Reference: Cansu Cimen Bozkus; Vladimir Roudko; John P Finnigan; John Mascarenhas; Ronald Hoffman; Camelia Iancu-Rubin; Nina Bhardwaj. "Immune Checkpoint Blockade Enhances Shared Neoantigen-Induced T-cell Immunity Directed against Mutated Calreticulin in Myeloproliferative Neoplasms." Cancer discovery (2019).

Epitope: CALR Mut C OLP 2
Chemical type: Peptide from protein
Sequence: MRRTRRKMRRKMSPA
Position: 35-49
Source molecule (GenBank): CRH09108.1
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 143 544 27 270 1 798
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CALR Mut C OLP 2
Chemical type: Peptide from protein
Sequence: MRRTRRKMRRKMSPA
Position: 35-49
Source molecule (GenBank): CRH09108.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CALR Mut C OLP 4
Chemical type: Peptide from protein
Sequence: RRKMSPARPRTSCRE
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 203 218 23 270 1 798
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CALR Mut C OLP 4
Chemical type: Peptide from protein
Sequence: RRKMSPARPRTSCRE
Assay category: TCell
Result: Positive-Intermediate
MHC allele types: 64 425 361 363 94 774 318 587 18 68 69
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CALR Mut C P9.17
Chemical type: Peptide from protein
Sequence: RTRRKMRRK
Position: 37-45
Source molecule (GenBank): CRH09108.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CALR Mut C P9.17
Chemical type: Peptide from protein
Sequence: RTRRKMRRK
Position: 37-45
Source molecule (GenBank): CRH09108.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CALR Mut C P9.17
Chemical type: Peptide from protein
Sequence: RTRRKMRRK
Position: 37-45
Source molecule (GenBank): CRH09108.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CALR Mut C P9.17
Chemical type: Peptide from protein
Sequence: RTRRKMRRK
Position: 37-45
Source molecule (GenBank): CRH09108.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CALR Mut C P9.25
Chemical type: Peptide from protein
Sequence: KMSPARPRT
Position: 45-53
Source molecule (GenBank): CRH09108.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CALR Mut C P9.25
Chemical type: Peptide from protein
Sequence: KMSPARPRT
Position: 45-53
Source molecule (GenBank): CRH09108.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CALR Mut C P9.25
Chemical type: Peptide from protein
Sequence: KMSPARPRT
Position: 45-53
Source molecule (GenBank): CRH09108.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CALR Mut C P9.25
Chemical type: Peptide from protein
Sequence: KMSPARPRT
Position: 45-53
Source molecule (GenBank): CRH09108.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CALR Mut C P9.27
Chemical type: Peptide from protein
Sequence: SPARPRTSC
Position: 47-55
Source molecule (GenBank): CRH09108.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CALR Mut C P9.27
Chemical type: Peptide from protein
Sequence: SPARPRTSC
Position: 47-55
Source molecule (GenBank): CRH09108.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CALR Mut C P9.27
Chemical type: Peptide from protein
Sequence: SPARPRTSC
Position: 47-55
Source molecule (GenBank): CRH09108.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CALR Mut C P9.27
Chemical type: Peptide from protein
Sequence: SPARPRTSC
Position: 47-55
Source molecule (GenBank): CRH09108.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated