Reference: Siva Krishna Angalakurthi; David J Vance; Yinghui Rong; Chi My Thi Nguyen; Michael J Rudolph; David Volkin; C Russell Middaugh; David D Weis; Nicholas J Mantis. "A Collection of Single-Domain Antibodies that Crowd Ricin Toxin's Active Site." Antibodies (Basel, Switzerland) (2018).

Epitope: Epitope of V5A2, JIV-F6 and V1B10 VHHs on ricin RTA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y158, D159, R160, L161, E162, Q163, L164, A165, G166, N167, L168, R169, E170, I240, T241, L242, E243, N244, S245, F261, A262, S263, P264, I265, Q266, L267, Q268, R269, R270, N271, G272, S273, K274, F275, S276, V277, Y278, I284, P285, I286, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000314

Epitope: Epitope of V5A2, JIV-F6 and V1B10 VHHs on ricin RTA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y158, D159, R160, L161, E162, Q163, L164, A165, G166, N167, L168, R169, E170, I240, T241, L242, E243, N244, S245, F261, A262, S263, P264, I265, Q266, L267, Q268, R269, R270, N271, G272, S273, K274, F275, S276, V277, Y278, I284, P285, I286, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 82900.0

Epitope: Epitope of V5A2, JIV-F6 and V1B10 VHHs on ricin RTA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y158, D159, R160, L161, E162, Q163, L164, A165, G166, N167, L168, R169, E170, I240, T241, L242, E243, N244, S245, F261, A262, S263, P264, I265, Q266, L267, Q268, R269, R270, N271, G272, S273, K274, F275, S276, V277, Y278, I284, P285, I286, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000076

Epitope: Epitope of V5A2, JIV-F6 and V1B10 VHHs on ricin RTA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y158, D159, R160, L161, E162, Q163, L164, A165, G166, N167, L168, R169, E170, I240, T241, L242, E243, N244, S245, F261, A262, S263, P264, I265, Q266, L267, Q268, R269, R270, N271, G272, S273, K274, F275, S276, V277, Y278, I284, P285, I286, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.46

Epitope: Epitope of V5A2, JIV-F6 and V1B10 VHHs on ricin RTA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y158, D159, R160, L161, E162, Q163, L164, A165, G166, N167, L168, R169, E170, I240, T241, L242, E243, N244, S245, F261, A262, S263, P264, I265, Q266, L267, Q268, R269, R270, N271, G272, S273, K274, F275, S276, V277, Y278, I284, P285, I286, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 215000.0

Epitope: Epitope of V5A2, JIV-F6 and V1B10 VHHs on ricin RTA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y158, D159, R160, L161, E162, Q163, L164, A165, G166, N167, L168, R169, E170, I240, T241, L242, E243, N244, S245, F261, A262, S263, P264, I265, Q266, L267, Q268, R269, R270, N271, G272, S273, K274, F275, S276, V277, Y278, I284, P285, I286, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.917

Epitope: Epitope of V5A2, JIV-F6 and V1B10 VHHs on ricin RTA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y158, D159, R160, L161, E162, Q163, L164, A165, G166, N167, L168, R169, E170, I240, T241, L242, E243, N244, S245, F261, A262, S263, P264, I265, Q266, L267, Q268, R269, R270, N271, G272, S273, K274, F275, S276, V277, Y278, I284, P285, I286, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 194000.0

Epitope: Epitope of V5A2, JIV-F6 and V1B10 VHHs on ricin RTA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y158, D159, R160, L161, E162, Q163, L164, A165, G166, N167, L168, R169, E170, I240, T241, L242, E243, N244, S245, F261, A262, S263, P264, I265, Q266, L267, Q268, R269, R270, N271, G272, S273, K274, F275, S276, V277, Y278, I284, P285, I286, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000361

Epitope: Epitope of V5A2, JIV-F6 and V1B10 VHHs on ricin RTA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y158, D159, R160, L161, E162, Q163, L164, A165, G166, N167, L168, R169, E170, I240, T241, L242, E243, N244, S245, F261, A262, S263, P264, I265, Q266, L267, Q268, R269, R270, N271, G272, S273, K274, F275, S276, V277, Y278, I284, P285, I286, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.86

Epitope: Epitope of V5A2, JIV-F6 and V1B10 VHHs on ricin RTA
Chemical type: Discontinuous protein residues
Discontinuous residues: Y158, D159, R160, L161, E162, Q163, L164, A165, G166, N167, L168, R169, E170, I240, T241, L242, E243, N244, S245, F261, A262, S263, P264, I265, Q266, L267, Q268, R269, R270, N271, G272, S273, K274, F275, S276, V277, Y278, I284, P285, I286, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH V7H7 on ricin RTA
Chemical type: Discontinuous protein residues
Discontinuous residues: F127, F128, H129, P130,  D131, N132, Q133, E134, D135, A136, E137, A138, I139, T140, H141, L142, Y158, D159, R160, L161, I240, T241, L242, E243, N244, S245, W246, G247, R248, L249, S250, T251, A252, I284, P285, I286, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.507

Epitope: Epitope of VHH V7H7 on ricin RTA
Chemical type: Discontinuous protein residues
Discontinuous residues: F127, F128, H129, P130,  D131, N132, Q133, E134, D135, A136, E137, A138, I139, T140, H141, L142, Y158, D159, R160, L161, I240, T241, L242, E243, N244, S245, W246, G247, R248, L249, S250, T251, A252, I284, P285, I286, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000836

Epitope: Epitope of VHH V7H7 on ricin RTA
Chemical type: Discontinuous protein residues
Discontinuous residues: F127, F128, H129, P130,  D131, N132, Q133, E134, D135, A136, E137, A138, I139, T140, H141, L142, Y158, D159, R160, L161, I240, T241, L242, E243, N244, S245, W246, G247, R248, L249, S250, T251, A252, I284, P285, I286, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive
Quantitative measurement: 165000.0

Epitope: Epitope of VHH V7H7 on ricin RTA
Chemical type: Discontinuous protein residues
Discontinuous residues: F127, F128, H129, P130,  D131, N132, Q133, E134, D135, A136, E137, A138, I139, T140, H141, L142, Y158, D159, R160, L161, I240, T241, L242, E243, N244, S245, W246, G247, R248, L249, S250, T251, A252, I284, P285, I286, I287, A288, L289, M290
Source molecule (GenBank): P02879.1
Assay category: BCell
Result: Positive