Reference: Sofie Kirial Mørk; Signe Koggersbøl Skadborg; Benedetta Albieri; Arianna Draghi; Kalijn Bol; Mohammad Kadivar; Marie Christine Wulff Westergaard; Joachim Stoltenborg Granhøj; Annie Borch; Nadia Viborg Petersen; Nikolas Thuesen; Ida Svahn Rasmussen; Lars Vibe Andreasen; Rebecca Bach Dohn; Christina Westmose Yde; Nis Noergaard; Torben Lorentzen; Anders Bundgaard Soerensen; Daniela Kleine-Kohlbrecher; Anders Jespersen; Dennis Christensen; Jens Kringelum; Marco Donia; Sine Reker Hadrup; Inge Marie Svane. "Dose escalation study of a personalized peptide-based neoantigen vaccine (EVX-01) in patients with metastatic melanoma." Journal for immunotherapy of cancer (2024).

Epitope: PT01 Neo ISNAMSAAY
Chemical type: Peptide, no natural source
Sequence: ISNAMSAAY
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PT01 Vaccpep5 IYNNVLQLIKV
Chemical type: Peptide, no natural source
Sequence: IYNNVLQLIKV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PT01 Vaccpep5 IYNNVLQLIKV
Chemical type: Peptide, no natural source
Sequence: IYNNVLQLIKV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PT01 Vaccpep5 IYNNVLQLIKV
Chemical type: Peptide, no natural source
Sequence: IYNNVLQLIKV
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Short Term Restimulated

Epitope: PT01 Vaccpep5 SIYNNVLQLI
Chemical type: Peptide, no natural source
Sequence: SIYNNVLQLI
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PT01 Vaccpep5 SIYNNVLQLI
Chemical type: Peptide, no natural source
Sequence: SIYNNVLQLI
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PT01 Vaccpep5 SIYNNVLQLI
Chemical type: Peptide, no natural source
Sequence: SIYNNVLQLI
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Short Term Restimulated

Epitope: PT02 Neo FLYAYLDILL
Chemical type: Peptide, no natural source
Sequence: FLYAYLDILL
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PT03 Neo EFDDGAEEI
Chemical type: Peptide, no natural source
Sequence: EFDDGAEEI
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PT03 Neo SSLRNIWKK
Chemical type: Peptide, no natural source
Sequence: SSLRNIWKK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PT03 Vaccpep7 RSLKPVLSHK
Chemical type: Peptide, no natural source
Sequence: RSLKPVLSHK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PT08 Neo HMKYFRGMEK
Chemical type: Peptide, no natural source
Sequence: HMKYFRGMEK
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PT06 Peptide 2
Chemical type: Peptide, no natural source
Sequence: ETLEAMQRESRRLLPIQKPKLLRPRLL
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT06 Peptide 2
Chemical type: Peptide, no natural source
Sequence: ETLEAMQRESRRLLPIQKPKLLRPRLL
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT06 Peptide 2
Chemical type: Peptide, no natural source
Sequence: ETLEAMQRESRRLLPIQKPKLLRPRLL
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT06 Peptide 2
Chemical type: Peptide, no natural source
Sequence: ETLEAMQRESRRLLPIQKPKLLRPRLL
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT09 Peptide 4
Chemical type: Peptide, no natural source
Sequence: SSQSSQGAQSLTFFKFEEKKTNEKTRK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT09 Peptide 4
Chemical type: Peptide, no natural source
Sequence: SSQSSQGAQSLTFFKFEEKKTNEKTRK
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT09 Peptide 4
Chemical type: Peptide, no natural source
Sequence: SSQSSQGAQSLTFFKFEEKKTNEKTRK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT09 Peptide 4
Chemical type: Peptide, no natural source
Sequence: SSQSSQGAQSLTFFKFEEKKTNEKTRK
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT09 Peptide 4
Chemical type: Peptide, no natural source
Sequence: SSQSSQGAQSLTFFKFEEKKTNEKTRK
Assay category: TCell
Result: Negative
Cell type: lymphocyte
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT09 Peptide 4
Chemical type: Peptide, no natural source
Sequence: SSQSSQGAQSLTFFKFEEKKTNEKTRK
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT09 Peptide 4
Chemical type: Peptide, no natural source
Sequence: SSQSSQGAQSLTFFKFEEKKTNEKTRK
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT09 Peptide 6
Chemical type: Peptide, no natural source
Sequence: KTIEDVREFLGRHFERFDRNIASFHRT
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT09 Peptide 6
Chemical type: Peptide, no natural source
Sequence: KTIEDVREFLGRHFERFDRNIASFHRT
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT09 Peptide 6
Chemical type: Peptide, no natural source
Sequence: KTIEDVREFLGRHFERFDRNIASFHRT
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT09 Peptide 6
Chemical type: Peptide, no natural source
Sequence: KTIEDVREFLGRHFERFDRNIASFHRT
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT09 Peptide 6
Chemical type: Peptide, no natural source
Sequence: KTIEDVREFLGRHFERFDRNIASFHRT
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT09 Peptide 6
Chemical type: Peptide, no natural source
Sequence: KTIEDVREFLGRHFERFDRNIASFHRT
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT09 Peptide 6
Chemical type: Peptide, no natural source
Sequence: KTIEDVREFLGRHFERFDRNIASFHRT
Assay category: TCell
Result: Negative
Cell type: lymphocyte
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: PT12 Peptide 2
Chemical type: Peptide, no natural source
Sequence: DLPAAGGPPSGAMLFYNPAQLAQA
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo