Reference: Rebekka Duhen; Olivier Fesneau; Kimberly A Samson; Alexandra K Frye; Michael Beymer; Venkatesh Rajamanickam; David Ross; Eric Tran; Brady Bernard; Andrew D Weinberg; Thomas Duhen. "PD-1 and ICOS coexpression identifies tumor-reactive CD4+ T cells in human solid tumors." The Journal of clinical investigation (2022).

Epitope: HPV16-E6-6
Chemical type: Peptide from protein
Sequence: QLCTELQTTIHDIIL
Position: 21-35
Source molecule (GenBank): P03126
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: HPV16-E6-6
Chemical type: Peptide from protein
Sequence: QLCTELQTTIHDIIL
Position: 21-35
Source molecule (GenBank): P03126
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: HPV16-E6-7
Chemical type: Peptide from protein
Sequence: ELQTTIHDIILECVY
Position: 25-39
Source molecule (GenBank): P03126
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: HPV16-E6-7
Chemical type: Peptide from protein
Sequence: ELQTTIHDIILECVY
Position: 25-39
Source molecule (GenBank): P03126
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: HPV16-E6-27
Chemical type: Peptide from protein
Sequence: DLLIRCINCQKPLCP
Position: 105-119
Source molecule (GenBank): P03126
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: HPV16-E6-27
Chemical type: Peptide from protein
Sequence: DLLIRCINCQKPLCP
Position: 105-119
Source molecule (GenBank): P03126
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: HPV16-E6-29
Chemical type: Peptide from protein
Sequence: CQKPLCPEEKQRHLD
Position: 113-127
Source molecule (GenBank): P03126
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: HPV16-E6-29
Chemical type: Peptide from protein
Sequence: CQKPLCPEEKQRHLD
Position: 113-127
Source molecule (GenBank): P03126
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: HPV16-E6-30
Chemical type: Peptide from protein
Sequence: LCPEEKQRHLDKKQR
Position: 117-131
Source molecule (GenBank): P03126
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: HPV16-E6-30
Chemical type: Peptide from protein
Sequence: LCPEEKQRHLDKKQR
Position: 117-131
Source molecule (GenBank): P03126
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: HPV16-E6-37
Chemical type: Peptide from protein
Sequence: SCCRSSRTRRETQL
Position: 145-158
Source molecule (GenBank): P03126
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: HPV16-E6-37
Chemical type: Peptide from protein
Sequence: SCCRSSRTRRETQL
Position: 145-158
Source molecule (GenBank): P03126
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: ZNF579
Chemical type: Peptide, no natural source
Sequence: VHGPLSLLAPLPVAGKKDDKASGAR
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: ZNF579
Chemical type: Peptide, no natural source
Sequence: VHGPLSLLAPLPVAGKKDDKASGAR
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: MVK
Chemical type: Peptide, no natural source
Sequence: LQILLTNTKVPRSTRALVAGVRNRL
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: MVK
Chemical type: Peptide, no natural source
Sequence: LQILLTNTKVPRSTRALVAGVRNRL
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: RANBP2
Chemical type: Peptide, no natural source
Sequence: GNQEKKSEKPLESGTGFQAQDISGQ
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: RAI1
Chemical type: Peptide, no natural source
Sequence: MMCSSCQEAGATVGCCHKGCLHTYH
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: ANLN
Chemical type: Peptide, no natural source
Sequence: LSGGEEKSCTKPWPSKKRCSDNTEV
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: EPS15L1
Chemical type: Peptide, no natural source
Sequence: MAAPLILLSQQIPTGNSLY
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: FADS6
Chemical type: Peptide, no natural source
Sequence: DVVRTSSWWERHSVDCAILALSLFA
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: TRAM1_WT
Chemical type: Peptide from protein
Sequence: EDIPRQLVYIGLYLFHIAGAYLLNL
Position: 191-215
Source molecule (GenBank): Q15629.3
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: skin
Culture conditions: Direct Ex Vivo

Epitope: UBASH3B
Chemical type: Peptide, no natural source
Sequence: DALGEALQTTVSHWKCKFSAPLPLE
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: skin
Culture conditions: Direct Ex Vivo