Reference: Kwok-Ho Lam; Jacqueline M Tremblay; Kay Perry; Konstantin Ichtchenko; Charles B Shoemaker; Rongsheng Jin. "Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies." PLoS pathogens (2022).

Epitope: Epitope of VHH JPU-C10 on BoNT/A LC
Chemical type: Discontinuous protein residues
Discontinuous residues: P63, E64, A65, K66, Q67, V68, P69, V70, P239, V242, Y251, M253, S254, L256, E257, S259, E262, Y366, N368, F369, D370, L422, E424, F425, L428, L429
Source molecule (GenBank): Q7B8V4
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH JPU-C10 on BoNT/A LC
Chemical type: Discontinuous protein residues
Discontinuous residues: P63, E64, A65, K66, Q67, V68, P69, V70, P239, V242, Y251, M253, S254, L256, E257, S259, E262, Y366, N368, F369, D370, L422, E424, F425, L428, L429
Source molecule (GenBank): Q7B8V4
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH JPU-C10 on BoNT/A LC
Chemical type: Discontinuous protein residues
Discontinuous residues: P63, E64, A65, K66, Q67, V68, P69, V70, P239, V242, Y251, M253, S254, L256, E257, S259, E262, Y366, N368, F369, D370, L422, E424, F425, L428, L429
Source molecule (GenBank): Q7B8V4
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH JPU-C10 on BoNT/A LC
Chemical type: Discontinuous protein residues
Discontinuous residues: P63, E64, A65, K66, Q67, V68, P69, V70, P239, V242, Y251, M253, S254, L256, E257, S259, E262, Y366, N368, F369, D370, L422, E424, F425, L428, L429
Source molecule (GenBank): Q7B8V4
Assay category: BCell
Result: Positive
Quantitative measurement: 2.78

Epitope: Epitope of VHH JPU-C10 on BoNT/A LC
Chemical type: Discontinuous protein residues
Discontinuous residues: P63, E64, A65, K66, Q67, V68, P69, V70, P239, V242, Y251, M253, S254, L256, E257, S259, E262, Y366, N368, F369, D370, L422, E424, F425, L428, L429
Source molecule (GenBank): Q7B8V4
Assay category: BCell
Result: Positive

Epitope: Epitope of VHH JPU-C10 on BoNT/A LC
Chemical type: Discontinuous protein residues
Discontinuous residues: P63, E64, A65, K66, Q67, V68, P69, V70, P239, V242, Y251, M253, S254, L256, E257, S259, E262, Y366, N368, F369, D370, L422, E424, F425, L428, L429
Source molecule (GenBank): Q7B8V4
Assay category: BCell
Result: Positive
Quantitative measurement: 0.2

Epitope: Epitope of VHH JPU-C10 on BoNT/A LC
Chemical type: Discontinuous protein residues
Discontinuous residues: P63, E64, A65, K66, Q67, V68, P69, V70, P239, V242, Y251, M253, S254, L256, E257, S259, E262, Y366, N368, F369, D370, L422, E424, F425, L428, L429
Source molecule (GenBank): Q7B8V4
Assay category: BCell
Result: Positive-High

Epitope: Epitope of VHH JPU-G11 on BoNT/A LC
Chemical type: Discontinuous protein residues
Discontinuous residues: Y99, S100, T101, D102, L103, R105, M106, T109, S110, R113, Y233, L322, K337, K340, L341, M344, I348, F357, K359
Source molecule (GenBank): Q7B8V4
Assay category: BCell
Result: Positive
Quantitative measurement: 2.86

Epitope: Epitope of VHH JPU-G11 on BoNT/A LC
Chemical type: Discontinuous protein residues
Discontinuous residues: Y99, S100, T101, D102, L103, R105, M106, T109, S110, R113, Y233, L322, K337, K340, L341, M344, I348, F357, K359
Source molecule (GenBank): Q7B8V4
Assay category: BCell
Result: Positive-High

Epitope: Epitope of VHH JPU-G11 on BoNT/A LC
Chemical type: Discontinuous protein residues
Discontinuous residues: Y99, S100, T101, D102, L103, R105, M106, T109, S110, R113, Y233, L322, K337, K340, L341, M344, I348, F357, K359
Source molecule (GenBank): Q7B8V4
Assay category: BCell
Result: Positive
Quantitative measurement: 0.5