Reference: Salvatore G De-Simone; Paloma Napoleão-Pêgo; Guilherme C Lechuga; João P R S Carvalho; Larissa R Gomes; Sergian V Cardozo; Carlos M Morel; David W Provance; Flavio R da Silva. "High-Throughput IgG Epitope Mapping of Tetanus Neurotoxin: Implications for Immunotherapy and Vaccine Design." Toxins (2023).

Epitope: TeNT 16-30_A4
Chemical type: Peptide from protein
Sequence: NDTIIMMEPPYCKGL
Position: 16-30
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 81-95_A17
Chemical type: Peptide from protein
Sequence: DSDKDRFLQTMVKLF
Position: 81-95
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 91-105_A19
Chemical type: Peptide from protein
Sequence: MVKLFNRIKNNVAGE
Position: 91-105
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 126-140_B2
Chemical type: Peptide from protein
Sequence: DKFDTNSNSVSFNLL
Position: 126-140
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 176-190_B12
Chemical type: Peptide from protein
Sequence: LRVDNKNYFPCRDGF
Position: 176-190
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 186-200_B14
Chemical type: Peptide from protein
Sequence: CRDGFGSIMQMAFCP
Position: 186-200
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 216-230_B20
Chemical type: Peptide from protein
Sequence: LTIGKSKYFQDPALL
Position: 216-230
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 226-240_B22
Chemical type: Peptide from protein
Sequence: DPALLLMHELIHVLH
Position: 226-240
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 256-270_C4
Chemical type: Peptide from protein
Sequence: KQEIYMQHTYPISAE
Position: 256-270
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 296-310_C12
Chemical type: Peptide from protein
Sequence: LNDYKAIANKLSQVT
Position: 296-310
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 346-360_C22
Chemical type: Peptide from protein
Sequence: KFQILYNSIMYGFTE
Position: 346-360
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 361-375_D1
Chemical type: Peptide from protein
Sequence: IELGKKFNIKTRLSY
Position: 361-375
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 391-405_D7
Chemical type: Peptide from protein
Sequence: DTIYNDTEGFNIESK
Position: 391-405
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 431-445_D15
Chemical type: Peptide from protein
Sequence: LVSKLIGLCKKIIPP
Position: 431-445
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 436-450_D16
Chemical type: Peptide from protein
Sequence: IGLCKKIIPPTNIRE
Position: 436-450
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 476-490_D24
Chemical type: Peptide from protein
Sequence: TFIAEKNSFSEEPFQ
Position: 476-490
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 491-505_E3
Chemical type: Peptide from protein
Sequence: DEIVSYNTKNKPLNF
Position: 491-505
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 496-510_E4
Chemical type: Peptide from protein
Sequence: YNTKNKPLNFNYSLD
Position: 496-510
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 501-515_E5
Chemical type: Peptide from protein
Sequence: KPLNFNYSLDKIIVD
Position: 501-515
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 601-615_F1
Chemical type: Peptide from protein
Sequence: SKVNQGAQGILFLQW
Position: 601-615
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 606-620_F2
Chemical type: Peptide from protein
Sequence: GAQGILFLQWVRDII
Position: 606-620
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 611-625_F3
Chemical type: Peptide from protein
Sequence: LFLQWVRDIIDDFTN
Position: 611-625
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 661-675_F13
Chemical type: Peptide from protein
Sequence: FIGALETTGVVLLLE
Position: 661-675
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 686-700_F18
Chemical type: Peptide from protein
Sequence: AALSIAESSTQKEKI
Position: 686-700
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 696-710_F20
Chemical type: Peptide from protein
Sequence: QKEKIIKTIDNFLEK
Position: 696-710
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 731-745_G3
Chemical type: Peptide from protein
Sequence: NTQFQKRSYQMYRSL
Position: 731-745
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 746-760_G6
Chemical type: Peptide from protein
Sequence: EYQVDAIKKIIDYEY
Position: 746-760
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 821-835_G21
Chemical type: Peptide from protein
Sequence: DTQSKNILMQYIKAN
Position: 821-835
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 841-855_H1
Chemical type: Peptide from protein
Sequence: ITELKKLESKINKVF
Position: 841-855
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 866-880_H6
Chemical type: Peptide from protein
Sequence: NLDCWVDNEEDIDVI
Position: 866-880
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 881-895_H9
Chemical type: Peptide from protein
Sequence: LKKSTILNLDINNDI
Position: 881-895
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 911-925_H15
Chemical type: Peptide from protein
Sequence: DAQLVPGINGKAIHL
Position: 911-925
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 916-930_H16
Chemical type: Peptide from protein
Sequence: PGINGKAIHLVNNES
Position: 916-930
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 921-935_H17
Chemical type: Peptide from protein
Sequence: KAIHLVNNESSEVIV
Position: 921-935
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 1011-1025_I11
Chemical type: Peptide from protein
Sequence: VRQITFRDLPDKFNA
Position: 1011-1025
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 1031-1045_I15
Chemical type: Peptide from protein
Sequence: WVFITITNDRLSSAN
Position: 1031-1045
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive
Host:  1-12 years

Epitope: TeNT 1131-1145_J11
Chemical type: Peptide from protein
Sequence: IPVASSSKDVQLKNI
Position: 1131-1145
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 1201-1215_K1
Chemical type: Peptide from protein
Sequence: SYNNNEHIVGYPKDG
Position: 1201-1215
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 1241-1255_K9
Chemical type: Peptide from protein
Sequence: EAVKLRDLKTYSVQL
Position: 1241-1255
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT 1296-1310_K20
Chemical type: Peptide from protein
Sequence: DKILGCDWYFVPTDE
Position: 1296-1310
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Negative
Host:  1-12 years

Epitope: TeNT_peptide 218
Chemical type: Peptide, no natural source
Sequence: GTVNTQFQYEYKIYS
Assay category: BCell
Result: Positive
Host:  1-9 years

Epitope: TeNT_peptide 218
Chemical type: Peptide, no natural source
Sequence: GTVNTQFQYEYKIYS
Assay category: BCell
Result: Positive-Low
Host:  10-13 years

Epitope: TeNT 570-579
Chemical type: Peptide from protein
Sequence: TTLQRITMT
Position: 571-579
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive-Low
Host:  1-12 years

Epitope: TeNT 1005-1019
Chemical type: Peptide from protein
Sequence: SAGEVRQITFRDLPD
Position: 1007-1021
Source molecule (GenBank): P04958.2
Assay category: BCell
Result: Positive-Low
Host:  1-12 years