Reference: Sky T H Ng; Michael J Price; Naomi Richardson; Maher Nawaf; Alastair Copland; Heather B Streeter; Parth Narendran; David C Wraith. "Preclinical Development of a Tolerogenic Peptide From Glutamate Decarboxylase as a Candidate for Antigen-Specific Immunotherapy in Type 1 Diabetes." Diabetes (2025).

Epitope: P10Sol
Chemical type: Peptide from protein
Sequence: WKLSGVERA
Position: 213-221
Source molecule (GenBank): Q9UGI5.1
Assay category: TCell
Result: Positive-High
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: P10Sol
Chemical type: Peptide from protein
Sequence: WKLSGVERA
Position: 213-221
Source molecule (GenBank): Q9UGI5.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: P10Sol
Chemical type: Peptide from protein
Sequence: WKLSGVERA
Position: 213-221
Source molecule (GenBank): Q9UGI5.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: P10Sol
Chemical type: Peptide from protein
Sequence: WKLSGVERA
Position: 213-221
Source molecule (GenBank): Q9UGI5.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: P10Sol
Chemical type: Peptide from protein
Sequence: WKLSGVERA
Position: 213-221
Source molecule (GenBank): Q9UGI5.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: P10Sol
Chemical type: Peptide from protein
Sequence: WKLSGVERA
Position: 213-221
Source molecule (GenBank): Q9UGI5.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Cell Line / Clone (Hybridoma)

Epitope: P10Sol
Chemical type: Peptide from protein
Sequence: WKLSGVERA
Position: 213-221
Source molecule (GenBank): Q9UGI5.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: P10Sol
Chemical type: Peptide from protein
Sequence: WKLSGVERA
Position: 213-221
Source molecule (GenBank): Q9UGI5.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: P10Sol
Chemical type: Peptide from protein
Sequence: WKLSGVERA
Position: 213-221
Source molecule (GenBank): Q9UGI5.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: P10Sol
Chemical type: Peptide from protein
Sequence: WKLSGVERA
Position: 213-221
Source molecule (GenBank): Q9UGI5.1
Assay category: TCell
Result: Positive
MHC allele types: 57 63 420 425 408 414 52 413 419 407
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P10Sol
Chemical type: Peptide from protein
Sequence: WKLSGVERA
Position: 213-221
Source molecule (GenBank): Q9UGI5.1
Assay category: TCell
Result: Positive-High
MHC allele types: 57 63 420 425 408 414 52 413 419 407
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: P10Sol
Chemical type: Peptide from protein
Sequence: WKLSGVERA
Position: 213-221
Source molecule (GenBank): Q9UGI5.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo