Reference: Marie Eliane Azoury; Mahmoud Tarayrah; Georgia Afonso; Aurore Pais; Maikel L Colli; Claire Maillard; Cassandra Lavaud; Laure Alexandre-Heymann; Sergio Gonzalez-Duque; Yann Verdier; Joelle Vinh; Sheena Pinto; Soren Buus; Danièle Dubois-Laforgue; Etienne Larger; Jean-Paul Beressi; Graziella Bruno; Decio L Eizirik; Sylvaine You; Roberto Mallone. "Peptides Derived From Insulin Granule Proteins Are Targeted by CD8<sup>+</sup> T Cells Across MHC Class I Restrictions in Humans and NOD Mice." Diabetes (2020).

Epitope: CADPS1/2 780-788
Chemical type: Peptide from protein
Sequence: SLLERVLMK
Position: 780-788
Source molecule (GenBank): Q86UW7.2
Assay category: TCell
Result: Positive
Host:  24-47 years
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: CADPS1/2 780-788
Chemical type: Peptide from protein
Sequence: SLLERVLMK
Position: 780-788
Source molecule (GenBank): Q86UW7.2
Assay category: MhcLigandElution
Result: Positive

Epitope: CADPS1/2 780-788
Chemical type: Peptide from protein
Sequence: SLLERVLMK
Position: 780-788
Source molecule (GenBank): Q86UW7.2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 247.6

Epitope: CHGB 603-613
Chemical type: Peptide from protein
Sequence: RVAQLDQLLHY
Position: 603-613
Source molecule (GenBank): P05060.2
Assay category: TCell
Result: Positive
Host:  24-47 years
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: CHGB 603-613
Chemical type: Peptide from protein
Sequence: RVAQLDQLLHY
Position: 603-613
Source molecule (GenBank): P05060.2
Assay category: MhcLigandElution
Result: Positive

Epitope: CHGB 603-613
Chemical type: Peptide from protein
Sequence: RVAQLDQLLHY
Position: 603-613
Source molecule (GenBank): P05060.2
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 72.7

Epitope: PTPRN 156-164
Chemical type: Peptide from protein
Sequence: RLPQPPVGK
Position: 156-164
Source molecule (GenBank): Q16849.1
Assay category: TCell
Result: Positive
Host:  24-47 years
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: PTPRN 156-164
Chemical type: Peptide from protein
Sequence: RLPQPPVGK
Position: 156-164
Source molecule (GenBank): Q16849.1
Assay category: MhcLigandElution
Result: Positive

Epitope: PTPRN 156-164
Chemical type: Peptide from protein
Sequence: RLPQPPVGK
Position: 156-164
Source molecule (GenBank): Q16849.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 151.9

Epitope: PTPRN/PTPRN 576-580/708-711
Chemical type: Peptide from protein
Sequence: SVLLTRLAK
Assay category: TCell
Result: Positive
Host:  22-40 years
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: PTPRN/PTPRN 576-580/708-711
Chemical type: Peptide from protein
Sequence: SVLLTRLAK
Assay category: TCell
Result: Positive
Host:  24-47 years
Cell type: T cell CD8+
Tissue: pancreas
Culture conditions: Direct Ex Vivo

Epitope: PTPRN/PTPRN 576-580/708-711
Chemical type: Peptide from protein
Sequence: SVLLTRLAK
Assay category: MhcLigandElution
Result: Positive

Epitope: PTPRN/PTPRN 576-580/708-711
Chemical type: Peptide from protein
Sequence: SVLLTRLAK
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 54.3