LiteFold/IEDB huggingface dataset:
Reference: A Zamanou; M Samiotaki; G Panayotou; L Margaritis; P Lymberi. "Fine specificity and subclasses of IgG anti-actin autoantibodies differ in health and disease." Journal of autoimmunity (2003).

Epitope: Peptide P23
Chemical type: Peptide from protein
Sequence: VALDFENEMATA
Position: 186-197
Source molecule (GenBank): CAI19052.1
Assay category: BCell
Result: Negative

Epitope: Peptide P23
Chemical type: Peptide from protein
Sequence: VALDFENEMATA
Position: 186-197
Source molecule (GenBank): CAI19052.1
Assay category: BCell
Result: Negative

Epitope: Peptide P23
Chemical type: Peptide from protein
Sequence: VALDFENEMATA
Position: 186-197
Source molecule (GenBank): CAI19052.1
Assay category: BCell
Result: Negative

Epitope: Peptide P35
Chemical type: Peptide from protein
Sequence: VWIGGSILASLS
Position: 306-317
Source molecule (GenBank): CAI19052.1
Assay category: BCell
Result: Negative

Epitope: Peptide P35
Chemical type: Peptide from protein
Sequence: VWIGGSILASLS
Position: 306-317
Source molecule (GenBank): CAI19052.1
Assay category: BCell
Result: Negative

Epitope: Peptide P35
Chemical type: Peptide from protein
Sequence: VWIGGSILASLS
Position: 306-317
Source molecule (GenBank): CAI19052.1
Assay category: BCell
Result: Negative
Reference: R E Nickowitz; H J Worman. "Autoantibodies from patients with primary biliary cirrhosis recognize a restricted region within the cytoplasmic tail of nuclear pore membrane glycoprotein Gp210." The Journal of experimental medicine (1993).

Epitope: gp210 cytplasmic tail 15 amino acids region
Chemical type: Peptide from protein
Sequence: DRKASPPSGLWSPAY
Position: 1869-1883
Source molecule (GenBank): NP_445774.1
Assay category: BCell
Result: Positive
Reference: Maria Serena Longhi; Munther J Hussain; Dimitrios P Bogdanos; Alberto Quaglia; Giorgina Mieli-Vergani; Yun Ma; Diego Vergani. "Cytochrome P450IID6-specific CD8 T cell immune responses mirror disease activity in autoimmune hepatitis type 2." Hepatology (Baltimore, Md.) (2007).

Epitope: CYP2D6 p3 2-11
Chemical type: Peptide from protein
Sequence: GLEALVPLAV
Position: 2-11
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CYP2D6 p3 2-11
Chemical type: Peptide from protein
Sequence: GLEALVPLAV
Position: 2-11
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CYP2D6 p3 2-11
Chemical type: Peptide from protein
Sequence: GLEALVPLAV
Position: 2-11
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: CYP2D6 p3 2-11
Chemical type: Peptide from protein
Sequence: GLEALVPLAV
Position: 2-11
Source molecule (GenBank): P10635.2
Assay category: MhcBinding
Result: Negative

Epitope: CYP2D6 p5 393-402
Chemical type: Peptide from protein
Sequence: TTLITNLSSV
Position: 393-402
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: CYP2D6 p5 393-402
Chemical type: Peptide from protein
Sequence: TTLITNLSSV
Position: 393-402
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: CYP2D6 p5 393-402
Chemical type: Peptide from protein
Sequence: TTLITNLSSV
Position: 393-402
Source molecule (GenBank): P10635.2
Assay category: TCell
Result: Positive
Host:  5-31 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: CYP2D6 p5 393-402
Chemical type: Peptide from protein
Sequence: TTLITNLSSV
Position: 393-402
Source molecule (GenBank): P10635.2
Assay category: MhcBinding
Result: Positive
Reference: Hiroto Kita; Zhe-Xiong Lian; Judy Van de Water; Xiao-Song He; Shuji Matsumura; Marshall Kaplan; Velimir Luketic; Ross L Coppel; Aftab A Ansari; M Eric Gershwin. "Identification of HLA-A2-restricted CD8(+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendritic cells." The Journal of experimental medicine (2002).

Epitope: PDC-E2 (159-167)
Chemical type: Peptide from protein
Sequence: KLSEGDLLA
Position: 245-253
Source molecule (GenBank): EAW67174.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PDC-E2 (159-167)
Chemical type: Peptide from protein
Sequence: KLSEGDLLA
Position: 245-253
Source molecule (GenBank): EAW67174.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PDC-E2 (159-167)
Chemical type: Peptide from protein
Sequence: KLSEGDLLA
Position: 245-253
Source molecule (GenBank): EAW67174.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PDC-E2 (159-167)
Chemical type: Peptide from protein
Sequence: KLSEGDLLA
Position: 245-253
Source molecule (GenBank): EAW67174.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PDC-E2 (159-167)
Chemical type: Peptide from protein
Sequence: KLSEGDLLA
Position: 245-253
Source molecule (GenBank): EAW67174.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone
Reference: M J Rowley; T Maeda; I R Mackay; B E Loveland; G L McMullen; G Tribbick; C C Bernard. "Differing epitope selection of experimentally-induced and natural antibodies to a disease-specific autoantigen, the E2 subunit of pyruvate dehydrogenase complex (PDC-E2)." International immunology (1992).

Epitope: Human PDC-E2 eptiope APAPTP
Chemical type: Peptide from protein
Sequence: APAPTP
Position: 192-197
Source molecule (GenBank): EAW67174.1
Assay category: BCell
Result: Positive
Reference: Hiroto Kita; Shuji Matsumura; Xiao-Song He; Aftab A Ansari; Zhe-Xiong Lian; Judy Van de Water; Ross L Coppel; Marshall M Kaplan; M Eric Gershwin. "Analysis of TCR antagonism and molecular mimicry of an HLA-A0201-restricted CTL epitope in primary biliary cirrhosis." Hepatology (Baltimore, Md.) (2002).

Epitope: PDC-E2<sub>159-167</sub>
Chemical type: Peptide from protein
Sequence: KLSEGDLLA
Position: 245-253
Source molecule (GenBank): EAW67175.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PDC-E2<sub>159-167</sub>
Chemical type: Peptide from protein
Sequence: KLSEGDLLA
Position: 245-253
Source molecule (GenBank): EAW67175.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PDC-E2<sub>159-167</sub>
Chemical type: Peptide from protein
Sequence: KLSEGDLLA
Position: 245-253
Source molecule (GenBank): EAW67175.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PDC-E2<sub>159-167</sub>
Chemical type: Peptide from protein
Sequence: KLSEGDLLA
Position: 245-253
Source molecule (GenBank): EAW67175.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: PDC-E2<sub>159-167</sub>
Chemical type: Peptide from protein
Sequence: KLSEGDLLA
Position: 245-253
Source molecule (GenBank): EAW67175.1
Assay category: MhcBinding
Result: Positive

Epitope: PDC-E2<sub>159-167</sub> G5A analog
Chemical type: Peptide, no natural source
Sequence: KLSEADLLA
Assay category: MhcBinding
Result: Positive

Epitope: H1
Chemical type: Peptide from protein
Sequence: ALAEGDLLA
Position: 355-363
Source molecule (GenBank): YP_001351336.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: H1
Chemical type: Peptide from protein
Sequence: ALAEGDLLA
Position: 355-363
Source molecule (GenBank): YP_001351336.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Cell Line / Clone

Epitope: H1
Chemical type: Peptide from protein
Sequence: ALAEGDLLA
Position: 355-363
Source molecule (GenBank): YP_001351336.1
Assay category: MhcBinding
Result: Positive-High
Reference: Janet A Fairley; Chang Ling Fu; George J Giudice. "Mapping the binding sites of anti-BP180 immunoglobulin E autoantibodies in bullous pemphigoid." The Journal of investigative dermatology (2005).

Epitope: NC16A3
Chemical type: Peptide from protein
Sequence: KDRLQGMAPAAGAD
Position: 521-534
Source molecule (GenBank): Q9UMD9.3
Assay category: BCell
Result: Positive

Epitope: NC16A3
Chemical type: Peptide from protein
Sequence: KDRLQGMAPAAGAD
Position: 521-534
Source molecule (GenBank): Q9UMD9.3
Assay category: BCell
Result: Positive
Reference: D Zillikens; F Caux; J M Mascaro; U Wesselmann; E Schmidt; C Prost; J P Callen; E B Bröcker; L A Diaz; G J Giudice. "Autoantibodies in lichen planus pemphigoides react with a novel epitope within the C-terminal NC16A domain of BP180." The Journal of investigative dermatology (1999).

Epitope: NC16A3
Chemical type: Peptide from protein
Sequence: KDRLQGMAPAAGAD
Position: 521-534
Source molecule (GenBank): Q9UMD9.3
Assay category: BCell
Result: Positive
Host:  34-61 years

Epitope: NC16A3
Chemical type: Peptide from protein
Sequence: KDRLQGMAPAAGAD
Position: 521-534
Source molecule (GenBank): Q9UMD9.3
Assay category: BCell
Result: Positive
Reference: Valentina Calabresi; Marco Carrozzo; Emanuele Cozzani; Paolo Arduino; Giorgio Bertolusso; Federico Tirone; Aurora Parodi; Giovanna Zambruno; Giovanni Di Zenzo. "Oral pemphigoid autoantibodies preferentially target BP180 ectodomain." Clinical immunology (Orlando, Fla.) (2007).

Epitope: BP180 (1187-1223)
Chemical type: Peptide from protein
Sequence: GIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPP
Position: 1187-1223
Source molecule (GenBank): Q9UMD9.3
Assay category: BCell
Result: Negative
Host:  21-90 years

Epitope: BP180 (1187-1223)
Chemical type: Peptide from protein
Sequence: GIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPP
Position: 1187-1223
Source molecule (GenBank): Q9UMD9.3
Assay category: BCell
Result: Negative

Epitope: BP180 (1187-1223)
Chemical type: Peptide from protein
Sequence: GIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPP
Position: 1187-1223
Source molecule (GenBank): Q9UMD9.3
Assay category: BCell
Result: Negative
Reference: M S Lin; C L Fu; G J Giudice; M Olague-Marchan; A M Lazaro; P Stastny; L A Diaz. "Epitopes targeted by bullous pemphigoid T lymphocytes and autoantibodies map to the same sites on the bullous pemphigoid 180 ectodomain." The Journal of investigative dermatology (2000).

Epitope: NC16A3 (521-534)
Chemical type: Peptide from protein
Sequence: KDRLQGMAPAAGAD
Position: 521-534
Source molecule (GenBank): Q9UMD9.3
Assay category: BCell
Result: Positive
Host:  30-82 years

Epitope: NC16A3 (521-534)
Chemical type: Peptide from protein
Sequence: KDRLQGMAPAAGAD
Position: 521-534
Source molecule (GenBank): Q9UMD9.3
Assay category: TCell
Result: Positive
Host: M 65-74 years
Cell type: T cell CD4+
Tissue: blood
Culture conditions: Cell Line / Clone
Reference: Josep E Herrero-González; Olaf Brauns; Ralf Egner; Wolfgang Rönspeck; José M Mascaró; Marcel F Jonkman; Detlef Zillikens; Cassian Sitaru. "Immunoadsorption against two distinct epitopes on human type XVII collagen abolishes dermal-epidermal separation induced in vitro by autoantibodies from pemphigoid gestationis patients." European journal of immunology (2006).

Epitope: NC16A3 (521-534)
Chemical type: Peptide from protein
Sequence: KDRLQGMAPAAGAD
Position: 521-534
Source molecule (GenBank): Q9UMD9.3
Assay category: BCell
Result: Positive
Host: F

Epitope: BP180 (496-511)
Chemical type: Peptide from protein
Sequence: KARVDELERIRRSILP
Position: 496-511
Source molecule (GenBank): Q9UMD9.3
Assay category: BCell
Result: Positive
Host: F

Epitope: BP180 (498-513)
Chemical type: Peptide from protein
Sequence: RVDELERIRRSILPYG
Position: 498-513
Source molecule (GenBank): Q9UMD9.3
Assay category: BCell
Result: Positive
Host: F

Epitope: BP180 (518-533)
Chemical type: Peptide from protein
Sequence: RIEKDRLQGMAPAAGA
Position: 518-533
Source molecule (GenBank): Q9UMD9.3
Assay category: BCell
Result: Negative
Host: F

Epitope: BP180 (519-534)
Chemical type: Peptide from protein
Sequence: IEKDRLQGMAPAAGAD
Position: 519-534
Source molecule (GenBank): Q9UMD9.3
Assay category: BCell
Result: Negative
Host: F

Epitope: BP180 (521-536)
Chemical type: Peptide from protein
Sequence: KDRLQGMAPAAGADLD
Position: 521-536
Source molecule (GenBank): Q9UMD9.3
Assay category: BCell
Result: Negative
Host: F

Epitope: BP180 (524-539)
Chemical type: Peptide from protein
Sequence: LQGMAPAAGADLDKIG
Position: 524-539
Source molecule (GenBank): Q9UMD9.3
Assay category: BCell
Result: Negative
Host: F
Reference: Bingxin Zhang; Rui Zheng; Jing Wang; Dingfang Bu; Xuejun Zhu. "Epitopes in the linker subdomain region of envoplakin recognized by autoantibodies in paraneoplastic pemphigus patients." The Journal of investigative dermatology (2006).

Epitope: Envo peptide 7
Chemical type: Peptide from protein
Sequence: PCGEESVLLDRKSGKQYSIE
Position: 1731-1750
Source molecule (GenBank): NP_001979.2
Assay category: BCell
Result: Positive
Host:  17-57 years

Epitope: Envo peptide 7
Chemical type: Peptide from protein
Sequence: PCGEESVLLDRKSGKQYSIE
Position: 1731-1750
Source molecule (GenBank): NP_001979.2
Assay category: BCell
Result: Positive
Host:  17-57 years

Epitope: Envo peptide 7
Chemical type: Peptide from protein
Sequence: PCGEESVLLDRKSGKQYSIE
Position: 1731-1750
Source molecule (GenBank): NP_001979.2
Assay category: BCell
Result: Negative
Reference: Damien Bresson; Martine Pugnière; Françoise Roquet; Sandra A Rebuffat; Brigitte N-Guyen; Martine Cerutti; Jin Guo; Sandra M McLachlan; Basil Rapoport; Valérie Estienne; Jean Ruf; Thierry Chardès; Sylvie Péraldi-Roux. "Directed mutagenesis in region 713-720 of human thyroperoxidase assigns 713KFPED717 residues as being involved in the B domain of the discontinuous immunodominant region recognized by human autoantibodies." The Journal of biological chemistry (2004).

Epitope: T13 mAb epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K713, F714, P715, E716
Source molecule (GenBank): P07202.4
Assay category: BCell
Result: Positive
Quantitative measurement: 0.8

Epitope: T13 mAb epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K713, F714, P715, E716
Source molecule (GenBank): P07202.4
Assay category: BCell
Result: Positive
Quantitative measurement: 92000.0

Epitope: T13 mAb epitope
Chemical type: Discontinuous protein residues
Discontinuous residues: K713, F714, P715, E716
Source molecule (GenBank): P07202.4
Assay category: BCell
Result: Positive
Quantitative measurement: 0.000073
Reference: Takao Ando; Rauf Latif; Samira Daniel; Katsumi Eguchi; Terry F Davies. "Dissecting linear and conformational epitopes on the native thyrotropin receptor." Endocrinology (2004).

Epitope: TSHR (97-116)
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative
Host: F 6-8 weeks

Epitope: TSHR (352-371)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative
Host: F 6-8 weeks

Epitope: TSHR (397-415)
Chemical type: Peptide from protein
Sequence: VCTPKSDEFNPCEDIMGYK
Position: 397-415
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative
Host: F 6-8 weeks
Reference: Monika Gora; Andrzej Gardas; Philip F Watson; Paul Hobby; Anthony P Weetman; Brian J Sutton; J Paul Banga. "Key residues contributing to dominant conformational autoantigenic epitopes on thyroid peroxidase identified by mutagenesis." Biochemical and biophysical research communications (2004).

Epitope: IDR-A epitopic residue
Chemical type: Discontinuous protein residues
Discontinuous residues: R225
Source molecule (GenBank): P07202.4
Assay category: BCell
Result: Positive
Host: F 31 years

Epitope: IDR-A epitopic residue
Chemical type: Discontinuous protein residues
Discontinuous residues: R225
Source molecule (GenBank): P07202.4
Assay category: BCell
Result: Positive

Epitope: IDR-B epitopic residue
Chemical type: Discontinuous protein residues
Discontinuous residues: K627
Source molecule (GenBank): P07202.4
Assay category: BCell
Result: Positive
Host: F 31 and 73 years

Epitope: IDR-B epitopic residue
Chemical type: Discontinuous protein residues
Discontinuous residues: K627
Source molecule (GenBank): P07202.4
Assay category: BCell
Result: Positive
Reference: M Gora; A Gardas; W Wiktorowicz; P Hobby; P F Watson; A P Weetman; B J Sutton; J P Banga. "Evaluation of conformational epitopes on thyroid peroxidase by antipeptide antibody binding and mutagenesis." Clinical and experimental immunology (2004).

Epitope: Peptide 22 (536-546)
Chemical type: Peptide from protein
Sequence: DPLIRGLLARPAK
Position: 536-548
Source molecule (GenBank): P07202.4
Assay category: BCell
Result: Positive

Epitope: Peptide 22 (536-546)
Chemical type: Peptide from protein
Sequence: DPLIRGLLARPAK
Position: 536-548
Source molecule (GenBank): P07202.4
Assay category: BCell
Result: Positive

Epitope: Peptide 32 (273-286)
Chemical type: Peptide from protein
Sequence: QLPEEARPAAGTAC
Position: 273-286
Source molecule (GenBank): P07202.4
Assay category: BCell
Result: Positive

Epitope: Peptide 32 (273-286)
Chemical type: Peptide from protein
Sequence: QLPEEARPAAGTAC
Position: 273-286
Source molecule (GenBank): P07202.4
Assay category: BCell
Result: Positive
Reference: P N Pichurin; Chun-Rong Chen; Y Nagayama; O Pichurina; B Rapoport; S M McLachlan. "Evidence that factors other than particular thyrotropin receptor T cell epitopes contribute to the development of hyperthyroidism in murine Graves' disease." Clinical and experimental immunology (2004).

Epitope: hTSH-R (97-116)
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: hTSH-R (97-116)
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: hTSH-R (352-371)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: hTSH-R (352-371)
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: hTSH-R (397-415)
Chemical type: Peptide from protein
Sequence: VCTPKSDEFNPCEDIMGYK
Position: 397-415
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: hTSH-R (397-415)
Chemical type: Peptide from protein
Sequence: VCTPKSDEFNPCEDIMGYK
Position: 397-415
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Host: F 6-7 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo
Reference: Pavel N Pichurin; Oxana Pichurina; Russell C Marians; Chun-Rong Chen; Terry F Davies; Basil Rapoport; Sandra M McLachlan. "Thyrotropin receptor knockout mice: studies on immunological tolerance to a major thyroid autoantigen." Endocrinology (2004).

Epitope: hTSHR (97-116) F
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative
Host:  6-8 weeks

Epitope: hTSHR (97-116) F
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative
Host:  6-8 weeks

Epitope: hTSHR (97-116) F
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: hTSHR (97-116) F
Chemical type: Peptide from protein
Sequence: FYNLSKVTHIEIRNTRNLTY
Position: 97-116
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: hTSHR (352-371) W
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Positive
Host:  6-8 weeks

Epitope: hTSHR (352-371) W
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: BCell
Result: Negative
Host:  6-8 weeks

Epitope: hTSHR (352-371) W
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo

Epitope: hTSHR (352-371) W
Chemical type: Peptide from protein
Sequence: YYVFFEEQEDEIIGFGQELK
Position: 352-371
Source molecule (GenBank): P16473.2
Assay category: TCell
Result: Negative
Host:  6-8 weeks
Cell type: splenocyte
Tissue: spleen
Culture conditions: Direct Ex Vivo
Reference: Haiyan S Li; Hong Y Jiang; George Carayanniotis. "Modifying effects of iodine on the immunogenicity of thyroglobulin peptides." Journal of autoimmunity (2007).

Epitope: I-p2529
Chemical type: Peptide from protein
Sequence: EDSDARILAAAVWYYSL
Position: 2549-2565
Source molecule (GenBank): O08710.2
Assay category: BCell
Result: Negative
Host: F 4-6 weeks

Epitope: I-p2529
Chemical type: Peptide from protein
Sequence: EDSDARILAAAVWYYSL
Position: 2549-2565
Source molecule (GenBank): O08710.2
Assay category: BCell
Result: Positive-High
Host: F 4-6 weeks

Epitope: I-p2529
Chemical type: Peptide from protein
Sequence: EDSDARILAAAVWYYSL
Position: 2549-2565
Source molecule (GenBank): O08710.2
Assay category: BCell
Result: Positive-High
Host: F 4-6 weeks

Epitope: I-p2529
Chemical type: Peptide from protein
Sequence: EDSDARILAAAVWYYSL
Position: 2549-2565
Source molecule (GenBank): O08710.2
Assay category: TCell
Result: Positive
Host: F 4-6 weeks
Cell type: T cell
Tissue: lymph node
Culture conditions: Direct Ex Vivo

Epitope: I-p2529
Chemical type: Peptide from protein
Sequence: EDSDARILAAAVWYYSL
Position: 2549-2565
Source molecule (GenBank): O08710.2
Assay category: TCell
Result: Positive
Host: F 4-6 weeks

Epitope: I-p2529
Chemical type: Peptide from protein
Sequence: EDSDARILAAAVWYYSL
Position: 2549-2565
Source molecule (GenBank): O08710.2
Assay category: TCell
Result: Positive
Host: F 4-6 weeks
Reference: A Thrasyvoulides; M Sakarellos-Daitsiotis; G Philippou; A Souvatzoglou; C Sakarellos; P Lymberi. "B-cell autoepitopes on the acetylcholinesterase-homologous region of human thyroglobulin: association with Graves' disease and thyroid eye disease." European journal of endocrinology / European Federation of Endocrine Societies (2001).

Epitope: hTg 7
Chemical type: Peptide from protein
Sequence: SCWQPGTRTSTSPGVSEDCL
Position: 2263-2282
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 24
Chemical type: Peptide from protein
Sequence: TKLLAVSGPFHYWGPVIDGH
Position: 2467-2486
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive

Epitope: hTg 35
Chemical type: Peptide from protein
Sequence: AWAKRARGNVFMYHAPENYG
Position: 2599-2618
Source molecule (GenBank): P01266.5
Assay category: BCell
Result: Positive