Reference: Sebastian Kreiter; Mathias Vormehr; Niels van de Roemer; Mustafa Diken; Martin Löwer; Jan Diekmann; Sebastian Boegel; Barbara Schrörs; Fulvia Vascotto; John C Castle; Arbel D Tadmor; Stephen P Schoenberger; Christoph Huber; Özlem Türeci; Ugur Sahin. "Mutant MHC class II epitopes drive therapeutic immune responses to cancer." Nature (2015).

Epitope: B16-M20
Chemical type: Peptide, no natural source
Sequence: FRRKAFLHWYTGEAMDEMEFTEAESNM
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: B16-M24
Chemical type: Peptide, no natural source
Sequence: TAVITPPTTTTKKARVSTPKPATPSTD
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: B16-M45
Chemical type: Peptide, no natural source
Sequence: ECRITSNFVIPSEYWVEEKEEKQKLIQ
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CT26-M19
Chemical type: Peptide, no natural source
Sequence: QAIVRGCSMPGPWRSGRLLVSRRWSVE
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CT26-M19
Chemical type: Peptide, no natural source
Sequence: QAIVRGCSMPGPWRSGRLLVSRRWSVE
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CT26-M20
Chemical type: Peptide, no natural source
Sequence: PLLPFYPPDEALEIGLELNSSALPPTE
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CT26-M20
Chemical type: Peptide, no natural source
Sequence: PLLPFYPPDEALEIGLELNSSALPPTE
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CT26-M27
Chemical type: Peptide, no natural source
Sequence: EHIHRAGGLFVADAIQVGFGRIGKHFW
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CT26-M27
Chemical type: Peptide, no natural source
Sequence: EHIHRAGGLFVADAIQVGFGRIGKHFW
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 4T1-M16
Chemical type: Peptide, no natural source
Sequence: ELAWEIDRKVLHQNRLQRTPIKLQCFA
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 4T1-M26
Chemical type: Peptide, no natural source
Sequence: AVKEEDSLHWQRPEDVQKVKALSFYQP
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 4T1-M35
Chemical type: Peptide, no natural source
Sequence: KELLQFKKLKKQNLQQMQAESGFVQHV
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: 4T1-M40
Chemical type: Peptide, no natural source
Sequence: RVEKLQLESELNESRTECITATSQMTA
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CT26-ME3
Chemical type: Peptide, no natural source
Sequence: DGQLELLAQGALDNALSSMGALHALRP
Assay category: TCell
Result: Positive-Low
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CT26-ME5
Chemical type: Peptide, no natural source
Sequence: QDINDNNPSFPTGKMKLEISEALAPGT
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CT26-ME6
Chemical type: Peptide, no natural source
Sequence: SDPRAAYFRQAENDMYIRMALLATVLG
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: CT26-ME9
Chemical type: Peptide, no natural source
Sequence: KARLKSKDVKLAEAHQQECCQKFEQLS
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo