LiteFold/IEDB huggingface dataset:
Reference: S A Kellermann; D J McCormick; S L Freeman; J C Morris; B M Conti-Fine. "TSH receptor sequences recognized by CD4+ T cells in Graves' disease patients and healthy controls." Journal of autoimmunity (1995).

Epitope: TSH-R (76-95)
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Positive
Host:  27-56 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TSH-R (76-95)
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Positive
Host:  24-46 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TSH-R (76-95)
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Host:  33-50 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R (331-350)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Positive
Host:  33-50 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R (331-350)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Host:  24-46 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TSH-R (331-350)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Positive
Host:  27-56 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TSH-R (376-394)
Chemical type: Peptide from protein
Sequence: VCTPKSDEFNPCEDIMGYK
Position: 397-415
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Host:  33-50 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R (376-394)
Chemical type: Peptide from protein
Sequence: VCTPKSDEFNPCEDIMGYK
Position: 397-415
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Host:  24-46 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: TSH-R (376-394)
Chemical type: Peptide from protein
Sequence: VCTPKSDEFNPCEDIMGYK
Position: 397-415
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Host:  27-56 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone
Reference: E V Nagy; J C Morris; H B Burch; S Bhatia; K Salata; K D Burman. "Thyrotropin receptor T cell epitopes in autoimmune thyroid disease." Clinical immunology and immunopathology (1995).

Epitope: TSHR (76-95)
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSHR (76-95)
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSHR (76-95)
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSHR (331-350)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSHR (331-350)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSHR (331-350)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSHR (376-394)
Chemical type: Peptide from protein
Sequence: VCTPKSDEFNPCEDIMGYK
Position: 397-415
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSHR (376-394)
Chemical type: Peptide from protein
Sequence: VCTPKSDEFNPCEDIMGYK
Position: 397-415
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSHR (376-394)
Chemical type: Peptide from protein
Sequence: VCTPKSDEFNPCEDIMGYK
Position: 397-415
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: J C Morris; J L Gibson; E J Haas; E R Bergert; J S Dallas; B S Prabhakar. "Identification of epitopes and affinity purification of thyroid stimulating auto-antibodies using synthetic human TSH receptor peptides." Autoimmunity (1994).

Epitope: TSH-R (76-95)
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: TSH-R (76-95)
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSH-R (331-350)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: TSH-R (331-350)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSH-R (376-394)
Chemical type: Peptide from protein
Sequence: VCTPKSDEFNPCEDIMGYK
Position: 397-415
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: TSH-R (376-394)
Chemical type: Peptide from protein
Sequence: VCTPKSDEFNPCEDIMGYK
Position: 397-415
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: TSH-R (376-394)
Chemical type: Peptide from protein
Sequence: VCTPKSDEFNPCEDIMGYK
Position: 397-415
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSH-R (376-394)
Chemical type: Peptide from protein
Sequence: VCTPKSDEFNPCEDIMGYK
Position: 397-415
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive
Reference: G D Chazenbalk; G Costante; S Portolano; S M McLachlan; B Rapoport. "The immunodominant region on human thyroid peroxidase recognized by autoantibodies does not contain the monoclonal antibody 47/c21 linear epitope." The Journal of clinical endocrinology and metabolism (1993).

Epitope: TPO 713-721
Chemical type: Peptide from protein
Sequence: KFPEDFESC
Position: 713-721
Source molecule (GenBank): P07202.4
Assay category: BCell
Result: Positive
Reference: E V Nagy; H B Burch; K Mahoney; Y G Lukes; J C Morris; K D Burman. "Graves' IgG recognizes linear epitopes in the human thyrotropin receptor." Biochemical and biophysical research communications (1992).

Epitope: TSHR (76-95)
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive-High

Epitope: TSHR (76-95)
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive-High

Epitope: TSHR (331-350)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: TSHR (331-350)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative

Epitope: TSHR (376-394)
Chemical type: Peptide from protein
Sequence: VCTPKSDEFNPCEDIMGYK
Position: 397-415
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive

Epitope: TSHR (376-394)
Chemical type: Peptide from protein
Sequence: VCTPKSDEFNPCEDIMGYK
Position: 397-415
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative
Reference: T Endo; M Ohmori; M Ikeda; T Onaya. "Rabbit antibodies toward extracellular loops of the membrane spanning region of human thyrotropin receptor possess thyroid stimulating activities." Biochemical and biophysical research communications (1991).

Epitope: E1 (TSH-R 478-497)
Chemical type: Peptide from protein
Sequence: HSEYYNHAIDWQTGPGCNTA
Position: 484-503
Source molecule (GenBank): BAD92444.1
Assay category: BCell
Result: Positive

Epitope: E1 (TSH-R 478-497)
Chemical type: Peptide from protein
Sequence: HSEYYNHAIDWQTGPGCNTA
Position: 484-503
Source molecule (GenBank): BAD92444.1
Assay category: BCell
Result: Positive-Low
Reference: S Kosugi; T Ban; T Akamizu; L D Kohn. "Site-directed mutagenesis of a portion of the extracellular domain of the rat thyrotropin receptor important in autoimmune thyroid disease and nonhomologous with gonadotropin receptors. Relationship of functional and immunogenic domains." The Journal of biological chemistry (1991).

Epitope: TSH-R (352-367)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFG
Position: 352-367
Source molecule (GenBank): NP_037020.1
Assay category: BCell
Result: Positive

Epitope: TSH-R (352-367)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFG
Position: 352-367
Source molecule (GenBank): NP_037020.1
Assay category: BCell
Result: Positive

Epitope: TSH-R (352-367)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFG
Position: 352-367
Source molecule (GenBank): NP_037020.1
Assay category: BCell
Result: Positive
Reference: M Murakami; M Mori. "Identification of immunogenic regions in human thyrotropin receptor for immunoglobulin G of patients with Graves' disease." Biochemical and biophysical research communications (1990).

Epitope: Peptide 1 (TSHR 13-37)
Chemical type: Peptide from protein
Sequence: HQEEDFRVTCKDIQRIPSLPPSTQT
Position: 38-62
Source molecule (GenBank): BAD92444.1
Assay category: BCell
Result: Negative

Epitope: Peptide 1 (TSHR 13-37)
Chemical type: Peptide from protein
Sequence: HQEEDFRVTCKDIQRIPSLPPSTQT
Position: 38-62
Source molecule (GenBank): BAD92444.1
Assay category: BCell
Result: Positive
Reference: Takao Ando; Rauf Latif; Terry F Davies. "Antibody-induced modulation of TSH receptor post-translational processing." The Journal of endocrinology (2007).

Epitope: TSHR (352-371)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive
Host: F 6-8 weeks

Epitope: TSHR (381-385)
Chemical type: Peptide from protein
Sequence: FDSHY
Position: 381-385
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive
Host:  6-8 weeks
Reference: Michiko Ueda; Satoshi Ichiyama; Hideo Sugawa. "Thyroid specific T helper cell analysis by ELISPOT assay with thyrotropin receptor (TSH-R) peptides." Peptides (2002).

Epitope: TSH-R (31-50)
Chemical type: Peptide from protein
Sequence: CHQEEDFRVTCKDIQRIPSL
Position: 31-50
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R (31-50)
Chemical type: Peptide from protein
Sequence: CHQEEDFRVTCKDIQRIPSL
Position: 31-50
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R (31-50)
Chemical type: Peptide from protein
Sequence: CHQEEDFRVTCKDIQRIPSL
Position: 31-50
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R (31-50)
Chemical type: Peptide from protein
Sequence: CHQEEDFRVTCKDIQRIPSL
Position: 31-50
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R (293-315)
Chemical type: Peptide from protein
Sequence: RGILESLMCNESSMQSLRQRKSV
Position: 293-315
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R (293-315)
Chemical type: Peptide from protein
Sequence: RGILESLMCNESSMQSLRQRKSV
Position: 293-315
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R (293-315)
Chemical type: Peptide from protein
Sequence: RGILESLMCNESSMQSLRQRKSV
Position: 293-315
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: TSH-R (293-315)
Chemical type: Peptide from protein
Sequence: RGILESLMCNESSMQSLRQRKSV
Position: 293-315
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: H Vlase; N Matsuoka; P N Graves; R P Magnusson; T F Davies. "Folding-dependent binding of thyrotropin (TSH) and TSH receptor autoantibodies to the murine TSH receptor ectodomain." Endocrinology (1997).

Epitope: TSHR 397-415
Chemical type: Peptide from protein
Sequence: VCTPKSDEFNPCEDIMGYK
Position: 403-421
Source molecule (GenBank): BAD92444.1
Assay category: BCell
Result: Positive
Reference: Ichiaki Ito; Nobuyoshi Mitsuoka; Junko Sobajima; Hiroko Uesugi; Shoichi Ozaki; Kazuhiko Ohya; Michiteru Yoshida. "Conformational difference in HMGB1 proteins of human neutrophils and lymphocytes revealed by epitope mapping of a monoclonal antibody." Journal of biochemistry (2004).

Epitope: Displayed peptide KSRANGGAGSIA
Chemical type: Peptide, no natural source
Sequence: KSRANGGAGSIA
Assay category: BCell
Result: Positive

Epitope: Displayed peptide KGKAGKDGGAGQ
Chemical type: Peptide, no natural source
Sequence: KGKAGKDGGAGQ
Assay category: BCell
Result: Positive
Reference: Anetta Undas; Joanna Perła; Mariusz Lacinski; Wiesław Trzeciak; Radosław Kaźmierski; Hieronim Jakubowski. "Autoantibodies against N-homocysteinylated proteins in humans: implications for atherosclerosis." Stroke; a journal of cerebral circulation (2004).

Epitope: Nα-Ac-Lys
Chemical type: Peptide, no natural source
Sequence: K
Assay category: BCell
Result: Negative
Reference: Ulrich J H Sachs; Sentot Santoso; Lida Röder; Elizabeth Smart; Gregor Bein; Hartmut Kroll. "Diclofenac-induced antibodies against red blood cells are heterogeneous and recognize different epitopes." Transfusion (2004).

Epitope: 4'-methoxy-Diclofenac (metabolite 5)
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Reference: Renaud A Du Pasquier; Marcelo J Kuroda; Yue Zheng; Jims Jean-Jacques; Norman L Letvin; Igor J Koralnik. "A prospective study demonstrates an association between JC virus-specific cytotoxic T lymphocytes and the early control of progressive multifocal leukoencephalopathy." Brain : a journal of neurology (2004).

Epitope: VP1<sub>p100</sub>
Chemical type: Peptide from protein
Sequence: ILMWEAVTL
Position: 100-108
Source molecule (GenBank): AAL37677.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: VP1<sub>p100</sub>
Chemical type: Peptide from protein
Sequence: ILMWEAVTL
Position: 100-108
Source molecule (GenBank): AAL37677.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Short Term Restimulated
Reference: D Cavill; S A Waterman; T P Gordon. "Antibodies raised against the second extracellular loop of the human muscarinic M3 receptor mimic functional autoantibodies in Sjögren's syndrome." Scandinavian journal of immunology (2004).

Epitope: Human M3R (208-227)
Chemical type: Peptide from protein
Sequence: QYFVGKRTVPPGECFIQFLS
Position: 208-227
Source molecule (GenBank): AAK68114.1
Assay category: BCell
Result: Positive-Low

Epitope: Human M3R (208-227)
Chemical type: Peptide from protein
Sequence: QYFVGKRTVPPGECFIQFLS
Position: 208-227
Source molecule (GenBank): AAK68114.1
Assay category: BCell
Result: Positive

Epitope: Human M3R (213-237)
Chemical type: Peptide from protein
Sequence: KRTVPPGECFIQFLSEPTITFGTAI
Position: 213-237
Source molecule (GenBank): AAK68114.1
Assay category: BCell
Result: Positive

Epitope: Human M3R (213-237)
Chemical type: Peptide from protein
Sequence: KRTVPPGECFIQFLSEPTITFGTAI
Position: 213-237
Source molecule (GenBank): AAK68114.1
Assay category: BCell
Result: Positive
Reference: T Olee; J M Powers; S W Brostoff. "A T cell epitope for experimental allergic neuritis." Journal of neuroimmunology (1988).

Epitope: P2 60-81
Chemical type: Peptide from protein
Sequence: TEISFKLGQEFEETTADNRKTK
Position: 61-82
Source molecule (GenBank): NP_001068707.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: P2 60-81
Chemical type: Peptide from protein
Sequence: TEISFKLGQEFEETTADNRKTK
Position: 61-82
Source molecule (GenBank): NP_001068707.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone

Epitope: P2 60-81
Chemical type: Peptide from protein
Sequence: TEISFKLGQEFEETTADNRKTK
Position: 61-82
Source molecule (GenBank): NP_001068707.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks

Epitope: P2 60-81
Chemical type: Peptide from protein
Sequence: TEISFKLGQEFEETTADNRKTK
Position: 61-82
Source molecule (GenBank): NP_001068707.1
Assay category: TCell
Result: Positive

Epitope: P2 60-81
Chemical type: Peptide from protein
Sequence: TEISFKLGQEFEETTADNRKTK
Position: 61-82
Source molecule (GenBank): NP_001068707.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Cell Line / Clone
Reference: T Olee; H C Powell; S W Brostoff. "New minimum length requirement for a T cell epitope for experimental allergic neuritis." Journal of neuroimmunology (1990).

Epitope: P2 (60-70)
Chemical type: Peptide from protein
Sequence: TEISFKLGQEF
Position: 61-71
Source molecule (GenBank): NP_001068707.1
Assay category: TCell
Result: Positive
Host:  8-12 weeks
Reference: D Wymann; M Blüggel; H Kalbacher; T Blesken; C A Akdis; H E Meyer; K Blaser. "Human B cells secrete migration inhibition factor (MIF) and present a naturally processed MIF peptide on HLA-DRB1*0405 by a FXXL motif." Immunology (1999).

Epitope: Secretory granule core protein 28-42
Chemical type: Peptide from protein
Sequence: YPTQRARYQWVRCNP
Position: 28-42
Source molecule (GenBank): AAA60322.1
Assay category: MhcLigandElution
Result: Positive
Reference: K Bartnes; F Leon; J P Briand; P J Travers; K Hannestad. "N-terminal elongation of a peptide determinant beyond the first primary anchor improves binding to H-2 I-Ad and HLA-DR1 by backbone-dependent and aromatic side chain-dependent interactions, respectively." European journal of immunology (1999).

Epitope: g2a<sup>b</sup> 436-451 (F436K)
Chemical type: Peptide, no natural source
Sequence: KMYSKLRVQKSTWERG
Assay category: MhcBinding
Result: Positive

Epitope: g2a<sup>b</sup> 435-451 (Y435F)
Chemical type: Peptide, no natural source
Sequence: FFMYSKLRVQKSTWERG
Assay category: MhcBinding
Result: Positive
Reference: K C Faé; S E Oshiro; A Toubert; D Charron; J Kalil; L Guilherme. "How an autoimmune reaction triggered by molecular mimicry between streptococcal M protein and cardiac tissue proteins leads to heart lesions in rheumatic heart disease." Journal of autoimmunity (2005).

Epitope: M5 (83-103)
Chemical type: Peptide from protein
Sequence: LKQQRDTLSTQKETLEREVQN
Position: 98-118
Source molecule (GenBank): CAI77246.1
Assay category: TCell
Result: Positive
MHC allele types: 353 330 345 347
Host: M 10 years
Cell type: T cell CD4+
Tissue: heart
Culture conditions: Cell Line / Clone
Reference: Xavier Saulquin; Emmanuel Scotet; Lydie Trautmann; Marie-Alix Peyrat; Franck Halary; Marc Bonneville; Elisabeth Houssaint. "+1 Frameshifting as a novel mechanism to generate a cryptic cytotoxic T lymphocyte epitope derived from human interleukin 10." The Journal of experimental medicine (2002).

Epitope: IL-10 Frameshift 1
Chemical type: Peptide, no natural source
Sequence: HRFLPVKTR
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: synovial fluid
Culture conditions: Cell Line / Clone

Epitope: IL-10 Frameshift 1
Chemical type: Peptide, no natural source
Sequence: HRFLPVKTR
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: synovial fluid
Culture conditions: Cell Line / Clone
Reference: Elias N Glaros; Chris T Turner; Emma J Parkinson; John J Hopwood; Doug A Brooks. "Immune response to enzyme replacement therapy: single epitope control of antigen distribution from circulation." Molecular genetics and metabolism (2002).

Epitope: α-L-Iduronidase p81
Chemical type: Peptide from protein
Sequence: CSPDGEWRRLGR
Position: 481-492
Source molecule (GenBank): AAA51698.1
Assay category: BCell
Result: Positive

Epitope: α-L-Iduronidase p82
Chemical type: Peptide from protein
Sequence: WRRLGRPVFPTA
Position: 487-498
Source molecule (GenBank): AAA51698.1
Assay category: BCell
Result: Positive
Reference: A A Ansari; N Neckelmann; F Villinger; P Leung; D J Danner; S S Brar; S Zhao; M B Gravanis; A Mayne; M E Gershwin. "Epitope mapping of the branched chain alpha-ketoacid dehydrogenase dihydrolipoyl transacylase (BCKD-E2) protein that reacts with sera from patients with idiopathic dilated cardiomyopathy." Journal of immunology (Baltimore, Md. : 1950) (1994).

Epitope: BCKD-LBD
Chemical type: Peptide from protein
Sequence: CEVQSDKASVTITSRYDGVI
Position: 99-118
Source molecule (GenBank): CAH72258.1
Assay category: BCell
Result: Negative

Epitope: BCKD-LBD
Chemical type: Peptide from protein
Sequence: CEVQSDKASVTITSRYDGVI
Position: 99-118
Source molecule (GenBank): CAH72258.1
Assay category: BCell
Result: Negative

Epitope: BCKD-LBD
Chemical type: Peptide from protein
Sequence: CEVQSDKASVTITSRYDGVI
Position: 99-118
Source molecule (GenBank): CAH72258.1
Assay category: BCell
Result: Negative
Reference: Eystein S Husebye; Eirik Bratland; Geir Bredholt; Mati Fridkin; Molly Dayan; Edna Mozes. "The substrate-binding domain of 21-hydroxylase, the main autoantigen in autoimmune Addison's disease, is an immunodominant T cell epitope." Endocrinology (2006).

Epitope: 21OH (385-393)
Chemical type: Peptide from protein
Sequence: IPNLQGAHL
Position: 386-394
Source molecule (GenBank): NP_000491.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: 21OH (385-393)
Chemical type: Peptide from protein
Sequence: IPNLQGAHL
Position: 386-394
Source molecule (GenBank): NP_000491.2
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: lymph node cells
Tissue: lymph node
Culture conditions: Direct Ex Vivo