Reference: Maud Sigoillot; Marie Overtus; Magdalena Grodecka; Daniel Scholl; Abel Garcia-Pino; Toon Laeremans; Lihua He; Els Pardon; Ellen Hildebrandt; Ina Urbatsch; Jan Steyaert; John R Riordan; Cedric Govaerts. "Domain-interface dynamics of CFTR revealed by stabilizing nanobodies." Nature communications (2019).

Epitope: Epitope of nanobody D12 on CFTR NBD1
Chemical type: Discontinuous protein residues
Discontinuous residues: A457, S459, S549, G550, G551, G576, Y577, L578, D579, V580, L581, S605, K606, M607, E608, L610, I618, H620, Y625, F626, L633, L636
Source molecule (GenBank): Q20BJ8
Assay category: BCell
Result: Positive
Quantitative measurement: 2.91

Epitope: Epitope of nanobody D12 on CFTR NBD1
Chemical type: Discontinuous protein residues
Discontinuous residues: A457, S459, S549, G550, G551, G576, Y577, L578, D579, V580, L581, S605, K606, M607, E608, L610, I618, H620, Y625, F626, L633, L636
Source molecule (GenBank): Q20BJ8
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody D12 on CFTR NBD1
Chemical type: Discontinuous protein residues
Discontinuous residues: A457, S459, S549, G550, G551, G576, Y577, L578, D579, V580, L581, S605, K606, M607, E608, L610, I618, H620, Y625, F626, L633, L636
Source molecule (GenBank): Q20BJ8
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody D12 on CFTR NBD1
Chemical type: Discontinuous protein residues
Discontinuous residues: A457, S459, S549, G550, G551, G576, Y577, L578, D579, V580, L581, S605, K606, M607, E608, L610, I618, H620, Y625, F626, L633, L636
Source molecule (GenBank): Q20BJ8
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody D12 on CFTR NBD1
Chemical type: Discontinuous protein residues
Discontinuous residues: A457, S459, S549, G550, G551, G576, Y577, L578, D579, V580, L581, S605, K606, M607, E608, L610, I618, H620, Y625, F626, L633, L636
Source molecule (GenBank): Q20BJ8
Assay category: BCell
Result: Positive
Quantitative measurement: 2.99

Epitope: Epitope of nanobody D12 on CFTR NBD1
Chemical type: Discontinuous protein residues
Discontinuous residues: A457, S459, S549, G550, G551, G576, Y577, L578, D579, V580, L581, S605, K606, M607, E608, L610, I618, H620, Y625, F626, L633, L636
Source molecule (GenBank): Q20BJ8
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody D12 on CFTR NBD1
Chemical type: Discontinuous protein residues
Discontinuous residues: A457, S459, S549, G550, G551, G576, Y577, L578, D579, V580, L581, S605, K606, M607, E608, L610, I618, H620, Y625, F626, L633, L636
Source molecule (GenBank): Q20BJ8
Assay category: BCell
Result: Positive
Quantitative measurement: 1.95

Epitope: Epitope of nanobody G3a on CFTR NBD1
Chemical type: Discontinuous protein residues
Discontinuous residues: E514, Y515, R518, K522, E527, I530, A534, E535, K536, D537
Source molecule (GenBank): Q20BJ8
Assay category: BCell
Result: Positive
Quantitative measurement: 2.99

Epitope: Epitope of nanobody G3a on CFTR NBD1
Chemical type: Discontinuous protein residues
Discontinuous residues: E514, Y515, R518, K522, E527, I530, A534, E535, K536, D537
Source molecule (GenBank): Q20BJ8
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody G3a on CFTR NBD1
Chemical type: Discontinuous protein residues
Discontinuous residues: E514, Y515, R518, K522, E527, I530, A534, E535, K536, D537
Source molecule (GenBank): Q20BJ8
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody G3a on CFTR NBD1
Chemical type: Discontinuous protein residues
Discontinuous residues: E514, Y515, R518, K522, E527, I530, A534, E535, K536, D537
Source molecule (GenBank): Q20BJ8
Assay category: BCell
Result: Positive

Epitope: Epitope of nanobody G3a on CFTR NBD1
Chemical type: Discontinuous protein residues
Discontinuous residues: E514, Y515, R518, K522, E527, I530, A534, E535, K536, D537
Source molecule (GenBank): Q20BJ8
Assay category: BCell
Result: Positive
Quantitative measurement: 1100.0