Reference: Joel Sop; Caroline C Traut; Arbor G Dykema; Joanne H Hunt; Tyler P Beckey; Christie R Basseth; Annukka A R Antar; Oliver Laeyendecker; Kellie N Smith; Joel N Blankson. "Bivalent mRNA COVID vaccines elicit predominantly cross-reactive CD4<sup>+</sup> T cell clonotypes." Cell reports. Medicine (2024).

Epitope: TQLPPAYTNSFTRGVYY
Chemical type: Peptide from protein
Sequence: TQLPPAYTNSFTRGVYY
Position: 22-38
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PLVDLPIGINITRFQTL
Chemical type: Peptide from protein
Sequence: PLVDLPIGINITRFQTL
Position: 225-241
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: RSYLTPGDSSSGWTAGA
Chemical type: Peptide from protein
Sequence: RSYLTPGDSSSGWTAGA
Position: 246-262
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: PFGEVFNATRFASVYAW
Chemical type: Peptide from protein
Sequence: PFGEVFNATRFASVYAW
Position: 337-353
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: DFTGCVIAWNSNNLDSK
Chemical type: Peptide from protein
Sequence: DFTGCVIAWNSNNLDSK
Position: 428-444
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: AWNSNNLDSKVGGNYNY
Chemical type: Peptide from protein
Sequence: AWNSNNLDSKVGGNYNY
Position: 435-451
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: DSKVGGNYNYLYRLFRK
Chemical type: Peptide from protein
Sequence: DSKVGGNYNYLYRLFRK
Position: 442-458
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: VTTEILPVSMTKTSVDC
Chemical type: Peptide from protein
Sequence: VTTEILPVSMTKTSVDC
Position: 722-738
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: GSFCTQLNRALTGIAVE
Chemical type: Peptide from protein
Sequence: GSFCTQLNRALTGIAVE
Position: 757-773
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: NRALTGIAVEQDKNTQE
Chemical type: Peptide from protein
Sequence: NRALTGIAVEQDKNTQE
Position: 764-780
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: LGDIAARDLICAQKFNG
Chemical type: Peptide from protein
Sequence: LGDIAARDLICAQKFNG
Position: 841-857
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: THWFVTQRNFYEPQIIT
Chemical type: Peptide from protein
Sequence: THWFVTQRNFYEPQIIT
Position: 1100-1116
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: SGINASVVNIQKEIDRL
Chemical type: Peptide from protein
Sequence: SGINASVVNIQKEIDRL
Position: 1170-1186
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Positive
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: IDLQELGKYEQYIKWPW
Chemical type: Peptide from protein
Sequence: IDLQELGKYEQYIKWPW
Position: 1198-1214
Source molecule (GenBank): P0DTC2.1
Assay category: TCell
Result: Negative
Cell type: PBMC
Tissue: blood
Culture conditions: Direct Ex Vivo