Reference: Tobias Deuse; Xiaomeng Hu; Sean Agbor-Enoh; Martina Koch; Matthew H Spitzer; Alessia Gravina; Malik Alawi; Argit Marishta; Bjoern Peters; Zeynep Kosaloglu-Yalcin; Yanqin Yang; Raja Rajalingam; Dong Wang; Bjoern Nashan; Rainer Kiefmann; Hermann Reichenspurner; Hannah Valantine; Irving L Weissman; Sonja Schrepfer. "De novo mutations in mitochondrial DNA of iPSCs produce immunogenic neoepitopes in mice and humans." Nature biotechnology (2019).

Epitope: B/c mt-Co3 SNP 6
Chemical type: Peptide from protein
Sequence: HFVDVIWLFLYVSIYWWGS
Position: 243-261
Source molecule (GenBank): ABK79164.1
Assay category: TCell
Result: Negative
Host: M 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: B/c mt-Co3 SNP 6
Chemical type: Peptide from protein
Sequence: HFVDVIWLFLYVSIYWWGS
Position: 243-261
Source molecule (GenBank): ABK79164.1
Assay category: TCell
Result: Negative
Host: M 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: B/c mt-Co3 SNP 6
Chemical type: Peptide from protein
Sequence: HFVDVIWLFLYVSIYWWGS
Position: 243-261
Source molecule (GenBank): ABK79164.1
Assay category: TCell
Result: Negative
Host: M 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: B/c mt-Co3 SNP 6
Chemical type: Peptide from protein
Sequence: HFVDVIWLFLYVSIYWWGS
Position: 243-261
Source molecule (GenBank): ABK79164.1
Assay category: TCell
Result: Negative
Host: M 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MOLF/EiJ-Cytb SNP6
Chemical type: Peptide from protein
Sequence: GVLALVLSILILALMPFLHT
Position: 290-309
Source molecule (GenBank): AMM76090.1
Assay category: TCell
Result: Negative
Host: M 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MOLF/EiJ-Cytb SNP6
Chemical type: Peptide from protein
Sequence: GVLALVLSILILALMPFLHT
Position: 290-309
Source molecule (GenBank): AMM76090.1
Assay category: TCell
Result: Negative
Host: M 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: GLLLFLLSLMTLTLFSPDLL
Chemical type: Peptide from protein
Sequence: GLLLFLLSLMTLTLFSPDLL
Position: 231-250
Source molecule (GenBank): P00156.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GLLLFLLSLMTLTLFSPDLL
Chemical type: Peptide from protein
Sequence: GLLLFLLSLMTLTLFSPDLL
Position: 231-250
Source molecule (GenBank): P00156.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: ISPSLDVSLLLTLSILSIMA
Chemical type: Peptide from protein
Sequence: ISPSLDVSLLLTLSILSIMA
Position: 145-164
Source molecule (GenBank): A0A023Q8P7.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: ISPSLDVSLLLTLSILSIMA
Chemical type: Peptide from protein
Sequence: ISPSLDVSLLLTLSILSIMA
Position: 145-164
Source molecule (GenBank): A0A023Q8P7.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NAGTYLLFYTLVGSLPLLIA
Chemical type: Peptide from protein
Sequence: NAGTYLLFYTLVGSLPLLIA
Position: 144-163
Source molecule (GenBank): C9D5S4.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GGQPVGSYPFTIIGQVASVL
Chemical type: Peptide from protein
Sequence: GGQPVGSYPFTIIGQVASVL
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: SKQMMTMHNTKGRTWSLMLV
Chemical type: Peptide from protein
Sequence: SKQMMTMHNTKGRTWSLMLV
Position: 54-73
Source molecule (GenBank): P00846.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: SKQMMTMHNTKGRTWSLMLV
Chemical type: Peptide from protein
Sequence: SKQMMTMHNTKGRTWSLMLV
Position: 54-73
Source molecule (GenBank): P00846.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MYQISPSLNVSLLLILSILS
Chemical type: Peptide from protein
Sequence: MYQISPSLNVSLLLILSILS
Position: 142-161
Source molecule (GenBank): H9LQQ4.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PYYTIKDALGLLLFILSLMT
Chemical type: Peptide from protein
Sequence: PYYTIKDALGLLLFILSLMT
Position: 222-241
Source molecule (GenBank): B7U870.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PYYTIKDALGLLLFILSLMT
Chemical type: Peptide from protein
Sequence: PYYTIKDALGLLLFILSLMT
Position: 222-241
Source molecule (GenBank): B7U870.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LTWIGGQPVSYPFTVIGQVA
Chemical type: Peptide from protein
Sequence: LTWIGGQPVSYPFTVIGQVA
Position: 335-354
Source molecule (GenBank): F2YTI2.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MVVAGVFLLIRFHPLAENSP
Chemical type: Peptide from protein
Sequence: MVVAGVFLLIRFHPLAENSP
Position: 252-271
Source molecule (GenBank): A0A343RM17.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: WINTTTHSLIISIIPLLFFN
Chemical type: Peptide from protein
Sequence: WINTTTHSLIISIIPLLFFN
Position: 24-43
Source molecule (GenBank): P03905.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LPAAVLIILFPPLLTPTSKY
Chemical type: Peptide from protein
Sequence: LPAAVLIILFPPLLTPTSKY
Position: 17-36
Source molecule (GenBank): E9LCR9.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PVSYPFTIIGQVASVLYFTT
Chemical type: Peptide from protein
Sequence: PVSYPFTIIGQVASVLYFTT
Position: 342-361
Source molecule (GenBank): P00156.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LITAVLLLLSLPVLAAGITM
Chemical type: Peptide from protein
Sequence: LITAVLLLLSLPVLAAGITM
Position: 189-208
Source molecule (GenBank): P00395.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LITAVLLLLSLPVLAAGITM
Chemical type: Peptide from protein
Sequence: LITAVLLLLSLPVLAAGITM
Position: 189-208
Source molecule (GenBank): P00395.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MTNTTNQYSSLMIMMAMAMK
Chemical type: Peptide from protein
Sequence: MTNTTNQYSSLMIMMAMAMK
Position: 86-105
Source molecule (GenBank): P03891.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: SFLYSKTWNIGIILLLATMA
Chemical type: Peptide from protein
Sequence: SFLYSKTWNIGIILLLATMA
Position: 106-125
Source molecule (GenBank): A0A343FI06.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: MSFWLLPPSFLLLLASSMVE
Chemical type: Peptide from protein
Sequence: MSFWLLPPSFLLLLASSMVE
Position: 100-119
Source molecule (GenBank): BBA31677.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MSFWLLPPSFLLLLASSMVE
Chemical type: Peptide from protein
Sequence: MSFWLLPPSFLLLLASSMVE
Position: 100-119
Source molecule (GenBank): BBA31677.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MSFWLLPPSFLLLLASSMVE
Chemical type: Peptide from protein
Sequence: MSFWLLPPSFLLLLASSMVE
Position: 100-119
Source molecule (GenBank): BBA31677.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MSFWLLPPSFLLLLASSMVE
Chemical type: Peptide from protein
Sequence: MSFWLLPPSFLLLLASSMVE
Position: 100-119
Source molecule (GenBank): BBA31677.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: INLYTVIFINILLSLTLILV
Chemical type: Peptide, no natural source
Sequence: INLYTVIFINILLSLTLILV
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: INLYTVIFINILLSLTLILV
Chemical type: Peptide, no natural source
Sequence: INLYTVIFINILLSLTLILV
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MPQLDTSTWFITIISSMITL
Chemical type: Peptide, no natural source
Sequence: MPQLDTSTWFITIISSMITL
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: MPQLDTSTWFITIISSMITL
Chemical type: Peptide, no natural source
Sequence: MPQLDTSTWFITIISSMITL
Assay category: TCell
Result: Positive
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PLTTPPLMLTTWLLPLTIMA
Chemical type: Peptide, no natural source
Sequence: PLTTPPLMLTTWLLPLTIMA
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLTTPPLMLTTWLLPLTIMA
Chemical type: Peptide, no natural source
Sequence: PLTTPPLMLTTWLLPLTIMA
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo