Reference: Ruben C Hoogeveen; Suzan Dijkstra; Lea M Bartsch; Hannah K Drescher; Jasneet Aneja; Maxwell P Robidoux; James A Cheney; Joerg Timm; Adam Gehring; Paulo Sergio Fonseca de Sousa; Lya Ximenez; Luis Baiao Peliganga; Anita Pitts; Fiona B Evans; André Boonstra; Arthur Y Kim; Lia L Lewis-Ximenez; Georg M Lauer. "Hepatitis B virus-specific CD4 T cell responses differentiate functional cure from chronic surface antigen<sup>+</sup> infection." Journal of hepatology (2022).

Epitope: HBV-A-2
Chemical type: Peptide from protein
Sequence: LIISCTCPTVQASKLC
Position: 8-23
Source molecule (GenBank): AAY24390.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HBV-A-2
Chemical type: Peptide from protein
Sequence: LIISCTCPTVQASKLC
Position: 8-23
Source molecule (GenBank): AAY24390.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBV-A-28
Chemical type: Peptide from protein
Sequence: SVPNPLGFFPDHQLDPAF
Position: 17-34
Source molecule (GenBank): AAR07092.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBV-A-28
Chemical type: Peptide from protein
Sequence: SVPNPLGFFPDHQLDPAF
Position: 17-34
Source molecule (GenBank): AAR07092.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HBV-A-36
Chemical type: Peptide from protein
Sequence: AQGILTTVSTIPPPASTN
Position: 81-98
Source molecule (GenBank): AAR07092.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBV-AD-58
Chemical type: Peptide from protein
Sequence: FLFILLLCLIFLLVLLDY
Position: 257-274
Source molecule (GenBank): AAR07092.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBV-A-62
Chemical type: Peptide from protein
Sequence: TTSTGPCKTCTTPAQGNS
Position: 289-306
Source molecule (GenBank): AAR07092.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBV-A-68
Chemical type: Peptide from protein
Sequence: WEWASVRFSWLSLLVPFV
Position: 337-354
Source molecule (GenBank): AAR07092.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HBV-A-68
Chemical type: Peptide from protein
Sequence: WEWASVRFSWLSLLVPFV
Position: 337-354
Source molecule (GenBank): AAR07092.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBV-A-68
Chemical type: Peptide from protein
Sequence: WEWASVRFSWLSLLVPFV
Position: 337-354
Source molecule (GenBank): AAR07092.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HBV-A-73
Chemical type: Peptide from protein
Sequence: PSLYSIVSPFIPLLPIFF
Position: 377-394
Source molecule (GenBank): AAR07092.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HBV-A-73
Chemical type: Peptide from protein
Sequence: PSLYSIVSPFIPLLPIFF
Position: 377-394
Source molecule (GenBank): AAR07092.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBV-A-73
Chemical type: Peptide from protein
Sequence: PSLYSIVSPFIPLLPIFF
Position: 377-394
Source molecule (GenBank): AAR07092.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HBV-A-79
Chemical type: Peptide from protein
Sequence: PLGTLSSPSPSAVPADHG
Position: 33-50
Source molecule (GenBank): ACO89746.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBV-A-87
Chemical type: Peptide from protein
Sequence: TLGLPAMSTTDLEAYFKD
Position: 97-114
Source molecule (GenBank): ACO89746.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBV-A-88
Chemical type: Peptide from protein
Sequence: TTDLEAYFKDCVFKDWEE
Position: 105-122
Source molecule (GenBank): ACO89746.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HBV-A-88
Chemical type: Peptide from protein
Sequence: TTDLEAYFKDCVFKDWEE
Position: 105-122
Source molecule (GenBank): ACO89746.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBV-A-88
Chemical type: Peptide from protein
Sequence: TTDLEAYFKDCVFKDWEE
Position: 105-122
Source molecule (GenBank): ACO89746.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HBV-AD-92
Chemical type: Peptide from protein
Sequence: CRHKLVCAPAPCNFFTSA
Position: 137-154
Source molecule (GenBank): ACO89746.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBV-A-116
Chemical type: Peptide from protein
Sequence: WEQELQHGRLVIKTSQRH
Position: 177-194
Source molecule (GenBank): ACF95009.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBV-A-134
Chemical type: Peptide from protein
Sequence: SVFSCWWLQFRNSKPCSE
Position: 321-338
Source molecule (GenBank): ACF95009.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBV-A-136
Chemical type: Peptide from protein
Sequence: SEYCLSHLVNLREDWGPC
Position: 337-354
Source molecule (GenBank): ACF95009.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBV-A-152
Chemical type: Peptide from protein
Sequence: SNSRINNNQYGTMQNLHD
Position: 465-482
Source molecule (GenBank): ACF95009.1
Assay category: TCell
Result: Negative
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBV-A-184
Chemical type: Peptide from protein
Sequence: FVAPLPIHTAELLAACFA
Position: 721-738
Source molecule (GenBank): ACF95009.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HBV-A-184
Chemical type: Peptide from protein
Sequence: FVAPLPIHTAELLAACFA
Position: 721-738
Source molecule (GenBank): ACF95009.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: HBV-AD-192
Chemical type: Peptide from protein
Sequence: ALNPADDPSRGRLGLSRP
Position: 785-802
Source molecule (GenBank): ACF95009.1
Assay category: TCell
Result: Positive
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo