Reference: Menno van Lummel; Gaby Duinkerken; Peter A van Veelen; Arnoud de Ru; Robert Cordfunke; Arnaud Zaldumbide; Iria Gomez-Touriño; Sefina Arif; Mark Peakman; Jan W Drijfhout; Bart O Roep. "Posttranslational modification of HLA-DQ binding islet autoantigens in type 1 diabetes." Diabetes (2014).

Epitope: Znt-8 P2
Chemical type: Peptide from protein
Sequence: ANIVLTVVLHQRC
Position: 139-151
Source molecule (GenBank): 148342457
Assay category: MhcBinding
Result: Negative

Epitope: Znt-8 P2
Chemical type: Peptide from protein
Sequence: ANIVLTVVLHQRC
Position: 139-151
Source molecule (GenBank): 148342457
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 1200.0

Epitope: Znt-8 P2
Chemical type: Peptide from protein
Sequence: ANIVLTVVLHQRC
Position: 139-151
Source molecule (GenBank): 148342457
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 12000.0

Epitope: Znt-8 P2
Chemical type: Peptide from protein
Sequence: ANIVLTVVLHQRC
Position: 139-151
Source molecule (GenBank): 148342457
Assay category: MhcBinding
Result: Negative

Epitope: IA-2 P1
Chemical type: Peptide from protein
Sequence: CIQDGLFGQCQVG
Position: 53-65
Source molecule (GenBank): 4506321
Assay category: MhcBinding
Result: Negative

Epitope: IA-2 P1
Chemical type: Peptide from protein
Sequence: CIQDGLFGQCQVG
Position: 53-65
Source molecule (GenBank): 4506321
Assay category: MhcBinding
Result: Positive-Intermediate
Quantitative measurement: 4900.0

Epitope: IA-2 P1
Chemical type: Peptide from protein
Sequence: CIQDGLFGQCQVG
Position: 53-65
Source molecule (GenBank): 4506321
Assay category: MhcBinding
Result: Negative

Epitope: IA-2 P1
Chemical type: Peptide from protein
Sequence: CIQDGLFGQCQVG
Position: 53-65
Source molecule (GenBank): 4506321
Assay category: MhcBinding
Result: Negative

Epitope: IA-2 P10
Chemical type: Peptide from protein
Sequence: DPRMPAYIATQGP
Position: 774-786
Source molecule (GenBank): 4506321
Assay category: MhcBinding
Result: Negative

Epitope: IA-2 P10
Chemical type: Peptide from protein
Sequence: DPRMPAYIATQGP
Position: 774-786
Source molecule (GenBank): 4506321
Assay category: MhcBinding
Result: Negative

Epitope: IA-2 P10
Chemical type: Peptide from protein
Sequence: DPRMPAYIATQGP
Position: 774-786
Source molecule (GenBank): 4506321
Assay category: MhcBinding
Result: Negative

Epitope: IA-2 P10
Chemical type: Peptide from protein
Sequence: DPRMPAYIATQGP
Position: 774-786
Source molecule (GenBank): 4506321
Assay category: MhcBinding
Result: Negative

Epitope: PPI E
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVELG
Position: 57-69
Source molecule (GenBank): 4557671
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 30600.0

Epitope: PPI E
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVELG
Position: 57-69
Source molecule (GenBank): 4557671
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 29700.0

Epitope: PPI E
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVELG
Position: 57-69
Source molecule (GenBank): 4557671
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 36000.0

Epitope: PPI E
Chemical type: Peptide from protein
Sequence: EAEDLQVGQVELG
Position: 57-69
Source molecule (GenBank): 4557671
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 700.0

Epitope: IA-2 P4
Chemical type: Peptide from protein
Sequence: GAHGDTTFEYQDL
Position: 619-631
Source molecule (GenBank): 4506321
Assay category: MhcBinding
Result: Negative

Epitope: IA-2 P4
Chemical type: Peptide from protein
Sequence: GAHGDTTFEYQDL
Position: 619-631
Source molecule (GenBank): 4506321
Assay category: MhcBinding
Result: Negative

Epitope: IA-2 P4
Chemical type: Peptide from protein
Sequence: GAHGDTTFEYQDL
Position: 619-631
Source molecule (GenBank): 4506321
Assay category: MhcBinding
Result: Negative

Epitope: IA-2 P4
Chemical type: Peptide from protein
Sequence: GAHGDTTFEYQDL
Position: 619-631
Source molecule (GenBank): 4506321
Assay category: MhcBinding
Result: Negative

Epitope: Phogrin P1 E
Chemical type: Peptide from protein
Sequence: QKLSGTGFTWQDD
Position: 87-99
Source molecule (GenBank): 1620664
Assay category: MhcBinding
Result: Negative

Epitope: Phogrin P1 E
Chemical type: Peptide from protein
Sequence: QKLSGTGFTWQDD
Position: 87-99
Source molecule (GenBank): 1620664
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 900.0

Epitope: Phogrin P1 E
Chemical type: Peptide from protein
Sequence: QKLSGTGFTWQDD
Position: 87-99
Source molecule (GenBank): 1620664
Assay category: MhcBinding
Result: Negative

Epitope: Phogrin P1 E
Chemical type: Peptide from protein
Sequence: QKLSGTGFTWQDD
Position: 87-99
Source molecule (GenBank): 1620664
Assay category: MhcBinding
Result: Positive-Low
Quantitative measurement: 23600.0

Epitope: IA-2 P7
Chemical type: Peptide from protein
Sequence: SPAVQPDAALQRL
Position: 326-338
Source molecule (GenBank): 4506321
Assay category: MhcBinding
Result: Negative

Epitope: IA-2 P7
Chemical type: Peptide from protein
Sequence: SPAVQPDAALQRL
Position: 326-338
Source molecule (GenBank): 4506321
Assay category: MhcBinding
Result: Negative

Epitope: IA-2 P7
Chemical type: Peptide from protein
Sequence: SPAVQPDAALQRL
Position: 326-338
Source molecule (GenBank): 4506321
Assay category: MhcBinding
Result: Negative

Epitope: IA-2 P7
Chemical type: Peptide from protein
Sequence: SPAVQPDAALQRL
Position: 326-338
Source molecule (GenBank): 4506321
Assay category: MhcBinding
Result: Negative

Epitope: InsB30-C13 QE
Chemical type: Peptide from protein
Sequence: TRREAEDLQVGQVELG
Position: 54-69
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive
Host:  24-38 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: InsB30-C13 QE
Chemical type: Peptide from protein
Sequence: TRREAEDLQVGQVELG
Position: 54-69
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive
Host:  15-37 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: InsB30-C13 QE
Chemical type: Peptide from protein
Sequence: TRREAEDLQVGQVELG
Position: 54-69
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive
Host: F 11 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: InsB30-C13 QE
Chemical type: Peptide from protein
Sequence: TRREAEDLQVGQVELG
Position: 54-69
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive
Host: F 11 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: InsB30-C13 QE
Chemical type: Peptide from protein
Sequence: TRREAEDLQVGQVELG
Position: 54-69
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive
Host:  15-37 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: InsB30-C13 QE
Chemical type: Peptide from protein
Sequence: TRREAEDLQVGQVELG
Position: 54-69
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive
Host:  24-38 years
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: InsB30-C13 QE
Chemical type: Peptide from protein
Sequence: TRREAEDLQVGQVELG
Position: 54-69
Source molecule (GenBank): NP_000198.1
Assay category: TCell
Result: Positive
Host: F 11 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: InsB30-C13 QE
Chemical type: Peptide from protein
Sequence: TRREAEDLQVGQVELG
Position: 54-69
Source molecule (GenBank): NP_000198.1
Assay category: MhcBinding
Result: Negative

Epitope: InsB30-C13 QE
Chemical type: Peptide from protein
Sequence: TRREAEDLQVGQVELG
Position: 54-69
Source molecule (GenBank): NP_000198.1
Assay category: MhcBinding
Result: Positive-Low

Epitope: InsB30-C13 QE
Chemical type: Peptide from protein
Sequence: TRREAEDLQVGQVELG
Position: 54-69
Source molecule (GenBank): NP_000198.1
Assay category: MhcBinding
Result: Negative

Epitope: InsB30-C13 QE
Chemical type: Peptide from protein
Sequence: TRREAEDLQVGQVELG
Position: 54-69
Source molecule (GenBank): NP_000198.1
Assay category: MhcBinding
Result: Positive-High