Reference: Arvind Sharma; Xiaokang Zhang; Wanwisa Dejnirattisai; Xinghong Dai; Danyang Gong; Wiyada Wongwiwat; Stéphane Duquerroy; Alexander Rouvinski; Marie-Christine Vaney; Pablo Guardado-Calvo; Ahmed Haouz; Patrick England; Ren Sun; Z Hong Zhou; Juthathip Mongkolsapaya; Gavin R Screaton; Felix A Rey. "The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses." Cell (2021).

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive
Quantitative measurement: 20.7

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive
Quantitative measurement: 18.4

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.42

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive
Quantitative measurement: 16.2

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive
Quantitative measurement: 25.3

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.03

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.58

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.6

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.7

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.41

Epitope: Epitope of scFv C10 on DENV4 sE
Chemical type: Region on multi-chain protein
Discontinuous residues: A: N142, T144, T145, A146, T147, C149, V172, R174, W176, G177, N178, G179, C180, G181, R322, D324; B: R77, H102, G103, E119, T121, K278, D346, M353, D384, K385, K398, N437
Source molecule (GenBank): AAN38665.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.42

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.41

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.58

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.03

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.6

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.1

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.0

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive
Quantitative measurement: 25.3

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive
Quantitative measurement: 18.4

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive
Quantitative measurement: 20.7

Epitope: Epitope of Fab C10 on ZIKV sE
Chemical type: Discontinuous protein residues
Discontinuous residues: R292, E334, V336, H438, G440, M441, I442, R454, R573, K606, E660, N661, K663
Source molecule (GenBank): AVG19275.1
Assay category: BCell
Result: Positive
Quantitative measurement: 16.2