Reference: Christine Jung; Christina Stoeckle; Karl-Heinz Wiesmüller; Rüdiger Laub; Frank Emmrich; Günther Jung; Arthur Melms. "Complementary strategies to elucidate T helper cell epitopes in myasthenia gravis." Journal of neuroimmunology (2008).

Epitope: AChR epsilon (16-30)
Chemical type: Peptide from protein
Sequence: DPGSRPVREPEDTVT
Position: 36-50
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (16-30)
Chemical type: Peptide from protein
Sequence: DPGSRPVREPEDTVT
Position: 36-50
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (16-30)
Chemical type: Peptide from protein
Sequence: DPGSRPVREPEDTVT
Position: 36-50
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: AChR epsilon (56-70)
Chemical type: Peptide from protein
Sequence: IGIDWQDYRLNYSKD
Position: 76-90
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (56-70)
Chemical type: Peptide from protein
Sequence: IGIDWQDYRLNYSKD
Position: 76-90
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (56-70)
Chemical type: Peptide from protein
Sequence: IGIDWQDYRLNYSKD
Position: 76-90
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-High

Epitope: AChR epsilon (96-110)
Chemical type: Peptide from protein
Sequence: IDGQFGVAYDANVLV
Position: 116-130
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (96-110)
Chemical type: Peptide from protein
Sequence: IDGQFGVAYDANVLV
Position: 116-130
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (96-110)
Chemical type: Peptide from protein
Sequence: IDGQFGVAYDANVLV
Position: 116-130
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-High

Epitope: AChR epsilon (151-165)
Chemical type: Peptide from protein
Sequence: YNAEEVEFTFAVDND
Position: 171-185
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (151-165)
Chemical type: Peptide from protein
Sequence: YNAEEVEFTFAVDND
Position: 171-185
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (151-165)
Chemical type: Peptide from protein
Sequence: YNAEEVEFTFAVDND
Position: 171-185
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (161-175)
Chemical type: Peptide from protein
Sequence: AVDNDGKTINKIDID
Position: 181-195
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (161-175)
Chemical type: Peptide from protein
Sequence: AVDNDGKTINKIDID
Position: 181-195
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (161-175)
Chemical type: Peptide from protein
Sequence: AVDNDGKTINKIDID
Position: 181-195
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Negative

Epitope: AChR epsilon (166-180)
Chemical type: Peptide from protein
Sequence: GKTINKIDIDTEAYT
Position: 186-200
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (166-180)
Chemical type: Peptide from protein
Sequence: GKTINKIDIDTEAYT
Position: 186-200
Source molecule (GenBank): AAD24503.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AChR epsilon (166-180)
Chemical type: Peptide from protein
Sequence: GKTINKIDIDTEAYT
Position: 186-200
Source molecule (GenBank): AAD24503.1
Assay category: MhcBinding
Result: Positive-High