Reference: Peter Orth; Li Xiao; Lorraine D Hernandez; Paul Reichert; Payal R Sheth; Maribel Beaumont; Xiaoyu Yang; Nicholas Murgolo; Grigori Ermakov; Edward DiNunzio; Fred Racine; Jerzy Karczewski; Susan Secore; Richard N Ingram; Todd Mayhood; Corey Strickland; Alex G Therien. "Mechanism of action and epitopes of Clostridium difficile toxin B-neutralizing antibody bezlotoxumab revealed by X-ray crystallography." The Journal of biological chemistry (2014).

Epitope: Bezlotoxumab Fab1 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: E1878, Y1887, Q1890, S1900, T1901, E1902, D1903, F1905, D1939, N1941, R1943, G1944, V1946, E1947, P1960, E1961
Source molecule (GenBank): P18177.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.019

Epitope: Bezlotoxumab Fab1 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: E1878, Y1887, Q1890, S1900, T1901, E1902, D1903, F1905, D1939, N1941, R1943, G1944, V1946, E1947, P1960, E1961
Source molecule (GenBank): P18177.3
Assay category: BCell
Result: Positive
Quantitative measurement: 2.89

Epitope: Bezlotoxumab Fab1 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: E1878, Y1887, Q1890, S1900, T1901, E1902, D1903, F1905, D1939, N1941, R1943, G1944, V1946, E1947, P1960, E1961
Source molecule (GenBank): P18177.3
Assay category: BCell
Result: Positive

Epitope: Bezlotoxumab Fab1 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: E1878, Y1887, Q1890, S1900, T1901, E1902, D1903, F1905, D1939, N1941, R1943, G1944, V1946, E1947, P1960, E1961
Source molecule (GenBank): P18177.3
Assay category: BCell
Result: Positive

Epitope: Bezlotoxumab Fab1 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: E1878, Y1887, Q1890, S1900, T1901, E1902, D1903, F1905, D1939, N1941, R1943, G1944, V1946, E1947, P1960, E1961
Source molecule (GenBank): P18177.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.37

Epitope: Bezlotoxumab Fab1 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: E1878, Y1887, Q1890, S1900, T1901, E1902, D1903, F1905, D1939, N1941, R1943, G1944, V1946, E1947, P1960, E1961
Source molecule (GenBank): P18177.3
Assay category: BCell
Result: Positive
Quantitative measurement: 15700000

Epitope: Bezlotoxumab Fab1 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: E1878, Y1887, Q1890, S1900, T1901, E1902, D1903, F1905, D1939, N1941, R1943, G1944, V1946, E1947, P1960, E1961
Source molecule (GenBank): P18177.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00559

Epitope: Bezlotoxumab Fab1 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: E1878, Y1887, Q1890, S1900, T1901, E1902, D1903, F1905, D1939, N1941, R1943, G1944, V1946, E1947, P1960, E1961
Source molecule (GenBank): P18177.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0000283

Epitope: Bezlotoxumab Fab1 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: E1878, Y1887, Q1890, S1900, T1901, E1902, D1903, F1905, D1939, N1941, R1943, G1944, V1946, E1947, P1960, E1961
Source molecule (GenBank): P18177.3
Assay category: BCell
Result: Positive
Quantitative measurement: 1520000.0

Epitope: Bezlotoxumab Fab1 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: E1878, Y1887, Q1890, S1900, T1901, E1902, D1903, F1905, D1939, N1941, R1943, G1944, V1946, E1947, P1960, E1961
Source molecule (GenBank): P18177.3
Assay category: BCell
Result: Positive

Epitope: Bezlotoxumab Fab1 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: E1878, Y1887, Q1890, S1900, T1901, E1902, D1903, F1905, D1939, N1941, R1943, G1944, V1946, E1947, P1960, E1961
Source molecule (GenBank): P18177.3
Assay category: BCell
Result: Positive