Reference: Dong Zhang; Feng Jiang; Rinat Zaynagetdinov; Hui Huang; Vanita D Sood; Hong Wang; Xinyan Zhao; Molly H Jenkins; Qingyong Ji; Youbin Wang; David P Nannemann; Djordje Musil; John Wesolowski; Andrea Paoletti; Tin Bartholomew; Melissa G Derner; Qi An; Christel Iffland; Joern-Peter Halle. "Identification and characterization of M6903, an antagonistic anti-TIM-3 monoclonal antibody." Oncoimmunology (2020).

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Negative

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive
Quantitative measurement: 2.3

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive
Quantitative measurement: 10.8

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive
Quantitative measurement: 180000.0

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0020

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0014

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00043

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive
Quantitative measurement: 11.8

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive
Quantitative measurement: 120000.0

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive
Quantitative measurement: 190000.0

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive
Quantitative measurement: 3.06

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive

Epitope: Epitope of M6903 Fab on TIM-3
Chemical type: Discontinuous protein residues
Discontinuous residues: P50, G56, A57, C58, P59, V60, F61, E62, C63, G64, N65, R69, E72, Q113, I114, P115, G116, I117, M118, D120, K122
Source molecule (GenBank): Q8TDQ0.3
Assay category: BCell
Result: Positive