LiteFold/IEDB huggingface dataset:
Reference: Justin D Walter; Rachel A Werther; Maria S Polozova; Julie Pohlman; John F Healey; Shannon L Meeks; Pete Lollar; P Clint Spiegel. "Characterization and solution structure of the factor VIII C2 domain in a ternary complex with classical and non-classical inhibitor antibodies." The Journal of biological chemistry (2013).

Epitope: Epitope residue of mAb 3E6 on Factor VIII C2 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: K2202
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.2
Host:  9-12 weeks

Epitope: Epitope residue of mAb 3E6 on Factor VIII C2 domain
Chemical type: Discontinuous protein residues
Discontinuous residues: K2202
Source molecule (GenBank): P00451.1
Assay category: BCell
Result: Positive
Host:  9-12 weeks
Reference: Paul M Arnaboldi; Rudra Seedarnee; Mariya Sambir; Steven M Callister; Josephine A Imparato; Raymond J Dattwyler. "Outer surface protein C peptide derived from Borrelia burgdorferi sensu stricto as a target for serodiagnosis of early lyme disease." Clinical and vaccine immunology :  CVI. (2013).

Epitope: OpsC18
Chemical type: Peptide from protein
Sequence: TLLAGAYTISKLITQ
Position: 86-100
Source molecule (GenBank): AAB86554.1
Assay category: BCell
Result: Positive

Epitope: OpsC18
Chemical type: Peptide from protein
Sequence: TLLAGAYTISKLITQ
Position: 86-100
Source molecule (GenBank): AAB86554.1
Assay category: BCell
Result: Positive

Epitope: OpsC35
Chemical type: Peptide from protein
Sequence: VENLAKAAKEMLANS
Position: 171-185
Source molecule (GenBank): AAB86554.1
Assay category: BCell
Result: Negative
Reference: Kannan Tharakaraman; Luke N Robinson; Andrew Hatas; Yi-Ling Chen; Liu Siyue; S Raguram; V Sasisekharan; Gerald N Wogan; Ram Sasisekharan. "Redesign of a cross-reactive antibody to dengue virus with broad-spectrum activity and increased in vivo potency." Proceedings of the National Academy of Sciences of the United States of America (2013).

Epitope: Epitope of 4E11 on DENV-4 DIII
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, T361, N362, S363, V364, N366, L387, T388, L389, H390
Source molecule (GenBank): ABD17411.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of 4E11 on DENV-4 DIII
Chemical type: Discontinuous protein residues
Discontinuous residues: K305, F306, S307, I308, D309, K310, E311, M312, K323, K325, E327, T361, N362, S363, V364, N366, L387, T388, L389, H390
Source molecule (GenBank): ABD17411.1
Assay category: BCell
Result: Positive-Low
Quantitative measurement: 40793.0
Reference: Marine L B Hillaire; Stella E Vogelzang-van Trierum; Joost H C M Kreijtz; Gerrie de Mutsert; Ron A M Fouchier; Albert D M E Osterhaus; Guus F Rimmelzwaan. "Human T-cells directed to seasonal influenza A virus cross-react with 2009 pandemic influenza A (H1N1) and swine-origin triple-reassortant H3N2 influenza viruses." The Journal of general virology (2013).

Epitope: AIMEKNIIL
Chemical type: Peptide from protein
Sequence: AIMEKNIIL
Position: 122-130
Source molecule (GenBank): AAG10764.1
Assay category: TCell
Result: Negative
Host:  30-48 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: AIMEKNIIL
Chemical type: Peptide from protein
Sequence: AIMEKNIIL
Position: 122-130
Source molecule (GenBank): AAG10764.1
Assay category: TCell
Result: Positive
Host:  30-48 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: ELKSRYWAI
Chemical type: Peptide from protein
Sequence: ELKSRYWAI
Position: 380-388
Source molecule (GenBank): ADG96394.1
Assay category: TCell
Result: Positive
Host:  30-48 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: ELKSRYWAI
Chemical type: Peptide from protein
Sequence: ELKSRYWAI
Position: 380-388
Source molecule (GenBank): ADG96394.1
Assay category: TCell
Result: Negative
Host:  30-48 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ELKSRYWAI
Chemical type: Peptide from protein
Sequence: ELKSRYWAI
Position: 380-388
Source molecule (GenBank): ADG96394.1
Assay category: TCell
Result: Positive
Host:  30-48 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RKRSGAAGAAVK
Chemical type: Peptide from protein
Sequence: RKSGAAGAAVK
Position: 174-184
Source molecule (GenBank): AGI52867.1
Assay category: TCell
Result: Negative
Host:  30-48 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: RKRSGAAGAAVK
Chemical type: Peptide from protein
Sequence: RKSGAAGAAVK
Position: 174-184
Source molecule (GenBank): AGI52867.1
Assay category: TCell
Result: Negative
Host:  30-48 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated
Reference: L E Pedersen; M Harndahl; M Nielsen; J R Patch; G Jungersen; S Buus; W T Golde. "Identification of peptides from foot-and-mouth disease virus structural proteins bound by class I swine leukocyte antigen (SLA) alleles, SLA-1*0401 and SLA-2*0401." Animal genetics (2013).

Epitope: ASYQFQLPY
Chemical type: Peptide from protein
Sequence: ASYQFQLPY
Position: 208-216
Source molecule (GenBank): Q9KRL2
Assay category: MhcBinding
Result: Positive-High
Quantitative measurement: 2.0
Reference: Javier Martínez-Botas; Inmaculada Cerecedo; Javier Zamora; Cristina Vlaicu; Maria Carmen Dieguez; Diego Gómez-Coronado; Verónica de Dios; Soledad Terrados; Belén de la Hoz. "Mapping of the IgE and IgG4 sequential epitopes of ovomucoid with a peptide microarray immunoassay." International archives of allergy and immunology (2013).

Epitope: P13
Chemical type: Peptide from protein
Sequence: YTNDCLLCAYSIEFGTNISK
Position: 61-80
Source molecule (GenBank): P01005.1
Assay category: BCell
Result: Positive
Host:  3-14 years

Epitope: P16
Chemical type: Peptide from protein
Sequence: YSIEFGTNISKEHDGECKET
Position: 70-89
Source molecule (GenBank): P01005.1
Assay category: BCell
Result: Positive
Host:  3-14 years

Epitope: P21
Chemical type: Peptide from protein
Sequence: ECKETVPMNCSSYANTTSED
Position: 85-104
Source molecule (GenBank): P01005.1
Assay category: BCell
Result: Positive
Host:  3-14 years

Epitope: P26
Chemical type: Peptide from protein
Sequence: TTSEDGKVMVLCNRAFNPVC
Position: 100-119
Source molecule (GenBank): P01005.1
Assay category: BCell
Result: Positive
Host:  3-14 years

Epitope: P42
Chemical type: Peptide from protein
Sequence: DGGCRKELAAVSVDCSEYPK
Position: 148-167
Source molecule (GenBank): P01005.1
Assay category: BCell
Result: Positive
Host:  3-14 years

Epitope: P67
Chemical type: Peptide from protein
Sequence: VLVCNKDLRPICGTD
Position: 43-57
Source molecule (GenBank): P01005.1
Assay category: BCell
Result: Negative
Host:  child

Epitope: P73
Chemical type: Peptide from protein
Sequence: YTNDCLLCAYSIEFG
Position: 61-75
Source molecule (GenBank): P01005.1
Assay category: BCell
Result: Negative
Host:  child

Epitope: P76
Chemical type: Peptide from protein
Sequence: YSIEFGTNISKEHDG
Position: 70-84
Source molecule (GenBank): P01005.1
Assay category: BCell
Result: Negative
Host:  child

Epitope: P79
Chemical type: Peptide from protein
Sequence: SKEHDGECKETVPMN
Position: 79-93
Source molecule (GenBank): P01005.1
Assay category: BCell
Result: Negative
Host:  child

Epitope: P85
Chemical type: Peptide from protein
Sequence: YANTTSEDGKVMVLC
Position: 97-111
Source molecule (GenBank): P01005.1
Assay category: BCell
Result: Negative
Host:  child

Epitope: P89
Chemical type: Peptide from protein
Sequence: VLCNRAFNPVCGTDG
Position: 109-123
Source molecule (GenBank): P01005.1
Assay category: BCell
Result: Negative
Host:  child

Epitope: P91
Chemical type: Peptide from protein
Sequence: FNPVCGTDGVTYDNE
Position: 115-129
Source molecule (GenBank): P01005.1
Assay category: BCell
Result: Negative
Host:  child

Epitope: P97
Chemical type: Peptide from protein
Sequence: CAHKVEQGASVDKRH
Position: 133-147
Source molecule (GenBank): P01005.1
Assay category: BCell
Result: Negative
Host:  child

Epitope: P98
Chemical type: Peptide from protein
Sequence: KVEQGASVDKRHDGG
Position: 136-150
Source molecule (GenBank): P01005.1
Assay category: BCell
Result: Negative
Host:  child

Epitope: P108
Chemical type: Peptide from protein
Sequence: PKPDCTAEDRPLCGS
Position: 166-180
Source molecule (GenBank): P01005.1
Assay category: BCell
Result: Negative
Host:  child
Reference: Johan Verhagen; Bronwen R Burton; Graham J Britton; Ella R Shepard; Stephen M Anderton; David C Wraith. "Modification of the FoxP3 transcription factor principally affects inducible T regulatory cells in a model of experimental autoimmune encephalomyelitis." PloS one (2013).

Epitope: MBP Ac1-9
Chemical type: Peptide from protein
Sequence: ASQKRPSQR
Position: 2-10
Source molecule (GenBank): ABI54132.1
Assay category: TCell
Result: Positive
Host:  14-15 weeks

Epitope: MBP Ac1-9
Chemical type: Peptide from protein
Sequence: ASQKRPSQR
Position: 2-10
Source molecule (GenBank): ABI54132.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo
Reference: Nicoletta Sorvillo; Simon D van Haren; Paul H Kaijen; Anja ten Brinke; Rob Fijnheer; Alexander B Meijer; Jan Voorberg. "Preferential HLA-DRB1*11-dependent presentation of CUB2-derived peptides by ADAMTS13-pulsed dendritic cells." Blood (2013).

Epitope: ADAMTS13 (266-280)
Chemical type: Peptide from protein
Sequence: SRRQLLSLLSAGRAR
Position: 266-280
Source molecule (GenBank): AAL11095.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 57 437

Epitope: ADAMTS13 (1355-1368)
Chemical type: Peptide from protein
Sequence: ASYILIRDTHSLRT
Position: 1355-1368
Source molecule (GenBank): AAL11095.1
Assay category: MhcLigandElution
Result: Positive

Epitope: ADAMTS13 (1335-1349)
Chemical type: Peptide from protein
Sequence: ARIAIHALATNMGAG
Position: 1335-1349
Source molecule (GenBank): AAL11095.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 63 57

Epitope: ADAMTS13 (1194-1209)
Chemical type: Peptide from protein
Sequence: RQHLEPTGTIDMRGPG
Position: 1194-1209
Source molecule (GenBank): AAL11095.1
Assay category: MhcLigandElution
Result: Positive
MHC allele types: 413 436
Reference: Lakshmi A Mundkur; Meenakshi Varma; Hemapriya Shivanandan; Dhanush Krishna; Kiran Kumar; Xinjie Lu; Vijay V Kakkar. "Activation of inflammatory cells and cytokines by peptide epitopes in vitro: a simple in-vitro screening assay for prioritizing them for in-vivo studies." Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2013).

Epitope: HSP60 peptide
Chemical type: Peptide from protein
Sequence: AELKKQSKPVT
Position: 153-163
Source molecule (GenBank): AAA36022.1
Assay category: TCell
Result: Positive
Host:  5-6 weeks

Epitope: HSP60 peptide
Chemical type: Peptide from protein
Sequence: AELKKQSKPVT
Position: 153-163
Source molecule (GenBank): AAA36022.1
Assay category: TCell
Result: Positive
Host:  25-40 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HSP60 peptide
Chemical type: Peptide from protein
Sequence: AELKKQSKPVT
Position: 153-163
Source molecule (GenBank): AAA36022.1
Assay category: TCell
Result: Positive
Host:  25-40 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HSP60 peptide
Chemical type: Peptide from protein
Sequence: AELKKQSKPVT
Position: 153-163
Source molecule (GenBank): AAA36022.1
Assay category: TCell
Result: Positive
Host:  25-40 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HSP60 peptide
Chemical type: Peptide from protein
Sequence: AELKKQSKPVT
Position: 153-163
Source molecule (GenBank): AAA36022.1
Assay category: TCell
Result: Positive
Host:  25-40 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: HSP60 peptide
Chemical type: Peptide from protein
Sequence: AELKKQSKPVT
Position: 153-163
Source molecule (GenBank): AAA36022.1
Assay category: TCell
Result: Positive
Host:  25-40 years
Cell type: T cell
Tissue: blood
Culture conditions: Direct Ex Vivo
Reference: Aleeza J Roth; Joshua D Ooi; Jacob J Hess; Mirjan M van Timmeren; Elisabeth A Berg; Caroline E Poulton; JulieAnne McGregor; Madelyn Burkart; Susan L Hogan; Yichun Hu; Witold Winnik; Patrick H Nachman; Coen A Stegeman; John Niles; Peter Heeringa; A Richard Kitching; Stephen Holdsworth; J Charles Jennette; Gloria A Preston; Ronald J Falk. "Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis." The Journal of clinical investigation (2013).

Epitope: MPO 198–219
Chemical type: Peptide from protein
Sequence: WLPAEYEDGFSLPYG
Position: 198-212
Source molecule (GenBank): P05164.1
Assay category: BCell
Result: Positive
Host:  19-83 years

Epitope: MPO 198–219
Chemical type: Peptide from protein
Sequence: WLPAEYEDGFSLPYG
Position: 198-212
Source molecule (GenBank): P05164.1
Assay category: BCell
Result: Negative
Host:  20-53 years

Epitope: MPO 460–473
Chemical type: Peptide from protein
Sequence: RDYLPLVLGPTAMR
Position: 460-473
Source molecule (GenBank): P05164.1
Assay category: BCell
Result: Positive
Host:  20-53 years

Epitope: MPO 460–473
Chemical type: Peptide from protein
Sequence: RDYLPLVLGPTAMR
Position: 460-473
Source molecule (GenBank): P05164.1
Assay category: BCell
Result: Positive
Host:  19-83 years
Reference: I-Ting Chow; Eddie A James; Theresa J Gates; Venus Tan; Antonis K Moustakas; George K Papadopoulos; William W Kwok. "Differential binding of pyruvate dehydrogenase complex-E2 epitopes by DRB1*08:01 and DRB1*11:01 Is predicted by their structural motifs and correlates with disease risk." Journal of immunology (Baltimore, Md. : 1950) (2013).

Epitope: KLMRKLKREITFH
Chemical type: Peptide, no natural source
Sequence: KLMRKLKREITFH
Assay category: MhcBinding
Result: Positive

Epitope: KLYRKVKREITFH
Chemical type: Peptide, no natural source
Sequence: KLYRKVKREITFH
Assay category: MhcBinding
Result: Positive-Low

Epitope: KLYRKNKREITFH
Chemical type: Peptide, no natural source
Sequence: KLYRKNKREITFH
Assay category: MhcBinding
Result: Negative

Epitope: KLYRKLKQEITFH
Chemical type: Peptide, no natural source
Sequence: KLYRKLKQEITFH
Assay category: MhcBinding
Result: Negative

Epitope: KLYRKLKTEITFH
Chemical type: Peptide, no natural source
Sequence: KLYRKLKTEITFH
Assay category: MhcBinding
Result: Negative

Epitope: KLYRKLKREIPFH
Chemical type: Peptide, no natural source
Sequence: KLYRKLKREIPFH
Assay category: MhcBinding
Result: Positive

Epitope: KLYRKLKREIRFH
Chemical type: Peptide, no natural source
Sequence: KLYRKLKREIRFH
Assay category: MhcBinding
Result: Positive

Epitope: H1HA 416-432
Chemical type: Peptide from protein
Sequence: LERRMENLNKKVDDGFL
Position: 416-432
Source molecule (GenBank): ACD37430.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: E2 603-617
Chemical type: Peptide from protein
Sequence: EKGFDVASMMSVTLS
Position: 603-617
Source molecule (GenBank): EAW67174.1
Assay category: MhcBinding
Result: Negative

Epitope: E2 603-617
Chemical type: Peptide from protein
Sequence: EKGFDVASMMSVTLS
Position: 603-617
Source molecule (GenBank): EAW67174.1
Assay category: MhcBinding
Result: Negative
Reference: Alexander W Tarr; Pierre Lafaye; Luke Meredith; Laurence Damier-Piolle; Richard A Urbanowicz; Annalisa Meola; Jean-Luc Jestin; Richard J P Brown; Jane A McKeating; Felix A Rey; Jonathan K Ball; Thomas Krey. "An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission." Hepatology (Baltimore, Md.) (2013).

Epitope: Epitope of nanobody D03 on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: N415, G523, T526
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody D03 on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: N415, G523, T526
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Negative
Host: M

Epitope: Epitope of nanobody D03 on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: N415, G523, T526
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody D03 on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: N415, G523, T526
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody D03 on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: N415, G523, T526
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody D03 on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: N415, G523, T526
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody D03 on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: N415, G523, T526
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive
Host: M

Epitope: Epitope of nanobody D03 on HCV E2
Chemical type: Discontinuous protein residues
Discontinuous residues: N415, G523, T526
Source molecule (GenBank): AAB67036.1
Assay category: BCell
Result: Positive
Host: M
Reference: Atsushi Otsuka; Saeko Nakajima; Masato Kubo; Gyohei Egawa; Tetsuya Honda; Akihiko Kitoh; Takashi Nomura; Sho Hanakawa; Catharina Sagita Moniaga; Bongju Kim; Satoshi Matsuoka; Takeshi Watanabe; Yoshiki Miyachi; Kenji Kabashima. "Basophils are required for the induction of Th2 immunity to haptens and peptide antigens." Nature communications (2013).

Epitope: oxazolone
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive-Low
Host: F 8-10 weeks

Epitope: oxazolone
Chemical type: Other Non-Sequence
Assay category: BCell
Result: Positive
Host: F 8-10 weeks

Epitope: oxazolone
Chemical type: Other Non-Sequence
Assay category: TCell
Result: Positive
Host: F 8-10 weeks
Reference: S B Cho; Z Zheng; K J Ahn; M J Choi; S Cho; D-Y Kim; H S Lee; D Bang. "Serum IgA reactivity against GroEL of Streptococcus sanguinis and human heterogeneous nuclear ribonucleoprotein A2/B1 in patients with Behçet disease." The British journal of dermatology (2013).

Epitope: E2 hnRNP A2/B1
Chemical type: Peptide from protein
Sequence: PLERKKREKEQFRKLFIGGL
Position: 9-28
Source molecule (GenBank): P22626.2
Assay category: BCell
Result: Positive
Host:  40.6 +/- 11.4 years

Epitope: E2 hnRNP A2/B1
Chemical type: Peptide from protein
Sequence: PLERKKREKEQFRKLFIGGL
Position: 9-28
Source molecule (GenBank): P22626.2
Assay category: BCell
Result: Negative
Reference: Mahdi Habibi Anbouhi; Mohsen Abolhassani; Saeid Bouzari; Hossein Khanahmad; Mohammad Reza Aghasadeghi; Armin Madadkar-Sobhani; Amir Amanzadeh; Mahdi Behdani; Mohammad Ali Shokrgozar. "Immunological evaluation of predicted linear B-cell epitopes of human CD20 antigen." Biotechnology and applied biochemistry (2012).

Epitope: P3
Chemical type: Peptide from protein
Sequence: AHTPYINIYNCEPANP
Position: 157-172
Source molecule (GenBank): P11836.1
Assay category: BCell
Result: Positive-Low
Host: F 5 weeks

Epitope: P3
Chemical type: Peptide from protein
Sequence: AHTPYINIYNCEPANP
Position: 157-172
Source molecule (GenBank): P11836.1
Assay category: BCell
Result: Positive
Host: F 5 weeks

Epitope: P3
Chemical type: Peptide from protein
Sequence: AHTPYINIYNCEPANP
Position: 157-172
Source molecule (GenBank): P11836.1
Assay category: BCell
Result: Positive
Host: F 5 weeks

Epitope: P3
Chemical type: Peptide from protein
Sequence: AHTPYINIYNCEPANP
Position: 157-172
Source molecule (GenBank): P11836.1
Assay category: BCell
Result: Positive-High
Host: F 5 weeks
Reference: Susanne B Rasmussen; Mikkel N Harndahl; Anette Stryhn; Søren Buus; Mogens H Claesson. "Peptide pool immunization and CD8+ T cell reactivity." Immunology letters (2013).

Epitope: Peptide 4
Chemical type: Peptide from protein
Sequence: MSYIFGASL
Position: 135-143
Source molecule (GenBank): WP_001696657.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: T cell CD4-
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: Peptide 4
Chemical type: Peptide from protein
Sequence: MSYIFGASL
Position: 135-143
Source molecule (GenBank): WP_001696657.1
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 600.0
Reference: Hans Hilpert; Wolfgang Guba; Thomas J Woltering; Wolfgang Wostl; Emmanuel Pinard; Harald Mauser; Alexander V Mayweg; Mark Rogers-Evans; Roland Humm; Daniela Krummenacher; Thorsten Muser; Christian Schnider; Helmut Jacobsen; Laurence Ozmen; Alessandra Bergadano; David W Banner; Remo Hochstrasser; Andreas Kuglstatter; Pascale David-Pierson; Holger Fischer; Alessandra Polara; Robert Narquizian. "β-Secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease." Journal of medicinal chemistry (2013).

Epitope: Epitope of VHH XA4813 on BACE-2
Chemical type: Discontinuous protein residues
Discontinuous residues: T137, R139, K141, E160, L174, V175, N176, A202, S209, S210, E212, T220, Q221, N223
Source molecule (GenBank): Q9Y5Z0.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.1
Reference: Colin Correnti; Vera Richardson; Allyson K Sia; Ashok D Bandaranayake; Mario Ruiz; Yohan Suryo Rahmanto; Žaklina Kovačević; Matthew C Clifton; Margaret A Holmes; Brett K Kaiser; Jonathan Barasch; Kenneth N Raymond; Des R Richardson; Roland K Strong. "Siderocalin/Lcn2/NGAL/24p3 does not drive apoptosis through gentisic acid mediated iron withdrawal in hematopoietic cell lines." PloS one (2012).

Epitope: Epitope of MAB1857 on murine siderocalin (Scn)
Chemical type: Discontinuous protein residues
Discontinuous residues: P29, A30, P31, S32, L33, L34, T35, S109, R110, Q113, Q126, S127, N129, R146, K147, T148, Q153
Source molecule (GenBank): P11672.1
Assay category: BCell
Result: Positive
Quantitative measurement: 2.8
Reference: C Gelber; L Gemmell; D McAteer; M Homola; P Swain; A Liu; K J Wilson; M Gefter. "Down-regulation of poison ivy/oak-induced contact sensitivity by treatment with a class II MHC binding peptide:hapten conjugate." Journal of immunology (Baltimore, Md. : 1950) (1997).

Epitope: I-Eα 54-66, K60
Chemical type: Peptide, no natural source
Sequence: FEAQGAKANIAVD
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: I-Eα 54-66, K60
Chemical type: Peptide, no natural source
Sequence: FEAQGAKANIAVD
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 5600.0

Epitope: A6:7
Chemical type: Peptide, no natural source
Sequence: YDDNGAKQNAAER
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0

Epitope: A6:7
Chemical type: Peptide, no natural source
Sequence: YDDNGAKQNAAER
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 4700.0

Epitope: E5:10
Chemical type: Peptide, no natural source
Sequence: AAIAAAAAAKRAA
Assay category: MhcBinding
Result: Positive
Quantitative measurement: 150.0

Epitope: E5:10
Chemical type: Peptide, no natural source
Sequence: AAIAAAAAAKRAA
Assay category: MhcBinding
Result: Negative
Quantitative measurement: 100000.0
Reference: Cheng-bo Fang; De-xi Zhou; Shu-xiang Zhan; Yong He; Zhen Lin; Cheng Huang; Jun Li. "Amelioration of experimental autoimmune uveitis by leflunomide in Lewis rats." PloS one (2013).

Epitope: IRBP (1169-1191)
Chemical type: Peptide from protein
Sequence: PTARSVGAADGSSWEGVGVVPDV
Position: 1191-1213
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks

Epitope: IRBP (1169-1191)
Chemical type: Peptide from protein
Sequence: PTARSVGAADGSSWEGVGVVPDV
Position: 1191-1213
Source molecule (GenBank): NP_776589.1
Assay category: TCell
Result: Positive
Host: F 6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo