Reference: Mariarosaria Miranda; Bjarke Endel Hansen; Batoul Wehbi; Valeria Porcheddu; Floris P J Van Alphen; Paul Kaijen; Karin Fijnvandraat; Sebastien Lacroix-Desmazes; Maartje Van den Biggelaar; Bernard Maillere; Jan Voorberg; Educ Consortium. "FVIII peptides presented on HLA-DP and identification of an A3 domain peptide binding with high affinity to the commonly expressed HLA-DP4." Haematologica (2025).

Epitope: FVIII P10
Chemical type: Peptide from protein
Sequence: EFTDHLFNIAKPRPP
Position: 72-86
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: FVIII P103
Chemical type: Peptide from protein
Sequence: SMYVKEFLISSSQ
Position: 2273-2285
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: FVIII P120
Chemical type: Peptide from protein
Sequence: LGPYIRAEVEDNIM
Position: 1778-1791
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: FVIII P121
Chemical type: Peptide from protein
Sequence: AEVEDNIMVTFRNQASRPYSF
Position: 1784-1804
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: FVIII P121
Chemical type: Peptide from protein
Sequence: AEVEDNIMVTFRNQASRPYSF
Position: 1784-1804
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: FVIII P13
Chemical type: Peptide from protein
Sequence: YDTVVITLKNMASHPV
Position: 100-115
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: FVIII P2
Chemical type: Peptide from protein
Sequence: LFVEFTDHLFNIAKPRPP
Position: 69-86
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: FVIII P28
Chemical type: Peptide from protein
Sequence: GEVGDTLLIIFKNQASRPYN
Position: 474-493
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: FVIII P30
Chemical type: Peptide from protein
Sequence: VGDTLLIIFKNQASRPYN
Position: 476-493
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: FVIII P32
Chemical type: Peptide from protein
Sequence: YPHGITDVRPLYSR
Position: 495-508
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: FVIII P35
Chemical type: Peptide from protein
Sequence: DISAYLLSKNNAIEPR
Position: 744-759
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: FVIII P38
Chemical type: Peptide from protein
Sequence: GPSPKQLVSLGPEKSVEGQ
Position: 1142-1160
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: FVIII P39
Chemical type: Peptide from protein
Sequence: LGPEKSVEGQNFLSEKNK
Position: 1151-1168
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: FVIII P44
Chemical type: Peptide from protein
Sequence: SFQKKTRHYFIAAVERLWDYGMSSSPHVL
Position: 1709-1737
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: FVIII P68
Chemical type: Peptide from protein
Sequence: VRKKEEYKMALYNLYPGVFE
Position: 1984-2003
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: FVIII P68
Chemical type: Peptide from protein
Sequence: VRKKEEYKMALYNLYPGVFE
Position: 1984-2003
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: FVIII P76
Chemical type: Peptide from protein
Sequence: KEEYKMALYNLYPG
Position: 1987-2000
Source molecule (GenBank): P00451.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P4MS
Chemical type: Peptide from protein
Sequence: GEVGDTLLIIFKNQASRPYNIYPHGI
Position: 474-499
Source molecule (GenBank): P00451.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 4675.0

Epitope: P8MS
Chemical type: Peptide from protein
Sequence: AEVEDNIMVTFRNQASRPYSF
Position: 1784-1804
Source molecule (GenBank): P00451.1
Assay category: MhcBinding
Result: Negative