Reference: Salvatore Giovanni De-Simone; Larissa Rodrigues Gomes; Paloma Napoleão-Pêgo; Guilherme Curty Lechuga; Jorge Soares de Pina; Flavio Rocha da Silva. "Epitope Mapping of the Diphtheria Toxin and Development of an ELISA-Specific Diagnostic Assay." Vaccines (2021).

Epitope: A2
Chemical type: Peptide from protein
Sequence: MSRKLFASILIGALL
Position: 1-15
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Positive-Low

Epitope: A19
Chemical type: Peptide from protein
Sequence: DAAGYSVDNENPLSG
Position: 86-100
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Positive-High

Epitope: B10
Chemical type: Peptide from protein
Sequence: LSLPFAEGSSSVEYI
Position: 161-175
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Positive-High

Epitope: B11
Chemical type: Peptide from protein
Sequence: AEGSSSVEYINNWEQ
Position: 166-180
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Positive

Epitope: B21
Chemical type: Peptide from protein
Sequence: VRRSVGSSLSCINLD
Position: 216-230
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Negative

Epitope: D23
Chemical type: Peptide from protein
Sequence: LDVNKSKTHISVNGR
Position: 466-480
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Negative

Epitope: CB/DTx-2
Chemical type: Peptide from protein
Sequence: VDSSK
Position: 31-35
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Positive

Epitope: CB/DTx-10
Chemical type: Peptide from protein
Sequence: EHGPIKNKMSESPN
Position: 247-260
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Positive

Epitope: CB/DTx-19
Chemical type: Peptide from protein
Sequence: DGDVTFCRPKS
Position: 490-500
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Positive

Epitope: DTX-A3
Chemical type: Peptide from protein
Sequence: SSEKIHSNEISSDSI
Position: 520-534
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Positive

Epitope: DTX-A3
Chemical type: Peptide from protein
Sequence: SSEKIHSNEISSDSI
Position: 520-534
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Positive-High
Host:  6-16 years

Epitope: DTX-A3
Chemical type: Peptide from protein
Sequence: SSEKIHSNEISSDSI
Position: 520-534
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Positive

Epitope: DTX-A9
Chemical type: Peptide from protein
Sequence: SNEISSDSIGVLGYQ
Position: 526-540
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Positive

Epitope: DTX-A9
Chemical type: Peptide from protein
Sequence: SNEISSDSIGVLGYQ
Position: 526-540
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Positive-Low
Host:  6-16 years

Epitope: DTX-A9
Chemical type: Peptide from protein
Sequence: SNEISSDSIGVLGYQ
Position: 526-540
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Positive

Epitope: DTX-A12
Chemical type: Peptide from protein
Sequence: ISSDSIGVLGYQKTV
Position: 529-543
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Negative

Epitope: DTX-A12
Chemical type: Peptide from protein
Sequence: ISSDSIGVLGYQKTV
Position: 529-543
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Positive-Low
Host:  6-16 years

Epitope: DTX-A12
Chemical type: Peptide from protein
Sequence: ISSDSIGVLGYQKTV
Position: 529-543
Source molecule (GenBank): Q6NK15.1
Assay category: BCell
Result: Positive-Low