Reference: Belén Aparicio; Noelia Casares; Josune Egea; Marta Ruiz; Diana Llopiz; Sheila Maestro; Cristina Olagüe; Gloria González-Aseguinolaza; Cristian Smerdou; Ascensión López-Díaz de Cerio; Susana Inogés; Felipe Prósper; José R Yuste; Francisco Carmona-Torre; Gabriel Reina; Juan J Lasarte; Pablo Sarobe. "Preclinical evaluation of a synthetic peptide vaccine against SARS-CoV-2 inducing multiepitopic and cross-reactive humoral neutralizing and cellular CD4 and CD8 responses." Emerging microbes & infections (2021).

Epitope: SARS-CoV-2 Spike 431-445
Chemical type: Peptide from protein
Sequence: GCVIAWNSNNLDSKV
Position: 431-445
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Positive

Epitope: SARS-CoV-2 Spike 431-445
Chemical type: Peptide from protein
Sequence: GCVIAWNSNNLDSKV
Position: 431-445
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Positive-Low
Host:  20-89 years

Epitope: SARS-CoV-2 Spike 431-445
Chemical type: Peptide from protein
Sequence: GCVIAWNSNNLDSKV
Position: 431-445
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Negative

Epitope: SARS-CoV-2 Spike 431-445
Chemical type: Peptide from protein
Sequence: GCVIAWNSNNLDSKV
Position: 431-445
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Positive

Epitope: SARS-CoV-2 Spike 431-445
Chemical type: Peptide from protein
Sequence: GCVIAWNSNNLDSKV
Position: 431-445
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Negative

Epitope: SARS-CoV-2 Spike 431-445
Chemical type: Peptide from protein
Sequence: GCVIAWNSNNLDSKV
Position: 431-445
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Negative

Epitope: SARS-CoV-2 Spike 456-470
Chemical type: Peptide from protein
Sequence: FRKSNLKPFERDIST
Position: 456-470
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Negative

Epitope: SARS-CoV-2 Spike 456-470
Chemical type: Peptide from protein
Sequence: FRKSNLKPFERDIST
Position: 456-470
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Positive-Low

Epitope: SARS-CoV-2 Spike 456-470
Chemical type: Peptide from protein
Sequence: FRKSNLKPFERDIST
Position: 456-470
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Positive

Epitope: SARS-CoV-2 Spike 456-470
Chemical type: Peptide from protein
Sequence: FRKSNLKPFERDIST
Position: 456-470
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Positive

Epitope: SARS-CoV-2 Spike 456-470
Chemical type: Peptide from protein
Sequence: FRKSNLKPFERDIST
Position: 456-470
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Positive-Low
Host:  20-89 years

Epitope: SARS-CoV-2 Spike 456-470
Chemical type: Peptide from protein
Sequence: FRKSNLKPFERDIST
Position: 456-470
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Negative

Epitope: SARS-CoV-2 Spike 456-470
Chemical type: Peptide from protein
Sequence: FRKSNLKPFERDIST
Position: 456-470
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Positive

Epitope: SARS-CoV-2 Spike 456-470
Chemical type: Peptide from protein
Sequence: FRKSNLKPFERDIST
Position: 456-470
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Positive

Epitope: SARS-CoV-2 Spike 456-470
Chemical type: Peptide from protein
Sequence: FRKSNLKPFERDIST
Position: 456-470
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SARS-CoV-2 Spike 471-485
Chemical type: Peptide from protein
Sequence: EIYQAGSTPCNGVEG
Position: 471-485
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Negative

Epitope: SARS-CoV-2 Spike 471-485
Chemical type: Peptide from protein
Sequence: EIYQAGSTPCNGVEG
Position: 471-485
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Negative

Epitope: SARS-CoV-2 Spike 471-485
Chemical type: Peptide from protein
Sequence: EIYQAGSTPCNGVEG
Position: 471-485
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Negative

Epitope: SARS-CoV-2 Spike 471-485
Chemical type: Peptide from protein
Sequence: EIYQAGSTPCNGVEG
Position: 471-485
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Negative

Epitope: SARS-CoV-2 Spike 471-485
Chemical type: Peptide from protein
Sequence: EIYQAGSTPCNGVEG
Position: 471-485
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Negative

Epitope: SARS-CoV-2 Spike 471-485
Chemical type: Peptide from protein
Sequence: EIYQAGSTPCNGVEG
Position: 471-485
Source molecule (GenBank): YP_009724390.1
Assay category: BCell
Result: Positive-Low
Host:  20-89 years

Epitope: SARS-CoV-2 Spike 1-20
Chemical type: Peptide from protein
Sequence: MFVFLVLLPLVSSQCVNLTT
Position: 1-20
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive-Low
Host:  8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SARS-CoV-2 Spike 1-20
Chemical type: Peptide from protein
Sequence: MFVFLVLLPLVSSQCVNLTT
Position: 1-20
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SARS-CoV-2 Spike 211-230
Chemical type: Peptide from protein
Sequence: NLVRDLPQGFSALEPLVDLP
Position: 211-230
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Negative
Host:  8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SARS-CoV-2 Spike 211-230
Chemical type: Peptide from protein
Sequence: NLVRDLPQGFSALEPLVDLP
Position: 211-230
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive-Low
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SARS-CoV-2 Spike 251-270
Chemical type: Peptide from protein
Sequence: PGDSSSGWTAGAAAYYVGYL
Position: 251-270
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Negative
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SARS-CoV-2 Spike 251-270
Chemical type: Peptide from protein
Sequence: PGDSSSGWTAGAAAYYVGYL
Position: 251-270
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Negative
Host:  8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SARS-CoV-2 Spike 301-320
Chemical type: Peptide from protein
Sequence: CTLKSFTVEKGIYQTSNFRV
Position: 301-320
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive
Host:  8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SARS-CoV-2 Spike 301-320
Chemical type: Peptide from protein
Sequence: CTLKSFTVEKGIYQTSNFRV
Position: 301-320
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive-Low
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SARS-CoV-2 Spike 331-350
Chemical type: Peptide from protein
Sequence: NITNLCPFGEVFNATRFASV
Position: 331-350
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive
Host:  8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SARS-CoV-2 Spike 331-350
Chemical type: Peptide from protein
Sequence: NITNLCPFGEVFNATRFASV
Position: 331-350
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SARS-CoV-2 Spike 361-380
Chemical type: Peptide from protein
Sequence: CVADYSVLYNSASFSTFKCY
Position: 361-380
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive-Low
Host:  8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SARS-CoV-2 Spike 361-380
Chemical type: Peptide from protein
Sequence: CVADYSVLYNSASFSTFKCY
Position: 361-380
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Negative
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SARS-CoV-2 Spike 441-460
Chemical type: Peptide from protein
Sequence: LDSKVGGNYNYLYRLFRKSN
Position: 441-460
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Negative
Host:  8 weeks
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: SARS-CoV-2 Spike 441-460
Chemical type: Peptide from protein
Sequence: LDSKVGGNYNYLYRLFRKSN
Position: 441-460
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Negative
Host:  8 weeks
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo