Reference: Rúbens Prince Dos Santos Alves; Julia Timis; Robyn Miller; Kristen Valentine; Paolla Beatriz Almeida Pinto; Andrew Gonzalez; Jose Angel Regla-Nava; Erin Maule; Michael N Nguyen; Norazizah Shafee; Sara Landeras-Bueno; Eduardo Olmedillas; Brett Laffey; Katarzyna Dobaczewska; Zbigniew Mikulski; Sara McArdle; Sarah R Leist; Kenneth Kim; Ralph S Baric; Erica Ollmann Saphire; Annie Elong Ngono; Sujan Shresta. "Human coronavirus OC43-elicited CD4<sup>+</sup> T cells protect against SARS-CoV-2 in HLA transgenic mice." Nature communications (2024).

Epitope: S 38-47
Chemical type: Peptide from protein
Sequence: YPDKVFRSSV
Position: 38-47
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 38-47
Chemical type: Peptide from protein
Sequence: YPDKVFRSSV
Position: 38-47
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 216-223
Chemical type: Peptide from protein
Sequence: LPQGFSAL
Position: 216-223
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 216-223
Chemical type: Peptide from protein
Sequence: LPQGFSAL
Position: 216-223
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 216-226
Chemical type: Peptide from protein
Sequence: LPQGFSALEPL
Position: 216-226
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 216-226
Chemical type: Peptide from protein
Sequence: LPQGFSALEPL
Position: 216-226
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 462-472
Chemical type: Peptide from protein
Sequence: KPFERDISTEI
Position: 462-472
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 462-472
Chemical type: Peptide from protein
Sequence: KPFERDISTEI
Position: 462-472
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 506-515
Chemical type: Peptide from protein
Sequence: QPYRVVVLSF
Position: 506-515
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 506-515
Chemical type: Peptide from protein
Sequence: QPYRVVVLSF
Position: 506-515
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 811-818
Chemical type: Peptide from protein
Sequence: KPSKRSFI
Position: 811-818
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive-Low
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 811-818
Chemical type: Peptide from protein
Sequence: KPSKRSFI
Position: 811-818
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 1261-1270
Chemical type: Peptide from protein
Sequence: SEPVLKGVKL
Position: 1261-1270
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 1261-1270
Chemical type: Peptide from protein
Sequence: SEPVLKGVKL
Position: 1261-1270
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M 122-129
Chemical type: Peptide from protein
Sequence: VPLHGTIL
Position: 122-129
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M 122-129
Chemical type: Peptide from protein
Sequence: VPLHGTIL
Position: 122-129
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M 122-129
Chemical type: Peptide from protein
Sequence: VPLHGTIL
Position: 122-129
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: M 122-129
Chemical type: Peptide from protein
Sequence: VPLHGTIL
Position: 122-129
Source molecule (GenBank): P0DTC5.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: N 41-50
Chemical type: Peptide from protein
Sequence: RPQGLPNNTA
Position: 41-50
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Negative
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: N 41-50
Chemical type: Peptide from protein
Sequence: RPQGLPNNTA
Position: 41-50
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: lymphocyte
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: S 1044-1058
Chemical type: Peptide from protein
Sequence: GKGYHLMSFPQSAPH
Position: 1044-1058
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 1044-1058
Chemical type: Peptide from protein
Sequence: GKGYHLMSFPQSAPH
Position: 1044-1058
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 1044-1058
Chemical type: Peptide from protein
Sequence: GKGYHLMSFPQSAPH
Position: 1044-1058
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: lung
Culture conditions: Direct Ex Vivo

Epitope: S 1044-1058
Chemical type: Peptide from protein
Sequence: GKGYHLMSFPQSAPH
Position: 1044-1058
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 1044-1058
Chemical type: Peptide from protein
Sequence: GKGYHLMSFPQSAPH
Position: 1044-1058
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: S 1044-1058
Chemical type: Peptide from protein
Sequence: GKGYHLMSFPQSAPH
Position: 1044-1058
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: ORF1ab 1017-1025
Chemical type: Peptide from protein
Sequence: TPVVQTIEV
Position: 1017-1025
Source molecule (GenBank): P0DTC1.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: ORF1ab 1017-1025
Chemical type: Peptide from protein
Sequence: TPVVQTIEV
Position: 1017-1025
Source molecule (GenBank): P0DTC1.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: ORF1ab 7048-7056
Chemical type: Peptide from protein
Sequence: FPLKLRGTA
Position: 7048-7056
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: ORF1ab 7048-7056
Chemical type: Peptide from protein
Sequence: FPLKLRGTA
Position: 7048-7056
Source molecule (GenBank): P0DTD1.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: N 216-230
Chemical type: Peptide from protein
Sequence: DAALALLLLDRLNQL
Position: 216-230
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: N 216-230
Chemical type: Peptide from protein
Sequence: DAALALLLLDRLNQL
Position: 216-230
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: N 261-275
Chemical type: Peptide from protein
Sequence: KRTATKAYNVTQAFG
Position: 261-275
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: N 261-275
Chemical type: Peptide from protein
Sequence: KRTATKAYNVTQAFG
Position: 261-275
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: N 351-365
Chemical type: Peptide from protein
Sequence: ILLNKHIDAYKTFPP
Position: 351-365
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: N 351-365
Chemical type: Peptide from protein
Sequence: ILLNKHIDAYKTFPP
Position: 351-365
Source molecule (GenBank): P0DTC9.1
Assay category: TCell
Result: Positive
Cell type: T cell CD4+
Tissue: spleen
Culture conditions: Direct Ex Vivo