Reference: Tanner Michaelis; Cecilia S Lindestam Arlehamn; Emil Johansson; April Frazier; James D Berry; Merit Cudkowicz; Namita A Goyal; Christina Fournier; Allison Snyder; Justin Y Kwan; Jody Crook; Elizabeth J Phillips; Simon A Mallal; John Ravits; Karen S Marder; John Sidney; David Sulzer; Alessandro Sette. "Autoimmune response to C9orf72 protein in amyotrophic lateral sclerosis." Nature (2025).

Epitope: C9orf72_6-20
Chemical type: Peptide from protein
Sequence: PPPSPAVAKTEIALS
Position: 6-20
Source molecule (GenBank): Q96LT7.2
Assay category: TCell
Result: Negative
Host:  45-81 years
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C9orf72_61-75
Chemical type: Peptide from protein
Sequence: FLANHTLNGEILRNA
Position: 61-75
Source molecule (GenBank): Q96LT7.2
Assay category: TCell
Result: Positive
Host:  45-81 years
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C9orf72_101-115
Chemical type: Peptide from protein
Sequence: GNWNGDRSTYGLSII
Position: 101-115
Source molecule (GenBank): Q96LT7.2
Assay category: TCell
Result: Negative
Host:  45-81 years
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C9orf72_276-290
Chemical type: Peptide from protein
Sequence: SGLFVQGLLKDSTGS
Position: 276-290
Source molecule (GenBank): Q96LT7.2
Assay category: TCell
Result: Positive
Host:  45-81 years
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C9orf72_321-335
Chemical type: Peptide from protein
Sequence: CHEHIYNQRRYMRSE
Position: 321-335
Source molecule (GenBank): Q96LT7.2
Assay category: TCell
Result: Positive
Host:  45-81 years
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C9orf72_346-360
Chemical type: Peptide from protein
Sequence: EDMAQDTIIYTDESF
Position: 346-360
Source molecule (GenBank): Q96LT7.2
Assay category: TCell
Result: Negative
Host:  45-81 years
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C9orf72_361-375
Chemical type: Peptide from protein
Sequence: TPDLNIFQDVLHRDT
Position: 361-375
Source molecule (GenBank): Q96LT7.2
Assay category: TCell
Result: Positive
Host:  45-81 years
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C9orf72_391-405
Chemical type: Peptide from protein
Sequence: LSLRSTFLAQFLLVL
Position: 391-405
Source molecule (GenBank): Q96LT7.2
Assay category: TCell
Result: Positive
Host:  45-81 years
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C9orf72_406-420
Chemical type: Peptide from protein
Sequence: HRKALTLIKYIEDDT
Position: 406-420
Source molecule (GenBank): Q96LT7.2
Assay category: TCell
Result: Positive
Host:  45-81 years
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C9orf72_456-470
Chemical type: Peptide from protein
Sequence: KPGLHSFIFGRPFYT
Position: 456-470
Source molecule (GenBank): Q96LT7.2
Assay category: TCell
Result: Positive
Host:  45-81 years
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: C9orf72_466-480
Chemical type: Peptide from protein
Sequence: RPFYTSVQERDVLMT
Position: 466-480
Source molecule (GenBank): Q96LT7.2
Assay category: TCell
Result: Positive
Host:  45-81 years
Cell type: T cell
Tissue: blood
Culture conditions: Short Term Restimulated