQYTGHI
Position: 144-161
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR 99-116
Chemical type: Peptide from protein
Sequence: DFAIVKFTKVLLQYTGHI
Position: 144-161
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: M Ratnam; P B Sargent; V Sarin; J L Fox; D L Nguyen; J Rivier; M Criado; J Lindstrom. "Location of antigenic determinants on primary sequences of subunits of nicotinic acetylcholine receptor by peptide mapping." Biochemistry (1986).

Epitope: AChR alpha (235-242)
Chemical type: Peptide from protein
Sequence: LPTDSGEK
Position: 259-266
Source molecule (GenBank): P02710.1
Assay category: BCell
Result: Positive
Host: F
Reference: M Oshima; M Z Atassi. "T cells of mice treated with mPEG-myasthenogenic peptide conjugate are involved in protection against EAMG by stimulating lower pathogenic antibody responses." Autoimmunity (2000).

Epitope: tAChR α67-82
Chemical type: Peptide from protein
Sequence: WNPADYGGIKKIRLPS
Position: 91-106
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host:  8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α67-82
Chemical type: Peptide from protein
Sequence: WNPADYGGIKKIRLPS
Position: 91-106
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host:  8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α89-104
Chemical type: Peptide from protein
Sequence: DLVLYNNADGDFAIVH
Position: 113-128
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Negative
Host:  8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: tAChR α89-104
Chemical type: Peptide from protein
Sequence: DLVLYNNADGDFAIVH
Position: 113-128
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host:  8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo