Reference: Ge Song; Meng Yuan; Hejun Liu; Tazio Capozzola; Ryan N Lin; Jonathan L Torres; Wan-Ting He; Rami Musharrafieh; Katharina Dueker; Panpan Zhou; Sean Callaghan; Nitesh Mishra; Peter Yong; Fabio Anzanello; Gabriel Avillion; Anh Lina Vo; Xuduo Li; Yuexiu Zhang; Muzamil Makhdoomi; Ziqi Feng; Xueyong Zhu; Linghang Peng; David Nemazee; Yana Safonova; Bryan Briney; Andrew B Ward; Dennis R Burton; Ian A Wilson; Raiees Andrabi. "Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift." Cell reports (2025).

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive
Quantitative measurement: 3.3

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Low

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-High

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate

Epitope: Epitope of Fab CC25.54 on SARS-CoV2 RBD
Chemical type: Discontinuous protein residues
Discontinuous residues: Y369, S371, A372, F374, K378, C379, Y380, G381, V382, S383, P384, T385, D405, R408, A411, P412, G413, T415, D427, D428, F429, T430
Source molecule (GenBank): QHD43416.1
Assay category: BCell
Result: Positive-Intermediate