Reference: Ronit Mazor; Masanori Onda; Dong Park; Selamawit Addissie; Laiman Xiang; Jingli Zhang; Raffit Hassan; Ira Pastan. "Dual B- and T-cell de-immunization of recombinant immunotoxin targeting mesothelin with high cytotoxic activity." Oncotarget (2016).

Epitope: P13
Chemical type: Peptide from protein
Sequence: GYPVQRLVALYLAAR
Position: 300-314
Source molecule (GenBank): WP_044305324.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P23
Chemical type: Peptide from protein
Sequence: SPGSGGDLGEAIREQ
Position: 330-344
Source molecule (GenBank): WP_044305324.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P34
Chemical type: Peptide from protein
Sequence: VRQGTGNDEAGAANG
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P36
Chemical type: Peptide from protein
Sequence: NDEAGAANGPADSGD
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P53
Chemical type: Peptide from protein
Sequence: QAHRQLEERGYVFVG
Position: 436-450
Source molecule (GenBank): WP_044305324.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P61
Chemical type: Peptide from protein
Sequence: QSIVFGGVRARSQDL
Position: 460-474
Source molecule (GenBank): WP_044305324.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P74
Chemical type: Peptide from protein
Sequence: PDARGRIRNGALLRV
Position: 499-513
Source molecule (GenBank): WP_044305324.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P75
Chemical type: Peptide from protein
Sequence: RGRIRNGALLRVYVP
Position: 502-516
Source molecule (GenBank): WP_044305324.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P80
Chemical type: Peptide from protein
Sequence: RSSLPGFYRTSLTLA
Position: 530-544
Source molecule (GenBank): WP_039027124.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P84
Chemical type: Peptide from protein
Sequence: TLAAPEAAGEVERLI
Position: 529-543
Source molecule (GenBank): WP_044305324.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: P105
Chemical type: Peptide from protein
Sequence: GDLDPSSIPDKEQAI
Position: 592-606
Source molecule (GenBank): WP_044305324.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LMB-T20 P54
Chemical type: Peptide, no natural source
Sequence: AQLEERGYVFVGYHG
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LMB-T20 P56
Chemical type: Peptide, no natural source
Sequence: GYVFVGYHGTALEAA
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LMB-T20 P74
Chemical type: Peptide, no natural source
Sequence: PDARGRIANGALLRV
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LMB-T20 P94
Chemical type: Peptide, no natural source
Sequence: EEGGREETILGWPLA
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: LMB-T14 P66
Chemical type: Peptide, no natural source
Sequence: AAIWAGFYIAGDPAH
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated