Reference: Catherine J Reynolds; Corinna Pade; Joseph M Gibbons; Ashley D Otter; Kai-Min Lin; Diana Muñoz Sandoval; Franziska P Pieper; David K Butler; Siyi Liu; George Joy; Nasim Forooghi; Thomas A Treibel; Charlotte Manisty; James C Moon; Amanda Semper; Tim Brooks; Áine McKnight; Daniel M Altmann; Rosemary J Boyton; Hakam Abbass; Aderonke Abiodun; Mashael Alfarih; Zoe Alldis; Daniel M Altmann; Oliver E Amin; Mervyn Andiapen; Jessica Artico; João B Augusto; Georgina L Baca; Sasha N L Bailey; Anish N Bhuva; Alex Boulter; Ruth Bowles; Rosemary J Boyton; Olivia V Bracken; Ben O'Brien; Tim Brooks; Natalie Bullock; David K Butler; Gabriella Captur; Olivia Carr; Nicola Champion; Carmen Chan; Aneesh Chandran; Tom Coleman; Jorge Couto de Sousa; Xose Couto-Parada; Eleanor Cross; Teresa Cutino-Moguel; Silvia D'Arcangelo; Rhodri H Davies; Brooke Douglas; Cecilia Di Genova; Keenan Dieobi-Anene; Mariana O Diniz; Anaya Ellis; Karen Feehan; Malcolm Finlay; Marianna Fontana; Nasim Forooghi; Sasha Francis; Joseph M Gibbons; David Gillespie; Derek Gilroy; Matt Hamblin; Gabrielle Harker; Georgia Hemingway; Jacqueline Hewson; Wendy Heywood; Lauren M Hickling; Bethany Hicks; Aroon D Hingorani; Lee Howes; Ivie Itua; Victor Jardim; Wing-Yiu Jason Lee; Melaniepetra Jensen; Jessica Jones; Meleri Jones; George Joy; Vikas Kapil; Caoimhe Kelly; Hibba Kurdi; Jonathan Lambourne; Kai-Min Lin; Siyi Liu; Aaron Lloyd; Sarah Louth; Mala K Maini; Vineela Mandadapu; Charlotte Manisty; Áine McKnight; Katia Menacho; Celina Mfuko; Kevin Mills; Sebastian Millward; Oliver Mitchelmore; Christopher Moon; James Moon; Diana Muñoz Sandoval; Sam M Murray; Mahdad Noursadeghi; Ashley Otter; Corinna Pade; Susana Palma; Ruth Parker; Kush Patel; Mihaela Pawarova; Steffen E Petersen; Brian Piniera; Franziska P Pieper; Lisa Rannigan; Alicja Rapala; Catherine J Reynolds; Amy Richards; Matthew Robathan; Joshua Rosenheim; Cathy Rowe; Matthew Royds; Jane Sackville West; Genine Sambile; Nathalie M Schmidt; Hannah Selman; Amanda Semper; Andreas Seraphim; Mihaela Simion; Angelique Smit; Michelle Sugimoto; Leo Swadling; Stephen Taylor; Nigel Temperton; Stephen Thomas; George D Thornton; Thomas A Treibel; Art Tucker; Ann Varghese; Jessry Veerapen; Mohit Vijayakumar; Tim Warner; Sophie Welch; Hannah White; Theresa Wodehouse; Lucinda Wynne; Dan Zahedi; Benjamin Chain; James C Moon. "Immune boosting by B.1.1.529 Omicron) depends on previous SARS-CoV-2 exposure." Science (New York, N.Y.) (2022).

Epitope: Wuhan G142D/del143-5
Chemical type: Peptide from protein
Sequence: EFQFCNDPFLGVYYHKNNKSW
Position: 132-152
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Wuhan G142D/del143-5
Chemical type: Peptide from protein
Sequence: EFQFCNDPFLGVYYHKNNKSW
Position: 132-152
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Wuhan G142D/del143-5
Chemical type: Peptide from protein
Sequence: EFQFCNDPFLGVYYHKNNKSW
Position: 132-152
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N440K/G446S
Chemical type: Peptide from protein
Sequence: CVIAWNSNNLDSKVGGNYNY
Position: 432-451
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N440K/G446S
Chemical type: Peptide from protein
Sequence: CVIAWNSNNLDSKVGGNYNY
Position: 432-451
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N440K/G446S
Chemical type: Peptide from protein
Sequence: CVIAWNSNNLDSKVGGNYNY
Position: 432-451
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Wuhan D796Y
Chemical type: Peptide from protein
Sequence: KQIYKTPPIKDFGGFNFSQI
Position: 786-805
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Wuhan D796Y
Chemical type: Peptide from protein
Sequence: KQIYKTPPIKDFGGFNFSQI
Position: 786-805
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Wuhan D796Y
Chemical type: Peptide from protein
Sequence: KQIYKTPPIKDFGGFNFSQI
Position: 786-805
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N969K/L981F
Chemical type: Peptide from protein
Sequence: KQLSSNFGAISSVLNDILSR
Position: 964-983
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N969K/L981F
Chemical type: Peptide from protein
Sequence: KQLSSNFGAISSVLNDILSR
Position: 964-983
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: Wuhan N969K/L981F
Chemical type: Peptide from protein
Sequence: KQLSSNFGAISSVLNDILSR
Position: 964-983
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B.1.1.529 S371L/S373P/S375F
Chemical type: Peptide from protein
Sequence: VADYSVLYNLAPFFTFKCYGV
Position: 359-379
Source molecule (GenBank): UJK14488.1
Assay category: TCell
Result: Negative
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B.1.1.529 S371L/S373P/S375F
Chemical type: Peptide from protein
Sequence: VADYSVLYNLAPFFTFKCYGV
Position: 359-379
Source molecule (GenBank): UJK14488.1
Assay category: TCell
Result: Negative
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B.1.1.529 S371L/S373P/S375F
Chemical type: Peptide from protein
Sequence: VADYSVLYNLAPFFTFKCYGV
Position: 359-379
Source molecule (GenBank): UJK14488.1
Assay category: TCell
Result: Negative
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B.1.1.529 N440K/G446S
Chemical type: Peptide from protein
Sequence: CVIAWNSNKLDSKVSGNYNY
Position: 429-448
Source molecule (GenBank): UJK14488.1
Assay category: TCell
Result: Negative
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B.1.1.529 N440K/G446S
Chemical type: Peptide from protein
Sequence: CVIAWNSNKLDSKVSGNYNY
Position: 429-448
Source molecule (GenBank): UJK14488.1
Assay category: TCell
Result: Negative
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: B.1.1.529 N440K/G446S
Chemical type: Peptide from protein
Sequence: CVIAWNSNKLDSKVSGNYNY
Position: 429-448
Source molecule (GenBank): UJK14488.1
Assay category: TCell
Result: Negative
Host:  7-8 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo