Reference: Amrita Basu; Gabriella K Albert; Sabrina Awshah; Jashodeep Datta; Krithika N Kodumudi; Corey Gallen; Amber Beyer; Keiran S M Smalley; Paulo C Rodriguez; Derek R Duckett; Peter A Forsyth; Aixa Soyano; Gary K Koski; Ricardo Lima Barros Costa; Heather Han; Hatem Soliman; Marie Catherine Lee; Pawel Kalinski; Brian J Czerniecki. "Identification of Immunogenic MHC Class II Human HER3 Peptides that Mediate Anti-HER3 CD4<sup>+</sup> Th1 Responses and Potential Use as a Cancer Vaccine." Cancer immunology research (2022).

Epitope: ECD p8
Chemical type: Peptide from protein
Sequence: LSVTGDAENQYQTLY
Position: 36-50
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ECD p18
Chemical type: Peptide from protein
Sequence: YVLVAMNEFSTLPLP
Position: 86-100
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ECD p20
Chemical type: Peptide from protein
Sequence: TLPLPNLRVVRGTQV
Position: 96-110
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ECD p36
Chemical type: Peptide from protein
Sequence: VKDNGRSCPPCHEVC
Position: 176-190
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ECD p64
Chemical type: Peptide from protein
Sequence: GLKMCEPCGGLCPKA
Position: 316-330
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ECD p70
Chemical type: Peptide from protein
Sequence: SNIDGFVNCTKILGN
Position: 346-360
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ECD p111
Chemical type: Peptide from protein
Sequence: SCHPECQPMEGTATC
Position: 551-565
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ECD p117
Chemical type: Peptide from protein
Sequence: DGPHCVSSCPHGVLG
Position: 581-595
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ICD p13
Chemical type: Peptide from protein
Sequence: KGVWIPEGESIKIPV
Position: 725-739
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ICD p25
Chemical type: Peptide from protein
Sequence: LVTQYLPLGSLLDHV
Position: 785-799
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ICD p28
Chemical type: Peptide from protein
Sequence: RQHRGALGPQLLLNW
Position: 800-814
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ICD p30
Chemical type: Peptide from protein
Sequence: LLLNWGVQIAKGMYY
Position: 810-824
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ICD p43
Chemical type: Peptide from protein
Sequence: IKWMALESIHFGKYT
Position: 875-889
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ICD p49
Chemical type: Peptide from protein
Sequence: MTFGAEPYAGLRLAE
Position: 905-919
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ICD p62
Chemical type: Peptide from protein
Sequence: RDPPRYLVIKRESGP
Position: 970-984
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ICD p75
Chemical type: Peptide from protein
Sequence: VGTLNRPRGSQSLLS
Position: 1035-1049
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ICD p84
Chemical type: Peptide from protein
Sequence: RPVSLHPMPRGCLAS
Position: 1080-1094
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ICD p87
Chemical type: Peptide from protein
Sequence: ESSEGHVTGSEAELQ
Position: 1095-1109
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ICD p88
Chemical type: Peptide from protein
Sequence: HVTGSEAELQEKVSM
Position: 1100-1114
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ICD p90
Chemical type: Peptide from protein
Sequence: EKVSMCRSRSRSRSP
Position: 1110-1124
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ICD p115
Chemical type: Peptide from protein
Sequence: LGSTQSCPLHPVPIM
Position: 1235-1249
Source molecule (GenBank): P21860.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Short Term Restimulated