Reference: Gulnoz S Dolimbek; Behzod Z Dolimbek; K Roger Aoki; M Zouhair Atassi. "Mapping of the antibody and T cell recognition profiles of the HN domain (residues 449-859) of the heavy chain of botulinum neurotoxin A in two high-responder mouse strains." Immunological investigations (2005).

Epitope: N8
Chemical type: Peptide from protein
Sequence: KYTMFHYLRAQEFEHGKSR
Position: 547-565
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-9 weeks

Epitope: N8
Chemical type: Peptide from protein
Sequence: KYTMFHYLRAQEFEHGKSR
Position: 547-565
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-9 weeks

Epitope: N8
Chemical type: Peptide from protein
Sequence: KYTMFHYLRAQEFEHGKSR
Position: 547-565
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-9 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: N8
Chemical type: Peptide from protein
Sequence: KYTMFHYLRAQEFEHGKSR
Position: 547-565
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-9 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: N18
Chemical type: Peptide from protein
Sequence: NKVLTVQTIDNALSKRNEK
Position: 687-705
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-9 weeks

Epitope: N18
Chemical type: Peptide from protein
Sequence: NKVLTVQTIDNALSKRNEK
Position: 687-705
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-9 weeks

Epitope: N18
Chemical type: Peptide from protein
Sequence: NKVLTVQTIDNALSKRNEK
Position: 687-705
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-9 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: N18
Chemical type: Peptide from protein
Sequence: NKVLTVQTIDNALSKRNEK
Position: 687-705
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-9 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: N27
Chemical type: Peptide from protein
Sequence: ASLKDALLKYIYDNRGTLI
Position: 813-831
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-9 weeks

Epitope: N27
Chemical type: Peptide from protein
Sequence: ASLKDALLKYIYDNRGTLI
Position: 813-831
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-9 weeks

Epitope: N27
Chemical type: Peptide from protein
Sequence: ASLKDALLKYIYDNRGTLI
Position: 813-831
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-9 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: N27
Chemical type: Peptide from protein
Sequence: ASLKDALLKYIYDNRGTLI
Position: 813-831
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-9 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: C2
Chemical type: Peptide from protein
Sequence: YIKNIINTSILNLRYESNH
Position: 869-887
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-9 weeks

Epitope: C2
Chemical type: Peptide from protein
Sequence: YIKNIINTSILNLRYESNH
Position: 869-887
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-9 weeks

Epitope: C2
Chemical type: Peptide from protein
Sequence: YIKNIINTSILNLRYESNH
Position: 869-887
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-9 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: C2
Chemical type: Peptide from protein
Sequence: YIKNIINTSILNLRYESNH
Position: 869-887
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-9 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: C8
Chemical type: Peptide from protein
Sequence: FNSISLNNEYTIINCMENN
Position: 953-971
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-9 weeks

Epitope: C8
Chemical type: Peptide from protein
Sequence: FNSISLNNEYTIINCMENN
Position: 953-971
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-9 weeks

Epitope: C8
Chemical type: Peptide from protein
Sequence: FNSISLNNEYTIINCMENN
Position: 953-971
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-9 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: C8
Chemical type: Peptide from protein
Sequence: FNSISLNNEYTIINCMENN
Position: 953-971
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-9 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: C14
Chemical type: Peptide from protein
Sequence: DQKPISNLGNIHASNNIMF
Position: 1037-1055
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-9 weeks

Epitope: C14
Chemical type: Peptide from protein
Sequence: DQKPISNLGNIHASNNIMF
Position: 1037-1055
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-9 weeks

Epitope: C14
Chemical type: Peptide from protein
Sequence: DQKPISNLGNIHASNNIMF
Position: 1037-1055
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-9 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: C14
Chemical type: Peptide from protein
Sequence: DQKPISNLGNIHASNNIMF
Position: 1037-1055
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-9 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: C28
Chemical type: Peptide from protein
Sequence: NKCKMNLQDNNGNDIGFIG
Position: 1233-1251
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-9 weeks

Epitope: C28
Chemical type: Peptide from protein
Sequence: NKCKMNLQDNNGNDIGFIG
Position: 1233-1251
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-9 weeks

Epitope: C28
Chemical type: Peptide from protein
Sequence: NKCKMNLQDNNGNDIGFIG
Position: 1233-1251
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Positive
Host: F 7-9 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: C28
Chemical type: Peptide from protein
Sequence: NKCKMNLQDNNGNDIGFIG
Position: 1233-1251
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-9 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: C30
Chemical type: Peptide from protein
Sequence: LVASNWYNRQIERSSRTLG
Position: 1261-1279
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Positive
Host: F 7-9 weeks

Epitope: C30
Chemical type: Peptide from protein
Sequence: LVASNWYNRQIERSSRTLG
Position: 1261-1279
Source molecule (GenBank): P10845.4
Assay category: BCell
Result: Negative
Host: F 7-9 weeks

Epitope: C30
Chemical type: Peptide from protein
Sequence: LVASNWYNRQIERSSRTLG
Position: 1261-1279
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-9 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: C30
Chemical type: Peptide from protein
Sequence: LVASNWYNRQIERSSRTLG
Position: 1261-1279
Source molecule (GenBank): P10845.4
Assay category: TCell
Result: Negative
Host: F 7-9 weeks
Cell type: lymphocyte
Tissue: lymph node
Culture conditions: Direct Ex Vivo