Reference: Anthony E Zamora; Jeremy Chase Crawford; E Kaitlynn Allen; Xi-Zhi J Guo; Jesse Bakke; Robert A Carter; Hossam A Abdelsamed; Ardiana Moustaki; Yongjin Li; Ti-Cheng Chang; Walid Awad; Mari H Dallas; Charles G Mullighan; James R Downing; Terrence L Geiger; Taosheng Chen; Douglas R Green; Benjamin A Youngblood; Jinghui Zhang; Paul G Thomas. "Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8<sup>+</sup> T cell responses." Science translational medicine (2019).

Epitope: SCD_E240K_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: YFWGKTFQNSVFVAT
Assay category: TCell
Result: Positive
MHC allele types: 1017 211 44 259 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SCD_E240K_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: YFWGKTFQNSVFVAT
Assay category: TCell
Result: Positive
MHC allele types: 1017 211 44 259 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SCD_E240K_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: YFWGKTFQNSVFVAT
Assay category: TCell
Result: Positive
MHC allele types: 1017 211 44 259 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139_A298T_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: FRTMAATTLKAFFKC
Assay category: TCell
Result: Negative
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GPR139_A298T_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: FRTMAATTLKAFFKC
Assay category: TCell
Result: Negative
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GPR139_A298T_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: FRTMAATTLKAFFKC
Assay category: TCell
Result: Negative
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GPR139_A298T_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: FRTMAATTLKAFFKC
Assay category: TCell
Result: Negative
Host:  adult
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GPR139_A298T_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: FRTMAATTLKAFFKC
Assay category: TCell
Result: Positive
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139_A298T_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: FRTMAATTLKAFFKC
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139_A298T_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: FRTMAATTLKAFFKC
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139_A298T_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: FRTMAATTLKAFFKC
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139_A298T_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: FRTMAATTLKAFFKC
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: GPR139_A298T_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: FRTMAATTLKAFFKC
Assay category: TCell
Result: Positive
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ITPR1_V656L mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: LIETKLLLSRFEFEG
Assay category: TCell
Result: Negative
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ITPR1_V656L mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: LIETKLLLSRFEFEG
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ITPR1_V656L mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: LIETKLLLSRFEFEG
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: BTBD16_V298M_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: IPTYETMMTFFKSFP
Assay category: TCell
Result: Positive
MHC allele types: 1017 211 44 259 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: BTBD16_V298M_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: IPTYETMMTFFKSFP
Assay category: TCell
Result: Positive
MHC allele types: 1017 211 44 259 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: BTBD16_V298M_var2 mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: IPTYETMMTFFKSFP
Assay category: TCell
Result: Negative
MHC allele types: 1017 211 44 259 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PIGZ_P455S mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: PVLPSTSTHYTLLFT
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PIGZ_P455S mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: PVLPSTSTHYTLLFT
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PIGZ_P455S mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: PVLPSTSTHYTLLFT
Assay category: TCell
Result: Positive
MHC allele types: 215 205 270 28 979 3
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ATP13A4_L109F mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: PDHPFMTDEEYIINR
Assay category: TCell
Result: Positive
MHC allele types: 200 32 195 932 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ATP13A4_L109F mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: PDHPFMTDEEYIINR
Assay category: TCell
Result: Positive
MHC allele types: 200 32 195 932 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: ATP13A4_L109F mutant 15-mer
Chemical type: Peptide, no natural source
Sequence: PDHPFMTDEEYIINR
Assay category: TCell
Result: Positive
MHC allele types: 200 32 195 932 629
Host:  child
Cell type: tumor infiltrating lymphocyte
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3(312−320)PAR
Chemical type: Peptide from protein
Sequence: TLDGFMMYL
Position: 312-320
Source molecule (GenBank): Q8N3E9.3
Assay category: TCell
Result: Positive-Low
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: PLCD3(310-319)MUT
Chemical type: Peptide, no natural source
Sequence: LMTLHGFMMY
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo

Epitope: SPATA5(807-815)MUT
Chemical type: Peptide, no natural source
Sequence: KLQFHCMPV
Assay category: TCell
Result: Positive
Host:  child
Cell type: T cell CD8+
Tissue: bone marrow
Culture conditions: Direct Ex Vivo