Reference: Pooja Vir; Ahmad Faisal Karim; Devi Gunasekera; Allen I Stering; Kenneth Lieuw; Shannon L Meeks; Kathleen P Pratt. "T cells from individuals with and without hemophilia A respond to the same epitopes in factor VIII." Journal of thrombosis and haemostasis : JTH (2025).

Epitope: A1-9
Chemical type: Peptide from protein
Sequence: RVPKSFPFNTSVVYK
Position: 52-66
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A1-47
Chemical type: Peptide from protein
Sequence: AKEKTQTLHKFILLF
Position: 204-218
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A1-89
Chemical type: Peptide from protein
Sequence: SEMDVVRFDDDNSPS
Position: 372-386
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A2-10
Chemical type: Peptide from protein
Sequence: SQYLNNGPQRIGRKY
Position: 428-442
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A2-15
Chemical type: Peptide from protein
Sequence: MAYTDETFKTREAIQ
Position: 448-462
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A2-23
Chemical type: Peptide from protein
Sequence: LLIIFKNQASRPYNI
Position: 480-494
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A2-23
Chemical type: Peptide from protein
Sequence: LLIIFKNQASRPYNI
Position: 480-494
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: A2-90
Chemical type: Peptide from protein
Sequence: YLLSKNNAIEPRSFS
Position: 748-762
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A2-90
Chemical type: Peptide from protein
Sequence: YLLSKNNAIEPRSFS
Position: 748-762
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: A3-27
Chemical type: Peptide from protein
Sequence: NEHLGLLGPYIRAEV
Position: 1772-1786
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: A3-27
Chemical type: Peptide from protein
Sequence: NEHLGLLGPYIRAEV
Position: 1772-1786
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
MHC allele types: 436
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A3-27
Chemical type: Peptide from protein
Sequence: NEHLGLLGPYIRAEV
Position: 1772-1786
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
MHC allele types: 436 52
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: A3-27
Chemical type: Peptide from protein
Sequence: NEHLGLLGPYIRAEV
Position: 1772-1786
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
MHC allele types: 436
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C1-21
Chemical type: Peptide from protein
Sequence: IKTQGARQKFSSLYI
Position: 2103-2117
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C1-22
Chemical type: Peptide from protein
Sequence: GARQKFSSLYISQFI
Position: 2107-2121
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: C1-22
Chemical type: Peptide from protein
Sequence: GARQKFSSLYISQFI
Position: 2107-2121
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Positive
MHC allele types: 413
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C1-33
Chemical type: Peptide from protein
Sequence: SSGIKHNIFNPPIIA
Position: 2151-2165
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C2-7
Chemical type: Peptide from protein
Sequence: SYFTNMFATWSPSKA
Position: 2213-2227
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C2-15
Chemical type: Peptide from protein
Sequence: PKEWLQVDFQKTMKV
Position: 2245-2259
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C2-19
Chemical type: Peptide from protein
Sequence: GVTTQGVKSLLTSMY
Position: 2261-2275
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C2-33
Chemical type: Peptide from protein
Sequence: DPPLLTRYLRIHPQS
Position: 2317-2331
Source molecule (GenBank): P00451.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C2-42
Chemical type: Peptide from protein
Sequence: VKVTGVTTQGVKSLL
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated