Reference: Jon A Kenniston; Brandy M Taylor; Gregory P Conley; Janja Cosic; Kris J Kopacz; Allison P Lindberg; Stephen R Comeau; Kateri Atkins; Jameson Bullen; Christopher TenHoor; Burt A Adelman; Daniel J Sexton; Thomas E Edwards; Andrew E Nixon. "Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody." The Journal of biological chemistry (2017).

Epitope: Epitope of DX-2507 Fab on soluble human FcRn/ß2m
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L105, G106, G107, K108, G109, Y111, L135, N136, G152, D153, W154, P155, E156, L158; B: I21, Q22, V105
Source molecule (GenBank): P55899.1
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000278

Epitope: Epitope of DX-2507 Fab on soluble human FcRn/ß2m
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L105, G106, G107, K108, G109, Y111, L135, N136, G152, D153, W154, P155, E156, L158; B: I21, Q22, V105
Source molecule (GenBank): P55899.1
Assay category: BCell
Result: Positive

Epitope: Epitope of DX-2507 Fab on soluble human FcRn/ß2m
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L105, G106, G107, K108, G109, Y111, L135, N136, G152, D153, W154, P155, E156, L158; B: I21, Q22, V105
Source molecule (GenBank): P55899.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.71

Epitope: Epitope of DX-2507 Fab on soluble human FcRn/ß2m
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L105, G106, G107, K108, G109, Y111, L135, N136, G152, D153, W154, P155, E156, L158; B: I21, Q22, V105
Source molecule (GenBank): P55899.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 397.0

Epitope: Epitope of DX-2507 Fab on soluble human FcRn/ß2m
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L105, G106, G107, K108, G109, Y111, L135, N136, G152, D153, W154, P155, E156, L158; B: I21, Q22, V105
Source molecule (GenBank): P55899.1
Assay category: BCell
Result: Positive
Quantitative measurement: 5.5

Epitope: Epitope of DX-2507 Fab on soluble human FcRn/ß2m
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L105, G106, G107, K108, G109, Y111, L135, N136, G152, D153, W154, P155, E156, L158; B: I21, Q22, V105
Source molecule (GenBank): P55899.1
Assay category: BCell
Result: Positive
Quantitative measurement: 4.2

Epitope: Epitope of DX-2507 Fab on soluble human FcRn/ß2m
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L105, G106, G107, K108, G109, Y111, L135, N136, G152, D153, W154, P155, E156, L158; B: I21, Q22, V105
Source molecule (GenBank): P55899.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.5

Epitope: Epitope of DX-2507 Fab on soluble human FcRn/ß2m
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L105, G106, G107, K108, G109, Y111, L135, N136, G152, D153, W154, P155, E156, L158; B: I21, Q22, V105
Source molecule (GenBank): P55899.1
Assay category: BCell
Result: Positive
Quantitative measurement: 1.95

Epitope: Epitope of DX-2507 Fab on soluble human FcRn/ß2m
Chemical type: Region on multi-chain protein
Discontinuous residues: A: L105, G106, G107, K108, G109, Y111, L135, N136, G152, D153, W154, P155, E156, L158; B: I21, Q22, V105
Source molecule (GenBank): P55899.1
Assay category: BCell
Result: Positive
Quantitative measurement: 142000.0