Reference: Annette von Delft; Isla S Humphreys; Anthony Brown; Katja Pfafferott; Michaela Lucas; Paul Klenerman; Georg M Lauer; Andrea L Cox; Silvana Gaudieri; Eleanor Barnes. "The broad assessment of HCV genotypes 1 and 3 antigenic targets reveals limited cross-reactivity with implications for vaccine design." Gut (2016).

Epitope: HCV 3a NS3 (1379-1388)
Chemical type: Peptide from protein
Sequence: IPFYGKAIPI
Position: 1379-1388
Source molecule (GenBank): ACZ60108.1
Assay category: TCell
Result: Positive
Host:  18-49 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 3 core  (137-153)
Chemical type: Peptide from protein
Sequence: IPLVGAPVGGVARALAH
Position: 137-153
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1b E2 (603-618)
Chemical type: Peptide from protein
Sequence: LTPRCLVDYPYRLWHY
Position: 603-618
Source molecule (GenBank): AAA45721.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1a NS3 (1033-1055)
Chemical type: Peptide from protein
Sequence: AQQTRGLLGCIITSLTGRDKNQV
Position: 1033-1055
Source molecule (GenBank): ABV46054.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1b NS3 (1033-1055)
Chemical type: Peptide from protein
Sequence: SQQTRGVLGCIITSLTGRDKNQV
Position: 1033-1055
Source molecule (GenBank): AAC15722.1
Assay category: TCell
Result: Positive-Low
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1b NS5B (2591-2606)
Chemical type: Peptide from protein
Sequence: KMALYDVVSTLPQAVM
Position: 2591-2606
Source molecule (GenBank): AAA45721.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1 Core (143-158)
Chemical type: Peptide from protein
Sequence: IPLVGAPVGGVARALAH
Position: 137-153
Source molecule (GenBank): ABD97104.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1 Core (143-158)
Chemical type: Peptide from protein
Sequence: IPLVGAPVGGVARALAH
Position: 137-153
Source molecule (GenBank): ABD97104.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1 Core (143-158)
Chemical type: Peptide from protein
Sequence: IPLVGAPVGGVARALAH
Position: 137-153
Source molecule (GenBank): ABD97104.1
Assay category: TCell
Result: Negative
Host:  18-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1 NS3 (1379-1387)
Chemical type: Peptide from protein
Sequence: IPFYGKAIPI
Position: 1373-1382
Source molecule (GenBank): AAA45721.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1 NS3 (1379-1387)
Chemical type: Peptide from protein
Sequence: IPFYGKAIPI
Position: 1373-1382
Source molecule (GenBank): AAA45721.1
Assay category: TCell
Result: Positive
Host:  18-49 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1 NS3 (1379-1387)
Chemical type: Peptide from protein
Sequence: IPFYGKAIPI
Position: 1373-1382
Source molecule (GenBank): AAA45721.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1 NS5b (2893-2908)
Chemical type: Peptide from protein
Sequence: IIERLHGLSAFTLHSY
Position: 2881-2896
Source molecule (GenBank): AAC15722.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1 NS5b (2893-2908)
Chemical type: Peptide from protein
Sequence: IIERLHGLSAFTLHSY
Position: 2881-2896
Source molecule (GenBank): AAC15722.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 1 NS5b (2893-2908)
Chemical type: Peptide from protein
Sequence: IIERLHGLSAFTLHSY
Position: 2881-2896
Source molecule (GenBank): AAC15722.1
Assay category: TCell
Result: Negative
Host:  18-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 3a NS2 (70-79)
Chemical type: Peptide from protein
Sequence: LLHPSLVFDI
Position: 70-79
Source molecule (GenBank): ACX44379.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 3 NS3 v (1443-1451)
Chemical type: Peptide from protein
Sequence: ATDALMTGF
Position: 1442-1450
Source molecule (GenBank): ACZ60108.1
Assay category: TCell
Result: Positive
Host:  18-49 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 3 NS3 v (1443-1451)
Chemical type: Peptide from protein
Sequence: ATDALMTGF
Position: 1442-1450
Source molecule (GenBank): ACZ60108.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 3 NS3 v (1443-1451)
Chemical type: Peptide from protein
Sequence: ATDALMTGF
Position: 1442-1450
Source molecule (GenBank): ACZ60108.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 3a NS5A (2030-2047)
Chemical type: Peptide from protein
Sequence: GVMSTRCPCGASIAGHVK
Position: 2029-2046
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HCV 3a NS5B (2893-2908)
Chemical type: Peptide from protein
Sequence: IIERLHGLSAFTLHSY
Position: 2892-2907
Source molecule (GenBank): ACZ60102.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo