Reference: Jeff Alexander; Pamuk Bilsel; Marie-France del Guercio; Stephani Stewart; Aleksandra Marinkovic-Petrovic; Scott Southwood; Claire Crimi; Lo Vang; Les Walker; Glenn Ishioka; Vivek Chitnis; Alessandro Sette; Erika Assarsson; Drew Hannaman; Jason Botten; Mark J Newman. "Universal influenza DNA vaccine encoding conserved CD4+ T cell epitopes protects against lethal viral challenge in HLA-DR transgenic mice." Vaccine (2010).

Epitope: PB1.318
Chemical type: Peptide from protein
Sequence: FLAMITYITRNQPEW
Position: 318-332
Source molecule (GenBank): AAC32096.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: PB1.318
Chemical type: Peptide from protein
Sequence: FLAMITYITRNQPEW
Position: 318-332
Source molecule (GenBank): AAC32096.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 8.0

Epitope: PB1.318
Chemical type: Peptide from protein
Sequence: FLAMITYITRNQPEW
Position: 318-332
Source molecule (GenBank): AAC32096.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 59.0

Epitope: PB1.318
Chemical type: Peptide from protein
Sequence: FLAMITYITRNQPEW
Position: 318-332
Source molecule (GenBank): AAC32096.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 60.0

Epitope: PB1.318
Chemical type: Peptide from protein
Sequence: FLAMITYITRNQPEW
Position: 318-332
Source molecule (GenBank): AAC32096.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 64.0

Epitope: PB1.318
Chemical type: Peptide from protein
Sequence: FLAMITYITRNQPEW
Position: 318-332
Source molecule (GenBank): AAC32096.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 65.0

Epitope: PB1.318
Chemical type: Peptide from protein
Sequence: FLAMITYITRNQPEW
Position: 318-332
Source molecule (GenBank): AAC32096.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 74.0

Epitope: PB1.318
Chemical type: Peptide from protein
Sequence: FLAMITYITRNQPEW
Position: 318-332
Source molecule (GenBank): AAC32096.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 126.0

Epitope: PB1.318
Chemical type: Peptide from protein
Sequence: FLAMITYITRNQPEW
Position: 318-332
Source molecule (GenBank): AAC32096.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 174.0

Epitope: PB1.318
Chemical type: Peptide from protein
Sequence: FLAMITYITRNQPEW
Position: 318-332
Source molecule (GenBank): AAC32096.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 200.0

Epitope: PB1.318
Chemical type: Peptide from protein
Sequence: FLAMITYITRNQPEW
Position: 318-332
Source molecule (GenBank): AAC32096.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 590.0

Epitope: PB1.318
Chemical type: Peptide from protein
Sequence: FLAMITYITRNQPEW
Position: 318-332
Source molecule (GenBank): AAC32096.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 769.0

Epitope: PB1.318
Chemical type: Peptide from protein
Sequence: FLAMITYITRNQPEW
Position: 318-332
Source molecule (GenBank): AAC32096.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1140.0

Epitope: PB1.318
Chemical type: Peptide from protein
Sequence: FLAMITYITRNQPEW
Position: 318-332
Source molecule (GenBank): AAC32096.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 10000.0

Epitope: PB2.312
Chemical type: Peptide from protein
Sequence: KAAMGLRISSSFSFG
Position: 312-326
Source molecule (GenBank): ACF54487.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PB2.312
Chemical type: Peptide from protein
Sequence: KAAMGLRISSSFSFG
Position: 312-326
Source molecule (GenBank): ACF54487.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 1.0

Epitope: PB2.312
Chemical type: Peptide from protein
Sequence: KAAMGLRISSSFSFG
Position: 312-326
Source molecule (GenBank): ACF54487.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 3.0

Epitope: PB2.312
Chemical type: Peptide from protein
Sequence: KAAMGLRISSSFSFG
Position: 312-326
Source molecule (GenBank): ACF54487.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 4.0

Epitope: PB2.312
Chemical type: Peptide from protein
Sequence: KAAMGLRISSSFSFG
Position: 312-326
Source molecule (GenBank): ACF54487.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 4.0

Epitope: PB2.312
Chemical type: Peptide from protein
Sequence: KAAMGLRISSSFSFG
Position: 312-326
Source molecule (GenBank): ACF54487.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 37.0

Epitope: PB2.312
Chemical type: Peptide from protein
Sequence: KAAMGLRISSSFSFG
Position: 312-326
Source molecule (GenBank): ACF54487.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 45.0

Epitope: PB2.312
Chemical type: Peptide from protein
Sequence: KAAMGLRISSSFSFG
Position: 312-326
Source molecule (GenBank): ACF54487.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 47.0

Epitope: PB2.312
Chemical type: Peptide from protein
Sequence: KAAMGLRISSSFSFG
Position: 312-326
Source molecule (GenBank): ACF54487.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 58.0

Epitope: PB2.312
Chemical type: Peptide from protein
Sequence: KAAMGLRISSSFSFG
Position: 312-326
Source molecule (GenBank): ACF54487.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 79.0

Epitope: PB2.312
Chemical type: Peptide from protein
Sequence: KAAMGLRISSSFSFG
Position: 312-326
Source molecule (GenBank): ACF54487.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 398.0

Epitope: PB2.312
Chemical type: Peptide from protein
Sequence: KAAMGLRISSSFSFG
Position: 312-326
Source molecule (GenBank): ACF54487.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 452.0

Epitope: PB2.312
Chemical type: Peptide from protein
Sequence: KAAMGLRISSSFSFG
Position: 312-326
Source molecule (GenBank): ACF54487.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 466.0

Epitope: PB2.312
Chemical type: Peptide from protein
Sequence: KAAMGLRISSSFSFG
Position: 312-326
Source molecule (GenBank): ACF54487.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 501.0

Epitope: M1.135
Chemical type: Peptide from protein
Sequence: MGTVTTEVALGLVCA
Position: 135-149
Source molecule (GenBank): Q77Y95.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: M1.135
Chemical type: Peptide from protein
Sequence: MGTVTTEVALGLVCA
Position: 135-149
Source molecule (GenBank): Q77Y95.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 769.0

Epitope: M1.135
Chemical type: Peptide from protein
Sequence: MGTVTTEVALGLVCA
Position: 135-149
Source molecule (GenBank): Q77Y95.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 924.0

Epitope: M1.135
Chemical type: Peptide from protein
Sequence: MGTVTTEVALGLVCA
Position: 135-149
Source molecule (GenBank): Q77Y95.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 1589.0

Epitope: M1.135
Chemical type: Peptide from protein
Sequence: MGTVTTEVALGLVCA
Position: 135-149
Source molecule (GenBank): Q77Y95.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 4234.0

Epitope: M1.135
Chemical type: Peptide from protein
Sequence: MGTVTTEVALGLVCA
Position: 135-149
Source molecule (GenBank): Q77Y95.1
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 7609.0

Epitope: M1.135
Chemical type: Peptide from protein
Sequence: MGTVTTEVALGLVCA
Position: 135-149
Source molecule (GenBank): Q77Y95.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 10000.0

Epitope: M1.135
Chemical type: Peptide from protein
Sequence: MGTVTTEVALGLVCA
Position: 135-149
Source molecule (GenBank): Q77Y95.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 10000.0

Epitope: M1.135
Chemical type: Peptide from protein
Sequence: MGTVTTEVALGLVCA
Position: 135-149
Source molecule (GenBank): Q77Y95.1
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 10000.0

Epitope: M1.135
Chemical type: Peptide from protein
Sequence: MGTVTTEVALGLVCA
Position: 135-149
Source molecule (GenBank): Q77Y95.1
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 58.0

Epitope: M1.135
Chemical type: Peptide from protein
Sequence: MGTVTTEVALGLVCA
Position: 135-149
Source molecule (GenBank): Q77Y95.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 142.0

Epitope: M1.135
Chemical type: Peptide from protein
Sequence: MGTVTTEVALGLVCA
Position: 135-149
Source molecule (GenBank): Q77Y95.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 321.0

Epitope: M1.135
Chemical type: Peptide from protein
Sequence: MGTVTTEVALGLVCA
Position: 135-149
Source molecule (GenBank): Q77Y95.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 348.0

Epitope: M1.135
Chemical type: Peptide from protein
Sequence: MGTVTTEVALGLVCA
Position: 135-149
Source molecule (GenBank): Q77Y95.1
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 355.0