Reference: Valerie Oberhardt; Hendrik Luxenburger; Janine Kemming; Isabel Schulien; Kevin Ciminski; Sebastian Giese; Benedikt Csernalabics; Julia Lang-Meli; Iga Janowska; Julian Staniek; Katharina Wild; Kristi Basho; Mircea Stefan Marinescu; Jonas Fuchs; Fernando Topfstedt; Ales Janda; Oezlem Sogukpinar; Hanna Hilger; Katarina Stete; Florian Emmerich; Bertram Bengsch; Cornelius F Waller; Siegbert Rieg; Sagar; Tobias Boettler; Katharina Zoldan; Georg Kochs; Martin Schwemmle; Marta Rizzi; Robert Thimme; Christoph Neumann-Haefelin; Maike Hofmann. "Rapid and stable mobilization of CD8<sup>+</sup> T cells by SARS-CoV-2 mRNA vaccine." Nature (2021).

Epitope: QPTESIVRF
Chemical type: Peptide from protein
Sequence: QPTESIVRF
Position: 321-329
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: QPTESIVRF
Chemical type: Peptide from protein
Sequence: QPTESIVRF
Position: 321-329
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Positive-Intermediate
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-7
Chemical type: Peptide from protein
Sequence: FRSSVLHSTQDLFLPFFS
Position: 43-60
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-40
Chemical type: Peptide from protein
Sequence: ENGTITDAVDCALDPLSE
Position: 281-298
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-56
Chemical type: Peptide from protein
Sequence: TNVYADSFVIRGDEVRQI
Position: 393-410
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-64
Chemical type: Peptide from protein
Sequence: YNYLYRLFRKSNLKPFER
Position: 449-466
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-70
Chemical type: Peptide from protein
Sequence: PLQSYGFQPTNGVGYQPY
Position: 491-508
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-74
Chemical type: Peptide from protein
Sequence: HAPATVCGPKKSTNLVKN
Position: 519-536
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-101
Chemical type: Peptide from protein
Sequence: SNNSIAIPTNFTISVTTE
Position: 708-725
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-109
Chemical type: Peptide from protein
Sequence: NRALTGIAVEQDKNTQEV
Position: 764-781
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-116
Chemical type: Peptide from protein
Sequence: SKRSFIEDLLFNKVTLAD
Position: 813-830
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-125
Chemical type: Peptide from protein
Sequence: ALLAGTITSGWTFGAGAA
Position: 876-893
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-127
Chemical type: Peptide from protein
Sequence: AGAALQIPFAMQMAYRFN
Position: 890-907
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-132
Chemical type: Peptide from protein
Sequence: NQFNSAIGKIQDSLSSTA
Position: 925-942
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-133
Chemical type: Peptide from protein
Sequence: GKIQDSLSSTASALGKLQ
Position: 932-949
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-135
Chemical type: Peptide from protein
Sequence: GKLQDVVNQNAQALNTLV
Position: 946-963
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-142
Chemical type: Peptide from protein
Sequence: RLITGRLQSLQTYVTQQL
Position: 995-1012
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-161
Chemical type: Peptide from protein
Sequence: VVIGIVNNTVYDPLQPEL
Position: 1128-1145
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-171
Chemical type: Peptide from protein
Sequence: IDLQELGKYEQYIKWPWY
Position: 1198-1215
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: Spike-olp-178
Chemical type: Peptide from protein
Sequence: CCSCGSCCKFDEDDSEPV
Position: 1247-1264
Source molecule (GenBank): QHD43416.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo