Reference: Federica Bianchi; Daniele Veggi; Laura Santini; Francesca Buricchi; Erika Bartolini; Paola Lo Surdo; Manuele Martinelli; Oretta Finco; Vega Masignani; Matthew J Bottomley; Domenico Maione; Roberta Cozzi. "Cocrystal structure of meningococcal factor H binding protein variant 3 reveals a new crossprotective epitope recognized by human mAb 1E6." FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2019).

Epitope: mAb 1E6 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S73, A74, Q75, G76, E78, K99, R102, D104, F105, V106, S120, E122, E139, K140, L150, N152, R154, D186, D187, P188, N189, K211
Source molecule (GenBank): ABF82029.1
Assay category: BCell
Result: Positive
Host:  adult

Epitope: mAb 1E6 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S73, A74, Q75, G76, E78, K99, R102, D104, F105, V106, S120, E122, E139, K140, L150, N152, R154, D186, D187, P188, N189, K211
Source molecule (GenBank): ABF82029.1
Assay category: BCell
Result: Positive
Quantitative measurement: 52500000
Host:  adult

Epitope: mAb 1E6 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S73, A74, Q75, G76, E78, K99, R102, D104, F105, V106, S120, E122, E139, K140, L150, N152, R154, D186, D187, P188, N189, K211
Source molecule (GenBank): ABF82029.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.014
Host:  adult

Epitope: mAb 1E6 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S73, A74, Q75, G76, E78, K99, R102, D104, F105, V106, S120, E122, E139, K140, L150, N152, R154, D186, D187, P188, N189, K211
Source molecule (GenBank): ABF82029.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.265
Host:  adult

Epitope: mAb 1E6 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S73, A74, Q75, G76, E78, K99, R102, D104, F105, V106, S120, E122, E139, K140, L150, N152, R154, D186, D187, P188, N189, K211
Source molecule (GenBank): ABF82029.1
Assay category: BCell
Result: Positive
Quantitative measurement: 120000.0
Host:  adult

Epitope: mAb 1E6 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S73, A74, Q75, G76, E78, K99, R102, D104, F105, V106, S120, E122, E139, K140, L150, N152, R154, D186, D187, P188, N189, K211
Source molecule (GenBank): ABF82029.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.036
Host:  adult

Epitope: mAb 1E6 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S73, A74, Q75, G76, E78, K99, R102, D104, F105, V106, S120, E122, E139, K140, L150, N152, R154, D186, D187, P188, N189, K211
Source molecule (GenBank): ABF82029.1
Assay category: BCell
Result: Positive
Quantitative measurement: 570000.0
Host:  adult

Epitope: mAb 1E6 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S73, A74, Q75, G76, E78, K99, R102, D104, F105, V106, S120, E122, E139, K140, L150, N152, R154, D186, D187, P188, N189, K211
Source molecule (GenBank): ABF82029.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.0013
Host:  adult

Epitope: mAb 1E6 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S73, A74, Q75, G76, E78, K99, R102, D104, F105, V106, S120, E122, E139, K140, L150, N152, R154, D186, D187, P188, N189, K211
Source molecule (GenBank): ABF82029.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.7
Host:  adult

Epitope: mAb 1E6 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S73, A74, Q75, G76, E78, K99, R102, D104, F105, V106, S120, E122, E139, K140, L150, N152, R154, D186, D187, P188, N189, K211
Source molecule (GenBank): ABF82029.1
Assay category: BCell
Result: Positive
Host:  adult

Epitope: mAb 1E6 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S73, A74, Q75, G76, E78, K99, R102, D104, F105, V106, S120, E122, E139, K140, L150, N152, R154, D186, D187, P188, N189, K211
Source molecule (GenBank): ABF82029.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.65
Host:  adult

Epitope: mAb 1E6 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S73, A74, Q75, G76, E78, K99, R102, D104, F105, V106, S120, E122, E139, K140, L150, N152, R154, D186, D187, P188, N189, K211
Source molecule (GenBank): ABF82029.1
Assay category: BCell
Result: Positive
Host:  adult

Epitope: mAb 1E6 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S73, A74, Q75, G76, E78, K99, R102, D104, F105, V106, S120, E122, E139, K140, L150, N152, R154, D186, D187, P188, N189, K211
Source molecule (GenBank): ABF82029.1
Assay category: BCell
Result: Positive
Host:  adult

Epitope: mAb 1E6 epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: S73, A74, Q75, G76, E78, K99, R102, D104, F105, V106, S120, E122, E139, K140, L150, N152, R154, D186, D187, P188, N189, K211
Source molecule (GenBank): ABF82029.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.00043
Host:  adult