Reference: Malte Mohme; Christian Hotz; Stefan Stevanovic; Thomas Binder; Jar-How Lee; Michal Okoniewski; Thomas Eiermann; Mireia Sospedra; Hans-Georg Rammensee; Roland Martin. "HLA-DR15-derived self-peptides are involved in increased autologous T cell proliferation in multiple sclerosis." Brain : a journal of neurology (2013).

Epitope: P13
Chemical type: Peptide from protein
Sequence: TQSYSLQLSNLKMED
Position: 40-54
Source molecule (GenBank): NP_001171644.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P33
Chemical type: Peptide from protein
Sequence: YDMNAANVGWNNSTFA
Position: 91-106
Source molecule (GenBank): AAA36179.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P36
Chemical type: Peptide from protein
Sequence: SYLDPPDLPSNSNDDLLSL
Position: 946-964
Source molecule (GenBank): AAQ15173.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P38
Chemical type: Peptide from protein
Sequence: VDIFQVVKALRKA
Position: 1003-1015
Source molecule (GenBank): AAD15273.2
Assay category: MhcLigandElution
Result: Positive

Epitope: P43
Chemical type: Peptide from protein
Sequence: PAEDWAGLDEDEDAHVWEDN
Position: 23-42
Source molecule (GenBank): EAW76747.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P45
Chemical type: Peptide from protein
Sequence: MIDVTKSYYQKFLPLTQV
Position: 123-140
Source molecule (GenBank): EAW55808.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P47
Chemical type: Peptide from protein
Sequence: LMQALPMGALPQ
Position: 98-109
Source molecule (GenBank): AAA36304.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P56
Chemical type: Peptide from protein
Sequence: ATPLLMQALPMGALPQ
Position: 94-109
Source molecule (GenBank): AAA36304.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P60
Chemical type: Peptide from protein
Sequence: MATPLLMQALPMGALP
Position: 93-108
Source molecule (GenBank): AAA36304.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P69
Chemical type: Peptide from protein
Sequence: ATPLLMQALPMGALPQGP
Position: 94-111
Source molecule (GenBank): AAA36304.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P75
Chemical type: Peptide from protein
Sequence: IGLAKDDQLKVHGF
Position: 100-113
Source molecule (GenBank): AAD19900.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P80
Chemical type: Peptide from protein
Sequence: FGSAFATPFLVVRHQLLKT
Position: 45-63
Source molecule (GenBank): NP_001858.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P83
Chemical type: Peptide from protein
Sequence: YFGSAFATPFLVVRHQLLKT
Position: 44-63
Source molecule (GenBank): NP_001858.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P90
Chemical type: Peptide from protein
Sequence: FSNKITPIQSKEAY
Position: 210-223
Source molecule (GenBank): AAH40224.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P91
Chemical type: Peptide from protein
Sequence: PSLSHNLLVD
Position: 466-475
Source molecule (GenBank): Q9ULA0.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P93
Chemical type: Peptide from protein
Sequence: VGAHAGEYGAEALERM
Position: 18-33
Source molecule (GenBank): AAK15770.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P111
Chemical type: Peptide from protein
Sequence: MRYVASYLLAALGGN
Position: 1-15
Source molecule (GenBank): NP_000995.1
Assay category: MhcLigandElution
Result: Positive

Epitope: P116
Chemical type: Peptide from protein
Sequence: FYGQTLGQAQAHSQEQ
Position: 585-600
Source molecule (GenBank): AAC50893.1
Assay category: MhcLigandElution
Result: Positive

Epitope: Peptide 19
Chemical type: Peptide from protein
Sequence: DWTFQTLVMLETVPR
Position: 145-159
Source molecule (GenBank): AAA59780.1
Assay category: TCell
Result: Positive
Host:  30-49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 120
Chemical type: Peptide from protein
Sequence: MLSGVGGFVLGLIFL
Position: 231-245
Source molecule (GenBank): P03992.2
Assay category: TCell
Result: Positive
Host:  30-49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 122
Chemical type: Peptide from protein
Sequence: IRQRSQKGLLH
Position: 251-261
Source molecule (GenBank): P03992.2
Assay category: TCell
Result: Negative
Host:  30-49 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 6
Chemical type: Peptide from protein
Sequence: ERVRFLDRYFYNQEE
Position: 51-65
Source molecule (GenBank): NP_002115.2
Assay category: TCell
Result: Positive
Host:  30-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 32
Chemical type: Peptide from protein
Sequence: ERVRFLHRDIYNQEE
Position: 51-65
Source molecule (GenBank): NP_002116.2
Assay category: TCell
Result: Positive
Host:  30-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Peptide 22
Chemical type: Peptide from protein
Sequence: SPLTVEWRARSESAQ
Position: 211-225
Source molecule (GenBank): NP_002115.2
Assay category: TCell
Result: Positive
Host:  30-49 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo