Reference: Janine Ehser; Martin Holdener; Selina Christen; Monika Bayer; Josef M Pfeilschifter; Edith Hintermann; Dimitrios Bogdanos; Urs Christen. "Molecular mimicry rather than identity breaks T-cell tolerance in the CYP2D6 mouse model for human autoimmune hepatitis." Journal of autoimmunity (2013).

Epitope: hCyp2D6 P17
Chemical type: Peptide from protein
Sequence: REQRRFSVSTLRNLGLGKKS
Position: 129-148
Source molecule (GenBank): ADF36437.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: hCyp2D6 P17
Chemical type: Peptide from protein
Sequence: REQRRFSVSTLRNLGLGKKS
Position: 129-148
Source molecule (GenBank): ADF36437.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: hCyp2D6 P26
Chemical type: Peptide from protein
Sequence: RFLRLLDLAQEGLKEESGFL
Position: 201-220
Source molecule (GenBank): ADF36437.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: hCyp2D6 P26
Chemical type: Peptide from protein
Sequence: RFLRLLDLAQEGLKEESGFL
Position: 201-220
Source molecule (GenBank): ADF36437.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: hCyp2D6 P42
Chemical type: Peptide from protein
Sequence: RRVQQEIDDVIGQVRRPEMG
Position: 329-348
Source molecule (GenBank): ADF36437.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: hCyp2D6 P42
Chemical type: Peptide from protein
Sequence: RRVQQEIDDVIGQVRRPEMG
Position: 329-348
Source molecule (GenBank): ADF36437.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: hCyp2D6 P51
Chemical type: Peptide from protein
Sequence: SVLKDEAVWEKPFRFHPEHF
Position: 401-420
Source molecule (GenBank): ADF36437.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: hCyp2D6 P51
Chemical type: Peptide from protein
Sequence: SVLKDEAVWEKPFRFHPEHF
Position: 401-420
Source molecule (GenBank): ADF36437.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: hCyp2D6 P52
Chemical type: Peptide from protein
Sequence: WEKPFRFHPEHFLDAQGHFV
Position: 409-428
Source molecule (GenBank): ADF36437.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: hCyp2D6 P52
Chemical type: Peptide from protein
Sequence: WEKPFRFHPEHFLDAQGHFV
Position: 409-428
Source molecule (GenBank): ADF36437.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: hCyp2D6 P7
Chemical type: Peptide from protein
Sequence: VDFQNTPYCFDQLRRRFGDV
Position: 49-68
Source molecule (GenBank): ADF36437.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: liver
Culture conditions: Direct Ex Vivo

Epitope: hCyp2D6 P7
Chemical type: Peptide from protein
Sequence: VDFQNTPYCFDQLRRRFGDV
Position: 49-68
Source molecule (GenBank): ADF36437.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: liver
Culture conditions: Direct Ex Vivo