Reference: Miaojuan Huang; Rong Xu; Cristina Triffon; Nicole Mifsud; Weisan Chen. "Broad-Based Influenza-Specific CD8<sup>+</sup> T Cell Response without the Typical Immunodominance Hierarchy and Its Potential Implication." Viruses (2021).

Epitope: NS1 127-144
Chemical type: Peptide from protein
Sequence: NIILKANFSVIFDRLETL
Position: 127-144
Source molecule (GenBank): P03496.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NS1 145-162
Chemical type: Peptide from protein
Sequence: ILLRAFTEEGAIVGEISP
Position: 145-162
Source molecule (GenBank): P03496.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 61-78
Chemical type: Peptide from protein
Sequence: GFVFTLTVPSERGLQRRR
Position: 61-78
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 67-84
Chemical type: Peptide from protein
Sequence: TVPSERGLQRRRFVQNAL
Position: 67-84
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 109-126
Chemical type: Peptide from protein
Sequence: FHGAKEISLSYSAGALAS
Position: 109-126
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 133-150
Chemical type: Peptide from protein
Sequence: NRMGAVTTEVAFGLVCAT
Position: 133-150
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 157-174
Chemical type: Peptide from protein
Sequence: SQHRSHRQMVTTTNPLIR
Position: 157-174
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 169-186
Chemical type: Peptide from protein
Sequence: TNPLIRHENRMVLASTTA
Position: 169-186
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M2 37-54
Chemical type: Peptide from protein
Sequence: HLTLWILDRLFFKCIYRR
Position: 37-54
Source molecule (GenBank): ADE29099.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M2 67-84
Chemical type: Peptide from protein
Sequence: GVPKSMREEYRKEQQSAV
Position: 67-84
Source molecule (GenBank): P06821.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NA 7-24
Chemical type: Peptide from protein
Sequence: ITTIGSICLVVGLISLIL
Position: 7-24
Source molecule (GenBank): AAM75160.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NA 13-24
Chemical type: Peptide from protein
Sequence: ICLVVGLISLILQIGNII
Position: 13-30
Source molecule (GenBank): P03468.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NA 37-54
Chemical type: Peptide from protein
Sequence: SIQTGSQNHTGICNQNII
Position: 37-54
Source molecule (GenBank): P03468.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NA 43-60
Chemical type: Peptide from protein
Sequence: QNHTGICNQNIITYKNST
Position: 43-60
Source molecule (GenBank): P03468.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NA 97-114
Chemical type: Peptide from protein
Sequence: GDVFVIREPFISCSHLEC
Position: 97-114
Source molecule (GenBank): P03468.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NA 115-132
Chemical type: Peptide from protein
Sequence: RTFFLTQGALLNDKHSNG
Position: 115-132
Source molecule (GenBank): P03468.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NA 205-222
Chemical type: Peptide from protein
Sequence: RKKILRTQESECACVNGS
Position: 205-222
Source molecule (GenBank): P03468.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NA 247-264
Chemical type: Peptide from protein
Sequence: KVTKSIELNAPNSHYEEC
Position: 247-264
Source molecule (GenBank): P03468.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NA 271-288
Chemical type: Peptide from protein
Sequence: GKVMCVCRDNWHGSNRPW
Position: 271-288
Source molecule (GenBank): P03468.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NA 289-306
Chemical type: Peptide from protein
Sequence: VSFDQNLDYQIGYICSGV
Position: 289-306
Source molecule (GenBank): P03468.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NA 337-354
Chemical type: Peptide from protein
Sequence: RYGNGVWIGRTKSHSSRH
Position: 337-354
Source molecule (GenBank): P03468.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NA 343-360
Chemical type: Peptide from protein
Sequence: WIGRTKSHSSRHGFEMIW
Position: 343-360
Source molecule (GenBank): P03468.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NP 67-84
Chemical type: Peptide from protein
Sequence: VLSAFDERRNKYLEEHPS
Position: 67-84
Source molecule (GenBank): P03466.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NP 73-90
Chemical type: Peptide from protein
Sequence: ERRNKYLEEHPSAGKDPK
Position: 73-90
Source molecule (GenBank): P03466.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NP 127-144
Chemical type: Peptide from protein
Sequence: DDATAGLTHMMIWHSNLN
Position: 127-144
Source molecule (GenBank): P03466.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NP 181-198
Chemical type: Peptide from protein
Sequence: AAVKGVGTMVMELVRMIK
Position: 181-198
Source molecule (GenBank): P03466.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NP 289-306
Chemical type: Peptide from protein
Sequence: YDFEREGYSLVGIDPFRL
Position: 289-306
Source molecule (GenBank): P03466.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NP 319-336
Chemical type: Peptide from protein
Sequence: NENPAHKSQLVWMACHSA
Position: 319-336
Source molecule (GenBank): P03466.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HA 31-48
Chemical type: Peptide from protein
Sequence: DTVDTVLEKNVTVTHSVN
Position: 31-48
Source molecule (GenBank): P03452.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HA 49-66
Chemical type: Peptide from protein
Sequence: LLEDSHNGKLCRLKGIAP
Position: 49-66
Source molecule (GenBank): P03452.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HA 139-156
Chemical type: Peptide from protein
Sequence: SWPNHNTNGVTAACSHEG
Position: 139-156
Source molecule (GenBank): P03452.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HA 193-210
Chemical type: Peptide from protein
Sequence: WGIHHPPNSKEQQNIYQN
Position: 193-210
Source molecule (GenBank): AAM75158.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HA 265-282
Chemical type: Peptide from protein
Sequence: IAPMYAFALSRGFGSGII
Position: 265-282
Source molecule (GenBank): P03452.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HA 283-300
Chemical type: Peptide from protein
Sequence: TSNASMHECNTKCQTPLG
Position: 283-300
Source molecule (GenBank): P03452.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HA 307-324
Chemical type: Peptide from protein
Sequence: PYQNIHPVTIGECPKYVR
Position: 307-324
Source molecule (GenBank): P03452.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HA 391-408
Chemical type: Peptide from protein
Sequence: ITNKVNTVIEKMNIQFTA
Position: 391-408
Source molecule (GenBank): P03452.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HA 409-426
Chemical type: Peptide from protein
Sequence: VGKEFNKLEKRMENLNKK
Position: 409-426
Source molecule (GenBank): P03452.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HA 493-510
Chemical type: Peptide from protein
Sequence: ESVRNGTYDYPKYSEESK
Position: 493-510
Source molecule (GenBank): P03452.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HA 499-516
Chemical type: Peptide from protein
Sequence: TYDYPKYSEESKLNREKV
Position: 499-516
Source molecule (GenBank): P03452.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: HA 547-564
Chemical type: Peptide from protein
Sequence: GAISFWMCSNGSLQCRIC
Position: 547-564
Source molecule (GenBank): P03452.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PB2 25-42
Chemical type: Peptide from protein
Sequence: VDHMAIIKKYTSGRQEKN
Position: 25-42
Source molecule (GenBank): P03428.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PB2 205-222
Chemical type: Peptide from protein
Sequence: YMLERELVRKTRFLPVAG
Position: 205-222
Source molecule (GenBank): P03428.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PB2 265-282
Chemical type: Peptide from protein
Sequence: NIVRRAAVSADPLASLLE
Position: 265-282
Source molecule (GenBank): P03428.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PB2 324-342
Chemical type: Peptide from protein
Sequence: FGGFTFKRTSGSSVKREE
Position: 325-342
Source molecule (GenBank): P03428.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PB2 367-384
Chemical type: Peptide from protein
Sequence: GRRATAILRKATRRLIQL
Position: 367-384
Source molecule (GenBank): P03428.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PB2 457-474
Chemical type: Peptide from protein
Sequence: VMGMIGILPDMTPSIEMS
Position: 457-474
Source molecule (GenBank): P03428.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PB2 565-582
Chemical type: Peptide from protein
Sequence: SQNPTMLYNKMEFEPFQS
Position: 565-582
Source molecule (GenBank): P03428.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PB2 667-684
Chemical type: Peptide from protein
Sequence: VLGKDAGTLTEDPDEGTA
Position: 667-684
Source molecule (GenBank): P03428.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PB2 721-738
Chemical type: Peptide from protein
Sequence: KANVLIGQGDVVLVMKRK
Position: 721-738
Source molecule (GenBank): P03428.2
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M1 124-134
Chemical type: Peptide from protein
Sequence: LASCMGLIYN
Position: 124-133
Source molecule (GenBank): P03485.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PB2 39-49
Chemical type: Peptide from protein
Sequence: QEKNPALRMKW
Position: 39-49
Source molecule (GenBank): P03428.2
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone