Reference: Erik Depla; Annegret Van der Aa; Brian D Livingston; Claire Crimi; Koen Allosery; Veronique De Brabandere; Jonathan Krakover; Sidharta Murthy; Manley Huang; Scott Power; Lilia Babé; Carol Dahlberg; Denise McKinney; Alessandro Sette; Scott Southwood; Ramilla Philip; Mark J Newman; Lydie Meheus. "Rational design of a multiepitope vaccine encoding T-lymphocyte epitopes for treatment of chronic hepatitis B virus infections." Journal of virology (2008).

Epitope: pol 429
Chemical type: Peptide from protein
Sequence: HPAAMPHLL
Position: 399-407
Source molecule (GenBank): CAL29860.1
Assay category: TCell
Result: Negative
Host:  8-14 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: pol 429
Chemical type: Peptide from protein
Sequence: HPAAMPHLL
Position: 399-407
Source molecule (GenBank): CAL29860.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 56.6

Epitope: pol 429
Chemical type: Peptide from protein
Sequence: HPAAMPHLL
Position: 399-407
Source molecule (GenBank): CAL29860.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 297.7

Epitope: pol 429
Chemical type: Peptide from protein
Sequence: HPAAMPHLL
Position: 399-407
Source molecule (GenBank): CAL29860.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 543.5

Epitope: pol 429
Chemical type: Peptide from protein
Sequence: HPAAMPHLL
Position: 399-407
Source molecule (GenBank): CAL29860.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 160.4

Epitope: pol 429
Chemical type: Peptide from protein
Sequence: HPAAMPHLL
Position: 399-407
Source molecule (GenBank): CAL29860.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 923.3

Epitope: core 419
Chemical type: Peptide from protein
Sequence: DLLDTASALY
Position: 29-38
Source molecule (GenBank): AAP79751.1
Assay category: TCell
Result: Positive
Host:  8-14 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: core 419
Chemical type: Peptide from protein
Sequence: DLLDTASALY
Position: 29-38
Source molecule (GenBank): AAP79751.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.3

Epitope: core 419
Chemical type: Peptide from protein
Sequence: DLLDTASALY
Position: 29-38
Source molecule (GenBank): AAP79751.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 74.1

Epitope: core 419
Chemical type: Peptide from protein
Sequence: DLLDTASALY
Position: 29-38
Source molecule (GenBank): AAP79751.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 37.0

Epitope: core 137
Chemical type: Peptide from protein
Sequence: LTFGRETVLEY
Position: 108-118
Source molecule (GenBank): BAF42671.1
Assay category: TCell
Result: Negative
Host:  8-14 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: core 137
Chemical type: Peptide from protein
Sequence: LTFGRETVLEY
Position: 108-118
Source molecule (GenBank): BAF42671.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 16.8

Epitope: core 137
Chemical type: Peptide from protein
Sequence: LTFGRETVLEY
Position: 108-118
Source molecule (GenBank): BAF42671.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 27.8

Epitope: core 137
Chemical type: Peptide from protein
Sequence: LTFGRETVLEY
Position: 108-118
Source molecule (GenBank): BAF42671.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 430.8

Epitope: pol 392
Chemical type: Peptide from protein
Sequence: SWPKFAVPNL
Position: 392-401
Source molecule (GenBank): AAP79852.1
Assay category: TCell
Result: Negative
Host:  8-14 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: pol 392
Chemical type: Peptide from protein
Sequence: SWPKFAVPNL
Position: 392-401
Source molecule (GenBank): AAP79852.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 1.0

Epitope: pol 392
Chemical type: Peptide from protein
Sequence: SWPKFAVPNL
Position: 392-401
Source molecule (GenBank): AAP79852.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.4

Epitope: pol 412
Chemical type: Peptide from protein
Sequence: LQSLTNLLSSNLSWL
Position: 412-426
Source molecule (GenBank): AAD16253.1
Assay category: TCell
Result: Negative
Host:  8-14 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: pol 412
Chemical type: Peptide from protein
Sequence: LQSLTNLLSSNLSWL
Position: 412-426
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 2.0

Epitope: pol 412
Chemical type: Peptide from protein
Sequence: LQSLTNLLSSNLSWL
Position: 412-426
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 21.0

Epitope: pol 412
Chemical type: Peptide from protein
Sequence: LQSLTNLLSSNLSWL
Position: 412-426
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 10.0

Epitope: pol 412
Chemical type: Peptide from protein
Sequence: LQSLTNLLSSNLSWL
Position: 412-426
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 47.0

Epitope: pol 412
Chemical type: Peptide from protein
Sequence: LQSLTNLLSSNLSWL
Position: 412-426
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 303.0

Epitope: pol 412
Chemical type: Peptide from protein
Sequence: LQSLTNLLSSNLSWL
Position: 412-426
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 397.0

Epitope: pol 412
Chemical type: Peptide from protein
Sequence: LQSLTNLLSSNLSWL
Position: 412-426
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 143.0

Epitope: pol 412
Chemical type: Peptide from protein
Sequence: LQSLTNLLSSNLSWL
Position: 412-426
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 173.0

Epitope: pol 412
Chemical type: Peptide from protein
Sequence: LQSLTNLLSSNLSWL
Position: 412-426
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 598.0

Epitope: pol 412
Chemical type: Peptide from protein
Sequence: LQSLTNLLSSNLSWL
Position: 412-426
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 791.0

Epitope: pol 412
Chemical type: Peptide from protein
Sequence: LQSLTNLLSSNLSWL
Position: 412-426
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1067.0

Epitope: pol 412
Chemical type: Peptide from protein
Sequence: LQSLTNLLSSNLSWL
Position: 412-426
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1837.0

Epitope: pol 412
Chemical type: Peptide from protein
Sequence: LQSLTNLLSSNLSWL
Position: 412-426
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 4179.0

Epitope: pol 694
Chemical type: Peptide from protein
Sequence: LCQVFADATPTGWGL
Position: 694-708
Source molecule (GenBank): AAD16253.1
Assay category: TCell
Result: Positive
Host:  8-14 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: pol 694
Chemical type: Peptide from protein
Sequence: LCQVFADATPTGWGL
Position: 694-708
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 7470.0

Epitope: pol 694
Chemical type: Peptide from protein
Sequence: LCQVFADATPTGWGL
Position: 694-708
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 5009.0

Epitope: pol 694
Chemical type: Peptide from protein
Sequence: LCQVFADATPTGWGL
Position: 694-708
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 490.0

Epitope: pol 694
Chemical type: Peptide from protein
Sequence: LCQVFADATPTGWGL
Position: 694-708
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1203.0

Epitope: pol 694
Chemical type: Peptide from protein
Sequence: LCQVFADATPTGWGL
Position: 694-708
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 67.0

Epitope: pol 694
Chemical type: Peptide from protein
Sequence: LCQVFADATPTGWGL
Position: 694-708
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 2022.0

Epitope: pol 694
Chemical type: Peptide from protein
Sequence: LCQVFADATPTGWGL
Position: 694-708
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1808.0

Epitope: pol 694
Chemical type: Peptide from protein
Sequence: LCQVFADATPTGWGL
Position: 694-708
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1044.0

Epitope: pol 385
Chemical type: Peptide from protein
Sequence: ESRLVVDFSQFSRGN
Position: 385-399
Source molecule (GenBank): AAD16253.1
Assay category: TCell
Result: Positive
Host:  8-14 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: pol 385
Chemical type: Peptide from protein
Sequence: ESRLVVDFSQFSRGN
Position: 385-399
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 7372.0

Epitope: pol 385
Chemical type: Peptide from protein
Sequence: ESRLVVDFSQFSRGN
Position: 385-399
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1368.0

Epitope: pol 385
Chemical type: Peptide from protein
Sequence: ESRLVVDFSQFSRGN
Position: 385-399
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 208.0

Epitope: pol 385
Chemical type: Peptide from protein
Sequence: ESRLVVDFSQFSRGN
Position: 385-399
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 251.0

Epitope: pol 385
Chemical type: Peptide from protein
Sequence: ESRLVVDFSQFSRGN
Position: 385-399
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 36.0

Epitope: pol 385
Chemical type: Peptide from protein
Sequence: ESRLVVDFSQFSRGN
Position: 385-399
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 946.0

Epitope: pol 385
Chemical type: Peptide from protein
Sequence: ESRLVVDFSQFSRGN
Position: 385-399
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 2525.0

Epitope: pol 385
Chemical type: Peptide from protein
Sequence: ESRLVVDFSQFSRGN
Position: 385-399
Source molecule (GenBank): AAD16253.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 8711.0