Reference: José Afonso Guerra-Assunção; Ruairi McErlean; Katie Townsend; Selin Cankat; Leonhard M Flaxl; Shengwei Jamie Tian; Thomas R Turner; Neema P Mayor; Judith Breuer; Leo Swadling; David M Lowe. "Extensive evolution and T cell escape by SARS-CoV-2 in a 2.5-year persistent infection of an immunocompromised host." iScience (2026).

Epitope: S22
Chemical type: Peptide from protein
Sequence: KSWMESEFRVY
Position: 150-160
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
MHC allele types: 436 425 587 323 75 67
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: S22
Chemical type: Peptide from protein
Sequence: KSWMESEFRVY
Position: 150-160
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 143 776 255 260 12796 1027
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: S22
Chemical type: Peptide from protein
Sequence: KSWMESEFRVY
Position: 150-160
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 436 425 587 323 75 67
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: S22
Chemical type: Peptide from protein
Sequence: KSWMESEFRVY
Position: 150-160
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: S22
Chemical type: Peptide from protein
Sequence: KSWMESEFRVY
Position: 150-160
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
MHC allele types: 436 425 587 323 75 67
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: S22
Chemical type: Peptide from protein
Sequence: KSWMESEFRVY
Position: 150-160
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 436 425 587 323 75 67
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: S22
Chemical type: Peptide from protein
Sequence: KSWMESEFRVY
Position: 150-160
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
MHC allele types: 143 776 255 260 12796 1027
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP2
Chemical type: Peptide from protein
Sequence: TSDLATNNLVVMAY
Position: 587-600
Source molecule (GenBank): P0DTC1.1
Assay category: TCell
Result: Negative
MHC allele types: 436 425 587 323 75 67
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP2
Chemical type: Peptide from protein
Sequence: TSDLATNNLVVMAY
Position: 587-600
Source molecule (GenBank): P0DTC1.1
Assay category: TCell
Result: Negative
MHC allele types: 436 425 587 323 75 67
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP2
Chemical type: Peptide from protein
Sequence: TSDLATNNLVVMAY
Position: 587-600
Source molecule (GenBank): P0DTC1.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 436 425 587 323 75 67
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP2
Chemical type: Peptide from protein
Sequence: TSDLATNNLVVMAY
Position: 587-600
Source molecule (GenBank): P0DTC1.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 436 425 587 323 75 67
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP2
Chemical type: Peptide from protein
Sequence: TSDLATNNLVVMAY
Position: 587-600
Source molecule (GenBank): P0DTC1.1
Assay category: TCell
Result: Positive
MHC allele types: 143 776 255 260 12796 1027
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP2
Chemical type: Peptide from protein
Sequence: TSDLATNNLVVMAY
Position: 587-600
Source molecule (GenBank): P0DTC1.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 143 776 255 260 12796 1027
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP2
Chemical type: Peptide from protein
Sequence: TSDLATNNLVVMAY
Position: 587-600
Source molecule (GenBank): P0DTC1.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 143 776 255 260 12796 1027
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: NSP2
Chemical type: Peptide from protein
Sequence: TSDLATNNLVVMAY
Position: 587-600
Source molecule (GenBank): P0DTC1.1
Assay category: TCell
Result: Positive
MHC allele types: 143 776 255 260 12796 1027
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: S22v
Chemical type: Peptide from protein
Sequence: KSWMESELRVY
Position: 146-156
Source molecule (GenBank): WVH11482.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 436 425 587 323 75 67
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: S22v
Chemical type: Peptide from protein
Sequence: KSWMESELRVY
Position: 146-156
Source molecule (GenBank): WVH11482.1
Assay category: TCell
Result: Positive-Low
MHC allele types: 436 425 587 323 75 67
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: S22v
Chemical type: Peptide from protein
Sequence: KSWMESELRVY
Position: 146-156
Source molecule (GenBank): WVH11482.1
Assay category: TCell
Result: Negative
MHC allele types: 436 425 587 323 75 67
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: S22v
Chemical type: Peptide from protein
Sequence: KSWMESELRVY
Position: 146-156
Source molecule (GenBank): WVH11482.1
Assay category: TCell
Result: Negative
MHC allele types: 436 425 587 323 75 67
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated