Reference: Chanchan Xiao; Jian Xiang; Haoyun Wang; Wen Gao; Tianchan Peng; Shumin Li; Jun Su; Xi Chen; Lijuan Gao; Ruohu Shi; Xinyi Mou; Jun Yuan; Guobing Chen. "Characterizing HLA-A2-restricted CD8<sup>+</sup> T-cell epitopes and immune responses to Omicron variants in SARS-CoV-2-inactivated vaccine recipients." Frontiers in immunology (2025).

Epitope: ORF1a 2083-2090 S2083I
Chemical type: Peptide from protein
Sequence: ILKITEEV
Position: 2083-2090
Source molecule (GenBank): UFL70378.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ORF1a 2083-2090 S2083I
Chemical type: Peptide from protein
Sequence: ILKITEEV
Position: 2083-2090
Source molecule (GenBank): UFL70378.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: ORF1a 2076-2086 Δ2084
Chemical type: Peptide from protein
Sequence: ILKPANNSKI
Position: 2076-2085
Source molecule (GenBank): WKP64534.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ORF1a 2076-2086 Δ2084
Chemical type: Peptide from protein
Sequence: ILKPANNSKI
Position: 2076-2085
Source molecule (GenBank): WKP64534.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: ORF1a 3250-3261 T3255I
Chemical type: Peptide from protein
Sequence: YQPPQISITSAV
Position: 3250-3261
Source molecule (GenBank): UFL70378.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ORF1a 3250-3261 T3255I
Chemical type: Peptide from protein
Sequence: YQPPQISITSAV
Position: 3250-3261
Source molecule (GenBank): UFL70378.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: ORF1b 1561-1569 Ancestral
Chemical type: Peptide from protein
Sequence: GLCVDIPGI
Position: 5962-5970
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ORF1b 1561-1569 Ancestral
Chemical type: Peptide from protein
Sequence: GLCVDIPGI
Position: 5962-5970
Source molecule (GenBank): P0DTD1.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: S 204-213 Δ212
Chemical type: Peptide from protein
Sequence: YSKHTPINV
Position: 204-212
Source molecule (GenBank): QTM40532.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: S 204-213 Δ212
Chemical type: Peptide from protein
Sequence: YSKHTPINV
Position: 204-212
Source molecule (GenBank): QTM40532.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: S 332-341 G339D
Chemical type: Peptide from protein
Sequence: ITNLCPFDEV
Position: 329-338
Source molecule (GenBank): BFN72741.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: S 332-341 G339D
Chemical type: Peptide from protein
Sequence: ITNLCPFDEV
Position: 329-338
Source molecule (GenBank): BFN72741.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: S 761-770 Ancestral
Chemical type: Peptide from protein
Sequence: TQLNRALTGI
Position: 761-770
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: S 761-770 Ancestral
Chemical type: Peptide from protein
Sequence: TQLNRALTGI
Position: 761-770
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: S 964-972 N969K
Chemical type: Peptide from protein
Sequence: KQLSSKFGA
Position: 977-985
Source molecule (GenBank): BFJ14421.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: S 964-972 N969K
Chemical type: Peptide from protein
Sequence: KQLSSKFGA
Position: 977-985
Source molecule (GenBank): BFJ14421.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: M 61-70 Ancestral
Chemical type: Peptide from protein
Sequence: TLACFVLAAV
Position: 61-70
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: M 61-70 Ancestral
Chemical type: Peptide from protein
Sequence: TLACFVLAAV
Position: 61-70
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Positive-Low