Reference: Wei-Ching Liang; Hongkang Xi; Dawei Sun; Luigi D'Ascenzo; Jonathan Zarzar; Nicole Stephens; Ryan Cook; Yinyin Li; Zhengmao Ye; Marissa Matsumoto; Jian Payandeh; Matthieu Masureel; Yan Wu. "Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability." mAbs (2024).

Epitope: Epitope of Fab h1340.SA.LV on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: P31, W32, N66, Y68, T76, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive

Epitope: Epitope of Fab h1340.SA.LV on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: P31, W32, N66, Y68, T76, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 1.51

Epitope: Epitope of Fab h1340.SA.LV on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: P31, W32, N66, Y68, T76, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00419

Epitope: Epitope of Fab h1340.SA.LV on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: P31, W32, N66, Y68, T76, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 279000.0

Epitope: Epitope of Fab h1340.SA.LV on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: P31, W32, N66, Y68, T76, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 444000.0

Epitope: Epitope of Fab h1340.SA.LV on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: P31, W32, N66, Y68, T76, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 346000.0

Epitope: Epitope of Fab h1340.SA.LV on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: P31, W32, N66, Y68, T76, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 3.82

Epitope: Epitope of Fab h1340.SA.LV on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: P31, W32, N66, Y68, T76, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0017

Epitope: Epitope of Fab h1340.SA.LV on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: P31, W32, N66, Y68, T76, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.8

Epitope: Epitope of Fab h1340.SA.LV on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: P31, W32, N66, Y68, T76, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000276

Epitope: Epitope of Fab h1340.SA.LV on hPD-1
Chemical type: Discontinuous protein residues
Discontinuous residues: P31, W32, N66, Y68, T76, I126, S127, L128, P130, K131, A132, Q133, I134, K135, E136
Source molecule (GenBank): Q15116.3
Assay category: BCell
Result: Positive
Quantitative measurement: 2.51