LiteFold/IEDB huggingface dataset:
Reference: Jessica R Harmon; Dominique J Barbeau; Stuart T Nichol; Christina F Spiropoulou; Anita K McElroy. "Rift Valley fever virus vaccination induces long-lived, antigen-specific human T cell responses." NPJ vaccines (2020).

Epitope: Gn353
Chemical type: Peptide from protein
Sequence: ITKCEPHGLVVRSTG
Position: 456-470
Source molecule (GenBank): 1211069864
Assay category: TCell
Result: Positive
Host:  37-61 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Gn553
Chemical type: Peptide from protein
Sequence: LIVSYASACSELIQA
Position: 656-670
Source molecule (GenBank): 1211069864
Assay category: TCell
Result: Positive
Host:  37-61 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Gc425
Chemical type: Peptide from protein
Sequence: IAIDPFDDRREAGGE
Position: 1088-1102
Source molecule (GenBank): 1211069864
Assay category: TCell
Result: Positive
Host:  37-61 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Gc485
Chemical type: Peptide from protein
Sequence: FLLIYLGRTGLSKMW
Position: 1148-1162
Source molecule (GenBank): 1211069864
Assay category: TCell
Result: Positive
Host:  37-61 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: Gonzalo R Acevedo; Natalia A Juiz; Andrea Ziblat; Lucas Pérez Perri; Magalí C Girard; Micaela S Ossowski; Marisa Fernández; Yolanda Hernández; Raúl Chadi; Michael Wittig; Andre Franke; Morten Nielsen; Karina A Gómez. "In Silico Guided Discovery of Novel Class I and II  Epitopes Recognized by T Cells from Chagas' Disease Patients." Journal of immunology (Baltimore, Md. : 1950) (2020).

Epitope: Epitope 1
Chemical type: Peptide from protein
Sequence: VTVTNVFLYNRPLSV
Position: 674-688
Source molecule (GenBank): 1393599283
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 8
Chemical type: Peptide from protein
Sequence: FLARLHAAANPHATF
Position: 67-81
Source molecule (GenBank): 118157
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 9
Chemical type: Peptide from protein
Sequence: TVKNVFLYNRPLNST
Position: 672-686
Source molecule (GenBank): 1393604114
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 22
Chemical type: Peptide from protein
Sequence: LYHFANYNFTLVATV
Position: 532-546
Source molecule (GenBank): 3298145
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Epitope 39
Chemical type: Peptide from protein
Sequence: HQEYLEAFRRLYKTL
Position: 440-454
Source molecule (GenBank): 1393615668
Assay category: TCell
Result: Negative
Host:  adult
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: Sangita Khatri; Jonas Hansen; Kira Astakhova. "Antibodies to synthetic citrullinated peptide epitope correlate with disease activity and flares in rheumatoid arthritis." PloS one (2020).

Epitope: Fib 210-225 E6
Chemical type: Peptide from protein
Sequence: KDLLPSRDRQHLPLIK
Position: 210-225
Source molecule (GenBank): P02671.2
Assay category: BCell
Result: Positive
Host:  28-56 years

Epitope: Vim 2-17 E9
Chemical type: Peptide from protein
Sequence: STRSVSSSSYRRMFGG
Position: 2-17
Source molecule (GenBank): P08670.4
Assay category: BCell
Result: Positive
Host:  28-56 years
Reference: Liping Huang; Zhenzhao Sun; Deli Xia; Yanwu Wei; Encheng Sun; Chunguo Liu; Hongzhen Zhu; Haiqiao Bian; Hongli Wu; Li Feng; Jingfei Wang; Changming Liu. "Neutralization Mechanism of a Monoclonal Antibody Targeting a Porcine Circovirus Type 2 Cap Protein Conformational Epitope." Journal of virology (2020).

Epitope: MAb 3A5 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: Y55, T56, V57, K58, A59, T60, T61, V62, A68, V69, D70, N128, T131, K132, A133, T134, A135, L136, T137, N204
Source molecule (GenBank): ACE78292.1
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: MAb 3A5 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: Y55, T56, V57, K58, A59, T60, T61, V62, A68, V69, D70, N128, T131, K132, A133, T134, A135, L136, T137, N204
Source molecule (GenBank): ACE78292.1
Assay category: BCell
Result: Positive
Host: F 6 weeks

Epitope: MAb 3A5 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: Y55, T56, V57, K58, A59, T60, T61, V62, A68, V69, D70, N128, T131, K132, A133, T134, A135, L136, T137, N204
Source molecule (GenBank): ACE78292.1
Assay category: BCell
Result: Positive
Host: F 6 weeks
Reference: Xianwei Wang; Linlin Fang; Jing Zhan; Xiaoli Shi; Qianyu Liu; Qianqian Lu; Juan Bai; Yufeng Li; Ping Jiang. "Identification and characterization of linear B cell epitopes on the nucleocapsid protein of porcine epidemic diarrhea virus using monoclonal antibodies." Virus research (2020).

Epitope: Polypeptide III
Chemical type: Peptide from protein
Sequence: EEAIYDDVGAPS
Position: 399-410
Source molecule (GenBank): Q07499.1
Assay category: BCell
Result: Positive-Low
Host:  8 weeks
Reference: Hok Yee Chan; Jiajia Zhang; Caroline C Garliss; Abena K Kwaa; Joel N Blankson; Kellie N Smith. "A T Cell Receptor Sequencing-Based Assay Identifies Cross-Reactive Recall CD8<sup>+</sup> T Cell Clonotypes Against Autologous HIV-1 Epitope Variants." Frontiers in immunology (2020).

Epitope: GAG TW10 (240-249) autologous variant
Chemical type: Peptide from protein
Sequence: TSTLAEQVAW
Position: 242-251
Source molecule (GenBank): ADD25374.1
Assay category: TCell
Result: Positive
MHC allele types: 268 737 235 242
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GAG TW10 (240-249) autologous variant
Chemical type: Peptide from protein
Sequence: TSTLSEQVAW
Position: 237-246
Source molecule (GenBank): AOZ18404.1
Assay category: TCell
Result: Positive
MHC allele types: 268 737 235 242
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: Yoko Shima; Daisuke Morita; Tatsuaki Mizutani; Naoki Mori; Bunzo Mikami; Masahiko Sugita. "Crystal structures of lysophospholipid-bound MHC class I molecules." The Journal of biological chemistry (2020).

Epitope: Lyso-PC 16:0
Chemical type: Other Non-Sequence
Assay category: MhcLigandElution
Result: Positive

Epitope: Lyso-PC 16:0
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Negative

Epitope: Lyso-PC 16:0
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.15

Epitope: Lyso-PC 16:0
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.87

Epitope: Lyso-PC 16:0
Chemical type: Other Non-Sequence
Assay category: MhcBinding
Result: Positive
Reference: Janine D Brunner; Roman P Jakob; Tobias Schulze; Yvonne Neldner; Anna Moroni; Gerhard Thiel; Timm Maier; Stephan Schenck. "Structural basis for ion selectivity in TMEM175 K<sup>+</sup> channels." eLife (2020).

Epitope: Epitope of nanobody Nb51H01 on MtTMEM175 channel
Chemical type: Discontinuous protein residues
Discontinuous residues: K169, K171, S172, L173, D175, L176, N177, S178, Y179, I181
Source molecule (GenBank): WP_013454588.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.9

Epitope: Epitope of nanobody Nb51H01 on MtTMEM175 channel
Chemical type: Discontinuous protein residues
Discontinuous residues: K169, K171, S172, L173, D175, L176, N177, S178, Y179, I181
Source molecule (GenBank): WP_013454588.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.4

Epitope: Epitope of nanobody Nb51H01 on MtTMEM175 channel
Chemical type: Discontinuous protein residues
Discontinuous residues: K169, K171, S172, L173, D175, L176, N177, S178, Y179, I181
Source molecule (GenBank): WP_013454588.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nb51H01 on MtTMEM175 channel
Chemical type: Discontinuous protein residues
Discontinuous residues: K169, K171, S172, L173, D175, L176, N177, S178, Y179, I181
Source molecule (GenBank): WP_013454588.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.2

Epitope: Epitope of nanobody Nb51H01 on MtTMEM175 channel
Chemical type: Discontinuous protein residues
Discontinuous residues: K169, K171, S172, L173, D175, L176, N177, S178, Y179, I181
Source molecule (GenBank): WP_013454588.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.4

Epitope: Epitope of nanobody Nb51H01 on MtTMEM175 channel
Chemical type: Discontinuous protein residues
Discontinuous residues: K169, K171, S172, L173, D175, L176, N177, S178, Y179, I181
Source molecule (GenBank): WP_013454588.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.5

Epitope: Epitope of nanobody Nb51H01 on MtTMEM175 channel
Chemical type: Discontinuous protein residues
Discontinuous residues: K169, K171, S172, L173, D175, L176, N177, S178, Y179, I181
Source molecule (GenBank): WP_013454588.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.8
Reference: Emmi-Leena Ihantola; Henna Ilmonen; Anssi Kailaanmäki; Marja Rytkönen-Nissinen; Aurélien Azam; Bernard Maillère; Cecilia S Lindestam Arlehamn; Alessandro Sette; Keshav Motwani; Howard R Seay; Todd M Brusko; Mikael Knip; Riitta Veijola; Jorma Toppari; Jorma Ilonen; Tuure Kinnunen. "Characterization of Proinsulin T Cell Epitopes Restricted by Type 1 Diabetes-Associated HLA Class II Molecules." Journal of immunology (Baltimore, Md. : 1950) (2020).

Epitope: C22-A1
Chemical type: Peptide from protein
Sequence: SLQPLALEGSLQKRG
Position: 76-90
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 3600.0

Epitope: C22-A1
Chemical type: Peptide from protein
Sequence: SLQPLALEGSLQKRG
Position: 76-90
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 90.0

Epitope: C22-A1
Chemical type: Peptide from protein
Sequence: SLQPLALEGSLQKRG
Position: 76-90
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 63000.0

Epitope: C22-A1
Chemical type: Peptide from protein
Sequence: SLQPLALEGSLQKRG
Position: 76-90
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 70000.0

Epitope: C22-A1
Chemical type: Peptide from protein
Sequence: SLQPLALEGSLQKRG
Position: 76-90
Source molecule (GenBank): P01308.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 104390.0

Epitope: C23-35
Chemical type: Peptide from protein
Sequence: LQPLALEGSLQKR
Position: 77-89
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: C23-35
Chemical type: Peptide from protein
Sequence: LQPLALEGSLQKR
Position: 77-89
Source molecule (GenBank): P01308.1
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone
Reference: Erwan Atcheson; Wenqin Li; Carly M Bliss; Senthil Chinnakannan; Kathrin Heim; Hannah Sharpe; Claire Hutchings; Isabelle Dietrich; Dung Nguyen; Amit Kapoor; Michael A Jarvis; Paul Klenerman; Eleanor Barnes; Peter Simmonds. "Use of an Outbred Rat Hepacivirus Challenge Model for Design and Evaluation of Efficacy of Different Immunization Strategies for Hepatitis C Virus." Hepatology (Baltimore, Md.) (2020).

Epitope: NS4b-V2A mutant
Chemical type: Peptide from protein
Sequence: MAGHVLLTY
Assay category: TCell
Result: Positive-Low
Host: M 
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo
Reference: Alex S Hartlage; Christopher M Walker; Amit Kapoor. "Priming of Antiviral CD8 T Cells without Effector Function by a Persistently Replicating Hepatitis C-Like Virus." Journal of virology (2020).

Epitope: NS3 1446–1463
Chemical type: Peptide from protein
Sequence: PAEVATHLSFYHNQVGLP
Position: 1446-1463
Source molecule (GenBank): AQV09561.1
Assay category: TCell
Result: Negative
Host: F 7-10 weeks
Cell type: T cell CD4+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: NS3 1446–1463
Chemical type: Peptide from protein
Sequence: PAEVATHLSFYHNQVGLP
Position: 1446-1463
Source molecule (GenBank): AQV09561.1
Assay category: TCell
Result: Negative
Host: F 7-10 weeks
Cell type: T cell CD4+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: NS3 1446–1463
Chemical type: Peptide from protein
Sequence: PAEVATHLSFYHNQVGLP
Position: 1446-1463
Source molecule (GenBank): AQV09561.1
Assay category: TCell
Result: Negative
Host: F 7-10 weeks
Cell type: T cell CD4+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: NS3 1446–1463
Chemical type: Peptide from protein
Sequence: PAEVATHLSFYHNQVGLP
Position: 1446-1463
Source molecule (GenBank): AQV09561.1
Assay category: TCell
Result: Negative
Host: F 7-10 weeks
Cell type: T cell CD4+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: NS3 1446–1463
Chemical type: Peptide from protein
Sequence: PAEVATHLSFYHNQVGLP
Position: 1446-1463
Source molecule (GenBank): AQV09561.1
Assay category: TCell
Result: Negative
Host: F 7-10 weeks
Cell type: T cell CD4+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: NS3 1446–1463
Chemical type: Peptide from protein
Sequence: PAEVATHLSFYHNQVGLP
Position: 1446-1463
Source molecule (GenBank): AQV09561.1
Assay category: TCell
Result: Negative
Host: F 7-10 weeks
Cell type: T cell CD4+
Tissue: liver
Culture conditions: Direct Ex Vivo
Reference: Cheryl Yi-Pin Lee; Guillaume Carissimo; Zheyuan Chen; Fok-Moon Lum; Farhana Abu Bakar; Ravisankar Rajarethinam; Teck-Hui Teo; Anthony Torres-Ruesta; Laurent Renia; Lisa Fp Ng. "Type I interferon shapes the quantity and quality of the anti-Zika virus antibody response." Clinical & translational immunology (2020).

Epitope: E P6
Chemical type: Peptide from protein
Sequence: KKMTGKSIQPENLEYRIM
Position: 413-430
Source molecule (GenBank): AHZ13508.1
Assay category: BCell
Result: Positive-High
Host:  4 weeks

Epitope: E P6
Chemical type: Peptide from protein
Sequence: KKMTGKSIQPENLEYRIM
Position: 413-430
Source molecule (GenBank): AHZ13508.1
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: E P17
Chemical type: Peptide from protein
Sequence: SLCTAAFTFTKIPA
Position: 596-609
Source molecule (GenBank): AHZ13508.1
Assay category: BCell
Result: Positive-Low
Host:  4 weeks

Epitope: NS1 P23
Chemical type: Peptide from protein
Sequence: DVGCSVDFSKKETRCGTG
Position: 795-812
Source molecule (GenBank): AHZ13508.1
Assay category: BCell
Result: Positive-Low
Host:  4 weeks

Epitope: NS1 P32
Chemical type: Peptide from protein
Sequence: AGPLSHHNTREGYRTQMK
Position: 1042-1059
Source molecule (GenBank): AHZ13508.1
Assay category: BCell
Result: Positive
Host:  4 weeks

Epitope: NS1 P36
Chemical type: Peptide from protein
Sequence: KVHVEETCGTRGPSLRST
Position: 1078-1095
Source molecule (GenBank): AHZ13508.1
Assay category: BCell
Result: Positive-High
Host:  4 weeks
Reference: Goran Bajic; Max J Maron; Timothy M Caradonna; Ming Tian; Adam Mermelstein; Daniela Fera; Garnett Kelsoe; Masayuki Kuraoka; Aaron G Schmidt. "Structure-Guided Molecular Grafting of a Complex Broadly Neutralizing Viral Epitope." ACS infectious diseases (2020).

Epitope: Epitope of K03.12 on the Influenza A HA1 RBS
Chemical type: Discontinuous protein residues
Discontinuous residues: Y108, G147, V148, S149, A150, W166, T168, K170, N171, L173, P199, D203, L207, Q239
Source molecule (GenBank): ABU99109.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.0
Host: F 39 years

Epitope: Epitope of K03.12 on the Influenza A HA1 RBS
Chemical type: Discontinuous protein residues
Discontinuous residues: Y108, G147, V148, S149, A150, W166, T168, K170, N171, L173, P199, D203, L207, Q239
Source molecule (GenBank): ABU99109.1
Assay category: BCell
Result: Positive
Quantitative measurement: 830.0
Host: F 39 years
Reference: Christopher J Holland; Rory M Crean; Johanne M Pentier; Ben de Wet; Angharad Lloyd; Velupillai Srikannathasan; Nikolai Lissin; Katy A Lloyd; Thomas H Blicher; Paul J Conroy; Miriam Hock; Robert J Pengelly; Thomas E Spinner; Brian Cameron; Elizabeth A Potter; Anitha Jeyanthan; Peter E Molloy; Malkit Sami; Milos Aleksic; Nathaniel Liddy; Ross A Robinson; Stephen Harper; Marco Lepore; Chris R Pudney; Marc W van der Kamp; Pierre J Rizkallah; Bent K Jakobsen; Annelise Vuidepot; David K Cole. "Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA." The Journal of clinical investigation (2020).

Epitope: WT1 (126-134)
Chemical type: Peptide from protein
Sequence: RMFPNAPYL
Position: 126-134
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive
Quantitative measurement: 2.95

Epitope: WT1 (126-134)
Chemical type: Peptide from protein
Sequence: RMFPNAPYL
Position: 126-134
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive
Quantitative measurement: 86000.0

Epitope: WT1 (126-134)
Chemical type: Peptide from protein
Sequence: RMFPNAPYL
Position: 126-134
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive
Quantitative measurement: 0.0011

Epitope: WT1 (126-134)
Chemical type: Peptide from protein
Sequence: RMFPNAPYL
Position: 126-134
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive
Quantitative measurement: 360000.0

Epitope: WT1 (126-134)
Chemical type: Peptide from protein
Sequence: RMFPNAPYL
Position: 126-134
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive
Quantitative measurement: 0.00028

Epitope: WT1 (126-134)
Chemical type: Peptide from protein
Sequence: RMFPNAPYL
Position: 126-134
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive
Quantitative measurement: 13.0

Epitope: WT1 (126-134)
Chemical type: Peptide from protein
Sequence: RMFPNAPYL
Position: 126-134
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive
Quantitative measurement: 260000.0

Epitope: WT1 (126-134)
Chemical type: Peptide from protein
Sequence: RMFPNAPYL
Position: 126-134
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive
Quantitative measurement: 0.018

Epitope: WT1 (126-134)
Chemical type: Peptide from protein
Sequence: RMFPNAPYL
Position: 126-134
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive
Quantitative measurement: 0.76

Epitope: WT1 (126-134)
Chemical type: Peptide from protein
Sequence: RMFPNAPYL
Position: 126-134
Source molecule (GenBank): P19544.2
Assay category: TCell
Result: Positive
Quantitative measurement: 70.0

Epitope: WT1 (126-134)
Chemical type: Peptide from protein
Sequence: RMFPNAPYL
Position: 126-134
Source molecule (GenBank): P19544.2
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.95
Reference: Yi-Lynn Liang; Matthew J Belousoff; Madeleine M Fletcher; Xin Zhang; Maryam Khoshouei; Giuseppe Deganutti; Cassandra Koole; Sebastian G B Furness; Laurence J Miller; Debbie L Hay; Arthur Christopoulos; Christopher A Reynolds; Radostin Danev; Denise Wootten; Patrick M Sexton. "Structure and Dynamics of Adrenomedullin Receptors AM<sub>1</sub> and AM<sub>2</sub> Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins." ACS pharmacology & translational science (2020).

Epitope: Epitope of nanobody Nb35 on G protein heterotrimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R228, D229, E230, R231, R232, Q262, T263, N264, Q267, K271, L272, S275, I276, N278, N279, D310, Y311, P313, E314, D354; B: R8, K15, T184, C204, D205, A206, E226, S227, D228, D246
Source molecule (GenBank): P63092.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nb35 on G protein heterotrimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R228, D229, E230, R231, R232, Q262, T263, N264, Q267, K271, L272, S275, I276, N278, N279, D310, Y311, P313, E314, D354; B: R8, K15, T184, C204, D205, A206, E226, S227, D228, D246
Source molecule (GenBank): P63092.1
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody Nb35 on G protein heterotrimer
Chemical type: Region on multi-chain protein
Discontinuous residues: A: R228, D229, E230, R231, R232, Q262, T263, N264, Q267, K271, L272, S275, I276, N278, N279, D310, Y311, P313, E314, D354; B: R8, K15, T184, C204, D205, A206, E226, S227, D228, D246
Source molecule (GenBank): P63092.1
Assay category: BCell
Result: Positive
Reference: Yanpeng Li; Dongmei Tong; Peibin Liang; Erik Lönnblom; Johan Viljanen; Bingze Xu; Kutty Selva Nandakumar; Rikard Holmdahl. "Cartilage-binding antibodies initiate joint inflammation and promote chronic erosive arthritis." Arthritis research & therapy (2020).

Epitope: CII_T_C1_R-R
Chemical type: Peptide from protein
Sequence: DPGRPGEPGLPGARGLTGRPGDA
Position: 479-501
Source molecule (GenBank): P05539.2
Assay category: BCell
Result: Positive
Host: M 12-16 weeks

Epitope: CII_T_F4_R-R
Chemical type: Peptide from protein
Sequence: GDKGEAGEPGERGLKGHRGFTGLQ
Position: 1048-1071
Source molecule (GenBank): P05539.2
Assay category: BCell
Result: Positive
Host: M 12-16 weeks
Reference: Shota Yoshida; Hironori Nakagami; Hiroki Hayashi; Yuka Ikeda; Jiao Sun; Akiko Tenma; Hideki Tomioka; Tomohiro Kawano; Munehisa Shimamura; Ryuichi Morishita; Hiromi Rakugi. "The CD153 vaccine is a senotherapeutic option for preventing the accumulation of senescent T cells in mice." Nature communications (2020).

Epitope: peptide #C
Chemical type: Peptide from protein
Sequence: KKSWAYLQ
Position: 101-108
Source molecule (GenBank): NP_033429.1
Assay category: BCell
Result: Positive-Low
Host: M 7 weeks

Epitope: peptide #E
Chemical type: Peptide from protein
Sequence: LYSSSD
Position: 234-239
Source molecule (GenBank): NP_033429.1
Assay category: BCell
Result: Positive
Host: M 7 weeks
Reference: Katarzyna Pacyga; Agnieszka Razim; Gayane Martirosian; Małgorzata Aptekorz; Andrzej Szuba; Andrzej Gamian; Andrzej Myc; Sabina Górska. "The Bioinformatic and In Vitro Studies of Clostridioides Difficile Aminopeptidase M24 Revealed the Immunoreactive KKGIK Peptide." Cells (2020).

Epitope: P7
Chemical type: Peptide from protein
Sequence: LDVKYCGESFSSKLAR
Position: 161-176
Source molecule (GenBank): WP_009893549.1
Assay category: BCell
Result: Negative

Epitope: P10
Chemical type: Peptide from protein
Sequence: GGDVKYNPVVLSYAVI
Position: 205-220
Source molecule (GenBank): WP_009893549.1
Assay category: BCell
Result: Negative

Epitope: P13
Chemical type: Peptide from protein
Sequence: FMYWLKKNVGKMEITE
Position: 325-340
Source molecule (GenBank): WP_009893549.1
Assay category: BCell
Result: Negative
Reference: Johanna E Huber; Julia Ahlfeld; Magdalena K Scheck; Magdalena Zaucha; Klaus Witter; Lisa Lehmann; Hadi Karimzadeh; Michael Pritsch; Michael Hoelscher; Frank von Sonnenburg; Andrea Dick; Giovanna Barba-Spaeth; Anne B Krug; Simon Rothenfußer; Dirk Baumjohann. "Dynamic changes in circulating T follicular helper cell composition predict neutralising antibody responses after yellow fever vaccination." Clinical & translational immunology (2020).

Epitope: NS3 49-65
Chemical type: Peptide from protein
Sequence: HTMWHVTRGAFLVRNGK
Position: 1533-1549
Source molecule (GenBank): AAT12476.1
Assay category: TCell
Result: Positive
Host:  18-38 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo