Reference: Aisha M Mergaert; Zihao Zheng; Michael F Denny; Maya F Amjadi; S Janna Bashar; Michael A Newton; Vivianne Malmström; Caroline Grönwall; Sara S McCoy; Miriam A Shelef. "Rheumatoid Factor and Anti-Modified Protein Antibody Reactivities Converge on IgG Epitopes." Arthritis & rheumatology (Hoboken, N.J.) (2022).

Epitope: IgG1 14-26 modified
Chemical type: Peptide from protein
Sequence: SSKSTSGGTAAL
Position: 14-25
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1 14-26 modified
Chemical type: Peptide from protein
Sequence: SSKSTSGGTAAL
Position: 14-25
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Positive
Host:  median: 54 years

Epitope: IgG1 89-101
Chemical type: Peptide from protein
Sequence: PSNTKVDKKVEP
Position: 89-100
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Negative
Host:  median: 54 years

Epitope: IgG1 89-101
Chemical type: Peptide from protein
Sequence: PSNTKVDKKVEP
Position: 89-100
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1 112-124
Chemical type: Peptide from protein
Sequence: CPAPELLGGPSV
Position: 159-170
Source molecule (GenBank): P01860.2
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1 112-124
Chemical type: Peptide from protein
Sequence: CPAPELLGGPSV
Position: 159-170
Source molecule (GenBank): P01860.2
Assay category: BCell
Result: Positive
Host:  median: 54 years

Epitope: IgG1 168-180 citrullination
Chemical type: Peptide from protein
Sequence: HNAKTKPREEQY
Position: 215-226
Source molecule (GenBank): P01860.2
Assay category: BCell
Result: Positive
Host:  median: 54 years

Epitope: IgG1 168-180 citrullination
Chemical type: Peptide from protein
Sequence: HNAKTKPREEQY
Position: 215-226
Source molecule (GenBank): P01860.2
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1 172-184 modified
Chemical type: Peptide from protein
Sequence: TKPREEQYNSTY
Position: 172-183
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1 172-184 modified
Chemical type: Peptide from protein
Sequence: TKPREEQYNSTY
Position: 172-183
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Positive
Host:  median: 54 years

Epitope: IgG1 176-188
Chemical type: Peptide from protein
Sequence: EEQYNSTYRVVS
Position: 176-187
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Negative
Host:  median: 54 years

Epitope: IgG1 176-188
Chemical type: Peptide from protein
Sequence: EEQYNSTYRVVS
Position: 176-187
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1-219
Chemical type: Peptide from protein
Sequence: ISKAKGQPREPQVYTLPPSRDEL
Position: 219-241
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Positive
Host:  median: 54 years

Epitope: IgG1-219
Chemical type: Peptide from protein
Sequence: ISKAKGQPREPQVYTLPPSRDEL
Position: 219-241
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1-219JB
Chemical type: Peptide from protein
Sequence: ISKAKGQPREPQVYTLPPSRDEL
Position: 219-241
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1-219JB
Chemical type: Peptide from protein
Sequence: ISKAKGQPREPQVYTLPPSRDEL
Position: 219-241
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Positive
Host:  median: 54 years

Epitope: IgG1-219JB
Chemical type: Peptide from protein
Sequence: ISKAKGQPREPQVYTLPPSRDEL
Position: 219-241
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Positive

Epitope: IgG1 226-238
Chemical type: Peptide from protein
Sequence: PREPQVYTLPPS
Position: 222-233
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1 226-238
Chemical type: Peptide from protein
Sequence: PREPQVYTLPPS
Position: 222-233
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Negative
Host:  median: 54 years

Epitope: IgG1 229-241
Chemical type: Peptide from protein
Sequence: PQVYTLPPSRDE
Position: 229-240
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1 229-241
Chemical type: Peptide from protein
Sequence: PQVYTLPPSRDE
Position: 229-240
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Positive
Host:  median: 54 years

Epitope: IgG1 230-242
Chemical type: Peptide from protein
Sequence: QVYTLPPSRDEL
Position: 230-241
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1 230-242
Chemical type: Peptide from protein
Sequence: QVYTLPPSRDEL
Position: 230-241
Source molecule (GenBank): P01857.1
Assay category: BCell
Result: Positive
Host:  median: 54 years

Epitope: IgG1 264-276 modified
Chemical type: Peptide from protein
Sequence: WESNGQPENNYK
Position: 260-271
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1 264-276 modified
Chemical type: Peptide from protein
Sequence: WESNGQPENNYK
Position: 260-271
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Positive
Host:  median: 54 years

Epitope: IgG1 265-277
Chemical type: Peptide from protein
Sequence: ESNGQPENNYKT
Position: 261-272
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1 265-277
Chemical type: Peptide from protein
Sequence: ESNGQPENNYKT
Position: 261-272
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Positive
Host:  median: 54 years

Epitope: IgG1 265-277 modified
Chemical type: Peptide from protein
Sequence: ESNGQPENNYKT
Position: 261-272
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Positive
Host:  median: 54 years

Epitope: IgG1 265-277 modified
Chemical type: Peptide from protein
Sequence: ESNGQPENNYKT
Position: 261-272
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1 266-278
Chemical type: Peptide from protein
Sequence: SNGQPENNYKTT
Position: 262-273
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1 266-278
Chemical type: Peptide from protein
Sequence: SNGQPENNYKTT
Position: 262-273
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Positive
Host:  median: 54 years

Epitope: IgG1-289B
Chemical type: Peptide from protein
Sequence: LYSKLTVDKSRWQQGNVFS
Position: 285-303
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1-289B
Chemical type: Peptide from protein
Sequence: LYSKLTVDKSRWQQGNVFS
Position: 285-303
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Positive
Host:  median: 54 years

Epitope: IgG1-289B
Chemical type: Peptide from protein
Sequence: LYSKLTVDKSRWQQGNVFS
Position: 285-303
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Positive

Epitope: IgG1 289-301
Chemical type: Peptide from protein
Sequence: LYSKLTVDKSRW
Position: 285-296
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1 289-301
Chemical type: Peptide from protein
Sequence: LYSKLTVDKSRW
Position: 285-296
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Negative
Host:  median: 54 years

Epitope: IgG1 290-302
Chemical type: Peptide from protein
Sequence: YSKLTVDKSRWQ
Position: 286-297
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1 290-302
Chemical type: Peptide from protein
Sequence: YSKLTVDKSRWQ
Position: 286-297
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Negative
Host:  median: 54 years

Epitope: IgG1 293-305
Chemical type: Peptide from protein
Sequence: LTVDKSRWQQGN
Position: 289-300
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1 293-305
Chemical type: Peptide from protein
Sequence: LTVDKSRWQQGN
Position: 289-300
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Negative
Host:  median: 54 years

Epitope: IgG1-319J
Chemical type: Peptide from protein
Sequence: YTQKSLSLSPGK
Position: 315-326
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1-319J
Chemical type: Peptide from protein
Sequence: YTQKSLSLSPGK
Position: 315-326
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Negative
Host:  median: 55 years

Epitope: IgG1-319J
Chemical type: Peptide from protein
Sequence: YTQKSLSLSPGK
Position: 315-326
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Positive
Host:  median: 54 years

Epitope: IgG1-319J
Chemical type: Peptide from protein
Sequence: YTQKSLSLSPGK
Position: 315-326
Source molecule (GenBank): P01859.2
Assay category: BCell
Result: Positive
Host:  median: 54 years