Reference: Isabelle Auger; Nathalie Balandraud; Emmanuel Massy; Marie F Hemon; Elisa Peen; Fanny Arnoux; Charlotte Mariot; Marielle Martin; Pierre Lafforgue; Jean-Marc Busnel; Jean Roudier. "Peptidylarginine Deiminase Autoimmunity and the Development of Anti-Citrullinated Protein Antibody in Rheumatoid Arthritis: The Hapten-Carrier Model." Arthritis & rheumatology (Hoboken, N.J.) (2020).

Epitope: PAD4 P3
Chemical type: Peptide from protein
Sequence: LGTLTQLDICSSAPEDCTSF
Position: 21-40
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P3
Chemical type: Peptide from protein
Sequence: LGTLTQLDICSSAPEDCTSF
Position: 21-40
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P3
Chemical type: Peptide from protein
Sequence: LGTLTQLDICSSAPEDCTSF
Position: 21-40
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P3
Chemical type: Peptide from protein
Sequence: LGTLTQLDICSSAPEDCTSF
Position: 21-40
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P3
Chemical type: Peptide from protein
Sequence: LGTLTQLDICSSAPEDCTSF
Position: 21-40
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P20
Chemical type: Peptide from protein
Sequence: KDFFTNHTLVLHVARSEMDK
Position: 191-210
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P20
Chemical type: Peptide from protein
Sequence: KDFFTNHTLVLHVARSEMDK
Position: 191-210
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P20
Chemical type: Peptide from protein
Sequence: KDFFTNHTLVLHVARSEMDK
Position: 191-210
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P20
Chemical type: Peptide from protein
Sequence: KDFFTNHTLVLHVARSEMDK
Position: 191-210
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P20
Chemical type: Peptide from protein
Sequence: KDFFTNHTLVLHVARSEMDK
Position: 191-210
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P22
Chemical type: Peptide from protein
Sequence: VRVFQATRGKLSSKCSVVLG
Position: 211-230
Source molecule (GenBank): NP_036519.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PAD4 P22
Chemical type: Peptide from protein
Sequence: VRVFQATRGKLSSKCSVVLG
Position: 211-230
Source molecule (GenBank): NP_036519.2
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PAD4 P22
Chemical type: Peptide from protein
Sequence: VRVFQATRGKLSSKCSVVLG
Position: 211-230
Source molecule (GenBank): NP_036519.2
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PAD4 P22
Chemical type: Peptide from protein
Sequence: VRVFQATRGKLSSKCSVVLG
Position: 211-230
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P22
Chemical type: Peptide from protein
Sequence: VRVFQATRGKLSSKCSVVLG
Position: 211-230
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Positive

Epitope: PAD4 P22
Chemical type: Peptide from protein
Sequence: VRVFQATRGKLSSKCSVVLG
Position: 211-230
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P22
Chemical type: Peptide from protein
Sequence: VRVFQATRGKLSSKCSVVLG
Position: 211-230
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P22
Chemical type: Peptide from protein
Sequence: VRVFQATRGKLSSKCSVVLG
Position: 211-230
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P35
Chemical type: Peptide from protein
Sequence: ENMDDQWMQDEMEIGYIQAP
Position: 341-360
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P35
Chemical type: Peptide from protein
Sequence: ENMDDQWMQDEMEIGYIQAP
Position: 341-360
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P35
Chemical type: Peptide from protein
Sequence: ENMDDQWMQDEMEIGYIQAP
Position: 341-360
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P35
Chemical type: Peptide from protein
Sequence: ENMDDQWMQDEMEIGYIQAP
Position: 341-360
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P35
Chemical type: Peptide from protein
Sequence: ENMDDQWMQDEMEIGYIQAP
Position: 341-360
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P36
Chemical type: Peptide from protein
Sequence: EMEIGYIQAPHKTLPVVFDS
Position: 351-370
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P36
Chemical type: Peptide from protein
Sequence: EMEIGYIQAPHKTLPVVFDS
Position: 351-370
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P36
Chemical type: Peptide from protein
Sequence: EMEIGYIQAPHKTLPVVFDS
Position: 351-370
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P36
Chemical type: Peptide from protein
Sequence: EMEIGYIQAPHKTLPVVFDS
Position: 351-370
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P36
Chemical type: Peptide from protein
Sequence: EMEIGYIQAPHKTLPVVFDS
Position: 351-370
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P40
Chemical type: Peptide from protein
Sequence: YVTRGPQTGGISGLDSFGNL
Position: 391-410
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P40
Chemical type: Peptide from protein
Sequence: YVTRGPQTGGISGLDSFGNL
Position: 391-410
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P40
Chemical type: Peptide from protein
Sequence: YVTRGPQTGGISGLDSFGNL
Position: 391-410
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P40
Chemical type: Peptide from protein
Sequence: YVTRGPQTGGISGLDSFGNL
Position: 391-410
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P40
Chemical type: Peptide from protein
Sequence: YVTRGPQTGGISGLDSFGNL
Position: 391-410
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P64
Chemical type: Peptide from protein
Sequence: NDFFTYHIRHGEVHCGTNVR
Position: 631-650
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P64
Chemical type: Peptide from protein
Sequence: NDFFTYHIRHGEVHCGTNVR
Position: 631-650
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P64
Chemical type: Peptide from protein
Sequence: NDFFTYHIRHGEVHCGTNVR
Position: 631-650
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P64
Chemical type: Peptide from protein
Sequence: NDFFTYHIRHGEVHCGTNVR
Position: 631-650
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative

Epitope: PAD4 P64
Chemical type: Peptide from protein
Sequence: NDFFTYHIRHGEVHCGTNVR
Position: 631-650
Source molecule (GenBank): NP_036519.2
Assay category: MhcBinding
Result: Negative