Reference: Leonard Moise; Chang Song; William D Martin; Ryan Tassone; Anne S De Groot; David W Scott. "Effect of HLA DR epitope de-immunization of Factor VIII in vitro and in vivo." Clinical immunology (Orlando, Fla.) (2012).

Epitope: 2231_MOD1
Chemical type: Peptide, no natural source
Sequence: QVDGQKTMKVTGVTTQGVKSL
Assay category: TCell
Result: Positive-Low
Host:  6-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 2231_MOD1
Chemical type: Peptide, no natural source
Sequence: QVDGQKTMKVTGVTTQGVKSL
Assay category: TCell
Result: Negative
Host:  6-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 2231_MOD1
Chemical type: Peptide, no natural source
Sequence: QVDGQKTMKVTGVTTQGVKSL
Assay category: MhcBinding
Result: Positive

Epitope: 2231_MOD1
Chemical type: Peptide, no natural source
Sequence: QVDGQKTMKVTGVTTQGVKSL
Assay category: MhcBinding
Result: Positive-Low

Epitope: 2231_MOD1
Chemical type: Peptide, no natural source
Sequence: QVDGQKTMKVTGVTTQGVKSL
Assay category: MhcBinding
Result: Positive-Low

Epitope: 2231_MOD1
Chemical type: Peptide, no natural source
Sequence: QVDGQKTMKVTGVTTQGVKSL
Assay category: MhcBinding
Result: Negative

Epitope: 2231_MOD1
Chemical type: Peptide, no natural source
Sequence: QVDGQKTMKVTGVTTQGVKSL
Assay category: MhcBinding
Result: Positive-Low

Epitope: 2254_ORG
Chemical type: Peptide from protein
Sequence: SMYVKEFLISSSQDGH
Position: 2273-2288
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Host:  6-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 2254_ORG
Chemical type: Peptide from protein
Sequence: SMYVKEFLISSSQDGH
Position: 2273-2288
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Host:  6-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 2254_ORG
Chemical type: Peptide from protein
Sequence: SMYVKEFLISSSQDGH
Position: 2273-2288
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Host:  6-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 2254_ORG
Chemical type: Peptide from protein
Sequence: SMYVKEFLISSSQDGH
Position: 2273-2288
Source molecule (GenBank): P00451.1
Assay category: MhcBinding
Result: Positive-High

Epitope: 2254_ORG
Chemical type: Peptide from protein
Sequence: SMYVKEFLISSSQDGH
Position: 2273-2288
Source molecule (GenBank): P00451.1
Assay category: MhcBinding
Result: Positive

Epitope: 2254_ORG
Chemical type: Peptide from protein
Sequence: SMYVKEFLISSSQDGH
Position: 2273-2288
Source molecule (GenBank): P00451.1
Assay category: MhcBinding
Result: Positive-High

Epitope: 2254_ORG
Chemical type: Peptide from protein
Sequence: SMYVKEFLISSSQDGH
Position: 2273-2288
Source molecule (GenBank): P00451.1
Assay category: MhcBinding
Result: Negative

Epitope: 2254_ORG
Chemical type: Peptide from protein
Sequence: SMYVKEFLISSSQDGH
Position: 2273-2288
Source molecule (GenBank): P00451.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: 2299_MOD1
Chemical type: Peptide, no natural source
Sequence: PPLLTRYGRIHPQSWVHQI
Assay category: MhcBinding
Result: Positive-High

Epitope: 2299_MOD1
Chemical type: Peptide, no natural source
Sequence: PPLLTRYGRIHPQSWVHQI
Assay category: MhcBinding
Result: Positive

Epitope: 2299_MOD1
Chemical type: Peptide, no natural source
Sequence: PPLLTRYGRIHPQSWVHQI
Assay category: MhcBinding
Result: Positive-Low

Epitope: 2299_MOD1
Chemical type: Peptide, no natural source
Sequence: PPLLTRYGRIHPQSWVHQI
Assay category: MhcBinding
Result: Negative

Epitope: 2299_MOD1
Chemical type: Peptide, no natural source
Sequence: PPLLTRYGRIHPQSWVHQI
Assay category: MhcBinding
Result: Positive-Low

Epitope: 2310_MOD1
Chemical type: Peptide, no natural source
Sequence: PQSSVHQIALRMEVLGCEAQD
Assay category: TCell
Result: Positive
Host:  6-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 2310_MOD1
Chemical type: Peptide, no natural source
Sequence: PQSSVHQIALRMEVLGCEAQD
Assay category: TCell
Result: Positive
Host:  6-10 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 2310_MOD1
Chemical type: Peptide, no natural source
Sequence: PQSSVHQIALRMEVLGCEAQD
Assay category: MhcBinding
Result: Positive

Epitope: 2310_MOD1
Chemical type: Peptide, no natural source
Sequence: PQSSVHQIALRMEVLGCEAQD
Assay category: MhcBinding
Result: Positive-High

Epitope: 2310_MOD1
Chemical type: Peptide, no natural source
Sequence: PQSSVHQIALRMEVLGCEAQD
Assay category: MhcBinding
Result: Positive-High

Epitope: 2310_MOD1
Chemical type: Peptide, no natural source
Sequence: PQSSVHQIALRMEVLGCEAQD
Assay category: MhcBinding
Result: Positive

Epitope: 2310_MOD1
Chemical type: Peptide, no natural source
Sequence: PQSSVHQIALRMEVLGCEAQD
Assay category: MhcBinding
Result: Positive