LiteFold/IEDB huggingface dataset:
Reference: P I Karachunski; N Ostlie; M Bellone; A J Infante; B M Conti-Fine. "Mechanisms by which the I-ABM12 mutation influences susceptibility to experimental myasthenia gravis: a study in homozygous and heterozygous mice." Scandinavian journal of immunology (1995).

Epitope: Tα181-200
Chemical type: Peptide from protein
Sequence: YRGWKHWVYYTCCPDTPYLD
Position: 205-224
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: Tα181-200
Chemical type: Peptide from protein
Sequence: YRGWKHWVYYTCCPDTPYLD
Position: 205-224
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive-Low
Host:  6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: Tα181-200
Chemical type: Peptide from protein
Sequence: YRGWKHWVYYTCCPDTPYLD
Position: 205-224
Source molecule (GenBank): P02710.1
Assay category: TCell
Result: Positive
Host:  6-8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo
Reference: H Link; Z Y Xu; A Melms; H Kalbacher; J B Sun; Z Y Wang; S Fredrikson; T Olsson. "The T-cell repertoire in myasthenia gravis involves multiple cholinergic receptor epitopes." Scandinavian journal of immunology (1992).

Epitope: hAChRα207-221
Chemical type: Peptide from protein
Sequence: MQRLPLYFIVNVIIP
Position: 252-266
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  18-84 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: hAChRα207-221
Chemical type: Peptide from protein
Sequence: MQRLPLYFIVNVIIP
Position: 252-266
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive-Low
Host:  26-68 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: hAChRα235-255
Chemical type: Peptide from protein
Sequence: LPTDSGEKMTLSISVLLSLTV
Position: 280-300
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive
Host:  18-84 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: hAChRα235-255
Chemical type: Peptide from protein
Sequence: LPTDSGEKMTLSISVLLSLTV
Position: 280-300
Source molecule (GenBank): P02708.2
Assay category: TCell
Result: Positive-Low
Host:  26-68 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: S H Rhim; S E Millar; F Robey; A M Luo; Y H Lou; T Yule; P Allen; J Dean; K S Tung. "Autoimmune disease of the ovary induced by a ZP3 peptide from the mouse zona pellucida." The Journal of clinical investigation (1992).

Epitope: Mouse ZP3<sup>330-342</sup>
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): P10761.4
Assay category: TCell
Result: Positive
Host: F 6-9 weeks

Epitope: Mouse ZP3<sup>330-342</sup>
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): P10761.4
Assay category: TCell
Result: Positive
Host: F 6-9 weeks
Reference: Y H Lou; K K Park; S Agersborg; P Alard; K S Tung. "Retargeting T cell-mediated inflammation: a new perspective on autoantibody action." Journal of immunology (Baltimore, Md. : 1950) (2000).

Epitope: mZP3 (330-342)
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): P10761.4
Assay category: TCell
Result: Positive
Host: F 6-8 weeks

Epitope: mZP3 (330-342)
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): P10761.4
Assay category: TCell
Result: Positive
Host: F 6-8 weeks

Epitope: mZP3 (330-342)
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): P10761.4
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Cell Line / Clone
Reference: I N Batova; R T Richardson; E E Widgren; M G O'Rand. "Analysis of the autoimmune epitopes on human testicular NASP using recombinant and synthetic peptides." Clinical and experimental immunology (2000).

Epitope: NASP (634-642)
Chemical type: Peptide from protein
Sequence: YKKEIEELK
Position: 634-642
Source molecule (GenBank): AAA36027.1
Assay category: BCell
Result: Negative

Epitope: NASP (635-643)
Chemical type: Peptide from protein
Sequence: KKEIEELKE
Position: 635-643
Source molecule (GenBank): AAA36027.1
Assay category: BCell
Result: Negative

Epitope: NASP (636-644)
Chemical type: Peptide from protein
Sequence: KEIEELKEL
Position: 636-644
Source molecule (GenBank): AAA36027.1
Assay category: BCell
Result: Negative

Epitope: NASP (641-649)
Chemical type: Peptide from protein
Sequence: LKELLPEIR
Position: 641-649
Source molecule (GenBank): AAA36027.1
Assay category: BCell
Result: Negative

Epitope: NASP (670-678)
Chemical type: Peptide from protein
Sequence: KATLVESST
Position: 670-678
Source molecule (GenBank): AAA36027.1
Assay category: BCell
Result: Negative

Epitope: NASP (676-684)
Chemical type: Peptide from protein
Sequence: SSTSGFTPG
Position: 676-684
Source molecule (GenBank): AAA36027.1
Assay category: BCell
Result: Negative

Epitope: NASP (677-685)
Chemical type: Peptide from protein
Sequence: STSGFTPGG
Position: 677-685
Source molecule (GenBank): AAA36027.1
Assay category: BCell
Result: Negative
Reference: I A Lea; P Adoyo; M G O'Rand. "Autoimmunogenicity of the human sperm protein Sp17 in vasectomized men and identification of linear B cell epitopes." Fertility and sterility (1997).

Epitope: HSp17 (19-28)
Chemical type: Peptide from protein
Sequence: LLEGLTREIL
Position: 19-28
Source molecule (GenBank): AAH19224.1
Assay category: BCell
Result: Negative
Host: F

Epitope: HSp17 (19-28)
Chemical type: Peptide from protein
Sequence: LLEGLTREIL
Position: 19-28
Source molecule (GenBank): AAH19224.1
Assay category: BCell
Result: Negative
Host: F

Epitope: HSp17 (19-28)
Chemical type: Peptide from protein
Sequence: LLEGLTREIL
Position: 19-28
Source molecule (GenBank): AAH19224.1
Assay category: BCell
Result: Negative
Host: M

Epitope: HSp17 (55-64)
Chemical type: Peptide from protein
Sequence: FDPAEWGSKV
Position: 55-64
Source molecule (GenBank): AAH19224.1
Assay category: BCell
Result: Negative
Host: F

Epitope: HSp17 (55-64)
Chemical type: Peptide from protein
Sequence: FDPAEWGSKV
Position: 55-64
Source molecule (GenBank): AAH19224.1
Assay category: BCell
Result: Negative
Host: F

Epitope: HSp17 (55-64)
Chemical type: Peptide from protein
Sequence: FDPAEWGSKV
Position: 55-64
Source molecule (GenBank): AAH19224.1
Assay category: BCell
Result: Negative
Host: M

Epitope: HSp17 (133-142)
Chemical type: Peptide from protein
Sequence: EAKKMKTNSL
Position: 133-142
Source molecule (GenBank): NP_059121.1
Assay category: BCell
Result: Negative
Host: F

Epitope: HSp17 (133-142)
Chemical type: Peptide from protein
Sequence: EAKKMKTNSL
Position: 133-142
Source molecule (GenBank): NP_059121.1
Assay category: BCell
Result: Negative
Host: F

Epitope: HSp17 (133-142)
Chemical type: Peptide from protein
Sequence: EAKKMKTNSL
Position: 133-142
Source molecule (GenBank): NP_059121.1
Assay category: BCell
Result: Negative
Host: M
Reference: Y Lou; J Ang; H Thai; F McElveen; K S Tung. "A zona pellucida 3 peptide vaccine induces antibodies and reversible infertility without ovarian pathology." Journal of immunology (Baltimore, Md. : 1950) (1995).

Epitope: ZP3 (330-342)
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): P10761.4
Assay category: BCell
Result: Negative
Host: F 6-8 weeks

Epitope: ZP3 (330-342)
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): P10761.4
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: ZP3 (330-342)
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): P10761.4
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: ZP3 (330-342)
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): P10761.4
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: ZP3 (330-342)
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): P10761.4
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: ZP3 (330-342)
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): P10761.4
Assay category: BCell
Result: Negative
Host: F 6-8 weeks

Epitope: ZP3 (330-342)
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): P10761.4
Assay category: BCell
Result: Negative
Host: F 6-8 weeks
Reference: Y Lou; K S Tung. "T cell peptide of a self-protein elicits autoantibody to the protein antigen. Implications for specificity and pathogenetic role of antibody in autoimmunity." Journal of immunology (Baltimore, Md. : 1950) (1993).

Epitope: Mouse ZP3 330-342
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): EDL19338.1
Assay category: BCell
Result: Positive
Host: F 6-9 weeks

Epitope: Mouse ZP3 330-342
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): EDL19338.1
Assay category: BCell
Result: Positive
Host: F 6-9 weeks

Epitope: Mouse ZP3 330-342
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): EDL19338.1
Assay category: BCell
Result: Positive
Host: F 6-9 weeks

Epitope: Mouse ZP3 330-342
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): EDL19338.1
Assay category: BCell
Result: Positive
Host: F 6-9 weeks

Epitope: Mouse ZP3 330-342
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): EDL19338.1
Assay category: BCell
Result: Negative
Host: F 6-9 weeks

Epitope: Mouse ZP3 330-342
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): EDL19338.1
Assay category: TCell
Result: Positive-High
Host: F 6-9 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: Mouse ZP3 330-342
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): EDL19338.1
Assay category: TCell
Result: Positive-High
Host: F 6-9 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Mouse ZP3 330-342
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): EDL19338.1
Assay category: TCell
Result: Positive
Host: F 6-9 weeks
Reference: H Bagavant; S Adams; P Terranova; A Chang; F W Kraemer; Y Lou; K Kasai; A M Luo; K S Tung. "Autoimmune ovarian inflammation triggered by proinflammatory (Th1) T cells is compatible with normal ovarian function in mice." Biology of reproduction (1999).

Epitope: ZP3 (330-342)
Chemical type: Peptide from protein
Sequence: NSSSSQFQIHGPR
Position: 330-342
Source molecule (GenBank): P10761.4
Assay category: TCell
Result: Positive
Host: F
Reference: S K Gupta; E C Yurewicz; A Afzalpurkar; K V Rao; D A Gage; H Wu; A G Sacco. "Localization of epitopes for monoclonal antibodies at the N-terminus of the porcine zona pellucida glycoprotein pZPC." Molecular reproduction and development (1995).

Epitope: pZP3 (25-29)
Chemical type: Peptide from protein
Sequence: VWQDE
Position: 25-29
Source molecule (GenBank): NP_999058.1
Assay category: BCell
Result: Positive

Epitope: pZP3 (25-29)
Chemical type: Peptide from protein
Sequence: VWQDE
Position: 25-29
Source molecule (GenBank): NP_999058.1
Assay category: BCell
Result: Positive

Epitope: pZP3 (25-29)
Chemical type: Peptide from protein
Sequence: VWQDE
Position: 25-29
Source molecule (GenBank): NP_999058.1
Assay category: BCell
Result: Positive

Epitope: pZP3 (25-29)
Chemical type: Peptide from protein
Sequence: VWQDE
Position: 25-29
Source molecule (GenBank): NP_999058.1
Assay category: BCell
Result: Positive
Reference: John Walker; Souravi Ghosh; Joanne Pagnon; Caterina Colantoni; Andrea Newbold; Weiguang Zeng; David C Jackson. "Totally synthetic peptide-based immunocontraceptive vaccines show activity in dogs of different breeds." Vaccine (2007).

Epitope: P2
Chemical type: Peptide from protein
Sequence: SSKTQTHTQQDRPPQPS
Position: 8-24
Source molecule (GenBank): AAA42878.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: H Hanawa; T Inomata; Y Okura; S Hirono; Y Ogawa; T Izumi; M Kodama; Y Aizawa. "T cells with similar T-cell receptor beta-chain complementarity-determining region 3 motifs infiltrate inflammatory lesions of synthetic peptides inducing rat autoimmune myocarditis." Circulation research (1998).

Epitope: CM2
Chemical type: Peptide from protein
Sequence: KLELQSALEEAEASLEH
Position: 1539-1555
Source molecule (GenBank): NP_058935.2
Assay category: TCell
Result: Positive
Host:  6 weeks
Reference: H F Becker; Y Corda; M B Mathews; J L Fourrey; H Grosjean. "Inosine and N1-methylinosine within a synthetic oligomer mimicking the anticodon loop of human tRNA(Ala) are major epitopes for anti-PL-12 myositis autoantibodies." RNA (New York, N.Y.) (1999).

Epitope: structure 8
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Negative
Reference: E V Fedoseyeva; F Zhang; P L Orr; D Levin; H J Buncke; G Benichou. "De novo autoimmunity to cardiac myosin after heart transplantation and its contribution to the rejection process." Journal of immunology (Baltimore, Md. : 1950) (1999).

Epitope: myhc alpha 334-352
Chemical type: Peptide from protein
Sequence: DSAFDVLSFTAEEKAGVYK
Position: 334-352
Source molecule (GenBank): AAA37161.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: myhc alpha 334-352
Chemical type: Peptide from protein
Sequence: DSAFDVLSFTAEEKAGVYK
Position: 334-352
Source molecule (GenBank): AAA37161.1
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo
Reference: C L Pummerer; K Luze; G Grässl; K Bachmaier; F Offner; S K Burrell; D M Lenz; T J Zamborelli; J M Penninger; N Neu. "Identification of cardiac myosin peptides capable of inducing autoimmune myocarditis in BALB/c mice." The Journal of clinical investigation (1996).

Epitope: α-Myosin 735-747
Chemical type: Peptide from protein
Sequence: GQFIDSGKAGAEKL
Assay category: TCell
Result: Positive
Host:  6-8 weeks

Epitope: α-Myosin 986-998
Chemical type: Peptide from protein
Sequence: GLDEIIAKLTKEK
Position: 986-998
Source molecule (GenBank): NP_058935.2
Assay category: TCell
Result: Negative
Host:  6-8 weeks

Epitope: α-Myosin 947-960
Chemical type: Peptide from protein
Sequence: DECSELKKDIDDLE
Position: 947-960
Source molecule (GenBank): NP_058935.2
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Reference: D L Donermeyer; K W Beisel; P M Allen; S C Smith. "Myocarditis-inducing epitope of myosin binds constitutively and stably to I-Ak on antigen-presenting cells in the heart." The Journal of experimental medicine (1995).

Epitope: myhcα 334-352
Chemical type: Peptide from protein
Sequence: DSAFDVLSFTAEEKAGVYK
Position: 334-352
Source molecule (GenBank): AAA37161.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: myhcα 334-352
Chemical type: Peptide from protein
Sequence: DSAFDVLSFTAEEKAGVYK
Position: 334-352
Source molecule (GenBank): AAA37161.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: myhcα 334-352
Chemical type: Peptide from protein
Sequence: DSAFDVLSFTAEEKAGVYK
Position: 334-352
Source molecule (GenBank): AAA37161.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: myhcα 334-352
Chemical type: Peptide from protein
Sequence: DSAFDVLSFTAEEKAGVYK
Position: 334-352
Source molecule (GenBank): AAA37161.1
Assay category: TCell
Result: Positive
Cell type: T cell hybridoma
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: myhcα 334-352
Chemical type: Peptide from protein
Sequence: DSAFDVLSFTAEEKAGVYK
Position: 334-352
Source molecule (GenBank): AAA37161.1
Assay category: TCell
Result: Positive
Host: M

Epitope: myhcα 334-352
Chemical type: Peptide from protein
Sequence: DSAFDVLSFTAEEKAGVYK
Position: 334-352
Source molecule (GenBank): AAA37161.1
Assay category: MhcBinding
Result: Positive

Epitope: RNase(43-56)
Chemical type: Peptide from protein
Sequence: VNTFVHESLADVQA
Position: 69-82
Source molecule (GenBank): P61823.1
Assay category: MhcBinding
Result: Positive
Reference: Kathleen P Pratt; Jiahua Qian; Ekram Ellaban; David K Okita; Brenda M Diethelm-Okita; Bianca Conti-Fine; David W Scott. "Immunodominant T-cell epitopes in the factor VIII C2 domain are located within an inhibitory antibody binding site." Thrombosis and haemostasis (2004).

Epitope: C2-1
Chemical type: Peptide from protein
Sequence: LNSCSMPLGMESKAISDAQI
Position: 2190-2209
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: C2-1
Chemical type: Peptide from protein
Sequence: LNSCSMPLGMESKAISDAQI
Position: 2190-2209
Source molecule (GenBank): AAA52420.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo
Reference: Sylvie Villard; Dominique Piquer; Sanjee Raut; Jean-Paul Léonetti; Jean-Marie Saint-Remy; Claude Granier. "Low molecular weight peptides restore the procoagulant activity of factor VIII in the presence of the potent inhibitor antibody ESH8." The Journal of biological chemistry (2002).

Epitope: Peptide 46
Chemical type: Peptide, no natural source
Sequence: ECIVYGKTALCT
Assay category: BCell
Result: Positive
Host: F 12 weeks

Epitope: Peptide 46
Chemical type: Peptide, no natural source
Sequence: ECIVYGKTALCT
Assay category: BCell
Result: Positive
Host: F 12 weeks

Epitope: Peptide 46
Chemical type: Peptide, no natural source
Sequence: ECIVYGKTALCT
Assay category: BCell
Result: Positive
Host: F 12 weeks

Epitope: Peptide 73
Chemical type: Peptide, no natural source
Sequence: YCNPSIGDKNCR
Assay category: BCell
Result: Positive
Host: F 12 weeks

Epitope: Peptide 73
Chemical type: Peptide, no natural source
Sequence: YCNPSIGDKNCR
Assay category: BCell
Result: Positive
Host: F 12 weeks

Epitope: Peptide 73
Chemical type: Peptide, no natural source
Sequence: YCNPSIGDKNCR
Assay category: BCell
Result: Positive
Host: F 12 weeks
Reference: Christa Mersich; Werner Billes; Ingrid Pabinger; Alois Jungbauer. "Peptides derived from a secretory yeast library restore factor VIII activity in the presence of an inhibitory antibody." Biotechnology and bioengineering (2007).

Epitope: 009D3
Chemical type: Peptide, no natural source
Sequence: PAFSCWKWVTVLVICPTRFARPNNAFLYDA
Assay category: BCell
Result: Positive

Epitope: 033A7
Chemical type: Peptide, no natural source
Sequence: TRKPSWPSLHQG
Assay category: BCell
Result: Positive
Reference: Mario Di Giambattista; Theo Branckaert; Vincent Hougardy; Geoffrey Kemball-Cook; Ruth Laub. "In silico prediction of FVIII epitopes recognised by natural autoantibodies in polyvalent immunoglobulin concentrates." Molecular immunology (2007).

Epitope: P9
Chemical type: Peptide from protein
Sequence: RTTLQSDQEEIDY
Position: 1671-1683
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive
Host: F

Epitope: P9
Chemical type: Peptide from protein
Sequence: RTTLQSDQEEIDY
Position: 1671-1683
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive
Host: F

Epitope: P9
Chemical type: Peptide from protein
Sequence: RTTLQSDQEEIDY
Position: 1671-1683
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive

Epitope: P9
Chemical type: Peptide from protein
Sequence: RTTLQSDQEEIDY
Position: 1671-1683
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Negative

Epitope: P6
Chemical type: Peptide from protein
Sequence: LSKNNAIEPRSFSQNSRHPS
Position: 750-769
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive-Intermediate
Reference: I M Lubin; J F Healey; R T Barrow; D Scandella; P Lollar. "Analysis of the human factor VIII A2 inhibitor epitope by alanine scanning mutagenesis." The Journal of biological chemistry (1997).

Epitope: fVIII mutants
Chemical type: Discontinuous protein residues
Discontinuous residues: Y506, S507, R508, P511, V514, F520, I527
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive
Reference: T D Jones; W J Phillips; B J Smith; C A Bamford; P D Nayee; T P Baglin; J S H Gaston; M P Baker. "Identification and removal of a promiscuous CD4+ T cell epitope from the C1 domain of factor VIII." Journal of thrombosis and haemostasis : JTH (2005).

Epitope: Human FVIII peptide 333
Chemical type: Peptide from protein
Sequence: FTENMERNCRAPCNI
Position: 1910-1924
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: Human FVIII peptide 450
Chemical type: Peptide from protein
Sequence: GVTTQGVKSLLTSMY
Position: 2261-2275
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HLA-DQB1*0603 21–36
Chemical type: Peptide from protein
Sequence: TERVRLVTRHIYNREE
Position: 13-28
Source molecule (GenBank): O78046
Assay category: MhcBinding
Result: Positive-High
Reference: Marc Jacquemin; Valérie Vantomme; Cécile Buhot; Renaud Lavend'homme; Wivine Burny; Nathalie Demotte; Pascal Chaux; Kathelijne Peerlinck; Jos Vermylen; Bernard Maillere; Pierre van der Bruggen; Jean-Marie Saint-Remy. "CD4+ T-cell clones specific for wild-type factor VIII: a molecular mechanism responsible for a higher incidence of inhibitor formation in mild/moderate hemophilia A." Blood (2003).

Epitope: B1 21-36
Chemical type: Peptide from protein
Sequence: TERVRLVTRHIYNREE
Position: 13-28
Source molecule (GenBank): ACZ73275.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 450.0
Reference: P A Foster; C A Fulcher; R A Houghten; T S Zimmerman. "An immunogenic region within residues Val1670-Glu1684 of the factor VIII light chain induces antibodies which inhibit binding of factor VIII to von Willebrand factor." The Journal of biological chemistry (1988).

Epitope: FVIII (1655-1669)
Chemical type: Peptide from protein
Sequence: LQSDQEEIDYDDTIS
Position: 1674-1688
Source molecule (GenBank): AAA52420.1
Assay category: BCell
Result: Negative
Reference: M R Stanford; E Kasp; R Whiston; A Hasan; S Todryk; T Shinnick; Y Mizushima; D C Dumonde; R van der Zee; T Lehner. "Heat shock protein peptides reactive in patients with Behçet's disease are uveitogenic in Lewis rats." Clinical and experimental immunology (1994).

Epitope: M bovis hsp 154-172
Chemical type: Peptide from protein
Sequence: QSIGDLIAEAMDKVGNEGV
Position: 93-111
Source molecule (GenBank): AAQ64500.1
Assay category: TCell
Result: Negative
Host: M
Reference: L A Donoso; C F Merryman; T W Sery; T Shinohara; B Dietzschold; A Smith; C M Kalsow. "S-antigen: characterization of a pathogenic epitope which mediates experimental autoimmune uveitis and pinealitis in Lewis rats." Current eye research (1987).

Epitope: Peptide 3
Chemical type: Peptide from protein
Sequence: PVTVAVTNSTEKTVKKIKVL
Position: 221-240
Source molecule (GenBank): P08168.1
Assay category: TCell
Result: Negative
Host: F

Epitope: Peptide K
Chemical type: Peptide from protein
Sequence: VEQVTNVGLYSSDYYIKTVA
Assay category: TCell
Result: Negative
Host: F