Reference: Yu Zhao; Min Peng; Chengtao He; Min Li; Xuelian Han; Qiang Fu; Yandan Wu; Fangping Yue; Chunguang Yan; Guangyu Zhao; Chuanlai Shen. "Predominant T-cell epitopes of SARS-CoV-2 restricted by multiple prevalent HLA-B and HLA-C allotypes in Northeast Asia." Frontiers in immunology (2025).

Epitope: Y222
Chemical type: Peptide from protein
Sequence: RQGTDYKHW
Position: 293-301
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y222
Chemical type: Peptide from protein
Sequence: RQGTDYKHW
Position: 293-301
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y222
Chemical type: Peptide from protein
Sequence: RQGTDYKHW
Position: 293-301
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y222
Chemical type: Peptide from protein
Sequence: RQGTDYKHW
Position: 293-301
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: Y222
Chemical type: Peptide from protein
Sequence: RQGTDYKHW
Position: 293-301
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Y249
Chemical type: Peptide from protein
Sequence: STQDLFLPF
Position: 50-58
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y249
Chemical type: Peptide from protein
Sequence: STQDLFLPF
Position: 50-58
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y249
Chemical type: Peptide from protein
Sequence: STQDLFLPF
Position: 50-58
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y249
Chemical type: Peptide from protein
Sequence: STQDLFLPF
Position: 50-58
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y249
Chemical type: Peptide from protein
Sequence: STQDLFLPF
Position: 50-58
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: Y249
Chemical type: Peptide from protein
Sequence: STQDLFLPF
Position: 50-58
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: Y249
Chemical type: Peptide from protein
Sequence: STQDLFLPF
Position: 50-58
Source molecule (GenBank): P0DTC2.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Y71
Chemical type: Peptide from protein
Sequence: QEYADVFHL
Position: 5267-5275
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y71
Chemical type: Peptide from protein
Sequence: QEYADVFHL
Position: 5267-5275
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y71
Chemical type: Peptide from protein
Sequence: QEYADVFHL
Position: 5267-5275
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y71
Chemical type: Peptide from protein
Sequence: QEYADVFHL
Position: 5267-5275
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y71
Chemical type: Peptide from protein
Sequence: QEYADVFHL
Position: 5267-5275
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y71
Chemical type: Peptide from protein
Sequence: QEYADVFHL
Position: 5267-5275
Source molecule (GenBank): P0DTD1.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Y71
Chemical type: Peptide from protein
Sequence: QEYADVFHL
Position: 5267-5275
Source molecule (GenBank): P0DTD1.1
Assay category: MhcBinding
Result: Negative

Epitope: Y71
Chemical type: Peptide from protein
Sequence: QEYADVFHL
Position: 5267-5275
Source molecule (GenBank): P0DTD1.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: Y71
Chemical type: Peptide from protein
Sequence: QEYADVFHL
Position: 5267-5275
Source molecule (GenBank): P0DTD1.1
Assay category: MhcBinding
Result: Negative

Epitope: Y71
Chemical type: Peptide from protein
Sequence: QEYADVFHL
Position: 5267-5275
Source molecule (GenBank): P0DTD1.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Y71
Chemical type: Peptide from protein
Sequence: QEYADVFHL
Position: 5267-5275
Source molecule (GenBank): P0DTD1.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Y180
Chemical type: Peptide from protein
Sequence: LPAADLDDF
Position: 395-403
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y180
Chemical type: Peptide from protein
Sequence: LPAADLDDF
Position: 395-403
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y180
Chemical type: Peptide from protein
Sequence: LPAADLDDF
Position: 395-403
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y180
Chemical type: Peptide from protein
Sequence: LPAADLDDF
Position: 395-403
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y180
Chemical type: Peptide from protein
Sequence: LPAADLDDF
Position: 395-403
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y180
Chemical type: Peptide from protein
Sequence: LPAADLDDF
Position: 395-403
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: Y180
Chemical type: Peptide from protein
Sequence: LPAADLDDF
Position: 395-403
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Negative

Epitope: Y180
Chemical type: Peptide from protein
Sequence: LPAADLDDF
Position: 395-403
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: Y180
Chemical type: Peptide from protein
Sequence: LPAADLDDF
Position: 395-403
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: Y180
Chemical type: Peptide from protein
Sequence: LPAADLDDF
Position: 395-403
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Y180
Chemical type: Peptide from protein
Sequence: LPAADLDDF
Position: 395-403
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Negative

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-High

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Negative

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-High

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-Intermediate

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: Y62/M11
Chemical type: Peptide from protein
Sequence: KAYNVTQAF
Position: 266-274
Source molecule (GenBank): P0DTC9.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: M107
Chemical type: Peptide from protein
Sequence: YFIASFRLF
Position: 95-103
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M107
Chemical type: Peptide from protein
Sequence: YFIASFRLF
Position: 95-103
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M107
Chemical type: Peptide from protein
Sequence: YFIASFRLF
Position: 95-103
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M107
Chemical type: Peptide from protein
Sequence: YFIASFRLF
Position: 95-103
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M107
Chemical type: Peptide from protein
Sequence: YFIASFRLF
Position: 95-103
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M107
Chemical type: Peptide from protein
Sequence: YFIASFRLF
Position: 95-103
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Positive-High

Epitope: M107
Chemical type: Peptide from protein
Sequence: YFIASFRLF
Position: 95-103
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Negative

Epitope: M107
Chemical type: Peptide from protein
Sequence: YFIASFRLF
Position: 95-103
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Negative

Epitope: M107
Chemical type: Peptide from protein
Sequence: YFIASFRLF
Position: 95-103
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: M107
Chemical type: Peptide from protein
Sequence: YFIASFRLF
Position: 95-103
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: M107
Chemical type: Peptide from protein
Sequence: YFIASFRLF
Position: 95-103
Source molecule (GenBank): P0DTC5.1
Assay category: MhcBinding
Result: Positive-Intermediate