Reference: Bianca R Mothé; Barbara S Stewart; Carla Oseroff; Huynh-Hoa Bui; Stephanie Stogiera; Zacarias Garcia; Courtney Dow; Maria Pilar Rodriguez-Carreno; Maya Kotturi; Valerie Pasquetto; Jason Botten; Shane Crotty; Edith Janssen; Michael J Buchmeier; Alessandro Sette. "Chronic lymphocytic choriomeningitis virus infection actively down-regulates CD4+ T cell responses directed against a broad range of epitopes." Journal of immunology (Baltimore, Md. : 1950) (2007).

Epitope: GP<sub>1-15</sub>
Chemical type: Peptide from protein
Sequence: MGQIVTMFEALPHII
Position: 1-15
Source molecule (GenBank): AAX49341.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GP<sub>11-25</sub>
Chemical type: Peptide from protein
Sequence: LPHIIDEVINIVIIV
Position: 11-25
Source molecule (GenBank): AAX49341.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GP<sub>36-50</sub>
Chemical type: Peptide from protein
Sequence: YNFATCGIFALISFL
Position: 36-50
Source molecule (GenBank): AAX49341.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GP<sub>156-170</sub>
Chemical type: Peptide from protein
Sequence: KAVSCDFNNGITIQY
Position: 156-170
Source molecule (GenBank): AAX49341.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GP<sub>196-210</sub>
Chemical type: Peptide from protein
Sequence: RTAFGGKYMRSGWGW
Position: 196-210
Source molecule (GenBank): AAX49341.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GP<sub>216-230</sub>
Chemical type: Peptide from protein
Sequence: KTTWCSQTSYQYLII
Position: 216-230
Source molecule (GenBank): AAX49341.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GP<sub>291-305</sub>
Chemical type: Peptide from protein
Sequence: ILAAELKCFGNTAVA
Position: 291-305
Source molecule (GenBank): AAX49341.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GP<sub>301-315</sub>
Chemical type: Peptide from protein
Sequence: NTAVAKCNVNHDEEF
Position: 301-315
Source molecule (GenBank): AAX49341.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: NP<sub>61-75</sub>
Chemical type: Peptide from protein
Sequence: DKDLQRLRSLNQTVH
Position: 61-75
Source molecule (GenBank): AAX49342.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: NP<sub>151-165</sub>
Chemical type: Peptide from protein
Sequence: QGASGVVRVWDVKDS
Position: 151-165
Source molecule (GenBank): AAX49342.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: NP<sub>216-230</sub>
Chemical type: Peptide from protein
Sequence: ERLKDKHPVLGVITE
Position: 216-230
Source molecule (GenBank): AAX49342.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: NP<sub>431-445</sub>
Chemical type: Peptide from protein
Sequence: LFNAQPGLTSSVIGA
Position: 431-445
Source molecule (GenBank): AAX49342.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: NP<sub>446-460</sub>
Chemical type: Peptide from protein
Sequence: LPQGMVLSCQGSDDI
Position: 446-460
Source molecule (GenBank): AAX49342.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: NP<sub>511-525</sub>
Chemical type: Peptide from protein
Sequence: KKEITPHCALMDCII
Position: 511-525
Source molecule (GenBank): AAX49342.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>16-30</sub>
Chemical type: Peptide from protein
Sequence: IEQDERLSRQKLNFL
Position: 16-30
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>26-40</sub>
Chemical type: Peptide from protein
Sequence: KLNFLGQREPRMVLI
Position: 26-40
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>61-75</sub>
Chemical type: Peptide from protein
Sequence: THNHDDKSVETILVE
Position: 61-75
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>111-125</sub>
Chemical type: Peptide from protein
Sequence: SFEKKFIEDTNKLAC
Position: 111-125
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>116-130</sub>
Chemical type: Peptide from protein
Sequence: FIEDTNKLACIREDL
Position: 116-130
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>151-165</sub>
Chemical type: Peptide from protein
Sequence: FMPEWANFKFRDLLF
Position: 151-165
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>196-210</sub>
Chemical type: Peptide from protein
Sequence: KRSGMDSMKILKDAR
Position: 196-210
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>271-285</sub>
Chemical type: Peptide from protein
Sequence: SELYENLADSDDILT
Position: 271-285
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>371-385</sub>
Chemical type: Peptide from protein
Sequence: YSSVNDRLVSFHSTK
Position: 371-385
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>396-410</sub>
Chemical type: Peptide from protein
Sequence: KKSKVFRKVSFEELF
Position: 396-410
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>626-640</sub>
Chemical type: Peptide from protein
Sequence: QKQVQSVRYLVMAIV
Position: 626-640
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>666-680</sub>
Chemical type: Peptide from protein
Sequence: KLLRFLIKTIFGTGE
Position: 666-680
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>711-725</sub>
Chemical type: Peptide from protein
Sequence: DQIKCFEKFFEPKSQ
Position: 711-725
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>731-745</sub>
Chemical type: Peptide from protein
Sequence: NPKEAITPEEECVFY
Position: 731-745
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>741-755</sub>
Chemical type: Peptide from protein
Sequence: ECVFYEQMKRFTSKE
Position: 741-755
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>746-760</sub>
Chemical type: Peptide from protein
Sequence: EQMKRFTSKEIDCQH
Position: 746-760
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>751-765</sub>
Chemical type: Peptide from protein
Sequence: FTSKEIDCQHTTPGV
Position: 751-765
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>781-795</sub>
Chemical type: Peptide from protein
Sequence: TLIFKGEKKLNSLDP
Position: 781-795
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>821-835</sub>
Chemical type: Peptide from protein
Sequence: GERLLEYDFNKLLVS
Position: 821-835
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>956-970</sub>
Chemical type: Peptide from protein
Sequence: SFHLVEDFDPSCLTN
Position: 956-970
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>976-990</sub>
Chemical type: Peptide from protein
Sequence: ICEAVEGSTELSPLY
Position: 976-990
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1031-1045</sub>
Chemical type: Peptide from protein
Sequence: ANAYSGKYRHMQRQG
Position: 1031-1045
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1066-1080</sub>
Chemical type: Peptide from protein
Sequence: SNSESLSKALSLTKC
Position: 1066-1080
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1071-1085</sub>
Chemical type: Peptide from protein
Sequence: LSKALSLTKCMSAAL
Position: 1071-1085
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1141-1155</sub>
Chemical type: Peptide from protein
Sequence: DYFESFSSFFSGSCL
Position: 1141-1155
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1156-1170</sub>
Chemical type: Peptide from protein
Sequence: NNDKEFENAILSMTI
Position: 1156-1170
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1181-1195</sub>
Chemical type: Peptide from protein
Sequence: MDHSKWGPMMCPFLF
Position: 1181-1195
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1251-1265</sub>
Chemical type: Peptide from protein
Sequence: LRGSETTVTERIFRQ
Position: 1251-1265
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1261-1275</sub>
Chemical type: Peptide from protein
Sequence: RIFRQYFEMGIVPSH
Position: 1261-1275
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1266-1280</sub>
Chemical type: Peptide from protein
Sequence: YFEMGIVPSHISSLI
Position: 1266-1280
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1311-1325</sub>
Chemical type: Peptide from protein
Sequence: GERPEAYTSSDDQIT
Position: 1311-1325
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1346-1360</sub>
Chemical type: Peptide from protein
Sequence: LEFQSHLSGLLNKFI
Position: 1346-1360
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1441-1455</sub>
Chemical type: Peptide from protein
Sequence: ANFPLDPFLLNTNTD
Position: 1441-1455
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1566-1580</sub>
Chemical type: Peptide from protein
Sequence: RIPSLIKTLQNKLCS
Position: 1566-1580
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1611-1625</sub>
Chemical type: Peptide from protein
Sequence: CKTLGSRCVRNKNRE
Position: 1611-1625
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1896-1910</sub>
Chemical type: Peptide from protein
Sequence: MFRNDLQFGFGWFSY
Position: 1896-1910
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1936-1950</sub>
Chemical type: Peptide from protein
Sequence: LKDLWDYMLNYTKGV
Position: 1936-1950
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1941-1955</sub>
Chemical type: Peptide from protein
Sequence: DYMLNYTKGVLEFSI
Position: 1941-1955
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1951-1965</sub>
Chemical type: Peptide from protein
Sequence: LEFSISVDFTHNQNN
Position: 1951-1965
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1961-1975</sub>
Chemical type: Peptide from protein
Sequence: HNQNNTDCLRKFSLI
Position: 1961-1975
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1971-1985</sub>
Chemical type: Peptide from protein
Sequence: KFSLIFLVRCQLQNP
Position: 1971-1985
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1991-2005</sub>
Chemical type: Peptide from protein
Sequence: LSCSHLFKGEIDRRM
Position: 1991-2005
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>1996-2010</sub>
Chemical type: Peptide from protein
Sequence: LFKGEIDRRMLDECL
Position: 1996-2010
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>2061-2075</sub>
Chemical type: Peptide from protein
Sequence: IRSIDFERVGPEWEP
Position: 2061-2075
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>2086-2100</sub>
Chemical type: Peptide from protein
Sequence: FEGRNLVQNIIVKLE
Position: 2086-2100
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>2126-2140</sub>
Chemical type: Peptide from protein
Sequence: LHRFRTGEHLLGSEI
Position: 2126-2140
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: L<sub>2186-2200</sub>
Chemical type: Peptide from protein
Sequence: VGGRFRLKGRSCDDW
Position: 2186-2200
Source molecule (GenBank): AAX49344.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Z<sub>1-15</sub>
Chemical type: Peptide from protein
Sequence: MGQGKSREEKGTNST
Position: 1-15
Source molecule (GenBank): AAX49343.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo