Reference: Annette Paschen; Mingxia Song; Simone Schenk; Jozef Janda; Xuan Duc Nguyen; Wolfram Osen; Dirk Schadendorf; Gernot Geginat. "Identification of a cross-reactive HLA-DRB1*0301-restricted CD4 T cell response directed against cholesterol-binding cytolysins from two different pathogens." Microbes and infection / Institut Pasteur (2006).

Epitope: LLO 16
Chemical type: Peptide from protein
Sequence: KHADEIDKYIQG
Position: 56-67
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 29
Chemical type: Peptide from protein
Sequence: AVTNVPPRKGYK
Position: 82-93
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 50
Chemical type: Peptide from protein
Sequence: LTYPGALVKANS
Position: 124-135
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 76
Chemical type: Peptide from protein
Sequence: SNVNNAVNTLVE
Position: 176-187
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 79
Chemical type: Peptide from protein
Sequence: VNTLVERWNEKY
Position: 182-193
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 90
Chemical type: Peptide from protein
Sequence: IDYDDEMAYSES
Position: 204-215
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Positive
MHC allele types: 57 167
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 97
Chemical type: Peptide from protein
Sequence: IAKFGTAFKAVN
Position: 218-229
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 103
Chemical type: Peptide from protein
Sequence: NSLNVNFGAISE
Position: 230-241
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 108
Chemical type: Peptide from protein
Sequence: SEGKMQEEVISF
Position: 240-251
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 119
Chemical type: Peptide from protein
Sequence: EPTRPSRFFGKA
Position: 262-273
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 131
Chemical type: Peptide from protein
Sequence: AENPPAYISSVA
Position: 286-297
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 153
Chemical type: Peptide from protein
Sequence: GDVELTNIIKNS
Position: 330-341
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 162
Chemical type: Peptide from protein
Sequence: YGGSAKDEVQII
Position: 348-359
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 165
Chemical type: Peptide from protein
Sequence: DEVQIIDGNLGD
Position: 354-365
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 182
Chemical type: Peptide from protein
Sequence: TTNFLKDNELAV
Position: 388-399
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 185
Chemical type: Peptide from protein
Sequence: DNELAVIKNNSE
Position: 394-405
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 186
Chemical type: Peptide from protein
Sequence: ELAVIKNNSEYI
Position: 396-407
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 190
Chemical type: Peptide from protein
Sequence: SEYIETTSKAYT
Position: 404-415
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 191
Chemical type: Peptide from protein
Sequence: YIETTSKAYTDG
Position: 406-417
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 194
Chemical type: Peptide from protein
Sequence: KAYTDGKINIDH
Position: 412-423
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 226
Chemical type: Peptide from protein
Sequence: NINVYAKECTGL
Position: 476-487
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 230
Chemical type: Peptide from protein
Sequence: CTGLAWEWWRTV
Position: 484-495
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: LLO 240
Chemical type: Peptide from protein
Sequence: VKNRNISIWGTT
Position: 504-515
Source molecule (GenBank): P13128.1
Assay category: TCell
Result: Negative
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PFO<sub>391-402</sub>
Chemical type: Peptide from protein
Sequence: KGKINLDHSGAY
Position: 391-402
Source molecule (GenBank): NP_561079.1
Assay category: TCell
Result: Positive
MHC allele types: 57 167
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Cell Line / Clone

Epitope: PFO<sub>391-402</sub>
Chemical type: Peptide from protein
Sequence: KGKINLDHSGAY
Position: 391-402
Source molecule (GenBank): NP_561079.1
Assay category: TCell
Result: Positive
MHC allele types: 57 167
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PFO<sub>391-402</sub>
Chemical type: Peptide from protein
Sequence: KGKINLDHSGAY
Position: 391-402
Source molecule (GenBank): NP_561079.1
Assay category: TCell
Result: Positive
MHC allele types: 57
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated