Reference: Eddie A James; Laurel Gillette; Ivana Durinovic-Bello; Cate Speake; George P Bondinas; Antonis K Moustakas; Carla J Greenbaum; George K Papadopoulos; William W Kwok. "DRB4*01:01 Has a Distinct Motif and Presents a Proinsulin Epitope That Is Recognized in Subjects with Type 1 Diabetes." Journal of immunology (Baltimore, Md. : 1950) (2018).

Epitope: TT 803-834 818R
Chemical type: Peptide, no natural source
Sequence: SFLVNQMINEAKKQLR
Assay category: MhcBinding
Result: Positive-High

Epitope: TT 803-815 P1L-V
Chemical type: Peptide, no natural source
Sequence: SFVVNQMINEAKK
Assay category: MhcBinding
Result: Positive-High

Epitope: TT 803-815 P1L-A
Chemical type: Peptide, no natural source
Sequence: SFAVNQMINEAKK
Assay category: MhcBinding
Result: Positive-Low

Epitope: TT 803-815 P4Q-D
Chemical type: Peptide, no natural source
Sequence: SFLVNDMINEAKK
Assay category: MhcBinding
Result: Positive-Low

Epitope: TT 803-815 P6I-K
Chemical type: Peptide, no natural source
Sequence: SFLVNQMKNEAKK
Assay category: MhcBinding
Result: Positive-Low

Epitope: TT 803-815 P7N-M
Chemical type: Peptide, no natural source
Sequence: SFLVNQMIMEAKK
Assay category: MhcBinding
Result: Positive

Epitope: TT 803-815 P7N-K
Chemical type: Peptide, no natural source
Sequence: SFLVNQMIKEAKK
Assay category: MhcBinding
Result: Positive-Low

Epitope: TT 803-815 P7N-H
Chemical type: Peptide, no natural source
Sequence: SFLVNQMIHEAKK
Assay category: MhcBinding
Result: Positive-Low

Epitope: GAD65 265-284
Chemical type: Peptide from protein
Sequence: KGMAALPRLIAFTSEHSHFS
Position: 280-299
Source molecule (GenBank): CAA49554.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GAD65 265-284
Chemical type: Peptide from protein
Sequence: KGMAALPRLIAFTSEHSHFS
Position: 280-299
Source molecule (GenBank): CAA49554.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 10000.0

Epitope: GAD65 353-372
Chemical type: Peptide from protein
Sequence: ICKKYKIWMHVDAAWGGGLL
Position: 368-387
Source molecule (GenBank): CAA49554.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GAD65 353-372
Chemical type: Peptide from protein
Sequence: ICKKYKIWMHVDAAWGGGLL
Position: 368-387
Source molecule (GenBank): CAA49554.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GAD65 353-372
Chemical type: Peptide from protein
Sequence: ICKKYKIWMHVDAAWGGGLL
Position: 368-387
Source molecule (GenBank): CAA49554.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 900.0

Epitope: GAD65 513-532
Chemical type: Peptide from protein
Sequence: LRTLEDNEERMSRLSKVAPV
Position: 528-547
Source molecule (GenBank): CAA49554.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GAD65 513-532
Chemical type: Peptide from protein
Sequence: LRTLEDNEERMSRLSKVAPV
Position: 528-547
Source molecule (GenBank): CAA49554.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 5900.0

Epitope: GAD65 529-548
Chemical type: Peptide from protein
Sequence: VAPVIKARMMEYGTTMVSYQ
Position: 544-563
Source molecule (GenBank): CAA49554.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GAD65 529-548
Chemical type: Peptide from protein
Sequence: VAPVIKARMMEYGTTMVSYQ
Position: 544-563
Source molecule (GenBank): CAA49554.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GAD65 529-548
Chemical type: Peptide from protein
Sequence: VAPVIKARMMEYGTTMVSYQ
Position: 544-563
Source molecule (GenBank): CAA49554.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2800.0

Epitope: GAD65 553-572
Chemical type: Peptide from protein
Sequence: KVNFFRMVISNPAATHQDID
Position: 568-587
Source molecule (GenBank): CAA49554.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GAD65 553-572
Chemical type: Peptide from protein
Sequence: KVNFFRMVISNPAATHQDID
Position: 568-587
Source molecule (GenBank): CAA49554.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: GAD65 553-572
Chemical type: Peptide from protein
Sequence: KVNFFRMVISNPAATHQDID
Position: 568-587
Source molecule (GenBank): CAA49554.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 7800.0