Reference: Chanchan Xiao; Lipeng Mao; Zhigang Wang; Lijuan Gao; Guodong Zhu; Jun Su; Xiongfei Chen; Jun Yuan; Yutian Hu; Zhinan Yin; Jun Xie; Weiqing Ji; Haitao Niu; Feng Gao; Oscar Junhong Luo; Lianbo Xiao; Pengcheng Wang; Guobing Chen. "SARS-CoV-2 variant B.1.1.7 caused HLA-A2<sup>+</sup> CD8<sup>+</sup> T cell epitope mutations for impaired cellular immune response." iScience (2022).

Epitope: ORF 1ab I2230T-2
Chemical type: Peptide from protein
Sequence: TIWFLLLSV
Position: 2230-2238
Source molecule (GenBank): QVE03131.1
Assay category: TCell
Result: Positive
Host:  21-58 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: ORF 1ab I2230T-2
Chemical type: Peptide from protein
Sequence: TIWFLLLSV
Position: 2230-2238
Source molecule (GenBank): QVE03131.1
Assay category: TCell
Result: Positive
Host:  54-57 years
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: ORF 1ab I2230T-2
Chemical type: Peptide from protein
Sequence: TIWFLLLSV
Position: 2230-2238
Source molecule (GenBank): QVE03131.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ORF 1ab I2230T-2
Chemical type: Peptide from protein
Sequence: TIWFLLLSV
Position: 2230-2238
Source molecule (GenBank): QVE03131.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ORF 1ab I2230T-2
Chemical type: Peptide from protein
Sequence: TIWFLLLSV
Position: 2230-2238
Source molecule (GenBank): QVE03131.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ORF 1ab I2230T-2
Chemical type: Peptide from protein
Sequence: TIWFLLLSV
Position: 2230-2238
Source molecule (GenBank): QVE03131.1
Assay category: TCell
Result: Negative
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Direct Ex Vivo

Epitope: ORF 1ab I2230T-2
Chemical type: Peptide from protein
Sequence: TIWFLLLSV
Position: 2230-2238
Source molecule (GenBank): QVE03131.1
Assay category: MhcBinding
Result: Positive

Epitope: ORF 1ab 3673-3683
Chemical type: Peptide from protein
Sequence: SLSGFKLKDCV
Position: 3673-3683
Source molecule (GenBank): YP_009724389.1
Assay category: TCell
Result: Positive-Low
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: ORF 1ab 3673-3683
Chemical type: Peptide from protein
Sequence: SLSGFKLKDCV
Position: 3673-3683
Source molecule (GenBank): YP_009724389.1
Assay category: MhcBinding
Result: Positive

Epitope: S deltaHV69-70
Chemical type: Peptide from protein
Sequence: VTWFHAISG
Position: 62-70
Source molecule (GenBank): QSJ05725.1
Assay category: TCell
Result: Positive
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: S deltaHV69-70
Chemical type: Peptide from protein
Sequence: VTWFHAISG
Position: 62-70
Source molecule (GenBank): QSJ05725.1
Assay category: MhcBinding
Result: Positive

Epitope: S 136-145
Chemical type: Peptide from protein
Sequence: CNDPFLGVYY
Position: 136-145
Source molecule (GenBank): YP_009724390.1
Assay category: TCell
Result: Positive-High
Cell type: T cell CD8+
Tissue: blood
Culture conditions: Short Term Restimulated

Epitope: S 136-145
Chemical type: Peptide from protein
Sequence: CNDPFLGVYY
Position: 136-145
Source molecule (GenBank): YP_009724390.1
Assay category: MhcBinding
Result: Positive