Reference: Rajesh Singh; Shailesh Singh; Praveen K Sharma; Udai P Singh; David E Briles; Susan K Hollingshead; James W Lillard. "Helper T cell epitope-mapping reveals MHC-peptide binding affinities that correlate with T helper cell responses to pneumococcal surface protein A." PloS one (2010).

Epitope: PspA peptide 17
Chemical type: Peptide from protein
Sequence: LEEAKAKLEEAEKKA
Position: 177-191
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 17
Chemical type: Peptide from protein
Sequence: LEEAKAKLEEAEKKA
Position: 177-191
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 17
Chemical type: Peptide from protein
Sequence: LEEAKAKLEEAEKKA
Position: 177-191
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 17
Chemical type: Peptide from protein
Sequence: LEEAKAKLEEAEKKA
Position: 177-191
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 17
Chemical type: Peptide from protein
Sequence: LEEAKAKLEEAEKKA
Position: 177-191
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 17
Chemical type: Peptide from protein
Sequence: LEEAKAKLEEAEKKA
Position: 177-191
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 19
Chemical type: Peptide from protein
Sequence: DAEEVAPQAKIAELE
Position: 199-213
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive-High
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 19
Chemical type: Peptide from protein
Sequence: DAEEVAPQAKIAELE
Position: 199-213
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive-High
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 19
Chemical type: Peptide from protein
Sequence: DAEEVAPQAKIAELE
Position: 199-213
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive-High
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 19
Chemical type: Peptide from protein
Sequence: DAEEVAPQAKIAELE
Position: 199-213
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive-High
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 19
Chemical type: Peptide from protein
Sequence: DAEEVAPQAKIAELE
Position: 199-213
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive-High
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 19
Chemical type: Peptide from protein
Sequence: DAEEVAPQAKIAELE
Position: 199-213
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 22
Chemical type: Peptide from protein
Sequence: EDYAKEGFRAPLQSK
Position: 232-246
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 22
Chemical type: Peptide from protein
Sequence: EDYAKEGFRAPLQSK
Position: 232-246
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive-High
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 22
Chemical type: Peptide from protein
Sequence: EDYAKEGFRAPLQSK
Position: 232-246
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 22
Chemical type: Peptide from protein
Sequence: EDYAKEGFRAPLQSK
Position: 232-246
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 22
Chemical type: Peptide from protein
Sequence: EDYAKEGFRAPLQSK
Position: 232-246
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive-High
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 22
Chemical type: Peptide from protein
Sequence: EDYAKEGFRAPLQSK
Position: 232-246
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 23
Chemical type: Peptide from protein
Sequence: LQSKLDAKKAKLSKL
Position: 243-257
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 23
Chemical type: Peptide from protein
Sequence: LQSKLDAKKAKLSKL
Position: 243-257
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive-High
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 23
Chemical type: Peptide from protein
Sequence: LQSKLDAKKAKLSKL
Position: 243-257
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 23
Chemical type: Peptide from protein
Sequence: LQSKLDAKKAKLSKL
Position: 243-257
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 23
Chemical type: Peptide from protein
Sequence: LQSKLDAKKAKLSKL
Position: 243-257
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 23
Chemical type: Peptide from protein
Sequence: LQSKLDAKKAKLSKL
Position: 243-257
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive-High
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 24
Chemical type: Peptide from protein
Sequence: LSKLEELSDKIDELD
Position: 254-268
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 24
Chemical type: Peptide from protein
Sequence: LSKLEELSDKIDELD
Position: 254-268
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 24
Chemical type: Peptide from protein
Sequence: LSKLEELSDKIDELD
Position: 254-268
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 24
Chemical type: Peptide from protein
Sequence: LSKLEELSDKIDELD
Position: 254-268
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 24
Chemical type: Peptide from protein
Sequence: LSKLEELSDKIDELD
Position: 254-268
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 24
Chemical type: Peptide from protein
Sequence: LSKLEELSDKIDELD
Position: 254-268
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 31
Chemical type: Peptide from protein
Sequence: APEAPAEQPKPAPAP
Position: 331-345
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 31
Chemical type: Peptide from protein
Sequence: APEAPAEQPKPAPAP
Position: 331-345
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 31
Chemical type: Peptide from protein
Sequence: APEAPAEQPKPAPAP
Position: 331-345
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 31
Chemical type: Peptide from protein
Sequence: APEAPAEQPKPAPAP
Position: 331-345
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 31
Chemical type: Peptide from protein
Sequence: APEAPAEQPKPAPAP
Position: 331-345
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 31
Chemical type: Peptide from protein
Sequence: APEAPAEQPKPAPAP
Position: 331-345
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 51
Chemical type: Peptide from protein
Sequence: WYYLNANGAMATGWV
Position: 551-565
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 51
Chemical type: Peptide from protein
Sequence: WYYLNANGAMATGWV
Position: 551-565
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 51
Chemical type: Peptide from protein
Sequence: WYYLNANGAMATGWV
Position: 551-565
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Positive
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 51
Chemical type: Peptide from protein
Sequence: WYYLNANGAMATGWV
Position: 551-565
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 51
Chemical type: Peptide from protein
Sequence: WYYLNANGAMATGWV
Position: 551-565
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: PspA peptide 51
Chemical type: Peptide from protein
Sequence: WYYLNANGAMATGWV
Position: 551-565
Source molecule (GenBank): YP_815641.1
Assay category: TCell
Result: Negative
Host: F 8-12 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo