Reference: Sergio Gonzalez-Duque; Marie Eliane Azoury; Maikel L Colli; Georgia Afonso; Jean-Valery Turatsinze; Laura Nigi; Ana Ines Lalanne; Guido Sebastiani; Alexia Carré; Sheena Pinto; Slobodan Culina; Noémie Corcos; Marco Bugliani; Piero Marchetti; Mathieu Armanet; Marc Diedisheim; Bruno Kyewski; Lars M Steinmetz; Søren Buus; Sylvaine You; Daniele Dubois-Laforgue; Etienne Larger; Jean-Paul Beressi; Graziella Bruno; Francesco Dotta; Raphael Scharfmann; Decio L Eizirik; Yann Verdier; Joelle Vinh; Roberto Mallone. "Conventional and Neo-antigenic Peptides Presented by β Cells Are Targeted by Circulating Naïve CD8+ T Cells in Type 1 Diabetic and Healthy Donors." Cell metabolism (2018).

Epitope: AEFNRIM(+15.99)SL
Chemical type: Peptide from protein
Sequence: AEFNRIMSL
Position: 804-812
Source molecule (GenBank): 1015190665
Assay category: MhcLigandElution
Result: Positive

Epitope: AEFPLEPM(+15.99)L
Chemical type: Peptide from protein
Sequence: AEFPLEPML
Position: 979-987
Source molecule (GenBank): 1016080622
Assay category: MhcLigandElution
Result: Positive

Epitope: ATGDM(+15.99)SGLLK
Chemical type: Peptide from protein
Sequence: ATGDMSGLLK
Position: 18-27
Source molecule (GenBank): 39644832
Assay category: MhcLigandElution
Result: Positive

Epitope: EAEDLQVGQVE
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVE
Position: 57-67
Source molecule (GenBank): 4557671
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 143 211 28 38 308 1

Epitope: FEGRELLVI
Chemical type: Peptide from protein
Sequence: FEGRELLVI
Position: 83-91
Source molecule (GenBank): 4503009
Assay category: MhcLigandElution
Result: Positive

Epitope: FEGRELLVI
Chemical type: Peptide from protein
Sequence: FEGRELLVI
Position: 83-91
Source molecule (GenBank): 4503009
Assay category: MhcLigandElution
Result: Positive

Epitope: FSKIQQNFQ
Chemical type: Peptide from protein
Sequence: FSKIQQNFQ
Position: 143-151
Source molecule (GenBank): 33392684
Assay category: MhcLigandElution
Result: Positive

Epitope: GEFTHEM(+15.99)QV
Chemical type: Peptide from protein
Sequence: GEFTHEMQV
Position: 322-330
Source molecule (GenBank): 37998955
Assay category: MhcLigandElution
Result: Positive

Epitope: GEVKGFLRV
Chemical type: Peptide from protein
Sequence: GEVKGFLRV
Position: 911-919
Source molecule (GenBank): 1057866897
Assay category: MhcLigandElution
Result: Positive

Epitope: GPR119 48-56
Chemical type: Peptide from protein
Sequence: AVADTLIGV
Position: 48-56
Source molecule (GenBank): 71682812
Assay category: TCell
Result: Negative
Host:  22-45 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GPR119 48-56
Chemical type: Peptide from protein
Sequence: AVADTLIGV
Position: 48-56
Source molecule (GenBank): 71682812
Assay category: MhcLigandElution
Result: Positive

Epitope: IEDRPM(+15.99)PKL
Chemical type: Peptide from protein
Sequence: IEDRPMPKL
Position: 745-753
Source molecule (GenBank): 2992634
Assay category: MhcLigandElution
Result: Positive

Epitope: LEAGLPLQV
Chemical type: Peptide from protein
Sequence: LEAGLPLQV
Position: 350-358
Source molecule (GenBank): 40225646
Assay category: MhcLigandElution
Result: Positive

Epitope: LEAGLPLQV
Chemical type: Peptide from protein
Sequence: LEAGLPLQV
Position: 350-358
Source molecule (GenBank): 40225646
Assay category: MhcLigandElution
Result: Positive

Epitope: LEKEEFVTL
Chemical type: Peptide from protein
Sequence: LEKEEFVTL
Position: 299-307
Source molecule (GenBank): 343780850
Assay category: MhcLigandElution
Result: Positive

Epitope: NRVTGVYEL
Chemical type: Peptide from protein
Sequence: NRVTGVYEL
Position: 1353-1361
Source molecule (GenBank): 1057866897
Assay category: MhcLigandElution
Result: Positive

Epitope: QLYW(+15.99)SH(+15.99)PRK
Chemical type: Peptide from protein
Sequence: QLYWSH
Position: 5-10
Source molecule (GenBank): 71772583
Assay category: MhcLigandElution
Result: Positive

Epitope: RLLPLLALL
Chemical type: Peptide from protein
Sequence: RLLPLLALL
Position: 6-14
Source molecule (GenBank): 114318995
Assay category: MhcLigandElution
Result: Positive

Epitope: RLPQPPVGK
Chemical type: Peptide from protein
Sequence: RLPQPPVGK
Position: 156-164
Source molecule (GenBank): 4506321
Assay category: MhcLigandElution
Result: Positive

Epitope: RM(+15.99)LAQQAVK
Chemical type: Peptide from protein
Sequence: RMLAQQAVK
Position: 619-627
Source molecule (GenBank): 1024249277
Assay category: MhcLigandElution
Result: Positive

Epitope: RRTAQVRYL
Chemical type: Peptide from protein
Sequence: RRTAQVRYL
Position: 166-174
Source molecule (GenBank): 6179738
Assay category: MhcLigandElution
Result: Positive

Epitope: RTM(+15.99)SEAALVRK
Chemical type: Peptide from protein
Sequence: RTMSEAALVRK
Position: 140-150
Source molecule (GenBank): 393715063
Assay category: MhcLigandElution
Result: Positive

Epitope: RVAQLDQLLHY
Chemical type: Peptide from protein
Sequence: RVAQLDQLLHY
Position: 603-613
Source molecule (GenBank): 12653215
Assay category: MhcLigandElution
Result: Positive

Epitope: SLLERVLMK
Chemical type: Peptide from protein
Sequence: SLLERVLMK
Position: 777-785
Source molecule (GenBank): 148839284
Assay category: MhcLigandElution
Result: Positive

Epitope: YLQGQRLDNVV
Chemical type: Peptide from protein
Sequence: YLQGQRLDNVV
Position: 186-196
Source molecule (GenBank): 13529158
Assay category: MhcLigandElution
Result: Positive

Epitope: CLDN7-008 60-68
Chemical type: Peptide from protein
Sequence: GMMSCKIGL
Assay category: TCell
Result: Negative
Host:  22-45 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GNAS-036 185-194
Chemical type: Peptide from protein
Sequence: QLIDCAQYFL
Position: 156-165
Source molecule (GenBank): 18426900
Assay category: TCell
Result: Negative
Host:  22-45 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LARP4-006 355-363
Chemical type: Peptide from protein
Sequence: YLQKETSTL
Position: 355-363
Source molecule (GenBank): 1370461098
Assay category: TCell
Result: Positive
Host:  22-45 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PTPRN2-005 19-27
Chemical type: Peptide from protein
Sequence: VLPAAPSSV
Position: 19-27
Source molecule (GenBank): 1620664
Assay category: TCell
Result: Positive
Host:  22-45 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: ALWGPD/KPVN
Chemical type: Spliced peptide from proteins
Position: 6-11
Source molecule (GenBank): Q9UEG4.2
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 143 211 28 38 308 1

Epitope: SVLLT/RLAK
Chemical type: Spliced peptide from proteins
Position: 1379-1383
Source molecule (GenBank): A0JNW5.2
Assay category: MhcLigandElution
Result: Positive